## Thu Oct 17 08:38:34 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/LZS1_bin.149.fa -m mmseqs --itype genome -o LZS1_bin.149 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/LZS1_bin.149 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
LZS1_k127_1004370_0	671143.DAMO_1059	7.391e-68	250.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
LZS1_k127_1004370_1	1144275.COCOR_06454	2.042e-40	158.0	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,43BK7@68525|delta/epsilon subdivisions,2X5W4@28221|Deltaproteobacteria,2Z37Z@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS1_k127_1016094_4	234267.Acid_7180	2.283e-30	128.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria	57723|Acidobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
LZS1_k127_1016094_0	395495.Lcho_1343	4.833e-298	934.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,1KN24@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS1_k127_1016094_8	591023.AM202_0223	2.733e-08	68.0	COG3043@1|root,COG3043@2|Bacteria,1RHGD@1224|Proteobacteria,1S7AH@1236|Gammaproteobacteria,1YAQZ@135625|Pasteurellales	135625|Pasteurellales	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	-	-	-	-	-	-	-	-	-	-	-	-	NapB
LZS1_k127_1016094_5	404589.Anae109_0411	1.257e-29	133.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS1_k127_1016094_7	1122194.AUHU01000006_gene588	3.458e-14	83.0	COG0517@1|root,COG0517@2|Bacteria,1N8E9@1224|Proteobacteria,1SC9B@1236|Gammaproteobacteria,467S1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS1_k127_1016094_3	290397.Adeh_0837	3.087e-37	148.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1016094_1	767029.HMPREF9154_2111	1.185e-101	343.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS1_k127_1016094_2	937777.Deipe_2450	2.468e-64	233.0	COG0373@1|root,COG0373@2|Bacteria,1WIN9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS1_k127_1016094_6	1201288.M900_1265	4.106e-21	105.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2MT5W@213481|Bdellovibrionales,2WMWV@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS1_k127_1023867_1	414684.RC1_1562	3.586e-46	182.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2JPW9@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
LZS1_k127_1023867_2	483219.LILAB_20900	2.911e-24	115.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2YVM8@29|Myxococcales	28221|Deltaproteobacteria	O	peptidylprolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS1_k127_1023867_3	706587.Desti_1469	7.194e-17	91.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2MRZD@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS1_k127_1023867_0	644966.Tmar_0100	1.298e-186	606.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WCCX@538999|Clostridiales incertae sedis	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
LZS1_k127_1030983_2	1184267.A11Q_1099	8.987e-36	143.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2MSMR@213481|Bdellovibrionales,2WIY6@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
LZS1_k127_1030983_1	1500301.JQMF01000004_gene3449	9.146e-63	228.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,4B7SN@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Aldo keto reductase	mocA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0017144,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS1_k127_1030983_0	690850.Desaf_0829	6.87e-85	306.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2M927@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS1_k127_1039378_2	756067.MicvaDRAFT_4353	1.138e-18	93.0	COG2114@1|root,COG2114@2|Bacteria,1G6D6@1117|Cyanobacteria,1HB2S@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
LZS1_k127_1039378_4	1380394.JADL01000001_gene2507	5.893e-07	59.0	2EJPN@1|root,33DEG@2|Bacteria,1NJ0G@1224|Proteobacteria,2UKKF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1039378_0	1192034.CAP_5737	1.717e-94	316.0	COG1398@1|root,COG1398@2|Bacteria,1Q353@1224|Proteobacteria,43069@68525|delta/epsilon subdivisions,2WVDR@28221|Deltaproteobacteria,2YXY2@29|Myxococcales	28221|Deltaproteobacteria	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS1_k127_1039378_3	1089545.KB913037_gene1197	1.123e-07	62.0	COG0500@1|root,COG2226@2|Bacteria,2IM1I@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
LZS1_k127_1039378_1	439235.Dalk_2218	5.774e-33	139.0	COG1216@1|root,COG1216@2|Bacteria,1QW1K@1224|Proteobacteria,43BRI@68525|delta/epsilon subdivisions,2WN0V@28221|Deltaproteobacteria,2MM2M@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_1045846_3	314345.SPV1_03118	1.055e-07	62.0	COG1538@1|root,COG1538@2|Bacteria,1R4EG@1224|Proteobacteria	1224|Proteobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS1_k127_1045846_1	639030.JHVA01000001_gene1094	1.17e-37	149.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS1_k127_1045846_2	1144275.COCOR_04423	7.797e-09	68.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DUF4096
LZS1_k127_1045846_0	999541.bgla_2g01540	1.029e-38	153.0	COG2120@1|root,COG2120@2|Bacteria,1NUQU@1224|Proteobacteria,2W27T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS1_k127_1055518_3	1896.JOAU01000024_gene3582	0.000533	54.0	COG4733@1|root,COG4733@2|Bacteria,2GNV7@201174|Actinobacteria	201174|Actinobacteria	E	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
LZS1_k127_1055518_1	35754.JNYJ01000020_gene252	8.578e-06	60.0	COG2133@1|root,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4DC41@85008|Micromonosporales	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,F5_F8_type_C,GSDH,RicinB_lectin_2,Ricin_B_lectin,fn3
LZS1_k127_1055518_2	491205.JARQ01000002_gene298	1.959e-05	59.0	COG3291@1|root,COG3291@2|Bacteria,4NDZQ@976|Bacteroidetes,1HX5A@117743|Flavobacteriia,3ZQTK@59732|Chryseobacterium	976|Bacteroidetes	S	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,IgGFc_binding,SprB
LZS1_k127_1055518_0	1120985.AUMI01000011_gene397	1.135e-10	74.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Phenol_MetA_deg
LZS1_k127_105989_2	1121405.dsmv_2333	4.483e-24	108.0	COG3807@1|root,COG3807@2|Bacteria,1RIYJ@1224|Proteobacteria,42SNK@68525|delta/epsilon subdivisions,2WPNS@28221|Deltaproteobacteria,2MK8E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
LZS1_k127_105989_3	290315.Clim_2345	4.189e-17	87.0	COG2905@1|root,COG2905@2|Bacteria,1FDZW@1090|Chlorobi	1090|Chlorobi	T	signal-transduction protein with CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS1_k127_105989_1	1123371.ATXH01000009_gene1077	2.538e-135	439.0	COG0438@1|root,COG0438@2|Bacteria,2GHNP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS1_k127_105989_0	330214.NIDE3191	2.007e-253	801.0	COG3408@1|root,COG3408@2|Bacteria,3J0Z8@40117|Nitrospirae	40117|Nitrospirae	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
LZS1_k127_105989_4	1047013.AQSP01000073_gene1092	8.475e-12	77.0	COG1305@1|root,COG3391@1|root,COG1305@2|Bacteria,COG3391@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Transglut_core
LZS1_k127_105989_6	1547437.LL06_10255	0.0002036	53.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2TTUP@28211|Alphaproteobacteria,43IJ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	F	Belongs to the 5'-nucleotidase family	MA20_07595	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos
LZS1_k127_105989_7	653733.Selin_1273	0.0008226	51.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
LZS1_k127_105989_5	1121904.ARBP01000052_gene3650	5.045e-08	64.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Hydrolase_4
LZS1_k127_1097182_1	247490.KSU1_D0830	9.376e-169	552.0	COG0046@1|root,COG0046@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
LZS1_k127_1097182_10	1125863.JAFN01000001_gene308	1.438e-08	63.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
LZS1_k127_1097182_4	479434.Sthe_1292	2.271e-100	338.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia	189775|Thermomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
LZS1_k127_1097182_0	290397.Adeh_2348	4.518e-194	635.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2YTZV@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
LZS1_k127_1097182_2	1156937.MFUM_1020090	6.365e-165	527.0	COG0516@1|root,COG0516@2|Bacteria,46W51@74201|Verrucomicrobia,37FWR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	IMP dehydrogenase / GMP reductase domain	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
LZS1_k127_1097182_7	1312959.KI914621_gene2419	7.071e-18	87.0	COG0745@1|root,COG0745@2|Bacteria,2IQWH@201174|Actinobacteria,1WA4T@1268|Micrococcaceae	201174|Actinobacteria	T	cheY-homologous receiver domain	ompR	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_1097182_8	177437.HRM2_02420	3.016e-14	79.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_1097182_5	1385517.N800_01695	5.614e-56	218.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1X3H4@135614|Xanthomonadales	135614|Xanthomonadales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
LZS1_k127_1097182_6	667014.Thein_1119	2.89e-28	118.0	2A6WD@1|root,30VR5@2|Bacteria,2GIJI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Domain of unknown function (DUF4234)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234
LZS1_k127_1097182_9	1112204.GPOL_c13690	7.979e-09	64.0	2EGD2@1|root,33A4V@2|Bacteria,2GWY9@201174|Actinobacteria,4GECV@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
LZS1_k127_1097182_3	575540.Isop_2455	2.844e-113	384.0	COG1961@1|root,COG1961@2|Bacteria,2IYJH@203682|Planctomycetes	203682|Planctomycetes	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS1_k127_1097359_1	1380355.JNIJ01000045_gene5490	1.063e-12	82.0	2E328@1|root,32Y2G@2|Bacteria,1N9RI@1224|Proteobacteria,2UFJ4@28211|Alphaproteobacteria,3K0VA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1097359_0	880072.Desac_2171	2.222e-138	467.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
LZS1_k127_1097359_2	797114.C475_19568	1.271e-05	50.0	arCOG07300@1|root,arCOG07300@2157|Archaea,2XXYB@28890|Euryarchaeota,23WG9@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1102654_1	1455608.JDTH01000002_gene441	6.617e-181	587.0	COG4799@1|root,arCOG02705@2157|Archaea,2XSVM@28890|Euryarchaeota,23T6H@183963|Halobacteria	183963|Halobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB2	GO:0003674,GO:0003824,GO:0004658,GO:0016421,GO:0016874,GO:0016885	2.1.3.15,6.4.1.2,6.4.1.3	ko:K19312	ko00280,ko00630,ko00640,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01120,map01130,map01200	M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS1_k127_1102654_6	526227.Mesil_0680	4.458e-27	125.0	COG0346@1|root,COG0346@2|Bacteria,1WJZW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
LZS1_k127_1102654_3	529709.PYCH_16980	5.096e-71	251.0	COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,242YC@183968|Thermococci	183968|Thermococci	E	GTPase activity	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
LZS1_k127_1102654_4	370438.PTH_1362	1.027e-52	192.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,261QG@186807|Peptococcaceae	186801|Clostridia	I	methylmalonyl-CoA mutase C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
LZS1_k127_1102654_5	289376.THEYE_A2006	1.788e-49	202.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,3J18S@40117|Nitrospirae	40117|Nitrospirae	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1102654_2	760142.Hipma_0476	8.024e-125	423.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
LZS1_k127_1102654_0	981383.AEWH01000003_gene1503	1.598e-186	599.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS1_k127_1102654_7	862908.BMS_3228	9.366e-07	51.0	COG1430@1|root,COG1430@2|Bacteria,1N7U4@1224|Proteobacteria,42VKG@68525|delta/epsilon subdivisions,2MT6V@213481|Bdellovibrionales,2WSD0@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
LZS1_k127_1108526_4	679926.Mpet_1167	1.005e-11	70.0	COG1598@1|root,arCOG02411@2157|Archaea,2Y1KD@28890|Euryarchaeota,2NB9U@224756|Methanomicrobia	224756|Methanomicrobia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
LZS1_k127_1108526_5	667014.Thein_0703	5.178e-10	66.0	COG1724@1|root,COG1724@2|Bacteria,2GIPV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
LZS1_k127_1108526_0	502025.Hoch_2046	1.72e-81	286.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2Z35Q@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS1_k127_1108526_6	187272.Mlg_1872	8.759e-07	59.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS1_k127_1108526_2	1231190.NA8A_03545	1.44e-31	139.0	COG2199@1|root,COG3437@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,43IGX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
LZS1_k127_1108526_3	1380390.JIAT01000009_gene2013	2.881e-30	134.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GISS@201174|Actinobacteria,4CPN9@84995|Rubrobacteria	84995|Rubrobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS1_k127_1108526_1	926561.KB900623_gene720	1.227e-31	131.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3WAQE@53433|Halanaerobiales	186801|Clostridia	L	PFAM Conserved	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
LZS1_k127_1111225_3	247490.KSU1_C0739	6.609e-08	57.0	COG1074@1|root,COG1074@2|Bacteria,2IX2I@203682|Planctomycetes	203682|Planctomycetes	L	UvrD REP helicase	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS1_k127_1111225_4	1236973.JCM9157_3790	0.0001016	55.0	COG1266@1|root,COG1266@2|Bacteria,1UZGJ@1239|Firmicutes,4HFCB@91061|Bacilli,1ZBE1@1386|Bacillus	91061|Bacilli	S	CAAX protease self-immunity	ydiL	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS1_k127_1111225_2	1123277.KB893239_gene1117	7.362e-12	75.0	2D6MI@1|root,32TMJ@2|Bacteria,4NPMS@976|Bacteroidetes,47Q9V@768503|Cytophagia	976|Bacteroidetes	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
LZS1_k127_1111225_1	411470.RUMGNA_01790	1.454e-30	127.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3Y0DK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
LZS1_k127_1111225_0	314345.SPV1_00095	2.433e-159	541.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS1_k127_1123517_0	1278073.MYSTI_05699	2.34e-107	369.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS1_k127_1123517_3	631362.Thi970DRAFT_02025	6.455e-15	79.0	COG3437@1|root,COG5001@1|root,COG3437@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1T4WK@1236|Gammaproteobacteria,1WZZ2@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,Response_reg
LZS1_k127_1123517_1	379731.PST_2043	4.376e-19	95.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,1SBRX@1236|Gammaproteobacteria,1Z16X@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	CmpX protein	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
LZS1_k127_1123517_5	573413.Spirs_2360	4.28e-05	56.0	COG4254@1|root,COG4254@2|Bacteria,2J9KS@203691|Spirochaetes	203691|Spirochaetes	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
LZS1_k127_1123517_2	402777.KB235904_gene2751	6.384e-18	89.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1G2P9@1117|Cyanobacteria,1H843@1150|Oscillatoriales	1117|Cyanobacteria	MT	PFAM Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
LZS1_k127_1123517_4	459495.SPLC1_S490170	9.039e-08	68.0	COG0265@1|root,COG0265@2|Bacteria,1G0XN@1117|Cyanobacteria,1H8PC@1150|Oscillatoriales	1117|Cyanobacteria	O	COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PPC,Trypsin_2
LZS1_k127_1132385_0	555778.Hneap_1456	2.041e-29	137.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,1WWRR@135613|Chromatiales	135613|Chromatiales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
LZS1_k127_1133398_4	439235.Dalk_2218	1.305e-16	86.0	COG1216@1|root,COG1216@2|Bacteria,1QW1K@1224|Proteobacteria,43BRI@68525|delta/epsilon subdivisions,2WN0V@28221|Deltaproteobacteria,2MM2M@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_1133398_1	439235.Dalk_1372	1.997e-44	181.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MN52@213118|Desulfobacterales	28221|Deltaproteobacteria	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
LZS1_k127_1133398_5	1097668.BYI23_B007990	2.01e-05	55.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria,1K0WR@119060|Burkholderiaceae	28216|Betaproteobacteria	M	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_1133398_3	751994.AGIG01000017_gene87	5.238e-31	138.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,HemolysinCabind
LZS1_k127_1133398_2	1177928.TH2_16351	3.124e-41	169.0	COG0457@1|root,COG0457@2|Bacteria,1N1I4@1224|Proteobacteria,2V9ES@28211|Alphaproteobacteria,2JTPA@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_19
LZS1_k127_1133398_0	1286171.EAL2_808p03370	3.808e-65	237.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,25ZF5@186806|Eubacteriaceae	186801|Clostridia	O	Subtilase family	isp	-	3.4.21.62	ko:K01342,ko:K13275	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
LZS1_k127_1145490_1	556268.OFAG_00881	4.248e-47	177.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2VTR4@28216|Betaproteobacteria,478T4@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
LZS1_k127_1145490_0	439235.Dalk_4346	3.196e-160	520.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MIA8@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS1_k127_1145490_2	204669.Acid345_3128	1.513e-09	64.0	COG1287@1|root,COG1287@2|Bacteria,3Y5FJ@57723|Acidobacteria,2JJV3@204432|Acidobacteriia	204432|Acidobacteriia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1155021_1	1403819.BATR01000133_gene4729	6.227e-138	446.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
LZS1_k127_1155021_23	656519.Halsa_1893	1.726e-28	117.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3WAUY@53433|Halanaerobiales	186801|Clostridia	J	TIGRFAM ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
LZS1_k127_1155021_3	204669.Acid345_1255	9.368e-94	317.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria,2JHZ6@204432|Acidobacteriia	204432|Acidobacteriia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
LZS1_k127_1155021_9	670487.Ocepr_1601	4.354e-50	189.0	COG0522@1|root,COG0522@2|Bacteria,1WINE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
LZS1_k127_1155021_16	760142.Hipma_1351	1.581e-41	156.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2WPH1@28221|Deltaproteobacteria,2M769@213113|Desulfurellales	28221|Deltaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
LZS1_k127_1155021_17	1089553.Tph_c25600	1.205e-39	151.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,42G97@68295|Thermoanaerobacterales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
LZS1_k127_1155021_30	243275.TDE_0788	2.034e-12	71.0	COG0257@1|root,COG0257@2|Bacteria,2J989@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
LZS1_k127_1155021_22	96561.Dole_0729	1.494e-29	118.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MKKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
LZS1_k127_1155021_4	1278073.MYSTI_04616	9.216e-91	306.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2YU2D@29|Myxococcales	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
LZS1_k127_1155021_12	622312.ROSEINA2194_02071	9.27e-49	199.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
LZS1_k127_1155021_0	1121405.dsmv_3570	2.252e-147	479.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MHM9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
LZS1_k127_1155021_19	867903.ThesuDRAFT_00577	1.948e-36	146.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WD6M@538999|Clostridiales incertae sedis	186801|Clostridia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
LZS1_k127_1155021_11	643648.Slip_2220	4.35e-49	181.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,42JVW@68298|Syntrophomonadaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS5 family	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
LZS1_k127_1155021_21	935840.JAEQ01000024_gene4128	3.545e-34	134.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2U9A6@28211|Alphaproteobacteria,43K70@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
LZS1_k127_1155021_13	1041147.AUFB01000016_gene1263	1.61e-46	175.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2TV09@28211|Alphaproteobacteria,4BA0W@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
LZS1_k127_1155021_15	292459.STH3061	2.859e-42	161.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
LZS1_k127_1155021_28	886293.Sinac_0472	1.698e-20	91.0	COG0199@1|root,COG0199@2|Bacteria,2J0QE@203682|Planctomycetes	203682|Planctomycetes	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
LZS1_k127_1155021_6	330214.NIDE1323	2.177e-60	216.0	COG0094@1|root,COG0094@2|Bacteria,3J0HN@40117|Nitrospirae	40117|Nitrospirae	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
LZS1_k127_1155021_25	458233.MCCL_0206	3.397e-24	105.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli,4GZ3Q@90964|Staphylococcaceae	91061|Bacilli	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
LZS1_k127_1155021_10	1034345.CAEM01000014_gene173	3.808e-49	179.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CVUJ@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
LZS1_k127_1155021_26	309803.CTN_1002	2e-22	100.0	COG0186@1|root,COG0186@2|Bacteria,2GD97@200918|Thermotogae	200918|Thermotogae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
LZS1_k127_1155021_31	925409.KI911562_gene3026	2.902e-05	50.0	COG0255@1|root,COG0255@2|Bacteria,4P9VV@976|Bacteroidetes,1IU24@117747|Sphingobacteriia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
LZS1_k127_1155021_8	273068.TTE2285	9.915e-54	193.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,42G0F@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
LZS1_k127_1155021_5	1449126.JQKL01000050_gene2681	1.472e-68	241.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,2680N@186813|unclassified Clostridiales	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
LZS1_k127_1155021_29	796940.HMPREF9628_00441	1.629e-15	81.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,25TKT@186804|Peptostreptococcaceae	186801|Clostridia	J	Ribosomal protein L22p/L17e	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
LZS1_k127_1155021_20	521674.Plim_0481	7.049e-36	138.0	COG0185@1|root,COG0185@2|Bacteria,2J0BB@203682|Planctomycetes	203682|Planctomycetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
LZS1_k127_1155021_2	1408322.JHYK01000004_gene865	4.709e-100	338.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,27J0H@186928|unclassified Lachnospiraceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
LZS1_k127_1155021_27	1123256.KB907961_gene537	2.557e-22	102.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1X7HR@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
LZS1_k127_1155021_14	292459.STH3074	5.361e-44	167.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
LZS1_k127_1155021_7	1394178.AWOO02000003_gene2748	8.029e-57	207.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4EIEQ@85012|Streptosporangiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
LZS1_k127_1155021_18	443143.GM18_0831	6.057e-39	147.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2WP4K@28221|Deltaproteobacteria,43SKA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
LZS1_k127_1155021_24	930169.B5T_03809	4.961e-26	107.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1XH22@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS1_k127_1155088_4	383372.Rcas_3448	2.162e-26	111.0	COG0123@1|root,COG0123@2|Bacteria,2G89I@200795|Chloroflexi,376ST@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS1_k127_1155088_0	1313265.JNIE01000004_gene528	1.517e-108	363.0	COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae	200783|Aquificae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS1_k127_1155088_6	301.JNHE01000004_gene1746	5.599e-07	60.0	COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1YFXQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	RDD family	VP2641	-	-	-	-	-	-	-	-	-	-	-	RDD
LZS1_k127_1155088_1	1169144.KB910959_gene3968	2.754e-76	262.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,1ZB14@1386|Bacillus	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
LZS1_k127_1155088_2	1415779.JOMH01000001_gene376	1.496e-54	194.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,1X5ZW@135614|Xanthomonadales	135614|Xanthomonadales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
LZS1_k127_1155088_3	717231.Flexsi_0452	1.143e-52	192.0	COG0250@1|root,COG0250@2|Bacteria,2GEPJ@200930|Deferribacteres	200930|Deferribacteres	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
LZS1_k127_1155088_8	319795.Dgeo_0644	4.522e-05	49.0	COG0690@1|root,COG0690@2|Bacteria,1WKRY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
LZS1_k127_1155088_7	555079.Toce_2106	8.843e-07	53.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,42H2H@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
LZS1_k127_1155088_5	204669.Acid345_1224	1.285e-25	106.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria,2JKFY@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS1_k127_1160182_2	867903.ThesuDRAFT_01773	2.141e-08	57.0	COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,24IHQ@186801|Clostridia	186801|Clostridia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS1_k127_1160182_1	172045.KS04_03100	1.133e-36	148.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,1I8J7@117743|Flavobacteriia,34S6K@308865|Elizabethkingia	976|Bacteroidetes	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
LZS1_k127_1160182_0	313628.LNTAR_24723	1.435e-97	331.0	COG0820@1|root,COG0820@2|Bacteria	2|Bacteria	J	rRNA (adenine-C2-)-methyltransferase activity	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
LZS1_k127_1167545_1	443143.GM18_2129	3.715e-29	119.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,1QUWM@1224|Proteobacteria,43BRB@68525|delta/epsilon subdivisions,2WJJ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,Acyltransferase,FabA,KAsynt_C_assoc,Ketoacyl-synt_C,PS-DH,ketoacyl-synt
LZS1_k127_1167545_2	289376.THEYE_A1907	1.622e-12	78.0	COG1470@1|root,COG1470@2|Bacteria,3J1FN@40117|Nitrospirae	40117|Nitrospirae	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
LZS1_k127_1167545_0	316067.Geob_3147	3.651e-260	841.0	COG0236@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,43W01@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,FabA,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
LZS1_k127_1181195_3	304371.MCP_1701	6.376e-17	89.0	arCOG03980@1|root,arCOG03980@2157|Archaea	2157|Archaea	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_1181195_5	1041826.FCOL_01620	2.539e-09	65.0	2EKBF@1|root,33E1U@2|Bacteria,4NXYA@976|Bacteroidetes,1IDB5@117743|Flavobacteriia,2NXXH@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1181195_0	264462.Bd1198	5.375e-90	311.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2MTNC@213481|Bdellovibrionales,2WJ0A@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
LZS1_k127_1181195_1	330214.NIDE3623	2.542e-74	274.0	COG0656@1|root,COG0656@2|Bacteria	2|Bacteria	S	aldo-keto reductase (NADP) activity	ytbE	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,DUF4157
LZS1_k127_1181195_4	287986.DV20_23840	1.391e-09	71.0	COG3409@1|root,COG3409@2|Bacteria,2GMGY@201174|Actinobacteria	201174|Actinobacteria	M	Fungal chitosanase of glycosyl hydrolase group 75	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_75
LZS1_k127_1181195_6	592028.GCWU000321_00522	5.207e-05	56.0	COG3409@1|root,COG3584@1|root,COG3409@2|Bacteria,COG3584@2|Bacteria,1UV4J@1239|Firmicutes,4H4W0@909932|Negativicutes	909932|Negativicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	3D,PG_binding_1
LZS1_k127_1181195_2	665571.STHERM_c12220	2.248e-27	116.0	COG2703@1|root,COG2703@2|Bacteria,2J7CC@203691|Spirochaetes	203691|Spirochaetes	P	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
LZS1_k127_1181361_5	743721.Psesu_0166	1.566e-70	252.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1X4BE@135614|Xanthomonadales	135614|Xanthomonadales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
LZS1_k127_1181361_7	1304275.C41B8_17828	2.855e-25	108.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
LZS1_k127_1181361_2	1382306.JNIM01000001_gene876	3.258e-79	277.0	COG0384@1|root,COG0384@2|Bacteria,2G7RE@200795|Chloroflexi	200795|Chloroflexi	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
LZS1_k127_1181361_8	1463861.JNXE01000050_gene86	6.43e-06	59.0	COG3568@1|root,COG3568@2|Bacteria,2GNF9@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS1_k127_1181361_4	671143.DAMO_2910	3.006e-78	267.0	2EHMT@1|root,33BDH@2|Bacteria	2|Bacteria	S	Alternative oxidase	-	-	-	-	-	-	-	-	-	-	-	-	AOX
LZS1_k127_1181361_1	580332.Slit_0721	1.56e-110	379.0	COG0842@1|root,COG0842@2|Bacteria,1PX28@1224|Proteobacteria,2VYZC@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
LZS1_k127_1181361_0	1123401.JHYQ01000014_gene822	2.047e-114	376.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,461ME@72273|Thiotrichales	72273|Thiotrichales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS1_k127_1181361_6	572547.Amico_1775	3.615e-35	143.0	COG1943@1|root,COG1943@2|Bacteria,3TC5I@508458|Synergistetes	508458|Synergistetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
LZS1_k127_1181361_3	748280.NH8B_0055	2.028e-78	266.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VHAC@28216|Betaproteobacteria,2KQFQ@206351|Neisseriales	206351|Neisseriales	E	Cys Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
LZS1_k127_1188156_6	765420.OSCT_2410	1.205e-39	151.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
LZS1_k127_1188156_9	575589.HMPREF0018_01048	2.583e-16	88.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,3NII0@468|Moraxellaceae	1236|Gammaproteobacteria	T	Signal transducing histidine kinase, homodimeric domain	chpA	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
LZS1_k127_1188156_0	401526.TcarDRAFT_1563	2.534e-144	482.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
LZS1_k127_1188156_3	373903.Hore_05990	9.598e-67	258.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3WAFC@53433|Halanaerobiales	186801|Clostridia	U	PFAM Bacterial type II secretion system protein F domain	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
LZS1_k127_1188156_11	262724.TT_C0723	5.915e-05	57.0	COG0849@1|root,COG0849@2|Bacteria,1WJ8M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
LZS1_k127_1188156_4	243231.GSU2028	9.115e-43	174.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43UJ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
LZS1_k127_1188156_5	1303518.CCALI_00874	5.931e-41	173.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS1_k127_1188156_2	426117.M446_0877	1.812e-73	261.0	COG0745@1|root,COG1235@1|root,COG2203@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,COG2203@2|Bacteria,1NW4Z@1224|Proteobacteria,2U14Z@28211|Alphaproteobacteria,1JWZZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	KT	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS1_k127_1188156_8	522306.CAP2UW1_3137	1.682e-22	101.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_1188156_1	1254432.SCE1572_52300	8.214e-109	366.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WNH1@28221|Deltaproteobacteria,2Z329@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
LZS1_k127_1188156_7	404589.Anae109_1449	5.246e-33	142.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS1_k127_1188156_10	452662.SJA_C1-01760	7.971e-06	50.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2K1JP@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	dnaJ_2	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
LZS1_k127_1194442_5	869213.JCM21142_72577	1.398e-07	63.0	COG1502@1|root,COG1502@2|Bacteria,4NRMR@976|Bacteroidetes,47QHV@768503|Cytophagia	976|Bacteroidetes	I	PLD-like domain	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS1_k127_1194442_4	237368.SCABRO_02139	2.494e-20	104.0	COG1502@1|root,COG1502@2|Bacteria,2J3HM@203682|Planctomycetes	203682|Planctomycetes	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
LZS1_k127_1194442_2	1206741.BAFX01000031_gene7673	5.006e-42	171.0	COG0515@1|root,COG0515@2|Bacteria,2GJTV@201174|Actinobacteria,4FVEP@85025|Nocardiaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10
LZS1_k127_1194442_3	251221.35212388	1.505e-37	150.0	COG1846@1|root,COG1846@2|Bacteria,1G6XI@1117|Cyanobacteria	1117|Cyanobacteria	K	MarR family transcriptional	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
LZS1_k127_1194442_1	685727.REQ_42380	4.518e-82	280.0	COG1741@1|root,COG1741@2|Bacteria,2GJV3@201174|Actinobacteria,4FU43@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
LZS1_k127_1194442_0	562970.Btus_2136	7.243e-111	383.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,277VF@186823|Alicyclobacillaceae	91061|Bacilli	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
LZS1_k127_1199590_1	204669.Acid345_2517	3.374e-09	63.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
LZS1_k127_1199590_0	292459.STH843	1.202e-30	138.0	COG2203@1|root,COG5002@1|root,COG5278@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
LZS1_k127_12081_3	215803.DB30_1542	4.85e-52	194.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2YW0C@29|Myxococcales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
LZS1_k127_12081_0	749927.AMED_7922	5.447e-224	713.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4E0IR@85010|Pseudonocardiales	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD1	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS1_k127_12081_2	342113.DM82_5593	3.073e-61	222.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,1K3TY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
LZS1_k127_12081_1	1121405.dsmv_1899	2.99e-88	305.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WIN1@28221|Deltaproteobacteria,2MIW0@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM pyruvate carboxyltransferase	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
LZS1_k127_12081_5	504472.Slin_3643	2.81e-28	121.0	COG2259@1|root,COG2259@2|Bacteria,4NK73@976|Bacteroidetes,47QQ2@768503|Cytophagia	976|Bacteroidetes	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_12081_4	910964.GEAM_3585	1.562e-36	143.0	COG0454@1|root,COG0456@2|Bacteria,1N6BV@1224|Proteobacteria,1SAMT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS1_k127_1220088_0	485918.Cpin_4916	0.00021	56.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,4NKIP@976|Bacteroidetes,1IW86@117747|Sphingobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
LZS1_k127_1234931_0	316067.Geob_2770	1.866e-66	242.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
LZS1_k127_1234931_1	1397666.RS24_01665	1.62e-36	156.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,4BQ3I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
LZS1_k127_1234931_2	498848.TaqDRAFT_4855	8.128e-15	81.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
LZS1_k127_1235189_1	7897.ENSLACP00000018270	4.438e-11	72.0	COG0666@1|root,KOG0504@2759|Eukaryota,3A0WN@33154|Opisthokonta,3BPHY@33208|Metazoa,3CY26@33213|Bilateria,482UZ@7711|Chordata,491NZ@7742|Vertebrata	33208|Metazoa	S	ankyrin repeat, SAM and basic leucine zipper	ASZ1	GO:0000003,GO:0000280,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007140,GO:0007276,GO:0007281,GO:0007283,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016070,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030154,GO:0032259,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0034587,GO:0034641,GO:0034660,GO:0035770,GO:0036464,GO:0043046,GO:0043170,GO:0043186,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044728,GO:0045495,GO:0046483,GO:0048232,GO:0048285,GO:0048468,GO:0048609,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0060293,GO:0071546,GO:0071704,GO:0071840,GO:0090304,GO:0140013,GO:1901360,GO:1903046,GO:1990904	-	ko:K18410	-	-	-	-	ko00000,ko03036	-	-	-	Ank_2,Ank_3,Ank_4,SAM_1,SAM_2
LZS1_k127_1235189_0	1121423.JONT01000015_gene1332	5.904e-58	228.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,260VW@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	isp	-	3.4.21.62	ko:K01342,ko:K13275	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	CHB_HEX_C_1,Inhibitor_I9,Peptidase_S8
LZS1_k127_1235189_2	1196323.ALKF01000193_gene3259	4.451e-09	65.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,26VXT@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS1_k127_1248906_1	945713.IALB_1339	2.483e-64	226.0	COG0302@1|root,COG0302@2|Bacteria	2|Bacteria	H	gtp cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
LZS1_k127_1248906_0	525909.Afer_0724	8.149e-92	319.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4CMUJ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
LZS1_k127_1248906_2	869210.Marky_1650	1.399e-34	143.0	COG0580@1|root,COG0580@2|Bacteria,1WKA2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
LZS1_k127_1268136_3	331678.Cphamn1_0895	7.95e-50	194.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	cdu2	-	-	ko:K05564,ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6,2.A.63.1	-	-	Na_H_Exchanger,Usp
LZS1_k127_1268136_0	1191523.MROS_2036	1.603e-106	370.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	mscM	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS1_k127_1268136_1	443144.GM21_3060	2.897e-91	316.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
LZS1_k127_1268136_2	580340.Tlie_0701	8.02e-89	302.0	COG0330@1|root,COG0330@2|Bacteria,3TAJM@508458|Synergistetes	508458|Synergistetes	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS1_k127_1268136_4	1201290.M902_1686	1.123e-32	131.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
LZS1_k127_1292568_2	1408322.JHYK01000003_gene1051	5.309e-17	83.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,27IWC@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
LZS1_k127_1292568_3	870187.Thini_1288	1.082e-13	78.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
LZS1_k127_1292568_0	247490.KSU1_B0536	2.651e-59	221.0	COG3637@1|root,COG3637@2|Bacteria,2IYBM@203682|Planctomycetes	203682|Planctomycetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
LZS1_k127_1292568_1	1125863.JAFN01000001_gene2792	3.289e-40	154.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2WKKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
LZS1_k127_139174_4	477974.Daud_2151	3.074e-80	278.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,26028@186807|Peptococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
LZS1_k127_139174_0	903818.KI912268_gene1811	3.3e-153	502.0	COG2326@1|root,COG2326@2|Bacteria,3Y5E4@57723|Acidobacteria	57723|Acidobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
LZS1_k127_139174_5	314254.OA2633_02226	7.737e-24	117.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,43XS6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF502)	MA20_12960	-	-	-	-	-	-	-	-	-	-	-	DUF502
LZS1_k127_139174_2	589873.EP13_08465	2.318e-129	448.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,1RMEN@1236|Gammaproteobacteria,463Y3@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
LZS1_k127_139174_3	290318.Cvib_1268	2.254e-103	355.0	COG1966@1|root,COG1966@2|Bacteria	2|Bacteria	T	Carbon starvation protein	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
LZS1_k127_139174_1	518766.Rmar_0394	1.281e-131	433.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1FIW1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Na+ dependent nucleoside transporter C-terminus	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
LZS1_k127_1418255_1	269799.Gmet_3221	1.478e-54	199.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_1418255_0	443144.GM21_4147	3.216e-191	613.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,43TF6@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
LZS1_k127_1418255_2	1410630.JNKP01000004_gene430	3.61e-24	113.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,27IR1@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
LZS1_k127_1438768_11	1232410.KI421428_gene1129	1.418e-13	77.0	COG2050@1|root,COG2050@2|Bacteria,1NHB0@1224|Proteobacteria,42XCC@68525|delta/epsilon subdivisions,2WTEP@28221|Deltaproteobacteria,43UMX@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS1_k127_1438768_4	1340493.JNIF01000004_gene761	4.951e-111	368.0	COG1858@1|root,COG1858@2|Bacteria,3Y46D@57723|Acidobacteria	57723|Acidobacteria	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS1_k127_1438768_13	671143.DAMO_1867	2.698e-08	66.0	COG4191@1|root,COG4191@2|Bacteria,2NR0D@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HDOD,HisKA,Response_reg
LZS1_k127_1438768_0	204669.Acid345_1381	2.016e-186	595.0	COG1012@1|root,COG1012@2|Bacteria,3Y384@57723|Acidobacteria,2JIA8@204432|Acidobacteriia	204432|Acidobacteriia	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.32,1.2.1.39,1.2.1.8,1.2.1.85	ko:K00128,ko:K00130,ko:K00146,ko:K10217	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00362,ko00380,ko00410,ko00561,ko00620,ko00622,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00362,map00380,map00410,map00561,map00620,map00622,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130,map01220	M00038,M00135,M00555,M00569	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02762,R02940,R02957,R03283,R03869,R03889,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R05353,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00254,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS1_k127_1438768_5	1519464.HY22_11400	1.024e-79	281.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	paaF	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692,ko:K01715,ko:K07534	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01220,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212,map01220	M00032,M00087,M00540	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R05600,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02034,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS1_k127_1438768_8	926554.KI912633_gene3902	4.147e-64	229.0	COG1024@1|root,COG1024@2|Bacteria,1WIYN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Enoyl-CoA hydratase isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
LZS1_k127_1438768_7	862908.BMS_2002	3.512e-68	243.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,43187@68525|delta/epsilon subdivisions,2WWG4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phenylacetic acid catabolic protein	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
LZS1_k127_1438768_12	1234364.AMSF01000055_gene1051	1.757e-09	71.0	COG1807@1|root,COG1807@2|Bacteria,1RHMW@1224|Proteobacteria,1SPI6@1236|Gammaproteobacteria,1X6CV@135614|Xanthomonadales	135614|Xanthomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_1438768_2	391625.PPSIR1_39700	8.034e-115	387.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2Z1PP@29|Myxococcales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM,TPR_14,TPR_16
LZS1_k127_1438768_6	1380370.JIBA01000011_gene3295	2.426e-75	265.0	COG1250@1|root,COG1250@2|Bacteria,2GPFP@201174|Actinobacteria,4FF7A@85021|Intrasporangiaceae	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
LZS1_k127_1438768_3	1320556.AVBP01000012_gene3572	1.977e-112	377.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
LZS1_k127_1438768_9	483219.LILAB_21020	6.804e-40	157.0	COG0546@1|root,COG0546@2|Bacteria,1P19B@1224|Proteobacteria,431NT@68525|delta/epsilon subdivisions,2WWU8@28221|Deltaproteobacteria,2YVRG@29|Myxococcales	28221|Deltaproteobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1438768_1	1297742.A176_06867	1.151e-128	426.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,42QEQ@68525|delta/epsilon subdivisions,2WQEB@28221|Deltaproteobacteria,2YTVI@29|Myxococcales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	glp	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
LZS1_k127_1438768_10	1121920.AUAU01000003_gene1176	5.321e-17	91.0	COG2271@1|root,COG2271@2|Bacteria,3Y7AA@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
LZS1_k127_1441382_0	1267533.KB906738_gene2257	2.61e-120	396.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
LZS1_k127_1441382_1	483219.LILAB_31320	7.389e-33	141.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
LZS1_k127_1466305_0	1437425.CSEC_1623	1.052e-92	332.0	COG1290@1|root,COG1290@2|Bacteria,2JFNC@204428|Chlamydiae	204428|Chlamydiae	C	Cytochrome b/b6/petB	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
LZS1_k127_1466305_1	671143.DAMO_1672	9.402e-37	145.0	COG0723@1|root,COG0723@2|Bacteria,2NRUZ@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
LZS1_k127_1466305_2	1237149.C900_05483	3.775e-07	54.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
LZS1_k127_1483808_6	1122217.KB899569_gene860	1.694e-05	53.0	COG3018@1|root,COG3018@2|Bacteria,1V907@1239|Firmicutes,4H4Y8@909932|Negativicutes	909932|Negativicutes	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
LZS1_k127_1483808_4	469383.Cwoe_0848	2.251e-11	72.0	COG2161@1|root,COG2161@2|Bacteria,2HRW6@201174|Actinobacteria,4CTZM@84995|Rubrobacteria	84995|Rubrobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
LZS1_k127_1483808_3	1403948.Q618_VCMC00001G0190	6.601e-13	74.0	COG2026@1|root,COG2026@2|Bacteria,2GSVC@201174|Actinobacteria,4D6ET@85005|Actinomycetales	201174|Actinobacteria	DJ	toxin, RelE StbE family	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
LZS1_k127_1483808_2	118173.KB235914_gene2725	3.19e-44	162.0	COG4679@1|root,COG4679@2|Bacteria,1G6N5@1117|Cyanobacteria,1HC3R@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
LZS1_k127_1483808_1	243231.GSU0687	3.578e-97	338.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,43UJ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NmrA-like family	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
LZS1_k127_1483808_0	497965.Cyan7822_0557	1.425e-112	370.0	COG0535@1|root,COG0535@2|Bacteria,1G1TV@1117|Cyanobacteria,3KHBW@43988|Cyanothece	1117|Cyanobacteria	S	TIGRFAM hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Fer4_14,Radical_SAM
LZS1_k127_1499240_2	404380.Gbem_1023	3.184e-23	108.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,42UGM@68525|delta/epsilon subdivisions,2WQR2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS1_k127_1499240_7	1219065.VPR01S_07_01030	6.366e-11	73.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1XXTP@135623|Vibrionales	135623|Vibrionales	J	COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
LZS1_k127_1499240_4	101510.RHA1_ro05622	8.709e-15	81.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4FU16@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_1499240_3	880073.Calab_2217	1.8e-20	102.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
LZS1_k127_1499240_6	882083.SacmaDRAFT_2647	7.942e-12	80.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,2GNGF@201174|Actinobacteria,4ECXP@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Copper-bind,DUF1080
LZS1_k127_1499240_0	1121335.Clst_1392	1.654e-23	109.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3WIJY@541000|Ruminococcaceae	186801|Clostridia	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	arlR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_1499240_5	1379698.RBG1_1C00001G1334	1.359e-13	79.0	COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria	2|Bacteria	I	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
LZS1_k127_1499382_3	1451261.AS96_13225	2.329e-07	56.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4FNV7@85023|Microbacteriaceae	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
LZS1_k127_1499382_2	1304275.C41B8_14440	1.646e-36	147.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4,Sterile
LZS1_k127_1499382_1	1304275.C41B8_14445	3.374e-58	208.0	COG0558@1|root,COG0558@2|Bacteria,1P1W5@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS1_k127_1499382_0	1502724.FF80_03139	2.268e-102	344.0	COG3842@1|root,COG3842@2|Bacteria,1MVS0@1224|Proteobacteria,2TRG2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE
LZS1_k127_1513984_3	383372.Rcas_0677	6.175e-28	123.0	COG1051@1|root,COG1051@2|Bacteria,2G9EQ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS1_k127_1513984_4	497965.Cyan7822_4006	1.116e-16	93.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1G2P9@1117|Cyanobacteria,3KFSV@43988|Cyanothece	1117|Cyanobacteria	MT	MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
LZS1_k127_1513984_0	251221.35211847	5.457e-47	188.0	COG2258@1|root,COG2258@2|Bacteria,1G4BR@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
LZS1_k127_1513984_2	1280954.HPO_04960	1.77e-30	130.0	COG2267@1|root,COG2267@2|Bacteria,1R9GQ@1224|Proteobacteria,2U3YF@28211|Alphaproteobacteria,43X16@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
LZS1_k127_1513984_1	525904.Tter_1216	5.967e-32	132.0	COG0542@1|root,COG0542@2|Bacteria,2NNNE@2323|unclassified Bacteria	2|Bacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS1_k127_1514006_0	1123377.AUIV01000007_gene1324	1.618e-32	134.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1X499@135614|Xanthomonadales	135614|Xanthomonadales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS1_k127_1515970_4	926567.TheveDRAFT_0178	2.01e-24	112.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,3TAJE@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
LZS1_k127_1515970_1	370438.PTH_1130	2.624e-116	389.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,260PN@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
LZS1_k127_1515970_3	883126.HMPREF9710_01487	2.972e-42	165.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,472F1@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
LZS1_k127_1515970_2	1121468.AUBR01000014_gene2233	4.087e-110	378.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,42ER2@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
LZS1_k127_1515970_0	1267535.KB906767_gene3079	5.288e-119	391.0	COG2876@1|root,COG2876@2|Bacteria,3Y32G@57723|Acidobacteria,2JIXH@204432|Acidobacteriia	204432|Acidobacteriia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS1_k127_1516558_0	1125863.JAFN01000001_gene944	5.286e-82	282.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,42N3C@68525|delta/epsilon subdivisions,2WKCB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	-	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
LZS1_k127_1516558_2	652103.Rpdx1_2120	4.788e-12	79.0	2EB14@1|root,3351Z@2|Bacteria,1NG2T@1224|Proteobacteria,2UU2T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1516558_1	861299.J421_6047	3.336e-72	263.0	COG0529@1|root,COG0529@2|Bacteria	2|Bacteria	P	adenylylsulfate kinase activity	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,DUF2061
LZS1_k127_1516558_3	502025.Hoch_1577	2.16e-05	57.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS1_k127_1567389_5	1123501.KB902280_gene506	0.0002045	45.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT
LZS1_k127_1567389_0	1245469.S58_47850	7.784e-237	766.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,3JVXA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS1_k127_1567389_3	243159.AFE_2086	6.942e-27	116.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS1_k127_1567389_4	1122137.AQXF01000004_gene1752	5.052e-18	98.0	COG1073@1|root,COG1073@2|Bacteria,1RC0W@1224|Proteobacteria,2U6C5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FG	alpha, beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,Abhydrolase_6,HIT,Hydrolase_4
LZS1_k127_1567389_1	1124780.ANNU01000016_gene1831	4.235e-50	195.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,47R4U@768503|Cytophagia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
LZS1_k127_1567389_2	1288494.EBAPG3_20630	2.33e-42	165.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2VIMK@28216|Betaproteobacteria,3730Q@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	Isochorismatase family	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
LZS1_k127_1574596_2	926560.KE387023_gene1701	0.0009344	46.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_1574596_0	1297742.A176_05599	5.35e-40	170.0	COG0457@1|root,COG1629@1|root,COG0457@2|Bacteria,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria,2YU72@29|Myxococcales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TPR_8,TonB_dep_Rec
LZS1_k127_1574596_1	269799.Gmet_2736	2.557e-06	59.0	COG2984@1|root,COG2984@2|Bacteria,1Q1HH@1224|Proteobacteria,42UE1@68525|delta/epsilon subdivisions,2WR33@28221|Deltaproteobacteria,43UYS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
LZS1_k127_1577701_1	580340.Tlie_0063	0.0006183	48.0	COG1322@1|root,COG1322@2|Bacteria,3T9XJ@508458|Synergistetes	508458|Synergistetes	S	PFAM RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
LZS1_k127_1577701_0	1379698.RBG1_1C00001G0757	3.428e-09	66.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
LZS1_k127_1578126_2	290512.Paes_1145	2.497e-35	152.0	COG1538@1|root,COG1538@2|Bacteria,1FDME@1090|Chlorobi	1090|Chlorobi	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS1_k127_1578126_1	264462.Bd0708	2.182e-60	222.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WM23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	macrolide-specific efflux protein	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
LZS1_k127_1578126_0	264462.Bd0709	1.515e-189	627.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,4308T@68525|delta/epsilon subdivisions,2MTI3@213481|Bdellovibrionales,2X727@28221|Deltaproteobacteria	213481|Bdellovibrionales	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
LZS1_k127_1578126_4	643562.Daes_2099	6.62e-26	119.0	COG0859@1|root,COG0859@2|Bacteria,1N112@1224|Proteobacteria,42MUI@68525|delta/epsilon subdivisions,2WRZM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
LZS1_k127_1578126_3	1379698.RBG1_1C00001G1032	4.426e-26	120.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS1_k127_1578126_5	1248916.ANFY01000004_gene1710	5.869e-05	48.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria,2K4U8@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS1_k127_1588533_0	190486.XAC0045	2.779e-06	59.0	COG3307@1|root,COG3307@2|Bacteria,1QEG3@1224|Proteobacteria,1TEBE@1236|Gammaproteobacteria,1XBIC@135614|Xanthomonadales	135614|Xanthomonadales	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS1_k127_1588533_1	313625.BL107_08019	7.794e-06	59.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria,1GZSF@1129|Synechococcus	1117|Cyanobacteria	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
LZS1_k127_1590410_4	554065.XP_005849352.1	2.534e-12	68.0	COG0160@1|root,KOG1404@2759|Eukaryota,37NZZ@33090|Viridiplantae,34IZU@3041|Chlorophyta	3041|Chlorophyta	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.40,2.6.1.44	ko:K00827	ko00250,ko00260,ko00270,ko00280,ko01100,ko01110,map00250,map00260,map00270,map00280,map01100,map01110	-	R00369,R00372,R02050,R10992	RC00006,RC00008,RC00018,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_1590410_3	1121296.JONJ01000001_gene1824	2.242e-13	82.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,21ZQP@1506553|Lachnoclostridium	186801|Clostridia	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
LZS1_k127_1590410_0	1111479.AXAR01000001_gene175	7.551e-151	491.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HA2Y@91061|Bacilli,27912@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the interconversion of ornithine to glutamate semialdehyde	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
LZS1_k127_1590410_1	537007.BLAHAN_05589	7.219e-97	333.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XZ16@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
LZS1_k127_1590410_2	1304880.JAGB01000003_gene995	2.023e-68	246.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia	186801|Clostridia	P	ABC transporter, solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
LZS1_k127_1597175_0	1244869.H261_07863	1.041e-141	458.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,2U80G@28211|Alphaproteobacteria,2JWB6@204441|Rhodospirillales	204441|Rhodospirillales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS1_k127_1597175_2	1173025.GEI7407_3588	5.693e-30	128.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
LZS1_k127_1597175_3	1121439.dsat_0905	5.502e-28	128.0	COG0546@1|root,COG0546@2|Bacteria,1N0R4@1224|Proteobacteria,42UH8@68525|delta/epsilon subdivisions,2WQPT@28221|Deltaproteobacteria,2M93Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS1_k127_1597175_1	1244869.H261_07833	4.195e-95	323.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2U8UZ@28211|Alphaproteobacteria,2JX6Y@204441|Rhodospirillales	204441|Rhodospirillales	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS1_k127_1606460_3	56780.SYN_00581	4.135e-17	96.0	COG1186@1|root,COG1186@2|Bacteria,1NBAD@1224|Proteobacteria,42UTT@68525|delta/epsilon subdivisions,2WQZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
LZS1_k127_1606460_2	1121920.AUAU01000005_gene1089	7.935e-59	222.0	COG0218@1|root,COG0218@2|Bacteria,3Y4H6@57723|Acidobacteria	57723|Acidobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
LZS1_k127_1606460_0	414684.RC1_3493	3.086e-217	694.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria,2JYHC@204441|Rhodospirillales	204441|Rhodospirillales	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS1_k127_1606460_1	335543.Sfum_2433	8.684e-148	484.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42RS1@68525|delta/epsilon subdivisions,2WNR1@28221|Deltaproteobacteria,2MQVG@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
LZS1_k127_1628506_0	1191523.MROS_2474	7.492e-58	207.0	COG4656@1|root,COG4656@2|Bacteria	2|Bacteria	C	electron transfer activity	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
LZS1_k127_1628506_1	234267.Acid_0708	1.1e-56	206.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
LZS1_k127_1628506_4	32057.KB217478_gene5133	0.0002117	53.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2
LZS1_k127_1628506_3	1110502.TMO_0669	5.111e-09	62.0	COG0025@1|root,COG0664@1|root,COG0025@2|Bacteria,COG0664@2|Bacteria,1MW5T@1224|Proteobacteria,2TSHB@28211|Alphaproteobacteria,2JQD0@204441|Rhodospirillales	204441|Rhodospirillales	PT	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,cNMP_binding
LZS1_k127_1628506_2	477974.Daud_0951	2.594e-15	79.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,260SX@186807|Peptococcaceae	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS1_k127_1642964_0	861299.J421_3613	2.232e-235	737.0	COG3808@1|root,COG3808@2|Bacteria,1ZT09@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
LZS1_k127_1642964_2	1340493.JNIF01000003_gene2978	2.475e-42	160.0	COG0783@1|root,COG0783@2|Bacteria,3Y471@57723|Acidobacteria	57723|Acidobacteria	P	Ferritin-like domain	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
LZS1_k127_1642964_3	857293.CAAU_1949	2.475e-29	121.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,36IQT@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the Fur family	perR	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS1_k127_1642964_1	6412.HelroP154361	1.568e-76	262.0	COG0450@1|root,KOG0852@2759|Eukaryota,38B9P@33154|Opisthokonta,3B9IG@33208|Metazoa,3CS1I@33213|Bilateria	33208|Metazoa	O	Peroxiredoxin	TPX1	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0008379,GO:0009056,GO:0009636,GO:0009987,GO:0010259,GO:0010941,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019725,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0042737,GO:0042743,GO:0042744,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0051920,GO:0055114,GO:0060548,GO:0065007,GO:0065008,GO:0070887,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K20011	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA,Redoxin
LZS1_k127_1644409_1	56107.Cylst_3419	3.601e-07	61.0	COG1538@1|root,COG1538@2|Bacteria,1G0B8@1117|Cyanobacteria,1HJB4@1161|Nostocales	1117|Cyanobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K03287	-	-	-	-	ko00000	1.B.17	-	-	OEP
LZS1_k127_1644409_0	404589.Anae109_0857	6.977e-61	234.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2WIP4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
LZS1_k127_1654556_5	477184.KYC_09826	4.691e-51	197.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2VI6W@28216|Betaproteobacteria,3T1C0@506|Alcaligenaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
LZS1_k127_1654556_6	335543.Sfum_1372	6.184e-45	174.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WM55@28221|Deltaproteobacteria,2MQDQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
LZS1_k127_1654556_1	1396418.BATQ01000025_gene5261	2.751e-107	358.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,2IU92@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
LZS1_k127_1654556_3	1242864.D187_007090	4.88e-89	310.0	COG0500@1|root,COG0500@2|Bacteria,1QX9N@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS1_k127_1654556_2	649747.HMPREF0083_03843	2.099e-93	316.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,26UE9@186822|Paenibacillaceae	91061|Bacilli	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
LZS1_k127_1654556_0	1304885.AUEY01000019_gene1163	1.204e-119	394.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2WJI0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	membrane protein, TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
LZS1_k127_1654556_8	1381123.AYOD01000044_gene1792	1.721e-09	70.0	COG3793@1|root,COG3793@2|Bacteria,1RD1X@1224|Proteobacteria,2U788@28211|Alphaproteobacteria,43KFQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
LZS1_k127_1654556_4	1144275.COCOR_02117	5.069e-61	217.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,43ADI@68525|delta/epsilon subdivisions,2WPU6@28221|Deltaproteobacteria,2Z38F@29|Myxococcales	28221|Deltaproteobacteria	H	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
LZS1_k127_1654556_7	595460.RRSWK_04553	4.279e-22	103.0	COG1216@1|root,COG1216@2|Bacteria,2J0FG@203682|Planctomycetes	203682|Planctomycetes	O	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_21
LZS1_k127_1662430_7	1380394.JADL01000004_gene6061	2.221e-47	185.0	COG4775@1|root,COG4775@2|Bacteria,1RDM0@1224|Proteobacteria	1224|Proteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
LZS1_k127_1662430_4	909663.KI867150_gene2380	2.206e-68	241.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
LZS1_k127_1662430_2	96561.Dole_2899	1.855e-102	344.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
LZS1_k127_1662430_13	696369.KI912183_gene2583	4.189e-21	102.0	COG2440@1|root,COG2440@2|Bacteria,1V6DH@1239|Firmicutes,24NRC@186801|Clostridia,266WY@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K03855	-	-	-	-	ko00000	-	-	-	ETF_QO
LZS1_k127_1662430_0	644966.Tmar_1118	6.135e-118	393.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,2481K@186801|Clostridia	186801|Clostridia	C	FAD dependent oxidoreductase	fixC	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thi4
LZS1_k127_1662430_15	1123360.thalar_01492	1.873e-17	96.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2U98H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	tcrX	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_1662430_3	574087.Acear_0236	3.136e-81	282.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS1_k127_1662430_14	1134912.AJTV01000058_gene4004	8.089e-21	99.0	COG5502@1|root,COG5502@2|Bacteria,1NB8V@1224|Proteobacteria,2U9GZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
LZS1_k127_1662430_1	1000565.METUNv1_03362	7.461e-103	356.0	2ESTR@1|root,33KC5@2|Bacteria,1NHBB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1662430_6	1007103.AFHW01000120_gene694	1.589e-47	189.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli,274WU@186822|Paenibacillaceae	91061|Bacilli	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
LZS1_k127_1662430_8	1267533.KB906733_gene3052	6.043e-45	175.0	COG0037@1|root,COG0037@2|Bacteria,3Y2F2@57723|Acidobacteria,2JHX8@204432|Acidobacteriia	204432|Acidobacteriia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
LZS1_k127_1662430_17	794903.OPIT5_09490	3.284e-07	63.0	COG1714@1|root,COG1714@2|Bacteria,46T8Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
LZS1_k127_1662430_11	483219.LILAB_02730	1.163e-35	151.0	COG0652@1|root,COG0652@2|Bacteria,1RENS@1224|Proteobacteria,42RIB@68525|delta/epsilon subdivisions,2WINS@28221|Deltaproteobacteria,2YZ46@29|Myxococcales	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
LZS1_k127_1662430_12	1121472.AQWN01000002_gene2108	5.83e-27	129.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
LZS1_k127_1662430_16	696369.KI912183_gene2134	9.226e-08	61.0	2E08C@1|root,32VW2@2|Bacteria,1VE5G@1239|Firmicutes,24P9V@186801|Clostridia,262E2@186807|Peptococcaceae	186801|Clostridia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
LZS1_k127_1662430_5	555079.Toce_2177	1.125e-66	239.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,24BP1@186801|Clostridia,42G2U@68295|Thermoanaerobacterales	186801|Clostridia	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS1_k127_1662430_10	246197.MXAN_3705	5.781e-41	171.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WPGK@28221|Deltaproteobacteria,2YTYN@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
LZS1_k127_1662430_9	1121440.AUMA01000002_gene2080	1.373e-43	176.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WIJ8@28221|Deltaproteobacteria,2M82Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
LZS1_k127_1662699_2	264462.Bd0974	2.646e-49	180.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2MURY@213481|Bdellovibrionales,2X5HZ@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS1_k127_1662699_0	266117.Rxyl_1098	4.517e-122	411.0	COG2317@1|root,COG2317@2|Bacteria,2IACE@201174|Actinobacteria,4CPDZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
LZS1_k127_1662699_1	296591.Bpro_2831	4.281e-89	303.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VHAC@28216|Betaproteobacteria,4ACX8@80864|Comamonadaceae	28216|Betaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
LZS1_k127_1693313_1	469371.Tbis_2854	1.601e-24	117.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4DXUE@85010|Pseudonocardiales	201174|Actinobacteria	I	enoyl-CoA hydratase	echA17	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS1_k127_1693313_0	867903.ThesuDRAFT_01144	5.613e-51	200.0	COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,247XS@186801|Clostridia	186801|Clostridia	IQ	Dehydrogenase	ydaD	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS1_k127_1693313_4	1492737.FEM08_30230	6.543e-05	49.0	COG4980@1|root,COG4980@2|Bacteria,4NRSE@976|Bacteroidetes,1I46Y@117743|Flavobacteriia,2NX2B@237|Flavobacterium	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS1_k127_1693313_3	13349.G1X050	2.242e-07	64.0	29R2Z@1|root,2S1T4@2759|Eukaryota,39JIQ@33154|Opisthokonta,3Q3VX@4751|Fungi,3RKZ8@4890|Ascomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1693313_2	1476876.JOJO01000033_gene3952	6.978e-09	66.0	2E520@1|root,32ZV9@2|Bacteria,2ICNI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1726550_0	1128427.KB904821_gene205	3.26e-116	398.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS1_k127_1726550_2	880072.Desac_0013	2.53e-10	74.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2MQ7H@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS1_k127_1726550_1	1192034.CAP_3557	9.299e-31	140.0	COG0535@1|root,COG0535@2|Bacteria,1NDTC@1224|Proteobacteria	1224|Proteobacteria	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_1726550_3	562983.HMPREF0433_00954	1.321e-09	71.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli,3WDZV@539002|Bacillales incertae sedis	91061|Bacilli	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
LZS1_k127_1726550_5	626522.GCWU000325_01173	0.000715	52.0	COG0457@1|root,COG0457@2|Bacteria,4NGGZ@976|Bacteroidetes,2FMHN@200643|Bacteroidia,1WCVK@1283313|Alloprevotella	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8
LZS1_k127_1726550_4	1173020.Cha6605_4542	2.94e-06	52.0	COG0457@1|root,COG0457@2|Bacteria,1G7D9@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_8
LZS1_k127_1741933_0	682795.AciX8_3057	5.451e-166	542.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
LZS1_k127_1741933_4	1123226.KB899277_gene1165	1.141e-33	132.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,26RHB@186822|Paenibacillaceae	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
LZS1_k127_1741933_5	661087.HMPREF1008_01482	6.288e-27	111.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CW78@84998|Coriobacteriia	84998|Coriobacteriia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
LZS1_k127_1741933_3	391625.PPSIR1_07480	7.965e-47	182.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43C3Z@68525|delta/epsilon subdivisions,2X7EF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sensor histidine kinase, HAMP and PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,dCache_3,sCache_3_3
LZS1_k127_1741933_2	562970.Btus_1602	4.467e-65	252.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli,2782Z@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
LZS1_k127_1741933_6	1120965.AUBV01000003_gene550	1.911e-23	102.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,47R37@768503|Cytophagia	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
LZS1_k127_1741933_1	926549.KI421517_gene768	1.302e-127	416.0	COG1064@1|root,COG1064@2|Bacteria,4NFGP@976|Bacteroidetes,47K0T@768503|Cytophagia	976|Bacteroidetes	S	alcohol dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS1_k127_1765149_11	1440053.JOEI01000007_gene2532	1.133e-25	123.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
LZS1_k127_1765149_13	391625.PPSIR1_25681	1.255e-22	112.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS1_k127_1765149_6	1382306.JNIM01000001_gene3149	5.938e-89	315.0	COG0644@1|root,COG0644@2|Bacteria,2G9E5@200795|Chloroflexi	200795|Chloroflexi	C	Tryptophan halogenase	-	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
LZS1_k127_1765149_8	1144275.COCOR_01564	7.592e-59	211.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,42USD@68525|delta/epsilon subdivisions,2WQCM@28221|Deltaproteobacteria,2YXGM@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
LZS1_k127_1765149_3	1242864.D187_005846	4.405e-131	424.0	COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,42S03@68525|delta/epsilon subdivisions,2WNW5@28221|Deltaproteobacteria,2YZ59@29|Myxococcales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS1_k127_1765149_10	404589.Anae109_3198	2.878e-33	144.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS1_k127_1765149_1	483219.LILAB_14525	7.09e-160	518.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2YYF2@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_1765149_0	378806.STAUR_1586	2.297e-168	544.0	COG1012@1|root,COG1012@2|Bacteria,1QWN5@1224|Proteobacteria,43BT3@68525|delta/epsilon subdivisions,2X73T@28221|Deltaproteobacteria,2YYMR@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
LZS1_k127_1765149_2	1242864.D187_005843	8.079e-140	462.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria,2YX29@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_1765149_21	1123371.ATXH01000003_gene1960	0.0009897	48.0	COG0031@1|root,COG0215@1|root,COG0031@2|Bacteria,COG0215@2|Bacteria,2GH4J@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	EJ	Pyridoxal-phosphate dependent enzyme	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
LZS1_k127_1765149_18	1034769.KB910518_gene1558	0.0002627	51.0	29YF4@1|root,30K9R@2|Bacteria,1U094@1239|Firmicutes,4I9K0@91061|Bacilli,271PC@186822|Paenibacillaceae	91061|Bacilli	S	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
LZS1_k127_1765149_17	391625.PPSIR1_01949	1.505e-12	78.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	mftB	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1765149_7	1085623.GNIT_1375	3.436e-68	258.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,4644H@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K01766,ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SufE
LZS1_k127_1765149_14	1192034.CAP_9040	1.511e-21	109.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS1_k127_1765149_9	391625.PPSIR1_25656	2.318e-33	148.0	COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria,42Q23@68525|delta/epsilon subdivisions,2WWQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
LZS1_k127_1765149_12	450851.PHZ_c2419	3.944e-24	113.0	COG0535@1|root,COG0535@2|Bacteria,1ND1B@1224|Proteobacteria,2TV8F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_1765149_20	443152.MDG893_13144	0.0004654	53.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,1RN4R@1236|Gammaproteobacteria,46CB5@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	4Fe-4S single cluster domain	aslB	GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0033554,GO:0043170,GO:0044238,GO:0050896,GO:0051604,GO:0051716,GO:0071704,GO:1901564	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
LZS1_k127_1765149_4	1192034.CAP_2187	8.344e-113	386.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_1765149_5	391625.PPSIR1_25641	8.434e-99	342.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_1765149_16	1342299.Z947_1496	6.936e-17	93.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2U0BU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_1765149_15	1120985.AUMI01000014_gene884	5.082e-18	98.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,4H28Q@909932|Negativicutes	909932|Negativicutes	C	six-Cys-in-45 modification radical SAM protein	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS1_k127_1798196_0	391625.PPSIR1_26703	6.091e-99	333.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YZKE@29|Myxococcales	28221|Deltaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
LZS1_k127_1798196_1	1131269.AQVV01000008_gene943	1.53e-44	174.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
LZS1_k127_1798196_2	74547.PMT_1982	1.787e-22	113.0	COG1807@1|root,COG1807@2|Bacteria,1GCFV@1117|Cyanobacteria,1MNB5@1212|Prochloraceae	1117|Cyanobacteria	M	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_1826525_0	330214.NIDE4018	1.294e-163	531.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS1_k127_1826525_1	144197.XP_008278353.1	1.687e-23	109.0	COG0666@1|root,KOG0504@2759|Eukaryota,39YNX@33154|Opisthokonta,3BFJC@33208|Metazoa,3CU3G@33213|Bilateria,487NG@7711|Chordata,49AM8@7742|Vertebrata,49QII@7898|Actinopterygii	33208|Metazoa	S	Ankyrin repeat domain-containing protein 50-like	ankrd50	-	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	AAA_16,Ank_2,Ank_4
LZS1_k127_1835667_1	1379698.RBG1_1C00001G0500	4.921e-76	273.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS1_k127_1835667_8	1220582.RRU01S_03_00410	3.709e-05	56.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2U6ZQ@28211|Alphaproteobacteria,4B7PV@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
LZS1_k127_1835667_4	1353529.M899_1088	5.649e-28	119.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2MT4C@213481|Bdellovibrionales,2WNZS@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
LZS1_k127_1835667_0	330214.NIDE0478	3.715e-76	265.0	COG0588@1|root,COG0588@2|Bacteria,3J118@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
LZS1_k127_1835667_6	1028801.RG1141_CH27480	2.669e-13	82.0	COG2197@1|root,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,2TTK7@28211|Alphaproteobacteria,4B8HF@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	MA20_23080	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS1_k127_1835667_2	1283300.ATXB01000002_gene2728	9.649e-37	151.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RYYR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,GGDEF,PAS_3,PAS_4,PAS_8,PocR
LZS1_k127_1835667_5	317619.ANKN01000161_gene313	7.847e-21	97.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,1MKDA@1212|Prochloraceae	1117|Cyanobacteria	T	Alternative locus ID	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_1835667_7	1146883.BLASA_1658	4.888e-09	68.0	COG2259@1|root,COG2259@2|Bacteria,2IQEY@201174|Actinobacteria,4ETDJ@85013|Frankiales	201174|Actinobacteria	O	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
LZS1_k127_1835667_3	1089550.ATTH01000001_gene729	3.989e-32	132.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
LZS1_k127_1895017_1	871963.Desdi_2763	7.304e-38	151.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,261GR@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS1_k127_1895017_2	66373.JOFQ01000002_gene5204	3.615e-17	96.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_1895017_0	638303.Thal_0516	1.171e-87	306.0	COG0015@1|root,COG0015@2|Bacteria,2G3Q6@200783|Aquificae	200783|Aquificae	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
LZS1_k127_1899337_1	344747.PM8797T_21513	1.317e-98	334.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
LZS1_k127_1899337_2	1453498.LG45_10710	3.277e-73	276.0	COG2244@1|root,COG2244@2|Bacteria,4NFKD@976|Bacteroidetes,1HZ63@117743|Flavobacteriia,2NVNY@237|Flavobacterium	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	wzxC	-	-	ko:K03328,ko:K16695	-	-	-	-	ko00000,ko02000	2.A.66.2,2.A.66.2.7	-	-	Polysacc_synt_3,Polysacc_synt_C
LZS1_k127_1899337_9	706587.Desti_3022	9.324e-10	70.0	COG0438@1|root,COG0438@2|Bacteria,1PGQE@1224|Proteobacteria,43ABN@68525|delta/epsilon subdivisions,2WY7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1899337_8	562970.Btus_3249	4.119e-18	99.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,4HKBQ@91061|Bacilli,27AE4@186823|Alicyclobacillaceae	91061|Bacilli	T	low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS1_k127_1899337_3	497321.C664_14649	1.675e-47	188.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VIY4@28216|Betaproteobacteria,2KVUX@206389|Rhodocyclales	206389|Rhodocyclales	M	COG2148 Sugar transferases involved in lipopolysaccharide synthesis	sthA	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
LZS1_k127_1899337_6	521011.Mpal_0619	2.419e-35	147.0	COG0463@1|root,arCOG01381@2157|Archaea,2XVM0@28890|Euryarchaeota,2NADC@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_1899337_0	56780.SYN_02667	1.22e-121	401.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,42MJF@68525|delta/epsilon subdivisions,2WPGD@28221|Deltaproteobacteria,2MS5H@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
LZS1_k127_1899337_4	247490.KSU1_C1153	1.181e-42	165.0	29WW7@1|root,30IHV@2|Bacteria,2J3QZ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1899337_7	545264.KB898744_gene2204	1.181e-20	100.0	COG3919@1|root,COG3919@2|Bacteria,1N7HV@1224|Proteobacteria	1224|Proteobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
LZS1_k127_1946461_7	1235793.C809_02391	1.644e-11	67.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia,27NRD@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS1_k127_1946461_8	754476.Q7A_2209	2.257e-06	59.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS1_k127_1946461_2	243231.GSU1113	2.293e-94	318.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
LZS1_k127_1946461_3	1379270.AUXF01000004_gene3068	3.303e-83	286.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_1946461_5	1499967.BAYZ01000004_gene4922	1.022e-69	257.0	28M0D@1|root,2ZAFE@2|Bacteria	2|Bacteria	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
LZS1_k127_1946461_6	471881.PROPEN_00716	1.829e-27	121.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,3Z29R@583|Proteus	1236|Gammaproteobacteria	S	Divergent polysaccharide deacetylase	yibQ	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
LZS1_k127_1946461_4	379066.GAU_2547	1.145e-82	287.0	COG3266@1|root,COG3266@2|Bacteria,1ZT0N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_1946461_1	1173024.KI912153_gene217	2.467e-137	448.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae	1117|Cyanobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS1_k127_1946461_0	1173024.KI912153_gene216	2.484e-271	847.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS1_k127_1963218_6	381764.Fnod_1336	2.055e-07	54.0	COG1351@1|root,COG1351@2|Bacteria,2GC26@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
LZS1_k127_1963218_3	765869.BDW_00945	1.299e-33	137.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2MT6Q@213481|Bdellovibrionales,2WQNR@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
LZS1_k127_1963218_7	484019.THA_433	0.0002041	54.0	COG0845@1|root,COG0845@2|Bacteria,2GD8D@200918|Thermotogae	200918|Thermotogae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS1_k127_1963218_1	1123368.AUIS01000032_gene1396	6.85e-140	456.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,2NBRQ@225057|Acidithiobacillales	1236|Gammaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS1_k127_1963218_4	330214.NIDE1046	2.213e-33	143.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	barA	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
LZS1_k127_1963218_0	96561.Dole_1090	5.102e-229	745.0	COG0745@1|root,COG2804@1|root,COG0745@2|Bacteria,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WKXB@28221|Deltaproteobacteria,2MMWV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE,T2SSE_N
LZS1_k127_1963218_2	357808.RoseRS_4460	2.331e-138	467.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi,3768X@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
LZS1_k127_1963218_5	1121354.AQUV01000001_gene1372	5.795e-17	92.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,22K57@1653|Corynebacteriaceae	201174|Actinobacteria	T	Phosphate starvation-inducible protein PhoH	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
LZS1_k127_197196_2	1458462.JNLK01000001_gene2484	1.158e-05	55.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,27MD3@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
LZS1_k127_197196_1	1121430.JMLG01000003_gene558	9.278e-78	273.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,2606Y@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS1_k127_197196_0	401526.TcarDRAFT_1596	4.264e-170	545.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H236@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
LZS1_k127_1983806_10	665571.STHERM_c04500	0.0002688	44.0	COG0009@1|root,COG0009@2|Bacteria,2J73M@203691|Spirochaetes	203691|Spirochaetes	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
LZS1_k127_1983806_2	1121403.AUCV01000009_gene1455	7.768e-98	338.0	COG3899@1|root,COG4191@1|root,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BKN@68525|delta/epsilon subdivisions,2WJNS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,Pkinase
LZS1_k127_1983806_9	123899.JPQP01000020_gene1985	1.096e-12	78.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,3T25R@506|Alcaligenaceae	28216|Betaproteobacteria	T	Regulator	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
LZS1_k127_1983806_3	1121015.N789_02375	1.593e-80	274.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,1S6M1@1236|Gammaproteobacteria,1XAJC@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
LZS1_k127_1983806_7	1123392.AQWL01000008_gene1245	4.28e-33	128.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VWXC@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
LZS1_k127_1983806_1	194439.CT1726	6.468e-144	466.0	COG0701@1|root,COG0701@2|Bacteria,1FDFM@1090|Chlorobi	1090|Chlorobi	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
LZS1_k127_1983806_4	1163617.SCD_n01989	3.939e-76	259.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,2VTZ5@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
LZS1_k127_1983806_0	357808.RoseRS_1917	4.131e-155	507.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi,37708@32061|Chloroflexia	32061|Chloroflexia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
LZS1_k127_1983806_6	1519464.HY22_09850	5.257e-44	169.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
LZS1_k127_1983806_8	1379270.AUXF01000001_gene2712	9.563e-24	104.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
LZS1_k127_1983806_5	378806.STAUR_6137	2.693e-67	242.0	29UQM@1|root,30G2F@2|Bacteria,1NSCX@1224|Proteobacteria,42YNA@68525|delta/epsilon subdivisions,2WTSS@28221|Deltaproteobacteria,2YYJA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2001221_1	1128421.JAGA01000002_gene1365	3.071e-63	226.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS1_k127_2001221_6	1123234.AUKI01000011_gene1488	0.0007743	49.0	COG4980@1|root,COG4980@2|Bacteria,4NU4D@976|Bacteroidetes,1I4FT@117743|Flavobacteriia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS1_k127_2001221_5	1123511.KB905849_gene3309	3.746e-23	106.0	COG1309@1|root,COG1309@2|Bacteria,1VAVF@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137,ko:K18939	-	M00715	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_13,TetR_N
LZS1_k127_2001221_4	309801.trd_A0739	1.908e-27	118.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,27YHJ@189775|Thermomicrobia	189775|Thermomicrobia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS1_k127_2001221_2	1184267.A11Q_705	1.542e-61	220.0	COG1651@1|root,COG1651@2|Bacteria,1NZPQ@1224|Proteobacteria,42U1T@68525|delta/epsilon subdivisions,2MSXR@213481|Bdellovibrionales,2WQH9@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
LZS1_k127_2001221_3	706587.Desti_5049	5.086e-28	124.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2MS09@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
LZS1_k127_2001221_0	243233.MCA1905	7.58e-93	328.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,1T2RV@1236|Gammaproteobacteria,1XENI@135618|Methylococcales	135618|Methylococcales	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2005480_0	1303518.CCALI_00138	9.802e-120	392.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS1_k127_2005480_1	575540.Isop_3543	1.699e-39	158.0	COG1721@1|root,COG1721@2|Bacteria,2IWV6@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS1_k127_2005480_2	1125863.JAFN01000001_gene501	3.041e-08	64.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	BatA,CARDB,F5_F8_type_C,HemolysinCabind,Laminin_G_3,NIDO,VWA_2
LZS1_k127_2009376_3	693444.D782_1825	1.109e-05	55.0	COG3716@1|root,COG3716@2|Bacteria,1MWTZ@1224|Proteobacteria,1RNSD@1236|Gammaproteobacteria,282J9@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	G	PFAM PTS system mannose fructose sorbose family IID component	manZ	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	iECIAI1_1343.ECIAI1_1888,iECP_1309.ECP_1762,iSBO_1134.SBO_1231,iSF_1195.SF1409,iSFxv_1172.SFxv_1596,iS_1188.S1524	EIID-AGA
LZS1_k127_2009376_2	497964.CfE428DRAFT_4274	4.861e-21	103.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM phosphocarrier, HPr family	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
LZS1_k127_2009376_0	1031288.AXAA01000009_gene666	3.715e-149	492.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
LZS1_k127_2009376_1	867903.ThesuDRAFT_00677	4.132e-140	481.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WCEY@538999|Clostridiales incertae sedis	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
LZS1_k127_2013558_12	404589.Anae109_2792	3.746e-14	86.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS1_k127_2013558_3	521674.Plim_2955	1.528e-63	230.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
LZS1_k127_2013558_1	64471.sync_2126	1.377e-162	530.0	COG0843@1|root,COG0843@2|Bacteria,1G1ME@1117|Cyanobacteria,1GZH3@1129|Synechococcus	1117|Cyanobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	cyoB	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
LZS1_k127_2013558_9	1123060.JONP01000066_gene829	1.317e-24	113.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MVYW@1224|Proteobacteria,2TS8D@28211|Alphaproteobacteria,2JVKC@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cytochrom_C,Cytochrome_CBB3
LZS1_k127_2013558_8	478741.JAFS01000002_gene875	8.492e-27	126.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia,37GTT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS1_k127_2013558_15	502025.Hoch_2422	0.0002001	48.0	2EAMQ@1|root,334Q9@2|Bacteria,1NA2T@1224|Proteobacteria,42VC9@68525|delta/epsilon subdivisions,2WTH0@28221|Deltaproteobacteria,2YVPQ@29|Myxococcales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
LZS1_k127_2013558_5	671143.DAMO_1164	4.431e-37	147.0	COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria	2|Bacteria	C	cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
LZS1_k127_2013558_11	1121939.L861_22785	1.822e-14	79.0	COG1959@1|root,COG1959@2|Bacteria,1RGUG@1224|Proteobacteria	1224|Proteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS1_k127_2013558_2	1163617.SCD_n00383	8.56e-79	271.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VQMN@28216|Betaproteobacteria	28216|Betaproteobacteria	O	anaerobic ribonucleoside-triphosphate reductase activating protein	nrdG	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_2013558_10	1163617.SCD_n00384	2.453e-20	91.0	COG1328@1|root,COG1328@2|Bacteria,1N8MB@1224|Proteobacteria,2VW43@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	-	-	-	-	-	-	-	-	-	-	-	-	NRDD
LZS1_k127_2013558_0	1123368.AUIS01000008_gene2160	0.0	1125.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,1RNHS@1236|Gammaproteobacteria,2NCRR@225057|Acidithiobacillales	225057|Acidithiobacillales	F	ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
LZS1_k127_2013558_7	42345.XP_008777423.1	5.002e-27	128.0	COG1535@1|root,2QQB1@2759|Eukaryota,37IJ0@33090|Viridiplantae,3GBAF@35493|Streptophyta,3KNR3@4447|Liliopsida	35493|Streptophyta	Q	Isochorismatase family	-	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009117,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019362,GO:0019637,GO:0019674,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	Isochorismatase
LZS1_k127_2013558_4	1231241.Mc24_01489	2.619e-61	234.0	COG0820@1|root,COG0820@2|Bacteria,2GC4T@200918|Thermotogae	200918|Thermotogae	J	PFAM Radical SAM domain protein	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	-
LZS1_k127_2013558_6	1232410.KI421424_gene1702	3.286e-29	136.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,43S0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS1_k127_2013558_13	631454.N177_0933	3.033e-09	66.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2U36S@28211|Alphaproteobacteria,1JPCH@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	fixK	-	-	ko:K01420,ko:K15861	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS1_k127_2013558_14	1122611.KB903950_gene6441	7.723e-05	49.0	COG0457@1|root,COG0457@2|Bacteria,2I0V5@201174|Actinobacteria,4EFNJ@85012|Streptosporangiales	201174|Actinobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_8
LZS1_k127_2055342_3	1449126.JQKL01000018_gene3274	9.715e-15	86.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,268F5@186813|unclassified Clostridiales	186801|Clostridia	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
LZS1_k127_2055342_5	459349.CLOAM0344	3.364e-07	61.0	COG2980@1|root,COG2980@2|Bacteria,2NQ1I@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
LZS1_k127_2055342_0	215803.DB30_3811	0.0	1084.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2YU4U@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
LZS1_k127_2055342_2	867903.ThesuDRAFT_00415	1.253e-32	145.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,3WCZA@538999|Clostridiales incertae sedis	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
LZS1_k127_2055342_1	1122917.KB899679_gene475	2.497e-57	215.0	2BISW@1|root,32D0M@2|Bacteria,1U2JG@1239|Firmicutes,4IC71@91061|Bacilli,27284@186822|Paenibacillaceae	91061|Bacilli	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
LZS1_k127_2055342_4	1232410.KI421418_gene2408	3.883e-09	68.0	COG3507@1|root,COG4733@1|root,COG3507@2|Bacteria,COG4733@2|Bacteria,1RDH5@1224|Proteobacteria	1224|Proteobacteria	G	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1349
LZS1_k127_2073278_0	498761.HM1_1471	3.618e-177	565.0	COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,25F02@186801|Clostridia	186801|Clostridia	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS1_k127_2073278_3	234267.Acid_1395	2.873e-06	61.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
LZS1_k127_2073278_1	671143.DAMO_0210	4.422e-71	254.0	COG0438@1|root,COG0438@2|Bacteria,2NR2T@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS1_k127_2073278_2	742817.HMPREF9449_01629	1.297e-14	87.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes,2FP4W@200643|Bacteroidia,22X5F@171551|Porphyromonadaceae	976|Bacteroidetes	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
LZS1_k127_2074860_3	693746.OBV_00700	2.026e-25	112.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,2N6B1@216572|Oscillospiraceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS1_k127_2074860_1	243231.GSU0031	2.711e-58	216.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43TH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
LZS1_k127_2074860_0	1123499.KB908019_gene2266	2e-67	237.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,2KQ20@206351|Neisseriales	206351|Neisseriales	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS1_k127_2074860_2	797209.ZOD2009_11920	3.939e-48	190.0	COG1960@1|root,arCOG04100@2157|Archaea,2XTBC@28890|Euryarchaeota,23U9N@183963|Halobacteria	183963|Halobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
LZS1_k127_2076839_1	357808.RoseRS_2380	6.385e-29	128.0	COG0297@1|root,COG0297@2|Bacteria,2GBMD@200795|Chloroflexi,37794@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS1_k127_2076839_0	1123242.JH636434_gene4755	5.82e-40	168.0	COG0500@1|root,COG2226@2|Bacteria,2J52Z@203682|Planctomycetes	203682|Planctomycetes	Q	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS1_k127_2076839_2	1173025.GEI7407_3138	2.12e-16	94.0	COG0392@1|root,COG0392@2|Bacteria,1GAD9@1117|Cyanobacteria,1HDT1@1150|Oscillatoriales	1117|Cyanobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS1_k127_2076839_3	1242864.D187_000710	8.406e-14	84.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS1_k127_207772_1	1125863.JAFN01000001_gene3341	3.406e-70	254.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
LZS1_k127_207772_0	521098.Aaci_1269	3.462e-76	269.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,2797Y@186823|Alicyclobacillaceae	91061|Bacilli	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
LZS1_k127_207772_2	498761.HM1_2050	5.005e-17	82.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
LZS1_k127_2078666_3	1384054.N790_03075	1.474e-105	347.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1X38D@135614|Xanthomonadales	135614|Xanthomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS1_k127_2078666_4	1458275.AZ34_07525	1.445e-93	314.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,4AARP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
LZS1_k127_2078666_7	765911.Thivi_0253	1.399e-21	108.0	2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,1SCY7@1236|Gammaproteobacteria,1WYDM@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
LZS1_k127_2078666_0	1121918.ARWE01000001_gene186	4.089e-127	428.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,42N4S@68525|delta/epsilon subdivisions,2WJXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS1_k127_2078666_2	1458275.AZ34_07520	1.239e-110	372.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,4AC6Q@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS1_k127_2078666_6	1384056.N787_00680	4.3e-39	153.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	5.3.3.1	ko:K01822,ko:K21972	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	SnoaL_2
LZS1_k127_2078666_5	338966.Ppro_0126	3.498e-55	207.0	COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,431QN@68525|delta/epsilon subdivisions,2WX4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
LZS1_k127_2078666_1	344747.PM8797T_00899	4.091e-120	400.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
LZS1_k127_2085946_7	1123519.PSJM300_17195	8.892e-15	77.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1Z1UZ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
LZS1_k127_2085946_4	1183438.GKIL_1553	3.025e-55	212.0	COG1472@1|root,COG1472@2|Bacteria,1G29F@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Glycosyl hydrolase family 3 N terminal domain	bgl	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Glyco_hydro_3
LZS1_k127_2085946_2	583355.Caka_0857	6.07e-90	314.0	COG0591@1|root,COG0591@2|Bacteria,46ZB9@74201|Verrucomicrobia,3K8WD@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS1_k127_2085946_1	748247.AZKH_1490	2.495e-91	321.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2VMMF@28216|Betaproteobacteria,2KXTY@206389|Rhodocyclales	206389|Rhodocyclales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343
LZS1_k127_2085946_9	330214.NIDE2765	1.136e-10	74.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	cycH	-	3.4.21.105	ko:K02200,ko:K04018,ko:K19225,ko:K20543,ko:K21007	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.55.3	-	-	TPR_16,TPR_19,TPR_2,TPR_8
LZS1_k127_2085946_10	1297581.H919_00405	1.527e-06	59.0	COG5521@1|root,COG5521@2|Bacteria,1V2MC@1239|Firmicutes,4HGIF@91061|Bacilli,21VM7@150247|Anoxybacillus	91061|Bacilli	S	Protein of unknown function (DUF1189)	yqgB	-	-	-	-	-	-	-	-	-	-	-	DUF1189
LZS1_k127_2085946_3	344747.PM8797T_04795	9.852e-60	222.0	COG0842@1|root,COG0842@2|Bacteria,2IZDF@203682|Planctomycetes	203682|Planctomycetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS1_k127_2085946_0	204669.Acid345_2220	4.168e-98	331.0	COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_2085946_5	404589.Anae109_3587	2.82e-48	181.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
LZS1_k127_2085946_6	1268635.Loa_01512	1.595e-36	151.0	2FI84@1|root,34A0N@2|Bacteria,1QYAX@1224|Proteobacteria,1SSRH@1236|Gammaproteobacteria,1JGPC@118969|Legionellales	118969|Legionellales	S	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
LZS1_k127_2085946_8	1278073.MYSTI_02455	1.381e-12	80.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS1_k127_2093923_1	1379698.RBG1_1C00001G1458	2.438e-118	391.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS1_k127_2093923_3	235909.GK3395	4.301e-98	327.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1WFG8@129337|Geobacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
LZS1_k127_2093923_5	1122611.KB903974_gene3026	1.238e-46	192.0	COG1506@1|root,COG1506@2|Bacteria,2I6NU@201174|Actinobacteria,4EI10@85012|Streptosporangiales	201174|Actinobacteria	E	Tannase and feruloyl esterase	-	-	-	-	-	-	-	-	-	-	-	-	3HBOH,Tannase
LZS1_k127_2093923_2	1095769.CAHF01000011_gene2479	3.415e-110	362.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2VH6T@28216|Betaproteobacteria,473WD@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
LZS1_k127_2093923_8	398767.Glov_3037	1.959e-34	142.0	COG0593@1|root,COG1943@1|root,COG0593@2|Bacteria,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
LZS1_k127_2093923_0	1242864.D187_004550	2.547e-228	715.0	COG1509@1|root,COG1509@2|Bacteria,1R8HT@1224|Proteobacteria,43DMX@68525|delta/epsilon subdivisions,2X6DS@28221|Deltaproteobacteria,2YUSV@29|Myxococcales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	kamA1	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C
LZS1_k127_2093923_11	665571.STHERM_c20850	9.697e-16	87.0	2E1HF@1|root,32WVJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3996
LZS1_k127_2093923_7	522306.CAP2UW1_2075	1.178e-34	144.0	COG0457@1|root,COG3012@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3012@2|Bacteria,COG3903@2|Bacteria,1MWRF@1224|Proteobacteria,2VVW1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_7
LZS1_k127_2093923_9	670487.Ocepr_0039	2.039e-30	140.0	COG0642@1|root,COG2205@2|Bacteria	670487.Ocepr_0039|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2093923_10	1541065.JRFE01000032_gene3642	1.057e-16	85.0	COG0745@1|root,COG2198@1|root,COG4566@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG4566@2|Bacteria,1G027@1117|Cyanobacteria,3VM7C@52604|Pleurocapsales	1117|Cyanobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Hpt,Response_reg,Trans_reg_C
LZS1_k127_2093923_6	1118060.CAGZ01000005_gene1633	5.941e-41	160.0	COG0745@1|root,COG0745@2|Bacteria,2IGXT@201174|Actinobacteria,4CV7C@84998|Coriobacteriia	84998|Coriobacteriia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_2093923_4	1458427.BAWN01000021_gene1378	8.347e-52	188.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,4ADJA@80864|Comamonadaceae	28216|Betaproteobacteria	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
LZS1_k127_2093923_12	1201290.M902_0803	1.228e-13	83.0	2CH0S@1|root,341IR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2134737_2	767434.Fraau_2187	3.972e-08	60.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,1X8A4@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
LZS1_k127_2134737_4	1227484.C471_05391	0.0008386	52.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota,23SIB@183963|Halobacteria	183963|Halobacteria	C	COG1413 FOG HEAT repeat	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
LZS1_k127_2134737_0	391625.PPSIR1_34287	2.498e-28	132.0	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,42TPV@68525|delta/epsilon subdivisions,2WQ3P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS1_k127_2134737_1	436717.AOLE_09580	3.148e-14	82.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S9IM@1236|Gammaproteobacteria,3NN7B@468|Moraxellaceae	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	exbD1	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS1_k127_2134737_3	1550073.JROH01000001_gene564	0.0002586	53.0	COG0810@1|root,COG0810@2|Bacteria,1NH16@1224|Proteobacteria,2UKYU@28211|Alphaproteobacteria,2K637@204457|Sphingomonadales	204457|Sphingomonadales	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS1_k127_2135024_0	1173264.KI913949_gene3735	5.077e-83	296.0	COG0465@1|root,COG0465@2|Bacteria,1G1S2@1117|Cyanobacteria,1H842@1150|Oscillatoriales	1117|Cyanobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH4	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
LZS1_k127_2170300_1	1129374.AJE_07131	3.633e-65	233.0	COG0648@1|root,COG0648@2|Bacteria,1R6X2@1224|Proteobacteria,1RSJ8@1236|Gammaproteobacteria,465V6@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Domain of unknown function (DUF4862)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4862
LZS1_k127_2170300_4	582744.Msip34_0895	3.885e-26	112.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,2KMX2@206350|Nitrosomonadales	206350|Nitrosomonadales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
LZS1_k127_2170300_7	448385.sce0605	4.092e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2YVS5@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
LZS1_k127_2170300_6	745411.B3C1_14982	3.965e-09	63.0	2C0Z2@1|root,32WKV@2|Bacteria,1N218@1224|Proteobacteria,1SAVY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3293)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3293
LZS1_k127_2170300_3	876044.IMCC3088_970	6.067e-30	122.0	COG1487@1|root,COG1487@2|Bacteria,1MZZ9@1224|Proteobacteria,1SDG0@1236|Gammaproteobacteria,1JB8U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS1_k127_2170300_5	316067.Geob_3269	1.629e-11	70.0	COG5450@1|root,COG5450@2|Bacteria,1Q2TR@1224|Proteobacteria,42W8I@68525|delta/epsilon subdivisions,2WRTI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
LZS1_k127_2170300_2	264201.pc1296	5.626e-41	167.0	COG1994@1|root,COG1994@2|Bacteria,2JFYC@204428|Chlamydiae	204428|Chlamydiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
LZS1_k127_2170300_0	1089551.KE386572_gene2883	1.102e-170	542.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2TT2F@28211|Alphaproteobacteria,4BQ4B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	nemA	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
LZS1_k127_2178222_0	1121403.AUCV01000008_gene1584	3.346e-37	153.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MJU3@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS1_k127_2178222_1	760142.Hipma_1113	8.492e-23	100.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2WQYK@28221|Deltaproteobacteria,2M7C1@213113|Desulfurellales	28221|Deltaproteobacteria	M	SpoVG	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
LZS1_k127_2178348_0	502025.Hoch_6480	1.039e-218	711.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS1_k127_2178589_1	105420.BBPO01000032_gene6549	6.631e-53	195.0	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria,2NHTE@228398|Streptacidiphilus	201174|Actinobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
LZS1_k127_2178589_2	1042377.AFPJ01000024_gene698	8.269e-10	66.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,468UE@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
LZS1_k127_2178589_0	1499967.BAYZ01000158_gene455	2.515e-103	353.0	COG1570@1|root,COG1570@2|Bacteria,2NNQT@2323|unclassified Bacteria	2|Bacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
LZS1_k127_2192232_5	1379698.RBG1_1C00001G0776	1.366e-05	57.0	COG2864@1|root,COG2864@2|Bacteria,2NNNM@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b subunit of formate dehydrogenase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
LZS1_k127_2192232_0	595460.RRSWK_06726	3.529e-184	586.0	COG0372@1|root,COG0372@2|Bacteria,2IYFN@203682|Planctomycetes	203682|Planctomycetes	H	citrate synthase	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS1_k127_2192232_4	765910.MARPU_00410	3.989e-14	79.0	COG0457@1|root,COG0457@2|Bacteria,1RESK@1224|Proteobacteria,1S41N@1236|Gammaproteobacteria,1WYBB@135613|Chromatiales	135613|Chromatiales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
LZS1_k127_2192232_1	246197.MXAN_1795	5.105e-103	343.0	2BRF1@1|root,32KDW@2|Bacteria,1Q2SY@1224|Proteobacteria,438ER@68525|delta/epsilon subdivisions,2X3PP@28221|Deltaproteobacteria,2YWSS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2192232_2	627192.SLG_11520	5.681e-64	224.0	28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,2U8ZT@28211|Alphaproteobacteria,2K4I9@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2192232_3	1173026.Glo7428_0554	1.317e-26	114.0	COG2940@1|root,COG2940@2|Bacteria	2|Bacteria	K	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
LZS1_k127_2204745_3	1121920.AUAU01000008_gene1615	4.078e-46	172.0	COG3303@1|root,COG3303@2|Bacteria,3Y9EA@57723|Acidobacteria	57723|Acidobacteria	P	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
LZS1_k127_2204745_0	1297742.A176_05070	6.115e-255	820.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	iron-sulfur binding	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS1_k127_2204745_1	1278073.MYSTI_06131	2.965e-211	664.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2YU0I@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
LZS1_k127_2204745_4	1278073.MYSTI_06130	1.594e-37	147.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	actD	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS1_k127_2204745_2	1125863.JAFN01000001_gene2793	3.597e-51	203.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS1_k127_2218845_1	304371.MCP_2273	1.386e-59	222.0	arCOG00787@1|root,arCOG00787@2157|Archaea	2157|Archaea	L	UvrD REP helicase	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS1_k127_2218845_0	1232410.KI421421_gene3677	1.075e-97	333.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,43S79@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,Methyltransf_25
LZS1_k127_2231758_3	269799.Gmet_0576	1.027e-16	96.0	COG4386@1|root,COG4733@1|root,COG4386@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Malectin,NPCBM,Phage-tail_3,fn3
LZS1_k127_2231758_2	219305.MCAG_02724	2.316e-32	136.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4D8UG@85008|Micromonosporales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_2231758_0	644966.Tmar_1258	1.475e-184	611.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia	186801|Clostridia	I	PFAM Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS1_k127_2231758_4	1165096.ARWF01000001_gene153	7.825e-05	53.0	COG1388@1|root,COG4254@1|root,COG1388@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,2KN17@206350|Nitrosomonadales	206350|Nitrosomonadales	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
LZS1_k127_2231758_1	1150474.JQJI01000005_gene299	1.852e-113	378.0	COG0162@1|root,COG0162@2|Bacteria,2GCKH@200918|Thermotogae	200918|Thermotogae	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iLJ478.TM0478	S4,tRNA-synt_1b
LZS1_k127_2242316_1	194439.CT0111	1.553e-05	55.0	COG4747@1|root,COG4747@2|Bacteria,1FF4Y@1090|Chlorobi	1090|Chlorobi	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
LZS1_k127_2242316_0	1123368.AUIS01000007_gene2732	7.094e-54	198.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,1S0NW@1236|Gammaproteobacteria,2NBVS@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Iron/manganese superoxide dismutases, C-terminal domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
LZS1_k127_2246767_4	694431.DESACE_00730	8.69e-17	96.0	COG1502@1|root,COG1502@2|Bacteria,1RK7U@1224|Proteobacteria,42WC8@68525|delta/epsilon subdivisions,2X6NZ@28221|Deltaproteobacteria,2M75H@213113|Desulfurellales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
LZS1_k127_2246767_2	1128421.JAGA01000002_gene1498	2.618e-22	114.0	COG1502@1|root,COG1502@2|Bacteria,2NQ5Z@2323|unclassified Bacteria	2|Bacteria	I	PLD-like domain	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS1_k127_2246767_3	485913.Krac_1470	2.073e-20	101.0	COG0724@1|root,COG0724@2|Bacteria,2G74A@200795|Chloroflexi	200795|Chloroflexi	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS1_k127_2246767_0	667632.KB890165_gene2241	1.705e-62	234.0	COG3300@1|root,COG4251@1|root,COG3300@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VJGY@28216|Betaproteobacteria,1KGEK@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_9,TarH
LZS1_k127_2246767_1	552811.Dehly_1481	9.032e-39	153.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
LZS1_k127_2278175_0	903818.KI912268_gene2561	6.655e-177	568.0	COG0514@1|root,COG0514@2|Bacteria,3Y2KM@57723|Acidobacteria	57723|Acidobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RecQ_Zn_bind
LZS1_k127_2278175_1	1244869.H261_01836	1.657e-112	370.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2TSEB@28211|Alphaproteobacteria,2JQH4@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
LZS1_k127_2278175_2	1009370.ALO_01205	1.711e-90	312.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,4H2TU@909932|Negativicutes	1239|Firmicutes	M	Monogalactosyldiacylglycerol synthase, C-terminal domain protein	ypfP	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
LZS1_k127_2284126_0	1123368.AUIS01000027_gene1347	4.602e-78	267.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,1RN24@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	L-2-hydroxyglutarate oxidase LhgO	lhgO	GO:0000166,GO:0003674,GO:0003824,GO:0003973,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016614,GO:0016899,GO:0034419,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071944,GO:0097159,GO:1901265,GO:1901363	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
LZS1_k127_2284126_2	1232410.KI421412_gene82	7.29e-14	75.0	COG2026@1|root,COG2026@2|Bacteria,1NP1I@1224|Proteobacteria,437H9@68525|delta/epsilon subdivisions,2WVKQ@28221|Deltaproteobacteria,43V3Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
LZS1_k127_2284126_1	1123371.ATXH01000027_gene168	1.158e-38	151.0	COG0691@1|root,COG0691@2|Bacteria,2GH3M@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
LZS1_k127_2284126_3	243277.VC_2423	1.376e-10	68.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SBN6@1236|Gammaproteobacteria,1Y2DJ@135623|Vibrionales	135623|Vibrionales	NU	Pilin (bacterial filament)	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
LZS1_k127_2284195_13	1341151.ASZU01000010_gene1964	2.967e-05	53.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,27BB2@186824|Thermoactinomycetaceae	91061|Bacilli	I	Thiolase, C-terminal domain	pcaF	-	2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K02615	ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS1_k127_2284195_8	1521187.JPIM01000131_gene1453	1.232e-25	117.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi,377ME@32061|Chloroflexia	32061|Chloroflexia	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
LZS1_k127_2284195_9	1123405.AUMM01000008_gene992	3.389e-20	98.0	COG5496@1|root,COG5496@2|Bacteria,1UH3T@1239|Firmicutes,4HJC5@91061|Bacilli	91061|Bacilli	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS1_k127_2284195_5	1340493.JNIF01000003_gene2631	2.28e-58	220.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfbU	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS1_k127_2284195_4	319795.Dgeo_1883	4.473e-64	237.0	COG0183@1|root,COG0183@2|Bacteria	2|Bacteria	I	Belongs to the thiolase family	phaA	GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS1_k127_2284195_3	941449.dsx2_0219	1.712e-71	251.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2M7XS@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	TIGRFAM Tyrosine recombinase XerD	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS1_k127_2284195_1	1009370.ALO_19932	2.912e-138	448.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4H2TB@909932|Negativicutes	909932|Negativicutes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
LZS1_k127_2284195_11	1120968.AUBX01000011_gene3261	3.238e-17	84.0	COG0449@1|root,COG0449@2|Bacteria,4PKBN@976|Bacteroidetes	976|Bacteroidetes	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
LZS1_k127_2284195_10	1268240.ATFI01000008_gene2399	3.385e-18	93.0	COG1502@1|root,COG1502@2|Bacteria,4PPQS@976|Bacteroidetes,2G18B@200643|Bacteroidia	976|Bacteroidetes	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
LZS1_k127_2284195_6	484770.UFO1_4750	2.492e-31	137.0	COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4H4VY@909932|Negativicutes	909932|Negativicutes	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
LZS1_k127_2284195_7	1223523.H340_24670	3.007e-28	129.0	COG2242@1|root,COG2242@2|Bacteria,2I33T@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
LZS1_k127_2284195_0	251221.35212631	2.004e-315	987.0	COG0542@1|root,COG0542@2|Bacteria,1G0ZH@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS1_k127_2284195_12	1298593.TOL_2406	1.566e-14	86.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,1XIXC@135619|Oceanospirillales	135619|Oceanospirillales	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	2.6.1.84	ko:K12252,ko:K14261	ko00330,ko01100,map00330,map01100	-	R08197	RC00006,RC00008	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_2284195_2	1298867.AUES01000001_gene1649	3.711e-94	335.0	COG0421@1|root,COG0421@2|Bacteria,1PD54@1224|Proteobacteria,2V9CT@28211|Alphaproteobacteria,3JYAK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
LZS1_k127_2293791_8	1442599.JAAN01000020_gene2548	0.0001024	46.0	COG4403@1|root,COG4403@2|Bacteria,1NCPK@1224|Proteobacteria,1SCTX@1236|Gammaproteobacteria,1X6HK@135614|Xanthomonadales	135614|Xanthomonadales	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2293791_3	234267.Acid_7663	6.221e-131	426.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
LZS1_k127_2293791_0	448385.sce4721	5.443e-214	689.0	COG1953@1|root,COG1953@2|Bacteria,1MV18@1224|Proteobacteria,42X2Z@68525|delta/epsilon subdivisions,2WTRX@28221|Deltaproteobacteria,2YTSH@29|Myxococcales	28221|Deltaproteobacteria	FH	Permease for cytosine/purines, uracil, thiamine, allantoin	-	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
LZS1_k127_2293791_1	234267.Acid_7659	2.02e-166	535.0	COG0044@1|root,COG0044@2|Bacteria,3Y48H@57723|Acidobacteria	57723|Acidobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
LZS1_k127_2293791_7	96561.Dole_2900	1.488e-69	256.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
LZS1_k127_2293791_5	96561.Dole_2900	4.192e-73	264.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
LZS1_k127_2293791_6	96561.Dole_2900	4.294e-73	263.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
LZS1_k127_2293791_2	204669.Acid345_1459	9.601e-144	471.0	COG1012@1|root,COG1012@2|Bacteria,3Y3V5@57723|Acidobacteria,2JIX2@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.2.1.28	ko:K00141,ko:K22187	ko00040,ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00040,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667,R11768	RC00075,RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS1_k127_2293791_4	1396141.BATP01000059_gene2568	1.574e-105	366.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS1_k127_2309984_2	1280952.HJA_08529	1.272e-19	92.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,43XWG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
LZS1_k127_2309984_0	319795.Dgeo_0422	1.796e-46	189.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3335,Peptidase_C39_2
LZS1_k127_2309984_1	909663.KI867150_gene688	9.202e-27	127.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	ydhO	-	3.4.14.13	ko:K20742,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SLH
LZS1_k127_2313695_0	554065.XP_005848278.1	8.968e-65	246.0	COG0439@1|root,2RN4Y@2759|Eukaryota,37Z96@33090|Viridiplantae,34JVG@3041|Chlorophyta	3041|Chlorophyta	F	ATP-grasp domain	-	-	6.3.2.11	ko:K14755	ko00330,ko00340,ko00410,map00330,map00340,map00410	-	R00910,R00912,R01164,R01991,R03286	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_4
LZS1_k127_2313695_1	497964.CfE428DRAFT_3137	2.069e-61	217.0	2AQME@1|root,31FUG@2|Bacteria,46VH0@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2313695_2	1340493.JNIF01000003_gene4460	2.307e-32	141.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
LZS1_k127_2313695_3	1396141.BATP01000007_gene5742	7.11e-26	111.0	COG2941@1|root,COG2941@2|Bacteria	2|Bacteria	H	ubiquinone biosynthetic process	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
LZS1_k127_2314259_1	1288826.MSNKSG1_03670	9.425e-68	238.0	COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,1T268@1236|Gammaproteobacteria,466KQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG0421 Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
LZS1_k127_2314259_3	1293054.HSACCH_01400	5.221e-47	193.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WAHY@53433|Halanaerobiales	186801|Clostridia	T	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS1_k127_2314259_4	886293.Sinac_2399	2.267e-29	130.0	COG1408@1|root,COG1408@2|Bacteria,2J015@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS1_k127_2314259_2	358396.C445_00280	3.304e-49	192.0	COG0665@1|root,arCOG00755@2157|Archaea,2XUM9@28890|Euryarchaeota,23S19@183963|Halobacteria	183963|Halobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	solA	-	-	-	-	-	-	-	-	-	-	-	DAO
LZS1_k127_2314259_0	1517416.IDAT_02810	2.018e-99	329.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,2QEZ3@267893|Idiomarinaceae	1236|Gammaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_436,iECOK1_1307.ECOK1_1491,iECS88_1305.ECS88_1416,iJN746.PP_2112,iUMN146_1321.UM146_10390,iUTI89_1310.UTI89_C1547	Aconitase,Aconitase_C
LZS1_k127_2326851_2	1168065.DOK_12701	8.459e-31	137.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,1JA1B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	ShlB
LZS1_k127_2326851_1	1123389.ATXJ01000018_gene970	9.904e-80	276.0	COG0685@1|root,COG0685@2|Bacteria,1WI80@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
LZS1_k127_2326851_4	317936.Nos7107_1804	6.213e-19	103.0	COG0457@1|root,COG0457@2|Bacteria,1G1PV@1117|Cyanobacteria,1HJ37@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_2326851_3	1210884.HG799476_gene15395	1.693e-26	128.0	COG0457@1|root,COG0457@2|Bacteria,2IZWD@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_2326851_0	671143.DAMO_2934	4.268e-103	346.0	COG0667@1|root,COG0667@2|Bacteria,2NS4R@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	ydjG	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS1_k127_2332476_0	404589.Anae109_3433	1.903e-103	347.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS1_k127_2332476_1	484770.UFO1_1113	5.766e-31	124.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,4H57U@909932|Negativicutes	909932|Negativicutes	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
LZS1_k127_2332476_2	350688.Clos_1361	2.031e-17	83.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,36DTB@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
LZS1_k127_2335542_1	1337936.IJ00_19060	1.178e-83	285.0	COG0412@1|root,COG0412@2|Bacteria,1G4HV@1117|Cyanobacteria,1HMQR@1161|Nostocales	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
LZS1_k127_2335542_0	502025.Hoch_4095	3.12e-121	394.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,42NYT@68525|delta/epsilon subdivisions,2WIM3@28221|Deltaproteobacteria,2Z34A@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
LZS1_k127_2402180_1	553184.ATORI0001_0777	5.732e-17	86.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,4CVTV@84998|Coriobacteriia	84998|Coriobacteriia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
LZS1_k127_2402180_0	525904.Tter_0485	3.071e-124	419.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,zf-C4_Topoisom
LZS1_k127_2445661_3	1459636.NTE_02622	8.123e-19	89.0	COG0316@1|root,arCOG04560@2157|Archaea,41SKH@651137|Thaumarchaeota	651137|Thaumarchaeota	O	Iron-sulfur cluster assembly accessory protein	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
LZS1_k127_2445661_2	1469245.JFBG01000021_gene1200	1.59e-19	96.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,1WYPN@135613|Chromatiales	135613|Chromatiales	C	Iron--sulfur cluster insertion protein erpA	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
LZS1_k127_2445661_1	1403819.BATR01000098_gene3260	3.873e-37	143.0	COG2322@1|root,COG2322@2|Bacteria,46SZT@74201|Verrucomicrobia,2IUT2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF420
LZS1_k127_2445661_0	448385.sce4838	3.384e-74	257.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
LZS1_k127_2446596_1	228410.NE2076	1.99e-08	68.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,373ZZ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
LZS1_k127_2446596_0	1303518.CCALI_01551	5.927e-59	229.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	kinB	-	2.7.13.3	ko:K11383	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,KinB_sensor,PAS,PAS_4
LZS1_k127_2513821_0	880073.Calab_2474	3.672e-58	224.0	COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria	2|Bacteria	NU	von Willebrand factor (vWF) type A domain	batA	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
LZS1_k127_2513821_2	880074.BARVI_00715	3.866e-15	85.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia,22XR6@171551|Porphyromonadaceae	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2513821_1	309807.SRU_2573	1.176e-26	114.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,1FIVV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS1_k127_2526689_1	429009.Adeg_1845	1.364e-58	212.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,42F7P@68295|Thermoanaerobacterales	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
LZS1_k127_2526689_2	518766.Rmar_2816	1.503e-29	130.0	COG5632@1|root,COG5632@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447,ko:K17733	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01002,ko01011	-	-	-	Amidase_2,Big_2
LZS1_k127_2526689_0	1121930.AQXG01000006_gene782	6.154e-91	314.0	COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,1IPQC@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase M24B, X-Pro dipeptidase aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
LZS1_k127_2526689_3	1173028.ANKO01000090_gene3474	5.654e-14	80.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1G4N6@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
LZS1_k127_2532487_7	330214.NIDE2074	4.106e-36	137.0	COG1697@1|root,COG1697@2|Bacteria	2|Bacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF2220,DUF3322,TP6A_N
LZS1_k127_2532487_10	247490.KSU1_D0151	3.422e-21	108.0	29FE7@1|root,302BX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2532487_0	497964.CfE428DRAFT_1743	6.268e-211	674.0	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia	74201|Verrucomicrobia	E	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
LZS1_k127_2532487_11	1191523.MROS_2823	8.068e-20	102.0	COG2956@1|root,COG2956@2|Bacteria	2|Bacteria	G	lipopolysaccharide metabolic process	-	-	-	ko:K08309,ko:K19804	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
LZS1_k127_2532487_5	526218.Sterm_3155	1.999e-67	242.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS1_k127_2532487_3	1382306.JNIM01000001_gene1839	6.35e-82	286.0	COG1063@1|root,COG1063@2|Bacteria,2G6PM@200795|Chloroflexi	200795|Chloroflexi	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS1_k127_2532487_4	546274.EIKCOROL_00778	2.496e-73	273.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,2KPEC@206351|Neisseriales	206351|Neisseriales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
LZS1_k127_2532487_6	667014.Thein_0397	4.358e-39	164.0	COG0307@1|root,COG0307@2|Bacteria,2GGV7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
LZS1_k127_2532487_2	635013.TherJR_1781	3.119e-154	503.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,260I8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
LZS1_k127_2532487_8	580331.Thit_0024	3.321e-28	121.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,42G01@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
LZS1_k127_2532487_9	562970.Btus_0733	3.181e-23	104.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,278JS@186823|Alicyclobacillaceae	91061|Bacilli	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
LZS1_k127_2532487_1	1415778.JQMM01000001_gene2044	2.052e-156	516.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1J4U2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	iEC55989_1330.EC55989_2701,iECABU_c1320.ECABU_c27320,iECIAI1_1343.ECIAI1_2469,iECO103_1326.ECO103_2930,iECO111_1330.ECO111_3141,iECO26_1355.ECO26_3464,iECSE_1348.ECSE_2702,iECW_1372.ECW_m2640,iEKO11_1354.EKO11_1317,iEcE24377_1341.EcE24377A_2698,iEcSMS35_1347.EcSMS35_2566,iWFL_1372.ECW_m2640,iYL1228.KPN_02758,ic_1306.c2945	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS1_k127_2537457_15	1121920.AUAU01000010_gene44	5.752e-73	258.0	COG0548@1|root,COG0548@2|Bacteria,3Y2IF@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
LZS1_k127_2537457_11	378806.STAUR_5871	1.717e-75	276.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,43BFP@68525|delta/epsilon subdivisions,2WMVT@28221|Deltaproteobacteria,2YY4J@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS1_k127_2537457_10	378806.STAUR_5872	6.45e-92	331.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales	28221|Deltaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
LZS1_k127_2537457_21	398767.Glov_3037	9.052e-41	160.0	COG0593@1|root,COG1943@1|root,COG0593@2|Bacteria,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
LZS1_k127_2537457_27	635013.TherJR_2324	2.682e-16	93.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,260VW@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,Peptidase_S8,SLH
LZS1_k127_2537457_7	1123376.AUIU01000019_gene1247	5.497e-102	357.0	COG5009@1|root,COG5009@2|Bacteria,3J0BH@40117|Nitrospirae	40117|Nitrospirae	M	Penicillin-binding protein OB-like domain	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
LZS1_k127_2537457_16	1089549.AZUQ01000001_gene665	1.476e-51	208.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4EY9U@85014|Glycomycetales	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS1_k127_2537457_9	243090.RB7510	2.519e-92	318.0	COG3876@1|root,COG3876@2|Bacteria,2J50E@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
LZS1_k127_2537457_12	1307761.L21SP2_2601	3.475e-73	255.0	28JYD@1|root,2Z9NN@2|Bacteria	1307761.L21SP2_2601|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2537457_14	649638.Trad_1966	5.732e-73	253.0	COG1814@1|root,COG1814@2|Bacteria,1WMZB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
LZS1_k127_2537457_26	1128421.JAGA01000002_gene308	5.181e-20	105.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_2537457_22	1192034.CAP_1749	5.151e-36	150.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42P0U@68525|delta/epsilon subdivisions,2WJC6@28221|Deltaproteobacteria,2YVSY@29|Myxococcales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS1_k127_2537457_24	555079.Toce_1601	4.602e-25	116.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,42FNR@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM Phosphoribosyltransferase	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
LZS1_k127_2537457_17	292459.STH749	4.737e-50	205.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS1_k127_2537457_1	383372.Rcas_3083	8.599e-152	491.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi,3756K@32061|Chloroflexia	32061|Chloroflexia	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS1_k127_2537457_3	240016.ABIZ01000001_gene2649	8.587e-143	465.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,2IU1R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS1_k127_2537457_4	383372.Rcas_4267	1.652e-138	453.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi,374WM@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS1_k127_2537457_23	1128421.JAGA01000002_gene742	7.159e-27	127.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS1_k127_2537457_2	383372.Rcas_4255	2.13e-145	474.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
LZS1_k127_2537457_8	338963.Pcar_2954	3.992e-94	332.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,43U7I@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Starch synthase catalytic domain	glgA-2	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Alpha-amylase,Glyco_transf_5,Glycos_transf_1
LZS1_k127_2537457_18	1184267.A11Q_518	4.306e-49	188.0	COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,42T7R@68525|delta/epsilon subdivisions,2MTQZ@213481|Bdellovibrionales,2WNQ2@28221|Deltaproteobacteria	213481|Bdellovibrionales	DJ	family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
LZS1_k127_2537457_25	1321778.HMPREF1982_01510	3.186e-24	116.0	COG0477@1|root,COG2814@2|Bacteria,1UZKT@1239|Firmicutes,25EHZ@186801|Clostridia,26BZA@186813|unclassified Clostridiales	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_2537457_0	246197.MXAN_2974	1.45e-230	784.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,CarbopepD_reg_2,Plug
LZS1_k127_2537457_6	1278073.MYSTI_05612	4.144e-115	399.0	COG4122@1|root,COG4122@2|Bacteria,1QWCT@1224|Proteobacteria,43C6D@68525|delta/epsilon subdivisions,2X7GK@28221|Deltaproteobacteria,2Z3G7@29|Myxococcales	28221|Deltaproteobacteria	O	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2537457_28	4577.GRMZM2G542205_P01	0.0004158	52.0	2CBQC@1|root,2QPZN@2759|Eukaryota,37Q5C@33090|Viridiplantae,3GE4H@35493|Streptophyta,3KYJY@4447|Liliopsida,3I9VS@38820|Poales	35493|Streptophyta	S	tetratricopeptide repeat-containing protein	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0008022,GO:0008150,GO:0009987,GO:0030544,GO:0031072,GO:0051087	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
LZS1_k127_2537457_13	518766.Rmar_2557	5.099e-73	261.0	COG2265@1|root,COG2265@2|Bacteria,4NFP1@976|Bacteroidetes,1FJUI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
LZS1_k127_2537457_5	498761.HM1_0969	3.937e-124	407.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
LZS1_k127_2537457_19	1254432.SCE1572_22375	3.987e-48	198.0	COG3055@1|root,COG3227@1|root,COG4412@1|root,COG3055@2|Bacteria,COG3227@2|Bacteria,COG4412@2|Bacteria,1QT4U@1224|Proteobacteria,437RQ@68525|delta/epsilon subdivisions,2X4KF@28221|Deltaproteobacteria,2YZ72@29|Myxococcales	28221|Deltaproteobacteria	E	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2539265_8	1453500.AT05_04455	9.222e-12	65.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1HWUI@117743|Flavobacteriia	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS1_k127_2539265_1	234267.Acid_5619	1.074e-48	177.0	COG0780@1|root,COG0780@2|Bacteria,3Y4ND@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
LZS1_k127_2539265_5	335543.Sfum_2242	5.531e-21	108.0	COG1807@1|root,COG1807@2|Bacteria,1NTFE@1224|Proteobacteria,42Z1W@68525|delta/epsilon subdivisions,2WTMJ@28221|Deltaproteobacteria,2MS6C@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_2539265_10	742727.HMPREF9447_02403	0.0001353	55.0	COG0265@1|root,COG0265@2|Bacteria,4NJVK@976|Bacteroidetes,2FP7N@200643|Bacteroidia,4APAK@815|Bacteroidaceae	976|Bacteroidetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
LZS1_k127_2539265_9	1223521.BBJX01000013_gene479	2.576e-09	62.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,2VI19@28216|Betaproteobacteria,4AB3A@80864|Comamonadaceae	28216|Betaproteobacteria	N	flagellar motor switch protein	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
LZS1_k127_2539265_7	1392502.JNIO01000008_gene1731	3.743e-15	89.0	COG3023@1|root,COG3023@2|Bacteria,1V7WT@1239|Firmicutes,4H4PE@909932|Negativicutes	909932|Negativicutes	V	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
LZS1_k127_2539265_6	186497.PF1401	4.354e-19	94.0	COG1047@1|root,arCOG00980@2157|Archaea,2XTB7@28890|Euryarchaeota,242X3@183968|Thermococci	183968|Thermococci	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
LZS1_k127_2539265_3	1040986.ATYO01000007_gene1062	4.865e-35	137.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,2UBR4@28211|Alphaproteobacteria,43KZ2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Small multidrug resistance protein	sugE	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
LZS1_k127_2539265_0	240015.ACP_2162	1.554e-216	688.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria,2JHV7@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
LZS1_k127_2539265_2	1499967.BAYZ01000088_gene5142	4.028e-39	169.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,2NRIW@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
LZS1_k127_2539265_4	1125863.JAFN01000001_gene2657	3.579e-28	122.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,43BH1@68525|delta/epsilon subdivisions,2X6VI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS1_k127_2541266_1	448385.sce2296	1.816e-61	242.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2YX9T@29|Myxococcales	28221|Deltaproteobacteria	G	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
LZS1_k127_2541266_0	344747.PM8797T_25021	6.13e-90	301.0	COG0421@1|root,COG0421@2|Bacteria,2J4K5@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2541266_2	243231.GSU1444	5.52e-14	80.0	COG2984@1|root,COG2984@2|Bacteria,1Q1HH@1224|Proteobacteria,42UE1@68525|delta/epsilon subdivisions,2WR33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
LZS1_k127_2587033_3	443144.GM21_3423	1.797e-44	184.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,43T9B@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
LZS1_k127_2587033_1	1120746.CCNL01000017_gene3147	1.874e-137	454.0	COG1190@1|root,COG1190@2|Bacteria,2NNMH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
LZS1_k127_2587033_4	945713.IALB_2132	7.324e-23	106.0	COG0745@1|root,COG0745@2|Bacteria	945713.IALB_2132|-	T	phosphorelay signal transduction system	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
LZS1_k127_2587033_5	289376.THEYE_A1337	2.154e-22	102.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	M1-573	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,His_kinase,Response_reg
LZS1_k127_2587033_0	671143.DAMO_1916	9.559e-230	730.0	COG4772@1|root,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
LZS1_k127_2587033_2	1396418.BATQ01000097_gene5956	2.771e-65	236.0	COG4409@1|root,COG4409@2|Bacteria,46V4S@74201|Verrucomicrobia,2IWB9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
LZS1_k127_2613279_2	369723.Strop_4214	2.951e-40	168.0	COG1670@1|root,COG1670@2|Bacteria,2IQ5X@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
LZS1_k127_2613279_3	588596.U9TPY7	9.657e-34	149.0	2CMKB@1|root,2QQNT@2759|Eukaryota,38EY6@33154|Opisthokonta,3NYMZ@4751|Fungi	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_2613279_4	383372.Rcas_3237	0.0002036	53.0	COG1266@1|root,COG1266@2|Bacteria,2G9RS@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS1_k127_2613279_1	926550.CLDAP_10000	4.21e-74	263.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
LZS1_k127_2613279_0	518766.Rmar_1570	1.575e-85	291.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1FIZF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
LZS1_k127_2629163_2	443144.GM21_0115	1.462e-140	465.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,42MEW@68525|delta/epsilon subdivisions,2WJX1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	TIGRFAM Malto-oligosyltrehalose synthase	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
LZS1_k127_2629163_1	575540.Isop_2400	0.0	1037.0	COG1523@1|root,COG1523@2|Bacteria,2IX65@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS1_k127_2629163_0	309801.trd_1931	0.0	1272.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
LZS1_k127_2629163_6	1382359.JIAL01000001_gene1687	6.281e-16	90.0	COG0745@1|root,COG0745@2|Bacteria,3Y4C2@57723|Acidobacteria,2JJ42@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_2629163_5	243231.GSU2567	1.053e-51	203.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,MASE3,PAS_3,PAS_4,PAS_9,dCache_1
LZS1_k127_2629163_3	1353529.M899_3353	1.726e-104	360.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
LZS1_k127_2629163_4	1353529.M899_3354	2.769e-88	297.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
LZS1_k127_2647144_1	443143.GM18_2588	2.269e-43	181.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42QCV@68525|delta/epsilon subdivisions,2WJP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS1_k127_2647144_0	1128421.JAGA01000002_gene1753	6.978e-61	229.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
LZS1_k127_2647144_3	1449126.JQKL01000023_gene173	4.623e-12	77.0	COG1988@1|root,COG1988@2|Bacteria,1TQFC@1239|Firmicutes,24I12@186801|Clostridia,26B7F@186813|unclassified Clostridiales	186801|Clostridia	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
LZS1_k127_2647144_2	459495.SPLC1_S050780	6.64e-22	101.0	COG2402@1|root,COG2402@2|Bacteria,1G5Y8@1117|Cyanobacteria,1HB8Y@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS1_k127_2659623_11	1125863.JAFN01000001_gene1017	1.656e-07	63.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
LZS1_k127_2659623_4	629265.PMA4326_00520	3.985e-46	189.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1Z5BV@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	U	Type IV pilus biogenesis protein PilQ	pilQ	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	-	ko:K02507,ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
LZS1_k127_2659623_9	589865.DaAHT2_2311	1.722e-09	66.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
LZS1_k127_2659623_10	296591.Bpro_0782	3.053e-08	63.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,2VN9T@28216|Betaproteobacteria,4AAVZ@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
LZS1_k127_2659623_2	404589.Anae109_0686	1.767e-55	208.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
LZS1_k127_2659623_7	671143.DAMO_2613	2.187e-39	154.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.1.3.102,3.1.3.104,3.8.1.2	ko:K01560,ko:K07025,ko:K20862	ko00361,ko00625,ko00740,ko01100,ko01110,ko01120,map00361,map00625,map00740,map01100,map01110,map01120	M00125	R00548,R05287,R07280	RC00017,RC00697	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
LZS1_k127_2659623_8	335543.Sfum_2927	2.229e-30	134.0	COG1209@1|root,COG1209@2|Bacteria	335543.Sfum_2927|-	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2659623_5	671143.DAMO_2611	6.235e-45	179.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	6.3.2.29,6.3.2.30	ko:K03802,ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
LZS1_k127_2659623_0	671143.DAMO_2610	1.704e-146	480.0	COG0160@1|root,COG0160@2|Bacteria,2NNRV@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-III	gabT	-	2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36	ko:K03918,ko:K07250,ko:K20428	ko00250,ko00280,ko00410,ko00525,ko00640,ko00650,ko01100,ko01120,ko01130,map00250,map00280,map00410,map00525,map00640,map00650,map01100,map01120,map01130	M00027	R00457,R00908,R01648,R02773,R04188	RC00006,RC00062,RC00160,RC00781	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_2659623_3	335543.Sfum_2924	1.03e-54	206.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,43CWK@68525|delta/epsilon subdivisions,2WSJN@28221|Deltaproteobacteria,2MSI2@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS1_k127_2659623_6	671143.DAMO_2608	1.75e-43	174.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
LZS1_k127_2659623_1	694427.Palpr_2417	1.262e-115	382.0	COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,22WM9@171551|Porphyromonadaceae	976|Bacteroidetes	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
LZS1_k127_2678365_1	278957.ABEA03000201_gene4325	4.873e-55	196.0	COG0444@1|root,COG4608@1|root,COG0444@2|Bacteria,COG4608@2|Bacteria,46U8E@74201|Verrucomicrobia,3KA26@414999|Opitutae	414999|Opitutae	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS1_k127_2678365_0	380703.AHA_3428	3.465e-127	422.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1SKPD@1236|Gammaproteobacteria,1Y442@135624|Aeromonadales	135624|Aeromonadales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS1_k127_2696025_3	27923.ML01833a-PA	1.232e-13	74.0	28K3T@1|root,2QSIA@2759|Eukaryota,3974K@33154|Opisthokonta,3BBX0@33208|Metazoa	2759|Eukaryota	S	Protein of unknown function (DUF2723)	TMEM260	-	-	-	-	-	-	-	-	-	-	-	DUF2723
LZS1_k127_2696025_1	398767.Glov_2314	9.37e-87	308.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
LZS1_k127_2696025_0	269799.Gmet_1853	7.582e-96	345.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,43SVH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS1_k127_2696025_2	269799.Gmet_1854	7.669e-18	97.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,43SYX@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
LZS1_k127_2696025_4	1348657.M622_07040	0.0004501	51.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,2KUD0@206389|Rhodocyclales	206389|Rhodocyclales	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
LZS1_k127_2701935_9	502025.Hoch_3814	6.545e-13	75.0	COG0784@1|root,COG2199@1|root,COG2203@1|root,COG3437@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
LZS1_k127_2701935_1	1089553.Tph_c04910	5.29e-261	830.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,42ET0@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
LZS1_k127_2701935_8	1123288.SOV_2c08930	6.052e-21	108.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,4H3DN@909932|Negativicutes	909932|Negativicutes	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_2701935_3	635013.TherJR_0755	6.797e-135	442.0	COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,25ED1@186801|Clostridia,2609S@186807|Peptococcaceae	186801|Clostridia	T	PFAM PhoH-like protein	-	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
LZS1_k127_2701935_5	1123405.AUMM01000052_gene2622	9.278e-75	264.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,26N8S@186821|Sporolactobacillaceae	91061|Bacilli	H	HemN C-terminal domain	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
LZS1_k127_2701935_7	290397.Adeh_0859	2.679e-34	146.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS1_k127_2701935_6	1122179.KB890414_gene1868	2.708e-70	249.0	COG1159@1|root,COG1159@2|Bacteria,4NES2@976|Bacteroidetes,1INM6@117747|Sphingobacteriia	976|Bacteroidetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
LZS1_k127_2701935_4	1121468.AUBR01000023_gene2754	5.988e-100	349.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,24DP8@186801|Clostridia,42GWZ@68295|Thermoanaerobacterales	186801|Clostridia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
LZS1_k127_2701935_0	330214.NIDE2073	1.442e-275	860.0	COG1389@1|root,COG1389@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
LZS1_k127_2701935_2	330214.NIDE2074	3.893e-172	543.0	COG1697@1|root,COG1697@2|Bacteria	2|Bacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	DUF2220,DUF3322,TP6A_N
LZS1_k127_2733828_0	502025.Hoch_4088	5.36e-64	246.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
LZS1_k127_2733828_1	1125863.JAFN01000001_gene502	6.826e-38	163.0	COG1657@1|root,COG1657@2|Bacteria,1QX5U@1224|Proteobacteria,42ZX1@68525|delta/epsilon subdivisions,2WVF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
LZS1_k127_2756624_0	204669.Acid345_1106	9.843e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,3Y3JH@57723|Acidobacteria,2JI8K@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS1_k127_2799812_6	1179773.BN6_61680	1.284e-14	87.0	COG0641@1|root,COG0641@2|Bacteria,2I2SE@201174|Actinobacteria,4E115@85010|Pseudonocardiales	201174|Actinobacteria	C	radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2799812_1	886293.Sinac_5863	1.133e-41	169.0	COG0603@1|root,COG0603@2|Bacteria,2IZ5W@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
LZS1_k127_2799812_5	1131462.DCF50_p2722	1.753e-15	87.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,260H7@186807|Peptococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
LZS1_k127_2799812_8	641149.HMPREF9016_02126	0.0004008	52.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,2KQXV@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS1_k127_2799812_3	56780.SYN_01692	1.123e-26	125.0	COG0204@1|root,COG0204@2|Bacteria,1P3XM@1224|Proteobacteria	1224|Proteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS1_k127_2799812_0	56780.SYN_01694	1.071e-118	403.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2MQ97@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS1_k127_2799812_4	889378.Spiaf_2285	1.109e-19	96.0	COG0764@1|root,COG0764@2|Bacteria	2|Bacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
LZS1_k127_2799812_2	610130.Closa_0034	2.402e-38	155.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,21YUI@1506553|Lachnoclostridium	186801|Clostridia	IQ	COG COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS1_k127_2799812_7	246194.CHY_1450	1.357e-06	52.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,42ER1@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS1_k127_281434_3	1097668.BYI23_B011560	4.781e-46	190.0	COG0438@1|root,COG0438@2|Bacteria,1N0Z5@1224|Proteobacteria,2VRC8@28216|Betaproteobacteria,1K4W7@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS1_k127_281434_12	1197130.BAFM01000001_gene20	0.0003096	53.0	arCOG08198@1|root,arCOG08198@2157|Archaea,2XVKH@28890|Euryarchaeota,23U6V@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_281434_0	1303518.CCALI_00571	1.634e-88	297.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_281434_9	309801.trd_0841	1.382e-13	83.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi,27XXU@189775|Thermomicrobia	189775|Thermomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS1_k127_281434_7	234267.Acid_3168	3.604e-19	103.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
LZS1_k127_281434_11	304371.MCP_2541	4.365e-11	77.0	COG2244@1|root,arCOG02209@2157|Archaea	304371.MCP_2541|-	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_281434_1	266117.Rxyl_2692	3.56e-60	236.0	COG0438@1|root,COG0438@2|Bacteria,2HUAV@201174|Actinobacteria,4CTZU@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
LZS1_k127_281434_6	1158292.JPOE01000005_gene810	8.367e-22	110.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,2VWGV@28216|Betaproteobacteria,1KPKT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS1_k127_281434_8	1187851.A33M_0669	1.266e-17	98.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
LZS1_k127_281434_10	1500894.JQNN01000001_gene3724	2.053e-12	80.0	COG0399@1|root,COG0399@2|Bacteria,1REP8@1224|Proteobacteria,2VX4S@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS1_k127_281434_4	443143.GM18_0657	2.591e-40	160.0	COG0463@1|root,COG0463@2|Bacteria,1N8QE@1224|Proteobacteria,43BJ3@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K16555	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS1_k127_281434_2	518766.Rmar_1967	1.873e-46	179.0	COG1091@1|root,COG1091@2|Bacteria,4NE3K@976|Bacteroidetes,1FITS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS1_k127_281434_5	596151.DesfrDRAFT_2590	1.19e-36	145.0	COG0279@1|root,COG2605@1|root,COG0279@2|Bacteria,COG2605@2|Bacteria,1QWU7@1224|Proteobacteria,42QI3@68525|delta/epsilon subdivisions,2X8DE@28221|Deltaproteobacteria,2MGSC@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,SIS_2
LZS1_k127_2840200_1	648996.Theam_0610	2.382e-51	200.0	COG0503@1|root,COG0503@2|Bacteria,2G4K7@200783|Aquificae	200783|Aquificae	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
LZS1_k127_2840200_0	1121004.ATVC01000004_gene1476	8.859e-57	211.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,2KQAU@206351|Neisseriales	206351|Neisseriales	K	RNA polymerase sigma factor	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS1_k127_2840200_2	1150399.AQYK01000002_gene2690	6.028e-19	89.0	COG1254@1|root,COG1254@2|Bacteria,2HZJD@201174|Actinobacteria,4FQ1C@85023|Microbacteriaceae	201174|Actinobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
LZS1_k127_2892624_3	575540.Isop_0175	2.329e-26	126.0	COG1807@1|root,COG1807@2|Bacteria,2J1QR@203682|Planctomycetes	203682|Planctomycetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2892624_5	571166.KI421509_gene2729	0.0002482	51.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
LZS1_k127_2892624_0	234267.Acid_4619	2.252e-177	576.0	COG0531@1|root,COG0531@2|Bacteria,3Y2RG@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
LZS1_k127_2892624_2	1408444.JHYC01000010_gene1535	1.174e-37	148.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1JC8J@118969|Legionellales	118969|Legionellales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
LZS1_k127_2892624_1	743525.TSC_c24320	3.95e-63	231.0	COG0223@1|root,COG0223@2|Bacteria,1WI0H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
LZS1_k127_2902020_1	1111479.AXAR01000003_gene1653	1.572e-109	366.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,277WD@186823|Alicyclobacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
LZS1_k127_2902020_2	1396141.BATP01000007_gene5666	4.076e-39	149.0	COG0509@1|root,COG0509@2|Bacteria,46VKU@74201|Verrucomicrobia,2IUJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
LZS1_k127_2902020_0	1173021.ALWA01000012_gene1195	3.487e-188	601.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
LZS1_k127_2904094_0	886293.Sinac_3637	0.0	2098.0	COG0764@1|root,COG3321@1|root,COG0764@2|Bacteria,COG3321@2|Bacteria,2IYQE@203682|Planctomycetes	203682|Planctomycetes	IQ	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA,Ketoacyl-synt_C,ketoacyl-synt
LZS1_k127_2904094_2	443143.GM18_2130	3.293e-128	424.0	COG0332@1|root,COG0332@2|Bacteria,1P9I2@1224|Proteobacteria,42PE7@68525|delta/epsilon subdivisions,2WJZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	fabH-3	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C,Thiolase_N
LZS1_k127_2904094_4	404380.Gbem_2101	1.632e-93	321.0	COG2267@1|root,COG2267@2|Bacteria,1QUW0@1224|Proteobacteria,43CDS@68525|delta/epsilon subdivisions,2X7PQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
LZS1_k127_2904094_1	398767.Glov_2271	2.528e-161	531.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,43S9K@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1,6.2.1.3	ko:K01897,ko:K22319	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	iAF987.Gmet_2229	AMP-binding,AMP-binding_C
LZS1_k127_2904094_3	338966.Ppro_3118	1.626e-121	401.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,42NGH@68525|delta/epsilon subdivisions,2WKS6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-Beta hydroxysteroid dehydrogenase isomerase	-	-	1.1.1.394,1.1.1.412	ko:K21271,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
LZS1_k127_2904094_6	7213.XP_004520320.1	1.578e-19	100.0	COG5479@1|root,2S2KY@2759|Eukaryota,3A1DX@33154|Opisthokonta,3BS3D@33208|Metazoa,3D8FQ@33213|Bilateria,429YY@6656|Arthropoda,3SZE3@50557|Insecta,458TR@7147|Diptera	33208|Metazoa	G	N-acetylmuramoyl-L-alanine amidase activity. It is involved in the biological process described with peptidoglycan catabolic process	PGLYRP1	GO:0000270,GO:0001775,GO:0001817,GO:0001818,GO:0001906,GO:0002218,GO:0002221,GO:0002252,GO:0002253,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002757,GO:0002758,GO:0002764,GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008329,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009595,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0012505,GO:0016019,GO:0016045,GO:0016192,GO:0016787,GO:0016810,GO:0016811,GO:0019730,GO:0023052,GO:0030139,GO:0030141,GO:0030203,GO:0031341,GO:0031343,GO:0031347,GO:0031348,GO:0031349,GO:0031410,GO:0031640,GO:0031974,GO:0031982,GO:0031983,GO:0032101,GO:0032102,GO:0032649,GO:0032689,GO:0032814,GO:0032815,GO:0032823,GO:0032824,GO:0032826,GO:0032827,GO:0032940,GO:0034774,GO:0035580,GO:0035821,GO:0036230,GO:0038023,GO:0038187,GO:0040007,GO:0042119,GO:0042268,GO:0042581,GO:0042742,GO:0042749,GO:0042752,GO:0042834,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043299,GO:0043312,GO:0043900,GO:0043902,GO:0044110,GO:0044116,GO:0044117,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045087,GO:0045088,GO:0045089,GO:0045187,GO:0045321,GO:0045335,GO:0045595,GO:0045596,GO:0045619,GO:0045620,GO:0045824,GO:0045919,GO:0046903,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050727,GO:0050728,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050830,GO:0050865,GO:0050866,GO:0050896,GO:0051093,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051249,GO:0051250,GO:0051606,GO:0051704,GO:0051707,GO:0051709,GO:0051710,GO:0051712,GO:0051714,GO:0051716,GO:0060089,GO:0060205,GO:0061783,GO:0061844,GO:0065007,GO:0070013,GO:0070820,GO:0071682,GO:0071704,GO:0080134,GO:0097013,GO:0097367,GO:0097708,GO:0098542,GO:0098543,GO:0098581,GO:0099503,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1902105,GO:1902106,GO:1903706,GO:1903707,GO:1904724,GO:2000026	-	ko:K01446	-	-	R04112	RC00064,RC00141	ko00000	-	-	-	Amidase_2
LZS1_k127_2904094_7	749222.Nitsa_1546	3.635e-16	92.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2YP49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
LZS1_k127_2904094_5	1184267.A11Q_1982	1.489e-64	237.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,42SIR@68525|delta/epsilon subdivisions,2MT3N@213481|Bdellovibrionales,2WPJY@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
LZS1_k127_2910227_14	1396.DJ87_3530	2.327e-36	143.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,1ZFPU@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0234 family	yitK	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
LZS1_k127_2910227_27	1148.1652245	4.318e-05	56.0	COG2044@1|root,COG2044@2|Bacteria,1GII7@1117|Cyanobacteria,1H6QG@1142|Synechocystis	1117|Cyanobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2910227_4	1121468.AUBR01000045_gene1802	3.68e-117	390.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS1_k127_2910227_15	378806.STAUR_5032	2.577e-33	141.0	COG0637@1|root,COG0637@2|Bacteria,1QX9J@1224|Proteobacteria,43C2S@68525|delta/epsilon subdivisions,2X7DC@28221|Deltaproteobacteria,2Z3FR@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD
LZS1_k127_2910227_3	330214.NIDE3974	6.085e-120	404.0	COG1012@1|root,COG1012@2|Bacteria,3J0YN@40117|Nitrospirae	40117|Nitrospirae	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS1_k127_2910227_6	1499967.BAYZ01000152_gene1402	1.113e-108	370.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
LZS1_k127_2910227_24	1218074.BAXZ01000022_gene4192	2.927e-13	74.0	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,2VTDF@28216|Betaproteobacteria,1K4TZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
LZS1_k127_2910227_26	1502724.FF80_02708	1.794e-12	79.0	COG0454@1|root,COG0456@2|Bacteria,1NARR@1224|Proteobacteria,2UJ98@28211|Alphaproteobacteria,3N7DP@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
LZS1_k127_2910227_17	477974.Daud_2168	9.789e-31	126.0	COG1863@1|root,COG1863@2|Bacteria	2|Bacteria	P	multisubunit Na H antiporter MnhE subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
LZS1_k127_2910227_23	1121413.JMKT01000008_gene1532	1.7e-16	89.0	COG2212@1|root,COG2212@2|Bacteria,1Q6VH@1224|Proteobacteria,42VZI@68525|delta/epsilon subdivisions,2WSAW@28221|Deltaproteobacteria,2MFZR@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	-	-	-	-	-	-	-	-	-	MrpF_PhaF
LZS1_k127_2910227_21	1449126.JQKL01000005_gene848	1.419e-23	108.0	COG1320@1|root,COG1320@2|Bacteria,1VHQ3@1239|Firmicutes,24RQT@186801|Clostridia	186801|Clostridia	P	TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
LZS1_k127_2910227_20	1131269.AQVV01000014_gene189	1.338e-23	111.0	COG2111@1|root,COG2111@2|Bacteria	2|Bacteria	P	Na H antiporter	mnhB	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
LZS1_k127_2910227_18	477974.Daud_2163	2.592e-25	118.0	COG2111@1|root,COG2111@2|Bacteria,1VGF9@1239|Firmicutes	1239|Firmicutes	P	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
LZS1_k127_2910227_22	477974.Daud_2162	2.542e-22	105.0	COG1006@1|root,COG1006@2|Bacteria,1VBKW@1239|Firmicutes,24IY8@186801|Clostridia	186801|Clostridia	P	PFAM NADH-ubiquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
LZS1_k127_2910227_5	477974.Daud_2161	4.087e-110	378.0	COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,24AZH@186801|Clostridia,2678C@186807|Peptococcaceae	186801|Clostridia	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568,ko:K12141	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
LZS1_k127_2910227_1	477974.Daud_2160	6.288e-141	466.0	COG0651@1|root,COG0651@2|Bacteria,1UIA7@1239|Firmicutes,25EF6@186801|Clostridia	186801|Clostridia	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
LZS1_k127_2910227_2	1125863.JAFN01000001_gene2554	2.738e-130	434.0	COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,42MSA@68525|delta/epsilon subdivisions,2WIS1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568,ko:K12137	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
LZS1_k127_2910227_0	697281.Mahau_2356	1.121e-251	809.0	COG1274@1|root,COG1274@2|Bacteria,1TQED@1239|Firmicutes,249NP@186801|Clostridia,42FYF@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
LZS1_k127_2910227_19	1121085.AUCI01000007_gene1178	4.376e-24	110.0	29FE7@1|root,302BX@2|Bacteria,1U6E5@1239|Firmicutes,4HEFF@91061|Bacilli,1ZPE9@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2910227_10	457570.Nther_0145	2.508e-69	265.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,247SS@186801|Clostridia	186801|Clostridia	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
LZS1_k127_2910227_25	66692.ABC0119	3.396e-13	74.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,1ZG9T@1386|Bacillus	91061|Bacilli	S	protein with conserved CXXC pairs	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
LZS1_k127_2910227_7	237368.SCABRO_01638	7.065e-108	364.0	COG2239@1|root,COG2239@2|Bacteria,2IYCZ@203682|Planctomycetes	203682|Planctomycetes	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS1_k127_2910227_13	1121104.AQXH01000001_gene1782	3.555e-44	181.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes	976|Bacteroidetes	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
LZS1_k127_2910227_9	945713.IALB_0513	9.074e-99	331.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
LZS1_k127_2910227_8	309799.DICTH_1250	2.297e-101	338.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS1_k127_2910227_16	443144.GM21_1423	2.473e-32	137.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
LZS1_k127_2910227_11	546274.EIKCOROL_00494	2.097e-58	213.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,2KPQ6@206351|Neisseriales	206351|Neisseriales	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
LZS1_k127_2910227_12	644282.Deba_2111	1.189e-45	171.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
LZS1_k127_2923202_4	1236902.ANAS01000005_gene4771	7.774e-16	85.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4EHPQ@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS1_k127_2923202_1	118163.Ple7327_1594	8.54e-49	186.0	COG2203@1|root,COG3437@1|root,COG3452@1|root,COG5000@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3452@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VIKA@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS1_k127_2923202_5	1150864.MILUP08_46499	1.771e-06	60.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,4DBGR@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
LZS1_k127_2923202_2	1121918.ARWE01000001_gene665	1.229e-39	157.0	COG1765@1|root,COG1765@2|Bacteria,1QF2G@1224|Proteobacteria,42UVN@68525|delta/epsilon subdivisions,2WQVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
LZS1_k127_2923202_3	572480.Arnit_2032	7.644e-17	91.0	COG0607@1|root,COG0607@2|Bacteria,1PEZQ@1224|Proteobacteria,42X5U@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS1_k127_2923202_0	861299.J421_3786	9.014e-159	511.0	COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
LZS1_k127_2937473_2	984262.SGRA_1938	8.722e-13	78.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1IQQ1@117747|Sphingobacteriia	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
LZS1_k127_2937473_0	888055.HMPREF9015_01599	1.798e-94	319.0	COG2877@1|root,COG2877@2|Bacteria,3786I@32066|Fusobacteria	32066|Fusobacteria	H	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
LZS1_k127_2937473_1	697281.Mahau_1553	4.335e-86	290.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,42F21@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
LZS1_k127_2963531_1	1045855.DSC_06305	2.692e-07	53.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S4SZ@1236|Gammaproteobacteria,1X69A@135614|Xanthomonadales	135614|Xanthomonadales	M	lipocalin	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
LZS1_k127_2963531_0	1304885.AUEY01000042_gene3597	1.061e-25	113.0	COG0745@1|root,COG0745@2|Bacteria,1RD9E@1224|Proteobacteria,42PTZ@68525|delta/epsilon subdivisions,2WKZI@28221|Deltaproteobacteria,2MHNV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
LZS1_k127_2972998_2	1313421.JHBV01000041_gene3629	2.598e-124	427.0	COG2304@1|root,COG2304@2|Bacteria,4NK2W@976|Bacteroidetes	976|Bacteroidetes	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VIT,VWA,VWA_3
LZS1_k127_2972998_0	1121920.AUAU01000012_gene2698	1.163e-243	767.0	COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
LZS1_k127_2972998_3	1501230.ET33_07255	1.326e-27	121.0	29FE7@1|root,30YPI@2|Bacteria,1TZAB@1239|Firmicutes,4I8I1@91061|Bacilli,26ZYC@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_2972998_1	1254432.SCE1572_23185	1.11e-161	529.0	2BRHU@1|root,32KGU@2|Bacteria,1Q2UP@1224|Proteobacteria,438H4@68525|delta/epsilon subdivisions,2X3RX@28221|Deltaproteobacteria,2YWYJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_299393_2	1301098.PKB_3165	0.0009664	49.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RN5K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	RND efflux system, outer membrane lipoprotein	oprN	-	-	ko:K18300	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17	-	-	OEP
LZS1_k127_299393_1	1007103.AFHW01000146_gene5073	1.038e-20	104.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,4HG99@91061|Bacilli,26RNQ@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS1_k127_299393_0	401526.TcarDRAFT_0460	1.462e-46	171.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4H22T@909932|Negativicutes	1239|Firmicutes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_3054342_1	370438.PTH_2623	5.314e-73	254.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,260P7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
LZS1_k127_3054342_2	671143.DAMO_2576	1.535e-26	126.0	COG0746@1|root,COG0746@2|Bacteria,2NPYD@2323|unclassified Bacteria	2|Bacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
LZS1_k127_3054342_0	1121920.AUAU01000011_gene223	1.029e-80	283.0	COG0303@1|root,COG0303@2|Bacteria,3Y3F0@57723|Acidobacteria	57723|Acidobacteria	H	TIGRFAM molybdenum cofactor synthesis	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS1_k127_3075138_3	1307436.PBF_02330	2.288e-75	270.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,1ZBFK@1386|Bacillus	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
LZS1_k127_3075138_0	401526.TcarDRAFT_0164	2.177e-80	289.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4H1WJ@909932|Negativicutes	1239|Firmicutes	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
LZS1_k127_3075138_4	640081.Dsui_0628	5.4e-67	240.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,2KU9H@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS1_k127_3075138_1	1122143.AUEG01000002_gene873	1.145e-79	275.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,27FC5@186828|Carnobacteriaceae	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS1_k127_3075138_2	747365.Thena_0240	2.624e-79	278.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,42I94@68295|Thermoanaerobacterales	186801|Clostridia	E	COGs COG0683 ABC-type branched-chain amino acid transport systems periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS1_k127_3082320_0	867903.ThesuDRAFT_01199	4.446e-125	415.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,3WCDU@538999|Clostridiales incertae sedis	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS1_k127_3082320_1	44251.PDUR_15610	1.656e-74	261.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HA7A@91061|Bacilli,26R9K@186822|Paenibacillaceae	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS1_k127_3096653_0	1123073.KB899242_gene1312	2.385e-92	318.0	COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria	1224|Proteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
LZS1_k127_3096653_1	452637.Oter_2162	3.063e-80	284.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
LZS1_k127_309836_3	264732.Moth_1738	7.566e-29	117.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,42I8E@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS1_k127_309836_2	1316936.K678_02208	7.756e-35	141.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,2TSGQ@28211|Alphaproteobacteria,2JS37@204441|Rhodospirillales	204441|Rhodospirillales	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
LZS1_k127_309836_4	378806.STAUR_0754	9.844e-28	122.0	2EIZM@1|root,33CQT@2|Bacteria,1P1YR@1224|Proteobacteria,439UY@68525|delta/epsilon subdivisions,2X58M@28221|Deltaproteobacteria,2Z09N@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_309836_5	1330700.JQNC01000003_gene1084	1.219e-22	111.0	COG0196@1|root,COG0196@2|Bacteria,1WIBE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
LZS1_k127_309836_1	1249627.D779_4177	2.717e-52	198.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales	135613|Chromatiales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
LZS1_k127_309836_6	1379698.RBG1_1C00001G1155	2.318e-15	80.0	COG0858@1|root,COG0858@2|Bacteria,2NPXH@2323|unclassified Bacteria	2|Bacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
LZS1_k127_309836_0	289376.THEYE_A1884	2.189e-190	609.0	COG0532@1|root,COG0532@2|Bacteria,3J0CC@40117|Nitrospirae	40117|Nitrospirae	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
LZS1_k127_3112557_0	1144313.PMI10_02732	1.057e-95	322.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Alpha_L_fucos,Cellulase,RicinB_lectin_2
LZS1_k127_3112557_2	639282.DEFDS_1505	2.156e-29	134.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
LZS1_k127_3112557_1	330214.NIDE1648	1.263e-45	181.0	COG3014@1|root,COG3014@2|Bacteria,3J14B@40117|Nitrospirae	40117|Nitrospirae	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
LZS1_k127_3162636_5	880073.Calab_3274	9.245e-31	130.0	COG0664@1|root,COG0664@2|Bacteria,2NPVK@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS1_k127_3162636_2	243231.GSU1523	9.97e-70	244.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,43T33@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
LZS1_k127_3162636_3	1201293.AKXQ01000011_gene3408	9.48e-51	205.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	iSFV_1184.SFV_0083,iSF_1195.SF0087,iSFxv_1172.SFxv_0091,iS_1188.S0089	Glyco_tran_28_C,Glyco_transf_28
LZS1_k127_3162636_1	643648.Slip_0794	1.025e-76	284.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,42JMA@68298|Syntrophomonadaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
LZS1_k127_3162636_0	1382359.JIAL01000001_gene1975	5.354e-88	311.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria,2JHQF@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS1_k127_3162636_4	682795.AciX8_3882	4.278e-35	135.0	COG0472@1|root,COG0472@2|Bacteria,3Y2ZH@57723|Acidobacteria,2JIGX@204432|Acidobacteriia	204432|Acidobacteriia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
LZS1_k127_3179500_2	1267005.KB911260_gene3481	3.205e-120	395.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,3N6BU@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	DNA photolyase	phrB	GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
LZS1_k127_3179500_9	1124780.ANNU01000020_gene3262	2.68e-31	129.0	COG3040@1|root,COG3040@2|Bacteria,4NNFA@976|Bacteroidetes,47R64@768503|Cytophagia	976|Bacteroidetes	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
LZS1_k127_3179500_7	330214.NIDE0206	8.363e-42	159.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3179500_5	314230.DSM3645_25522	1.209e-76	273.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,2IXEW@203682|Planctomycetes	203682|Planctomycetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
LZS1_k127_3179500_0	926549.KI421517_gene999	4.394e-298	931.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,47MKQ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
LZS1_k127_3179500_4	1297742.A176_06143	4.097e-103	346.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2WNTJ@28221|Deltaproteobacteria,2YZKR@29|Myxococcales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
LZS1_k127_3179500_1	671143.DAMO_2815	4.18e-130	436.0	COG0488@1|root,COG0488@2|Bacteria,2NNPH@2323|unclassified Bacteria	2|Bacteria	S	ABC transporter	MA20_28645	-	3.6.3.29,3.6.3.41	ko:K06022,ko:K06158,ko:K10834	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS1_k127_3179500_10	1192124.LIG30_4445	8.782e-05	48.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2VXXB@28216|Betaproteobacteria,1K9C3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS1_k127_3179500_8	1125863.JAFN01000001_gene3571	2.49e-36	147.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,43AXT@68525|delta/epsilon subdivisions,2X6BZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS1_k127_3179500_3	1165841.SULAR_09719	2.277e-104	357.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2YMQT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Belongs to the peptidase S1C family	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
LZS1_k127_3179500_6	886293.Sinac_1076	2.803e-66	231.0	COG1187@1|root,COG1187@2|Bacteria,2IYUS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS1_k127_3198808_1	1123487.KB892863_gene2012	2.96e-09	69.0	COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,2VWPE@28216|Betaproteobacteria,2KZ6A@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
LZS1_k127_3198808_3	797302.Halru_1025	4.304e-06	54.0	COG2402@1|root,arCOG04502@2157|Archaea,2XXE8@28890|Euryarchaeota,23VKJ@183963|Halobacteria	183963|Halobacteria	V	nucleic acid-binding protein, contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
LZS1_k127_3198808_2	573413.Spirs_2190	2.504e-06	56.0	COG1396@1|root,COG1396@2|Bacteria,2J99Y@203691|Spirochaetes	203691|Spirochaetes	K	Transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
LZS1_k127_3198808_0	546271.Selsp_0267	2.86e-18	91.0	COG4679@1|root,COG4679@2|Bacteria,1VB8K@1239|Firmicutes,4H5UP@909932|Negativicutes	909932|Negativicutes	S	Toxin-antitoxin system, toxin component, RelE family	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
LZS1_k127_3211691_5	861299.J421_4337	9.587e-12	73.0	COG2010@1|root,COG2010@2|Bacteria,1ZUYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS1_k127_3211691_2	1122137.AQXF01000001_gene3064	7.625e-69	242.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2TSXN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	MA20_17625	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
LZS1_k127_3211691_3	1121920.AUAU01000021_gene2521	8.565e-43	176.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
LZS1_k127_3211691_1	395493.BegalDRAFT_2227	2.193e-82	296.0	COG0740@1|root,COG0740@2|Bacteria	2|Bacteria	OU	serine-type endopeptidase activity	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS1_k127_3211691_0	1123070.KB899252_gene972	6.865e-87	294.0	28NXH@1|root,2ZBV3@2|Bacteria,46TF0@74201|Verrucomicrobia,2IUAE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3211691_6	1385519.N801_17210	7.51e-09	70.0	2EVIQ@1|root,33NYW@2|Bacteria,2IIIZ@201174|Actinobacteria	201174|Actinobacteria	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
LZS1_k127_3211691_7	292459.STH595	1.776e-06	60.0	2DR9X@1|root,33AUW@2|Bacteria	2|Bacteria	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
LZS1_k127_3211691_4	176946.XP_007425192.1	1.808e-13	85.0	COG0439@1|root,2QRI6@2759|Eukaryota,38EE1@33154|Opisthokonta,3BFX8@33208|Metazoa,3D1XW@33213|Bilateria,489BC@7711|Chordata,4984C@7742|Vertebrata	33208|Metazoa	I	Carnosine synthase 1	CARNS1	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016881,GO:0016887,GO:0017111,GO:0017144,GO:0019439,GO:0019752,GO:0034641,GO:0035498,GO:0035499,GO:0042398,GO:0043043,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0047730,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	6.3.2.11	ko:K14755	ko00330,ko00340,ko00410,map00330,map00340,map00410	-	R00910,R00912,R01164,R01991,R03286	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	ATP-grasp_4
LZS1_k127_321706_3	1206101.AZXC01000019_gene1511	2.586e-08	66.0	COG0151@1|root,COG0189@1|root,COG0151@2|Bacteria,COG0189@2|Bacteria,2GKTF@201174|Actinobacteria	201174|Actinobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
LZS1_k127_321706_1	1191523.MROS_1829	3.109e-51	201.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlA	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
LZS1_k127_321706_0	378753.KRH_08270	2.373e-121	407.0	COG1087@1|root,COG1087@2|Bacteria,2GMCW@201174|Actinobacteria,1W822@1268|Micrococcaceae	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS1_k127_321706_2	582899.Hden_2857	1.23e-19	101.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2UAVD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3252994_2	452652.KSE_44640	0.0004721	51.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria,2M2JM@2063|Kitasatospora	201174|Actinobacteria	CH	FAD binding domain	-	-	-	ko:K15928	ko01057,ko01130,map01057,map01130	-	R09341,R09343	RC02514,RC02515	ko00000,ko00001	-	-	-	FAD_binding_3
LZS1_k127_3252994_0	398767.Glov_3125	3.157e-99	340.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS1_k127_3252994_1	880073.Calab_2684	2.525e-21	96.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
LZS1_k127_3267115_1	388413.ALPR1_15134	0.0006108	48.0	COG1555@1|root,COG1555@2|Bacteria,4NVH1@976|Bacteroidetes,47XU1@768503|Cytophagia	976|Bacteroidetes	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3267115_0	330214.NIDE3591	1.418e-90	319.0	COG0744@1|root,COG0744@2|Bacteria,3J1FP@40117|Nitrospirae	40117|Nitrospirae	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
LZS1_k127_3292090_1	351160.RCIX1538	2.718e-133	444.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,2N9CA@224756|Methanomicrobia	224756|Methanomicrobia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
LZS1_k127_3292090_2	443254.Marpi_0548	1.31e-87	319.0	COG0075@1|root,COG0075@2|Bacteria,2GCGI@200918|Thermotogae	200918|Thermotogae	E	PFAM aminotransferase class V	-	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS1_k127_3292090_0	429009.Adeg_0493	5.506e-244	784.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS1_k127_3292090_3	926560.KE387023_gene3830	1.639e-64	227.0	COG0740@1|root,COG0740@2|Bacteria,1WI6Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS1_k127_3292090_4	1384049.CD29_09870	4.229e-23	109.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,3IWJM@400634|Lysinibacillus	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
LZS1_k127_3312464_12	96561.Dole_0941	4.192e-82	278.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2WJ32@28221|Deltaproteobacteria,2MIH7@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS1_k127_3312464_3	96561.Dole_0942	4.648e-205	655.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,42PKG@68525|delta/epsilon subdivisions,2WKPG@28221|Deltaproteobacteria,2MIZJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
LZS1_k127_3312464_5	1121405.dsmv_3559	7.283e-147	489.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,42P23@68525|delta/epsilon subdivisions,2WK75@28221|Deltaproteobacteria,2MIZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
LZS1_k127_3312464_6	1121405.dsmv_3558	8.019e-145	466.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,43BKS@68525|delta/epsilon subdivisions,2X6YW@28221|Deltaproteobacteria,2MIBW@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
LZS1_k127_3312464_1	502025.Hoch_2603	1.32e-224	712.0	COG0167@1|root,COG0479@1|root,COG0167@2|Bacteria,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.1.1,1.3.1.2,1.97.1.9	ko:K00207,ko:K12527,ko:K17723	ko00240,ko00410,ko00450,ko00770,ko00983,ko01100,map00240,map00410,map00450,map00770,map00983,map01100	M00046	R00977,R00978,R01414,R01415,R07229,R08226,R11026	RC00072,RC00123,RC02245,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	ATC_hydrolase,CCG,DHO_dh,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_20,Fer4_8,Pyr_redox_2
LZS1_k127_3312464_18	1122604.JONR01000001_gene1735	1.001e-25	111.0	2FAF9@1|root,342PH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3312464_10	502025.Hoch_3413	4.795e-108	357.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2WP4Z@28221|Deltaproteobacteria,2YU7V@29|Myxococcales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
LZS1_k127_3312464_4	502025.Hoch_6670	1.456e-155	505.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,42MTD@68525|delta/epsilon subdivisions,2WMRP@28221|Deltaproteobacteria,2Z0YS@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS1_k127_3312464_9	563192.HMPREF0179_02738	4.23e-116	401.0	COG0402@1|root,COG0402@2|Bacteria,1Q1P7@1224|Proteobacteria,42U3F@68525|delta/epsilon subdivisions,2WR49@28221|Deltaproteobacteria,2MF5Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Amidohydrolase family	ssnA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS1_k127_3312464_0	1167006.UWK_01309	8.79e-263	840.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
LZS1_k127_3312464_2	1499967.BAYZ01000188_gene3892	1.646e-209	667.0	COG0031@1|root,COG0031@2|Bacteria,2NNZI@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47,6.2.1.30	ko:K01738,ko:K01912	ko00270,ko00360,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko05111,map00270,map00360,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map05111	M00021	R00897,R02539,R03601,R04859	RC00004,RC00014,RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS1_k127_3312464_7	1167006.UWK_01323	2.212e-121	402.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS1_k127_3312464_17	404589.Anae109_0899	2.482e-49	184.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3312464_11	1158338.JNLJ01000001_gene939	2.757e-102	355.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS1_k127_3312464_14	338969.Rfer_0258	1.565e-53	205.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,2WEWP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS1_k127_3312464_19	402881.Plav_3368	1.83e-12	75.0	COG3677@1|root,COG3677@2|Bacteria,1R999@1224|Proteobacteria,2UD3G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
LZS1_k127_3312464_21	880073.Calab_1263	1.106e-07	62.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS1_k127_3312464_16	269799.Gmet_1869	4.177e-52	198.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS1_k127_3312464_8	1125863.JAFN01000001_gene1528	1.894e-119	412.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS1_k127_3312464_15	1232410.KI421428_gene1053	2.147e-53	207.0	COG4191@1|root,COG4191@2|Bacteria,1N2VE@1224|Proteobacteria,43AY6@68525|delta/epsilon subdivisions,2X6CJ@28221|Deltaproteobacteria,43T05@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS1_k127_3312464_20	243231.GSU3226	2.202e-09	66.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,42YEH@68525|delta/epsilon subdivisions,2WU0R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS1_k127_3312464_13	756499.Desde_2801	1.843e-66	239.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,2611X@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS1_k127_3312464_22	1120999.JONM01000001_gene1187	1.035e-06	58.0	2E49J@1|root,32Z5A@2|Bacteria,1NFEB@1224|Proteobacteria,2VX10@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3321247_6	401053.AciPR4_0264	8.155e-39	149.0	COG0272@1|root,COG0272@2|Bacteria,3Y2UR@57723|Acidobacteria,2JHN1@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS1_k127_3321247_2	1009370.ALO_02421	1e-93	332.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H34D@909932|Negativicutes	909932|Negativicutes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
LZS1_k127_3321247_8	945543.VIBR0546_02645	1.24e-11	73.0	2A3UB@1|root,30SC9@2|Bacteria,1PAV1@1224|Proteobacteria,1SWA6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4279
LZS1_k127_3321247_5	398527.Bphyt_0330	2.442e-60	225.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VJ7N@28216|Betaproteobacteria,1K34X@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
LZS1_k127_3321247_1	1089552.KI911559_gene2515	1.954e-97	328.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	4.1.99.22	ko:K03639,ko:K15045	ko00790,ko01100,ko04122,ko05164,map00790,map01100,map04122,map05164	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
LZS1_k127_3321247_4	1089552.KI911559_gene2517	6.871e-85	302.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2TTS5@28211|Alphaproteobacteria,2JRCB@204441|Rhodospirillales	204441|Rhodospirillales	S	Elongator protein 3, MiaB family, Radical SAM	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS1_k127_3321247_3	1089552.KI911559_gene2518	1.727e-92	327.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS1_k127_3321247_0	1089552.KI911559_gene2519	3.976e-123	406.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2TTS5@28211|Alphaproteobacteria,2JRCB@204441|Rhodospirillales	204441|Rhodospirillales	S	Elongator protein 3, MiaB family, Radical SAM	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS1_k127_3321351_10	398767.Glov_0642	1.534e-08	68.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
LZS1_k127_3321351_8	880073.Calab_3299	7.926e-12	80.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
LZS1_k127_3321351_0	1278073.MYSTI_00649	5.672e-149	500.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria,2YTZK@29|Myxococcales	28221|Deltaproteobacteria	CE	Peptidase family M1 domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,HEAT_2,Peptidase_M1
LZS1_k127_3321351_1	697281.Mahau_1317	5.909e-134	441.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS1_k127_3321351_5	1128398.Curi_c16290	1.739e-53	198.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,2691S@186813|unclassified Clostridiales	186801|Clostridia	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
LZS1_k127_3321351_7	243159.AFE_1909	1.419e-27	113.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,2ND6R@225057|Acidithiobacillales	225057|Acidithiobacillales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS1_k127_3321351_4	1392493.JIAB01000001_gene673	5.303e-76	265.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,27IXU@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS1_k127_3321351_3	1121472.AQWN01000002_gene2329	2.208e-91	311.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
LZS1_k127_3321351_11	1384066.JAGT01000001_gene141	6.98e-06	50.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3WKID@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
LZS1_k127_3321351_9	1273103.NM10_10365	3.296e-11	72.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,4H5EU@909932|Negativicutes	909932|Negativicutes	S	acr, cog1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
LZS1_k127_3321351_2	932678.THERU_02220	1.761e-102	342.0	COG0463@1|root,COG0463@2|Bacteria,2G3VF@200783|Aquificae	200783|Aquificae	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_3321351_6	886293.Sinac_7080	2.744e-42	160.0	COG3832@1|root,COG3832@2|Bacteria,2J0ET@203682|Planctomycetes	203682|Planctomycetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
LZS1_k127_3323211_1	266117.Rxyl_0229	1.372e-101	338.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CP86@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS1_k127_3323211_3	6500.XP_005093392.1	4.415e-93	327.0	COG0320@1|root,KOG2672@2759|Eukaryota,38EBV@33154|Opisthokonta,3BEE6@33208|Metazoa,3CRPM@33213|Bilateria	33208|Metazoa	H	GO:0070283	LIAS	GO:0001838,GO:0001841,GO:0001843,GO:0002009,GO:0002237,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006979,GO:0007275,GO:0007399,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009790,GO:0009792,GO:0009888,GO:0009987,GO:0010033,GO:0010467,GO:0014020,GO:0016053,GO:0016331,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0021915,GO:0031974,GO:0032496,GO:0032501,GO:0032502,GO:0032787,GO:0033993,GO:0034641,GO:0035148,GO:0035239,GO:0035295,GO:0036211,GO:0042221,GO:0043009,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0048598,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0050896,GO:0051186,GO:0051188,GO:0051604,GO:0051704,GO:0051707,GO:0060429,GO:0060562,GO:0060606,GO:0070013,GO:0070283,GO:0071704,GO:0072175,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901700	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
LZS1_k127_3323211_2	243231.GSU2654	1.626e-96	328.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,43UJJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
LZS1_k127_3323211_0	644966.Tmar_1672	3.866e-124	407.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,249UD@186801|Clostridia	186801|Clostridia	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS1_k127_3352268_2	1254432.SCE1572_09510	5.376e-61	213.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
LZS1_k127_3352268_3	448385.sce1438	2.026e-49	180.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
LZS1_k127_3352268_1	396588.Tgr7_1960	2.729e-71	259.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1WYZZ@135613|Chromatiales	135613|Chromatiales	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
LZS1_k127_3352268_4	867903.ThesuDRAFT_00783	2.057e-28	120.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
LZS1_k127_3352268_0	666685.R2APBS1_2903	4.935e-88	307.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1SN7Y@1236|Gammaproteobacteria,1X4R2@135614|Xanthomonadales	135614|Xanthomonadales	H	molybdopterin biosynthesis	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS1_k127_3352268_5	1463854.JOHT01000010_gene144	2.419e-10	62.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria	201174|Actinobacteria	H	Molybdenum cofactor synthesis	mog	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaE
LZS1_k127_3356540_0	404380.Gbem_0302	1.757e-185	610.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGIPQ	Acyltransferase	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
LZS1_k127_3356540_1	395494.Galf_2633	6.447e-19	96.0	COG2755@1|root,COG2755@2|Bacteria,1NTK7@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	wssF	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3384555_0	234267.Acid_7180	4.037e-101	359.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria	57723|Acidobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
LZS1_k127_3384555_1	1297742.A176_05066	8.111e-91	324.0	COG4531@1|root,COG4531@2|Bacteria,1REHQ@1224|Proteobacteria,42TZ1@68525|delta/epsilon subdivisions,2WQ6N@28221|Deltaproteobacteria,2YY91@29|Myxococcales	28221|Deltaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3384555_2	1125863.JAFN01000001_gene2793	7.676e-77	270.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS1_k127_3394800_0	500153.JOEK01000005_gene2117	1.424e-100	332.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS1_k127_3394800_3	390874.Tpet_1288	2.407e-48	177.0	COG0049@1|root,COG0049@2|Bacteria,2GCUI@200918|Thermotogae	200918|Thermotogae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
LZS1_k127_3394800_1	555079.Toce_0114	6.485e-56	205.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,42GED@68295|Thermoanaerobacterales	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
LZS1_k127_3394800_2	331635.G5S_1065	2.444e-51	185.0	COG0086@1|root,COG0086@2|Bacteria,2JFCX@204428|Chlamydiae	204428|Chlamydiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
LZS1_k127_3402580_1	525903.Taci_1196	2.738e-143	469.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3T9XI@508458|Synergistetes	508458|Synergistetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
LZS1_k127_3402580_10	1120956.JHZK01000022_gene1568	2.43e-17	91.0	COG0671@1|root,COG0671@2|Bacteria,1PX74@1224|Proteobacteria,2TUV9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
LZS1_k127_3402580_9	929712.KI912613_gene3614	9.381e-32	139.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CQCJ@84995|Rubrobacteria	84995|Rubrobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
LZS1_k127_3402580_6	545695.TREAZ_2049	8.725e-48	189.0	COG1183@1|root,COG1183@2|Bacteria,2J8B5@203691|Spirochaetes	203691|Spirochaetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
LZS1_k127_3402580_8	1121456.ATVA01000013_gene1187	5.742e-36	145.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,42QDS@68525|delta/epsilon subdivisions,2WMQ3@28221|Deltaproteobacteria,2M7ZF@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
LZS1_k127_3402580_5	1265313.HRUBRA_01076	1.881e-54	194.0	COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,1S3V3@1236|Gammaproteobacteria,1JB8J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	FJ	MafB19-like deaminase	cdd	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
LZS1_k127_3402580_0	945713.IALB_1601	2.9e-174	562.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	sulP	GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015810,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	iSbBS512_1146.SbBS512_E1370	STAS,Sulfate_transp
LZS1_k127_3402580_2	941824.TCEL_01822	2.431e-107	358.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,36DRX@31979|Clostridiaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
LZS1_k127_3402580_11	1120983.KB894573_gene162	3.435e-05	52.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2TQJU@28211|Alphaproteobacteria,1JPSF@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
LZS1_k127_3402580_7	1244869.H261_13469	5.476e-38	150.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2U74E@28211|Alphaproteobacteria,2JS6D@204441|Rhodospirillales	204441|Rhodospirillales	E	GDSL-like Lipase/Acylhydrolase	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
LZS1_k127_3402580_4	1033802.SSPSH_001785	4.713e-61	218.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	(ABC) transporter	ybbA	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_3402580_3	765912.Thimo_1564	9.181e-70	269.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1WX8V@135613|Chromatiales	135613|Chromatiales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
LZS1_k127_3440384_3	634956.Geoth_3487	1.406e-06	57.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,4HEI3@91061|Bacilli,1WFJD@129337|Geobacillus	91061|Bacilli	O	XdhC and CoxI family	pucA	-	1.17.1.4	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	XdhC_C,XdhC_CoxI
LZS1_k127_3440384_0	330214.NIDE0521	2.054e-47	182.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
LZS1_k127_3440384_1	1303518.CCALI_01253	1.992e-39	162.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
LZS1_k127_3440384_2	1128421.JAGA01000002_gene1365	1.452e-28	132.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS1_k127_3448773_2	1089549.AZUQ01000001_gene665	2.186e-49	202.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4EY9U@85014|Glycomycetales	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS1_k127_3448773_1	370438.PTH_1781	1.983e-52	212.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS1_k127_3448773_0	871968.DESME_11900	3.868e-53	213.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS1_k127_3486883_0	269799.Gmet_0078	1.045e-84	290.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,42M77@68525|delta/epsilon subdivisions,2WM41@28221|Deltaproteobacteria,43SS1@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS1_k127_3486883_3	945713.IALB_2055	1.862e-24	123.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
LZS1_k127_3486883_5	130081.XP_005705574.1	4.503e-07	66.0	COG0457@1|root,KOG0548@2759|Eukaryota	2759|Eukaryota	J	positive regulation of catalytic activity in other organism involved in symbiotic interaction	STI1	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0004857,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005794,GO:0005829,GO:0006457,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0030234,GO:0030544,GO:0031072,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042030,GO:0042886,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0050790,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051879,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072594,GO:0072655,GO:0097159,GO:0098772,GO:0101031,GO:1901363	-	ko:K09553	ko05020,map05020	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_8
LZS1_k127_3486883_4	517418.Ctha_2595	8.201e-20	108.0	COG2304@1|root,COG2304@2|Bacteria,1FDZC@1090|Chlorobi	1090|Chlorobi	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
LZS1_k127_3486883_1	880073.Calab_2467	4.417e-42	182.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
LZS1_k127_3486883_2	929703.KE386491_gene854	6.974e-34	147.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,47KTK@768503|Cytophagia	976|Bacteroidetes	S	PFAM ATPase associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS1_k127_3488667_1	1303518.CCALI_02390	1.111e-74	260.0	COG0079@1|root,COG0079@2|Bacteria	2|Bacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_3488667_2	1121422.AUMW01000001_gene2463	8.386e-48	188.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,261QH@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
LZS1_k127_3488667_4	1283299.AUKG01000001_gene3035	4.724e-29	129.0	COG0204@1|root,COG0240@1|root,COG0204@2|Bacteria,COG0240@2|Bacteria,2GJ6V@201174|Actinobacteria,4CP70@84995|Rubrobacteria	84995|Rubrobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
LZS1_k127_3488667_3	1316936.K678_11101	2.913e-41	168.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,2JR06@204441|Rhodospirillales	204441|Rhodospirillales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
LZS1_k127_3488667_6	326427.Cagg_2400	0.0004172	53.0	COG0457@1|root,COG0457@2|Bacteria,2GAB4@200795|Chloroflexi,374UY@32061|Chloroflexia	32061|Chloroflexia	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2
LZS1_k127_3488667_0	1123393.KB891330_gene909	2.706e-119	401.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,1KRG7@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
LZS1_k127_3488667_5	1242864.D187_006163	5.921e-05	54.0	COG2161@1|root,COG2161@2|Bacteria,1Q1K4@1224|Proteobacteria,43EY3@68525|delta/epsilon subdivisions,2XA1E@28221|Deltaproteobacteria,2Z1CV@29|Myxococcales	28221|Deltaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
LZS1_k127_3512655_5	358220.C380_06400	4.065e-05	56.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,4ACNP@80864|Comamonadaceae	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
LZS1_k127_3512655_4	562970.Btus_1957	1.392e-23	102.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli	91061|Bacilli	K	Cold-Shock Protein	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS1_k127_3512655_2	292459.STH1876	3.38e-35	143.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia	186801|Clostridia	I	thioesterase	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS1_k127_3512655_1	391623.TERMP_01733	1.459e-62	229.0	COG0388@1|root,arCOG00062@2157|Archaea,2XVVK@28890|Euryarchaeota,242PM@183968|Thermococci	183968|Thermococci	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
LZS1_k127_3512655_3	485913.Krac_10271	8.085e-33	138.0	COG0500@1|root,COG2226@2|Bacteria,2GA94@200795|Chloroflexi	200795|Chloroflexi	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS1_k127_3512655_0	1385517.N800_06240	6.845e-84	313.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1X5E6@135614|Xanthomonadales	135614|Xanthomonadales	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS1_k127_3515598_0	269796.Rru_A0773	7.579e-06	58.0	COG2710@1|root,COG2710@2|Bacteria,1R5QU@1224|Proteobacteria,2U2SP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	PFAM oxidoreductase nitrogenase, component 1	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
LZS1_k127_3581363_0	1121346.KB899808_gene3427	1.162e-92	340.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,26R07@186822|Paenibacillaceae	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
LZS1_k127_3581363_1	1128421.JAGA01000002_gene480	1.558e-46	190.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
LZS1_k127_3581363_2	1123389.ATXJ01000003_gene253	6.556e-46	174.0	COG0572@1|root,COG0572@2|Bacteria,1WIG1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
LZS1_k127_3581363_3	760192.Halhy_1033	9.785e-37	157.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	PMT_2
LZS1_k127_3596700_0	1071679.BG57_02395	1.046e-65	234.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2VRIW@28216|Betaproteobacteria,1K5NR@119060|Burkholderiaceae	28216|Betaproteobacteria	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
LZS1_k127_3596700_1	497964.CfE428DRAFT_5269	3.048e-36	151.0	COG1363@1|root,COG1363@2|Bacteria,46T0I@74201|Verrucomicrobia	74201|Verrucomicrobia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
LZS1_k127_3596700_2	706587.Desti_0562	3.862e-33	147.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQU0@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS1_k127_3605416_8	1244869.H261_13925	3.516e-48	183.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2U0P8@28211|Alphaproteobacteria,2JPNG@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_3605416_6	1121272.KB903253_gene6928	9.226e-89	312.0	COG2303@1|root,COG2303@2|Bacteria,2IHDE@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C
LZS1_k127_3605416_0	269799.Gmet_1424	9.573e-198	646.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
LZS1_k127_3605416_5	552811.Dehly_0470	1.177e-91	329.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi,34CP3@301297|Dehalococcoidia	301297|Dehalococcoidia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
LZS1_k127_3605416_7	264462.Bd0660	9.603e-76	274.0	2BI6Q@1|root,32CBY@2|Bacteria,1MYDT@1224|Proteobacteria,42T3X@68525|delta/epsilon subdivisions,2MTZ4@213481|Bdellovibrionales,2WPSM@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Protein of unknown function (DUF2914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2914
LZS1_k127_3605416_10	246197.MXAN_3771	4.283e-36	147.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,42WF1@68525|delta/epsilon subdivisions,2WS1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
LZS1_k127_3605416_3	765952.PUV_07350	3.927e-98	351.0	COG0793@1|root,COG0793@2|Bacteria,2JFSF@204428|Chlamydiae	204428|Chlamydiae	M	Belongs to the chlamydial CPn_1016 CT_858 TC_0248 family	CP_0837	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
LZS1_k127_3605416_9	673860.AciM339_0766	1.991e-41	159.0	COG1014@1|root,arCOG01603@2157|Archaea,2XVFR@28890|Euryarchaeota,3F2RB@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.7.1,1.2.7.7	ko:K00172,ko:K00189	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
LZS1_k127_3605416_11	70601.3257087	2.002e-18	89.0	COG1144@1|root,arCOG01605@2157|Archaea,2XY2F@28890|Euryarchaeota,245HQ@183968|Thermococci	183968|Thermococci	C	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity	vorD	-	1.2.7.7	ko:K00188	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	Fer4
LZS1_k127_3605416_2	1121405.dsmv_1953	1.121e-120	402.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
LZS1_k127_3605416_4	1125863.JAFN01000001_gene2833	1.96e-93	329.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
LZS1_k127_3605416_1	485915.Dret_1750	4.753e-162	533.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
LZS1_k127_3608228_1	1121468.AUBR01000036_gene1296	7.386e-125	415.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,42EVH@68295|Thermoanaerobacterales	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
LZS1_k127_3608228_2	477974.Daud_0599	1.882e-57	216.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,260T7@186807|Peptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
LZS1_k127_3608228_5	204773.HEAR2409	0.0001538	53.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,4730Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
LZS1_k127_3608228_0	908612.HMPREF9720_2610	2.491e-125	436.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,2FMHE@200643|Bacteroidia,22UTN@171550|Rikenellaceae	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
LZS1_k127_3608228_3	1232410.KI421421_gene3883	2.695e-54	207.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria,43UI6@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS1_k127_366428_0	118168.MC7420_3051	6.776e-38	164.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_366428_1	1463901.JOIY01000030_gene268	2e-10	70.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
LZS1_k127_3678130_2	404380.Gbem_1080	6.895e-45	188.0	COG3979@1|root,COG4447@1|root,COG3979@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	chiA	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.2.1.132,3.2.1.14,3.2.1.17	ko:K01183,ko:K01233,ko:K13381	ko00520,ko01100,map00520,map01100	-	R01206,R02334,R02833	RC00467	ko00000,ko00001,ko01000	-	CBM15,GH18	-	CBM_5_12,Glyco_hydro_18,LPMO_10,fn3
LZS1_k127_3678130_0	448385.sce1586	3.293e-99	359.0	2BRF1@1|root,32KDW@2|Bacteria,1Q2SY@1224|Proteobacteria,438ER@68525|delta/epsilon subdivisions,2X3PP@28221|Deltaproteobacteria,2YWSS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3678130_1	1047013.AQSP01000128_gene418	8.291e-48	189.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
LZS1_k127_3678130_3	1265313.HRUBRA_00543	3.319e-06	56.0	COG0457@1|root,COG4976@1|root,COG0457@2|Bacteria,COG4976@2|Bacteria,1RAIT@1224|Proteobacteria,1S6MW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	methyltransferase	yrrB	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31,TPR_1,TPR_16,TPR_2,TPR_4,TPR_7,TPR_8
LZS1_k127_3694762_4	1242864.D187_005156	1.425e-17	86.0	COG0467@1|root,COG0467@2|Bacteria,1NM7E@1224|Proteobacteria,42SM2@68525|delta/epsilon subdivisions,2WPEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
LZS1_k127_3694762_2	211165.AJLN01000116_gene3217	1.537e-61	232.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,1G35U@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_3694762_6	1313304.CALK_0269	6.199e-05	55.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_2,Glyco_hydro_66,Pec_lyase_C,RicinB_lectin_2,Ricin_B_lectin,TonB_C,fn3
LZS1_k127_3694762_5	1442599.JAAN01000019_gene2401	9.761e-11	68.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1X6SD@135614|Xanthomonadales	135614|Xanthomonadales	U	Biopolymer	exbD4	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS1_k127_3694762_3	682795.AciX8_4402	1.068e-30	129.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria,2JI9T@204432|Acidobacteriia	204432|Acidobacteriia	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
LZS1_k127_3694762_0	1254432.SCE1572_30505	1.736e-91	311.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2Z39N@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
LZS1_k127_3694762_1	1122599.AUGR01000009_gene2448	3.51e-64	228.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XNUF@135619|Oceanospirillales	135619|Oceanospirillales	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
LZS1_k127_3698503_0	68223.JNZY01000015_gene2483	5.065e-07	63.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_3703957_5	575540.Isop_2332	2.951e-27	122.0	COG3356@1|root,COG3356@2|Bacteria,2IXX5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
LZS1_k127_3703957_4	358823.DF19_00570	4.383e-28	117.0	COG0745@1|root,COG0745@2|Bacteria,2IQWH@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_3703957_7	1128427.KB904821_gene1281	8.976e-07	61.0	COG0642@1|root,COG2199@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1H8FM@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS1_k127_3703957_3	1242864.D187_008066	8.303e-49	179.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2WP23@28221|Deltaproteobacteria,2Z0GF@29|Myxococcales	28221|Deltaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
LZS1_k127_3703957_1	378806.STAUR_5402	8.027e-199	632.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS1_k127_3703957_6	290397.Adeh_2115	7.858e-23	111.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS1_k127_3703957_0	523791.Kkor_2113	0.0	1053.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1XHCH@135619|Oceanospirillales	135619|Oceanospirillales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS1_k127_3703957_2	706587.Desti_5503	5.504e-56	219.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Spermine spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
LZS1_k127_3715157_2	926566.Terro_0850	2.673e-27	124.0	COG1529@1|root,COG1529@2|Bacteria,3Y6BF@57723|Acidobacteria	57723|Acidobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS1_k127_3715157_0	298386.PBPRB0863	1.649e-46	178.0	COG2010@1|root,COG2010@2|Bacteria,1RCYF@1224|Proteobacteria,1SEBP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS1_k127_3715157_3	42345.XP_008798075.1	0.0005807	52.0	COG1230@1|root,KOG1484@2759|Eukaryota,37SDQ@33090|Viridiplantae,3GBV2@35493|Streptophyta,3KQY5@4447|Liliopsida	35493|Streptophyta	P	Cation efflux family	-	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0012505,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0032879,GO:0034220,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046873,GO:0046915,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061088,GO:0065007,GO:0065008,GO:0070838,GO:0071577,GO:0071578,GO:0072509,GO:0072511,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098739,GO:0099587	-	ko:K08900,ko:K14692	-	-	-	-	ko00000,ko02000,ko03029	2.A.4.4.3,2.A.4.4.5	-	-	Cation_efflux
LZS1_k127_3715157_1	497964.CfE428DRAFT_0840	1.651e-41	160.0	COG3011@1|root,COG3011@2|Bacteria,46U84@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
LZS1_k127_3716953_0	1120973.AQXL01000135_gene1394	6.871e-140	455.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,27884@186823|Alicyclobacillaceae	91061|Bacilli	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
LZS1_k127_3758366_5	1216007.AOPM01000024_gene2983	7.445e-07	57.0	COG3018@1|root,COG3018@2|Bacteria,1RIA2@1224|Proteobacteria,1S4BX@1236|Gammaproteobacteria,2Q2F9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	N	protein conserved in bacteria	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	LPP20
LZS1_k127_3758366_4	880073.Calab_3761	4.529e-10	70.0	COG1462@1|root,COG1462@2|Bacteria,2NQ4P@2323|unclassified Bacteria	2|Bacteria	M	Curli production assembly transport component CsgG	csgG	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF4384,FlgT_C,PG_binding_1
LZS1_k127_3758366_2	1216932.CM240_1942	2.593e-28	124.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,36ESG@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_3758366_0	794903.OPIT5_19775	3.895e-48	177.0	COG1510@1|root,COG1510@2|Bacteria,46VGF@74201|Verrucomicrobia,3K99X@414999|Opitutae	414999|Opitutae	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3758366_1	1123401.JHYQ01000020_gene978	3.874e-32	137.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,45ZXK@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS1_k127_3769687_0	345219.Bcoa_1247	1.01e-130	432.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,1ZAVH@1386|Bacillus	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
LZS1_k127_3769687_1	671143.DAMO_0507	2.965e-116	383.0	COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
LZS1_k127_3769687_2	509190.Cseg_0552	2.885e-15	81.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,2KGBD@204458|Caulobacterales	204458|Caulobacterales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
LZS1_k127_3772569_6	1265505.ATUG01000001_gene4342	1.839e-21	106.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,42MX3@68525|delta/epsilon subdivisions,2WKI4@28221|Deltaproteobacteria,2MI7Y@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
LZS1_k127_3772569_7	1380346.JNIH01000035_gene343	2.913e-09	62.0	2E3SC@1|root,32YPX@2|Bacteria,2GQRK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
LZS1_k127_3772569_1	460265.Mnod_1405	3.551e-109	362.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TR5S@28211|Alphaproteobacteria,1JYZX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	NAD dependent epimerase/dehydratase family	ydfG	-	1.1.1.276,1.1.1.381	ko:K05886,ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
LZS1_k127_3772569_3	1280390.CBQR020000086_gene1885	2.695e-92	313.0	COG0451@1|root,COG0451@2|Bacteria,1TR3K@1239|Firmicutes,4HD3P@91061|Bacilli,26V3Z@186822|Paenibacillaceae	91061|Bacilli	GM	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
LZS1_k127_3772569_4	983917.RGE_38700	9.813e-51	183.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
LZS1_k127_3772569_5	1162668.LFE_1798	1.096e-34	147.0	COG1225@1|root,COG1225@2|Bacteria,3J12D@40117|Nitrospirae	40117|Nitrospirae	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS1_k127_3772569_2	1144275.COCOR_04182	8.324e-100	361.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2YU3H@29|Myxococcales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
LZS1_k127_3772569_0	509635.N824_19125	2.911e-256	809.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes,1INRQ@117747|Sphingobacteriia	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
LZS1_k127_3773625_20	688245.CtCNB1_2533	3.773e-07	60.0	COG2267@1|root,COG2267@2|Bacteria,1N0W6@1224|Proteobacteria,2VSJ4@28216|Betaproteobacteria,4AHZF@80864|Comamonadaceae	28216|Betaproteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS1_k127_3773625_3	244447.XP_008333012.1	2.881e-129	442.0	COG0339@1|root,KOG2089@2759|Eukaryota,38SFI@33154|Opisthokonta,3B98M@33208|Metazoa,3CT8Z@33213|Bilateria,47ZCM@7711|Chordata,492KW@7742|Vertebrata,49YGV@7898|Actinopterygii	33208|Metazoa	O	Thimet oligopeptidase	THOP1	GO:0000209,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006464,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0016567,GO:0016787,GO:0019538,GO:0023052,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032446,GO:0033218,GO:0034641,GO:0035556,GO:0036211,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0070013,GO:0070647,GO:0071704,GO:0140096,GO:1901564	3.4.24.15,3.4.24.16	ko:K01392,ko:K01393	ko04614,ko05143,map04614,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M3
LZS1_k127_3773625_13	1097668.BYI23_A002700	5.085e-34	144.0	COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria,2VIKI@28216|Betaproteobacteria,1K0I9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS1_k127_3773625_2	290397.Adeh_2048	2.902e-159	529.0	COG1449@1|root,COG1449@2|Bacteria,1PUYM@1224|Proteobacteria,42MQP@68525|delta/epsilon subdivisions,2WKP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
LZS1_k127_3773625_4	383372.Rcas_0031	6.91e-117	400.0	COG2114@1|root,COG2114@2|Bacteria,2GBUH@200795|Chloroflexi,376W9@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
LZS1_k127_3773625_7	1408473.JHXO01000005_gene1472	2.421e-59	214.0	COG2834@1|root,COG2834@2|Bacteria,4NIT5@976|Bacteroidetes,2FSCB@200643|Bacteroidia	976|Bacteroidetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
LZS1_k127_3773625_9	1191523.MROS_1666	2.765e-56	212.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	VPA0559	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
LZS1_k127_3773625_6	1235457.C404_26035	3.183e-72	250.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VR8F@28216|Betaproteobacteria,1K7NT@119060|Burkholderiaceae	28216|Betaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_3773625_10	1235457.C404_26045	9.462e-49	190.0	2C2F5@1|root,32WND@2|Bacteria,1N9J7@1224|Proteobacteria,2W66E@28216|Betaproteobacteria,1KB1P@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3773625_5	1123253.AUBD01000011_gene2046	6.152e-116	393.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1X43V@135614|Xanthomonadales	135614|Xanthomonadales	CO	Thiol disulfide Interchange Protein	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
LZS1_k127_3773625_8	648757.Rvan_3031	3.053e-59	231.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,2U7PM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
LZS1_k127_3773625_17	1123242.JH636434_gene5030	1.014e-15	83.0	COG2204@1|root,COG2204@2|Bacteria,2IY95@203682|Planctomycetes	203682|Planctomycetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS1_k127_3773625_16	1283284.AZUK01000001_gene1679	1.487e-17	91.0	COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria,1T292@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16,TPR_19,TPR_8
LZS1_k127_3773625_14	1144319.PMI16_01473	1.799e-25	118.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,476PV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
LZS1_k127_3773625_0	382464.ABSI01000011_gene3052	4.133e-181	587.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia,2IU3F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	GcpE protein	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
LZS1_k127_3773625_11	396588.Tgr7_2795	6.127e-44	164.0	COG0346@1|root,COG0346@2|Bacteria,1RIR2@1224|Proteobacteria,1S7P4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS1_k127_3773625_15	1300345.LF41_3140	5.51e-18	89.0	COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria,1S5BT@1236|Gammaproteobacteria,1XAZ6@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	RDD
LZS1_k127_3773625_19	1278073.MYSTI_03189	1.515e-13	78.0	COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria	1224|Proteobacteria	S	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
LZS1_k127_3773625_1	378806.STAUR_6731	2.699e-174	560.0	COG1028@1|root,COG4221@1|root,COG1028@2|Bacteria,COG4221@2|Bacteria,1R4BM@1224|Proteobacteria,42PS2@68525|delta/epsilon subdivisions,2WJJK@28221|Deltaproteobacteria,2YU82@29|Myxococcales	28221|Deltaproteobacteria	IQ	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
LZS1_k127_3773625_12	886293.Sinac_1713	2.67e-39	148.0	COG1301@1|root,COG1301@2|Bacteria,2IYUE@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
LZS1_k127_378285_1	768671.ThimaDRAFT_0396	1.102e-18	93.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,1RQSM@1236|Gammaproteobacteria,1WZDX@135613|Chromatiales	135613|Chromatiales	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
LZS1_k127_378285_2	1121403.AUCV01000014_gene4606	1.82e-07	63.0	COG5338@1|root,COG5338@2|Bacteria,1QTI0@1224|Proteobacteria,42PG4@68525|delta/epsilon subdivisions,2WKB2@28221|Deltaproteobacteria,2MJF0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative beta-barrel porin 2	-	-	-	ko:K20920	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.66.3.1,1.B.66.3.2	-	-	BBP2_2
LZS1_k127_378285_0	1395587.P364_0129145	1.049e-46	175.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
LZS1_k127_3793175_0	663610.JQKO01000016_gene1583	3.229e-66	235.0	COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,2U4DJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS1_k127_3793175_1	330214.NIDE3702	1.261e-56	210.0	COG0306@1|root,COG0306@2|Bacteria,3J1D1@40117|Nitrospirae	40117|Nitrospirae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS1_k127_3793175_2	869210.Marky_2117	3.336e-46	175.0	COG2128@1|root,COG2128@2|Bacteria,1WMUS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS1_k127_3793175_6	1120956.JHZK01000005_gene2336	1.816e-06	53.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria,2UKC0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
LZS1_k127_3793175_5	1125863.JAFN01000001_gene2731	1.421e-28	121.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS1_k127_3793175_4	1173025.GEI7407_3459	2.28e-34	138.0	COG2032@1|root,COG2032@2|Bacteria,1G7HX@1117|Cyanobacteria,1HHGN@1150|Oscillatoriales	1117|Cyanobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
LZS1_k127_3793175_3	160799.PBOR_03075	3.503e-42	159.0	COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,26TH6@186822|Paenibacillaceae	91061|Bacilli	T	GAF domain-containing protein	ytsP	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
LZS1_k127_3794818_0	234267.Acid_3937	2.874e-122	396.0	COG0033@1|root,COG0033@2|Bacteria,3Y6EH@57723|Acidobacteria	57723|Acidobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS1_k127_3805858_1	338963.Pcar_2149	9.183e-62	223.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
LZS1_k127_3805858_0	1283300.ATXB01000001_gene1800	1.734e-170	546.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1XDMT@135618|Methylococcales	1236|Gammaproteobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS1_k127_3867701_1	1000569.HMPREF1040_1280	6.381e-87	293.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H1Z4@909932|Negativicutes	909932|Negativicutes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
LZS1_k127_3867701_2	1173028.ANKO01000148_gene1360	2.792e-56	209.0	COG1091@1|root,COG1091@2|Bacteria,1G3IE@1117|Cyanobacteria,1H8GQ@1150|Oscillatoriales	1117|Cyanobacteria	M	dTDP-4-dehydrorhamnose reductase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS1_k127_3867701_3	204773.HEAR0789	8.633e-15	85.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,478JS@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
LZS1_k127_3867701_0	292415.Tbd_1776	2.372e-180	569.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS1_k127_3867990_0	234267.Acid_3576	2.142e-72	263.0	COG1600@1|root,COG1600@2|Bacteria,3Y3TQ@57723|Acidobacteria	57723|Acidobacteria	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
LZS1_k127_3867990_1	944479.JQLX01000014_gene1511	4.954e-29	123.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2M6HK@213113|Desulfurellales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
LZS1_k127_3867990_2	290397.Adeh_2388	5.728e-21	97.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
LZS1_k127_3882029_2	357808.RoseRS_3170	3.76e-32	131.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi,375NG@32061|Chloroflexia	32061|Chloroflexia	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS1_k127_3882029_3	748449.Halha_2433	2.913e-13	84.0	COG1452@1|root,COG1452@2|Bacteria,1W2IS@1239|Firmicutes	1239|Firmicutes	M	Organic solvent tolerance protein OstA	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
LZS1_k127_3882029_1	1232410.KI421414_gene2855	4.607e-93	317.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria,43T7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS1_k127_3882029_0	351160.RCIX200	6.554e-107	371.0	COG1088@1|root,arCOG01371@2157|Archaea,2XUZX@28890|Euryarchaeota,2N94H@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS1_k127_3882029_4	518766.Rmar_2606	2.475e-11	65.0	COG1435@1|root,COG1435@2|Bacteria,4NE5R@976|Bacteroidetes,1FJ8E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
LZS1_k127_3897685_0	932678.THERU_00760	1.427e-20	109.0	COG0501@1|root,COG0501@2|Bacteria,2G3RN@200783|Aquificae	200783|Aquificae	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
LZS1_k127_3897821_2	109760.SPPG_06527T0	6.459e-26	116.0	COG0339@1|root,KOG2089@2759|Eukaryota,38SFI@33154|Opisthokonta,3NX1E@4751|Fungi	4751|Fungi	O	metallopeptidase MepB	PRD1	GO:0000322,GO:0000323,GO:0000324,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005773,GO:0005794,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0012505,GO:0016787,GO:0019538,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070011,GO:0070013,GO:0071704,GO:0140096,GO:1901564	3.4.24.37	ko:K01405,ko:K13726	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
LZS1_k127_3897821_0	1184267.A11Q_2038	4.627e-105	356.0	COG2866@1|root,COG2866@2|Bacteria,1MZYN@1224|Proteobacteria,42PTT@68525|delta/epsilon subdivisions,2MT5U@213481|Bdellovibrionales,2WS13@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Zn_pept	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14
LZS1_k127_3897821_1	1209989.TepiRe1_1565	3.788e-52	189.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,42GEH@68295|Thermoanaerobacterales	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS1_k127_3912012_1	1463856.JOHY01000059_gene1768	2.548e-42	175.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS1_k127_3912012_3	998088.B565_3379	2.125e-13	82.0	2DM20@1|root,31DN4@2|Bacteria,1R86I@1224|Proteobacteria,1S9Q6@1236|Gammaproteobacteria,1Y5Y7@135624|Aeromonadales	135624|Aeromonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3912012_4	456442.Mboo_1782	2.795e-10	68.0	arCOG11331@1|root,arCOG11331@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
LZS1_k127_3912012_0	1198114.AciX9_0264	2.722e-109	368.0	COG0493@1|root,COG0493@2|Bacteria,3Y3EA@57723|Acidobacteria,2JJCC@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	M00046	R00093,R00114,R00248,R00977,R01414,R10159,R11026	RC00006,RC00010,RC00072,RC00123,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
LZS1_k127_3912012_2	1227739.Hsw_1064	1.634e-27	113.0	COG0167@1|root,COG1149@1|root,COG0167@2|Bacteria,COG1149@2|Bacteria,4NGSB@976|Bacteroidetes,47U8D@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.1.1,1.3.98.1	ko:K00226,ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
LZS1_k127_3914676_2	518766.Rmar_0069	1.967e-32	146.0	COG0564@1|root,COG0564@2|Bacteria,4NHKH@976|Bacteroidetes	976|Bacteroidetes	J	Pseudouridine synthase	-	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
LZS1_k127_3914676_1	439235.Dalk_0047	2.175e-65	241.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2MI8B@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS1_k127_3914676_3	1236902.ANAS01000030_gene2951	3.56e-10	65.0	COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator MERR family	hspR	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
LZS1_k127_3914676_0	935548.KI912159_gene2921	2.081e-118	433.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,43J1Z@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS1_k127_3916875_0	502025.Hoch_6859	4.935e-44	181.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2YV8N@29|Myxococcales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
LZS1_k127_3991496_5	1121380.JNIW01000122_gene310	8.751e-26	115.0	29FE7@1|root,302BX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_3991496_3	316274.Haur_1661	8.968e-74	258.0	COG2962@1|root,COG2962@2|Bacteria,2G6C2@200795|Chloroflexi,375DH@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM RarD protein, DMT superfamily transporter	-	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
LZS1_k127_3991496_2	477974.Daud_1972	1.478e-94	332.0	COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,24ASU@186801|Clostridia,263XJ@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp
LZS1_k127_3991496_4	55601.VANGNB10_cI0062c	2.212e-52	206.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1XUDA@135623|Vibrionales	135623|Vibrionales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0003674,GO:0003824,GO:0004638,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
LZS1_k127_3991496_0	262724.TT_C0460	4.107e-112	383.0	COG0151@1|root,COG0151@2|Bacteria,1WIXZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
LZS1_k127_3991496_1	401526.TcarDRAFT_1563	1.549e-101	347.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4H2AT@909932|Negativicutes	909932|Negativicutes	NU	Type II IV secretion system protein	epsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
LZS1_k127_4001481_0	1232410.KI421424_gene1682	5.604e-89	310.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,43SBC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TRAM domain	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
LZS1_k127_4001481_1	644282.Deba_0825	1.03e-65	235.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
LZS1_k127_4002064_2	118168.MC7420_7883	0.0002546	52.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H6WA@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_4002064_1	639030.JHVA01000001_gene3220	0.000251	53.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HC@57723|Acidobacteria,2JKE0@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,TPR_16
LZS1_k127_4002064_0	1185876.BN8_00865	3.825e-05	55.0	28N78@1|root,2ZBBY@2|Bacteria,4NGF9@976|Bacteroidetes,47X4G@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
LZS1_k127_4014838_0	760117.JN27_13320	5.915e-63	234.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS1_k127_4019704_4	290397.Adeh_2759	1.195e-14	87.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42V9P@68525|delta/epsilon subdivisions,2X5QW@28221|Deltaproteobacteria,2Z1ZE@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
LZS1_k127_4019704_1	262724.TT_C0824	2.154e-24	116.0	COG1502@1|root,COG1502@2|Bacteria,1WJ7I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
LZS1_k127_4019704_2	1209989.TepiRe1_2355	2.628e-18	90.0	COG2119@1|root,COG2119@2|Bacteria,1UR7U@1239|Firmicutes,24QEI@186801|Clostridia,42GXZ@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
LZS1_k127_4019704_3	1122951.ATUE01000005_gene2018	1.058e-16	91.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
LZS1_k127_4019704_0	237368.SCABRO_03142	3.128e-50	194.0	COG1355@1|root,COG1355@2|Bacteria,2IZEZ@203682|Planctomycetes	203682|Planctomycetes	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
LZS1_k127_4027697_0	484019.THA_203	2.268e-68	248.0	COG1351@1|root,COG1351@2|Bacteria,2GC26@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
LZS1_k127_4027697_3	247490.KSU1_D0917	4.156e-14	86.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
LZS1_k127_4027697_1	1077972.ARGLB_083_01950	2.434e-28	118.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,1W7R4@1268|Micrococcaceae	201174|Actinobacteria	T	response regulator	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_4027697_2	717231.Flexsi_0230	2.584e-15	89.0	COG5616@1|root,COG5616@2|Bacteria,2GEM2@200930|Deferribacteres	200930|Deferribacteres	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4038892_0	1121423.JONT01000001_gene1927	3.682e-71	259.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,260FS@186807|Peptococcaceae	186801|Clostridia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
LZS1_k127_4085018_0	204669.Acid345_1739	3.014e-101	337.0	COG0761@1|root,COG0761@2|Bacteria,3Y40M@57723|Acidobacteria,2JIXC@204432|Acidobacteriia	204432|Acidobacteriia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
LZS1_k127_4085018_1	1056820.KB900639_gene374	2.536e-71	246.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,2PNDZ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	L	EXOIII	orn	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
LZS1_k127_4085018_3	330214.NIDE1646	1.654e-36	146.0	2EUFJ@1|root,33MXU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
LZS1_k127_4085018_2	391615.ABSJ01000054_gene1467	1.666e-61	218.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria,1JAIZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
LZS1_k127_4085018_4	925409.KI911562_gene778	1.498e-28	130.0	COG3014@1|root,COG3014@2|Bacteria,4NIIU@976|Bacteroidetes,1IR21@117747|Sphingobacteriia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	TPR_2
LZS1_k127_4108420_0	930171.Asphe3_37340	0.0001496	55.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,1W8RN@1268|Micrococcaceae	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS1_k127_411711_1	32057.KB217478_gene3544	5.686e-06	53.0	COG1413@1|root,COG1413@2|Bacteria,1GHRB@1117|Cyanobacteria,1HSJZ@1161|Nostocales	1117|Cyanobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
LZS1_k127_411711_0	404589.Anae109_1681	1.425e-119	389.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria	1224|Proteobacteria	C	Aldo keto reductase	yghZ	GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	iSBO_1134.SBO_2995	Aldo_ket_red
LZS1_k127_4130615_1	1487953.JMKF01000080_gene4212	3.324e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,1G420@1117|Cyanobacteria,1H9RD@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
LZS1_k127_4130615_0	1121015.N789_01080	3.529e-18	100.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X30C@135614|Xanthomonadales	1224|Proteobacteria	M	NAD dependent epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS1_k127_4131336_1	1499967.BAYZ01000060_gene5985	7.512e-73	277.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,2NR14@2323|unclassified Bacteria	2|Bacteria	U	Patatin-like phospholipase	CP_0464	-	-	ko:K01999,ko:K07001	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Patatin,cNMP_binding
LZS1_k127_4131336_2	264732.Moth_1504	1.21e-46	177.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
LZS1_k127_4131336_0	720554.Clocl_2233	1.637e-88	305.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS1_k127_4140597_0	1184267.A11Q_936	5.369e-33	139.0	COG0697@1|root,COG0697@2|Bacteria,1PIF3@1224|Proteobacteria,42SMV@68525|delta/epsilon subdivisions,2MUGZ@213481|Bdellovibrionales,2WPAJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_4146105_2	1254432.SCE1572_12645	5.887e-34	144.0	COG0644@1|root,COG0644@2|Bacteria,1N3JT@1224|Proteobacteria,42S0W@68525|delta/epsilon subdivisions,2WVDD@28221|Deltaproteobacteria,2YU0R@29|Myxococcales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS1_k127_4146105_6	1095767.CAHD01000188_gene237	1.411e-15	82.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4F0P8@85016|Cellulomonadaceae	201174|Actinobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS1_k127_4146105_5	118166.JH976537_gene2717	1.667e-17	87.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G09B@1117|Cyanobacteria,1H71H@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
LZS1_k127_4146105_4	690850.Desaf_1512	5.056e-18	85.0	COG1942@1|root,COG1942@2|Bacteria,1N6WW@1224|Proteobacteria,42V9V@68525|delta/epsilon subdivisions,2WRUI@28221|Deltaproteobacteria,2MD44@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM 4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
LZS1_k127_4146105_0	861299.J421_6133	7.227e-79	273.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	dcsG	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,RimK
LZS1_k127_4146105_1	1121946.AUAX01000005_gene5485	5.153e-51	203.0	COG0612@1|root,COG0612@2|Bacteria,2GKAT@201174|Actinobacteria,4DBWR@85008|Micromonosporales	201174|Actinobacteria	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS1_k127_4146105_3	1961.JOAK01000010_gene6670	2.555e-18	100.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS1_k127_4159185_4	1121918.ARWE01000001_gene1939	4.406e-55	206.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,43S6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
LZS1_k127_4159185_1	289376.THEYE_A1543	4.148e-89	300.0	COG0528@1|root,COG0528@2|Bacteria,3J0BE@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS1_k127_4159185_5	1160721.RBI_II00035	1.2e-47	177.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3WIRX@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
LZS1_k127_4159185_2	1340493.JNIF01000003_gene4513	2.05e-83	282.0	COG0020@1|root,COG0020@2|Bacteria,3Y485@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
LZS1_k127_4159185_6	515635.Dtur_1198	3.705e-35	144.0	COG4589@1|root,COG4589@2|Bacteria	2|Bacteria	S	phosphatidate cytidylyltransferase activity	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
LZS1_k127_4159185_0	321327.CYA_0193	1.164e-104	353.0	COG0743@1|root,COG0743@2|Bacteria,1G2CU@1117|Cyanobacteria,1GYKR@1129|Synechococcus	1117|Cyanobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
LZS1_k127_4159185_3	1125863.JAFN01000001_gene963	1.196e-55	220.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
LZS1_k127_4159185_7	1141662.OOA_14112	1.094e-31	125.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,3Z8QG@586|Providencia	1236|Gammaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
LZS1_k127_4165286_0	641491.DND132_1381	2.186e-54	218.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MANW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM,TPR_1,TPR_14,TPR_16
LZS1_k127_4165286_1	370438.PTH_2370	1.001e-24	119.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,24EST@186801|Clostridia,2607Q@186807|Peptococcaceae	186801|Clostridia	C	Nif11-class bacteriocin maturation radical SAM enzyme	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_4165286_2	1160137.KB907307_gene1149	1.952e-19	100.0	COG0641@1|root,COG0641@2|Bacteria,2GMTV@201174|Actinobacteria,4FY6K@85025|Nocardiaceae	201174|Actinobacteria	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_14,Radical_SAM,SEC-C,SPASM
LZS1_k127_4171539_5	330214.NIDE3611	1.929e-08	56.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
LZS1_k127_4171539_2	395964.KE386496_gene1800	4.071e-27	120.0	COG1011@1|root,COG1011@2|Bacteria,1Q6A0@1224|Proteobacteria,2V96W@28211|Alphaproteobacteria,3NBWJ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS1_k127_4171539_3	380358.XALC_2740	5.58e-24	114.0	COG1331@1|root,COG1331@2|Bacteria,1QWIF@1224|Proteobacteria,1T2VZ@1236|Gammaproteobacteria,1XD6X@135614|Xanthomonadales	135614|Xanthomonadales	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
LZS1_k127_4171539_1	635013.TherJR_1190	1.295e-43	170.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,261JW@186807|Peptococcaceae	186801|Clostridia	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_4171539_0	1121920.AUAU01000008_gene1683	1.136e-49	201.0	COG0190@1|root,COG0190@2|Bacteria	2|Bacteria	F	methenyltetrahydrofolate cyclohydrolase activity	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
LZS1_k127_4171539_4	1254432.SCE1572_46460	5.034e-09	68.0	COG3540@1|root,COG3540@2|Bacteria,1NE6K@1224|Proteobacteria,43562@68525|delta/epsilon subdivisions,2WZH2@28221|Deltaproteobacteria,2Z24U@29|Myxococcales	28221|Deltaproteobacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
LZS1_k127_4171539_6	626939.HMPREF9443_00632	3.926e-05	48.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4H37C@909932|Negativicutes	909932|Negativicutes	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
LZS1_k127_4181901_3	521011.Mpal_1730	0.0002602	51.0	COG3620@1|root,arCOG00608@2157|Archaea,2XTDG@28890|Euryarchaeota,2N9J9@224756|Methanomicrobia	224756|Methanomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A2079	CBS,HTH_3
LZS1_k127_4181901_1	1192034.CAP_6275	1.554e-88	297.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2YX8R@29|Myxococcales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS1_k127_4181901_2	1444712.BN1013_00282	3.189e-28	129.0	COG0546@1|root,COG0546@2|Bacteria,2JG2T@204428|Chlamydiae	204428|Chlamydiae	S	Protein of unknown function (DUF2608)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2608
LZS1_k127_4181901_0	1189612.A33Q_0099	2.851e-228	726.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,47M5V@768503|Cytophagia	976|Bacteroidetes	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
LZS1_k127_4201384_1	309799.DICTH_1037	1.075e-60	213.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS1_k127_4201384_0	886293.Sinac_1500	9.478e-246	783.0	COG1297@1|root,COG1297@2|Bacteria,2IYGI@203682|Planctomycetes	203682|Planctomycetes	S	PFAM OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
LZS1_k127_4224546_5	1144275.COCOR_07305	2.988e-27	121.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2YUQ9@29|Myxococcales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
LZS1_k127_4224546_6	693746.OBV_00700	1.397e-22	111.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,2N6B1@216572|Oscillospiraceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS1_k127_4224546_0	877455.Metbo_0229	1.282e-233	741.0	COG0443@1|root,arCOG03060@2157|Archaea,2XT86@28890|Euryarchaeota,23NSE@183925|Methanobacteria	183925|Methanobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS1_k127_4224546_1	383381.EH30_06005	1.106e-104	351.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,2K1EY@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS1_k127_4224546_3	720554.Clocl_2765	2.927e-39	156.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
LZS1_k127_4224546_4	1121430.JMLG01000001_gene2275	1.907e-37	146.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,262CU@186807|Peptococcaceae	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
LZS1_k127_4224546_7	1408422.JHYF01000002_gene2433	1.287e-07	57.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,36MKD@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
LZS1_k127_4224546_2	767817.Desgi_1377	1.55e-95	335.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,2600X@186807|Peptococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
LZS1_k127_4231578_4	1205910.B005_3761	1.52e-09	60.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,4EHF4@85012|Streptosporangiales	201174|Actinobacteria	G	Ribulose-phosphate 3 epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
LZS1_k127_4231578_2	926566.Terro_2449	4.28e-16	80.0	COG0228@1|root,COG0228@2|Bacteria,3Y56G@57723|Acidobacteria,2JJQF@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
LZS1_k127_4231578_3	522772.Dacet_2280	5.973e-11	70.0	COG1837@1|root,COG1837@2|Bacteria,2GFZI@200930|Deferribacteres	200930|Deferribacteres	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
LZS1_k127_4231578_0	515635.Dtur_1534	1.236e-76	266.0	COG0336@1|root,COG0336@2|Bacteria	2|Bacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228,4.6.1.12	ko:K00554,ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R00597,R05637	RC00002,RC00003,RC00334,RC01440	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA_m1G_MT
LZS1_k127_4231578_1	1120973.AQXL01000083_gene2904	3.093e-36	146.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
LZS1_k127_4231578_5	1473546.CH76_00470	3.189e-08	58.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,3IXGH@400634|Lysinibacillus	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS1_k127_4297391_13	1125863.JAFN01000001_gene2231	1.845e-25	111.0	COG4659@1|root,COG4659@2|Bacteria,1N2GK@1224|Proteobacteria,42UH0@68525|delta/epsilon subdivisions,2WRRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4297391_12	671143.DAMO_2902	2.785e-31	129.0	2CKY4@1|root,328RE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4297391_7	697282.Mettu_3942	4.744e-78	264.0	COG2193@1|root,COG2193@2|Bacteria,1RF3C@1224|Proteobacteria,1S72I@1236|Gammaproteobacteria,1XF6G@135618|Methylococcales	135618|Methylococcales	P	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
LZS1_k127_4297391_11	1123508.JH636448_gene7577	2.71e-36	144.0	COG1999@1|root,COG1999@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
LZS1_k127_4297391_0	1297742.A176_02045	0.0	1150.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUIQ@29|Myxococcales	28221|Deltaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
LZS1_k127_4297391_3	1242864.D187_000078	1.44e-164	523.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,42ME8@68525|delta/epsilon subdivisions,2WP73@28221|Deltaproteobacteria,2YUD6@29|Myxococcales	28221|Deltaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
LZS1_k127_4297391_1	1034943.BN1094_01740	6.335e-287	896.0	COG0330@1|root,COG0330@2|Bacteria,1MW1D@1224|Proteobacteria,1SN0S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS1_k127_4297391_5	251221.35211327	8.864e-100	334.0	COG0031@1|root,COG0031@2|Bacteria,1GBK3@1117|Cyanobacteria	1117|Cyanobacteria	E	Cysteine synthase B	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS1_k127_4297391_16	545695.TREAZ_1613	5.398e-20	104.0	COG1310@1|root,COG1310@2|Bacteria,2JAFD@203691|Spirochaetes	203691|Spirochaetes	S	JAB/MPN domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
LZS1_k127_4297391_2	1267535.KB906767_gene1049	1.605e-166	548.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
LZS1_k127_4297391_14	1046724.KB889900_gene3205	2.916e-25	112.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,46AKM@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	ThiF family	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,Rhodanese,ThiF,ThiS
LZS1_k127_4297391_10	237368.SCABRO_01183	6.128e-44	166.0	COG0607@1|root,COG0607@2|Bacteria,2IZ80@203682|Planctomycetes	203682|Planctomycetes	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
LZS1_k127_4297391_9	1158165.KB898875_gene215	1.395e-51	192.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1WX0V@135613|Chromatiales	135613|Chromatiales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
LZS1_k127_4297391_15	644282.Deba_0905	1.52e-21	107.0	COG1503@1|root,COG1503@2|Bacteria,1NHEV@1224|Proteobacteria,42XGN@68525|delta/epsilon subdivisions,2WTEW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
LZS1_k127_4297391_17	1304885.AUEY01000005_gene888	7.375e-10	65.0	2E1HF@1|root,32WVJ@2|Bacteria,1NHTX@1224|Proteobacteria,42X6V@68525|delta/epsilon subdivisions,2WSSD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4297391_6	56780.SYN_02199	1.985e-79	281.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,43BJA@68525|delta/epsilon subdivisions,2WME6@28221|Deltaproteobacteria,2MS70@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS1_k127_4297391_4	84531.JMTZ01000070_gene1816	4.748e-111	368.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS1_k127_4297391_8	1380387.JADM01000002_gene1990	7.461e-64	232.0	COG3738@1|root,COG3738@2|Bacteria,1RE1M@1224|Proteobacteria,1S44B@1236|Gammaproteobacteria,1XP2W@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
LZS1_k127_4331189_8	479432.Sros_4287	0.0004635	51.0	COG1132@1|root,COG1413@1|root,COG1132@2|Bacteria,COG1413@2|Bacteria,2I6NK@201174|Actinobacteria	201174|Actinobacteria	V	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4331189_5	402881.Plav_0855	2.772e-44	171.0	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,2UBX1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
LZS1_k127_4331189_2	1278078.G419_11792	1.284e-72	261.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,4FTX7@85025|Nocardiaceae	201174|Actinobacteria	E	Homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
LZS1_k127_4331189_0	671143.DAMO_0588	4.309e-121	398.0	COG0498@1|root,COG0498@2|Bacteria,2NP4T@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0546,iSB619.SA_RS06615,iYO844.BSU32250	PALP
LZS1_k127_4331189_3	1120985.AUMI01000015_gene1652	1.135e-68	244.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4H272@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS1_k127_4331189_1	246194.CHY_1909	1.258e-102	360.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,42FQX@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
LZS1_k127_4331189_4	118166.JH976537_gene2018	2.189e-56	209.0	COG0847@1|root,COG0847@2|Bacteria,1G66K@1117|Cyanobacteria,1HEXZ@1150|Oscillatoriales	1117|Cyanobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
LZS1_k127_4331189_6	204669.Acid345_3975	1.249e-14	87.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
LZS1_k127_4331189_7	502025.Hoch_1914	1.869e-12	69.0	297WK@1|root,2ZV33@2|Bacteria,1P83J@1224|Proteobacteria,432YB@68525|delta/epsilon subdivisions,2WYBG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4355227_3	670487.Ocepr_1873	1.56e-27	118.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
LZS1_k127_4355227_0	580327.Tthe_2222	1.016e-99	332.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,42FEE@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
LZS1_k127_4355227_2	1033743.CAES01000050_gene602	1.436e-39	166.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,4HC4H@91061|Bacilli,26T37@186822|Paenibacillaceae	91061|Bacilli	S	Alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
LZS1_k127_4355227_1	693986.MOC_4789	2.588e-72	266.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,1JR45@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
LZS1_k127_4384093_1	1120999.JONM01000026_gene1527	2.696e-118	394.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,2KPRT@206351|Neisseriales	206351|Neisseriales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
LZS1_k127_4384093_0	338963.Pcar_1613	5.106e-133	433.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
LZS1_k127_4384093_2	1379281.AVAG01000033_gene464	2.97e-43	163.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2M8J7@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
LZS1_k127_4385342_3	518766.Rmar_2816	3.627e-24	114.0	COG5632@1|root,COG5632@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447,ko:K17733	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01002,ko01011	-	-	-	Amidase_2,Big_2
LZS1_k127_4385342_4	330214.NIDE3871	2.036e-08	63.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
LZS1_k127_4385342_2	1288494.EBAPG3_10110	3.651e-26	115.0	2BW7N@1|root,32Z97@2|Bacteria,1P2ZF@1224|Proteobacteria,2W4Y3@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4385342_1	1121861.KB899934_gene519	3.888e-27	127.0	COG4191@1|root,COG4191@2|Bacteria,1MVK7@1224|Proteobacteria,2TR44@28211|Alphaproteobacteria,2JQ26@204441|Rhodospirillales	204441|Rhodospirillales	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
LZS1_k127_4385342_0	696281.Desru_3313	1.439e-40	158.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_4395333_0	945713.IALB_1259	3.7e-06	59.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4402863_1	1123242.JH636434_gene4770	1.611e-84	288.0	COG0205@1|root,COG0205@2|Bacteria,2IYJ6@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS1_k127_4402863_3	880073.Calab_2091	2.558e-11	75.0	2CBA8@1|root,30BZT@2|Bacteria,2NR2H@2323|unclassified Bacteria	2|Bacteria	S	Exopolysaccharide biosynthesis protein YbjH	-	-	-	-	-	-	-	-	-	-	-	-	YjbH
LZS1_k127_4402863_2	981369.JQMJ01000004_gene6487	8.859e-22	99.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,2NG98@228398|Streptacidiphilus	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	mprA	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_4402863_0	1089553.Tph_c09340	1.048e-209	681.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS1_k127_4422954_2	886379.AEWI01000012_gene1155	2.508e-22	97.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia,3XK5J@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S9/S16	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS1_k127_4422954_1	693661.Arcve_1500	7.85e-28	121.0	COG1801@1|root,arCOG04291@2157|Archaea,2XWUT@28890|Euryarchaeota,246KF@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS1_k127_4422954_3	1040987.AZUY01000042_gene88	4.642e-18	96.0	COG0463@1|root,COG0500@1|root,COG0726@1|root,COG0463@2|Bacteria,COG0500@2|Bacteria,COG0726@2|Bacteria,1R7PS@1224|Proteobacteria,2TU1B@28211|Alphaproteobacteria,43PBY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	GMQ	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,NodS,Polysacc_deac_1
LZS1_k127_4422954_0	335543.Sfum_0741	1.355e-88	310.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2MQ91@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
LZS1_k127_4495415_2	1068980.ARVW01000001_gene4002	1.689e-27	115.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4DXU7@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS1_k127_4495415_3	234267.Acid_1010	7.295e-09	58.0	COG1826@1|root,COG1826@2|Bacteria,3Y5V7@57723|Acidobacteria	57723|Acidobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
LZS1_k127_4495415_1	316067.Geob_0485	2.601e-35	150.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WM5B@28221|Deltaproteobacteria,43U8X@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
LZS1_k127_4495415_0	338963.Pcar_1369	1.155e-42	167.0	COG2108@1|root,COG2108@2|Bacteria,1MY1Y@1224|Proteobacteria,42MIQ@68525|delta/epsilon subdivisions,2WJD2@28221|Deltaproteobacteria,43TNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS1_k127_4512231_5	264462.Bd1557	7.574e-85	301.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,Peptidase_S74
LZS1_k127_4512231_2	1249997.JHZW01000002_gene190	1.237e-99	333.0	COG2159@1|root,COG2159@2|Bacteria,4NJP9@976|Bacteroidetes,1HXKV@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS1_k127_4512231_11	292415.Tbd_1259	4.201e-31	130.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,2VUZW@28216|Betaproteobacteria,1KSDS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
LZS1_k127_4512231_3	1121920.AUAU01000011_gene149	7.863e-96	328.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08162,ko:K08226,ko:K16211	-	-	-	-	ko00000,ko02000	2.A.1.2.21,2.A.1.41,2.A.2.6	-	-	MFS_1,PUCC
LZS1_k127_4512231_0	344747.PM8797T_03660	3.264e-226	713.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
LZS1_k127_4512231_6	589865.DaAHT2_0013	1.328e-83	294.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria,2MJZP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
LZS1_k127_4512231_8	667014.Thein_1852	3.042e-74	261.0	COG4956@1|root,COG4956@2|Bacteria,2GGWP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
LZS1_k127_4512231_1	1033734.CAET01000080_gene3305	1.681e-124	414.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1ZB8H@1386|Bacillus	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
LZS1_k127_4512231_12	1379858.N508_01447	1.593e-14	86.0	COG1463@1|root,COG1463@2|Bacteria,2GEQX@200930|Deferribacteres	200930|Deferribacteres	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
LZS1_k127_4512231_7	1379698.RBG1_1C00001G0979	1.941e-75	273.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
LZS1_k127_4512231_9	1125863.JAFN01000001_gene564	7.067e-57	208.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
LZS1_k127_4512231_4	867903.ThesuDRAFT_02308	1.835e-92	322.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WCG8@538999|Clostridiales incertae sedis	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
LZS1_k127_4512231_10	401053.AciPR4_4080	5.524e-36	140.0	COG0305@1|root,COG0305@2|Bacteria,3Y335@57723|Acidobacteria,2JI73@204432|Acidobacteriia	204432|Acidobacteriia	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
LZS1_k127_4518107_1	264462.Bd3206	2.215e-42	168.0	COG0400@1|root,COG0400@2|Bacteria,1N0UF@1224|Proteobacteria,42TUA@68525|delta/epsilon subdivisions,2MT5K@213481|Bdellovibrionales,2WQDY@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Serine hydrolase (FSH1)	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
LZS1_k127_4518107_0	886293.Sinac_2294	4.309e-299	933.0	COG1032@1|root,COG1032@2|Bacteria,2IY6B@203682|Planctomycetes	203682|Planctomycetes	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
LZS1_k127_4518107_2	203124.Tery_1656	3.647e-09	70.0	COG3271@1|root,COG3271@2|Bacteria,1G7KY@1117|Cyanobacteria,1HD6K@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4520167_8	330214.NIDE3419	9.936e-21	96.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,Glyco_trans_1_4,NAD_binding_8
LZS1_k127_4520167_6	552811.Dehly_0536	4.052e-63	232.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
LZS1_k127_4520167_5	720554.Clocl_3273	1.154e-63	226.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,3WHU8@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
LZS1_k127_4520167_7	1303518.CCALI_02064	7.516e-42	163.0	COG0602@1|root,COG0602@2|Bacteria	2|Bacteria	H	queuosine metabolic process	queE	-	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100	-	R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
LZS1_k127_4520167_12	868595.Desca_0986	5.549e-07	61.0	28NT3@1|root,2ZBRV@2|Bacteria,1V1C2@1239|Firmicutes,257E3@186801|Clostridia	186801|Clostridia	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
LZS1_k127_4520167_0	204669.Acid345_0668	5.206e-137	448.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
LZS1_k127_4520167_2	1210884.HG799462_gene8369	4.032e-78	268.0	COG2057@1|root,COG2057@2|Bacteria	2|Bacteria	I	CoA-transferase activity	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS1_k127_4520167_1	224325.AF_1199	2.757e-81	288.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS1_k127_4520167_9	118166.JH976537_gene204	1.012e-19	93.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
LZS1_k127_4520167_11	1288826.MSNKSG1_16121	2.471e-16	92.0	COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,1RQZW@1236|Gammaproteobacteria,464FX@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS1_k127_4520167_10	1550073.JROH01000010_gene1182	8.741e-18	94.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2TTDJ@28211|Alphaproteobacteria,2K1MT@204457|Sphingomonadales	204457|Sphingomonadales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS1_k127_4520167_3	176299.Atu0832	1.166e-71	258.0	COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2TT6V@28211|Alphaproteobacteria,4BA39@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Chloride channel protein	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
LZS1_k127_4520167_4	485915.Dret_1750	2.053e-65	231.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
LZS1_k127_4534827_2	1177928.TH2_13464	4.385e-19	89.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,2JT97@204441|Rhodospirillales	204441|Rhodospirillales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
LZS1_k127_4534827_0	118005.AWNK01000010_gene361	8.623e-106	362.0	COG0342@1|root,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS1_k127_4534827_1	713586.KB900536_gene428	2.624e-66	238.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1WX0P@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS1_k127_4534827_3	637390.AFOH01000012_gene688	1.363e-05	56.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SACF@1236|Gammaproteobacteria,2NBVJ@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
LZS1_k127_4568772_13	338963.Pcar_2042	1.366e-12	71.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,43S23@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
LZS1_k127_4568772_6	1173029.JH980292_gene1147	1.485e-34	144.0	COG0739@1|root,COG0739@2|Bacteria,1G1GS@1117|Cyanobacteria,1H8FP@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Peptidase family M23	nlpD	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
LZS1_k127_4568772_1	1121373.KB903663_gene1070	1.825e-67	233.0	COG0221@1|root,COG0221@2|Bacteria,4NGBU@976|Bacteroidetes,47M21@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
LZS1_k127_4568772_0	1131269.AQVV01000002_gene1205	6.603e-90	318.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
LZS1_k127_4568772_9	1205680.CAKO01000002_gene2119	9.826e-24	115.0	COG5285@1|root,COG5285@2|Bacteria,1R6HP@1224|Proteobacteria,2UHSD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS1_k127_4568772_10	1121360.AUAQ01000017_gene2482	3.663e-21	103.0	COG2120@1|root,COG2120@2|Bacteria,2GMXC@201174|Actinobacteria,22NCW@1653|Corynebacteriaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS1_k127_4568772_12	1121439.dsat_0482	9.548e-15	79.0	COG1734@1|root,COG1734@2|Bacteria,1N7D8@1224|Proteobacteria,42VPI@68525|delta/epsilon subdivisions,2WRHT@28221|Deltaproteobacteria,2MDC0@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS1_k127_4568772_8	99598.Cal7507_2060	9.364e-24	113.0	COG2227@1|root,COG2227@2|Bacteria,1GQK6@1117|Cyanobacteria,1HMYV@1161|Nostocales	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
LZS1_k127_4568772_4	1125863.JAFN01000001_gene1946	1.129e-49	190.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42PVD@68525|delta/epsilon subdivisions,2WN8S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS1_k127_4568772_14	290397.Adeh_3982	1.029e-11	73.0	2D6MI@1|root,30AQT@2|Bacteria,1P8HC@1224|Proteobacteria	1224|Proteobacteria	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
LZS1_k127_4568772_3	1121920.AUAU01000004_gene870	2.276e-58	215.0	COG0053@1|root,COG0053@2|Bacteria,3Y5VF@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
LZS1_k127_4568772_5	330214.NIDE3490	3.208e-38	148.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
LZS1_k127_4568772_7	1035197.HMPREF9999_00956	1.424e-30	131.0	COG1917@1|root,COG1917@2|Bacteria,4NSB6@976|Bacteroidetes,2FT3R@200643|Bacteroidia,1WDZ6@1283313|Alloprevotella	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS1_k127_4568772_15	456442.Mboo_0629	1.468e-06	55.0	arCOG09584@1|root,arCOG09584@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4568772_11	47763.JNZA01000036_gene2459	1.274e-15	91.0	COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria	201174|Actinobacteria	L	Alpha beta hydrolase	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
LZS1_k127_4568772_2	1403819.BATR01000009_gene305	9.648e-67	245.0	COG0275@1|root,COG0275@2|Bacteria,46UK9@74201|Verrucomicrobia,2IVBZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	MraW methylase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_5
LZS1_k127_4568772_16	323259.Mhun_0617	0.0007219	50.0	COG5635@1|root,arCOG02967@2157|Archaea	2157|Archaea	T	PBS lyase HEAT-like repeat	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS,Thioredoxin_3
LZS1_k127_4569266_12	765913.ThidrDRAFT_0323	3.031e-08	56.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1WWF8@135613|Chromatiales	135613|Chromatiales	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
LZS1_k127_4569266_13	558884.JRGM01000009_gene3306	2.847e-06	57.0	COG3700@1|root,COG3700@2|Bacteria,1PRRA@1224|Proteobacteria,1RP0N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the class B bacterial acid phosphatase family	aphA	GO:0003674,GO:0003824,GO:0003993,GO:0004647,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030288,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0044237,GO:0044464,GO:0048037	3.1.3.2	ko:K03788	ko00740,ko01100,map00740,map01100	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_4476,iYL1228.KPN_04442	Acid_phosphat_B
LZS1_k127_4569266_3	1242864.D187_005683	8.597e-77	265.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,2YU88@29|Myxococcales	28221|Deltaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
LZS1_k127_4569266_5	717605.Theco_2018	1.5e-56	213.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,4HAG3@91061|Bacilli,26T3U@186822|Paenibacillaceae	91061|Bacilli	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	2242	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
LZS1_k127_4569266_8	913865.DOT_6144	3.885e-29	119.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,265RN@186807|Peptococcaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
LZS1_k127_4569266_9	1184609.KILIM_086_00040	3.417e-25	107.0	COG4576@1|root,COG4576@2|Bacteria,2GT97@201174|Actinobacteria	201174|Actinobacteria	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
LZS1_k127_4569266_0	406124.ACPC01000022_gene4197	1.568e-127	424.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,4IS6J@91061|Bacilli,1ZSC0@1386|Bacillus	91061|Bacilli	C	Aldehyde dehydrogenase family	acdH	-	1.1.1.1,1.2.1.10,1.2.1.87	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927,R09097	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
LZS1_k127_4569266_7	411467.BACCAP_01552	6.507e-30	128.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,267XA@186813|unclassified Clostridiales	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
LZS1_k127_4569266_6	479436.Vpar_1094	2.232e-36	143.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4H4IP@909932|Negativicutes	909932|Negativicutes	G	isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
LZS1_k127_4569266_4	1242864.D187_003088	2.623e-60	231.0	COG2931@1|root,COG3055@1|root,COG2931@2|Bacteria,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
LZS1_k127_4569266_1	96561.Dole_2898	1.641e-81	295.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
LZS1_k127_4569266_11	1123075.AUDP01000004_gene820	1.693e-13	80.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,3WMQW@541000|Ruminococcaceae	186801|Clostridia	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
LZS1_k127_4569266_10	215803.DB30_2248	2.951e-15	79.0	COG4576@1|root,COG4576@2|Bacteria,1Q8QH@1224|Proteobacteria,4354D@68525|delta/epsilon subdivisions,2WZFG@28221|Deltaproteobacteria,2Z20V@29|Myxococcales	28221|Deltaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
LZS1_k127_4569266_2	1214166.ALLG01000021_gene36	1.525e-79	277.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1WT0K@1307|Streptococcus suis	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835	DeoC
LZS1_k127_4618731_0	497964.CfE428DRAFT_4597	1.25e-208	662.0	COG4108@1|root,COG4108@2|Bacteria,46SF9@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
LZS1_k127_4618731_2	743720.Psefu_0275	6.137e-46	176.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1YVTG@136845|Pseudomonas putida group	1236|Gammaproteobacteria	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_4618731_1	485913.Krac_12092	6.59e-184	600.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS1_k127_4618731_3	649831.L083_7555	5.019e-08	63.0	COG2091@1|root,COG3321@1|root,COG2091@2|Bacteria,COG3321@2|Bacteria,2HEYM@201174|Actinobacteria,4DHEV@85008|Micromonosporales	201174|Actinobacteria	Q	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS,Acyl_transf_1,KAsynt_C_assoc,Ketoacyl-synt_C,PS-DH,ketoacyl-synt
LZS1_k127_4621905_7	795797.C497_17692	1.302e-06	55.0	COG0642@1|root,COG0784@1|root,arCOG02386@2157|Archaea,arCOG06219@2157|Archaea,2XVHV@28890|Euryarchaeota,23UV0@183963|Halobacteria	183963|Halobacteria	T	COG0784 FOG CheY-like receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
LZS1_k127_4621905_9	469383.Cwoe_5361	0.0001502	50.0	COG0784@1|root,COG2208@1|root,COG0784@2|Bacteria,COG2208@2|Bacteria,2GNAF@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
LZS1_k127_4621905_0	1295642.H839_13824	2.65e-147	501.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4HAZK@91061|Bacilli,1WEEV@129337|Geobacillus	91061|Bacilli	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS1_k127_4621905_1	1125863.JAFN01000001_gene527	9.252e-31	134.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
LZS1_k127_4621905_5	857087.Metme_3465	2.089e-14	76.0	COG2026@1|root,COG2026@2|Bacteria,1N76D@1224|Proteobacteria,1SCNM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DJ	TIGRFAM Addiction module toxin, RelE StbE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
LZS1_k127_4621905_8	1304865.JAGF01000001_gene2	4.144e-05	52.0	COG2161@1|root,COG2161@2|Bacteria,2GZ91@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
LZS1_k127_4621905_2	1003195.SCAT_4987	7.355e-29	123.0	2B894@1|root,321HR@2|Bacteria,2H5JU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4621905_3	1173028.ANKO01000247_gene3954	3.087e-28	116.0	2E46S@1|root,32Z2Q@2|Bacteria,1GA29@1117|Cyanobacteria,1HHD8@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4621905_6	330214.NIDE1072	8.88e-13	70.0	2DP6Q@1|root,330SE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4621905_4	1174504.AJTN02000076_gene3267	1.001e-17	90.0	2CCGS@1|root,32UCE@2|Bacteria,1V9YN@1239|Firmicutes,4HKU7@91061|Bacilli,1ZHN4@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4622808_2	944481.JAFP01000001_gene767	1.389e-43	162.0	COG2885@1|root,COG2885@2|Bacteria,1R4CA@1224|Proteobacteria,42RIU@68525|delta/epsilon subdivisions,2WNC0@28221|Deltaproteobacteria,2M7GK@213113|Desulfurellales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4892,OmpA
LZS1_k127_4622808_3	1192034.CAP_4891	3.089e-41	168.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2YWFY@29|Myxococcales	28221|Deltaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
LZS1_k127_4622808_1	525904.Tter_2454	1.278e-44	185.0	COG0277@1|root,COG0277@2|Bacteria,2NQC6@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803,ko:K11472	ko00565,ko00630,ko01100,ko01110,ko01120,ko01130,ko04146,map00565,map00630,map01100,map01110,map01120,map01130,map04146	-	R00475,R04311	RC00020,RC00042,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS1_k127_4622808_4	420246.GTNG_2314	4.664e-15	89.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,1WEGT@129337|Geobacillus	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	yqiK	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
LZS1_k127_4622808_0	1121017.AUFG01000013_gene1904	3.628e-178	571.0	COG3033@1|root,COG3033@2|Bacteria,2GKH3@201174|Actinobacteria,4FIW0@85021|Intrasporangiaceae	201174|Actinobacteria	E	Beta-eliminating lyase	tpl	-	4.1.99.1,4.1.99.2	ko:K01667,ko:K01668	ko00350,ko00380,map00350,map00380	-	R00673,R00728	RC00209,RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS1_k127_4632955_6	522306.CAP2UW1_1741	1.311e-29	136.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,1KPSW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA_2,ClpB_D2-small
LZS1_k127_4632955_10	1122244.AUGF01000069_gene1927	3.469e-06	58.0	2ED69@1|root,3372Y@2|Bacteria,1NHBV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4632955_0	330214.NIDE4293	2.683e-136	461.0	COG0001@1|root,COG0001@2|Bacteria,3J0B3@40117|Nitrospirae	40117|Nitrospirae	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_4632955_1	264732.Moth_1246	1.272e-130	424.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,42EWI@68295|Thermoanaerobacterales	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
LZS1_k127_4632955_2	1267535.KB906767_gene340	4.071e-94	340.0	COG5368@1|root,COG5368@2|Bacteria,3Y2MM@57723|Acidobacteria,2JI52@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
LZS1_k127_4632955_3	1122919.KB905604_gene4550	6.84e-92	333.0	2C4GI@1|root,2Z7IK@2|Bacteria,1TR77@1239|Firmicutes,4HC64@91061|Bacilli,26RGK@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1861)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1861
LZS1_k127_4632955_4	861299.J421_3045	5.66e-49	199.0	COG0515@1|root,COG0515@2|Bacteria,1ZUBQ@142182|Gemmatimonadetes	861299.J421_3045|-	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
LZS1_k127_4632955_8	1303518.CCALI_02647	5.465e-07	61.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	ptsN	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
LZS1_k127_4632955_9	518766.Rmar_0282	9.973e-07	61.0	2E09V@1|root,32VXB@2|Bacteria,4NY12@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4632955_5	215803.DB30_8676	4.059e-41	166.0	COG0726@1|root,COG0726@2|Bacteria,1N53V@1224|Proteobacteria,4380W@68525|delta/epsilon subdivisions,2X3AW@28221|Deltaproteobacteria,2YV6K@29|Myxococcales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS1_k127_4632955_7	880073.Calab_1394	1.944e-13	81.0	COG2067@1|root,COG2067@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	porV	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4633969_3	1384054.N790_10010	1.845e-14	79.0	COG0507@1|root,COG3410@1|root,COG0507@2|Bacteria,COG3410@2|Bacteria,1R703@1224|Proteobacteria,1RY5E@1236|Gammaproteobacteria,1X8GX@135614|Xanthomonadales	135614|Xanthomonadales	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075
LZS1_k127_4633969_2	1249480.B649_11250	1.818e-37	149.0	COG1502@1|root,COG1502@2|Bacteria,1R51A@1224|Proteobacteria,42PGS@68525|delta/epsilon subdivisions,2YNQ6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
LZS1_k127_4633969_0	272624.lpg1069	3.597e-75	262.0	COG4823@1|root,COG4823@2|Bacteria,1NJIX@1224|Proteobacteria,1RSPZ@1236|Gammaproteobacteria,1JEUG@118969|Legionellales	118969|Legionellales	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
LZS1_k127_4633969_4	227377.CBU_1788	2.733e-06	55.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
LZS1_k127_4633969_1	1385935.N836_28235	6.148e-45	169.0	COG4804@1|root,COG4804@2|Bacteria,1G1QU@1117|Cyanobacteria,1H8T8@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
LZS1_k127_4633969_5	760568.Desku_1678	0.0001932	53.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,STAS
LZS1_k127_4677031_0	671143.DAMO_0102	2.072e-61	237.0	COG4772@1|root,COG4772@2|Bacteria,2NRIP@2323|unclassified Bacteria	2|Bacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
LZS1_k127_473275_0	1123242.JH636435_gene1534	3.158e-59	223.0	COG0457@1|root,COG0457@2|Bacteria	1123242.JH636435_gene1534|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_473275_1	558884.JRGM01000038_gene1976	6.185e-57	217.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1Y3XR@135624|Aeromonadales	135624|Aeromonadales	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
LZS1_k127_473275_2	1177928.TH2_16156	7.736e-22	98.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,2TSGQ@28211|Alphaproteobacteria,2JS37@204441|Rhodospirillales	204441|Rhodospirillales	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
LZS1_k127_4760327_2	344747.PM8797T_26870	5.421e-14	84.0	COG0457@1|root,COG0457@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_4760327_0	697282.Mettu_4178	6.578e-43	165.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1XFY7@135618|Methylococcales	135618|Methylococcales	S	Haemolysin-III related	-	-	-	-	-	-	-	-	-	-	-	-	HlyIII
LZS1_k127_4760327_1	1187851.A33M_1561	2.93e-42	157.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2U5BS@28211|Alphaproteobacteria,3FE7Q@34008|Rhodovulum	28211|Alphaproteobacteria	S	DJ-1/PfpI family	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
LZS1_k127_4767780_5	1254432.SCE1572_00050	2.976e-05	46.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42PI3@68525|delta/epsilon subdivisions,2WJN3@28221|Deltaproteobacteria,2YZZD@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RluA family	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
LZS1_k127_4767780_2	909663.KI867150_gene1291	4.396e-48	192.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2MQGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	coaE	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CoaE,PseudoU_synth_2,S4
LZS1_k127_4767780_3	234267.Acid_5351	7.194e-35	145.0	COG0682@1|root,COG0682@2|Bacteria,3Y4HT@57723|Acidobacteria	57723|Acidobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS1_k127_4767780_4	648996.Theam_1094	2.265e-30	130.0	COG0682@1|root,COG0682@2|Bacteria,2G41A@200783|Aquificae	200783|Aquificae	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS1_k127_4767780_0	644282.Deba_1998	1.792e-145	473.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
LZS1_k127_4767780_1	1232410.KI421414_gene2911	3.481e-74	259.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria,43STX@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS1_k127_4776956_1	330214.NIDE1644	2.604e-05	56.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C14
LZS1_k127_4776956_0	649638.Trad_1334	7.33e-07	63.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
LZS1_k127_4816346_4	1158318.ATXC01000001_gene573	3.136e-77	267.0	COG0217@1|root,COG0217@2|Bacteria,2G3N5@200783|Aquificae	200783|Aquificae	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
LZS1_k127_4816346_8	765420.OSCT_0707	2.714e-26	123.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi,375KP@32061|Chloroflexia	32061|Chloroflexia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
LZS1_k127_4816346_10	631362.Thi970DRAFT_02203	1.344e-10	72.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
LZS1_k127_4816346_0	1125863.JAFN01000001_gene101	1.665e-132	430.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
LZS1_k127_4816346_5	864565.HMPREF0379_1445	3.419e-48	191.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,25T9S@186804|Peptostreptococcaceae	186801|Clostridia	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
LZS1_k127_4816346_2	1121468.AUBR01000027_gene2878	1.508e-96	335.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,42ETD@68295|Thermoanaerobacterales	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
LZS1_k127_4816346_6	1121396.KB892902_gene2328	4.99e-43	182.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria,2MJ8W@213118|Desulfobacterales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
LZS1_k127_4816346_1	656519.Halsa_1650	6.425e-114	378.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3WAA7@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
LZS1_k127_4816346_7	1128421.JAGA01000003_gene3091	5.141e-28	132.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS1_k127_4816346_11	926550.CLDAP_22710	4.674e-07	63.0	COG0457@1|root,COG0457@2|Bacteria	926550.CLDAP_22710|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4816346_9	404589.Anae109_4471	9.231e-18	98.0	COG0457@1|root,COG0457@2|Bacteria,1RKQQ@1224|Proteobacteria,42T9T@68525|delta/epsilon subdivisions,2WPQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_16,TPR_2,TPR_8
LZS1_k127_4816346_3	1519464.HY22_06785	2.58e-84	285.0	COG3808@1|root,COG3808@2|Bacteria,1FD6P@1090|Chlorobi	1090|Chlorobi	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
LZS1_k127_4865640_2	765869.BDW_04795	7.619e-98	327.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2MSMR@213481|Bdellovibrionales,2WIY6@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
LZS1_k127_4865640_0	880073.Calab_3212	2.821e-238	754.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
LZS1_k127_4865640_1	517418.Ctha_0693	5.019e-196	632.0	COG0004@1|root,COG0004@2|Bacteria,1FDG1@1090|Chlorobi	1090|Chlorobi	P	PFAM Rh family protein ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS1_k127_4865640_4	1123376.AUIU01000011_gene937	8.954e-35	153.0	COG2928@1|root,COG2928@2|Bacteria,3J0R2@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
LZS1_k127_4865640_3	469371.Tbis_3424	8.399e-66	243.0	COG0029@1|root,COG0157@1|root,COG0029@2|Bacteria,COG0157@2|Bacteria,2I2IJ@201174|Actinobacteria,4E18N@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS1_k127_4868100_1	767817.Desgi_4028	1.723e-59	225.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
LZS1_k127_4868100_0	1380391.JIAS01000017_gene544	6.856e-277	894.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,2JQXB@204441|Rhodospirillales	204441|Rhodospirillales	I	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
LZS1_k127_4868100_4	234267.Acid_5440	1.232e-12	82.0	COG4784@1|root,COG4784@2|Bacteria	2|Bacteria	S	Peptidase m48 ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS1_k127_4868100_3	1267535.KB906767_gene3685	1.28e-16	95.0	COG5373@1|root,COG5373@2|Bacteria,3Y44X@57723|Acidobacteria,2JHIB@204432|Acidobacteriia	204432|Acidobacteriia	NU	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
LZS1_k127_4868100_2	880072.Desac_0901	1.91e-18	91.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
LZS1_k127_4879245_1	264732.Moth_1748	2.187e-80	280.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,42FCI@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA polymerase	polX	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
LZS1_k127_4879245_0	1288494.EBAPG3_26320	7.277e-305	962.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,37225@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
LZS1_k127_4893333_2	886293.Sinac_6510	2.72e-122	419.0	COG1643@1|root,COG1643@2|Bacteria,2IX3C@203682|Planctomycetes	203682|Planctomycetes	L	ATP-dependent helicase	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
LZS1_k127_4893333_6	257313.BP1176	6.189e-45	188.0	COG3608@1|root,COG3608@2|Bacteria,1PBZ4@1224|Proteobacteria,2VMFQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	succinylglutamate desuccinylase	astE	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
LZS1_k127_4893333_7	498761.HM1_1704	3.934e-22	99.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
LZS1_k127_4893333_1	1123376.AUIU01000011_gene939	2.087e-188	606.0	COG0449@1|root,COG0449@2|Bacteria,3J0CP@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
LZS1_k127_4893333_5	1042375.AFPL01000018_gene326	7.577e-58	222.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,464QE@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390	PdxJ
LZS1_k127_4893333_3	1207063.P24_18456	1.447e-104	357.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,2JPJE@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS1_k127_4893333_4	215803.DB30_8001	8.029e-65	231.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YZJ4@29|Myxococcales	28221|Deltaproteobacteria	H	Pterin binding enzyme	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
LZS1_k127_4893333_0	1123376.AUIU01000012_gene1515	3.357e-197	631.0	COG0465@1|root,COG0465@2|Bacteria,3J0AG@40117|Nitrospirae	40117|Nitrospirae	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS1_k127_4893333_8	999413.HMPREF1094_00634	2.393e-11	64.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,3VQ8X@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
LZS1_k127_4940543_0	886293.Sinac_1713	1.831e-81	282.0	COG1301@1|root,COG1301@2|Bacteria,2IYUE@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
LZS1_k127_4953324_1	1242864.D187_000755	6.629e-98	334.0	COG0366@1|root,COG4945@1|root,COG0366@2|Bacteria,COG4945@2|Bacteria,1MU90@1224|Proteobacteria,433VR@68525|delta/epsilon subdivisions,2X3PU@28221|Deltaproteobacteria,2YWT2@29|Myxococcales	28221|Deltaproteobacteria	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
LZS1_k127_4953324_0	1121946.AUAX01000004_gene595	1.354e-141	473.0	COG0366@1|root,COG0366@2|Bacteria,2GQHX@201174|Actinobacteria,4DJ4F@85008|Micromonosporales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
LZS1_k127_4953324_2	1254432.SCE1572_11300	2.17e-69	265.0	2E55N@1|root,32ZYI@2|Bacteria,1NFET@1224|Proteobacteria,437UG@68525|delta/epsilon subdivisions,2X342@28221|Deltaproteobacteria,2YU52@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4953324_3	1231391.AMZF01000017_gene180	3.843e-15	83.0	29FE7@1|root,302BX@2|Bacteria,1NXED@1224|Proteobacteria,2W8VK@28216|Betaproteobacteria,3T7DI@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_4975657_7	1444309.JAQG01000157_gene3219	1.201e-29	125.0	COG0665@1|root,COG0665@2|Bacteria,1TRYK@1239|Firmicutes,4HAM4@91061|Bacilli,26SSE@186822|Paenibacillaceae	91061|Bacilli	E	Methyltryptophan oxidase	solA	-	1.5.3.1	ko:K00301,ko:K02846	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
LZS1_k127_4975657_11	926561.KB900617_gene2046	0.000469	52.0	COG1462@1|root,COG1462@2|Bacteria	2|Bacteria	M	curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
LZS1_k127_4975657_0	1267005.KB911257_gene930	0.0	1143.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,3N66E@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
LZS1_k127_4975657_5	1379698.RBG1_1C00001G0829	4.245e-41	172.0	COG4775@1|root,COG4775@2|Bacteria,2NRXR@2323|unclassified Bacteria	2|Bacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS1_k127_4975657_9	1125863.JAFN01000001_gene972	1.369e-25	120.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
LZS1_k127_4975657_10	1163409.UUA_10911	0.0001911	49.0	2EGSV@1|root,33AIZ@2|Bacteria,1NGPG@1224|Proteobacteria,1SGM3@1236|Gammaproteobacteria,1X8YC@135614|Xanthomonadales	135614|Xanthomonadales	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
LZS1_k127_4975657_6	436308.Nmar_0982	1.227e-32	132.0	COG1832@1|root,arCOG04227@2157|Archaea,41SMT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
LZS1_k127_4975657_4	483219.LILAB_10840	6.866e-52	198.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
LZS1_k127_4975657_8	1144275.COCOR_01631	3.59e-29	132.0	COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,42P2N@68525|delta/epsilon subdivisions,2WT6E@28221|Deltaproteobacteria,2YV8G@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,P_proprotein
LZS1_k127_4975657_1	452637.Oter_0943	2.176e-109	366.0	COG0513@1|root,COG0513@2|Bacteria,46S5M@74201|Verrucomicrobia,3K7N6@414999|Opitutae	414999|Opitutae	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
LZS1_k127_4975657_2	1278073.MYSTI_06839	2.756e-74	277.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2Z2WC@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
LZS1_k127_4975657_3	886293.Sinac_1076	7.016e-67	232.0	COG1187@1|root,COG1187@2|Bacteria,2IYUS@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS1_k127_5001540_1	882.DVU_3100	1.974e-14	83.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2MC0G@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
LZS1_k127_5001540_2	378806.STAUR_8319	2.893e-10	66.0	COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2WRCE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS1_k127_5001540_0	1125863.JAFN01000001_gene2657	4.954e-28	122.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,43BH1@68525|delta/epsilon subdivisions,2X6VI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS1_k127_5004533_4	1173025.GEI7407_0158	5.83e-10	69.0	COG5549@1|root,COG5549@2|Bacteria,1G2AK@1117|Cyanobacteria,1H6X4@1150|Oscillatoriales	1117|Cyanobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
LZS1_k127_5004533_0	644283.Micau_2845	1.321e-63	236.0	COG2242@1|root,COG2242@2|Bacteria,2IAR0@201174|Actinobacteria,4D9FM@85008|Micromonosporales	201174|Actinobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5004533_2	234267.Acid_5387	1.386e-25	123.0	COG3119@1|root,COG3119@2|Bacteria,3Y5BN@57723|Acidobacteria	57723|Acidobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS1_k127_5004533_1	1123508.JH636445_gene6495	3.74e-45	166.0	COG0607@1|root,COG0607@2|Bacteria,2IZWR@203682|Planctomycetes	203682|Planctomycetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS1_k127_5004533_3	1033743.CAES01000032_gene907	6e-17	94.0	COG0491@1|root,COG0491@2|Bacteria,1V5YS@1239|Firmicutes,4HVTY@91061|Bacilli,26V4N@186822|Paenibacillaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS1_k127_5015207_0	1121423.JONT01000007_gene592	1.194e-72	249.0	COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,248MD@186801|Clostridia,2605D@186807|Peptococcaceae	186801|Clostridia	S	PFAM peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS1_k127_5015207_1	292459.STH595	8.364e-08	62.0	2DR9X@1|root,33AUW@2|Bacteria	2|Bacteria	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
LZS1_k127_5041703_1	530564.Psta_1671	5.03e-64	231.0	COG1092@1|root,COG1092@2|Bacteria,2IYDI@203682|Planctomycetes	203682|Planctomycetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
LZS1_k127_5041703_2	435591.BDI_3807	1.08e-54	200.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,2FNEE@200643|Bacteroidia,22XKJ@171551|Porphyromonadaceae	976|Bacteroidetes	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
LZS1_k127_5041703_0	880073.Calab_1713	8.741e-162	521.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,2NP9G@2323|unclassified Bacteria	2|Bacteria	S	P-loop ATPase protein family	-	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.1.221	ko:K06958,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03019	-	-	-	APH,ATP_bind_2
LZS1_k127_5045697_1	521011.Mpal_2732	8.883e-05	52.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota	28890|Euryarchaeota	T	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS,NACHT
LZS1_k127_5045697_0	1499967.BAYZ01000069_gene1846	1.352e-128	418.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS1_k127_5103700_1	246197.MXAN_3756	3.543e-50	199.0	COG4395@1|root,COG4395@2|Bacteria,1NKJZ@1224|Proteobacteria,43793@68525|delta/epsilon subdivisions,2X2CB@28221|Deltaproteobacteria,2YYKJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
LZS1_k127_5103700_2	522306.CAP2UW1_1519	3.394e-41	156.0	COG4828@1|root,COG4828@2|Bacteria,1N984@1224|Proteobacteria,2W60I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
LZS1_k127_5103700_3	670487.Ocepr_1417	1.661e-39	162.0	COG1647@1|root,COG1647@2|Bacteria	2|Bacteria	M	Serine aminopeptidase, S33	-	-	3.1.1.1,3.1.1.85	ko:K02170,ko:K03928	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
LZS1_k127_5103700_4	660470.Theba_0837	3.791e-36	150.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2GCTF@200918|Thermotogae	200918|Thermotogae	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
LZS1_k127_5103700_0	671143.DAMO_2251	2.006e-178	566.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
LZS1_k127_5107993_0	398767.Glov_2133	1.185e-236	746.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,43U7R@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methionine synthase B12-binding module cap domain protein	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS1_k127_5107993_12	1235813.JCM10003_3778	7.355e-27	127.0	COG1502@1|root,COG1502@2|Bacteria,4NG0Z@976|Bacteroidetes,2FMNG@200643|Bacteroidia,4AN80@815|Bacteroidaceae	976|Bacteroidetes	M	Belongs to the phospholipase D family. Cardiolipin synthase subfamily	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS1_k127_5107993_1	1121430.JMLG01000008_gene1525	1.077e-171	562.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
LZS1_k127_5107993_14	1313172.YM304_18500	5.787e-13	73.0	COG0227@1|root,COG0227@2|Bacteria,2HH3N@201174|Actinobacteria,4CP3S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
LZS1_k127_5107993_13	1121468.AUBR01000025_gene2970	1.753e-25	122.0	COG1287@1|root,COG1287@2|Bacteria,1V7EF@1239|Firmicutes,24M0T@186801|Clostridia,42HQV@68295|Thermoanaerobacterales	186801|Clostridia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5107993_2	635013.TherJR_1206	2.605e-146	481.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,260Q8@186807|Peptococcaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
LZS1_k127_5107993_3	401526.TcarDRAFT_0104	6.111e-106	376.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
LZS1_k127_5107993_7	56780.SYN_01565	7.048e-75	267.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2MQCW@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
LZS1_k127_5107993_6	269799.Gmet_2352	2.168e-76	275.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS1_k127_5107993_9	1382359.JIAL01000001_gene993	1.498e-68	242.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria,2JIMV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
LZS1_k127_5107993_8	1144275.COCOR_02671	2.539e-73	256.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
LZS1_k127_5107993_11	536232.CLM_4089	2.196e-40	156.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,36IPJ@31979|Clostridiaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
LZS1_k127_5107993_10	1191523.MROS_1880	1.287e-65	237.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria	2|Bacteria	M	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
LZS1_k127_5107993_5	401526.TcarDRAFT_0093	2.13e-77	284.0	COG1044@1|root,COG1044@2|Bacteria,1TP7W@1239|Firmicutes,4H1ZV@909932|Negativicutes	909932|Negativicutes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
LZS1_k127_5107993_4	1131269.AQVV01000005_gene323	1.508e-82	304.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS1_k127_5115693_4	247490.KSU1_B0440	2.177e-44	165.0	2AVTU@1|root,31MME@2|Bacteria,2J2ZG@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5115693_5	742726.HMPREF9448_00724	6.155e-14	73.0	COG0607@1|root,COG0607@2|Bacteria,4NXGV@976|Bacteroidetes,2FUKK@200643|Bacteroidia,22YWS@171551|Porphyromonadaceae	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5115693_1	398767.Glov_0231	3.847e-115	374.0	COG1136@1|root,COG1136@2|Bacteria,1MXVW@1224|Proteobacteria,42MKV@68525|delta/epsilon subdivisions,2WJJT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_5115693_0	398767.Glov_0230	1.708e-164	552.0	COG0577@1|root,COG0577@2|Bacteria,1MVSU@1224|Proteobacteria,42NKX@68525|delta/epsilon subdivisions,2WMAW@28221|Deltaproteobacteria,43TVT@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS1_k127_5115693_3	338966.Ppro_3711	3.98e-83	284.0	COG0845@1|root,COG0845@2|Bacteria,1MV1R@1224|Proteobacteria,42PEF@68525|delta/epsilon subdivisions,2WJ93@28221|Deltaproteobacteria,43TG0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
LZS1_k127_5115693_2	243231.GSU0950	4.071e-104	351.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,42Q06@68525|delta/epsilon subdivisions,2X5KR@28221|Deltaproteobacteria,43U9R@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS1_k127_5116547_0	264462.Bd2226	0.0	1043.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2MTHN@213481|Bdellovibrionales,2WIQY@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
LZS1_k127_511833_4	1123288.SOV_7c00470	1.4e-27	116.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4H1VK@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
LZS1_k127_511833_2	1121468.AUBR01000005_gene11	1.336e-50	192.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,42FJS@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS1_k127_511833_0	72658.Bostr.0697s0118.1.p	1e-100	338.0	COG0151@1|root,KOG0237@2759|Eukaryota,37QAB@33090|Viridiplantae,3G9H5@35493|Streptophyta,3HYEJ@3699|Brassicales	35493|Streptophyta	F	Phosphoribosylformylglycinamidine cyclo-ligase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS1_k127_511833_1	518766.Rmar_1872	1.096e-60	227.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1FITI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
LZS1_k127_511833_3	742743.HMPREF9453_01732	6.296e-35	150.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H34D@909932|Negativicutes	909932|Negativicutes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
LZS1_k127_5125873_4	338963.Pcar_2126	4.442e-05	56.0	COG1538@1|root,COG1538@2|Bacteria,1MWQK@1224|Proteobacteria,42UQA@68525|delta/epsilon subdivisions,2WQXF@28221|Deltaproteobacteria,43TDQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS1_k127_5125873_2	290315.Clim_0596	4.438e-14	81.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
LZS1_k127_5125873_3	402626.Rpic_4208	1.33e-07	63.0	COG0697@1|root,COG0697@2|Bacteria,1R4M0@1224|Proteobacteria,2VMS0@28216|Betaproteobacteria,1KGQ9@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS1_k127_5125873_0	1031288.AXAA01000016_gene960	2.756e-160	518.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,36F9C@31979|Clostridiaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
LZS1_k127_5125873_1	646529.Desaci_2672	3.553e-39	153.0	COG3945@1|root,COG3945@2|Bacteria,1V3TS@1239|Firmicutes,24HUR@186801|Clostridia	186801|Clostridia	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
LZS1_k127_5129426_2	521393.JH806632_gene45	1.537e-15	91.0	COG3291@1|root,COG3291@2|Bacteria,2H200@201174|Actinobacteria,4D4TJ@85005|Actinomycetales	201174|Actinobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5129426_1	537013.CLOSTMETH_01497	1.262e-30	130.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,3WJZD@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS1_k127_5129426_0	1121346.KB899816_gene3283	7.808e-54	200.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
LZS1_k127_517262_5	103690.17131535	1.862e-39	151.0	COG2805@1|root,COG2805@2|Bacteria,1G0HI@1117|Cyanobacteria,1HKMS@1161|Nostocales	1117|Cyanobacteria	NU	PFAM Type II IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS1_k127_517262_8	518766.Rmar_2264	0.0005042	52.0	COG1316@1|root,COG1316@2|Bacteria,4P5Q5@976|Bacteroidetes,1FJHX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
LZS1_k127_517262_6	411471.SUBVAR_06424	4.839e-35	149.0	COG1057@1|root,COG1713@1|root,COG1057@2|Bacteria,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24I4S@186801|Clostridia,3WRU1@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,HD
LZS1_k127_517262_4	521674.Plim_3462	9.33e-54	203.0	COG4198@1|root,COG4198@2|Bacteria,2IX7C@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
LZS1_k127_517262_7	696369.KI912183_gene1028	6.177e-24	113.0	COG1216@1|root,COG1216@2|Bacteria,1UJRW@1239|Firmicutes,25F86@186801|Clostridia,262I4@186807|Peptococcaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_517262_3	478749.BRYFOR_06774	1.043e-83	289.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
LZS1_k127_517262_2	891968.Anamo_1556	1.103e-106	355.0	COG1052@1|root,COG1052@2|Bacteria,3TARR@508458|Synergistetes	508458|Synergistetes	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS1_k127_517262_0	330214.NIDE1289	7.007e-243	777.0	COG0058@1|root,COG0058@2|Bacteria,3J0W1@40117|Nitrospirae	40117|Nitrospirae	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
LZS1_k127_517262_1	42256.RradSPS_0714	6.935e-128	434.0	COG0210@1|root,COG0210@2|Bacteria,2GISS@201174|Actinobacteria,4CPKC@84995|Rubrobacteria	84995|Rubrobacteria	L	COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS1_k127_5187212_4	631454.N177_4099	0.000144	50.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,DUF4437
LZS1_k127_5187212_3	273057.SSO1082	6.891e-07	57.0	COG1846@1|root,arCOG03181@2157|Archaea	2157|Archaea	K	Transcriptional regulator MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
LZS1_k127_5187212_1	266117.Rxyl_0137	1.038e-18	97.0	COG0449@1|root,COG0449@2|Bacteria,2IIQ7@201174|Actinobacteria,4CQF9@84995|Rubrobacteria	84995|Rubrobacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	-
LZS1_k127_5187212_0	909663.KI867150_gene1451	5.251e-29	131.0	COG0500@1|root,COG2226@2|Bacteria,1PEBD@1224|Proteobacteria,42T7H@68525|delta/epsilon subdivisions,2WPN7@28221|Deltaproteobacteria,2MQP2@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
LZS1_k127_5187212_2	706587.Desti_2053	7.377e-09	62.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42PZH@68525|delta/epsilon subdivisions,2WJ0T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
LZS1_k127_519046_3	1209072.ALBT01000012_gene3284	1.38e-18	94.0	COG4775@1|root,COG4775@2|Bacteria,1PT0R@1224|Proteobacteria,1RPWY@1236|Gammaproteobacteria,1FI8P@10|Cellvibrio	1236|Gammaproteobacteria	M	COG4775 Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	ShlB
LZS1_k127_519046_1	880073.Calab_1130	2.97e-89	306.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
LZS1_k127_519046_5	880073.Calab_0199	3.238e-15	83.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
LZS1_k127_519046_0	391615.ABSJ01000046_gene2112	4.216e-132	436.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
LZS1_k127_519046_2	1121374.KB891585_gene1951	8.776e-87	314.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
LZS1_k127_520848_2	1239962.C943_03992	2.454e-22	104.0	COG2244@1|root,COG2244@2|Bacteria,4NDZ0@976|Bacteroidetes,47MQE@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	cap	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS1_k127_520848_3	909663.KI867150_gene1560	8.167e-16	81.0	COG5652@1|root,COG5652@2|Bacteria,1PUUC@1224|Proteobacteria,43F3B@68525|delta/epsilon subdivisions,2X381@28221|Deltaproteobacteria,2MSC7@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
LZS1_k127_520848_4	153721.MYP_2925	4.421e-08	66.0	COG1409@1|root,COG1409@2|Bacteria,4NGXX@976|Bacteroidetes,47PZR@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS1_k127_520848_0	1254432.SCE1572_17485	2.947e-53	201.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,43BF8@68525|delta/epsilon subdivisions,2X6TM@28221|Deltaproteobacteria,2YU7G@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS1_k127_520848_1	1242864.D187_004245	1.548e-24	115.0	2DX1E@1|root,342YI@2|Bacteria,1NZD7@1224|Proteobacteria,43BY2@68525|delta/epsilon subdivisions,2X78W@28221|Deltaproteobacteria,2YWTV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5216861_19	317655.Sala_0343	8.049e-08	58.0	COG0492@1|root,COG0664@1|root,COG1142@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,COG1142@2|Bacteria,1QUPD@1224|Proteobacteria,2TW3N@28211|Alphaproteobacteria,2K28S@204457|Sphingomonadales	204457|Sphingomonadales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Pyr_redox_2,Pyr_redox_3,cNMP_binding
LZS1_k127_5216861_7	1501230.ET33_31970	1.163e-70	257.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
LZS1_k127_5216861_8	370438.PTH_1596	7.576e-64	234.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,261QQ@186807|Peptococcaceae	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD
LZS1_k127_5216861_9	204669.Acid345_0035	3.937e-53	194.0	COG0313@1|root,COG0313@2|Bacteria,3Y32N@57723|Acidobacteria,2JIGR@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
LZS1_k127_5216861_13	867903.ThesuDRAFT_02412	3.122e-31	132.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WCGG@538999|Clostridiales incertae sedis	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
LZS1_k127_5216861_16	246194.CHY_2559	9.317e-24	108.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS1_k127_5216861_1	159450.NH14_09525	4.961e-170	546.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,1KBIV@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	-	-	-	-	-	-	-	-	-	-	SHMT
LZS1_k127_5216861_18	1121451.DESAM_23064	7.233e-10	72.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CS7@68525|delta/epsilon subdivisions,2X7ZW@28221|Deltaproteobacteria,2MHC1@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9,Response_reg,SBP_bac_3,sCache_3_2
LZS1_k127_5216861_6	449447.MAE_45240	8.295e-83	291.0	COG0005@1|root,COG0005@2|Bacteria,1G1F3@1117|Cyanobacteria	1117|Cyanobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
LZS1_k127_5216861_14	1219084.AP014508_gene1970	2.934e-27	127.0	COG0295@1|root,COG0295@2|Bacteria,2GD2N@200918|Thermotogae	200918|Thermotogae	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
LZS1_k127_5216861_20	331869.BAL199_05874	3.703e-05	55.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,4BQPT@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
LZS1_k127_5216861_3	471854.Dfer_4148	6.578e-154	502.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,47MHE@768503|Cytophagia	976|Bacteroidetes	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS1_k127_5216861_10	592015.HMPREF1705_00546	8.141e-51	187.0	COG0279@1|root,COG0279@2|Bacteria,3TB1U@508458|Synergistetes	508458|Synergistetes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
LZS1_k127_5216861_11	591001.Acfer_1654	2.872e-38	156.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1TSMF@1239|Firmicutes,4H2I5@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
LZS1_k127_5216861_4	580332.Slit_0253	2.855e-130	457.0	COG0457@1|root,COG1305@1|root,COG3391@1|root,COG4733@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,1R42S@1224|Proteobacteria	1224|Proteobacteria	E	fibronectin type III domain protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	-
LZS1_k127_5216861_2	1267535.KB906767_gene3899	1.28e-163	529.0	COG0064@1|root,COG0064@2|Bacteria,3Y2TJ@57723|Acidobacteria,2JI20@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
LZS1_k127_5216861_15	330214.NIDE3093	8.641e-24	116.0	COG1051@1|root,COG1051@2|Bacteria,3J1FA@40117|Nitrospirae	40117|Nitrospirae	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS1_k127_5216861_0	1125863.JAFN01000001_gene1604	9.682e-174	557.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS1_k127_5216861_12	1173023.KE650771_gene4375	1.065e-31	141.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G5G9@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
LZS1_k127_5216861_17	292563.Cyast_0683	1.986e-15	89.0	COG0721@1|root,COG0721@2|Bacteria,1G7N8@1117|Cyanobacteria	1117|Cyanobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
LZS1_k127_5216861_5	1423775.BAMN01000001_gene2549	3.51e-105	357.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,3F400@33958|Lactobacillaceae	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS1_k127_5230481_0	671143.DAMO_0682	4.431e-187	601.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
LZS1_k127_5230481_1	146922.JOFU01000027_gene1167	2.898e-05	55.0	COG0815@1|root,COG0815@2|Bacteria,2GP5I@201174|Actinobacteria	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS1_k127_5285490_2	391625.PPSIR1_13375	1.174e-43	172.0	COG3356@1|root,COG3356@2|Bacteria,1Q66U@1224|Proteobacteria,4358C@68525|delta/epsilon subdivisions,2WZJF@28221|Deltaproteobacteria,2Z29I@29|Myxococcales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
LZS1_k127_5285490_1	1242864.D187_001751	2.667e-131	444.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,42MEN@68525|delta/epsilon subdivisions,2WIYF@28221|Deltaproteobacteria,2YUH6@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
LZS1_k127_5285490_0	379066.GAU_0616	2.272e-131	446.0	COG0370@1|root,COG0370@2|Bacteria,1ZT1I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
LZS1_k127_5285490_5	670487.Ocepr_2011	0.0007487	45.0	COG1918@1|root,COG1918@2|Bacteria,1WKS4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
LZS1_k127_5285490_4	633131.TR2A62_0469	0.0001816	53.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,2UQWK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Peptidase M48	-	-	-	ko:K07387	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M48
LZS1_k127_5285490_3	518766.Rmar_0682	1.661e-16	90.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_0682|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5289092_8	1397666.RS24_00799	2.606e-78	282.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,4BS92@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	2.7.7.38,4.1.2.52	ko:K00979,ko:K02510	ko00350,ko00540,ko01100,ko01120,map00350,map00540,map01100,map01120	M00063	R01645,R01647,R03351,R11396	RC00152,RC00307,RC00572,RC00574,RC00910,RC03057	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HpcH_HpaI
LZS1_k127_5289092_7	1173026.Glo7428_1305	8.731e-84	299.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1G1R7@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
LZS1_k127_5289092_6	1173025.GEI7407_0647	1.719e-85	308.0	COG1132@1|root,COG1132@2|Bacteria,1G02Q@1117|Cyanobacteria,1H8KQ@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS1_k127_5289092_4	768706.Desor_4902	6.786e-108	375.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,261AB@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS1_k127_5289092_0	439235.Dalk_0629	8.739e-221	719.0	COG0001@1|root,COG1861@1|root,COG0001@2|Bacteria,COG1861@2|Bacteria,1MUY5@1224|Proteobacteria,42NVU@68525|delta/epsilon subdivisions,2WMH6@28221|Deltaproteobacteria,2MNBA@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.111,5.4.3.8	ko:K01845,ko:K07257,ko:K21585	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272,R11607	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
LZS1_k127_5289092_13	706587.Desti_2826	1.397e-65	236.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,42SMJ@68525|delta/epsilon subdivisions,2WPNK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS1_k127_5289092_3	941449.dsx2_1108	9.673e-130	422.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,42ME3@68525|delta/epsilon subdivisions,2WJXH@28221|Deltaproteobacteria,2M9ME@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM N-acetylneuraminic acid synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
LZS1_k127_5289092_18	1121438.JNJA01000011_gene1823	6.366e-47	181.0	COG1247@1|root,COG3980@1|root,COG1247@2|Bacteria,COG3980@2|Bacteria,1Q330@1224|Proteobacteria,42P4J@68525|delta/epsilon subdivisions,2WIM2@28221|Deltaproteobacteria,2MBKT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Glyco_tran_28_C
LZS1_k127_5289092_2	1121456.ATVA01000015_gene2476	1.123e-138	448.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42M4P@68525|delta/epsilon subdivisions,2WIKX@28221|Deltaproteobacteria,2M9KK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Polysaccharide biosynthesis protein	pseB	-	4.2.1.115	ko:K15894	ko00520,map00520	-	R09697	RC02609	ko00000,ko00001,ko01000	-	-	-	Polysacc_synt_2
LZS1_k127_5289092_20	1229780.BN381_50006	4.509e-41	166.0	2E9V3@1|root,3340Y@2|Bacteria,2HDUI@201174|Actinobacteria	201174|Actinobacteria	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
LZS1_k127_5289092_23	1121936.AUHI01000007_gene2340	1.737e-23	108.0	COG1670@1|root,COG1670@2|Bacteria,1V7UX@1239|Firmicutes,4HJPE@91061|Bacilli	91061|Bacilli	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Acetyltransf_4
LZS1_k127_5289092_9	237368.SCABRO_00436	6.18e-75	273.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS1_k127_5289092_11	204773.HEAR1128	5.199e-71	262.0	28NEE@1|root,2ZBGY@2|Bacteria,1QW5M@1224|Proteobacteria,2VTKX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5289092_10	1033743.CAES01000007_gene2016	2.19e-72	258.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,26VB1@186822|Paenibacillaceae	91061|Bacilli	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS1_k127_5289092_14	1380394.JADL01000001_gene1957	1.059e-61	230.0	COG0111@1|root,COG0111@2|Bacteria,1R5FD@1224|Proteobacteria,2U0C0@28211|Alphaproteobacteria,2JSER@204441|Rhodospirillales	204441|Rhodospirillales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
LZS1_k127_5289092_19	1047013.AQSP01000144_gene804	1.679e-44	173.0	COG1212@1|root,COG1212@2|Bacteria,2NP8R@2323|unclassified Bacteria	2|Bacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
LZS1_k127_5289092_5	1131269.AQVV01000013_gene1726	1.389e-103	356.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS1_k127_5289092_17	565033.GACE_0916	1.492e-50	197.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota,245XG@183980|Archaeoglobi	183980|Archaeoglobi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS1_k127_5289092_22	667632.KB890185_gene480	7.894e-29	128.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,2WEQI@28216|Betaproteobacteria,1KHZ5@119060|Burkholderiaceae	28216|Betaproteobacteria	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD,Epimerase
LZS1_k127_5289092_12	357808.RoseRS_4447	2.138e-69	249.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi,3768U@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
LZS1_k127_5289092_21	420662.Mpe_A0718	1.846e-34	141.0	COG2755@1|root,COG2755@2|Bacteria,1RBFJ@1224|Proteobacteria,2VQYX@28216|Betaproteobacteria	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS1_k127_5289092_15	316056.RPC_4212	1.408e-57	212.0	COG0463@1|root,COG0463@2|Bacteria,1QYW1@1224|Proteobacteria,2U541@28211|Alphaproteobacteria,3JVD3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_5289092_24	1410608.JNKX01000011_gene309	1.169e-22	106.0	COG0110@1|root,COG0110@2|Bacteria,4NNQ5@976|Bacteroidetes,2G32E@200643|Bacteroidia,4AW8I@815|Bacteroidaceae	976|Bacteroidetes	S	Hexapeptide repeat of succinyl-transferase	-	-	-	ko:K08280	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
LZS1_k127_5289092_27	1265505.ATUG01000001_gene3758	3.174e-10	72.0	294XI@1|root,2ZSAH@2|Bacteria,1RDZH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
LZS1_k127_5289092_29	1385521.N803_01035	1.541e-07	64.0	COG3307@1|root,COG3307@2|Bacteria,2HXGD@201174|Actinobacteria,4FGJU@85021|Intrasporangiaceae	201174|Actinobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS1_k127_5289092_28	1403819.BATR01000053_gene1635	3.43e-09	70.0	COG1083@1|root,COG1083@2|Bacteria	2|Bacteria	M	cytidylyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
LZS1_k127_5289092_25	1120950.KB892801_gene1666	1.521e-17	97.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4DSH1@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS1_k127_5289092_1	1282360.ABAC460_19840	2.632e-182	586.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria	1224|Proteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS1_k127_5289092_16	583355.Caka_1913	7.639e-53	192.0	COG2199@1|root,COG3706@2|Bacteria,46ST0@74201|Verrucomicrobia,3K80V@414999|Opitutae	414999|Opitutae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_5289092_26	1123372.AUIT01000022_gene985	2.014e-15	77.0	COG1189@1|root,COG1189@2|Bacteria,2GGSK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
LZS1_k127_5290966_1	330214.NIDE3611	5.887e-53	206.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
LZS1_k127_5290966_2	290397.Adeh_4177	9.451e-47	181.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2X6EH@28221|Deltaproteobacteria,2Z3AS@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
LZS1_k127_5290966_0	755732.Fluta_0646	4.846e-108	353.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,1HXRF@117743|Flavobacteriia,2PAK2@246874|Cryomorphaceae	976|Bacteroidetes	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
LZS1_k127_5291810_0	751945.Theos_0493	2.384e-38	149.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS1_k127_5291810_1	1227453.C444_04177	4.343e-06	58.0	COG4427@1|root,arCOG09080@2157|Archaea,2XWG2@28890|Euryarchaeota,23TPM@183963|Halobacteria	183963|Halobacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
LZS1_k127_5313618_1	1469245.JFBG01000054_gene2111	1.864e-65	239.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
LZS1_k127_5313618_3	479437.Elen_2547	7.203e-50	187.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,4CVUU@84998|Coriobacteriia	84998|Coriobacteriia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II,PTS_EIIB
LZS1_k127_5313618_0	370438.PTH_1628	3.907e-85	298.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,260ZU@186807|Peptococcaceae	186801|Clostridia	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
LZS1_k127_5313618_2	1161401.ASJA01000007_gene2098	2.383e-62	220.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria,43XHM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS1_k127_5313618_4	945713.IALB_2378	1.601e-33	141.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
LZS1_k127_5313618_5	518766.Rmar_1047	5.086e-08	61.0	COG0134@1|root,COG0134@2|Bacteria,4NFJT@976|Bacteroidetes,1FJ8Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Indole-3-glycerol phosphate synthase	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
LZS1_k127_5314761_2	1384054.N790_09610	4.051e-75	259.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	3.4.16.4	ko:K07258,ko:K07262	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
LZS1_k127_5314761_3	1123261.AXDW01000009_gene106	4.659e-75	273.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria,1XA50@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87
LZS1_k127_5314761_12	521096.Tpau_0076	3.805e-08	66.0	COG1807@1|root,COG1807@2|Bacteria,2H2FK@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5314761_5	1329516.JPST01000012_gene224	1.622e-41	163.0	COG1028@1|root,COG1028@2|Bacteria,1V0TV@1239|Firmicutes,4HF8Q@91061|Bacilli	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS1_k127_5314761_8	1123277.KB893176_gene3838	4.329e-33	144.0	COG2230@1|root,COG2230@2|Bacteria,4PNB2@976|Bacteroidetes,47RD3@768503|Cytophagia	976|Bacteroidetes	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
LZS1_k127_5314761_1	589865.DaAHT2_0378	1.98e-169	541.0	COG4976@1|root,COG4976@2|Bacteria,1QW8Z@1224|Proteobacteria,43D5S@68525|delta/epsilon subdivisions,2X8CH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
LZS1_k127_5314761_9	589865.DaAHT2_0377	6.029e-29	132.0	COG2140@1|root,COG2140@2|Bacteria,1QZX3@1224|Proteobacteria	1224|Proteobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5314761_10	765177.Desmu_0414	1.226e-22	110.0	COG0463@1|root,arCOG00894@2157|Archaea,2XPZS@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS1_k127_5314761_11	1198114.AciX9_3703	6.89e-11	76.0	COG1807@1|root,COG1807@2|Bacteria,3Y46U@57723|Acidobacteria,2JJ34@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_5314761_7	1121413.JMKT01000014_gene2489	8.35e-37	141.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MC2A@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS1_k127_5314761_0	96561.Dole_2573	3.167e-170	569.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2MIIB@213118|Desulfobacterales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS1_k127_5314761_4	1379698.RBG1_1C00001G1850	6.73e-53	198.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS1_k127_5314761_6	1122918.KB907283_gene1166	6.217e-37	148.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,26WY5@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08510	CoaE
LZS1_k127_5325002_5	264462.Bd0160	9.237e-37	158.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2MSQ6@213481|Bdellovibrionales,2WIXF@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
LZS1_k127_5325002_0	945713.IALB_3149	1.473e-128	429.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
LZS1_k127_5325002_4	290397.Adeh_2532	6.927e-60	228.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2YWFY@29|Myxococcales	28221|Deltaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
LZS1_k127_5325002_2	243231.GSU2569	3.91e-84	299.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
LZS1_k127_5325002_1	338963.Pcar_1860	1.494e-96	329.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,43S8G@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-2	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,Molybdopterin,Molydop_binding
LZS1_k127_5325002_6	1382359.JIAL01000001_gene1939	7.316e-25	113.0	COG1360@1|root,COG1360@2|Bacteria,3Y4KZ@57723|Acidobacteria,2JJ8N@204432|Acidobacteriia	204432|Acidobacteriia	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
LZS1_k127_5325002_3	525897.Dbac_2738	1.997e-63	227.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria,2M7ZH@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
LZS1_k127_5325002_9	635013.TherJR_1532	2.226e-10	66.0	COG1582@1|root,COG1582@2|Bacteria,1VKHB@1239|Firmicutes,24RWI@186801|Clostridia,2633P@186807|Peptococcaceae	186801|Clostridia	N	protein possibly involved in motility	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
LZS1_k127_5325002_8	667014.Thein_1813	1.326e-21	111.0	COG1536@1|root,COG1536@2|Bacteria,2GGYT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	N	flagellar motor switch protein FliG	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
LZS1_k127_5325002_7	1379698.RBG1_1C00001G1334	3.784e-22	111.0	COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria	2|Bacteria	I	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
LZS1_k127_5340628_0	1379698.RBG1_1C00001G1152	2.969e-92	318.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
LZS1_k127_5340628_1	1454004.AW11_01898	1.895e-15	78.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,1KQ4J@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
LZS1_k127_5366859_2	290397.Adeh_4291	3.181e-48	183.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2WJC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS1_k127_5366859_0	485918.Cpin_1132	6.507e-83	289.0	COG0657@1|root,COG0657@2|Bacteria,4NKR4@976|Bacteroidetes,1IQP2@117747|Sphingobacteriia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
LZS1_k127_5366859_3	713587.THITH_04115	4.076e-27	116.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,1RRKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
LZS1_k127_5366859_4	1056816.JAFQ01000004_gene4140	9.754e-13	74.0	COG1764@1|root,COG1764@2|Bacteria,2IHT2@201174|Actinobacteria,4G1JJ@85025|Nocardiaceae	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
LZS1_k127_5366859_1	55529.EKX48600	3.913e-78	273.0	COG0308@1|root,KOG1046@2759|Eukaryota	2759|Eukaryota	E	metalloaminopeptidase activity	APE2	GO:0000322,GO:0000323,GO:0000324,GO:0000328,GO:0001666,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005768,GO:0005770,GO:0005771,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006073,GO:0006091,GO:0006112,GO:0006508,GO:0006518,GO:0006807,GO:0006810,GO:0006950,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009277,GO:0009628,GO:0009914,GO:0009926,GO:0009987,GO:0010013,GO:0010467,GO:0010817,GO:0012505,GO:0015980,GO:0016020,GO:0016485,GO:0016787,GO:0017171,GO:0019538,GO:0030287,GO:0030312,GO:0031090,GO:0031406,GO:0031410,GO:0031974,GO:0031982,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033554,GO:0034613,GO:0034641,GO:0036094,GO:0036293,GO:0036294,GO:0042221,GO:0042277,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043171,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043603,GO:0044042,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051716,GO:0055114,GO:0060918,GO:0061957,GO:0065007,GO:0065008,GO:0070006,GO:0070011,GO:0070013,GO:0070482,GO:0070727,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0071944,GO:0072665,GO:0097159,GO:0097708,GO:0120113,GO:0140096,GO:1901564,GO:1901565,GO:1901575	1.1.3.20,3.4.11.2	ko:K01256,ko:K07874,ko:K08776,ko:K13721,ko:K17756	ko00480,ko01100,ko05134,map00480,map01100,map05134	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko04031,ko04131,ko04147	-	-	-	ERAP1_C,Peptidase_M1
LZS1_k127_5377792_0	1125863.JAFN01000001_gene2792	0.0	1241.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2WKKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
LZS1_k127_5388827_1	439235.Dalk_1768	4.355e-34	142.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MIZH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS1_k127_5388827_0	667014.Thein_0824	5.69e-40	164.0	COG2230@1|root,COG2230@2|Bacteria,2GID4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS1_k127_543821_3	1121447.JONL01000003_gene3293	4.604e-83	291.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
LZS1_k127_543821_6	1267534.KB906754_gene3020	7.348e-37	152.0	COG1560@1|root,COG1560@2|Bacteria,3Y2RW@57723|Acidobacteria,2JIMS@204432|Acidobacteriia	204432|Acidobacteriia	M	lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
LZS1_k127_543821_2	322710.Avin_11590	2.487e-98	343.0	COG3129@1|root,COG3129@2|Bacteria,1MUI4@1224|Proteobacteria,1RMVA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the adenine in position 1618 of 23S rRNA	rlmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.181	ko:K06970	-	-	R07232	RC00003,RC00335	ko00000,ko01000,ko03009	-	-	-	Methyltransf_10
LZS1_k127_543821_8	1157708.KB907450_gene6377	3.132e-22	103.0	COG2885@1|root,COG2885@2|Bacteria,1R4CA@1224|Proteobacteria,2VSK7@28216|Betaproteobacteria	28216|Betaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4892,OmpA
LZS1_k127_543821_1	497964.CfE428DRAFT_0142	3.655e-120	394.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS1_k127_543821_0	867845.KI911784_gene3137	2.351e-135	438.0	COG0330@1|root,COG0330@2|Bacteria,2GAMW@200795|Chloroflexi,3772P@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS1_k127_543821_7	1089550.ATTH01000001_gene2106	3.985e-36	157.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1FIXN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycogen debranching enzyme, glucanotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
LZS1_k127_543821_4	1509405.GV67_23215	1.069e-70	262.0	COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2TRZX@28211|Alphaproteobacteria,4BBVB@82115|Rhizobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS1_k127_543821_5	316067.Geob_2601	5.109e-43	178.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,437BB@68525|delta/epsilon subdivisions,2X2G7@28221|Deltaproteobacteria,43V98@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS1_k127_5450411_3	357804.Ping_1308	8.397e-15	83.0	COG4395@1|root,COG4395@2|Bacteria,1NKJZ@1224|Proteobacteria,1SU45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5450411_1	1379698.RBG1_1C00001G0657	1.257e-42	168.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	Z012_09115	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
LZS1_k127_5450411_2	1031711.RSPO_c02188	8.825e-28	117.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,2VU3I@28216|Betaproteobacteria,1K8HB@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
LZS1_k127_5450411_0	525903.Taci_0821	1.021e-89	304.0	COG0216@1|root,COG0216@2|Bacteria,3TA5F@508458|Synergistetes	508458|Synergistetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS1_k127_5472601_3	1121918.ARWE01000001_gene3411	5.901e-21	109.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,42SG5@68525|delta/epsilon subdivisions,2WNPI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM nuclease (SNase domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,Excalibur,SNase
LZS1_k127_5472601_4	690850.Desaf_1935	5.665e-17	96.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,42SG5@68525|delta/epsilon subdivisions,2WNPI@28221|Deltaproteobacteria,2MCRU@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM nuclease (SNase domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,Excalibur,SNase
LZS1_k127_5472601_1	398512.JQKC01000030_gene4385	7.191e-62	224.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHXD@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
LZS1_k127_5472601_0	1173028.ANKO01000195_gene5992	8.077e-67	253.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HH3F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
LZS1_k127_5472601_2	118163.Ple7327_4529	3.212e-47	180.0	COG0745@1|root,COG0745@2|Bacteria,1G51F@1117|Cyanobacteria,3VMN0@52604|Pleurocapsales	1117|Cyanobacteria	KT	PFAM Response regulator receiver domain	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
LZS1_k127_5472601_5	502025.Hoch_6692	1.176e-06	56.0	COG2823@1|root,COG2823@2|Bacteria,1PY9X@1224|Proteobacteria,42YAD@68525|delta/epsilon subdivisions,2WU1C@28221|Deltaproteobacteria,2Z27W@29|Myxococcales	28221|Deltaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS1_k127_5497004_0	861299.J421_2138	1.026e-196	630.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	pucD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS1_k127_5497004_8	1192034.CAP_0075	8.459e-43	173.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,4309M@68525|delta/epsilon subdivisions,2WV9K@28221|Deltaproteobacteria,2Z13I@29|Myxococcales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
LZS1_k127_5497004_5	502025.Hoch_5969	8.257e-51	192.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,42R7J@68525|delta/epsilon subdivisions,2WMT4@28221|Deltaproteobacteria,2Z0Y2@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS1_k127_5497004_1	378806.STAUR_1028	2.087e-175	561.0	COG2301@1|root,COG2301@2|Bacteria,1R7U2@1224|Proteobacteria,437FH@68525|delta/epsilon subdivisions,2X2N4@28221|Deltaproteobacteria,2YTXN@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
LZS1_k127_5497004_10	1045004.OKIT_1258	8.2e-21	100.0	COG0454@1|root,COG0456@2|Bacteria,1VI1S@1239|Firmicutes,4HRN1@91061|Bacilli	91061|Bacilli	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
LZS1_k127_5497004_9	1137799.GZ78_19090	4.623e-30	130.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,1SC8E@1236|Gammaproteobacteria,1XQZU@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	-	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
LZS1_k127_5497004_6	483219.LILAB_16830	5.743e-50	189.0	COG3195@1|root,COG3195@2|Bacteria,1RIGR@1224|Proteobacteria,438E6@68525|delta/epsilon subdivisions,2X3PB@28221|Deltaproteobacteria,2YWR6@29|Myxococcales	28221|Deltaproteobacteria	S	OHCU decarboxylase	-	-	4.1.1.97	ko:K16840	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06604	RC01551	ko00000,ko00001,ko00002,ko01000	-	-	-	OHCU_decarbox
LZS1_k127_5497004_4	448385.sce5877	5.088e-118	391.0	COG3195@1|root,COG4266@1|root,COG3195@2|Bacteria,COG4266@2|Bacteria,1MXJK@1224|Proteobacteria,42YE0@68525|delta/epsilon subdivisions,2X30N@28221|Deltaproteobacteria,2YTWS@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the allantoicase family	alc	-	3.5.3.4	ko:K01477	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02422	RC00379,RC00712	ko00000,ko00001,ko00002,ko01000	-	-	-	Allantoicase,OHCU_decarbox
LZS1_k127_5497004_2	215803.DB30_1349	4.954e-155	502.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,42RF2@68525|delta/epsilon subdivisions,2WP05@28221|Deltaproteobacteria,2YWCM@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	allB	-	3.5.2.5	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R02425	RC00680	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS1_k127_5497004_11	414996.IL38_23585	3.197e-07	60.0	COG2068@1|root,COG2068@2|Bacteria,2GK5R@201174|Actinobacteria,4096T@622450|Actinopolysporales	201174|Actinobacteria	S	MobA-like NTP transferase domain	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS1_k127_5497004_7	378806.STAUR_1414	3.002e-43	168.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,42QUY@68525|delta/epsilon subdivisions,2WMVP@28221|Deltaproteobacteria,2Z3DA@29|Myxococcales	28221|Deltaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
LZS1_k127_5497004_3	158189.SpiBuddy_1815	1.646e-139	463.0	COG0402@1|root,COG0402@2|Bacteria,2J6KS@203691|Spirochaetes	203691|Spirochaetes	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS1_k127_5503533_0	1254432.SCE1572_14985	1.1e-99	336.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2WKK6@28221|Deltaproteobacteria,2YTTN@29|Myxococcales	28221|Deltaproteobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
LZS1_k127_5503533_1	485915.Dret_1874	2.981e-87	307.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2M7XK@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS1_k127_5503533_2	478741.JAFS01000002_gene314	7.845e-51	197.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,37GI5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
LZS1_k127_5503533_6	383372.Rcas_0215	5.876e-05	56.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2G9QS@200795|Chloroflexi	200795|Chloroflexi	T	SMART RNA-processing protein HAT helix repeating-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,TPR_16,TPR_19,TPR_8
LZS1_k127_5503533_3	311424.DhcVS_266	1.229e-41	176.0	COG1752@1|root,COG1752@2|Bacteria,2G70S@200795|Chloroflexi,34D57@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS1_k127_5503533_4	661478.OP10G_0769	1.652e-05	58.0	COG1538@1|root,COG1538@2|Bacteria	661478.OP10G_0769|-	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5503533_5	1380355.JNIJ01000043_gene5108	4.455e-05	53.0	COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1QW6N@1224|Proteobacteria,2TWQ3@28211|Alphaproteobacteria,3JU8D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,dCache_1
LZS1_k127_5510121_5	1268072.PSAB_11255	2.193e-35	149.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4IQKZ@91061|Bacilli,276F6@186822|Paenibacillaceae	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
LZS1_k127_5510121_6	1131269.AQVV01000011_gene2520	2.258e-29	120.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
LZS1_k127_5510121_0	945713.IALB_2618	2.83e-175	566.0	COG3033@1|root,COG3033@2|Bacteria	2|Bacteria	E	tryptophanase activity	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS1_k127_5510121_4	886293.Sinac_1778	4.33e-38	166.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,2IXA1@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA
LZS1_k127_5510121_1	1051632.TPY_1594	4.692e-138	471.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia	186801|Clostridia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS1_k127_5510121_3	1265505.ATUG01000001_gene3898	6.029e-57	214.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2WJ1F@28221|Deltaproteobacteria,2MHQX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
LZS1_k127_5510121_2	123214.PERMA_0986	3.941e-95	325.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G5H0@200783|Aquificae	200783|Aquificae	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD
LZS1_k127_5510121_7	331678.Cphamn1_0814	5.467e-15	81.0	2E3B5@1|root,32YAP@2|Bacteria,1FE8N@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
LZS1_k127_5535570_1	913848.AELK01000007_gene1112	7.145e-62	227.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,3F4EC@33958|Lactobacillaceae	91061|Bacilli	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
LZS1_k127_5535570_0	118173.KB235910_gene5084	1.817e-93	325.0	COG0389@1|root,COG0389@2|Bacteria,1G07F@1117|Cyanobacteria,1H6YS@1150|Oscillatoriales	1117|Cyanobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C
LZS1_k127_5535570_4	314262.MED193_12443	5.292e-18	86.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
LZS1_k127_5535570_2	913865.DOT_1718	7.733e-38	147.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,2626H@186807|Peptococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
LZS1_k127_5535570_3	290397.Adeh_3960	6.857e-19	95.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2YVZ3@29|Myxococcales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
LZS1_k127_5535570_6	765913.ThidrDRAFT_0323	6.465e-07	63.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,1RPX3@1236|Gammaproteobacteria,1WWF8@135613|Chromatiales	135613|Chromatiales	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
LZS1_k127_553957_0	518766.Rmar_2052	2.914e-113	389.0	COG1198@1|root,COG1198@2|Bacteria,4NFHB@976|Bacteroidetes,1FJ34@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
LZS1_k127_5568132_4	65071.PYU1_T005140	2.342e-51	195.0	COG1028@1|root,KOG1201@2759|Eukaryota,1MENB@121069|Pythiales	2759|Eukaryota	Q	Retinol dehydrogenase. Source PGD	DHRS3	GO:0000166,GO:0001501,GO:0001523,GO:0001750,GO:0003007,GO:0003008,GO:0003151,GO:0003205,GO:0003206,GO:0003279,GO:0003674,GO:0003824,GO:0004033,GO:0004745,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0005929,GO:0006066,GO:0006091,GO:0006629,GO:0006720,GO:0006721,GO:0007275,GO:0007507,GO:0007600,GO:0007601,GO:0008106,GO:0008150,GO:0008152,GO:0009055,GO:0009653,GO:0009887,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0010817,GO:0012505,GO:0016020,GO:0016101,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0023051,GO:0023057,GO:0030278,GO:0031090,GO:0031253,GO:0031984,GO:0032501,GO:0032502,GO:0034308,GO:0034754,GO:0036094,GO:0042175,GO:0042445,GO:0042572,GO:0042622,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044441,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0048385,GO:0048387,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048705,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050877,GO:0050953,GO:0051239,GO:0052650,GO:0055114,GO:0060021,GO:0060170,GO:0060348,GO:0060349,GO:0060411,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0072359,GO:0097159,GO:0097458,GO:0097730,GO:0097731,GO:0097733,GO:0098588,GO:0098590,GO:0098827,GO:0120025,GO:0120038,GO:1901265,GO:1901363,GO:1901615	1.1.1.105,1.1.1.300	ko:K11146,ko:K15734	ko00830,ko01100,map00830,map01100	-	R02124,R08379	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
LZS1_k127_5568132_0	671143.DAMO_0332	2.075e-145	471.0	COG0014@1|root,COG0014@2|Bacteria,2NQM3@2323|unclassified Bacteria	2|Bacteria	E	Aldehyde dehydrogenase family	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0293,iYO844.BSU13130	Aldedh
LZS1_k127_5568132_2	671143.DAMO_0331	8.55e-102	342.0	COG0263@1|root,COG0263@2|Bacteria,2NQMJ@2323|unclassified Bacteria	2|Bacteria	E	PUA domain	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
LZS1_k127_5568132_7	671143.DAMO_2862	1.342e-33	143.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	def2	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
LZS1_k127_5568132_1	497964.CfE428DRAFT_0801	4.313e-105	350.0	COG4586@1|root,COG4586@2|Bacteria,46TXF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_5568132_6	497964.CfE428DRAFT_2347	5.409e-34	149.0	COG4587@1|root,COG4587@2|Bacteria,46VAG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
LZS1_k127_5568132_8	290397.Adeh_0400	5.96e-13	82.0	COG3694@1|root,COG3694@2|Bacteria,1NAPK@1224|Proteobacteria,42X7R@68525|delta/epsilon subdivisions,2WSZA@28221|Deltaproteobacteria,2YVA3@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
LZS1_k127_5568132_3	429009.Adeg_0661	2.939e-76	274.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,42EMU@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS1_k127_5568132_5	670487.Ocepr_1937	3.353e-35	139.0	COG0193@1|root,COG0193@2|Bacteria,1WJCK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
LZS1_k127_5592187_10	398527.Bphyt_5508	1.717e-20	101.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VKA6@28216|Betaproteobacteria,1KFDC@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS1_k127_5592187_6	709797.CSIRO_1019	2.125e-41	172.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,3JQPP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
LZS1_k127_5592187_2	292415.Tbd_0220	2.665e-107	355.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,1KSW1@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF808)	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
LZS1_k127_5592187_7	765869.BDW_14195	1.403e-32	136.0	2F91Y@1|root,341DM@2|Bacteria,1NXJ8@1224|Proteobacteria,430BR@68525|delta/epsilon subdivisions,2MTAE@213481|Bdellovibrionales,2WW54@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5592187_0	1237149.C900_05420	6.024e-234	734.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,47JZ2@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
LZS1_k127_5592187_9	326424.FRAAL2042	2.169e-22	110.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
LZS1_k127_5592187_1	234267.Acid_1593	8.475e-136	472.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_1593|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5592187_5	1121013.P873_01740	3e-43	178.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1X623@135614|Xanthomonadales	135614|Xanthomonadales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_5592187_8	243231.GSU0677	1.471e-29	133.0	COG4591@1|root,COG4591@2|Bacteria,1QXN9@1224|Proteobacteria,43C49@68525|delta/epsilon subdivisions,2X7EQ@28221|Deltaproteobacteria,43U8U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS1_k127_5592187_3	1496688.ER33_10300	4.689e-57	203.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Raf kinase inhibitor-like protein, YbhB YbcL family	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
LZS1_k127_5592187_11	589865.DaAHT2_0084	3.628e-16	83.0	COG0347@1|root,COG0347@2|Bacteria,1RF4Q@1224|Proteobacteria,42Y29@68525|delta/epsilon subdivisions,2X0JP@28221|Deltaproteobacteria,2MP9F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5592187_4	330214.NIDE0322	3.428e-45	168.0	COG4398@1|root,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
LZS1_k127_5606405_1	1206732.BAGD01000076_gene3094	6.165e-06	53.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria,4FW1V@85025|Nocardiaceae	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS1_k127_5606405_0	1267533.KB906733_gene3498	4.276e-09	61.0	arCOG12677@1|root,2ZCT8@2|Bacteria,3Y95Y@57723|Acidobacteria,2JNVX@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5606405_2	1283300.ATXB01000001_gene1737	1.088e-05	51.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
LZS1_k127_5606405_3	1499502.EV12_0982	1.247e-05	56.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1MM8U@1212|Prochloraceae	1117|Cyanobacteria	O	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_8,Trypsin_2
LZS1_k127_5621295_1	1384054.N790_03075	1.248e-82	294.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1X38D@135614|Xanthomonadales	135614|Xanthomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS1_k127_5621295_2	1500893.JQNB01000001_gene2383	1.715e-75	261.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,1RYRE@1236|Gammaproteobacteria,1X4DI@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
LZS1_k127_5621295_3	1201288.M900_1599	5.663e-29	123.0	COG1595@1|root,COG1595@2|Bacteria,1RI7C@1224|Proteobacteria,42XJU@68525|delta/epsilon subdivisions,2WT13@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS1_k127_5621295_0	886293.Sinac_3668	1.284e-92	320.0	COG0534@1|root,COG0534@2|Bacteria,2IX5Q@203682|Planctomycetes	203682|Planctomycetes	V	COG0534 Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
LZS1_k127_5621295_4	575540.Isop_3345	6.354e-07	60.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
LZS1_k127_5662947_0	264462.Bd1874	6.377e-77	270.0	COG0501@1|root,COG0501@2|Bacteria,1NF76@1224|Proteobacteria,42WFB@68525|delta/epsilon subdivisions,2MTHK@213481|Bdellovibrionales,2WSAI@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS1_k127_5682513_4	639030.JHVA01000001_gene3124	4.45e-32	136.0	COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria,2JHXV@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
LZS1_k127_5682513_2	290397.Adeh_2901	1.353e-40	167.0	COG0662@1|root,COG0662@2|Bacteria,1N1T5@1224|Proteobacteria	1224|Proteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS1_k127_5682513_0	435908.IDSA_00035	6.867e-127	417.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,1RNVI@1236|Gammaproteobacteria,2QFDG@267893|Idiomarinaceae	1236|Gammaproteobacteria	F	Adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
LZS1_k127_5682513_1	1382359.JIAL01000001_gene1215	1.466e-110	371.0	COG1819@1|root,COG1819@2|Bacteria,3Y3H9@57723|Acidobacteria,2JKTT@204432|Acidobacteriia	204432|Acidobacteriia	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
LZS1_k127_5682513_3	748449.Halha_0470	1.366e-36	154.0	COG0366@1|root,COG4945@1|root,COG5492@1|root,COG0366@2|Bacteria,COG4945@2|Bacteria,COG5492@2|Bacteria,1TSVI@1239|Firmicutes,24DTG@186801|Clostridia,3WC20@53433|Halanaerobiales	186801|Clostridia	G	Alpha amylase catalytic	-	-	2.4.1.19	ko:K00701	ko00500,map00500	-	R11260	-	ko00000,ko00001,ko01000	-	CBM20,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_20,TIG
LZS1_k127_5744043_6	7739.XP_002593897.1	2.241e-106	387.0	COG1132@1|root,KOG0055@2759|Eukaryota,38E88@33154|Opisthokonta,3B958@33208|Metazoa,3CVKH@33213|Bilateria,483MS@7711|Chordata	33208|Metazoa	Q	phosphatidylcholine-translocating ATPase activity	ABCB1	GO:0000086,GO:0000139,GO:0000166,GO:0000278,GO:0001101,GO:0001654,GO:0003008,GO:0003674,GO:0003824,GO:0004012,GO:0005215,GO:0005319,GO:0005488,GO:0005524,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005794,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0005903,GO:0005911,GO:0005912,GO:0005924,GO:0005925,GO:0006629,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006869,GO:0006996,GO:0007049,GO:0007275,GO:0007423,GO:0007586,GO:0008144,GO:0008150,GO:0008152,GO:0008283,GO:0008525,GO:0008559,GO:0008643,GO:0009410,GO:0009719,GO:0009725,GO:0009914,GO:0009986,GO:0009987,GO:0010033,GO:0010359,GO:0010817,GO:0010876,GO:0010941,GO:0012505,GO:0014070,GO:0015238,GO:0015399,GO:0015405,GO:0015562,GO:0015629,GO:0015695,GO:0015696,GO:0015711,GO:0015718,GO:0015748,GO:0015849,GO:0015893,GO:0015914,GO:0016020,GO:0016021,GO:0016043,GO:0016324,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019216,GO:0019222,GO:0019915,GO:0022402,GO:0022600,GO:0022804,GO:0022857,GO:0022898,GO:0030054,GO:0030055,GO:0030154,GO:0030554,GO:0031090,GO:0031224,GO:0031226,GO:0031253,GO:0031410,GO:0031526,GO:0031960,GO:0031974,GO:0031981,GO:0031982,GO:0031984,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032782,GO:0032879,GO:0033036,GO:0033231,GO:0033993,GO:0034204,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035620,GO:0035627,GO:0035633,GO:0035639,GO:0036094,GO:0042221,GO:0042391,GO:0042493,GO:0042592,GO:0042623,GO:0042626,GO:0042886,GO:0042891,GO:0042908,GO:0042910,GO:0042995,GO:0043167,GO:0043168,GO:0043215,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043269,GO:0043270,GO:0043492,GO:0044057,GO:0044058,GO:0044070,GO:0044093,GO:0044238,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0044770,GO:0044772,GO:0044839,GO:0044840,GO:0044841,GO:0045177,GO:0045332,GO:0045472,GO:0046581,GO:0046618,GO:0046624,GO:0046717,GO:0046903,GO:0046942,GO:0047484,GO:0048058,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050794,GO:0050892,GO:0050896,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051235,GO:0051239,GO:0051384,GO:0051716,GO:0055085,GO:0055088,GO:0060548,GO:0060856,GO:0061024,GO:0061091,GO:0061092,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070161,GO:0070887,GO:0071229,GO:0071310,GO:0071396,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072089,GO:0080090,GO:0080134,GO:0090554,GO:0090555,GO:0097035,GO:0097159,GO:0097367,GO:0097708,GO:0098588,GO:0098590,GO:0098791,GO:0098862,GO:0099038,GO:0099039,GO:0099040,GO:0120025,GO:0120038,GO:1901264,GO:1901265,GO:1901363,GO:1901529,GO:1901557,GO:1901654,GO:1901656,GO:1901700,GO:1901701,GO:1903047,GO:1903412,GO:1903413,GO:1903793,GO:1903959,GO:1903961,GO:1904121,GO:1904478,GO:1905952,GO:1905954,GO:1990962,GO:1990963,GO:2001023,GO:2001025,GO:2001138,GO:2001140,GO:2001225	3.6.3.44	ko:K05658,ko:K05659,ko:K05660	ko02010,ko04976,ko05206,ko05226,map02010,map04976,map05206,map05226	-	-	-	ko00000,ko00001,ko01000,ko02000,ko04090,ko04147	3.A.1.201	-	-	ABC_membrane,ABC_tran
LZS1_k127_5744043_1	404589.Anae109_1713	2.363e-195	632.0	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	cytochrome c	ccsBA	GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
LZS1_k127_5744043_5	290397.Adeh_2104	1.014e-119	395.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
LZS1_k127_5744043_8	1121878.AUGL01000028_gene2068	0.0001623	49.0	2EQBK@1|root,33HXQ@2|Bacteria,1NJKS@1224|Proteobacteria,1SW7A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5744043_7	269799.Gmet_2930	4.635e-11	68.0	COG3005@1|root,COG3005@2|Bacteria,1NJY9@1224|Proteobacteria,42XJ4@68525|delta/epsilon subdivisions,2WSQ4@28221|Deltaproteobacteria,43TRS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	heme-binding sites	cbcC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
LZS1_k127_5744043_4	671143.DAMO_0825	2.392e-131	443.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NNNM@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b subunit of formate dehydrogenase-like protein	mccA	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
LZS1_k127_5744043_3	671143.DAMO_0826	5.157e-141	466.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	ko:K02569,ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrome_C7
LZS1_k127_5744043_0	880073.Calab_1598	0.0	1025.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
LZS1_k127_5744043_2	498848.TaqDRAFT_4327	3.563e-182	581.0	COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10,NmrA
LZS1_k127_5750319_3	742817.HMPREF9449_02626	1.288e-08	66.0	COG3637@1|root,COG3637@2|Bacteria,4PKVN@976|Bacteroidetes,2G057@200643|Bacteroidia,2328H@171551|Porphyromonadaceae	976|Bacteroidetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5750319_0	1123368.AUIS01000005_gene291	2.62e-214	681.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,2NBW5@225057|Acidithiobacillales	225057|Acidithiobacillales	T	GTP-binding protein TypA	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
LZS1_k127_5750319_1	56110.Oscil6304_0453	3.134e-11	76.0	COG0668@1|root,COG0668@2|Bacteria,1G0CX@1117|Cyanobacteria,1H8K1@1150|Oscillatoriales	1117|Cyanobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS1_k127_5750319_2	592028.GCWU000321_00582	8.17e-09	68.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4H5JY@909932|Negativicutes	909932|Negativicutes	M	Transporter, small conductance mechanosensitive ion channel MscS family protein	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
LZS1_k127_5751087_1	314232.SKA53_03071	2.895e-18	91.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,2P8ZF@245186|Loktanella	28211|Alphaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
LZS1_k127_5762855_0	1304880.JAGB01000002_gene1835	8.434e-193	617.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
LZS1_k127_5762855_1	642492.Clole_2579	9.988e-170	548.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia	186801|Clostridia	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS1_k127_5762855_3	335543.Sfum_2381	3.134e-64	236.0	COG4783@1|root,COG4783@2|Bacteria,1R84W@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS1_k127_5762855_7	644282.Deba_3300	3.183e-14	79.0	COG3807@1|root,COG3807@2|Bacteria,1N5AB@1224|Proteobacteria,42URU@68525|delta/epsilon subdivisions,2WQYJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
LZS1_k127_5762855_2	1047013.AQSP01000137_gene516	6.283e-140	469.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
LZS1_k127_5762855_4	401526.TcarDRAFT_0046	1.65e-52	203.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4H20Z@909932|Negativicutes	909932|Negativicutes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
LZS1_k127_5762855_6	876269.ARWA01000001_gene1960	7.509e-28	119.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,3NAHN@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	phoB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_5762855_5	871963.Desdi_1112	3.593e-42	171.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,260UH@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K10681	ko02020,map02020	M00468	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS1_k127_5762855_8	1121918.ARWE01000001_gene1859	0.0002551	49.0	COG0457@1|root,COG0457@2|Bacteria,1NR74@1224|Proteobacteria,42Y51@68525|delta/epsilon subdivisions,2WTS5@28221|Deltaproteobacteria,43U66@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS1_k127_5770856_0	1449049.JONW01000010_gene3524	7.083e-114	381.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
LZS1_k127_5770856_1	1237149.C900_01759	6.853e-106	348.0	COG0621@1|root,COG0621@2|Bacteria,4NEJK@976|Bacteroidetes,47JJ2@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
LZS1_k127_5789667_9	459495.SPLC1_S170330	0.0004132	44.0	COG0463@1|root,COG0463@2|Bacteria,1G153@1117|Cyanobacteria,1H7H6@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS1_k127_5789667_7	204669.Acid345_3927	1.537e-21	108.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
LZS1_k127_5789667_3	398767.Glov_2275	2.753e-66	233.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,43T44@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
LZS1_k127_5789667_1	269799.Gmet_0222	2.427e-126	429.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1MVUS@1224|Proteobacteria,42NB7@68525|delta/epsilon subdivisions,2WNTJ@28221|Deltaproteobacteria,43UJ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
LZS1_k127_5789667_0	1122169.AREN01000013_gene2297	3.594e-196	622.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1JCSD@118969|Legionellales	118969|Legionellales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS1_k127_5789667_6	404589.Anae109_2438	2.053e-24	117.0	COG0642@1|root,COG2205@2|Bacteria,1QVAI@1224|Proteobacteria,43BPQ@68525|delta/epsilon subdivisions,2X70Y@28221|Deltaproteobacteria,2Z3IX@29|Myxococcales	28221|Deltaproteobacteria	F	Protoglobin	-	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0020037,GO:0023014,GO:0023052,GO:0035556,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046906,GO:0046983,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0140096,GO:1901363,GO:1901564	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Protoglobin
LZS1_k127_5789667_2	292459.STH1409	4.14e-95	326.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
LZS1_k127_5789667_4	670487.Ocepr_1217	5.545e-50	189.0	COG0134@1|root,COG0134@2|Bacteria,1WI5W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
LZS1_k127_5789667_5	1111069.TCCBUS3UF1_5490	4.466e-28	121.0	COG0135@1|root,COG0135@2|Bacteria,1WINR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
LZS1_k127_5789667_8	469383.Cwoe_3948	3.022e-17	81.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,4CQPR@84995|Rubrobacteria	84995|Rubrobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS1_k127_5790715_3	646529.Desaci_4601	3.66e-76	264.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,26093@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, C-terminal domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS1_k127_5790715_2	1192034.CAP_6559	2.618e-125	418.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,43A4M@68525|delta/epsilon subdivisions,2WYKE@28221|Deltaproteobacteria,2Z0NN@29|Myxococcales	1224|Proteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
LZS1_k127_5790715_11	7159.AAEL002009-PA	1.155e-11	78.0	KOG3873@1|root,KOG3873@2759|Eukaryota,39U5K@33154|Opisthokonta,3BGK9@33208|Metazoa,3CS5D@33213|Bilateria,41WTA@6656|Arthropoda,3SHMK@50557|Insecta,44ZVZ@7147|Diptera,45FM9@7148|Nematocera	33208|Metazoa	T	Sphingomyelin phosphodiesterase 2	SMPD2	GO:0003674,GO:0003824,GO:0004620,GO:0004767,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005901,GO:0006629,GO:0006643,GO:0006644,GO:0006665,GO:0006672,GO:0006684,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009605,GO:0009612,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010556,GO:0010941,GO:0010942,GO:0016020,GO:0016021,GO:0016298,GO:0016787,GO:0016788,GO:0019216,GO:0019222,GO:0019637,GO:0023052,GO:0030148,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0034248,GO:0034250,GO:0034641,GO:0035556,GO:0042578,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043603,GO:0043604,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044853,GO:0045121,GO:0045834,GO:0046467,GO:0046513,GO:0046889,GO:0046890,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090153,GO:0090154,GO:0097164,GO:0098589,GO:0098590,GO:0098805,GO:0098857,GO:1901564,GO:1901566,GO:1901576,GO:1905038,GO:2000303,GO:2000304	3.1.4.12	ko:K12351	ko00600,ko01100,ko04071,map00600,map01100,map04071	-	R02541	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos
LZS1_k127_5790715_10	498848.TaqDRAFT_3064	2.661e-13	81.0	COG1714@1|root,COG1714@2|Bacteria,1WJWC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
LZS1_k127_5790715_5	1278073.MYSTI_03764	1.462e-52	200.0	COG2114@1|root,COG2114@2|Bacteria,1Q6BC@1224|Proteobacteria,432SK@68525|delta/epsilon subdivisions,2WXUK@28221|Deltaproteobacteria,2YZ4T@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
LZS1_k127_5790715_1	497964.CfE428DRAFT_5205	2.612e-142	470.0	COG1231@1|root,COG1231@2|Bacteria	2|Bacteria	E	oxidoreductase activity	-	-	1.5.99.6	ko:K00316	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R01914,R01915	RC00053,RC00225	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
LZS1_k127_5790715_0	1379270.AUXF01000001_gene2345	1.521e-190	606.0	COG4262@1|root,COG4262@2|Bacteria,1ZU7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
LZS1_k127_5790715_12	420662.Mpe_A0248	7.91e-10	66.0	2EGTE@1|root,33AJI@2|Bacteria,1N5DW@1224|Proteobacteria,2VUCZ@28216|Betaproteobacteria,1KMN4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
LZS1_k127_5790715_14	204669.Acid345_0109	1.587e-07	55.0	291F4@1|root,2ZP1Y@2|Bacteria,3Y93Y@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5790715_4	204669.Acid345_0108	2.256e-63	236.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
LZS1_k127_5790715_15	111780.Sta7437_1224	6.17e-06	59.0	COG3809@1|root,COG3809@2|Bacteria,1G6XN@1117|Cyanobacteria,3VK8D@52604|Pleurocapsales	1117|Cyanobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
LZS1_k127_5790715_8	1192759.AKIB01000003_gene775	7.464e-26	112.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,2U2BP@28211|Alphaproteobacteria,2K3EG@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
LZS1_k127_5790715_7	1304883.KI912532_gene1222	5.719e-41	168.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,2WGZK@28216|Betaproteobacteria,2KW1W@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
LZS1_k127_5790715_6	1254432.SCE1572_49065	2.83e-47	179.0	28M67@1|root,2ZAJW@2|Bacteria,1NV1K@1224|Proteobacteria,4382X@68525|delta/epsilon subdivisions,2X3CZ@28221|Deltaproteobacteria,2YVGS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5801246_6	551789.ATVJ01000001_gene2157	2.017e-23	106.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2U79E@28211|Alphaproteobacteria,43YG9@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Peptidyl-prolyl cis-trans	slyD	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
LZS1_k127_5801246_4	69395.JQLZ01000002_gene1226	2.024e-37	158.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	MA20_41600	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,MASE1,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg,dCache_1
LZS1_k127_5801246_2	1379698.RBG1_1C00001G0613	4.915e-50	184.0	COG1268@1|root,COG1268@2|Bacteria,2NPGG@2323|unclassified Bacteria	2|Bacteria	S	BioY family	bioY	-	-	ko:K02014,ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	1.B.14,2.A.88.1,2.A.88.2	-	-	BioY
LZS1_k127_5801246_0	398767.Glov_1587	4.009e-213	695.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
LZS1_k127_5801246_3	469383.Cwoe_0014	1.095e-49	187.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,4CQ6E@84995|Rubrobacteria	84995|Rubrobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS1_k127_5801246_5	933262.AXAM01000019_gene1136	2.04e-32	137.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,42S8N@68525|delta/epsilon subdivisions,2WNCI@28221|Deltaproteobacteria,2MK0Z@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
LZS1_k127_5801246_1	404589.Anae109_1891	1.675e-69	240.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2YY6V@29|Myxococcales	28221|Deltaproteobacteria	C	Pyruvate flavodoxin ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
LZS1_k127_582185_0	1236689.MMALV_11660	5.467e-60	232.0	COG1348@1|root,COG2710@1|root,arCOG00590@2157|Archaea,arCOG00598@2157|Archaea,2XUKW@28890|Euryarchaeota	28890|Euryarchaeota	D	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_NifH,Oxidored_nitro
LZS1_k127_585353_1	316067.Geob_1241	3.144e-112	383.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
LZS1_k127_585353_5	338966.Ppro_1062	1.949e-43	177.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,43SVG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
LZS1_k127_585353_3	269799.Gmet_0547	1.878e-73	279.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
LZS1_k127_585353_2	1265503.KB905166_gene909	1.006e-88	310.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,2Q5NM@267889|Colwelliaceae	1236|Gammaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_ab
LZS1_k127_585353_7	926554.KI912662_gene1248	3.54e-38	147.0	COG0251@1|root,COG0251@2|Bacteria,1WK0P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS1_k127_585353_0	264462.Bd0608	1.231e-117	406.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,42NS6@68525|delta/epsilon subdivisions,2MST4@213481|Bdellovibrionales,2WKYJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
LZS1_k127_585353_6	861299.J421_1917	3.358e-42	170.0	COG0642@1|root,COG2205@2|Bacteria,1ZTRB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
LZS1_k127_585353_8	292459.STH2398	4.968e-15	88.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
LZS1_k127_585353_4	269799.Gmet_0078	2.615e-68	238.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,42M77@68525|delta/epsilon subdivisions,2WM41@28221|Deltaproteobacteria,43SS1@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS1_k127_5863399_6	56110.Oscil6304_5961	1.207e-40	160.0	COG1028@1|root,COG1028@2|Bacteria	56110.Oscil6304_5961|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5863399_5	56110.Oscil6304_5960	1.127e-45	181.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
LZS1_k127_5863399_2	933262.AXAM01000151_gene828	2.403e-166	540.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
LZS1_k127_5863399_9	562970.Btus_2294	3.843e-12	79.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,4HIUZ@91061|Bacilli,27A2G@186823|Alicyclobacillaceae	91061|Bacilli	O	Hsp20/alpha crystallin family	hsp	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS1_k127_5863399_4	62928.azo3381	8.641e-78	271.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVEE@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
LZS1_k127_5863399_0	56780.SYN_01009	0.0	1055.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MR2C@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
LZS1_k127_5863399_3	153948.NAL212_2689	8.611e-134	434.0	COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,2VIB3@28216|Betaproteobacteria,372IN@32003|Nitrosomonadales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS1_k127_5863399_7	1115512.EH105704_01_05950	2.7e-36	153.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,3XQEW@561|Escherichia	1236|Gammaproteobacteria	S	AI-2E family transporter	VP2476	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS1_k127_5863399_8	1382359.JIAL01000001_gene1287	6.325e-18	85.0	COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
LZS1_k127_5863399_1	118166.JH976537_gene198	2.77e-322	1020.0	COG0841@1|root,COG0841@2|Bacteria,1G21T@1117|Cyanobacteria,1HA63@1150|Oscillatoriales	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS1_k127_586817_2	1487953.JMKF01000009_gene6172	5.283e-30	121.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HCCX@1150|Oscillatoriales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
LZS1_k127_586817_3	314345.SPV1_10991	2.788e-22	100.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria	1224|Proteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
LZS1_k127_586817_1	555079.Toce_0030	4.626e-36	144.0	COG0535@1|root,COG0535@2|Bacteria,1V3MC@1239|Firmicutes,24I1P@186801|Clostridia,42J5X@68295|Thermoanaerobacterales	186801|Clostridia	S	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
LZS1_k127_586817_0	338963.Pcar_1852	1.342e-116	388.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,43SXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
LZS1_k127_587956_0	1177594.MIC448_730006	0.0006071	51.0	COG4221@1|root,COG4221@2|Bacteria,2GN3I@201174|Actinobacteria,4FSGE@85023|Microbacteriaceae	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS1_k127_5922959_6	96561.Dole_0659	1.391e-20	94.0	COG3514@1|root,COG3514@2|Bacteria,1PWSE@1224|Proteobacteria,43A9S@68525|delta/epsilon subdivisions,2WTC0@28221|Deltaproteobacteria,2MP7T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_5922959_4	96561.Dole_0658	7.008e-26	110.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,42VMA@68525|delta/epsilon subdivisions,2WS3K@28221|Deltaproteobacteria,2MKVT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
LZS1_k127_5922959_2	1173029.JH980292_gene2841	2.484e-46	174.0	COG4974@1|root,COG4974@2|Bacteria,1G224@1117|Cyanobacteria,1H8SW@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS1_k127_5922959_3	1123367.C666_17615	6.099e-26	114.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS1_k127_5922959_0	266117.Rxyl_3138	5.341e-125	409.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS1_k127_5922959_1	290397.Adeh_2142	3.421e-57	203.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2WPQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EJ	PFAM Asparaginase	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
LZS1_k127_5922959_5	46234.ANA_C12811	1.763e-22	107.0	COG0860@1|root,COG0860@2|Bacteria,1G008@1117|Cyanobacteria,1HKI1@1161|Nostocales	1117|Cyanobacteria	M	Localisation of periplasmic protein complexes	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
LZS1_k127_5922959_7	1565314.OA34_01615	8.285e-20	93.0	COG2849@1|root,COG2849@2|Bacteria,1MZCG@1224|Proteobacteria,42XCP@68525|delta/epsilon subdivisions,2YQ7V@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
LZS1_k127_5942064_8	69328.PVLB_18085	2.932e-24	116.0	COG2188@1|root,COG2188@2|Bacteria,1QVF7@1224|Proteobacteria,1S5D3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative porin	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Porin_5
LZS1_k127_5942064_1	671143.DAMO_1128	2.279e-80	292.0	COG5002@1|root,COG5002@2|Bacteria,2NNKK@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	phoR	-	2.7.13.3	ko:K02484,ko:K07636,ko:K07768	ko02020,map02020	M00434,M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS1_k127_5942064_3	552811.Dehly_1313	3.639e-63	224.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,34D9D@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_5942064_7	1049564.TevJSym_ad00820	1.341e-25	112.0	COG2062@1|root,COG2062@2|Bacteria,1PKQU@1224|Proteobacteria,1TKA9@1236|Gammaproteobacteria,1J754@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
LZS1_k127_5942064_0	215803.DB30_5662	3.273e-141	480.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
LZS1_k127_5942064_6	317936.Nos7107_0010	1.433e-31	137.0	COG4222@1|root,COG4222@2|Bacteria	2|Bacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Phytase-like,VPEP
LZS1_k127_5942064_5	1144275.COCOR_00243	2.695e-36	147.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2YVU0@29|Myxococcales	28221|Deltaproteobacteria	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos,Metallophos_2
LZS1_k127_5942064_2	313606.M23134_06177	5.005e-72	271.0	COG4320@1|root,COG4320@2|Bacteria,4P18K@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
LZS1_k127_5942064_4	497964.CfE428DRAFT_6354	1.983e-51	207.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
LZS1_k127_5971713_5	927677.ALVU02000001_gene2743	4.785e-26	111.0	COG2259@1|root,COG2259@2|Bacteria,1G88A@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX,SURF4
LZS1_k127_5971713_3	1121866.AUGK01000017_gene1962	1.357e-89	317.0	COG2812@1|root,COG2812@2|Bacteria,2GJKA@201174|Actinobacteria,4CUJ5@84998|Coriobacteriia	84998|Coriobacteriia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
LZS1_k127_5971713_4	1094508.Tsac_0615	9.65e-66	237.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,42F7S@68295|Thermoanaerobacterales	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
LZS1_k127_5971713_1	279714.FuraDRAFT_2563	5.601e-143	486.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1MUBE@1224|Proteobacteria,2VPRG@28216|Betaproteobacteria,2KSUP@206351|Neisseriales	206351|Neisseriales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
LZS1_k127_5971713_7	448385.sce0252	5.508e-05	56.0	COG0457@1|root,COG2956@1|root,COG3118@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3118@2|Bacteria,1MVIW@1224|Proteobacteria,4391J@68525|delta/epsilon subdivisions,2X472@28221|Deltaproteobacteria,2YYDY@29|Myxococcales	28221|Deltaproteobacteria	GO	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_7,TPR_8
LZS1_k127_5971713_2	1242864.D187_006788	2.725e-106	355.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42MHF@68525|delta/epsilon subdivisions,2X5I0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	-	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
LZS1_k127_5971713_0	1144275.COCOR_04760	4.053e-146	475.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42N06@68525|delta/epsilon subdivisions,2X5HZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS1_k127_5971713_6	1457250.BBMO01000001_gene285	7.932e-06	53.0	COG2317@1|root,arCOG04247@2157|Archaea,2XT2Q@28890|Euryarchaeota,23SKK@183963|Halobacteria	183963|Halobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	cxp	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
LZS1_k127_5992105_1	309807.SRU_1904	6.707e-28	128.0	COG3963@1|root,COG3963@2|Bacteria,4NPMV@976|Bacteroidetes,1FK2K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	MTS,Methyltransf_12,Methyltransf_25,RrnaAD
LZS1_k127_5992105_0	404589.Anae109_1500	2.299e-49	184.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS1_k127_6002971_4	545694.TREPR_1033	2.259e-22	98.0	COG0192@1|root,COG0192@2|Bacteria,2J6MD@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
LZS1_k127_6002971_3	631454.N177_1325	2.799e-25	109.0	COG0748@1|root,COG0748@2|Bacteria,1RFVC@1224|Proteobacteria,2TV14@28211|Alphaproteobacteria,1JP1S@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Pyridoxamine 5'-phosphate oxidase	MA20_19930	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx,Pyrid_oxidase_2
LZS1_k127_6002971_1	203119.Cthe_1079	6.126e-91	323.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,3WGIE@541000|Ruminococcaceae	186801|Clostridia	GJM	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I
LZS1_k127_6002971_0	552811.Dehly_1063	1.27e-94	328.0	COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi,34CP8@301297|Dehalococcoidia	301297|Dehalococcoidia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS1_k127_6002971_5	290397.Adeh_1526	4.865e-19	100.0	COG0662@1|root,COG0662@2|Bacteria,1NADF@1224|Proteobacteria,4383M@68525|delta/epsilon subdivisions,2X9WE@28221|Deltaproteobacteria,2YVKF@29|Myxococcales	28221|Deltaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS1_k127_6002971_2	383372.Rcas_3282	1.541e-80	281.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,376T2@32061|Chloroflexia	32061|Chloroflexia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS1_k127_6002971_6	582515.KR51_00001010	8.711e-13	82.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1G0TA@1117|Cyanobacteria	1117|Cyanobacteria	M	COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2,TPR_19
LZS1_k127_6012235_4	1308866.J416_04733	6.704e-06	49.0	COG1826@1|root,COG1826@2|Bacteria,1VGUJ@1239|Firmicutes,4HPB0@91061|Bacilli,4715W@74385|Gracilibacillus	91061|Bacilli	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	-	-	-	-	-	-	-	-	-	MttA_Hcf106
LZS1_k127_6012235_3	673860.AciM339_0317	3.08e-14	79.0	COG0615@1|root,arCOG01222@2157|Archaea,2XX70@28890|Euryarchaeota,3F2RF@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme	ribL	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.7.2	ko:K14656	ko00740,ko01100,ko01110,map00740,map01100,map01110	-	R00161	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
LZS1_k127_6012235_0	261292.Nit79A3_1589	1.604e-50	195.0	COG2211@1|root,COG2211@2|Bacteria,1NR4C@1224|Proteobacteria,2W1HW@28216|Betaproteobacteria	28216|Betaproteobacteria	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS1_k127_6012235_2	755731.Clo1100_3707	5.001e-26	122.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,25AZU@186801|Clostridia,36WDC@31979|Clostridiaceae	186801|Clostridia	M	NlpC/P60 family	spr	-	3.4.17.13	ko:K13694,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
LZS1_k127_6012235_1	1122939.ATUD01000006_gene1643	3.056e-26	125.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPH3@84995|Rubrobacteria	84995|Rubrobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
LZS1_k127_6015086_12	926550.CLDAP_05040	1.788e-20	96.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
LZS1_k127_6015086_1	1192034.CAP_3411	1.563e-211	666.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2YU1A@29|Myxococcales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS1_k127_6015086_6	1232410.KI421422_gene2048	2.661e-58	213.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,43SAN@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	ATP synthase	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
LZS1_k127_6015086_3	579137.Metvu_0072	9.237e-88	299.0	COG0451@1|root,arCOG01369@2157|Archaea,2XTTP@28890|Euryarchaeota,23QE2@183939|Methanococci	183939|Methanococci	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
LZS1_k127_6015086_0	1089553.Tph_c27390	4.535e-217	683.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,42F4E@68295|Thermoanaerobacterales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS1_k127_6015086_9	518766.Rmar_0314	9.719e-29	126.0	COG0712@1|root,COG0712@2|Bacteria,4NSNF@976|Bacteroidetes,1FJFS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
LZS1_k127_6015086_13	646529.Desaci_4629	3.513e-17	88.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,261QU@186807|Peptococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01170	ATP-synt_B
LZS1_k127_6015086_14	1191523.MROS_0275	6.08e-11	67.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
LZS1_k127_6015086_8	1191523.MROS_0276	2.669e-42	165.0	COG0356@1|root,COG0356@2|Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
LZS1_k127_6015086_15	1121957.ATVL01000010_gene422	3.995e-05	50.0	2EFZ5@1|root,339RB@2|Bacteria,4NXH9@976|Bacteroidetes	976|Bacteroidetes	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
LZS1_k127_6015086_4	203119.Cthe_1805	2.904e-87	299.0	COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,3WGN1@541000|Ruminococcaceae	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS1_k127_6015086_5	344747.PM8797T_16917	3.923e-79	282.0	COG0276@1|root,COG0276@2|Bacteria,2IX75@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
LZS1_k127_6015086_2	483219.LILAB_14510	5.222e-143	464.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUBG@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS1_k127_6015086_10	1521187.JPIM01000131_gene1453	8.596e-27	119.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi,377ME@32061|Chloroflexia	32061|Chloroflexia	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
LZS1_k127_6015086_11	1307436.PBF_21068	2.377e-21	97.0	COG5496@1|root,COG5496@2|Bacteria,1UH3T@1239|Firmicutes,4HJC5@91061|Bacilli,1ZI8A@1386|Bacillus	91061|Bacilli	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS1_k127_6027344_1	1173025.GEI7407_2535	3.77e-43	173.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1FZVR@1117|Cyanobacteria,1H8C7@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS1_k127_6027344_0	552811.Dehly_1189	4.84e-53	195.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,34D9D@301297|Dehalococcoidia	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_6027344_2	28072.Nos7524_2070	1.268e-06	55.0	COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria,1HUA6@1161|Nostocales	1117|Cyanobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS1_k127_6027680_20	684949.ATTJ01000002_gene126	2.633e-20	104.0	COG0745@1|root,COG0745@2|Bacteria,1WM5W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K18144	ko01501,map01501	M00649,M00655	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_6027680_13	671143.DAMO_1129	1.937e-53	195.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_6027680_8	903818.KI912268_gene1213	3.885e-78	300.0	COG0457@1|root,COG0726@1|root,COG0457@2|Bacteria,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	icaB	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K21478	-	-	R03096	RC00010	ko00000,ko01000	-	-	-	Polysacc_deac_1
LZS1_k127_6027680_22	903818.KI912268_gene1214	2.352e-11	78.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS1_k127_6027680_7	903818.KI912268_gene1215	7.934e-107	366.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	nodC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006807,GO:0007155,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0019752,GO:0022607,GO:0022610,GO:0030198,GO:0030203,GO:0030212,GO:0030213,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0042710,GO:0043062,GO:0043170,GO:0043436,GO:0044010,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0045226,GO:0046379,GO:0046394,GO:0050501,GO:0051704,GO:0071704,GO:0071840,GO:0071944,GO:0085029,GO:0090605,GO:0090609,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903510	2.4.1.212	ko:K00752,ko:K14666	-	M00664	-	-	ko00000,ko00002,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.4,4.D.1.1.5	GT2	-	Chitin_synth_2,Glyco_tranf_2_3,Glycos_transf_2,PilZ
LZS1_k127_6027680_9	859657.RPSI07_mp0835	3.854e-74	266.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VZW7@28216|Betaproteobacteria,1K2N1@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
LZS1_k127_6027680_19	553207.HMPREF0299_7119	2.115e-22	108.0	COG2120@1|root,COG2120@2|Bacteria,2GMXC@201174|Actinobacteria,22NCW@1653|Corynebacteriaceae	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS1_k127_6027680_12	211165.AJLN01000094_gene1163	7.628e-55	202.0	COG0224@1|root,COG0224@2|Bacteria,1G9F2@1117|Cyanobacteria	1117|Cyanobacteria	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
LZS1_k127_6027680_5	344747.PM8797T_05960	1.079e-161	521.0	COG0677@1|root,COG0677@2|Bacteria,2IXVX@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS1_k127_6027680_3	298653.Franean1_6015	1.453e-184	620.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,4ERD7@85013|Frankiales	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
LZS1_k127_6027680_1	251221.35214134	3.747e-252	819.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_6027680_15	84531.JMTZ01000166_gene1251	1.539e-42	166.0	COG0642@1|root,COG2205@2|Bacteria,1R8JB@1224|Proteobacteria,1TBWY@1236|Gammaproteobacteria,1X9E4@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
LZS1_k127_6027680_16	314230.DSM3645_14835	1.354e-41	162.0	COG2128@1|root,COG2128@2|Bacteria,2IYUM@203682|Planctomycetes	203682|Planctomycetes	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS1_k127_6027680_23	1370121.AUWS01000089_gene4813	8.332e-06	52.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,2335B@1762|Mycobacteriaceae	201174|Actinobacteria	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
LZS1_k127_6027680_10	102129.Lepto7375DRAFT_1998	7.901e-69	254.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HH3F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
LZS1_k127_6027680_17	1173026.Glo7428_2699	2.116e-37	147.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_6027680_14	82654.Pse7367_1662	2.015e-51	205.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1FZVR@1117|Cyanobacteria,1H8C7@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
LZS1_k127_6027680_18	886293.Sinac_3964	5.155e-23	106.0	COG0642@1|root,COG0784@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,2IX8Z@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS_4,Response_reg
LZS1_k127_6027680_11	762376.AXYL_06284	4.291e-64	233.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,3T1CS@506|Alcaligenaceae	1224|Proteobacteria	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
LZS1_k127_6027680_21	383372.Rcas_0491	3.058e-13	82.0	COG0236@1|root,COG0236@2|Bacteria,2G7GE@200795|Chloroflexi	200795|Chloroflexi	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS1_k127_6027680_6	357808.RoseRS_3650	3.992e-110	392.0	COG0171@1|root,COG0171@2|Bacteria,2G7JV@200795|Chloroflexi,375WH@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
LZS1_k127_6027680_2	357808.RoseRS_3649	5.733e-230	754.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi,376WK@32061|Chloroflexia	32061|Chloroflexia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS1_k127_6027680_4	357808.RoseRS_3648	3.482e-177	568.0	COG0318@1|root,COG0318@2|Bacteria,2G5XY@200795|Chloroflexi,37755@32061|Chloroflexia	32061|Chloroflexia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS1_k127_6027680_0	478741.JAFS01000002_gene551	0.0	1044.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46SVA@74201|Verrucomicrobia,37FY0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS1_k127_6040220_3	1121439.dsat_0371	2.394e-15	81.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria,2MCPN@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_6040220_2	395493.BegalDRAFT_3252	9.972e-41	170.0	COG0642@1|root,COG2199@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1RRGT@1236|Gammaproteobacteria,46228@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS1_k127_6040220_0	321327.CYA_2836	4.176e-192	649.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1GYFK@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS1_k127_6040220_1	331678.Cphamn1_2212	1.095e-57	211.0	COG3174@1|root,COG3174@2|Bacteria,1FEIM@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
LZS1_k127_6063646_1	469008.B21_03833	6.13e-33	143.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSI4@1236|Gammaproteobacteria,3XPH1@561|Escherichia	1236|Gammaproteobacteria	T	Member of the two-component regulatory system ZraS ZraR. May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium	zraS	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_2
LZS1_k127_6063646_0	1121335.Clst_2126	2.735e-44	169.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia	186801|Clostridia	T	Response regulator receiver domain protein	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_6063646_2	1318628.MARLIPOL_17278	2.188e-10	67.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,467AA@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG4968 Tfp pilus assembly protein PilE	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
LZS1_k127_6063646_3	1396858.Q666_04690	5.089e-09	63.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria,467AA@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG4968 Tfp pilus assembly protein PilE	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
LZS1_k127_6063646_4	1117315.AHCA01000004_gene806	1.576e-06	51.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria,2Q3CA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	NU	COG4969 Tfp pilus assembly protein, major pilin PilA	ppdD	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650,ko:K02682	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
LZS1_k127_6079113_1	1089551.KE386572_gene2764	1.001e-147	477.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,4BPIN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
LZS1_k127_6079113_0	330214.NIDE1303	1.916e-177	571.0	COG0085@1|root,COG0085@2|Bacteria,3J0CW@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
LZS1_k127_6082992_1	1121335.Clst_0174	1.712e-111	380.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,3WISI@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
LZS1_k127_6082992_0	861299.J421_6048	3.929e-129	423.0	COG0175@1|root,COG0175@2|Bacteria,1ZV0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EH	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
LZS1_k127_6082992_2	1907.SGLAU_31645	2.534e-23	111.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_6086934_1	880073.Calab_1356	2.769e-09	70.0	COG1305@1|root,COG1305@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	TIG,Transglut_core
LZS1_k127_6086934_0	1379698.RBG1_1C00001G1690	5.283e-13	81.0	COG4796@1|root,COG4796@2|Bacteria	2|Bacteria	U	Type ii and iii secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	STN,Secretin,Secretin_N
LZS1_k127_6094108_3	1379698.RBG1_1C00001G0881	2.113e-72	267.0	COG0860@1|root,COG0860@2|Bacteria,2NQ79@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,GHL10,SpoIID
LZS1_k127_6094108_10	316274.Haur_4656	6.78e-18	98.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
LZS1_k127_6094108_8	945713.IALB_2285	6.105e-41	163.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS1_k127_6094108_6	246197.MXAN_2547	2.621e-59	214.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2YUYA@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS1_k127_6094108_5	1266908.AQPB01000029_gene2107	2.974e-61	226.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1X0AW@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
LZS1_k127_6094108_9	404589.Anae109_1700	3.915e-34	148.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS1_k127_6094108_4	1174528.JH992898_gene2626	1.37e-63	225.0	COG0177@1|root,COG0177@2|Bacteria,1G1VI@1117|Cyanobacteria,1JI7U@1189|Stigonemataceae	1117|Cyanobacteria	L	FES	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
LZS1_k127_6094108_1	374847.Kcr_1093	3.194e-146	485.0	COG0747@1|root,arCOG01534@2157|Archaea	2157|Archaea	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_6094108_7	313628.LNTAR_12581	1.576e-48	182.0	2CAZH@1|root,2Z7RU@2|Bacteria	2|Bacteria	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
LZS1_k127_6094108_0	324602.Caur_1881	1.287e-313	982.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS1_k127_6094108_2	1270196.JCKI01000008_gene1416	1.815e-109	359.0	COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,1IQMQ@117747|Sphingobacteriia	976|Bacteroidetes	C	Succinate dehydrogenase fumarate reductase Fe-S protein subunit	frdB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
LZS1_k127_6094108_11	55529.EKX33906	1.035e-17	93.0	COG0216@1|root,KOG2726@2759|Eukaryota	2759|Eukaryota	J	translation release factor activity	C12orf65	GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0015934,GO:0016020,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0019866,GO:0022411,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032268,GO:0032543,GO:0032984,GO:0032991,GO:0034248,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0070013,GO:0070126,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0098798,GO:0140053,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112	2.1.1.43,2.4.2.12	ko:K03462,ko:K11428	ko00310,ko00760,ko01100,ko04621,map00310,map00760,map01100,map04621	-	R01271,R03875,R03938,R04866,R04867	RC00003,RC00033,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko03036	-	-	-	RF-1
LZS1_k127_6094108_12	300852.55771608	5.612e-17	93.0	COG4911@1|root,COG4911@2|Bacteria,1WJWB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
LZS1_k127_6114484_4	96561.Dole_2899	2.938e-68	259.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
LZS1_k127_6114484_1	1297742.A176_02788	1.113e-139	449.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2WJAI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS1_k127_6114484_2	204669.Acid345_4707	6.812e-127	439.0	COG2225@1|root,COG2225@2|Bacteria,3Y4MK@57723|Acidobacteria,2JKQY@204432|Acidobacteriia	204432|Acidobacteriia	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
LZS1_k127_6114484_9	883.DvMF_0691	2.612e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42P80@68525|delta/epsilon subdivisions,2WMCB@28221|Deltaproteobacteria,2MG6A@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM PEP-CTERM system TPR-repeat lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS1_k127_6114484_5	1232410.KI421413_gene827	6.272e-48	192.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43S50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
LZS1_k127_6114484_6	1007104.SUS17_1879	1.269e-10	74.0	COG0454@1|root,COG0456@2|Bacteria,1N4JC@1224|Proteobacteria,2UCY3@28211|Alphaproteobacteria,2K4ZS@204457|Sphingomonadales	204457|Sphingomonadales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
LZS1_k127_6114484_0	395961.Cyan7425_1966	1.113e-164	532.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3KGCF@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00128,ko:K00130,ko:K00135,ko:K00138,ko:K00146	ko00010,ko00053,ko00071,ko00250,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135,M00555	R00264,R00631,R00710,R00711,R00713,R00714,R00904,R01752,R01986,R02401,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS1_k127_6114484_3	1111479.AXAR01000006_gene806	2.258e-89	306.0	COG1028@1|root,COG1028@2|Bacteria,1TSWA@1239|Firmicutes,4HBHR@91061|Bacilli	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS1_k127_6114484_8	1192034.CAP_5961	8.7e-08	64.0	COG0560@1|root,COG0560@2|Bacteria,1R4DN@1224|Proteobacteria,43240@68525|delta/epsilon subdivisions,2WXVH@28221|Deltaproteobacteria,2YYEZ@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
LZS1_k127_6114484_7	1123267.JONN01000001_gene1095	2.131e-09	61.0	COG1899@1|root,COG1899@2|Bacteria,1MVC6@1224|Proteobacteria,2TTRW@28211|Alphaproteobacteria,2K1R2@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
LZS1_k127_6168819_1	3067.XP_002953587.1	5.403e-05	47.0	COG1612@1|root,KOG2725@2759|Eukaryota,37NYZ@33090|Viridiplantae,34J3G@3041|Chlorophyta	3041|Chlorophyta	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
LZS1_k127_6168819_0	292459.STH2398	4.447e-49	197.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1VRP7@1239|Firmicutes,24YHW@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_9,Response_reg
LZS1_k127_6174780_7	221359.RS9916_36967	3.955e-19	100.0	COG0500@1|root,COG2226@2|Bacteria,1G49I@1117|Cyanobacteria,1GZF6@1129|Synechococcus	1117|Cyanobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
LZS1_k127_6174780_5	1210884.HG799468_gene13815	2.035e-25	119.0	COG1959@1|root,COG1959@2|Bacteria,2J1K3@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS1_k127_6174780_3	102125.Xen7305DRAFT_00030290	9.903e-66	231.0	COG0778@1|root,COG0778@2|Bacteria,1G2KA@1117|Cyanobacteria,3VIH1@52604|Pleurocapsales	1117|Cyanobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS1_k127_6174780_2	8932.XP_005499007.1	1.048e-92	316.0	COG0604@1|root,KOG1198@2759|Eukaryota,39JG1@33154|Opisthokonta,3BDWX@33208|Metazoa,3CW7R@33213|Bilateria,485F7@7711|Chordata,48ZFQ@7742|Vertebrata,4GMQ3@8782|Aves	33208|Metazoa	C	Quinone oxidoreductase	CRYZ	GO:0000166,GO:0003008,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003960,GO:0005198,GO:0005212,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006805,GO:0007600,GO:0007601,GO:0008150,GO:0008152,GO:0009056,GO:0009410,GO:0009987,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0022607,GO:0032501,GO:0036094,GO:0042178,GO:0042221,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0050877,GO:0050896,GO:0050953,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070402,GO:0070887,GO:0071466,GO:0071840,GO:0097159,GO:1901265,GO:1901363	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS1_k127_6174780_0	1144275.COCOR_06855	5.648e-115	382.0	COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,43B2H@68525|delta/epsilon subdivisions,2X6GI@28221|Deltaproteobacteria,2YUTY@29|Myxococcales	28221|Deltaproteobacteria	I	Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
LZS1_k127_6174780_4	246197.MXAN_6842	7.328e-41	158.0	COG0664@1|root,COG0664@2|Bacteria,1N8JB@1224|Proteobacteria,42XHI@68525|delta/epsilon subdivisions,2WT5U@28221|Deltaproteobacteria,2Z2TU@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
LZS1_k127_6174780_1	1007103.AFHW01000160_gene3089	7.825e-100	337.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
LZS1_k127_6174780_6	760117.JN27_07375	3.456e-23	107.0	292BS@1|root,2ZPW7@2|Bacteria,1REGA@1224|Proteobacteria,2VTQU@28216|Betaproteobacteria,474IK@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6174780_8	1267535.KB906767_gene3246	4.933e-06	49.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
LZS1_k127_6182926_2	264462.Bd2627	9.209e-48	179.0	COG3591@1|root,COG3591@2|Bacteria,1NP6U@1224|Proteobacteria,42ZKY@68525|delta/epsilon subdivisions,2MTXG@213481|Bdellovibrionales,2WUS6@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
LZS1_k127_6182926_0	1282362.AEAC466_03885	6.083e-99	359.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS1_k127_6182926_1	686340.Metal_1980	1.931e-73	261.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria,1RXGJ@1236|Gammaproteobacteria,1XG8M@135618|Methylococcales	135618|Methylococcales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
LZS1_k127_6204005_0	404380.Gbem_1114	3.165e-25	120.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
LZS1_k127_622712_6	1191523.MROS_1616	9.487e-17	93.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_1616|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_622712_3	941639.BCO26_1556	9.827e-32	129.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,1ZFJ7@1386|Bacillus	91061|Bacilli	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
LZS1_k127_622712_8	1244869.H261_09053	6.599e-13	79.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2UAKC@28211|Alphaproteobacteria,2JSGU@204441|Rhodospirillales	204441|Rhodospirillales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
LZS1_k127_622712_2	1123250.KB908394_gene1896	2.208e-65	235.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,4H28B@909932|Negativicutes	909932|Negativicutes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
LZS1_k127_622712_1	1128421.JAGA01000002_gene62	3.488e-87	306.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
LZS1_k127_622712_0	1502850.FG91_03173	1.773e-126	414.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2TSBX@28211|Alphaproteobacteria,2K1AI@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.2	ko:K21053	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
LZS1_k127_622712_4	261292.Nit79A3_1337	1.539e-30	132.0	COG2267@1|root,COG2267@2|Bacteria,1PE8E@1224|Proteobacteria,2W9K3@28216|Betaproteobacteria,373RZ@32003|Nitrosomonadales	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS1_k127_622712_9	796620.VIBC2010_05104	3.384e-12	76.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1XXTP@135623|Vibrionales	135623|Vibrionales	J	COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
LZS1_k127_622712_7	465541.ATCJ01000005_gene1128	6.162e-15	81.0	COG0745@1|root,COG0745@2|Bacteria,2GMZ7@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_622712_5	880073.Calab_2217	3.507e-18	95.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
LZS1_k127_622712_10	768704.Desmer_0594	5.263e-07	59.0	COG2247@1|root,COG2247@2|Bacteria,1UN1B@1239|Firmicutes,25GU9@186801|Clostridia,263E6@186807|Peptococcaceae	186801|Clostridia	M	cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,DUF4430
LZS1_k127_6228386_2	1499967.BAYZ01000147_gene695	2.455e-55	210.0	COG0472@1|root,COG0472@2|Bacteria	2|Bacteria	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
LZS1_k127_6228386_7	1499967.BAYZ01000158_gene458	4.054e-23	116.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
LZS1_k127_6228386_0	344747.PM8797T_24426	3.53e-97	323.0	COG1216@1|root,COG1216@2|Bacteria,2IYBZ@203682|Planctomycetes	203682|Planctomycetes	S	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_6228386_5	156889.Mmc1_0977	1.123e-34	145.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase	MA20_24380	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
LZS1_k127_6228386_13	1385518.N798_14520	8.278e-11	70.0	COG2227@1|root,COG2227@2|Bacteria,2GMMX@201174|Actinobacteria,4FIJN@85021|Intrasporangiaceae	201174|Actinobacteria	H	Methionine biosynthesis protein MetW	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
LZS1_k127_6228386_8	469383.Cwoe_3709	1.154e-21	110.0	COG1807@1|root,COG1807@2|Bacteria,2HNIC@201174|Actinobacteria,4CPHR@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_6228386_12	929558.SMGD1_0474	1.959e-12	79.0	COG1807@1|root,COG1807@2|Bacteria,1RM6R@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_6228386_1	504472.Slin_2870	5.247e-73	252.0	COG1215@1|root,COG1215@2|Bacteria,4NF0S@976|Bacteroidetes,47UDR@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_6228386_4	1184267.A11Q_1747	6.41e-38	147.0	COG1393@1|root,COG1393@2|Bacteria,1Q3YZ@1224|Proteobacteria,42XF4@68525|delta/epsilon subdivisions,2WSMU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
LZS1_k127_6228386_3	365046.Rta_28800	1.204e-38	167.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,4A9SZ@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS1_k127_6228386_10	83406.HDN1F_20900	2.422e-20	96.0	2F6ZB@1|root,33ZF9@2|Bacteria,1NYFX@1224|Proteobacteria,1SQCF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4279
LZS1_k127_6228386_14	1122997.AUDD01000014_gene1487	0.0005155	46.0	2CBZI@1|root,339ZR@2|Bacteria,2H81E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6228386_11	5911.EAR82404	3.048e-13	77.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS1_k127_6228386_6	394221.Mmar10_0837	9.122e-32	126.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,2UCR7@28211|Alphaproteobacteria,43YBS@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS1_k127_6228386_9	357804.Ping_2525	1.763e-21	100.0	2DZEP@1|root,32V8S@2|Bacteria,1NZB5@1224|Proteobacteria,1SQY7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_622936_4	1380394.JADL01000009_gene3147	1.233e-17	94.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
LZS1_k127_622936_3	1121940.AUDZ01000006_gene199	3.219e-22	102.0	COG0745@1|root,COG0745@2|Bacteria,1RA6Z@1224|Proteobacteria,1SYDG@1236|Gammaproteobacteria,1XP8J@135619|Oceanospirillales	135619|Oceanospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ygiX	-	-	ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_622936_1	997346.HMPREF9374_2019	8.926e-78	281.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,27AWY@186824|Thermoactinomycetaceae	91061|Bacilli	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
LZS1_k127_622936_2	760568.Desku_0372	4.261e-49	187.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
LZS1_k127_622936_5	102125.Xen7305DRAFT_00028860	2.882e-14	87.0	COG0438@1|root,COG0457@1|root,COG1216@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG1216@2|Bacteria,1G2HS@1117|Cyanobacteria,3VKW9@52604|Pleurocapsales	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_622936_0	1121438.JNJA01000002_gene3616	2.948e-135	444.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2M8HY@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS1_k127_6248823_1	266117.Rxyl_0486	9.772e-64	233.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GMFH@201174|Actinobacteria,4CPMF@84995|Rubrobacteria	84995|Rubrobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
LZS1_k127_6248823_4	1121033.AUCF01000005_gene5307	2.869e-12	72.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2UD5T@28211|Alphaproteobacteria,2JX90@204441|Rhodospirillales	204441|Rhodospirillales	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6248823_3	1231391.AMZF01000017_gene180	5.655e-21	100.0	29FE7@1|root,302BX@2|Bacteria,1NXED@1224|Proteobacteria,2W8VK@28216|Betaproteobacteria,3T7DI@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6248823_2	309801.trd_1713	4.554e-59	221.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27XEZ@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS1_k127_6248823_0	1267535.KB906767_gene99	1.27e-302	942.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria,2JIAE@204432|Acidobacteriia	204432|Acidobacteriia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS1_k127_6256313_1	1286171.EAL2_808p03370	2.647e-61	228.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,25ZF5@186806|Eubacteriaceae	186801|Clostridia	O	Subtilase family	isp	-	3.4.21.62	ko:K01342,ko:K13275	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
LZS1_k127_6256313_4	1504822.CCNO01000014_gene1643	0.0001036	56.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
LZS1_k127_6256313_2	269799.Gmet_3232	3.655e-34	142.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43TXA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
LZS1_k127_6256313_0	867903.ThesuDRAFT_01613	3.115e-68	255.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS1_k127_6256313_3	1237149.C900_05483	1.223e-12	80.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
LZS1_k127_6260704_0	204669.Acid345_3520	2.482e-295	919.0	COG0365@1|root,COG0365@2|Bacteria,3Y39K@57723|Acidobacteria,2JI3Z@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS1_k127_6260704_5	1118054.CAGW01000024_gene358	2.72e-06	60.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,4HHPX@91061|Bacilli	91061|Bacilli	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS1_k127_6260704_7	290512.Paes_0194	0.0002596	52.0	COG1381@1|root,COG1381@2|Bacteria,1FE9W@1090|Chlorobi	1090|Chlorobi	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
LZS1_k127_6260704_3	269799.Gmet_2942	1.368e-115	381.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria,43UE2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
LZS1_k127_6260704_2	1121472.AQWN01000010_gene562	5.906e-124	422.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,2608I@186807|Peptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
LZS1_k127_6260704_6	304371.MCP_1390	1.218e-05	54.0	arCOG13226@1|root,arCOG13226@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6260704_4	1121013.P873_14190	2.317e-97	325.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,1X5FC@135614|Xanthomonadales	135614|Xanthomonadales	S	Extradiol ring-cleavage dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
LZS1_k127_6260704_1	240016.ABIZ01000001_gene2673	3.54e-151	497.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
LZS1_k127_6326219_3	1499967.BAYZ01000009_gene5396	4.03e-36	139.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS1_k127_6326219_0	748727.CLJU_c37190	1.762e-211	669.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,36E1F@31979|Clostridiaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS1_k127_6326219_4	227377.CBU_0943	6.464e-19	92.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese,SNARE_assoc
LZS1_k127_6326219_5	243160.BMAA0382	1.722e-18	90.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2VI9S@28216|Betaproteobacteria,1K7KF@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
LZS1_k127_6326219_2	648996.Theam_1066	4.03e-45	171.0	COG0325@1|root,COG0325@2|Bacteria,2G3XD@200783|Aquificae	200783|Aquificae	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
LZS1_k127_6326219_6	497964.CfE428DRAFT_3040	5.638e-11	73.0	COG1872@1|root,COG1872@2|Bacteria,46T9T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
LZS1_k127_6326219_1	1121428.DESHY_40040___1	9.546e-95	323.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,260GP@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
LZS1_k127_6364969_1	396588.Tgr7_1409	2.014e-61	223.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales	135613|Chromatiales	L	Helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
LZS1_k127_6364969_2	502025.Hoch_5233	2.22e-23	105.0	COG4323@1|root,COG4323@2|Bacteria,1N16T@1224|Proteobacteria,4315K@68525|delta/epsilon subdivisions,2WWYY@28221|Deltaproteobacteria,2YVYB@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
LZS1_k127_6364969_0	1242864.D187_005156	3.098e-176	576.0	COG0467@1|root,COG0467@2|Bacteria,1NM7E@1224|Proteobacteria,42SM2@68525|delta/epsilon subdivisions,2WPEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
LZS1_k127_6371231_5	1125863.JAFN01000001_gene2290	5.233e-32	130.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
LZS1_k127_6371231_6	757424.Hsero_4670	1.99e-27	116.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,474NW@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
LZS1_k127_6371231_4	1121920.AUAU01000023_gene2421	2.034e-65	238.0	COG0805@1|root,COG0805@2|Bacteria,3Y57K@57723|Acidobacteria	57723|Acidobacteria	U	Sec-independent protein translocase protein (TatC)	-	-	-	-	-	-	-	-	-	-	-	-	TatC
LZS1_k127_6371231_13	365046.Rta_29270	1.79e-05	53.0	COG3620@1|root,COG3620@2|Bacteria,1N9I8@1224|Proteobacteria,2VWM7@28216|Betaproteobacteria,4AFJH@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, XRE family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
LZS1_k127_6371231_9	1235802.C823_02056	1.166e-13	85.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,25UUT@186806|Eubacteriaceae	186801|Clostridia	F	Phosphoribulokinase uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
LZS1_k127_6371231_7	648996.Theam_0278	2.027e-25	124.0	COG0563@1|root,COG0563@2|Bacteria,2G42Z@200783|Aquificae	200783|Aquificae	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
LZS1_k127_6371231_3	383372.Rcas_4255	8.377e-152	492.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
LZS1_k127_6371231_0	439235.Dalk_0610	8.627e-209	664.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2MHYG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM malic	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
LZS1_k127_6371231_1	1111069.TCCBUS3UF1_16380	1.842e-182	582.0	COG0473@1|root,COG0473@2|Bacteria,1WIRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS1_k127_6371231_2	1173027.Mic7113_3322	5.008e-158	508.0	COG0477@1|root,COG2814@2|Bacteria,1G1K4@1117|Cyanobacteria,1H9RK@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major facilitator superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
LZS1_k127_6371231_8	880073.Calab_2217	2.719e-22	108.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
LZS1_k127_6371231_11	264732.Moth_1459	1.236e-08	70.0	COG1657@1|root,COG5492@1|root,COG1657@2|Bacteria,COG5492@2|Bacteria,1UY4I@1239|Firmicutes,24E8I@186801|Clostridia,42EWE@68295|Thermoanaerobacterales	186801|Clostridia	I	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430,Prenyltrans,SLH
LZS1_k127_6371231_12	251221.35212356	1.627e-08	70.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	ASH,Cadherin-like,DUF1573,TIG,VWA
LZS1_k127_6371231_10	573061.Clocel_1183	1.091e-12	83.0	COG4733@1|root,COG4733@2|Bacteria,1UEBB@1239|Firmicutes,24DIX@186801|Clostridia,36HNU@31979|Clostridiaceae	186801|Clostridia	N	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6380900_0	290397.Adeh_0012	8.425e-256	822.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
LZS1_k127_6380900_6	880073.Calab_0980	1.56e-23	108.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS1_k127_6380900_5	293826.Amet_2457	3.712e-25	118.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,36EAC@31979|Clostridiaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS1_k127_6380900_2	1415779.JOMH01000001_gene2948	4.332e-37	158.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S6X1@1236|Gammaproteobacteria,1X450@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
LZS1_k127_6380900_7	1267533.KB906733_gene3589	6.314e-22	106.0	COG0824@1|root,COG0824@2|Bacteria,3Y4WZ@57723|Acidobacteria,2JJIE@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
LZS1_k127_6380900_9	56110.Oscil6304_4074	2.874e-15	86.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1GHCI@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF,GGDEF,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
LZS1_k127_6380900_4	243231.GSU0360	6.251e-30	127.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R4WG@1224|Proteobacteria,43AIM@68525|delta/epsilon subdivisions,2X5YU@28221|Deltaproteobacteria,43SWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
LZS1_k127_6380900_1	1121405.dsmv_3194	1.315e-42	160.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
LZS1_k127_6380900_8	1150626.PHAMO_10284	1.94e-15	88.0	COG1215@1|root,COG1215@2|Bacteria,1Q6U2@1224|Proteobacteria,2VG3U@28211|Alphaproteobacteria,2JRWC@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family group 2	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
LZS1_k127_6380900_3	227377.CBU_0037	2.281e-31	130.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b0954,iB21_1397.B21_00965,iBWG_1329.BWG_0806,iE2348C_1286.E2348C_0940,iEC042_1314.EC042_1039,iECBD_1354.ECBD_2641,iECB_1328.ECB_00958,iECDH10B_1368.ECDH10B_1024,iECD_1391.ECD_00958,iECED1_1282.ECED1_0977,iECH74115_1262.ECH74115_1118,iECIAI1_1343.ECIAI1_0995,iECIAI39_1322.ECIAI39_2193,iECNA114_1301.ECNA114_1032,iECO103_1326.ECO103_1000,iECO111_1330.ECO111_1022,iECO26_1355.ECO26_1081,iECOK1_1307.ECOK1_1013,iECS88_1305.ECS88_0975,iECSF_1327.ECSF_0868,iECSP_1301.ECSP_1060,iECUMN_1333.ECUMN_1143,iECW_1372.ECW_m1064,iECs_1301.ECs1038,iEKO11_1354.EKO11_2876,iETEC_1333.ETEC_1024,iEcE24377_1341.EcE24377A_1068,iEcHS_1320.EcHS_A1063,iEcSMS35_1347.EcSMS35_2166,iEcolC_1368.EcolC_2642,iG2583_1286.G2583_1189,iJO1366.b0954,iJR904.b0954,iLF82_1304.LF82_0604,iSBO_1134.SBO_2277,iSDY_1059.SDY_0927,iSF_1195.SF0954,iSSON_1240.SSON_0958,iSbBS512_1146.SbBS512_E2362,iUMNK88_1353.UMNK88_1108,iWFL_1372.ECW_m1064,iY75_1357.Y75_RS04955,iZ_1308.Z1304,ic_1306.c1090	FabA
LZS1_k127_6389039_1	518766.Rmar_0066	2.18e-11	76.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,1FJ0W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
LZS1_k127_6389039_0	391008.Smal_2281	6.358e-13	79.0	COG4232@1|root,COG4232@2|Bacteria,1QWZ3@1224|Proteobacteria,1T30Q@1236|Gammaproteobacteria,1XD9K@135614|Xanthomonadales	135614|Xanthomonadales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
LZS1_k127_6407219_6	1120936.KB907213_gene4912	5.309e-23	104.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4EHAF@85012|Streptosporangiales	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
LZS1_k127_6407219_7	1051632.TPY_0861	1.929e-16	93.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,3WDH5@538999|Clostridiales incertae sedis	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
LZS1_k127_6407219_0	1192034.CAP_0604	2.097e-127	428.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YU4Q@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
LZS1_k127_6407219_5	1131269.AQVV01000018_gene1932	1.083e-25	118.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
LZS1_k127_6407219_3	404589.Anae109_1291	1.363e-66	236.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WN9U@28221|Deltaproteobacteria,2YUX6@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3354	Oxidored_q6
LZS1_k127_6407219_8	221359.RS9916_38851	1.997e-15	82.0	COG0838@1|root,COG0838@2|Bacteria,1G5RH@1117|Cyanobacteria,1H0GX@1129|Synechococcus	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhC	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K05574	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q4
LZS1_k127_6407219_4	903818.KI912268_gene3224	7.116e-44	180.0	COG1007@1|root,COG1007@2|Bacteria,3Y43Y@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS1_k127_6407219_2	237368.SCABRO_01998	1.736e-107	386.0	COG1008@1|root,COG1008@2|Bacteria,2IX79@203682|Planctomycetes	203682|Planctomycetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
LZS1_k127_6407219_1	264732.Moth_0985	1.486e-107	376.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,24A16@186801|Clostridia,42FX8@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	ndhF	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
LZS1_k127_6407219_11	1089455.MOPEL_031_00330	0.0001518	52.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4F74V@85018|Dermatophilaceae	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
LZS1_k127_6407219_10	565045.NOR51B_944	1.418e-06	56.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria,1J6P9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2280,iAF1260.b2280,iAPECO1_1312.APECO1_4285,iB21_1397.B21_02165,iBWG_1329.BWG_2054,iE2348C_1286.E2348C_2420,iEC042_1314.EC042_2521,iEC55989_1330.EC55989_2524,iECABU_c1320.ECABU_c26120,iECBD_1354.ECBD_1381,iECB_1328.ECB_02205,iECDH10B_1368.ECDH10B_2442,iECDH1ME8569_1439.ECDH1ME8569_2217,iECD_1391.ECD_02205,iECED1_1282.ECED1_2744,iECH74115_1262.ECH74115_3419,iECIAI1_1343.ECIAI1_2354,iECIAI39_1322.ECIAI39_2427,iECNA114_1301.ECNA114_2370,iECO103_1326.ECO103_2744,iECO111_1330.ECO111_3028,iECO26_1355.ECO26_3268,iECOK1_1307.ECOK1_2513,iECP_1309.ECP_2319,iECS88_1305.ECS88_2427,iECSE_1348.ECSE_2537,iECSF_1327.ECSF_2157,iECSP_1301.ECSP_3154,iECUMN_1333.ECUMN_2619,iECW_1372.ECW_m2468,iECs_1301.ECs3164,iEKO11_1354.EKO11_1487,iETEC_1333.ETEC_2415,iEcDH1_1363.EcDH1_1377,iEcE24377_1341.EcE24377A_2573,iEcHS_1320.EcHS_A2429,iEcSMS35_1347.EcSMS35_2434,iEcolC_1368.EcolC_1372,iJO1366.b2280,iJR904.b2280,iLF82_1304.LF82_1547,iNRG857_1313.NRG857_11545,iSBO_1134.SBO_2313,iSDY_1059.SDY_2476,iSFV_1184.SFV_2347,iSF_1195.SF2356,iSFxv_1172.SFxv_2600,iSSON_1240.SSON_2337,iS_1188.S2491,iSbBS512_1146.SbBS512_E2656,iUMN146_1321.UM146_05415,iUMNK88_1353.UMNK88_2830,iUTI89_1310.UTI89_C2560,iWFL_1372.ECW_m2468,iY75_1357.Y75_RS11955,iZ_1308.Z3539,ic_1306.c2821	Oxidored_q3
LZS1_k127_6407219_9	561175.KB894094_gene1749	4.277e-09	68.0	COG0392@1|root,COG0392@2|Bacteria,2I1QT@201174|Actinobacteria,4EPCF@85012|Streptosporangiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
LZS1_k127_6419615_2	374847.Kcr_1093	1.728e-47	178.0	COG0747@1|root,arCOG01534@2157|Archaea	2157|Archaea	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_6419615_0	374847.Kcr_1093	1.895e-144	481.0	COG0747@1|root,arCOG01534@2157|Archaea	2157|Archaea	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_6419615_1	1499967.BAYZ01000065_gene6083	2.195e-63	225.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_6492424_1	591158.SSMG_05700	4.726e-113	374.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB2	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS1_k127_6492424_0	404589.Anae109_1713	3.507e-196	631.0	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	cytochrome c	ccsBA	GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
LZS1_k127_6492424_2	1121920.AUAU01000001_gene2236	4.941e-20	90.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm,ResB
LZS1_k127_651405_0	888060.HMPREF9081_0862	3.652e-108	363.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H2HH@909932|Negativicutes	909932|Negativicutes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS1_k127_651405_5	1541065.JRFE01000012_gene2427	5.849e-37	152.0	COG1215@1|root,COG1215@2|Bacteria,1G46A@1117|Cyanobacteria,3VIYH@52604|Pleurocapsales	1117|Cyanobacteria	M	COGs COG0463 Glycosyltransferase involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_651405_6	926566.Terro_1883	6.578e-27	124.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83,6.2.1.30	ko:K00721,ko:K01912,ko:K08301	ko00360,ko00510,ko01100,ko01120,ko05111,map00360,map00510,map01100,map01120,map05111	-	R01009,R02539	RC00004,RC00005,RC00014	ko00000,ko00001,ko01000,ko01003,ko03009,ko03019	-	GT2	-	Glycos_transf_2
LZS1_k127_651405_4	118173.KB235914_gene997	5.055e-39	165.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528,ko:K20444	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko01005,ko02000,ko03009	4.D.1.3	GT2,GT4	-	CTP_transf_like,Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_12,Methyltransf_23,RrnaAD
LZS1_k127_651405_1	886293.Sinac_3912	1.246e-74	267.0	COG0463@1|root,COG0463@2|Bacteria,2IZV0@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_651405_2	521011.Mpal_2127	1.056e-67	252.0	COG0451@1|root,arCOG04627@2157|Archaea,2XW3U@28890|Euryarchaeota,2NABN@224756|Methanomicrobia	224756|Methanomicrobia	M	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
LZS1_k127_651405_3	1353529.M899_1416	2.388e-55	211.0	COG0463@1|root,COG0463@2|Bacteria,1Q5I6@1224|Proteobacteria,431AR@68525|delta/epsilon subdivisions,2WW8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_651405_7	1499689.CCNN01000007_gene1497	3.881e-10	74.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia,36ERI@31979|Clostridiaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
LZS1_k127_6517366_0	1183438.GKIL_3659	1.533e-51	197.0	COG0683@1|root,COG0683@2|Bacteria,1G16P@1117|Cyanobacteria	1117|Cyanobacteria	E	'ABC-type branched-chain amino acid transport	natB	-	-	ko:K01999,ko:K11954	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	ANF_receptor,Peripla_BP_6
LZS1_k127_6517366_1	1254432.SCE1572_32735	1.055e-40	162.0	COG3239@1|root,COG3239@2|Bacteria,1PG0I@1224|Proteobacteria,435AQ@68525|delta/epsilon subdivisions,2WZMU@28221|Deltaproteobacteria,2Z2E6@29|Myxococcales	28221|Deltaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
LZS1_k127_6517366_2	314278.NB231_14198	5.804e-35	153.0	COG0491@1|root,COG0491@2|Bacteria,1RGCD@1224|Proteobacteria,1S4WB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
LZS1_k127_6517366_3	883096.HMPREF9699_01029	3.408e-12	72.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1I3JR@117743|Flavobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS1_k127_6522272_1	192875.XP_004342595.1	0.0002899	53.0	KOG1225@1|root,KOG1225@2759|Eukaryota	2759|Eukaryota	L	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	-	-	-	ko:K01691	ko04310,map04310	-	-	-	ko00000,ko00001	-	-	-	EGF_2,WIF
LZS1_k127_6522272_0	518766.Rmar_2817	5.288e-21	104.0	COG2067@1|root,COG2067@2|Bacteria,4NWE8@976|Bacteroidetes	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
LZS1_k127_6528599_2	1214101.BN159_5030	0.0002029	53.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
LZS1_k127_6528599_0	517417.Cpar_0119	2.625e-07	63.0	COG2710@1|root,COG2710@2|Bacteria,1FDAE@1090|Chlorobi	1090|Chlorobi	C	TIGRFAM chlorophyllide reductase subunit Z	-	-	1.3.7.14,1.3.7.15	ko:K11335	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro,PCP_red
LZS1_k127_6528599_1	481448.Minf_1872	1.46e-06	60.0	COG2710@1|root,COG2710@2|Bacteria,46TQA@74201|Verrucomicrobia,37FYD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
LZS1_k127_6562898_4	398578.Daci_4622	6.457e-08	62.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria,4AD9Q@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM TonB family protein	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS1_k127_6562898_5	1123274.KB899421_gene1813	3.871e-07	61.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
LZS1_k127_6562898_0	351627.Csac_1955	6.802e-303	956.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,42F5B@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS1_k127_6562898_1	401526.TcarDRAFT_0689	1.057e-136	442.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H298@909932|Negativicutes	909932|Negativicutes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
LZS1_k127_6562898_3	1267533.KB906734_gene4271	6.038e-93	314.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
LZS1_k127_6562898_2	273068.TTE1761	1.156e-124	439.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,42F8F@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
LZS1_k127_6562898_6	717231.Flexsi_1772	0.00025	45.0	COG1314@1|root,COG1314@2|Bacteria,2GG1M@200930|Deferribacteres	200930|Deferribacteres	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
LZS1_k127_6582974_3	1201288.M900_1599	8.82e-33	134.0	COG1595@1|root,COG1595@2|Bacteria,1RI7C@1224|Proteobacteria,42XJU@68525|delta/epsilon subdivisions,2WT13@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS1_k127_6582974_1	452637.Oter_0307	2.925e-64	229.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
LZS1_k127_6582974_2	1125863.JAFN01000001_gene3578	1.135e-61	218.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,42R7A@68525|delta/epsilon subdivisions,2WN7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS1_k127_6582974_0	756067.MicvaDRAFT_1313	9.226e-201	636.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria,1H7PH@1150|Oscillatoriales	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
LZS1_k127_6582974_4	1392501.JIAC01000001_gene283	1.389e-10	73.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,4H27F@909932|Negativicutes	909932|Negativicutes	M	Outer membrane protein, OMP85 family	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS1_k127_6596555_0	580340.Tlie_0063	8.795e-75	260.0	COG1322@1|root,COG1322@2|Bacteria,3T9XJ@508458|Synergistetes	508458|Synergistetes	S	PFAM RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
LZS1_k127_6596555_1	1089550.ATTH01000001_gene176	6.81e-10	73.0	COG2067@1|root,COG2067@2|Bacteria,4NHNC@976|Bacteroidetes,1FK4U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	penicillin-binding protein	porQ	-	-	-	-	-	-	-	-	-	-	-	PorP_SprF
LZS1_k127_6596555_2	880073.Calab_1286	0.0006786	54.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
LZS1_k127_6598352_6	1270196.JCKI01000009_gene3400	0.0003895	51.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,1IRA8@117747|Sphingobacteriia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
LZS1_k127_6598352_4	234267.Acid_7083	5.001e-39	168.0	COG1778@1|root,COG1778@2|Bacteria,3Y5BY@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
LZS1_k127_6598352_0	685778.AORL01000010_gene2673	3.511e-224	727.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,2KCZJ@204457|Sphingomonadales	204457|Sphingomonadales	G	Phosphoglucose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	PGI,TAL_FSA
LZS1_k127_6598352_3	661478.OP10G_4092	1.607e-48	177.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2621	LacAB_rpiB
LZS1_k127_6598352_5	593117.TGAM_0381	1.397e-09	69.0	COG2971@1|root,arCOG03659@2157|Archaea,2Y02S@28890|Euryarchaeota	28890|Euryarchaeota	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	2.7.1.59	ko:K00884	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	BcrAD_BadFG
LZS1_k127_6598352_1	574087.Acear_0218	2.708e-54	215.0	COG0457@1|root,COG2385@1|root,COG0457@2|Bacteria,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,3WABF@53433|Halanaerobiales	186801|Clostridia	D	TIGRFAM SpoIID LytB domain	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
LZS1_k127_6598352_2	448385.sce4763	8.764e-50	182.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2X37C@28221|Deltaproteobacteria,2YUQZ@29|Myxococcales	28221|Deltaproteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
LZS1_k127_6617796_3	243231.GSU3075	1.063e-44	169.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
LZS1_k127_6617796_0	644966.Tmar_0865	5.137e-121	406.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WCXE@538999|Clostridiales incertae sedis	186801|Clostridia	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS1_k127_6617796_2	404589.Anae109_3880	2.191e-73	266.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2YXRU@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS1_k127_6617796_1	582899.Hden_0240	8.843e-95	320.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,3N66M@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
LZS1_k127_6626712_6	1464048.JNZS01000004_gene1285	2.909e-11	74.0	COG0644@1|root,COG0644@2|Bacteria,2GMH9@201174|Actinobacteria,4DBY8@85008|Micromonosporales	201174|Actinobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS1_k127_6626712_1	1341151.ASZU01000010_gene1848	2.141e-68	254.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,27B3Q@186824|Thermoactinomycetaceae	91061|Bacilli	Q	Chalcone and stilbene synthases, N-terminal domain	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
LZS1_k127_6626712_4	671143.DAMO_0701	5.251e-24	110.0	COG0500@1|root,COG2226@2|Bacteria,2NRU8@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
LZS1_k127_6626712_5	370438.PTH_0856	9.418e-18	94.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia,2629Q@186807|Peptococcaceae	186801|Clostridia	M	PFAM Transglycosylase SLT domain	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
LZS1_k127_6626712_2	1234364.AMSF01000005_gene762	2.444e-60	215.0	COG1225@1|root,COG1225@2|Bacteria,1RGA7@1224|Proteobacteria,1S5HI@1236|Gammaproteobacteria,1X8HC@135614|Xanthomonadales	135614|Xanthomonadales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS1_k127_6626712_0	649638.Trad_0638	3.809e-226	714.0	COG1132@1|root,COG1132@2|Bacteria,1WMBB@1297|Deinococcus-Thermus	2|Bacteria	V	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS1_k127_6626712_3	29730.Gorai.006G223900.1	1.7e-37	141.0	COG0499@1|root,KOG1370@2759|Eukaryota,37R1E@33090|Viridiplantae,3GGCM@35493|Streptophyta	35493|Streptophyta	H	adenosylhomocysteinase	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS1_k127_6634441_7	42256.RradSPS_2004	1.952e-43	179.0	COG4398@1|root,COG4398@2|Bacteria,2I3VH@201174|Actinobacteria,4CQGG@84995|Rubrobacteria	84995|Rubrobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
LZS1_k127_6634441_13	941449.dsx2_1651	4.478e-07	63.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2M8CA@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
LZS1_k127_6634441_3	382464.ABSI01000011_gene2704	8.511e-79	283.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,2ITV3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Quinolinate synthetase A protein	-	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
LZS1_k127_6634441_8	1196323.ALKF01000190_gene5463	3.027e-43	167.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,26SCR@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	ugpQ_2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
LZS1_k127_6634441_6	429009.Adeg_1471	1.517e-51	192.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,42GGH@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
LZS1_k127_6634441_11	1329516.JPST01000005_gene1362	3.76e-21	96.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,27C7R@186824|Thermoactinomycetaceae	91061|Bacilli	O	NifU-like domain	yutI	-	-	-	-	-	-	-	-	-	-	-	NifU
LZS1_k127_6634441_10	525904.Tter_1700	3.793e-25	111.0	COG1959@1|root,COG1959@2|Bacteria,2NPZX@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS1_k127_6634441_12	756272.Plabr_3341	1.175e-18	96.0	COG2146@1|root,COG2151@1|root,COG2146@2|Bacteria,COG2151@2|Bacteria,2J020@203682|Planctomycetes	203682|Planctomycetes	P	metal-sulfur cluster biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P,Rieske
LZS1_k127_6634441_9	1183438.GKIL_1934	1.367e-29	124.0	COG0822@1|root,COG0822@2|Bacteria,1G590@1117|Cyanobacteria	1117|Cyanobacteria	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
LZS1_k127_6634441_1	266117.Rxyl_0166	8.267e-141	459.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CPE2@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase class-V	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
LZS1_k127_6634441_5	215803.DB30_6994	8.694e-63	236.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2WN3M@28221|Deltaproteobacteria,2YY27@29|Myxococcales	28221|Deltaproteobacteria	O	Uncharacterized protein family (UPF0051)	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
LZS1_k127_6634441_2	697282.Mettu_2997	2.077e-115	376.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1XE5C@135618|Methylococcales	135618|Methylococcales	O	ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
LZS1_k127_6634441_0	1382359.JIAL01000001_gene678	2.572e-252	784.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
LZS1_k127_6634441_14	398720.MED217_04742	8.539e-05	53.0	COG2885@1|root,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1HXNY@117743|Flavobacteriia,2XJR6@283735|Leeuwenhoekiella	976|Bacteroidetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40
LZS1_k127_6634441_4	292459.STH1268	6.211e-67	242.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
LZS1_k127_6637872_4	1121918.ARWE01000001_gene287	2.512e-10	63.0	COG1143@1|root,COG1143@2|Bacteria,1PJGD@1224|Proteobacteria,42U1E@68525|delta/epsilon subdivisions,2X28P@28221|Deltaproteobacteria,43UKJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
LZS1_k127_6637872_1	56780.SYN_02762	1.733e-64	232.0	COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
LZS1_k127_6637872_2	290397.Adeh_1049	2.627e-61	235.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
LZS1_k127_6637872_3	1353529.M899_0369	2.346e-18	90.0	2C8BN@1|root,32RKS@2|Bacteria,1N7Z0@1224|Proteobacteria,42WEU@68525|delta/epsilon subdivisions,2WS8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6637872_0	246197.MXAN_1795	1.084e-106	350.0	2BRF1@1|root,32KDW@2|Bacteria,1Q2SY@1224|Proteobacteria,438ER@68525|delta/epsilon subdivisions,2X3PP@28221|Deltaproteobacteria,2YWSS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6640295_0	378806.STAUR_5874	2.955e-105	351.0	COG0132@1|root,COG0132@2|Bacteria,1MYAE@1224|Proteobacteria,438QP@68525|delta/epsilon subdivisions,2X92A@28221|Deltaproteobacteria,2YXIK@29|Myxococcales	28221|Deltaproteobacteria	H	Domain of unknown function (DUF1611_C) P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611
LZS1_k127_6640295_2	290397.Adeh_0171	1.013e-82	290.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2YTTI@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS1_k127_6640295_1	518766.Rmar_0947	1.589e-91	329.0	COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1FJWU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS1_k127_6640295_3	518766.Rmar_0946	3.594e-74	270.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,1FJUC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the ATCase OTCase family	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.11,2.1.3.9	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245,R08937	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS1_k127_6654440_11	1120985.AUMI01000014_gene858	3.082e-16	83.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,4H2N6@909932|Negativicutes	909932|Negativicutes	G	Transketolase, pyridine binding domain protein	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS1_k127_6654440_2	370438.PTH_2750	2.645e-99	336.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,2607I@186807|Peptococcaceae	186801|Clostridia	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
LZS1_k127_6654440_7	1173027.Mic7113_1218	1.317e-53	204.0	COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria,1H9A9@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
LZS1_k127_6654440_4	1345697.M493_11910	1.217e-72	256.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
LZS1_k127_6654440_1	324057.Pjdr2_2337	2.953e-116	388.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,26QE9@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
LZS1_k127_6654440_5	755731.Clo1100_0282	6.915e-67	235.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,36DZ9@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
LZS1_k127_6654440_10	401053.AciPR4_0756	1.041e-16	89.0	COG0664@1|root,COG0664@2|Bacteria,3Y4IX@57723|Acidobacteria,2JJ9U@204432|Acidobacteriia	204432|Acidobacteriia	K	cyclic nucleotide-binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS1_k127_6654440_15	756272.Plabr_3415	1.98e-05	57.0	COG0457@1|root,COG0457@2|Bacteria	756272.Plabr_3415|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6654440_3	395493.BegalDRAFT_1646	7.335e-97	342.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria,463UI@72273|Thiotrichales	72273|Thiotrichales	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
LZS1_k127_6654440_6	880073.Calab_3665	5.213e-56	209.0	COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
LZS1_k127_6654440_8	1038860.AXAP01000004_gene5135	6.521e-27	115.0	COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,2UBW9@28211|Alphaproteobacteria,3JYZP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1304)	MA20_23345	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
LZS1_k127_6654440_13	862908.BMS_0283	1.902e-09	67.0	COG3137@1|root,COG3137@2|Bacteria,1N2DE@1224|Proteobacteria,42W9S@68525|delta/epsilon subdivisions,2MT9W@213481|Bdellovibrionales,2WTC1@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
LZS1_k127_6654440_12	1262449.CP6013_3111	1.604e-11	72.0	COG1309@1|root,COG1309@2|Bacteria,1TRSH@1239|Firmicutes,25B0B@186801|Clostridia,36WJZ@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
LZS1_k127_6654440_14	1123518.ARWI01000001_gene104	6.033e-08	66.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,460ES@72273|Thiotrichales	72273|Thiotrichales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340,ko:K12538	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00328,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,1.B.17.1,2.A.6.2	-	-	OEP
LZS1_k127_6654440_0	264462.Bd0888	0.0	1035.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2MSRN@213481|Bdellovibrionales,2WJ8D@28221|Deltaproteobacteria	213481|Bdellovibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS1_k127_6654440_9	929712.KI912613_gene1508	2.565e-26	124.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS1_k127_6654440_16	1121468.AUBR01000011_gene2506	0.0002281	47.0	COG5662@1|root,COG5662@2|Bacteria,1VC8Y@1239|Firmicutes,24NRN@186801|Clostridia,42GY2@68295|Thermoanaerobacterales	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
LZS1_k127_6668466_0	497964.CfE428DRAFT_4581	6.646e-162	535.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
LZS1_k127_6674540_3	349161.Dred_2286	1.59e-32	133.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS1_k127_6674540_2	4792.ETI52215	1.292e-80	274.0	COG2057@1|root,KOG3822@2759|Eukaryota,3Q7HA@4776|Peronosporales	4776|Peronosporales	C	Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate	-	-	2.8.3.5	ko:K01027	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS1_k127_6674540_1	1382303.JPOM01000001_gene1767	5.291e-85	287.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,2KF55@204458|Caulobacterales	204458|Caulobacterales	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	-	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS1_k127_6674540_0	1379698.RBG1_1C00001G1854	2.71e-148	477.0	COG0192@1|root,COG0192@2|Bacteria,2NNYF@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
LZS1_k127_6784272_0	1173026.Glo7428_0294	7.05e-198	638.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria	1117|Cyanobacteria	EU	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
LZS1_k127_6784272_1	765869.BDW_04600	2.806e-34	135.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,430NN@68525|delta/epsilon subdivisions,2MT6T@213481|Bdellovibrionales,2WVYS@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
LZS1_k127_6798737_1	1211579.PP4_43940	0.0006968	44.0	COG1196@1|root,COG1196@2|Bacteria,1R5S5@1224|Proteobacteria,1RQND@1236|Gammaproteobacteria,1YYEV@136845|Pseudomonas putida group	1236|Gammaproteobacteria	D	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6798737_0	1210884.HG799463_gene9843	0.0	1024.0	COG3256@1|root,COG3256@2|Bacteria,2J2IF@203682|Planctomycetes	203682|Planctomycetes	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
LZS1_k127_6811193_0	566461.SSFG_02212	0.0009232	51.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS1_k127_6831444_8	1205910.B005_3769	4.922e-06	57.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS1_k127_6831444_1	309801.trd_A0816	1.439e-65	243.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
LZS1_k127_6831444_0	395495.Lcho_1398	3.819e-103	361.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KN02@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS1_k127_6831444_5	760568.Desku_1744	2.037e-38	159.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,25BWB@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
LZS1_k127_6831444_7	411477.PARMER_03100	2.377e-17	99.0	COG4797@1|root,COG4797@2|Bacteria,4PKQS@976|Bacteroidetes,2FP69@200643|Bacteroidia,2322Y@171551|Porphyromonadaceae	976|Bacteroidetes	S	Motility related/secretion protein	sprA	-	-	-	-	-	-	-	-	-	-	-	SprA_N
LZS1_k127_6831444_4	439235.Dalk_2704	4.377e-61	217.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,42RFG@68525|delta/epsilon subdivisions,2WPKN@28221|Deltaproteobacteria,2MK0P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
LZS1_k127_6831444_2	1038859.AXAU01000007_gene5811	2.253e-62	224.0	COG0702@1|root,COG0702@2|Bacteria,1R8K0@1224|Proteobacteria,2TS4I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
LZS1_k127_6831444_3	580332.Slit_1776	4.273e-62	229.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	Bac_surface_Ag
LZS1_k127_6831444_6	644966.Tmar_0336	7.063e-31	130.0	COG0500@1|root,COG1547@1|root,COG1547@2|Bacteria,COG2226@2|Bacteria,1V45D@1239|Firmicutes	1239|Firmicutes	Q	SAM-dependent methyltransferase	ubiE7	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS1_k127_6869426_3	748449.Halha_2398	1.351e-44	171.0	COG1216@1|root,COG1216@2|Bacteria,1UIHC@1239|Firmicutes,25F9A@186801|Clostridia,3WADS@53433|Halanaerobiales	186801|Clostridia	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_6869426_4	760568.Desku_3298	1.551e-43	172.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,261SN@186807|Peptococcaceae	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS1_k127_6869426_2	903818.KI912269_gene362	2.342e-48	186.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	rfaQ	-	-	ko:K02841,ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS1_k127_6869426_1	401526.TcarDRAFT_0106	4.346e-63	241.0	COG1663@1|root,COG1663@2|Bacteria,1TWGA@1239|Firmicutes,4H97G@909932|Negativicutes	909932|Negativicutes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glycos_transf_N,LpxK
LZS1_k127_6869426_6	439235.Dalk_0281	1.41e-23	117.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WNBB@28221|Deltaproteobacteria,2MK5J@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
LZS1_k127_6869426_0	671143.DAMO_0267	3.285e-86	297.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
LZS1_k127_6869426_5	1110502.TMO_3191	9.661e-27	123.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,2JPST@204441|Rhodospirillales	204441|Rhodospirillales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
LZS1_k127_6879892_0	211165.AJLN01000035_gene2726	3.412e-256	801.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JJJ8@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS1_k127_6882962_0	1128398.Curi_c16270	1.167e-58	207.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,267UY@186813|unclassified Clostridiales	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
LZS1_k127_6882962_1	331869.BAL199_21229	6.434e-40	160.0	COG3719@1|root,COG3719@2|Bacteria,1NRPM@1224|Proteobacteria,2U24Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Belongs to the RNase T2 family	-	-	3.1.27.1	ko:K01166	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_T2
LZS1_k127_690368_1	316067.Geob_1202	3.454e-55	201.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2WUGK@28221|Deltaproteobacteria,43U2B@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_1671	Transgly,Transpeptidase
LZS1_k127_690368_0	743721.Psesu_1928	5.811e-109	366.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1X3FD@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS1_k127_6908714_4	880073.Calab_1612	8.943e-21	105.0	COG0509@1|root,COG0745@1|root,COG0509@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H,Response_reg
LZS1_k127_6908714_0	1191523.MROS_1569	1.407e-223	709.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS1_k127_6908714_3	1191523.MROS_1570	1.12e-43	168.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2
LZS1_k127_6908714_1	1191523.MROS_1571	5.35e-170	554.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hybB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	iAPECO1_1312.APECO1_3427,iE2348C_1286.E2348C_3282,iECABU_c1320.ECABU_c34010,iECOK1_1307.ECOK1_3414,iECS88_1305.ECS88_3377,iUMN146_1321.UM146_01380,iUTI89_1310.UTI89_C3417	NrfD
LZS1_k127_6908714_2	1191523.MROS_1572	1.377e-127	414.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7
LZS1_k127_6922567_1	945713.IALB_2052	2.234e-10	70.0	COG0457@1|root,COG0457@2|Bacteria	945713.IALB_2052|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6922567_3	1123008.KB905693_gene1372	2.644e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22XN2@171551|Porphyromonadaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
LZS1_k127_6922567_0	448385.sce0007	4.107e-33	133.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,2YVE5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS1_k127_6922567_2	1051501.AYTL01000027_gene566	1.453e-09	63.0	COG4405@1|root,COG4405@2|Bacteria,1VDG5@1239|Firmicutes,4HM8P@91061|Bacilli,1ZKFH@1386|Bacillus	91061|Bacilli	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
LZS1_k127_6929672_2	335543.Sfum_3126	1.524e-38	158.0	COG3394@1|root,COG3394@2|Bacteria,1PP3A@1224|Proteobacteria,42R6K@68525|delta/epsilon subdivisions,2WN1Q@28221|Deltaproteobacteria,2MRXE@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	YdjC-like protein	hpnK	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
LZS1_k127_6929672_3	1122604.JONR01000001_gene1865	1.366e-20	103.0	COG0392@1|root,COG0392@2|Bacteria,1PHVH@1224|Proteobacteria,1S0ZE@1236|Gammaproteobacteria,1X991@135614|Xanthomonadales	135614|Xanthomonadales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
LZS1_k127_6929672_1	269799.Gmet_2815	3.312e-72	259.0	COG1215@1|root,COG1215@2|Bacteria,1PC79@1224|Proteobacteria,42QYP@68525|delta/epsilon subdivisions,2X6HG@28221|Deltaproteobacteria,43UDX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	hpnI	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
LZS1_k127_6929672_0	1380394.JADL01000005_gene5573	1.806e-200	635.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TRFJ@28211|Alphaproteobacteria,2JRB5@204441|Rhodospirillales	204441|Rhodospirillales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS1_k127_6929672_5	309801.trd_1637	5.082e-06	58.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,27XPY@189775|Thermomicrobia	189775|Thermomicrobia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
LZS1_k127_6929672_4	404589.Anae109_1613	1.97e-08	57.0	COG4262@1|root,COG4262@2|Bacteria,1PD57@1224|Proteobacteria,43EWI@68525|delta/epsilon subdivisions,2X2BM@28221|Deltaproteobacteria,2YZ47@29|Myxococcales	28221|Deltaproteobacteria	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
LZS1_k127_6939852_3	1054213.HMPREF9946_04520	8.725e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,1RK4Q@1224|Proteobacteria,2UBBB@28211|Alphaproteobacteria,2JSKY@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_9
LZS1_k127_6939852_2	536019.Mesop_3384	1.367e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_6939852_0	1321778.HMPREF1982_00647	6.115e-20	105.0	28N78@1|root,2ZBBY@2|Bacteria,1VWWN@1239|Firmicutes,24QA9@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
LZS1_k127_6939852_1	316057.RPD_2468	4.54e-13	82.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TRW5@28211|Alphaproteobacteria,3JR0X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Sel1,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS1_k127_6948645_2	338969.Rfer_0415	1.812e-41	158.0	COG1495@1|root,COG1495@2|Bacteria,1N2C1@1224|Proteobacteria,2VTN0@28216|Betaproteobacteria,4AICZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	Disulfide bond formation protein DsbB	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
LZS1_k127_6948645_1	1123326.JFBL01000010_gene743	2.404e-60	218.0	COG1651@1|root,COG1651@2|Bacteria,1MVS2@1224|Proteobacteria,42UNJ@68525|delta/epsilon subdivisions,2YRUK@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
LZS1_k127_6948645_0	525904.Tter_1809	3.922e-236	738.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	M1-534	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored,SLH
LZS1_k127_6953473_1	266117.Rxyl_3161	2.085e-05	55.0	COG0457@1|root,COG0457@2|Bacteria	266117.Rxyl_3161|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_6953473_0	639030.JHVA01000001_gene297	3.937e-14	80.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria,2JIVB@204432|Acidobacteriia	204432|Acidobacteriia	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
LZS1_k127_6956213_1	1121930.AQXG01000014_gene386	7.351e-62	231.0	COG1834@1|root,COG1834@2|Bacteria	2|Bacteria	E	dimethylargininase activity	-	GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Amidinotransf,Saccharop_dh_N
LZS1_k127_6956213_0	452637.Oter_1789	5.368e-84	301.0	COG2933@1|root,COG2933@2|Bacteria,46YM6@74201|Verrucomicrobia,3K7KR@414999|Opitutae	414999|Opitutae	J	FtsJ-like methyltransferase	-	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
LZS1_k127_6978419_1	439235.Dalk_2300	1.415e-34	146.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9,Response_reg
LZS1_k127_6978419_0	96561.Dole_2898	1.941e-73	264.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
LZS1_k127_6981512_0	1121405.dsmv_0798	1.005e-78	271.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,2MJK2@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_6981512_4	1304872.JAGC01000003_gene2656	0.0004293	46.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,2M8FM@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
LZS1_k127_6981512_1	926554.KI912650_gene4179	3.991e-62	220.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
LZS1_k127_6981512_2	414684.RC1_3454	3.683e-22	111.0	COG0517@1|root,COG0517@2|Bacteria,1NMH1@1224|Proteobacteria,2U9D8@28211|Alphaproteobacteria,2JT6V@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS1_k127_6981512_3	1123508.JH636440_gene2261	9.584e-14	84.0	COG2941@1|root,COG2941@2|Bacteria	2|Bacteria	H	ubiquinone biosynthetic process	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
LZS1_k127_6982777_0	1192034.CAP_3553	1.188e-81	287.0	COG0535@1|root,COG0535@2|Bacteria,1R4SH@1224|Proteobacteria,42NZR@68525|delta/epsilon subdivisions,2WKQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_6982777_3	316058.RPB_0971	5.053e-12	78.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,2TT37@28211|Alphaproteobacteria,3JU1N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
LZS1_k127_6982777_4	697329.Rumal_0522	2.243e-09	71.0	COG2710@1|root,COG2710@2|Bacteria,1TP8Z@1239|Firmicutes,249HR@186801|Clostridia,3WHZD@541000|Ruminococcaceae	186801|Clostridia	C	Nitrogenase component 1	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
LZS1_k127_6982777_1	456442.Mboo_2008	1.938e-59	229.0	COG1348@1|root,arCOG00590@2157|Archaea,2XUNI@28890|Euryarchaeota,2N9FB@224756|Methanomicrobia	224756|Methanomicrobia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	nifH-1	-	1.18.6.1,6.3.3.7	ko:K02588,ko:K21610	ko00625,ko00860,ko00910,ko01100,ko01120,map00625,map00860,map00910,map01100,map01120	M00175,M00836	R05185,R05496,R11628	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
LZS1_k127_6982777_2	1280664.AUIX01000009_gene3948	2.221e-47	194.0	COG1348@1|root,COG1348@2|Bacteria,1TPXR@1239|Firmicutes,247KJ@186801|Clostridia,4BWTH@830|Butyrivibrio	186801|Clostridia	P	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
LZS1_k127_6994478_0	330214.NIDE2086	8.125e-95	337.0	COG1074@1|root,COG1074@2|Bacteria,3J16M@40117|Nitrospirae	40117|Nitrospirae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS1_k127_7029486_4	252305.OB2597_03479	2.882e-19	89.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,2PD38@252301|Oceanicola	28211|Alphaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS1_k127_7029486_2	401526.TcarDRAFT_1423	9.306e-54	199.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4H2VA@909932|Negativicutes	909932|Negativicutes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
LZS1_k127_7029486_0	292.DM42_1398	3.498e-129	424.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,1K26U@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
LZS1_k127_7029486_1	634452.APA01_26070	3.014e-63	235.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria,2JPGC@204441|Rhodospirillales	204441|Rhodospirillales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
LZS1_k127_7029486_3	1429046.RR21198_3519	3.637e-25	115.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4FZVS@85025|Nocardiaceae	201174|Actinobacteria	G	ROK family	glkA	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS1_k127_7031782_5	349124.Hhal_1831	2.609e-05	49.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
LZS1_k127_7031782_3	243231.GSU1923	6.586e-30	136.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,43TT8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted permease YjgP/YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
LZS1_k127_7031782_4	443143.GM18_0693	4.71e-24	115.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,43T2W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
LZS1_k127_7031782_0	1144275.COCOR_06542	7.556e-167	537.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria,2YUYT@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS1_k127_7031782_1	1089548.KI783301_gene388	1.536e-108	366.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1V01J@1239|Firmicutes,4HEV4@91061|Bacilli	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS1_k127_7031782_2	608538.HTH_0620	1.204e-79	280.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I
LZS1_k127_7033777_1	1121439.dsat_2168	5.921e-58	219.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2X5HP@28221|Deltaproteobacteria,2MG6D@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
LZS1_k127_7033777_4	1121861.KB899920_gene2880	7.812e-08	65.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,2TV39@28211|Alphaproteobacteria,2JR6C@204441|Rhodospirillales	204441|Rhodospirillales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS1_k127_7033777_3	227882.SAV_4516	1.132e-11	78.0	COG5542@1|root,COG5542@2|Bacteria,2GJQF@201174|Actinobacteria	201174|Actinobacteria	NT	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
LZS1_k127_7033777_2	517418.Ctha_0356	3.843e-12	77.0	COG0095@1|root,COG0095@2|Bacteria,1FDZ6@1090|Chlorobi	1090|Chlorobi	H	PFAM biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
LZS1_k127_7033777_0	1173024.KI912153_gene315	4.16e-222	695.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1JIBX@1189|Stigonemataceae	1117|Cyanobacteria	E	Glycine cleavage system P-protein	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
LZS1_k127_705368_0	1121451.DESAM_10206	2.874e-17	97.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
LZS1_k127_705368_1	1396418.BATQ01000099_gene5575	3.314e-07	62.0	COG0388@1|root,COG0388@2|Bacteria,46ZGG@74201|Verrucomicrobia,2IUQ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
LZS1_k127_7060833_1	247490.KSU1_D0161	2.079e-39	164.0	COG3857@1|root,COG3857@2|Bacteria,2IZEK@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,Exonuc_V_gamma,PDDEXK_1,UvrD_C
LZS1_k127_7060833_0	391625.PPSIR1_29036	2.4e-87	310.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
LZS1_k127_7060833_2	265072.Mfla_1137	4.853e-31	128.0	COG0782@1|root,COG0782@2|Bacteria,1RHU5@1224|Proteobacteria,2W3NT@28216|Betaproteobacteria,2KMUI@206350|Nitrosomonadales	206350|Nitrosomonadales	K	PFAM transcription elongation factor GreA GreB	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
LZS1_k127_7060833_3	1231190.NA8A_08859	1.438e-16	86.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,43J0S@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Probable molybdopterin binding domain	MA20_09420	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,NTP_transf_3
LZS1_k127_7063916_4	555779.Dthio_PD3723	2.951e-12	72.0	COG1373@1|root,COG1373@2|Bacteria,1R8TB@1224|Proteobacteria,42YR2@68525|delta/epsilon subdivisions,2WUJS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
LZS1_k127_7063916_1	1123508.JH636440_gene2642	2.208e-75	281.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,2IZV4@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
LZS1_k127_7063916_3	452637.Oter_0039	4.177e-38	147.0	COG0745@1|root,COG0745@2|Bacteria	452637.Oter_0039|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7063916_0	234267.Acid_1818	6.152e-241	762.0	COG3590@1|root,COG3590@2|Bacteria,3Y31X@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase M13	-	-	3.4.24.71	ko:K01415	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
LZS1_k127_7063916_2	264732.Moth_0371	5.312e-75	263.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,249II@186801|Clostridia,42FVW@68295|Thermoanaerobacterales	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS1_k127_7083486_4	1144275.COCOR_07182	9.907e-53	190.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,2YV5F@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS1_k127_7083486_8	862908.BMS_3380	1.55e-10	67.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
LZS1_k127_7083486_6	1276756.AUEX01000005_gene2845	2.815e-25	111.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,4AE4Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS1_k127_7083486_5	518766.Rmar_0611	2.579e-36	153.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS1_k127_7083486_1	1192034.CAP_2100	1.646e-68	258.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,42T8N@68525|delta/epsilon subdivisions,2WZ91@28221|Deltaproteobacteria,2Z1M2@29|Myxococcales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
LZS1_k127_7083486_3	316067.Geob_0358	6.194e-53	193.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2WPAC@28221|Deltaproteobacteria,43UU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
LZS1_k127_7083486_7	1117315.AHCA01000001_gene2433	1.489e-21	100.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,1S8UW@1236|Gammaproteobacteria,2Q4FN@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
LZS1_k127_7083486_0	330214.NIDE4188	1.432e-130	441.0	28J7E@1|root,2Z92U@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
LZS1_k127_7083486_2	316067.Geob_3261	5.157e-55	211.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,43AJV@68525|delta/epsilon subdivisions,2X601@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
LZS1_k127_7083486_9	713586.KB900536_gene2577	2.49e-05	54.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1WX6D@135613|Chromatiales	135613|Chromatiales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS1_k127_7107395_0	497964.CfE428DRAFT_1132	1.96e-184	581.0	COG3303@1|root,COG3303@2|Bacteria,46UP1@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
LZS1_k127_7107395_2	1121406.JAEX01000003_gene1586	4.142e-32	136.0	COG0265@1|root,COG3016@1|root,COG0265@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WQAR@28221|Deltaproteobacteria,2MG9S@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	SMART PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2,Peptidase_M1
LZS1_k127_7107395_5	298655.KI912266_gene3286	7.286e-08	65.0	2BK9Q@1|root,32EPW@2|Bacteria,2H0WI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7107395_3	1396418.BATQ01000058_gene93	2.86e-26	121.0	COG0500@1|root,COG0500@2|Bacteria,46Z44@74201|Verrucomicrobia,2IUZB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS1_k127_7107395_1	1123368.AUIS01000030_gene1247	1.806e-82	289.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	mechanosensitive ion channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
LZS1_k127_7107395_4	390989.JOEG01000021_gene2640	1.416e-12	74.0	COG0222@1|root,COG0222@2|Bacteria,2HM1I@201174|Actinobacteria,4DGAD@85008|Micromonosporales	201174|Actinobacteria	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7107769_6	290318.Cvib_0170	2.005e-13	78.0	COG1214@1|root,COG1214@2|Bacteria,1FE0D@1090|Chlorobi	1090|Chlorobi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
LZS1_k127_7107769_4	644966.Tmar_0266	2.493e-23	115.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3WCKY@538999|Clostridiales incertae sedis	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
LZS1_k127_7107769_1	477974.Daud_0471	2.123e-56	211.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
LZS1_k127_7107769_2	290397.Adeh_1905	6.138e-42	160.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,437B2@68525|delta/epsilon subdivisions,2X2FR@28221|Deltaproteobacteria,2Z0QW@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
LZS1_k127_7107769_3	1121439.dsat_2145	3.289e-24	106.0	COG2929@1|root,COG2929@2|Bacteria,1N8PW@1224|Proteobacteria,42V50@68525|delta/epsilon subdivisions,2WRZB@28221|Deltaproteobacteria,2MFNF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
LZS1_k127_7107769_5	237368.SCABRO_00872	8.442e-22	98.0	COG5304@1|root,COG5304@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
LZS1_k127_7107769_0	1163407.UU7_16992	1.148e-110	372.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1X3FD@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS1_k127_7107769_7	439235.Dalk_5077	4.127e-06	48.0	2DNYA@1|root,32ZS5@2|Bacteria,1NCZE@1224|Proteobacteria,42W1I@68525|delta/epsilon subdivisions,2WS5F@28221|Deltaproteobacteria,2MPCZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1877
LZS1_k127_7117086_0	1499967.BAYZ01000016_gene6509	1.889e-65	236.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
LZS1_k127_7117086_2	1449126.JQKL01000056_gene2268	1.736e-46	182.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,267X8@186813|unclassified Clostridiales	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
LZS1_k127_7117086_1	1254432.SCE1572_10325	1.137e-63	229.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2YUZ3@29|Myxococcales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
LZS1_k127_7118573_2	888060.HMPREF9081_0862	1.633e-47	175.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H2HH@909932|Negativicutes	909932|Negativicutes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS1_k127_7118573_1	330214.NIDE3403	1.73e-53	194.0	COG2095@1|root,COG2095@2|Bacteria,3J0UZ@40117|Nitrospirae	40117|Nitrospirae	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
LZS1_k127_7118573_5	398578.Daci_2448	2.364e-23	116.0	2DC00@1|root,2ZC4V@2|Bacteria,1RBPR@1224|Proteobacteria,2W3QT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7118573_0	479432.Sros_6500	2.595e-166	565.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,4EI6C@85012|Streptosporangiales	201174|Actinobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS1_k127_7118573_4	864051.BurJ1DRAFT_1272	3.579e-25	121.0	COG2244@1|root,COG2244@2|Bacteria,1R6ME@1224|Proteobacteria,2VNGZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	rfbE	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS1_k127_7118573_3	886293.Sinac_1743	8.797e-41	162.0	COG0438@1|root,COG0438@2|Bacteria,2J274@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
LZS1_k127_7136518_0	1056816.JAFQ01000004_gene2808	1.36e-83	295.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4FWXS@85025|Nocardiaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
LZS1_k127_7136518_1	290315.Clim_1272	2.628e-47	177.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	ddpX	-	3.2.1.52,3.4.13.22	ko:K01207,ko:K08641	ko00520,ko00531,ko01100,ko01501,ko01502,ko02020,map00520,map00531,map01100,map01501,map01502,map02020	M00628,M00651	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
LZS1_k127_7136518_4	1502770.JQMG01000001_gene2057	7.049e-06	49.0	2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7136518_3	883096.HMPREF9699_01029	1.533e-11	73.0	COG1051@1|root,COG1051@2|Bacteria,4NR5C@976|Bacteroidetes,1I3JR@117743|Flavobacteriia	976|Bacteroidetes	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS1_k127_7136518_2	314278.NB231_14198	4.573e-27	115.0	COG0491@1|root,COG0491@2|Bacteria,1RGCD@1224|Proteobacteria,1S4WB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_5
LZS1_k127_7142564_4	926561.KB900619_gene2544	2.482e-33	137.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WABM@53433|Halanaerobiales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS1_k127_7142564_6	1150399.AQYK01000002_gene2690	1.415e-19	91.0	COG1254@1|root,COG1254@2|Bacteria,2HZJD@201174|Actinobacteria,4FQ1C@85023|Microbacteriaceae	201174|Actinobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
LZS1_k127_7142564_7	1415780.JPOG01000001_gene1556	4.608e-14	83.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1X6IC@135614|Xanthomonadales	135614|Xanthomonadales	K	MerR family transcriptional regulator	VL23_01195	-	-	-	-	-	-	-	-	-	-	-	MerR_1
LZS1_k127_7142564_8	1267535.KB906767_gene253	1.341e-13	79.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS1_k127_7142564_5	1499967.BAYZ01000157_gene585	1.995e-30	128.0	COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria	2|Bacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
LZS1_k127_7142564_2	478749.BRYFOR_06367	1.708e-62	227.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
LZS1_k127_7142564_3	1121468.AUBR01000051_gene1999	1.161e-34	141.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,42GMG@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
LZS1_k127_7142564_0	1341151.ASZU01000009_gene899	7.856e-90	329.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,27BNI@186824|Thermoactinomycetaceae	91061|Bacilli	S	GTP-binding GTPase Middle Region	hflX	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS1_k127_7142564_1	105559.Nwat_1114	5.245e-74	268.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,1T2R5@1236|Gammaproteobacteria,1WZ7X@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7142564_9	1378168.N510_00995	0.0002798	45.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes	1239|Firmicutes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
LZS1_k127_7153079_1	1123508.JH636456_gene146	2.201e-194	617.0	COG2217@1|root,COG2217@2|Bacteria,2IXAD@203682|Planctomycetes	203682|Planctomycetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS1_k127_7153079_8	314275.MADE_1016550	1.247e-05	53.0	COG4244@1|root,COG4244@2|Bacteria,1RF4K@1224|Proteobacteria,1S637@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
LZS1_k127_7153079_7	616991.JPOO01000003_gene109	1.161e-16	84.0	2CK2Q@1|root,303GN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7153079_0	404589.Anae109_4264	0.0	1482.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
LZS1_k127_7153079_4	1123519.PSJM300_10640	2.339e-64	236.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1YZQQ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cebB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23,HlyD_D4
LZS1_k127_7153079_5	237368.SCABRO_01554	1.187e-47	187.0	COG1538@1|root,COG1538@2|Bacteria,2IZPU@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS1_k127_7153079_2	1173026.Glo7428_4416	1.56e-78	283.0	COG0753@1|root,COG0753@2|Bacteria,1G4T1@1117|Cyanobacteria	1117|Cyanobacteria	P	Catalase	-	-	-	-	-	-	-	-	-	-	-	-	Catalase
LZS1_k127_7153079_3	439235.Dalk_1753	1.411e-75	264.0	COG0300@1|root,COG0623@1|root,COG0300@2|Bacteria,COG0623@2|Bacteria,1R090@1224|Proteobacteria,43CRU@68525|delta/epsilon subdivisions,2X7ZF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS1_k127_7153079_6	1192034.CAP_2447	3.701e-47	187.0	COG0332@1|root,COG0332@2|Bacteria,1RB9M@1224|Proteobacteria,42YNV@68525|delta/epsilon subdivisions,2WTQM@28221|Deltaproteobacteria,2YYYC@29|Myxococcales	28221|Deltaproteobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS1_k127_7157170_0	1232410.KI421428_gene1224	1.005e-310	978.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,43S5H@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	RNA polymerase I subunit A N-terminus	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
LZS1_k127_7167806_0	479432.Sros_4203	7.315e-16	94.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4ENKK@85012|Streptosporangiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
LZS1_k127_7188659_0	926692.AZYG01000047_gene2664	5.88e-123	410.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WANE@53433|Halanaerobiales	186801|Clostridia	L	Replicative DNA helicase	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
LZS1_k127_7188659_2	1379281.AVAG01000026_gene1610	5.03e-26	112.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,2MAU8@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
LZS1_k127_7188659_3	536232.CLM_4131	2.172e-20	94.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,36KGE@31979|Clostridiaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
LZS1_k127_7188659_1	1158318.ATXC01000001_gene1188	2.285e-26	114.0	COG0629@1|root,COG0629@2|Bacteria,2G55E@200783|Aquificae	200783|Aquificae	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS1_k127_7188659_4	742766.HMPREF9455_01224	2.062e-13	78.0	COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,2FSHK@200643|Bacteroidia,22Y4M@171551|Porphyromonadaceae	976|Bacteroidetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
LZS1_k127_7213167_1	306281.AJLK01000109_gene3106	1.955e-139	450.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria,1JHEV@1189|Stigonemataceae	1117|Cyanobacteria	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
LZS1_k127_7213167_6	382464.ABSI01000013_gene1636	6.657e-68	241.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS1_k127_7213167_4	344747.PM8797T_04695	3.947e-92	314.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K03406,ko:K21470	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01002,ko01011,ko02035	-	-	-	DUF4325,HATPase_c,HisKA_3
LZS1_k127_7213167_2	378806.STAUR_4782	5.425e-119	391.0	COG0010@1|root,COG0010@2|Bacteria,1RCQX@1224|Proteobacteria,42R4M@68525|delta/epsilon subdivisions,2X5RQ@28221|Deltaproteobacteria,2YYRW@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
LZS1_k127_7213167_3	1266925.JHVX01000010_gene1383	1.007e-97	332.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2VJ5C@28216|Betaproteobacteria,3740U@32003|Nitrosomonadales	28216|Betaproteobacteria	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS1_k127_7213167_9	251221.35214291	5.086e-29	134.0	COG1216@1|root,COG1216@2|Bacteria,1GQK0@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS1_k127_7213167_8	1380390.JIAT01000014_gene6289	4.117e-40	163.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
LZS1_k127_7213167_0	395961.Cyan7425_1965	1.444e-140	461.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
LZS1_k127_7213167_5	1121335.Clst_0008	7.059e-87	296.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3WGTZ@541000|Ruminococcaceae	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS1_k127_7213167_7	555079.Toce_2275	1.322e-63	229.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,42FPF@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
LZS1_k127_7213167_10	69042.WH5701_03034	1.104e-06	50.0	COG0136@1|root,COG0136@2|Bacteria,1G0E6@1117|Cyanobacteria,1GYKG@1129|Synechococcus	1117|Cyanobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS1_k127_7239406_1	247490.KSU1_C0978	1.17e-103	350.0	COG0550@1|root,COG0550@2|Bacteria,2IY53@203682|Planctomycetes	203682|Planctomycetes	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
LZS1_k127_7239406_2	635013.TherJR_1549	1.91e-66	239.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,260TU@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS1_k127_7239406_0	1150599.MPHLEI_10860	1.037e-134	441.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,232EC@1762|Mycobacteriaceae	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
LZS1_k127_7239406_3	671143.DAMO_2148	1.903e-32	131.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
LZS1_k127_7260021_3	1907.SGLAU_31710	0.0007128	53.0	COG3227@1|root,COG3227@2|Bacteria,2H48J@201174|Actinobacteria	201174|Actinobacteria	E	Thermolysin metallopeptidase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
LZS1_k127_7260021_1	1220534.B655_0694	2.597e-16	94.0	arCOG06557@1|root,arCOG06557@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7260021_2	35754.JNYJ01000043_gene4597	4.673e-10	71.0	COG1413@1|root,COG1413@2|Bacteria,2INKI@201174|Actinobacteria,4DHQ2@85008|Micromonosporales	201174|Actinobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
LZS1_k127_7260021_0	247490.KSU1_A0010	2.799e-27	119.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_24
LZS1_k127_7260359_0	1192034.CAP_2187	6.353e-120	404.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_7265726_4	743721.Psesu_1293	4.073e-40	151.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1X4C8@135614|Xanthomonadales	135614|Xanthomonadales	P	Belongs to the ABC transporter superfamily	ugpC	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
LZS1_k127_7265726_2	1487953.JMKF01000071_gene3385	1.861e-69	258.0	COG0395@1|root,COG0395@2|Bacteria,1G0CF@1117|Cyanobacteria,1H6X9@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Binding-protein-dependent transport system inner membrane component	ugpE	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS1_k127_7265726_1	459495.SPLC1_S081660	1.095e-71	262.0	COG1175@1|root,COG1175@2|Bacteria,1G0YN@1117|Cyanobacteria,1H7ZN@1150|Oscillatoriales	1117|Cyanobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	ugpA	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS1_k127_7265726_0	1173026.Glo7428_1851	1.176e-101	347.0	COG1653@1|root,COG1653@2|Bacteria,1G0AA@1117|Cyanobacteria	1117|Cyanobacteria	G	ABC-type sugar transport system periplasmic component	ugpB	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
LZS1_k127_7265726_5	1517416.IDAT_02270	4.026e-35	145.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,2QG5R@267893|Idiomarinaceae	1236|Gammaproteobacteria	K	LysR family	nhaR	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
LZS1_k127_7265726_6	1201288.M900_0836	3.367e-25	112.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2MT4C@213481|Bdellovibrionales,2WNZS@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
LZS1_k127_7265726_3	1125863.JAFN01000001_gene2073	1.828e-67	244.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS1_k127_7269908_3	644966.Tmar_0093	4.061e-05	51.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3WDF1@538999|Clostridiales incertae sedis	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
LZS1_k127_7269908_2	301.JNHE01000019_gene4169	5.383e-67	245.0	COG2035@1|root,COG2035@2|Bacteria,1MXVI@1224|Proteobacteria,1RN4B@1236|Gammaproteobacteria,1YI4J@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
LZS1_k127_7269908_1	521674.Plim_0463	2.529e-180	579.0	COG2070@1|root,COG2070@2|Bacteria,2IX4J@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM PfaD family protein	-	-	-	-	-	-	-	-	-	-	-	-	NMO
LZS1_k127_7269908_0	338966.Ppro_3101	5.013e-289	917.0	COG0236@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,43W01@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,FabA,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
LZS1_k127_7271120_9	713586.KB900536_gene2577	1.008e-05	57.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RNQN@1236|Gammaproteobacteria,1WX6D@135613|Chromatiales	135613|Chromatiales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS1_k127_7271120_3	234267.Acid_2359	3.464e-45	176.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria	2|Bacteria	S	Radical SAM domain protein	-	-	-	ko:K15045	ko05164,map05164	-	-	-	ko00000,ko00001	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
LZS1_k127_7271120_6	1304872.JAGC01000005_gene1785	1.099e-15	81.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2MCMH@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
LZS1_k127_7271120_0	1267535.KB906767_gene4458	1.296e-175	579.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
LZS1_k127_7271120_8	644282.Deba_0974	3.287e-06	59.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
LZS1_k127_7271120_7	1210884.HG799464_gene11097	5.936e-10	68.0	COG2010@1|root,COG2010@2|Bacteria,2IXIX@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
LZS1_k127_7271120_2	886293.Sinac_6888	1.623e-56	216.0	COG0109@1|root,COG0109@2|Bacteria,2IYUU@203682|Planctomycetes	203682|Planctomycetes	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
LZS1_k127_7271120_5	671143.DAMO_1660	1.529e-24	115.0	COG1612@1|root,COG1612@2|Bacteria,2NQ3D@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259,ko:K03110	ko00190,ko00860,ko01100,ko01110,ko02020,ko02024,ko03060,ko03070,ko04714,map00190,map00860,map01100,map01110,map02020,map02024,map03060,map03070,map04714	M00154,M00335	R07412	RC00769	ko00000,ko00001,ko00002,ko02044,ko03029	3.A.5.1,3.A.5.2,3.A.5.7,3.D.4.4	-	-	COX15-CtaA
LZS1_k127_7271120_10	641491.DND132_3043	0.0003927	49.0	2EAMQ@1|root,334Q9@2|Bacteria,1NA2T@1224|Proteobacteria,42VC9@68525|delta/epsilon subdivisions,2WRD9@28221|Deltaproteobacteria,2MD2F@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	oxidase, subunit IV	coxD	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
LZS1_k127_7271120_4	478741.JAFS01000002_gene335	4.04e-40	161.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
LZS1_k127_7271120_1	497964.CfE428DRAFT_2230	3.522e-105	348.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
LZS1_k127_727806_4	1496688.ER33_14545	8.456e-05	46.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Abi,HTH_Crp_2,PrsW-protease,cNMP_binding
LZS1_k127_727806_3	1496688.ER33_14545	9.908e-09	63.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Abi,HTH_Crp_2,PrsW-protease,cNMP_binding
LZS1_k127_727806_2	1123508.JH636445_gene6801	8.973e-40	152.0	COG0629@1|root,COG0629@2|Bacteria,2IZJ8@203682|Planctomycetes	203682|Planctomycetes	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS1_k127_727806_0	1184267.A11Q_1967	2.088e-108	361.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,42QQG@68525|delta/epsilon subdivisions,2MTKR@213481|Bdellovibrionales,2WMXN@28221|Deltaproteobacteria	213481|Bdellovibrionales	G	Glucose / Sorbosone dehydrogenase	gdhB	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH,Ricin_B_lectin
LZS1_k127_727806_1	502025.Hoch_3203	1.783e-81	301.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2YX8P@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
LZS1_k127_7298757_5	1430331.EP10_01630	0.0002017	51.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1WEFC@129337|Geobacillus	91061|Bacilli	S	Tetratricopeptide repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
LZS1_k127_7298757_4	452637.Oter_1350	3.144e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,46Y0G@74201|Verrucomicrobia,3K8R1@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7298757_0	485913.Krac_4840	9.309e-58	209.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS1_k127_7298757_1	1120950.KB892749_gene3374	1.653e-45	174.0	COG5285@1|root,COG5285@2|Bacteria,2HZV9@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS1_k127_7298757_2	1303518.CCALI_01361	6.324e-39	159.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS1_k127_7298757_3	1122218.KB893663_gene1703	1.956e-07	59.0	COG0457@1|root,COG0457@2|Bacteria,1NG0U@1224|Proteobacteria,2U0YA@28211|Alphaproteobacteria,1JSA5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS1_k127_7299446_0	562970.Btus_0327	0.0	1136.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,2782J@186823|Alicyclobacillaceae	91061|Bacilli	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS1_k127_7299446_1	885272.JonanDRAFT_0853	1.648e-48	202.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3TAJY@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS1_k127_7299446_4	272557.APE_0028	0.0003097	55.0	COG0574@1|root,arCOG01114@2157|Archaea,2XS8V@28889|Crenarchaeota	28889|Crenarchaeota	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
LZS1_k127_7299446_2	1031288.AXAA01000001_gene2256	5.464e-06	55.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,36IRH@31979|Clostridiaceae	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS1_k127_7311459_3	1123070.KB899251_gene657	9.048e-24	102.0	COG5557@1|root,COG5557@2|Bacteria,46U15@74201|Verrucomicrobia,2ITS8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
LZS1_k127_7311459_0	1121413.JMKT01000008_gene1013	3.904e-73	271.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS1_k127_7311459_1	331869.BAL199_03804	3.277e-72	272.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2U1NG@28211|Alphaproteobacteria,4BQ49@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
LZS1_k127_7311459_2	471853.Bcav_0856	3.31e-25	114.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	4.2.3.1	ko:K01733,ko:K22010	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018,M00839	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	HAMP,HATPase_c,HTH_18,HisKA,Response_reg
LZS1_k127_7311459_4	1125863.JAFN01000001_gene579	4.336e-22	100.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
LZS1_k127_7334524_2	1283287.KB822577_gene3429	2.81e-13	73.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4DRU8@85009|Propionibacteriales	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
LZS1_k127_7334524_0	525904.Tter_1189	7.369e-118	390.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	citA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS1_k127_7334524_1	553217.ENHAE0001_0751	1.946e-17	89.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,3NRGK@468|Moraxellaceae	1236|Gammaproteobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
LZS1_k127_7346643_1	1379698.RBG1_1C00001G0655	1.154e-142	467.0	COG0380@1|root,COG0380@2|Bacteria,2NPDG@2323|unclassified Bacteria	2|Bacteria	G	Glycosyltransferase family 20	otsA	-	2.4.1.15,2.4.1.245,2.4.1.347,2.5.1.135	ko:K00697,ko:K13057,ko:K20436	ko00500,ko00525,ko01100,ko01130,map00500,map00525,map01100,map01130	M00815	R02737,R08946,R10525,R11239,R11250,R11306,R11497	RC00005,RC00049,RC02748,RC03400,RC03401	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT20,GT4	-	Glyco_transf_20
LZS1_k127_7346643_7	404589.Anae109_3831	3.889e-57	211.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,42YGA@68525|delta/epsilon subdivisions,2X9TU@28221|Deltaproteobacteria,2Z21Y@29|Myxococcales	28221|Deltaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS1_k127_7346643_0	309799.DICTH_1585	2.247e-159	514.0	COG0215@1|root,COG0215@2|Bacteria	2|Bacteria	J	cysteine-tRNA ligase activity	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
LZS1_k127_7346643_8	1552123.EP57_15835	1.889e-41	165.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,26J72@186820|Listeriaceae	91061|Bacilli	H	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
LZS1_k127_7346643_4	1489678.RDMS_12985	6.163e-71	256.0	COG1230@1|root,COG1230@2|Bacteria	2|Bacteria	P	cation diffusion facilitator family transporter	zitB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	iNRG857_1313.NRG857_03325,iPC815.YPO1129	Cation_efflux,ZT_dimer
LZS1_k127_7346643_5	401053.AciPR4_2230	1.126e-67	248.0	COG1524@1|root,COG1524@2|Bacteria,3Y4MJ@57723|Acidobacteria,2JNZ7@204432|Acidobacteriia	204432|Acidobacteriia	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS1_k127_7346643_12	1410620.SHLA_6c000420	2.628e-14	83.0	COG1564@1|root,COG1564@2|Bacteria,1REVK@1224|Proteobacteria,2U7U7@28211|Alphaproteobacteria,4B75E@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	thiamine pyrophosphokinase	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
LZS1_k127_7346643_3	483219.LILAB_26945	1.425e-78	286.0	COG4395@1|root,COG4395@2|Bacteria,1NKJZ@1224|Proteobacteria,43793@68525|delta/epsilon subdivisions,2X2CB@28221|Deltaproteobacteria,2YYKJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
LZS1_k127_7346643_2	357804.Ping_1307	8.806e-104	346.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,1S1VG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,HTH_17,SHOCT
LZS1_k127_7346643_11	525903.Taci_0155	1.856e-17	94.0	COG1409@1|root,COG1409@2|Bacteria,3TBDZ@508458|Synergistetes	508458|Synergistetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS1_k127_7346643_13	545695.TREAZ_2863	3.174e-10	74.0	COG1196@1|root,COG1196@2|Bacteria,2J663@203691|Spirochaetes	203691|Spirochaetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7346643_10	1009370.ALO_07313	4.713e-33	134.0	COG3216@1|root,COG3216@2|Bacteria	2|Bacteria	M	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
LZS1_k127_7346643_9	134676.ACPL_5550	1.052e-33	137.0	COG1974@1|root,COG1974@2|Bacteria,2I9XR@201174|Actinobacteria,4DIWD@85008|Micromonosporales	201174|Actinobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
LZS1_k127_7346643_14	760117.JN27_22375	3.653e-08	58.0	2DRVR@1|root,33DAW@2|Bacteria,1NJ5A@1224|Proteobacteria,2VXSF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
LZS1_k127_7346643_15	498848.TaqDRAFT_3668	6.17e-06	59.0	COG1547@1|root,COG1547@2|Bacteria,1WKCC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
LZS1_k127_7346643_6	439235.Dalk_1595	1.297e-63	232.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2MIJE@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM MltA	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
LZS1_k127_734705_0	290397.Adeh_4020	9.723e-60	213.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2WKK6@28221|Deltaproteobacteria,2YTTN@29|Myxococcales	28221|Deltaproteobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
LZS1_k127_734705_5	1237149.C900_03592	0.0004583	52.0	COG1247@1|root,COG1247@2|Bacteria,4NM05@976|Bacteroidetes,47YJJ@768503|Cytophagia	976|Bacteroidetes	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
LZS1_k127_734705_2	234267.Acid_5417	5.543e-46	184.0	COG0726@1|root,COG0726@2|Bacteria,3Y5MF@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS1_k127_734705_3	1123371.ATXH01000022_gene968	1.45e-43	165.0	COG0241@1|root,COG0241@2|Bacteria,2GHMG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Polynucleotide kinase 3 phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
LZS1_k127_734705_1	330214.NIDE1235	4.818e-52	193.0	COG0386@1|root,COG0386@2|Bacteria	2|Bacteria	O	Belongs to the glutathione peroxidase family	btuE	-	1.11.1.22,1.11.1.9	ko:K00432,ko:K20207	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	iJN678.slr1992	GSHPx
LZS1_k127_734705_4	56110.Oscil6304_3541	9.663e-23	109.0	COG1216@1|root,COG1216@2|Bacteria,1G09N@1117|Cyanobacteria,1H8HE@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glycos_transf_2
LZS1_k127_7362170_1	1396141.BATP01000060_gene4671	1.272e-25	107.0	COG1092@1|root,COG1092@2|Bacteria,46UWW@74201|Verrucomicrobia,2ITN4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA cap guanine-N2 methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
LZS1_k127_7362170_0	269482.Bcep1808_3639	2.283e-119	398.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2VRGQ@28216|Betaproteobacteria,1K6IJ@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS1_k127_7362170_3	404589.Anae109_0670	2.9e-06	55.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria,42PS3@68525|delta/epsilon subdivisions,2X7MQ@28221|Deltaproteobacteria,2YVCB@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_8
LZS1_k127_7362170_2	404589.Anae109_1681	9.561e-08	53.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria	1224|Proteobacteria	C	Aldo keto reductase	yghZ	GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	iSBO_1134.SBO_2995	Aldo_ket_red
LZS1_k127_7368763_8	867903.ThesuDRAFT_00219	1.768e-68	245.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3WD07@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS1_k127_7368763_4	1353529.M899_2052	3.076e-98	334.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,42QQ1@68525|delta/epsilon subdivisions,2MSYG@213481|Bdellovibrionales,2WMNS@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
LZS1_k127_7368763_6	1121878.AUGL01000010_gene951	1.413e-75	264.0	KOG0788@1|root,2Z9Q6@2|Bacteria,1R6QG@1224|Proteobacteria,1RYA8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM S-adenosylmethionine decarboxylase	speD	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	SAM_decarbox
LZS1_k127_7368763_12	32051.SynWH7803_2449	1.961e-24	119.0	COG1694@1|root,COG3956@2|Bacteria,1G151@1117|Cyanobacteria,1GYYW@1129|Synechococcus	1117|Cyanobacteria	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	iJN678.sll1005	MazG
LZS1_k127_7368763_3	626939.HMPREF9443_01498	6.995e-120	406.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H2SJ@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
LZS1_k127_7368763_0	1121428.DESHY_30001___1	3.009e-288	907.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,2601Z@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS1_k127_7368763_1	338963.Pcar_0004	3.928e-241	772.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
LZS1_k127_7368763_9	1121289.JHVL01000043_gene1081	1.157e-66	241.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,36E0C@31979|Clostridiaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
LZS1_k127_7368763_2	1267580.AF6_0001	5.437e-128	422.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,21V4X@150247|Anoxybacillus	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS1_k127_7368763_11	717231.Flexsi_0985	7.873e-27	116.0	COG1544@1|root,COG1544@2|Bacteria,2GFDP@200930|Deferribacteres	200930|Deferribacteres	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
LZS1_k127_7368763_5	1122917.KB899684_gene3187	1.17e-81	284.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,26QHT@186822|Paenibacillaceae	91061|Bacilli	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
LZS1_k127_7368763_7	404589.Anae109_0152	7.243e-73	268.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2YV1E@29|Myxococcales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
LZS1_k127_7368763_13	1265505.ATUG01000003_gene167	2.903e-20	98.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria,2MK4F@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
LZS1_k127_7368763_10	610130.Closa_0203	3.751e-27	122.0	COG3444@1|root,COG3444@2|Bacteria,1UXMU@1239|Firmicutes,25MHI@186801|Clostridia,2239Z@1506553|Lachnoclostridium	186801|Clostridia	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
LZS1_k127_7368763_14	404589.Anae109_0156	2.783e-07	61.0	COG3716@1|root,COG3716@2|Bacteria,1P02J@1224|Proteobacteria,42RPH@68525|delta/epsilon subdivisions,2WNQI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system mannose fructose sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
LZS1_k127_7396525_5	880073.Calab_2217	2.948e-16	94.0	COG2067@1|root,COG2067@2|Bacteria,2NRA4@2323|unclassified Bacteria	2|Bacteria	I	PFAM Uncharacterised protein family (UPF0164)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
LZS1_k127_7396525_6	1380390.JIAT01000014_gene6288	2.246e-10	75.0	COG0028@1|root,COG0515@1|root,COG1470@1|root,COG2133@1|root,COG3291@1|root,COG0028@2|Bacteria,COG0515@2|Bacteria,COG1470@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,PA14,PKD
LZS1_k127_7396525_7	1094466.KQS_02055	1.024e-05	60.0	COG3291@1|root,COG3405@1|root,COG3291@2|Bacteria,COG3405@2|Bacteria,4NMVW@976|Bacteroidetes,1I1JQ@117743|Flavobacteriia	976|Bacteroidetes	G	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
LZS1_k127_7396525_4	1128421.JAGA01000003_gene3000	6.474e-75	271.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974,ko:K07276,ko:K19545	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko01504,ko03016,ko03019	-	-	-	Aminoglyc_resit,HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
LZS1_k127_7396525_3	557599.MKAN_21580	1.079e-90	319.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,232HF@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS1_k127_7396525_2	374847.Kcr_1095	3.889e-103	344.0	COG1173@1|root,arCOG00748@2157|Archaea	2157|Archaea	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS1_k127_7396525_1	1150474.JQJI01000048_gene1239	1.175e-104	349.0	COG0601@1|root,COG0601@2|Bacteria,2GBX3@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS1_k127_7396525_0	374847.Kcr_1093	1.408e-111	372.0	COG0747@1|root,arCOG01534@2157|Archaea	2157|Archaea	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS1_k127_7397978_2	1210884.HG799468_gene13832	8.681e-95	321.0	COG0046@1|root,COG0046@2|Bacteria,2IXRT@203682|Planctomycetes	203682|Planctomycetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
LZS1_k127_7397978_3	765420.OSCT_0338	4.516e-77	274.0	COG0047@1|root,COG0047@2|Bacteria,2G6R9@200795|Chloroflexi,374TW@32061|Chloroflexia	32061|Chloroflexia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
LZS1_k127_7397978_6	448385.sce1520	5.117e-07	56.0	COG1544@1|root,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
LZS1_k127_7397978_0	404589.Anae109_4136	4.359e-181	594.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2Z33Y@29|Myxococcales	28221|Deltaproteobacteria	M	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
LZS1_k127_7397978_5	863365.XHC_3529	7.523e-11	75.0	COG2199@1|root,COG3292@1|root,COG2199@2|Bacteria,COG3292@2|Bacteria,1RGCV@1224|Proteobacteria,1T227@1236|Gammaproteobacteria,1XD7F@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
LZS1_k127_7397978_1	1144275.COCOR_01049	6.144e-156	504.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2YTTF@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
LZS1_k127_7397978_4	768670.Calni_0857	2.535e-62	241.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,DEAD,DUF4384,Helicase_C,Peptidase_C14,Polysacc_deac_1,TPR_11,TPR_16,TPR_2,TPR_8,WD40
LZS1_k127_741515_3	269797.Mbar_A1826	1.8e-07	63.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota,2NARR@224756|Methanomicrobia	224756|Methanomicrobia	T	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
LZS1_k127_741515_2	1179773.BN6_37030	8.983e-15	84.0	COG0121@1|root,COG0121@2|Bacteria,2GJSY@201174|Actinobacteria,4E8FB@85010|Pseudonocardiales	201174|Actinobacteria	S	Glutamine amidotransferases class-II	-	-	3.5.1.118	ko:K07008	ko00340,map00340	-	R11021	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	GATase_4
LZS1_k127_741515_1	693661.Arcve_1277	8.061e-15	87.0	COG4747@1|root,arCOG04444@2157|Archaea,2XXTI@28890|Euryarchaeota,24737@183980|Archaeoglobi	183980|Archaeoglobi	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
LZS1_k127_741515_0	765869.BDW_03840	3.602e-34	141.0	2FIK9@1|root,34ACA@2|Bacteria,1P27B@1224|Proteobacteria,4314P@68525|delta/epsilon subdivisions,2MT83@213481|Bdellovibrionales,2WX2C@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7448695_0	436229.JOEH01000011_gene5406	0.0003618	51.0	COG4427@1|root,COG4427@2|Bacteria,2HVQW@201174|Actinobacteria,2NEEE@228398|Streptacidiphilus	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
LZS1_k127_7451760_0	1033810.HLPCO_002978	1.09e-49	184.0	COG0469@1|root,COG0469@2|Bacteria,2NNKX@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the pyruvate kinase family	pyk	GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065	2.7.1.40,2.7.7.4	ko:K00873,ko:K00958	ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050,M00176,M00596	R00200,R00430,R00529,R01138,R01858,R02320,R04929	RC00002,RC00015,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iECO103_1326.ECO103_1819,iPC815.YPO2393	PEP-utilizers,PK,PK_C
LZS1_k127_7451760_3	869210.Marky_1021	1.001e-29	121.0	COG1324@1|root,COG1324@2|Bacteria,1WKG6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
LZS1_k127_7451760_4	521011.Mpal_1003	2.115e-20	101.0	COG1018@1|root,arCOG02200@2157|Archaea,2XVD3@28890|Euryarchaeota,2N9JH@224756|Methanomicrobia	224756|Methanomicrobia	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
LZS1_k127_7451760_1	861450.HMPREF0080_00974	8.353e-35	141.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,4H4NK@909932|Negativicutes	909932|Negativicutes	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
LZS1_k127_7451760_2	526227.Mesil_1067	8.042e-31	139.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1WM1I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS1_k127_7528425_3	56110.Oscil6304_2890	1.542e-23	106.0	COG2402@1|root,COG2402@2|Bacteria,1G5QP@1117|Cyanobacteria,1HF6X@1150|Oscillatoriales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
LZS1_k127_7528425_5	483219.LILAB_01755	4.738e-10	71.0	COG1413@1|root,COG1413@2|Bacteria,1NR1B@1224|Proteobacteria,42YUS@68525|delta/epsilon subdivisions,2WUMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
LZS1_k127_7528425_4	78398.KS43_17725	1.258e-16	84.0	COG3636@1|root,COG3636@2|Bacteria,1N1JW@1224|Proteobacteria,1S97N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7528425_2	1218352.B597_017845	1.885e-29	120.0	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,1SCNC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
LZS1_k127_7528425_1	879310.HMPREF9162_0078	2.707e-32	133.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,4H3NM@909932|Negativicutes	909932|Negativicutes	I	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
LZS1_k127_7528425_0	1183438.GKIL_2224	2.553e-123	408.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2,Peptidase_M3
LZS1_k127_7529992_0	926560.KE387025_gene4070	7.554e-72	250.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K07100	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
LZS1_k127_7529992_2	1123057.P872_09795	1.06e-12	80.0	COG2230@1|root,COG2230@2|Bacteria,4NHFT@976|Bacteroidetes,47MHX@768503|Cytophagia	976|Bacteroidetes	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS1_k127_7529992_1	296591.Bpro_3451	3.467e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,1NDUF@1224|Proteobacteria,2VXMY@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS1_k127_7568559_7	1511.CLOST_2161	4.985e-20	94.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,25RE4@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS1_k127_7568559_6	944479.JQLX01000016_gene329	8.272e-37	148.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2M772@213113|Desulfurellales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
LZS1_k127_7568559_0	360107.CHAB381_1552	3.46e-85	287.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,42MV8@68525|delta/epsilon subdivisions,2YMAE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
LZS1_k127_7568559_3	391625.PPSIR1_11225	3.033e-57	218.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria	1224|Proteobacteria	H	squalene-associated FAD-dependent desaturase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
LZS1_k127_7568559_2	1454004.AW11_01907	2.146e-59	216.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,1KQE3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
LZS1_k127_7568559_1	391625.PPSIR1_11190	9.04e-76	280.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria	1224|Proteobacteria	I	PFAM Squalene phytoene synthase	hpnC	-	2.5.1.103,2.5.1.32,2.5.1.99,4.2.3.156	ko:K02291,ko:K21678,ko:K21679	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
LZS1_k127_7568559_5	383372.Rcas_4265	1.086e-52	195.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi,3752E@32061|Chloroflexia	32061|Chloroflexia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
LZS1_k127_7568559_4	644966.Tmar_2202	5.695e-56	201.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3WCE5@538999|Clostridiales incertae sedis	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
LZS1_k127_7569661_0	997346.HMPREF9374_0644	3.527e-127	446.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,27B3G@186824|Thermoactinomycetaceae	91061|Bacilli	E	Cys/Met metabolism PLP-dependent enzyme	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_7569661_6	903818.KI912268_gene3184	0.0004973	50.0	COG0640@1|root,COG0640@2|Bacteria,3Y5UV@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
LZS1_k127_7569661_1	682795.AciX8_4283	1.96e-98	337.0	COG1063@1|root,COG1063@2|Bacteria,3Y3KU@57723|Acidobacteria,2JIQ4@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS1_k127_7569661_2	1382356.JQMP01000001_gene1011	2.193e-65	233.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi,27XF7@189775|Thermomicrobia	189775|Thermomicrobia	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
LZS1_k127_7569661_3	1284352.AOIG01000007_gene2164	1.31e-33	133.0	COG2363@1|root,COG2363@2|Bacteria,1VA79@1239|Firmicutes,4HKHG@91061|Bacilli,26Z1H@186822|Paenibacillaceae	91061|Bacilli	S	membrane	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
LZS1_k127_7569661_5	1313265.JNIE01000003_gene1133	2.674e-06	58.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
LZS1_k127_7598_0	880073.Calab_1153	6.4e-97	333.0	COG0591@1|root,COG0591@2|Bacteria,2NRJT@2323|unclassified Bacteria	2|Bacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS1_k127_7598_3	1123253.AUBD01000002_gene1420	3.394e-06	61.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SZJ7@1236|Gammaproteobacteria,1X76A@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
LZS1_k127_7598_4	1121946.AUAX01000018_gene6962	2.344e-05	58.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DB4F@85008|Micromonosporales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
LZS1_k127_7598_2	381764.Fnod_1043	3.185e-51	190.0	COG0730@1|root,COG0730@2|Bacteria,2GDU8@200918|Thermotogae	200918|Thermotogae	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS1_k127_7598_1	521674.Plim_1373	7.509e-56	203.0	COG0662@1|root,COG1850@1|root,COG0662@2|Bacteria,COG1850@2|Bacteria	2|Bacteria	G	ribulose-bisphosphate carboxylase activity	mtnW	-	4.1.1.39	ko:K01601,ko:K21700	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,RuBisCO_large
LZS1_k127_7600641_3	765869.BDW_09605	3.258e-48	185.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
LZS1_k127_7600641_2	1123020.AUIE01000019_gene2874	1.54e-48	184.0	2B7YH@1|root,3215N@2|Bacteria,1RJP9@1224|Proteobacteria,1S6AA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
LZS1_k127_7600641_1	321332.CYB_2529	2.223e-221	707.0	COG0296@1|root,COG0296@2|Bacteria,1G0N3@1117|Cyanobacteria,1GZZS@1129|Synechococcus	1117|Cyanobacteria	G	4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase	treZ	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
LZS1_k127_7600641_0	909663.KI867151_gene3005	2.159e-221	711.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,42MEW@68525|delta/epsilon subdivisions,2WJX1@28221|Deltaproteobacteria,2MQXA@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM alpha amylase, catalytic	treY	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
LZS1_k127_7645184_0	1125863.JAFN01000001_gene534	9.425e-70	255.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS1_k127_7645184_1	378806.STAUR_7219	1.688e-54	210.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2WIUX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
LZS1_k127_7645184_2	378806.STAUR_7221	1.288e-23	106.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1PFJ3@1224|Proteobacteria,439XK@68525|delta/epsilon subdivisions,2X2ER@28221|Deltaproteobacteria,2Z1AS@29|Myxococcales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_7662270_0	1120973.AQXL01000131_gene2130	1.684e-53	213.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS1_k127_7747134_0	1125863.JAFN01000001_gene2044	1.994e-151	494.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
LZS1_k127_7747134_6	926569.ANT_16910	6.852e-09	67.0	COG1508@1|root,COG1508@2|Bacteria,2G5VM@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
LZS1_k127_7747134_2	1174504.AJTN02000241_gene4338	7.505e-49	192.0	COG4191@1|root,COG4191@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,PAS_9
LZS1_k127_7747134_1	290397.Adeh_0417	1.634e-123	417.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YX5F@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	nla19	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS1_k127_7747134_4	1380394.JADL01000005_gene5355	1.079e-13	78.0	COG0784@1|root,COG0784@2|Bacteria,1NHP4@1224|Proteobacteria,2UWGS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS1_k127_7747134_3	1227457.C451_04231	2.087e-14	83.0	COG0589@1|root,arCOG00449@2157|Archaea,2XVPB@28890|Euryarchaeota,23SHQ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS1_k127_7747134_5	1379698.RBG1_1C00001G0853	1.287e-12	76.0	290MS@1|root,2ZNA5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7751136_5	880073.Calab_2684	4.91e-58	207.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
LZS1_k127_7751136_1	880073.Calab_2685	2.026e-123	422.0	COG1009@1|root,COG1009@2|Bacteria,2NNM8@2323|unclassified Bacteria	2|Bacteria	CP	NADH-quinone oxidoreductase chain L	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
LZS1_k127_7751136_9	765420.OSCT_2925	2.916e-25	115.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi,375VH@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
LZS1_k127_7751136_11	316274.Haur_4986	1.413e-20	101.0	COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi,375K1@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
LZS1_k127_7751136_10	1379698.RBG1_1C00001G1875	4.69e-21	101.0	COG1143@1|root,COG1143@2|Bacteria,2NPQR@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00337,ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
LZS1_k127_7751136_2	880073.Calab_2689	2.469e-84	300.0	COG1005@1|root,COG1005@2|Bacteria,2NQIK@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00337,ko:K05572	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS1_k127_7751136_0	1280390.CBQR020000150_gene3966	1.121e-125	413.0	COG0649@1|root,COG0649@2|Bacteria,1TQAR@1239|Firmicutes,4HA4Y@91061|Bacilli,26T7E@186822|Paenibacillaceae	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
LZS1_k127_7751136_12	649349.Lbys_0643	1.826e-19	96.0	COG0852@1|root,COG0852@2|Bacteria,4NPGA@976|Bacteroidetes,47PNZ@768503|Cytophagia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
LZS1_k127_7751136_4	867903.ThesuDRAFT_02259	2.489e-59	210.0	COG0377@1|root,COG0377@2|Bacteria,1TZS1@1239|Firmicutes,24GH5@186801|Clostridia	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
LZS1_k127_7751136_8	1162668.LFE_1700	1.227e-26	124.0	COG0838@1|root,COG0838@2|Bacteria,3J0MS@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
LZS1_k127_7751136_7	1120973.AQXL01000110_gene1002	2.814e-47	184.0	COG1565@1|root,COG1565@2|Bacteria,1V2II@1239|Firmicutes,4HHGV@91061|Bacilli,278C9@186823|Alicyclobacillaceae	91061|Bacilli	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
LZS1_k127_7751136_13	264462.Bd0055	0.0004631	45.0	COG2036@1|root,33IMA@2|Bacteria,1Q233@1224|Proteobacteria,437QD@68525|delta/epsilon subdivisions,2MUDJ@213481|Bdellovibrionales,2X2YX@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	protein heterodimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	CBFD_NFYB_HMF
LZS1_k127_7751136_6	1382306.JNIM01000001_gene3830	3.493e-48	182.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS1_k127_7751136_3	517418.Ctha_0236	8.897e-62	235.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS1_k127_7760357_9	264462.Bd2088	5.155e-05	48.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,1QY1R@1224|Proteobacteria,43C93@68525|delta/epsilon subdivisions,2MUT2@213481|Bdellovibrionales,2X7JI@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	cell wall surface anchor family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
LZS1_k127_7760357_2	690850.Desaf_0959	6.108e-113	378.0	COG2327@1|root,COG2327@2|Bacteria,1R9R8@1224|Proteobacteria,42U55@68525|delta/epsilon subdivisions,2WQGP@28221|Deltaproteobacteria,2MDZ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
LZS1_k127_7760357_7	751994.AGIG01000017_gene87	1.59e-31	139.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,HemolysinCabind
LZS1_k127_7760357_5	1123366.TH3_14749	8.877e-47	195.0	COG0457@1|root,COG0457@2|Bacteria,1N1I4@1224|Proteobacteria,2V9ES@28211|Alphaproteobacteria,2JTPA@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_19
LZS1_k127_7760357_1	1238182.C882_3869	2.56e-190	618.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,2JQU2@204441|Rhodospirillales	204441|Rhodospirillales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
LZS1_k127_7760357_3	469383.Cwoe_2865	1.129e-88	302.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
LZS1_k127_7760357_0	237368.SCABRO_01197	3.631e-226	710.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
LZS1_k127_7760357_8	366649.XFF4834R_chr21900	4.352e-14	87.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1X47B@135614|Xanthomonadales	135614|Xanthomonadales	S	DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
LZS1_k127_7760357_4	760568.Desku_1925	1.929e-56	208.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,260CC@186807|Peptococcaceae	186801|Clostridia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
LZS1_k127_7760357_6	887898.HMPREF0551_0397	4.508e-32	130.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,1K174@119060|Burkholderiaceae	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
LZS1_k127_7765547_0	589924.Ferp_0317	0.0	1226.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota,245PG@183980|Archaeoglobi	183980|Archaeoglobi	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
LZS1_k127_7765547_5	368407.Memar_1158	3.11e-23	105.0	COG0642@1|root,arCOG06536@1|root,arCOG06192@2157|Archaea,arCOG06536@2157|Archaea	2157|Archaea	T	PAS domain	-	-	2.7.7.72	ko:K00974,ko:K02485	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko02022,ko03016	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS1_k127_7765547_6	264462.Bd2432	1.29e-21	102.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,42W41@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
LZS1_k127_7765547_4	526227.Mesil_2000	8.687e-37	143.0	COG0735@1|root,COG0735@2|Bacteria,1WJYT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS1_k127_7765547_7	638303.Thal_1089	2.605e-19	100.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7765547_2	247490.KSU1_D0783	8.625e-54	202.0	COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes	203682|Planctomycetes	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
LZS1_k127_7765547_3	404589.Anae109_1536	1.477e-46	176.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
LZS1_k127_7765547_1	247490.KSU1_D0785	1.207e-68	253.0	COG1108@1|root,COG1108@2|Bacteria	2|Bacteria	P	ABC-type Mn2 Zn2 transport systems permease components	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
LZS1_k127_7765547_8	1090320.KB900605_gene3655	9.855e-06	57.0	COG0428@1|root,COG0428@2|Bacteria,1Q7FM@1224|Proteobacteria,2VDKU@28211|Alphaproteobacteria,2K5HG@204457|Sphingomonadales	204457|Sphingomonadales	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
LZS1_k127_7768759_0	1463901.JOIY01000030_gene268	1.879e-28	131.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
LZS1_k127_7768759_1	357808.RoseRS_0687	4.222e-26	127.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria,2G9QS@200795|Chloroflexi	200795|Chloroflexi	T	SMART RNA-processing protein HAT helix repeating-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,TPR_16,TPR_19,TPR_8
LZS1_k127_7768759_2	1121346.KB899813_gene2194	1.033e-19	105.0	COG4244@1|root,COG4244@2|Bacteria,1UHFB@1239|Firmicutes,4HCQT@91061|Bacilli,26UEU@186822|Paenibacillaceae	91061|Bacilli	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7768759_3	1218074.BAXZ01000020_gene3928	2.332e-08	67.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2VP95@28216|Betaproteobacteria,1K3PP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_1,TPR_16,TPR_2,TPR_8
LZS1_k127_7779682_3	1232410.KI421421_gene3462	6.841e-32	128.0	COG1850@1|root,COG1917@1|root,COG1850@2|Bacteria,COG1917@2|Bacteria,1MWEB@1224|Proteobacteria	1224|Proteobacteria	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	mtnW	-	4.1.1.39,5.3.2.5	ko:K01601,ko:K08965	ko00270,ko00630,ko00710,ko01100,ko01120,ko01200,map00270,map00630,map00710,map01100,map01120,map01200	M00034,M00165,M00166,M00532	R00024,R03140,R07393	RC00172,RC00859,RC02421	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large
LZS1_k127_7779682_12	1123255.JHYS01000006_gene274	1.337e-09	72.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,4ABTM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS1_k127_7779682_5	1173027.Mic7113_2574	1.678e-18	101.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G2R4@1117|Cyanobacteria,1H8BH@1150|Oscillatoriales	1117|Cyanobacteria	CT	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
LZS1_k127_7779682_9	671143.DAMO_2268	1.913e-11	69.0	COG4679@1|root,COG4679@2|Bacteria	2|Bacteria	K	PFAM Phage derived protein Gp49-like (DUF891)	-	GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0045926,GO:0045927,GO:0046483,GO:0048518,GO:0048519,GO:0050789,GO:0050896,GO:0065007,GO:0070482,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	Gp49
LZS1_k127_7779682_6	671143.DAMO_2267	3.378e-14	76.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	cI	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,Peptidase_S24
LZS1_k127_7779682_8	251221.35212131	1.026e-12	77.0	2AVYW@1|root,31MT4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7779682_10	272123.Anacy_3661	2.801e-11	67.0	2E33J@1|root,32Y3P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7779682_7	944481.JAFP01000001_gene96	5.289e-13	74.0	COG4190@1|root,COG4190@2|Bacteria,1Q116@1224|Proteobacteria,4371C@68525|delta/epsilon subdivisions,2WYD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_7779682_2	1238182.C882_1246	5.118e-44	167.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,2JRWF@204441|Rhodospirillales	204441|Rhodospirillales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
LZS1_k127_7779682_11	888439.HMPREF9240_00191	8.966e-10	61.0	COG0291@1|root,COG0291@2|Bacteria,2GQZW@201174|Actinobacteria,4D6F8@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
LZS1_k127_7779682_4	861530.ALOZ01000056_gene1502	2.963e-30	123.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,4GZ42@90964|Staphylococcaceae	91061|Bacilli	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
LZS1_k127_7779682_1	649747.HMPREF0083_02303	1.942e-107	360.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli,26RWY@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
LZS1_k127_7779682_0	1345697.M493_14015	2.557e-157	524.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,1WFCH@129337|Geobacillus	91061|Bacilli	J	Ferredoxin-fold anticodon binding domain	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
LZS1_k127_7781344_4	644966.Tmar_1587	1.821e-17	89.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3WDS9@538999|Clostridiales incertae sedis	186801|Clostridia	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_7781344_2	330214.NIDE3821	2.603e-71	252.0	COG0836@1|root,COG0836@2|Bacteria	2|Bacteria	M	mannose-1-phosphate guanylyltransferase activity	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
LZS1_k127_7781344_0	880073.Calab_2583	1.327e-122	406.0	COG2230@1|root,COG2230@2|Bacteria,2NQ94@2323|unclassified Bacteria	2|Bacteria	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS1_k127_7781344_1	1288494.EBAPG3_24560	1.711e-93	320.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,372TF@32003|Nitrosomonadales	28216|Betaproteobacteria	KT	PFAM Metal-dependent phosphohydrolase, HD	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,GAF_2,HD
LZS1_k127_7781344_3	1210884.HG799464_gene10872	7.89e-67	246.0	COG2047@1|root,COG2047@2|Bacteria	2|Bacteria	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
LZS1_k127_7783445_0	1121943.KB899994_gene1033	1.277e-09	61.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,1S3QR@1236|Gammaproteobacteria,1XJUJ@135619|Oceanospirillales	135619|Oceanospirillales	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
LZS1_k127_7806201_6	236814.IX39_06275	3.158e-06	55.0	COG1572@1|root,COG1572@2|Bacteria,4NDY7@976|Bacteroidetes,1HYJD@117743|Flavobacteriia,3ZQZK@59732|Chryseobacterium	976|Bacteroidetes	S	Peptidase family C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
LZS1_k127_7806201_1	269799.Gmet_2694	1.604e-45	188.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Phosphate sensor histidine kinase, HAMP and PAS domain-containing	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS1_k127_7806201_4	290317.Cpha266_1484	4.333e-26	120.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
LZS1_k127_7806201_0	1047013.AQSP01000142_gene165	6.236e-228	726.0	COG3591@1|root,COG3591@2|Bacteria,2NQEJ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
LZS1_k127_7806201_2	309807.SRU_0527	3.303e-44	183.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,1FIYA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
LZS1_k127_7806201_5	1122138.AQUZ01000010_gene5118	7.777e-14	84.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,4DSTE@85009|Propionibacteriales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DUF1100,Peptidase_S9
LZS1_k127_7806201_3	314345.SPV1_05258	3.04e-26	124.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria	1224|Proteobacteria	M	lytic murein transglycosylase	mltB	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031402,GO:0031420,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0044462,GO:0044464,GO:0046872,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	iECABU_c1320.ECABU_c29710,iNRG857_1313.NRG857_13215	SLT_2
LZS1_k127_7812599_1	743299.Acife_1303	2.111e-24	108.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,2NC9P@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
LZS1_k127_7812599_0	1123371.ATXH01000012_gene1415	1.015e-183	592.0	COG0442@1|root,COG0442@2|Bacteria,2GH47@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
LZS1_k127_7812599_2	1304880.JAGB01000001_gene230	1.959e-15	78.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
LZS1_k127_7824376_0	1283300.ATXB01000001_gene1800	4.934e-171	548.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1XDMT@135618|Methylococcales	1236|Gammaproteobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS1_k127_7824376_3	1307761.L21SP2_2827	1.62e-14	80.0	COG1734@1|root,COG1734@2|Bacteria,2J7Y1@203691|Spirochaetes	203691|Spirochaetes	T	Prokaryotic dksA traR C4-type zinc finger	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
LZS1_k127_7824376_1	429009.Adeg_0526	6.564e-137	454.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
LZS1_k127_7824376_2	330214.NIDE1583	3.641e-99	344.0	COG0497@1|root,COG0497@2|Bacteria,3J0HU@40117|Nitrospirae	40117|Nitrospirae	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
LZS1_k127_7824376_4	269799.Gmet_0941	1.592e-10	63.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
LZS1_k127_7869654_2	1313304.CALK_0381	3.309e-29	125.0	COG0565@1|root,COG0565@2|Bacteria	2|Bacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
LZS1_k127_7869654_0	926550.CLDAP_22130	1.268e-59	211.0	COG1051@1|root,COG1051@2|Bacteria,2G7HA@200795|Chloroflexi	200795|Chloroflexi	F	PFAM NUDIX hydrolase	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS1_k127_7869654_3	404589.Anae109_0678	1.166e-15	87.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2Z31A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
LZS1_k127_7869654_1	756272.Plabr_1573	1.733e-57	209.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_7906247_4	1157640.AQWO01000014_gene1264	3.652e-05	56.0	COG0793@1|root,COG0793@2|Bacteria,2GKRP@201174|Actinobacteria	201174|Actinobacteria	M	Peptidase, S41	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS1_k127_7906247_1	1345697.M493_18200	1.815e-78	285.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,4HA91@91061|Bacilli,1WEN2@129337|Geobacillus	91061|Bacilli	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
LZS1_k127_7906247_0	525904.Tter_0805	9.607e-162	520.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS1_k127_7906247_2	1210884.HG799464_gene10997	1.609e-11	71.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
LZS1_k127_7908146_0	1157637.KB892110_gene4258	1.432e-22	112.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
LZS1_k127_7908146_1	1530186.JQEY01000008_gene3022	1.3e-18	91.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_7910110_1	1266925.JHVX01000001_gene2483	1.736e-86	300.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2WAY9@28216|Betaproteobacteria,371NX@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
LZS1_k127_7910110_4	1123368.AUIS01000032_gene1389	1.978e-16	81.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
LZS1_k127_7910110_3	1476583.DEIPH_ctg139orf0014	3.66e-40	156.0	COG0517@1|root,COG0517@2|Bacteria,1WNHR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS1_k127_7910110_0	1232410.KI421428_gene1038	3.558e-163	526.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43T9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
LZS1_k127_7910110_2	670307.HYPDE_33213	3.543e-77	271.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria	1224|Proteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
LZS1_k127_7911583_2	591001.Acfer_1829	2.526e-37	148.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4H2DZ@909932|Negativicutes	909932|Negativicutes	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
LZS1_k127_7911583_1	243164.DET0620	4.45e-50	192.0	COG2887@1|root,COG2887@2|Bacteria,2GBU9@200795|Chloroflexi,34CT2@301297|Dehalococcoidia	301297|Dehalococcoidia	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
LZS1_k127_7911583_0	1536769.P40081_23900	3.607e-82	294.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,26QJT@186822|Paenibacillaceae	91061|Bacilli	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
LZS1_k127_7926897_6	290397.Adeh_3773	1.046e-10	63.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2WN8T@28221|Deltaproteobacteria,2Z308@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
LZS1_k127_7926897_2	316067.Geob_0785	2.885e-77	274.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
LZS1_k127_7926897_0	264732.Moth_0850	3.815e-98	342.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,42EUU@68295|Thermoanaerobacterales	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS1_k127_7926897_1	319795.Dgeo_0256	5.019e-95	341.0	COG2805@1|root,COG2805@2|Bacteria,1WI5S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Tfp pilus assembly protein pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS1_k127_7926897_3	5741.EDO80901	1.29e-37	154.0	COG1428@1|root,KOG3877@2759|Eukaryota	2759|Eukaryota	F	mitochondrial electron transport, NADH to ubiquinone	-	-	2.7.1.76	ko:K10353	ko00230,ko01100,map00230,map01100	-	R02089	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	dNK
LZS1_k127_7926897_5	1071679.BG57_15475	1.597e-20	100.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,1K3K8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
LZS1_k127_7926897_4	637389.Acaty_c1155	6.955e-26	113.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,2NCCE@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_7947252_0	765420.OSCT_0508	6.452e-165	533.0	COG1960@1|root,COG1960@2|Bacteria,2G7Q9@200795|Chloroflexi,37704@32061|Chloroflexia	32061|Chloroflexia	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS1_k127_7947252_1	379731.PST_2275	1.364e-37	149.0	COG4273@1|root,COG4273@2|Bacteria,1MZN7@1224|Proteobacteria,1SRY2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF2703)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2703
LZS1_k127_7947252_2	2045.KR76_23670	0.0008582	48.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4DNTM@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_7972943_7	880073.Calab_2958	0.0001966	52.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,Invasin_D3,SLH
LZS1_k127_7972943_5	448385.sce2756	4.766e-15	86.0	COG1413@1|root,COG1413@2|Bacteria,1RK8P@1224|Proteobacteria,42VXW@68525|delta/epsilon subdivisions,2WRH4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
LZS1_k127_7972943_3	330214.NIDE1116	1.112e-83	303.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,3J0XC@40117|Nitrospirae	40117|Nitrospirae	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
LZS1_k127_7972943_6	592029.DDD_3255	6.419e-06	57.0	COG5061@1|root,COG5061@2|Bacteria,4NJWC@976|Bacteroidetes,1HXKF@117743|Flavobacteriia,3HJKB@363408|Nonlabens	976|Bacteroidetes	OU	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
LZS1_k127_7972943_2	1123253.AUBD01000008_gene522	9.635e-131	428.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1X3A8@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS1_k127_7972943_1	1267533.KB906737_gene1703	3.496e-141	466.0	COG2986@1|root,COG2986@2|Bacteria,3Y3YW@57723|Acidobacteria,2JIK6@204432|Acidobacteriia	204432|Acidobacteriia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
LZS1_k127_7972943_0	204669.Acid345_1048	8.207e-254	792.0	COG2987@1|root,COG2987@2|Bacteria,3Y2VD@57723|Acidobacteria,2JK4Z@204432|Acidobacteriia	204432|Acidobacteriia	E	Urocanase Rossmann-like domain	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
LZS1_k127_7972943_4	1121346.KB899818_gene2556	7.601e-37	145.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,26WQF@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0234 family	yitK	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
LZS1_k127_8002099_0	1121920.AUAU01000023_gene2396	9.974e-149	486.0	COG0773@1|root,COG1376@1|root,COG0773@2|Bacteria,COG1376@2|Bacteria,3Y304@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the MurCDEF family	-	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M,YkuD
LZS1_k127_8002099_1	909663.KI867150_gene688	6.201e-06	51.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	ydhO	-	3.4.14.13	ko:K20742,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SLH
LZS1_k127_8003445_4	62928.azo3245	0.0001006	54.0	COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria,2VMF9@28216|Betaproteobacteria,2KVT0@206389|Rhodocyclales	206389|Rhodocyclales	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_8003445_1	1457393.AZ09_09725	5.958e-51	195.0	COG0542@1|root,COG0542@2|Bacteria,1R445@1224|Proteobacteria,2U46G@28211|Alphaproteobacteria,2JZP9@204441|Rhodospirillales	204441|Rhodospirillales	O	Torsin	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2
LZS1_k127_8003445_0	1408473.JHXO01000002_gene3933	1.919e-74	259.0	COG0670@1|root,COG0670@2|Bacteria,4NG98@976|Bacteroidetes,2FQXN@200643|Bacteroidia	976|Bacteroidetes	S	Belongs to the BI1 family	ybhL	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
LZS1_k127_8003445_2	1179773.BN6_18660	1.948e-26	126.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4DYIP@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS1_k127_8003445_3	680198.SCAB_10851	3.467e-08	60.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_8030637_1	525903.Taci_0282	3.362e-55	222.0	COG1807@1|root,COG1807@2|Bacteria,3TAR6@508458|Synergistetes	508458|Synergistetes	M	PFAM glycosyl transferase family 39	-	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	PMT_2
LZS1_k127_8030637_0	391625.PPSIR1_13615	3.271e-90	307.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS1_k127_8030637_3	518766.Rmar_0357	9.843e-17	96.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
LZS1_k127_8030637_4	40571.JOEA01000012_gene1059	6.466e-05	57.0	COG1881@1|root,COG2133@1|root,COG1881@2|Bacteria,COG2133@2|Bacteria,2GISM@201174|Actinobacteria,4E1H5@85010|Pseudonocardiales	201174|Actinobacteria	G	Carbohydrate binding module (family 35)	-	-	-	-	-	-	-	-	-	-	-	-	CBM_35,CBM_6,GSDH,PBP,fn3
LZS1_k127_8030637_2	1268622.AVS7_03093	9.174e-49	201.0	COG3055@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4447@2|Bacteria,1MYQG@1224|Proteobacteria,2VX2F@28216|Betaproteobacteria,4AI7B@80864|Comamonadaceae	28216|Betaproteobacteria	S	by MetaGeneAnnotator	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_4,fn3
LZS1_k127_8046532_5	84531.JMTZ01000096_gene718	1.121e-45	179.0	COG0642@1|root,COG2205@2|Bacteria,1QVS7@1224|Proteobacteria,1T2IP@1236|Gammaproteobacteria,1X68Y@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS1_k127_8046532_1	1192034.CAP_6198	3.048e-87	321.0	COG2234@1|root,COG2234@2|Bacteria,1MXJC@1224|Proteobacteria,42RKA@68525|delta/epsilon subdivisions,2WUCM@28221|Deltaproteobacteria,2YWU8@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
LZS1_k127_8046532_6	378806.STAUR_1528	8.04e-26	117.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
LZS1_k127_8046532_4	517418.Ctha_0519	6.759e-51	188.0	COG0637@1|root,COG0637@2|Bacteria,1FE29@1090|Chlorobi	1090|Chlorobi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS1_k127_8046532_0	330214.NIDE3111	5.477e-94	319.0	COG0179@1|root,COG0179@2|Bacteria,3J1AP@40117|Nitrospirae	40117|Nitrospirae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
LZS1_k127_8046532_2	1303518.CCALI_02445	1.94e-77	276.0	COG3508@1|root,COG3508@2|Bacteria	2|Bacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
LZS1_k127_8046532_3	1111479.AXAR01000001_gene333	8.591e-57	210.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,279PY@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
LZS1_k127_8046999_3	1128421.JAGA01000002_gene1545	1.161e-43	179.0	COG0617@1|root,COG0617@2|Bacteria	2|Bacteria	J	CTP:tRNA cytidylyltransferase activity	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd
LZS1_k127_8046999_1	203119.Cthe_0686	6.81e-108	362.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS1_k127_8046999_2	316067.Geob_3015	9.862e-46	175.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
LZS1_k127_8046999_4	1449126.JQKL01000010_gene416	1.55e-39	162.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,269DT@186813|unclassified Clostridiales	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
LZS1_k127_8046999_0	1232410.KI421412_gene319	9.392e-129	428.0	COG0297@1|root,COG0366@1|root,COG0297@2|Bacteria,COG0366@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,43U7I@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Starch synthase catalytic domain	glgA-2	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Alpha-amylase,Glyco_transf_5,Glycos_transf_1
LZS1_k127_8053380_3	481448.Minf_1965	0.0001584	55.0	29E6W@1|root,3014W@2|Bacteria,46Z0K@74201|Verrucomicrobia,37GZ4@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_8053380_0	429009.Adeg_1440	1.641e-201	657.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,42EUK@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS1_k127_8053380_1	190650.CC_0038	4.798e-50	186.0	COG0412@1|root,COG0412@2|Bacteria,1PSEB@1224|Proteobacteria,2TTN4@28211|Alphaproteobacteria,2KI39@204458|Caulobacterales	204458|Caulobacterales	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
LZS1_k127_8053380_2	240015.ACP_1839	2.035e-46	174.0	COG2081@1|root,COG2081@2|Bacteria,3Y3KG@57723|Acidobacteria,2JHPT@204432|Acidobacteriia	204432|Acidobacteriia	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
LZS1_k127_8081812_1	864069.MicloDRAFT_00014520	0.0001219	48.0	COG1522@1|root,COG1522@2|Bacteria,1MZ9D@1224|Proteobacteria,2U7BV@28211|Alphaproteobacteria,1JV62@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
LZS1_k127_8081812_0	566461.SSFG_02212	1.705e-120	414.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS1_k127_8083466_3	1340493.JNIF01000003_gene1463	1.064e-32	135.0	2CH0S@1|root,341IR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_8083466_0	96561.Dole_2898	2.548e-59	227.0	COG0666@1|root,COG4249@1|root,COG0666@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,42VKX@68525|delta/epsilon subdivisions,2WSQB@28221|Deltaproteobacteria,2MP9Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_C14
LZS1_k127_8083466_1	1038860.AXAP01000101_gene5276	7.397e-42	175.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2TW3U@28211|Alphaproteobacteria,3JUDT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS1_k127_8083466_2	1121033.AUCF01000001_gene1937	9.899e-39	162.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2TW3U@28211|Alphaproteobacteria,2JR9D@204441|Rhodospirillales	204441|Rhodospirillales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS1_k127_8083466_4	1540221.JQNI01000002_gene2943	9.469e-28	113.0	COG1136@1|root,COG1136@2|Bacteria,1WJ97@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS1_k127_808978_8	1002804.HBZC1_01580	3.441e-10	64.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2YN1A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS1_k127_808978_6	1121405.dsmv_0796	1.172e-64	233.0	COG0287@1|root,COG0287@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
LZS1_k127_808978_5	862908.BMS_2694	2.858e-74	268.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
LZS1_k127_808978_7	68199.JNZO01000001_gene1153	1.166e-18	101.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
LZS1_k127_808978_1	272123.Anacy_4329	3.224e-137	448.0	COG0722@1|root,COG0722@2|Bacteria,1G35W@1117|Cyanobacteria,1HIMM@1161|Nostocales	1117|Cyanobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroF	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS1_k127_808978_3	404589.Anae109_3723	3.321e-112	372.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,2YTTU@29|Myxococcales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
LZS1_k127_808978_4	290397.Adeh_1627	1.334e-111	373.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,2YU09@29|Myxococcales	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
LZS1_k127_808978_2	530564.Psta_0806	2.553e-128	419.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
LZS1_k127_808978_0	518766.Rmar_0337	2.212e-186	593.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,1FIWT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Pyruvate:ferredoxin oxidoreductase core domain II	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
LZS1_k127_8102682_2	641112.ACOK01000094_gene982	1.141e-09	73.0	COG2710@1|root,COG2710@2|Bacteria,1TP8Z@1239|Firmicutes,249HR@186801|Clostridia,3WHZD@541000|Ruminococcaceae	186801|Clostridia	C	Nitrogenase component 1	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
LZS1_k127_8102682_0	717606.PaecuDRAFT_4696	9.341e-18	98.0	COG0535@1|root,COG0535@2|Bacteria,1W6UW@1239|Firmicutes,4I6IK@91061|Bacilli,26T8B@186822|Paenibacillaceae	91061|Bacilli	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS1_k127_8102682_1	331678.Cphamn1_0679	1.254e-14	88.0	COG0641@1|root,COG0641@2|Bacteria,1FEDJ@1090|Chlorobi	1090|Chlorobi	C	PFAM Radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_810536_2	1131269.AQVV01000015_gene2042	1.384e-24	105.0	COG3369@1|root,COG3369@2|Bacteria	2|Bacteria	I	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
LZS1_k127_810536_1	203122.Sde_0886	6.823e-35	141.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,46AQ1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
LZS1_k127_810536_0	1254432.SCE1572_28455	4.569e-240	757.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2X37C@28221|Deltaproteobacteria,2YUQZ@29|Myxococcales	28221|Deltaproteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
LZS1_k127_8124822_5	760568.Desku_2206	3.27e-07	63.0	COG2710@1|root,COG2710@2|Bacteria,1TPJX@1239|Firmicutes,24AW6@186801|Clostridia,264RJ@186807|Peptococcaceae	186801|Clostridia	C	COG2710 Nitrogenase molybdenum-iron protein alpha and beta	-	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
LZS1_k127_8124822_6	431943.CKL_1034	4.967e-07	63.0	COG2710@1|root,COG2710@2|Bacteria,1TP8Z@1239|Firmicutes,249HR@186801|Clostridia,36ECK@31979|Clostridiaceae	186801|Clostridia	C	Nitrogenase molybdenum-iron protein, alpha	-	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
LZS1_k127_8124822_7	298653.Franean1_2825	0.0002546	52.0	COG0535@1|root,COG0535@2|Bacteria,2H32V@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS1_k127_8124822_1	755731.Clo1100_3110	7.232e-48	190.0	COG0535@1|root,COG0535@2|Bacteria,1UZPV@1239|Firmicutes,24ASI@186801|Clostridia,36NUI@31979|Clostridiaceae	186801|Clostridia	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS1_k127_8124822_0	1192034.CAP_2191	1.204e-83	303.0	COG0535@1|root,COG0535@2|Bacteria,1QAR5@1224|Proteobacteria,4358Z@68525|delta/epsilon subdivisions,2WZK5@28221|Deltaproteobacteria,2Z2AQ@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_8124822_2	391625.PPSIR1_25596	7.426e-17	95.0	COG0535@1|root,COG0535@2|Bacteria,1QAR5@1224|Proteobacteria,4358Z@68525|delta/epsilon subdivisions,2WZK5@28221|Deltaproteobacteria,2Z2AQ@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS1_k127_8124822_4	644282.Deba_2507	4.001e-10	73.0	COG0535@1|root,COG0535@2|Bacteria,1ND1B@1224|Proteobacteria,42RQW@68525|delta/epsilon subdivisions,2WNGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS1_k127_8124822_3	397287.C807_01733	1.444e-15	91.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,27I8D@186928|unclassified Lachnospiraceae	186801|Clostridia	C	4Fe-4S single cluster domain	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS1_k127_8137861_5	1304883.KI912532_gene2121	3.354e-06	55.0	COG2911@1|root,COG2911@2|Bacteria,1QWGG@1224|Proteobacteria,2WGYX@28216|Betaproteobacteria,2KZX3@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
LZS1_k127_8137861_0	1121434.AULY01000007_gene1436	2.554e-54	211.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2WPG9@28221|Deltaproteobacteria,2M8W5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS1_k127_8137861_4	2903.EOD09483	3.73e-09	68.0	COG0170@1|root,KOG4453@2759|Eukaryota	2759|Eukaryota	I	phytol kinase activity	DGK1	GO:0003674,GO:0003824,GO:0004143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006629,GO:0006644,GO:0006650,GO:0006654,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046473,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0098827,GO:1901576	2.7.1.174	ko:K16368	ko00564,ko01100,ko01110,map00564,map01100,map01110	-	R09944	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP_transf_1
LZS1_k127_8137861_2	1122222.AXWR01000022_gene358	4.667e-16	91.0	COG0745@1|root,COG0745@2|Bacteria,1WM5W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K18144	ko01501,map01501	M00649,M00655	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS1_k127_8137861_1	1499499.EV06_0610	2.095e-20	95.0	COG2197@1|root,COG2197@2|Bacteria,1G1TZ@1117|Cyanobacteria,1MKWM@1212|Prochloraceae	1117|Cyanobacteria	K	response regulator	ycf29	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS1_k127_823025_1	379066.GAU_2716	1.008e-33	138.0	COG1051@1|root,COG1051@2|Bacteria,1ZU0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS1_k127_823025_4	1247649.D560_0380	6.212e-21	107.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,3T3YG@506|Alcaligenaceae	28216|Betaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
LZS1_k127_823025_2	1235797.C816_01002	8.666e-27	116.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,2N67U@216572|Oscillospiraceae	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS1_k127_823025_5	221027.JO40_07250	9.098e-10	70.0	COG1426@1|root,COG1426@2|Bacteria,2J61E@203691|Spirochaetes	203691|Spirochaetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
LZS1_k127_823025_6	519989.ECTPHS_10129	1.66e-09	68.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,1WXHE@135613|Chromatiales	135613|Chromatiales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
LZS1_k127_823025_0	1157490.EL26_05275	6.893e-124	425.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,277W0@186823|Alicyclobacillaceae	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
LZS1_k127_823025_3	1424334.W822_17205	1.728e-24	106.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,3T3YH@506|Alcaligenaceae	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
LZS1_k127_845686_5	1463858.JOHR01000012_gene2281	9.185e-06	54.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
LZS1_k127_845686_0	690850.Desaf_2739	7.16e-126	424.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2M8PX@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	TIGRFAM Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
LZS1_k127_845686_2	1095767.CAHD01000205_gene848	1.876e-114	379.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria	201174|Actinobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS1_k127_845686_4	1408436.JHXY01000011_gene1528	2.044e-13	79.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,25X65@186806|Eubacteriaceae	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
LZS1_k127_845686_3	1120917.AQXM01000059_gene619	4.394e-16	89.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,1W7T9@1268|Micrococcaceae	201174|Actinobacteria	K	Crp Fnr family	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS1_k127_845686_1	1454010.JEOE01000001_gene610	6.257e-117	388.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria	201174|Actinobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS1_k127_852639_4	1144275.COCOR_01429	2.99e-06	61.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS1_k127_852639_6	1519464.HY22_07730	1.191e-05	59.0	COG1572@1|root,COG1572@2|Bacteria,1FEWM@1090|Chlorobi	1090|Chlorobi	S	Propeptide_C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,Propeptide_C25
LZS1_k127_852639_7	459349.CLOAM1225	5.662e-05	57.0	COG2067@1|root,COG2067@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_852639_3	41431.PCC8801_0753	1.023e-08	67.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,NB-ARC,Peptidase_C14,Trypsin_2
LZS1_k127_852639_2	443143.GM18_0093	4.181e-42	162.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,42S8C@68525|delta/epsilon subdivisions,2WP10@28221|Deltaproteobacteria,43TU3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF480	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
LZS1_k127_852639_1	264462.Bd0975	7.623e-69	241.0	COG0500@1|root,COG2226@2|Bacteria,1QY1T@1224|Proteobacteria,42YBC@68525|delta/epsilon subdivisions,2MSW8@213481|Bdellovibrionales,2WUEA@28221|Deltaproteobacteria	213481|Bdellovibrionales	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_852639_0	264462.Bd0975	2.729e-73	259.0	COG0500@1|root,COG2226@2|Bacteria,1QY1T@1224|Proteobacteria,42YBC@68525|delta/epsilon subdivisions,2MSW8@213481|Bdellovibrionales,2WUEA@28221|Deltaproteobacteria	213481|Bdellovibrionales	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_852639_5	797302.Halru_0436	3.976e-06	53.0	COG1403@1|root,arCOG03898@2157|Archaea,2XW7H@28890|Euryarchaeota,23UA4@183963|Halobacteria	183963|Halobacteria	L	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS1_k127_860003_1	1123242.JH636434_gene5621	1.916e-128	419.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
LZS1_k127_860003_4	509190.Cseg_0208	2.696e-41	158.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,2U723@28211|Alphaproteobacteria,2KGF7@204458|Caulobacterales	204458|Caulobacterales	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
LZS1_k127_860003_5	765869.BDW_09295	1.3e-36	142.0	COG0735@1|root,COG0735@2|Bacteria,1Q2NI@1224|Proteobacteria,42SV3@68525|delta/epsilon subdivisions,2WPH8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS1_k127_860003_3	251221.35214307	7.455e-43	162.0	COG1592@1|root,COG1592@2|Bacteria,1G3UB@1117|Cyanobacteria	1117|Cyanobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin,Rubrerythrin
LZS1_k127_860003_0	1116472.MGMO_131c00050	0.0	1220.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1XG48@135618|Methylococcales	135618|Methylococcales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	-	-	-	-	-	-	-	-	-	-	peroxidase
LZS1_k127_860003_2	1123242.JH636435_gene793	4.725e-49	181.0	COG0415@1|root,COG0415@2|Bacteria,2IZKY@203682|Planctomycetes	203682|Planctomycetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
LZS1_k127_875363_2	573063.Metin_0805	4.295e-37	149.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,23QPZ@183939|Methanococci	183939|Methanococci	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS1_k127_875363_0	665956.HMPREF1032_02431	5.894e-47	175.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3WGN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
LZS1_k127_875363_1	1111069.TCCBUS3UF1_7270	1.944e-45	176.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1WJBW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
LZS1_k127_899293_4	1429916.X566_15330	1.758e-10	66.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,2UJIU@28211|Alphaproteobacteria,3K0ZQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	UPF0391 membrane protein	MA20_02060	-	-	-	-	-	-	-	-	-	-	-	DUF1328
LZS1_k127_899293_0	1003200.AXXA_29962	5.971e-47	181.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2VTKP@28216|Betaproteobacteria,3T7AZ@506|Alcaligenaceae	28216|Betaproteobacteria	O	Peroxiredoxin OsmC	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
LZS1_k127_899293_2	886293.Sinac_2917	6.016e-34	134.0	COG2154@1|root,COG2154@2|Bacteria,2J0CT@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
LZS1_k127_899293_1	234267.Acid_3599	3.596e-46	175.0	COG1225@1|root,COG1225@2|Bacteria,3Y4W0@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS1_k127_899293_3	396588.Tgr7_0172	8.901e-27	111.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ2Z@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS1_k127_943484_0	370438.PTH_1811	2.428e-94	319.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS1_k127_943484_1	1261545.MBE-HAL_1350	1.037e-88	303.0	COG0167@1|root,arCOG00603@2157|Archaea,2XTMB@28890|Euryarchaeota,23SDB@183963|Halobacteria	183963|Halobacteria	F	Dihydroorotate dehydrogenase	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS1_k127_943484_2	313628.LNTAR_13927	4.48e-52	196.0	COG0284@1|root,COG0284@2|Bacteria	2|Bacteria	F	orotidine-5'-phosphate decarboxylase activity	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750	OMPdecase
LZS1_k127_992169_1	1123252.ATZF01000012_gene3741	2.699e-94	329.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,27BPG@186824|Thermoactinomycetaceae	91061|Bacilli	J	tRNA (Uracil-5-)-methyltransferase	rumA	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
LZS1_k127_992169_2	136993.KB900626_gene1889	0.0004168	51.0	COG0308@1|root,COG0308@2|Bacteria,1QW52@1224|Proteobacteria,2UHYM@28211|Alphaproteobacteria,36ZB4@31993|Methylocystaceae	28211|Alphaproteobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS1_k127_992169_0	1177179.A11A3_03994	1.413e-108	383.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1XHBW@135619|Oceanospirillales	135619|Oceanospirillales	P	P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
## 2678 queries scanned
## Total time (seconds): 147.60240125656128
## Rate: 18.14 q/s