## Thu Oct 17 08:36:37 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/LZS1_bin.106.fa -m mmseqs --itype genome -o LZS1_bin.106 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/LZS1_bin.106 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
LZS1_k127_1003343_0	1054217.TALC_01538	5.896e-185	596.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,241ID@183967|Thermoplasmata	183967|Thermoplasmata	L	helicase superfamily c-terminal domain	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
LZS1_k127_1003343_1	1041930.Mtc_1976	8.339e-06	49.0	COG0293@1|root,COG3269@1|root,arCOG00079@2157|Archaea,arCOG01641@2157|Archaea,2XT12@28890|Euryarchaeota,2N955@224756|Methanomicrobia	224756|Methanomicrobia	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rlmE	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,TRAM
LZS1_k127_1023669_3	1054217.TALC_01443	7.283e-05	48.0	COG0301@1|root,arCOG00038@2157|Archaea,2XUHM@28890|Euryarchaeota,241US@183967|Thermoplasmata	183967|Thermoplasmata	HP	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rhodanese,THUMP,ThiI
LZS1_k127_1023669_0	579137.Metvu_0558	3.824e-74	256.0	COG1632@1|root,arCOG04209@2157|Archaea,2XTJJ@28890|Euryarchaeota,23Q5E@183939|Methanococci	183939|Methanococci	J	Belongs to the eukaryotic ribosomal protein eL15 family	rpl15e	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
LZS1_k127_1023669_1	383372.Rcas_1179	2.349e-58	216.0	COG0731@1|root,COG0731@2|Bacteria,2G80U@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS1_k127_1023669_2	1150474.JQJI01000013_gene131	7.326e-19	90.0	2DNMM@1|root,32Y53@2|Bacteria	2|Bacteria	S	Family of unknown function (DUF5320)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5320
LZS1_k127_1036257_3	665571.STHERM_c01250	1.572e-08	58.0	COG2309@1|root,COG2309@2|Bacteria,2J605@203691|Spirochaetes	203691|Spirochaetes	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
LZS1_k127_1036257_1	1304874.JAFY01000002_gene577	5.569e-58	222.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_1036257_2	1125863.JAFN01000001_gene880	3.846e-42	161.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS1_k127_1036257_0	1236689.MMALV_13970	2.548e-71	244.0	COG0180@1|root,arCOG01887@2157|Archaea,2XSVC@28890|Euryarchaeota,3F2N6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	tRNA synthetases class I (W and Y)	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS1_k127_1036259_2	138119.DSY4970	8.953e-19	96.0	COG5598@1|root,COG5598@2|Bacteria,1V0ZE@1239|Firmicutes,24D6Y@186801|Clostridia,266YG@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
LZS1_k127_1036259_1	1125863.JAFN01000001_gene880	5.266e-42	161.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS1_k127_1036259_0	1236689.MMALV_13970	3.493e-71	244.0	COG0180@1|root,arCOG01887@2157|Archaea,2XSVC@28890|Euryarchaeota,3F2N6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	tRNA synthetases class I (W and Y)	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS1_k127_1038121_3	579137.Metvu_0558	5.945e-61	213.0	COG1632@1|root,arCOG04209@2157|Archaea,2XTJJ@28890|Euryarchaeota,23Q5E@183939|Methanococci	183939|Methanococci	J	Belongs to the eukaryotic ribosomal protein eL15 family	rpl15e	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02877	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L15e
LZS1_k127_1038121_4	1054217.TALC_01443	2.175e-44	172.0	COG0301@1|root,arCOG00038@2157|Archaea,2XUHM@28890|Euryarchaeota,241US@183967|Thermoplasmata	183967|Thermoplasmata	HP	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rhodanese,THUMP,ThiI
LZS1_k127_1038121_1	909663.KI867150_gene247	9.129e-150	486.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_1038121_2	545243.BAEV01000080_gene2968	1.037e-130	431.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia,36ED9@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_1038121_0	273057.SSO1218	2.461e-169	546.0	COG1012@1|root,arCOG01252@2157|Archaea,2XRV5@28889|Crenarchaeota	28889|Crenarchaeota	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS1_k127_1038121_5	1166018.FAES_3190	0.0004807	51.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4PP08@976|Bacteroidetes,47YNY@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1049086_3	525903.Taci_1023	6.605e-25	113.0	COG4974@1|root,COG4974@2|Bacteria,3T9Y4@508458|Synergistetes	508458|Synergistetes	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS1_k127_1049086_1	1236689.MMALV_08210	4.288e-93	322.0	COG0470@1|root,arCOG00470@2157|Archaea,2XT81@28890|Euryarchaeota,3F2FB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcL	-	-	ko:K04800	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,Rad17
LZS1_k127_1049086_0	673860.AciM339_0566	1.118e-109	367.0	COG0731@1|root,arCOG04174@2157|Archaea,2XSTF@28890|Euryarchaeota,3F2ET@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe)	taw1	-	4.1.3.44	ko:K15449	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,Wyosine_form
LZS1_k127_1049086_2	1236689.MMALV_09200	2.555e-64	223.0	COG1782@1|root,arCOG00543@2157|Archaea,2XTIM@28890|Euryarchaeota,3F2GJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	KH domain	epf2	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_2,KH_7,Lactamase_B,Lactamase_B_6,RMMBL
LZS1_k127_1051430_1	255470.cbdbA734	6.648e-79	271.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2G82Q@200795|Chloroflexi,34CXZ@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1051430_0	1054217.TALC_01456	7.077e-139	451.0	COG0533@1|root,arCOG01183@2157|Archaea,2Y86G@28890|Euryarchaeota	28890|Euryarchaeota	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity	kae1	GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
LZS1_k127_1051430_2	694429.Pyrfu_0838	4.509e-15	76.0	COG2423@1|root,arCOG01035@2157|Archaea,2XQE5@28889|Crenarchaeota	28889|Crenarchaeota	E	PFAM Ornithine cyclodeaminase mu-crystallin	ocd	-	1.4.1.1	ko:K19244	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
LZS1_k127_1064558_6	647113.Metok_0149	3.709e-33	133.0	COG1014@1|root,arCOG01602@2157|Archaea,2XUK0@28890|Euryarchaeota,23QJ8@183939|Methanococci	183939|Methanococci	C	PFAM Pyruvate	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
LZS1_k127_1064558_1	679926.Mpet_2272	1.529e-97	334.0	COG1013@1|root,arCOG01599@2157|Archaea,2XUSE@28890|Euryarchaeota,2NBH3@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
LZS1_k127_1064558_0	419665.Maeo_0479	5.904e-118	390.0	COG0674@1|root,arCOG01607@2157|Archaea,2Y7K5@28890|Euryarchaeota,23RI4@183939|Methanococci	183939|Methanococci	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
LZS1_k127_1064558_7	679926.Mpet_2274	3.016e-15	79.0	COG1146@1|root,arCOG00959@2157|Archaea,2XZY3@28890|Euryarchaeota	28890|Euryarchaeota	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	korD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7
LZS1_k127_1064558_2	373903.Hore_00620	3.338e-96	323.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WA9Y@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
LZS1_k127_1064558_4	552811.Dehly_1384	1.36e-44	169.0	COG1280@1|root,COG1280@2|Bacteria,2GBTY@200795|Chloroflexi,34CQW@301297|Dehalococcoidia	301297|Dehalococcoidia	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
LZS1_k127_1064558_3	351627.Csac_2430	1.304e-53	196.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,42GAI@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Rubrerythrin	rbr	GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS1_k127_1064558_5	1236689.MMALV_09970	6.41e-38	147.0	COG1591@1|root,arCOG00919@2157|Archaea,2XY2Q@28890|Euryarchaeota,3F2NJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Archaeal holliday junction resolvase (hjc)	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
LZS1_k127_1066616_2	880072.Desac_0915	1.291e-35	139.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,2MQ4H@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_1066616_1	192952.MM_1365	1.336e-63	231.0	COG0611@1|root,arCOG00638@2157|Archaea,2XSUK@28890|Euryarchaeota,2N9G5@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS1_k127_1066616_0	1232437.KL662001_gene4644	6.12e-129	424.0	COG3875@1|root,COG3875@2|Bacteria,1R79Y@1224|Proteobacteria,42PGD@68525|delta/epsilon subdivisions,2WMB6@28221|Deltaproteobacteria,2MJB5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
LZS1_k127_1066616_3	1236689.MMALV_14890	2.723e-26	111.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y696@28890|Euryarchaeota,3F2WC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
LZS1_k127_1076043_0	1219084.AP014508_gene74	6.756e-43	176.0	COG0747@1|root,COG0747@2|Bacteria,2GC5G@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_1079009_12	1236689.MMALV_03220	2.492e-60	214.0	COG1601@1|root,COG3269@1|root,arCOG01640@2157|Archaea,arCOG01641@2157|Archaea,2XTVZ@28890|Euryarchaeota,3F2N9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2b	-	-	ko:K03238	ko03013,map03013	-	-	-	ko00000,ko00001,ko01009,ko03012	-	-	-	TRAM,eIF-5_eIF-2B
LZS1_k127_1079009_15	797114.C475_20787	2.131e-46	180.0	COG0384@1|root,arCOG02256@2157|Archaea,2XUVT@28890|Euryarchaeota,23RZN@183963|Halobacteria	183963|Halobacteria	S	Phenazine biosynthesis protein phzf family	phzF	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
LZS1_k127_1079009_11	1094980.Mpsy_1566	4.121e-61	222.0	COG3389@1|root,arCOG04463@2157|Archaea,2XSZT@28890|Euryarchaeota,2N9I2@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART Peptidase A22, presenilin signal peptide	-	-	-	-	-	-	-	-	-	-	-	-	SPP
LZS1_k127_1079009_17	593117.TGAM_1037	9.485e-35	140.0	COG2129@1|root,arCOG01145@2157|Archaea,2XXMZ@28890|Euryarchaeota,245B2@183968|Thermococci	183968|Thermococci	S	Metallophosphoesterase, calcineurin superfamily	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
LZS1_k127_1079009_16	1236689.MMALV_03100	1.303e-37	150.0	COG2007@1|root,arCOG04154@2157|Archaea,2XYXX@28890|Euryarchaeota,3F2SE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal protein S8e	rps8e	GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K02995	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8e
LZS1_k127_1079009_8	1343739.PAP_06020	2.842e-88	316.0	COG0312@1|root,arCOG00322@2157|Archaea,2XVT5@28890|Euryarchaeota,2435V@183968|Thermococci	183968|Thermococci	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS1_k127_1079009_0	439481.Aboo_1233	4.595e-125	416.0	COG1530@1|root,arCOG00321@2157|Archaea,2XU9U@28890|Euryarchaeota,3F33F@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS1_k127_1079009_23	453591.Igni_0768	3.264e-11	76.0	COG1400@1|root,arCOG01217@2157|Archaea,2XR4P@28889|Crenarchaeota	28889|Crenarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP	srp19	-	-	ko:K03105	ko03060,map03060	-	-	-	ko00000,ko00001,ko02044	3.A.5.7,3.A.5.9	-	-	SRP19
LZS1_k127_1079009_19	673860.AciM339_1541	3.713e-28	116.0	COG1888@1|root,arCOG04140@2157|Archaea,2Y02A@28890|Euryarchaeota,3F3DR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Uncharacterized ArCR, COG1888	-	-	-	ko:K09732	-	-	-	-	ko00000	-	-	-	DUF211
LZS1_k127_1079009_3	384616.Pisl_1934	7.084e-114	386.0	COG0063@1|root,arCOG00018@2157|Archaea,2XPXN@28889|Crenarchaeota	28889|Crenarchaeota	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
LZS1_k127_1079009_13	1236689.MMALV_03070	1.601e-52	195.0	COG1407@1|root,arCOG01150@2157|Archaea,2XU3W@28890|Euryarchaeota,3F2TS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Calcineurin-like phosphoesterase superfamily domain	rpe	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
LZS1_k127_1079009_14	429009.Adeg_1691	7.189e-49	194.0	COG4739@1|root,COG4739@2|Bacteria,1V3K5@1239|Firmicutes,24INA@186801|Clostridia,42FIV@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized protein containing a ferredoxin domain (DUF2148)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2148
LZS1_k127_1079009_25	176946.XP_007443313.1	0.0001154	55.0	KOG1721@1|root,KOG1721@2759|Eukaryota	176946.XP_007443313.1|-	B	DNA binding	-	-	-	ko:K09228	-	-	-	-	ko00000,ko03000	-	-	-	-
LZS1_k127_1079009_2	439481.Aboo_0589	1.795e-120	398.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F38N@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS1_k127_1079009_1	673860.AciM339_0142	4.502e-123	409.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F32D@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS1_k127_1079009_26	269797.Mbar_A2502	0.000488	48.0	COG1369@1|root,arCOG01365@2157|Archaea,2XX63@28890|Euryarchaeota	28890|Euryarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp2	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03537	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	RNase_P_Rpp14
LZS1_k127_1079009_4	1236689.MMALV_03010	7.478e-99	327.0	COG0638@1|root,arCOG00971@2157|Archaea,2XUKA@28890|Euryarchaeota,3F2G0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome,Proteasome_A_N
LZS1_k127_1079009_7	439481.Aboo_0184	1.487e-88	297.0	COG1500@1|root,arCOG04187@2157|Archaea,2XTNH@28890|Euryarchaeota,3F2JN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Shwachman-Bodian-Diamond syndrome (SBDS) protein	-	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K14574	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	SBDS,SBDS_C
LZS1_k127_1079009_9	439481.Aboo_0183	1.51e-75	263.0	COG1097@1|root,arCOG00678@2157|Archaea,2XWEN@28890|Euryarchaeota,3F2JY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome	rrp4	GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K03679	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,KH_1,KH_6,S1
LZS1_k127_1079009_5	439481.Aboo_0182	7.912e-98	326.0	COG0689@1|root,arCOG01575@2157|Archaea,2XVHI@28890|Euryarchaeota,3F2GE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails	rrp41	GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354	-	ko:K11600	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
LZS1_k127_1079009_6	439481.Aboo_0181	1.023e-89	302.0	COG2123@1|root,arCOG01574@2157|Archaea,2XWTK@28890|Euryarchaeota,3F2JS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site	rrp42	GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354	-	ko:K12589	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	RNase_PH,RNase_PH_C
LZS1_k127_1079009_21	1236689.MMALV_02960	2.863e-17	85.0	COG1997@1|root,arCOG04208@2157|Archaea,2Y6HQ@28890|Euryarchaeota,3F2TK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl37ae	-	-	ko:K02921	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37ae
LZS1_k127_1079009_22	1236689.MMALV_02950	1.548e-11	65.0	COG1996@1|root,arCOG04341@2157|Archaea,2Y5VN@28890|Euryarchaeota	28890|Euryarchaeota	K	DNA directed RNA polymerase, 7 kDa subunit	-	-	2.7.7.6	ko:K03059	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	DNA_RNApol_7kD
LZS1_k127_1079009_24	673860.AciM339_1451	1.535e-05	53.0	COG2892@1|root,arCOG04414@2157|Archaea,2Y77T@28890|Euryarchaeota,3F3IZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Transcription factor Pcc1	-	-	-	ko:K09741	-	-	-	-	ko00000,ko03016	-	-	-	Pcc1
LZS1_k127_1079009_20	368407.Memar_1672	1.072e-21	98.0	COG1382@1|root,arCOG01342@2157|Archaea,2XX88@28890|Euryarchaeota,2N9TP@224756|Methanomicrobia	224756|Methanomicrobia	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdB	-	-	ko:K04798	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin_2
LZS1_k127_1079009_10	1054217.TALC_00321	5.655e-72	254.0	COG0618@1|root,arCOG01565@2157|Archaea,2XWQV@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
LZS1_k127_1079009_18	673860.AciM339_0044	3.683e-34	135.0	COG0162@1|root,arCOG01886@2157|Archaea,2XTA0@28890|Euryarchaeota,3F2HA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
LZS1_k127_1085886_3	351160.LRC332	1.623e-19	98.0	arCOG01190@1|root,arCOG01190@2157|Archaea	351160.LRC332|-	G	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1085886_0	138119.DSY3156	1.237e-64	240.0	COG5598@1|root,COG5598@2|Bacteria,1UY21@1239|Firmicutes,248BQ@186801|Clostridia,260DN@186807|Peptococcaceae	186801|Clostridia	H	PFAM Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
LZS1_k127_1085886_2	386456.JQKN01000001_gene2138	1.173e-50	195.0	COG0842@1|root,arCOG01467@2157|Archaea	2157|Archaea	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS1_k127_1085886_1	479434.Sthe_2671	4.127e-62	227.0	COG1131@1|root,COG1131@2|Bacteria,2G7V6@200795|Chloroflexi,27Y6R@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_1085953_0	880072.Desac_2171	3.449e-73	269.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
LZS1_k127_1085953_3	1041930.Mtc_2483	7.039e-35	150.0	COG1784@1|root,arCOG04469@2157|Archaea,2XSZ3@28890|Euryarchaeota,2N9A6@224756|Methanomicrobia	224756|Methanomicrobia	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K08971	-	-	-	-	ko00000	-	-	-	TctA
LZS1_k127_1085953_1	877455.Metbo_0197	1.072e-53	198.0	COG0503@1|root,arCOG00030@2157|Archaea,2XTWM@28890|Euryarchaeota,23P15@183925|Methanobacteria	183925|Methanobacteria	F	Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis	hpt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
LZS1_k127_1085953_2	1304284.L21TH_1260	3.118e-49	184.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,36HZI@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
LZS1_k127_1121310_1	673860.AciM339_0330	2.264e-57	213.0	COG0517@1|root,arCOG00600@2157|Archaea,2XU4J@28890|Euryarchaeota,3F2PE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Domain in cystathionine beta-synthase and other proteins.	cbs2	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS1_k127_1121310_5	1114856.C496_12964	1.826e-22	103.0	COG0589@1|root,arCOG02053@2157|Archaea,2XX8Y@28890|Euryarchaeota,23VQJ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS1_k127_1121310_0	673860.AciM339_0424	1.826e-61	225.0	COG0402@1|root,arCOG00692@2157|Archaea,2XSYB@28890|Euryarchaeota,3F2N3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Amidohydrolase family	guaD2	-	3.5.4.1,3.5.4.3	ko:K01485,ko:K01487	ko00230,ko00240,ko00330,ko01100,map00230,map00240,map00330,map01100	-	R00974,R01411,R01676,R02922	RC00074,RC00204,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
LZS1_k127_1121310_6	1236689.MMALV_10870	1.476e-18	87.0	COG2768@1|root,arCOG02448@2157|Archaea	2157|Archaea	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
LZS1_k127_1121310_3	439481.Aboo_0448	3.982e-41	161.0	COG2339@1|root,arCOG02985@2157|Archaea	2157|Archaea	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
LZS1_k127_1121310_4	572478.Vdis_0757	1.648e-30	128.0	COG1514@1|root,arCOG01736@2157|Archaea,2XQM6@28889|Crenarchaeota	28889|Crenarchaeota	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
LZS1_k127_1121310_2	1265505.ATUG01000002_gene1134	1.166e-48	186.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42R1T@68525|delta/epsilon subdivisions,2WN88@28221|Deltaproteobacteria,2MN72@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
LZS1_k127_1126295_1	1236689.MMALV_07810	1.128e-38	153.0	COG1340@1|root,arCOG01159@2157|Archaea,2XU21@28890|Euryarchaeota,3F2P7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1126295_4	1158602.I590_00898	1.485e-05	55.0	COG4640@1|root,COG4640@2|Bacteria,1UYJN@1239|Firmicutes,4HF8I@91061|Bacilli,4AZG7@81852|Enterococcaceae	91061|Bacilli	S	response to antibiotic	tcaA	-	-	ko:K21463	-	-	-	-	ko00000	-	-	-	zf-ribbon_3,zinc_ribbon_2
LZS1_k127_1126295_3	439481.Aboo_0442	7.001e-08	59.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y75A@28890|Euryarchaeota,3F3F6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1126295_5	1041930.Mtc_2273	0.0001167	48.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZZ4@28890|Euryarchaeota,2N9YN@224756|Methanomicrobia	224756|Methanomicrobia	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
LZS1_k127_1126295_0	1009370.ALO_08133	5.73e-244	773.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,4H3M2@909932|Negativicutes	909932|Negativicutes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
LZS1_k127_1126295_2	1236689.MMALV_04370	4.612e-31	124.0	COG1095@1|root,arCOG00675@2157|Archaea,2XT6U@28890|Euryarchaeota,3F2MN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397	rpoE1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
LZS1_k127_1135836_1	1054217.TALC_00076	5.699e-132	430.0	COG0499@1|root,arCOG04137@2157|Archaea,2XT4S@28890|Euryarchaeota,241J8@183967|Thermoplasmata	183967|Thermoplasmata	F	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS1_k127_1135836_3	70601.3257894	4.675e-72	252.0	COG1701@1|root,arCOG04262@2157|Archaea,2XTAP@28890|Euryarchaeota,243IV@183968|Thermococci	183968|Thermococci	S	Phosphopantothenate/pantothenate synthetase	-	-	6.3.2.36	ko:K09722	ko00410,ko00770,ko01100,map00410,map00770,map01100	-	R09379	RC00096,RC00141	ko00000,ko00001,ko01000	-	-	-	PPS_PS
LZS1_k127_1135836_5	1333523.L593_14585	3.428e-05	49.0	COG3277@1|root,arCOG02466@2157|Archaea,2XZS0@28890|Euryarchaeota,23XMI@183963|Halobacteria	183963|Halobacteria	J	COG3277 RNA-binding protein involved in rRNA processing	gar1	-	-	ko:K07569	-	-	-	-	ko00000,ko03009	-	-	-	Gar1
LZS1_k127_1135836_0	1236689.MMALV_00330	2.354e-185	583.0	COG1405@1|root,arCOG01981@2157|Archaea,2XT0Z@28890|Euryarchaeota,3F2FH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB)	tfb	-	-	ko:K03124	ko03022,ko05169,ko05203,map03022,map05169,map05203	-	-	-	ko00000,ko00001,ko03021	-	-	-	TFIIB,TF_Zn_Ribbon
LZS1_k127_1135836_2	1462527.CCDM010000001_gene3074	4.423e-123	403.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,23JRD@182709|Oceanobacillus	91061|Bacilli	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
LZS1_k127_1135836_4	1236689.MMALV_00300	3.305e-28	115.0	COG1676@1|root,arCOG01701@2157|Archaea,2XTKB@28890|Euryarchaeota,3F2U2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	tRNA intron endonuclease, catalytic C-terminal domain	endA	GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
LZS1_k127_1144078_8	1120971.AUCA01000011_gene2946	3.404e-31	130.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,4HIVG@91061|Bacilli,278GM@186823|Alicyclobacillaceae	91061|Bacilli	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
LZS1_k127_1144078_6	1235793.C809_01089	5.338e-32	135.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,247MX@186801|Clostridia,27KZQ@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	CheC-like family	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
LZS1_k127_1144078_0	1304284.L21TH_2258	6.348e-123	418.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,36DR0@31979|Clostridiaceae	186801|Clostridia	NT	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
LZS1_k127_1144078_2	635013.TherJR_0113	9.759e-87	299.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia,260YB@186807|Peptococcaceae	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
LZS1_k127_1144078_5	1033737.CAEV01000010_gene2435	2.694e-33	132.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,36IRR@31979|Clostridiaceae	186801|Clostridia	NT	Chemotaxis protein cheY	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
LZS1_k127_1144078_7	1121456.ATVA01000016_gene2000	8.463e-32	129.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5TT@28221|Deltaproteobacteria,2MGVV@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS1_k127_1144078_4	1094980.Mpsy_1292	8.811e-47	192.0	COG0840@1|root,arCOG02342@1|root,arCOG02318@2157|Archaea,arCOG02342@2157|Archaea,arCOG02344@2157|Archaea,2Y7N2@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS,PAS_4,PAS_9
LZS1_k127_1144078_3	1038922.PflQ2_2775	1.113e-48	184.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RX4G@1236|Gammaproteobacteria,1YT0D@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,Response_reg
LZS1_k127_1144078_1	639282.DEFDS_1968	2.952e-109	361.0	COG0115@1|root,COG0115@2|Bacteria,2GEYI@200930|Deferribacteres	200930|Deferribacteres	E	Amino-transferase class IV	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS1_k127_1144078_9	304371.MCP_1551	3.024e-12	66.0	COG0179@1|root,arCOG00235@2157|Archaea,2XU30@28890|Euryarchaeota,2N9DN@224756|Methanomicrobia	224756|Methanomicrobia	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
LZS1_k127_1163599_12	439481.Aboo_0644	2.597e-39	154.0	COG2095@1|root,arCOG01997@2157|Archaea,2XZEI@28890|Euryarchaeota,3F2SG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
LZS1_k127_1163599_16	511051.CSE_10780	4.234e-16	89.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_1163599_7	926569.ANT_28000	1.206e-52	206.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
LZS1_k127_1163599_13	479434.Sthe_3005	3.414e-36	143.0	COG0663@1|root,COG0663@2|Bacteria,2G70N@200795|Chloroflexi,27YHR@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
LZS1_k127_1163599_14	289376.THEYE_A1199	3.818e-23	109.0	COG0011@1|root,COG0011@2|Bacteria,3J0QD@40117|Nitrospirae	40117|Nitrospirae	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
LZS1_k127_1163599_9	1236689.MMALV_01660	5.18e-41	156.0	arCOG03678@1|root,arCOG03678@2157|Archaea,2XZ63@28890|Euryarchaeota,3F2RS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1163599_0	1236689.MMALV_01670	1.979e-152	503.0	COG1199@1|root,arCOG00770@2157|Archaea,2XTH2@28890|Euryarchaeota,3F2IN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	HELICc2	rad3b	-	3.6.4.12	ko:K03722,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD_2,HBB,Helicase_C_2,ResIII
LZS1_k127_1163599_6	1236689.MMALV_02110	2.837e-60	213.0	COG0575@1|root,arCOG04106@2157|Archaea,2XWNR@28890|Euryarchaeota,3F2PX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids	carS	-	2.7.7.67	ko:K19664	ko00564,map00564	-	R08966	RC00002	ko00000,ko00001,ko01000	-	-	-	CarS-like
LZS1_k127_1163599_11	1236689.MMALV_02120	5.103e-40	154.0	COG0461@1|root,arCOG00029@2157|Archaea,2XVNG@28890|Euryarchaeota,3F2Q0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS1_k127_1163599_10	351160.RRC526	1.1e-40	164.0	COG1573@1|root,arCOG00905@2157|Archaea,2XUVI@28890|Euryarchaeota,2N9TK@224756|Methanomicrobia	224756|Methanomicrobia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS1_k127_1163599_15	383372.Rcas_2277	3.589e-21	109.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
LZS1_k127_1163599_4	439481.Aboo_0520	9.762e-77	264.0	COG0463@1|root,arCOG00894@2157|Archaea,2XUJ6@28890|Euryarchaeota,3F38U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_1163599_3	673860.AciM339_0524	9.395e-90	303.0	COG0463@1|root,arCOG01385@2157|Archaea,2XUEP@28890|Euryarchaeota,3F30S@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase family 2	aglI	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_1163599_1	195522.BD01_1333	2.429e-125	414.0	COG1004@1|root,arCOG00253@2157|Archaea,2XTQY@28890|Euryarchaeota,242NM@183968|Thermococci	183968|Thermococci	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS1_k127_1163599_2	867903.ThesuDRAFT_01872	2.541e-103	346.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,3WCRM@538999|Clostridiales incertae sedis	186801|Clostridia	M	MobA-like NTP transferase domain	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS1_k127_1163599_8	693661.Arcve_0563	1.638e-46	172.0	COG0110@1|root,arCOG01848@2157|Archaea,2XWJM@28890|Euryarchaeota	28890|Euryarchaeota	E	COG0110 Acetyltransferase (isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
LZS1_k127_1163599_5	370438.PTH_0393	2.35e-67	244.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,261AB@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS1_k127_1188059_0	273116.14324671	1.892e-143	460.0	COG0468@1|root,arCOG00415@2157|Archaea,2XT80@28890|Euryarchaeota,241KB@183967|Thermoplasmata	183967|Thermoplasmata	L	Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules	radA	-	-	ko:K04483	-	-	-	-	ko00000,ko03400	-	-	-	HHH_5,Rad51
LZS1_k127_1188059_6	1236689.MMALV_02580	1.167e-45	177.0	COG1041@1|root,arCOG00047@2157|Archaea,2XTD6@28890|Euryarchaeota,3F2QX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Pfam:Methyltransf_26	trmG10	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	2.1.1.213	ko:K07446	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP,UPF0020
LZS1_k127_1188059_2	439481.Aboo_1446	5.739e-93	328.0	COG0750@1|root,arCOG00609@2157|Archaea,2XT29@28890|Euryarchaeota,3F2WK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
LZS1_k127_1188059_4	673860.AciM339_0295	7.578e-65	233.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,3F2N5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	UbiA prenyltransferase family	ubiA	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
LZS1_k127_1188059_3	439481.Aboo_0770	1.358e-70	251.0	COG1646@1|root,arCOG01085@2157|Archaea,2XTEC@28890|Euryarchaeota,3F2M3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids	pcrB	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	2.5.1.41	ko:K17104	ko00564,map00564	-	R04158	RC01091	ko00000,ko00001,ko01000	-	-	-	PcrB
LZS1_k127_1188059_1	485913.Krac_1224	1.131e-114	388.0	COG1680@1|root,COG1680@2|Bacteria,2G6QM@200795|Chloroflexi	2|Bacteria	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS1_k127_1188059_5	797209.ZOD2009_15561	1.357e-50	196.0	COG0624@1|root,arCOG01107@2157|Archaea,2XVEH@28890|Euryarchaeota,23V2I@183963|Halobacteria	183963|Halobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS1_k127_1188059_7	439481.Aboo_0152	1.203e-08	56.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,3F32N@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	cobW
LZS1_k127_1223068_1	1054217.TALC_01448	8.874e-05	46.0	arCOG14617@1|root,arCOG14617@2157|Archaea,2Y5TW@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1223068_0	1123228.AUIH01000092_gene552	1.295e-93	332.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,1RA9Y@1224|Proteobacteria,1T5TQ@1236|Gammaproteobacteria,1XNA1@135619|Oceanospirillales	135619|Oceanospirillales	G	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1242575_4	572546.Arcpr_0708	6.798e-65	230.0	COG0527@1|root,arCOG00861@2157|Archaea,2XTJ0@28890|Euryarchaeota,245WW@183980|Archaeoglobi	183980|Archaeoglobi	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
LZS1_k127_1242575_1	436308.Nmar_0696	1.061e-94	321.0	COG0460@1|root,arCOG01351@2157|Archaea,41SAC@651137|Thaumarchaeota	651137|Thaumarchaeota	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
LZS1_k127_1242575_0	644281.MFS40622_0653	1.041e-142	463.0	COG0498@1|root,arCOG01434@2157|Archaea,2XT84@28890|Euryarchaeota,23QKS@183939|Methanococci	183939|Methanococci	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS1_k127_1242575_3	391623.TERMP_00415	2.208e-65	235.0	COG0083@1|root,arCOG01027@2157|Archaea,2XUDU@28890|Euryarchaeota,243D9@183968|Thermococci	183968|Thermococci	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	-	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS1_k127_1242575_2	1121342.AUCO01000027_gene1256	4.729e-68	238.0	COG0017@1|root,COG0017@2|Bacteria,1UFEI@1239|Firmicutes,24EYB@186801|Clostridia,36GED@31979|Clostridiaceae	186801|Clostridia	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2
LZS1_k127_1257733_1	1236689.MMALV_15400	1.849e-66	237.0	COG0030@1|root,arCOG04131@2157|Archaea,2XU1Q@28890|Euryarchaeota,3F2MQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
LZS1_k127_1257733_0	1128427.KB904821_gene1757	1.009e-92	316.0	COG3367@1|root,COG3367@2|Bacteria,1G2EW@1117|Cyanobacteria,1H7D6@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
LZS1_k127_1277824_1	1236689.MMALV_02170	1.447e-23	103.0	COG1196@1|root,arCOG00371@2157|Archaea,2XSVK@28890|Euryarchaeota,3F2HY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
LZS1_k127_1277824_0	673860.AciM339_0819	1.487e-44	177.0	COG0438@1|root,arCOG01410@2157|Archaea,2XYAQ@28890|Euryarchaeota,3F3FW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS1_k127_1285997_0	304371.MCP_1358	2.38e-153	503.0	COG0175@1|root,COG2221@1|root,arCOG00073@2157|Archaea,arCOG02059@2157|Archaea,2Y7JD@28890|Euryarchaeota,2N9AR@224756|Methanomicrobia	224756|Methanomicrobia	E	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,PAPS_reduct
LZS1_k127_1285997_3	1054217.TALC_01284	1.21e-14	84.0	arCOG13491@1|root,arCOG13491@2157|Archaea,2Y2FU@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1285997_4	768679.TTX_0473	2.775e-05	53.0	arCOG05509@1|root,arCOG05509@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1922
LZS1_k127_1285997_2	1094980.Mpsy_2611	4.057e-15	88.0	COG0745@1|root,arCOG02348@1|root,arCOG03799@1|root,arCOG02348@2157|Archaea,arCOG02592@2157|Archaea,arCOG03799@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF835)	-	-	2.7.7.65,6.3.4.2	ko:K01937,ko:K02488	ko00240,ko01100,ko02020,ko04112,map00240,map01100,map02020,map04112	M00052,M00511	R00571,R00573,R08057	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	DUF835,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_1285997_1	867845.KI911784_gene1447	1.98e-35	142.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
LZS1_k127_1290297_5	1054217.TALC_01455	6.304e-31	129.0	COG0608@1|root,arCOG00427@2157|Archaea,2XW5A@28890|Euryarchaeota,241PR@183967|Thermoplasmata	183967|Thermoplasmata	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHH,DHHA1
LZS1_k127_1290297_3	1236689.MMALV_15580	1.286e-48	177.0	COG0184@1|root,arCOG04185@2157|Archaea,2XWKV@28890|Euryarchaeota,3F2PA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal S13/S15 N-terminal domain	rps15	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13_N,Ribosomal_S15
LZS1_k127_1290297_8	351160.RCIX2092	5.511e-23	110.0	COG0494@1|root,arCOG01078@2157|Archaea,2Y89N@28890|Euryarchaeota	28890|Euryarchaeota	L	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS1_k127_1290297_2	1054217.TALC_01452	8.8e-55	199.0	COG0513@1|root,arCOG00078@2157|Archaea,2XTFM@28890|Euryarchaeota,241RY@183967|Thermoplasmata	183967|Thermoplasmata	J	Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA	flpA	-	-	ko:K04795	-	-	-	-	ko00000,ko03009	-	-	-	Fibrillarin
LZS1_k127_1290297_7	439481.Aboo_0106	3.031e-27	117.0	arCOG00743@1|root,arCOG00743@2157|Archaea,2Y3FU@28890|Euryarchaeota,3F3AW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1290297_9	1042877.GQS_09815	7.932e-06	53.0	arCOG04079@1|root,arCOG04079@2157|Archaea,2Y184@28890|Euryarchaeota,2448K@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1290297_6	269797.Mbar_A2190	1.079e-28	125.0	COG0483@1|root,arCOG01349@2157|Archaea,2XUBB@28890|Euryarchaeota,2N9NZ@224756|Methanomicrobia	224756|Methanomicrobia	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
LZS1_k127_1290297_1	1236689.MMALV_15550	4.285e-62	228.0	COG0061@1|root,COG0483@1|root,arCOG01348@2157|Archaea,arCOG01349@2157|Archaea,2XTP6@28890|Euryarchaeota	28890|Euryarchaeota	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Inositol_P,NAD_kinase
LZS1_k127_1290297_4	1094980.Mpsy_0362	3.709e-33	133.0	COG1310@1|root,arCOG01139@2157|Archaea,2XWKU@28890|Euryarchaeota,2N9TM@224756|Methanomicrobia	224756|Methanomicrobia	S	Prokaryotic homologs of the JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
LZS1_k127_1290297_0	565033.GACE_1114	2.651e-62	217.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,245ZX@183980|Archaeoglobi	183980|Archaeoglobi	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS1_k127_1294441_1	1236689.MMALV_03830	5.807e-44	168.0	arCOG14795@1|root,arCOG14795@2157|Archaea,2Y31Z@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1294441_0	1094980.Mpsy_0967	2.562e-184	583.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota,2N9HE@224756|Methanomicrobia	224756|Methanomicrobia	F	Protein of unknown function (DUF1246)	-	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
LZS1_k127_1294441_2	1296415.JACC01000020_gene3775	1.636e-12	82.0	COG1858@1|root,COG3209@1|root,COG3291@1|root,COG3391@1|root,COG4412@1|root,COG4733@1|root,COG5276@1|root,COG1858@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,COG5276@2|Bacteria,4NIPP@976|Bacteroidetes,1I7A8@117743|Flavobacteriia,2YKAC@290174|Aquimarina	976|Bacteroidetes	MP	Cellulose binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_3,Cytochrom_C,Cytochrom_D1,PKD
LZS1_k127_1301817_0	1236689.MMALV_01710	9.452e-53	192.0	COG1096@1|root,arCOG00676@2157|Archaea,2XYYA@28890|Euryarchaeota	28890|Euryarchaeota	J	Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs	csl4	-	-	ko:K07573	ko03018,map03018	M00390,M00391	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	ECR1_N,EXOSC1
LZS1_k127_1301817_1	981369.JQMJ01000004_gene5827	4.705e-05	51.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,2NFZK@228398|Streptacidiphilus	201174|Actinobacteria	E	Serine hydroxymethyltransferase	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
LZS1_k127_1327594_4	1236689.MMALV_00110	2.511e-11	64.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,3F2G5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
LZS1_k127_1327594_1	1054217.TALC_00009	9.689e-24	103.0	COG1436@1|root,arCOG04102@2157|Archaea,2XXYI@28890|Euryarchaeota	28890|Euryarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
LZS1_k127_1327594_0	304371.MCP_0341	2.592e-77	271.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,2N9HH@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0388	vATP-synt_AC39
LZS1_k127_1327594_2	351160.RCIX2027	9.217e-21	99.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,2N9TB@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
LZS1_k127_1327594_3	869210.Marky_1604	1.179e-16	81.0	COG0636@1|root,COG0636@2|Bacteria,1WK69@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM ATP synthase subunit C	atpP	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
LZS1_k127_1354344_1	868131.MSWAN_1005	8.252e-104	357.0	COG1148@1|root,arCOG02236@2157|Archaea,2XV85@28890|Euryarchaeota,23PDJ@183925|Methanobacteria	183925|Methanobacteria	C	PFAM Methyl-viologen-reducing hydrogenase, delta subunit	-	-	1.8.7.3	ko:K22480	ko00680,map00680	-	R11931	RC00011	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_7,FlpD,NAD_binding_8,Pyr_redox_2
LZS1_k127_1354344_4	673860.AciM339_0736	0.0003365	45.0	arCOG13506@1|root,arCOG13506@2157|Archaea,2Y76D@28890|Euryarchaeota,3F3GT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1354344_3	1054217.TALC_01541	7.122e-53	197.0	COG1772@1|root,arCOG04364@2157|Archaea,2XXJ6@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF531)	-	-	-	ko:K09725	-	-	-	-	ko00000	-	-	-	DUF531
LZS1_k127_1354344_0	1054217.TALC_01540	1.525e-129	423.0	COG0150@1|root,arCOG00639@2157|Archaea,2XTBA@28890|Euryarchaeota,241K3@183967|Thermoplasmata	183967|Thermoplasmata	F	phosphoribosylformylglycinamidine cyclo-ligase activity	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS1_k127_1354344_2	192952.MM_2288	1.798e-53	194.0	COG0293@1|root,arCOG00079@2157|Archaea,2XT12@28890|Euryarchaeota,2N955@224756|Methanomicrobia	224756|Methanomicrobia	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	rlmE	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,TRAM
LZS1_k127_1373560_0	864051.BurJ1DRAFT_4382	4.74e-38	151.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,1KIXF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS1_k127_1373560_1	1121445.ATUZ01000017_gene2086	7.266e-17	89.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2M8RV@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
LZS1_k127_1391125_0	1183377.Py04_0221	5.774e-27	118.0	COG0675@1|root,arCOG00679@2157|Archaea,2XYA2@28890|Euryarchaeota,2430I@183968|Thermococci	183968|Thermococci	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
LZS1_k127_1457647_2	304371.MCP_0419	5.363e-77	260.0	COG0365@1|root,arCOG04201@2157|Archaea,2XSTQ@28890|Euryarchaeota,2NBH4@224756|Methanomicrobia	224756|Methanomicrobia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS1_k127_1457647_6	204773.HEAR1076	1.617e-33	137.0	COG0288@1|root,COG0288@2|Bacteria,1QX11@1224|Proteobacteria	1224|Proteobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
LZS1_k127_1457647_3	649639.Bcell_2236	2.288e-76	272.0	COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli,1ZAP4@1386|Bacillus	91061|Bacilli	P	Major facilitator superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
LZS1_k127_1457647_5	673860.AciM339_0095	3.372e-65	231.0	COG1859@1|root,arCOG04063@2157|Archaea,2XWPC@28890|Euryarchaeota,3F2KG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase	kptA	-	-	ko:K07559	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PTS_2-RNA
LZS1_k127_1457647_8	304371.MCP_1176	5.1e-17	91.0	arCOG03129@1|root,arCOG03129@2157|Archaea,2XTF9@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF2797)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2797
LZS1_k127_1457647_4	693661.Arcve_1577	9.82e-75	257.0	COG2220@1|root,arCOG00497@2157|Archaea,2XTCN@28890|Euryarchaeota,245Z6@183980|Archaeoglobi	183980|Archaeoglobi	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
LZS1_k127_1457647_1	1236689.MMALV_01920	2.483e-97	327.0	COG1571@1|root,arCOG01116@2157|Archaea,2XTUY@28890|Euryarchaeota	28890|Euryarchaeota	S	methanogenesis marker protein 11	-	-	-	-	-	-	-	-	-	-	-	-	DUF1743
LZS1_k127_1457647_0	439481.Aboo_0417	2.349e-108	356.0	COG0020@1|root,arCOG01532@2157|Archaea,2XSW1@28890|Euryarchaeota,3F2F2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.89	ko:K15888	ko00900,map00900	-	R09730	RC00279,RC02839	ko00000,ko00001,ko01000	-	-	-	Prenyltransf
LZS1_k127_1457647_7	673860.AciM339_0367	5.705e-21	95.0	COG1522@1|root,arCOG01580@2157|Archaea,2XYWZ@28890|Euryarchaeota,3F2W1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
LZS1_k127_148759_2	589924.Ferp_1803	9.105e-12	70.0	COG0375@1|root,arCOG04426@2157|Archaea,2Y0W9@28890|Euryarchaeota,24792@183980|Archaeoglobi	183980|Archaeoglobi	S	Hydrogenase nickel insertion protein HypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
LZS1_k127_148759_1	1236689.MMALV_11490	2.286e-125	411.0	COG0409@1|root,arCOG04428@2157|Archaea,2XTJA@28890|Euryarchaeota,3F2F1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
LZS1_k127_148759_0	647113.Metok_0186	5.991e-176	569.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
LZS1_k127_1492868_3	742725.HMPREF9450_01123	1.177e-10	62.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia,22UFP@171550|Rikenellaceae	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
LZS1_k127_1492868_2	1347392.CCEZ01000015_gene2772	1.372e-37	148.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,36FKV@31979|Clostridiaceae	186801|Clostridia	S	flavin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
LZS1_k127_1492868_0	237368.SCABRO_03363	1.59e-175	571.0	COG0243@1|root,COG0243@2|Bacteria,2IWWH@203682|Planctomycetes	2|Bacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
LZS1_k127_1492868_1	1121405.dsmv_2622	4.194e-94	324.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42PZ6@68525|delta/epsilon subdivisions,2WKNQ@28221|Deltaproteobacteria,2MI1H@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Amino acid kinase family	-	-	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
LZS1_k127_1504229_0	869209.Tresu_0075	2.001e-97	329.0	COG2309@1|root,COG2309@2|Bacteria,2J605@203691|Spirochaetes	203691|Spirochaetes	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
LZS1_k127_1504229_2	1278073.MYSTI_05406	6.853e-33	139.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
LZS1_k127_1504229_5	5722.XP_001313641.1	1.947e-11	73.0	COG5078@1|root,KOG0419@2759|Eukaryota	2759|Eukaryota	O	histone ubiquitination	-	GO:0000151,GO:0000209,GO:0000228,GO:0000785,GO:0000790,GO:0000792,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006325,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016043,GO:0016567,GO:0016569,GO:0016570,GO:0016574,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0031371,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0032991,GO:0033503,GO:0033554,GO:0034641,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051603,GO:0051716,GO:0061630,GO:0061659,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234	2.3.2.23	ko:K10573	ko04120,map04120	-	-	-	ko00000,ko00001,ko01000,ko03400,ko04121	-	-	-	UQ_con
LZS1_k127_1504229_4	5479.M3K0L5	6.631e-14	80.0	COG1310@1|root,KOG1554@2759|Eukaryota,38D5Q@33154|Opisthokonta,3NUK7@4751|Fungi,3QNEP@4890|Ascomycota,3RTEN@4891|Saccharomycetes,479K3@766764|Debaryomycetaceae	4751|Fungi	OT	COP9 signalosome complex subunit 5	RRI1	GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243	-	ko:K09613	-	-	-	-	ko00000,ko01000,ko01002,ko04121	-	-	-	JAB
LZS1_k127_1504229_1	439481.Aboo_0638	1.815e-48	179.0	COG0794@1|root,arCOG00068@2157|Archaea,2XX86@28890|Euryarchaeota,3F2MP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	SIS domain	-	-	5.3.1.27	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05339,R09780	RC00377	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS
LZS1_k127_1504229_3	673860.AciM339_0397	3.88e-31	125.0	COG0648@1|root,arCOG01894@2157|Archaea,2XU62@28890|Euryarchaeota,3F2J1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
LZS1_k127_1530718_3	439481.Aboo_0620	3.428e-09	66.0	arCOG02497@1|root,arCOG02497@2157|Archaea	2157|Archaea	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,NosD
LZS1_k127_1530718_2	1348583.ATLH01000018_gene2440	6.573e-14	86.0	COG3291@1|root,COG3291@2|Bacteria,4PKJH@976|Bacteroidetes,1IJAY@117743|Flavobacteriia,1FAMT@104264|Cellulophaga	976|Bacteroidetes	E	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PKD
LZS1_k127_1530718_1	1184251.TCELL_1207	1.228e-53	201.0	COG0601@1|root,arCOG00751@2157|Archaea,2XQNC@28889|Crenarchaeota	28889|Crenarchaeota	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_1530718_0	1499967.BAYZ01000132_gene306	7.083e-69	263.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS1_k127_1533179_11	1236689.MMALV_07230	7.623e-60	212.0	COG0520@1|root,arCOG00065@2157|Archaea,2XSYI@28890|Euryarchaeota	2157|Archaea	E	Cysteine desulfurase	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
LZS1_k127_1533179_1	1123288.SOV_4c01250	4.371e-149	482.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4H31K@909932|Negativicutes	909932|Negativicutes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS1_k127_1533179_12	1121430.JMLG01000021_gene1404	5.796e-58	203.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,261QI@186807|Peptococcaceae	186801|Clostridia	C	FeS cluster assembly scaffold protein NifU	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
LZS1_k127_1533179_7	439481.Aboo_0832	7.781e-103	343.0	COG0167@1|root,arCOG00603@2157|Archaea,2XTMB@28890|Euryarchaeota,3F2FC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS1_k127_1533179_10	439481.Aboo_0831	2.802e-65	234.0	COG0543@1|root,arCOG02199@2157|Archaea,2XSY9@28890|Euryarchaeota,3F2KR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
LZS1_k127_1533179_6	224719.Abm4_0181	4.594e-113	377.0	COG0119@1|root,arCOG02092@2157|Archaea,2XV8D@28890|Euryarchaeota,23PFQ@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	aksA	-	2.3.3.14	ko:K10977	ko00300,ko00620,ko00680,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00620,map00680,map01100,map01120,map01130,map01210,map01230	M00608	R00271,R08213,R08331,R08332	RC00004,RC00067,RC02149,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
LZS1_k127_1533179_14	1459636.NTE_02186	2.117e-08	61.0	COG2522@1|root,arCOG00017@2157|Archaea,41SJZ@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Transcriptional regulator	-	-	-	ko:K07108	-	-	-	-	ko00000	-	-	-	-
LZS1_k127_1533179_16	1121930.AQXG01000021_gene1675	1.877e-06	58.0	2DQS1@1|root,338C0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1533179_15	1121930.AQXG01000021_gene1675	5.412e-07	60.0	2DQS1@1|root,338C0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1533179_5	1121430.JMLG01000025_gene86	3.488e-119	392.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,260EI@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS1_k127_1533179_9	1121468.AUBR01000007_gene251	7.313e-69	241.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,42ENY@68295|Thermoanaerobacterales	186801|Clostridia	E	TIGRFAM Serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
LZS1_k127_1533179_3	1121422.AUMW01000035_gene2655	2.242e-140	462.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,2609V@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
LZS1_k127_1533179_8	1236689.MMALV_10380	4.723e-79	276.0	COG2516@1|root,arCOG00662@2157|Archaea,2XV52@28890|Euryarchaeota	28890|Euryarchaeota	S	Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS1_k127_1533179_0	1236689.MMALV_10120	7.797e-198	632.0	COG0008@1|root,arCOG04302@2157|Archaea,2XSYV@28890|Euryarchaeota,3F2HK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
LZS1_k127_1533179_4	391623.TERMP_00411	5.189e-134	439.0	COG0043@1|root,arCOG01671@2157|Archaea,2XUDW@28890|Euryarchaeota,242S6@183968|Thermococci	183968|Thermococci	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
LZS1_k127_1533179_13	351160.RCIX652	1.013e-17	87.0	COG0316@1|root,arCOG04560@2157|Archaea,2XXWU@28890|Euryarchaeota,2NA1P@224756|Methanomicrobia	224756|Methanomicrobia	O	Iron-sulphur cluster biosynthesis	-	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
LZS1_k127_1533179_2	224325.AF_1458	8.229e-144	473.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,245TM@183980|Archaeoglobi	183980|Archaeoglobi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,HHH_5,Helicase_C
LZS1_k127_1542334_2	1173028.ANKO01000190_gene426	4.59e-09	67.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria	1117|Cyanobacteria	O	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
LZS1_k127_1542334_1	439481.Aboo_0477	8.125e-28	132.0	COG0577@1|root,arCOG02312@2157|Archaea,2Y715@28890|Euryarchaeota,3F34J@33867|unclassified Euryarchaeota	28890|Euryarchaeota	P	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS1_k127_1542334_0	439481.Aboo_0478	3.096e-57	204.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,3F2R8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	ABC transporter	yvrO-2	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_1553574_1	1191523.MROS_2639	5.563e-84	289.0	COG0573@1|root,COG0573@2|Bacteria	2|Bacteria	P	inorganic phosphate transmembrane transporter activity	pstC	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	iAF987.Gmet_2702	BPD_transp_1
LZS1_k127_1553574_0	436308.Nmar_0479	1.334e-85	297.0	COG0226@1|root,arCOG00213@2157|Archaea,41SXU@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM phosphate ABC transporter	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS1_k127_1557402_3	439481.Aboo_0521	5.735e-08	55.0	COG0592@1|root,arCOG00488@2157|Archaea,2XT8B@28890|Euryarchaeota,3F2MA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication	pcn	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576	-	ko:K04802	ko03030,ko03410,ko03420,ko03430,ko04110,ko04530,ko05161,ko05166,map03030,map03410,map03420,map03430,map04110,map04530,map05161,map05166	M00295	-	-	ko00000,ko00001,ko00002,ko03032,ko03400	-	-	-	PCNA_C,PCNA_N
LZS1_k127_1557402_1	647113.Metok_0144	3.51e-27	114.0	COG1594@1|root,arCOG00579@2157|Archaea,2XY3E@28890|Euryarchaeota,23R2W@183939|Methanococci	183939|Methanococci	K	Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family	-	GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141	-	ko:K03057	ko01100,map01100	-	-	-	br01611,ko00000,ko03021	-	-	-	RNA_POL_M_15KD,TFIIS_C
LZS1_k127_1557402_2	673860.AciM339_1192	9.946e-10	70.0	arCOG03853@1|root,arCOG03853@2157|Archaea,2Y52X@28890|Euryarchaeota,3F32T@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1557402_0	747365.Thena_0014	1.865e-33	133.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,42GI7@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
LZS1_k127_1573602_1	1236689.MMALV_09970	2.226e-18	87.0	COG1591@1|root,arCOG00919@2157|Archaea,2XY2Q@28890|Euryarchaeota,3F2NJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Archaeal holliday junction resolvase (hjc)	-	-	-	-	-	-	-	-	-	-	-	-	Hjc
LZS1_k127_1573602_0	195522.BD01_0234	3.781e-49	178.0	COG0017@1|root,arCOG00406@2157|Archaea,2XTRE@28890|Euryarchaeota,242Q1@183968|Thermococci	183968|Thermococci	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K22503	ko00970,map00970	M00359	R05577	RC00055,RC00523	ko00000,ko00001,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS1_k127_1574732_1	573063.Metin_0709	1.663e-96	329.0	COG1679@1|root,arCOG04278@2157|Archaea,2XTY6@28890|Euryarchaeota,23QFZ@183939|Methanococci	183939|Methanococci	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
LZS1_k127_1574732_2	1054217.TALC_00512	1.212e-60	223.0	COG1184@1|root,COG1786@1|root,arCOG01127@2157|Archaea,arCOG04279@2157|Archaea,2XYXJ@28890|Euryarchaeota	28890|Euryarchaeota	C	Belongs to the UPF0107 family	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
LZS1_k127_1574732_0	1094980.Mpsy_0259	0.0	1064.0	COG0060@1|root,arCOG00807@2157|Archaea,2XTIX@28890|Euryarchaeota,2N9A3@224756|Methanomicrobia	224756|Methanomicrobia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
LZS1_k127_1584252_0	1054217.TALC_00160	2.569e-138	446.0	COG1222@1|root,arCOG01306@2157|Archaea	2157|Archaea	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates	pan	GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	-	ko:K03420	ko03050,map03050	M00343	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
LZS1_k127_1584252_2	439481.Aboo_1419	3.554e-29	126.0	COG1813@1|root,arCOG01863@2157|Archaea,2XXND@28890|Euryarchaeota,3F2TJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K03627	-	-	-	-	ko00000	-	-	-	HTH_3
LZS1_k127_1584252_3	797114.C475_16004	2.749e-20	96.0	COG3612@1|root,arCOG04418@2157|Archaea,2XXT8@28890|Euryarchaeota,23W4C@183963|Halobacteria	183963|Halobacteria	S	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	DUF2240
LZS1_k127_1584252_1	1054217.TALC_01481	4.909e-78	266.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,241IM@183967|Thermoplasmata	183967|Thermoplasmata	O	TCP-1/cpn60 chaperonin family	-	-	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
LZS1_k127_1587075_1	439481.Aboo_0043	7.893e-58	211.0	COG0565@1|root,arCOG01018@2157|Archaea,2XUIY@28890|Euryarchaeota,3F2NC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	TIGRFAM RNA methyltransferase, TrmH family, group 1	trmH	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
LZS1_k127_1587075_0	1293048.CBMB010000004_gene2377	3.874e-94	319.0	COG0206@1|root,arCOG02201@2157|Archaea,2XSV8@28890|Euryarchaeota,23TS5@183963|Halobacteria	183963|Halobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ2	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS1_k127_1587075_3	673860.AciM339_0078	7.009e-22	98.0	COG3609@1|root,arCOG06966@2157|Archaea,2Y5GZ@28890|Euryarchaeota,3F3D2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Ribbon-helix-helix protein, copG family	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	RHH_1
LZS1_k127_1587075_2	383372.Rcas_2277	4.69e-23	112.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
LZS1_k127_1587075_4	439481.Aboo_0971	3.474e-08	55.0	COG2101@1|root,arCOG01764@2157|Archaea,2XTTR@28890|Euryarchaeota,3F2KX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	tbp	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
LZS1_k127_1609596_0	572547.Amico_0137	8.545e-148	477.0	COG0281@1|root,COG0281@2|Bacteria,3T9QC@508458|Synergistetes	508458|Synergistetes	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
LZS1_k127_1609596_1	439481.Aboo_1286	1.719e-99	337.0	COG1031@1|root,arCOG01359@2157|Archaea,2XSVQ@28890|Euryarchaeota,3F2GV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	HHH,HHH_3,Radical_SAM
LZS1_k127_1610376_1	1236689.MMALV_00740	1.947e-18	88.0	COG0440@1|root,arCOG04445@2157|Archaea	2157|Archaea	E	Acetolactate synthase small	ilvN	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
LZS1_k127_1610376_0	1041930.Mtc_0211	3.318e-89	302.0	COG0028@1|root,arCOG01998@2157|Archaea,2XT5F@28890|Euryarchaeota,2N9B4@224756|Methanomicrobia	224756|Methanomicrobia	E	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS1_k127_1644862_2	673860.AciM339_0020	5.762e-05	51.0	COG1581@1|root,arCOG01753@2157|Archaea,2XZH4@28890|Euryarchaeota,3F3FZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
LZS1_k127_1644862_1	1094508.Tsac_1491	5.713e-72	253.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,42FCT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM PP-loop domain protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase
LZS1_k127_1644862_0	1089553.Tph_c00370	7.113e-74	263.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,42FCC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
LZS1_k127_1644862_3	1280692.AUJL01000021_gene593	7.231e-05	54.0	COG1198@1|root,COG4260@1|root,COG1198@2|Bacteria,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia	186801|Clostridia	L	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zinc_ribbon_2
LZS1_k127_1675078_6	1125863.JAFN01000001_gene2308	6.279e-09	61.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
LZS1_k127_1675078_5	1041930.Mtc_0513	1.499e-18	91.0	COG1658@1|root,arCOG01486@2157|Archaea,2Y0G2@28890|Euryarchaeota,2NA2F@224756|Methanomicrobia	224756|Methanomicrobia	L	metal ion binding	-	-	-	-	-	-	-	-	-	-	-	-	Toprim_4
LZS1_k127_1675078_1	70601.3258439	3.72e-122	406.0	COG0403@1|root,arCOG00077@2157|Archaea,2XT39@28890|Euryarchaeota,242SE@183968|Thermococci	183968|Thermococci	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS1_k127_1675078_0	1343739.PAP_02655	6.069e-176	571.0	COG1003@1|root,arCOG00076@2157|Archaea,2XT3V@28890|Euryarchaeota,242MV@183968|Thermococci	183968|Thermococci	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS1_k127_1675078_7	1120936.KB907227_gene2935	2.635e-08	58.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
LZS1_k127_1675078_3	1236689.MMALV_01370	3.255e-40	156.0	COG0125@1|root,arCOG01891@2157|Archaea,2XTAM@28890|Euryarchaeota,3F2RW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Thymidylate kinase	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS1_k127_1675078_2	1236689.MMALV_01380	4.76e-97	331.0	COG0452@1|root,arCOG01704@2157|Archaea,2XTZK@28890|Euryarchaeota,3F2J3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
LZS1_k127_1675078_4	351160.RCIX620	1.149e-24	113.0	COG1829@1|root,arCOG04263@2157|Archaea,2XST6@28890|Euryarchaeota,2N9J3@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM GHMP kinase	-	-	2.7.1.169	ko:K06982	ko00770,ko01100,map00770,map01100	-	R09378	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF692.Mbar_A3255	GHMP_kinases_N
LZS1_k127_1712617_0	1457250.BBMO01000002_gene2838	1.12e-12	77.0	arCOG02420@1|root,arCOG03991@1|root,arCOG02420@2157|Archaea,arCOG03991@2157|Archaea,2Y822@28890|Euryarchaeota	28890|Euryarchaeota	S	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Pilin_N
LZS1_k127_1730387_0	693661.Arcve_0149	5.078e-36	143.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
LZS1_k127_1730387_1	1121468.AUBR01000018_gene2711	4.266e-15	77.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia	186801|Clostridia	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS1_k127_1736689_0	1236689.MMALV_14890	1.709e-95	321.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y696@28890|Euryarchaeota,3F2WC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
LZS1_k127_1736689_1	748247.AZKH_3076	3.416e-79	273.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,2KV7R@206389|Rhodocyclales	206389|Rhodocyclales	H	dihydropteroate synthase	dhpS	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
LZS1_k127_1736689_2	351160.RCIX2	3.698e-37	160.0	COG2202@1|root,arCOG02353@1|root,arCOG02353@2157|Archaea,arCOG06515@2157|Archaea,2Y3CS@28890|Euryarchaeota,2NAS5@224756|Methanomicrobia	224756|Methanomicrobia	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_1845485_2	304371.MCP_1803	2.752e-80	275.0	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,2NAZZ@224756|Methanomicrobia	224756|Methanomicrobia	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
LZS1_k127_1845485_3	192952.MM_0475	5.907e-23	106.0	COG0517@1|root,arCOG00606@2157|Archaea,2XZ85@28890|Euryarchaeota,2N9UA@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS1_k127_1845485_0	439481.Aboo_0041	2.612e-134	437.0	COG1899@1|root,arCOG04142@2157|Archaea,2XSTD@28890|Euryarchaeota,3F2F3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue	dys	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
LZS1_k127_1845485_4	1293048.CBMB010000003_gene1126	0.0007249	51.0	arCOG00373@1|root,arCOG00373@2157|Archaea,2XT1K@28890|Euryarchaeota,23SAW@183963|Halobacteria	183963|Halobacteria	L	ATPase involved in DNA repair	sph2	-	-	-	-	-	-	-	-	-	-	-	AAA_23
LZS1_k127_1845485_1	647113.Metok_1293	1.215e-80	281.0	COG0473@1|root,arCOG01163@2157|Archaea,2XT99@28890|Euryarchaeota,23Q0Y@183939|Methanococci	183939|Methanococci	C	PFAM isocitrate isopropylmalate dehydrogenase	aksF	GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576	1.1.1.87	ko:K10978	ko00300,ko00680,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00680,map01100,map01120,map01130,map01210,map01230	M00608	R01934,R01936,R04862,R08214,R08215	RC00084,RC00114,RC00626	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS1_k127_188049_0	589924.Ferp_0388	1.733e-89	299.0	COG0059@1|root,arCOG04465@2157|Archaea,2XTGU@28890|Euryarchaeota,245PI@183980|Archaeoglobi	183980|Archaeoglobi	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
LZS1_k127_188049_1	387631.Asulf_00679	6.039e-69	243.0	COG0179@1|root,arCOG00235@2157|Archaea,2XU30@28890|Euryarchaeota,245Y2@183980|Archaeoglobi	183980|Archaeoglobi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
LZS1_k127_194887_1	471857.Svir_19890	3.866e-19	87.0	COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,4DYSP@85010|Pseudonocardiales	201174|Actinobacteria	EP	ABC-type dipeptide oligopeptide nickel transport system, permease component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS1_k127_194887_0	768706.Desor_3513	4.202e-72	255.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
LZS1_k127_1987358_1	28444.JODQ01000008_gene1195	4.285e-10	65.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria,4EGUW@85012|Streptosporangiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS1_k127_1987358_0	1121405.dsmv_2622	6.446e-95	326.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42PZ6@68525|delta/epsilon subdivisions,2WKNQ@28221|Deltaproteobacteria,2MI1H@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Amino acid kinase family	-	-	1.1.1.3,2.7.2.4	ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
LZS1_k127_2008102_3	696281.Desru_1395	0.0006389	51.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,24AKU@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator	-	-	-	ko:K08151,ko:K08153	-	M00668,M00717	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
LZS1_k127_2008102_1	439481.Aboo_0620	1.497e-19	102.0	arCOG02497@1|root,arCOG02497@2157|Archaea	2157|Archaea	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,NosD
LZS1_k127_2008102_2	1220534.B655_1297	1.987e-07	63.0	arCOG12322@1|root,arCOG12322@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2008102_0	457421.CBFG_03104	6.242e-39	155.0	COG4927@1|root,COG4927@2|Bacteria,1UEAE@1239|Firmicutes,24NBC@186801|Clostridia,26BY1@186813|unclassified Clostridiales	186801|Clostridia	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	ko:K19200	ko00311,ko01100,ko01130,map00311,map01100,map01130	-	-	-	ko00000,ko00001,ko01002	-	-	-	AAT
LZS1_k127_2040105_1	1041930.Mtc_0662	1.795e-22	102.0	COG0468@1|root,arCOG00417@2157|Archaea,2XTI2@28890|Euryarchaeota,2N9KC@224756|Methanomicrobia	224756|Methanomicrobia	L	Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange	radB	-	-	ko:K04484	-	-	-	-	ko00000,ko03400	-	-	-	Rad51
LZS1_k127_2040105_0	1236689.MMALV_14530	2.65e-44	168.0	COG0533@1|root,arCOG01185@2157|Archaea,2XT07@28890|Euryarchaeota,3F2H7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	LT	Protein kinase domain	kae1	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234,2.7.11.1	ko:K08851,ko:K15904	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko01001,ko03016	-	-	-	Kdo,Peptidase_M22,Pkinase,RIO1
LZS1_k127_2048098_1	368407.Memar_1766	2.796e-176	569.0	COG1796@1|root,arCOG00305@2157|Archaea,2XT14@28890|Euryarchaeota,2N90T@224756|Methanomicrobia	224756|Methanomicrobia	L	Helix-hairpin-helix domain	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
LZS1_k127_2048098_0	1125863.JAFN01000001_gene929	9.679e-214	683.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS1_k127_2089337_1	1142394.PSMK_18370	2.111e-23	109.0	COG4894@1|root,COG4894@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K21429	-	-	-	-	ko00000,ko01002	-	-	-	-
LZS1_k127_2089337_2	305900.GV64_16775	1.438e-08	63.0	COG4995@1|root,COG4995@2|Bacteria,1N2CY@1224|Proteobacteria,1SPW4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2089337_0	671143.DAMO_0892	3.897e-119	390.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	3.4.22.38	ko:K01371	ko04142,ko04210,ko04380,ko04620,ko05323,map04142,map04210,map04380,map04620,map05323	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_C1
LZS1_k127_2106463_0	693661.Arcve_0601	1.066e-89	306.0	COG1304@1|root,arCOG00613@2157|Archaea,2XT6H@28890|Euryarchaeota,245R4@183980|Archaeoglobi	183980|Archaeoglobi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
LZS1_k127_2107299_1	697281.Mahau_0889	3.908e-156	503.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,42FHK@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM formate-tetrahydrofolate ligase FTHFS	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
LZS1_k127_2107299_4	267377.MMP0825	4.574e-73	262.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
LZS1_k127_2107299_6	1265505.ATUG01000001_gene3026	1.133e-52	206.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
LZS1_k127_2107299_11	760568.Desku_1477	2.634e-31	127.0	COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,261V3@186807|Peptococcaceae	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
LZS1_k127_2107299_5	555088.DealDRAFT_1100	4.616e-73	252.0	COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,42KJ4@68298|Syntrophomonadaceae	186801|Clostridia	C	Methylene-tetrahydrofolate reductase C terminal	metV	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS18525	MTHFR_C
LZS1_k127_2107299_2	555088.DealDRAFT_1099	4.909e-116	387.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,42K7P@68298|Syntrophomonadaceae	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
LZS1_k127_2107299_10	1297742.A176_00599	9.313e-39	164.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,42ZIG@68525|delta/epsilon subdivisions,2WUZE@28221|Deltaproteobacteria,2YX8Y@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
LZS1_k127_2107299_3	589924.Ferp_1932	1.743e-87	302.0	COG0477@1|root,arCOG00130@2157|Archaea,2XSTP@28890|Euryarchaeota	28890|Euryarchaeota	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_2107299_0	1054217.TALC_00185	1.464e-175	565.0	COG0138@1|root,arCOG02824@2157|Archaea,2XT5P@28890|Euryarchaeota,241IY@183967|Thermoplasmata	183967|Thermoplasmata	F	AICARFT/IMPCHase bienzyme	-	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
LZS1_k127_2107299_9	673860.AciM339_0609	4.074e-44	179.0	COG0467@1|root,arCOG01178@2157|Archaea,2Y0GM@28890|Euryarchaeota,3F33E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	PFAM GvpD gas vesicle	-	-	-	-	-	-	-	-	-	-	-	-	GvpD
LZS1_k127_2107299_13	439481.Aboo_0442	1.282e-13	81.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y75A@28890|Euryarchaeota,3F3F6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2107299_8	1054217.TALC_00256	4.02e-48	184.0	COG0440@1|root,arCOG00811@2157|Archaea,2Y3B3@28890|Euryarchaeota	28890|Euryarchaeota	E	amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2107299_12	673860.AciM339_0276	1.072e-20	96.0	arCOG13537@1|root,arCOG13537@2157|Archaea,2Y1U2@28890|Euryarchaeota,3F2T4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2107299_7	1209989.TepiRe1_2813	1.834e-48	176.0	COG2403@1|root,COG2403@2|Bacteria,1TPZD@1239|Firmicutes,24E2D@186801|Clostridia,42HSE@68295|Thermoanaerobacterales	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
LZS1_k127_2117571_0	273116.14325192	8.712e-284	889.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,241IB@183967|Thermoplasmata	183967|Thermoplasmata	O	Cell division protein 48 (CDC48) domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
LZS1_k127_2117571_13	673860.AciM339_1207	2.149e-25	107.0	COG1873@1|root,arCOG02155@2157|Archaea,2Y75G@28890|Euryarchaeota,3F3FD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
LZS1_k127_2117571_5	118168.MC7420_3051	7.459e-55	219.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_2117571_14	5888.CAK59793	1.025e-17	98.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
LZS1_k127_2117571_1	439481.Aboo_1085	7.212e-174	559.0	COG1243@1|root,arCOG01361@2157|Archaea,2XT9Z@28890|Euryarchaeota,3F2HC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Radical_SAM C-terminal domain	elp3	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
LZS1_k127_2117571_19	439481.Aboo_1326	2.423e-06	54.0	arCOG05352@1|root,arCOG05352@2157|Archaea,2Y75N@28890|Euryarchaeota,3F3FP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2117571_7	1236689.MMALV_16490	1.835e-48	177.0	COG0640@1|root,arCOG05349@2157|Archaea,2XYUG@28890|Euryarchaeota,3F2RP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_5
LZS1_k127_2117571_2	368407.Memar_0849	1.056e-86	304.0	COG1116@1|root,arCOG00193@2157|Archaea,2XT97@28890|Euryarchaeota,2N9FI@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM ABC transporter related	ssuB	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
LZS1_k127_2117571_6	1236689.MMALV_07680	1.029e-49	188.0	COG0600@1|root,arCOG00169@2157|Archaea,2XUAR@28890|Euryarchaeota	28890|Euryarchaeota	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	ssuC	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
LZS1_k127_2117571_8	224325.AF_0640	2.512e-48	188.0	COG0715@1|root,arCOG01803@2157|Archaea,2Y7DP@28890|Euryarchaeota,246X9@183980|Archaeoglobi	183980|Archaeoglobi	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
LZS1_k127_2117571_9	192952.MM_1363	1.069e-45	170.0	COG4800@1|root,arCOG04375@2157|Archaea,2XXJS@28890|Euryarchaeota,2N9MB@224756|Methanomicrobia	224756|Methanomicrobia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
LZS1_k127_2117571_17	1064537.AGSO01000001_gene478	5.229e-10	69.0	COG0121@1|root,COG0121@2|Bacteria,2IBFV@201174|Actinobacteria,4FCTV@85020|Dermabacteraceae	201174|Actinobacteria	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4,GATase_6
LZS1_k127_2117571_15	865937.Gilli_2897	4.33e-13	75.0	COG1764@1|root,COG1764@2|Bacteria,4PK2K@976|Bacteroidetes,1IGG0@117743|Flavobacteriia,2P7S9@244698|Gillisia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
LZS1_k127_2117571_12	589924.Ferp_2240	5.115e-38	149.0	COG0526@1|root,arCOG01972@2157|Archaea,2XXRJ@28890|Euryarchaeota,2466S@183980|Archaeoglobi	183980|Archaeoglobi	O	PFAM Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS1_k127_2117571_16	273075.Ta0943	1.408e-11	73.0	COG1873@1|root,arCOG02155@2157|Archaea	2157|Archaea	S	PRC-barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PRC
LZS1_k127_2117571_10	673860.AciM339_1014	1.498e-45	170.0	COG0663@1|root,arCOG01849@2157|Archaea,2XXXX@28890|Euryarchaeota,3F38H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
LZS1_k127_2117571_11	273075.Ta0931	5.54e-44	166.0	COG1303@1|root,arCOG01857@2157|Archaea,2XV35@28890|Euryarchaeota,241PF@183967|Thermoplasmata	183967|Thermoplasmata	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	-	-	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	HD,Trm56
LZS1_k127_2117571_4	1236689.MMALV_16540	4.379e-62	218.0	COG1303@1|root,arCOG01857@2157|Archaea,2XV35@28890|Euryarchaeota,3F2NN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs	trm56	GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.206	ko:K07254	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Trm56
LZS1_k127_2117571_3	1054217.TALC_01532	1.762e-70	241.0	COG4860@1|root,arCOG04366@2157|Archaea,2XYAX@28890|Euryarchaeota,241R5@183967|Thermoplasmata	183967|Thermoplasmata	K	ArsR transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	ArsR
LZS1_k127_2117571_18	1459636.NTE_02126	2.568e-08	61.0	COG1599@1|root,arCOG01510@2157|Archaea,41SV1@651137|Thaumarchaeota	651137|Thaumarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	tRNA_anti-codon
LZS1_k127_2127751_3	273116.14325498	2.739e-32	132.0	COG1599@1|root,arCOG01510@2157|Archaea,2Y7BB@28890|Euryarchaeota,242B4@183967|Thermoplasmata	183967|Thermoplasmata	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	-	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
LZS1_k127_2127751_1	756499.Desde_2173	4.904e-56	220.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1TPG1@1239|Firmicutes,24C2Y@186801|Clostridia,263T4@186807|Peptococcaceae	186801|Clostridia	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
LZS1_k127_2127751_0	880072.Desac_1037	3.777e-108	366.0	COG1304@1|root,COG2221@1|root,COG1304@2|Bacteria,COG2221@2|Bacteria	2|Bacteria	C	Nitrite and sulphite reductase 4Fe-4S	yahG	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1033	DUF1116,FMN_dh,Fer4,Glu_synthase
LZS1_k127_2127751_2	1265505.ATUG01000002_gene1766	5.125e-35	143.0	COG0069@1|root,COG1143@1|root,COG0069@2|Bacteria,COG1143@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2MHXF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_synthase
LZS1_k127_2139442_0	439481.Aboo_0733	2.65e-30	130.0	COG0367@1|root,arCOG00071@2157|Archaea,2XSYP@28890|Euryarchaeota,3F3FU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_6,GATase_7
LZS1_k127_2155325_1	673860.AciM339_0885	3.405e-53	196.0	COG1402@1|root,arCOG04536@2157|Archaea,2XTQE@28890|Euryarchaeota,3F335@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS1_k127_2155325_0	439481.Aboo_0548	1.382e-67	238.0	COG0120@1|root,arCOG01122@2157|Archaea,2XTXI@28890|Euryarchaeota,3F2KZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
LZS1_k127_2155325_2	439481.Aboo_0547	1.056e-23	102.0	COG4738@1|root,arCOG04377@2157|Archaea,2XZEC@28890|Euryarchaeota,3F3DI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2158756_2	1392838.AWNM01000026_gene4419	2.564e-05	52.0	COG4927@1|root,COG4927@2|Bacteria,1NKHP@1224|Proteobacteria,2VKAB@28216|Betaproteobacteria,3T37G@506|Alcaligenaceae	28216|Betaproteobacteria	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	ko:K19200	ko00311,ko01100,ko01130,map00311,map01100,map01130	-	-	-	ko00000,ko00001,ko01002	-	-	-	AAT
LZS1_k127_2158756_1	936548.HMPREF1136_1049	5.197e-12	76.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4D5T1@85005|Actinomycetales	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS1_k127_2158756_0	439481.Aboo_1343	1.425e-114	383.0	COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota	28890|Euryarchaeota	C	aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
LZS1_k127_2171512_0	439481.Aboo_0006	8.912e-177	559.0	COG4962@1|root,arCOG01817@2157|Archaea,2XT4E@28890|Euryarchaeota,3F381@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II/IV secretion system protein	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS1_k127_2223511_2	439481.Aboo_0314	9.65e-26	109.0	COG0750@1|root,arCOG04064@2157|Archaea,2XSZP@28890|Euryarchaeota,3F2KK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
LZS1_k127_2223511_1	673860.AciM339_0272	1.083e-37	149.0	arCOG03379@1|root,arCOG03379@2157|Archaea,2XZH1@28890|Euryarchaeota,3F2PN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2223511_0	1236689.MMALV_08110	2.41e-78	274.0	COG2144@1|root,arCOG00640@2157|Archaea,2XTU9@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM AIR synthase related protein	-	-	-	ko:K07123	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
LZS1_k127_2238881_2	1304874.JAFY01000002_gene574	2.414e-62	229.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_2238881_1	1121423.JONT01000004_gene1691	2.897e-113	385.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,26042@186807|Peptococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
LZS1_k127_2238881_0	1291050.JAGE01000002_gene3526	4.606e-258	822.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
LZS1_k127_2238881_4	368407.Memar_0341	7.01e-25	109.0	COG0328@1|root,arCOG02942@2157|Archaea	2157|Archaea	L	Ribonuclease	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
LZS1_k127_2238881_3	565033.GACE_0404	2.157e-33	132.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
LZS1_k127_2247795_4	868864.Dester_0747	9.586e-37	142.0	COG0543@1|root,COG0543@2|Bacteria,2G45B@200783|Aquificae	200783|Aquificae	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
LZS1_k127_2247795_2	648996.Theam_0485	1.503e-56	206.0	COG1941@1|root,COG1941@2|Bacteria,2G44A@200783|Aquificae	200783|Aquificae	C	hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
LZS1_k127_2247795_1	529709.PYCH_08370	1e-99	341.0	COG0374@1|root,arCOG01549@2157|Archaea,2Y2IM@28890|Euryarchaeota,2434B@183968|Thermococci	183968|Thermococci	C	Nickel-dependent hydrogenase	-	-	1.12.1.3,1.12.1.5	ko:K17993	ko00920,map00920	-	R10390	-	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
LZS1_k127_2247795_7	338966.Ppro_2796	2.646e-09	64.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	-	-	3.4.23.51	ko:K00442,ko:K08315	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000,ko01002	-	-	-	HycI
LZS1_k127_2247795_0	632518.Calow_0035	8.061e-192	612.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,42F21@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
LZS1_k127_2247795_3	351160.LRC318	5.889e-38	166.0	COG2202@1|root,arCOG06515@2157|Archaea	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_2247795_8	1250232.JQNJ01000001_gene1329	9.35e-06	60.0	COG1956@1|root,COG2972@1|root,COG1956@2|Bacteria,COG2972@2|Bacteria,4NHMQ@976|Bacteroidetes,1HY6Q@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,His_kinase,Reg_prop,Y_Y_Y
LZS1_k127_2247795_5	1267535.KB906767_gene2157	3.62e-27	130.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
LZS1_k127_2247795_6	706587.Desti_3021	5.69e-12	80.0	COG2202@1|root,COG2204@1|root,COG3850@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_2307131_3	589924.Ferp_1789	0.0002229	48.0	COG1711@1|root,arCOG00551@2157|Archaea,2XYKZ@28890|Euryarchaeota,246AC@183980|Archaeoglobi	183980|Archaeoglobi	L	protein conserved in archaea	-	-	-	ko:K09723	-	-	-	-	ko00000,ko03032	-	-	-	-
LZS1_k127_2307131_2	748449.Halha_2568	3.483e-48	183.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3WAKT@53433|Halanaerobiales	186801|Clostridia	S	PFAM Metallo-beta-lactamase superfamily	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
LZS1_k127_2307131_1	1304874.JAFY01000002_gene577	1.141e-74	273.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_2307131_0	1236689.MMALV_01510	1.516e-75	261.0	COG1100@1|root,arCOG01225@2157|Archaea,2XWN4@28890|Euryarchaeota,3F2J6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	ATP_bind_1
LZS1_k127_232131_16	521045.Kole_1658	1.203e-23	104.0	COG3481@1|root,COG3481@2|Bacteria,2GC74@200918|Thermotogae	200918|Thermotogae	S	nucleic acid binding OB-fold tRNA helicase-type	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
LZS1_k127_232131_2	374847.Kcr_1249	5.519e-184	584.0	COG1350@1|root,arCOG01432@2157|Archaea	2157|Archaea	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS1_k127_232131_6	1054217.TALC_00606	9.243e-107	354.0	COG0152@1|root,arCOG04421@2157|Archaea,2XTW4@28890|Euryarchaeota,241JR@183967|Thermoplasmata	183967|Thermoplasmata	F	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
LZS1_k127_232131_4	272844.PAB2227	1.401e-138	451.0	COG1167@1|root,arCOG00492@2157|Archaea,2XVD6@28890|Euryarchaeota,243KU@183968|Thermococci	183968|Thermococci	K	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
LZS1_k127_232131_10	351160.RCIX115	3.218e-70	244.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y7MQ@28890|Euryarchaeota,2NAT0@224756|Methanomicrobia	224756|Methanomicrobia	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_232131_9	439481.Aboo_0554	4.359e-74	258.0	arCOG01172@1|root,arCOG01172@2157|Archaea,2XTWD@28890|Euryarchaeota,3F343@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	htlC	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_232131_14	264732.Moth_0735	3.714e-38	148.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,42F5V@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
LZS1_k127_232131_11	1054217.TALC_00604	2.431e-48	181.0	COG1056@1|root,arCOG00972@2157|Archaea,2XUF7@28890|Euryarchaeota,241PW@183967|Thermoplasmata	183967|Thermoplasmata	F	nicotinamide-nucleotide adenylyltransferase activity	-	-	2.7.7.1	ko:K00952	ko00760,ko01100,map00760,map01100	-	R00137,R03005	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
LZS1_k127_232131_0	673860.AciM339_1547	4.249e-253	801.0	COG0466@1|root,arCOG02160@2157|Archaea,2XTT0@28890|Euryarchaeota,3F2HW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Belongs to the peptidase S16 family	lon	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
LZS1_k127_232131_1	304371.MCP_2785	6.768e-194	628.0	COG1204@1|root,arCOG00553@2157|Archaea,2XSV4@28890|Euryarchaeota,2N9A8@224756|Methanomicrobia	224756|Methanomicrobia	L	DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks	hel308	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HHH_5,Helicase_C
LZS1_k127_232131_18	456442.Mboo_2459	1.777e-06	56.0	COG1617@1|root,arCOG02197@2157|Archaea,2XXRY@28890|Euryarchaeota,2N9VU@224756|Methanomicrobia	224756|Methanomicrobia	S	KEOPS complex Cgi121-like subunit	-	-	-	ko:K09119	-	-	-	-	ko00000,ko03016	-	-	-	CGI-121
LZS1_k127_232131_5	1499967.BAYZ01000152_gene1402	4.795e-108	357.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
LZS1_k127_232131_17	1379270.AUXF01000004_gene3007	1.154e-17	91.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,1ZT04@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
LZS1_k127_232131_15	673860.AciM339_0080	3.546e-29	138.0	COG1196@1|root,COG1361@1|root,arCOG05232@1|root,arCOG06883@1|root,arCOG00371@2157|Archaea,arCOG04400@2157|Archaea,arCOG05232@2157|Archaea,arCOG06883@2157|Archaea	2157|Archaea	S	Tubulin like	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF2334,DZR,Tubulin_2
LZS1_k127_232131_12	1121422.AUMW01000001_gene2546	6.638e-46	183.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,260PT@186807|Peptococcaceae	186801|Clostridia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS1_k127_232131_8	374847.Kcr_1128	9.47e-80	283.0	COG1530@1|root,arCOG00321@2157|Archaea	2157|Archaea	L	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS1_k127_232131_3	273068.TTE0844	1.08e-154	504.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,42FDT@68295|Thermoanaerobacterales	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
LZS1_k127_232131_13	439481.Aboo_0340	1.905e-43	162.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,3F2RZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	DUF35 OB-fold domain, acyl-CoA-associated	acaC	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
LZS1_k127_232131_7	1094980.Mpsy_1639	4.412e-80	271.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,2N94P@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM Thiolase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
LZS1_k127_2343931_4	1054217.TALC_01499	1.691e-06	53.0	COG1916@1|root,arCOG02142@2157|Archaea	2157|Archaea	S	homolog of PrgY (pheromone shutdown protein)	traB	-	-	-	-	-	-	-	-	-	-	-	TraB
LZS1_k127_2343931_2	1236689.MMALV_16250	4.638e-39	153.0	COG0560@1|root,arCOG01158@2157|Archaea	2157|Archaea	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase,Hydrolase_3
LZS1_k127_2343931_0	415426.Hbut_0632	5.531e-70	246.0	COG2518@1|root,arCOG00976@2157|Archaea,2XPYU@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS1_k127_2343931_1	673860.AciM339_0018	2.539e-41	160.0	COG1326@1|root,arCOG02680@2157|Archaea,2XUFW@28890|Euryarchaeota,3F2TD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal Zn-finger protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2343931_3	1054217.TALC_01503	5.248e-32	133.0	COG0491@1|root,arCOG00504@2157|Archaea,2Y00C@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS1_k127_2343965_5	1054217.TALC_01497	1.213e-22	99.0	COG1383@1|root,arCOG01885@2157|Archaea,2Y07I@28890|Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS17 family	rps17e	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
LZS1_k127_2343965_0	1236689.MMALV_16220	9.705e-82	290.0	COG1351@1|root,arCOG01883@2157|Archaea,2XY5D@28890|Euryarchaeota,3F2NG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
LZS1_k127_2343965_4	1054217.TALC_01499	1.08e-33	140.0	COG1916@1|root,arCOG02142@2157|Archaea	2157|Archaea	S	homolog of PrgY (pheromone shutdown protein)	traB	-	-	-	-	-	-	-	-	-	-	-	TraB
LZS1_k127_2343965_3	1236689.MMALV_16250	1.079e-40	158.0	COG0560@1|root,arCOG01158@2157|Archaea	2157|Archaea	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase,Hydrolase_3
LZS1_k127_2343965_1	415426.Hbut_0632	3.177e-71	250.0	COG2518@1|root,arCOG00976@2157|Archaea,2XPYU@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS1_k127_2343965_2	673860.AciM339_0018	4.754e-41	159.0	COG1326@1|root,arCOG02680@2157|Archaea,2XUFW@28890|Euryarchaeota,3F2TD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal Zn-finger protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2346957_0	1236689.MMALV_16610	6.348e-57	207.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y85G@28890|Euryarchaeota	28890|Euryarchaeota	C	reductase	hdrD	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
LZS1_k127_2346957_1	690850.Desaf_3320	6.483e-49	177.0	COG2033@1|root,COG2033@2|Bacteria,1QNA5@1224|Proteobacteria,435XP@68525|delta/epsilon subdivisions,2X0EC@28221|Deltaproteobacteria,2MC18@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Desulfoferrodoxin	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrodox
LZS1_k127_2346957_2	1054217.TALC_01078	2.926e-47	185.0	COG0517@1|root,arCOG00601@2157|Archaea,2XT75@28890|Euryarchaeota,241TW@183967|Thermoplasmata	183967|Thermoplasmata	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS1_k127_2351147_2	673860.AciM339_1005	5.303e-23	103.0	arCOG05517@1|root,arCOG05517@2157|Archaea,2Y72T@28890|Euryarchaeota,3F3AH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2351147_0	439481.Aboo_0654	2.304e-115	401.0	arCOG00373@1|root,arCOG02452@1|root,arCOG00373@2157|Archaea,arCOG02452@2157|Archaea,2Y71H@28890|Euryarchaeota,3F35U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_2351147_1	644281.MFS40622_0209	5.583e-103	342.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
LZS1_k127_2361559_1	693661.Arcve_0565	5.283e-43	162.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,246VP@183980|Archaeoglobi	183980|Archaeoglobi	E	pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
LZS1_k127_2361559_0	693661.Arcve_0564	1.101e-53	201.0	COG0673@1|root,arCOG01622@2157|Archaea,2XYF8@28890|Euryarchaeota	28890|Euryarchaeota	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS1_k127_2400037_1	1236689.MMALV_05600	2.024e-81	276.0	COG1709@1|root,arCOG04060@2157|Archaea,2XT58@28890|Euryarchaeota,3F2M5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07731	-	-	-	-	ko00000,ko03000	-	-	-	HTH_19,HTH_3,HTH_31
LZS1_k127_2400037_0	1236689.MMALV_05610	7.246e-159	507.0	COG3425@1|root,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,3F2GW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	hmgB	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C,HMG_CoA_synt_C,HMG_CoA_synt_N
LZS1_k127_2400037_2	351160.RCIX150	1.971e-73	251.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,2N94P@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM Thiolase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF692.Mbar_A0550	Thiolase_C,Thiolase_N
LZS1_k127_2402183_3	1137271.AZUM01000010_gene1714	1.465e-14	78.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4E04U@85010|Pseudonocardiales	201174|Actinobacteria	GL	phosphoglycerate mutase	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
LZS1_k127_2402183_2	479437.Elen_1751	7.43e-25	113.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
LZS1_k127_2402183_1	387631.Asulf_02217	4.79e-102	344.0	COG0074@1|root,arCOG01339@2157|Archaea,2XTI3@28890|Euryarchaeota,245Y5@183980|Archaeoglobi	183980|Archaeoglobi	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
LZS1_k127_2402183_0	273075.Ta1332m	4.533e-106	359.0	COG0045@1|root,arCOG01337@2157|Archaea,2XTSC@28890|Euryarchaeota,24256@183967|Thermoplasmata	183967|Thermoplasmata	C	ATP-grasp domain	-	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
LZS1_k127_2402183_4	1313301.AUGC01000018_gene761	5.773e-08	61.0	COG2823@1|root,COG2823@2|Bacteria,4NI0X@976|Bacteroidetes	976|Bacteroidetes	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2476638_8	717605.Theco_1887	6.451e-18	85.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,26QG6@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
LZS1_k127_2476638_10	487796.Flav2ADRAFT_0808	3.299e-07	59.0	COG0454@1|root,COG0456@2|Bacteria,4NQ82@976|Bacteroidetes,1I2X6@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS1_k127_2476638_1	1054217.TALC_00175	3.282e-108	379.0	COG0436@1|root,arCOG01130@2157|Archaea,2XSVT@28890|Euryarchaeota,241M6@183967|Thermoplasmata	183967|Thermoplasmata	E	Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_2476638_3	69014.TK1032	8.988e-80	293.0	COG0309@1|root,arCOG00636@2157|Archaea,2XTX2@28890|Euryarchaeota,242XP@183968|Thermococci	183968|Thermococci	O	AIR synthase related protein, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
LZS1_k127_2476638_5	246969.TAM4_1471	2.238e-46	184.0	COG1756@1|root,arCOG04122@2157|Archaea,2XX9G@28890|Euryarchaeota,243H9@183968|Thermococci	183968|Thermococci	J	Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA	nep1	GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.260	ko:K14568	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009	-	-	-	EMG1
LZS1_k127_2476638_0	1236689.MMALV_01620	1.759e-153	492.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
LZS1_k127_2476638_7	1122963.AUHB01000019_gene15	3.507e-18	95.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,36XKP@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Domain of unknown function (DUF1730)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
LZS1_k127_2476638_2	243231.GSU2744	1.075e-83	292.0	COG0477@1|root,COG0477@2|Bacteria,1QWSX@1224|Proteobacteria,43C55@68525|delta/epsilon subdivisions,2X7FI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_2476638_6	1218173.BALCAV_0215875	1.24e-23	112.0	COG0697@1|root,COG0697@2|Bacteria,1V3QH@1239|Firmicutes,4HDBZ@91061|Bacilli,1ZCM6@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_2476638_9	1033806.HTIA_2493	4.24e-10	67.0	COG1238@1|root,arCOG03118@2157|Archaea,2XWI8@28890|Euryarchaeota,23VA4@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS1_k127_2476638_4	439481.Aboo_0558	3.284e-47	175.0	arCOG13525@1|root,arCOG13525@2157|Archaea,2Y72N@28890|Euryarchaeota,3F3A7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_249008_1	1094980.Mpsy_1799	5.016e-65	240.0	COG1549@1|root,arCOG00990@2157|Archaea,2XT9W@28890|Euryarchaeota,2N990@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM PUA domain containing protein	-	-	2.6.1.97	ko:K07557	-	-	-	-	ko00000,ko01000	-	-	-	PUA,TGT,TGT_C2
LZS1_k127_249008_10	194439.CT0856	3.329e-05	51.0	COG2923@1|root,COG2923@2|Bacteria,1FF55@1090|Chlorobi	1090|Chlorobi	P	PFAM DsrE family protein	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
LZS1_k127_249008_5	419665.Maeo_0964	6.971e-30	122.0	COG1553@1|root,arCOG02068@2157|Archaea,2Y0VW@28890|Euryarchaeota	28890|Euryarchaeota	P	DsrE/DsrF-like family	-	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
LZS1_k127_249008_3	419665.Maeo_0966	3.47e-49	178.0	COG2210@1|root,arCOG02064@2157|Archaea,2XT1G@28890|Euryarchaeota	28890|Euryarchaeota	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
LZS1_k127_249008_7	419665.Maeo_0967	3.515e-25	106.0	COG0425@1|root,arCOG02062@2157|Archaea	2157|Archaea	O	redox protein regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	TusA
LZS1_k127_249008_6	1094980.Mpsy_2816	4.383e-28	117.0	COG3355@1|root,arCOG02242@2157|Archaea,2XX1H@28890|Euryarchaeota,2NB0S@224756|Methanomicrobia	224756|Methanomicrobia	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
LZS1_k127_249008_0	1236689.MMALV_12010	2.867e-120	401.0	COG0540@1|root,arCOG00911@2157|Archaea,2XSZ7@28890|Euryarchaeota,3F2F5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A1168	OTCace,OTCace_N
LZS1_k127_249008_2	1054217.TALC_01158	1.17e-53	194.0	COG1781@1|root,arCOG04229@2157|Archaea,2XWP4@28890|Euryarchaeota,241SX@183967|Thermoplasmata	183967|Thermoplasmata	F	Involved in allosteric regulation of aspartate carbamoyltransferase	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
LZS1_k127_249008_9	706587.Desti_5354	1.446e-19	92.0	COG1142@1|root,COG1142@2|Bacteria,1NY70@1224|Proteobacteria,430CN@68525|delta/epsilon subdivisions,2WVWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_249008_4	706587.Desti_5353	1.187e-41	169.0	COG2414@1|root,COG2414@2|Bacteria,1NU5A@1224|Proteobacteria,42Z6K@68525|delta/epsilon subdivisions,2WUR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_N
LZS1_k127_249008_8	1236689.MMALV_12030	8.732e-20	93.0	COG0237@1|root,arCOG01045@2157|Archaea,2XWNJ@28890|Euryarchaeota,3F2R1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	AAA domain	coaE	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A0975	AAA_17,RNA_binding
LZS1_k127_2492738_8	272844.PAB0086	1.367e-28	118.0	COG0160@1|root,arCOG00915@2157|Archaea,2XT9Y@28890|Euryarchaeota,243VN@183968|Thermococci	183968|Thermococci	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_2492738_4	555793.WSK_4000	6.602e-52	187.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4RU@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
LZS1_k127_2492738_0	1054217.TALC_00148	2.193e-194	616.0	COG0008@1|root,arCOG00402@2157|Archaea,2XSUM@28890|Euryarchaeota,241KP@183967|Thermoplasmata	183967|Thermoplasmata	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
LZS1_k127_2492738_3	673860.AciM339_0842	4.659e-77	268.0	COG0462@1|root,arCOG00067@2157|Archaea,2XTA8@28890|Euryarchaeota,3F2FN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
LZS1_k127_2492738_1	673860.AciM339_1197	3.672e-166	542.0	COG0433@1|root,arCOG00280@2157|Archaea,2Y7MA@28890|Euryarchaeota,3F30Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	AAA-like domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
LZS1_k127_2492738_7	1236689.MMALV_01400	6.373e-37	142.0	COG1849@1|root,arCOG01224@2157|Archaea,2XYS0@28890|Euryarchaeota,3F2SZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF357)	-	-	-	ko:K09728	-	-	-	-	ko00000	-	-	-	DUF357
LZS1_k127_2492738_5	351160.RCIX620	1.674e-41	170.0	COG1829@1|root,arCOG04263@2157|Archaea,2XST6@28890|Euryarchaeota,2N9J3@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM GHMP kinase	-	-	2.7.1.169	ko:K06982	ko00770,ko01100,map00770,map01100	-	R09378	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF692.Mbar_A3255	GHMP_kinases_N
LZS1_k127_2492738_2	1236689.MMALV_01380	9.122e-100	339.0	COG0452@1|root,arCOG01704@2157|Archaea,2XTZK@28890|Euryarchaeota,3F2J3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
LZS1_k127_2492738_6	1236689.MMALV_01370	1.93e-38	151.0	COG0125@1|root,arCOG01891@2157|Archaea,2XTAM@28890|Euryarchaeota,3F2RW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Thymidylate kinase	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS1_k127_2571410_0	1236689.MMALV_10940	2.52e-222	706.0	COG0423@1|root,COG0525@1|root,arCOG00405@2157|Archaea,arCOG00808@2157|Archaea,2XSXQ@28890|Euryarchaeota,3F2GU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Anticodon-binding domain of tRNA	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A1976	Anticodon_1,tRNA-synt_1
LZS1_k127_2571410_7	565033.GACE_0385	5.698e-17	85.0	COG2151@1|root,arCOG01845@2157|Archaea,2Y7ED@28890|Euryarchaeota,2475T@183980|Archaeoglobi	183980|Archaeoglobi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
LZS1_k127_2571410_2	635013.TherJR_1439	1.244e-122	408.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,2600W@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
LZS1_k127_2571410_6	410358.Mlab_1407	6.066e-26	116.0	COG0500@1|root,arCOG04989@2157|Archaea,2Y0ZS@28890|Euryarchaeota,2N9SX@224756|Methanomicrobia	224756|Methanomicrobia	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
LZS1_k127_2571410_3	1304874.JAFY01000002_gene577	1.078e-64	240.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_2571410_4	521011.Mpal_2106	5.567e-34	136.0	COG0760@1|root,arCOG07441@2157|Archaea,2Y0XR@28890|Euryarchaeota	28890|Euryarchaeota	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
LZS1_k127_2571410_8	1123252.ATZF01000010_gene457	3.982e-07	61.0	COG0697@1|root,COG0697@2|Bacteria,1VPVG@1239|Firmicutes,4HSM2@91061|Bacilli	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_2571410_1	1195236.CTER_4751	1.616e-140	456.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,3WH33@541000|Ruminococcaceae	186801|Clostridia	C	aldo keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
LZS1_k127_2571410_5	1317122.ATO12_14485	5.329e-27	112.0	COG0436@1|root,COG0436@2|Bacteria,4NSBB@976|Bacteroidetes,1IM6I@117743|Flavobacteriia,2YHQE@290174|Aquimarina	976|Bacteroidetes	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS1_k127_2590961_1	439481.Aboo_0002	5.448e-41	164.0	COG0681@1|root,arCOG01739@2157|Archaea,2Y6XH@28890|Euryarchaeota,3F2QN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Signal peptidase	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
LZS1_k127_2590961_0	439481.Aboo_0001	8.732e-42	158.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,3F2IJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in regulation of DNA replication	cdc6	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA,AAA_16,AAA_22,Cdc6_C
LZS1_k127_2591661_0	1444309.JAQG01000033_gene2906	9.62e-50	183.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4HBHX@91061|Bacilli	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	eutB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS1_k127_2591661_1	553973.CLOHYLEM_06271	0.0004016	49.0	COG4640@1|root,COG4640@2|Bacteria,1UVAE@1239|Firmicutes,2591W@186801|Clostridia,22382@1506553|Lachnoclostridium	186801|Clostridia	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2604012_4	589924.Ferp_1102	2.155e-14	74.0	COG4738@1|root,arCOG04377@2157|Archaea,2XYIC@28890|Euryarchaeota,246AV@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2604012_2	1236689.MMALV_02790	5.806e-33	130.0	COG1631@1|root,arCOG04109@2157|Archaea,2XXV3@28890|Euryarchaeota,3F2Q7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl44e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02929	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L44
LZS1_k127_2604012_3	272844.PAB7435	1.138e-16	85.0	COG2051@1|root,arCOG04108@2157|Archaea,2XZW2@28890|Euryarchaeota,244JK@183968|Thermococci	183968|Thermococci	J	ribosomal protein	rps27e	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02978	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S27e
LZS1_k127_2604012_0	1236689.MMALV_02770	2.819e-86	293.0	COG1093@1|root,arCOG04107@2157|Archaea,2XTV0@28890|Euryarchaeota,3F2GS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2a	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03237	ko03013,ko04138,ko04140,ko04141,ko04210,ko04932,ko05160,ko05162,ko05164,ko05168,map03013,map04138,map04140,map04141,map04210,map04932,map05160,map05162,map05164,map05168	-	-	-	ko00000,ko00001,ko03012	-	-	-	EIF_2_alpha,S1
LZS1_k127_2604012_5	673860.AciM339_1478	2.595e-13	70.0	COG2260@1|root,arCOG00906@2157|Archaea,2Y1HX@28890|Euryarchaeota,3F3GI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA	nop10	-	-	ko:K11130	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko03009,ko03032	-	-	-	Nop10p
LZS1_k127_2604012_1	439481.Aboo_1150	1.552e-35	137.0	COG2047@1|root,arCOG00348@2157|Archaea,2XSX4@28890|Euryarchaeota,3F2K5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PAC2 family	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
LZS1_k127_2660317_0	706587.Desti_5348	3.047e-110	368.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42R1T@68525|delta/epsilon subdivisions,2WN88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cysteine-rich domain	-	-	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
LZS1_k127_2663846_0	439481.Aboo_0763	3.042e-70	242.0	COG1491@1|root,arCOG04130@2157|Archaea,2XXAI@28890|Euryarchaeota,3F2KH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Helix-hairpin-helix motif	-	-	-	ko:K07572	-	-	-	-	ko00000	-	-	-	DUF655
LZS1_k127_2663846_2	439481.Aboo_0764	1.799e-23	103.0	COG1460@1|root,arCOG01016@2157|Archaea,2Y6FQ@28890|Euryarchaeota,3F2SK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	RNA polymerase	-	-	2.7.7.6	ko:K03051	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb4
LZS1_k127_2663846_1	1054217.TALC_01427	2.842e-27	113.0	COG2139@1|root,arCOG04129@2157|Archaea,2XXZB@28890|Euryarchaeota,241X7@183967|Thermoplasmata	183967|Thermoplasmata	J	Belongs to the eukaryotic ribosomal protein eL21 family	rpl21e	-	-	ko:K02889	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21e
LZS1_k127_2663846_3	572546.Arcpr_0709	8.414e-21	95.0	COG1258@1|root,arCOG01015@2157|Archaea,2XTTX@28890|Euryarchaeota,245ZB@183980|Archaeoglobi	183980|Archaeoglobi	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
LZS1_k127_2714938_1	673860.AciM339_0763	1.748e-86	298.0	COG1013@1|root,arCOG01601@2157|Archaea,2XT3E@28890|Euryarchaeota,3F2JH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorB	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
LZS1_k127_2714938_0	1343739.PAP_04325	5.211e-107	359.0	COG0674@1|root,arCOG01608@2157|Archaea,2XTB0@28890|Euryarchaeota,24341@183968|Thermococci	183968|Thermococci	C	oxidoreductase subunit alpha	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
LZS1_k127_2714938_2	69014.TK1982	5.542e-24	105.0	COG1144@1|root,arCOG01605@2157|Archaea,2Y02N@28890|Euryarchaeota,24454@183968|Thermococci	183968|Thermococci	C	oxidoreductase subunit delta	porD	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6
LZS1_k127_2810320_0	673860.AciM339_1562	2.223e-130	422.0	COG0466@1|root,arCOG02162@2157|Archaea,2XVMC@28890|Euryarchaeota,3F2HJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	AAA domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Mg_chelatase,Sigma54_activat
LZS1_k127_2810320_1	673860.AciM339_1247	1.284e-27	117.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0G0@28890|Euryarchaeota,3F2UC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Acetyltransferase (GNAT) domain	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
LZS1_k127_2810320_3	1197130.BAFM01000004_gene996	2.618e-05	56.0	COG3291@1|root,COG3979@1|root,arCOG07781@1|root,arCOG10187@1|root,arCOG02546@2157|Archaea,arCOG07581@2157|Archaea,arCOG07781@2157|Archaea,arCOG10187@2157|Archaea,2XVFT@28890|Euryarchaeota,23V0T@183963|Halobacteria	183963|Halobacteria	P	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C,Malectin,PKD,REJ
LZS1_k127_2810320_2	751944.HALDL1_08315	4.107e-13	81.0	COG1502@1|root,arCOG02039@2157|Archaea,2XTH3@28890|Euryarchaeota,23TAG@183963|Halobacteria	183963|Halobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	pld	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
LZS1_k127_2900195_1	572546.Arcpr_0279	4.116e-41	157.0	COG1936@1|root,arCOG01038@2157|Archaea,2XX2A@28890|Euryarchaeota,246B1@183980|Archaeoglobi	183980|Archaeoglobi	F	Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates	-	-	2.7.4.3	ko:K18532	ko00230,ko01100,ko01110,ko01130,ko03008,map00230,map01100,map01110,map01130,map03008	M00049	R00127,R01547	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	AAA_18
LZS1_k127_2900195_0	272844.PAB1701	7.533e-50	188.0	COG0101@1|root,arCOG04449@2157|Archaea,2XTH5@28890|Euryarchaeota,242SP@183968|Thermococci	183968|Thermococci	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
LZS1_k127_2927043_3	1047013.AQSP01000093_gene10	2.739e-10	66.0	arCOG12322@1|root,32UYB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2927043_2	304371.MCP_1884	8.275e-65	234.0	COG0704@1|root,arCOG00318@2157|Archaea,2XUA4@28890|Euryarchaeota,2N9P3@224756|Methanomicrobia	224756|Methanomicrobia	K	Phosphate uptake regulator, PhoU	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,PhoU
LZS1_k127_2927043_0	1459636.NTE_00046	3.822e-86	299.0	COG0226@1|root,arCOG08033@1|root,arCOG00213@2157|Archaea,arCOG08033@2157|Archaea,41SXU@651137|Thaumarchaeota	651137|Thaumarchaeota	P	TIGRFAM phosphate ABC transporter	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS1_k127_2927043_1	1191523.MROS_2639	1.587e-84	291.0	COG0573@1|root,COG0573@2|Bacteria	2|Bacteria	P	inorganic phosphate transmembrane transporter activity	pstC	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	iAF987.Gmet_2702	BPD_transp_1
LZS1_k127_2967897_2	439481.Aboo_0956	7.662e-52	190.0	COG0164@1|root,arCOG04121@2157|Archaea,2XWYC@28890|Euryarchaeota,3F2N8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS1_k127_2967897_3	1236689.MMALV_14330	2.996e-15	82.0	COG3255@1|root,arCOG01843@2157|Archaea,2Y0F9@28890|Euryarchaeota	28890|Euryarchaeota	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
LZS1_k127_2967897_0	1041930.Mtc_0552	6.497e-100	340.0	COG1208@1|root,arCOG00668@2157|Archaea,2Y87G@28890|Euryarchaeota,2N9FU@224756|Methanomicrobia	224756|Methanomicrobia	M	transferase hexapeptide repeat containing protein	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS1_k127_2967897_1	555079.Toce_1967	2.098e-93	314.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,42EKN@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
LZS1_k127_2990703_0	479434.Sthe_0223	1.8e-34	135.0	2DBJQ@1|root,32TXM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_excise
LZS1_k127_2990703_1	63737.Npun_R1490	6.141e-16	88.0	2BDP7@1|root,327CQ@2|Bacteria,1GCJ7@1117|Cyanobacteria,1HMVV@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_30437_3	589924.Ferp_0725	2.478e-72	253.0	COG0171@1|root,arCOG00069@2157|Archaea,2XT7M@28890|Euryarchaeota,24632@183980|Archaeoglobi	183980|Archaeoglobi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
LZS1_k127_30437_10	383372.Rcas_2277	1.783e-25	120.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
LZS1_k127_30437_11	429009.Adeg_2154	3.81e-21	106.0	COG2931@1|root,COG3420@1|root,COG2931@2|Bacteria,COG3420@2|Bacteria,1VTM8@1239|Firmicutes,25EQH@186801|Clostridia	186801|Clostridia	Q	hmm pf03415	cloSI	-	3.4.22.8	ko:K08587	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	Peptidase_C11
LZS1_k127_30437_12	1042877.GQS_04445	2.437e-18	90.0	COG0864@1|root,arCOG01008@2157|Archaea,2XWHW@28890|Euryarchaeota,24407@183968|Thermococci	183968|Thermococci	K	Transcriptional regulator	-	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
LZS1_k127_30437_4	304371.MCP_2619	2.607e-66	234.0	COG1387@1|root,arCOG00304@2157|Archaea,2XVZY@28890|Euryarchaeota,2N90M@224756|Methanomicrobia	224756|Methanomicrobia	E	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP
LZS1_k127_30437_8	351627.Csac_2019	4.352e-53	198.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,42F6A@68295|Thermoanaerobacterales	186801|Clostridia	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
LZS1_k127_30437_0	453591.Igni_0773	2.351e-97	329.0	COG0107@1|root,arCOG00617@2157|Archaea,2XQ5E@28889|Crenarchaeota	28889|Crenarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS1_k127_30437_7	1054217.TALC_00545	3.867e-53	199.0	COG0131@1|root,arCOG04398@2157|Archaea,2XT2K@28890|Euryarchaeota,242GZ@183967|Thermoplasmata	183967|Thermoplasmata	E	Imidazoleglycerol-phosphate dehydratase	-	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
LZS1_k127_30437_6	579137.Metvu_1014	2.566e-57	212.0	COG0106@1|root,arCOG00618@2157|Archaea,2XSUF@28890|Euryarchaeota,23QJK@183939|Methanococci	183939|Methanococci	E	TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS1_k127_30437_9	1236689.MMALV_04990	3.113e-46	186.0	COG0118@1|root,arCOG00089@2157|Archaea,2XTJ7@28890|Euryarchaeota	28890|Euryarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS1_k127_30437_5	1054217.TALC_00550	4.035e-58	220.0	COG0079@1|root,arCOG04273@2157|Archaea,2XTFZ@28890|Euryarchaeota,242D6@183967|Thermoplasmata	183967|Thermoplasmata	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_30437_1	1408419.JHYG01000011_gene2612	6.468e-93	320.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,2JPGF@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
LZS1_k127_30437_2	1144275.COCOR_03706	5.165e-79	274.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WIY9@28221|Deltaproteobacteria,2YV4H@29|Myxococcales	28221|Deltaproteobacteria	F	HisG, C-terminal domain	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
LZS1_k127_3081910_2	933262.AXAM01000035_gene2150	2.502e-09	64.0	COG0613@1|root,COG0613@2|Bacteria,1NHBC@1224|Proteobacteria,4312E@68525|delta/epsilon subdivisions,2WWDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
LZS1_k127_3081910_0	439481.Aboo_0094	4.441e-226	723.0	COG0143@1|root,arCOG00810@2157|Archaea,2XTG5@28890|Euryarchaeota,3F2F7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A0543	Anticodon_1,tRNA-synt_1g,tRNA_bind
LZS1_k127_3081910_1	351160.LRC42	5.928e-81	284.0	COG1164@1|root,arCOG04758@2157|Archaea	2157|Archaea	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
LZS1_k127_3095799_0	673860.AciM339_0572	1.391e-96	328.0	COG0404@1|root,arCOG00756@2157|Archaea,2XU1F@28890|Euryarchaeota,3F329@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
LZS1_k127_3095799_1	439481.Aboo_1433	1.859e-84	291.0	COG1363@1|root,arCOG01518@2157|Archaea,2Y8GU@28890|Euryarchaeota,3F33W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
LZS1_k127_3095799_2	1101191.KI912577_gene3021	7.633e-30	136.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TUHU@28211|Alphaproteobacteria,1JXII@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Peptidase family M28	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS1_k127_3096363_2	457570.Nther_2197	7.214e-28	121.0	COG0601@1|root,COG0601@2|Bacteria,1V0I0@1239|Firmicutes,24EVA@186801|Clostridia	2|Bacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_3096363_1	414996.IL38_15455	5.486e-35	154.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,407W5@622450|Actinopolysporales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_3096363_0	1041930.Mtc_2045	3.301e-40	159.0	COG2202@1|root,arCOG03931@1|root,arCOG03931@2157|Archaea,arCOG06515@2157|Archaea	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,GAF_2,HATPase_c,HTH_10,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phage_integrase,Response_reg
LZS1_k127_3101018_8	1151126.AQYI01000002_gene320	1.34e-27	121.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
LZS1_k127_3101018_4	477974.Daud_0854	3.101e-63	229.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia,265PC@186807|Peptococcaceae	186801|Clostridia	V	peptidase U61, LD-carboxypeptidase A	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
LZS1_k127_3101018_10	589924.Ferp_2503	1.1e-22	109.0	COG0697@1|root,arCOG00271@2157|Archaea,2XXKE@28890|Euryarchaeota,2466R@183980|Archaeoglobi	183980|Archaeoglobi	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_3101018_5	572546.Arcpr_0163	3.017e-47	175.0	COG0778@1|root,arCOG00288@2157|Archaea,2XY3A@28890|Euryarchaeota,246N7@183980|Archaeoglobi	183980|Archaeoglobi	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS1_k127_3101018_12	439481.Aboo_0449	1.089e-05	57.0	arCOG01354@1|root,arCOG01354@2157|Archaea,2Y76E@28890|Euryarchaeota,3F3GU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3101018_1	673860.AciM339_0479	3.136e-182	590.0	COG0343@1|root,COG1370@1|root,arCOG00989@2157|Archaea,arCOG00991@2157|Archaea,2XTFH@28890|Euryarchaeota,3F2F8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs	tgtA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.48	ko:K18779	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PUA,TGT,TGT_C1,TGT_C2
LZS1_k127_3101018_9	439481.Aboo_1285	5.729e-26	114.0	COG4743@1|root,arCOG02884@2157|Archaea,2Y72F@28890|Euryarchaeota,3F39B@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF1616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1616
LZS1_k127_3101018_7	673860.AciM339_1239	1.437e-37	145.0	COG1990@1|root,arCOG04228@2157|Archaea,2XYRE@28890|Euryarchaeota,3F2T0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Peptidyl-tRNA hydrolase PTH2	pth	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
LZS1_k127_3101018_6	439481.Aboo_1283	2.255e-44	173.0	COG1628@1|root,arCOG00928@2157|Archaea,2XXBV@28890|Euryarchaeota,3F36M@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Belongs to the UPF0215 family	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
LZS1_k127_3101018_2	1236689.MMALV_03240	7.625e-74	250.0	COG0048@1|root,arCOG04255@2157|Archaea,2XX4A@28890|Euryarchaeota,3F2K0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits	rps12	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
LZS1_k127_3101018_3	1236689.MMALV_03250	1.08e-68	246.0	COG0049@1|root,arCOG04254@2157|Archaea,2XTDC@28890|Euryarchaeota,3F2JI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center	rps7	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
LZS1_k127_3101018_0	673860.AciM339_0979	0.0	1021.0	COG0480@1|root,arCOG01559@2157|Archaea,2XUMQ@28890|Euryarchaeota,3F2GN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K03234	ko04152,ko04921,map04152,map04921	-	-	-	ko00000,ko00001,ko03012,ko04147	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS1_k127_3101018_11	1236689.MMALV_03270	1.13e-14	79.0	COG5256@1|root,arCOG01561@2157|Archaea,2XTNM@28890|Euryarchaeota,3F2IV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS1_k127_3142678_11	439481.Aboo_0942	3.588e-18	85.0	COG0532@1|root,arCOG01560@2157|Archaea,2XU09@28890|Euryarchaeota,3F2FJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D4,IF-2,Intein_splicing,LAGLIDADG_3
LZS1_k127_3142678_7	673860.AciM339_0274	1.059e-42	160.0	COG2125@1|root,arCOG01946@2157|Archaea,2XXZJ@28890|Euryarchaeota,3F2RJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
LZS1_k127_3142678_1	1054217.TALC_00119	7.214e-168	541.0	COG3276@1|root,arCOG01563@2157|Archaea,2XUKU@28890|Euryarchaeota,241M1@183967|Thermoplasmata	183967|Thermoplasmata	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2g	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,eIF2_C
LZS1_k127_3142678_9	439481.Aboo_1118	3.111e-20	100.0	COG1412@1|root,arCOG04312@2157|Archaea,2Y0D4@28890|Euryarchaeota,3F2SM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	Fcf1	-	-	-	ko:K07158	-	-	-	-	ko00000	-	-	-	PIN
LZS1_k127_3142678_5	1054217.TALC_00153	2.452e-78	268.0	COG1339@1|root,arCOG01904@2157|Archaea,2XTFW@28890|Euryarchaeota,241PC@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN)	ribK	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase,HTH_Crp_2
LZS1_k127_3142678_3	1054217.TALC_00152	1.073e-104	357.0	COG0047@1|root,arCOG00102@2157|Archaea,2XTPA@28890|Euryarchaeota,241Q4@183967|Thermoplasmata	183967|Thermoplasmata	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
LZS1_k127_3142678_0	1054217.TALC_00151	6.207e-275	868.0	COG0046@1|root,arCOG00641@2157|Archaea,2XU49@28890|Euryarchaeota,241M2@183967|Thermoplasmata	183967|Thermoplasmata	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS1_k127_3142678_10	1054217.TALC_00150	1.282e-19	90.0	COG1828@1|root,arCOG04462@2157|Archaea,2Y79Q@28890|Euryarchaeota,241WD@183967|Thermoplasmata	183967|Thermoplasmata	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
LZS1_k127_3142678_6	1054217.TALC_00149	1.091e-60	219.0	COG2519@1|root,arCOG00978@2157|Archaea,2XTV7@28890|Euryarchaeota,241UX@183967|Thermoplasmata	183967|Thermoplasmata	J	tRNA methyltransferase complex GCD14 subunit	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
LZS1_k127_3142678_8	604354.TSIB_1627	9.982e-30	124.0	COG0437@1|root,arCOG01500@2157|Archaea,2Y7H8@28890|Euryarchaeota,245K9@183968|Thermococci	183968|Thermococci	C	4Fe-4S dicluster domain	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4,Fer4_4
LZS1_k127_3142678_2	1121472.AQWN01000010_gene609	4.043e-164	536.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,260S3@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
LZS1_k127_3142678_12	1042877.GQS_04550	3.062e-17	87.0	COG1142@1|root,arCOG01502@2157|Archaea,2XZWR@28890|Euryarchaeota,242V3@183968|Thermococci	183968|Thermococci	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_4,Fer4_6,Fer4_9
LZS1_k127_3142678_4	234267.Acid_2435	1.166e-79	276.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_3188273_1	351160.RCIX1448	4.697e-46	170.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,2NAID@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS1_k127_3188273_0	1104324.P186_2001	2.052e-90	313.0	COG0677@1|root,arCOG00252@2157|Archaea,2XQDG@28889|Crenarchaeota	28889|Crenarchaeota	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS1_k127_3209034_2	269797.Mbar_A1819	3.245e-05	54.0	COG2512@1|root,arCOG00386@2157|Archaea	2157|Archaea	S	membrane-associated protein domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR,MarR_2,TrmB
LZS1_k127_3209034_1	351160.RCIX305	3.177e-45	169.0	COG2131@1|root,arCOG01487@2157|Archaea,2XXBC@28890|Euryarchaeota,2N9NF@224756|Methanomicrobia	224756|Methanomicrobia	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
LZS1_k127_3209034_0	269797.Mbar_A0391	9.091e-91	323.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota,2N9EB@224756|Methanomicrobia	224756|Methanomicrobia	C	Belongs to the V-ATPase 116 kDa subunit family	atpI-1	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
LZS1_k127_3209034_3	1122221.JHVI01000004_gene167	0.0007843	43.0	COG0636@1|root,COG0636@2|Bacteria,1WK69@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM ATP synthase subunit C	atpP	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
LZS1_k127_3210462_1	1104324.P186_2004	2.42e-53	194.0	COG0381@1|root,arCOG01392@2157|Archaea,2XQ7Q@28889|Crenarchaeota	28889|Crenarchaeota	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS1_k127_3210462_0	1449346.JQMO01000003_gene3366	3.204e-63	221.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS1_k127_3210515_7	439481.Aboo_0741	3.347e-17	94.0	COG1672@1|root,COG3398@1|root,arCOG02611@2157|Archaea,arCOG03166@2157|Archaea	2157|Archaea	K	ATPase, AAA superfamily	deoR2	-	3.6.4.12,4.2.3.1,6.3.4.15	ko:K01733,ko:K02039,ko:K03436,ko:K03524,ko:K03655	ko00260,ko00750,ko00780,ko01100,ko01110,ko01120,ko01230,ko03440,map00260,map00750,map00780,map01100,map01110,map01120,map01230,map03440	M00018	R01074,R01466,R05086,R05145	RC00017,RC00043,RC00070,RC00096,RC00526,RC02896	ko00000,ko00001,ko00002,ko01000,ko03000,ko03400	-	-	-	BPL_C,BPL_LplA_LipB,DeoRC,HTH_11,HTH_24,HTH_DeoR,MarR_2,PhoU
LZS1_k127_3210515_4	415426.Hbut_0268	5.458e-48	189.0	COG0477@1|root,arCOG00130@2157|Archaea,2XRIJ@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_3210515_6	420247.Msm_0102	5.295e-22	107.0	COG0620@1|root,arCOG01876@2157|Archaea,2XUCW@28890|Euryarchaeota,23NXX@183925|Methanobacteria	183925|Methanobacteria	E	Methionine synthase	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
LZS1_k127_3210515_2	673860.AciM339_0822	4.129e-59	215.0	COG1650@1|root,arCOG01616@2157|Archaea,2XUM0@28890|Euryarchaeota,3F2M2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo	dtdA	-	3.1.1.96	ko:K09716	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_deacylase
LZS1_k127_3210515_3	1236689.MMALV_13920	1.925e-51	190.0	COG0528@1|root,arCOG00858@2157|Archaea,2XT3U@28890|Euryarchaeota,3F2Q5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iAF692.Mbar_A0788	AA_kinase
LZS1_k127_3210515_1	673860.AciM339_1206	8.025e-153	496.0	COG1503@1|root,arCOG01742@2157|Archaea,2XSV5@28890|Euryarchaeota,3F2IF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA	prf1	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_1,eRF1_2,eRF1_3
LZS1_k127_3210515_0	1236689.MMALV_13900	6.005e-169	548.0	COG0018@1|root,arCOG00487@2157|Archaea,2XTWP@28890|Euryarchaeota,3F2FF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
LZS1_k127_3210515_5	592015.HMPREF1705_00648	1.416e-42	165.0	COG0095@1|root,COG0095@2|Bacteria,3TBDG@508458|Synergistetes	508458|Synergistetes	H	PFAM Biotin lipoate A B protein ligase family	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
LZS1_k127_3215981_0	69014.TK1491	4.359e-35	141.0	COG1522@1|root,arCOG01580@2157|Archaea,2XWJA@28890|Euryarchaeota,243ZM@183968|Thermococci	183968|Thermococci	K	transcription regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
LZS1_k127_3215981_1	604354.TSIB_0104	6.329e-08	65.0	arCOG03799@1|root,arCOG03799@2157|Archaea,2Y3QV@28890|Euryarchaeota,244E7@183968|Thermococci	183968|Thermococci	T	Protein of unknown function (DUF835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF835
LZS1_k127_3215981_2	7029.ACYPI002728-PA	1.773e-06	55.0	KOG4441@1|root,KOG4441@2759|Eukaryota,38FPI@33154|Opisthokonta,3BB3K@33208|Metazoa,3CS4P@33213|Bilateria,41VFR@6656|Arthropoda,3SHMR@50557|Insecta	33208|Metazoa	T	BTB And C-terminal Kelch	KLHL3	GO:0000003,GO:0000151,GO:0000209,GO:0001655,GO:0001725,GO:0001822,GO:0002009,GO:0003006,GO:0003008,GO:0003014,GO:0003096,GO:0003674,GO:0003779,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006996,GO:0007010,GO:0007049,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007293,GO:0007300,GO:0007301,GO:0007349,GO:0008092,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0015629,GO:0015672,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030001,GO:0030027,GO:0030029,GO:0030036,GO:0030154,GO:0030163,GO:0030717,GO:0030723,GO:0030725,GO:0031252,GO:0031461,GO:0031463,GO:0032432,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0035183,GO:0035239,GO:0035295,GO:0035324,GO:0036211,GO:0042592,GO:0042641,GO:0042802,GO:0042803,GO:0042995,GO:0043062,GO:0043063,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045171,GO:0045172,GO:0045478,GO:0046983,GO:0048468,GO:0048477,GO:0048513,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051276,GO:0051321,GO:0051603,GO:0051704,GO:0060429,GO:0060562,GO:0060993,GO:0061326,GO:0061333,GO:0061982,GO:0061988,GO:0065007,GO:0065008,GO:0070192,GO:0070293,GO:0070294,GO:0070647,GO:0070936,GO:0071704,GO:0071840,GO:0072001,GO:0072006,GO:0072009,GO:0072017,GO:0072028,GO:0072073,GO:0072078,GO:0072080,GO:0072088,GO:0072156,GO:0097517,GO:0120025,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1903046,GO:1990234	-	ko:K10443,ko:K10457	-	-	-	-	ko00000,ko04121	-	-	-	BACK,BTB,Kelch_1
LZS1_k127_322022_1	565033.GACE_0922	1.204e-16	79.0	COG0065@1|root,arCOG01698@2157|Archaea,2XTWH@28890|Euryarchaeota,245PP@183980|Archaeoglobi	183980|Archaeoglobi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
LZS1_k127_322022_0	868131.MSWAN_2313	4.076e-47	174.0	COG0066@1|root,arCOG02230@2157|Archaea,2XTXJ@28890|Euryarchaeota,23P24@183925|Methanobacteria	183925|Methanobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
LZS1_k127_322022_2	673860.AciM339_0019	1.18e-13	85.0	COG0457@1|root,arCOG02493@1|root,arCOG02493@2157|Archaea,arCOG03038@2157|Archaea	2157|Archaea	KLT	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	HTH_24,PQQ_2,PQQ_3,TPR_12,TPR_16,TPR_2,TPR_8
LZS1_k127_3245927_4	1459636.NTE_03059	9.667e-16	78.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3245927_1	439481.Aboo_0319	4.05e-107	363.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,3F326@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	CoA binding domain	acdA	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
LZS1_k127_3245927_5	1469607.KK073768_gene2976	3.949e-13	78.0	COG0517@1|root,COG0517@2|Bacteria,1G08K@1117|Cyanobacteria,1HKQI@1161|Nostocales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CP12
LZS1_k127_3245927_6	98439.AJLL01000035_gene2595	6.952e-13	75.0	COG0517@1|root,COG0517@2|Bacteria,1G08K@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CP12
LZS1_k127_3245927_0	1094980.Mpsy_2940	1.071e-112	385.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,2N9AI@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA-2	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_17,Fer4_7,Fer4_9,Pyr_redox_2
LZS1_k127_3245927_3	335543.Sfum_2148	4.009e-38	162.0	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,437PD@68525|delta/epsilon subdivisions,2X2XQ@28221|Deltaproteobacteria,2MRT7@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase, delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
LZS1_k127_3245927_2	335543.Sfum_1176	2.322e-103	356.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MR23@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
LZS1_k127_3245927_7	374847.Kcr_0256	2.145e-06	53.0	COG1748@1|root,arCOG00243@2157|Archaea	2157|Archaea	E	Saccharopine dehydrogenase	-	-	1.4.1.18,1.5.1.7	ko:K00290,ko:K19064	ko00300,ko00310,ko00960,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map00960,map01100,map01110,map01130,map01230	M00030,M00032	R00446,R00715,R02317	RC00062,RC00217,RC00694,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
LZS1_k127_3251111_0	1054217.TALC_01148	5.067e-101	339.0	COG0585@1|root,arCOG04252@2157|Archaea,2XUTK@28890|Euryarchaeota,241NZ@183967|Thermoplasmata	183967|Thermoplasmata	J	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
LZS1_k127_3251111_1	1125863.JAFN01000001_gene418	9.856e-80	284.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42N1X@68525|delta/epsilon subdivisions,2WKMS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase MttB (TMA methyltransferase)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
LZS1_k127_3251111_3	1094980.Mpsy_2661	1.94e-08	59.0	arCOG06113@1|root,arCOG06113@2157|Archaea,2Y130@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3251111_2	420247.Msm_0354	3.644e-17	83.0	COG1222@1|root,arCOG01306@2157|Archaea,2XTB6@28890|Euryarchaeota,23NMD@183925|Methanobacteria	183925|Methanobacteria	O	ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates	pan	-	-	ko:K03420	ko03050,map03050	M00343	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA
LZS1_k127_333422_0	479434.Sthe_3319	3.488e-19	101.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	blaB	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
LZS1_k127_333422_1	1304874.JAFY01000005_gene1226	1.539e-16	89.0	COG0546@1|root,COG0546@2|Bacteria,3TB2X@508458|Synergistetes	508458|Synergistetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS1_k127_333422_2	272844.PAB1671	9.199e-13	77.0	COG1633@1|root,arCOG03797@1|root,arCOG01104@2157|Archaea,arCOG03797@2157|Archaea,2Y37B@28890|Euryarchaeota,245EW@183968|Thermococci	183968|Thermococci	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	DUF835,Rubrerythrin
LZS1_k127_333422_3	673860.AciM339_1357	1.16e-12	78.0	COG0642@1|root,COG2202@1|root,arCOG02338@1|root,arCOG02348@1|root,arCOG02367@1|root,arCOG02334@2157|Archaea,arCOG02338@2157|Archaea,arCOG02348@2157|Archaea,arCOG02367@2157|Archaea,arCOG06408@2157|Archaea,2Y7PA@28890|Euryarchaeota	28890|Euryarchaeota	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9
LZS1_k127_3340226_0	204669.Acid345_1534	2.725e-126	416.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria,2JIZJ@204432|Acidobacteriia	57723|Acidobacteria	E	Aminotransferase class-III	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_3340226_1	439481.Aboo_0790	7.573e-50	188.0	COG1938@1|root,arCOG00347@2157|Archaea,2XT93@28890|Euryarchaeota,3F2T7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
LZS1_k127_3346620_0	448385.sce0759	6.476e-103	352.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2X24A@28221|Deltaproteobacteria,2Z1T0@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS1_k127_3359945_1	868131.MSWAN_2313	1.87e-45	169.0	COG0066@1|root,arCOG02230@2157|Archaea,2XTXJ@28890|Euryarchaeota,23P24@183925|Methanobacteria	183925|Methanobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
LZS1_k127_3359945_0	429009.Adeg_1100	9.982e-120	398.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,42FQ2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
LZS1_k127_3384769_3	673860.AciM339_1526	2.492e-28	127.0	COG3815@1|root,arCOG03949@2157|Archaea,2Y6YC@28890|Euryarchaeota,3F307@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
LZS1_k127_3384769_0	673860.AciM339_1253	1.398e-91	309.0	COG1355@1|root,arCOG01728@2157|Archaea,2XVYU@28890|Euryarchaeota,3F2NT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Belongs to the MEMO1 family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
LZS1_k127_3384769_4	268739.Nmlp_2649	3.011e-22	106.0	arCOG04041@1|root,arCOG04518@1|root,arCOG04518@2157|Archaea,arCOG07592@2157|Archaea,2Y8F4@28890|Euryarchaeota,241A5@183963|Halobacteria	183963|Halobacteria	S	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3384769_5	543526.Htur_5235	4.737e-20	101.0	arCOG04518@1|root,arCOG04518@2157|Archaea,2XUD7@28890|Euryarchaeota,23SZS@183963|Halobacteria	183963|Halobacteria	K	Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
LZS1_k127_3384769_1	1054217.TALC_00169	1.201e-88	296.0	COG0052@1|root,arCOG04245@2157|Archaea,2XTHM@28890|Euryarchaeota,241MQ@183967|Thermoplasmata	183967|Thermoplasmata	J	Belongs to the universal ribosomal protein uS2 family	rps2	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
LZS1_k127_3384769_6	439481.Aboo_0929	1.926e-16	80.0	COG1758@1|root,arCOG01268@2157|Archaea,2XZSW@28890|Euryarchaeota,3F2TZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoK	-	2.7.7.6	ko:K03055	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb6
LZS1_k127_3384769_2	410359.Pcal_0510	6.193e-34	143.0	COG0160@1|root,arCOG00915@2157|Archaea,2XPMC@28889|Crenarchaeota	28889|Crenarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_3388272_4	1379698.RBG1_1C00001G0071	3.364e-83	293.0	COG0475@1|root,COG0475@2|Bacteria	2|Bacteria	P	glutathione-regulated potassium exporter activity	kefB	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,PTS_EIIA_2
LZS1_k127_3388272_6	439481.Aboo_1535	3.928e-61	219.0	COG1378@1|root,arCOG02038@2157|Archaea,2Y7FZ@28890|Euryarchaeota,3F2ZR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Archaeal transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
LZS1_k127_3388272_0	1236689.MMALV_03570	2.798e-172	555.0	COG1964@1|root,arCOG00933@2157|Archaea,2XTMK@28890|Euryarchaeota,3F2FE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	4Fe-4S single cluster domain	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Intein_splicing,LAGLIDADG_3,Radical_SAM
LZS1_k127_3388272_10	1054217.TALC_00434	5.034e-17	84.0	COG1145@1|root,arCOG02460@2157|Archaea	2157|Archaea	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIL
LZS1_k127_3388272_2	439481.Aboo_0578	6.877e-116	385.0	COG0644@1|root,arCOG00570@2157|Archaea,2XU3J@28890|Euryarchaeota,3F2EW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	bchP	-	1.3.1.101,1.3.7.11,1.5.5.1	ko:K00311,ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored,Lycopene_cycl,Trp_halogenase
LZS1_k127_3388272_12	221288.JH992901_gene1499	3.652e-09	69.0	COG1807@1|root,COG1807@2|Bacteria,1G3HP@1117|Cyanobacteria,1JICK@1189|Stigonemataceae	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_3388272_5	342949.PNA2_0574	1.689e-76	277.0	COG0463@1|root,arCOG00894@2157|Archaea,2XWXA@28890|Euryarchaeota,242RY@183968|Thermococci	183968|Thermococci	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
LZS1_k127_3388272_7	1235797.C816_01384	2.686e-47	184.0	COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,249NS@186801|Clostridia,2N68F@216572|Oscillospiraceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	2.4.1.208	ko:K13677	ko00561,ko01100,map00561,map01100	-	R05164	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS1_k127_3388272_13	415426.Hbut_1365	2.238e-05	53.0	COG2510@1|root,arCOG03427@2157|Archaea	2157|Archaea	S	membrane	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
LZS1_k127_3388272_1	1089553.Tph_c20450	5.089e-125	413.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS1_k127_3388272_9	673860.AciM339_0356	1.13e-29	135.0	COG2244@1|root,arCOG02209@2157|Archaea,2XZR0@28890|Euryarchaeota,3F33X@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
LZS1_k127_3388272_3	439481.Aboo_0426	2.277e-110	368.0	COG0436@1|root,arCOG01130@2157|Archaea,2XSVT@28890|Euryarchaeota,3F2HI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	PFAM Aminotransferase class I and II	aspC2	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_3388272_11	319224.Sputcn32_3393	8.57e-10	65.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,1RPU5@1236|Gammaproteobacteria,2QAIQ@267890|Shewanellaceae	1236|Gammaproteobacteria	P	TRAP C4-dicarboxylate transport system permease DctM subunit	sdcS	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0034220,GO:0044425,GO:0051179,GO:0051234,GO:0055085,GO:0098656	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS1_k127_339910_1	1236689.MMALV_10940	1.475e-123	400.0	COG0423@1|root,COG0525@1|root,arCOG00405@2157|Archaea,arCOG00808@2157|Archaea,2XSXQ@28890|Euryarchaeota,3F2GU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Anticodon-binding domain of tRNA	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A1976	Anticodon_1,tRNA-synt_1
LZS1_k127_339910_2	865861.AZSU01000002_gene2618	1.423e-73	264.0	COG0863@1|root,COG0863@2|Bacteria,1TPR7@1239|Firmicutes,24A3P@186801|Clostridia,36E8V@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
LZS1_k127_339910_0	1236689.MMALV_10920	1.047e-192	617.0	COG0423@1|root,arCOG00405@2157|Archaea,2XSZK@28890|Euryarchaeota,3F2HZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Anticodon binding domain	glyS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
LZS1_k127_339910_3	673860.AciM339_0330	5.729e-32	126.0	COG0517@1|root,arCOG00600@2157|Archaea,2XU4J@28890|Euryarchaeota,3F2PE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Domain in cystathionine beta-synthase and other proteins.	cbs2	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS1_k127_3401946_2	1236689.MMALV_00580	1.15e-37	151.0	COG0438@1|root,arCOG01407@2157|Archaea	2157|Archaea	M	COG0438 Glycosyltransferase	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS1_k127_3401946_0	269797.Mbar_A3501	8.583e-102	347.0	COG0351@1|root,arCOG00020@2157|Archaea,2XSW8@28890|Euryarchaeota,2N9G9@224756|Methanomicrobia	224756|Methanomicrobia	H	PFAM Phosphomethylpyrimidine kinase type-1	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin,ThiP_synth
LZS1_k127_3401946_3	439481.Aboo_1307	6.374e-23	104.0	arCOG05357@1|root,arCOG05357@2157|Archaea,2Y1B1@28890|Euryarchaeota,3F2VN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3401946_1	386456.JQKN01000005_gene512	9.038e-85	293.0	COG1139@1|root,arCOG00335@2157|Archaea,2Y85J@28890|Euryarchaeota,23PHX@183925|Methanobacteria	183925|Methanobacteria	C	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	Fer4_8,LUD_dom
LZS1_k127_3490630_0	383372.Rcas_2277	2e-24	115.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
LZS1_k127_3506520_0	351160.RCIX2263	2.41e-117	387.0	COG0426@1|root,arCOG00509@2157|Archaea,2XSUD@28890|Euryarchaeota,2N90R@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
LZS1_k127_3520414_2	909943.HIMB100_00013810	1.205e-13	80.0	COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2TTCK@28211|Alphaproteobacteria,4BQ4N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn_helix ASNC type	lrp	GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
LZS1_k127_3520414_0	1121423.JONT01000006_gene2435	4.862e-60	220.0	COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,24DN8@186801|Clostridia,261B5@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_3520414_1	273075.Ta1106	5.604e-36	142.0	COG2150@1|root,arCOG02316@2157|Archaea,2XWH9@28890|Euryarchaeota,241VB@183967|Thermoplasmata	183967|Thermoplasmata	S	regulator of amino acid metabolism, contains ACT domain	-	-	-	ko:K07103	-	-	-	-	ko00000	-	-	-	ACT
LZS1_k127_3531650_0	1236689.MMALV_14260	1.582e-126	412.0	COG0087@1|root,arCOG04070@2157|Archaea,2XT9B@28890|Euryarchaeota,3F2H1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl3	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
LZS1_k127_3531650_2	1236689.MMALV_14250	2.59e-79	273.0	COG0469@1|root,arCOG04071@2157|Archaea,2XTXX@28890|Euryarchaeota,3F2K6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Forms part of the polypeptide exit tunnel	rpl4	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02930	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
LZS1_k127_3531650_16	1054217.TALC_01333	1.137e-30	123.0	COG0089@1|root,arCOG04072@2157|Archaea,2XYPG@28890|Euryarchaeota,241X4@183967|Thermoplasmata	183967|Thermoplasmata	J	Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome	rpl23	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
LZS1_k127_3531650_3	673860.AciM339_1101	1.145e-66	234.0	COG0090@1|root,arCOG04067@2157|Archaea,2XTCS@28890|Euryarchaeota,3F2KT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal Proteins L2, C-terminal domain	rpl2	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
LZS1_k127_3531650_7	1236689.MMALV_14220	9.375e-56	202.0	COG0185@1|root,arCOG04099@2157|Archaea,2XWI9@28890|Euryarchaeota,3F2NY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rps19p	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
LZS1_k127_3531650_15	593117.TGAM_1998	5.923e-37	144.0	COG0091@1|root,arCOG04098@2157|Archaea,2XWGN@28890|Euryarchaeota,243D0@183968|Thermococci	183968|Thermococci	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rpl22	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
LZS1_k127_3531650_1	1236689.MMALV_14200	6.979e-85	292.0	COG0092@1|root,arCOG04097@2157|Archaea,2XTHR@28890|Euryarchaeota,3F2JC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein S3	rps3	GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
LZS1_k127_3531650_21	1236689.MMALV_14190	6.146e-15	78.0	COG0255@1|root,arCOG00785@2157|Archaea,2Y1DQ@28890|Euryarchaeota,3F2VT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal L29 protein	rpl29	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
LZS1_k127_3531650_14	1236689.MMALV_14180	2.879e-38	153.0	COG0023@1|root,arCOG04223@2157|Archaea,2XXW5@28890|Euryarchaeota,3F2TV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Translation initiation factor SUI1	tif1a	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
LZS1_k127_3531650_20	339860.Msp_0900	2.951e-15	79.0	COG1588@1|root,arCOG00784@2157|Archaea,2Y0EN@28890|Euryarchaeota,23PQP@183925|Methanobacteria	183925|Methanobacteria	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp1	-	3.1.26.5	ko:K03538	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03016,ko03029	-	-	-	UPF0086
LZS1_k127_3531650_13	673860.AciM339_1107	1.047e-38	147.0	COG0186@1|root,arCOG04096@2157|Archaea,2XYPE@28890|Euryarchaeota,3F2Q9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rps17	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
LZS1_k127_3531650_8	673860.AciM339_1108	1.842e-55	199.0	COG0093@1|root,arCOG04095@2157|Archaea,2XWM6@28890|Euryarchaeota,3F2NF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rpl14	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
LZS1_k127_3531650_17	1184251.TCELL_0337	9.71e-25	108.0	COG0198@1|root,arCOG04094@2157|Archaea,2XQQB@28889|Crenarchaeota	28889|Crenarchaeota	J	Located at the polypeptide exit tunnel on the outside of the subunit	rpl24	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,Ribosomal_L26
LZS1_k127_3531650_4	439481.Aboo_1509	6.579e-61	223.0	COG1471@1|root,arCOG04093@2157|Archaea,2XT03@28890|Euryarchaeota,3F2KF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal family S4e	rps4e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02987	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	RS4NT,Ribosomal_S4e,S4
LZS1_k127_3531650_5	1054217.TALC_01321	2.654e-58	211.0	COG0094@1|root,arCOG04092@2157|Archaea,2XTRN@28890|Euryarchaeota,241QF@183967|Thermoplasmata	183967|Thermoplasmata	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rpl5	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
LZS1_k127_3531650_19	1236689.MMALV_14120	1.357e-18	88.0	COG0199@1|root,arCOG00782@2157|Archaea,2Y68V@28890|Euryarchaeota,3F2V3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein S14	rps14	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
LZS1_k127_3531650_9	1054217.TALC_01319	1.926e-53	190.0	COG0096@1|root,arCOG04091@2157|Archaea,2XWMU@28890|Euryarchaeota,241Q9@183967|Thermoplasmata	183967|Thermoplasmata	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rps8	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
LZS1_k127_3531650_6	673860.AciM339_1114	1.934e-56	203.0	COG0097@1|root,arCOG04090@2157|Archaea,2XTIS@28890|Euryarchaeota,3F2ND@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rpl6	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
LZS1_k127_3531650_10	1236689.MMALV_14090	7.854e-48	181.0	COG1717@1|root,arCOG00781@2157|Archaea,2XSZ4@28890|Euryarchaeota,3F2PV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL32 family	rpl32e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02912	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L32e
LZS1_k127_3531650_11	673860.AciM339_1116	6.126e-46	177.0	COG2147@1|root,arCOG04089@2157|Archaea,2XWU1@28890|Euryarchaeota,3F2Q2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl19e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02885	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19e
LZS1_k127_3531650_12	439481.Aboo_1502	6.522e-46	179.0	COG0256@1|root,arCOG04088@2157|Archaea,2XTWT@28890|Euryarchaeota,3F2QM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rpl18	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18_c,Ribosomal_L5e
LZS1_k127_3531650_18	1236689.MMALV_14060	1.094e-21	94.0	COG0098@1|root,arCOG04087@2157|Archaea,2XUQU@28890|Euryarchaeota,3F2HF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S12 plays an important role in translational accuracy	rps5	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
LZS1_k127_3568222_1	439481.Aboo_0538	6.26e-143	463.0	COG0012@1|root,arCOG00357@2157|Archaea,2XTZG@28890|Euryarchaeota,3F2GD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	GTPase of unknown function C-terminal	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,MMR_HSR1_C,TGS
LZS1_k127_3568222_0	673860.AciM339_1269	1.677e-259	837.0	COG0417@1|root,arCOG00328@2157|Archaea,2XU1K@28890|Euryarchaeota,3F2F0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DNA polymerase type-B family	polB1	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B,DNA_pol_B_exo1,Intein_splicing
LZS1_k127_3568222_2	269797.Mbar_A1077	5.348e-47	177.0	COG1237@1|root,arCOG00503@2157|Archaea,2XXGE@28890|Euryarchaeota,2N9XT@224756|Methanomicrobia	224756|Methanomicrobia	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
LZS1_k127_3568222_3	439481.Aboo_0933	3.724e-26	111.0	COG1342@1|root,arCOG02238@2157|Archaea,2Y002@28890|Euryarchaeota,3F3DN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Homeodomain-like domain	-	-	-	ko:K06933	-	-	-	-	ko00000	-	-	-	DUF134
LZS1_k127_3592027_0	1236689.MMALV_00150	4.868e-135	446.0	COG1311@1|root,arCOG04455@2157|Archaea,2XSUG@28890|Euryarchaeota,3F2GQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B,Metallophos
LZS1_k127_3592027_1	1121428.DESHY_40056___1	2.424e-100	340.0	COG1042@1|root,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,260BP@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
LZS1_k127_3598611_0	673860.AciM339_0481	3.903e-47	171.0	COG1095@1|root,arCOG00675@2157|Archaea,2XT6U@28890|Euryarchaeota,3F2MN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397	rpoE1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03049	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	S1,SHS2_Rpb7-N
LZS1_k127_3598611_3	1236689.MMALV_04380	4.339e-19	92.0	COG2093@1|root,arCOG04077@2157|Archaea,2Y6YF@28890|Euryarchaeota,3F2W7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Transcription elongation factor Spt4	spt4	-	2.7.7.6	ko:K03050	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Spt4
LZS1_k127_3598611_1	1230457.C476_06677	1.394e-27	118.0	COG1909@1|root,arCOG04076@2157|Archaea,2XXSG@28890|Euryarchaeota,23W2W@183963|Halobacteria	183963|Halobacteria	S	Belongs to the UPF0218 family	-	-	-	ko:K09735	-	-	-	-	ko00000	-	-	-	DUF359
LZS1_k127_3598611_2	439481.Aboo_0565	3.577e-19	91.0	COG2004@1|root,arCOG04182@2157|Archaea,2Y6EY@28890|Euryarchaeota,3F2VW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS24 family	rps24e	-	-	ko:K02974	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S24e
LZS1_k127_3598611_4	1236689.MMALV_04410	5.184e-19	88.0	COG1998@1|root,arCOG04183@2157|Archaea,2XZZ0@28890|Euryarchaeota,3F2VM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS31 family	rps27ae	-	-	ko:K02977	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04147	-	-	-	Ribosomal_S27
LZS1_k127_3598611_5	761193.Runsl_4746	3.07e-13	80.0	COG0697@1|root,COG0697@2|Bacteria,4NHBC@976|Bacteroidetes,47NYN@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_3604208_9	292459.STH2639	2.484e-26	109.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS1_k127_3604208_6	292459.STH2640	3.558e-71	248.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia	186801|Clostridia	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
LZS1_k127_3604208_5	1198452.Jab_2c34270	3.177e-71	250.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VMB3@28216|Betaproteobacteria,4779T@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS1_k127_3604208_8	552811.Dehly_1300	8.8e-39	152.0	COG0655@1|root,COG0655@2|Bacteria,2GAKP@200795|Chloroflexi,34CPA@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
LZS1_k127_3604208_2	1041930.Mtc_0346	1.14e-96	329.0	COG2309@1|root,arCOG01888@2157|Archaea,2XSUA@28890|Euryarchaeota	28890|Euryarchaeota	E	Leucyl aminopeptidase (Aminopeptidase T)	pepB2	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
LZS1_k127_3604208_13	1120998.AUFC01000016_gene45	4.14e-09	64.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C,DUF3795
LZS1_k127_3604208_12	1265505.ATUG01000001_gene2926	1.042e-12	80.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg,dCache_2
LZS1_k127_3604208_10	1395513.P343_00530	9.754e-18	89.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,4HKA1@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS1_k127_3604208_3	1123023.JIAI01000003_gene2713	1.808e-76	279.0	COG0714@1|root,COG2304@1|root,COG0714@2|Bacteria,COG2304@2|Bacteria,2GMBP@201174|Actinobacteria,4E0V2@85010|Pseudonocardiales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,VWA_CoxE
LZS1_k127_3604208_4	945713.IALB_1115	6.442e-75	259.0	COG1945@1|root,COG1945@2|Bacteria	2|Bacteria	I	arginine decarboxylase activity	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
LZS1_k127_3604208_1	880072.Desac_0724	1.4e-109	365.0	COG1899@1|root,COG1899@2|Bacteria,1MVC6@1224|Proteobacteria,43B4N@68525|delta/epsilon subdivisions,2X6IA@28221|Deltaproteobacteria,2MSF8@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
LZS1_k127_3604208_0	1056495.Calag_0699	2.727e-113	381.0	COG0160@1|root,arCOG00915@2157|Archaea,2XPMC@28889|Crenarchaeota	28889|Crenarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_3604208_11	1408422.JHYF01000003_gene819	8.323e-16	83.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia,36KWH@31979|Clostridiaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS1_k127_3604208_7	649747.HMPREF0083_01561	1.162e-57	204.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HV0C@91061|Bacilli,271MY@186822|Paenibacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS1_k127_3604832_8	521011.Mpal_0552	1.234e-46	178.0	COG0122@1|root,arCOG00464@2157|Archaea,2XU5Y@28890|Euryarchaeota,2N9M2@224756|Methanomicrobia	224756|Methanomicrobia	L	8-oxoguanine DNA glycosylase domain protein	-	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
LZS1_k127_3604832_6	306281.AJLK01000030_gene1321	2.729e-63	224.0	COG1839@1|root,COG1839@2|Bacteria,1G575@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
LZS1_k127_3604832_12	439481.Aboo_0010	8.767e-07	62.0	COG1361@1|root,COG1572@1|root,arCOG01917@1|root,arCOG01917@2157|Archaea,arCOG02079@2157|Archaea,arCOG02532@2157|Archaea,2Y1TH@28890|Euryarchaeota,3F2UJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DZR,zinc_ribbon_2
LZS1_k127_3604832_7	1347369.CCAD010000094_gene2268	2.384e-54	216.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,1ZBKI@1386|Bacillus	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS1_k127_3604832_3	1236689.MMALV_16700	6.527e-151	488.0	COG0422@1|root,arCOG02741@2157|Archaea,2XTMD@28890|Euryarchaeota,3F2I2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
LZS1_k127_3604832_1	1121430.JMLG01000002_gene1327	8.299e-267	837.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,260WQ@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
LZS1_k127_3604832_0	1256908.HMPREF0373_02804	1.121e-270	857.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,25UZ0@186806|Eubacteriaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS1_k127_3604832_10	439481.Aboo_1545	1.592e-22	107.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4JI@28890|Euryarchaeota,3F328@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	DnaB-like helicase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_3604832_9	439481.Aboo_0010	2.962e-39	171.0	COG1361@1|root,COG1572@1|root,arCOG01917@1|root,arCOG01917@2157|Archaea,arCOG02079@2157|Archaea,arCOG02532@2157|Archaea,2Y1TH@28890|Euryarchaeota,3F2UJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DZR,zinc_ribbon_2
LZS1_k127_3604832_2	439481.Aboo_0009	1.004e-223	706.0	COG4962@1|root,arCOG01817@2157|Archaea,2XT4E@28890|Euryarchaeota,3F2TI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II/IV secretion system protein	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS1_k127_3604832_5	439481.Aboo_0008	7.579e-64	233.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota,3F37F@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
LZS1_k127_3604832_4	439481.Aboo_0007	4.484e-84	291.0	COG2064@1|root,arCOG01808@2157|Archaea,2XT4Q@28890|Euryarchaeota,3F36C@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II secretion system	-	-	-	ko:K07333	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSF
LZS1_k127_3604832_11	439481.Aboo_0006	3.287e-22	98.0	COG4962@1|root,arCOG01817@2157|Archaea,2XT4E@28890|Euryarchaeota,3F381@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II/IV secretion system protein	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS1_k127_3676188_6	1183377.Py04_0762	3.64e-32	129.0	COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci	183968|Thermococci	J	Endoribonuclease L-PSP	-	GO:0003674,GO:0003824,GO:0016787,GO:0019239	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS1_k127_3676188_0	1121945.ATXS01000019_gene933	5.314e-114	387.0	COG1574@1|root,arCOG00691@2157|Archaea,2XUUZ@28890|Euryarchaeota,23SFX@183963|Halobacteria	183963|Halobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS1_k127_3676188_7	1521187.JPIM01000023_gene799	3.293e-27	120.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
LZS1_k127_3676188_10	331869.BAL199_25634	3.506e-09	68.0	COG0477@1|root,COG2814@2|Bacteria,1QW9T@1224|Proteobacteria,2TY4I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_3676188_8	595536.ADVE02000001_gene1375	1.213e-15	91.0	COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria,2U3GA@28211|Alphaproteobacteria,36ZMW@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
LZS1_k127_3676188_4	326298.Suden_1369	1.304e-38	157.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,42MUA@68525|delta/epsilon subdivisions,2YRF0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS1_k127_3676188_2	490899.DKAM_0838	2.91e-53	198.0	COG2820@1|root,arCOG01324@2157|Archaea,2XPX2@28889|Crenarchaeota	28889|Crenarchaeota	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS1_k127_3676188_9	673860.AciM339_1507	4.01e-10	72.0	COG0423@1|root,COG0525@1|root,arCOG00405@2157|Archaea,arCOG00808@2157|Archaea,2XSXQ@28890|Euryarchaeota,3F2GU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Anticodon-binding domain of tRNA	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A1976	Anticodon_1,tRNA-synt_1
LZS1_k127_3676188_5	589924.Ferp_1380	3.97e-37	153.0	COG1407@1|root,arCOG01150@2157|Archaea,2XWNG@28890|Euryarchaeota,24684@183980|Archaeoglobi	183980|Archaeoglobi	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos_2
LZS1_k127_3676188_3	797114.C475_08751	6.345e-52	193.0	COG3359@1|root,arCOG03130@2157|Archaea,2XUES@28890|Euryarchaeota,23SXR@183963|Halobacteria	183963|Halobacteria	L	exonuclease	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
LZS1_k127_3676188_1	673860.AciM339_1443	8.063e-59	215.0	COG0608@1|root,arCOG00427@2157|Archaea,2XT8Y@28890|Euryarchaeota,3F2FV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DHHA1 domain	recJ	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
LZS1_k127_3693599_0	931626.Awo_c07540	8.343e-19	94.0	COG5598@1|root,COG5598@2|Bacteria,1UY21@1239|Firmicutes,248BQ@186801|Clostridia	186801|Clostridia	H	PFAM Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
LZS1_k127_3762664_5	666685.R2APBS1_3798	1.233e-39	154.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,1RZGS@1236|Gammaproteobacteria,1XBRV@135614|Xanthomonadales	135614|Xanthomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS1_k127_3762664_3	399549.Msed_0440	4.519e-80	291.0	COG1506@1|root,arCOG01646@2157|Archaea,2XQMK@28889|Crenarchaeota	28889|Crenarchaeota	E	Peptidase S9 prolyl oligopeptidase active site domain protein	apeH-1	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
LZS1_k127_3762664_2	644968.DFW101_3315	8.173e-97	326.0	COG0492@1|root,COG0526@1|root,COG0492@2|Bacteria,COG0526@2|Bacteria,1R05R@1224|Proteobacteria,42QEV@68525|delta/epsilon subdivisions,2WMBG@28221|Deltaproteobacteria,2M9F6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
LZS1_k127_3762664_4	1229909.NSED_09745	2.199e-41	170.0	COG3263@1|root,arCOG01962@2157|Archaea,41SV3@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Sodium hydrogen exchanger	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger
LZS1_k127_3762664_0	349161.Dred_2987	7.98e-168	537.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,2600A@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
LZS1_k127_3762664_1	1054217.TALC_01538	1.895e-125	411.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,241ID@183967|Thermoplasmata	183967|Thermoplasmata	L	helicase superfamily c-terminal domain	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
LZS1_k127_378510_1	533247.CRD_02951	6.427e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1HIQE@1161|Nostocales	1117|Cyanobacteria	K	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS1_k127_378510_2	1514668.JOOA01000002_gene1009	0.0009617	53.0	COG5337@1|root,COG5337@2|Bacteria,1UZ0S@1239|Firmicutes,24UMA@186801|Clostridia,3WRYB@541000|Ruminococcaceae	186801|Clostridia	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CotH,Fn3_assoc,LTD
LZS1_k127_378510_0	673860.AciM339_0019	4.232e-35	156.0	COG0457@1|root,arCOG02493@1|root,arCOG02493@2157|Archaea,arCOG03038@2157|Archaea	2157|Archaea	KLT	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	HTH_24,PQQ_2,PQQ_3,TPR_12,TPR_16,TPR_2,TPR_8
LZS1_k127_3918478_3	1379698.RBG1_1C00001G1267	4.858e-41	169.0	COG0419@1|root,COG0419@2|Bacteria,2NPX7@2323|unclassified Bacteria	2|Bacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SMC_N,SbcCD_C
LZS1_k127_3918478_2	351160.RCIX1258	3.081e-71	250.0	COG1801@1|root,arCOG04291@2157|Archaea,2XY6C@28890|Euryarchaeota,2NA4H@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS1_k127_3918478_7	118161.KB235917_gene143	9.182e-21	101.0	COG1451@1|root,COG1451@2|Bacteria,1G5F8@1117|Cyanobacteria,3VIQX@52604|Pleurocapsales	1117|Cyanobacteria	S	SprT-like family	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
LZS1_k127_3918478_6	1347342.BN863_31370	7.395e-22	108.0	COG1357@1|root,COG2234@1|root,COG1357@2|Bacteria,COG2234@2|Bacteria,4NIQX@976|Bacteroidetes,1I0UI@117743|Flavobacteriia	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS1_k127_3918478_4	1198449.ACAM_1301	5.189e-34	136.0	COG1051@1|root,arCOG01075@2157|Archaea,2XR8E@28889|Crenarchaeota	28889|Crenarchaeota	L	PFAM NUDIX hydrolase	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
LZS1_k127_3918478_0	1333523.L593_06205	3.799e-116	402.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria	183963|Halobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2,Usp
LZS1_k127_3918478_1	555088.DealDRAFT_2079	6.184e-74	272.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
LZS1_k127_3918478_9	870187.Thini_1774	1.091e-10	76.0	COG2885@1|root,COG2885@2|Bacteria,1R508@1224|Proteobacteria,1RS7G@1236|Gammaproteobacteria,46256@72273|Thiotrichales	72273|Thiotrichales	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS1_k127_3918478_8	156578.ATW7_18195	6.249e-19	104.0	COG2133@1|root,COG2911@1|root,COG3209@1|root,COG3386@1|root,COG2133@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3386@2|Bacteria,1P8N9@1224|Proteobacteria,1SCTK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,DUF5122,He_PIG,OmpA_membrane
LZS1_k127_3918478_10	644281.MFS40622_0254	1.827e-07	66.0	arCOG02499@1|root,arCOG02499@2157|Archaea,2Y7Q6@28890|Euryarchaeota,23QW5@183939|Methanococci	183939|Methanococci	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
LZS1_k127_3918478_5	1521187.JPIM01000023_gene799	1.874e-30	127.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
LZS1_k127_3952904_2	304371.MCP_0449	2.661e-33	136.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,2NAP4@224756|Methanomicrobia	224756|Methanomicrobia	C	CoA binding domain	acdA	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
LZS1_k127_3952904_3	397945.Aave_2825	2.503e-19	98.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,4A9YD@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_3952904_1	1459636.NTE_01976	7.734e-57	214.0	COG0475@1|root,arCOG01953@2157|Archaea,41T00@651137|Thaumarchaeota	2157|Archaea	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
LZS1_k127_3952904_0	1236689.MMALV_09960	8.427e-103	344.0	COG0017@1|root,arCOG00406@2157|Archaea,2XTRE@28890|Euryarchaeota,3F2GB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12,6.1.1.23	ko:K09759,ko:K22503	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS1_k127_3971332_2	477974.Daud_1317	3.522e-57	213.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,261KK@186807|Peptococcaceae	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
LZS1_k127_3971332_1	767817.Desgi_2383	1.939e-78	274.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,260WJ@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
LZS1_k127_3971332_0	351160.RRC303	5.727e-105	359.0	COG1120@1|root,arCOG00199@2157|Archaea,2XTTV@28890|Euryarchaeota,2NA71@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
LZS1_k127_3971332_4	797209.ZOD2009_06799	2.339e-23	109.0	COG1497@1|root,arCOG04399@2157|Archaea,2XU16@28890|Euryarchaeota,23T3G@183963|Halobacteria	183963|Halobacteria	K	Transcriptional regulator	-	-	-	ko:K07730	-	-	-	-	ko00000,ko03000	-	-	-	HTH_24,MarR_2
LZS1_k127_3971332_3	459349.CLOAM1791	1.571e-28	125.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS1_k127_4010940_1	1304874.JAFY01000002_gene574	4.756e-81	289.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_4010940_2	1121007.AUML01000033_gene2796	2.328e-50	193.0	COG0498@1|root,COG0498@2|Bacteria,4NKWI@976|Bacteroidetes,1HZYM@117743|Flavobacteriia,2YHK1@290174|Aquimarina	976|Bacteroidetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	LeuA_dimer,PALP
LZS1_k127_4010940_0	579137.Metvu_1395	2.585e-110	365.0	COG0028@1|root,arCOG01998@2157|Archaea,2XT5F@28890|Euryarchaeota,23Q9X@183939|Methanococci	183939|Methanococci	E	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS1_k127_4109966_3	673860.AciM339_1054	4.277e-17	86.0	arCOG06948@1|root,arCOG06948@2157|Archaea,2XWV7@28890|Euryarchaeota,3F32R@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_4
LZS1_k127_4109966_2	706587.Desti_5096	3.043e-17	85.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
LZS1_k127_4109966_1	485913.Krac_6636	4.301e-18	97.0	COG0642@1|root,COG2205@2|Bacteria	485913.Krac_6636|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4116349_1	1134413.ANNK01000126_gene2546	7.968e-09	68.0	COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus	91061|Bacilli	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
LZS1_k127_4116349_0	1236689.MMALV_12000	4.72e-23	104.0	COG1549@1|root,arCOG00990@2157|Archaea,2XT9W@28890|Euryarchaeota,3F2KU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Patch-forming domain C2 of tRNA-guanine transglycosylase	arcS	GO:0002927,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.6.1.97	ko:K07557	-	-	-	-	ko00000,ko01000	-	-	-	PUA,TGT,TGT_C2
LZS1_k127_4118744_1	1236689.MMALV_12510	3.092e-08	56.0	COG0124@1|root,arCOG00404@2157|Archaea,2XSYX@28890|Euryarchaeota,3F2K8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
LZS1_k127_4118744_0	555079.Toce_1201	1.811e-38	145.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS1_k127_4124724_3	1123371.ATXH01000012_gene1459	4.144e-07	53.0	COG1402@1|root,COG1402@2|Bacteria,2GH3V@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS1_k127_4124724_1	391623.TERMP_01129	4.612e-61	219.0	COG2102@1|root,arCOG00035@2157|Archaea,2XTNJ@28890|Euryarchaeota,242TE@183968|Thermococci	183968|Thermococci	S	Diphthamide synthase	-	-	6.3.1.14	ko:K06927	-	-	R03613	RC00358	ko00000,ko01000,ko03012	-	-	-	Diphthami_syn_2
LZS1_k127_4124724_0	1304284.L21TH_0215	1.051e-174	558.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,36E9A@31979|Clostridiaceae	186801|Clostridia	E	lysine 2,3-aminomutase YodO family protein	ablA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
LZS1_k127_4124724_2	529709.PYCH_13260	1.497e-56	202.0	COG0127@1|root,arCOG04184@2157|Archaea,2XTS4@28890|Euryarchaeota,243RS@183968|Thermococci	183968|Thermococci	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
LZS1_k127_4125174_2	1536769.P40081_10040	2.621e-06	59.0	COG0477@1|root,COG2814@2|Bacteria,1UI43@1239|Firmicutes,4ISCR@91061|Bacilli,26RSR@186822|Paenibacillaceae	91061|Bacilli	EGP	Major facilitator superfamily	yqgE	-	-	ko:K08222	-	-	-	-	ko00000,ko02000	2.A.1.33	-	-	MFS_1
LZS1_k127_4125174_1	523845.AQXV01000046_gene841	1.843e-12	68.0	COG1986@1|root,arCOG01221@2157|Archaea,2XWMP@28890|Euryarchaeota,23QUT@183939|Methanococci	183939|Methanococci	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	-	GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
LZS1_k127_4125174_0	1236689.MMALV_01750	5.171e-18	85.0	COG0157@1|root,arCOG01482@2157|Archaea,2XTTY@28890|Euryarchaeota,3F2NB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Involved in the catabolism of quinolinic acid (QA)	nadC	GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A1867	QRPTase_C,QRPTase_N
LZS1_k127_4140537_0	1236689.MMALV_02090	9.438e-90	308.0	COG0644@1|root,arCOG00570@2157|Archaea,2XU3J@28890|Euryarchaeota,3F2EW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	1.3.1.101,1.3.7.11,1.5.5.1	ko:K00311,ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored,Lycopene_cycl,Trp_halogenase
LZS1_k127_4140537_4	1236689.MMALV_02100	3.594e-27	119.0	COG1439@1|root,arCOG00721@2157|Archaea,2XWH2@28890|Euryarchaeota,3F2SW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	PIN domain of ribonuclease	nob1	GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0030490,GO:0030684,GO:0030688,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1990904	-	ko:K07060	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN_6
LZS1_k127_4140537_3	521011.Mpal_1938	3.67e-63	224.0	COG0301@1|root,arCOG00038@2157|Archaea,2XYMB@28890|Euryarchaeota,2NBHY@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	ThiI
LZS1_k127_4140537_2	868131.MSWAN_1002	8.876e-69	242.0	COG0476@1|root,arCOG09483@1|root,arCOG01676@2157|Archaea,arCOG09483@2157|Archaea,2XTYV@28890|Euryarchaeota	28890|Euryarchaeota	H	UBA THIF-type NAD FAD binding protein	-	-	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	TBP,ThiF
LZS1_k127_4140537_1	439481.Aboo_0635	4.916e-80	278.0	COG0112@1|root,arCOG00070@2157|Archaea,2XX80@28890|Euryarchaeota,3F334@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Serine hydroxymethyltransferase	-	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
LZS1_k127_4149490_3	429009.Adeg_1087	2.377e-07	54.0	COG1433@1|root,COG1433@2|Bacteria,1VFDZ@1239|Firmicutes,24R8N@186801|Clostridia,42GPN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
LZS1_k127_4149490_2	760568.Desku_1894	7.466e-31	128.0	COG0822@1|root,COG0822@2|Bacteria,1VCI2@1239|Firmicutes,24MWW@186801|Clostridia,265KS@186807|Peptococcaceae	186801|Clostridia	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
LZS1_k127_4149490_1	269797.Mbar_A1833	5.831e-37	143.0	COG1433@1|root,arCOG02734@2157|Archaea,2XYU9@28890|Euryarchaeota,2NA47@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
LZS1_k127_4149490_0	693661.Arcve_1605	1.113e-65	230.0	COG1149@1|root,arCOG04073@2157|Archaea,2XWI1@28890|Euryarchaeota	28890|Euryarchaeota	D	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4,Fer4_6
LZS1_k127_4162936_1	1236689.MMALV_15520	1.402e-16	81.0	arCOG14617@1|root,arCOG14617@2157|Archaea,2Y5TW@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4162936_0	1236689.MMALV_12580	4.72e-27	111.0	COG1163@1|root,arCOG00358@2157|Archaea,2XTYK@28890|Euryarchaeota,3F2I6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	C-terminal region of MMR_HSR1 domain	drg	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
LZS1_k127_4167776_0	673860.AciM339_1477	2.051e-57	205.0	COG2047@1|root,arCOG00348@2157|Archaea,2XSX4@28890|Euryarchaeota,3F2K5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PAC2 family	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
LZS1_k127_4167776_2	1333523.L593_10940	6.764e-06	51.0	COG3609@1|root,arCOG01009@2157|Archaea,2XZTH@28890|Euryarchaeota,23XHR@183963|Halobacteria	183963|Halobacteria	K	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
LZS1_k127_4167776_1	1094980.Mpsy_2611	9.399e-18	90.0	COG0745@1|root,arCOG02348@1|root,arCOG03799@1|root,arCOG02348@2157|Archaea,arCOG02592@2157|Archaea,arCOG03799@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF835)	-	-	2.7.7.65,6.3.4.2	ko:K01937,ko:K02488	ko00240,ko01100,ko02020,ko04112,map00240,map01100,map02020,map04112	M00052,M00511	R00571,R00573,R08057	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	DUF835,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_4184720_2	521011.Mpal_1759	3.861e-53	191.0	COG1122@1|root,arCOG00202@2157|Archaea,2XT28@28890|Euryarchaeota,2NAK6@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
LZS1_k127_4184720_1	351160.LRC577	9.107e-54	199.0	COG0619@1|root,arCOG02250@2157|Archaea,2Y8G4@28890|Euryarchaeota,2NAGW@224756|Methanomicrobia	224756|Methanomicrobia	P	Cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
LZS1_k127_4184720_0	521011.Mpal_1638	2.386e-56	204.0	COG0310@1|root,arCOG02248@2157|Archaea,2XTXA@28890|Euryarchaeota,2NAQR@224756|Methanomicrobia	224756|Methanomicrobia	P	Cobalt uptake substrate-specific transmembrane region	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
LZS1_k127_4188080_4	648757.Rvan_3140	5.499e-19	91.0	COG1961@1|root,COG1961@2|Bacteria,1R3XB@1224|Proteobacteria,2U5C4@28211|Alphaproteobacteria,3N74H@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
LZS1_k127_4188080_3	1054217.TALC_00353	4.81e-23	113.0	COG0582@1|root,arCOG01241@2157|Archaea,2Y5FD@28890|Euryarchaeota	2157|Archaea	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
LZS1_k127_4188080_5	1499967.BAYZ01000050_gene2853	6.71e-19	94.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdxB	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
LZS1_k127_4188080_2	886293.Sinac_3443	3.712e-65	226.0	COG0225@1|root,COG0225@2|Bacteria,2IZ67@203682|Planctomycetes	203682|Planctomycetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
LZS1_k127_4188080_1	644966.Tmar_0462	9.11e-112	385.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,3WDH0@538999|Clostridiales incertae sedis	186801|Clostridia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
LZS1_k127_4188080_0	304371.MCP_0970	2.809e-141	464.0	COG1249@1|root,arCOG01068@2157|Archaea,2XTJE@28890|Euryarchaeota,2N9NV@224756|Methanomicrobia	224756|Methanomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS1_k127_4188080_6	309800.C498_08575	1.637e-14	88.0	COG0642@1|root,arCOG02387@1|root,arCOG06712@1|root,arCOG02387@2157|Archaea,arCOG06408@2157|Archaea,arCOG06712@2157|Archaea,2Y149@28890|Euryarchaeota	28890|Euryarchaeota	T	COG0784 FOG CheY-like receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_4210374_0	1054217.TALC_00075	5.289e-36	143.0	COG0438@1|root,arCOG01411@2157|Archaea,2Y8C9@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS1_k127_4210374_1	269797.Mbar_A2010	3.6e-14	83.0	COG0671@1|root,arCOG03951@2157|Archaea,2Y0A1@28890|Euryarchaeota,2NAVS@224756|Methanomicrobia	224756|Methanomicrobia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
LZS1_k127_4210374_2	439481.Aboo_1533	3.538e-10	68.0	COG1047@1|root,arCOG00981@2157|Archaea,2Y6YB@28890|Euryarchaeota,3F2VV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
LZS1_k127_4218105_1	673860.AciM339_0267	4.569e-124	410.0	COG0402@1|root,arCOG00695@2157|Archaea,2XTJS@28890|Euryarchaeota,3F2GI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Amidohydrolase family	dadD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
LZS1_k127_4218105_0	1054217.TALC_00940	3.231e-140	454.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTA2@28890|Euryarchaeota,241RS@183967|Thermoplasmata	183967|Thermoplasmata	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS1_k127_4218105_3	1054217.TALC_00939	5.808e-27	115.0	COG1585@1|root,arCOG01912@2157|Archaea,2Y07X@28890|Euryarchaeota	28890|Euryarchaeota	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
LZS1_k127_4218105_2	673860.AciM339_1091	2.261e-48	178.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,3F3BR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS1_k127_4218105_4	673860.AciM339_0074	1.363e-15	86.0	COG1236@1|root,arCOG00541@2157|Archaea,2XTIU@28890|Euryarchaeota,3F2F9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Beta-Casp domain	epf1	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
LZS1_k127_4234034_3	673860.AciM339_1562	8.157e-68	237.0	COG0466@1|root,arCOG02162@2157|Archaea,2XVMC@28890|Euryarchaeota,3F2HJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	AAA domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Mg_chelatase,Sigma54_activat
LZS1_k127_4234034_0	673860.AciM339_1561	2.33e-128	425.0	COG0358@1|root,arCOG04281@2157|Archaea,2XTHB@28890|Euryarchaeota,3F2FZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Toprim domain	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4
LZS1_k127_4234034_7	399550.Smar_1601	1.931e-09	60.0	COG2104@1|root,arCOG00535@2157|Archaea,2XRHV@28889|Crenarchaeota	28889|Crenarchaeota	H	thiamineS protein	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS1_k127_4234034_4	1382356.JQMP01000003_gene1324	8.61e-41	166.0	COG0477@1|root,COG2814@2|Bacteria,2G9Z5@200795|Chloroflexi,27XES@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_4234034_1	439481.Aboo_1101	7.222e-127	425.0	COG3635@1|root,arCOG01696@2157|Archaea,2XTE8@28890|Euryarchaeota,3F2ZT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
LZS1_k127_4234034_6	589924.Ferp_0047	2.937e-18	87.0	COG2151@1|root,arCOG01845@2157|Archaea,2Y7ED@28890|Euryarchaeota,2475T@183980|Archaeoglobi	183980|Archaeoglobi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
LZS1_k127_4234034_5	589924.Ferp_0134	1.061e-21	104.0	COG3413@1|root,arCOG02271@2157|Archaea,2XU8X@28890|Euryarchaeota	28890|Euryarchaeota	K	Bacterio-opsin activator HTH domain-containing protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,HTH_10
LZS1_k127_4234034_2	304371.MCP_1816	5.355e-85	291.0	COG1602@1|root,arCOG04269@2157|Archaea,2XTEQ@28890|Euryarchaeota,2NADJ@224756|Methanomicrobia	224756|Methanomicrobia	S	Pfam:DUF650	-	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
LZS1_k127_4240294_1	304371.MCP_2263	3.252e-22	98.0	COG1531@1|root,arCOG01302@2157|Archaea	2157|Archaea	S	Belongs to the UPF0248 family	-	-	-	ko:K09715	-	-	-	-	ko00000	-	-	-	DUF504
LZS1_k127_4240294_0	1157490.EL26_11975	5.403e-81	293.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	PKD,PPC,Peptidase_M10,Peptidase_M28,SLH
LZS1_k127_4258477_0	555088.DealDRAFT_0595	6.266e-210	664.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,42KZ0@68298|Syntrophomonadaceae	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS1_k127_4258477_10	760568.Desku_3249	1.474e-07	61.0	COG2009@1|root,COG2009@2|Bacteria,1VKGI@1239|Firmicutes,24VB1@186801|Clostridia	186801|Clostridia	C	TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
LZS1_k127_4258477_8	760568.Desku_3249	6.264e-18	91.0	COG2009@1|root,COG2009@2|Bacteria,1VKGI@1239|Firmicutes,24VB1@186801|Clostridia	186801|Clostridia	C	TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
LZS1_k127_4258477_6	273068.TTE2154	4.293e-23	99.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,42H59@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
LZS1_k127_4258477_2	580340.Tlie_1159	4.44e-83	287.0	COG0460@1|root,COG0460@2|Bacteria,3TA0A@508458|Synergistetes	508458|Synergistetes	E	PFAM Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
LZS1_k127_4258477_11	1151117.AJLF01000001_gene1119	1.075e-06	57.0	COG1633@1|root,arCOG01102@2157|Archaea,2Y3HF@28890|Euryarchaeota,2446K@183968|Thermococci	183968|Thermococci	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS1_k127_4258477_3	484770.UFO1_1017	4.624e-71	248.0	COG1028@1|root,COG1028@2|Bacteria,1TPHT@1239|Firmicutes,4H8V7@909932|Negativicutes	909932|Negativicutes	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS1_k127_4258477_5	1041930.Mtc_2045	1.662e-33	146.0	COG2202@1|root,arCOG03931@1|root,arCOG03931@2157|Archaea,arCOG06515@2157|Archaea	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,GAF_2,HATPase_c,HTH_10,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phage_integrase,Response_reg
LZS1_k127_4258477_7	1379698.RBG1_1C00001G1780	3.466e-21	96.0	COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria	2|Bacteria	O	peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
LZS1_k127_4258477_1	1121459.AQXE01000001_gene2889	1.115e-87	299.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,42NRH@68525|delta/epsilon subdivisions,2WNIB@28221|Deltaproteobacteria,2MAD0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
LZS1_k127_4258477_9	439481.Aboo_0741	5.443e-10	70.0	COG1672@1|root,COG3398@1|root,arCOG02611@2157|Archaea,arCOG03166@2157|Archaea	2157|Archaea	K	ATPase, AAA superfamily	deoR2	-	3.6.4.12,4.2.3.1,6.3.4.15	ko:K01733,ko:K02039,ko:K03436,ko:K03524,ko:K03655	ko00260,ko00750,ko00780,ko01100,ko01110,ko01120,ko01230,ko03440,map00260,map00750,map00780,map01100,map01110,map01120,map01230,map03440	M00018	R01074,R01466,R05086,R05145	RC00017,RC00043,RC00070,RC00096,RC00526,RC02896	ko00000,ko00001,ko00002,ko01000,ko03000,ko03400	-	-	-	BPL_C,BPL_LplA_LipB,DeoRC,HTH_11,HTH_24,HTH_DeoR,MarR_2,PhoU
LZS1_k127_4258477_4	273075.Ta1469	1.258e-35	152.0	arCOG00138@1|root,arCOG00138@2157|Archaea	2157|Archaea	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_4283164_4	410358.Mlab_1654	1.02e-100	334.0	COG1830@1|root,arCOG04044@2157|Archaea,2XTBQ@28890|Euryarchaeota,2N9E2@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids	aroF	-	2.2.1.10,4.1.2.13	ko:K16306	ko00010,ko00030,ko00051,ko00400,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00400,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001	R01068,R01070,R02568,R08568	RC00438,RC00439,RC00721,RC02301	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0920	DeoC
LZS1_k127_4283164_5	410358.Mlab_1653	2.714e-90	308.0	COG1465@1|root,arCOG04353@2157|Archaea,2XSXD@28890|Euryarchaeota,2N9AV@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis	aroB'	-	1.4.1.24	ko:K11646	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R08569	RC02302	ko00000,ko00001,ko01000	-	-	-	DHQS
LZS1_k127_4283164_6	410358.Mlab_1652	5.825e-61	229.0	COG0169@1|root,arCOG01033@2157|Archaea,arCOG02097@2157|Archaea,2XV7K@28890|Euryarchaeota,2N9IF@224756|Methanomicrobia	224756|Methanomicrobia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25,2.7.1.71,4.2.1.10	ko:K00014,ko:K00891,ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R02413,R03084	RC00002,RC00078,RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0923	SKI,Shikimate_DH,Shikimate_dh_N
LZS1_k127_4283164_9	410358.Mlab_1651	1.801e-38	160.0	COG1685@1|root,arCOG01025@2157|Archaea,2XUI2@28890|Euryarchaeota,2N96J@224756|Methanomicrobia	224756|Methanomicrobia	E	shikimate kinase activity	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A3127	GHMP_kinases_N
LZS1_k127_4283164_3	1236689.MMALV_05140	7.908e-103	351.0	COG0128@1|root,arCOG04134@2157|Archaea,2XTC3@28890|Euryarchaeota	28890|Euryarchaeota	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
LZS1_k127_4283164_1	1286171.EAL2_c00930	1.414e-110	368.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,25URP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
LZS1_k127_4283164_8	502025.Hoch_6599	4.752e-45	183.0	COG0287@1|root,COG1605@1|root,COG0287@2|Bacteria,COG1605@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria,2YW0I@29|Myxococcales	28221|Deltaproteobacteria	E	Prephenate dehydrogenase chorismate mutase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
LZS1_k127_4283164_2	1236689.MMALV_04960	3.637e-104	365.0	COG0136@1|root,arCOG00494@2157|Archaea,2XTKH@28890|Euryarchaeota	28890|Euryarchaeota	E	aspartate-semialdehyde dehydrogenase	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS1_k127_4283164_0	1304880.JAGB01000003_gene1272	9.731e-147	490.0	COG1900@1|root,COG1900@2|Bacteria,1TRBF@1239|Firmicutes,248FE@186801|Clostridia	186801|Clostridia	C	Homocysteine biosynthesis enzyme, sulfur-incorporation	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,HcyBio
LZS1_k127_4283164_10	1121438.JNJA01000004_gene757	2.097e-33	133.0	COG1145@1|root,COG1145@2|Bacteria,1QWP6@1224|Proteobacteria,43BU8@68525|delta/epsilon subdivisions,2X759@28221|Deltaproteobacteria,2MHBZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM NIL domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_7,NIL
LZS1_k127_4283164_7	1041930.Mtc_0353	2.853e-50	188.0	COG2122@1|root,arCOG04376@2157|Archaea,2XV48@28890|Euryarchaeota,2N9HW@224756|Methanomicrobia	224756|Methanomicrobia	S	Belongs to the UPF0280 family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
LZS1_k127_4283164_11	866536.Belba_1151	4.169e-08	56.0	COG0527@1|root,COG0527@2|Bacteria,4NFWR@976|Bacteroidetes,47KM0@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
LZS1_k127_4289722_1	1457250.BBMO01000003_gene3021	2.023e-11	65.0	COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,23TBN@183963|Halobacteria	183963|Halobacteria	G	COG1109 Phosphomannomutase	pmm4	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS1_k127_4289722_0	1094980.Mpsy_2687	1.131e-81	281.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,2N9G1@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transferase
LZS1_k127_4300422_2	383372.Rcas_1205	2.567e-61	217.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi,374VE@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
LZS1_k127_4300422_0	673860.AciM339_0759	9.996e-77	272.0	COG1468@1|root,arCOG00786@2157|Archaea,2Y71A@28890|Euryarchaeota,3F34X@33867|unclassified Euryarchaeota	28890|Euryarchaeota	V	TIGRFAM CRISPR-associated protein Cas4	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PDDEXK_1
LZS1_k127_4300422_1	1236689.MMALV_14300	1.06e-65	236.0	arCOG04990@1|root,arCOG04990@2157|Archaea,2XYVI@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function TPD sequence-motif	-	-	-	-	-	-	-	-	-	-	-	-	TPD
LZS1_k127_4300422_3	484770.UFO1_1436	1.532e-33	137.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4H3R3@909932|Negativicutes	909932|Negativicutes	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
LZS1_k127_4308174_0	1122994.AUFR01000007_gene1011	0.000955	49.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4DWWD@85009|Propionibacteriales	201174|Actinobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS1_k127_433286_1	319225.Plut_1668	4.566e-66	248.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
LZS1_k127_433286_4	1236689.MMALV_09700	1.727e-06	58.0	COG0582@1|root,arCOG01241@2157|Archaea	2157|Archaea	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
LZS1_k127_433286_3	706587.Desti_2838	7.071e-35	144.0	COG1149@1|root,COG1149@2|Bacteria,1R09H@1224|Proteobacteria,43CSK@68525|delta/epsilon subdivisions,2X808@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
LZS1_k127_433286_2	1236689.MMALV_03280	1.015e-48	175.0	COG0051@1|root,arCOG01758@2157|Archaea,2XXV8@28890|Euryarchaeota,3F2QH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Involved in the binding of tRNA to the ribosomes	rps10	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
LZS1_k127_433286_0	368407.Memar_0730	3.221e-199	626.0	COG5256@1|root,arCOG01561@2157|Archaea,2XTNM@28890|Euryarchaeota,2N9FZ@224756|Methanomicrobia	224756|Methanomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03231	ko03013,ko05134,map03013,map05134	-	-	-	ko00000,ko00001,ko03012,ko03016,ko03019,ko04131,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS1_k127_435139_5	1054217.TALC_00119	1.383e-62	217.0	COG3276@1|root,arCOG01563@2157|Archaea,2XUKU@28890|Euryarchaeota,241M1@183967|Thermoplasmata	183967|Thermoplasmata	J	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA	eif2g	-	-	ko:K03242	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,eIF2_C
LZS1_k127_435139_9	673860.AciM339_0274	4.106e-43	161.0	COG2125@1|root,arCOG01946@2157|Archaea,2XXZJ@28890|Euryarchaeota,3F2RJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS6 family	rps6e	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904	-	ko:K02991	ko01521,ko03010,ko04066,ko04150,ko04151,ko04371,ko04714,ko04910,ko05205,map01521,map03010,map04066,map04150,map04151,map04371,map04714,map04910,map05205	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S6e
LZS1_k127_435139_1	439481.Aboo_0942	2.261e-209	666.0	COG0532@1|root,arCOG01560@2157|Archaea,2XU09@28890|Euryarchaeota,3F2FJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2	infB	-	-	ko:K03243	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D4,IF-2,Intein_splicing,LAGLIDADG_3
LZS1_k127_435139_6	572546.Arcpr_0498	3.512e-56	206.0	COG0105@1|root,arCOG04313@2157|Archaea,2XWSK@28890|Euryarchaeota,2465T@183980|Archaeoglobi	183980|Archaeoglobi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
LZS1_k127_435139_11	439481.Aboo_1238	6.385e-21	96.0	COG2075@1|root,arCOG01950@2157|Archaea,2Y00Q@28890|Euryarchaeota,3F2UM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	binds to the 23S rRNA	rpl24e	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02896	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L24e
LZS1_k127_435139_10	1236689.MMALV_01050	1.546e-30	121.0	COG2053@1|root,arCOG04314@2157|Archaea,2XYMV@28890|Euryarchaeota,3F2S8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS28 family	rps28e	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904	-	ko:K02979	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S28e
LZS1_k127_435139_7	1054217.TALC_00112	3.024e-47	173.0	COG1358@1|root,arCOG01751@2157|Archaea,2XX4C@28890|Euryarchaeota,241TC@183967|Thermoplasmata	183967|Thermoplasmata	J	Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs	rpl7ae	-	-	ko:K02936	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03009,ko03011	-	-	-	Ribosomal_L7Ae
LZS1_k127_435139_2	589924.Ferp_1748	3.143e-167	547.0	COG0633@1|root,COG3894@1|root,arCOG02035@2157|Archaea,arCOG02842@2157|Archaea,2XVBE@28890|Euryarchaeota,246NQ@183980|Archaeoglobi	183980|Archaeoglobi	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
LZS1_k127_435139_3	1444309.JAQG01000005_gene4327	2.398e-80	283.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,4HA8B@91061|Bacilli,26USF@186822|Paenibacillaceae	91061|Bacilli	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
LZS1_k127_435139_4	1444309.JAQG01000005_gene4327	1.105e-76	271.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,4HA8B@91061|Bacilli,26USF@186822|Paenibacillaceae	91061|Bacilli	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
LZS1_k127_435139_12	1227495.C487_19528	5.944e-16	90.0	COG0477@1|root,arCOG00132@2157|Archaea,2XVCP@28890|Euryarchaeota,23UPN@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_435139_0	795359.TOPB45_0109	0.0	1035.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GHH0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS1_k127_435139_8	1123024.AUII01000034_gene2674	4.945e-46	184.0	COG0438@1|root,COG0438@2|Bacteria,2GKX4@201174|Actinobacteria,4E2H9@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS1_k127_435139_13	84531.JMTZ01000108_gene4272	3.592e-07	53.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1T171@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS1_k127_4362066_17	877455.Metbo_2406	4.119e-07	54.0	COG1014@1|root,arCOG01602@2157|Archaea,2XUK0@28890|Euryarchaeota,23PH1@183925|Methanobacteria	183925|Methanobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
LZS1_k127_4362066_10	673860.AciM339_0745	3.327e-48	180.0	COG1042@1|root,arCOG01338@2157|Archaea,2Y39C@28890|Euryarchaeota,3F35C@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	ATP-grasp domain	-	-	6.2.1.13	ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5
LZS1_k127_4362066_12	981369.JQMJ01000004_gene5162	2.2e-37	147.0	COG0688@1|root,COG0688@2|Bacteria,2GMMF@201174|Actinobacteria,2NH06@228398|Streptacidiphilus	201174|Actinobacteria	I	Phosphatidylserine decarboxylase	psd	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
LZS1_k127_4362066_13	572546.Arcpr_0869	4.752e-19	96.0	COG1183@1|root,arCOG00671@2157|Archaea,2XW1C@28890|Euryarchaeota,2477M@183980|Archaeoglobi	183980|Archaeoglobi	I	PFAM CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
LZS1_k127_4362066_11	439481.Aboo_0295	2.167e-39	150.0	COG2098@1|root,arCOG04705@2157|Archaea,2XY43@28890|Euryarchaeota,3F2SX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD)	mptD	-	4.1.2.25	ko:K09739	ko00790,map00790	-	R03504	RC00721,RC00943	ko00000,ko00001,ko01000	-	-	-	DHNA
LZS1_k127_4362066_8	673860.AciM339_0768	1.073e-70	244.0	COG1618@1|root,arCOG01034@2157|Archaea,2XX6U@28890|Euryarchaeota,3F2MF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
LZS1_k127_4362066_7	1236689.MMALV_10010	3.166e-71	261.0	COG1867@1|root,arCOG01219@2157|Archaea,2XTUF@28890|Euryarchaeota,3F2P9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family	trm1	GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.215,2.1.1.216	ko:K00555	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TRM
LZS1_k127_4362066_2	264732.Moth_2309	1.863e-143	467.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,42FKX@68295|Thermoanaerobacterales	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
LZS1_k127_4362066_0	1236689.MMALV_11600	1.16e-216	700.0	arCOG01305@1|root,arCOG01305@2157|Archaea,2Y7Q1@28890|Euryarchaeota	28890|Euryarchaeota	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
LZS1_k127_4362066_14	673860.AciM339_0022	3.66e-15	87.0	COG1522@1|root,arCOG01580@2157|Archaea,arCOG01585@2157|Archaea,2Y6YT@28890|Euryarchaeota,3F2Y0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4362066_15	269797.Mbar_A0674	5.674e-15	78.0	COG1552@1|root,arCOG04049@2157|Archaea,2Y177@28890|Euryarchaeota,2NB9F@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the eukaryotic ribosomal protein eL40 family	rpl40e	-	-	ko:K02927	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L40e
LZS1_k127_4362066_3	673860.AciM339_0861	5.954e-123	402.0	COG0470@1|root,arCOG00469@2157|Archaea,2XTC8@28890|Euryarchaeota,3F2I9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA	rfcS	GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576	-	ko:K04801	ko03030,map03030	-	-	-	ko00000,ko00001,ko03032	-	-	-	AAA,DNA_pol3_delta2,HTH_3,Intein_splicing,LAGLIDADG_3,Rad17,Rep_fac_C,RuvB_N
LZS1_k127_4362066_5	1236689.MMALV_10390	3.553e-96	323.0	COG0037@1|root,arCOG00042@2157|Archaea,2XTEZ@28890|Euryarchaeota,3F2HB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	PP-loop family	tuc1	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
LZS1_k127_4362066_16	439481.Aboo_1479	3.521e-10	70.0	arCOG13565@1|root,arCOG13565@2157|Archaea,2Y66R@28890|Euryarchaeota,3F331@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4362066_1	1236689.MMALV_10170	3.414e-158	510.0	COG0112@1|root,arCOG00070@2157|Archaea,2XU0H@28890|Euryarchaeota,3F2G1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
LZS1_k127_4362066_9	1121468.AUBR01000012_gene2574	1.238e-57	214.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,42EVQ@68295|Thermoanaerobacterales	186801|Clostridia	G	TIGRFAM bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
LZS1_k127_4362066_6	479434.Sthe_1775	1.215e-88	299.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_4362066_4	479434.Sthe_1776	1.629e-111	395.0	COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia	189775|Thermomicrobia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
LZS1_k127_4365230_3	1236689.MMALV_14060	1.157e-66	231.0	COG0098@1|root,arCOG04087@2157|Archaea,2XUQU@28890|Euryarchaeota,3F2HF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	With S4 and S12 plays an important role in translational accuracy	rps5	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
LZS1_k127_4365230_5	1236689.MMALV_14050	1.632e-43	163.0	COG1841@1|root,arCOG04086@2157|Archaea,2XWGP@28890|Euryarchaeota,3F2NM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Ribosomal protein L30p/L7e	rpl30	GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
LZS1_k127_4365230_7	1054217.TALC_01312	1.644e-40	154.0	COG0200@1|root,arCOG00779@2157|Archaea,2Y6A4@28890|Euryarchaeota,241UA@183967|Thermoplasmata	183967|Thermoplasmata	J	Binds to the 23S rRNA	rpl15	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
LZS1_k127_4365230_0	1236689.MMALV_14030	1.047e-214	678.0	COG5253@1|root,arCOG04169@2157|Archaea,2XT9A@28890|Euryarchaeota,3F2F6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	Plug_translocon,SecY
LZS1_k127_4365230_8	1054217.TALC_01310	6.742e-35	142.0	COG1422@1|root,arCOG02673@2157|Archaea,2XZDK@28890|Euryarchaeota,241UY@183967|Thermoplasmata	183967|Thermoplasmata	U	Integral membrane protein DUF106	-	-	-	-	-	-	-	-	-	-	-	-	DUF106
LZS1_k127_4365230_6	673860.AciM339_1124	4.131e-43	165.0	COG1102@1|root,arCOG01037@2157|Archaea,2XWPB@28890|Euryarchaeota,3F3AN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
LZS1_k127_4365230_1	573063.Metin_0669	3.018e-86	295.0	COG0130@1|root,arCOG00987@2157|Archaea,2XTUE@28890|Euryarchaeota,23QBK@183939|Methanococci	183939|Methanococci	J	Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs	truB	GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481	-	ko:K11131	ko03008,map03008	M00425	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03032	-	-	-	DKCLD,PUA,TruB_C_2,TruB_N
LZS1_k127_4365230_2	351160.RCIX2327	1.44e-77	271.0	COG1236@1|root,arCOG00545@2157|Archaea,2XT2R@28890|Euryarchaeota	28890|Euryarchaeota	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	-
LZS1_k127_4365230_4	673860.AciM339_0382	6.685e-51	197.0	COG1196@1|root,arCOG01917@1|root,arCOG02452@1|root,arCOG00371@2157|Archaea,arCOG01917@2157|Archaea,arCOG02452@2157|Archaea,2Y71H@28890|Euryarchaeota,3F35U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_4389023_16	673860.AciM339_0015	2.173e-05	48.0	arCOG02780@1|root,arCOG02780@2157|Archaea,2Y714@28890|Euryarchaeota,3F34G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4389023_7	415426.Hbut_1150	9.427e-32	129.0	COG1656@1|root,arCOG04290@2157|Archaea,2XQD5@28889|Crenarchaeota	28889|Crenarchaeota	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
LZS1_k127_4389023_5	439481.Aboo_0416	1.31e-58	212.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,3F2MK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	RibD C-terminal domain	ribG	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
LZS1_k127_4389023_4	439481.Aboo_0790	4.473e-67	237.0	COG1938@1|root,arCOG00347@2157|Archaea,2XT93@28890|Euryarchaeota,3F2T7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PAC2 family	-	-	-	ko:K06869	-	-	-	-	ko00000	-	-	-	PAC2
LZS1_k127_4389023_2	410359.Pcal_2009	1.079e-87	302.0	COG0430@1|root,arCOG04125@2157|Archaea,2XPT6@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
LZS1_k127_4389023_12	696281.Desru_1395	4.176e-19	100.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,24AKU@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator	-	-	-	ko:K08151,ko:K08153	-	M00668,M00717	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
LZS1_k127_4389023_3	1121428.DESHY_160033___1	1.375e-72	257.0	COG0530@1|root,COG0530@2|Bacteria,1UQT7@1239|Firmicutes,258JC@186801|Clostridia,260UA@186807|Peptococcaceae	186801|Clostridia	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS1_k127_4389023_6	262543.Exig_1459	3.912e-41	172.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,4HC99@91061|Bacilli,3WFT2@539002|Bacillales incertae sedis	91061|Bacilli	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
LZS1_k127_4389023_15	572478.Vdis_1036	8.882e-08	61.0	COG3371@1|root,arCOG02008@2157|Archaea,2XRYZ@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
LZS1_k127_4389023_1	688269.Theth_0565	1.201e-160	515.0	COG4992@1|root,COG4992@2|Bacteria,2GCYS@200918|Thermotogae	200918|Thermotogae	E	PFAM Aminotransferase class-III	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_4389023_14	1150474.JQJI01000017_gene593	8.687e-15	81.0	COG1661@1|root,COG1661@2|Bacteria,2GDE0@200918|Thermotogae	200918|Thermotogae	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
LZS1_k127_4389023_11	643648.Slip_1257	3.875e-20	106.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	ko:K02014,ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000,ko02042	1.B.14	-	-	Alginate_lyase2,CBM_6,CarbopepD_reg_2,F5_F8_type_C,Plug,Thiol_cytolys_C,Thiol_cytolysin,TonB_dep_Rec
LZS1_k127_4389023_10	1128421.JAGA01000001_gene2345	5.564e-21	109.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CARDB,CBM_3,DUF4091,HYR,Kelch_1,MAM,PA14,PKD,Peptidase_M43,Reprolysin_3
LZS1_k127_4389023_8	1236689.MMALV_00410	2.271e-25	108.0	COG1698@1|root,arCOG04308@2157|Archaea,2XZVX@28890|Euryarchaeota,3F2TA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Uncharacterised protein family (UPF0147)	-	-	-	ko:K09721	-	-	-	-	ko00000	-	-	-	UPF0147
LZS1_k127_4389023_9	439481.Aboo_0646	2.863e-21	96.0	COG1522@1|root,arCOG01580@2157|Archaea,2Y746@28890|Euryarchaeota,3F3D8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
LZS1_k127_4389023_13	673860.AciM339_0164	2.312e-15	76.0	arCOG05368@1|root,arCOG05368@2157|Archaea,2Y1EG@28890|Euryarchaeota,3F2W6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4389023_0	673860.AciM339_0894	6.629e-255	811.0	COG0060@1|root,arCOG00807@2157|Archaea,2XTIX@28890|Euryarchaeota,3F2FG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
LZS1_k127_4412166_0	453591.Igni_0623	1.078e-60	216.0	COG0381@1|root,arCOG01392@2157|Archaea,2XQ7Q@28889|Crenarchaeota	28889|Crenarchaeota	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS1_k127_4412166_1	118168.MC7420_7325	1.318e-08	65.0	COG0438@1|root,COG0438@2|Bacteria,1G8NA@1117|Cyanobacteria,1HENG@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
LZS1_k127_4418841_6	673860.AciM339_0367	1.041e-28	119.0	COG1522@1|root,arCOG01580@2157|Archaea,2XYWZ@28890|Euryarchaeota,3F2W1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
LZS1_k127_4418841_4	304371.MCP_0824	6.572e-69	241.0	COG4912@1|root,arCOG05122@2157|Archaea,2Y8HF@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
LZS1_k127_4418841_2	1054217.TALC_01537	7.174e-118	393.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y85G@28890|Euryarchaeota,242ID@183967|Thermoplasmata	28890|Euryarchaeota	C	4Fe-4S dicluster domain	hdrD	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
LZS1_k127_4418841_9	579137.Metvu_0200	3.06e-24	112.0	COG1763@1|root,arCOG00532@2157|Archaea,2XVAX@28890|Euryarchaeota,23QC4@183939|Methanococci	183939|Methanococci	H	PFAM molybdopterin-guanine dinucleotide biosynthesis MobB region	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	FeS,MobB
LZS1_k127_4418841_0	797304.Natgr_0818	7.88e-155	508.0	COG1032@1|root,arCOG01364@2157|Archaea,2XVND@28890|Euryarchaeota	28890|Euryarchaeota	C	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS1_k127_4418841_8	1054217.TALC_00209	6.602e-27	113.0	COG0838@1|root,arCOG01557@2157|Archaea,2XX2K@28890|Euryarchaeota	28890|Euryarchaeota	C	NADH ubiquinone oxidoreductase subunit 3 (Chain a)	nuoA	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114	1.5.98.3,1.6.5.3	ko:K00330,ko:K22158	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	iAF692.Mbar_A3412	Oxidored_q4
LZS1_k127_4418841_5	1054217.TALC_00210	3.057e-64	231.0	COG0377@1|root,arCOG01554@2157|Archaea,2XTP1@28890|Euryarchaeota,241SV@183967|Thermoplasmata	183967|Thermoplasmata	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.5.98.3,1.6.5.3	ko:K00331,ko:K22159	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	Oxidored_q6
LZS1_k127_4418841_7	387631.Asulf_01801	2.331e-27	117.0	COG0852@1|root,arCOG01551@2157|Archaea,2XZK1@28890|Euryarchaeota	28890|Euryarchaeota	C	NADH ubiquinone oxidoreductase 27 kD subunit	-	-	1.5.98.3,1.6.5.3	ko:K00332,ko:K22160	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	Complex1_30kDa
LZS1_k127_4418841_1	1054217.TALC_00212	5.74e-126	414.0	COG0649@1|root,arCOG01548@2157|Archaea,2XTWF@28890|Euryarchaeota,241MP@183967|Thermoplasmata	183967|Thermoplasmata	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
LZS1_k127_4418841_3	644966.Tmar_0311	1.202e-81	286.0	COG1005@1|root,COG1005@2|Bacteria,1TQNU@1239|Firmicutes,25E6Z@186801|Clostridia,3WDJU@538999|Clostridiales incertae sedis	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS1_k127_4427695_7	632335.Calkr_1457	7.29e-26	115.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,42F6A@68295|Thermoanaerobacterales	186801|Clostridia	E	Histidine biosynthesis bifunctional protein hisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
LZS1_k127_4427695_0	453591.Igni_0773	2.528e-96	323.0	COG0107@1|root,arCOG00617@2157|Archaea,2XQ5E@28889|Crenarchaeota	28889|Crenarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS1_k127_4427695_4	1054217.TALC_00545	1.01e-55	200.0	COG0131@1|root,arCOG04398@2157|Archaea,2XT2K@28890|Euryarchaeota,242GZ@183967|Thermoplasmata	183967|Thermoplasmata	E	Imidazoleglycerol-phosphate dehydratase	-	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
LZS1_k127_4427695_3	243232.MJ_1532	7.505e-57	211.0	COG0106@1|root,arCOG00618@2157|Archaea,2XSUF@28890|Euryarchaeota,23QJK@183939|Methanococci	183939|Methanococci	E	TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS1_k127_4427695_6	1236689.MMALV_04990	1.176e-46	188.0	COG0118@1|root,arCOG00089@2157|Archaea,2XTJ7@28890|Euryarchaeota	28890|Euryarchaeota	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS1_k127_4427695_5	1054217.TALC_00550	3.609e-55	211.0	COG0079@1|root,arCOG04273@2157|Archaea,2XTFZ@28890|Euryarchaeota,242D6@183967|Thermoplasmata	183967|Thermoplasmata	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_4427695_1	349163.Acry_2693	4.019e-89	309.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,2JPGF@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
LZS1_k127_4427695_2	378806.STAUR_4686	7.781e-77	268.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WIY9@28221|Deltaproteobacteria,2YV4H@29|Myxococcales	28221|Deltaproteobacteria	F	HisG, C-terminal domain	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
LZS1_k127_4427695_8	1236689.MMALV_12690	3.403e-11	64.0	COG4023@1|root,arCOG02957@2157|Archaea,2Y1AH@28890|Euryarchaeota,3F2U9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	but it may be involved in stabilization of the trimeric complex	secG	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
LZS1_k127_4430586_0	1128421.JAGA01000003_gene3053	6.821e-50	186.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg,dCache_1
LZS1_k127_4475017_1	1304874.JAFY01000002_gene574	7.646e-58	214.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_4475017_0	1304874.JAFY01000002_gene577	1.504e-71	260.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_4475017_2	391623.TERMP_01830	4.268e-42	163.0	COG1522@1|root,arCOG01580@2157|Archaea,2XX9F@28890|Euryarchaeota,243Z9@183968|Thermococci	183968|Thermococci	K	transcription regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
LZS1_k127_4475017_3	573061.Clocel_1595	2.193e-24	109.0	COG0017@1|root,COG0017@2|Bacteria,1UFEI@1239|Firmicutes,24EYB@186801|Clostridia,36GED@31979|Clostridiaceae	186801|Clostridia	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2
LZS1_k127_4475052_2	573061.Clocel_1595	4.595e-25	111.0	COG0017@1|root,COG0017@2|Bacteria,1UFEI@1239|Firmicutes,24EYB@186801|Clostridia,36GED@31979|Clostridiaceae	186801|Clostridia	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2
LZS1_k127_4475052_1	1042877.GQS_07345	7.908e-43	163.0	COG1522@1|root,arCOG01580@2157|Archaea,2XX9F@28890|Euryarchaeota,243Z9@183968|Thermococci	183968|Thermococci	K	transcription regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
LZS1_k127_4475052_0	1304874.JAFY01000002_gene577	1.735e-70	257.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_4478188_4	1173028.ANKO01000065_gene5617	1.17e-39	171.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H6WA@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_16,TPR_2,TPR_8
LZS1_k127_4478188_6	502025.Hoch_5820	0.0004918	54.0	COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
LZS1_k127_4478188_3	1499967.BAYZ01000080_gene896	6.598e-45	168.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red,Flavodoxin_1,Flavodoxin_5
LZS1_k127_4478188_0	292459.STH1872	1.466e-127	419.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia	186801|Clostridia	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_4478188_1	1183377.Py04_1102	2.519e-95	324.0	COG1063@1|root,arCOG01459@2157|Archaea,2XT8W@28890|Euryarchaeota,2438B@183968|Thermococci	183968|Thermococci	E	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008743,GO:0009066,GO:0009987,GO:0016043,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS1_k127_4478188_2	877455.Metbo_1667	2.478e-74	267.0	COG0595@1|root,arCOG00547@2157|Archaea,2XTIB@28890|Euryarchaeota,23PHA@183925|Methanobacteria	183925|Methanobacteria	J	PFAM RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B_2,RMMBL
LZS1_k127_4478188_5	765912.Thimo_3651	1.324e-06	58.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1WWPE@135613|Chromatiales	135613|Chromatiales	G	HAD-superfamily hydrolase, subfamily IA, variant 3	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS1_k127_4479349_0	1236689.MMALV_15350	6.375e-51	187.0	COG1094@1|root,arCOG04150@2157|Archaea,2XUHX@28890|Euryarchaeota,3F2NS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	K homology RNA-binding domain	dim2	-	-	ko:K06961	-	-	-	-	ko00000,ko03009	-	-	-	KH_1
LZS1_k127_4479349_1	410358.Mlab_1567	2.025e-12	72.0	COG1258@1|root,arCOG01015@2157|Archaea,2XTTX@28890|Euryarchaeota,2N98Y@224756|Methanomicrobia	224756|Methanomicrobia	J	Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs	pus10	-	5.4.99.25	ko:K07583	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP
LZS1_k127_4496037_2	439481.Aboo_0510	2.178e-08	64.0	arCOG02206@1|root,arCOG02206@2157|Archaea,2Y10D@28890|Euryarchaeota,3F34Z@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	ribosomal small subunit binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4496037_0	673860.AciM339_0533	1.582e-100	342.0	COG1746@1|root,arCOG04249@2157|Archaea,2XT5J@28890|Euryarchaeota,3F2HM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K07558	-	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko01000,ko03016	-	-	-	NTP_transf_2,tRNA_NucTransf2
LZS1_k127_4496037_1	439481.Aboo_0810	1.911e-92	312.0	COG1235@1|root,arCOG00499@2157|Archaea,2XT48@28890|Euryarchaeota,3F2JB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS1_k127_4529880_1	1385519.N801_07615	9.377e-13	68.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria,4FGJ4@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4529880_0	1236689.MMALV_15590	1.788e-67	241.0	COG0608@1|root,arCOG00427@2157|Archaea,2XW5A@28890|Euryarchaeota,3F2M1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHH,DHHA1
LZS1_k127_4529966_4	1385519.N801_07615	9.377e-13	68.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria,4FGJ4@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4529966_6	929713.NIASO_04475	0.0001869	55.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,4NGKT@976|Bacteroidetes,1IW42@117747|Sphingobacteriia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
LZS1_k127_4529966_3	5970.XP_009160885.1	1.638e-16	89.0	COG0500@1|root,KOG1269@2759|Eukaryota,38FGK@33154|Opisthokonta,3NYCG@4751|Fungi,3QX15@4890|Ascomycota,20SQ0@147545|Eurotiomycetes	4751|Fungi	I	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS1_k127_4529966_0	926569.ANT_15720	4.044e-104	364.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
LZS1_k127_4529966_1	1236689.MMALV_15590	1.788e-67	241.0	COG0608@1|root,arCOG00427@2157|Archaea,2XW5A@28890|Euryarchaeota,3F2M1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DHHA1 domain	-	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHH,DHHA1
LZS1_k127_4531380_0	1118054.CAGW01000101_gene4724	1.47e-142	459.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HV0C@91061|Bacilli,271MY@186822|Paenibacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS1_k127_4550252_3	1054217.TALC_01497	6.224e-11	63.0	COG1383@1|root,arCOG01885@2157|Archaea,2Y07I@28890|Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS17 family	rps17e	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02962	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17e
LZS1_k127_4550252_0	1379698.RBG1_1C00001G0603	3.394e-107	361.0	COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS1_k127_4550252_1	1379698.RBG1_1C00001G0602	2.779e-91	309.0	COG0842@1|root,COG0842@2|Bacteria,2NQCU@2323|unclassified Bacteria	2|Bacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS1_k127_4550252_2	926569.ANT_06940	8.688e-68	252.0	COG0842@1|root,COG0842@2|Bacteria,2G8MV@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS1_k127_4560880_3	690850.Desaf_0794	2.441e-65	234.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2M7VR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
LZS1_k127_4560880_2	351160.RCIX2034	1.563e-74	256.0	COG1394@1|root,arCOG04101@2157|Archaea,2XTQ5@28890|Euryarchaeota,2N9IG@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0384	ATP-synt_D
LZS1_k127_4560880_1	351160.RCIX2032	1.067e-240	749.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,2N97D@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS1_k127_4560880_0	1236689.MMALV_00110	2.885e-254	794.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,3F2G5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
LZS1_k127_459727_1	1229780.BN381_310029	0.0001707	49.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,3UX9I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS1_k127_459727_0	1227484.C471_10941	1.262e-16	93.0	COG0577@1|root,arCOG07560@1|root,arCOG02312@2157|Archaea,arCOG07560@2157|Archaea,2XTCP@28890|Euryarchaeota,23UG6@183963|Halobacteria	183963|Halobacteria	V	ABC-type antimicrobial peptide transport system, permease component	lolC	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS1_k127_469865_8	673860.AciM339_0394	3.175e-19	100.0	arCOG05363@1|root,arCOG05363@2157|Archaea,2Y07M@28890|Euryarchaeota,3F2V9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
LZS1_k127_469865_5	999630.TUZN_1610	1.318e-28	121.0	COG1437@1|root,arCOG01723@2157|Archaea,2XQWN@28889|Crenarchaeota	28889|Crenarchaeota	F	adenylyl cyclase CyaB	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
LZS1_k127_469865_7	439481.Aboo_0215	2.543e-22	101.0	COG1719@1|root,arCOG01688@2157|Archaea	2157|Archaea	K	PFAM 4-vinyl reductase, 4VR	-	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	DUF2507,V4R
LZS1_k127_469865_3	439481.Aboo_0444	5.794e-40	156.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y4UK@28890|Euryarchaeota,3F2ZZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	GvpD gas vesicle protein	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_469865_9	351160.RCIX981	4.603e-17	93.0	COG0642@1|root,arCOG03799@1|root,arCOG06536@1|root,arCOG03799@2157|Archaea,arCOG06192@2157|Archaea,arCOG06536@2157|Archaea,2Y7UB@28890|Euryarchaeota,2NBMX@224756|Methanomicrobia	28890|Euryarchaeota	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_9,Response_reg
LZS1_k127_469865_4	673860.AciM339_1365	4.236e-39	156.0	COG2109@1|root,arCOG04678@2157|Archaea,2XUZ3@28890|Euryarchaeota,3F2NV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	cobA	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
LZS1_k127_469865_2	673860.AciM339_0324	5.106e-43	173.0	COG0640@1|root,arCOG03408@1|root,arCOG01683@2157|Archaea,arCOG03409@2157|Archaea	2157|Archaea	K	PFAM Archaeal ATPase	birA	-	6.3.4.15	ko:K03524,ko:K06921	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	AAA_16,ATPase_2,BPL_C,BPL_LplA_LipB,HTH_11,TPR_12
LZS1_k127_469865_10	1237149.C900_01735	1.903e-07	65.0	COG2931@1|root,COG2931@2|Bacteria,4NFV5@976|Bacteroidetes,47MFU@768503|Cytophagia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
LZS1_k127_469865_6	673860.AciM339_1283	1.001e-23	115.0	arCOG07412@1|root,arCOG07412@2157|Archaea,2Y0S5@28890|Euryarchaeota,3F2T8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_469865_1	1236689.MMALV_00210	3.315e-85	294.0	COG1395@1|root,arCOG04152@2157|Archaea,2XTMG@28890|Euryarchaeota,3F2M0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07728	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
LZS1_k127_469865_0	439481.Aboo_0405	3.489e-228	714.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,3F39E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
LZS1_k127_4712108_10	694440.JOMF01000006_gene553	6.778e-64	227.0	COG0527@1|root,arCOG00861@2157|Archaea,2XTJ0@28890|Euryarchaeota,2N91C@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
LZS1_k127_4712108_0	1236689.MMALV_03290	1.191e-188	604.0	COG0129@1|root,arCOG04045@2157|Archaea,2XSW2@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2069	ILVD_EDD
LZS1_k127_4712108_18	673860.AciM339_0610	9.786e-14	84.0	arCOG03799@1|root,arCOG03799@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF835
LZS1_k127_4712108_13	383372.Rcas_2277	4.317e-46	182.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
LZS1_k127_4712108_7	926550.CLDAP_21770	1.819e-73	258.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
LZS1_k127_4712108_2	386456.JQKN01000014_gene3107	3.345e-167	542.0	COG0119@1|root,arCOG02092@2157|Archaea,2XSZJ@28890|Euryarchaeota,23NPS@183925|Methanobacteria	183925|Methanobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
LZS1_k127_4712108_3	1236689.MMALV_05870	6.989e-160	514.0	COG0065@1|root,arCOG01698@2157|Archaea,2XTWH@28890|Euryarchaeota,3F2G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
LZS1_k127_4712108_12	1236689.MMALV_05880	1.399e-49	183.0	COG0066@1|root,arCOG02230@2157|Archaea,2XTXJ@28890|Euryarchaeota,3F2QD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
LZS1_k127_4712108_4	269797.Mbar_A1339	1.801e-115	392.0	COG0473@1|root,arCOG01163@2157|Archaea,2XT99@28890|Euryarchaeota,2N918@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM isocitrate isopropylmalate dehydrogenase	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS1_k127_4712108_19	457415.HMPREF1006_02178	1.677e-09	64.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ACT
LZS1_k127_4712108_5	1041930.Mtc_1102	1.461e-86	299.0	COG0598@1|root,arCOG02265@2157|Archaea,2Y2PC@28890|Euryarchaeota,2NAPG@224756|Methanomicrobia	224756|Methanomicrobia	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS1_k127_4712108_16	933801.Ahos_1461	6.061e-26	124.0	COG0441@1|root,arCOG00401@2157|Archaea,2XQ02@28889|Crenarchaeota	28889|Crenarchaeota	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr)	thrS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b
LZS1_k127_4712108_1	1041930.Mtc_0248	4.881e-173	561.0	COG0441@1|root,arCOG00401@2157|Archaea,2XTFI@28890|Euryarchaeota,2N9FW@224756|Methanomicrobia	224756|Methanomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-Thr_ED,tRNA-synt_2b,tRNA_SAD
LZS1_k127_4712108_9	673860.AciM339_1056	1.315e-65	234.0	COG0602@1|root,arCOG02173@2157|Archaea,2XUSP@28890|Euryarchaeota,3F2KS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS1_k127_4712108_8	673860.AciM339_0378	1.312e-72	251.0	COG0603@1|root,arCOG00039@2157|Archaea,2XTS7@28890|Euryarchaeota,3F2JU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
LZS1_k127_4712108_15	1054217.TALC_00448	4.619e-37	145.0	COG0720@1|root,arCOG02172@2157|Archaea,2XXFY@28890|Euryarchaeota,241WN@183967|Thermoplasmata	183967|Thermoplasmata	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
LZS1_k127_4712108_14	1094980.Mpsy_2836	1.973e-43	168.0	COG4002@1|root,arCOG00854@2157|Archaea,2XVHH@28890|Euryarchaeota,2NBJX@224756|Methanomicrobia	224756|Methanomicrobia	S	methyltransferase activity	mtxX	-	-	-	-	-	-	-	-	-	-	-	PTA_PTB
LZS1_k127_4712108_6	192952.MM_1877	1.167e-79	276.0	COG1736@1|root,arCOG04112@2157|Archaea,2XSY5@28890|Euryarchaeota,2N9AT@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM Diphthamide synthesis DPH2 protein	dph2	-	2.5.1.108	ko:K07561	-	-	R10455	RC00021,RC03180	ko00000,ko01000,ko03012	-	-	-	Diphthamide_syn
LZS1_k127_4712108_11	1236689.MMALV_03700	7.147e-57	203.0	COG0197@1|root,arCOG04113@2157|Archaea,2XTHT@28890|Euryarchaeota,3F2P8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the universal ribosomal protein uL16 family	rpl10e	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02866	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
LZS1_k127_4712108_17	410358.Mlab_1485	3.176e-17	85.0	COG2023@1|root,arCOG04345@2157|Archaea,2XYX0@28890|Euryarchaeota	28890|Euryarchaeota	J	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends	rnp4	GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904	3.1.26.5	ko:K03540	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rpr2
LZS1_k127_4712108_20	445971.ANASTE_01855	2.424e-07	55.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,25WUD@186806|Eubacteriaceae	186801|Clostridia	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
LZS1_k127_4712108_21	1230457.C476_00327	0.0001546	46.0	COG0172@1|root,arCOG00403@2157|Archaea,2XTGA@28890|Euryarchaeota,23STG@183963|Halobacteria	183963|Halobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
LZS1_k127_4747402_0	882082.SaccyDRAFT_2428	2.223e-54	214.0	COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,4DYSP@85010|Pseudonocardiales	201174|Actinobacteria	EP	ABC-type dipeptide oligopeptide nickel transport system, permease component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS1_k127_4747402_1	760568.Desku_0147	7.168e-39	149.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,261Z5@186807|Peptococcaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
LZS1_k127_4778905_1	351160.RCIX2598	1.053e-49	196.0	arCOG04521@1|root,arCOG04521@2157|Archaea,2XUMG@28890|Euryarchaeota,2NAW2@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4778905_0	368407.Memar_2482	3.077e-77	265.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT2Y@28890|Euryarchaeota,2N9GE@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_4778905_3	673860.AciM339_0651	3.579e-24	105.0	COG3388@1|root,arCOG01345@2157|Archaea,2XXVY@28890|Euryarchaeota,3F2T1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4778905_2	1343739.PAP_08680	4.904e-41	164.0	arCOG11292@1|root,arCOG11292@2157|Archaea,2Y3FT@28890|Euryarchaeota,2443S@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4902583_2	351160.RRC219	1.017e-91	306.0	COG0180@1|root,arCOG01887@2157|Archaea,2XSVC@28890|Euryarchaeota,2N997@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF692.Mbar_A1374	tRNA-synt_1b
LZS1_k127_4902583_3	351160.RCIX1987	5.264e-22	109.0	COG1720@1|root,arCOG00761@2157|Archaea,2XYZ5@28890|Euryarchaeota,2N9XJ@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
LZS1_k127_4902583_0	1236689.MMALV_13960	4.271e-152	496.0	COG0016@1|root,arCOG00410@2157|Archaea,2XSTK@28890|Euryarchaeota,3F2II@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2d
LZS1_k127_4902583_1	926569.ANT_06740	7.782e-112	375.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1
LZS1_k127_4902583_4	103733.JNYO01000016_gene3326	2.019e-06	60.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
LZS1_k127_5095761_0	706587.Desti_2950	2.619e-238	755.0	COG0067@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0070@2|Bacteria,1NZ4D@1224|Proteobacteria,43B3T@68525|delta/epsilon subdivisions,2X6HR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GXGXG motif	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,GXGXG
LZS1_k127_5095761_4	556261.HMPREF0240_02721	2.55e-09	61.0	COG2002@1|root,COG2002@2|Bacteria,1VDAQ@1239|Firmicutes,24RPD@186801|Clostridia,36VJA@31979|Clostridiaceae	186801|Clostridia	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
LZS1_k127_5095761_1	368407.Memar_0243	3.529e-126	413.0	COG1131@1|root,arCOG00196@2157|Archaea,2Y7M5@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS1_k127_5095761_2	368407.Memar_0242	2.826e-94	322.0	COG0842@1|root,arCOG01467@2157|Archaea,2XU41@28890|Euryarchaeota	28890|Euryarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS1_k127_5095761_3	1235835.C814_00685	1.635e-17	85.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,3WGGC@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	nfnA	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
LZS1_k127_5117087_4	572544.Ilyop_1231	7.589e-41	163.0	COG1171@1|root,COG1171@2|Bacteria,378K1@32066|Fusobacteria	32066|Fusobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
LZS1_k127_5117087_2	1123023.JIAI01000004_gene8148	1.756e-86	298.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4DZJY@85010|Pseudonocardiales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	ocd	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
LZS1_k127_5117087_7	994573.T472_0207905	3.704e-11	70.0	COG0716@1|root,COG0716@2|Bacteria,1VND7@1239|Firmicutes	1239|Firmicutes	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
LZS1_k127_5117087_3	1121406.JAEX01000005_gene3046	2.406e-52	197.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,42PPN@68525|delta/epsilon subdivisions,2WK8S@28221|Deltaproteobacteria,2M7WI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
LZS1_k127_5117087_1	439235.Dalk_0051	4.94e-89	302.0	COG1145@1|root,COG1145@2|Bacteria	439235.Dalk_0051|-	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5117087_5	765420.OSCT_0887	1.55e-26	123.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
LZS1_k127_5117087_6	330779.Saci_2097	9.63e-24	108.0	COG0477@1|root,arCOG00132@2157|Archaea,2XQC5@28889|Crenarchaeota	28889|Crenarchaeota	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_5127557_7	1054217.TALC_00332	7.049e-25	106.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
LZS1_k127_5127557_3	1236689.MMALV_03040	1.25e-65	227.0	COG1908@1|root,arCOG02475@2157|Archaea,2XY1E@28890|Euryarchaeota,3F2PR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Methyl-viologen-reducing hydrogenase, delta subunit	mvhD-2	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
LZS1_k127_5127557_9	335543.Sfum_1180	4.155e-09	62.0	COG1908@1|root,COG1908@2|Bacteria,1RDMH@1224|Proteobacteria,42RX1@68525|delta/epsilon subdivisions,2WNT8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CK	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD,HTH_5
LZS1_k127_5127557_2	1236689.MMALV_03050	6.269e-107	356.0	COG1941@1|root,arCOG02472@2157|Archaea,2XZ11@28890|Euryarchaeota,3F2V2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hydD	-	1.12.1.3,1.12.1.5,1.8.98.5	ko:K14128,ko:K17994	ko00680,ko00920,map00680,map00920	-	R00019,R10390,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
LZS1_k127_5127557_0	477974.Daud_1651	2.525e-188	600.0	COG3259@1|root,COG3259@2|Bacteria,1UZNV@1239|Firmicutes,24F0H@186801|Clostridia,2644W@186807|Peptococcaceae	186801|Clostridia	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
LZS1_k127_5127557_6	909663.KI867150_gene2060	3.818e-26	113.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WP4D@28221|Deltaproteobacteria,2MQQW@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Hydrogenase maturation protease	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
LZS1_k127_5127557_1	1054217.TALC_01492	1.231e-114	380.0	COG0309@1|root,arCOG00636@2157|Archaea,2XTAH@28890|Euryarchaeota,241W7@183967|Thermoplasmata	183967|Thermoplasmata	O	AIR synthase related protein, C-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
LZS1_k127_5127557_5	351160.RCIX886	4.171e-27	119.0	COG0746@1|root,arCOG01872@2157|Archaea,2XWJR@28890|Euryarchaeota,2N9W7@224756|Methanomicrobia	224756|Methanomicrobia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS1_k127_5127557_4	1455608.JDTH01000006_gene2649	8.132e-35	143.0	arCOG04662@1|root,arCOG04663@1|root,arCOG04662@2157|Archaea,arCOG04663@2157|Archaea,2XU93@28890|Euryarchaeota,23TQ8@183963|Halobacteria	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5127557_8	662479.C440_10833	1.201e-11	69.0	arCOG04663@1|root,arCOG04663@2157|Archaea,2XWWP@28890|Euryarchaeota,23V7M@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5137330_2	673860.AciM339_0553	1.341e-16	79.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
LZS1_k127_5137330_3	1236689.MMALV_00350	3.615e-12	70.0	arCOG15031@1|root,arCOG15031@2157|Archaea,2Y4G8@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5137330_0	579137.Metvu_1328	3.151e-51	191.0	COG0041@1|root,arCOG02464@2157|Archaea,2XU0P@28890|Euryarchaeota,23QSX@183939|Methanococci	183939|Methanococci	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
LZS1_k127_5137330_1	439481.Aboo_0486	5.476e-19	87.0	COG0519@1|root,arCOG00085@2157|Archaea,2XT82@28890|Euryarchaeota,3F2I1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaAB	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iAF692.Mbar_A1178	GMP_synt_C,NAD_synthase
LZS1_k127_5153493_0	673860.AciM339_1459	5.559e-81	273.0	COG0459@1|root,arCOG01257@2157|Archaea,2XUDQ@28890|Euryarchaeota,3F2FS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	TCP-1/cpn60 chaperonin family	thsA	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077	-	ko:K22447	-	-	-	-	ko00000,ko03110	-	-	-	Cpn60_TCP1
LZS1_k127_5153493_2	351160.LRC472	9.012e-26	114.0	COG0576@1|root,arCOG04772@2157|Archaea,2XUCA@28890|Euryarchaeota,2NA0X@224756|Methanomicrobia	224756|Methanomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS1_k127_5153493_1	247490.KSU1_C1370	1.893e-63	219.0	COG0443@1|root,COG0443@2|Bacteria,2IWWS@203682|Planctomycetes	203682|Planctomycetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS1_k127_5165841_1	1463920.JOGB01000024_gene3708	0.0001367	54.0	COG1670@1|root,COG4927@1|root,COG1670@2|Bacteria,COG4927@2|Bacteria,2I90W@201174|Actinobacteria	201174|Actinobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
LZS1_k127_5165841_0	644282.Deba_0799	3.075e-131	422.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,42MIN@68525|delta/epsilon subdivisions,2WJC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	serves to protect cells from the toxic effects of hydrogen peroxide	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
LZS1_k127_5167971_1	1183377.Py04_0826	6.897e-78	269.0	COG1831@1|root,arCOG00893@2157|Archaea,2XTX7@28890|Euryarchaeota,243FU@183968|Thermococci	183968|Thermococci	S	TatD related DNase	-	-	-	ko:K07049	-	-	-	-	ko00000	-	-	-	TatD_DNase
LZS1_k127_5167971_0	1054217.TALC_01013	6.284e-80	269.0	COG2101@1|root,arCOG01764@2157|Archaea,2XTTR@28890|Euryarchaeota,241NQ@183967|Thermoplasmata	183967|Thermoplasmata	K	General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation	tbp	-	-	ko:K03120	ko03022,ko05016,ko05165,ko05166,ko05168,ko05169,ko05203,map03022,map05016,map05165,map05166,map05168,map05169,map05203	-	-	-	ko00000,ko00001,ko03000,ko03021	-	-	-	TBP
LZS1_k127_516902_1	1236689.MMALV_13680	4.403e-28	128.0	COG0583@1|root,arCOG00225@2157|Archaea,2XYM3@28890|Euryarchaeota	28890|Euryarchaeota	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1
LZS1_k127_516902_0	868131.MSWAN_0582	1.982e-43	162.0	COG0842@1|root,arCOG01463@2157|Archaea,2XWB7@28890|Euryarchaeota,23PY9@183925|Methanobacteria	183925|Methanobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS1_k127_5187117_4	926561.KB900618_gene56	1.056e-48	181.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,3WB2P@53433|Halanaerobiales	186801|Clostridia	C	PFAM Iron-containing alcohol dehydrogenase	-	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
LZS1_k127_5187117_2	1033806.HTIA_0366	4.987e-56	205.0	COG0013@1|root,arCOG01254@2157|Archaea,2XTZC@28890|Euryarchaeota,23UTP@183963|Halobacteria	183963|Halobacteria	J	metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
LZS1_k127_5187117_1	706587.Desti_5348	4.576e-65	237.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42R1T@68525|delta/epsilon subdivisions,2WN88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cysteine-rich domain	-	-	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
LZS1_k127_5187117_3	797299.HALLA_12770	6.972e-52	202.0	COG0277@1|root,arCOG00337@2157|Archaea,2XT5C@28890|Euryarchaeota,23TIK@183963|Halobacteria	183963|Halobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS1_k127_5187117_0	304371.MCP_2869	2.021e-69	246.0	COG3294@1|root,arCOG04230@2157|Archaea,2XURZ@28890|Euryarchaeota	28890|Euryarchaeota	S	Phosphohydrolase	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
LZS1_k127_5187117_5	1321773.HMPREF9069_00118	2.219e-09	68.0	COG2510@1|root,COG2510@2|Bacteria,2GPBF@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_5204838_4	1054217.TALC_01161	2.204e-15	86.0	COG1836@1|root,arCOG02245@2157|Archaea,2XTBR@28890|Euryarchaeota,241UU@183967|Thermoplasmata	183967|Thermoplasmata	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
LZS1_k127_5204838_5	211165.AJLN01000107_gene5633	4.552e-08	68.0	COG2885@1|root,COG2885@2|Bacteria,1G2YF@1117|Cyanobacteria,1JGWQ@1189|Stigonemataceae	1117|Cyanobacteria	M	OmpA family	-	-	-	ko:K02557,ko:K03286	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1,1.B.6	-	-	OmpA
LZS1_k127_5204838_1	251221.35214019	9.909e-32	146.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
LZS1_k127_5204838_3	439481.Aboo_0815	8.346e-26	122.0	COG1277@1|root,arCOG03689@2157|Archaea,2Y0MI@28890|Euryarchaeota,3F2VX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
LZS1_k127_5204838_0	1236689.MMALV_14690	1.482e-83	288.0	COG1131@1|root,arCOG00196@2157|Archaea,2Y7KH@28890|Euryarchaeota	28890|Euryarchaeota	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_5204838_6	521011.Mpal_1939	2.94e-07	55.0	arCOG09483@1|root,arCOG09483@2157|Archaea	2157|Archaea	-	-	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
LZS1_k127_5204838_2	1236689.MMALV_12030	1.5e-27	115.0	COG0237@1|root,arCOG01045@2157|Archaea,2XWNJ@28890|Euryarchaeota,3F2R1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	AAA domain	coaE	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A0975	AAA_17,RNA_binding
LZS1_k127_5215184_0	118161.KB235922_gene3213	1.644e-142	466.0	COG0591@1|root,COG0591@2|Bacteria,1G3QJ@1117|Cyanobacteria,3VMKF@52604|Pleurocapsales	1117|Cyanobacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS1_k127_5215184_1	743719.PaelaDRAFT_0864	1.775e-18	92.0	COG0500@1|root,COG2226@2|Bacteria,1U5XV@1239|Firmicutes,4HBHC@91061|Bacilli,26ST9@186822|Paenibacillaceae	91061|Bacilli	Q	catalyzes the formation of a number of methylated intermediates from arsenite and SAM producing trimethylarsine	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
LZS1_k127_5230380_0	1459636.NTE_02631	1.987e-143	463.0	COG0334@1|root,arCOG01352@2157|Archaea,41S7T@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS1_k127_5230380_4	1236689.MMALV_04040	4.068e-28	120.0	arCOG04964@1|root,arCOG04964@2157|Archaea,2XZQX@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5230380_2	880073.Calab_1228	1.989e-69	242.0	COG3634@1|root,COG3634@2|Bacteria,2NPR2@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
LZS1_k127_5230380_3	351607.Acel_0042	1.52e-32	133.0	COG1765@1|root,COG1765@2|Bacteria,2HA74@201174|Actinobacteria	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
LZS1_k127_5230380_1	386456.JQKN01000011_gene732	8.633e-128	420.0	COG1027@1|root,arCOG01750@2157|Archaea,2Y84P@28890|Euryarchaeota	28890|Euryarchaeota	E	Fumarase C C-terminus	-	-	4.2.1.2,4.3.1.1	ko:K01679,ko:K01744	ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R00490,R01082	RC00316,RC00443,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS1_k127_5276005_0	1054217.TALC_01206	9.816e-135	442.0	COG0124@1|root,arCOG00404@2157|Archaea,2XSYX@28890|Euryarchaeota,241P5@183967|Thermoplasmata	183967|Thermoplasmata	J	histidyl-tRNA aminoacylation	hisS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
LZS1_k127_5276005_1	1236689.MMALV_08820	4.678e-82	289.0	COG1055@1|root,arCOG00238@2157|Archaea,2XVWR@28890|Euryarchaeota,3F2QA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	P	Bacterial Na+/H+ antiporter B (NhaB)	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB,CitMHS
LZS1_k127_5276005_2	1054217.TALC_01448	0.0001282	46.0	arCOG14617@1|root,arCOG14617@2157|Archaea,2Y5TW@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5280388_1	673860.AciM339_0006	4.038e-20	96.0	COG4962@1|root,arCOG01817@2157|Archaea,2XT4E@28890|Euryarchaeota,3F381@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Type II/IV secretion system protein	-	-	-	ko:K07332	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS1_k127_5280388_0	439481.Aboo_0005	2.407e-20	102.0	arCOG02911@1|root,arCOG02911@2157|Archaea,2Y701@28890|Euryarchaeota,3F31J@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	toxin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5300919_2	1236689.MMALV_02060	4.447e-44	170.0	COG1007@1|root,arCOG01540@2157|Archaea	2157|Archaea	C	NADH ubiquinone oxidoreductase subunit 2 (Chain N)	nuoN	-	1.5.98.3,1.6.5.3	ko:K00343,ko:K22169	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	iAF692.Mbar_A3401	Proton_antipo_M
LZS1_k127_5300919_1	192952.MM_2481	3.42e-117	394.0	COG1008@1|root,arCOG01538@2157|Archaea,2XTP0@28890|Euryarchaeota,2NAFX@224756|Methanomicrobia	224756|Methanomicrobia	C	Proton-conducting membrane transporter	-	-	1.5.98.3	ko:K22168	-	-	-	-	ko00000,ko01000	3.D.9.1	-	-	Proton_antipo_M
LZS1_k127_5300919_0	1236689.MMALV_02040	2.318e-180	585.0	COG1009@1|root,arCOG01539@2157|Archaea,2Y85E@28890|Euryarchaeota	28890|Euryarchaeota	C	Proton-conducting membrane transporter	-	-	-	ko:K05565,ko:K12137	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
LZS1_k127_5300919_4	1236689.MMALV_02030	8.425e-27	118.0	COG0713@1|root,arCOG03073@2157|Archaea,2XXW4@28890|Euryarchaeota	28890|Euryarchaeota	C	NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K)	nuoK	-	1.5.98.3,1.6.5.3	ko:K00340,ko:K22166	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	Oxidored_q2
LZS1_k127_5300919_5	1033734.CAET01000046_gene609	3.694e-12	73.0	COG0839@1|root,COG0839@2|Bacteria,1V48R@1239|Firmicutes,4HJAV@91061|Bacilli,1ZFW1@1386|Bacillus	91061|Bacilli	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
LZS1_k127_5300919_3	1236689.MMALV_02000	8.334e-36	147.0	COG1143@1|root,arCOG01543@2157|Archaea,2XTIJ@28890|Euryarchaeota,3F2WB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S dicluster domain	-	-	1.1.98.4,1.5.98.3,1.6.5.3	ko:K00338,ko:K14121,ko:K22164,ko:K22176	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.9.1	-	-	Fer4
LZS1_k127_5304855_0	1125863.JAFN01000001_gene2353	4.663e-23	113.0	COG1716@1|root,COG1716@2|Bacteria,1RGIT@1224|Proteobacteria,43BCI@68525|delta/epsilon subdivisions,2WQHE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
LZS1_k127_5304855_1	673860.AciM339_0490	2.61e-12	68.0	arCOG13525@1|root,arCOG13525@2157|Archaea,2Y72N@28890|Euryarchaeota,3F3A7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5318154_0	1313172.YM304_34050	8.455e-130	471.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	Cadherin,DUF11,GSu_C4xC__C2xCH,SdrD_B
LZS1_k127_5318154_1	994573.T472_0205120	1.831e-07	66.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1VIJZ@1239|Firmicutes	1239|Firmicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS1_k127_5331538_0	1041930.Mtc_0048	5.298e-151	491.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,2N9CA@224756|Methanomicrobia	224756|Methanomicrobia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
LZS1_k127_5331538_4	1223542.GM1_011_00090	4.782e-11	69.0	COG2867@1|root,COG2867@2|Bacteria,2I47G@201174|Actinobacteria,4GH8A@85026|Gordoniaceae	201174|Actinobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
LZS1_k127_5331538_3	1094980.Mpsy_2603	6.742e-18	84.0	COG2835@1|root,arCOG04124@2157|Archaea,2XZRS@28890|Euryarchaeota,2NA4S@224756|Methanomicrobia	224756|Methanomicrobia	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
LZS1_k127_5331538_1	673860.AciM339_0815	4.134e-82	284.0	COG0673@1|root,arCOG01622@2157|Archaea,2XTZY@28890|Euryarchaeota	28890|Euryarchaeota	S	Oxidoreductase domain protein	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS1_k127_5331538_2	304371.MCP_0863	6.793e-48	178.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,2NAID@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS1_k127_535045_6	1158050.KB895456_gene2119	3.012e-07	61.0	arCOG12322@1|root,32UYB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_535045_0	304371.MCP_2914	8.043e-110	391.0	COG1033@1|root,COG2409@1|root,arCOG02174@2157|Archaea,arCOG02175@2157|Archaea,2XVKJ@28890|Euryarchaeota	28890|Euryarchaeota	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
LZS1_k127_535045_2	1094980.Mpsy_1153	1.446e-23	110.0	COG1378@1|root,arCOG02038@2157|Archaea,2Y7FZ@28890|Euryarchaeota	28890|Euryarchaeota	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
LZS1_k127_535045_1	1463920.JOGB01000001_gene3407	2.421e-45	179.0	COG1748@1|root,COG1748@2|Bacteria,2GMQ1@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	lys1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
LZS1_k127_535045_4	410358.Mlab_0190	2.6e-18	85.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	-
LZS1_k127_535045_5	1151061.CAJY01000017_gene220	3.498e-16	84.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
LZS1_k127_535045_3	862751.SACTE_6500	1.227e-18	97.0	COG0454@1|root,COG0456@2|Bacteria,2GN6Q@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS1_k127_5351112_4	926562.Oweho_0461	1.014e-15	90.0	COG1721@1|root,COG1721@2|Bacteria,4NE10@976|Bacteroidetes,1HXIV@117743|Flavobacteriia,2PACR@246874|Cryomorphaceae	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS1_k127_5351112_3	33876.JNXY01000006_gene1193	9.333e-33	132.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DBN1@85008|Micromonosporales	201174|Actinobacteria	S	ATPase associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS1_k127_5351112_1	985053.VMUT_2331	2.189e-58	207.0	COG0714@1|root,arCOG00434@2157|Archaea,2XPMH@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS1_k127_5351112_0	1041930.Mtc_2327	4.348e-71	249.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XSXC@28890|Euryarchaeota,2N9K5@224756|Methanomicrobia	224756|Methanomicrobia	Q	Ribosomal protein L11 methyltransferase (PrmA)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
LZS1_k127_5351112_2	1449976.KALB_4319	7.197e-35	154.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4E0AJ@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_5357229_0	1236689.MMALV_07510	9.215e-75	255.0	COG1602@1|root,arCOG04269@2157|Archaea,2XTEQ@28890|Euryarchaeota,3F34R@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Archaeal Nre, N-terminal	nreA	-	-	-	-	-	-	-	-	-	-	-	Nre_C,Nre_N
LZS1_k127_5357229_1	1236689.MMALV_08990	1.443e-53	205.0	COG1533@1|root,arCOG01290@2157|Archaea,2XY2A@28890|Euryarchaeota,3F2Q3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS1_k127_5361318_1	673860.AciM339_1017	2.808e-94	313.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F31W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS1_k127_5361318_0	673860.AciM339_0142	1.944e-150	485.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F32D@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS1_k127_5361318_4	1236689.MMALV_00430	8.982e-14	75.0	COG2443@1|root,arCOG02204@2157|Archaea,2Y6IU@28890|Euryarchaeota,3F2UZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	TIGRFAM protein translocase SEC61 complex gamma subunit	-	-	-	ko:K07342	ko03060,ko04141,ko04145,ko05110,map03060,map04141,map04145,map05110	M00401	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.7,3.A.5.8,3.A.5.9	-	-	-
LZS1_k127_5361318_2	1236689.MMALV_00440	1.149e-59	217.0	COG0250@1|root,arCOG01920@2157|Archaea,2XWGQ@28890|Euryarchaeota,3F2RK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Transcription elongation factor Spt5	spt5	GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,Spt5-NGN
LZS1_k127_5361318_3	439481.Aboo_0863	1.429e-53	192.0	COG0080@1|root,arCOG04372@2157|Archaea,2XTJN@28890|Euryarchaeota,3F2N7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rpl11	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
LZS1_k127_5369629_25	523845.AQXV01000050_gene969	1.586e-15	79.0	arCOG05874@1|root,arCOG05874@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5369629_28	1236689.MMALV_08200	2.121e-06	58.0	arCOG01917@1|root,arCOG01917@2157|Archaea,2Y445@28890|Euryarchaeota	28890|Euryarchaeota	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
LZS1_k127_5369629_7	511051.CSE_08820	1.645e-86	300.0	COG1251@1|root,COG1251@2|Bacteria	2|Bacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363	1.6.3.4,1.7.1.15	ko:K00362,ko:K02192,ko:K22405	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Flavodoxin_1,Lactamase_B,Pyr_redox_2
LZS1_k127_5369629_1	386456.JQKN01000001_gene2123	1.009e-256	819.0	COG0013@1|root,arCOG01255@2157|Archaea,2XSXB@28890|Euryarchaeota,23NSY@183925|Methanobacteria	183925|Methanobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS1_k127_5369629_22	572546.Arcpr_1001	2.668e-35	142.0	COG1814@1|root,arCOG01091@2157|Archaea,2XVWH@28890|Euryarchaeota,2467J@183980|Archaeoglobi	183980|Archaeoglobi	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
LZS1_k127_5369629_23	1220534.B655_2178	1.071e-25	114.0	COG0864@1|root,arCOG01008@2157|Archaea,2XWHW@28890|Euryarchaeota,23PYE@183925|Methanobacteria	28890|Euryarchaeota	K	Ribbon-helix-helix protein, copG family	nikR1	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
LZS1_k127_5369629_19	357808.RoseRS_0174	1.145e-43	172.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi,376DK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
LZS1_k127_5369629_26	760568.Desku_0693	5.949e-15	84.0	COG0619@1|root,COG0619@2|Bacteria,1U6XW@1239|Firmicutes,24EV0@186801|Clostridia,261VA@186807|Peptococcaceae	186801|Clostridia	P	cobalt ABC transporter, inner membrane subunit CbiQ	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
LZS1_k127_5369629_14	1094980.Mpsy_1503	2.357e-68	243.0	COG1122@1|root,arCOG00203@2157|Archaea,2Y7N4@28890|Euryarchaeota	28890|Euryarchaeota	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	ecfA	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
LZS1_k127_5369629_17	1054217.TALC_00426	1.51e-51	188.0	COG0099@1|root,arCOG01722@2157|Archaea,2XWHE@28890|Euryarchaeota,241SD@183967|Thermoplasmata	183967|Thermoplasmata	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rps13	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
LZS1_k127_5369629_15	673860.AciM339_1559	9.516e-60	214.0	COG0522@1|root,arCOG04239@2157|Archaea,2XXYX@28890|Euryarchaeota,3F2KM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rps4	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
LZS1_k127_5369629_16	1236689.MMALV_03520	2.606e-58	205.0	COG0100@1|root,arCOG04240@2157|Archaea,2XX1S@28890|Euryarchaeota,3F2N2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ribosomal protein S11	rps11	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
LZS1_k127_5369629_11	1236689.MMALV_03530	3.122e-78	270.0	COG0202@1|root,arCOG04241@2157|Archaea,2XTQB@28890|Euryarchaeota,3F2KY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoD	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03047	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Fer4,RNA_pol_A_bac,RNA_pol_L
LZS1_k127_5369629_0	673860.AciM339_1497	0.0	1168.0	COG1933@1|root,arCOG04447@2157|Archaea,2XU5S@28890|Euryarchaeota,3F2HV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polC	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.7.7.7	ko:K02322	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	Intein_splicing,LAGLIDADG_3,PolC_DP2
LZS1_k127_5369629_30	368408.Tpen_1010	0.0001281	50.0	arCOG03714@1|root,arCOG03714@2157|Archaea,2XQDX@28889|Crenarchaeota	28889|Crenarchaeota	F	ATP cone domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-cone
LZS1_k127_5369629_6	1054217.TALC_00431	5.619e-91	310.0	COG1084@1|root,arCOG00352@2157|Archaea,2XU5R@28890|Euryarchaeota,241NE@183967|Thermoplasmata	183967|Thermoplasmata	S	Nucleolar GTP-binding protein 1 (NOG1)	-	-	-	ko:K06943	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	MMR_HSR1,NOG1
LZS1_k127_5369629_2	1121468.AUBR01000045_gene1800	5.078e-252	788.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,42FI5@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
LZS1_k127_5369629_13	439481.Aboo_1086	2.094e-73	254.0	COG1051@1|root,COG2005@1|root,arCOG00223@2157|Archaea,arCOG01075@2157|Archaea,2XXS4@28890|Euryarchaeota,3F39U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS1_k127_5369629_18	304371.MCP_2733	3.596e-46	175.0	arCOG07446@1|root,arCOG07446@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5369629_9	304371.MCP_2734	4.825e-82	284.0	arCOG03776@1|root,arCOG03776@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TF_Zn_Ribbon
LZS1_k127_5369629_8	304371.MCP_2735	7.565e-85	288.0	arCOG03776@1|root,arCOG03776@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TF_Zn_Ribbon
LZS1_k127_5369629_3	351160.RCIX132	4.709e-160	512.0	arCOG01917@1|root,arCOG01917@2157|Archaea,2XYA0@28890|Euryarchaeota	28890|Euryarchaeota	O	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zinc_ribbon_2
LZS1_k127_5369629_21	304371.MCP_2737	2.981e-36	145.0	arCOG05710@1|root,arCOG05710@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5369629_20	552811.Dehly_0860	2.439e-43	163.0	COG1611@1|root,COG1611@2|Bacteria,2G6YH@200795|Chloroflexi,34CSH@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DNA_processg_A
LZS1_k127_5369629_12	1385935.N836_21720	3.789e-78	271.0	COG2006@1|root,COG2006@2|Bacteria,1G0X0@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS1_k127_5369629_5	1236689.MMALV_02920	2.431e-95	318.0	COG1131@1|root,arCOG00196@2157|Archaea,2Y7PZ@28890|Euryarchaeota	28890|Euryarchaeota	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_5369629_4	688269.Theth_0192	2.742e-96	337.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS1_k127_5369629_10	521011.Mpal_0706	1.118e-78	278.0	COG0475@1|root,arCOG01953@2157|Archaea,2XV77@28890|Euryarchaeota,2NATR@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
LZS1_k127_5369629_24	768671.ThimaDRAFT_2989	1.075e-20	96.0	2ED63@1|root,3372T@2|Bacteria,1NEJK@1224|Proteobacteria,1SD1X@1236|Gammaproteobacteria,1WZG9@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5369629_29	742823.HMPREF9465_01913	4.506e-05	51.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,4PR8T@995019|Sutterellaceae	28216|Betaproteobacteria	S	FR47-like protein	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
LZS1_k127_5381469_4	429009.Adeg_1087	6.98e-32	127.0	COG1433@1|root,COG1433@2|Bacteria,1VFDZ@1239|Firmicutes,24R8N@186801|Clostridia,42GPN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
LZS1_k127_5381469_11	338963.Pcar_1581	5.09e-06	53.0	COG1433@1|root,COG1433@2|Bacteria,1N7IQ@1224|Proteobacteria,42WGA@68525|delta/epsilon subdivisions,2WS2U@28221|Deltaproteobacteria,43VG7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
LZS1_k127_5381469_9	693661.Arcve_0452	3.103e-08	64.0	COG1342@1|root,arCOG02238@2157|Archaea,2Y6EW@28890|Euryarchaeota,247FZ@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function  DUF134	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
LZS1_k127_5381469_1	387631.Asulf_02203	5.32e-92	311.0	COG0489@1|root,arCOG00585@2157|Archaea,2XTU2@28890|Euryarchaeota	28890|Euryarchaeota	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
LZS1_k127_5381469_8	941449.dsx2_2965	4.836e-16	85.0	COG2044@1|root,COG2044@2|Bacteria,1RIFN@1224|Proteobacteria,42UMB@68525|delta/epsilon subdivisions,2WQMD@28221|Deltaproteobacteria,2MD9S@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM DsrE family protein	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
LZS1_k127_5381469_2	243232.MJ_0455	2.962e-59	211.0	COG4887@1|root,arCOG05003@2157|Archaea,2XX1U@28890|Euryarchaeota,23R39@183939|Methanococci	183939|Methanococci	S	Protein of unknown function (DUF1847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1847
LZS1_k127_5381469_7	589924.Ferp_0134	3.175e-19	95.0	COG3413@1|root,arCOG02271@2157|Archaea,2XU8X@28890|Euryarchaeota	28890|Euryarchaeota	K	Bacterio-opsin activator HTH domain-containing protein	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,HTH_10
LZS1_k127_5381469_6	370438.PTH_0588	8.151e-21	95.0	COG1342@1|root,COG1342@2|Bacteria,1V5RE@1239|Firmicutes,25CFP@186801|Clostridia,262AN@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
LZS1_k127_5381469_5	387631.Asulf_00347	1.043e-24	113.0	COG1718@1|root,arCOG01180@2157|Archaea,2XU2H@28890|Euryarchaeota,245RP@183980|Archaeoglobi	183980|Archaeoglobi	T	Serine threonine protein kinase involved in cell cycle control	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
LZS1_k127_5381469_3	224325.AF_2030	1.326e-32	144.0	COG1014@1|root,arCOG01602@2157|Archaea,2XXK2@28890|Euryarchaeota,24729@183980|Archaeoglobi	183980|Archaeoglobi	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
LZS1_k127_5381469_0	673860.AciM339_0762	2.244e-188	606.0	COG4231@1|root,arCOG01609@2157|Archaea,2XUNR@28890|Euryarchaeota,3F2HQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,Fer4_7,POR_N,TPP_enzyme_C
LZS1_k127_5381469_12	1449063.JMLS01000005_gene3324	0.0001351	54.0	COG2374@1|root,COG4085@1|root,COG5492@1|root,COG2374@2|Bacteria,COG4085@2|Bacteria,COG5492@2|Bacteria,1TSI3@1239|Firmicutes,4HAWG@91061|Bacilli,26QIC@186822|Paenibacillaceae	91061|Bacilli	E	lipolytic protein G-D-S-L family	yhcR	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,ChitinaseA_N
LZS1_k127_5381469_10	529709.PYCH_05560	1.146e-06	61.0	COG1572@1|root,arCOG07086@2157|Archaea,2Y2HS@28890|Euryarchaeota,2436N@183968|Thermococci	183968|Thermococci	G	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
LZS1_k127_5420101_0	1304874.JAFY01000002_gene134	3.079e-75	265.0	COG1173@1|root,COG1173@2|Bacteria,3T9XU@508458|Synergistetes	508458|Synergistetes	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_5420101_2	479435.Kfla_1612	9.235e-18	100.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4DPH8@85009|Propionibacteriales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_5420101_1	991905.SL003B_3564	3.641e-51	210.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria,4BRG6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
LZS1_k127_5452039_2	374847.Kcr_1093	4.657e-91	329.0	COG0747@1|root,arCOG01534@2157|Archaea	2157|Archaea	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_5452039_3	1117647.M5M_13700	2.049e-10	74.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1J590@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	bprV	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,PPC,Peptidase_S8
LZS1_k127_5452039_0	1094980.Mpsy_2748	8.51e-157	525.0	COG0513@1|root,arCOG00558@2157|Archaea,2XUS4@28890|Euryarchaeota,2N99K@224756|Methanomicrobia	224756|Methanomicrobia	L	DEAD DEAH box helicase domain protein	-	-	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
LZS1_k127_5452039_1	521045.Kole_0200	4.432e-143	460.0	COG0004@1|root,COG0004@2|Bacteria,2GD3C@200918|Thermotogae	200918|Thermotogae	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS1_k127_5471095_0	1380763.BG53_03300	1.229e-152	497.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,26TDB@186822|Paenibacillaceae	91061|Bacilli	I	catalyzes the conversion of acetate and CoA to acetyl-CoA	acsA_1	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS1_k127_5471095_1	589865.DaAHT2_0828	6.777e-115	377.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,2MHRX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
LZS1_k127_5471095_2	697281.Mahau_0889	7.304e-74	253.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,42FHK@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM formate-tetrahydrofolate ligase FTHFS	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
LZS1_k127_5505197_2	649747.HMPREF0083_00885	6.501e-75	261.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli,26U7E@186822|Paenibacillaceae	91061|Bacilli	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS1_k127_5505197_1	269799.Gmet_2704	6.06e-104	348.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,43U4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
LZS1_k127_5505197_4	574087.Acear_0866	1.161e-51	191.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,3WANJ@53433|Halanaerobiales	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
LZS1_k127_5505197_0	517418.Ctha_1536	1.606e-164	530.0	COG0446@1|root,COG0446@2|Bacteria,1FDD4@1090|Chlorobi	1090|Chlorobi	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS1_k127_5505197_3	309801.trd_1977	2.431e-67	239.0	COG0475@1|root,COG0475@2|Bacteria,2G9JV@200795|Chloroflexi,27YQT@189775|Thermomicrobia	189775|Thermomicrobia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
LZS1_k127_5508480_0	1236689.MMALV_16940	1.514e-140	455.0	COG0183@1|root,arCOG01282@2157|Archaea,2XT8C@28890|Euryarchaeota	28890|Euryarchaeota	I	Acetyl-CoA acetyltransferase	yqeF	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS1_k127_5508480_1	673860.AciM339_0076	7.562e-121	403.0	COG1571@1|root,arCOG01115@2157|Archaea,2XTGD@28890|Euryarchaeota,3F2IS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA	tiaS	GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	6.3.4.22	ko:K06932	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1743,tRNA_anti-codon
LZS1_k127_5508480_4	273116.14324632	3.86e-05	51.0	arCOG05351@1|root,arCOG05351@2157|Archaea,2Y1XZ@28890|Euryarchaeota,242GE@183967|Thermoplasmata	183967|Thermoplasmata	S	Protein of unknown function (DUF3198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3198
LZS1_k127_5508480_3	342949.PNA2_1759	2.604e-66	243.0	COG2262@1|root,arCOG00353@2157|Archaea,2XT2W@28890|Euryarchaeota,2431W@183968|Thermococci	183968|Thermococci	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS1_k127_5508480_2	439481.Aboo_0001	4.998e-86	289.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,3F2IJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in regulation of DNA replication	cdc6	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA,AAA_16,AAA_22,Cdc6_C
LZS1_k127_5511604_2	673860.AciM339_0054	7.825e-05	53.0	arCOG05803@1|root,arCOG05803@2157|Archaea,2Y76B@28890|Euryarchaeota,3F3GQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5511604_0	635013.TherJR_0633	2.487e-74	263.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,261M9@186807|Peptococcaceae	186801|Clostridia	C	PFAM Iron-containing alcohol dehydrogenase	dhaD	-	1.1.1.6	ko:K00005,ko:K08317	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
LZS1_k127_5511604_1	582515.KR51_00019980	7.475e-05	49.0	COG0500@1|root,COG2226@2|Bacteria,1G7DS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
LZS1_k127_5549848_0	247490.KSU1_C0515	1.141e-144	466.0	COG1063@1|root,COG1063@2|Bacteria,2J2DX@203682|Planctomycetes	203682|Planctomycetes	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS1_k127_5549848_1	1131266.ARWQ01000002_gene677	3.832e-119	388.0	COG1830@1|root,arCOG04044@2157|Archaea,41S64@651137|Thaumarchaeota	651137|Thaumarchaeota	E	DeoC/LacD family aldolase	-	-	2.3.1.245	ko:K08321	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DeoC
LZS1_k127_5549848_2	877455.Metbo_2111	2.777e-49	179.0	COG1027@1|root,arCOG01750@2157|Archaea,2Y84P@28890|Euryarchaeota	28890|Euryarchaeota	E	Fumarase C C-terminus	-	-	4.2.1.2,4.3.1.1	ko:K01679,ko:K01744	ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R00490,R01082	RC00316,RC00443,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS1_k127_5561848_5	1396141.BATP01000056_gene3278	8.265e-07	59.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
LZS1_k127_5561848_4	439481.Aboo_0010	4.231e-07	62.0	COG1361@1|root,COG1572@1|root,arCOG01917@1|root,arCOG01917@2157|Archaea,arCOG02079@2157|Archaea,arCOG02532@2157|Archaea,2Y1TH@28890|Euryarchaeota,3F2UJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DZR,zinc_ribbon_2
LZS1_k127_5561848_3	877415.JNJQ01000020_gene1549	1.114e-16	89.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,3VR1Q@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Protein of unknown function DUF111	-	-	-	-	-	-	-	-	-	-	-	-	DUF111
LZS1_k127_5561848_2	1047013.AQSP01000144_gene918	1.331e-22	99.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.14,2.8.1.7	ko:K00549,ko:K04085,ko:K04487,ko:K08363	ko00270,ko00450,ko00730,ko01100,ko01110,ko01230,ko04122,map00270,map00450,map00730,map01100,map01110,map01230,map04122	M00017	R04405,R07460,R09365,R11528,R11529	RC00035,RC00113,RC01241,RC01789,RC02313	ko00000,ko00001,ko00002,ko01000,ko02000,ko02048,ko03016,ko03029	1.A.72.1	-	-	DUF2249,Rhodanese,TusA
LZS1_k127_5561848_1	521011.Mpal_1671	1.099e-38	148.0	COG2044@1|root,arCOG02066@2157|Archaea,2XWA5@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM DsrE family protein	-	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,TusA
LZS1_k127_5561848_0	1382359.JIAL01000001_gene821	9.629e-67	233.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria,2JI55@204432|Acidobacteriia	204432|Acidobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS1_k127_5565050_0	342949.PNA2_0095	2.771e-92	321.0	COG0446@1|root,arCOG01069@2157|Archaea,2XT0A@28890|Euryarchaeota,24368@183968|Thermococci	183968|Thermococci	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.6.3.3	ko:K17870	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS1_k127_5565050_3	439481.Aboo_0862	2.06e-77	265.0	COG0081@1|root,arCOG04289@2157|Archaea,2XTJF@28890|Euryarchaeota,3F2IX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds directly to 23S rRNA. Probably involved in E site tRNA release	rpl1	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
LZS1_k127_5565050_1	673860.AciM339_0147	6.585e-87	298.0	COG0244@1|root,arCOG04288@2157|Archaea,2XU7C@28890|Euryarchaeota,3F2JW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl10	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s,Ribosomal_L10
LZS1_k127_5565050_4	673860.AciM339_0148	1.643e-25	109.0	COG2058@1|root,arCOG04287@2157|Archaea,2XYQ9@28890|Euryarchaeota,3F2TF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rpl12	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02869	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_60s
LZS1_k127_5565050_6	439481.Aboo_0838	1.707e-13	76.0	arCOG05345@1|root,arCOG05345@2157|Archaea,2Y117@28890|Euryarchaeota,3F3G9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5565050_2	1236689.MMALV_10400	1.097e-83	291.0	COG1474@1|root,arCOG00467@2157|Archaea,2XU73@28890|Euryarchaeota,3F2IJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Involved in regulation of DNA replication	-	-	-	ko:K10725	-	-	-	-	ko00000,ko03032	-	-	-	AAA_22
LZS1_k127_5565050_5	1094980.Mpsy_2611	3.177e-21	100.0	COG0745@1|root,arCOG02348@1|root,arCOG03799@1|root,arCOG02348@2157|Archaea,arCOG02592@2157|Archaea,arCOG03799@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF835)	-	-	2.7.7.65,6.3.4.2	ko:K01937,ko:K02488	ko00240,ko01100,ko02020,ko04112,map00240,map01100,map02020,map04112	M00052,M00511	R00571,R00573,R08057	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	DUF835,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_5565572_14	1236689.MMALV_16940	8.381e-22	95.0	COG0183@1|root,arCOG01282@2157|Archaea,2XT8C@28890|Euryarchaeota	28890|Euryarchaeota	I	Acetyl-CoA acetyltransferase	yqeF	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS1_k127_5565572_1	693661.Arcve_1145	3.012e-109	370.0	COG0624@1|root,arCOG01107@2157|Archaea,2XU86@28890|Euryarchaeota,245SX@183980|Archaeoglobi	183980|Archaeoglobi	E	acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS1_k127_5565572_3	1236689.MMALV_16910	1.654e-102	342.0	COG0552@1|root,arCOG01227@2157|Archaea,2XUBI@28890|Euryarchaeota,3F2GR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
LZS1_k127_5565572_15	1054217.TALC_01571	6.749e-13	75.0	COG1730@1|root,arCOG01341@2157|Archaea	2157|Archaea	O	Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding	pfdA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K04797	-	-	-	-	ko00000,ko03110	-	-	-	Prefoldin
LZS1_k127_5565572_18	192952.MM_0808	0.0006493	49.0	COG2157@1|root,arCOG04175@2157|Archaea,2Y6W8@28890|Euryarchaeota,2NA5B@224756|Methanomicrobia	224756|Methanomicrobia	J	Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A	rplX	-	-	ko:K02944	ko03010,map03010	M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18A
LZS1_k127_5565572_10	592015.HMPREF1705_00649	3.056e-62	224.0	COG1856@1|root,COG1856@2|Bacteria,3TB4N@508458|Synergistetes	508458|Synergistetes	S	Radical SAM domain protein	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
LZS1_k127_5565572_6	673860.AciM339_1321	7.498e-85	295.0	COG1467@1|root,arCOG04110@2157|Archaea,2XUZF@28890|Euryarchaeota,3F2IZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priS	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02683	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_S
LZS1_k127_5565572_17	273116.14324495	3.734e-05	55.0	arCOG05238@1|root,arCOG05238@2157|Archaea,2Y0YG@28890|Euryarchaeota,242C6@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5565572_9	1042877.GQS_03410	6.222e-67	238.0	COG1122@1|root,arCOG00202@2157|Archaea,2Y7MJ@28890|Euryarchaeota,243GS@183968|Thermococci	183968|Thermococci	P	ATP-binding protein	-	-	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
LZS1_k127_5565572_8	479434.Sthe_3089	6.107e-70	248.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,27YU5@189775|Thermomicrobia	189775|Thermomicrobia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
LZS1_k127_5565572_12	1343739.PAP_00865	3.819e-43	167.0	COG0619@1|root,arCOG02250@2157|Archaea,2Y0D5@28890|Euryarchaeota,2436Y@183968|Thermococci	183968|Thermococci	P	ABC-type cobalt transport system, permease	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
LZS1_k127_5565572_13	368408.Tpen_1668	1.138e-28	124.0	COG4720@1|root,arCOG05752@2157|Archaea,2XQ9C@28889|Crenarchaeota	28889|Crenarchaeota	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
LZS1_k127_5565572_2	1054217.TALC_00487	1.48e-108	370.0	COG0277@1|root,arCOG00340@2157|Archaea,2XVP5@28890|Euryarchaeota	28890|Euryarchaeota	C	FAD binding domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
LZS1_k127_5565572_5	673860.AciM339_0113	3.549e-92	321.0	COG0281@1|root,arCOG01331@2157|Archaea,2XTRZ@28890|Euryarchaeota,3F36G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
LZS1_k127_5565572_0	439481.Aboo_0457	1.884e-155	504.0	COG0269@1|root,arCOG00053@2157|Archaea,2XV47@28890|Euryarchaeota,3F2IP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Aldolase/RraA	-	-	4.1.2.43,5.3.1.27	ko:K13831	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338,R05339,R09780	RC00377,RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,RraA-like
LZS1_k127_5565572_4	439481.Aboo_0716	7.85e-95	323.0	COG0467@1|root,arCOG01171@2157|Archaea,2XTU3@28890|Euryarchaeota,3F31P@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Rad51	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_5565572_11	673860.AciM339_0350	6.363e-46	177.0	arCOG02452@1|root,arCOG02452@2157|Archaea,2Y71S@28890|Euryarchaeota,3F36K@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	COG0467 RecA-superfamily ATPases implicated in signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5565572_7	439481.Aboo_0714	1.078e-70	247.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y69G@28890|Euryarchaeota,3F39I@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_5565572_16	485914.Hmuk_2866	3.588e-05	48.0	arCOG02416@1|root,arCOG02416@2157|Archaea,2Y01H@28890|Euryarchaeota,23XTV@183963|Halobacteria	183963|Halobacteria	N	protein conserved in archaea	pilA2	-	-	-	-	-	-	-	-	-	-	-	Pilin_N
LZS1_k127_557547_8	344747.PM8797T_02424	1.805e-08	66.0	COG1404@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG4932@1|root,COG5276@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.4,3.4.21.62,3.4.24.40	ko:K01179,ko:K01342,ko:K01406,ko:K07004,ko:K12287,ko:K14194,ko:K15125,ko:K20276	ko00500,ko01100,ko01503,ko02024,ko05133,ko05150,map00500,map01100,map01503,map02024,map05133,map05150	-	R06200,R11307,R11308	-	ko00000,ko00001,ko00536,ko01000,ko01002,ko02044,ko03110	-	GH5,GH9	-	Calx-beta,Exo_endo_phos,HemolysinCabind,VCBS
LZS1_k127_557547_3	1304874.JAFY01000002_gene135	2.996e-71	252.0	COG0601@1|root,COG0601@2|Bacteria,3TAG1@508458|Synergistetes	508458|Synergistetes	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_557547_2	1122609.AUGT01000009_gene3345	9.632e-75	261.0	COG1173@1|root,COG1173@2|Bacteria,2GKAW@201174|Actinobacteria,4DPB4@85009|Propionibacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS1_k127_557547_4	1236689.MMALV_13650	1.808e-65	233.0	COG1890@1|root,arCOG04186@2157|Archaea,2XSX9@28890|Euryarchaeota,3F2MY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eS1 family	rps3ae	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576	-	ko:K02984	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S3Ae
LZS1_k127_557547_1	1236689.MMALV_13630	1.75e-112	377.0	COG0003@1|root,arCOG02849@2157|Archaea,2XT6V@28890|Euryarchaeota	28890|Euryarchaeota	D	Arsenite-activated ATPase ArsA	arsA1	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
LZS1_k127_557547_5	370438.PTH_0486	2.661e-35	139.0	COG1142@1|root,COG1142@2|Bacteria,1UHYS@1239|Firmicutes,24JZC@186801|Clostridia,263U8@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_9
LZS1_k127_557547_0	1150474.JQJI01000035_gene950	8.428e-184	593.0	COG2414@1|root,COG2414@2|Bacteria,2GCI5@200918|Thermotogae	200918|Thermotogae	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
LZS1_k127_557547_7	693661.Arcve_1632	5.57e-17	89.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
LZS1_k127_557547_6	439481.Aboo_0215	4.561e-18	87.0	COG1719@1|root,arCOG01688@2157|Archaea	2157|Archaea	K	PFAM 4-vinyl reductase, 4VR	-	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	DUF2507,V4R
LZS1_k127_5595258_2	273075.Ta0520	2.318e-21	98.0	COG1836@1|root,arCOG02245@2157|Archaea,2XTBR@28890|Euryarchaeota,241UU@183967|Thermoplasmata	183967|Thermoplasmata	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
LZS1_k127_5595258_1	1246995.AFR_00785	4.601e-37	155.0	COG2227@1|root,COG2227@2|Bacteria,2IDU6@201174|Actinobacteria,4DBNN@85008|Micromonosporales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS1_k127_5595258_0	351160.RCIX924	3.806e-37	150.0	COG1011@1|root,arCOG02291@2157|Archaea	2157|Archaea	S	hydrolase (HAD superfamily)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS1_k127_5625073_3	1236689.MMALV_01820	1.478e-11	64.0	COG0176@1|root,arCOG05061@2157|Archaea,2XTET@28890|Euryarchaeota,3F2MD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Transaldolase/Fructose-6-phosphate aldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
LZS1_k127_5625073_1	1449126.JQKL01000003_gene1756	5.092e-111	380.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,268B4@186813|unclassified Clostridiales	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS1_k127_5625073_0	370438.PTH_2750	3.06e-115	377.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
LZS1_k127_5625073_2	1209989.TepiRe1_1178	3.8e-66	231.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,42GE6@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
LZS1_k127_5654746_2	330214.NIDE2777	2.942e-31	126.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	yddE	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
LZS1_k127_5654746_3	767029.HMPREF9154_0947	4.963e-10	67.0	COG3428@1|root,COG3428@2|Bacteria,2GK6Y@201174|Actinobacteria,4DRJ7@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
LZS1_k127_5654746_4	797302.Halru_0151	4.271e-09	71.0	COG1361@1|root,arCOG02499@1|root,arCOG02545@1|root,arCOG06512@1|root,arCOG07560@1|root,arCOG02080@2157|Archaea,arCOG02499@2157|Archaea,arCOG02545@2157|Archaea,arCOG06512@2157|Archaea,arCOG07560@2157|Archaea	2157|Archaea	Q	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,NosD
LZS1_k127_5654746_0	1457250.BBMO01000001_gene1581	5.667e-53	215.0	COG3291@1|root,arCOG02526@1|root,arCOG03499@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,arCOG03499@2157|Archaea,2XUY6@28890|Euryarchaeota	28890|Euryarchaeota	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD,Pilin_N,SdrD_B
LZS1_k127_5654746_1	351160.RCIX1775	1.917e-49	181.0	COG1122@1|root,arCOG00202@2157|Archaea,2XW7F@28890|Euryarchaeota	28890|Euryarchaeota	E	COG1122 ABC-type cobalt transport system, ATPase component	nikO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
LZS1_k127_5663810_6	673860.AciM339_1374	1.688e-36	156.0	arCOG08157@1|root,arCOG08157@2157|Archaea,2Y70I@28890|Euryarchaeota,3F332@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5663810_9	387631.Asulf_00955	8.058e-23	106.0	arCOG07100@1|root,arCOG07100@2157|Archaea,2XZZK@28890|Euryarchaeota,2470E@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
LZS1_k127_5663810_4	591019.Shell_0171	6.858e-42	169.0	COG0675@1|root,arCOG00679@2157|Archaea,2XRMB@28889|Crenarchaeota	28889|Crenarchaeota	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
LZS1_k127_5663810_8	945713.IALB_1477	3.122e-25	125.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
LZS1_k127_5663810_7	935839.JAGJ01000013_gene2870	4.597e-34	154.0	COG3291@1|root,COG3386@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,2GNGF@201174|Actinobacteria,4F43T@85017|Promicromonosporaceae	201174|Actinobacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF1080
LZS1_k127_5663810_13	246437.XP_006172166.1	0.0009642	46.0	KOG1388@1|root,KOG1388@2759|Eukaryota,38DSY@33154|Opisthokonta,3BCFB@33208|Metazoa,3E45S@33213|Bilateria	33208|Metazoa	TV	EGF-like domain	atrnl1	GO:0007275,GO:0007399,GO:0008037,GO:0008038,GO:0008039,GO:0008150,GO:0009987,GO:0022008,GO:0030154,GO:0030182,GO:0032501,GO:0032502,GO:0048468,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869	-	-	-	-	-	-	-	-	-	-	CUB,EGF_2,Kelch_1,Kelch_3,Kelch_4,Kelch_5,Laminin_EGF,Lectin_C,PSI
LZS1_k127_5663810_10	59374.Fisuc_0063	1.102e-19	106.0	COG2911@1|root,COG4254@1|root,COG2911@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	lgt	-	-	ko:K09800,ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001,ko02000	-	-	-	FecR
LZS1_k127_5663810_12	1463857.JOFZ01000015_gene764	3.737e-07	65.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,TGFb_propeptide,Tox-REase-5
LZS1_k127_5663810_1	935948.KE386495_gene2050	4.431e-59	210.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,24DYE@186801|Clostridia,42FWT@68295|Thermoanaerobacterales	186801|Clostridia	C	Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS1_k127_5663810_11	536232.CLM_0536	1.158e-15	89.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,36DTA@31979|Clostridiaceae	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS1_k127_5663810_2	595460.RRSWK_00889	1.806e-45	188.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,2IXFD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
LZS1_k127_5663810_0	1304874.JAFY01000002_gene577	1.025e-85	302.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_5663810_5	192952.MM_2047	1.618e-41	163.0	COG5012@1|root,arCOG02028@2157|Archaea,2XX6R@28890|Euryarchaeota,2NA0S@224756|Methanomicrobia	224756|Methanomicrobia	S	Acts probably as a methyl group carrier between MttB and either MtbA or MtaA	-	-	-	ko:K14084	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124	RC00035,RC00732,RC02984	ko00000,ko00001,ko00002	-	-	iAF692.Mbar_A1503	B12-binding,B12-binding_2
LZS1_k127_5663810_3	138119.DSY4970	4.707e-44	172.0	COG5598@1|root,COG5598@2|Bacteria,1V0ZE@1239|Firmicutes,24D6Y@186801|Clostridia,266YG@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
LZS1_k127_5664529_5	457570.Nther_2418	1.592e-23	103.0	COG1149@1|root,COG1149@2|Bacteria,1TP7Y@1239|Firmicutes,249ER@186801|Clostridia	186801|Clostridia	C	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
LZS1_k127_5664529_3	706587.Desti_1973	5.012e-86	295.0	COG1149@1|root,COG1149@2|Bacteria,1MVPB@1224|Proteobacteria,42MJ5@68525|delta/epsilon subdivisions,2WJ9M@28221|Deltaproteobacteria,2MQXE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
LZS1_k127_5664529_4	386456.JQKN01000005_gene434	2.769e-50	186.0	COG1321@1|root,arCOG02099@2157|Archaea,2XSWC@28890|Euryarchaeota,23P0S@183925|Methanobacteria	183925|Methanobacteria	K	Iron dependent	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
LZS1_k127_5664529_0	192952.MM_1033	3.368e-123	417.0	COG0370@1|root,arCOG00359@2157|Archaea,2XU46@28890|Euryarchaeota,2N913@224756|Methanomicrobia	224756|Methanomicrobia	P	Ferrous iron transport B domain protein	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
LZS1_k127_5664529_2	439481.Aboo_0589	1.562e-106	359.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F38N@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS1_k127_5664529_1	1459636.NTE_03463	1.459e-119	396.0	COG1055@1|root,arCOG00238@2157|Archaea	2157|Archaea	P	Citrate transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	CitMHS,Na_sulph_symp
LZS1_k127_5672218_3	56780.SYN_00387	1.087e-75	261.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42Q5K@68525|delta/epsilon subdivisions,2X5HI@28221|Deltaproteobacteria,2MRD9@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS1_k127_5672218_5	368407.Memar_1039	1.003e-53	201.0	COG1392@1|root,arCOG02640@2157|Archaea	2157|Archaea	P	Phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
LZS1_k127_5672218_0	439481.Aboo_1538	2.911e-141	464.0	COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,3F2G6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pmm4	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2225	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS1_k127_5672218_4	1236689.MMALV_02260	4.67e-70	252.0	COG0010@1|root,arCOG01700@2157|Archaea,2XTEP@28890|Euryarchaeota,3F2M6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
LZS1_k127_5672218_6	439481.Aboo_0003	1.075e-49	180.0	COG0231@1|root,arCOG04277@2157|Archaea,2XX3E@28890|Euryarchaeota,3F2PU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Functions by promoting the formation of the first peptide bond	eif5a	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03263	-	-	-	-	ko00000,ko03012	-	-	-	EFP_N,eIF-5a
LZS1_k127_5672218_2	1236689.MMALV_02290	1.134e-84	293.0	COG1498@1|root,arCOG01923@2157|Archaea,2XUEA@28890|Euryarchaeota,3F2QB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	snoRNA binding domain, fibrillarin	nop5	GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K14564	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009	-	-	-	Nop
LZS1_k127_5672218_1	439481.Aboo_1543	3.265e-125	410.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
LZS1_k127_5680129_3	339860.Msp_1230	9.87e-06	48.0	COG0375@1|root,arCOG04426@2157|Archaea,2XZI2@28890|Euryarchaeota,23P60@183925|Methanobacteria	183925|Methanobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
LZS1_k127_5680129_2	1054217.TALC_01355	2.299e-19	94.0	COG0298@1|root,arCOG04427@2157|Archaea,2Y0AJ@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
LZS1_k127_5680129_0	1054217.TALC_00534	1.75e-189	615.0	COG0068@1|root,arCOG01187@2157|Archaea,2XTHZ@28890|Euryarchaeota	28890|Euryarchaeota	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Peptidase_M22,Sua5_yciO_yrdC,zf-HYPF
LZS1_k127_5680129_1	323259.Mhun_2484	3.071e-75	258.0	COG0378@1|root,arCOG01231@2157|Archaea,2XUJS@28890|Euryarchaeota,2N9SQ@224756|Methanomicrobia	224756|Methanomicrobia	O	TIGRFAM hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
LZS1_k127_5700652_1	926569.ANT_19690	1.525e-28	123.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS1_k127_5700652_0	1094980.Mpsy_3151	2.275e-281	937.0	COG5520@1|root,arCOG03769@1|root,arCOG07561@1|root,arCOG03769@2157|Archaea,arCOG07561@2157|Archaea,arCOG09138@2157|Archaea,2XV3J@28890|Euryarchaeota,2NBAU@224756|Methanomicrobia	224756|Methanomicrobia	K	glycoside hydrolase, family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5711523_0	1054217.TALC_01148	1.196e-24	108.0	COG0585@1|root,arCOG04252@2157|Archaea,2XUTK@28890|Euryarchaeota,241NZ@183967|Thermoplasmata	183967|Thermoplasmata	J	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
LZS1_k127_5711523_2	439481.Aboo_1383	4.805e-14	81.0	COG1761@1|root,arCOG04111@2157|Archaea,2XZVZ@28890|Euryarchaeota,3F2UR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoL	-	2.7.7.6	ko:K03056	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_L_2
LZS1_k127_5711523_1	1343739.PAP_06530	1.931e-15	86.0	COG1111@1|root,arCOG00872@2157|Archaea,2XTBV@28890|Euryarchaeota,243CX@183968|Thermococci	183968|Thermococci	L	ERCC4 domain	-	-	-	ko:K10896	ko03460,map03460	M00413	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	DEAD,ERCC4,HHH_2,Helicase_C
LZS1_k127_5734949_0	589865.DaAHT2_0828	1.462e-91	306.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,2MHRX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
LZS1_k127_5734949_1	997346.HMPREF9374_1802	4.664e-47	179.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,27B6R@186824|Thermoactinomycetaceae	91061|Bacilli	I	AMP-binding enzyme C-terminal domain	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS1_k127_5758428_1	1448860.BBJO01000014_gene1239	4.7e-09	68.0	COG0247@1|root,arCOG00332@2157|Archaea,2XTPG@28890|Euryarchaeota,23SEN@183963|Halobacteria	183963|Halobacteria	C	COG0247 Fe-S oxidoreductase	hdrD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4,Fer4_10,Fer4_8,Fer4_9,Nitrate_red_gam
LZS1_k127_5758428_0	1265505.ATUG01000002_gene1138	3.391e-49	190.0	COG0311@1|root,COG0311@2|Bacteria	2|Bacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
LZS1_k127_576506_1	1054217.TALC_00034	1.914e-42	157.0	COG0519@1|root,arCOG00085@2157|Archaea,2XT82@28890|Euryarchaeota,241KI@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the synthesis of GMP from XMP	guaAB	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GMP_synt_C,NAD_synthase
LZS1_k127_576506_0	439481.Aboo_0606	1.533e-69	240.0	COG0518@1|root,arCOG00087@2157|Archaea,2XT3G@28890|Euryarchaeota,3F2M8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the synthesis of GMP from XMP	guaAA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
LZS1_k127_576506_3	439481.Aboo_0587	1.779e-07	59.0	COG2034@1|root,arCOG02717@2157|Archaea,2XZVB@28890|Euryarchaeota,3F3HD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function DUF131	-	-	-	-	-	-	-	-	-	-	-	-	DUF131
LZS1_k127_576506_2	439481.Aboo_0014	1.298e-29	129.0	arCOG02780@1|root,arCOG02780@2157|Archaea,2Y714@28890|Euryarchaeota,3F34G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5781051_0	439481.Aboo_1381	5.212e-247	803.0	COG1196@1|root,arCOG00371@2157|Archaea,2XSVK@28890|Euryarchaeota,3F2HY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
LZS1_k127_5781051_1	439481.Aboo_1382	1.681e-38	162.0	COG1354@1|root,arCOG02610@2157|Archaea,2XZHK@28890|Euryarchaeota,3F2QG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	chromosome segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
LZS1_k127_5788861_0	338963.Pcar_0639	5.248e-76	269.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,43SPT@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS1_k127_5788861_1	338963.Pcar_0640	3.308e-15	79.0	29AVF@1|root,2ZXUP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5788861_2	1105367.CG50_05950	7.328e-07	61.0	COG0454@1|root,COG0454@2|Bacteria,1QU4I@1224|Proteobacteria,2TU4A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
LZS1_k127_5788861_3	272952.HpaP812661	0.0004308	46.0	COG0456@1|root,KOG3139@2759|Eukaryota,3Q8IU@4776|Peronosporales	4776|Peronosporales	S	Acetyltransferase (GNAT) domain	-	-	2.3.1.256	ko:K00670	-	-	-	-	ko00000,ko01000,ko04131	-	-	-	Acetyltransf_1
LZS1_k127_5864547_3	529709.PYCH_13930	3.059e-17	83.0	COG0149@1|root,arCOG01087@2157|Archaea,2XTY3@28890|Euryarchaeota,24332@183968|Thermococci	183968|Thermococci	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM,ThiG
LZS1_k127_5864547_0	1236689.MMALV_09940	9.289e-147	473.0	COG1980@1|root,arCOG04180@2157|Archaea,2XTI0@28890|Euryarchaeota,3F2H5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P)	fbp	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
LZS1_k127_5864547_2	243231.GSU3138	4.04e-44	183.0	COG0642@1|root,COG2197@1|root,COG2197@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42RWK@68525|delta/epsilon subdivisions,2WNCS@28221|Deltaproteobacteria,43SHW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
LZS1_k127_5864547_1	351160.RCIX1774	1.748e-91	310.0	COG1042@1|root,arCOG01340@2157|Archaea,2XT9G@28890|Euryarchaeota,2NAP4@224756|Methanomicrobia	224756|Methanomicrobia	C	CoA binding domain	acdA	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
LZS1_k127_5922294_6	673860.AciM339_0753	9.667e-52	194.0	COG1287@1|root,arCOG02044@2157|Archaea,arCOG05365@2157|Archaea,2Y7QJ@28890|Euryarchaeota,3F2NE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Carboxypeptidase regulatory-like domain	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	CarboxypepD_reg,PMT_2,STT3
LZS1_k127_5922294_4	1054217.TALC_01515	3.863e-70	260.0	COG0284@1|root,arCOG00081@2157|Archaea,2XU66@28890|Euryarchaeota,241PX@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
LZS1_k127_5922294_3	1236689.MMALV_16390	3.681e-109	364.0	COG2108@1|root,arCOG00932@2157|Archaea,2XU78@28890|Euryarchaeota,3F2FA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	4Fe-4S single cluster domain	-	-	-	ko:K07129	-	-	-	-	ko00000	-	-	-	Fer4_14,Radical_SAM
LZS1_k127_5922294_5	1236689.MMALV_16400	9.496e-56	203.0	COG0195@1|root,arCOG01760@2157|Archaea,2Y6CH@28890|Euryarchaeota,3F2TQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Participates in transcription termination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5
LZS1_k127_5922294_8	1236689.MMALV_16410	2.687e-17	93.0	COG1911@1|root,arCOG01752@2157|Archaea,2Y0CU@28890|Euryarchaeota,3F2SJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	PFAM ribosomal protein L7Ae L30e S12e Gadd45	rpl30e	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02908	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L7Ae
LZS1_k127_5922294_2	1236689.MMALV_16420	1.596e-126	420.0	COG0086@1|root,arCOG04256@2157|Archaea,2XTJ6@28890|Euryarchaeota,3F2IB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03042	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Intein_splicing,LAGLIDADG_3,RNA_pol_Rpb1_5
LZS1_k127_5922294_1	1236689.MMALV_16430	0.0	1298.0	COG0086@1|root,arCOG04257@2157|Archaea,2XTBZ@28890|Euryarchaeota,3F2IK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03041	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
LZS1_k127_5922294_0	1236689.MMALV_16440	0.0	1737.0	COG0085@1|root,arCOG01762@2157|Archaea,2XU1X@28890|Euryarchaeota,3F2FW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB1	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03044,ko:K13798	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_4,RNA_pol_Rpb2_5,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
LZS1_k127_5922294_7	1236689.MMALV_16450	3.101e-22	98.0	COG2012@1|root,arCOG04258@2157|Archaea,2Y6XN@28890|Euryarchaeota,3F2S9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoH	-	2.7.7.6	ko:K03053	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_Rpb5_C
LZS1_k127_5934103_0	1054217.TALC_01359	3.892e-55	202.0	COG1608@1|root,arCOG00860@2157|Archaea,2XSUI@28890|Euryarchaeota,241QT@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS1_k127_5934103_1	673860.AciM339_0020	2.029e-20	92.0	COG1581@1|root,arCOG01753@2157|Archaea,2XZH4@28890|Euryarchaeota,3F3FZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
LZS1_k127_5981146_4	316067.Geob_3529	3.059e-34	143.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,43T29@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
LZS1_k127_5981146_0	697303.Thewi_2302	1.105e-262	845.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
LZS1_k127_5981146_5	204669.Acid345_2057	3.316e-14	75.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,3Y519@57723|Acidobacteria,2JMDU@204432|Acidobacteriia	204432|Acidobacteriia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
LZS1_k127_5981146_1	1150864.MILUP08_40325	4.254e-63	238.0	COG2866@1|root,COG2866@2|Bacteria,2GN49@201174|Actinobacteria,4DAA1@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase M14, carboxypeptidase A	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Peptidase_M14
LZS1_k127_5981146_3	673860.AciM339_0509	2.908e-36	141.0	COG1860@1|root,arCOG04477@2157|Archaea,2XX8X@28890|Euryarchaeota,3F2TM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Uncharacterised protein family (UPF0179)	-	-	-	ko:K09730	-	-	-	-	ko00000	-	-	-	UPF0179
LZS1_k127_5981146_2	192952.MM_0590	4.515e-44	162.0	COG0371@1|root,arCOG00982@2157|Archaea,2XT0F@28890|Euryarchaeota,2N90F@224756|Methanomicrobia	224756|Methanomicrobia	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
LZS1_k127_598320_8	696281.Desru_3282	1.184e-41	158.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia,262I5@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
LZS1_k127_598320_0	1365176.N186_00835	8.448e-122	402.0	COG1363@1|root,arCOG01518@2157|Archaea,2XPWC@28889|Crenarchaeota	28889|Crenarchaeota	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
LZS1_k127_598320_7	1054217.TALC_01127	1.965e-46	175.0	COG0717@1|root,arCOG04048@2157|Archaea,2Y6CE@28890|Euryarchaeota,241VF@183967|Thermoplasmata	183967|Thermoplasmata	F	dUTPase	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
LZS1_k127_598320_1	246969.TAM4_706	3.261e-80	280.0	COG2520@1|root,arCOG00033@2157|Archaea,2XTSI@28890|Euryarchaeota,242WN@183968|Thermococci	183968|Thermococci	J	Met-10+ like-protein	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Met_10
LZS1_k127_598320_5	485916.Dtox_0025	3.165e-69	256.0	arCOG05143@1|root,2Z8AM@2|Bacteria,1TSB3@1239|Firmicutes,24IYX@186801|Clostridia	186801|Clostridia	S	Monomethylamine methyltransferase MtmB	-	-	2.1.1.248	ko:K16176	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09998,R10014	RC00035,RC01144,RC02985	ko00000,ko00001,ko00002,ko01000	-	-	-	MtmB
LZS1_k127_598320_6	927704.SELR_27710	4.071e-51	189.0	COG5012@1|root,COG5012@2|Bacteria,1W73B@1239|Firmicutes,4H823@909932|Negativicutes	909932|Negativicutes	S	B12 binding domain	-	-	-	ko:K14084	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124	RC00035,RC00732,RC02984	ko00000,ko00001,ko00002	-	-	-	B12-binding,B12-binding_2
LZS1_k127_598320_2	673860.AciM339_0455	1.445e-78	270.0	COG1798@1|root,arCOG04161@2157|Archaea,2XV63@28890|Euryarchaeota,3F2J0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis	dphB	GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765	2.1.1.98	ko:K20215	-	-	R04481,R08468,R08469,R10306	RC00003,RC00190,RC01155,RC02136,RC02308	ko00000,ko01000	-	-	iAF692.Mbar_A2900	TP_methylase
LZS1_k127_598320_9	1047013.AQSP01000098_gene2574	3.662e-40	154.0	COG0778@1|root,COG0778@2|Bacteria,2NQ10@2323|unclassified Bacteria	2|Bacteria	C	Putative TM nitroreductase	noxC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
LZS1_k127_598320_10	1041930.Mtc_2073	2.346e-23	111.0	COG0206@1|root,COG1234@1|root,COG1650@1|root,arCOG00501@2157|Archaea,arCOG01616@2157|Archaea,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,2N926@224756|Methanomicrobia	224756|Methanomicrobia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin,tRNA_deacylase
LZS1_k127_598320_3	1265490.JHVY01000009_gene4261	6.803e-77	281.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1GS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0475 Kef-type K transport systems, membrane components	IV02_22945	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
LZS1_k127_598320_4	1379698.RBG1_1C00001G1268	9.41e-75	265.0	COG0420@1|root,COG0420@2|Bacteria,2NQ16@2323|unclassified Bacteria	2|Bacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
LZS1_k127_6027445_1	1041930.Mtc_2045	8.018e-39	166.0	COG2202@1|root,arCOG03931@1|root,arCOG03931@2157|Archaea,arCOG06515@2157|Archaea	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	ko:K06930	-	-	-	-	ko00000	-	-	-	BAT,GAF_2,HATPase_c,HTH_10,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phage_integrase,Response_reg
LZS1_k127_6027445_0	330214.NIDE2777	5.176e-47	177.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	yddE	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
LZS1_k127_6050088_3	1042156.CXIVA_15440	6.681e-29	118.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,36DXW@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_6050088_2	439481.Aboo_0588	5.483e-33	139.0	COG1340@1|root,arCOG01159@2157|Archaea,2Y70M@28890|Euryarchaeota,3F338@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	archaeal coiled-coil protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6050088_0	593117.TGAM_0611	1.766e-42	166.0	COG2820@1|root,arCOG01324@2157|Archaea,2Y06F@28890|Euryarchaeota,244QX@183968|Thermococci	183968|Thermococci	F	Uridine phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
LZS1_k127_6050088_1	1250232.JQNJ01000001_gene2070	1.247e-38	149.0	COG4948@1|root,COG4948@2|Bacteria,4NG8N@976|Bacteroidetes,1HWNA@117743|Flavobacteriia	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	4.2.1.113,5.1.1.20	ko:K02549,ko:K19802	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031,R10938	RC01053,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS1_k127_6091168_3	1120973.AQXL01000117_gene387	6.523e-20	100.0	COG0500@1|root,COG2226@2|Bacteria,1VAEA@1239|Firmicutes,4HIBH@91061|Bacilli	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
LZS1_k127_6091168_0	1121468.AUBR01000023_gene2754	1.295e-111	370.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,24DP8@186801|Clostridia,42GWZ@68295|Thermoanaerobacterales	186801|Clostridia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
LZS1_k127_6091168_2	387631.Asulf_01349	1.083e-24	109.0	arCOG03847@1|root,arCOG03847@2157|Archaea,2XYIE@28890|Euryarchaeota,2475E@183980|Archaeoglobi	183980|Archaeoglobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6091168_1	439481.Aboo_1452	6.401e-34	146.0	arCOG06948@1|root,arCOG06948@2157|Archaea,2XWV7@28890|Euryarchaeota,3F32R@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_4
LZS1_k127_6140157_6	673860.AciM339_0926	1.01e-61	218.0	COG1782@1|root,arCOG00543@2157|Archaea,2XTIM@28890|Euryarchaeota,3F2GJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	KH domain	epf2	-	-	ko:K07041	-	-	-	-	ko00000	-	-	-	Beta-Casp,KH_2,KH_7,Lactamase_B,Lactamase_B_6,RMMBL
LZS1_k127_6140157_5	386456.JQKN01000019_gene1317	4.616e-73	252.0	COG0638@1|root,arCOG00970@2157|Archaea,2XUIZ@28890|Euryarchaeota,23NYV@183925|Methanobacteria	183925|Methanobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	psmB	-	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
LZS1_k127_6140157_15	309803.CTN_1885	4.354e-20	94.0	COG2201@1|root,COG2201@2|Bacteria,2GCZV@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
LZS1_k127_6140157_11	351160.RCIX2113	1.399e-25	113.0	COG0784@1|root,arCOG03799@1|root,arCOG06712@1|root,arCOG02393@2157|Archaea,arCOG03799@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Anticodon_1,DUF835,GAF_2,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_9,Response_reg,zinc_ribbon_2
LZS1_k127_6140157_14	1236689.MMALV_09130	1.705e-22	113.0	arCOG01814@1|root,arCOG01814@2157|Archaea,2XT74@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6140157_4	1041930.Mtc_0365	4.893e-89	317.0	COG4962@1|root,arCOG01818@2157|Archaea,2XTN5@28890|Euryarchaeota,2N9AG@224756|Methanomicrobia	224756|Methanomicrobia	N	Type II/IV secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
LZS1_k127_6140157_16	1121945.ATXS01000001_gene2455	2.668e-19	93.0	COG1325@1|root,arCOG01042@2157|Archaea,2Y01Q@28890|Euryarchaeota,23VKT@183963|Halobacteria	183963|Halobacteria	J	exosome subunit	-	-	-	ko:K07581	-	-	-	-	ko00000	-	-	-	RNA_binding
LZS1_k127_6140157_8	673860.AciM339_0766	7.081e-55	202.0	COG1014@1|root,arCOG01603@2157|Archaea,2XVFR@28890|Euryarchaeota,3F2RB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.7.1,1.2.7.7	ko:K00172,ko:K00189	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
LZS1_k127_6140157_12	1183377.Py04_1081	1.106e-24	106.0	COG1144@1|root,arCOG01605@2157|Archaea,2XY2F@28890|Euryarchaeota,245HQ@183968|Thermococci	183968|Thermococci	C	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity	vorD	-	1.2.7.7	ko:K00188	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	Fer4
LZS1_k127_6140157_1	673860.AciM339_0764	1.561e-154	501.0	COG0674@1|root,arCOG01608@2157|Archaea,2XTB0@28890|Euryarchaeota,3F36A@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorA	-	1.2.7.1,1.2.7.7	ko:K00169,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
LZS1_k127_6140157_2	439481.Aboo_0301	4.1e-114	381.0	COG1013@1|root,arCOG01601@2157|Archaea,2XT3E@28890|Euryarchaeota,3F2JH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorB	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
LZS1_k127_6140157_3	593750.Metfor_0088	5.797e-93	320.0	COG3199@1|root,arCOG01350@2157|Archaea,2XUIQ@28890|Euryarchaeota	28890|Euryarchaeota	S	ATP-NAD AcoX kinase	-	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
LZS1_k127_6140157_10	1202768.JROF01000002_gene117	3.85e-44	175.0	COG0206@1|root,arCOG02201@2157|Archaea,2XSV8@28890|Euryarchaeota,23TS5@183963|Halobacteria	183963|Halobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ2	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS1_k127_6140157_0	1236689.MMALV_09230	0.0	1042.0	COG0495@1|root,arCOG00809@2157|Archaea,2XU7M@28890|Euryarchaeota,3F2EY@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1g
LZS1_k127_6140157_7	572478.Vdis_0046	2.143e-56	205.0	COG0163@1|root,arCOG01703@2157|Archaea,2XQJ7@28889|Crenarchaeota	28889|Crenarchaeota	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
LZS1_k127_6140157_9	589924.Ferp_0033	7.399e-46	169.0	COG2238@1|root,arCOG01344@2157|Archaea,2XXA6@28890|Euryarchaeota,24658@183980|Archaeoglobi	183980|Archaeoglobi	J	May be involved in maturation of the 30S ribosomal subunit	rps19e	-	-	ko:K02966	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19e
LZS1_k127_6140157_13	351160.RCIX1046	1.213e-23	103.0	COG2118@1|root,arCOG04179@2157|Archaea,2XZUR@28890|Euryarchaeota,2N9ZR@224756|Methanomicrobia	224756|Methanomicrobia	S	Belongs to the PDCD5 family	-	-	-	ko:K06875	-	-	-	-	ko00000	-	-	-	dsDNA_bind
LZS1_k127_6140157_17	69014.TK1319	2.118e-12	71.0	COG2167@1|root,arCOG04177@2157|Archaea,2XZSY@28890|Euryarchaeota,244NC@183968|Thermococci	183968|Thermococci	J	Belongs to the eukaryotic ribosomal protein eL39 family	rpl39e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02924	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L39
LZS1_k127_6164913_1	215803.DB30_6617	3.342e-26	121.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YWZJ@29|Myxococcales	28221|Deltaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,REJ
LZS1_k127_6164913_0	439481.Aboo_0620	3.643e-40	165.0	arCOG02497@1|root,arCOG02497@2157|Archaea	2157|Archaea	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,NosD
LZS1_k127_6164913_2	1123252.ATZF01000005_gene4045	1.022e-14	83.0	COG2852@1|root,COG2852@2|Bacteria,1UWWJ@1239|Firmicutes,4IC6S@91061|Bacilli,27D4Y@186824|Thermoactinomycetaceae	91061|Bacilli	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
LZS1_k127_6164913_3	436308.Nmar_1678	0.0001659	47.0	COG3794@1|root,arCOG02926@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
LZS1_k127_6165582_1	1379698.RBG1_1C00001G1795	5.984e-111	370.0	COG0160@1|root,COG0160@2|Bacteria,2NNRV@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-III	argD	-	2.6.1.19,2.6.1.33,2.6.1.36	ko:K00823,ko:K03918,ko:K20428	ko00250,ko00410,ko00525,ko00640,ko00650,ko01100,ko01120,ko01130,map00250,map00410,map00525,map00640,map00650,map01100,map01120,map01130	M00027	R00457,R00908,R01648,R02773	RC00006,RC00062,RC00781	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_6165582_6	1236689.MMALV_02530	1.558e-06	55.0	arCOG06958@1|root,arCOG06958@2157|Archaea,2Y41U@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6165582_3	1122138.AQUZ01000064_gene5361	8.302e-42	178.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
LZS1_k127_6165582_0	368407.Memar_0604	2.228e-113	375.0	COG3276@1|root,arCOG01564@2157|Archaea,2XWBV@28890|Euryarchaeota,2N945@224756|Methanomicrobia	224756|Methanomicrobia	J	PFAM elongation factor Tu domain 2	-	-	-	-	-	-	-	-	-	-	-	-	GTP_EFTU_D2
LZS1_k127_6165582_2	1173028.ANKO01000018_gene1202	3.463e-42	172.0	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria,1G3QU@1117|Cyanobacteria,1HAPS@1150|Oscillatoriales	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,PPC,Peptidase_C11
LZS1_k127_6165582_5	1123508.JH636439_gene1132	3.255e-15	88.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
LZS1_k127_6165582_4	459349.CLOAM0953	3.667e-37	151.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS1_k127_6175008_8	1459636.NTE_01116	1.639e-33	132.0	arCOG03769@1|root,arCOG03769@2157|Archaea	2157|Archaea	M	glucosylceramidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6175008_15	673860.AciM339_0453	6.914e-14	84.0	arCOG13530@1|root,arCOG13530@2157|Archaea,2Y727@28890|Euryarchaeota,3F38E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6175008_2	104623.Ser39006_02654	5.499e-79	276.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
LZS1_k127_6175008_18	436308.Nmar_1016	0.0001065	51.0	arCOG09752@1|root,arCOG09752@2157|Archaea,41T9M@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6175008_17	555079.Toce_1935	3.069e-06	55.0	COG5015@1|root,COG5015@2|Bacteria,1V4P5@1239|Firmicutes,25D0I@186801|Clostridia,42IBI@68295|Thermoanaerobacterales	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
LZS1_k127_6175008_4	69014.TK0704	5.034e-72	249.0	COG0500@1|root,arCOG01773@2157|Archaea,2XXKU@28890|Euryarchaeota,242K9@183968|Thermococci	183968|Thermococci	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3216,Methyltransf_11
LZS1_k127_6175008_3	985053.VMUT_2339	1.12e-73	263.0	COG0247@1|root,COG2048@1|root,arCOG00964@2157|Archaea,arCOG05014@2157|Archaea	2157|Archaea	C	Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane	hdrE	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0031224,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0044425,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576	1.8.98.1	ko:K08265,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	Fer4_17,Nitrate_red_gam
LZS1_k127_6175008_0	985053.VMUT_2341	2.824e-179	582.0	COG1148@1|root,arCOG02235@2157|Archaea,2XS2Y@28889|Crenarchaeota	985053.VMUT_2341|-	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	-
LZS1_k127_6175008_1	985053.VMUT_2342	3.474e-170	548.0	COG1148@1|root,arCOG02235@2157|Archaea,2XS2Y@28889|Crenarchaeota	28889|Crenarchaeota	C	Pyridine nucleotide-disulphide oxidoreductase	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
LZS1_k127_6175008_6	1121472.AQWN01000008_gene1912	3.107e-34	136.0	COG1908@1|root,COG1908@2|Bacteria,1V80C@1239|Firmicutes,24MB7@186801|Clostridia,264Z4@186807|Peptococcaceae	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
LZS1_k127_6175008_11	985053.VMUT_2344	4.537e-28	115.0	COG0425@1|root,arCOG02062@2157|Archaea	2157|Archaea	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,TusA
LZS1_k127_6175008_5	1156937.MFUM_550026	4.09e-36	142.0	COG2210@1|root,COG2210@2|Bacteria,46ZAV@74201|Verrucomicrobia,37GMZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
LZS1_k127_6175008_14	457570.Nther_0036	1.068e-24	115.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia	186801|Clostridia	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
LZS1_k127_6175008_10	1173024.KI912148_gene3735	2.555e-30	124.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	ychN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
LZS1_k127_6175008_7	985053.VMUT_1872	1.373e-33	143.0	COG3371@1|root,arCOG02008@2157|Archaea,2XRYZ@28889|Crenarchaeota	28889|Crenarchaeota	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
LZS1_k127_6175008_9	416591.Tlet_1577	1.024e-31	129.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
LZS1_k127_6175008_13	415426.Hbut_1112	1.425e-25	109.0	COG0727@1|root,arCOG02579@2157|Archaea,2XR8B@28889|Crenarchaeota	28889|Crenarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
LZS1_k127_6175008_16	1033736.CAHK01000013_gene1037	1.54e-08	66.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4F93H@85019|Brevibacteriaceae	201174|Actinobacteria	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
LZS1_k127_6175008_12	1125863.JAFN01000001_gene752	2.341e-27	116.0	COG1917@1|root,COG1917@2|Bacteria,1N2JS@1224|Proteobacteria,42TR3@68525|delta/epsilon subdivisions,2WQ4M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS1_k127_6184975_0	1487923.DP73_08235	2.76e-22	106.0	COG5598@1|root,COG5598@2|Bacteria,1V0ZE@1239|Firmicutes,24D6Y@186801|Clostridia,266YG@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
LZS1_k127_6209323_4	1236689.MMALV_13680	2.24e-13	78.0	COG0583@1|root,arCOG00225@2157|Archaea,2XYM3@28890|Euryarchaeota	28890|Euryarchaeota	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1
LZS1_k127_6209323_2	1236689.MMALV_13670	8.898e-55	197.0	COG2048@1|root,arCOG00964@2157|Archaea,2XZ7E@28890|Euryarchaeota,3F2WA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
LZS1_k127_6209323_0	1054217.TALC_01276	2.5e-107	354.0	COG2048@1|root,arCOG00338@2157|Archaea,2XTWJ@28890|Euryarchaeota,242CE@183967|Thermoplasmata	183967|Thermoplasmata	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00241,ko:K03389	ko00020,ko00190,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00356,M00357,M00374,M00376,M00563,M00567	R02164,R04540,R11928,R11931,R11943,R11944	RC00011,RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
LZS1_k127_6209323_5	868131.MSWAN_1551	8.185e-05	48.0	COG4009@1|root,arCOG04905@2157|Archaea,2Y0I1@28890|Euryarchaeota,23P7W@183925|Methanobacteria	183925|Methanobacteria	S	Domain of unknown function (DUF749)	-	-	-	-	-	-	-	-	-	-	-	-	DUF749
LZS1_k127_6209323_1	1121377.KB906425_gene282	2.814e-92	322.0	COG0624@1|root,COG0624@2|Bacteria,1WIRQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS1_k127_6209323_3	862751.SACTE_4891	3.502e-17	97.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria	201174|Actinobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_6211954_1	309798.COPRO5265_0132	2.275e-11	64.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,42F6C@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS1_k127_6211954_0	351160.LRC332	1.484e-20	101.0	arCOG01190@1|root,arCOG01190@2157|Archaea	351160.LRC332|-	G	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6211954_2	591019.Shell_0225	7.808e-10	64.0	COG0675@1|root,arCOG00679@2157|Archaea,2XRYA@28889|Crenarchaeota	28889|Crenarchaeota	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
LZS1_k127_6211954_3	994573.T472_0207650	6.509e-08	60.0	COG1633@1|root,COG1633@2|Bacteria,1V4P6@1239|Firmicutes,24IYH@186801|Clostridia,36J9Q@31979|Clostridiaceae	186801|Clostridia	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS1_k127_6274627_2	1343739.PAP_04280	3.24e-22	103.0	COG1308@1|root,arCOG04061@2157|Archaea,2XXYV@28890|Euryarchaeota,244FN@183968|Thermococci	183968|Thermococci	J	Contacts the emerging nascent chain on the ribosome	nac	-	-	ko:K03626	-	-	-	-	ko00000	-	-	-	NAC
LZS1_k127_6274627_4	426368.MmarC7_1699	2.442e-05	53.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,23RCX@183939|Methanococci	183939|Methanococci	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
LZS1_k127_6274627_1	351160.RCIX953	8.349e-38	151.0	COG0561@1|root,arCOG01213@2157|Archaea,2XX94@28890|Euryarchaeota,2N9JY@224756|Methanomicrobia	224756|Methanomicrobia	G	Catalyzes the dephosphorylation of 2-phosphoglycolate	-	-	3.1.3.18	ko:K22223	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
LZS1_k127_6274627_0	673860.AciM339_0290	1.08e-94	319.0	COG1469@1|root,arCOG04301@2157|Archaea,2XT11@28890|Euryarchaeota,3F2JX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin	mptA	GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682	3.5.4.39	ko:K17488	ko00790,map00790	-	R10348	RC02504,RC03131	ko00000,ko00001,ko01000	-	-	-	GCHY-1
LZS1_k127_6274627_3	573064.Mefer_1155	6.493e-10	63.0	COG0164@1|root,arCOG04121@2157|Archaea,2XWYC@28890|Euryarchaeota,23QZE@183939|Methanococci	183939|Methanococci	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS1_k127_6292005_1	1054217.TALC_01295	2.922e-31	124.0	COG1759@1|root,arCOG04346@2157|Archaea,2XUFR@28890|Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates	purP	-	6.3.4.23	ko:K06863	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R06975	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1246,DUF1297
LZS1_k127_6292005_0	1236689.MMALV_03830	4.243e-44	168.0	arCOG14795@1|root,arCOG14795@2157|Archaea,2Y31Z@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6354708_1	1286171.EAL2_c03680	1.329e-97	322.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25V2P@186806|Eubacteriaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
LZS1_k127_6354708_4	370438.PTH_0378	8.476e-60	225.0	COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia,261F2@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM geranylgeranyl reductase family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl
LZS1_k127_6354708_2	1236689.MMALV_01840	6.228e-78	273.0	COG2520@1|root,arCOG10124@2157|Archaea,2XTPV@28890|Euryarchaeota,3F2KV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Met-10+ like-protein	taw2	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.5.1.114	ko:K07055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Met_10
LZS1_k127_6354708_6	1236689.MMALV_01850	1.989e-42	174.0	arCOG05338@1|root,arCOG05338@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6354708_7	1094980.Mpsy_2611	1.523e-24	112.0	COG0745@1|root,arCOG02348@1|root,arCOG03799@1|root,arCOG02348@2157|Archaea,arCOG02592@2157|Archaea,arCOG03799@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF835)	-	-	2.7.7.65,6.3.4.2	ko:K01937,ko:K02488	ko00240,ko01100,ko02020,ko04112,map00240,map01100,map02020,map04112	M00052,M00511	R00571,R00573,R08057	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	DUF835,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_6354708_0	1123274.KB899407_gene178	5.141e-104	341.0	COG0450@1|root,COG0450@2|Bacteria,2J6HG@203691|Spirochaetes	203691|Spirochaetes	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
LZS1_k127_6354708_9	485913.Krac_8842	4.148e-08	62.0	COG0143@1|root,COG0143@2|Bacteria,2G6VG@200795|Chloroflexi	200795|Chloroflexi	J	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
LZS1_k127_6354708_10	237368.SCABRO_03564	5.793e-08	66.0	COG3291@1|root,COG3291@2|Bacteria,2J1GZ@203682|Planctomycetes	203682|Planctomycetes	U	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
LZS1_k127_6354708_5	1499967.BAYZ01000132_gene305	2.083e-57	213.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_6354708_3	1304874.JAFY01000002_gene134	7.261e-65	241.0	COG1173@1|root,COG1173@2|Bacteria,3T9XU@508458|Synergistetes	508458|Synergistetes	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_6354708_8	700508.D174_02535	2.777e-24	117.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,23EV8@1762|Mycobacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_6457174_0	351160.LRC381	5.819e-100	343.0	COG4608@1|root,arCOG00184@2157|Archaea,2Y5BH@28890|Euryarchaeota,2N9H8@224756|Methanomicrobia	224756|Methanomicrobia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iAF692.Mbar_A0472	ABC_tran,oligo_HPY
LZS1_k127_6457174_3	673860.AciM339_0749	4.58e-66	246.0	COG0517@1|root,COG0750@1|root,arCOG00607@2157|Archaea,arCOG04064@2157|Archaea,2XSZP@28890|Euryarchaeota,3F2KK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
LZS1_k127_6457174_2	419665.Maeo_0293	4.561e-71	250.0	COG0613@1|root,arCOG00302@2157|Archaea,2XSWE@28890|Euryarchaeota,23QJ2@183939|Methanococci	183939|Methanococci	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP_C
LZS1_k127_6457174_1	335543.Sfum_3448	2.987e-80	274.0	COG1145@1|root,COG1145@2|Bacteria,1PW12@1224|Proteobacteria,42MZ9@68525|delta/epsilon subdivisions,2WN0W@28221|Deltaproteobacteria,2MR02@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
LZS1_k127_6457174_4	255470.cbdbA1633	0.0006963	48.0	2A4DT@1|root,30SZM@2|Bacteria,2GAV3@200795|Chloroflexi,34DER@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6463158_5	589924.Ferp_2240	1.561e-26	112.0	COG0526@1|root,arCOG01972@2157|Archaea,2XXRJ@28890|Euryarchaeota,2466S@183980|Archaeoglobi	183980|Archaeoglobi	O	PFAM Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS1_k127_6463158_3	673860.AciM339_0975	4.396e-45	172.0	COG2178@1|root,arCOG04318@2157|Archaea,2XYD0@28890|Euryarchaeota,3F2TB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	RNA-binding protein of the translin family	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	Translin
LZS1_k127_6463158_1	1236689.MMALV_16330	4.401e-150	486.0	COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,3F2H0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Phosphoribosylglycinamide synthetase, C domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A3513	GARS_A,GARS_C,GARS_N
LZS1_k127_6463158_2	1151117.AJLF01000001_gene1273	3.729e-129	430.0	COG0252@1|root,arCOG01924@2157|Archaea,2XTN1@28890|Euryarchaeota,2439K@183968|Thermococci	183968|Thermococci	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatD	-	6.3.5.7	ko:K09482	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	Asparaginase
LZS1_k127_6463158_0	1236689.MMALV_16300	7.529e-185	597.0	COG2511@1|root,arCOG01719@2157|Archaea,2XT73@28890|Euryarchaeota,3F2IW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
LZS1_k127_6463158_4	1343739.PAP_00760	3.91e-38	150.0	COG2890@1|root,arCOG00109@2157|Archaea,2XWJZ@28890|Euryarchaeota,242YQ@183968|Thermococci	183968|Thermococci	Q	Pfam:Methyltransf_26	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
LZS1_k127_6463158_6	1242864.D187_002187	1.582e-20	102.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS1_k127_6470845_0	247490.KSU1_C1370	1.837e-216	683.0	COG0443@1|root,COG0443@2|Bacteria,2IWWS@203682|Planctomycetes	203682|Planctomycetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS1_k127_6470845_1	1121472.AQWN01000002_gene2159	1.921e-116	386.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,260FH@186807|Peptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS1_k127_6470845_14	673860.AciM339_0750	2.056e-30	131.0	arCOG03142@1|root,arCOG03142@2157|Archaea,2XTSE@28890|Euryarchaeota,3F38F@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6470845_5	751944.HALDL1_07090	9.712e-87	299.0	COG3407@1|root,arCOG02937@2157|Archaea,2XUJ7@28890|Euryarchaeota,23T1T@183963|Halobacteria	183963|Halobacteria	I	COG3407 Mevalonate pyrophosphate decarboxylase	mvaD	-	4.1.1.99	ko:K17942	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10561	RC00453	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS1_k127_6470845_16	1236689.MMALV_15270	3.608e-27	115.0	COG1371@1|root,arCOG04055@2157|Archaea,2Y6XM@28890|Euryarchaeota,3F2S4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	-	-	-	-	-	-	-	-	-	-	-	Archease
LZS1_k127_6470845_10	316274.Haur_2402	4.791e-54	198.0	COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi,375YQ@32061|Chloroflexia	32061|Chloroflexia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
LZS1_k127_6470845_13	415426.Hbut_0409	6.277e-44	177.0	COG0312@1|root,arCOG00322@2157|Archaea,2XQP6@28889|Crenarchaeota	28889|Crenarchaeota	S	modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS1_k127_6470845_3	1042877.GQS_01610	6.837e-106	359.0	COG1530@1|root,arCOG00321@2157|Archaea,2XU9U@28890|Euryarchaeota,242NX@183968|Thermococci	183968|Thermococci	L	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS1_k127_6470845_8	1236689.MMALV_15260	1.05e-64	231.0	COG1712@1|root,arCOG00254@2157|Archaea,2XXKF@28890|Euryarchaeota,3F2RC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Domain of unknown function DUF108	nadX	-	1.4.1.21,5.3.3.2	ko:K01823,ko:K06989	ko00760,ko00900,ko01100,ko01110,ko01130,map00760,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123,R07407,R07410	RC00455,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF108,NAD_binding_3
LZS1_k127_6470845_4	673860.AciM339_0595	9.108e-96	325.0	COG0006@1|root,arCOG01000@2157|Archaea,2XTI9@28890|Euryarchaeota,3F2JJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Belongs to the peptidase M24B family	pepQ1	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
LZS1_k127_6470845_7	224325.AF_0130	4.324e-68	245.0	COG0123@1|root,arCOG00324@2157|Archaea,2XT0B@28890|Euryarchaeota,246V5@183980|Archaeoglobi	183980|Archaeoglobi	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS1_k127_6470845_17	717231.Flexsi_1530	9.209e-08	64.0	COG0517@1|root,COG0517@2|Bacteria,2GEQ8@200930|Deferribacteres	2|Bacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767,ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
LZS1_k127_6470845_2	1054217.TALC_01405	2.246e-116	389.0	COG0126@1|root,arCOG00496@2157|Archaea,2XSXX@28890|Euryarchaeota,241MF@183967|Thermoplasmata	183967|Thermoplasmata	F	phosphoglycerate kinase activity	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
LZS1_k127_6470845_9	673860.AciM339_1539	3.347e-60	214.0	COG0856@1|root,arCOG00028@2157|Archaea,2XU2R@28890|Euryarchaeota,3F30G@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	pyrE1	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS1_k127_6470845_11	1183377.Py04_1355	2.59e-52	196.0	COG1893@1|root,arCOG04139@2157|Archaea,2XTBD@28890|Euryarchaeota,243P9@183968|Thermococci	183968|Thermococci	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS1_k127_6470845_15	439481.Aboo_1309	1.979e-27	123.0	COG1989@1|root,arCOG02298@2157|Archaea,2Y6ZX@28890|Euryarchaeota,3F315@33867|unclassified Euryarchaeota	28890|Euryarchaeota	N	Archaeal Peptidase A24 C-terminus Type II	-	-	3.4.23.52	ko:K07991	-	-	-	-	ko00000,ko01000,ko01002,ko02035,ko02044	-	-	-	Arc_PepC_II
LZS1_k127_6470845_12	648996.Theam_1436	2.793e-52	195.0	COG2231@1|root,COG2231@2|Bacteria,2G41H@200783|Aquificae	200783|Aquificae	L	PFAM HhH-GPD family protein	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
LZS1_k127_6470845_6	439481.Aboo_1455	1.714e-82	281.0	COG1180@1|root,arCOG00946@2157|Archaea,2XUB7@28890|Euryarchaeota,3F2I4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Radical SAM	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_6479368_1	673860.AciM339_0904	5.311e-94	315.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTRS@28890|Euryarchaeota,3F37Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS1_k127_6479368_2	565033.GACE_1144	1.991e-88	313.0	COG0381@1|root,arCOG01392@2157|Archaea,2XU0B@28890|Euryarchaeota,246S6@183980|Archaeoglobi	183980|Archaeoglobi	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS1_k127_6479368_0	593117.TGAM_2142	2.731e-105	354.0	COG0438@1|root,arCOG01403@2157|Archaea,2XWEJ@28890|Euryarchaeota,243T2@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS1_k127_6579363_0	394503.Ccel_1554	1.33e-47	185.0	COG1387@1|root,COG1387@2|Bacteria,1VUGT@1239|Firmicutes,25F7D@186801|Clostridia,36UY8@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,DUF3604
LZS1_k127_6579363_1	521011.Mpal_0671	3.926e-45	173.0	arCOG02576@1|root,arCOG02576@2157|Archaea,2XZNM@28890|Euryarchaeota,2N9WU@224756|Methanomicrobia	224756|Methanomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
LZS1_k127_6599129_3	1459636.NTE_03463	2.834e-35	139.0	COG1055@1|root,arCOG00238@2157|Archaea	2157|Archaea	P	Citrate transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	CitMHS,Na_sulph_symp
LZS1_k127_6599129_1	529709.PYCH_07400	1.951e-119	407.0	COG1293@1|root,arCOG01695@2157|Archaea,2XTMF@28890|Euryarchaeota,243BD@183968|Thermococci	183968|Thermococci	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
LZS1_k127_6599129_2	316274.Haur_1627	2.507e-81	279.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,374VN@32061|Chloroflexia	32061|Chloroflexia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
LZS1_k127_6599129_0	1125863.JAFN01000001_gene2044	3.007e-220	702.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
LZS1_k127_6599129_4	591019.Shell_0225	6.2e-10	64.0	COG0675@1|root,arCOG00679@2157|Archaea,2XRYA@28889|Crenarchaeota	28889|Crenarchaeota	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
LZS1_k127_6600795_0	439481.Aboo_0964	2.961e-68	237.0	COG0206@1|root,arCOG02201@2157|Archaea,2XTMW@28890|Euryarchaeota,3F31W@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ1	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS1_k127_6600795_1	368408.Tpen_1052	4.616e-22	99.0	COG1254@1|root,arCOG01674@2157|Archaea,2XR8S@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
LZS1_k127_6600795_2	1341151.ASZU01000004_gene497	6.25e-08	63.0	COG0477@1|root,COG2814@2|Bacteria,1UI43@1239|Firmicutes,4ISCR@91061|Bacilli,27BDF@186824|Thermoactinomycetaceae	91061|Bacilli	EGP	Major Facilitator Superfamily	yqgE	-	-	ko:K08222	-	-	-	-	ko00000,ko02000	2.A.1.33	-	-	MFS_1
LZS1_k127_6684065_4	1089551.KE386572_gene1743	1.091e-28	128.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,2U12Y@28211|Alphaproteobacteria,4BRG6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
LZS1_k127_6684065_2	589924.Ferp_1301	1.351e-71	248.0	COG1720@1|root,arCOG00761@2157|Archaea,2XY3D@28890|Euryarchaeota,246RS@183980|Archaeoglobi	183980|Archaeoglobi	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
LZS1_k127_6684065_3	1236689.MMALV_06180	2.228e-62	221.0	arCOG01806@1|root,arCOG01806@2157|Archaea,2Y0PI@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ACT_7
LZS1_k127_6684065_1	574087.Acear_1530	6.541e-126	421.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3WA9V@53433|Halanaerobiales	186801|Clostridia	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
LZS1_k127_6684065_0	1178540.BA70_19070	6.517e-141	457.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli,1ZC1P@1386|Bacillus	91061|Bacilli	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04675	Arginosuc_synth
LZS1_k127_6692839_4	1236689.MMALV_02180	1.366e-12	71.0	COG1354@1|root,arCOG02610@2157|Archaea,2XZHK@28890|Euryarchaeota,3F2QG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	chromosome segregation and condensation protein ScpA	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
LZS1_k127_6692839_2	439481.Aboo_1099	6.745e-35	139.0	COG1386@1|root,arCOG02613@2157|Archaea,2XZ7Q@28890|Euryarchaeota,3F2S6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	TIGRFAM segregation and condensation protein B	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
LZS1_k127_6692839_3	273116.14325338	3.56e-23	100.0	COG1958@1|root,arCOG00998@2157|Archaea,2Y0B2@28890|Euryarchaeota,242CV@183967|Thermoplasmata	183967|Thermoplasmata	K	snRNP Sm proteins	-	-	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
LZS1_k127_6692839_0	935948.KE386495_gene1236	2.617e-63	233.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,42EZG@68295|Thermoanaerobacterales	186801|Clostridia	M	Transferase hexapeptide repeat	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS1_k127_6692839_1	1459636.NTE_00865	2.838e-44	163.0	COG0306@1|root,arCOG02267@2157|Archaea,41SD8@651137|Thaumarchaeota	651137|Thaumarchaeota	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS1_k127_6698322_0	1120973.AQXL01000095_gene239	1.29e-30	136.0	COG2271@1|root,COG2271@2|Bacteria,1V1ZE@1239|Firmicutes,4HHGH@91061|Bacilli,278SS@186823|Alicyclobacillaceae	91061|Bacilli	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_6698322_1	1304874.JAFY01000002_gene577	2.506e-18	91.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_6709284_2	1071085.KK033114_gene1079	2.931e-09	63.0	COG1931@1|root,arCOG01043@2157|Archaea,2XWHA@28890|Euryarchaeota,23VAH@183963|Halobacteria	183963|Halobacteria	S	Belongs to the UPF0201 family	-	-	-	ko:K09736	-	-	-	-	ko00000	-	-	-	RNA_binding
LZS1_k127_6709284_0	1236689.MMALV_00180	4.065e-37	150.0	COG1082@1|root,arCOG01895@2157|Archaea,2XUTU@28890|Euryarchaeota	28890|Euryarchaeota	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS1_k127_6709284_1	673860.AciM339_0394	1.524e-14	80.0	arCOG05363@1|root,arCOG05363@2157|Archaea,2Y07M@28890|Euryarchaeota,3F2V9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
LZS1_k127_6722042_0	1094980.Mpsy_2688	2.763e-131	433.0	COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,2N92Y@224756|Methanomicrobia	224756|Methanomicrobia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS1_k127_6764430_2	523850.TON_0714	4.212e-63	220.0	COG1690@1|root,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,24310@183968|Thermococci	183968|Thermococci	J	tRNA-splicing ligase that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs	rtcB	GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,LAGLIDADG_3,RtcB
LZS1_k127_6764430_0	673860.AciM339_1458	1.09e-111	377.0	COG1078@1|root,arCOG04430@2157|Archaea,2XUT7@28890|Euryarchaeota,3F2H2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
LZS1_k127_6764430_7	858215.Thexy_0303	9.486e-12	74.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,42EW9@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
LZS1_k127_6764430_5	439481.Aboo_0757	2.857e-29	124.0	COG2450@1|root,arCOG02263@2157|Archaea,2XXYF@28890|Euryarchaeota,3F3BW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	D	Pfam:DUF552	sepF	-	-	ko:K09152	-	-	-	-	ko00000	-	-	-	SepF
LZS1_k127_6764430_4	1236689.MMALV_03850	5.876e-46	177.0	COG2016@1|root,arCOG00985@2157|Archaea,2XX1R@28890|Euryarchaeota,3F2SI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K07575	-	-	-	-	ko00000	-	-	-	DUF1947,PUA
LZS1_k127_6764430_3	192952.MM_0178	2.101e-46	191.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAF9@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
LZS1_k127_6764430_8	401526.TcarDRAFT_2685	1.722e-11	76.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS1_k127_6764430_9	304371.MCP_1387	7.865e-10	68.0	COG2202@1|root,arCOG06712@1|root,arCOG06515@2157|Archaea,arCOG06712@2157|Archaea,2Y7SX@28890|Euryarchaeota,2NBM4@224756|Methanomicrobia	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,PAS,PAS_3,PAS_4,PAS_8,PAS_9
LZS1_k127_6764430_6	304371.MCP_1156	6.699e-24	111.0	COG0784@1|root,arCOG02391@2157|Archaea,2Y6EC@28890|Euryarchaeota,2NBEQ@224756|Methanomicrobia	224756|Methanomicrobia	T	Response regulator receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
LZS1_k127_6764430_1	673860.AciM339_0510	3.106e-101	338.0	COG0371@1|root,arCOG00982@2157|Archaea,2XT0F@28890|Euryarchaeota,3F2IT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
LZS1_k127_67655_0	673860.AciM339_0753	4.109e-190	658.0	COG1287@1|root,arCOG02044@2157|Archaea,arCOG05365@2157|Archaea,2Y7QJ@28890|Euryarchaeota,3F2NE@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Carboxypeptidase regulatory-like domain	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	CarboxypepD_reg,PMT_2,STT3
LZS1_k127_67655_1	273075.Ta1135	0.0003331	51.0	arCOG05366@1|root,arCOG05366@2157|Archaea,2Y11W@28890|Euryarchaeota,241WB@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
LZS1_k127_6789153_0	439481.Aboo_1343	1.762e-58	209.0	COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota	28890|Euryarchaeota	C	aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
LZS1_k127_6789153_1	391623.TERMP_00596	2.475e-46	179.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT0T@28890|Euryarchaeota,242X5@183968|Thermococci	183968|Thermococci	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS1_k127_68929_1	673860.AciM339_0553	1.887e-30	121.0	COG1522@1|root,arCOG01117@2157|Archaea,2XZY2@28890|Euryarchaeota,3F3G3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
LZS1_k127_68929_0	644281.MFS40622_1675	4.208e-51	196.0	COG0524@1|root,arCOG00014@2157|Archaea,2XU7Z@28890|Euryarchaeota,23QJY@183939|Methanococci	183939|Methanococci	G	Belongs to the carbohydrate kinase PfkB family	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.1.213,2.7.1.73	ko:K22026	ko00230,ko00240,map00230,map00240	-	R00513,R01131,R01228	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS1_k127_68929_2	161156.JQKW01000006_gene1308	4.475e-14	73.0	COG0499@1|root,COG0499@2|Bacteria,2GGXJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS1_k127_6935107_2	304371.MCP_1855	6.005e-40	153.0	COG1164@1|root,arCOG04758@2157|Archaea	2157|Archaea	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
LZS1_k127_6935107_0	673860.AciM339_0648	1.647e-240	756.0	COG1245@1|root,arCOG00187@2157|Archaea,2XSZE@28890|Euryarchaeota,3F2G2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	metal-binding domain in RNase L inhibitor, RLI	rli	GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K06174	-	-	-	-	ko00000,ko03009	-	-	-	ABC_tran,Fer4,RLI
LZS1_k127_6935107_1	562970.Btus_0015	1.506e-48	181.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,4HHD3@91061|Bacilli,278F1@186823|Alicyclobacillaceae	91061|Bacilli	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS1_k127_6935107_3	1236689.MMALV_08550	4.105e-32	137.0	COG0798@1|root,arCOG02190@2157|Archaea,2Y3BU@28890|Euryarchaeota	28890|Euryarchaeota	P	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
LZS1_k127_7124644_4	1236689.MMALV_12690	6.356e-09	57.0	COG4023@1|root,arCOG02957@2157|Archaea,2Y1AH@28890|Euryarchaeota,3F2U9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	U	but it may be involved in stabilization of the trimeric complex	secG	-	-	-	-	-	-	-	-	-	-	-	Sec61_beta
LZS1_k127_7124644_1	1041930.Mtc_0831	1.209e-20	96.0	COG0784@1|root,arCOG02391@2157|Archaea,2Y6EC@28890|Euryarchaeota,2NBEQ@224756|Methanomicrobia	224756|Methanomicrobia	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_7124644_0	211165.AJLN01000117_gene2947	4.181e-163	527.0	COG1190@1|root,COG1190@2|Bacteria,1G0SA@1117|Cyanobacteria,1JK3F@1189|Stigonemataceae	1117|Cyanobacteria	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN678.lysS	KTSC,tRNA-synt_2,tRNA_anti-codon
LZS1_k127_7124644_3	1078085.HMPREF1210_02549	1.877e-11	76.0	COG0454@1|root,COG0456@2|Bacteria,1TS4G@1239|Firmicutes,4HFDG@91061|Bacilli,26GTG@186818|Planococcaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS1_k127_7124644_2	399549.Msed_0510	6.561e-18	85.0	COG1013@1|root,arCOG01601@2157|Archaea,2XPTF@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
LZS1_k127_7135914_1	439481.Aboo_1487	8.269e-58	222.0	COG3390@1|root,arCOG02258@2157|Archaea,2Y7QP@28890|Euryarchaeota,3F2PB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	protein conserved in archaea	-	-	-	ko:K09746	-	-	-	-	ko00000	-	-	-	-
LZS1_k127_7135914_0	673860.AciM339_1381	4.212e-93	321.0	COG1599@1|root,arCOG01510@2157|Archaea,2XTGJ@28890|Euryarchaeota,3F2KP@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins	rpa1	-	-	ko:K07466	ko03030,ko03420,ko03430,ko03440,ko03460,map03030,map03420,map03430,map03440,map03460	M00288	-	-	ko00000,ko00001,ko00002,ko03000,ko03032,ko03400	-	-	-	-
LZS1_k127_7135914_2	867845.KI911784_gene292	6.813e-21	103.0	COG0500@1|root,COG2226@2|Bacteria,2G948@200795|Chloroflexi,376TJ@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS1_k127_7135914_5	224325.AF_1672	4.782e-09	63.0	COG4747@1|root,arCOG04444@2157|Archaea,2XXTI@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
LZS1_k127_7135914_3	306281.AJLK01000025_gene1702	2.184e-20	105.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1G3AC@1117|Cyanobacteria	1117|Cyanobacteria	OQ	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_C11,VCBS
LZS1_k127_7135914_4	673860.AciM339_0490	2.61e-12	68.0	arCOG13525@1|root,arCOG13525@2157|Archaea,2Y72N@28890|Euryarchaeota,3F3A7@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7178855_5	1236689.MMALV_08010	4.816e-18	87.0	COG2097@1|root,arCOG04473@2157|Archaea,2XYWX@28890|Euryarchaeota,3F2SS@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the ribosomal protein L31e family	rpl31e	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02910	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31e
LZS1_k127_7178855_2	673860.AciM339_0029	5.22e-52	191.0	COG1976@1|root,arCOG04176@2157|Archaea,2XU7N@28890|Euryarchaeota,3F2QF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex	eif6	GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904	-	ko:K03264	ko03008,map03008	-	-	-	ko00000,ko00001,ko03009,ko03012	-	-	-	eIF-6
LZS1_k127_7178855_1	673860.AciM339_0030	2.389e-60	214.0	COG2220@1|root,arCOG00497@2157|Archaea,2XZBG@28890|Euryarchaeota,3F2Q1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
LZS1_k127_7178855_7	334413.FMG_1025	0.0009521	49.0	COG4640@1|root,COG4640@2|Bacteria,1W43J@1239|Firmicutes,2571N@186801|Clostridia,22J2R@1570339|Peptoniphilaceae	186801|Clostridia	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7178855_0	439481.Aboo_1186	1.318e-69	250.0	COG2237@1|root,arCOG04151@2157|Archaea,2XTV5@28890|Euryarchaeota,3F2NQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF373)	-	-	-	ko:K08975	-	-	-	-	ko00000	-	-	-	DUF373
LZS1_k127_7178855_3	1054217.TALC_00902	7.331e-51	188.0	COG1634@1|root,arCOG04303@2157|Archaea,2XT8R@28890|Euryarchaeota,241R2@183967|Thermoplasmata	183967|Thermoplasmata	H	Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP)	mptE	-	2.7.6.3	ko:K07142	ko00790,map00790	-	R03503	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	MAF_flag10
LZS1_k127_7178855_4	673860.AciM339_0677	7.714e-26	111.0	arCOG03678@1|root,arCOG03677@2157|Archaea,2Y0K5@28890|Euryarchaeota,3F3D6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7178855_6	673860.AciM339_0677	2.203e-08	57.0	arCOG03678@1|root,arCOG03677@2157|Archaea,2Y0K5@28890|Euryarchaeota,3F3D6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7182140_0	429009.Adeg_1885	0.0	1067.0	COG1148@1|root,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia,42FJG@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
LZS1_k127_7182140_3	880072.Desac_0835	1.393e-56	223.0	COG1908@1|root,COG2512@1|root,COG1908@2|Bacteria,COG2512@2|Bacteria,1RCZY@1224|Proteobacteria,42TFE@68525|delta/epsilon subdivisions,2WPDR@28221|Deltaproteobacteria,2MRBM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
LZS1_k127_7182140_1	335543.Sfum_1179	6.202e-143	477.0	COG1148@1|root,COG1148@2|Bacteria,1PZ04@1224|Proteobacteria,42PT3@68525|delta/epsilon subdivisions,2WMJU@28221|Deltaproteobacteria,2MR5J@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
LZS1_k127_7182140_2	644281.MFS40622_0209	1.109e-138	452.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
LZS1_k127_7185005_3	673860.AciM339_1019	1.145e-34	136.0	COG1690@1|root,arCOG04246@2157|Archaea,2XTIC@28890|Euryarchaeota,3F2GK@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	tRNA-splicing ligase RtcB	rtcB	GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Intein_splicing,LAGLIDADG_3,RtcB
LZS1_k127_7185005_6	553177.CAPSP0001_1881	0.0007209	53.0	COG4260@1|root,COG4260@2|Bacteria,4NHXG@976|Bacteroidetes,1I0MU@117743|Flavobacteriia,1ERQM@1016|Capnocytophaga	976|Bacteroidetes	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT
LZS1_k127_7185005_2	673860.AciM339_0019	1.206e-40	175.0	COG0457@1|root,arCOG02493@1|root,arCOG02493@2157|Archaea,arCOG03038@2157|Archaea	2157|Archaea	KLT	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	HTH_24,PQQ_2,PQQ_3,TPR_12,TPR_16,TPR_2,TPR_8
LZS1_k127_7185005_4	673860.AciM339_0010	4.022e-06	58.0	COG1361@1|root,arCOG01917@1|root,arCOG05791@1|root,arCOG01917@2157|Archaea,arCOG02079@2157|Archaea,arCOG04400@2157|Archaea,arCOG05791@2157|Archaea,2Y1TH@28890|Euryarchaeota,3F2UJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DZR,zinc_ribbon_2
LZS1_k127_7185005_5	768670.Calni_0614	0.000134	47.0	COG0209@1|root,COG0209@2|Bacteria,2GERH@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
LZS1_k127_7185005_0	439481.Aboo_0158	8.561e-108	358.0	COG0448@1|root,arCOG00912@2157|Archaea,2XTI4@28890|Euryarchaeota,3F2GM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS1_k127_7185005_1	673860.AciM339_1443	1.54e-72	253.0	COG0608@1|root,arCOG00427@2157|Archaea,2XT8Y@28890|Euryarchaeota,3F2FV@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	DHHA1 domain	recJ	-	-	ko:K07463	-	-	-	-	ko00000	-	-	-	DHHA1
LZS1_k127_7185676_3	1128421.JAGA01000003_gene3053	2.923e-49	183.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg,dCache_1
LZS1_k127_7185676_0	643648.Slip_2076	8.41e-188	598.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42KA9@68298|Syntrophomonadaceae	186801|Clostridia	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
LZS1_k127_7185676_1	264732.Moth_1518	2.538e-97	327.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,42EK7@68295|Thermoanaerobacterales	186801|Clostridia	C	Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain	nfnA	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
LZS1_k127_7185676_2	368407.Memar_0242	1.215e-62	220.0	COG0842@1|root,arCOG01467@2157|Archaea,2XU41@28890|Euryarchaeota	28890|Euryarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS1_k127_7205363_0	439481.Aboo_0148	2.887e-70	243.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTRS@28890|Euryarchaeota,3F37Q@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS1_k127_7209640_3	247490.KSU1_C0515	3.091e-55	198.0	COG1063@1|root,COG1063@2|Bacteria,2J2DX@203682|Planctomycetes	203682|Planctomycetes	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS1_k127_7209640_5	530564.Psta_4080	0.0001707	49.0	COG1873@1|root,COG1873@2|Bacteria	2|Bacteria	S	PRC-barrel domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,DUF2171,MgtE_N,PRC
LZS1_k127_7209640_1	104623.Ser39006_02654	3.209e-77	271.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
LZS1_k127_7209640_0	1071085.KK033114_gene134	2.442e-144	470.0	COG0001@1|root,arCOG00918@2157|Archaea,2XTGR@28890|Euryarchaeota,23SE9@183963|Halobacteria	183963|Halobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_7209640_2	1304874.JAFY01000002_gene577	4.281e-66	244.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_7209640_4	1120973.AQXL01000095_gene239	9.56e-31	136.0	COG2271@1|root,COG2271@2|Bacteria,1V1ZE@1239|Firmicutes,4HHGH@91061|Bacilli,278SS@186823|Alicyclobacillaceae	91061|Bacilli	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_7214421_3	673860.AciM339_0955	1.446e-48	181.0	COG0613@1|root,arCOG00302@2157|Archaea,2XSWE@28890|Euryarchaeota,3F2NI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	DNA polymerase alpha chain like domain	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
LZS1_k127_7214421_8	693661.Arcve_1632	4.501e-12	71.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
LZS1_k127_7214421_2	1236689.MMALV_05030	4.264e-88	302.0	COG1537@1|root,arCOG01741@2157|Archaea,2XTQ4@28890|Euryarchaeota,3F2P2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity	pelA	GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008	-	ko:K06965	ko03015,map03015	-	-	-	ko00000,ko00001	-	-	-	eRF1_1,eRF1_2,eRF1_3
LZS1_k127_7214421_7	351160.RCIX1840	8.591e-19	93.0	COG0784@1|root,arCOG02391@2157|Archaea,2Y6EC@28890|Euryarchaeota,2NBEQ@224756|Methanomicrobia	224756|Methanomicrobia	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_7214421_0	479434.Sthe_1374	8.131e-117	387.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
LZS1_k127_7214421_4	1499967.BAYZ01000050_gene2853	3.572e-20	96.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdxB	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
LZS1_k127_7214421_5	1041930.Mtc_0960	6.798e-20	91.0	COG0526@1|root,arCOG02713@2157|Archaea,2Y18H@28890|Euryarchaeota,2NA1S@224756|Methanomicrobia	224756|Methanomicrobia	O	Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
LZS1_k127_7214421_10	593750.Metfor_2728	6.591e-06	53.0	arCOG03645@1|root,arCOG03645@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7214421_1	593750.Metfor_2724	1.492e-97	331.0	COG0701@1|root,arCOG02712@2157|Archaea,2XT2F@28890|Euryarchaeota,2NAE3@224756|Methanomicrobia	224756|Methanomicrobia	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
LZS1_k127_7214421_6	368407.Memar_0013	6.966e-19	91.0	COG0640@1|root,arCOG01680@2157|Archaea,2Y05Q@28890|Euryarchaeota,2NA1B@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM regulatory protein, ArsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
LZS1_k127_7214421_11	926566.Terro_2881	1.415e-05	57.0	COG4932@1|root,COG5276@1|root,COG4932@2|Bacteria,COG5276@2|Bacteria,3Y8ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
LZS1_k127_7214421_9	333138.LQ50_01770	3.623e-08	66.0	COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus	91061|Bacilli	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
LZS1_k127_7234332_4	1236689.MMALV_07840	7.055e-43	160.0	COG1901@1|root,arCOG01239@2157|Archaea,2XTSB@28890|Euryarchaeota,3F2S0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs	trmY	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.257	ko:K16317	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_2
LZS1_k127_7234332_6	439481.Aboo_0442	5.437e-11	71.0	COG0640@1|root,arCOG03067@2157|Archaea,2Y75A@28890|Euryarchaeota,3F3F6@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7234332_0	673860.AciM339_1488	9.989e-145	475.0	COG0015@1|root,arCOG01747@2157|Archaea,2XUQ5@28890|Euryarchaeota,3F2GT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
LZS1_k127_7234332_5	368407.Memar_2425	4.481e-16	78.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota,2NA39@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	-
LZS1_k127_7234332_3	1304874.JAFY01000002_gene134	4.679e-65	235.0	COG1173@1|root,COG1173@2|Bacteria,3T9XU@508458|Synergistetes	508458|Synergistetes	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_7234332_1	1001240.GY21_06040	2.511e-70	249.0	COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria,4FR2U@85023|Microbacteriaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_7234332_2	65497.JODV01000021_gene2130	9.485e-69	263.0	COG0747@1|root,COG0747@2|Bacteria,2GNKN@201174|Actinobacteria,4E0AJ@85010|Pseudonocardiales	201174|Actinobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_7251510_4	1150474.JQJI01000048_gene1242	7.119e-19	88.0	COG4608@1|root,COG4608@2|Bacteria,2GC6X@200918|Thermotogae	200918|Thermotogae	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS1_k127_7251510_0	673860.AciM339_1314	1.791e-95	332.0	COG0444@1|root,arCOG00181@2157|Archaea,2XSTM@28890|Euryarchaeota,3F38V@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	TIGRFAM oligopeptide dipeptide ABC transporter	oppD2	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS1_k127_7251510_2	439481.Aboo_1253	1.419e-79	276.0	COG1173@1|root,arCOG00748@2157|Archaea,2XUIX@28890|Euryarchaeota,3F32Y@33867|unclassified Euryarchaeota	28890|Euryarchaeota	P	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS1_k127_7251510_1	1501230.ET33_06925	2.684e-87	299.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HBED@91061|Bacilli,26RTC@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter permease	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_7251510_3	373903.Hore_04900	1.95e-46	180.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WB7X@53433|Halanaerobiales	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_7261600_2	304371.MCP_1358	3.755e-15	78.0	COG0175@1|root,COG2221@1|root,arCOG00073@2157|Archaea,arCOG02059@2157|Archaea,2Y7JD@28890|Euryarchaeota,2N9AR@224756|Methanomicrobia	224756|Methanomicrobia	E	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,PAPS_reduct
LZS1_k127_7261600_0	339860.Msp_1154	2.187e-39	154.0	COG1994@1|root,arCOG00614@2157|Archaea,2XX7B@28890|Euryarchaeota,23P2G@183925|Methanobacteria	183925|Methanobacteria	S	PFAM Peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7261600_1	1236689.MMALV_13780	7.618e-30	122.0	COG0277@1|root,arCOG00337@2157|Archaea,2XT5C@28890|Euryarchaeota	28890|Euryarchaeota	C	COG0277 FAD FMN-containing dehydrogenases	glcD2	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104,ko:K06911	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
LZS1_k127_7273619_1	648757.Rvan_1972	0.0004293	44.0	COG3449@1|root,COG3449@2|Bacteria,1RF2U@1224|Proteobacteria,2UBIJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
LZS1_k127_7273619_0	1150474.JQJI01000050_gene1086	2.934e-48	174.0	COG0004@1|root,COG0004@2|Bacteria,2GD3C@200918|Thermotogae	200918|Thermotogae	P	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS1_k127_7283130_2	1054217.TALC_01360	7.061e-12	72.0	COG1304@1|root,arCOG00613@2157|Archaea,2XT6H@28890|Euryarchaeota,241IE@183967|Thermoplasmata	183967|Thermoplasmata	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
LZS1_k127_7283130_0	1054217.TALC_01359	2.233e-55	203.0	COG1608@1|root,arCOG00860@2157|Archaea,2XSUI@28890|Euryarchaeota,241QT@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS1_k127_7283130_1	673860.AciM339_0020	2.029e-20	92.0	COG1581@1|root,arCOG01753@2157|Archaea,2XZH4@28890|Euryarchaeota,3F3FZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes	albA	-	-	ko:K03622	-	-	-	-	ko00000	-	-	-	Alba
LZS1_k127_7309748_1	523850.TON_1476	2.988e-57	213.0	COG1014@1|root,arCOG01603@2157|Archaea,2XVFR@28890|Euryarchaeota,243DZ@183968|Thermococci	183968|Thermococci	C	pyruvate synthase activity	porG	-	1.2.7.1,1.2.7.7	ko:K00172,ko:K00189	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
LZS1_k127_7309748_2	406327.Mevan_0815	4.07e-20	102.0	COG1144@1|root,arCOG01605@2157|Archaea,2Y02N@28890|Euryarchaeota,23R52@183939|Methanococci	183939|Methanococci	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit	porD	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
LZS1_k127_7309748_0	391623.TERMP_01555	4.062e-70	243.0	COG0674@1|root,arCOG01608@2157|Archaea,2XTB0@28890|Euryarchaeota,24341@183968|Thermococci	183968|Thermococci	C	oxidoreductase subunit alpha	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
LZS1_k127_7321393_3	309801.trd_1743	9.615e-49	189.0	COG4927@1|root,COG4927@2|Bacteria,2GA59@200795|Chloroflexi,27ZAW@189775|Thermomicrobia	189775|Thermomicrobia	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
LZS1_k127_7321393_0	1499967.BAYZ01000028_gene1366	1.341e-123	415.0	COG3653@1|root,COG3653@2|Bacteria,2NNQ0@2323|unclassified Bacteria	2|Bacteria	Q	Amidohydrolase family	dan	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS1_k127_7321393_1	697281.Mahau_1405	1.146e-71	259.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,42F45@68295|Thermoanaerobacterales	186801|Clostridia	S	conserved protein UCP033563	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
LZS1_k127_7321393_2	1094980.Mpsy_1566	6.119e-59	215.0	COG3389@1|root,arCOG04463@2157|Archaea,2XSZT@28890|Euryarchaeota,2N9I2@224756|Methanomicrobia	224756|Methanomicrobia	S	SMART Peptidase A22, presenilin signal peptide	-	-	-	-	-	-	-	-	-	-	-	-	SPP
LZS1_k127_7321393_4	673860.AciM339_1186	1.104e-31	141.0	COG2129@1|root,arCOG01145@2157|Archaea,2XXMZ@28890|Euryarchaeota,3F2QR@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Metallophosphoesterase, calcineurin superfamily	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
LZS1_k127_7441201_6	351160.LRC332	5.879e-08	59.0	arCOG01190@1|root,arCOG01190@2157|Archaea	351160.LRC332|-	G	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7441201_2	1041930.Mtc_0083	1.548e-36	147.0	COG0619@1|root,arCOG02250@2157|Archaea,2Y0D5@28890|Euryarchaeota,2NAR1@224756|Methanomicrobia	224756|Methanomicrobia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
LZS1_k127_7441201_0	1041930.Mtc_0084	5.346e-99	340.0	COG1123@1|root,arCOG00185@2157|Archaea,2Y7PM@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC transporter	-	-	-	ko:K00400,ko:K16786,ko:K16787	ko00680,ko01100,ko01120,ko02010,map00680,map01100,map01120,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
LZS1_k127_7441201_1	351160.LRC325	4.38e-51	199.0	COG2041@1|root,arCOG00266@2157|Archaea	2157|Archaea	P	COG2041 Sulfite oxidase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	ABC_cobalt,Oxidored_molyb
LZS1_k127_7441201_7	410358.Mlab_1717	0.0001016	55.0	arCOG02547@1|root,arCOG02547@2157|Archaea	2157|Archaea	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_5
LZS1_k127_7441201_5	1297742.A176_02125	1.801e-13	83.0	COG1409@1|root,COG1409@2|Bacteria,1Q6SY@1224|Proteobacteria,433RH@68525|delta/epsilon subdivisions,2WX9D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS1_k127_7441201_3	521011.Mpal_0179	1.914e-16	94.0	COG3291@1|root,arCOG03259@2157|Archaea	2157|Archaea	M	cell wall organization	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430,NosD,Prenyltrans,S-layer
LZS1_k127_7441201_4	886293.Sinac_1058	5.197e-16	82.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_S51
LZS1_k127_7464093_0	1459636.NTE_00007	5.083e-41	164.0	COG0417@1|root,arCOG00329@2157|Archaea	2157|Archaea	L	DNA polymerase elongation subunit (Family B)	polB2	-	2.7.7.7	ko:K02319	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_pol_B
LZS1_k127_7464093_1	797114.C475_19568	8.078e-13	72.0	arCOG07300@1|root,arCOG07300@2157|Archaea,2XXYB@28890|Euryarchaeota,23WG9@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7465308_1	877455.Metbo_2057	4.1e-42	173.0	COG0842@1|root,arCOG01463@2157|Archaea,2XWB7@28890|Euryarchaeota,23PY9@183925|Methanobacteria	183925|Methanobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS1_k127_7465308_0	877455.Metbo_2056	3.642e-72	252.0	COG1131@1|root,arCOG00194@2157|Archaea,2XWVA@28890|Euryarchaeota	28890|Euryarchaeota	E	SMART ATPase, AAA type, core	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_7465308_2	1123373.ATXI01000004_gene1478	3.926e-22	104.0	COG1309@1|root,COG1309@2|Bacteria,2GHH2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS1_k127_7502407_1	439235.Dalk_1625	8.082e-98	358.0	COG0247@1|root,COG1908@1|root,COG0247@2|Bacteria,COG1908@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MIBB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9,FlpD
LZS1_k127_7502407_0	387631.Asulf_01816	0.0	1090.0	COG1148@1|root,arCOG02234@2157|Archaea,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,FlpD,Pyr_redox_2
LZS1_k127_7502407_4	429009.Adeg_2015	4.557e-51	193.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
LZS1_k127_7502407_3	523845.AQXV01000049_gene929	2.672e-82	289.0	COG2048@1|root,arCOG00338@2157|Archaea,2XTWJ@28890|Euryarchaeota,23Q3U@183939|Methanococci	183939|Methanococci	C	heterodisulfide reductase, subunit B	hdrB2	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
LZS1_k127_7502407_5	1236689.MMALV_13670	1.772e-25	114.0	COG2048@1|root,arCOG00964@2157|Archaea,2XZ7E@28890|Euryarchaeota,3F2WA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
LZS1_k127_7502407_2	647113.Metok_0186	4.806e-93	312.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
LZS1_k127_7527424_0	383372.Rcas_3603	2.83e-29	127.0	COG1100@1|root,COG1100@2|Bacteria,2G9IC@200795|Chloroflexi,3777W@32061|Chloroflexia	32061|Chloroflexia	S	SMART Ras small GTPase, Ras type	-	-	-	-	-	-	-	-	-	-	-	-	Ras
LZS1_k127_7527424_1	411466.ACTODO_02167	1.054e-15	85.0	COG0454@1|root,COG0456@2|Bacteria,2H0CI@201174|Actinobacteria,4D564@85005|Actinomycetales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS1_k127_7537793_1	1054217.TALC_00056	3.253e-78	267.0	COG1031@1|root,arCOG01359@2157|Archaea,2XSVQ@28890|Euryarchaeota	28890|Euryarchaeota	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	HHH,HHH_3,Radical_SAM
LZS1_k127_7537793_0	1236689.MMALV_00630	1.39e-78	275.0	COG2219@1|root,arCOG03013@2157|Archaea,2XTDT@28890|Euryarchaeota,3F2P0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair	priL	-	-	ko:K18882	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DNA_primase_lrg
LZS1_k127_7537793_2	1054217.TALC_00051	1.794e-54	198.0	COG0558@1|root,arCOG00670@2157|Archaea,2XWJ0@28890|Euryarchaeota,241RQ@183967|Thermoplasmata	183967|Thermoplasmata	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
LZS1_k127_7565814_0	1236689.MMALV_13780	7.798e-134	446.0	COG0277@1|root,arCOG00337@2157|Archaea,2XT5C@28890|Euryarchaeota	28890|Euryarchaeota	C	COG0277 FAD FMN-containing dehydrogenases	glcD2	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104,ko:K06911	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
LZS1_k127_7565814_1	565033.GACE_0404	4.912e-45	167.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
LZS1_k127_7582688_0	671143.DAMO_0036	5.265e-153	497.0	COG2217@1|root,COG2217@2|Bacteria,2NNPJ@2323|unclassified Bacteria	2|Bacteria	P	E1-E2 ATPase	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
LZS1_k127_7582688_1	1033810.HLPCO_000861	1.973e-38	154.0	COG0500@1|root,COG2226@2|Bacteria,2NQ2E@2323|unclassified Bacteria	2|Bacteria	Q	Methionine biosynthesis protein MetW	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS1_k127_7630389_0	1054217.TALC_00442	3.527e-155	500.0	COG0172@1|root,arCOG00403@2157|Archaea,2XTGA@28890|Euryarchaeota,241N0@183967|Thermoplasmata	183967|Thermoplasmata	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
LZS1_k127_7630389_1	368407.Memar_0764	2.496e-75	268.0	COG0475@1|root,arCOG01953@2157|Archaea,2XV77@28890|Euryarchaeota,2NATR@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
LZS1_k127_7630389_2	1236689.MMALV_03560	1.381e-57	231.0	arCOG08231@1|root,arCOG08231@2157|Archaea,2Y2GQ@28890|Euryarchaeota	28890|Euryarchaeota	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
LZS1_k127_7632179_0	1236689.MMALV_07230	7.175e-74	255.0	COG0520@1|root,arCOG00065@2157|Archaea,2XSYI@28890|Euryarchaeota	2157|Archaea	E	Cysteine desulfurase	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
LZS1_k127_7632179_2	1236689.MMALV_07250	6.733e-13	75.0	arCOG02981@1|root,arCOG02981@2157|Archaea,2Y4VF@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7632179_3	411467.BACCAP_00246	0.0003898	47.0	2DPV4@1|root,333HA@2|Bacteria,1VH7Z@1239|Firmicutes,24SC2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7632179_1	673860.AciM339_0770	2.791e-62	226.0	COG1047@1|root,arCOG00980@2157|Archaea,2XTB7@28890|Euryarchaeota,3F2P4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
LZS1_k127_7633743_0	880072.Desac_2171	2.321e-57	216.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
LZS1_k127_772721_4	439481.Aboo_1449	1.264e-65	233.0	COG2078@1|root,arCOG01336@2157|Archaea,2XUAP@28890|Euryarchaeota,3F2RN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
LZS1_k127_772721_2	1054217.TALC_01269	2.377e-108	364.0	COG0044@1|root,arCOG00689@2157|Archaea,2XTQU@28890|Euryarchaeota,241MY@183967|Thermoplasmata	183967|Thermoplasmata	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS1_k127_772721_5	1236689.MMALV_13590	3.546e-58	217.0	COG0727@1|root,arCOG02579@2157|Archaea,2Y0ZN@28890|Euryarchaeota	28890|Euryarchaeota	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
LZS1_k127_772721_6	374847.Kcr_0495	7.241e-36	143.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_IclR,TrmB
LZS1_k127_772721_8	1236689.MMALV_13580	4.504e-22	96.0	COG1958@1|root,arCOG00998@2157|Archaea,2XZTF@28890|Euryarchaeota,3F2SB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	snRNP Sm proteins	lsm	GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K04796	-	-	-	-	ko00000	-	-	-	LSM
LZS1_k127_772721_9	634498.mru_1281	1.866e-17	82.0	COG2126@1|root,arCOG04126@2157|Archaea,2XZUV@28890|Euryarchaeota,23P7A@183925|Methanobacteria	183925|Methanobacteria	J	binds to the 23S rRNA	rpl37e	-	-	ko:K02922	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L37e
LZS1_k127_772721_0	1054217.TALC_01266	5.512e-160	517.0	COG0034@1|root,arCOG00093@2157|Archaea,2XSWJ@28890|Euryarchaeota,241K9@183967|Thermoplasmata	183967|Thermoplasmata	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
LZS1_k127_772721_1	1499967.BAYZ01000006_gene5468	4.705e-111	373.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_772721_7	555088.DealDRAFT_0112	2.404e-23	104.0	2FJYI@1|root,34BKW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_772721_3	323848.Nmul_A1900	5.538e-85	289.0	COG4242@1|root,COG4242@2|Bacteria,1R5TW@1224|Proteobacteria,2VPUA@28216|Betaproteobacteria	28216|Betaproteobacteria	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
LZS1_k127_7727569_29	596327.PORUE0001_1602	6.664e-12	68.0	COG1234@1|root,COG1234@2|Bacteria,4NE1K@976|Bacteroidetes,2FM13@200643|Bacteroidia,22WDF@171551|Porphyromonadaceae	976|Bacteroidetes	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
LZS1_k127_7727569_8	1304874.JAFY01000002_gene133	1.322e-109	363.0	COG0444@1|root,COG0444@2|Bacteria,3TAUN@508458|Synergistetes	508458|Synergistetes	EP	ABC transporter	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
LZS1_k127_7727569_9	399550.Smar_1330	1.054e-108	363.0	COG4608@1|root,arCOG00184@2157|Archaea,2XPYB@28889|Crenarchaeota	28889|Crenarchaeota	E	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS1_k127_7727569_10	186497.PF1924	1.244e-105	357.0	COG3191@1|root,arCOG05721@2157|Archaea,2Y2PS@28890|Euryarchaeota,243ET@183968|Thermococci	183968|Thermococci	E	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
LZS1_k127_7727569_11	1304284.L21TH_0306	3.738e-105	355.0	COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,25CA6@186801|Clostridia,36WS4@31979|Clostridiaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS1_k127_7727569_5	688269.Theth_1319	1.416e-145	481.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS1_k127_7727569_19	456442.Mboo_2431	2.92e-47	181.0	COG0253@1|root,arCOG02255@2157|Archaea,2XUYX@28890|Euryarchaeota,2NAG6@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
LZS1_k127_7727569_6	471223.GWCH70_0291	2.648e-134	441.0	COG0001@1|root,COG0001@2|Bacteria,1TRD7@1239|Firmicutes,4HA12@91061|Bacilli,1WH7T@129337|Geobacillus	91061|Bacilli	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_7727569_13	797209.ZOD2009_15581	1.735e-87	299.0	COG2057@1|root,arCOG05316@2157|Archaea,2XW2C@28890|Euryarchaeota,23U50@183963|Halobacteria	183963|Halobacteria	I	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS1_k127_7727569_7	1227453.C444_21166	1.885e-119	391.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,23U35@183963|Halobacteria	183963|Halobacteria	I	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS1_k127_7727569_18	760568.Desku_0339	1.693e-50	182.0	COG1545@1|root,COG1545@2|Bacteria,1V5Y7@1239|Firmicutes,24IK3@186801|Clostridia,2652W@186807|Peptococcaceae	186801|Clostridia	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
LZS1_k127_7727569_15	1121430.JMLG01000002_gene1077	7.476e-76	268.0	COG3425@1|root,COG3425@2|Bacteria,1UYR0@1239|Firmicutes,24FN4@186801|Clostridia	186801|Clostridia	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
LZS1_k127_7727569_3	1121430.JMLG01000002_gene1078	7.294e-161	516.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24FFI@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS1_k127_7727569_0	1219084.AP014508_gene1722	9.224e-189	598.0	COG1509@1|root,COG1509@2|Bacteria,2GC4U@200918|Thermotogae	200918|Thermotogae	C	TIGRFAM lysine 2,3-aminomutase YodO family protein	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_14,LAM_C,Radical_SAM
LZS1_k127_7727569_2	673860.AciM339_1248	2.625e-166	531.0	COG1812@1|root,arCOG01678@2157|Archaea,2XT7J@28890|Euryarchaeota,3F2G8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the formation of S-adenosylmethionine from methionine and ATP	mat	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_Synthase
LZS1_k127_7727569_28	1343739.PAP_06665	3.59e-12	81.0	arCOG03797@1|root,arCOG03797@2157|Archaea,2Y8H2@28890|Euryarchaeota,245FQ@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF835)	-	-	-	-	-	-	-	-	-	-	-	-	DUF835
LZS1_k127_7727569_17	1047013.AQSP01000098_gene2574	1.784e-51	188.0	COG0778@1|root,COG0778@2|Bacteria,2NQ10@2323|unclassified Bacteria	2|Bacteria	C	Putative TM nitroreductase	noxC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
LZS1_k127_7727569_26	263820.PTO1201	1.23e-25	111.0	COG1522@1|root,arCOG01580@2157|Archaea,2XX5M@28890|Euryarchaeota,241X8@183967|Thermoplasmata	183967|Thermoplasmata	K	helix_turn_helix ASNC type	-	-	-	ko:K06154	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
LZS1_k127_7727569_24	768671.ThimaDRAFT_3696	4.623e-30	123.0	2E4R1@1|root,32ZJK@2|Bacteria,1N8FZ@1224|Proteobacteria,1S42H@1236|Gammaproteobacteria,1WYUX@135613|Chromatiales	135613|Chromatiales	S	Nitrous oxide-stimulated promoter	-	-	-	-	-	-	-	-	-	-	-	-	YgbA_NO
LZS1_k127_7727569_20	572547.Amico_1311	1.299e-46	185.0	COG4927@1|root,COG4927@2|Bacteria,3TB4S@508458|Synergistetes	508458|Synergistetes	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	ko:K19200	ko00311,ko01100,ko01130,map00311,map01100,map01130	-	-	-	ko00000,ko00001,ko01002	-	-	-	AAT
LZS1_k127_7727569_25	523850.TON_0889	1.249e-28	125.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y7MI@28890|Euryarchaeota,243IW@183968|Thermococci	183968|Thermococci	T	KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_7727569_23	439481.Aboo_0799	8.847e-31	134.0	COG0467@1|root,arCOG01171@2157|Archaea,2Y70F@28890|Euryarchaeota,3F32U@33867|unclassified Euryarchaeota	28890|Euryarchaeota	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
LZS1_k127_7727569_4	1236689.MMALV_07910	2.703e-159	518.0	COG0072@1|root,arCOG00412@2157|Archaea,2XTD5@28890|Euryarchaeota,3F2FI@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	B3/4 domain	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,tRNA-synt_2d
LZS1_k127_7727569_12	521011.Mpal_0170	3.609e-103	359.0	COG0642@1|root,arCOG02385@1|root,arCOG02385@2157|Archaea,arCOG06193@2157|Archaea,2Y7TZ@28890|Euryarchaeota,2NAUN@224756|Methanomicrobia	224756|Methanomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
LZS1_k127_7727569_16	673860.AciM339_0111	4.388e-66	237.0	COG1986@1|root,arCOG01221@2157|Archaea,arCOG01223@2157|Archaea,2XWGY@28890|Euryarchaeota,3F2ZA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	coaD	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K02201	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS1_k127_7727569_30	439481.Aboo_0895	1.9e-05	51.0	COG4068@1|root,arCOG04390@2157|Archaea,2Y19A@28890|Euryarchaeota,3F3EH@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Uncharacterized protein containing a Zn-ribbon (DUF2116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2116
LZS1_k127_7727569_14	439481.Aboo_1323	5.962e-80	276.0	COG1577@1|root,arCOG01028@2157|Archaea,2XSUB@28890|Euryarchaeota,3F2JQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids	mvk	GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
LZS1_k127_7727569_1	387631.Asulf_02087	4.054e-172	550.0	COG1257@1|root,arCOG04260@2157|Archaea,2XTV9@28890|Euryarchaeota,245ZK@183980|Archaeoglobi	183980|Archaeoglobi	I	Hydroxymethylglutaryl-CoA reductase, degradative	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
LZS1_k127_7727569_21	1220534.B655_1829	2.24e-33	138.0	COG0170@1|root,arCOG01880@2157|Archaea,2XY6G@28890|Euryarchaeota,23PK0@183925|Methanobacteria	183925|Methanobacteria	I	PFAM phosphatidate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7727569_22	351160.RCIX1311	8.065e-33	136.0	COG0125@1|root,arCOG01893@2157|Archaea,2XZ7Z@28890|Euryarchaeota	28890|Euryarchaeota	F	thymidylate kinase	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS1_k127_7727569_27	521011.Mpal_1954	1.982e-21	95.0	COG0053@1|root,arCOG01474@2157|Archaea,2XU96@28890|Euryarchaeota,2NAF0@224756|Methanomicrobia	224756|Methanomicrobia	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
LZS1_k127_7749318_2	269797.Mbar_A0574	3.513e-114	377.0	COG1163@1|root,arCOG00358@2157|Archaea,2XTYK@28890|Euryarchaeota,2N946@224756|Methanomicrobia	224756|Methanomicrobia	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,MMR_HSR1_Xtn,TGS
LZS1_k127_7749318_3	264732.Moth_1948	3.418e-91	311.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,42FNN@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Aspartate glutamate uridylate kinase	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS1_k127_7749318_6	1236689.MMALV_12600	0.0003111	52.0	arCOG01917@1|root,arCOG01917@2157|Archaea,2Y1TH@28890|Euryarchaeota,3F2UJ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DZR,zinc_ribbon_2
LZS1_k127_7749318_0	673860.AciM339_0322	3.69e-231	732.0	COG1389@1|root,arCOG01165@2157|Archaea,2XTZQ@28890|Euryarchaeota,3F2EU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
LZS1_k127_7749318_1	673860.AciM339_0321	3.224e-169	537.0	COG1697@1|root,arCOG04143@2157|Archaea,2XTNQ@28890|Euryarchaeota,3F2HT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
LZS1_k127_7749318_4	439481.Aboo_0164	3.039e-77	269.0	COG1578@1|root,arCOG04410@2157|Archaea,2XWGU@28890|Euryarchaeota,3F2KN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
LZS1_k127_7749318_5	1120978.KB894080_gene1202	4.643e-73	258.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,27G23@186828|Carnobacteriaceae	91061|Bacilli	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS1_k127_7871178_2	644281.MFS40622_0449	1.308e-75	260.0	COG0108@1|root,arCOG01320@2157|Archaea,2XTDZ@28890|Euryarchaeota,23Q9J@183939|Methanococci	183939|Methanococci	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.12	ko:K02858	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R07281	RC01792,RC01815	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase
LZS1_k127_7871178_7	673860.AciM339_0317	2.5e-45	168.0	COG0615@1|root,arCOG01222@2157|Archaea,2XX70@28890|Euryarchaeota,3F2RF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme	ribL	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.7.2	ko:K14656	ko00740,ko01100,ko01110,map00740,map01100,map01110	-	R00161	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
LZS1_k127_7871178_3	439481.Aboo_0746	4.278e-65	238.0	COG1731@1|root,arCOG01322@2157|Archaea,2XX0K@28890|Euryarchaeota,3F2K2@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	6,7-dimethyl-8-ribityllumazine synthase	ribC	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
LZS1_k127_7871178_6	1236689.MMALV_10210	6.478e-46	175.0	COG0054@1|root,arCOG01323@2157|Archaea,2XXXC@28890|Euryarchaeota,3F2P5@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
LZS1_k127_7871178_0	1236689.MMALV_10340	3.75e-177	576.0	COG0175@1|root,arCOG00073@2157|Archaea,2XUPU@28890|Euryarchaeota,3F2GA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A0559	Fer4,Fer4_10,Fer4_7,PAPS_reduct,PUA
LZS1_k127_7871178_4	1236689.MMALV_07190	4.026e-58	212.0	arCOG04973@1|root,arCOG04973@2157|Archaea,2XX73@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7871178_8	1235279.C772_02289	1.352e-38	151.0	COG1670@1|root,COG1670@2|Bacteria,1V40F@1239|Firmicutes,4HGKM@91061|Bacilli,26F35@186818|Planococcaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
LZS1_k127_7871178_1	1236689.MMALV_05020	4.916e-115	381.0	COG0505@1|root,arCOG00064@2157|Archaea,2XT0H@28890|Euryarchaeota	28890|Euryarchaeota	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
LZS1_k127_7871178_5	1236689.MMALV_05010	3.762e-46	169.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2374	CPSase_L_D2,CPSase_L_D3,MGS
LZS1_k127_7897062_7	1121468.AUBR01000018_gene2711	4.266e-15	77.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia	186801|Clostridia	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS1_k127_7897062_3	693661.Arcve_0149	1.353e-35	142.0	COG3398@1|root,arCOG02611@2157|Archaea,2XWAQ@28890|Euryarchaeota,246Q2@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
LZS1_k127_7897062_2	118163.Ple7327_3118	1.837e-57	216.0	COG0520@1|root,COG0520@2|Bacteria,1G4XH@1117|Cyanobacteria,3VHS8@52604|Pleurocapsales	1117|Cyanobacteria	E	Cysteine desulfurase family protein, VC1184 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS1_k127_7897062_5	439481.Aboo_0593	3.324e-23	114.0	arCOG13530@1|root,arCOG13530@2157|Archaea,2Y727@28890|Euryarchaeota,3F38E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7897062_6	593117.TGAM_2006	1.189e-20	108.0	COG1672@1|root,arCOG03042@1|root,arCOG03042@2157|Archaea,arCOG03169@2157|Archaea,2Y7QE@28890|Euryarchaeota,245KV@183968|Thermococci	183968|Thermococci	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7897062_1	304371.MCP_1481	1.195e-96	324.0	28M2T@1|root,2N55N@2157|Archaea,2Y31V@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7897062_0	304371.MCP_1482	2.31e-305	960.0	COG0574@1|root,arCOG01114@2157|Archaea,2XVSY@28890|Euryarchaeota	28890|Euryarchaeota	G	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
LZS1_k127_7897062_9	232348.ADXL01000058_gene2393	2.139e-05	53.0	COG0517@1|root,COG0517@2|Bacteria,1G5TQ@1117|Cyanobacteria,1H08Q@1129|Synechococcus	1117|Cyanobacteria	S	CBS domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
LZS1_k127_7897062_4	593750.Metfor_1644	8.538e-34	148.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUW2@28890|Euryarchaeota,2N9TY@224756|Methanomicrobia	224756|Methanomicrobia	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
LZS1_k127_7897062_8	1122609.AUGT01000013_gene4105	6.025e-08	58.0	COG2909@1|root,COG2909@2|Bacteria,2I50W@201174|Actinobacteria,4DPMG@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
LZS1_k127_7915640_0	673860.AciM339_0643	1.016e-103	345.0	COG0464@1|root,arCOG01308@2157|Archaea,2XSYR@28890|Euryarchaeota,3F39E@33867|unclassified Euryarchaeota	28890|Euryarchaeota	O	Cell division protein 48 (CDC48), domain 2	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
LZS1_k127_7915640_1	189753.AXAS01000001_gene3837	4.75e-23	105.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,3JYE3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Hsp20/alpha crystallin family	hspC2	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS1_k127_7915640_2	351160.RRC215	5.165e-20	96.0	COG1676@1|root,arCOG01701@2157|Archaea,2XTKB@28890|Euryarchaeota,2N92W@224756|Methanomicrobia	224756|Methanomicrobia	J	sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp	endA	-	4.6.1.16	ko:K01170	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_int_endo,tRNA_int_endo_N
LZS1_k127_7940518_1	1094980.Mpsy_2804	2.605e-75	266.0	COG1234@1|root,arCOG00501@2157|Archaea,2XTJ9@28890|Euryarchaeota,2N96S@224756|Methanomicrobia	224756|Methanomicrobia	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
LZS1_k127_7940518_4	673860.AciM339_0586	3.081e-54	206.0	COG0477@1|root,arCOG00130@2157|Archaea,2Y726@28890|Euryarchaeota,3F38D@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K19576	-	-	-	-	ko00000,ko02000	2.A.1.2.10	-	-	MFS_1
LZS1_k127_7940518_5	673860.AciM339_0275	3.697e-12	68.0	arCOG05330@1|root,arCOG05330@2157|Archaea,2Y24Y@28890|Euryarchaeota,3F3GX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7940518_2	1461580.CCAS010000004_gene592	9.652e-60	214.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
LZS1_k127_7940518_0	673860.AciM339_0552	4.641e-106	354.0	COG0258@1|root,arCOG04050@2157|Archaea,2XTJD@28890|Euryarchaeota,3F2GZ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA	fen	-	-	ko:K04799	ko03030,ko03410,ko03450,map03030,map03410,map03450	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400,ko04147	-	-	-	XPG_I,XPG_N
LZS1_k127_7940518_3	572546.Arcpr_0361	1.281e-59	210.0	COG0060@1|root,arCOG00807@2157|Archaea,2XTIX@28890|Euryarchaeota,2462I@183980|Archaeoglobi	183980|Archaeoglobi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
LZS1_k127_7948987_9	673860.AciM339_0504	0.0001894	49.0	COG3430@1|root,arCOG02423@2157|Archaea	2157|Archaea	S	Pfam:DUF1628	-	-	-	-	-	-	-	-	-	-	-	-	Pilin_N
LZS1_k127_7948987_8	868131.MSWAN_0477	4.963e-07	58.0	COG1714@1|root,arCOG03633@2157|Archaea,2Y140@28890|Euryarchaeota,23P6J@183925|Methanobacteria	183925|Methanobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
LZS1_k127_7948987_4	868131.MSWAN_0374	5.655e-44	169.0	COG2042@1|root,arCOG04733@2157|Archaea,2XVBD@28890|Euryarchaeota,23P0G@183925|Methanobacteria	183925|Methanobacteria	J	pre-rRNA processing protein involved in ribosome biogenesis	-	-	-	ko:K09140	-	-	-	-	ko00000,ko03009	-	-	-	RLI,Ribo_biogen_C
LZS1_k127_7948987_1	1236689.MMALV_16800	1.467e-212	681.0	COG1241@1|root,arCOG00439@2157|Archaea,2XT5D@28890|Euryarchaeota,3F2HN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	MCM OB domain	mcm	-	-	ko:K10726	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	HTH_3,Intein_splicing,LAGLIDADG_3,MCM,MCM_N,MCM_OB
LZS1_k127_7948987_6	1042877.GQS_04315	2.832e-25	108.0	COG2412@1|root,arCOG04051@2157|Archaea,2XYQK@28890|Euryarchaeota,244B2@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF424)	-	-	-	ko:K09148	-	-	-	-	ko00000	-	-	-	DUF424
LZS1_k127_7948987_5	673860.AciM339_1476	7.858e-38	155.0	COG1499@1|root,arCOG04149@2157|Archaea,2XUAI@28890|Euryarchaeota,3F2MW@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	NMD3 family	nmd3	-	-	ko:K07562	ko03008,ko03013,map03008,map03013	-	-	-	ko00000,ko00001,ko03009	-	-	-	NMD3
LZS1_k127_7948987_2	351160.RCIX2057	8.23e-95	319.0	COG1951@1|root,arCOG04407@2157|Archaea,2XUQI@28890|Euryarchaeota,2N9FT@224756|Methanomicrobia	224756|Methanomicrobia	C	Fe-S type, tartrate fumarate subfamily, alpha	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
LZS1_k127_7948987_3	374847.Kcr_0094	2.25e-63	223.0	COG1838@1|root,arCOG04406@2157|Archaea	2157|Archaea	C	Fe-S type, tartrate fumarate subfamily, beta	fumB	-	4.2.1.2,4.2.1.32	ko:K01676,ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
LZS1_k127_7948987_7	1283287.KB822582_gene2878	8.056e-11	75.0	COG4932@1|root,COG4932@2|Bacteria,2HFQZ@201174|Actinobacteria,4DW2Q@85009|Propionibacteriales	2|Bacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,RCC1_2
LZS1_k127_7948987_0	1236689.MMALV_16740	0.0	1492.0	COG1201@1|root,arCOG00557@2157|Archaea,2XSTH@28890|Euryarchaeota,3F2IQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DEAD/H associated	lhr2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
LZS1_k127_7949526_0	1236689.MMALV_05010	7.235e-303	942.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2374	CPSase_L_D2,CPSase_L_D3,MGS
LZS1_k127_7966066_3	224325.AF_1111	6.772e-06	52.0	COG4004@1|root,arCOG04412@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7966066_2	1001530.BACE01000026_gene1351	3.34e-31	138.0	COG1075@1|root,COG2304@1|root,COG5183@1|root,COG1075@2|Bacteria,COG2304@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,1XVD5@135623|Vibrionales	135623|Vibrionales	A	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,TSP_3
LZS1_k127_7966066_1	673860.AciM339_0248	8.306e-83	286.0	COG1244@1|root,arCOG01360@2157|Archaea,2XT5Q@28890|Euryarchaeota,3F2I0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	Radical_SAM
LZS1_k127_7966066_0	1054217.TALC_00320	1.566e-91	307.0	COG0162@1|root,arCOG01886@2157|Archaea,2XTA0@28890|Euryarchaeota,241NP@183967|Thermoplasmata	183967|Thermoplasmata	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
LZS1_k127_8010491_2	459349.CLOAM0398	2.629e-08	66.0	COG2931@1|root,COG2931@2|Bacteria,2NQ7A@2323|unclassified Bacteria	2|Bacteria	Q	Clostripain family	rtxA	GO:0000166,GO:0000287,GO:0000822,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005576,GO:0006464,GO:0006508,GO:0006807,GO:0006996,GO:0007010,GO:0007015,GO:0008144,GO:0008150,GO:0008152,GO:0008154,GO:0008233,GO:0008234,GO:0009405,GO:0009987,GO:0010467,GO:0016043,GO:0016485,GO:0016540,GO:0016787,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018149,GO:0018153,GO:0018193,GO:0018199,GO:0018205,GO:0018262,GO:0018995,GO:0019538,GO:0019835,GO:0019836,GO:0020002,GO:0022411,GO:0030029,GO:0030036,GO:0030042,GO:0030554,GO:0031640,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033643,GO:0033644,GO:0035639,GO:0035821,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043178,GO:0043412,GO:0043624,GO:0043657,GO:0043933,GO:0044003,GO:0044004,GO:0044179,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044279,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046872,GO:0051261,GO:0051604,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0097435,GO:0140096,GO:1901265,GO:1901363,GO:1901564	-	ko:K10953	ko05110,map05110	-	-	-	ko00000,ko00001,ko02042	-	-	-	ACD,Calx-beta,DUF4347,He_PIG,Hydrolase_4,Laminin_G_3,MLD,Peptidase_C11,Peptidase_C58,Peptidase_C80,RtxA
LZS1_k127_8010491_4	269797.Mbar_A1819	1.395e-06	58.0	COG2512@1|root,arCOG00386@2157|Archaea	2157|Archaea	S	membrane-associated protein domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR,MarR_2,TrmB
LZS1_k127_8010491_5	1265503.KB905164_gene1873	8.291e-06	56.0	COG3209@1|root,COG3637@1|root,COG5183@1|root,COG3209@2|Bacteria,COG3637@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,2Q7I7@267889|Colwelliaceae	1236|Gammaproteobacteria	A	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
LZS1_k127_8010491_3	1278307.KB906967_gene2496	3.971e-07	64.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_8010491_1	1396141.BATP01000016_gene2780	5.279e-13	83.0	COG1075@1|root,COG4099@1|root,COG4625@1|root,COG1075@2|Bacteria,COG4099@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.5.4.40	ko:K18286,ko:K20276	ko00130,ko01110,ko02024,map00130,map01110,map02024	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_8,Big_5,SLH,SWM_repeat
LZS1_k127_8010491_0	439481.Aboo_0134	9.322e-83	306.0	COG4870@1|root,arCOG02499@1|root,arCOG05978@1|root,arCOG02499@2157|Archaea,arCOG03607@2157|Archaea,arCOG05978@2157|Archaea	2157|Archaea	C	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_5,Kelch_1,NosD,Peptidase_C1,S_layer_C,fn3
LZS1_k127_8117787_2	1449044.JMLE01000028_gene261	7.154e-11	69.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_3,Flavodoxin_5
LZS1_k127_8117787_1	1236689.MMALV_00680	8.188e-19	86.0	COG2888@1|root,arCOG01989@2157|Archaea,2Y6XW@28890|Euryarchaeota,3F2UA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Domain of unknown function (DUF1610)	-	-	-	ko:K07580	-	-	-	-	ko00000	-	-	-	DUF1610
LZS1_k127_8117787_3	384616.Pisl_0684	1.142e-05	51.0	COG2092@1|root,arCOG01988@2157|Archaea,2XR49@28889|Crenarchaeota	28889|Crenarchaeota	J	Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA	ef1b	-	-	ko:K03232	-	-	-	-	ko00000,ko03012	-	-	-	EF1_GNE
LZS1_k127_8117787_0	1047013.AQSP01000073_gene1101	8.334e-56	198.0	COG0281@1|root,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria	2|Bacteria	C	Malic enzyme, NAD binding domain	mez_1	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
LZS1_k127_83456_1	1265505.ATUG01000001_gene4313	7.111e-21	101.0	COG5598@1|root,COG5598@2|Bacteria,1N18H@1224|Proteobacteria,43BDY@68525|delta/epsilon subdivisions,2X6SF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
LZS1_k127_83456_0	1089553.Tph_c27670	4.664e-56	202.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548,ko:K14084	ko00270,ko00450,ko00670,ko00680,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map01100,map01110,map01120,map01200,map01230	M00017,M00563	R00946,R09124,R09365	RC00035,RC00113,RC00732,RC01241,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
LZS1_k127_849779_2	647113.Metok_0596	4.758e-08	60.0	COG1047@1|root,arCOG00981@2157|Archaea,2XXFW@28890|Euryarchaeota,23RME@183939|Methanococci	183939|Methanococci	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
LZS1_k127_849779_1	673860.AciM339_1499	1.938e-13	73.0	COG1977@1|root,arCOG00536@2157|Archaea,2Y6GJ@28890|Euryarchaeota,3F3IT@33867|unclassified Euryarchaeota	28890|Euryarchaeota	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS1_k127_849779_0	1196323.ALKF01000197_gene2310	1.64e-84	292.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,26TJQ@186822|Paenibacillaceae	91061|Bacilli	P	ATPase P	copA	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS1_k127_863657_0	1236689.MMALV_05010	0.0	1257.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the CarB family	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2374	CPSase_L_D2,CPSase_L_D3,MGS
LZS1_k127_87494_0	273075.Ta0519	1.68e-79	274.0	COG0017@1|root,arCOG00407@2157|Archaea,2XTZJ@28890|Euryarchaeota,241ZH@183967|Thermoplasmata	183967|Thermoplasmata	J	asparaginyl-tRNA aminoacylation	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS1_k127_87494_2	1122931.AUAE01000030_gene841	3.865e-10	71.0	COG0454@1|root,COG0456@2|Bacteria,4NVA5@976|Bacteroidetes,2FT3B@200643|Bacteroidia	976|Bacteroidetes	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS1_k127_87494_1	673860.AciM339_0894	1.426e-33	138.0	COG0060@1|root,arCOG00807@2157|Archaea,2XTIX@28890|Euryarchaeota,3F2FG@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
LZS1_k127_92579_2	351160.RCIX2032	3.191e-90	299.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,2N97D@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS1_k127_92579_3	1094980.Mpsy_2508	2.934e-74	255.0	COG1394@1|root,arCOG04101@2157|Archaea,2XTQ5@28890|Euryarchaeota,2N9IG@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	iAF692.Mbar_A0384	ATP-synt_D
LZS1_k127_92579_1	1128421.JAGA01000002_gene371	3.582e-110	373.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria	2|Bacteria	C	synthetase (ADP forming), alpha	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
LZS1_k127_92579_0	1236689.MMALV_00150	5.956e-134	443.0	COG1311@1|root,arCOG04455@2157|Archaea,2XSUG@28890|Euryarchaeota,3F2GQ@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase	polB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02323	ko00230,ko00240,ko01100,ko03030,map00230,map00240,map01100,map03030	M00264	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	DNA_pol_E_B,Metallophos
LZS1_k127_9371_5	1131269.AQVV01000039_gene1537	6.039e-31	125.0	COG0294@1|root,COG0294@2|Bacteria	2|Bacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
LZS1_k127_9371_2	351160.RCIX2	1.062e-38	165.0	COG2202@1|root,arCOG02353@1|root,arCOG02353@2157|Archaea,arCOG06515@2157|Archaea,2Y3CS@28890|Euryarchaeota,2NAS5@224756|Methanomicrobia	224756|Methanomicrobia	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_9371_6	1236689.MMALV_14760	1.27e-23	102.0	COG1644@1|root,arCOG04244@2157|Archaea,2Y03I@28890|Euryarchaeota,3F2UX@33867|unclassified Euryarchaeota	28890|Euryarchaeota	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoN	GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03058	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00184	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	RNA_pol_N
LZS1_k127_9371_1	439481.Aboo_1476	1.125e-45	175.0	COG0088@1|root,arCOG04243@2157|Archaea,2XWK0@28890|Euryarchaeota,3F2N4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the universal ribosomal protein uS9 family	rps9	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS1_k127_9371_3	323259.Mhun_2897	1.353e-37	145.0	COG0102@1|root,arCOG04242@2157|Archaea,2XWN6@28890|Euryarchaeota,2N9Q5@224756|Methanomicrobia	224756|Methanomicrobia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rpl13	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
LZS1_k127_9371_4	673860.AciM339_1030	2.004e-32	132.0	COG1727@1|root,arCOG00780@2157|Archaea,2XZ6R@28890|Euryarchaeota,3F2U4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Belongs to the eukaryotic ribosomal protein eL18 family	rpl18e	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02883	ko03010,map03010	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18,Ribosomal_L27A
LZS1_k127_9371_0	439481.Aboo_0637	1.67e-75	262.0	COG0648@1|root,arCOG01894@2157|Archaea,2XU62@28890|Euryarchaeota,3F2J1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
LZS1_k127_99210_1	877455.Metbo_0099	1.243e-47	181.0	COG1968@1|root,arCOG04761@2157|Archaea,2XTYX@28890|Euryarchaeota,23NY7@183925|Methanobacteria	183925|Methanobacteria	I	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
LZS1_k127_99210_0	589924.Ferp_0234	4.382e-63	246.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,2478R@183980|Archaeoglobi	28890|Euryarchaeota	O	Peptidase S8 and S53 subtilisin kexin sedolisin	-	-	3.4.21.62	ko:K01342,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
## 1669 queries scanned
## Total time (seconds): 71.57502865791321
## Rate: 23.32 q/s