## Thu Oct 17 02:55:09 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/LZS2_bin.15.fa -m mmseqs --itype genome -o LZS2_bin.15 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/LZS2_bin.15 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
LZS2_k127_1039527_5	1396141.BATP01000003_gene4975	6.809e-22	105.0	COG1361@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,46WJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS2_k127_1039527_3	316274.Haur_0818	3.727e-45	173.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_1039527_1	483219.LILAB_07765	1.045e-68	265.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2Z2WE@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
LZS2_k127_1039527_0	326427.Cagg_0838	2.943e-146	477.0	COG0642@1|root,COG2205@2|Bacteria	326427.Cagg_0838|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1039527_2	926569.ANT_27940	5.424e-64	229.0	COG1647@1|root,COG1647@2|Bacteria,2G73V@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
LZS2_k127_1039527_4	926550.CLDAP_17420	2.05e-24	103.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
LZS2_k127_1052538_4	357808.RoseRS_1784	7.09e-18	91.0	COG5305@1|root,COG5305@2|Bacteria,2GAHI@200795|Chloroflexi,3765S@32061|Chloroflexia	32061|Chloroflexia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1052538_3	926550.CLDAP_16420	4.996e-43	165.0	COG0741@1|root,COG1470@1|root,COG0741@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,NPCBM_assoc,Phage_HK97_TLTM,SLT
LZS2_k127_1052538_2	926569.ANT_04690	3.128e-138	449.0	COG1079@1|root,COG1079@2|Bacteria,2G6CY@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS2_k127_1052538_1	926569.ANT_04700	2.911e-138	451.0	COG4603@1|root,COG4603@2|Bacteria,2G686@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS2_k127_1052538_0	926569.ANT_04710	6.484e-203	644.0	COG3845@1|root,COG3845@2|Bacteria,2G68B@200795|Chloroflexi	200795|Chloroflexi	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
LZS2_k127_1102884_1	404589.Anae109_1809	2.171e-24	106.0	COG4585@1|root,COG4585@2|Bacteria,1N0JE@1224|Proteobacteria,42UG3@68525|delta/epsilon subdivisions,2WQFT@28221|Deltaproteobacteria,2Z1DF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
LZS2_k127_1102884_0	1382306.JNIM01000001_gene1045	5.922e-67	234.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_1102884_3	318167.Sfri_3130	1.364e-12	77.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RYPM@1236|Gammaproteobacteria,2Q8MP@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
LZS2_k127_1102884_2	1120985.AUMI01000018_gene2921	1.689e-16	85.0	COG5557@1|root,COG5557@2|Bacteria,1TSZC@1239|Firmicutes,4H2Q6@909932|Negativicutes	909932|Negativicutes	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
LZS2_k127_1111866_0	926550.CLDAP_36890	0.0	1257.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS2_k127_1111866_1	926550.CLDAP_36880	6.969e-140	451.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS2_k127_1111866_6	216432.CA2559_05515	7.907e-13	70.0	COG0401@1|root,COG0401@2|Bacteria,4NUY1@976|Bacteroidetes,1I50E@117743|Flavobacteriia	976|Bacteroidetes	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
LZS2_k127_1111866_3	272134.KB731324_gene4831	1.077e-35	145.0	COG1075@1|root,COG1075@2|Bacteria,1G5J7@1117|Cyanobacteria	1117|Cyanobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1111866_2	102129.Lepto7375DRAFT_7693	1.25e-59	208.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS2_k127_1111866_7	166318.Syn8016DRAFT_1779	5.57e-08	56.0	COG3019@1|root,COG3019@2|Bacteria,1G5QE@1117|Cyanobacteria,1H1A8@1129|Synechococcus	1117|Cyanobacteria	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
LZS2_k127_1111866_4	1307761.L21SP2_1298	3.267e-33	133.0	2DSTU@1|root,33HDW@2|Bacteria	2|Bacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS2_k127_1131132_0	1128421.JAGA01000003_gene2831	1.38e-253	806.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS2_k127_1131132_1	1232410.KI421416_gene2631	1.012e-79	283.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,42NSR@68525|delta/epsilon subdivisions,2WR56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
LZS2_k127_1131440_1	880073.Calab_3009	1.182e-07	58.0	COG2208@1|root,COG2208@2|Bacteria,2NQW9@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	CHASE2,GAF_2,HATPase_c_2,SpoIIE
LZS2_k127_1131440_2	1500897.JQNA01000002_gene1352	7.631e-06	54.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2VJF0@28216|Betaproteobacteria,1K43E@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
LZS2_k127_1131440_0	1038922.PflQ2_3136	3.646e-40	151.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,1RP4F@1236|Gammaproteobacteria,1YSPW@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	CO	Thioredoxin-like	dipZ	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD
LZS2_k127_1132477_2	926550.CLDAP_35270	9.566e-161	515.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_1132477_0	316274.Haur_3627	4.673e-270	844.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi,37630@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_1132477_5	1128421.JAGA01000002_gene1312	2.499e-98	335.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
LZS2_k127_1132477_4	395493.BegalDRAFT_3427	2.966e-99	331.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
LZS2_k127_1132477_7	163908.KB235896_gene3912	4.708e-83	291.0	COG1578@1|root,COG1578@2|Bacteria,1G2U2@1117|Cyanobacteria,1HMF8@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function DUF89	-	-	-	-	-	-	-	-	-	-	-	-	DUF89
LZS2_k127_1132477_3	335543.Sfum_3098	2.702e-136	443.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WJ7X@28221|Deltaproteobacteria,2MQ7K@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Amino-transferase class IV	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_2853	Aminotran_4
LZS2_k127_1132477_1	926550.CLDAP_13690	1.744e-182	584.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
LZS2_k127_1132477_6	926569.ANT_27070	4.531e-95	323.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_1170488_7	177437.HRM2_01470	0.0005446	45.0	COG0225@1|root,COG0225@2|Bacteria,1N2DQ@1224|Proteobacteria,42UC3@68525|delta/epsilon subdivisions,2WQBZ@28221|Deltaproteobacteria,2MNC1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Peptide methionine sulfoxide reductase	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
LZS2_k127_1170488_1	56110.Oscil6304_3528	1.05e-127	416.0	COG0451@1|root,COG0451@2|Bacteria,1G0QH@1117|Cyanobacteria,1H7R6@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,5.1.3.2	ko:K01784,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS2_k127_1170488_6	316274.Haur_2627	2.139e-11	76.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Rhomboid,TPR_16,TPR_19,TPR_8
LZS2_k127_1170488_0	316274.Haur_3043	8.281e-148	476.0	COG2189@1|root,COG2189@2|Bacteria,2G7K2@200795|Chloroflexi,3756B@32061|Chloroflexia	32061|Chloroflexia	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
LZS2_k127_1170488_2	485913.Krac_11734	4.496e-122	413.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS2_k127_1170488_3	926560.KE387027_gene1021	5.039e-122	419.0	2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1170488_5	660470.Theba_2263	4.149e-13	83.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,PQQ_2,PQQ_3
LZS2_k127_1170488_4	96561.Dole_2249	6.326e-105	368.0	2E0M7@1|root,32W6F@2|Bacteria,1NB9Z@1224|Proteobacteria,42W6T@68525|delta/epsilon subdivisions,2WSFF@28221|Deltaproteobacteria,2MNT8@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1176712_0	926550.CLDAP_18660	4.964e-172	546.0	COG0535@1|root,COG0535@2|Bacteria,2G7WG@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
LZS2_k127_1176712_2	247156.NFA_53810	2.836e-10	74.0	COG1716@1|root,COG3629@1|root,COG1716@2|Bacteria,COG3629@2|Bacteria,2HEQI@201174|Actinobacteria,4FVV3@85025|Nocardiaceae	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,FHA,Trans_reg_C,Yop-YscD_cpl
LZS2_k127_1176712_1	926550.CLDAP_10530	1.662e-25	123.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_1182771_2	1293054.HSACCH_00487	6.163e-31	122.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WB8I@53433|Halanaerobiales	186801|Clostridia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
LZS2_k127_1182771_1	760192.Halhy_3735	1.115e-122	398.0	COG1082@1|root,COG1082@2|Bacteria,4NHJE@976|Bacteroidetes,1IWGQ@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS2_k127_1182771_0	452637.Oter_2881	3.106e-185	585.0	COG0673@1|root,COG0673@2|Bacteria,46U25@74201|Verrucomicrobia,3K7IT@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_1187939_5	926569.ANT_22870	5.086e-55	198.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
LZS2_k127_1187939_3	1173027.Mic7113_6136	6.318e-72	255.0	COG1226@1|root,COG1226@2|Bacteria,1G0WK@1117|Cyanobacteria,1H894@1150|Oscillatoriales	1117|Cyanobacteria	P	K transport	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
LZS2_k127_1187939_0	1128421.JAGA01000003_gene3086	4.457e-289	898.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS2_k127_1187939_4	926569.ANT_13830	7.578e-71	246.0	COG2738@1|root,COG2738@2|Bacteria,2G6KQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
LZS2_k127_1187939_1	926569.ANT_09340	8.454e-95	325.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74,3.4.21.107	ko:K04771,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_1187939_2	997296.PB1_08027	1.754e-77	264.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli,1ZBMX@1386|Bacillus	91061|Bacilli	F	thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iYO844.BSU37060	TK
LZS2_k127_1188169_2	926550.CLDAP_20690	8.732e-112	374.0	COG0577@1|root,COG0577@2|Bacteria,2G6RX@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
LZS2_k127_1188169_1	926550.CLDAP_29040	6.618e-115	378.0	COG1090@1|root,COG1090@2|Bacteria,2G69K@200795|Chloroflexi	200795|Chloroflexi	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
LZS2_k127_1188169_0	926550.CLDAP_29050	8.313e-136	445.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
LZS2_k127_1192774_1	926550.CLDAP_12370	1.01e-71	265.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1192774_2	926550.CLDAP_12350	6.187e-16	89.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
LZS2_k127_1192774_0	351607.Acel_1240	2.192e-79	273.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4ERYA@85013|Frankiales	201174|Actinobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS2_k127_1198883_1	870187.Thini_0749	5.25e-145	462.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,45ZPG@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
LZS2_k127_1198883_3	926550.CLDAP_36170	1.25e-109	369.0	COG1232@1|root,COG1232@2|Bacteria,2G83R@200795|Chloroflexi	200795|Chloroflexi	H	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS2_k127_1198883_0	765420.OSCT_2889	2.718e-212	690.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,376FV@32061|Chloroflexia	32061|Chloroflexia	M	Penicillin-Binding Protein C-terminus Family	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
LZS2_k127_1198883_6	926569.ANT_11780	1.984e-51	205.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_1198883_5	926569.ANT_11780	8.466e-52	205.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_1198883_7	357808.RoseRS_1088	1.888e-12	73.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_1198883_4	401526.TcarDRAFT_2406	2.393e-82	284.0	COG3804@1|root,COG3804@2|Bacteria,1TRNF@1239|Firmicutes,4H7KW@909932|Negativicutes	909932|Negativicutes	C	Dihydrodipicolinate reductase, N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DapB_N
LZS2_k127_1198883_2	485913.Krac_9449	2.007e-111	365.0	COG2721@1|root,COG2721@2|Bacteria,2G8E3@200795|Chloroflexi	200795|Chloroflexi	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	-	-	-	-	-	-	-	-	-	-	GD_AH_C
LZS2_k127_1206631_1	926560.KE387025_gene3982	1.162e-60	212.0	COG1136@1|root,COG1136@2|Bacteria,1WM2T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_1206631_4	926550.CLDAP_14460	4.53e-33	134.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS2_k127_1206631_6	339670.Bamb_1975	0.0003638	46.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
LZS2_k127_1206631_5	102232.GLO73106DRAFT_00006330	5.73e-22	101.0	2E7Q2@1|root,3325J@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
LZS2_k127_1206631_0	926550.CLDAP_08640	1.191e-130	428.0	COG1388@1|root,COG1506@1|root,COG1388@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,FecR,LysM,Peptidase_S9
LZS2_k127_1206631_2	926550.CLDAP_03020	2.794e-38	155.0	COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi	200795|Chloroflexi	M	peptidase C60 sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
LZS2_k127_1206631_3	926569.ANT_23120	1.725e-34	143.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
LZS2_k127_1209498_9	1174528.JH992893_gene6056	8.375e-16	83.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParB,ParBc
LZS2_k127_1209498_4	311424.DhcVS_1153	4.054e-40	159.0	COG0167@1|root,COG0167@2|Bacteria,2G6RH@200795|Chloroflexi,34CMM@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS2_k127_1209498_6	1382306.JNIM01000001_gene4133	4.173e-34	141.0	COG0543@1|root,COG0543@2|Bacteria,2G75X@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
LZS2_k127_1209498_5	1499967.BAYZ01000159_gene478	1.195e-36	149.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_1209498_3	926569.ANT_06870	3.571e-81	281.0	COG0111@1|root,COG0111@2|Bacteria,2G6KY@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS2_k127_1209498_2	903818.KI912269_gene107	3.998e-90	305.0	COG0646@1|root,COG0646@2|Bacteria,3Y7SY@57723|Acidobacteria	57723|Acidobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
LZS2_k127_1209498_7	383372.Rcas_2081	8.059e-24	110.0	2ERP6@1|root,33J8I@2|Bacteria,2G9YM@200795|Chloroflexi,377B0@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1209498_0	1167006.UWK_01324	1.348e-251	784.0	COG0031@1|root,COG0031@2|Bacteria,1QQKZ@1224|Proteobacteria,42PVJ@68525|delta/epsilon subdivisions,2WKKY@28221|Deltaproteobacteria,2MMPP@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
LZS2_k127_1209498_1	1167006.UWK_01323	1.581e-96	319.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_1210857_1	926569.ANT_28570	3.493e-52	187.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM_2,Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
LZS2_k127_1210857_0	1047013.AQSP01000113_gene740	2e-323	1011.0	COG1472@1|root,COG1472@2|Bacteria,2NNR4@2323|unclassified Bacteria	2|Bacteria	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
LZS2_k127_1217647_4	720554.Clocl_2252	6.394e-16	84.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WND5@541000|Ruminococcaceae	186801|Clostridia	G	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1,HHH_3
LZS2_k127_1217647_0	926550.CLDAP_03680	1.825e-150	482.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
LZS2_k127_1217647_2	289376.THEYE_A1018	4.696e-28	117.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
LZS2_k127_1217647_1	1027273.GZ77_10995	1.018e-73	256.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1XJ9M@135619|Oceanospirillales	135619|Oceanospirillales	S	hemolysin III	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
LZS2_k127_1217647_3	1123274.KB899414_gene3686	1.187e-26	122.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
LZS2_k127_1240212_0	485913.Krac_0962	3.024e-70	255.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
LZS2_k127_1244305_6	926550.CLDAP_07570	5.91e-70	249.0	COG0392@1|root,COG0392@2|Bacteria,2G96G@200795|Chloroflexi	200795|Chloroflexi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_1244305_13	383372.Rcas_2764	1.099e-22	101.0	2EV6B@1|root,33NM4@2|Bacteria,2G7I5@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1244305_5	1089550.ATTH01000001_gene798	1.52e-78	268.0	COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,4PIWG@976|Bacteroidetes,1FK0G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydro2,RibD_C
LZS2_k127_1244305_7	706587.Desti_2995	2.87e-67	236.0	COG1985@1|root,COG1985@2|Bacteria,1N4VZ@1224|Proteobacteria	1224|Proteobacteria	H	COG1985 Pyrimidine reductase, riboflavin biosynthesis	ribD2	-	1.1.1.193,3.5.4.26	ko:K00082,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
LZS2_k127_1244305_1	706587.Desti_2994	7.379e-123	403.0	COG1063@1|root,COG1063@2|Bacteria,1MW7C@1224|Proteobacteria,430WX@68525|delta/epsilon subdivisions,2WW1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
LZS2_k127_1244305_8	706587.Desti_2993	3.955e-60	209.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
LZS2_k127_1244305_3	706587.Desti_2992	3.684e-109	363.0	COG0438@1|root,COG0438@2|Bacteria,1P81Z@1224|Proteobacteria	1224|Proteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_1244305_4	706587.Desti_2991	4.345e-100	334.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,RrnaAD
LZS2_k127_1244305_9	477974.Daud_1879	4.689e-59	213.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,2608V@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS2_k127_1244305_12	1121428.DESHY_10193___1	2.582e-24	112.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,260T5@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
LZS2_k127_1244305_2	1128421.JAGA01000001_gene2209	6.547e-120	391.0	COG1082@1|root,COG1082@2|Bacteria,2NQZX@2323|unclassified Bacteria	2|Bacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
LZS2_k127_1244305_10	1122194.AUHU01000004_gene1468	1.711e-34	134.0	COG2755@1|root,COG2755@2|Bacteria,1N7J4@1224|Proteobacteria,1S9Y7@1236|Gammaproteobacteria,46CAF@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
LZS2_k127_1244305_0	937777.Deipe_3129	5.289e-159	510.0	COG0673@1|root,COG0673@2|Bacteria,1WM59@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_1244305_14	926567.TheveDRAFT_1259	6.474e-16	81.0	COG1802@1|root,COG1802@2|Bacteria,3TAW8@508458|Synergistetes	508458|Synergistetes	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
LZS2_k127_1253437_3	1499967.BAYZ01000080_gene956	1.46e-65	229.0	COG5012@1|root,COG5012@2|Bacteria,2NQTJ@2323|unclassified Bacteria	2|Bacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
LZS2_k127_1253437_1	1121468.AUBR01000040_gene1732	1.592e-82	293.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,42FH6@68295|Thermoanaerobacterales	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
LZS2_k127_1253437_4	1123024.AUII01000038_gene4083	1.256e-23	116.0	COG0685@1|root,COG0685@2|Bacteria,2H891@201174|Actinobacteria	201174|Actinobacteria	E	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
LZS2_k127_1253437_2	1120950.KB892833_gene4024	1.417e-66	236.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
LZS2_k127_1253437_0	469371.Tbis_2599	3.62e-187	590.0	COG1032@1|root,COG1032@2|Bacteria,2HW71@201174|Actinobacteria,4E7P4@85010|Pseudonocardiales	201174|Actinobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS2_k127_1257485_1	1123366.TH3_16674	7.104e-07	57.0	COG3126@1|root,COG3650@1|root,COG3126@2|Bacteria,COG3650@2|Bacteria,1N6BH@1224|Proteobacteria,2UNDZ@28211|Alphaproteobacteria,2JUW1@204441|Rhodospirillales	204441|Rhodospirillales	S	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	MliC,YscW
LZS2_k127_1257485_2	1499967.BAYZ01000159_gene545	1.51e-05	51.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_4_9,Exo_endo_phos,F5_F8_type_C,FIVAR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N
LZS2_k127_1257485_0	926550.CLDAP_29120	2.212e-122	394.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_1257874_4	1122947.FR7_3375	2.665e-29	119.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4H2Y2@909932|Negativicutes	909932|Negativicutes	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
LZS2_k127_1257874_1	926550.CLDAP_13030	8.111e-114	383.0	COG0128@1|root,COG0128@2|Bacteria,2G5TT@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
LZS2_k127_1257874_2	926550.CLDAP_21740	1.703e-75	263.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
LZS2_k127_1257874_0	926569.ANT_01870	9.042e-142	458.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS2_k127_1257874_3	526222.Desal_0909	2.744e-38	150.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42R3Z@68525|delta/epsilon subdivisions,2WN4D@28221|Deltaproteobacteria,2MGMW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
LZS2_k127_1266764_30	485916.Dtox_1979	0.0005033	50.0	COG3064@1|root,COG4886@1|root,COG3064@2|Bacteria,COG4886@2|Bacteria,1UZWC@1239|Firmicutes	1239|Firmicutes	M	Leucine-rich repeat (LRR) protein	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	ChW,DUF4430
LZS2_k127_1266764_22	1122221.JHVI01000007_gene2245	2.214e-47	185.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_1266764_15	1121382.JQKG01000012_gene139	6.033e-82	279.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_1266764_17	118166.JH976537_gene4842	1.035e-77	268.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HAGW@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
LZS2_k127_1266764_19	1128421.JAGA01000001_gene2255	1.204e-63	245.0	COG0515@1|root,COG0515@2|Bacteria	1128421.JAGA01000001_gene2255|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1266764_24	1521187.JPIM01000082_gene185	4.855e-29	124.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8VB@200795|Chloroflexi,375FX@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trans_reg_C
LZS2_k127_1266764_28	1453505.JASY01000008_gene797	4.342e-05	49.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,1HY0E@117743|Flavobacteriia,2NUZ0@237|Flavobacterium	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	bfce	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
LZS2_k127_1266764_9	479434.Sthe_1841	2.538e-109	362.0	COG0346@1|root,COG0346@2|Bacteria,2G5Y9@200795|Chloroflexi,27XVR@189775|Thermomicrobia	189775|Thermomicrobia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
LZS2_k127_1266764_21	1183438.GKIL_2897	1.28e-47	175.0	COG1846@1|root,COG1846@2|Bacteria,1G6XI@1117|Cyanobacteria	1117|Cyanobacteria	K	MarR family transcriptional	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
LZS2_k127_1266764_11	316274.Haur_1182	7.623e-109	365.0	COG1940@1|root,COG1940@2|Bacteria,2G7R1@200795|Chloroflexi,375G6@32061|Chloroflexia	32061|Chloroflexia	K	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
LZS2_k127_1266764_1	926569.ANT_08110	2.763e-205	649.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS2_k127_1266764_12	926569.ANT_08100	1.627e-104	346.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
LZS2_k127_1266764_0	357808.RoseRS_3616	2.667e-215	685.0	COG3525@1|root,COG3525@2|Bacteria,2G609@200795|Chloroflexi,376QW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
LZS2_k127_1266764_2	882082.SaccyDRAFT_3480	8.309e-185	609.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_1266764_3	621372.ACIH01000113_gene895	4.349e-159	533.0	COG1653@1|root,COG1653@2|Bacteria,1UY8X@1239|Firmicutes,4HT5T@91061|Bacilli,26RVV@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
LZS2_k127_1266764_6	649638.Trad_0845	1.012e-122	401.0	COG1175@1|root,COG1175@2|Bacteria,1WJJK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
LZS2_k127_1266764_10	1116369.KB890024_gene115	4.561e-109	359.0	COG0395@1|root,COG0395@2|Bacteria,1QHIK@1224|Proteobacteria,2U2IY@28211|Alphaproteobacteria,43I49@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K10119	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	BPD_transp_1
LZS2_k127_1266764_13	882082.SaccyDRAFT_3477	1.968e-102	344.0	COG0673@1|root,COG0673@2|Bacteria,2HS16@201174|Actinobacteria,4EBU2@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_1266764_7	882082.SaccyDRAFT_3476	1.279e-116	384.0	COG0673@1|root,COG0673@2|Bacteria,2IGWQ@201174|Actinobacteria,4EBPJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_1266764_25	1123242.JH636434_gene4858	1.16e-14	76.0	COG5426@1|root,COG5426@2|Bacteria,2J31F@203682|Planctomycetes	203682|Planctomycetes	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
LZS2_k127_1266764_8	926550.CLDAP_35980	1.374e-114	379.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
LZS2_k127_1266764_20	479434.Sthe_1973	1.031e-51	193.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi,27YAS@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS2_k127_1266764_23	632518.Calow_0974	7.418e-47	179.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,42EPR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM extracellular solute-binding protein family 1	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS2_k127_1266764_16	1167006.UWK_00832	1.669e-79	273.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2MJE6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
LZS2_k127_1266764_5	926550.CLDAP_24610	1.113e-151	488.0	COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
LZS2_k127_1266764_4	926550.CLDAP_39490	3.021e-157	517.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,2G7T5@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
LZS2_k127_1266764_29	1187851.A33M_0807	0.000126	52.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,dCache_1
LZS2_k127_1266764_18	323259.Mhun_2988	2.964e-65	231.0	COG0639@1|root,COG5607@1|root,arCOG01143@2157|Archaea,arCOG05139@2157|Archaea,2XUDG@28890|Euryarchaeota,2NAJW@224756|Methanomicrobia	224756|Methanomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,Metallophos_2
LZS2_k127_1266764_26	555779.Dthio_PD3359	1.005e-12	69.0	2CEZQ@1|root,33C4G@2|Bacteria,1P9ED@1224|Proteobacteria,432EU@68525|delta/epsilon subdivisions,2WYJ9@28221|Deltaproteobacteria,2MFPC@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1266764_14	926550.CLDAP_14970	2.283e-95	323.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
LZS2_k127_1266764_27	309803.CTN_0963	4.332e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,2GCUR@200918|Thermotogae	200918|Thermotogae	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_127084_0	926550.CLDAP_35110	3.456e-156	498.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS2_k127_127084_2	316274.Haur_3155	7.839e-61	238.0	COG0457@1|root,COG2723@1|root,COG0457@2|Bacteria,COG2723@2|Bacteria,2G77P@200795|Chloroflexi,374U0@32061|Chloroflexia	32061|Chloroflexia	G	Domain of unknown function (DUF4380)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107
LZS2_k127_127084_7	1121456.ATVA01000011_gene1772	1.21e-25	110.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,43BPD@68525|delta/epsilon subdivisions,2X70Q@28221|Deltaproteobacteria,2MF45@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
LZS2_k127_127084_6	1128421.JAGA01000002_gene276	5.756e-28	117.0	COG0792@1|root,COG0792@2|Bacteria,2NQ3C@2323|unclassified Bacteria	2|Bacteria	L	Uncharacterised protein family UPF0102	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
LZS2_k127_127084_3	688269.Theth_1877	8.506e-56	200.0	COG2110@1|root,COG2110@2|Bacteria,2GD2K@200918|Thermotogae	200918|Thermotogae	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
LZS2_k127_127084_4	255470.cbdbA1421	4.88e-32	132.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,34D41@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
LZS2_k127_127084_1	926550.CLDAP_23380	5.871e-69	252.0	COG0004@1|root,COG0004@2|Bacteria,2G5N8@200795|Chloroflexi	2|Bacteria	P	PFAM Rh family protein ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS2_k127_127084_5	1382306.JNIM01000001_gene1619	6.359e-31	125.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
LZS2_k127_1280918_1	228410.NE1899	2.11e-19	92.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VKEW@28216|Betaproteobacteria,3728H@32003|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_1280918_0	1246448.ANAZ01000013_gene1761	6.961e-232	727.0	COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,4EGGU@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
LZS2_k127_1284316_1	177437.HRM2_14260	1.383e-28	121.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MI6S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS,Response_reg,dCache_1
LZS2_k127_1284316_2	525897.Dbac_2829	6.188e-19	91.0	COG2204@1|root,COG2204@2|Bacteria,1NBTR@1224|Proteobacteria,42V7Q@68525|delta/epsilon subdivisions,2WR8M@28221|Deltaproteobacteria,2MBT7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_1284316_0	1121438.JNJA01000013_gene21	1.021e-33	146.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria,2M881@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
LZS2_k127_1284603_0	385682.AFSL01000072_gene1309	7.652e-09	67.0	COG1216@1|root,COG1216@2|Bacteria,4PCIG@976|Bacteroidetes,2FZZ9@200643|Bacteroidia,3XJNE@558415|Marinilabiliaceae	976|Bacteroidetes	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
LZS2_k127_1291671_1	263820.PTO0135	4.687e-103	372.0	COG0515@1|root,arCOG03682@2157|Archaea,2XWZP@28890|Euryarchaeota	28890|Euryarchaeota	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NosD,Pkinase
LZS2_k127_1291671_0	935948.KE386494_gene461	2.691e-124	413.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,42FU6@68295|Thermoanaerobacterales	186801|Clostridia	F	Amidohydrolase family	hydA	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1,Urease_alpha
LZS2_k127_1291671_2	357808.RoseRS_2307	6.906e-51	191.0	COG1366@1|root,COG1879@1|root,COG1366@2|Bacteria,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	PAS_7,Peripla_BP_4,STAS
LZS2_k127_1303405_3	926569.ANT_27790	1.374e-89	304.0	COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_1303405_10	926550.CLDAP_22180	4.102e-21	104.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_1303405_2	311424.DhcVS_1009	3.334e-104	352.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,34CUN@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
LZS2_k127_1303405_1	316274.Haur_0023	5.934e-223	714.0	COG0515@1|root,COG3087@1|root,COG0515@2|Bacteria,COG3087@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_1303405_6	926569.ANT_22580	2.067e-59	232.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
LZS2_k127_1303405_4	667014.Thein_1148	8.562e-70	243.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS2_k127_1303405_9	1033802.SSPSH_003191	4.614e-22	101.0	COG2921@1|root,COG2921@2|Bacteria	2|Bacteria	S	Belongs to the UPF0250 family	ybeD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
LZS2_k127_1303405_7	255470.cbdbA545	7.927e-55	210.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
LZS2_k127_1303405_11	926569.ANT_06190	2.438e-19	90.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_25,Trm112p
LZS2_k127_1303405_5	926550.CLDAP_16790	3.155e-67	235.0	COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS2_k127_1303405_8	1382306.JNIM01000001_gene720	2.157e-43	164.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
LZS2_k127_1333999_1	926550.CLDAP_32470	1.527e-16	88.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_1333999_0	926550.CLDAP_11940	1.379e-24	119.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_133810_0	489825.LYNGBM3L_45070	9.784e-168	531.0	COG0399@1|root,COG0399@2|Bacteria,1G47X@1117|Cyanobacteria,1H9EC@1150|Oscillatoriales	1117|Cyanobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_133810_4	1484460.JSWG01000003_gene797	1.149e-45	167.0	2ED2V@1|root,32VHB@2|Bacteria,4PG31@976|Bacteroidetes,1I9GE@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2568
LZS2_k127_133810_5	43989.cce_1552	7.899e-45	181.0	COG1664@1|root,COG1664@2|Bacteria,1G2TI@1117|Cyanobacteria	1117|Cyanobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS2_k127_133810_6	1288963.ADIS_3103	1.395e-39	159.0	2ET8I@1|root,33KSM@2|Bacteria,4NZEX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_133810_2	485913.Krac_7099	1.897e-74	266.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	ydfH	-	2.7.13.3	ko:K07675,ko:K11623	ko02020,map02020	M00473,M00484	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
LZS2_k127_133810_3	485913.Krac_3252	1.219e-73	254.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	ydfI	-	-	ko:K11624	ko02020,map02020	M00484	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_133810_7	1379281.AVAG01000018_gene1023	6.023e-38	147.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,42R80@68525|delta/epsilon subdivisions,2WMW6@28221|Deltaproteobacteria,2MARF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
LZS2_k127_133810_8	33898.JRHJ01000047_gene8434	9.185e-10	69.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_133810_1	765420.OSCT_0652	5.526e-94	321.0	COG1283@1|root,COG1283@2|Bacteria,2GABF@200795|Chloroflexi,374Y2@32061|Chloroflexia	32061|Chloroflexia	P	Na+/Pi-cotransporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_Pi_cotrans
LZS2_k127_1341545_1	933262.AXAM01000019_gene1105	4.423e-67	233.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria,2MJKK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_1341545_2	357808.RoseRS_2923	2.098e-40	157.0	COG1011@1|root,COG1011@2|Bacteria,2G979@200795|Chloroflexi,377GE@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_1341545_3	649638.Trad_1382	5.418e-28	118.0	COG0824@1|root,COG0824@2|Bacteria,1WKEF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
LZS2_k127_1341545_0	926550.CLDAP_02810	7.656e-227	719.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_1374672_0	479434.Sthe_1721	7.454e-239	764.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,27Y2U@189775|Thermomicrobia	189775|Thermomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS2_k127_1374672_2	926550.CLDAP_13320	3.333e-89	305.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_1374672_3	926569.ANT_11070	6.839e-72	254.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
LZS2_k127_1374672_1	926569.ANT_11080	5.873e-165	529.0	COG1486@1|root,COG1486@2|Bacteria,2G6IX@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
LZS2_k127_1374672_4	926569.ANT_16820	2.446e-68	250.0	COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi	200795|Chloroflexi	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS2_k127_1374672_5	7918.ENSLOCP00000020705	1.472e-51	187.0	COG1437@1|root,KOG2589@2759|Eukaryota,3A4QC@33154|Opisthokonta,3BRFI@33208|Metazoa,3D8WI@33213|Bilateria,48EHS@7711|Chordata,49BAX@7742|Vertebrata,4A3UR@7898|Actinopterygii	33208|Metazoa	F	CYTH domain	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
LZS2_k127_1374672_6	926550.CLDAP_39210	0.0003504	44.0	COG0824@1|root,COG0824@2|Bacteria,2G9PJ@200795|Chloroflexi	200795|Chloroflexi	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
LZS2_k127_1392517_1	926569.ANT_09480	6.198e-58	218.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
LZS2_k127_1392517_0	1382306.JNIM01000001_gene1813	1.973e-174	567.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS2_k127_1396272_0	926550.CLDAP_17820	3.004e-97	325.0	COG0370@1|root,COG0370@2|Bacteria,2G5RW@200795|Chloroflexi	200795|Chloroflexi	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
LZS2_k127_1396272_2	926550.CLDAP_17830	3.941e-15	78.0	COG3355@1|root,COG3355@2|Bacteria,2G9N3@200795|Chloroflexi	200795|Chloroflexi	K	FeoC like transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FeoC
LZS2_k127_1396272_1	234267.Acid_3566	6.151e-86	295.0	COG3823@1|root,COG3823@2|Bacteria,3Y4G6@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
LZS2_k127_1396272_4	445335.CBN_2345	0.0006582	53.0	COG1807@1|root,COG1807@2|Bacteria,1UYMG@1239|Firmicutes,247PB@186801|Clostridia,36W4G@31979|Clostridiaceae	186801|Clostridia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_1396272_3	1121918.ARWE01000001_gene3039	2.127e-13	72.0	COG0668@1|root,COG0668@2|Bacteria,1PMY3@1224|Proteobacteria,42M4K@68525|delta/epsilon subdivisions,2WWCN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_1399834_0	926550.CLDAP_30450	8.421e-194	625.0	COG0607@1|root,COG0659@1|root,COG0607@2|Bacteria,COG0659@2|Bacteria,2G83D@200795|Chloroflexi	200795|Chloroflexi	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Rhodanese,STAS,Sulfate_transp
LZS2_k127_1399834_5	1123376.AUIU01000012_gene1459	1.218e-91	314.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	4.1.1.45	ko:K03392,ko:K07045	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
LZS2_k127_1399834_9	1121456.ATVA01000018_gene414	4.373e-54	202.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,42MU0@68525|delta/epsilon subdivisions,2WV0U@28221|Deltaproteobacteria,2MEFS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
LZS2_k127_1399834_8	1128421.JAGA01000002_gene1006	1.106e-58	226.0	COG1366@1|root,COG5000@1|root,COG1366@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3,2.7.7.7,3.1.3.3	ko:K02342,ko:K03407,ko:K07315,ko:K10909	ko00230,ko00240,ko01100,ko02020,ko02024,ko02030,ko03030,ko03430,ko03440,ko05111,map00230,map00240,map01100,map02020,map02024,map02030,map03030,map03430,map03440,map05111	M00260,M00506,M00513	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021,ko03032,ko03400	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,HisKA_3,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,RNase_T,STAS,SpoIIE,dCache_1
LZS2_k127_1399834_10	383372.Rcas_2373	3.503e-50	194.0	COG1366@1|root,COG2202@1|root,COG1366@2|Bacteria,COG2202@2|Bacteria,2GA9X@200795|Chloroflexi,376XC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	PAS_3,PAS_4,STAS
LZS2_k127_1399834_15	1157638.KB892170_gene133	9.479e-14	77.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS
LZS2_k127_1399834_12	316274.Haur_2684	5.745e-31	126.0	COG2172@1|root,COG2172@2|Bacteria,2GBSX@200795|Chloroflexi,375PM@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
LZS2_k127_1399834_13	715451.ambt_02580	7.958e-25	122.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	-
LZS2_k127_1399834_16	871963.Desdi_1143	0.0003208	52.0	2CEA6@1|root,32D7X@2|Bacteria,1V9H5@1239|Firmicutes,24KZA@186801|Clostridia,26222@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1399834_4	383372.Rcas_4129	5.789e-98	343.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_1399834_1	706587.Desti_0850	1.862e-149	521.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_1399834_3	646529.Desaci_0102	1.38e-113	380.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
LZS2_k127_1399834_6	639282.DEFDS_1384	1.036e-81	287.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
LZS2_k127_1399834_7	706587.Desti_4591	1.433e-61	235.0	COG3303@1|root,COG3303@2|Bacteria,1QX6Q@1224|Proteobacteria,42MHA@68525|delta/epsilon subdivisions,2WMF3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
LZS2_k127_1399834_2	926569.ANT_21940	5.585e-149	490.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
LZS2_k127_1399834_11	926569.ANT_21930	4.553e-48	180.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.81,3.2.1.97	ko:K01219,ko:K17624	-	-	-	-	ko00000,ko01000	-	GH101	-	Big_2,CBM_6,Cytochrome_C7,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,WxL
LZS2_k127_1405758_0	643473.KB235930_gene3727	8.702e-31	141.0	COG0457@1|root,COG1672@1|root,COG4249@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG4249@2|Bacteria,1G3A4@1117|Cyanobacteria,1HQV6@1161|Nostocales	1117|Cyanobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22
LZS2_k127_1405758_2	330214.NIDE0516	4.394e-14	84.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
LZS2_k127_1408564_5	926550.CLDAP_34380	9.263e-75	261.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_1408564_0	1521187.JPIM01000171_gene3730	0.0	1227.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,3751P@32061|Chloroflexia	32061|Chloroflexia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS2_k127_1408564_11	1408424.JHYI01000006_gene507	7.973e-15	85.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0761 family	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS2_k127_1408564_9	1173263.Syn7502_02053	1.179e-20	99.0	COG3881@1|root,COG3881@2|Bacteria,1G23A@1117|Cyanobacteria,1H2QG@1129|Synechococcus	1117|Cyanobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
LZS2_k127_1408564_14	1232410.KI421413_gene578	2.107e-09	64.0	COG5637@1|root,COG5637@2|Bacteria,1RHZP@1224|Proteobacteria,4308Q@68525|delta/epsilon subdivisions,2WVIQ@28221|Deltaproteobacteria,43UZP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Polyketide_cyc
LZS2_k127_1408564_7	866895.HBHAL_1326	5.136e-43	160.0	COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3NEHQ@45667|Halobacillus	91061|Bacilli	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
LZS2_k127_1408564_1	357808.RoseRS_3396	0.0	1018.0	COG0567@1|root,COG0567@2|Bacteria,2G638@200795|Chloroflexi,3763K@32061|Chloroflexia	32061|Chloroflexia	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
LZS2_k127_1408564_3	479434.Sthe_2057	4.862e-133	436.0	COG0508@1|root,COG0508@2|Bacteria,2G7SG@200795|Chloroflexi,27XXQ@189775|Thermomicrobia	189775|Thermomicrobia	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS2_k127_1408564_2	945713.IALB_2739	2.107e-232	732.0	COG0114@1|root,COG0114@2|Bacteria	2|Bacteria	C	fumarate hydratase activity	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS2_k127_1408564_4	247490.KSU1_C1034	8.463e-75	259.0	COG3861@1|root,COG3861@2|Bacteria,2IZRE@203682|Planctomycetes	203682|Planctomycetes	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	PRC
LZS2_k127_1408564_6	1340493.JNIF01000004_gene141	4.651e-60	216.0	COG3861@1|root,COG3861@2|Bacteria	2|Bacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	PRC
LZS2_k127_1408564_12	443218.AS9A_2168	1.515e-13	78.0	COG3832@1|root,COG3832@2|Bacteria,2GVS1@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
LZS2_k127_1408564_13	588581.Cpap_3066	3.593e-13	76.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,24K3N@186801|Clostridia,3WIM0@541000|Ruminococcaceae	186801|Clostridia	T	TIGRFAM sporulation protein, yteA family	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
LZS2_k127_1408564_8	1173023.KE650771_gene5565	1.173e-35	136.0	COG3344@1|root,COG3344@2|Bacteria,1G065@1117|Cyanobacteria,1JHHS@1189|Stigonemataceae	1117|Cyanobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
LZS2_k127_1411934_18	118166.JH976538_gene5295	3.52e-39	157.0	COG3861@1|root,COG3861@2|Bacteria,1GE1R@1117|Cyanobacteria	1117|Cyanobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1411934_19	1341646.CBMO010000115_gene2153	1.21e-38	159.0	COG0628@1|root,COG0628@2|Bacteria,2HT12@201174|Actinobacteria,2337A@1762|Mycobacteriaceae	201174|Actinobacteria	S	AI-2E family transporter	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS2_k127_1411934_24	1333507.AUTQ01000094_gene520	1.554e-28	123.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,2Q0Z1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
LZS2_k127_1411934_8	1123399.AQVE01000001_gene529	1.63e-77	268.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS2_k127_1411934_4	324602.Caur_0631	8.987e-134	445.0	COG0661@1|root,COG0661@2|Bacteria,2G6DN@200795|Chloroflexi,376TQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC-1 domain protein	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
LZS2_k127_1411934_20	357808.RoseRS_1669	2.189e-38	166.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria,2G805@200795|Chloroflexi	200795|Chloroflexi	T	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
LZS2_k127_1411934_14	646529.Desaci_4568	9.75e-52	188.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,261PA@186807|Peptococcaceae	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
LZS2_k127_1411934_2	1157490.EL26_22105	3.277e-157	508.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,277WJ@186823|Alicyclobacillaceae	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
LZS2_k127_1411934_7	926569.ANT_16610	2.105e-79	270.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS2_k127_1411934_12	926550.CLDAP_06930	1.938e-58	222.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi	200795|Chloroflexi	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
LZS2_k127_1411934_6	926550.CLDAP_21010	8.308e-101	349.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
LZS2_k127_1411934_9	926550.CLDAP_21020	1.473e-70	245.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_1411934_26	926550.CLDAP_21040	2.246e-27	115.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Biotin_lipoyl_2,Response_reg
LZS2_k127_1411934_32	926569.ANT_22100	6.593e-19	89.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
LZS2_k127_1411934_28	926569.ANT_22090	5.523e-26	111.0	COG1006@1|root,COG1006@2|Bacteria	2|Bacteria	P	Multisubunit Na H antiporter MnhC subunit	mnhC	-	1.6.5.3	ko:K00340,ko:K05567	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Oxidored_q2
LZS2_k127_1411934_0	926569.ANT_22080	4.278e-230	725.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	926569.ANT_22080|-	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1411934_3	926569.ANT_22070	3.712e-146	479.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	mrpD	-	1.6.5.3	ko:K00342,ko:K00343,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
LZS2_k127_1411934_10	926569.ANT_22050	2.015e-69	239.0	COG3260@1|root,COG3260@2|Bacteria,2G8XX@200795|Chloroflexi	200795|Chloroflexi	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	echC	-	-	ko:K14088	-	-	-	-	ko00000	-	-	-	Oxidored_q6
LZS2_k127_1411934_23	926569.ANT_22040	1.977e-30	128.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
LZS2_k127_1411934_1	926569.ANT_22030	1.77e-183	580.0	COG3261@1|root,COG3261@2|Bacteria,2G8BA@200795|Chloroflexi	200795|Chloroflexi	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	ko:K14090	-	-	-	-	ko00000	-	-	-	Complex1_49kDa,NiFeSe_Hases
LZS2_k127_1411934_5	926569.ANT_22020	2.236e-127	414.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS2_k127_1411934_17	926569.ANT_22010	2.579e-43	166.0	COG1143@1|root,COG1143@2|Bacteria,2G9SP@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	ko:K14091	-	-	-	-	ko00000	-	-	-	Fer4
LZS2_k127_1411934_27	926569.ANT_22000	5.074e-27	117.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	-	-	3.4.23.51	ko:K00442,ko:K08315	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000,ko01002	-	-	-	HycI
LZS2_k127_1411934_13	383372.Rcas_0886	1.147e-53	216.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,Response_reg
LZS2_k127_1411934_29	1121918.ARWE01000001_gene1548	1.818e-24	120.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_1411934_15	316067.Geob_1719	1.113e-50	203.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
LZS2_k127_1411934_21	1028307.EAE_14905	3.655e-34	141.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,1RQAV@1236|Gammaproteobacteria,3X3GI@547|Enterobacter	1236|Gammaproteobacteria	K	Two component transcriptional regulator, winged helix family	walR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_1411934_30	517418.Ctha_2358	1.784e-22	102.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
LZS2_k127_1411934_22	316274.Haur_0593	5.272e-32	128.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_1411934_16	926569.ANT_11840	1.545e-49	180.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_1411934_34	1173027.Mic7113_1213	3.462e-10	75.0	COG2203@1|root,COG2203@2|Bacteria,1G172@1117|Cyanobacteria,1HA3R@1150|Oscillatoriales	1117|Cyanobacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PAS,PAS_3
LZS2_k127_1411934_11	926569.ANT_11830	4.912e-64	252.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
LZS2_k127_1411934_25	926569.ANT_11820	3.876e-28	128.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
LZS2_k127_1411934_33	926569.ANT_11800	3.099e-17	94.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
LZS2_k127_142673_2	1123277.KB893182_gene4743	3.927e-14	84.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47KK7@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
LZS2_k127_142673_1	180332.JTGN01000020_gene1191	7.296e-19	100.0	COG0407@1|root,COG0407@2|Bacteria,1W13C@1239|Firmicutes,24TPG@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
LZS2_k127_142673_0	867903.ThesuDRAFT_02242	6.124e-41	157.0	COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,24K8U@186801|Clostridia	186801|Clostridia	C	Cytochrome b subunit of the bc	-	-	-	ko:K00412,ko:K02635	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrome_B
LZS2_k127_1440097_4	926550.CLDAP_15060	7.887e-73	246.0	COG1233@1|root,COG1233@2|Bacteria,2G5ZA@200795|Chloroflexi	200795|Chloroflexi	C	PFAM amine oxidase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
LZS2_k127_1440097_1	189425.PGRAT_25475	1.47e-142	459.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,26RSM@186822|Paenibacillaceae	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
LZS2_k127_1440097_3	926550.CLDAP_24890	5.466e-115	380.0	COG0809@1|root,COG0809@2|Bacteria,2G5UZ@200795|Chloroflexi	200795|Chloroflexi	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
LZS2_k127_1440097_0	1304880.JAGB01000001_gene694	2.206e-156	508.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
LZS2_k127_1440097_2	697281.Mahau_0316	2.19e-126	411.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_144988_4	926569.ANT_17770	1.176e-20	92.0	COG1905@1|root,COG1905@2|Bacteria,2G6Q5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334,ko:K05586	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
LZS2_k127_144988_3	545693.BMQ_3986	1.586e-34	139.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4HDFU@91061|Bacilli,1ZPV1@1386|Bacillus	91061|Bacilli	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
LZS2_k127_144988_1	926569.ANT_17780	3.474e-62	218.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	EAL,GAF_2,GAPES3,GGDEF,PAS_4,PAS_8,PAS_9,RNase_T,SpoIIE,dCache_1
LZS2_k127_144988_2	926569.ANT_17790	3.54e-38	147.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K17992	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
LZS2_k127_144988_0	926569.ANT_17800	9.957e-234	730.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	-	-	1.6.5.3	ko:K00335,ko:K05587	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
LZS2_k127_14569_14	1089544.KB912942_gene4845	2.635e-18	85.0	COG1695@1|root,COG4832@1|root,COG1695@2|Bacteria,COG4832@2|Bacteria,2GN4K@201174|Actinobacteria,4E0H0@85010|Pseudonocardiales	201174|Actinobacteria	K	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
LZS2_k127_14569_8	394221.Mmar10_1682	4.974e-54	215.0	COG2730@1|root,COG2730@2|Bacteria,1PUWU@1224|Proteobacteria,2V6EP@28211|Alphaproteobacteria,43ZQQ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_14569_9	402626.Rpic_2446	5.059e-53	212.0	COG2342@1|root,COG2342@2|Bacteria,1N2HD@1224|Proteobacteria,2W5MT@28216|Betaproteobacteria,1K6RZ@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycoside-hydrolase family GH114	-	-	6.1.1.16	ko:K01884	ko00970,map00970	M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Glyco_hydro_114
LZS2_k127_14569_11	926550.CLDAP_23360	3.414e-49	183.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8QX@200795|Chloroflexi	200795|Chloroflexi	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
LZS2_k127_14569_3	926550.CLDAP_23370	8.391e-108	360.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_14569_0	926569.ANT_13340	3.657e-152	518.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
LZS2_k127_14569_10	926550.CLDAP_17120	3.255e-50	202.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi	200795|Chloroflexi	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
LZS2_k127_14569_4	1123250.KB908408_gene2199	8.871e-68	237.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4H2EW@909932|Negativicutes	909932|Negativicutes	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
LZS2_k127_14569_1	926569.ANT_05010	1.995e-120	394.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
LZS2_k127_14569_16	485913.Krac_11333	3.75e-06	55.0	COG0745@1|root,COG2334@1|root,COG0745@2|Bacteria,COG2334@2|Bacteria,2G9TV@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_14569_6	316274.Haur_4259	1.238e-59	231.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
LZS2_k127_14569_2	1173024.KI912149_gene5561	7.472e-116	382.0	COG0430@1|root,COG0430@2|Bacteria,1G3A2@1117|Cyanobacteria	1117|Cyanobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
LZS2_k127_14569_7	765420.OSCT_2550	3.227e-58	211.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_14569_15	926550.CLDAP_36700	4.524e-16	89.0	COG2188@1|root,COG2188@2|Bacteria,2G6ST@200795|Chloroflexi	200795|Chloroflexi	K	SPTR D1CI93 Phophonate C-P lyase system transcriptional regulator PhnF, GntR family	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
LZS2_k127_14569_12	926550.CLDAP_04330	2.492e-27	123.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
LZS2_k127_14569_13	106370.Francci3_1432	3.072e-25	115.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria,4ET5K@85013|Frankiales	201174|Actinobacteria	S	Peptidase S16, lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
LZS2_k127_14569_5	1245475.ANAE01000178_gene4425	6.979e-66	235.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4EHK1@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_1489409_2	617140.AJZE01000055_gene3853	5.572e-40	153.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria,1XXKV@135623|Vibrionales	135623|Vibrionales	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
LZS2_k127_1489409_1	1128421.JAGA01000003_gene3248	8.467e-77	274.0	COG0477@1|root,COG2814@2|Bacteria,2NQ08@2323|unclassified Bacteria	2|Bacteria	EGP	MFS_1 like family	-	-	-	ko:K08151,ko:K08153	-	M00668,M00717	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
LZS2_k127_1489409_0	926550.CLDAP_20700	3.307e-93	311.0	COG1136@1|root,COG1136@2|Bacteria,2G6K8@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_149052_2	1042377.AFPJ01000008_gene1988	1.075e-12	70.0	COG4221@1|root,COG4221@2|Bacteria,1RF5D@1224|Proteobacteria,1S5AC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_149052_1	926550.CLDAP_04610	1.163e-51	201.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
LZS2_k127_149052_0	479434.Sthe_1183	1.076e-150	492.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
LZS2_k127_1504328_1	1123368.AUIS01000020_gene1109	2.652e-54	199.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RMUV@1236|Gammaproteobacteria,2NE6V@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE5,CHASE8,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
LZS2_k127_1504328_0	338969.Rfer_3893	3.258e-73	256.0	COG0834@1|root,COG5001@1|root,COG0834@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
LZS2_k127_1504328_2	880073.Calab_0584	3.708e-22	103.0	2AN2Z@1|root,31D0J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_151394_0	926550.CLDAP_18550	9.61e-216	684.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
LZS2_k127_151394_1	926569.ANT_04720	7.001e-167	535.0	COG1744@1|root,COG1744@2|Bacteria,2G6CN@200795|Chloroflexi	200795|Chloroflexi	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
LZS2_k127_151394_2	443254.Marpi_0697	0.000539	43.0	COG3845@1|root,COG3845@2|Bacteria,2GBZ4@200918|Thermotogae	200918|Thermotogae	S	PFAM ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
LZS2_k127_1520832_1	926550.CLDAP_36790	6.106e-78	266.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
LZS2_k127_1520832_3	573370.DMR_21790	6.303e-19	89.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2WRHX@28221|Deltaproteobacteria,2MCG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
LZS2_k127_1520832_4	497964.CfE428DRAFT_3040	1.31e-12	71.0	COG1872@1|root,COG1872@2|Bacteria,46T9T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
LZS2_k127_1520832_2	1128421.JAGA01000002_gene65	1.412e-19	94.0	2DRD4@1|root,33B9X@2|Bacteria,2NRTN@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1520832_0	671143.DAMO_2651	8.566e-172	548.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
LZS2_k127_1521166_6	1380355.JNIJ01000003_gene4161	9.364e-34	132.0	COG3695@1|root,COG3695@2|Bacteria,1RI04@1224|Proteobacteria	1224|Proteobacteria	L	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
LZS2_k127_1521166_0	316274.Haur_3525	3.711e-85	292.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	-	-	2.7.1.89	ko:K07251,ko:K18844	ko00730,ko01100,map00730,map01100	-	R02134	RC00002,RC00017	ko00000,ko00001,ko01000,ko01504	-	-	-	APH,Choline_kinase
LZS2_k127_1521166_1	1140.Synpcc7942_2140	1.151e-54	197.0	COG0295@1|root,COG0295@2|Bacteria,1GDSV@1117|Cyanobacteria	1117|Cyanobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
LZS2_k127_1521166_4	1131730.BAVI_23488	2.14e-36	145.0	2E58T@1|root,33017@2|Bacteria,1VARJ@1239|Firmicutes,4HKU9@91061|Bacilli,1ZHPC@1386|Bacillus	91061|Bacilli	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
LZS2_k127_1521166_8	118161.KB235919_gene6210	2.881e-29	124.0	2CHT5@1|root,32CXB@2|Bacteria,1G74Q@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Calci_bind_CcbP
LZS2_k127_1521166_3	1089553.Tph_c19370	3.308e-42	160.0	COG3007@1|root,COG3007@2|Bacteria,1UN0A@1239|Firmicutes,25GTR@186801|Clostridia	186801|Clostridia	I	enoyl-[acyl-carrier-protein] reductase (NADH) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1521166_7	1089553.Tph_c19360	1.307e-32	130.0	COG1669@1|root,COG1669@2|Bacteria,1VHUJ@1239|Firmicutes,24RYZ@186801|Clostridia,42HC9@68295|Thermoanaerobacterales	186801|Clostridia	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1521166_5	1137799.GZ78_23145	3.416e-36	144.0	2E7HH@1|root,33200@2|Bacteria,1P1NJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1521166_9	192952.MM_2239	1.401e-08	64.0	arCOG02138@1|root,arCOG02138@2157|Archaea,2Y5UV@28890|Euryarchaeota,2NBEE@224756|Methanomicrobia	224756|Methanomicrobia	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1521166_2	485913.Krac_1500	2.772e-44	171.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	ko:K02529,ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022,ko03000	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,TniQ
LZS2_k127_1521166_10	1192034.CAP_8201	1.382e-07	55.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	PAS_4,STAS
LZS2_k127_1529421_3	926550.CLDAP_10530	5.032e-11	74.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_1529421_1	383372.Rcas_0707	3.956e-63	237.0	COG0457@1|root,COG2723@1|root,COG0457@2|Bacteria,COG2723@2|Bacteria,2G77P@200795|Chloroflexi,374U0@32061|Chloroflexia	32061|Chloroflexia	G	Domain of unknown function (DUF4380)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107
LZS2_k127_1529421_2	926550.CLDAP_01650	3.251e-34	149.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K08307,ko:K19140	-	-	-	-	ko00000,ko01000,ko01011,ko02048	-	-	-	DDE_Tnp_1,DUF772
LZS2_k127_1529421_0	926550.CLDAP_29770	7.8e-166	549.0	COG0553@1|root,COG0553@2|Bacteria	2|Bacteria	L	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3883,Helicase_C,SNF2_N
LZS2_k127_1529421_4	1120959.ATXF01000007_gene2281	7.971e-06	50.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4FNB2@85023|Microbacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
LZS2_k127_1548620_9	886293.Sinac_4315	3.546e-51	186.0	COG0500@1|root,COG2226@2|Bacteria,2J382@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_1548620_14	329726.AM1_6084	3.049e-13	72.0	2DNVA@1|root,32ZBE@2|Bacteria,1GFXX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1548620_11	391625.PPSIR1_31263	1.815e-46	180.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKYM@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	GT	Phosphoenolpyruvate synthase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
LZS2_k127_1548620_15	1234679.BN424_3077	8.2e-13	81.0	COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli,27FWU@186828|Carnobacteriaceae	91061|Bacilli	O	Subtilase family	prtP	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	FIVAR,Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,SLAP,fn3_5
LZS2_k127_1548620_1	1303518.CCALI_02520	1.127e-177	572.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	ycf46	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
LZS2_k127_1548620_3	1499967.BAYZ01000095_gene4153	7.596e-134	438.0	COG0738@1|root,COG0738@2|Bacteria,2NQUK@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	araJ1	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_1548620_8	1125863.JAFN01000001_gene652	2.732e-51	192.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,LRV
LZS2_k127_1548620_13	383372.Rcas_3199	3.779e-22	100.0	COG0745@1|root,COG0745@2|Bacteria,2G9ZW@200795|Chloroflexi,377JC@32061|Chloroflexia	32061|Chloroflexia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_1548620_16	316274.Haur_2684	2.004e-12	72.0	COG2172@1|root,COG2172@2|Bacteria,2GBSX@200795|Chloroflexi,375PM@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
LZS2_k127_1548620_5	357808.RoseRS_0999	1.695e-84	301.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,2G716@200795|Chloroflexi,376VE@32061|Chloroflexia	32061|Chloroflexia	T	PFAM histidine kinase, HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,MCPsignal
LZS2_k127_1548620_17	1206725.BAFU01000059_gene617	2.645e-10	68.0	COG2172@1|root,COG2172@2|Bacteria,2IKM9@201174|Actinobacteria,4G0M5@85025|Nocardiaceae	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
LZS2_k127_1548620_18	497964.CfE428DRAFT_1773	7.976e-05	50.0	COG2197@1|root,COG4585@1|root,COG2197@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K07693,ko:K20971	ko02020,ko02025,map02020,map02025	M00479	-	-	ko00000,ko00001,ko00002,ko01001,ko02022	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA_3,MASE1,Response_reg
LZS2_k127_1548620_6	926550.CLDAP_08440	3.84e-82	278.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_1548620_12	926569.ANT_12480	1.108e-45	189.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
LZS2_k127_1548620_10	690850.Desaf_2561	1.198e-50	205.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_8,PAS_9,Response_reg
LZS2_k127_1548620_2	1123508.JH636439_gene1853	4.334e-138	473.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_1548620_0	644282.Deba_0431	1.136e-179	577.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
LZS2_k127_1548620_7	926569.ANT_30970	1.713e-73	252.0	COG1838@1|root,COG1838@2|Bacteria,2G74D@200795|Chloroflexi	200795|Chloroflexi	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
LZS2_k127_1548620_4	926569.ANT_30960	7.468e-108	357.0	COG1951@1|root,COG1951@2|Bacteria,2G6YI@200795|Chloroflexi	200795|Chloroflexi	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2	ko:K01676,ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
LZS2_k127_1590235_4	926550.CLDAP_11480	1.086e-20	95.0	COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
LZS2_k127_1590235_2	479434.Sthe_1819	5.939e-34	135.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi,27Z9F@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS2_k127_1590235_1	102129.Lepto7375DRAFT_1307	7.634e-39	149.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	mxaD	-	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Polyketide_cyc2
LZS2_k127_1590235_0	868131.MSWAN_0806	1.021e-91	310.0	COG1741@1|root,arCOG02935@2157|Archaea,2XU8Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
LZS2_k127_160716_7	404380.Gbem_2598	3.385e-30	134.0	COG0392@1|root,COG0392@2|Bacteria,1R98C@1224|Proteobacteria,42U6V@68525|delta/epsilon subdivisions,2WKTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_160716_10	686578.AFFX01000004_gene3626	2.871e-05	54.0	COG2197@1|root,COG2197@2|Bacteria,1Q0DT@1224|Proteobacteria,1RY1Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K07688,ko:K07690	ko02020,ko05133,map02020,map05133	M00477,M00697	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_160716_11	1321778.HMPREF1982_00645	0.0003525	44.0	COG0703@1|root,COG0703@2|Bacteria,1V25K@1239|Firmicutes,249JH@186801|Clostridia	186801|Clostridia	E	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
LZS2_k127_160716_1	1128421.JAGA01000003_gene3692	3.667e-107	361.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
LZS2_k127_160716_6	1265502.KB905933_gene2049	6.052e-41	167.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc,HAMP
LZS2_k127_160716_0	926550.CLDAP_37620	7.922e-242	763.0	COG1032@1|root,COG1032@2|Bacteria,2G5N0@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_160716_4	1122939.ATUD01000002_gene1172	1.852e-63	222.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CPVX@84995|Rubrobacteria	84995|Rubrobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
LZS2_k127_160716_2	1292035.H476_3096	5.539e-73	267.0	COG0127@1|root,COG0689@1|root,COG0127@2|Bacteria,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,25QCQ@186804|Peptostreptococcaceae	186801|Clostridia	F	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
LZS2_k127_160716_3	485913.Krac_5694	2.102e-65	244.0	COG0596@1|root,COG0596@2|Bacteria,2G91Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_160716_9	32057.KB217478_gene3274	4.498e-08	60.0	COG1366@1|root,COG1366@2|Bacteria,1G8M1@1117|Cyanobacteria,1HSDB@1161|Nostocales	1117|Cyanobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
LZS2_k127_160716_5	1463821.JOGR01000007_gene143	3.693e-59	219.0	COG4260@1|root,COG4260@2|Bacteria,2HUEV@201174|Actinobacteria,4EZMP@85014|Glycomycetales	201174|Actinobacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
LZS2_k127_160716_8	926569.ANT_20600	8.1e-20	96.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_160800_0	926569.ANT_14510	7.932e-177	565.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS2_k127_160800_1	926550.CLDAP_05310	3.992e-80	276.0	COG1319@1|root,COG1319@2|Bacteria,2G8QC@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS2_k127_160800_8	1120985.AUMI01000004_gene1324	5.183e-13	75.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_160800_7	1158182.KB905029_gene2378	9.194e-16	83.0	COG0664@1|root,COG0664@2|Bacteria,1RII7@1224|Proteobacteria	1224|Proteobacteria	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
LZS2_k127_160800_2	1148.1652811	8.328e-56	205.0	COG1028@1|root,COG1028@2|Bacteria,1G7CR@1117|Cyanobacteria,1H62Z@1142|Synechocystis	1117|Cyanobacteria	IQ	KR domain	gdh	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
LZS2_k127_160800_4	88036.EFJ32269	2.451e-50	188.0	2CJ2D@1|root,2QS3W@2759|Eukaryota,37R7G@33090|Viridiplantae,3GA1W@35493|Streptophyta	35493|Streptophyta	S	Sucrase/ferredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
LZS2_k127_160800_6	1321778.HMPREF1982_00603	7.562e-17	90.0	COG2204@1|root,COG2204@2|Bacteria,1V8B4@1239|Firmicutes,25BHN@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_19
LZS2_k127_160800_5	1118054.CAGW01000071_gene1857	3.903e-26	115.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,26SNK@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
LZS2_k127_160800_3	326427.Cagg_3700	2.982e-55	204.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,375KA@32061|Chloroflexia	32061|Chloroflexia	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
LZS2_k127_160851_0	926569.ANT_22790	3.225e-188	598.0	COG1271@1|root,COG1271@2|Bacteria,2G5TR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome bd ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
LZS2_k127_160851_1	316274.Haur_3758	5.566e-159	506.0	COG1294@1|root,COG1294@2|Bacteria,2G67G@200795|Chloroflexi,3772M@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
LZS2_k127_160851_2	700598.Niako_5751	1.303e-46	173.0	COG0454@1|root,COG0454@2|Bacteria,4PKSA@976|Bacteroidetes,1IT4P@117747|Sphingobacteriia	976|Bacteroidetes	K	Gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
LZS2_k127_160851_3	868595.Desca_2100	5.008e-39	150.0	COG4988@1|root,COG4988@2|Bacteria,1TQ1P@1239|Firmicutes,248SV@186801|Clostridia,2612P@186807|Peptococcaceae	186801|Clostridia	CO	Cysteine export CydDC family ABC transporter permease subunit ATP-binding protein CydD	cydD	-	-	ko:K06148,ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
LZS2_k127_1618820_1	1229909.NSED_00325	1.365e-30	129.0	COG0182@1|root,arCOG01123@2157|Archaea,41SF9@651137|Thaumarchaeota	651137|Thaumarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
LZS2_k127_1629306_2	180281.CPCC7001_2444	6.652e-149	475.0	COG3386@1|root,COG3386@2|Bacteria,1G05C@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
LZS2_k127_1629306_6	926550.CLDAP_06980	2.247e-43	164.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
LZS2_k127_1629306_1	926550.CLDAP_06970	4.506e-158	520.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
LZS2_k127_1629306_5	1128421.JAGA01000003_gene2708	2.263e-95	327.0	COG0438@1|root,COG0438@2|Bacteria,2NQV5@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_1629306_4	1307761.L21SP2_3206	1.192e-116	391.0	COG0438@1|root,COG0438@2|Bacteria,2J6VH@203691|Spirochaetes	203691|Spirochaetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
LZS2_k127_1629306_0	1499967.BAYZ01000100_gene3443	4.94e-198	629.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	ycjN	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_1629306_3	1499967.BAYZ01000100_gene3442	1.558e-135	439.0	COG1175@1|root,COG1175@2|Bacteria,2NR6V@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	ycjO	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02025,ko:K02026,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
LZS2_k127_1629306_7	1499967.BAYZ01000100_gene3441	0.0008562	43.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	ycjP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_1629643_1	383372.Rcas_4113	3.839e-114	376.0	COG0247@1|root,COG0247@2|Bacteria,2G7VD@200795|Chloroflexi,3754W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
LZS2_k127_1629643_0	926550.CLDAP_08300	7.401e-262	816.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi	200795|Chloroflexi	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
LZS2_k127_1629643_4	926569.ANT_04640	5.816e-29	125.0	COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1629643_3	1121428.DESHY_110048___1	7.489e-73	261.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,261CQ@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_1629643_5	1384056.N787_01095	9.899e-22	103.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1X6HN@135614|Xanthomonadales	135614|Xanthomonadales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS2_k127_1629643_2	357808.RoseRS_3094	9.68e-93	314.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi,37696@32061|Chloroflexia	32061|Chloroflexia	O	PFAM heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
LZS2_k127_1632779_1	511062.GU3_00160	7.637e-25	110.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,1SCJD@1236|Gammaproteobacteria,1Y67W@135624|Aeromonadales	135624|Aeromonadales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
LZS2_k127_1632779_3	324602.Caur_0565	1.351e-14	79.0	COG3794@1|root,COG3794@2|Bacteria,2GB9I@200795|Chloroflexi,377MB@32061|Chloroflexia	32061|Chloroflexia	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1632779_0	926550.CLDAP_07210	6.008e-32	128.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cycA	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	Cytochrom_C,Cytochrome_CBB3
LZS2_k127_1632779_4	313603.FB2170_14023	7.84e-07	53.0	2CEFN@1|root,2ZQR3@2|Bacteria,4P7C1@976|Bacteroidetes,1IBIX@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1632779_2	1385514.N782_12390	1.57e-18	95.0	28NT3@1|root,2ZBRV@2|Bacteria,1V1C2@1239|Firmicutes,4HFYQ@91061|Bacilli,2YAMT@289201|Pontibacillus	91061|Bacilli	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
LZS2_k127_1648313_3	1121090.KB894689_gene340	2.479e-21	98.0	COG1414@1|root,COG1414@2|Bacteria,1V5W7@1239|Firmicutes,4HH11@91061|Bacilli,1ZF2F@1386|Bacillus	91061|Bacilli	K	Bacterial transcriptional regulator	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
LZS2_k127_1648313_0	1382356.JQMP01000003_gene2361	1.555e-94	317.0	COG1028@1|root,COG1028@2|Bacteria,2G8P1@200795|Chloroflexi,27XUC@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS2_k127_1648313_4	333138.LQ50_24030	5.866e-12	69.0	COG0500@1|root,COG2226@2|Bacteria,1TY9M@1239|Firmicutes,4I7D5@91061|Bacilli,1ZM4N@1386|Bacillus	91061|Bacilli	Q	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_1648313_1	880073.Calab_2103	3.637e-92	312.0	COG2086@1|root,COG2086@2|Bacteria,2NP4J@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
LZS2_k127_1648313_2	237368.SCABRO_03886	2.417e-27	115.0	2CCSR@1|root,32RWC@2|Bacteria,2J1M5@203682|Planctomycetes	203682|Planctomycetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
LZS2_k127_1657131_5	436114.SYO3AOP1_1722	5.662e-15	77.0	COG1310@1|root,COG1310@2|Bacteria,2G540@200783|Aquificae	200783|Aquificae	S	Mov34 MPN PAD-1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
LZS2_k127_1657131_0	439481.Aboo_0462	6.902e-77	267.0	COG1028@1|root,arCOG01259@2157|Archaea,2XTZX@28890|Euryarchaeota,3F37K@33867|unclassified Euryarchaeota	28890|Euryarchaeota	I	Enoyl-(Acyl carrier protein) reductase	ywfD2	-	1.1.1.100,1.1.1.47	ko:K00034,ko:K00059	ko00030,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00030,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00572	R01520,R01521,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS2_k127_1657131_4	1449080.JQMV01000003_gene1420	9.813e-17	85.0	COG0607@1|root,COG0607@2|Bacteria,1WJ03@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS2_k127_1657131_1	326427.Cagg_3745	2.896e-66	231.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS2_k127_1657131_2	926569.ANT_09090	3.18e-50	192.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G89B@200795|Chloroflexi	200795|Chloroflexi	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBP_BcsQ,Response_reg
LZS2_k127_1657131_3	644966.Tmar_0963	2.781e-39	155.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3WDTC@538999|Clostridiales incertae sedis	186801|Clostridia	U	TIGRFAM signal peptidase I, bacterial type	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
LZS2_k127_1661329_3	502025.Hoch_3843	1.596e-09	60.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,2YUIU@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
LZS2_k127_1661329_0	383372.Rcas_3812	4.457e-149	477.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,376D2@32061|Chloroflexia	32061|Chloroflexia	F	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
LZS2_k127_1661329_2	1034769.KB910518_gene447	3.043e-70	241.0	2DM0V@1|root,318CA@2|Bacteria,1UNMN@1239|Firmicutes,4IUIF@91061|Bacilli,277MU@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1661329_1	670487.Ocepr_0685	2.594e-108	362.0	COG0046@1|root,COG0047@1|root,COG1828@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,COG1828@2|Bacteria,1WIR9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS2_k127_1675188_5	1530186.JQEY01000001_gene893	0.0009163	43.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS2_k127_1675188_4	765420.OSCT_2218	9.753e-27	119.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,2G7J9@200795|Chloroflexi,37522@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,dCache_1
LZS2_k127_1675188_3	306281.AJLK01000019_gene3725	2.732e-34	137.0	COG2944@1|root,COG2944@2|Bacteria,1G6V7@1117|Cyanobacteria	1117|Cyanobacteria	K	helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
LZS2_k127_1675188_1	1499967.BAYZ01000069_gene1904	8.698e-112	374.0	COG1804@1|root,COG1804@2|Bacteria,2NQGI@2323|unclassified Bacteria	2|Bacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS2_k127_1675188_0	926569.ANT_04950	2.426e-168	538.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_1675188_2	485913.Krac_10666	1.631e-97	333.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi	2|Bacteria	E	aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_1712409_3	1283300.ATXB01000001_gene373	2.548e-31	137.0	COG0451@1|root,COG0451@2|Bacteria,1NXWA@1224|Proteobacteria,1RZWF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,SPW,VKOR
LZS2_k127_1712409_2	932678.THERU_04865	1.328e-44	167.0	COG0680@1|root,COG0680@2|Bacteria,2G4B9@200783|Aquificae	200783|Aquificae	C	hydrogenase expression formation protein	hupD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
LZS2_k127_1712409_0	443143.GM18_0459	1.648e-231	725.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hyaL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
LZS2_k127_1712409_4	269799.Gmet_3331	3.5e-25	105.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hyaL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
LZS2_k127_1712409_5	429009.Adeg_1198	4.68e-11	64.0	COG5557@1|root,COG5557@2|Bacteria,1TSZC@1239|Firmicutes,24BX8@186801|Clostridia	186801|Clostridia	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
LZS2_k127_1741511_0	517418.Ctha_0151	3.076e-107	352.0	COG0205@1|root,COG0205@2|Bacteria,1FDFG@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS2_k127_1741511_1	926550.CLDAP_10300	2.298e-91	318.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS2_k127_1762226_4	118168.MC7420_5579	0.0002536	51.0	COG1262@1|root,COG1262@2|Bacteria,1G0ZT@1117|Cyanobacteria,1H92Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS2_k127_1762226_2	1242864.D187_003185	2.083e-54	198.0	COG2815@1|root,COG2815@2|Bacteria,1RIP7@1224|Proteobacteria,42XQG@68525|delta/epsilon subdivisions,2WT9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
LZS2_k127_1762226_3	926569.ANT_03760	9.313e-49	177.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
LZS2_k127_1762226_0	1382356.JQMP01000003_gene1443	2.06e-141	474.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi,27Y1G@189775|Thermomicrobia	189775|Thermomicrobia	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
LZS2_k127_1762226_1	324602.Caur_2611	2.296e-71	275.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,375DF@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
LZS2_k127_1773980_0	479434.Sthe_1523	6.324e-224	701.0	COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi,27XVW@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
LZS2_k127_1773980_1	926569.ANT_17980	3.234e-102	338.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ABC transporter related	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
LZS2_k127_1773980_4	290512.Paes_0724	2.748e-27	116.0	2E3B5@1|root,32YAP@2|Bacteria,1FE8N@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
LZS2_k127_1773980_3	1122919.KB905575_gene3436	6.931e-42	162.0	COG2345@1|root,COG2345@2|Bacteria,1V5Q5@1239|Firmicutes,4HHMX@91061|Bacilli,26U3B@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,HTH_DeoR
LZS2_k127_1773980_2	485913.Krac_8421	1.918e-81	277.0	COG0491@1|root,COG0491@2|Bacteria,2G8CE@200795|Chloroflexi	200795|Chloroflexi	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_1796680_12	926550.CLDAP_32590	2.793e-29	119.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,2G7JP@200795|Chloroflexi	2|Bacteria	K	PFAM AAA-4 family protein	-	-	3.6.4.12	ko:K02444,ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlbA_2,DUF1670,DeoRC,HATPase_c_4,HTH_DeoR
LZS2_k127_1796680_9	59374.Fisuc_1590	2.709e-69	243.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_1796680_3	1232410.KI421428_gene1184	1.291e-147	487.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,43S4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
LZS2_k127_1796680_11	1382306.JNIM01000001_gene325	1.197e-33	139.0	COG0745@1|root,COG0745@2|Bacteria	1382306.JNIM01000001_gene325|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1796680_8	1242864.D187_009121	4.429e-71	253.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
LZS2_k127_1796680_10	396588.Tgr7_0568	3.758e-50	189.0	COG2430@1|root,COG2430@2|Bacteria,1REND@1224|Proteobacteria,1S94F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF432
LZS2_k127_1796680_6	1195246.AGRI_08965	1.796e-101	338.0	COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,1T1Q9@1236|Gammaproteobacteria,465ZP@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	mechanosensitive	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_1796680_15	760568.Desku_2741	3.561e-10	71.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,262CC@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
LZS2_k127_1796680_17	1313172.YM304_41740	6.489e-05	55.0	COG0477@1|root,COG2814@2|Bacteria,2I2DZ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
LZS2_k127_1796680_0	1121104.AQXH01000005_gene189	1.666e-190	612.0	COG0025@1|root,COG0025@2|Bacteria,4PKJ5@976|Bacteroidetes	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
LZS2_k127_1796680_7	926569.ANT_06070	6.508e-80	280.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
LZS2_k127_1796680_13	765420.OSCT_0260	1.504e-20	104.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi,3751W@32061|Chloroflexia	32061|Chloroflexia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS2_k127_1796680_14	926550.CLDAP_39990	1.015e-15	81.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS2_k127_1796680_4	1173026.Glo7428_4776	1.892e-109	359.0	COG3741@1|root,COG3741@2|Bacteria	2|Bacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
LZS2_k127_1796680_2	290512.Paes_0606	3.873e-159	507.0	COG0189@1|root,COG0189@2|Bacteria,1FEIE@1090|Chlorobi	1090|Chlorobi	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
LZS2_k127_1796680_5	926550.CLDAP_05170	1.584e-101	340.0	COG1284@1|root,COG1284@2|Bacteria,2G6SY@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
LZS2_k127_1796680_1	309807.SRU_2257	9.386e-175	567.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,1FJSS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
LZS2_k127_1812163_0	926569.ANT_10380	1.347e-110	379.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
LZS2_k127_1818933_0	357808.RoseRS_2270	8.442e-213	675.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
LZS2_k127_1821671_17	1455608.JDTH01000002_gene1890	8.392e-31	127.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XW2T@28890|Euryarchaeota,23U9Q@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_1821671_13	926550.CLDAP_04760	2.358e-58	211.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
LZS2_k127_1821671_5	1120973.AQXL01000125_gene3179	1.418e-143	467.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,4HDCE@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF2088)	larA	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
LZS2_k127_1821671_6	479434.Sthe_1020	2.112e-129	427.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi,27Y2T@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
LZS2_k127_1821671_14	926550.CLDAP_23630	5.298e-55	200.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_1821671_20	509191.AEDB02000034_gene2223	0.0006995	49.0	COG2730@1|root,COG2730@2|Bacteria,1UTVE@1239|Firmicutes,254HP@186801|Clostridia,3WR4M@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1821671_19	56780.SYN_00516	1.22e-06	61.0	COG1664@1|root,COG1664@2|Bacteria,1MUS9@1224|Proteobacteria,43BNZ@68525|delta/epsilon subdivisions,2X70B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1821671_8	926550.CLDAP_01110	8.413e-123	412.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
LZS2_k127_1821671_18	483219.LILAB_14980	7.128e-12	73.0	COG1357@1|root,COG5635@1|root,COG1357@2|Bacteria,COG5635@2|Bacteria,1N7U9@1224|Proteobacteria,42UJ1@68525|delta/epsilon subdivisions,2WR2I@28221|Deltaproteobacteria,2YU7Z@29|Myxococcales	28221|Deltaproteobacteria	T	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,Pentapeptide
LZS2_k127_1821671_9	357808.RoseRS_2523	1.201e-88	297.0	COG0177@1|root,COG0177@2|Bacteria,2G6A1@200795|Chloroflexi,375YQ@32061|Chloroflexia	32061|Chloroflexia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
LZS2_k127_1821671_4	292459.STH242	4.188e-155	499.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
LZS2_k127_1821671_15	479434.Sthe_1603	1.003e-48	181.0	COG3707@1|root,COG3707@2|Bacteria,2G6CD@200795|Chloroflexi,27XQ5@189775|Thermomicrobia	189775|Thermomicrobia	T	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
LZS2_k127_1821671_2	316274.Haur_3791	7.08e-197	623.0	COG0004@1|root,COG0004@2|Bacteria,2G5N8@200795|Chloroflexi,3753U@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rh family protein ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS2_k127_1821671_1	926569.ANT_13030	6.231e-241	751.0	COG0174@1|root,COG0174@2|Bacteria,2G61M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
LZS2_k127_1821671_16	644282.Deba_0875	7.075e-45	166.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
LZS2_k127_1821671_3	644282.Deba_0876	1.259e-173	553.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS2_k127_1821671_0	344747.PM8797T_21198	0.0	1174.0	COG1391@1|root,COG1391@2|Bacteria,2IXPE@203682|Planctomycetes	203682|Planctomycetes	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	-	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
LZS2_k127_1821671_10	479434.Sthe_2461	5.43e-68	243.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi,27XYH@189775|Thermomicrobia	189775|Thermomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
LZS2_k127_1821671_7	316274.Haur_2249	2.809e-128	424.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi,374UR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_1821671_12	926550.CLDAP_37610	6.874e-60	217.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
LZS2_k127_182678_0	1382356.JQMP01000003_gene1427	2.962e-93	314.0	COG0552@1|root,COG0552@2|Bacteria,2G63M@200795|Chloroflexi,27XH9@189775|Thermomicrobia	189775|Thermomicrobia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
LZS2_k127_182678_2	1125863.JAFN01000001_gene3329	3.377e-24	110.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
LZS2_k127_182678_1	383372.Rcas_1736	6.195e-71	249.0	COG1577@1|root,COG1577@2|Bacteria,2G6DY@200795|Chloroflexi,3763P@32061|Chloroflexia	32061|Chloroflexia	I	PFAM GHMP kinase	-	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS2_k127_1832575_0	926569.ANT_26570	1.015e-123	406.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_1832575_1	926569.ANT_26560	2.036e-92	310.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi	200795|Chloroflexi	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_1832575_2	118173.KB235914_gene316	1.391e-74	267.0	COG3385@1|root,COG3385@2|Bacteria,1G0M7@1117|Cyanobacteria,1HA8V@1150|Oscillatoriales	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
LZS2_k127_1844147_1	926550.CLDAP_29840	3.632e-126	419.0	COG3023@1|root,COG4423@1|root,COG3023@2|Bacteria,COG4423@2|Bacteria	2|Bacteria	S	positive regulation of growth	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	Amidase_2,PG_binding_1,PSK_trans_fac
LZS2_k127_1844147_4	237368.SCABRO_03556	1.108e-49	188.0	COG1357@1|root,COG1357@2|Bacteria,2J0M1@203682|Planctomycetes	203682|Planctomycetes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_1844147_0	771875.Ferpe_0483	1.066e-190	612.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GC1W@200918|Thermotogae	200918|Thermotogae	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	-	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
LZS2_k127_1844147_3	324602.Caur_1997	4.215e-80	271.0	COG3707@1|root,COG3707@2|Bacteria,2G6CD@200795|Chloroflexi,374XC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
LZS2_k127_1844147_2	926550.CLDAP_09730	6.187e-94	327.0	COG3920@1|root,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17	ko:K00936,ko:K02030,ko:K10441,ko:K13924,ko:K20962	ko02010,ko02020,ko02030,ko05111,map02010,map02020,map02030,map05111	M00212,M00236,M00506,M00839	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.3	-	-	GAF,HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12,TPR_8
LZS2_k127_1844147_5	1122917.KB899659_gene5351	3.349e-06	51.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli,26RTF@186822|Paenibacillaceae	91061|Bacilli	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06010	Formyl_trans_C,Formyl_trans_N
LZS2_k127_1845177_0	926569.ANT_29200	4.871e-135	456.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
LZS2_k127_1845177_2	926550.CLDAP_35480	1.057e-08	66.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
LZS2_k127_1845177_1	264732.Moth_1079	3.926e-20	100.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,42F99@68295|Thermoanaerobacterales	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
LZS2_k127_1856279_0	357808.RoseRS_1505	9e-143	460.0	COG2041@1|root,COG2041@2|Bacteria,2G618@200795|Chloroflexi,375BB@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
LZS2_k127_1856279_1	357808.RoseRS_1504	4.467e-61	217.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi,375NC@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
LZS2_k127_1856279_2	1121472.AQWN01000003_gene1525	4.128e-28	120.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,26230@186807|Peptococcaceae	186801|Clostridia	L	pfam nudix	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
LZS2_k127_1856279_3	1317124.DW2_08467	1.727e-08	66.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
LZS2_k127_1858372_0	926550.CLDAP_30420	3.8e-44	174.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
LZS2_k127_1858372_1	1262449.CP6013_1845	4.15e-24	115.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia,36HB5@31979|Clostridiaceae	186801|Clostridia	S	peptidase	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
LZS2_k127_1871451_2	278957.ABEA03000102_gene367	4.267e-99	332.0	COG1387@1|root,COG1387@2|Bacteria,46U67@74201|Verrucomicrobia,3K8DP@414999|Opitutae	414999|Opitutae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
LZS2_k127_1871451_5	1128421.JAGA01000003_gene3490	6.683e-62	218.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
LZS2_k127_1871451_1	1128421.JAGA01000002_gene12	6.047e-103	344.0	COG1131@1|root,COG1131@2|Bacteria,2NPDQ@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_1871451_3	926569.ANT_09930	9.339e-91	317.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
LZS2_k127_1871451_7	63737.Npun_F1117	7.465e-07	57.0	COG1716@1|root,COG1803@1|root,COG1716@2|Bacteria,COG1803@2|Bacteria,1GA4A@1117|Cyanobacteria,1HRYQ@1161|Nostocales	1117|Cyanobacteria	GT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
LZS2_k127_1871451_4	926569.ANT_14180	6.977e-74	270.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
LZS2_k127_1871451_0	1382356.JQMP01000003_gene1858	1.857e-125	407.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
LZS2_k127_1871451_6	926569.ANT_20580	5.591e-33	129.0	COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi	200795|Chloroflexi	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
LZS2_k127_1902218_5	323259.Mhun_2052	7.999e-16	82.0	arCOG06927@1|root,arCOG06927@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1902218_1	1123009.AUID01000007_gene717	2.5e-63	231.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,249TT@186801|Clostridia,269C9@186813|unclassified Clostridiales	186801|Clostridia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_1902218_3	1123288.SOV_6c01030	1.984e-59	220.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H1VG@909932|Negativicutes	909932|Negativicutes	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
LZS2_k127_1902218_4	1117108.PAALTS15_01100	1.189e-17	91.0	COG1309@1|root,COG1309@2|Bacteria,1V63U@1239|Firmicutes,4HHC2@91061|Bacilli,26VHD@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS2_k127_1902218_2	1047013.AQSP01000139_gene2334	5.728e-60	221.0	COG0842@1|root,COG0842@2|Bacteria,2NPA6@2323|unclassified Bacteria	2|Bacteria	V	ABC-type multidrug transport system, permease component	ybhR	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_1902218_0	269799.Gmet_3460	1.277e-64	235.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_1940104_5	311424.DhcVS_1008	9.672e-63	221.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi,34CM3@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
LZS2_k127_1940104_3	765420.OSCT_0996	1.048e-82	288.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi,375DX@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_1940104_2	755731.Clo1100_2795	6.863e-89	300.0	COG3694@1|root,COG3694@2|Bacteria,1V2JQ@1239|Firmicutes,25DJW@186801|Clostridia,36UCG@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
LZS2_k127_1940104_4	1227352.C173_12707	2.293e-63	228.0	COG4587@1|root,COG4587@2|Bacteria,1V4UC@1239|Firmicutes,4HMTT@91061|Bacilli,26WCZ@186822|Paenibacillaceae	91061|Bacilli	S	transport system permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
LZS2_k127_1940104_1	1121121.KB894315_gene1790	1.111e-146	471.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4HEB4@91061|Bacilli,26Q9J@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_1940104_6	933262.AXAM01000074_gene3380	4.437e-43	164.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WNF6@28221|Deltaproteobacteria,2MJZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS2_k127_1940104_8	926569.ANT_27000	5.011e-36	141.0	COG0071@1|root,COG0071@2|Bacteria,2G9EM@200795|Chloroflexi	200795|Chloroflexi	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
LZS2_k127_1940104_7	926569.ANT_27010	4.854e-42	158.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS2_k127_1940104_0	118168.MC7420_1927	6.985e-249	782.0	COG1132@1|root,COG1132@2|Bacteria,1G0EY@1117|Cyanobacteria,1H6XW@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_194096_15	926561.KB900617_gene2286	1.539e-37	158.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,247KG@186801|Clostridia,3WAB7@53433|Halanaerobiales	186801|Clostridia	G	PFAM Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
LZS2_k127_194096_3	28532.XP_010553307.1	1.134e-81	280.0	COG0390@1|root,2RHEJ@2759|Eukaryota,38A5Y@33090|Viridiplantae,3GXSQ@35493|Streptophyta,3HPKC@3699|Brassicales	35493|Streptophyta	S	Aluminum sensitive	-	GO:0003674,GO:0005215,GO:0005338,GO:0005460,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0010035,GO:0010038,GO:0010044,GO:0012506,GO:0015075,GO:0015165,GO:0015711,GO:0015780,GO:0015786,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031090,GO:0031224,GO:0031226,GO:0031982,GO:0034220,GO:0042221,GO:0043226,GO:0043227,GO:0044422,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090481,GO:0098656,GO:1901264,GO:1901505	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
LZS2_k127_194096_4	3885.XP_007160546.1	1.362e-76	263.0	COG1132@1|root,KOG0055@2759|Eukaryota,37J30@33090|Viridiplantae,3GB0T@35493|Streptophyta,4JF51@91835|fabids	35493|Streptophyta	Q	ABC transporter I family member	-	GO:0003674,GO:0005215,GO:0005338,GO:0005460,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0010035,GO:0010038,GO:0010044,GO:0012506,GO:0015075,GO:0015165,GO:0015711,GO:0015780,GO:0015786,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0031090,GO:0031982,GO:0034220,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090481,GO:0098588,GO:0098656,GO:0098805,GO:1901264,GO:1901505	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS2_k127_194096_16	552811.Dehly_0758	5.104e-37	150.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	arcB_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_194096_24	926550.CLDAP_00150	7.931e-08	62.0	COG0664@1|root,COG0664@2|Bacteria,2G902@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_6,Fer4_7,cNMP_binding
LZS2_k127_194096_2	383372.Rcas_2520	4.838e-96	330.0	COG2239@1|root,COG2239@2|Bacteria,2G6H7@200795|Chloroflexi,376RI@32061|Chloroflexia	32061|Chloroflexia	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS2_k127_194096_23	649747.HMPREF0083_02275	8.057e-09	58.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,4HH7Z@91061|Bacilli,26XH1@186822|Paenibacillaceae	91061|Bacilli	O	Peroxiredoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS2_k127_194096_14	1340493.JNIF01000003_gene2665	3.051e-38	145.0	COG1225@1|root,COG1225@2|Bacteria,3Y4Z6@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS2_k127_194096_13	926550.CLDAP_24570	2.069e-38	152.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS2_k127_194096_18	309801.trd_0346	2.34e-24	111.0	COG3815@1|root,COG3815@2|Bacteria,2G73B@200795|Chloroflexi,27Z7M@189775|Thermomicrobia	189775|Thermomicrobia	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
LZS2_k127_194096_22	626887.J057_19075	1.34e-10	66.0	COG0695@1|root,COG0695@2|Bacteria,1NH8Z@1224|Proteobacteria,1SGAT@1236|Gammaproteobacteria,46903@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	XAC3035	-	-	-	-	-	-	-	-	-	-	-	DUF836
LZS2_k127_194096_28	1194165.CAJF01000001_gene2043	0.0003521	51.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
LZS2_k127_194096_19	404380.Gbem_3411	2.497e-24	113.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,43T44@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
LZS2_k127_194096_0	251229.Chro_2918	8.045e-161	515.0	COG0436@1|root,COG0436@2|Bacteria,1GHX7@1117|Cyanobacteria,3VM7E@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS2_k127_194096_7	696281.Desru_2733	3.854e-64	224.0	COG0778@1|root,COG0778@2|Bacteria,1V3YJ@1239|Firmicutes,24MER@186801|Clostridia,266UI@186807|Peptococcaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS2_k127_194096_26	121759.XP_010762154.1	1.553e-06	52.0	COG3670@1|root,KOG1285@2759|Eukaryota,38DX7@33154|Opisthokonta,3NYJJ@4751|Fungi,3QNFB@4890|Ascomycota,20DR9@147545|Eurotiomycetes,3B2AH@33183|Onygenales,3FKP2@34383|Onygenales incertae sedis	4751|Fungi	Q	Retinal pigment epithelial membrane protein	-	-	1.13.11.59	ko:K17842	ko00906,ko01100,map00906,map01100	-	R09782	RC00912,RC01690	ko00000,ko00001,ko01000	-	-	-	RPE65
LZS2_k127_194096_27	439235.Dalk_2131_NEW	0.0002762	46.0	COG3291@1|root,COG3292@1|root,COG3291@2|Bacteria,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,42WTY@68525|delta/epsilon subdivisions,2WSR0@28221|Deltaproteobacteria,2MNQR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PKD,Peptidase_C13,Reg_prop
LZS2_k127_194096_8	926550.CLDAP_20290	1.286e-48	177.0	COG0346@1|root,COG0346@2|Bacteria,2G8UR@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS2_k127_194096_21	926550.CLDAP_00160	2.007e-13	81.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
LZS2_k127_194096_29	1379281.AVAG01000021_gene1080	0.0007402	52.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,2MERM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,SHOCT,zinc_ribbon_2
LZS2_k127_194096_9	1121403.AUCV01000112_gene4554	1.689e-48	182.0	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
LZS2_k127_194096_25	118168.MC7420_4401	3.975e-07	53.0	COG1893@1|root,COG1893@2|Bacteria,1G2H9@1117|Cyanobacteria,1H7Y1@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS2_k127_194096_17	211165.AJLN01000120_gene768	3.531e-36	141.0	COG2402@1|root,COG2402@2|Bacteria,1GKCJ@1117|Cyanobacteria,1JMED@1189|Stigonemataceae	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS2_k127_194096_5	871963.Desdi_1112	8.91e-71	258.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,260UH@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K10681	ko02020,map02020	M00468	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_194096_6	1385514.N782_06795	1.156e-68	239.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,2Y8M2@289201|Pontibacillus	91061|Bacilli	K	PhoP family transcriptional regulator	yycF	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_194096_10	525904.Tter_1733	1.415e-47	180.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
LZS2_k127_194096_12	1408424.JHYI01000011_gene1459	9.939e-39	149.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,4HIKP@91061|Bacilli,1ZH0E@1386|Bacillus	91061|Bacilli	O	Required for disulfide bond formation in some proteins	bdbC	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
LZS2_k127_194096_20	1463895.JODA01000040_gene2348	8.405e-23	108.0	COG0500@1|root,COG2226@2|Bacteria,2IPIZ@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_195091_0	926550.CLDAP_07330	4.421e-187	593.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
LZS2_k127_195091_4	926550.CLDAP_07310	3.176e-38	149.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
LZS2_k127_195091_2	926550.CLDAP_07310	2.897e-108	361.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
LZS2_k127_195091_6	1499967.BAYZ01000048_gene2706	2.094e-21	102.0	COG3616@1|root,COG3616@2|Bacteria,2NPWK@2323|unclassified Bacteria	2|Bacteria	E	Putative serine dehydratase domain	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
LZS2_k127_195091_5	429009.Adeg_0447	7.293e-38	148.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,42GHZ@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM NUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
LZS2_k127_195091_1	118168.MC7420_8020	2.089e-125	408.0	COG1218@1|root,COG1218@2|Bacteria,1G1Z4@1117|Cyanobacteria,1H7F9@1150|Oscillatoriales	1117|Cyanobacteria	P	3'(2'),5'-bisphosphate nucleotidase	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
LZS2_k127_195091_3	926550.CLDAP_29490	6.388e-56	199.0	COG0757@1|root,COG0757@2|Bacteria,2G6N1@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
LZS2_k127_199927_1	1121405.dsmv_1872	1.874e-228	717.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MIMB@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS2_k127_199927_3	1521187.JPIM01000014_gene1795	1.204e-76	264.0	COG2109@1|root,COG2109@2|Bacteria,2G6Q6@200795|Chloroflexi,375GV@32061|Chloroflexia	32061|Chloroflexia	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
LZS2_k127_199927_0	926569.ANT_17020	5.236e-266	834.0	COG1874@1|root,COG1874@2|Bacteria,2G604@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
LZS2_k127_199927_5	926569.ANT_13010	2.678e-09	61.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
LZS2_k127_199927_2	357808.RoseRS_2242	2.848e-215	674.0	COG0477@1|root,COG2814@2|Bacteria,2G71K@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_199927_4	1324957.K933_11936	9.748e-69	239.0	COG0624@1|root,arCOG01107@2157|Archaea,2XU86@28890|Euryarchaeota,23ST7@183963|Halobacteria	183963|Halobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS2_k127_1999435_4	485913.Krac_3313	1.051e-27	115.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi	200795|Chloroflexi	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_1999435_2	1521187.JPIM01000028_gene1595	8.005e-60	217.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_1999435_0	1128421.JAGA01000001_gene2056	7.276e-121	403.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	lisK	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_1999435_1	1128421.JAGA01000001_gene2057	2.827e-95	316.0	COG0745@1|root,COG0745@2|Bacteria,2NQA9@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_1999435_3	357808.RoseRS_3212	3.291e-58	208.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
LZS2_k127_2006457_2	926569.ANT_09730	1.345e-43	168.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi	200795|Chloroflexi	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
LZS2_k127_2006457_0	926569.ANT_09740	1.301e-107	354.0	COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
LZS2_k127_2006457_3	1121430.JMLG01000002_gene993	1.925e-14	76.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,262Q3@186807|Peptococcaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
LZS2_k127_2006457_1	525904.Tter_0060	5.591e-81	282.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
LZS2_k127_2006457_4	1449337.JQLL01000001_gene1482	8.631e-09	57.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli,27FNX@186828|Carnobacteriaceae	91061|Bacilli	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065	6.1.1.24	ko:K09698	ko00970,ko01100,map00970,map01100	M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSB619.SA_RS02860	tRNA-synt_1c
LZS2_k127_2012870_8	1382356.JQMP01000003_gene2053	1.624e-17	87.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,27XXR@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.3.1.13	ko:K15526	-	-	-	-	ko00000,ko01000	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
LZS2_k127_2012870_2	941449.dsx2_0674	4.592e-53	209.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2M7XJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
LZS2_k127_2012870_3	635013.TherJR_1190	7.554e-42	168.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,261JW@186807|Peptococcaceae	186801|Clostridia	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_2012870_5	518766.Rmar_0349	6.338e-31	138.0	COG0697@1|root,COG0697@2|Bacteria,4NP65@976|Bacteroidetes	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_2012870_7	1285586.H131_08413	3.296e-26	123.0	COG1670@1|root,COG1670@2|Bacteria,1V6M5@1239|Firmicutes,4IJQV@91061|Bacilli,3IY29@400634|Lysinibacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
LZS2_k127_2012870_4	926550.CLDAP_18050	1.553e-33	147.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
LZS2_k127_2012870_0	926569.ANT_14490	1.979e-164	529.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria,2G5XD@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
LZS2_k127_2012870_1	926569.ANT_14510	1.999e-125	408.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS2_k127_2033274_3	765420.OSCT_2944	3.066e-48	179.0	2CAZH@1|root,2Z7RU@2|Bacteria,2G8SJ@200795|Chloroflexi,375P9@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
LZS2_k127_2033274_2	1121378.KB899697_gene2847	1.97e-49	202.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
LZS2_k127_2033274_4	1449126.JQKL01000042_gene1034	4.721e-26	126.0	COG3850@1|root,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,HisKA_7TM,MFS_1
LZS2_k127_2033274_1	479434.Sthe_0243	1.134e-68	241.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_2033274_0	1283300.ATXB01000001_gene1229	2.429e-166	567.0	29DE2@1|root,300BX@2|Bacteria,1NC7M@1224|Proteobacteria,1SFWA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2033274_5	56780.SYN_01957	6.375e-06	54.0	COG2041@1|root,COG2041@2|Bacteria,1NS6T@1224|Proteobacteria,42YA7@68525|delta/epsilon subdivisions,2WTM5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2041143_1	179408.Osc7112_0351	1.606e-65	233.0	COG0515@1|root,COG0642@1|root,COG2199@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase,Response_reg
LZS2_k127_2041143_5	240016.ABIZ01000001_gene4604	8.534e-39	150.0	COG0622@1|root,COG0622@2|Bacteria,46XK7@74201|Verrucomicrobia,2IW4A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
LZS2_k127_2041143_6	395495.Lcho_3682	2.331e-27	126.0	COG2908@1|root,COG2908@2|Bacteria,1QZYR@1224|Proteobacteria	1224|Proteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2041143_4	926569.ANT_30470	7.277e-43	172.0	COG1630@1|root,COG1630@2|Bacteria,2G68Z@200795|Chloroflexi	200795|Chloroflexi	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
LZS2_k127_2041143_10	1173263.Syn7502_02457	1.692e-13	78.0	2C7F0@1|root,2Z832@2|Bacteria,1FZVC@1117|Cyanobacteria,1H060@1129|Synechococcus	1117|Cyanobacteria	S	PFAM HAS barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	HAS-barrel
LZS2_k127_2041143_8	756067.MicvaDRAFT_2001	1.29e-21	102.0	COG1357@1|root,COG1357@2|Bacteria,1GD3T@1117|Cyanobacteria,1HEG3@1150|Oscillatoriales	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_2041143_3	756067.MicvaDRAFT_2795	8.994e-47	194.0	COG3447@1|root,COG4191@1|root,COG3447@2|Bacteria,COG4191@2|Bacteria,1G31I@1117|Cyanobacteria,1H9U0@1150|Oscillatoriales	1117|Cyanobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1
LZS2_k127_2041143_9	368407.Memar_1355	2.504e-18	101.0	COG2202@1|root,arCOG02366@1|root,arCOG06536@1|root,arCOG02366@2157|Archaea,arCOG06536@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	ark3	-	2.7.7.72	ko:K00974,ko:K02485	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko02022,ko03016	-	-	-	GAF_2,HATPase_c,HisKA,MCPsignal,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_2041143_0	1499967.BAYZ01000027_gene1810	3.552e-96	349.0	COG2203@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
LZS2_k127_2041143_7	324602.Caur_1173	2.484e-24	111.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
LZS2_k127_2041143_2	1356852.N008_20650	1.296e-49	187.0	COG0668@1|root,COG0668@2|Bacteria,4NEPW@976|Bacteroidetes,47PYQ@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
LZS2_k127_2043891_14	518766.Rmar_0428	0.0004132	44.0	COG4634@1|root,COG4634@2|Bacteria,4NZ31@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2043891_1	926550.CLDAP_24880	1.517e-160	512.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
LZS2_k127_2043891_10	926550.CLDAP_16260	5.059e-52	191.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi	200795|Chloroflexi	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
LZS2_k127_2043891_0	926569.ANT_16100	5.635e-183	585.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
LZS2_k127_2043891_9	1332071.L581_3293	7.371e-83	279.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,401VW@613|Serratia	1236|Gammaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2311,iAPECO1_1312.APECO1_4253,iB21_1397.B21_02196,iBWG_1329.BWG_2085,iE2348C_1286.E2348C_2451,iEC55989_1330.EC55989_2555,iECBD_1354.ECBD_1348,iECB_1328.ECB_02236,iECDH10B_1368.ECDH10B_2473,iECDH1ME8569_1439.ECDH1ME8569_2249,iECD_1391.ECD_02236,iECED1_1282.ECED1_2775,iECH74115_1262.ECH74115_3451,iECIAI39_1322.ECIAI39_2460,iECNA114_1301.ECNA114_2401,iECO103_1326.ECO103_2775,iECOK1_1307.ECOK1_2544,iECP_1309.ECP_2350,iECS88_1305.ECS88_2458,iECSE_1348.ECSE_2620,iECSF_1327.ECSF_2187,iECSP_1301.ECSP_3186,iECs_1301.ECs3195,iETEC_1333.ETEC_2447,iEcDH1_1363.EcDH1_1345,iEcE24377_1341.EcE24377A_2605,iEcHS_1320.EcHS_A2462,iEcSMS35_1347.EcSMS35_2467,iG2583_1286.G2583_2848,iJO1366.b2311,iJR904.b2311,iLF82_1304.LF82_2354,iNRG857_1313.NRG857_11705,iSDY_1059.SDY_2510,iUMN146_1321.UM146_05255,iUMNK88_1353.UMNK88_2862,iUTI89_1310.UTI89_C2595,iY75_1357.Y75_RS12120,iZ_1308.Z3573	Flavoprotein
LZS2_k127_2043891_12	926550.CLDAP_14450	5.161e-42	164.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
LZS2_k127_2043891_8	326427.Cagg_0939	4.951e-96	325.0	COG1089@1|root,COG1089@2|Bacteria,2G6AN@200795|Chloroflexi,3755V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS2_k127_2043891_13	357808.RoseRS_3777	1.54e-40	154.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi,3778H@32061|Chloroflexia	32061|Chloroflexia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
LZS2_k127_2043891_5	926569.ANT_23310	5.457e-109	361.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
LZS2_k127_2043891_3	525904.Tter_1614	1.445e-140	466.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
LZS2_k127_2043891_2	926569.ANT_23340	3.863e-145	475.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_2043891_4	926569.ANT_23350	9.078e-116	381.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
LZS2_k127_2043891_6	926550.CLDAP_38120	4.837e-106	361.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS2_k127_2043891_7	1382306.JNIM01000001_gene36	9.199e-105	353.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
LZS2_k127_2043891_11	357808.RoseRS_3786	7.894e-47	177.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi,374ZS@32061|Chloroflexia	32061|Chloroflexia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
LZS2_k127_2044567_2	1382306.JNIM01000001_gene3883	4.615e-37	142.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi	200795|Chloroflexi	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
LZS2_k127_2044567_0	326427.Cagg_2872	1.392e-287	899.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi,37562@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
LZS2_k127_2044567_4	1185876.BN8_01658	0.0005553	49.0	COG2318@1|root,COG2318@2|Bacteria,4NT5D@976|Bacteroidetes,47VVD@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS2_k127_2044567_1	926569.ANT_23560	1.023e-49	183.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
LZS2_k127_2044567_3	479434.Sthe_1708	4.519e-29	124.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,27Z8D@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
LZS2_k127_2076698_1	1382306.JNIM01000001_gene2807	9.547e-55	198.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi	2|Bacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK3	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
LZS2_k127_2076698_0	1121904.ARBP01000008_gene3419	3.238e-138	445.0	COG3958@1|root,COG3958@2|Bacteria,4NEI8@976|Bacteroidetes,47TCG@768503|Cytophagia	976|Bacteroidetes	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS2_k127_2076698_2	744985.HIMB59_00006570	3.397e-38	146.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,2TRA2@28211|Alphaproteobacteria,4BRX7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	PFAM Transketolase, thiamine diphosphate binding domain	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
LZS2_k127_2078437_1	926550.CLDAP_19630	1.943e-154	499.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS2_k127_2078437_6	316274.Haur_3351	2.659e-46	177.0	COG0340@1|root,COG0340@2|Bacteria,2G6WF@200795|Chloroflexi,375NN@32061|Chloroflexia	32061|Chloroflexia	H	biotin lipoate A B protein ligase	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
LZS2_k127_2078437_0	102129.Lepto7375DRAFT_7626	3.681e-211	699.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,1GPUS@1117|Cyanobacteria,1H9C1@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
LZS2_k127_2078437_5	1521187.JPIM01000131_gene1451	1.773e-52	192.0	COG0537@1|root,COG0537@2|Bacteria,2G6SB@200795|Chloroflexi,377B8@32061|Chloroflexia	32061|Chloroflexia	FG	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
LZS2_k127_2078437_4	1499967.BAYZ01000033_gene1120	2.811e-57	201.0	COG3193@1|root,COG3193@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
LZS2_k127_2078437_3	1382306.JNIM01000001_gene1873	3.351e-72	272.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
LZS2_k127_2078437_2	1047013.AQSP01000122_gene2229	2.98e-116	380.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
LZS2_k127_2238765_0	765420.OSCT_1122	1.929e-234	744.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi,3756S@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS2_k127_2238765_1	548477.HMPREF0294_0380	1.658e-38	155.0	COG1651@1|root,COG1651@2|Bacteria,2IGR9@201174|Actinobacteria,22KGY@1653|Corynebacteriaceae	201174|Actinobacteria	O	DSBA-like thioredoxin domain	dsbA	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
LZS2_k127_2244953_0	221288.JH992901_gene3415	1.828e-96	331.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1JJ8I@1189|Stigonemataceae	1117|Cyanobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
LZS2_k127_2244953_1	99598.Cal7507_1329	7.227e-58	206.0	COG1672@1|root,COG1672@2|Bacteria,1G0F4@1117|Cyanobacteria,1HMJD@1161|Nostocales	1117|Cyanobacteria	K	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,CHAT,TIR_2
LZS2_k127_2246428_4	1123242.JH636435_gene2449	3.485e-27	116.0	COG0561@1|root,COG0561@2|Bacteria,2J04R@203682|Planctomycetes	203682|Planctomycetes	S	Sucrose-6F-phosphate phosphohydrolase	-	-	3.1.3.79	ko:K13086	-	-	R08982	RC00017	ko00000,ko01000	-	-	-	S6PP
LZS2_k127_2246428_1	1122176.KB903537_gene1697	2.99e-189	599.0	COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,1INYH@117747|Sphingobacteriia	976|Bacteroidetes	M	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
LZS2_k127_2246428_2	1313172.YM304_32540	1.506e-95	317.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_18,AAA_33,Hydrolase_like,NTP_transferase,PRK,RNA_lig_T4_1
LZS2_k127_2246428_0	931276.Cspa_c57850	4.997e-242	755.0	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,24AB0@186801|Clostridia,36FBK@31979|Clostridiaceae	186801|Clostridia	G	Sucrose phosphorylase	gtfA	GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758	2.4.1.329,2.4.1.7	ko:K00690,ko:K21350	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
LZS2_k127_2246428_3	1499967.BAYZ01000171_gene5534	1.621e-43	169.0	COG0589@1|root,COG1475@1|root,COG0589@2|Bacteria,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc,Usp
LZS2_k127_2247470_1	1382306.JNIM01000001_gene2513	1.568e-08	56.0	COG2141@1|root,COG2141@2|Bacteria,2G8PY@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS2_k127_2247470_0	926550.CLDAP_27860	4.997e-93	327.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Arylsulfotran_2,Arylsulfotrans
LZS2_k127_2247636_1	926550.CLDAP_07830	1.955e-42	176.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
LZS2_k127_2247636_0	118163.Ple7327_3613	7.493e-54	194.0	COG1047@1|root,COG1047@2|Bacteria,1G5R4@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
LZS2_k127_2247636_2	926550.CLDAP_41040	2.477e-28	122.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_2255520_0	926569.ANT_25420	5.26e-197	623.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
LZS2_k127_2255520_3	326427.Cagg_0770	2.989e-29	121.0	COG1254@1|root,COG1254@2|Bacteria,2G7CV@200795|Chloroflexi,375T9@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
LZS2_k127_2255520_2	926569.ANT_07520	2.473e-36	141.0	COG0640@1|root,COG0640@2|Bacteria,2G78R@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
LZS2_k127_2255520_1	867845.KI911784_gene750	1.674e-143	481.0	COG2217@1|root,COG2217@2|Bacteria,2G5QF@200795|Chloroflexi,376ZJ@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS2_k127_2267074_1	1121929.KB898671_gene4132	1.733e-34	138.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
LZS2_k127_2267074_0	42256.RradSPS_0358	3.801e-193	635.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
LZS2_k127_2270472_2	765420.OSCT_1789	3.299e-134	439.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,374WG@32061|Chloroflexia	32061|Chloroflexia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
LZS2_k127_2270472_7	459349.CLOAM0281	1.933e-72	252.0	COG0289@1|root,COG0289@2|Bacteria,2NPX5@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1520	DapB_C,DapB_N
LZS2_k127_2270472_5	158190.SpiGrapes_0768	3.658e-109	361.0	COG0329@1|root,COG0329@2|Bacteria,2J5J6@203691|Spirochaetes	203691|Spirochaetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS2_k127_2270472_3	1279038.KB907347_gene3153	2.404e-128	418.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,2JQDF@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS2_k127_2270472_0	192952.MM_1885	1.205e-205	646.0	COG0019@1|root,arCOG02268@2157|Archaea,2XSY8@28890|Euryarchaeota,2N93Z@224756|Methanomicrobia	224756|Methanomicrobia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
LZS2_k127_2270472_9	331869.BAL199_22122	1.039e-29	124.0	COG3818@1|root,COG3818@2|Bacteria,1RG7T@1224|Proteobacteria,2U8S8@28211|Alphaproteobacteria,4BSHP@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K06977	-	-	-	-	ko00000	-	-	-	Acetyltransf_1
LZS2_k127_2270472_1	237368.SCABRO_01227	3.706e-186	589.0	COG0436@1|root,COG0436@2|Bacteria,2IX3B@203682|Planctomycetes	203682|Planctomycetes	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_2270472_6	697281.Mahau_1765	4.83e-83	289.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42FIY@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS2_k127_2270472_8	1121335.Clst_0885	6.7e-70	244.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3WIFE@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
LZS2_k127_2270472_10	662479.C440_17076	8.969e-26	117.0	arCOG06181@1|root,arCOG06181@2157|Archaea,2Y06C@28890|Euryarchaeota,23XFD@183963|Halobacteria	183963|Halobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2270472_11	268739.Nmlp_3827	5.154e-18	92.0	arCOG02399@1|root,arCOG02399@2157|Archaea,2XVVI@28890|Euryarchaeota,23UYC@183963|Halobacteria	183963|Halobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
LZS2_k127_2270472_4	118166.JH976537_gene2732	1.003e-123	403.0	28KEA@1|root,2ZA0J@2|Bacteria	2|Bacteria	H	Sulfotransferase	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
LZS2_k127_2272347_5	1128421.JAGA01000003_gene2874	1.391e-63	226.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2272347_7	1128421.JAGA01000003_gene2873	2.049e-57	206.0	COG2010@1|root,COG2010@2|Bacteria,2NPQJ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS2_k127_2272347_8	1128421.JAGA01000003_gene2872	5.406e-56	202.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS2_k127_2272347_2	1128421.JAGA01000003_gene2871	9.273e-194	614.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
LZS2_k127_2272347_0	1128421.JAGA01000003_gene2870	0.0	1142.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
LZS2_k127_2272347_4	1128421.JAGA01000003_gene2869	1.309e-82	280.0	COG3880@1|root,COG3880@2|Bacteria,2NPCX@2323|unclassified Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrome_C7,GSu_C4xC__C2xCH,UVR
LZS2_k127_2272347_1	290512.Paes_0605	6.939e-203	650.0	COG3930@1|root,COG3930@2|Bacteria,1FECR@1090|Chlorobi	1090|Chlorobi	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
LZS2_k127_2272347_3	290512.Paes_0606	1.013e-160	512.0	COG0189@1|root,COG0189@2|Bacteria,1FEIE@1090|Chlorobi	1090|Chlorobi	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
LZS2_k127_2272347_10	331869.BAL199_16798	2.747e-07	55.0	COG2378@1|root,COG2378@2|Bacteria,1PXCX@1224|Proteobacteria,2TTKZ@28211|Alphaproteobacteria,4BSUR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
LZS2_k127_2272347_6	706587.Desti_2090	3.966e-58	207.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
LZS2_k127_2272347_9	1521187.JPIM01000053_gene2946	1.82e-20	97.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
LZS2_k127_2281538_2	321327.CYA_1048	7.985e-32	127.0	COG2154@1|root,COG2154@2|Bacteria,1G7P9@1117|Cyanobacteria,1H11A@1129|Synechococcus	1117|Cyanobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
LZS2_k127_2281538_3	926569.ANT_14650	2.885e-28	119.0	COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
LZS2_k127_2281538_4	485913.Krac_5237	1.587e-25	115.0	COG1011@1|root,COG1011@2|Bacteria,2G787@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS2_k127_2281538_0	1033991.RLEG12_23185	1.302e-131	426.0	COG1735@1|root,COG1735@2|Bacteria,1NPYS@1224|Proteobacteria,2U1F9@28211|Alphaproteobacteria,4BDGK@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Phosphotriesterase family	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
LZS2_k127_2281538_1	290317.Cpha266_1585	2.471e-100	336.0	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	DUF1735,Laminin_G_3,Patatin
LZS2_k127_2281538_5	1131269.AQVV01000024_gene2368	1.162e-24	109.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667	SBP_bac_5
LZS2_k127_2302752_3	502025.Hoch_5646	4.233e-34	132.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WJ61@28221|Deltaproteobacteria,2YZ97@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_2302752_0	398511.BpOF4_11430	1.119e-104	353.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,Sugar_tr
LZS2_k127_2302752_5	379066.GAU_1492	6.602e-27	113.0	COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS2_k127_2302752_2	357808.RoseRS_0521	1.451e-36	152.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi,375CV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2302752_1	1303518.CCALI_01483	3.875e-102	354.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.12,2.7.1.17,2.7.1.5	ko:K00848,ko:K00851,ko:K00854	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
LZS2_k127_2302752_4	926569.ANT_00380	2.56e-28	122.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2302752_6	756272.Plabr_3383	5.89e-20	104.0	28MYQ@1|root,2ZB5K@2|Bacteria,2IZUC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2303043_2	682795.AciX8_4280	6.428e-08	66.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y2Q2@57723|Acidobacteria,2JIEC@204432|Acidobacteriia	204432|Acidobacteriia	KU	WD40-like Beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
LZS2_k127_2303043_0	316274.Haur_4158	1.025e-53	214.0	COG2215@1|root,COG2215@2|Bacteria	2|Bacteria	O	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K08970	-	-	-	-	ko00000,ko02000	2.A.52.2	-	-	DsbD_2,NicO
LZS2_k127_2303043_1	867903.ThesuDRAFT_00284	2.095e-46	171.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,3WDT5@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
LZS2_k127_23148_1	395965.Msil_1523	5.991e-18	84.0	COG0664@1|root,COG0664@2|Bacteria,1NPY0@1224|Proteobacteria,2TT13@28211|Alphaproteobacteria,3NBZR@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	nnrR	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS2_k127_23148_0	264732.Moth_1431	1.399e-101	340.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,42FVC@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS2_k127_2324282_7	316274.Haur_3184	2.788e-32	135.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi,375TV@32061|Chloroflexia	32061|Chloroflexia	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2324282_4	926550.CLDAP_14750	7.271e-78	269.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
LZS2_k127_2324282_2	243164.DET0006	2.817e-126	417.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi,34CWB@301297|Dehalococcoidia	301297|Dehalococcoidia	J	histidyl-tRNA aminoacylation	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
LZS2_k127_2324282_11	1397699.JNIS01000001_gene39	2.797e-11	71.0	COG1051@1|root,COG1051@2|Bacteria,1V5EG@1239|Firmicutes,4HHR4@91061|Bacilli	91061|Bacilli	F	Belongs to the Nudix hydrolase family	nudC_2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_2324282_6	926569.ANT_13310	3.845e-37	154.0	2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi	200795|Chloroflexi	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
LZS2_k127_2324282_10	765420.OSCT_2726	2.129e-19	90.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi,375VD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2324282_8	316274.Haur_4044	3.061e-26	116.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
LZS2_k127_2324282_3	926569.ANT_15140	6.385e-85	299.0	COG0484@1|root,COG2304@1|root,COG0484@2|Bacteria,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi	200795|Chloroflexi	O	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
LZS2_k127_2324282_5	926569.ANT_15150	2.639e-51	193.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS2_k127_2324282_1	926569.ANT_15160	1.454e-181	591.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
LZS2_k127_2324282_9	1121930.AQXG01000005_gene641	7.162e-24	105.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_2324282_0	234267.Acid_3657	4.19e-233	741.0	COG0855@1|root,COG0855@2|Bacteria,3Y2YI@57723|Acidobacteria	57723|Acidobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	-	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
LZS2_k127_2348429_0	1128421.JAGA01000001_gene2352	8.548e-69	244.0	COG0391@1|root,COG0391@2|Bacteria,2NQGV@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0052	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
LZS2_k127_2348429_1	1356852.N008_14225	2.882e-22	99.0	COG0861@1|root,COG0861@2|Bacteria,4NH7P@976|Bacteroidetes,47N45@768503|Cytophagia	976|Bacteroidetes	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
LZS2_k127_2358338_5	1128421.JAGA01000002_gene78	3.982e-22	112.0	COG1928@1|root,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
LZS2_k127_2358338_3	1121451.DESAM_22601	2.359e-56	214.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2M93E@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS2_k127_2358338_2	1121430.JMLG01000002_gene1071	2.104e-113	378.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,26184@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
LZS2_k127_2358338_0	357808.RoseRS_1459	4.535e-236	736.0	COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi,376QX@32061|Chloroflexia	32061|Chloroflexia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_2358338_1	459495.SPLC1_S020090	4.577e-202	644.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1G2KN@1117|Cyanobacteria,1HBXR@1150|Oscillatoriales	1117|Cyanobacteria	EH	Amino-transferase class IV	-	-	2.6.1.85,4.1.3.38	ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
LZS2_k127_2358338_4	264732.Moth_2003	8.052e-50	187.0	COG0740@1|root,COG2068@1|root,COG0740@2|Bacteria,COG2068@2|Bacteria,1TTYG@1239|Firmicutes,25KEI@186801|Clostridia,42IJF@68295|Thermoanaerobacterales	186801|Clostridia	OU	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS2_k127_2359310_4	926550.CLDAP_00150	1.565e-07	64.0	COG0664@1|root,COG0664@2|Bacteria,2G902@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_6,Fer4_7,cNMP_binding
LZS2_k127_2359310_1	479434.Sthe_0625	1.925e-74	256.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi,27Y0R@189775|Thermomicrobia	189775|Thermomicrobia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
LZS2_k127_2359310_5	204669.Acid345_2733	6.992e-05	55.0	COG5617@1|root,COG5617@2|Bacteria,3Y46S@57723|Acidobacteria,2JHJW@204432|Acidobacteriia	204432|Acidobacteriia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
LZS2_k127_2359310_3	357808.RoseRS_0410	1.673e-12	80.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
LZS2_k127_2359310_0	926550.CLDAP_03240	1.448e-92	319.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	-
LZS2_k127_2361387_2	926550.CLDAP_41040	3.078e-69	262.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_2361387_4	1254432.SCE1572_05510	8.576e-30	126.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_2361387_3	926550.CLDAP_07580	8.38e-64	229.0	COG2353@1|root,COG2353@2|Bacteria,2G73S@200795|Chloroflexi	200795|Chloroflexi	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
LZS2_k127_2361387_0	926550.CLDAP_07590	3.509e-151	497.0	COG1368@1|root,COG1368@2|Bacteria	2|Bacteria	M	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS2_k127_2361387_1	1499967.BAYZ01000073_gene2046	1.115e-77	265.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_237239_2	644282.Deba_0869	2.419e-12	70.0	COG1149@1|root,COG1149@2|Bacteria,1QWNA@1224|Proteobacteria,43BT8@68525|delta/epsilon subdivisions,2X73X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
LZS2_k127_237239_1	1408254.T458_12615	1.341e-23	105.0	COG1670@1|root,COG1670@2|Bacteria,1V87J@1239|Firmicutes	1239|Firmicutes	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
LZS2_k127_237239_0	1121403.AUCV01000012_gene4123	1.838e-100	342.0	28K2M@1|root,2Z9RY@2|Bacteria,1R6RC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
LZS2_k127_2376502_6	227882.SAV_5744	4.424e-06	60.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase,TIG
LZS2_k127_2376502_1	671143.DAMO_1946	9.199e-123	424.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
LZS2_k127_2376502_5	903818.KI912268_gene762	5.466e-11	74.0	COG0664@1|root,COG1716@1|root,COG0664@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,cNMP_binding
LZS2_k127_2376502_3	316274.Haur_3068	3.412e-47	179.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	2|Bacteria	KLT	SMART tyrosine protein kinase	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
LZS2_k127_2376502_0	926569.ANT_12740	6.853e-176	561.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi	200795|Chloroflexi	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
LZS2_k127_2376502_4	706587.Desti_4215	4.252e-36	149.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
LZS2_k127_2376502_2	643648.Slip_0683	1.433e-96	325.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia,42KBW@68298|Syntrophomonadaceae	186801|Clostridia	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS2_k127_2390646_17	383372.Rcas_2670	4.816e-17	94.0	COG1306@1|root,COG1306@2|Bacteria,2G81Y@200795|Chloroflexi,374TT@32061|Chloroflexia	32061|Chloroflexia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4015
LZS2_k127_2390646_1	926569.ANT_19080	3.257e-149	485.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS2_k127_2390646_2	926550.CLDAP_05570	9.447e-144	469.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
LZS2_k127_2390646_25	1144275.COCOR_02963	1.471e-07	63.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	actB	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_2390646_26	765420.OSCT_2501	2.149e-07	63.0	COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi,375WU@32061|Chloroflexia	32061|Chloroflexia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2390646_9	765420.OSCT_2500	1.068e-53	195.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_2390646_22	926550.CLDAP_00160	9.001e-13	80.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
LZS2_k127_2390646_18	926550.CLDAP_00160	1.094e-15	88.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
LZS2_k127_2390646_15	248742.XP_005649282.1	5.517e-25	123.0	COG0664@1|root,KOG0614@2759|Eukaryota,KOG1113@2759|Eukaryota,388KC@33090|Viridiplantae,34PAG@3041|Chlorophyta	3041|Chlorophyta	T	Cgmp-dependent protein kinase	CPKG1	-	2.7.11.12	ko:K07376	ko04022,ko04270,ko04540,ko04611,ko04713,ko04714,ko04730,ko04740,ko04923,ko04970,map04022,map04270,map04540,map04611,map04713,map04714,map04730,map04740,map04923,map04970	M00694	-	-	ko00000,ko00001,ko00002,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
LZS2_k127_2390646_8	316274.Haur_3467	1.063e-76	267.0	COG0524@1|root,COG0524@2|Bacteria,2G8C3@200795|Chloroflexi,376T5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS2_k127_2390646_10	926550.CLDAP_10960	1.114e-49	181.0	COG2030@1|root,COG2030@2|Bacteria,2G966@200795|Chloroflexi	200795|Chloroflexi	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
LZS2_k127_2390646_24	383372.Rcas_4165	3.528e-09	68.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2390646_14	485913.Krac_6707	3.564e-29	127.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_2390646_7	926550.CLDAP_23390	4.811e-81	295.0	COG1807@1|root,COG1807@2|Bacteria,2G9BJ@200795|Chloroflexi	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
LZS2_k127_2390646_23	648885.KB316282_gene1441	3.921e-11	75.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,1JT14@119045|Methylobacteriaceae	28211|Alphaproteobacteria	V	PFAM secretion protein HlyD family protein	vceA	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0042221,GO:0046677,GO:0050896,GO:0051716	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
LZS2_k127_2390646_12	479434.Sthe_1865	1.678e-31	131.0	COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia	189775|Thermomicrobia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS2_k127_2390646_0	635013.TherJR_0010	1.259e-154	492.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,25ZYC@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
LZS2_k127_2390646_3	243231.GSU3162	3.293e-137	446.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aromatic amino acid beta-eliminating lyase threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS2_k127_2390646_6	670487.Ocepr_0388	2.606e-100	337.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_2390646_11	272558.10173191	1.477e-33	138.0	COG3467@1|root,COG3467@2|Bacteria,1V62M@1239|Firmicutes,4HH3G@91061|Bacilli,1ZRFB@1386|Bacillus	91061|Bacilli	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
LZS2_k127_2390646_13	632292.Calhy_1954	2.328e-30	132.0	COG1409@1|root,COG1409@2|Bacteria,1VJ4D@1239|Firmicutes	1239|Firmicutes	S	Calcineurin-like phosphoesterase	-	-	3.1.4.17,3.1.4.53	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
LZS2_k127_2390646_5	1382356.JQMP01000003_gene2001	3.697e-108	368.0	COG1167@1|root,COG1167@2|Bacteria,2G5XE@200795|Chloroflexi,27Y0D@189775|Thermomicrobia	189775|Thermomicrobia	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
LZS2_k127_2390646_16	383372.Rcas_4445	2.502e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,375EG@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_2419067_1	686340.Metal_0653	2.517e-59	209.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,1RX1E@1236|Gammaproteobacteria,1XG15@135618|Methylococcales	135618|Methylococcales	IQ	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_2419067_0	1120950.KB892768_gene5306	2.103e-66	233.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria,4DWQP@85009|Propionibacteriales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS2_k127_2419067_4	926569.ANT_01080	7.843e-12	67.0	COG3526@1|root,COG3526@2|Bacteria,2G7F3@200795|Chloroflexi	200795|Chloroflexi	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
LZS2_k127_2419067_2	324602.Caur_1344	3.044e-59	216.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS2_k127_2419067_3	321327.CYA_2481	1.344e-24	110.0	COG3119@1|root,COG3119@2|Bacteria,1G35S@1117|Cyanobacteria,1H28E@1129|Synechococcus	1117|Cyanobacteria	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase,Sulfatase_C
LZS2_k127_2419364_1	1120949.KB903303_gene6680	4.107e-40	157.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria,4DCX9@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS2_k127_2419364_2	1227457.C451_19568	5.281e-08	59.0	COG0286@1|root,arCOG02632@2157|Archaea,2Y0X4@28890|Euryarchaeota,23XY7@183963|Halobacteria	183963|Halobacteria	V	COG0286 Type I restriction-modification system methyltransferase subunit	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
LZS2_k127_2419364_0	926550.CLDAP_12100	2.588e-51	187.0	COG3385@1|root,COG3385@2|Bacteria,2G7UE@200795|Chloroflexi	200795|Chloroflexi	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2426076_1	644966.Tmar_1691	7.441e-73	255.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
LZS2_k127_2426076_2	867845.KI911784_gene1882	3.905e-12	72.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi,375UJ@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
LZS2_k127_2426076_3	446471.Xcel_0024	2.66e-11	69.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,4F3VX@85017|Promicromonosporaceae	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
LZS2_k127_2426076_0	926550.CLDAP_32690	2.099e-129	423.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2G7SW@200795|Chloroflexi	200795|Chloroflexi	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
LZS2_k127_2438794_0	1173264.KI913949_gene106	5.063e-96	338.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
LZS2_k127_2444586_0	1173024.KI912149_gene5025	2.933e-63	243.0	COG1807@1|root,COG1807@2|Bacteria,1G4QV@1117|Cyanobacteria,1JKSA@1189|Stigonemataceae	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_2445812_0	1121878.AUGL01000010_gene1076	2.006e-199	639.0	COG0745@1|root,COG2972@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2972@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1T1YU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K19616	ko02020,map02020	M00771	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CheR,CheR_N,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
LZS2_k127_2455350_11	926569.ANT_17780	2.741e-18	86.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	EAL,GAF_2,GAPES3,GGDEF,PAS_4,PAS_8,PAS_9,RNase_T,SpoIIE,dCache_1
LZS2_k127_2455350_6	926569.ANT_17770	1.479e-70	242.0	COG1905@1|root,COG1905@2|Bacteria,2G6Q5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334,ko:K05586	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
LZS2_k127_2455350_4	926569.ANT_17760	1.869e-80	274.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	AAA_21,AAA_23,AlbA_2,PHP,PHP_C
LZS2_k127_2455350_8	926569.ANT_17750	8.739e-34	133.0	COG4109@1|root,COG4109@2|Bacteria	2|Bacteria	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
LZS2_k127_2455350_3	926569.ANT_17740	2.439e-117	386.0	COG2172@1|root,COG2524@1|root,COG2172@2|Bacteria,COG2524@2|Bacteria,2G9GZ@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
LZS2_k127_2455350_10	1499967.BAYZ01000059_gene4781	2.802e-27	115.0	COG4109@1|root,COG4109@2|Bacteria,2NRFR@2323|unclassified Bacteria	2|Bacteria	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
LZS2_k127_2455350_9	1379698.RBG1_1C00001G0052	5.254e-33	136.0	COG1150@1|root,COG1150@2|Bacteria,2NQ2K@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
LZS2_k127_2455350_5	1379698.RBG1_1C00001G0051	1.575e-76	267.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
LZS2_k127_2455350_0	693661.Arcve_1567	8.313e-257	807.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
LZS2_k127_2455350_7	880073.Calab_3045	1.37e-53	192.0	COG1908@1|root,COG1908@2|Bacteria,2NPFI@2323|unclassified Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	bamF	-	1.8.98.5,1.8.98.6	ko:K14127,ko:K14128	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2083	Fer4,FlpD,HTH_5
LZS2_k127_2455350_2	1379698.RBG1_1C00001G0048	4.388e-119	391.0	COG1941@1|root,COG1941@2|Bacteria,2NQP6@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,FlpD,Oxidored_q6
LZS2_k127_2455350_1	1379698.RBG1_1C00001G0047	4.236e-214	674.0	COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
LZS2_k127_2455350_12	909663.KI867150_gene2060	8.798e-18	87.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WP4D@28221|Deltaproteobacteria,2MQQW@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Hydrogenase maturation protease	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
LZS2_k127_2455376_5	671143.DAMO_0611	3.855e-41	169.0	COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
LZS2_k127_2455376_4	1499967.BAYZ01000182_gene4443	4.534e-82	295.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,2NR1F@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HD_5,HisKA,PAS_4,Response_reg
LZS2_k127_2455376_6	530564.Psta_0804	3.627e-20	96.0	COG0517@1|root,COG0517@2|Bacteria,2J0FD@203682|Planctomycetes	203682|Planctomycetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS2_k127_2455376_0	1123508.JH636440_gene2090	4.188e-235	742.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
LZS2_k127_2455376_1	530564.Psta_0806	4.64e-142	468.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
LZS2_k127_2455376_2	1128421.JAGA01000001_gene2365	2.855e-135	439.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
LZS2_k127_2455376_3	1232437.KL661958_gene2870	1.429e-107	361.0	COG0475@1|root,COG0569@1|root,COG1762@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria,1R9PF@1224|Proteobacteria,42RF1@68525|delta/epsilon subdivisions,2WMJJ@28221|Deltaproteobacteria,2MJ88@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,PTS_EIIA_2,TrkA_C,TrkA_N
LZS2_k127_245913_4	1048339.KB913029_gene833	5.12e-16	79.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria,4ESAK@85013|Frankiales	201174|Actinobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_245913_0	1047013.AQSP01000079_gene2040	1.562e-247	804.0	COG0642@1|root,COG3290@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3292@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3	ko:K07315,ko:K12132,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	FeS,Fe_hyd_lg_C,Fer4,GGDEF,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Y_Y_Y
LZS2_k127_245913_2	1128421.JAGA01000002_gene786	2.587e-87	296.0	COG0024@1|root,COG0024@2|Bacteria,2NP57@2323|unclassified Bacteria	2|Bacteria	J	Methionine aminopeptidase	map	GO:0000096,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006508,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009066,GO:0009987,GO:0010467,GO:0016151,GO:0016485,GO:0016787,GO:0019538,GO:0019752,GO:0030145,GO:0035551,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050897,GO:0051604,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564,GO:1901605	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
LZS2_k127_245913_1	926550.CLDAP_12040	1.023e-157	507.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
LZS2_k127_245913_3	1382306.JNIM01000001_gene684	1.27e-52	192.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS2_k127_245913_5	926550.CLDAP_12350	0.0001715	54.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
LZS2_k127_246399_1	525903.Taci_1436	3.849e-91	302.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,3T9V0@508458|Synergistetes	508458|Synergistetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS2_k127_246399_0	335543.Sfum_2628	1.841e-93	323.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,42MU0@68525|delta/epsilon subdivisions,2WV0U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
LZS2_k127_246399_3	335543.Sfum_2629	2.449e-78	293.0	COG2202@1|root,COG2770@1|root,COG3920@1|root,COG2202@2|Bacteria,COG2770@2|Bacteria,COG3920@2|Bacteria,1NWNJ@1224|Proteobacteria,43BNW@68525|delta/epsilon subdivisions,2X7QA@28221|Deltaproteobacteria,2MRJS@213462|Syntrophobacterales	68525|delta/epsilon subdivisions	T	PFAM ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_246399_2	1499967.BAYZ01000105_gene3479	3.881e-84	310.0	COG0745@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,2NS5N@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
LZS2_k127_2491151_3	525904.Tter_1864	1.374e-39	152.0	COG0391@1|root,COG0391@2|Bacteria,2NQGV@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0052	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
LZS2_k127_2491151_4	479434.Sthe_2612	1.923e-22	105.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi,27YIQ@189775|Thermomicrobia	189775|Thermomicrobia	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
LZS2_k127_2491151_0	552811.Dehly_1197	1.799e-115	383.0	COG4826@1|root,COG4826@2|Bacteria,2GBWN@200795|Chloroflexi,34D50@301297|Dehalococcoidia	301297|Dehalococcoidia	M	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
LZS2_k127_2491151_1	225849.swp_1063	1.7e-79	273.0	COG2220@1|root,COG2220@2|Bacteria,1MVP2@1224|Proteobacteria,1RRSZ@1236|Gammaproteobacteria,2QD0M@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
LZS2_k127_2491151_2	864702.OsccyDRAFT_0951	2.39e-44	166.0	COG3708@1|root,COG3708@2|Bacteria,1GFIV@1117|Cyanobacteria,1HGCM@1150|Oscillatoriales	1117|Cyanobacteria	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2
LZS2_k127_249215_1	926569.ANT_15410	2.05e-137	456.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
LZS2_k127_249215_14	326427.Cagg_0772	2.46e-19	94.0	COG0664@1|root,COG0664@2|Bacteria,2GBTI@200795|Chloroflexi,375RB@32061|Chloroflexia	32061|Chloroflexia	T	PFAM cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
LZS2_k127_249215_9	1319815.HMPREF0202_02144	2.905e-61	222.0	COG1744@1|root,COG1744@2|Bacteria,3796B@32066|Fusobacteria	32066|Fusobacteria	S	basic membrane	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
LZS2_k127_249215_12	926550.CLDAP_22180	1.294e-25	120.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_249215_10	926550.CLDAP_39920	5.858e-53	203.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1929,F5_F8_type_C,Glyco_hyd_65N_2,Glyco_hydro_18,He_PIG,PA14,RCC1,SLH
LZS2_k127_249215_13	1192034.CAP_6472	1.808e-19	102.0	2AHFW@1|root,317T6@2|Bacteria,1PZ6W@1224|Proteobacteria,435S7@68525|delta/epsilon subdivisions,2X070@28221|Deltaproteobacteria,2Z1NY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_249215_0	926550.CLDAP_25270	5.051e-179	571.0	COG1032@1|root,COG1032@2|Bacteria,2G6X0@200795|Chloroflexi	200795|Chloroflexi	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
LZS2_k127_249215_15	911008.GLAD_02793	0.0008134	46.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
LZS2_k127_249215_11	1128421.JAGA01000003_gene3053	4.81e-52	210.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg,dCache_1
LZS2_k127_249215_6	765420.OSCT_0407	8.035e-90	301.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_249215_4	1569209.BBPH01000213_gene1462	1.501e-102	339.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,2PWEK@265|Paracoccus	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
LZS2_k127_249215_7	335543.Sfum_0702	1.642e-87	295.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42NXP@68525|delta/epsilon subdivisions,2WK2A@28221|Deltaproteobacteria,2MRC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS2_k127_249215_2	926569.ANT_02650	4.491e-105	349.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi	2|Bacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS2_k127_249215_3	335543.Sfum_0704	2.162e-104	347.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2MQY5@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS2_k127_249215_5	926569.ANT_02630	6.473e-100	334.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS2_k127_249215_8	765420.OSCT_1170	4.409e-77	267.0	COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like,PBP_like_2
LZS2_k127_249545_0	331678.Cphamn1_1346	0.0	1024.0	COG0433@1|root,COG0433@2|Bacteria,1FEIF@1090|Chlorobi	1090|Chlorobi	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
LZS2_k127_249545_4	671143.DAMO_0371	7.964e-16	85.0	2DP64@1|root,330PH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_249545_1	765420.OSCT_0479	2.397e-91	313.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,3753V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_249545_2	867845.KI911784_gene762	4.986e-74	263.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_249545_3	332101.JIBU02000040_gene1412	4.665e-26	109.0	COG1533@1|root,COG1533@2|Bacteria,1TRIS@1239|Firmicutes,25CEW@186801|Clostridia,36WUR@31979|Clostridiaceae	186801|Clostridia	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_256933_2	316274.Haur_3350	3.081e-44	168.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS2_k127_256933_0	1128421.JAGA01000002_gene1392	4.096e-111	376.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
LZS2_k127_256933_3	1140.Synpcc7942_0099	4.228e-38	145.0	COG1694@1|root,COG1694@2|Bacteria,1G25W@1117|Cyanobacteria,1H41T@1129|Synechococcus	1117|Cyanobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
LZS2_k127_256933_4	1190606.AJYG01000029_gene2978	7.899e-35	141.0	COG3714@1|root,COG3714@2|Bacteria,1PN0I@1224|Proteobacteria,1RNUV@1236|Gammaproteobacteria,1Y26V@135623|Vibrionales	135623|Vibrionales	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
LZS2_k127_256933_1	324057.Pjdr2_3850	1.241e-71	246.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1U3N3@1239|Firmicutes,4HE7D@91061|Bacilli,26RGR@186822|Paenibacillaceae	91061|Bacilli	L	Ribonuclease H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
LZS2_k127_2597992_0	398767.Glov_1587	3.226e-60	239.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
LZS2_k127_2597992_3	56107.Cylst_2503	3.438e-05	51.0	COG1309@1|root,COG1309@2|Bacteria,1G56T@1117|Cyanobacteria,1HJ4K@1161|Nostocales	1117|Cyanobacteria	K	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	TniQ
LZS2_k127_2597992_1	1476583.DEIPH_ctg079orf0035	4.127e-45	174.0	COG3570@1|root,COG3570@2|Bacteria	2|Bacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	str	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
LZS2_k127_2597992_2	926550.CLDAP_05770	4.746e-17	84.0	COG1609@1|root,COG1609@2|Bacteria,2G8NB@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
LZS2_k127_260298_11	324602.Caur_0327	2.153e-34	134.0	COG1917@1|root,COG1917@2|Bacteria,2G7C7@200795|Chloroflexi,377HW@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_260298_9	760568.Desku_3210	1.701e-51	186.0	COG5573@1|root,COG5573@2|Bacteria,1V7GS@1239|Firmicutes,24JFR@186801|Clostridia,2655B@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS2_k127_260298_13	767817.Desgi_2304	5.922e-15	77.0	2E3GV@1|root,32YFJ@2|Bacteria,1VGVF@1239|Firmicutes,24S3F@186801|Clostridia,265KB@186807|Peptococcaceae	186801|Clostridia	L	PFAM CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_260298_2	926550.CLDAP_39140	1.177e-121	400.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_260298_12	1131451.O1K_09102	1.585e-22	105.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1X65S@135614|Xanthomonadales	135614|Xanthomonadales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
LZS2_k127_260298_3	357808.RoseRS_0174	2.399e-117	386.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi,376DK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
LZS2_k127_260298_5	357808.RoseRS_0170	9.15e-84	286.0	COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi,37758@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
LZS2_k127_260298_4	357808.RoseRS_0169	2.905e-102	339.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi,3764I@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
LZS2_k127_260298_0	926569.ANT_12840	4.706e-162	537.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
LZS2_k127_260298_6	459349.CLOAM0931	5.953e-79	270.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
LZS2_k127_260298_7	316274.Haur_4753	1.028e-60	213.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi,375KP@32061|Chloroflexia	32061|Chloroflexia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
LZS2_k127_260298_10	316274.Haur_2516	9.153e-38	149.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi,3774D@32061|Chloroflexia	32061|Chloroflexia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
LZS2_k127_260298_1	1128421.JAGA01000002_gene1037	8.108e-145	472.0	COG0486@1|root,COG0486@2|Bacteria,2NNS4@2323|unclassified Bacteria	2|Bacteria	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
LZS2_k127_260298_8	765420.OSCT_2699	7.645e-54	211.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,2GA9R@200795|Chloroflexi,374ZK@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,dCache_3
LZS2_k127_2614189_1	316274.Haur_0312	5.575e-104	351.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS2_k127_2614189_0	926550.CLDAP_32590	3.021e-150	486.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,2G7JP@200795|Chloroflexi	2|Bacteria	K	PFAM AAA-4 family protein	-	-	3.6.4.12	ko:K02444,ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlbA_2,DUF1670,DeoRC,HATPase_c_4,HTH_DeoR
LZS2_k127_2615335_0	926550.CLDAP_04870	4.236e-285	897.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS2_k127_2615335_1	1122599.AUGR01000010_gene1087	8.808e-05	53.0	COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,1S4CB@1236|Gammaproteobacteria,1XPHR@135619|Oceanospirillales	135619|Oceanospirillales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
LZS2_k127_2630315_0	933262.AXAM01000033_gene1635	4.46e-165	525.0	COG0436@1|root,COG0436@2|Bacteria,1PFZQ@1224|Proteobacteria,431NS@68525|delta/epsilon subdivisions,2WWMZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS2_k127_2630315_1	460265.Mnod_2480	5.965e-09	69.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria,1JXI4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_2645038_0	243164.DET1391	1.946e-121	400.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,34CQM@301297|Dehalococcoidia	301297|Dehalococcoidia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS2_k127_2645038_4	562970.Btus_0044	6.694e-09	62.0	COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,27A34@186823|Alicyclobacillaceae	91061|Bacilli	S	Cyclic-di-AMP receptor	yaaQ	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
LZS2_k127_2645038_3	926569.ANT_04430	2.255e-17	84.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi	200795|Chloroflexi	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
LZS2_k127_2645038_1	926569.ANT_13410	4.023e-117	393.0	COG0477@1|root,COG2814@2|Bacteria,2GBP2@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_2645038_2	235985.BBPN01000033_gene6	6.478e-47	195.0	COG0515@1|root,COG0515@2|Bacteria,2GJTV@201174|Actinobacteria,2NM34@228398|Streptacidiphilus	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4352,Pkinase,TPR_10
LZS2_k127_2653185_2	1499967.BAYZ01000157_gene603	1.751e-38	161.0	COG2203@1|root,COG2208@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	3.1.3.3	ko:K07315,ko:K17763	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,STAS
LZS2_k127_2653185_0	316274.Haur_4694	1.127e-217	682.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,3756A@32061|Chloroflexia	32061|Chloroflexia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS2_k127_2653185_1	1179226.AJXO01000002_gene2189	6.535e-92	316.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli,4GWXI@90964|Staphylococcaceae	91061|Bacilli	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11275	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS2_k127_2674127_1	1121904.ARBP01000006_gene3798	3.003e-45	175.0	2FCEE@1|root,344HX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
LZS2_k127_2674127_0	926569.ANT_15960	6.634e-150	483.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
LZS2_k127_2674127_2	926569.ANT_15980	4.019e-28	121.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_268218_2	1173023.KE650771_gene5241	2.284e-39	169.0	COG2202@1|root,COG2203@1|root,COG2905@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2905@2|Bacteria,COG4251@2|Bacteria,1GHCI@1117|Cyanobacteria,1JMXN@1189|Stigonemataceae	1117|Cyanobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,GAF,GGDEF,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
LZS2_k127_268218_0	316274.Haur_3775	1.075e-53	216.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
LZS2_k127_268218_1	326427.Cagg_3668	3.682e-40	153.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,377BM@32061|Chloroflexia	32061|Chloroflexia	K	Sigma-70, region 4 type 2	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_26912_8	2340.JV46_04680	2.383e-18	88.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,1SCEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Thioredoxin_3
LZS2_k127_26912_5	309801.trd_0666	7.616e-47	175.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,27Y6E@189775|Thermomicrobia	189775|Thermomicrobia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
LZS2_k127_26912_2	926550.CLDAP_25450	4.496e-112	375.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	2|Bacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
LZS2_k127_26912_9	530564.Psta_0723	4.604e-12	74.0	2EJ52@1|root,33CW9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_26912_6	644282.Deba_0464	6.379e-46	170.0	COG0346@1|root,COG0346@2|Bacteria,1NEGB@1224|Proteobacteria	1224|Proteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
LZS2_k127_26912_7	1303518.CCALI_00007	5.936e-20	93.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
LZS2_k127_26912_1	1449126.JQKL01000004_gene620	2.958e-143	466.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2689E@186813|unclassified Clostridiales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
LZS2_k127_26912_10	1121920.AUAU01000003_gene1177	3.173e-09	66.0	2BVWN@1|root,33U5I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_26912_4	871968.DESME_11900	6.063e-48	184.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_26912_3	913325.N799_12410	9.223e-83	279.0	COG1051@1|root,COG1051@2|Bacteria,1N0G9@1224|Proteobacteria,1SIBI@1236|Gammaproteobacteria,1X5ZJ@135614|Xanthomonadales	135614|Xanthomonadales	F	7,8-dihydro-8-oxoguanine-triphosphatase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_26912_0	926569.ANT_10740	1.043e-185	610.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
LZS2_k127_2737354_3	575540.Isop_2314	9.647e-27	123.0	COG0388@1|root,COG0388@2|Bacteria,2J21T@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
LZS2_k127_2737354_0	926569.ANT_06180	5.013e-70	257.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
LZS2_k127_2737354_4	926550.CLDAP_39990	1.284e-15	81.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS2_k127_2737354_2	309801.trd_A0743	5.457e-32	132.0	COG4122@1|root,COG4122@2|Bacteria,2G97D@200795|Chloroflexi,27Y9I@189775|Thermomicrobia	189775|Thermomicrobia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
LZS2_k127_2737354_1	926550.CLDAP_34250	9.992e-41	158.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
LZS2_k127_2762205_1	383372.Rcas_0178	1.156e-116	386.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,374YY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_2762205_0	1521187.JPIM01000047_gene133	2.246e-149	485.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi,375DN@32061|Chloroflexia	32061|Chloroflexia	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS2_k127_2762205_10	1382356.JQMP01000003_gene2048	0.0001291	46.0	COG1647@1|root,COG1647@2|Bacteria,2G909@200795|Chloroflexi,27YHB@189775|Thermomicrobia	189775|Thermomicrobia	S	Serine hydrolase (FSH1)	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
LZS2_k127_2762205_2	926550.CLDAP_20470	5.619e-77	267.0	COG2324@1|root,COG2324@2|Bacteria,2G7BI@200795|Chloroflexi	200795|Chloroflexi	I	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,Caroten_synth
LZS2_k127_2762205_8	1121904.ARBP01000048_gene4107	1.353e-07	59.0	2BVWM@1|root,2ZHCR@2|Bacteria,4P80K@976|Bacteroidetes,47WZS@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2762205_3	526227.Mesil_1491	1.865e-20	98.0	COG1215@1|root,COG1215@2|Bacteria,1WIG8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_2762205_5	1500897.JQNA01000002_gene1522	1.102e-10	65.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VNZQ@28216|Betaproteobacteria,1KGKU@119060|Burkholderiaceae	28216|Betaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
LZS2_k127_2762205_9	105559.Nwat_0421	1.004e-05	51.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	2.6.1.9,3.1.3.10	ko:K00817,ko:K07025,ko:K20866	ko00010,ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01120,ko01130,ko01230,map00010,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01120,map01130,map01230	M00026	R00694,R00734,R00947,R03243	RC00006,RC00078,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	HAD_2,Hydrolase
LZS2_k127_2762205_4	1123278.KB893609_gene4503	1.491e-19	89.0	COG1011@1|root,COG1011@2|Bacteria,4NMJY@976|Bacteroidetes,47X51@768503|Cytophagia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_2762205_7	1121272.KB903251_gene601	2.586e-08	66.0	COG1649@1|root,COG1649@2|Bacteria,2GKNP@201174|Actinobacteria,4DATR@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
LZS2_k127_2762205_6	1123236.KB899379_gene1353	5.186e-10	72.0	COG2304@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,1RPV3@1236|Gammaproteobacteria,46578@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,VWA_2
LZS2_k127_2774493_18	1117318.PRUB_00625	7.977e-05	49.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S0G0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
LZS2_k127_2774493_10	326427.Cagg_2624	1.765e-42	179.0	COG0739@1|root,COG1572@1|root,COG2133@1|root,COG0739@2|Bacteria,COG1572@2|Bacteria,COG2133@2|Bacteria,2G8ZC@200795|Chloroflexi,3759Y@32061|Chloroflexia	32061|Chloroflexia	GM	SMART Animal peptidoglycan recognition protein PGRP	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PA14
LZS2_k127_2774493_6	1333998.M2A_0834	3.769e-86	306.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS2_k127_2774493_14	926550.CLDAP_00160	1.507e-11	75.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
LZS2_k127_2774493_8	309801.trd_1346	1.41e-57	216.0	COG0477@1|root,COG2814@2|Bacteria,2G6MT@200795|Chloroflexi,27YU9@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
LZS2_k127_2774493_2	926560.KE387027_gene1038	6.596e-130	429.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS2_k127_2774493_0	880073.Calab_2950	4.342e-279	866.0	COG0008@1|root,COG0008@2|Bacteria,2NNRW@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECIAI39_1322.ECIAI39_0637	tRNA-synt_1c,tRNA-synt_1c_C
LZS2_k127_2774493_11	485913.Krac_5906	5.041e-33	133.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
LZS2_k127_2774493_12	102232.GLO73106DRAFT_00020600	4.905e-23	107.0	COG0745@1|root,COG0745@2|Bacteria,1G2ME@1117|Cyanobacteria	1117|Cyanobacteria	KT	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_2774493_5	748449.Halha_0131	4.277e-89	312.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WAEA@53433|Halanaerobiales	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
LZS2_k127_2774493_3	156889.Mmc1_2685	1.542e-120	428.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
LZS2_k127_2774493_1	926550.CLDAP_08170	1.152e-152	490.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
LZS2_k127_2774493_9	926550.CLDAP_08160	2.277e-49	186.0	COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi	200795|Chloroflexi	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
LZS2_k127_2774493_15	411489.CLOL250_00170	5.978e-09	63.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
LZS2_k127_2774493_17	395961.Cyan7425_1876	1.013e-06	52.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,3KGVF@43988|Cyanothece	1117|Cyanobacteria	S	ribonuclease BN	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS2_k127_2774493_7	926550.CLDAP_20140	1.047e-72	246.0	COG2193@1|root,COG2193@2|Bacteria,2G6RN@200795|Chloroflexi	200795|Chloroflexi	P	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
LZS2_k127_2774493_4	1303518.CCALI_02921	2.001e-97	335.0	COG0517@1|root,COG1227@1|root,COG0517@2|Bacteria,COG1227@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
LZS2_k127_2774493_13	660470.Theba_0222	7.099e-13	77.0	COG1470@1|root,COG3291@1|root,COG1470@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM,NPCBM_assoc,PEGA
LZS2_k127_2830037_5	948106.AWZT01000002_gene6423	1.582e-09	59.0	COG1879@1|root,COG1879@2|Bacteria,1MU95@1224|Proteobacteria,2VU4J@28216|Betaproteobacteria,1K0D8@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
LZS2_k127_2830037_3	1122915.AUGY01000011_gene3989	1.979e-23	105.0	2EGE1@1|root,33A5Y@2|Bacteria,1VV4C@1239|Firmicutes,4HVGE@91061|Bacilli,26YKG@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2830037_4	1347086.CCBA010000027_gene3325	8.126e-23	100.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4HNVM@91061|Bacilli,1ZJ56@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	lanR	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
LZS2_k127_2830037_1	479432.Sros_0608	1.628e-94	315.0	COG5395@1|root,COG5395@2|Bacteria,2IHVI@201174|Actinobacteria,4EJNA@85012|Streptosporangiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
LZS2_k127_2830037_0	574375.BAGA_10105	3.838e-125	408.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
LZS2_k127_2830037_2	911045.PSE_1283	6.689e-48	180.0	28IZQ@1|root,2Z8X1@2|Bacteria,1R7RF@1224|Proteobacteria,2UJ99@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
LZS2_k127_2830037_6	1122622.ATWJ01000007_gene1705	0.0002223	43.0	COG3544@1|root,COG3544@2|Bacteria,2IFX2@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
LZS2_k127_2852954_8	118168.MC7420_7118	1.513e-72	250.0	COG3568@1|root,COG3568@2|Bacteria,1G3AW@1117|Cyanobacteria,1HG54@1150|Oscillatoriales	1117|Cyanobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2,DUF504,Exo_endo_phos,PAP_central
LZS2_k127_2852954_19	47839.CCAU010000011_gene5833	3.678e-23	117.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,SIR2_2,Trypsin_2
LZS2_k127_2852954_11	330214.NIDE4175	1.426e-47	194.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS2_k127_2852954_9	485913.Krac_0962	1.317e-66	252.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
LZS2_k127_2852954_14	1114922.CIFAM_17_01930	1.363e-40	162.0	COG2227@1|root,COG2519@1|root,COG2227@2|Bacteria,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,1RSIH@1236|Gammaproteobacteria,3WWXF@544|Citrobacter	1236|Gammaproteobacteria	HJ	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
LZS2_k127_2852954_7	272134.KB731324_gene6257	3.886e-74	256.0	COG1451@1|root,COG1451@2|Bacteria,1G6GG@1117|Cyanobacteria,1HB3P@1150|Oscillatoriales	1117|Cyanobacteria	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
LZS2_k127_2852954_12	670487.Ocepr_1315	8.268e-46	170.0	COG2236@1|root,COG2236@2|Bacteria,1WJRW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
LZS2_k127_2852954_18	1123250.KB908391_gene310	1.104e-30	130.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4H4Z4@909932|Negativicutes	909932|Negativicutes	L	ComEA protein	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
LZS2_k127_2852954_1	1382306.JNIM01000001_gene1224	2.257e-276	872.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
LZS2_k127_2852954_16	588932.JHOF01000003_gene2556	3.67e-35	138.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,2KGVB@204458|Caulobacterales	204458|Caulobacterales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
LZS2_k127_2852954_17	862517.HMPREF9225_1889	1.091e-31	130.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,22HI4@1570339|Peptoniphilaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
LZS2_k127_2852954_5	479434.Sthe_1606	4.22e-82	280.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi,27XYK@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
LZS2_k127_2852954_10	1230341.MJ3_13189	6.18e-61	213.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
LZS2_k127_2852954_6	316274.Haur_0121	2.353e-77	268.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,37569@32061|Chloroflexia	32061|Chloroflexia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
LZS2_k127_2852954_21	1121445.ATUZ01000013_gene1020	1.343e-08	60.0	COG0690@1|root,COG0690@2|Bacteria,1Q1BI@1224|Proteobacteria,42X4Z@68525|delta/epsilon subdivisions,2WSQ8@28221|Deltaproteobacteria,2MD79@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
LZS2_k127_2852954_20	926569.ANT_19010	1.435e-19	88.0	COG0267@1|root,COG0267@2|Bacteria,2G7GT@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
LZS2_k127_2852954_2	926550.CLDAP_14800	1.971e-215	673.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi	200795|Chloroflexi	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS2_k127_2852954_3	671143.DAMO_2604	2.18e-184	596.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS2_k127_2852954_15	926569.ANT_19290	1.104e-35	145.0	2EV3Q@1|root,33NIR@2|Bacteria,2G9SC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2852954_4	485916.Dtox_3935	1.05e-92	310.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
LZS2_k127_2852954_0	926569.ANT_04140	0.0	1107.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS2_k127_2852954_13	1173027.Mic7113_6282	5.351e-45	176.0	COG1357@1|root,COG1357@2|Bacteria,1G4NS@1117|Cyanobacteria,1H7EA@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM pentapeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_2852954_22	926550.CLDAP_12370	2.131e-08	61.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2861833_0	2711.XP_006475328.1	1.092e-57	205.0	COG4992@1|root,KOG1401@2759|Eukaryota,37JRF@33090|Viridiplantae,3GBNS@35493|Streptophyta	35493|Streptophyta	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.6.1.11	ko:K00818	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02283	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_2861833_5	138119.DSY1929	9.645e-34	137.0	COG1246@1|root,COG1246@2|Bacteria,1V6TZ@1239|Firmicutes,24KQF@186801|Clostridia,2626A@186807|Peptococcaceae	186801|Clostridia	E	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
LZS2_k127_2861833_1	1536772.R70723_27805	8.071e-54	194.0	COG0454@1|root,COG0456@2|Bacteria,1V81Z@1239|Firmicutes,4HIXF@91061|Bacilli,275IW@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
LZS2_k127_2861833_3	1444712.BN1013_01006	1.572e-44	167.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	yokL3	-	2.3.1.57	ko:K00657,ko:K07023	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
LZS2_k127_2861833_4	717606.PaecuDRAFT_0199	9.896e-39	150.0	COG0454@1|root,COG0456@2|Bacteria,1V3VH@1239|Firmicutes,4I8AM@91061|Bacilli,26ZF6@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_2861833_2	1304885.AUEY01000083_gene2532	5.157e-49	179.0	COG0454@1|root,COG0456@2|Bacteria,1RA6D@1224|Proteobacteria,42TYF@68525|delta/epsilon subdivisions,2WQQZ@28221|Deltaproteobacteria,2MKJ0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_2865295_0	797209.ZOD2009_21577	1.949e-187	612.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria	183963|Halobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2,Usp
LZS2_k127_2865295_1	1121382.JQKG01000063_gene3034	2.021e-101	341.0	COG1879@1|root,COG1879@2|Bacteria,1WK3A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439,ko:K10549	ko02010,ko02030,map02010,map02030	M00212,M00217	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.6	-	-	Peripla_BP_4
LZS2_k127_2865295_2	1121382.JQKG01000063_gene3032	7.267e-98	331.0	COG1172@1|root,COG1172@2|Bacteria,1WK1K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	COGs COG1172 Ribose xylose arabinose galactoside ABC-type transport systems permease components	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
LZS2_k127_2865295_3	926550.CLDAP_06170	1.391e-16	80.0	COG1129@1|root,COG1129@2|Bacteria,2G8AK@200795|Chloroflexi	200795|Chloroflexi	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
LZS2_k127_2868754_3	357808.RoseRS_3334	7.001e-69	240.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,374TE@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
LZS2_k127_2868754_0	1128421.JAGA01000001_gene2444	2.212e-170	551.0	COG2317@1|root,COG2317@2|Bacteria,2NQC7@2323|unclassified Bacteria	2|Bacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	ypwA	-	3.4.17.19	ko:K01299,ko:K03281	-	-	-	-	ko00000,ko01000,ko01002	2.A.49	-	-	Peptidase_M32
LZS2_k127_2868754_2	926569.ANT_17250	1.576e-110	365.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	200795|Chloroflexi	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS2_k127_2868754_1	1121430.JMLG01000030_gene1612	2.366e-153	499.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,260G0@186807|Peptococcaceae	186801|Clostridia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
LZS2_k127_2893406_17	1158607.UAU_02420	0.0004026	45.0	COG1376@1|root,COG1376@2|Bacteria,1V4KP@1239|Firmicutes,4HIBF@91061|Bacilli,4B3BZ@81852|Enterococcaceae	91061|Bacilli	S	L,D-transpeptidase catalytic domain	yciB	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS2_k127_2893406_12	33898.JRHJ01000069_gene7064	2.288e-27	125.0	COG3103@1|root,COG3103@2|Bacteria,2I3C9@201174|Actinobacteria	201174|Actinobacteria	T	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
LZS2_k127_2893406_14	402777.KB235904_gene3527	1.779e-20	101.0	COG0251@1|root,COG1357@1|root,COG0251@2|Bacteria,COG1357@2|Bacteria,1G6TD@1117|Cyanobacteria,1H9XQ@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Pentapeptide,Ribonuc_L-PSP
LZS2_k127_2893406_11	192952.MM_3241	8.03e-34	140.0	COG3247@1|root,arCOG03582@2157|Archaea,2Y5FW@28890|Euryarchaeota,2NBDS@224756|Methanomicrobia	224756|Methanomicrobia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
LZS2_k127_2893406_7	926550.CLDAP_01500	2.061e-60	226.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS2_k127_2893406_4	1134413.ANNK01000111_gene1552	1.909e-97	323.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus	91061|Bacilli	P	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
LZS2_k127_2893406_13	388467.A19Y_1879	2.827e-22	109.0	COG4803@1|root,COG4803@2|Bacteria,1GA6S@1117|Cyanobacteria,1HEWV@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
LZS2_k127_2893406_9	497965.Cyan7822_4760	2.108e-45	179.0	COG3861@1|root,COG3861@2|Bacteria,1GM7B@1117|Cyanobacteria,3KJPH@43988|Cyanothece	1117|Cyanobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2893406_15	118173.KB235914_gene2492	7.471e-17	87.0	COG4803@1|root,COG4803@2|Bacteria,1G531@1117|Cyanobacteria,1HB6E@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
LZS2_k127_2893406_16	429009.Adeg_1040	1.255e-09	63.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,42FVJ@68295|Thermoanaerobacterales	186801|Clostridia	D	ATPase MipZ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
LZS2_k127_2893406_8	926550.CLDAP_21020	1.066e-58	211.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_2893406_5	926550.CLDAP_21010	6.175e-87	326.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
LZS2_k127_2893406_6	330214.NIDE0585	1.486e-69	270.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
LZS2_k127_2893406_10	879212.DespoDRAFT_01392	2.966e-43	162.0	COG1371@1|root,COG1371@2|Bacteria,1NCP6@1224|Proteobacteria,42VQE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM Archease protein family (DUF101 UPF0211)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
LZS2_k127_2893406_0	879212.DespoDRAFT_01391	9.521e-253	787.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2MHPF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
LZS2_k127_2893406_2	1304888.ATWF01000001_gene1816	1.793e-129	425.0	COG1092@1|root,COG1092@2|Bacteria,2GFN8@200930|Deferribacteres	200930|Deferribacteres	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
LZS2_k127_2893406_1	255470.cbdbA1613	5.052e-245	768.0	COG1032@1|root,COG1032@2|Bacteria,2GAMN@200795|Chloroflexi,34CSR@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Radical SAM N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_N
LZS2_k127_2893406_3	1232410.KI421428_gene1038	2.238e-111	374.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43T9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
LZS2_k127_2895231_0	926569.ANT_20830	4.742e-67	241.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS2_k127_2898144_1	357808.RoseRS_1707	6.522e-150	484.0	COG0701@1|root,COG0701@2|Bacteria,2G6DW@200795|Chloroflexi,376WA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
LZS2_k127_2898144_3	479434.Sthe_1375	1.883e-29	122.0	COG0640@1|root,COG0640@2|Bacteria,2G7FZ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
LZS2_k127_2898144_2	118163.Ple7327_3613	2.686e-40	153.0	COG1047@1|root,COG1047@2|Bacteria,1G5R4@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
LZS2_k127_2898144_0	926560.KE387023_gene1701	6.11e-202	651.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_2901496_0	926550.CLDAP_32470	7.296e-47	186.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_2901496_1	357808.RoseRS_1784	1.184e-17	87.0	COG5305@1|root,COG5305@2|Bacteria,2GAHI@200795|Chloroflexi,3765S@32061|Chloroflexia	32061|Chloroflexia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_290471_0	926550.CLDAP_31220	5.801e-97	338.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
LZS2_k127_290471_2	755178.Cyan10605_2360	7.44e-34	136.0	COG1943@1|root,COG1943@2|Bacteria,1G5AE@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS2_k127_290471_3	765420.OSCT_1229	5.979e-29	123.0	COG0745@1|root,COG0745@2|Bacteria	765420.OSCT_1229|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_290471_1	926550.CLDAP_03240	7.145e-35	145.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	-
LZS2_k127_2917678_0	926550.CLDAP_11790	3.34e-106	355.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
LZS2_k127_2917678_1	926550.CLDAP_11780	3.327e-49	179.0	COG1215@1|root,COG1215@2|Bacteria,2GBNZ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS2_k127_2948248_0	926569.ANT_15930	1.747e-95	321.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
LZS2_k127_2948248_1	479434.Sthe_1208	7.258e-77	263.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,27XW2@189775|Thermomicrobia	189775|Thermomicrobia	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
LZS2_k127_2960930_0	573413.Spirs_3975	0.0	1018.0	COG0209@1|root,COG0209@2|Bacteria,2J5M3@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
LZS2_k127_2960930_2	1095770.CAHE01000024_gene334	4.481e-41	156.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,22HHT@1570339|Peptoniphilaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
LZS2_k127_2960930_1	255470.cbdbA928	3.64e-227	728.0	COG0514@1|root,COG1205@1|root,COG0514@2|Bacteria,COG1205@2|Bacteria,2G605@200795|Chloroflexi,34CMG@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
LZS2_k127_3020808_2	926550.CLDAP_12370	1.679e-29	124.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3020808_0	926550.CLDAP_12360	1.046e-147	486.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350,ko:K21000	ko00460,ko00500,ko00940,ko01100,ko01110,ko02025,map00460,map00500,map00940,map01100,map01110,map02025	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH39	-	Cellulase,Glyco_hydro_1
LZS2_k127_3020808_1	1232437.KL662043_gene2232	5.069e-64	223.0	COG1853@1|root,COG1853@2|Bacteria,1RAIQ@1224|Proteobacteria,43EWA@68525|delta/epsilon subdivisions,2X2AG@28221|Deltaproteobacteria,2MME7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM flavin reductase domain protein FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
LZS2_k127_3050671_1	867845.KI911784_gene1941	1.191e-77	276.0	COG0545@1|root,COG0545@2|Bacteria,2GA7H@200795|Chloroflexi,3762K@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidylprolyl isomerase FKBP-type	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
LZS2_k127_3050671_2	980584.AFPB01000176_gene1786	8.81e-30	134.0	COG0545@1|root,COG0652@1|root,COG0545@2|Bacteria,COG0652@2|Bacteria,4NDW4@976|Bacteroidetes,1HYBT@117743|Flavobacteriia,405WH@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	O	FKBP-type peptidyl-prolyl cis-trans isomerase	ppiC	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03772	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	FKBP_C,Pro_isomerase
LZS2_k127_3050671_0	926569.ANT_05230	2.482e-233	737.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
LZS2_k127_3089643_3	247633.GP2143_17696	1.255e-30	123.0	2E7GG@1|root,331Z9@2|Bacteria	2|Bacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
LZS2_k127_3089643_4	529818.AMSG_09240T0	2.04e-21	99.0	2D0EA@1|root,2SDWH@2759|Eukaryota	2759|Eukaryota	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
LZS2_k127_3089643_0	1120950.KB892757_gene6492	1.426e-269	848.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DP2R@85009|Propionibacteriales	201174|Actinobacteria	EG	Dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
LZS2_k127_3089643_2	479434.Sthe_2909	2.269e-52	190.0	COG1012@1|root,COG1012@2|Bacteria,2G7YU@200795|Chloroflexi,27Y0H@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
LZS2_k127_3095032_0	1304885.AUEY01000104_gene2548	6.285e-123	401.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
LZS2_k127_3098684_2	926569.ANT_11480	3.145e-84	293.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_3098684_3	926550.CLDAP_00870	1.128e-82	280.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_3098684_0	926550.CLDAP_00880	8.334e-150	482.0	COG0438@1|root,COG0438@2|Bacteria,2G7QG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_3098684_4	1382306.JNIM01000001_gene4122	1.372e-35	145.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
LZS2_k127_3098684_1	326427.Cagg_2193	1.01e-113	374.0	COG1175@1|root,COG1175@2|Bacteria,2G6P7@200795|Chloroflexi,376BI@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
LZS2_k127_3098684_5	357808.RoseRS_4567	1.739e-24	106.0	COG0395@1|root,COG0395@2|Bacteria,2G6H2@200795|Chloroflexi,376ZC@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
LZS2_k127_3101000_5	6669.EFX89115	9.765e-09	68.0	COG1524@1|root,KOG2126@2759|Eukaryota,38C76@33154|Opisthokonta,3BG4T@33208|Metazoa,3D0JG@33213|Bilateria,41UW1@6656|Arthropoda	33208|Metazoa	T	catalytic activity. It is involved in the biological process described with metabolic process	PIGO	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006497,GO:0006505,GO:0006506,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006661,GO:0006664,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009247,GO:0009987,GO:0012505,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019538,GO:0019637,GO:0031984,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045017,GO:0046467,GO:0046474,GO:0046486,GO:0046488,GO:0051377,GO:0071704,GO:0090407,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	-	ko:K05288	ko00563,ko01100,map00563,map01100	-	R05923,R08107	RC00017	ko00000,ko00001	-	-	-	Phosphodiest
LZS2_k127_3101000_4	1128421.JAGA01000004_gene2480	6.589e-52	193.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
LZS2_k127_3101000_0	1121403.AUCV01000023_gene3381	0.0	1003.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,43AEI@68525|delta/epsilon subdivisions,2X5UC@28221|Deltaproteobacteria,2MPH6@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Alpha amylase, C-terminal all-beta domain	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
LZS2_k127_3101000_2	1391647.AVSV01000038_gene729	2.09e-67	233.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,36HZI@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
LZS2_k127_3101000_6	67373.JOBF01000031_gene2906	7.824e-07	61.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_3101000_3	123214.PERMA_1580	9.488e-59	220.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
LZS2_k127_3101000_1	926550.CLDAP_04380	9.138e-80	272.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
LZS2_k127_3109958_1	670292.JH26_09630	1.751e-05	57.0	COG1652@1|root,COG1652@2|Bacteria,1RCB6@1224|Proteobacteria,2U5WG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Gmad2,LysM
LZS2_k127_3109958_2	1504319.GM45_0750	0.0006972	44.0	COG2270@1|root,COG2270@2|Bacteria,2GJCW@201174|Actinobacteria,3UWX4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
LZS2_k127_3130756_4	400682.PAC_15705797	3.935e-88	293.0	COG0050@1|root,KOG0460@2759|Eukaryota,38BHM@33154|Opisthokonta,3BE5J@33208|Metazoa	33208|Metazoa	J	translation elongation factor activity	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS2_k127_3130756_20	926550.CLDAP_04110	4.404e-49	177.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi	200795|Chloroflexi	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
LZS2_k127_3130756_9	469371.Tbis_0562	5.453e-73	251.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4DZ30@85010|Pseudonocardiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
LZS2_k127_3130756_13	316274.Haur_4916	3.472e-60	214.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi,374Y7@32061|Chloroflexia	32061|Chloroflexia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
LZS2_k127_3130756_31	891968.Anamo_0476	6.209e-16	81.0	COG0089@1|root,COG0089@2|Bacteria,3TBBG@508458|Synergistetes	508458|Synergistetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
LZS2_k127_3130756_1	926550.CLDAP_04070	1.558e-136	438.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
LZS2_k127_3130756_22	926569.ANT_10080	1.403e-42	156.0	COG0185@1|root,COG0185@2|Bacteria,2G6US@200795|Chloroflexi	200795|Chloroflexi	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
LZS2_k127_3130756_26	446470.Snas_1190	5.299e-29	119.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4EYPP@85014|Glycomycetales	201174|Actinobacteria	J	Ribosomal protein L22p/L17e	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
LZS2_k127_3130756_7	926550.CLDAP_04040	8.366e-78	266.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi	200795|Chloroflexi	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
LZS2_k127_3130756_12	555088.DealDRAFT_1516	2.78e-64	222.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,42JV4@68298|Syntrophomonadaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
LZS2_k127_3130756_33	1278311.AUAL01000019_gene634	3.325e-12	68.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
LZS2_k127_3130756_28	857293.CAAU_1218	3.064e-26	109.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,36KIV@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
LZS2_k127_3130756_16	479434.Sthe_1046	2.014e-54	193.0	COG0093@1|root,COG0093@2|Bacteria,2G6MZ@200795|Chloroflexi,27YG0@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
LZS2_k127_3130756_29	926569.ANT_10150	9.949e-26	110.0	COG0198@1|root,COG0198@2|Bacteria,2G750@200795|Chloroflexi	200795|Chloroflexi	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
LZS2_k127_3130756_6	926550.CLDAP_03980	3.694e-83	278.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi	200795|Chloroflexi	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
LZS2_k127_3130756_27	926569.ANT_10170	1.016e-26	109.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi	200795|Chloroflexi	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
LZS2_k127_3130756_21	926569.ANT_10180	2.295e-46	170.0	COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
LZS2_k127_3130756_11	1392502.JNIO01000002_gene118	2.135e-65	228.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4H78Z@909932|Negativicutes	909932|Negativicutes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
LZS2_k127_3130756_23	888746.HMPREF9180_0077	2.052e-38	149.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
LZS2_k127_3130756_10	926550.CLDAP_03930	4.465e-66	229.0	COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi	200795|Chloroflexi	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
LZS2_k127_3130756_30	926569.ANT_10220	2.456e-16	79.0	COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
LZS2_k127_3130756_18	273068.TTE2273	2.122e-50	183.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
LZS2_k127_3130756_0	525904.Tter_0735	6.982e-143	465.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
LZS2_k127_3130756_3	562970.Btus_0175	2.635e-91	307.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,277XD@186823|Alicyclobacillaceae	91061|Bacilli	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
LZS2_k127_3130756_32	1203605.HMPREF1531_00148	1.013e-13	71.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
LZS2_k127_3130756_17	926550.CLDAP_03860	1.341e-53	190.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
LZS2_k127_3130756_19	479434.Sthe_1062	1.608e-49	179.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi,27YAA@189775|Thermomicrobia	189775|Thermomicrobia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
LZS2_k127_3130756_5	926550.CLDAP_03840	7.126e-85	286.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
LZS2_k127_3130756_2	926550.CLDAP_03830	2.479e-131	426.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
LZS2_k127_3130756_25	671143.DAMO_0567	1.723e-35	138.0	COG0203@1|root,COG0203@2|Bacteria,2NPYQ@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879,ko:K16193	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
LZS2_k127_3130756_15	358681.BBR47_02530	1.903e-56	206.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,26SXM@186822|Paenibacillaceae	91061|Bacilli	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
LZS2_k127_3130756_14	443254.Marpi_1669	7.093e-60	210.0	COG0102@1|root,COG0102@2|Bacteria,2GD15@200918|Thermotogae	200918|Thermotogae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
LZS2_k127_3130756_24	926550.CLDAP_03790	6.367e-38	146.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS2_k127_3130756_8	1200792.AKYF01000020_gene4917	8.859e-74	256.0	COG0454@1|root,COG0454@2|Bacteria,1UJQZ@1239|Firmicutes,4ITDK@91061|Bacilli	91061|Bacilli	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
LZS2_k127_3135558_1	926550.CLDAP_01230	9.827e-24	111.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
LZS2_k127_3135558_0	1121448.DGI_2179	1.017e-25	112.0	COG0454@1|root,COG0456@2|Bacteria,1N6E5@1224|Proteobacteria,42UYS@68525|delta/epsilon subdivisions,2WQS5@28221|Deltaproteobacteria,2MCIW@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS2_k127_3135558_2	1379698.RBG1_1C00001G1207	1.194e-18	101.0	COG1807@1|root,COG3063@1|root,COG1807@2|Bacteria,COG3063@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_16,TPR_8
LZS2_k127_3149296_1	1379698.RBG1_1C00001G0419	7.313e-31	123.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_3149296_2	926569.ANT_23520	2.592e-29	127.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
LZS2_k127_3149296_0	1444309.JAQG01000004_gene3580	2.042e-47	179.0	COG3375@1|root,COG3375@2|Bacteria,1V21D@1239|Firmicutes,4HG3H@91061|Bacilli,272FA@186822|Paenibacillaceae	91061|Bacilli	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_3165471_2	926550.CLDAP_29120	1.507e-90	299.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_3165471_0	1287116.X734_31480	4.62e-162	524.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,2TTUK@28211|Alphaproteobacteria,43IWV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
LZS2_k127_3165471_1	926550.CLDAP_34850	2.487e-95	320.0	COG0647@1|root,COG0647@2|Bacteria,2G60W@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG0647 sugar phosphatase of the HAD superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
LZS2_k127_3165471_3	926569.ANT_19770	1.282e-25	111.0	COG1073@1|root,COG1073@2|Bacteria,2G690@200795|Chloroflexi	200795|Chloroflexi	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
LZS2_k127_3165471_4	595460.RRSWK_06053	0.0002488	47.0	2CIPX@1|root,33NST@2|Bacteria,2J1CU@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
LZS2_k127_3167948_3	395493.BegalDRAFT_2290	7.458e-90	305.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T216@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
LZS2_k127_3167948_1	1499967.BAYZ01000026_gene1633	2.883e-131	435.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF3404,HATPase_c,HisKA,PAS_8,Response_reg
LZS2_k127_3167948_2	118168.MC7420_1011	8.774e-100	337.0	COG0642@1|root,COG2205@2|Bacteria,1G0YJ@1117|Cyanobacteria,1H7ER@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_3167948_0	765420.OSCT_1228	9.224e-132	437.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_3167948_4	765420.OSCT_1229	3.686e-35	136.0	COG0745@1|root,COG0745@2|Bacteria	765420.OSCT_1229|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3177223_2	383372.Rcas_0488	1.288e-136	441.0	COG0171@1|root,COG0171@2|Bacteria,2G7JV@200795|Chloroflexi,375WH@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
LZS2_k127_3177223_0	383372.Rcas_0489	3.853e-307	953.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi,376WK@32061|Chloroflexia	32061|Chloroflexia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS2_k127_3177223_1	357808.RoseRS_3648	1.735e-236	740.0	COG0318@1|root,COG0318@2|Bacteria,2G5XY@200795|Chloroflexi,37755@32061|Chloroflexia	32061|Chloroflexia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS2_k127_3177223_6	926569.ANT_20020	2.477e-24	106.0	COG0236@1|root,COG0236@2|Bacteria,2G7GE@200795|Chloroflexi	200795|Chloroflexi	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS2_k127_3177223_5	443144.GM21_3210	1.12e-43	178.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_3177223_4	909663.KI867150_gene2301	6.328e-87	298.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_3177223_3	880073.Calab_2181	4.594e-105	350.0	COG0535@1|root,COG0535@2|Bacteria,2NPKA@2323|unclassified Bacteria	2|Bacteria	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
LZS2_k127_318580_5	926550.CLDAP_27790	2.465e-58	207.0	COG0438@1|root,COG0438@2|Bacteria,2G6JX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
LZS2_k127_318580_4	926550.CLDAP_27800	1.584e-70	257.0	COG3307@1|root,COG3307@2|Bacteria,2G7A2@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS2_k127_318580_3	926550.CLDAP_27810	1.102e-110	365.0	COG1216@1|root,COG1216@2|Bacteria,2G8DR@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
LZS2_k127_318580_2	926569.ANT_20330	4.603e-111	370.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	pelE	-	3.4.11.10,3.4.11.6,4.2.2.2	ko:K01728,ko:K19701	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM_2,CBM_6,Pec_lyase,Prenyltrans
LZS2_k127_318580_0	926569.ANT_20340	4.278e-145	469.0	COG1215@1|root,COG1215@2|Bacteria,2G8HN@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
LZS2_k127_318580_1	926569.ANT_02400	3.911e-137	447.0	COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS2_k127_318580_6	1128421.JAGA01000002_gene746	5.916e-16	77.0	COG0438@1|root,COG0438@2|Bacteria,2NRC9@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	pslH	-	-	ko:K21001	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
LZS2_k127_3191433_3	1122612.AUBA01000002_gene1757	1.611e-09	61.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PR9I@1224|Proteobacteria,2U1SM@28211|Alphaproteobacteria,2K253@204457|Sphingomonadales	204457|Sphingomonadales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Pyr_redox_3
LZS2_k127_3191433_0	518766.Rmar_2012	3.085e-320	991.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1FIVE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
LZS2_k127_3191433_1	926550.CLDAP_07160	8.509e-79	270.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
LZS2_k127_3191433_2	518766.Rmar_2014	5.877e-69	244.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,1FJC4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Domain present in carbohydrate binding proteins and sugar hydrolses	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
LZS2_k127_3237716_2	1304875.JAFZ01000001_gene1388	1.459e-62	223.0	COG0018@1|root,COG0018@2|Bacteria,3TA5K@508458|Synergistetes	508458|Synergistetes	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
LZS2_k127_3237716_1	1304880.JAGB01000001_gene546	8.035e-134	440.0	COG0235@1|root,COG0235@2|Bacteria,1UYFZ@1239|Firmicutes,24B39@186801|Clostridia	186801|Clostridia	G	PFAM class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
LZS2_k127_3237716_0	696369.KI912183_gene1927	5.41e-137	473.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,260VD@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM ATP-dependent DNA helicase, RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
LZS2_k127_3276174_0	326427.Cagg_1002	4.775e-55	218.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3276174_1	680198.SCAB_5351	5.085e-21	96.0	COG1879@1|root,COG1879@2|Bacteria,2HEHI@201174|Actinobacteria	201174|Actinobacteria	G	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
LZS2_k127_3289462_3	1254432.SCE1572_01455	2.959e-05	54.0	COG3386@1|root,COG3386@2|Bacteria,1R0BF@1224|Proteobacteria,43CTQ@68525|delta/epsilon subdivisions,2X818@28221|Deltaproteobacteria,2Z21M@29|Myxococcales	28221|Deltaproteobacteria	G	Disaggregatase related repeat	-	-	-	-	-	-	-	-	-	-	-	-	Disaggr_repeat
LZS2_k127_3289462_0	1128421.JAGA01000002_gene78	1.27e-34	153.0	COG1928@1|root,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
LZS2_k127_3289462_2	357808.RoseRS_0410	1.21e-08	68.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
LZS2_k127_3289462_1	926550.CLDAP_01930	5.421e-14	77.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
LZS2_k127_3289532_4	1128421.JAGA01000004_gene2521	5.315e-99	334.0	COG0006@1|root,COG0006@2|Bacteria,2NP41@2323|unclassified Bacteria	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	pepP	GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271,ko:K08326	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
LZS2_k127_3289532_7	926550.CLDAP_31390	4.567e-34	147.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926550.CLDAP_31390|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3289532_0	926569.ANT_23460	5.317e-141	458.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS2_k127_3289532_1	1382306.JNIM01000001_gene41	4.696e-139	454.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
LZS2_k127_3289532_8	485913.Krac_8644	1.329e-11	75.0	COG1589@1|root,COG1589@2|Bacteria,2G7FV@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
LZS2_k127_3289532_2	479434.Sthe_1990	1.701e-128	420.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
LZS2_k127_3289532_5	926569.ANT_23420	5.307e-90	306.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
LZS2_k127_3289532_6	383372.Rcas_4353	9.052e-52	186.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
LZS2_k127_3289532_3	926550.CLDAP_38070	1.333e-116	388.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_3309777_0	96561.Dole_3180	2.57e-100	334.0	COG0475@1|root,COG0569@1|root,COG1762@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria,1R9PF@1224|Proteobacteria,42RF1@68525|delta/epsilon subdivisions,2WMJJ@28221|Deltaproteobacteria,2MJ88@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,PTS_EIIA_2,TrkA_C,TrkA_N
LZS2_k127_3309777_2	926569.ANT_22570	6.551e-57	212.0	COG0392@1|root,COG0392@2|Bacteria,2G6EN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
LZS2_k127_3309777_4	357808.RoseRS_1335	2.698e-19	89.0	COG4481@1|root,COG4481@2|Bacteria,2G7GI@200795|Chloroflexi,37629@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
LZS2_k127_3309777_1	1121403.AUCV01000055_gene2985	5.614e-95	327.0	COG0707@1|root,COG0707@2|Bacteria,1QU89@1224|Proteobacteria	1224|Proteobacteria	M	UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase	-	-	2.4.1.315,2.4.1.46	ko:K03429,ko:K03715	ko00561,ko01100,map00561,map01100	-	R02689,R02691,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
LZS2_k127_3309777_3	1227484.C471_15677	7.014e-22	101.0	COG1522@1|root,arCOG01580@2157|Archaea,2XWVQ@28890|Euryarchaeota,23VGP@183963|Halobacteria	183963|Halobacteria	K	COG1522 Transcriptional regulators	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
LZS2_k127_3334053_5	1120999.JONM01000003_gene2723	1.148e-44	168.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,2KQ5T@206351|Neisseriales	206351|Neisseriales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
LZS2_k127_3334053_1	926569.ANT_01870	5.703e-121	396.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS2_k127_3334053_3	926550.CLDAP_21770	8.029e-96	321.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
LZS2_k127_3334053_8	675635.Psed_4297	7.016e-14	81.0	COG1073@1|root,COG1073@2|Bacteria,2IBIZ@201174|Actinobacteria	201174|Actinobacteria	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
LZS2_k127_3334053_0	1521187.JPIM01000024_gene697	6.789e-154	516.0	COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi,376GY@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS2_k127_3334053_4	316274.Haur_0593	2.302e-65	239.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_3334053_9	35841.BT1A1_1393	3.437e-11	74.0	COG1525@1|root,COG1525@2|Bacteria,1VASF@1239|Firmicutes,4IPMX@91061|Bacilli	91061|Bacilli	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
LZS2_k127_3334053_6	350688.Clos_1079	3.532e-23	109.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,36EVK@31979|Clostridiaceae	186801|Clostridia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_3334053_2	349741.Amuc_1436	1.828e-117	387.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
LZS2_k127_3334053_7	357808.RoseRS_2988	5.956e-20	97.0	COG1670@1|root,COG1670@2|Bacteria,2G9BF@200795|Chloroflexi,375XR@32061|Chloroflexia	32061|Chloroflexia	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
LZS2_k127_3343058_0	765420.OSCT_0643	6.792e-128	432.0	COG4585@1|root,COG4585@2|Bacteria,2G7W5@200795|Chloroflexi,3767N@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3343058_1	316274.Haur_3202	2.673e-72	248.0	COG2360@1|root,COG2360@2|Bacteria,2G8HE@200795|Chloroflexi,375I4@32061|Chloroflexia	32061|Chloroflexia	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
LZS2_k127_3343058_4	1122604.JONR01000011_gene3599	9.169e-06	55.0	2DWEZ@1|root,33ZZS@2|Bacteria,1NYBC@1224|Proteobacteria,1SQSQ@1236|Gammaproteobacteria,1XAUU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3343058_3	1479235.KK366039_gene2342	1.973e-16	80.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1XKIR@135619|Oceanospirillales	135619|Oceanospirillales	J	Translation initiation factor	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
LZS2_k127_3346936_7	431943.CKL_0584	4.091e-19	94.0	COG2020@1|root,COG2020@2|Bacteria,1V495@1239|Firmicutes,24IHG@186801|Clostridia,36FBJ@31979|Clostridiaceae	186801|Clostridia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
LZS2_k127_3346936_0	518766.Rmar_0522	6.071e-232	744.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1FJQW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	haloacid dehalogenase-like hydrolase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
LZS2_k127_3346936_4	517418.Ctha_0938	4.219e-59	212.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1FDZT@1090|Chlorobi	1090|Chlorobi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
LZS2_k127_3346936_1	616991.JPOO01000003_gene652	7.719e-207	653.0	COG0370@1|root,COG0370@2|Bacteria,4NGRN@976|Bacteroidetes,1I03Y@117743|Flavobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
LZS2_k127_3346936_2	945713.IALB_0510	1.003e-111	367.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
LZS2_k127_3346936_3	945713.IALB_0509	7.521e-85	293.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
LZS2_k127_3346936_8	402777.KB235904_gene4166	5.854e-08	55.0	COG2931@1|root,COG2931@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
LZS2_k127_3346936_6	485913.Krac_12187	1.593e-26	117.0	COG0745@1|root,COG0745@2|Bacteria	485913.Krac_12187|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3346936_5	1121472.AQWN01000002_gene2257	1.041e-36	146.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,2617E@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
LZS2_k127_3357750_2	309807.SRU_0542	1.054e-77	267.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
LZS2_k127_3357750_0	926569.ANT_13390	5.217e-99	327.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
LZS2_k127_3357750_3	72019.SARC_08110T0	3.323e-41	156.0	COG0219@1|root,2QQ5S@2759|Eukaryota,3ADU7@33154|Opisthokonta	33154|Opisthokonta	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
LZS2_k127_3357750_1	1192034.CAP_2956	2.208e-97	331.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,438ES@68525|delta/epsilon subdivisions,2X3PR@28221|Deltaproteobacteria,2YWSV@29|Myxococcales	28221|Deltaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
LZS2_k127_3357750_5	504472.Slin_2777	1.815e-05	49.0	2C25Y@1|root,3399H@2|Bacteria,4NXDI@976|Bacteroidetes,47SDB@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3357750_4	383372.Rcas_2492	3.235e-11	68.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi,377J0@32061|Chloroflexia	32061|Chloroflexia	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
LZS2_k127_3358509_7	66373.JOFQ01000007_gene3435	0.0005997	43.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
LZS2_k127_3358509_0	1191523.MROS_0754	1.052e-236	752.0	COG1361@1|root,COG1472@1|root,COG1361@2|Bacteria,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	bglX2	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Beta_helix,CUB,Calx-beta,DUF11,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14,SdrD_B
LZS2_k127_3358509_2	521460.Athe_1725	3.394e-73	254.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,42ES7@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
LZS2_k127_3358509_3	926569.ANT_12900	3.087e-62	229.0	COG0683@1|root,COG0683@2|Bacteria,2G6Q1@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS2_k127_3358509_4	314345.SPV1_07366	1.903e-44	174.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria	1224|Proteobacteria	D	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
LZS2_k127_3358509_1	382464.ABSI01000011_gene2837	2.157e-76	263.0	COG1011@1|root,COG1011@2|Bacteria,46ZKY@74201|Verrucomicrobia,2IVNQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS2_k127_3358509_5	1379698.RBG1_1C00001G1687	1.54e-40	154.0	2DNQ8@1|root,32YJ3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3358509_6	321332.CYB_2124	1.39e-12	76.0	COG0834@1|root,COG0834@2|Bacteria,1GJVF@1117|Cyanobacteria,1H1U5@1129|Synechococcus	1117|Cyanobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
LZS2_k127_3366339_2	644966.Tmar_1596	4.262e-36	142.0	COG0843@1|root,COG0843@2|Bacteria,1TP2U@1239|Firmicutes,24YCV@186801|Clostridia	186801|Clostridia	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.10.3.12,1.9.3.1	ko:K02274,ko:K02827	ko00190,ko01100,map00190,map01100	M00155,M00416	R00081,R09492	RC00016,RC00819	ko00000,ko00001,ko00002,ko01000	3.D.4.1,3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
LZS2_k127_3366339_1	926569.ANT_04310	3.927e-57	205.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_3366339_0	926569.ANT_04300	3.733e-76	278.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K03406,ko:K07673,ko:K07675	ko02020,ko02030,map02020,map02030	M00471,M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,LapD_MoxY_N
LZS2_k127_3366339_4	926569.ANT_26580	2.034e-12	71.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
LZS2_k127_3366339_5	926550.CLDAP_14440	7.611e-06	51.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
LZS2_k127_3366339_3	867903.ThesuDRAFT_01405	1.713e-19	92.0	298S5@1|root,313VY@2|Bacteria,1U9KD@1239|Firmicutes,25702@186801|Clostridia	186801|Clostridia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
LZS2_k127_3366339_6	867903.ThesuDRAFT_01405	1.542e-05	50.0	298S5@1|root,313VY@2|Bacteria,1U9KD@1239|Firmicutes,25702@186801|Clostridia	186801|Clostridia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
LZS2_k127_337167_0	1337936.IJ00_18240	6.825e-55	203.0	2DBEV@1|root,2Z8UT@2|Bacteria,1G3XJ@1117|Cyanobacteria,1HJN5@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_337167_1	497964.CfE428DRAFT_1239	1.097e-36	152.0	2BZ6D@1|root,2ZC6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3380790_9	1131812.JQMS01000001_gene1575	6.897e-80	271.0	COG1117@1|root,COG1117@2|Bacteria,4NFAB@976|Bacteroidetes,1HZHC@117743|Flavobacteriia,2NYNE@237|Flavobacterium	976|Bacteroidetes	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
LZS2_k127_3380790_6	1499967.BAYZ01000028_gene1313	3.547e-108	357.0	COG0581@1|root,COG0581@2|Bacteria,2NPJS@2323|unclassified Bacteria	2|Bacteria	P	phosphate transport system permease protein	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS2_k127_3380790_7	1499967.BAYZ01000028_gene1314	4.783e-106	353.0	COG0573@1|root,COG0573@2|Bacteria,2NPS2@2323|unclassified Bacteria	2|Bacteria	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS2_k127_3380790_8	1499967.BAYZ01000028_gene1315	3.221e-104	347.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS2_k127_3380790_12	926550.CLDAP_30060	1.315e-12	79.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,Usp
LZS2_k127_3380790_11	926550.CLDAP_30050	5.516e-72	250.0	COG0745@1|root,COG0745@2|Bacteria	926550.CLDAP_30050|-	T	phosphorelay signal transduction system	-	-	-	ko:K07670	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
LZS2_k127_3380790_10	1128421.JAGA01000001_gene2453	1.31e-72	270.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2NS4W@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	vncS	-	2.7.13.3	ko:K07641,ko:K10819	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_3380790_1	237368.SCABRO_02661	9.625e-219	688.0	COG1032@1|root,COG1032@2|Bacteria,2IXHH@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
LZS2_k127_3380790_3	926550.CLDAP_19650	1.946e-198	624.0	COG4948@1|root,COG4948@2|Bacteria,2G69R@200795|Chloroflexi	200795|Chloroflexi	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS2_k127_3380790_4	1121904.ARBP01000009_gene4376	1.311e-146	473.0	COG0003@1|root,COG0003@2|Bacteria,4NNW8@976|Bacteroidetes,47TGE@768503|Cytophagia	976|Bacteroidetes	D	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
LZS2_k127_3380790_2	926550.CLDAP_09870	2.953e-200	640.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
LZS2_k127_3380790_5	926550.CLDAP_33180	3.318e-108	361.0	COG1609@1|root,COG1609@2|Bacteria,2G8QM@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_3380790_0	935837.JAEK01000003_gene4108	1.23e-241	763.0	COG3408@1|root,COG3408@2|Bacteria,1UQ28@1239|Firmicutes,4HT8H@91061|Bacilli	91061|Bacilli	G	Bacterial Ig-like domain (group 4)	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,F5_F8_type_C,FIVAR,SLH
LZS2_k127_3381059_0	324602.Caur_2872	3.487e-133	432.0	COG1085@1|root,COG1085@2|Bacteria,2G6K5@200795|Chloroflexi,376AM@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM galactose-1-phosphate uridylyltransferase	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
LZS2_k127_3381059_1	518766.Rmar_0985	4.03e-45	171.0	COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,1FJB8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS2_k127_3381059_2	926569.ANT_03640	2.919e-44	170.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS2_k127_3395341_1	926550.CLDAP_27170	3.785e-141	458.0	COG4690@1|root,COG4690@2|Bacteria,2G7Y7@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
LZS2_k127_3395341_2	316274.Haur_1242	1.122e-134	437.0	COG1609@1|root,COG1609@2|Bacteria,2G8NB@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
LZS2_k127_3395341_0	316274.Haur_1243	9.104e-147	479.0	COG1653@1|root,COG1653@2|Bacteria,2G6MX@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
LZS2_k127_3395341_3	316274.Haur_1244	3.406e-124	407.0	COG1175@1|root,COG1175@2|Bacteria,2G8BY@200795|Chloroflexi,3773P@32061|Chloroflexia	2|Bacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10118,ko:K10189,ko:K10233,ko:K15771	ko02010,map02010	M00196,M00199,M00201,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.28,3.A.1.1.32,3.A.1.1.4,3.A.1.1.8	-	-	BPD_transp_1
LZS2_k127_3395341_4	316274.Haur_1245	1.684e-92	312.0	COG0395@1|root,COG0395@2|Bacteria,2G7QZ@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
LZS2_k127_3395341_5	446462.Amir_2986	6.418e-07	51.0	COG1501@1|root,COG1501@2|Bacteria,2GP4V@201174|Actinobacteria,4DZUF@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
LZS2_k127_3400776_0	926550.CLDAP_28180	2.232e-114	396.0	COG0642@1|root,COG0784@1|root,COG2204@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_3400776_2	926550.CLDAP_28170	2.107e-53	203.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
LZS2_k127_3400776_1	665571.STHERM_c07070	3.534e-57	205.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	gtsA	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_3407631_9	1499967.BAYZ01000095_gene4151	4.609e-65	227.0	COG1453@1|root,COG1453@2|Bacteria,2NNZZ@2323|unclassified Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
LZS2_k127_3407631_3	452637.Oter_3478	3.313e-198	621.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	74201|Verrucomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
LZS2_k127_3407631_1	204669.Acid345_3108	1.81e-229	723.0	COG0028@1|root,COG0028@2|Bacteria,3Y3GJ@57723|Acidobacteria,2JI90@204432|Acidobacteriia	204432|Acidobacteriia	EH	Acetolactate synthase, large subunit	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS2_k127_3407631_11	926569.ANT_03270	1.008e-50	185.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi	200795|Chloroflexi	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
LZS2_k127_3407631_0	221288.JH992901_gene993	8.411e-249	775.0	COG0059@1|root,COG0059@2|Bacteria,1G0NQ@1117|Cyanobacteria,1JHFF@1189|Stigonemataceae	2|Bacteria	EH	Acetohydroxy acid isomeroreductase, catalytic domain	ilvC	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iIT341.HP0330,iLF82_1304.LF82_1103	IlvC,IlvN
LZS2_k127_3407631_2	65071.PYU1_T007100	8.509e-226	714.0	COG0119@1|root,KOG2367@2759|Eukaryota,1ME2M@121069|Pythiales	121069|Pythiales	E	2-isopropylmalate synthase. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,LeuA_dimer
LZS2_k127_3407631_7	370438.PTH_0220	4.974e-106	352.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
LZS2_k127_3407631_10	525897.Dbac_1891	2.794e-64	231.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,42QZK@68525|delta/epsilon subdivisions,2WMZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS2_k127_3407631_8	479434.Sthe_0699	1.15e-91	308.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,27XI9@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
LZS2_k127_3407631_12	1165094.RINTHH_8520	2.144e-13	81.0	COG0535@1|root,COG0535@2|Bacteria,1G2HH@1117|Cyanobacteria,1HKYF@1161|Nostocales	1117|Cyanobacteria	S	4Fe-4S single cluster domain	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS2_k127_3407631_4	765420.OSCT_2914	2.234e-133	442.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	pds	-	1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6	ko:K00231,ko:K00514,ko:K02293,ko:K09879,ko:K21677	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	M00097,M00121	R03222,R04178,R04786,R04787,R04798,R04800,R07510,R07511,R07541,R07560,R07857,R07858,R09652,R09653,R09654,R09656,R09658	RC00885,RC01214,RC01901,RC01958,RC01959,RC01965,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS2_k127_3407631_6	1122222.AXWR01000026_gene1657	1.929e-106	351.0	COG1521@1|root,COG1521@2|Bacteria,1WI0G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
LZS2_k127_3407631_5	1122223.KB890700_gene1977	1.596e-117	390.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
LZS2_k127_3407631_13	502558.EGYY_03070	1.509e-05	56.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,2I6S6@201174|Actinobacteria,4CYMB@84998|Coriobacteriia	2|Bacteria	M	Domain of unknown function DUF11	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11
LZS2_k127_3411878_5	255470.cbdbA1648	4.666e-21	94.0	2A40N@1|root,30SJ6@2|Bacteria,2G9WM@200795|Chloroflexi,34DKR@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3411878_7	1499683.CCFF01000017_gene1498	1.136e-06	59.0	COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,24HJM@186801|Clostridia,36K23@31979|Clostridiaceae	186801|Clostridia	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
LZS2_k127_3411878_1	1121346.KB899809_gene3633	8.431e-100	337.0	28JP2@1|root,2Z9F4@2|Bacteria,1TS7D@1239|Firmicutes,4HC8V@91061|Bacilli,271SJ@186822|Paenibacillaceae	91061|Bacilli	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
LZS2_k127_3411878_2	1499967.BAYZ01000111_gene2961	8.21e-61	216.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	yisX	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
LZS2_k127_3411878_6	667015.Bacsa_0047	6.259e-19	88.0	2C0TM@1|root,32UWC@2|Bacteria,4NSYE@976|Bacteroidetes,2FTDD@200643|Bacteroidia,4ARJS@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
LZS2_k127_3411878_0	247490.KSU1_C1426	3.142e-124	406.0	COG0042@1|root,COG0042@2|Bacteria,2IYI5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
LZS2_k127_3411878_4	179408.Osc7112_4169	1.869e-31	136.0	COG1357@1|root,COG1357@2|Bacteria,1G02C@1117|Cyanobacteria,1H8G5@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_3411878_8	1536772.R70723_09900	6.317e-05	55.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,26QKX@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS2_k127_3411878_3	316274.Haur_4806	2.737e-47	177.0	COG0558@1|root,COG0558@2|Bacteria,2G9UJ@200795|Chloroflexi,377IH@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS2_k127_3413106_1	391009.Tmel_0614	1.1e-13	85.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
LZS2_k127_3413106_0	573061.Clocel_1305	3.34e-44	183.0	COG1387@1|root,COG3250@1|root,COG5263@1|root,COG5492@1|root,COG1387@2|Bacteria,COG3250@2|Bacteria,COG5263@2|Bacteria,COG5492@2|Bacteria,1UIHY@1239|Firmicutes,25FMJ@186801|Clostridia,36V3J@31979|Clostridiaceae	186801|Clostridia	EN	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
LZS2_k127_343102_3	189425.PGRAT_26505	2.695e-21	93.0	COG1131@1|root,COG1131@2|Bacteria,1TPJE@1239|Firmicutes,4HB5U@91061|Bacilli,26SG2@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	drrA_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162,SRP54
LZS2_k127_343102_0	44251.PDUR_14260	6.121e-138	443.0	COG1357@1|root,COG1357@2|Bacteria,1TR7H@1239|Firmicutes,4IPNR@91061|Bacilli,26SQK@186822|Paenibacillaceae	91061|Bacilli	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
LZS2_k127_343102_1	521011.Mpal_0870	9.142e-63	216.0	COG1695@1|root,arCOG00001@2157|Archaea,2Y29I@28890|Euryarchaeota,2NBA7@224756|Methanomicrobia	224756|Methanomicrobia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
LZS2_k127_343102_2	1121403.AUCV01000031_gene2842	8.799e-23	107.0	COG2931@1|root,COG3210@1|root,COG3897@1|root,COG4625@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3897@2|Bacteria,COG4625@2|Bacteria,1MU7T@1224|Proteobacteria,4345K@68525|delta/epsilon subdivisions,2X15Q@28221|Deltaproteobacteria,2MMPA@213118|Desulfobacterales	28221|Deltaproteobacteria	MQU	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_343102_4	383372.Rcas_1047	9.302e-13	82.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
LZS2_k127_3454710_2	926550.CLDAP_16350	1.108e-23	110.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	yjbF	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS2_k127_3454710_0	1191523.MROS_1660	8.581e-193	607.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
LZS2_k127_3454710_1	926550.CLDAP_20060	1.023e-116	397.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
LZS2_k127_3455869_5	316274.Haur_0717	8.888e-22	108.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_3455869_0	572477.Alvin_1133	1.046e-262	817.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1WWJT@135613|Chromatiales	135613|Chromatiales	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
LZS2_k127_3455869_3	926550.CLDAP_15580	3.206e-88	304.0	COG1159@1|root,COG1159@2|Bacteria,2G69C@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
LZS2_k127_3455869_1	1249634.D781_1221	4.23e-146	472.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,1RQ0C@1236|Gammaproteobacteria,3ZZIA@613|Serratia	1236|Gammaproteobacteria	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	GO:0000287,GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0071704,GO:1901575	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAF1260.b0757,iAPECO1_1312.APECO1_1331,iBWG_1329.BWG_0609,iEC55989_1330.EC55989_0736,iECABU_c1320.ECABU_c07960,iECB_1328.ECB_00710,iECDH1ME8569_1439.ECDH1ME8569_0710,iECH74115_1262.ECH74115_0860,iECIAI1_1343.ECIAI1_0725,iECNA114_1301.ECNA114_0687,iECO103_1326.ECO103_0745,iECOK1_1307.ECOK1_0757,iECP_1309.ECP_0768,iECS88_1305.ECS88_0773,iECSE_1348.ECSE_0810,iECSF_1327.ECSF_0683,iECSP_1301.ECSP_0810,iECW_1372.ECW_m0812,iECs_1301.ECs0785,iEKO11_1354.EKO11_3129,iETEC_1333.ETEC_0761,iEcDH1_1363.EcDH1_2885,iEcE24377_1341.EcE24377A_0784,iEcolC_1368.EcolC_2905,iG2583_1286.G2583_0923,iJO1366.b0757,iJR904.b0757,iLF82_1304.LF82_0794,iNRG857_1313.NRG857_03350,iUMN146_1321.UM146_13870,iUMNK88_1353.UMNK88_796,iUTI89_1310.UTI89_C0754,iWFL_1372.ECW_m0812,iY75_1357.Y75_RS03945,ic_1306.c0833	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
LZS2_k127_3455869_6	1385512.N784_04410	1.826e-18	96.0	COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,4I3FS@91061|Bacilli,2YB4H@289201|Pontibacillus	91061|Bacilli	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS2_k127_3455869_7	1123503.KB908056_gene1458	0.0004809	47.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria,2KFDC@204458|Caulobacterales	204458|Caulobacterales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
LZS2_k127_3455869_2	309801.trd_A0395	3.516e-125	422.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi,27XHZ@189775|Thermomicrobia	189775|Thermomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
LZS2_k127_3455869_4	102129.Lepto7375DRAFT_3867	6.318e-22	100.0	COG3424@1|root,COG3424@2|Bacteria,1G098@1117|Cyanobacteria	1117|Cyanobacteria	Q	synthase	-	-	-	ko:K16167,ko:K16233	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N,FAE1_CUT1_RppA
LZS2_k127_3456619_3	765420.OSCT_2127	5.89e-90	320.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3456619_2	926550.CLDAP_12670	2.374e-112	379.0	COG3307@1|root,COG3307@2|Bacteria,2G6B1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS2_k127_3456619_4	765420.OSCT_2831	3.694e-77	282.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
LZS2_k127_3456619_6	794903.OPIT5_14435	1.139e-41	159.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
LZS2_k127_3456619_1	794903.OPIT5_14440	2.4e-201	641.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia,3K78R@414999|Opitutae	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS2_k127_3456619_0	794903.OPIT5_14445	3.72e-245	766.0	COG4799@1|root,COG4799@2|Bacteria,46TGX@74201|Verrucomicrobia,3K75Y@414999|Opitutae	2|Bacteria	I	Carboxyl transferase domain	pccB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS2_k127_3456619_7	765420.OSCT_1551	2.746e-15	83.0	COG3025@1|root,COG3025@2|Bacteria	2|Bacteria	S	triphosphatase activity	-	-	3.6.1.25,4.6.1.1	ko:K01768,ko:K18446	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHAD,CYTH
LZS2_k127_3456619_5	926550.CLDAP_39600	1.558e-45	176.0	COG0539@1|root,COG0539@2|Bacteria,2G90B@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S1
LZS2_k127_3478398_1	926569.ANT_21930	1.314e-36	141.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.81,3.2.1.97	ko:K01219,ko:K17624	-	-	-	-	ko00000,ko01000	-	GH101	-	Big_2,CBM_6,Cytochrome_C7,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,WxL
LZS2_k127_3478398_2	648757.Rvan_1511	7.869e-36	153.0	COG4251@1|root,COG4251@2|Bacteria,1QYBI@1224|Proteobacteria,2TXM2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3
LZS2_k127_3478398_0	485913.Krac_6669	1.145e-66	234.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_3480189_4	1105031.HMPREF1141_2329	6.277e-44	168.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,36DKE@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
LZS2_k127_3480189_5	234267.Acid_1028	3.042e-10	64.0	COG2331@1|root,COG2331@2|Bacteria,3Y92S@57723|Acidobacteria	57723|Acidobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
LZS2_k127_3480189_0	926550.CLDAP_20840	1.5e-323	997.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
LZS2_k127_3480189_8	207559.Dde_0254	0.0003688	44.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2M9IV@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS2_k127_3480189_1	383372.Rcas_2023	1.503e-107	350.0	COG0693@1|root,COG0693@2|Bacteria,2G8B6@200795|Chloroflexi,3770W@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
LZS2_k127_3480189_2	1121930.AQXG01000005_gene597	1.044e-88	297.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,1IUKS@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS2_k127_3480189_7	1131814.JAFO01000001_gene2147	9.915e-05	56.0	2C8K7@1|root,31ZEM@2|Bacteria,1MYR9@1224|Proteobacteria,2URHI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3480189_3	1380390.JIAT01000010_gene4208	1.908e-46	187.0	COG1807@1|root,COG1807@2|Bacteria,2HNIC@201174|Actinobacteria,4CPHR@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_3480189_6	867845.KI911784_gene2873	5.664e-05	56.0	COG1807@1|root,COG1807@2|Bacteria,2G7UD@200795|Chloroflexi,3768B@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_3489780_1	1382306.JNIM01000001_gene1873	5.998e-67	248.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
LZS2_k127_3489780_0	357808.RoseRS_1273	8.045e-76	274.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
LZS2_k127_3508924_3	1410668.JNKC01000001_gene1876	0.0005555	44.0	COG2201@1|root,COG2201@2|Bacteria,1V3IU@1239|Firmicutes,24HJF@186801|Clostridia,36IRR@31979|Clostridiaceae	186801|Clostridia	NT	Chemotaxis protein cheY	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
LZS2_k127_3508924_2	1333523.L593_08855	1.593e-38	155.0	arCOG12705@1|root,arCOG12705@2157|Archaea,2Y5BC@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3508924_1	102129.Lepto7375DRAFT_7716	6.557e-50	181.0	COG0596@1|root,COG0596@2|Bacteria,1GFTY@1117|Cyanobacteria	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_3508924_0	1341679.P253_03044	2.664e-71	245.0	COG2452@1|root,COG2452@2|Bacteria,1QV30@1224|Proteobacteria,1RZMJ@1236|Gammaproteobacteria,3NSV1@468|Moraxellaceae	1236|Gammaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Resolvase
LZS2_k127_3511176_1	485913.Krac_7287	4.34e-26	109.0	COG3004@1|root,COG3004@2|Bacteria,2G7ZG@200795|Chloroflexi	200795|Chloroflexi	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
LZS2_k127_3511176_2	1160137.KB907308_gene6991	5.329e-06	52.0	COG2084@1|root,COG2084@2|Bacteria,2GTGE@201174|Actinobacteria,4G4IQ@85025|Nocardiaceae	201174|Actinobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,F420_oxidored,NAD_binding_2
LZS2_k127_3511176_0	926550.CLDAP_20730	0.0	1066.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
LZS2_k127_3518079_1	518766.Rmar_0439	3.669e-31	138.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1FJBA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
LZS2_k127_3518079_0	1041930.Mtc_0609	1.373e-69	248.0	COG1216@1|root,arCOG01383@2157|Archaea,2XW51@28890|Euryarchaeota,2N9HF@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
LZS2_k127_3518079_2	1041930.Mtc_0198	2.462e-30	128.0	COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
LZS2_k127_3527548_3	926550.CLDAP_23150	1.345e-68	256.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_3527548_1	926550.CLDAP_20010	5.024e-100	334.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,2G8HS@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_AraC
LZS2_k127_3527548_0	926550.CLDAP_20000	0.0	1464.0	COG0457@1|root,COG0457@2|Bacteria,2G77P@200795|Chloroflexi	200795|Chloroflexi	G	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107
LZS2_k127_3527548_2	868864.Dester_0837	1.469e-76	276.0	COG0459@1|root,COG0459@2|Bacteria,2G3V0@200783|Aquificae	200783|Aquificae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS2_k127_3527548_5	1541065.JRFE01000012_gene2450	3.603e-33	140.0	COG4447@1|root,COG4447@2|Bacteria,1G2KP@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
LZS2_k127_3527548_4	671143.DAMO_0981	4.332e-43	159.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS2_k127_3533953_1	479434.Sthe_1016	1.198e-28	118.0	COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi,27Y9U@189775|Thermomicrobia	189775|Thermomicrobia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS2_k127_3533953_2	926550.CLDAP_22170	1.447e-22	99.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi	200795|Chloroflexi	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS2_k127_3533953_0	926569.ANT_20510	9.516e-131	425.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
LZS2_k127_3535973_1	867903.ThesuDRAFT_02083	3.624e-167	540.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WCXQ@538999|Clostridiales incertae sedis	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS2_k127_3535973_4	926569.ANT_11400	4.23e-123	426.0	COG0768@1|root,COG0772@1|root,COG0768@2|Bacteria,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
LZS2_k127_3535973_6	926550.CLDAP_37700	1.377e-104	347.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
LZS2_k127_3535973_7	2325.TKV_c04220	2.242e-84	292.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,24BAN@186801|Clostridia,42F2W@68295|Thermoanaerobacterales	186801|Clostridia	C	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
LZS2_k127_3535973_8	1414720.CBYM010000003_gene406	3.51e-14	79.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,36ICD@31979|Clostridiaceae	186801|Clostridia	V	PFAM VanZ	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
LZS2_k127_3535973_3	926569.ANT_04660	7.312e-138	444.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
LZS2_k127_3535973_2	880073.Calab_0989	2.39e-155	496.0	COG0667@1|root,COG0667@2|Bacteria,2NP23@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
LZS2_k127_3535973_0	926550.CLDAP_19690	3.352e-293	914.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi	200795|Chloroflexi	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
LZS2_k127_3535973_10	525904.Tter_0104	0.0003134	46.0	COG1215@1|root,COG1215@2|Bacteria,2NPW4@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_3535973_5	635013.TherJR_2837	1.172e-113	373.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_3538181_1	1128421.JAGA01000002_gene165	2.595e-74	254.0	COG2896@1|root,COG2896@2|Bacteria,2NP5R@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
LZS2_k127_3538181_4	926569.ANT_17990	1.064e-37	149.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
LZS2_k127_3538181_0	886293.Sinac_5547	5.066e-254	811.0	COG0377@1|root,COG0649@1|root,COG0852@1|root,COG0377@2|Bacteria,COG0649@2|Bacteria,COG0852@2|Bacteria,2IYN8@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
LZS2_k127_3538181_2	926569.ANT_18220	1.001e-60	226.0	COG1143@1|root,COG1143@2|Bacteria,2G6SE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K00338,ko:K03615	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
LZS2_k127_3538181_3	1056512.D515_01302	1.198e-43	175.0	COG3743@1|root,COG3743@2|Bacteria,1RA3K@1224|Proteobacteria,1S9SF@1236|Gammaproteobacteria,1XXMJ@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
LZS2_k127_3539845_3	479434.Sthe_0479	3.989e-06	49.0	COG0438@1|root,COG0438@2|Bacteria,2G67A@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_3539845_0	479434.Sthe_0803	1.541e-54	204.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi,27XQX@189775|Thermomicrobia	189775|Thermomicrobia	C	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
LZS2_k127_3539845_2	926550.CLDAP_06120	1.048e-20	99.0	COG1418@1|root,COG1418@2|Bacteria,2G7CI@200795|Chloroflexi	200795|Chloroflexi	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3539845_1	717606.PaecuDRAFT_0258	3.958e-35	144.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4HHK2@91061|Bacilli,26TT2@186822|Paenibacillaceae	91061|Bacilli	S	zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
LZS2_k127_3546405_4	1173021.ALWA01000010_gene1468	3.916e-37	147.0	COG1309@1|root,COG1309@2|Bacteria,1G61G@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
LZS2_k127_3546405_3	196162.Noca_1656	1.876e-63	224.0	COG0001@1|root,COG0235@1|root,COG0001@2|Bacteria,COG0235@2|Bacteria,2IBG2@201174|Actinobacteria,4DQG9@85009|Propionibacteriales	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_3546405_0	1523503.JPMY01000028_gene266	1.342e-227	713.0	COG0001@1|root,COG0001@2|Bacteria,1NRZ1@1224|Proteobacteria	1224|Proteobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_3546405_1	1220582.RRU01S_01_00210	1.707e-193	616.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2TR7P@28211|Alphaproteobacteria,4BCCU@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	FGGY family of carbohydrate kinases, C-terminal domain	xylBch	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
LZS2_k127_3546405_2	1304865.JAGF01000001_gene1436	6.388e-177	562.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_3546405_11	1550091.JROE01000023_gene3910	0.0006069	52.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4PNF8@976|Bacteroidetes,1IVRD@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DUF11,Invasin_D3
LZS2_k127_3546405_5	324602.Caur_3114	9.664e-33	134.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
LZS2_k127_3546405_7	326427.Cagg_3758	2.334e-16	92.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3546405_9	661478.OP10G_0131	6.446e-05	47.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS2_k127_3546405_8	309801.trd_1014	1.929e-05	46.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,2G6KJ@200795|Chloroflexi,27YNQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156,LPG_synthase_TM
LZS2_k127_354906_9	553973.CLOHYLEM_04358	3.301e-14	73.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
LZS2_k127_354906_7	411467.BACCAP_00087	2.571e-28	117.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,26997@186813|unclassified Clostridiales	186801|Clostridia	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
LZS2_k127_354906_6	1441930.Z042_06805	2.559e-48	187.0	COG0269@1|root,COG0269@2|Bacteria,1QWE4@1224|Proteobacteria,1RRCI@1236|Gammaproteobacteria,4005P@613|Serratia	1236|Gammaproteobacteria	G	Catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate	sgbH	GO:0003674,GO:0003824,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016831,GO:0033982,GO:0044238,GO:0071704,GO:1901575	4.1.1.85,4.1.2.43	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	M00345,M00550,M00580	R05338,R07125	RC00421,RC00422,RC01721	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2128,iNRG857_1313.NRG857_17835	OMPdecase
LZS2_k127_354906_2	670487.Ocepr_1040	8.966e-106	352.0	COG2390@1|root,COG2390@2|Bacteria,1WMUX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sugar-bind
LZS2_k127_354906_1	926550.CLDAP_12660	9.006e-126	409.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
LZS2_k127_354906_11	1122602.ATXP01000021_gene139	0.0002152	45.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS2_k127_354906_10	935567.JAES01000008_gene1990	5.26e-11	78.0	COG1652@1|root,COG1652@2|Bacteria,1N3P8@1224|Proteobacteria,1SY85@1236|Gammaproteobacteria,1X82C@135614|Xanthomonadales	135614|Xanthomonadales	S	peptidoglycan-binding protein, lysm	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_354906_5	316274.Haur_0080	3.393e-59	237.0	COG0726@1|root,COG0726@2|Bacteria,2G8CG@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS2_k127_354906_4	1232410.KI421416_gene2631	2.338e-67	263.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,42NSR@68525|delta/epsilon subdivisions,2WR56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
LZS2_k127_354906_8	858215.Thexy_0378	2.651e-15	92.0	COG1388@1|root,COG1388@2|Bacteria,1UHZC@1239|Firmicutes,25E80@186801|Clostridia,42FCR@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
LZS2_k127_354906_3	1173028.ANKO01000102_gene5411	2.057e-102	338.0	COG1656@1|root,COG1656@2|Bacteria,1G344@1117|Cyanobacteria,1HAHV@1150|Oscillatoriales	1117|Cyanobacteria	S	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
LZS2_k127_354906_0	357808.RoseRS_4542	2.002e-166	532.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi,3752D@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS2_k127_3588758_0	56110.Oscil6304_0877	1.873e-190	604.0	COG2723@1|root,COG2723@2|Bacteria,1G3QH@1117|Cyanobacteria,1HH9N@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
LZS2_k127_3588758_1	555088.DealDRAFT_0639	2.238e-171	546.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,42KCG@68298|Syntrophomonadaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73	ko:K00052,ko:K07246	ko00290,ko00630,ko00650,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00630,map00650,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00215,R00994,R01751,R02545,R04426,R06180,R10052	RC00084,RC00105,RC00417,RC00594,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS2_k127_3588758_3	926550.CLDAP_22240	2.686e-130	432.0	COG1215@1|root,COG1215@2|Bacteria,2G952@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,T2SSE_N
LZS2_k127_3588758_5	1521187.JPIM01000125_gene3595	5.09e-71	273.0	COG3307@1|root,COG3664@1|root,COG3307@2|Bacteria,COG3664@2|Bacteria,2G6AB@200795|Chloroflexi,375CF@32061|Chloroflexia	32061|Chloroflexia	GM	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Wzy_C
LZS2_k127_3588758_9	1396.DJ87_1997	4.807e-10	68.0	COG1514@1|root,COG1514@2|Bacteria,1VBG1@1239|Firmicutes,4IMER@91061|Bacilli,1ZJZC@1386|Bacillus	91061|Bacilli	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
LZS2_k127_3588758_8	926550.CLDAP_26050	4.677e-18	87.0	COG1357@1|root,COG1357@2|Bacteria,2G7HW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_3588758_7	765420.OSCT_1641	7.155e-38	156.0	COG1073@1|root,COG1073@2|Bacteria,2GAEG@200795|Chloroflexi,375SF@32061|Chloroflexia	32061|Chloroflexia	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_3588758_4	102129.Lepto7375DRAFT_8055	7.079e-76	261.0	28XBK@1|root,2ZJ9G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3588758_6	195250.CM001776_gene1729	2.235e-58	208.0	2DUA0@1|root,33PJB@2|Bacteria,1GD0Q@1117|Cyanobacteria,1H0Y9@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3588758_2	195250.CM001776_gene1730	1.682e-134	433.0	COG0155@1|root,COG0155@2|Bacteria,1GBHK@1117|Cyanobacteria,1GZPM@1129|Synechococcus	1117|Cyanobacteria	P	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
LZS2_k127_3600058_2	383372.Rcas_4113	7.625e-71	245.0	COG0247@1|root,COG0247@2|Bacteria,2G7VD@200795|Chloroflexi,3754W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
LZS2_k127_3600058_1	867845.KI911784_gene102	4.711e-79	279.0	COG3075@1|root,COG3075@2|Bacteria,2G877@200795|Chloroflexi,374VB@32061|Chloroflexia	32061|Chloroflexia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
LZS2_k127_3600058_0	867845.KI911784_gene101	1.509e-93	316.0	COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi,3750F@32061|Chloroflexia	32061|Chloroflexia	C	BFD domain protein 2Fe-2S -binding domain protein	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
LZS2_k127_3602408_7	134676.ACPL_1281	5.661e-08	60.0	COG2197@1|root,COG2197@2|Bacteria,2GJ5I@201174|Actinobacteria	201174|Actinobacteria	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_3602408_1	63737.Npun_F5035	3.033e-146	500.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3290@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,1G09B@1117|Cyanobacteria,1HRFM@1161|Nostocales	1117|Cyanobacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_3602408_5	177437.HRM2_25760	3.56e-68	241.0	COG2199@1|root,COG3706@2|Bacteria,1QWNG@1224|Proteobacteria,42SDQ@68525|delta/epsilon subdivisions,2WP1N@28221|Deltaproteobacteria,2MK84@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
LZS2_k127_3602408_4	1123326.JFBL01000003_gene1903	2.003e-68	244.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,42MU0@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
LZS2_k127_3602408_6	1123326.JFBL01000003_gene1903	5.418e-43	171.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,42MU0@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
LZS2_k127_3602408_0	1499967.BAYZ01000105_gene3479	1.634e-278	916.0	COG0745@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,2NS5N@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
LZS2_k127_3602408_2	111780.Sta7437_4190	6.044e-109	366.0	COG0642@1|root,COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2208@2|Bacteria,1G160@1117|Cyanobacteria,3VJ6C@52604|Pleurocapsales	1117|Cyanobacteria	KT	Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE,HATPase_c,HisKA,Response_reg,SpoIIE
LZS2_k127_3602408_3	656519.Halsa_0193	9.885e-82	292.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,3WBA3@53433|Halanaerobiales	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
LZS2_k127_3604465_0	383372.Rcas_2448	6.869e-179	567.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	ogl	-	4.2.2.6	ko:K01730,ko:K03641	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	PD40,Pectate_lyase22
LZS2_k127_3604465_1	1002809.SSIL_2372	2.673e-27	115.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,4HDV0@91061|Bacilli	91061|Bacilli	M	Belongs to the glycosyl hydrolase 28 family	picA	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
LZS2_k127_3618518_0	1499967.BAYZ01000095_gene4151	1.266e-133	432.0	COG1453@1|root,COG1453@2|Bacteria,2NNZZ@2323|unclassified Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
LZS2_k127_3618518_1	485913.Krac_7279	2.049e-101	337.0	COG3386@1|root,COG3386@2|Bacteria,2G76H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM SMP-30 Gluconolaconase LRE domain protein	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
LZS2_k127_3618518_2	1168034.FH5T_04425	6.158e-35	143.0	COG3884@1|root,COG3884@2|Bacteria,4NMMY@976|Bacteroidetes,2FQ43@200643|Bacteroidia	976|Bacteroidetes	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
LZS2_k127_3618518_3	1047013.AQSP01000091_gene649	1.084e-29	132.0	COG2227@1|root,COG3408@1|root,COG2227@2|Bacteria,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,CBM_6,Crystall,Glyco_hydro_64,Methyltransf_11,Methyltransf_23,RicinB_lectin_2,SLH
LZS2_k127_3619103_11	1500304.JQKY01000015_gene1919	2.469e-11	78.0	COG0642@1|root,COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,2U1UX@28211|Alphaproteobacteria,4B83E@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
LZS2_k127_3619103_0	1499967.BAYZ01000108_gene2206	2.496e-133	463.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
LZS2_k127_3619103_9	926569.ANT_11810	1.461e-26	127.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
LZS2_k127_3619103_4	1123355.JHYO01000013_gene1130	5.6e-50	203.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,36Y67@31993|Methylocystaceae	28211|Alphaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
LZS2_k127_3619103_8	926569.ANT_11830	6.311e-31	143.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
LZS2_k127_3619103_1	1499967.BAYZ01000108_gene2206	4.459e-97	355.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
LZS2_k127_3619103_6	316274.Haur_1217	4.389e-40	171.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_3619103_12	1038866.KB902773_gene863	0.0005347	53.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3JS5D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_7,dCache_1
LZS2_k127_3619103_3	118161.KB235922_gene842	1.028e-82	301.0	COG0840@1|root,COG2770@1|root,COG0840@2|Bacteria,COG2770@2|Bacteria,1G07J@1117|Cyanobacteria,3VKYQ@52604|Pleurocapsales	1117|Cyanobacteria	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	GAF,HAMP,MCPsignal,MHYT,PAS_9,dCache_1
LZS2_k127_3619103_2	335543.Sfum_2629	2.548e-84	308.0	COG2202@1|root,COG2770@1|root,COG3920@1|root,COG2202@2|Bacteria,COG2770@2|Bacteria,COG3920@2|Bacteria,1NWNJ@1224|Proteobacteria,43BNW@68525|delta/epsilon subdivisions,2X7QA@28221|Deltaproteobacteria,2MRJS@213462|Syntrophobacterales	68525|delta/epsilon subdivisions	T	PFAM ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_2,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_3619103_5	926569.ANT_11800	7.699e-44	182.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
LZS2_k127_3619103_10	573413.Spirs_1702	4.275e-25	115.0	COG0226@1|root,COG0226@2|Bacteria,2J7NC@203691|Spirochaetes	203691|Spirochaetes	P	Phosphate ABC transporter, periplasmic phosphate-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS2_k127_3619103_7	316274.Haur_1217	1.17e-32	143.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_362210_0	926569.ANT_22300	3.024e-14	85.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,fn3
LZS2_k127_3625003_2	368407.Memar_2230	4.418e-18	86.0	COG1208@1|root,arCOG00668@2157|Archaea,2Y87G@28890|Euryarchaeota,2N9FU@224756|Methanomicrobia	224756|Methanomicrobia	M	transferase hexapeptide repeat containing protein	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS2_k127_3625003_0	1121929.KB898662_gene603	9.6e-110	368.0	COG0153@1|root,COG0153@2|Bacteria,1VUAT@1239|Firmicutes,4HXHM@91061|Bacilli	91061|Bacilli	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3625003_1	926550.CLDAP_32480	3.534e-51	203.0	COG1807@1|root,COG1807@2|Bacteria	926550.CLDAP_32480|-	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3626416_10	926569.ANT_18400	1.824e-37	151.0	COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3626416_12	332101.JIBU02000023_gene4853	2.557e-16	84.0	COG2076@1|root,COG2076@2|Bacteria,1VF8J@1239|Firmicutes,24JJ4@186801|Clostridia,36JY9@31979|Clostridiaceae	186801|Clostridia	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_3626416_9	479434.Sthe_1787	2.67e-54	216.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_3626416_13	1123035.ARLA01000027_gene535	4.623e-12	77.0	COG0500@1|root,COG2226@2|Bacteria,4PGF8@976|Bacteroidetes,1IA5F@117743|Flavobacteriia	976|Bacteroidetes	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_3626416_6	316274.Haur_0091	3.807e-82	282.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
LZS2_k127_3626416_1	926569.ANT_15600	9.234e-253	797.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
LZS2_k127_3626416_11	660470.Theba_1378	1.838e-17	85.0	COG1146@1|root,COG1146@2|Bacteria,2GDEK@200918|Thermotogae	200918|Thermotogae	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
LZS2_k127_3626416_2	926550.CLDAP_25810	1.038e-144	467.0	COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
LZS2_k127_3626416_4	1304880.JAGB01000002_gene1752	1.956e-107	353.0	COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia	186801|Clostridia	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
LZS2_k127_3626416_7	926569.ANT_04520	6.208e-56	201.0	COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.1,1.2.7.3	ko:K00172,ko:K00177	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00307,M00374,M00620	R01196,R01197,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
LZS2_k127_3626416_3	1120971.AUCA01000019_gene1136	1.319e-128	420.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27949@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_3626416_8	290317.Cpha266_2365	7.425e-56	203.0	COG1028@1|root,COG1028@2|Bacteria	290317.Cpha266_2365|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3626416_0	706587.Desti_4459	1.704e-254	814.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2MRG0@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
LZS2_k127_3626416_14	338966.Ppro_1841	2.556e-06	55.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
LZS2_k127_3626416_5	1121430.JMLG01000030_gene1600	2.656e-105	349.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,26492@186807|Peptococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
LZS2_k127_3630223_1	1230457.C476_10906	3.149e-46	174.0	COG3358@1|root,arCOG04570@2157|Archaea,2XX3J@28890|Euryarchaeota,23VM5@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
LZS2_k127_3630223_0	926569.ANT_03860	9.869e-68	240.0	COG0621@1|root,COG0621@2|Bacteria,2G5ZJ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
LZS2_k127_3631951_6	32057.KB217472_gene7871	2.351e-15	88.0	COG0683@1|root,COG1672@1|root,COG0683@2|Bacteria,COG1672@2|Bacteria,1G4E9@1117|Cyanobacteria	1117|Cyanobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	AAA_16,Peripla_BP_6,TPR_16
LZS2_k127_3631951_4	357808.RoseRS_2782	3.003e-24	111.0	COG0500@1|root,COG2226@2|Bacteria,2G724@200795|Chloroflexi,377H0@32061|Chloroflexia	32061|Chloroflexia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_3631951_0	309799.DICTH_0538	2.055e-112	377.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	bioF	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_3631951_2	383372.Rcas_0037	5.079e-84	286.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi,375AQ@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA repair protein RadC	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
LZS2_k127_3631951_3	525904.Tter_0199	1.513e-26	111.0	COG1917@1|root,COG1917@2|Bacteria,2NRCD@2323|unclassified Bacteria	2|Bacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS2_k127_3631951_7	96561.Dole_1550	4.009e-15	80.0	COG1028@1|root,COG1545@1|root,COG3255@1|root,COG3425@1|root,COG1028@2|Bacteria,COG1545@2|Bacteria,COG3255@2|Bacteria,COG3425@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria,2MHRA@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,MaoC_dehydrat_N,MaoC_dehydratas,OB_aCoA_assoc,SCP2,adh_short
LZS2_k127_3631951_5	640512.BC1003_1916	5.519e-20	91.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,2VVVU@28216|Betaproteobacteria,1K9RD@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
LZS2_k127_3631951_1	926550.CLDAP_34270	5.229e-97	323.0	COG1482@1|root,COG1482@2|Bacteria,2G6I2@200795|Chloroflexi	200795|Chloroflexi	G	PFAM mannose-6-phosphate isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
LZS2_k127_3660433_2	926569.ANT_07600	1.026e-111	366.0	COG0483@1|root,COG0483@2|Bacteria,2G7NN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
LZS2_k127_3660433_0	1489678.RDMS_00305	1.083e-204	644.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,1WM5K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the 3-oxoacid CoA-transferase family	-	-	2.8.3.5	ko:K01027	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS2_k127_3660433_3	926569.ANT_30330	3.974e-85	310.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
LZS2_k127_3660433_4	1382356.JQMP01000004_gene72	7.521e-72	252.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi,27XJ7@189775|Thermomicrobia	189775|Thermomicrobia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
LZS2_k127_3660433_5	326427.Cagg_2336	4.524e-28	128.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi,375MS@32061|Chloroflexia	32061|Chloroflexia	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
LZS2_k127_3660433_1	525904.Tter_1758	2.648e-159	515.0	COG1160@1|root,COG1160@2|Bacteria,2NNTW@2323|unclassified Bacteria	2|Bacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.399,1.1.1.95	ko:K00058,ko:K03977	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko03009,ko04147	-	-	-	KH_dom-like,MMR_HSR1
LZS2_k127_3660433_6	1307761.L21SP2_1583	1.899e-13	76.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
LZS2_k127_3661057_0	1128421.JAGA01000002_gene482	1.943e-198	633.0	COG0445@1|root,COG0445@2|Bacteria,2NNXQ@2323|unclassified Bacteria	2|Bacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
LZS2_k127_3661057_2	926569.ANT_14000	6.751e-42	163.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
LZS2_k127_3661057_1	56780.SYN_02058	5.147e-107	364.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MSKF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
LZS2_k127_3661941_3	525904.Tter_0164	2.04e-34	133.0	COG1940@1|root,COG1940@2|Bacteria,2NQJS@2323|unclassified Bacteria	2|Bacteria	GK	ROK family	scrK	-	2.7.1.2,2.7.1.4	ko:K00845,ko:K00847	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS2_k127_3661941_0	1173264.KI913949_gene731	9.23e-87	293.0	COG1296@1|root,COG1296@2|Bacteria,1GA6Q@1117|Cyanobacteria	1117|Cyanobacteria	E	branched-chain amino acid permease (azaleucine resistance)	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
LZS2_k127_3661941_4	1121405.dsmv_1524	1.818e-23	103.0	COG4392@1|root,COG4392@2|Bacteria,1NAPF@1224|Proteobacteria,432FK@68525|delta/epsilon subdivisions,2WXDN@28221|Deltaproteobacteria,2MME1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
LZS2_k127_3661941_1	926569.ANT_29790	8.931e-57	205.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
LZS2_k127_3661941_2	1123278.KB893399_gene4144	1.202e-42	169.0	COG2374@1|root,COG3420@1|root,COG4886@1|root,COG2374@2|Bacteria,COG3420@2|Bacteria,COG4886@2|Bacteria,4PPFY@976|Bacteroidetes,47KXR@768503|Cytophagia	976|Bacteroidetes	G	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,He_PIG
LZS2_k127_3667474_0	926550.CLDAP_11930	9.29e-48	197.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,PTPS_related
LZS2_k127_3676267_4	391625.PPSIR1_34013	5.79e-19	102.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1R45Z@1224|Proteobacteria,43AMH@68525|delta/epsilon subdivisions,2X61H@28221|Deltaproteobacteria,2Z38T@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,Guanylate_cyc
LZS2_k127_3676267_3	357808.RoseRS_1618	4.092e-32	145.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
LZS2_k127_3676267_1	1278309.KB907103_gene1174	9.541e-90	301.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,1RRRU@1236|Gammaproteobacteria,1XHS1@135619|Oceanospirillales	135619|Oceanospirillales	E	phosphoserine phosphatase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
LZS2_k127_3676267_0	926569.ANT_11950	3.941e-230	728.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
LZS2_k127_3676267_5	706587.Desti_3963	5.031e-09	60.0	COG0348@1|root,COG0348@2|Bacteria,1R4WT@1224|Proteobacteria	1224|Proteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
LZS2_k127_3676267_2	1449126.JQKL01000029_gene2562	6.257e-39	153.0	COG1280@1|root,COG1280@2|Bacteria,1V725@1239|Firmicutes,24KQ7@186801|Clostridia	186801|Clostridia	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
LZS2_k127_3676267_7	479434.Sthe_0370	1.995e-07	62.0	2DW90@1|root,33Z49@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3676267_6	485913.Krac_5906	1.122e-08	66.0	COG4283@1|root,COG4283@2|Bacteria,2G9AR@200795|Chloroflexi	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
LZS2_k127_3676267_8	292459.STH2646	4.585e-05	53.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
LZS2_k127_3696484_2	1347369.CCAD010000074_gene3476	3.683e-28	131.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,1ZE89@1386|Bacillus	91061|Bacilli	KT	COG2909 ATP-dependent transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,BTAD,TPR_12,TPR_8
LZS2_k127_3696484_4	644968.DFW101_0868	1.385e-05	58.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2WKC5@28221|Deltaproteobacteria,2M8BD@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5,Response_reg
LZS2_k127_3696484_1	1502851.FG93_00182	1.729e-38	167.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
LZS2_k127_3696484_0	1121396.KB893071_gene1279	5.001e-72	254.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2MIKY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS2_k127_3696484_3	314230.DSM3645_13460	5.249e-17	82.0	COG1694@1|root,COG1694@2|Bacteria,2J0FY@203682|Planctomycetes	203682|Planctomycetes	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
LZS2_k127_3706155_3	645991.Sgly_1838	1.762e-62	225.0	COG0715@1|root,COG0715@2|Bacteria,1UY07@1239|Firmicutes,24EN3@186801|Clostridia,260KN@186807|Peptococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system, periplasmic component	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
LZS2_k127_3706155_0	926560.KE387027_gene789	4.808e-114	389.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_3706155_2	926550.CLDAP_13410	2.023e-95	321.0	COG0412@1|root,COG0412@2|Bacteria,2G6NY@200795|Chloroflexi	200795|Chloroflexi	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
LZS2_k127_3706155_1	469383.Cwoe_1065	2.936e-109	362.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4CS06@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_370855_4	926550.CLDAP_30950	4.025e-60	215.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
LZS2_k127_370855_0	926569.ANT_05900	7.961e-177	562.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_370855_2	316274.Haur_0220	1.272e-130	425.0	COG0180@1|root,COG0180@2|Bacteria,2G5SH@200795|Chloroflexi,37647@32061|Chloroflexia	32061|Chloroflexia	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS2_k127_370855_3	926550.CLDAP_27220	1.287e-90	304.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi	200795|Chloroflexi	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
LZS2_k127_370855_1	1121447.JONL01000010_gene2381	5.078e-146	478.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42R3Z@68525|delta/epsilon subdivisions,2WN4D@28221|Deltaproteobacteria,2MGMW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
LZS2_k127_3710350_2	926569.ANT_19480	1.658e-27	116.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
LZS2_k127_3710350_3	1382306.JNIM01000001_gene133	1.738e-22	104.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
LZS2_k127_3710350_1	926550.CLDAP_40040	5.38e-40	154.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
LZS2_k127_3710350_4	1303518.CCALI_01646	7.817e-09	64.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	ComFC	-	-	-	-	-	-	-	-	-	-	-	DZR,Pribosyltran,zinc_ribbon_2
LZS2_k127_3710350_0	926550.CLDAP_38270	1.422e-43	173.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
LZS2_k127_3719935_2	1408303.JNJJ01000103_gene2428	6.521e-66	238.0	28JEU@1|root,2Z98W@2|Bacteria,1VRU4@1239|Firmicutes,4HTWS@91061|Bacilli	91061|Bacilli	S	PFAM MULE transposase, conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3719935_3	1536772.R70723_30360	1.168e-14	82.0	2DHHI@1|root,2ZZSX@2|Bacteria,1TYZA@1239|Firmicutes,4I85M@91061|Bacilli,26YYV@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
LZS2_k127_3719935_0	357808.RoseRS_0320	8.103e-269	832.0	COG3033@1|root,COG3033@2|Bacteria,2G7YV@200795|Chloroflexi,376SB@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS2_k127_3719935_1	357808.RoseRS_4317	4.765e-139	455.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi,375D0@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
LZS2_k127_3731457_0	1192034.CAP_3564	1.239e-218	685.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_3731457_2	926550.CLDAP_05980	6.413e-100	337.0	COG3842@1|root,COG3842@2|Bacteria,2G6S3@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE_2
LZS2_k127_3731457_1	926569.ANT_13340	3.03e-168	560.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
LZS2_k127_3747963_0	573413.Spirs_4115	1.817e-208	661.0	COG1640@1|root,COG1640@2|Bacteria,2J5U4@203691|Spirochaetes	203691|Spirochaetes	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
LZS2_k127_3748133_8	143224.JQMD01000002_gene75	1.867e-133	428.0	COG1482@1|root,COG1482@2|Bacteria,4NGGP@976|Bacteroidetes	976|Bacteroidetes	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3748133_1	595460.RRSWK_01727	6.674e-185	584.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_3748133_3	1121011.AUCB01000002_gene481	7.593e-169	536.0	COG1082@1|root,COG1082@2|Bacteria,4NFSP@976|Bacteroidetes,1HZ9M@117743|Flavobacteriia,23G94@178469|Arenibacter	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS2_k127_3748133_13	658088.HMPREF0987_02118	1.889e-28	123.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,27KMX@186928|unclassified Lachnospiraceae	186801|Clostridia	K	FCD	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
LZS2_k127_3748133_0	1128421.JAGA01000001_gene2213	8.244e-192	609.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
LZS2_k127_3748133_9	1128421.JAGA01000001_gene2214	1.959e-125	409.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
LZS2_k127_3748133_10	1128421.JAGA01000001_gene2215	2.841e-114	377.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_3748133_6	1128421.JAGA01000001_gene2217	1.241e-145	469.0	COG3842@1|root,COG3842@2|Bacteria,2NNU0@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE
LZS2_k127_3748133_7	1128421.JAGA01000001_gene2218	1.064e-135	440.0	COG3842@1|root,COG3842@2|Bacteria,2NNU0@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	smoK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
LZS2_k127_3748133_11	1128421.JAGA01000001_gene2219	3.676e-100	333.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
LZS2_k127_3748133_14	1122179.KB890497_gene2812	2.267e-20	94.0	2C85M@1|root,32YBZ@2|Bacteria,4NX7M@976|Bacteroidetes	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
LZS2_k127_3748133_5	1089550.ATTH01000001_gene1655	5.389e-154	497.0	COG5441@1|root,COG5441@2|Bacteria,4NHS7@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
LZS2_k127_3748133_4	1304865.JAGF01000001_gene2487	2.607e-157	503.0	COG0673@1|root,COG0673@2|Bacteria,2GNEM@201174|Actinobacteria	201174|Actinobacteria	G	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS2_k127_3748133_2	525904.Tter_0155	2.949e-174	552.0	COG1082@1|root,COG1082@2|Bacteria,2NQCG@2323|unclassified Bacteria	2|Bacteria	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
LZS2_k127_3748133_12	428125.CLOLEP_03155	1.588e-30	128.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia	186801|Clostridia	G	family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
LZS2_k127_3748133_15	1227739.Hsw_0471	2.474e-15	76.0	COG0491@1|root,COG0491@2|Bacteria,4NE2Y@976|Bacteroidetes,47PA3@768503|Cytophagia	976|Bacteroidetes	P	PFAM Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_3748140_0	926550.CLDAP_11940	5.682e-57	214.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_3748140_1	926550.CLDAP_11930	6.097e-19	98.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3,PTPS_related
LZS2_k127_3752756_4	383372.Rcas_1765	1.483e-44	172.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia	32061|Chloroflexia	MV	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
LZS2_k127_3752756_8	926569.ANT_19040	1.396e-14	79.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3752756_1	765420.OSCT_2256	6.628e-116	394.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi,3756H@32061|Chloroflexia	32061|Chloroflexia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
LZS2_k127_3752756_5	1382306.JNIM01000001_gene2753	2.166e-24	104.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi	200795|Chloroflexi	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
LZS2_k127_3752756_0	1408424.JHYI01000001_gene1952	1.311e-199	640.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,1ZBWA@1386|Bacillus	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
LZS2_k127_3752756_6	1125863.JAFN01000001_gene1431	8.476e-24	105.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42VQ6@68525|delta/epsilon subdivisions,2WRTU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
LZS2_k127_3752756_2	485913.Krac_11250	6.956e-76	264.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
LZS2_k127_3752756_3	357808.RoseRS_3756	6.072e-74	259.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,374TG@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM riboflavin biosynthesis protein RibF	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
LZS2_k127_3752756_7	1183438.GKIL_0804	1.474e-21	106.0	COG0500@1|root,COG2226@2|Bacteria,1G0IS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family	-	-	2.1.1.95	ko:K05928	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07236,R07504,R10491,R10492	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
LZS2_k127_3754006_9	1304872.JAGC01000003_gene3411	3.684e-11	66.0	COG0577@1|root,COG0577@2|Bacteria,1Q7A1@1224|Proteobacteria,436MA@68525|delta/epsilon subdivisions,2X18I@28221|Deltaproteobacteria,2MEGT@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS2_k127_3754006_0	926550.CLDAP_25020	6.718e-155	495.0	COG3458@1|root,COG3458@2|Bacteria,2G5R9@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Acetyl xylan esterase	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
LZS2_k127_3754006_1	1049564.TevJSym_ac01750	5.642e-128	414.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1J5NQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
LZS2_k127_3754006_8	926550.CLDAP_32540	8.162e-33	134.0	COG1765@1|root,COG1765@2|Bacteria,2G978@200795|Chloroflexi	200795|Chloroflexi	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
LZS2_k127_3754006_5	1052684.PPM_3089	2.66e-72	252.0	COG1396@1|root,COG1396@2|Bacteria,1TSJ6@1239|Firmicutes,4HC63@91061|Bacilli,26URX@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
LZS2_k127_3754006_4	86416.Clopa_4002	2.087e-81	278.0	COG0500@1|root,COG0500@2|Bacteria,1UI8I@1239|Firmicutes,25EDX@186801|Clostridia,36NV2@31979|Clostridiaceae	186801|Clostridia	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12
LZS2_k127_3754006_2	1123242.JH636435_gene2358	2.067e-103	342.0	COG0500@1|root,COG2226@2|Bacteria,2IYMY@203682|Planctomycetes	203682|Planctomycetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_3754006_3	523850.TON_1355	9.965e-89	307.0	COG1404@1|root,arCOG00702@2157|Archaea,2XTGN@28890|Euryarchaeota,24359@183968|Thermococci	183968|Thermococci	O	Serine protease with a broad substrate specificity	-	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PPC,Peptidase_S8
LZS2_k127_3754006_6	1121121.KB894296_gene681	5.398e-65	252.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,26TP2@186822|Paenibacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_3754006_7	272134.KB731324_gene5476	9.362e-39	145.0	COG2343@1|root,COG2343@2|Bacteria,1G7U6@1117|Cyanobacteria,1HC91@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG2343 conserved	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
LZS2_k127_3769477_7	420324.KI911965_gene529	1.524e-27	116.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2UEWV@28211|Alphaproteobacteria,1JUKY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_3769477_2	1173026.Glo7428_2690	2.417e-90	306.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_3769477_9	272134.KB731324_gene5029	2.013e-24	111.0	COG1011@1|root,COG1011@2|Bacteria,1G51I@1117|Cyanobacteria,1HARR@1150|Oscillatoriales	1117|Cyanobacteria	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
LZS2_k127_3769477_8	926569.ANT_18860	2.936e-25	113.0	COG3743@1|root,COG3743@2|Bacteria,2G96D@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
LZS2_k127_3769477_6	383372.Rcas_4057	2.275e-29	121.0	COG2127@1|root,COG2127@2|Bacteria,2G9F8@200795|Chloroflexi,375WT@32061|Chloroflexia	32061|Chloroflexia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
LZS2_k127_3769477_10	926550.CLDAP_31830	3.188e-20	102.0	COG0457@1|root,COG0457@2|Bacteria,2G9JR@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS2_k127_3769477_0	998674.ATTE01000001_gene3746	7.622e-219	690.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,460BY@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
LZS2_k127_3769477_1	926569.ANT_19910	1.47e-96	326.0	COG3407@1|root,COG3407@2|Bacteria,2G5SQ@200795|Chloroflexi	200795|Chloroflexi	I	GHMP kinases N terminal domain	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
LZS2_k127_3769477_3	926550.CLDAP_05590	8.778e-74	269.0	COG0750@1|root,COG0750@2|Bacteria,2G6GY@200795|Chloroflexi	200795|Chloroflexi	M	SMART PDZ DHR GLGF domain protein	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
LZS2_k127_3769477_11	765420.OSCT_2574	0.0008567	50.0	COG0143@1|root,COG0143@2|Bacteria,2G6VG@200795|Chloroflexi,375Q2@32061|Chloroflexia	32061|Chloroflexia	J	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
LZS2_k127_3769477_5	1382356.JQMP01000001_gene988	2.422e-51	194.0	COG1413@1|root,COG1413@2|Bacteria,2G6MW@200795|Chloroflexi,27Y7K@189775|Thermomicrobia	189775|Thermomicrobia	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
LZS2_k127_3769477_4	357808.RoseRS_0520	2.594e-64	231.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2GAA9@200795|Chloroflexi,376WV@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
LZS2_k127_377827_3	340177.Cag_0951	2.378e-07	55.0	COG3381@1|root,COG3381@2|Bacteria,1FF60@1090|Chlorobi	1090|Chlorobi	S	PFAM cytoplasmic chaperone TorD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
LZS2_k127_377827_2	671143.DAMO_0767	6.226e-17	87.0	COG0723@1|root,COG0723@2|Bacteria,2NRUZ@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
LZS2_k127_377827_0	913865.DOT_4633	4.647e-72	260.0	COG3303@1|root,COG3303@2|Bacteria,1VTAV@1239|Firmicutes,24ZND@186801|Clostridia,264N1@186807|Peptococcaceae	186801|Clostridia	P	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_377827_1	765420.OSCT_2993	1.101e-67	244.0	COG1290@1|root,COG1290@2|Bacteria,2G7XY@200795|Chloroflexi,377D3@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
LZS2_k127_379740_0	1167006.UWK_01323	2.795e-114	371.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_379740_1	926550.CLDAP_19300	5.033e-102	338.0	COG0549@1|root,COG0549@2|Bacteria,2G6C7@200795|Chloroflexi	200795|Chloroflexi	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS2_k127_3802901_6	926569.ANT_10520	3.913e-34	139.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
LZS2_k127_3802901_11	1128421.JAGA01000002_gene540	3.755e-15	78.0	COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria	2|Bacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
LZS2_k127_3802901_10	1410670.JHXF01000006_gene1097	8.304e-19	92.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,3WKJC@541000|Ruminococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
LZS2_k127_3802901_9	871968.DESME_15470	2.211e-19	94.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,261U6@186807|Peptococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
LZS2_k127_3802901_1	525904.Tter_0065	2.294e-217	685.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS2_k127_3802901_4	1128421.JAGA01000002_gene544	5.506e-82	282.0	COG0224@1|root,COG0224@2|Bacteria,2NP76@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
LZS2_k127_3802901_0	479434.Sthe_1421	1.824e-230	720.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi,27XYE@189775|Thermomicrobia	189775|Thermomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS2_k127_3802901_7	383372.Rcas_1264	7.329e-32	129.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi,375QG@32061|Chloroflexia	32061|Chloroflexia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
LZS2_k127_3802901_2	1382356.JQMP01000003_gene1994	1.079e-126	413.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,27Y3P@189775|Thermomicrobia	189775|Thermomicrobia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
LZS2_k127_3802901_5	926569.ANT_13820	1.044e-68	239.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi	200795|Chloroflexi	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
LZS2_k127_3802901_12	536227.CcarbDRAFT_1486	7.811e-06	56.0	2B2EX@1|root,31UZJ@2|Bacteria,1V7U1@1239|Firmicutes,24K8B@186801|Clostridia,36GWN@31979|Clostridiaceae	186801|Clostridia	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
LZS2_k127_3802901_8	316274.Haur_1602	1.239e-27	128.0	COG0845@1|root,COG0845@2|Bacteria,2G8US@200795|Chloroflexi,3771R@32061|Chloroflexia	32061|Chloroflexia	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
LZS2_k127_3802901_3	926550.CLDAP_19390	1.185e-86	291.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_3803703_0	926550.CLDAP_20060	1.507e-142	479.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
LZS2_k127_3803703_1	926550.CLDAP_30360	1.51e-118	412.0	COG3391@1|root,COG5305@1|root,COG3391@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_3813806_4	926550.CLDAP_21420	8.071e-06	55.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
LZS2_k127_3813806_1	429009.Adeg_0218	5.54e-44	166.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,1TQH8@1239|Firmicutes,2491Q@186801|Clostridia,42IIF@68295|Thermoanaerobacterales	186801|Clostridia	S	AMMECR1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
LZS2_k127_3813806_0	525904.Tter_1028	1.908e-65	237.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314,ko:K02316,ko:K17680	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03029,ko03032	-	-	-	DnaB_C,Toprim_2,Toprim_N,zf-CHC2
LZS2_k127_3813806_2	765420.OSCT_1795	1.671e-37	148.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_3813806_3	429009.Adeg_0923	1.714e-29	125.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia,42JBW@68295|Thermoanaerobacterales	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS2_k127_3834497_4	468059.AUHA01000003_gene1412	8.403e-59	209.0	COG0262@1|root,COG0262@2|Bacteria,4NQ2Y@976|Bacteroidetes,1ISYU@117747|Sphingobacteriia	976|Bacteroidetes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	2TM,DHFR_1
LZS2_k127_3834497_3	523850.TON_0392	3.316e-90	312.0	COG0043@1|root,arCOG01671@2157|Archaea,2XUDW@28890|Euryarchaeota,242S6@183968|Thermococci	183968|Thermococci	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
LZS2_k127_3834497_2	523845.AQXV01000015_gene369	4.402e-104	351.0	COG1679@1|root,arCOG04278@2157|Archaea,2XTY6@28890|Euryarchaeota,23QFZ@183939|Methanococci	183939|Methanococci	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
LZS2_k127_3834497_5	1041930.Mtc_1230	3.705e-37	143.0	COG1786@1|root,arCOG04279@2157|Archaea,2XYXJ@28890|Euryarchaeota,2N9R7@224756|Methanomicrobia	224756|Methanomicrobia	C	Belongs to the UPF0107 family	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
LZS2_k127_3834497_1	309799.DICTH_1692	1.353e-105	371.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	bmnA	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
LZS2_k127_3834497_0	926550.CLDAP_11790	2.448e-238	771.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
LZS2_k127_3888770_0	903818.KI912268_gene806	0.0	2169.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,3Y2JQ@57723|Acidobacteria	57723|Acidobacteria	E	glutamate synthase alpha subunit	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
LZS2_k127_3888770_1	903818.KI912268_gene805	4.194e-205	646.0	COG0493@1|root,COG0493@2|Bacteria,3Y2JM@57723|Acidobacteria	57723|Acidobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
LZS2_k127_3893848_2	926550.CLDAP_39360	9.251e-25	109.0	COG3118@1|root,COG3118@2|Bacteria,2G70B@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function (DUF2892)	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	DUF2892,Thioredoxin
LZS2_k127_3893848_0	324602.Caur_1860	4.348e-41	158.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
LZS2_k127_3893848_3	479434.Sthe_3344	9.675e-23	106.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS2_k127_3893848_1	926550.CLDAP_02220	3.351e-30	127.0	COG2335@1|root,COG2335@2|Bacteria	2|Bacteria	M	COG2335, Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
LZS2_k127_3893848_6	709986.Deima_1555	0.0001232	53.0	COG2010@1|root,COG2010@2|Bacteria,1WIF2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS2_k127_3893848_7	394221.Mmar10_0196	0.0004649	49.0	COG4244@1|root,COG4244@2|Bacteria,1NACQ@1224|Proteobacteria,2UHJX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3893848_4	497964.CfE428DRAFT_0238	2.012e-16	87.0	COG2010@1|root,COG2010@2|Bacteria,46TSG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
LZS2_k127_3894301_1	195253.Syn6312_2305	2.7e-24	109.0	COG1357@1|root,COG1357@2|Bacteria,1G42W@1117|Cyanobacteria,1GYZ1@1129|Synechococcus	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_3894301_0	1499967.BAYZ01000061_gene5932	9.322e-82	288.0	COG0438@1|root,COG0438@2|Bacteria,2NNTN@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_3894301_2	383372.Rcas_1047	1.522e-14	88.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
LZS2_k127_3894301_3	383372.Rcas_0849	1.362e-11	74.0	COG1807@1|root,COG1807@2|Bacteria,2GAPY@200795|Chloroflexi,376ZD@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_3895687_1	484770.UFO1_1182	3.302e-90	304.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_3895687_0	383372.Rcas_2537	3.167e-202	657.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_3895687_2	926550.CLDAP_23630	1.215e-46	175.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_3895687_3	926550.CLDAP_29890	5.73e-25	108.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
LZS2_k127_39055_2	649747.HMPREF0083_03979	8.923e-06	53.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli,26R6H@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
LZS2_k127_39055_3	1125725.HMPREF1325_0668	0.0005123	43.0	COG1082@1|root,COG1082@2|Bacteria,2J8EP@203691|Spirochaetes	203691|Spirochaetes	G	TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
LZS2_k127_39055_1	1123508.JH636440_gene1975	7.073e-46	180.0	COG0524@1|root,COG0524@2|Bacteria,2IWUH@203682|Planctomycetes	203682|Planctomycetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
LZS2_k127_39055_0	1123508.JH636447_gene7942	3.059e-69	241.0	COG0800@1|root,COG0800@2|Bacteria,2IXBP@203682|Planctomycetes	203682|Planctomycetes	G	PFAM KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
LZS2_k127_3917228_0	926569.ANT_19800	3.537e-116	391.0	COG0210@1|root,COG0210@2|Bacteria,2G7VU@200795|Chloroflexi	200795|Chloroflexi	F	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3917228_1	926569.ANT_19790	4.036e-48	181.0	COG0210@1|root,COG0210@2|Bacteria,2G86J@200795|Chloroflexi	200795|Chloroflexi	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS2_k127_3926901_0	324602.Caur_1269	3.274e-97	337.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2G8ES@200795|Chloroflexi,3759V@32061|Chloroflexia	32061|Chloroflexia	P	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
LZS2_k127_3933064_0	525904.Tter_2643	1.632e-60	229.0	2APCB@1|root,31EEJ@2|Bacteria,2NRJG@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
LZS2_k127_3944982_2	926550.CLDAP_02930	8.038e-109	361.0	COG1609@1|root,COG1609@2|Bacteria,2G675@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_3944982_0	926569.ANT_28600	7.71e-171	548.0	COG1653@1|root,COG1653@2|Bacteria,2G72Y@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1
LZS2_k127_3944982_3	926569.ANT_28590	3.491e-89	303.0	COG1175@1|root,COG1175@2|Bacteria,2G8B0@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
LZS2_k127_3944982_4	1128421.JAGA01000003_gene3328	1.218e-86	295.0	COG0395@1|root,COG0395@2|Bacteria,2NQJI@2323|unclassified Bacteria	2|Bacteria	G	Binding-protein-dependent transport system inner membrane component	MA20_14020	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
LZS2_k127_3944982_1	926569.ANT_28570	4.743e-141	454.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM_2,Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
LZS2_k127_394601_4	1173028.ANKO01000106_gene313	1.689e-27	116.0	COG0515@1|root,COG1357@1|root,COG0515@2|Bacteria,COG1357@2|Bacteria,1G08U@1117|Cyanobacteria,1H85Z@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pkinase
LZS2_k127_394601_1	926550.CLDAP_20970	4.548e-69	243.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_394601_2	443143.GM18_4005	1.698e-31	128.0	COG0745@1|root,COG3437@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
LZS2_k127_394601_0	926550.CLDAP_20900	8.986e-248	773.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
LZS2_k127_394601_3	926550.CLDAP_21560	6.644e-28	118.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_395637_1	926550.CLDAP_05320	2.511e-94	315.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
LZS2_k127_395637_0	926550.CLDAP_23260	5.381e-186	608.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,STT3
LZS2_k127_3958268_3	269482.Bcep1808_4124	4.325e-22	98.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VQF1@28216|Betaproteobacteria,1K5UV@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
LZS2_k127_3958268_0	926550.CLDAP_32450	1.003e-219	691.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	2|Bacteria	G	PFAM carbohydrate kinase	-	-	2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5	ko:K00848,ko:K00851,ko:K00854,ko:K00862	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
LZS2_k127_3958268_1	926550.CLDAP_32440	1.63e-133	434.0	COG1063@1|root,COG1063@2|Bacteria,2G6PM@200795|Chloroflexi	200795|Chloroflexi	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_3958268_2	926550.CLDAP_32280	3.452e-109	361.0	COG2390@1|root,COG2390@2|Bacteria,2G8CS@200795|Chloroflexi	200795|Chloroflexi	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sugar-bind
LZS2_k127_3975059_0	460265.Mnod_2431	1.302e-62	226.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_3975059_2	557599.MKAN_22200	1.621e-34	140.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria	201174|Actinobacteria	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_3975059_5	1122925.KB895403_gene166	1.156e-31	133.0	COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,4HKAT@91061|Bacilli,26SSW@186822|Paenibacillaceae	91061|Bacilli	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA3	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
LZS2_k127_3975059_1	880073.Calab_2721	2.363e-45	174.0	COG0688@1|root,COG0688@2|Bacteria,2NPRX@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
LZS2_k127_3975059_6	1382304.JNIL01000001_gene203	3.572e-31	130.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli,278J6@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
LZS2_k127_3975059_4	1382356.JQMP01000003_gene1852	2.502e-32	131.0	COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi,27YJD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
LZS2_k127_3975059_3	926569.ANT_25140	9.465e-34	135.0	COG0202@1|root,COG0254@1|root,COG0202@2|Bacteria,COG0254@2|Bacteria,2G75A@200795|Chloroflexi	200795|Chloroflexi	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
LZS2_k127_3992201_0	926569.ANT_25700	5.385e-187	634.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS2_k127_3992201_1	926550.CLDAP_31870	2.434e-86	290.0	COG0205@1|root,COG0205@2|Bacteria,2G5XX@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS2_k127_3994313_6	926569.ANT_30960	7.718e-25	106.0	COG1951@1|root,COG1951@2|Bacteria,2G6YI@200795|Chloroflexi	200795|Chloroflexi	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2	ko:K01676,ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
LZS2_k127_3994313_5	1121381.JNIV01000044_gene1810	1.299e-40	156.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HIT
LZS2_k127_3994313_2	479434.Sthe_2201	4.141e-62	221.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS2_k127_3994313_3	926550.CLDAP_18190	3.724e-43	162.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
LZS2_k127_3994313_0	357808.RoseRS_1482	1.083e-98	334.0	COG1057@1|root,COG1057@2|Bacteria,2GASF@200795|Chloroflexi,3777U@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3994313_7	945713.IALB_2163	2.612e-13	81.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
LZS2_k127_3994313_1	1121346.KB899816_gene3303	1.555e-87	312.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,26QGU@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	oppA	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
LZS2_k127_3994313_9	118168.MC7420_6824	0.0005693	43.0	COG0610@1|root,COG2852@1|root,COG0610@2|Bacteria,COG2852@2|Bacteria,1G3YH@1117|Cyanobacteria,1HA5G@1150|Oscillatoriales	1117|Cyanobacteria	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
LZS2_k127_3994313_4	359.CN09_26120	6.981e-43	168.0	COG0524@1|root,COG0524@2|Bacteria,1N97R@1224|Proteobacteria,2UNRH@28211|Alphaproteobacteria,4BCXX@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS2_k127_4045326_4	926569.ANT_22420	5.012e-50	181.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS2_k127_4045326_7	264732.Moth_0128	6.257e-23	102.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,42GUD@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
LZS2_k127_4045326_1	1232410.KI421426_gene1487	5.389e-164	529.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,43T0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
LZS2_k127_4045326_0	555079.Toce_0594	2.967e-164	525.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,42F24@68295|Thermoanaerobacterales	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
LZS2_k127_4045326_2	986075.CathTA2_2027	1.027e-93	314.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
LZS2_k127_4045326_3	1333523.L593_00550	1.753e-51	187.0	COG4803@1|root,arCOG05227@2157|Archaea,2XXG6@28890|Euryarchaeota,23VR0@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
LZS2_k127_4045326_6	103690.17130275	2.718e-26	112.0	COG0745@1|root,COG0745@2|Bacteria,1G5PY@1117|Cyanobacteria,1HN81@1161|Nostocales	1117|Cyanobacteria	KT	PFAM response regulator receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
LZS2_k127_4045326_5	2325.TKV_c07320	3.003e-45	175.0	COG0671@1|root,COG0671@2|Bacteria,1V01Y@1239|Firmicutes,24DFI@186801|Clostridia,42FMS@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
LZS2_k127_4045326_8	1042877.GQS_09775	8.185e-22	111.0	arCOG08791@1|root,arCOG08791@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4045326_9	1480694.DC28_01035	3.509e-16	87.0	COG1437@1|root,COG1437@2|Bacteria,2J8S7@203691|Spirochaetes	203691|Spirochaetes	F	CYTH domain	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
LZS2_k127_4045326_10	626887.J057_02250	4.589e-05	53.0	COG1807@1|root,COG1807@2|Bacteria,1MXH5@1224|Proteobacteria,1RSQE@1236|Gammaproteobacteria,464KM@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_4050691_11	926569.ANT_10920	5.004e-20	92.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
LZS2_k127_4050691_10	765420.OSCT_2975	3.284e-23	101.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi,375YB@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
LZS2_k127_4050691_2	357808.RoseRS_2549	6.806e-159	512.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi,376TA@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_4050691_6	926550.CLDAP_31390	6.072e-128	428.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926550.CLDAP_31390|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4050691_8	316067.Geob_0046	2.661e-54	199.0	COG2197@1|root,COG2197@2|Bacteria,1QWB3@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_4050691_7	313612.L8106_15315	2.593e-89	312.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1G35U@1117|Cyanobacteria,1H78M@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF4118,GAF_3,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_4050691_12	530564.Psta_2823	9.178e-06	50.0	2DTD4@1|root,33JTG@2|Bacteria,2J4JM@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4050691_5	926550.CLDAP_24880	4.461e-154	495.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
LZS2_k127_4050691_1	926569.ANT_22690	9.252e-224	709.0	COG1132@1|root,COG1132@2|Bacteria,2G7KM@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_4050691_0	926569.ANT_22700	3.254e-247	776.0	COG1132@1|root,COG1132@2|Bacteria,2G7KA@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_4050691_4	666686.B1NLA3E_08560	2.396e-156	502.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli,1ZBQE@1386|Bacillus	91061|Bacilli	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
LZS2_k127_4050691_9	504728.K649_08795	6.451e-37	144.0	COG1522@1|root,COG1522@2|Bacteria,1WN04@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
LZS2_k127_4050691_3	1484460.JSWG01000015_gene1125	2.31e-157	503.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_4051031_3	357808.RoseRS_2247	1.312e-54	199.0	COG1608@1|root,COG1608@2|Bacteria,2G6TH@200795|Chloroflexi,376UF@32061|Chloroflexia	32061|Chloroflexia	F	Amino acid kinase family	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS2_k127_4051031_6	926550.CLDAP_21430	1.696e-30	139.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
LZS2_k127_4051031_1	525904.Tter_2844	2.558e-74	259.0	COG1192@1|root,COG1192@2|Bacteria,2NQVW@2323|unclassified Bacteria	2|Bacteria	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS2_k127_4051031_4	765420.OSCT_1680	3.259e-49	185.0	COG1192@1|root,COG1192@2|Bacteria,2G8YP@200795|Chloroflexi,374WY@32061|Chloroflexia	32061|Chloroflexia	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS2_k127_4051031_5	926550.CLDAP_11900	1.137e-36	160.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_4051031_0	926550.CLDAP_21440	3.472e-116	404.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_4051031_2	485913.Krac_8091	4.733e-67	238.0	COG3393@1|root,COG3393@2|Bacteria,2G8JB@200795|Chloroflexi	200795|Chloroflexi	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
LZS2_k127_4051031_7	357808.RoseRS_0410	1.856e-16	87.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
LZS2_k127_4059599_1	644076.SCH4B_3410	1.538e-19	89.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TS0W@28211|Alphaproteobacteria,4NAHS@97050|Ruegeria	28211|Alphaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_4059599_0	926550.CLDAP_32670	1.193e-136	453.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS2_k127_4059599_2	443255.SCLAV_2188	5.673e-19	92.0	COG4043@1|root,COG4043@2|Bacteria,2IMD7@201174|Actinobacteria	201174|Actinobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
LZS2_k127_4077487_3	316274.Haur_3927	1.357e-43	169.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi,375FI@32061|Chloroflexia	32061|Chloroflexia	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
LZS2_k127_4077487_7	324057.Pjdr2_5552	2.424e-05	55.0	2DZXU@1|root,32VMR@2|Bacteria,1VBBV@1239|Firmicutes,4HPWN@91061|Bacilli,26ZA3@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4077487_0	765420.OSCT_2993	2.687e-130	431.0	COG1290@1|root,COG1290@2|Bacteria,2G7XY@200795|Chloroflexi,377D3@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
LZS2_k127_4077487_2	765420.OSCT_2992	3.701e-51	186.0	COG0723@1|root,COG0723@2|Bacteria,2GB28@200795|Chloroflexi,377SJ@32061|Chloroflexia	32061|Chloroflexia	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
LZS2_k127_4077487_1	765420.OSCT_2991	2.229e-90	310.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0098822,GO:1901363,GO:1901564	1.8.2.2	ko:K00406,ko:K03889,ko:K17222,ko:K19713	ko00190,ko00920,ko01100,ko01120,ko02020,map00190,map00920,map01100,map01120,map02020	M00151,M00156,M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3
LZS2_k127_4077487_4	926569.ANT_00760	3.082e-34	139.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
LZS2_k127_4078874_4	545694.TREPR_2179	8.034e-26	111.0	COG4231@1|root,COG4231@2|Bacteria	2|Bacteria	C	indolepyruvate ferredoxin oxidoreductase activity	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
LZS2_k127_4078874_3	485913.Krac_0674	5.555e-65	230.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
LZS2_k127_4078874_0	452637.Oter_4342	5.949e-148	475.0	COG1312@1|root,COG1312@2|Bacteria,46UDP@74201|Verrucomicrobia,3K8B6@414999|Opitutae	414999|Opitutae	G	Catalyzes the dehydration of D-mannonate	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
LZS2_k127_4078874_1	452637.Oter_4331	2.202e-85	290.0	COG1028@1|root,COG1028@2|Bacteria,46YNC@74201|Verrucomicrobia,3K7SX@414999|Opitutae	414999|Opitutae	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
LZS2_k127_4078874_2	215803.DB30_7634	6.625e-80	276.0	COG2378@1|root,COG2378@2|Bacteria,1PXCX@1224|Proteobacteria,42V48@68525|delta/epsilon subdivisions,2WPJT@28221|Deltaproteobacteria,2YTT4@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Deoxyribose operon repressor	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
LZS2_k127_4083063_0	1242864.D187_003184	5.05e-128	430.0	COG0457@1|root,COG0457@2|Bacteria	1242864.D187_003184|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4083063_2	316274.Haur_0080	5.023e-67	241.0	COG0726@1|root,COG0726@2|Bacteria,2G8CG@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS2_k127_4083063_1	316274.Haur_0080	1.808e-70	252.0	COG0726@1|root,COG0726@2|Bacteria,2G8CG@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS2_k127_4083063_3	886293.Sinac_7551	5.663e-52	188.0	COG0491@1|root,COG0491@2|Bacteria,2J4KU@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_4085379_13	649747.HMPREF0083_00352	0.0001693	51.0	COG3118@1|root,COG3118@2|Bacteria,1UMIW@1239|Firmicutes,4ITWC@91061|Bacilli,277EQ@186822|Paenibacillaceae	91061|Bacilli	O	belongs to the thioredoxin family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4085379_5	926550.CLDAP_16410	5.478e-86	295.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1385)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
LZS2_k127_4085379_9	357808.RoseRS_1951	6.685e-14	85.0	COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4085379_12	1101195.Meth11DRAFT_0026	4.787e-06	59.0	COG0457@1|root,COG3914@1|root,COG4421@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,COG4421@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,2KMDJ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Glycosyltransferase like family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glyco_transf_41,Methyltransf_12,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_4085379_7	1229172.JQFA01000002_gene4125	1.758e-33	139.0	COG0705@1|root,COG0705@2|Bacteria,1FZY1@1117|Cyanobacteria,1H9IP@1150|Oscillatoriales	1117|Cyanobacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS2_k127_4085379_2	926550.CLDAP_38550	1.38e-139	462.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_4085379_10	243164.DET1549	7.072e-11	65.0	COG1314@1|root,COG1314@2|Bacteria,2G7D9@200795|Chloroflexi,34DHN@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
LZS2_k127_4085379_0	671143.DAMO_2604	3.284e-178	576.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS2_k127_4085379_4	483219.LILAB_20340	3.455e-92	316.0	COG0604@1|root,COG0604@2|Bacteria,1MW2V@1224|Proteobacteria,433WU@68525|delta/epsilon subdivisions,2X2BB@28221|Deltaproteobacteria,2YXH4@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_4085379_8	926550.CLDAP_15390	2.052e-26	117.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS2_k127_4085379_14	926569.ANT_23670	0.0009869	44.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS2_k127_4085379_1	926550.CLDAP_15430	2.901e-169	539.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
LZS2_k127_4085379_3	138119.DSY0869	8.167e-94	315.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,261MU@186807|Peptococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
LZS2_k127_4085379_6	767817.Desgi_3970	4.323e-42	164.0	COG0740@1|root,COG0740@2|Bacteria,1UKGT@1239|Firmicutes,25FWY@186801|Clostridia	186801|Clostridia	OU	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4088157_4	56110.Oscil6304_1417	3.678e-34	139.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	hglK	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_4088157_5	498848.TaqDRAFT_3562	3.554e-29	124.0	COG0344@1|root,COG0344@2|Bacteria,1WJ35@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
LZS2_k127_4088157_2	926550.CLDAP_12510	3.834e-65	235.0	COG0613@1|root,COG0613@2|Bacteria,2G6H4@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
LZS2_k127_4088157_1	1499967.BAYZ01000009_gene5348	4.161e-74	255.0	COG1428@1|root,COG1428@2|Bacteria,2NR23@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
LZS2_k127_4088157_0	326427.Cagg_1592	1.665e-98	334.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_4088157_6	640081.Dsui_1000	7.895e-29	130.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS2_k127_4088157_3	1173264.KI913949_gene4306	4.741e-54	209.0	COG1305@1|root,COG1305@2|Bacteria,1FZW2@1117|Cyanobacteria,1H7X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
LZS2_k127_4088157_7	697284.ERIC2_c10220	2.362e-08	63.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,26SAZ@186822|Paenibacillaceae	91061|Bacilli	E	transglutaminase	yebA3	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
LZS2_k127_4094183_3	1049564.TevJSym_ac01700	3.638e-70	247.0	COG5607@1|root,COG5607@2|Bacteria,1R5I1@1224|Proteobacteria,1S0QK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	pfam chad	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,His_Phos_1
LZS2_k127_4094183_4	1121403.AUCV01000003_gene1785	2.19e-69	244.0	COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria	1224|Proteobacteria	D	involved in chromosome partitioning	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS2_k127_4094183_5	485915.Dret_2352	3.1e-39	155.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	Abi
LZS2_k127_4094183_7	1499967.BAYZ01000177_gene5750	2.273e-23	106.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	rplU	-	-	ko:K02879,ko:K02888,ko:K02890,ko:K02899,ko:K02967,ko:K04074	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03036	-	-	-	HHH_5,Ribosomal_L21p
LZS2_k127_4094183_6	870187.Thini_4361	7.774e-30	123.0	COG2105@1|root,COG2105@2|Bacteria,1NEI1@1224|Proteobacteria,1SDSK@1236|Gammaproteobacteria,463F3@72273|Thiotrichales	72273|Thiotrichales	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4094183_2	765420.OSCT_0147	3.077e-77	265.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi,375AH@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
LZS2_k127_4094183_0	880073.Calab_2597	6.89e-184	587.0	COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c	DALR_2,tRNA-synt_1e,tRNA-synt_1g
LZS2_k127_4094183_1	926569.ANT_30570	2.319e-112	373.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
LZS2_k127_4203434_1	479434.Sthe_2638	3.402e-45	168.0	COG2606@1|root,COG2606@2|Bacteria,2G6MD@200795|Chloroflexi,27Z83@189775|Thermomicrobia	189775|Thermomicrobia	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
LZS2_k127_4203434_0	926550.CLDAP_31310	1.66e-129	420.0	COG0119@1|root,COG0119@2|Bacteria,2G5KT@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
LZS2_k127_4221973_0	1122963.AUHB01000001_gene328	0.0	1305.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,36Y2W@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
LZS2_k127_4221973_1	649639.Bcell_2329	0.0	1174.0	COG3459@1|root,COG3459@2|Bacteria,1TVMK@1239|Firmicutes,4H9ZP@91061|Bacilli,1ZF4F@1386|Bacillus	91061|Bacilli	G	Glycosyl hydrolase 36 superfamily, catalytic domain	chvB1	-	2.4.1.20,2.4.1.333	ko:K00702,ko:K13688,ko:K21298	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36
LZS2_k127_4221973_4	1193181.BN10_680049	2.116e-52	203.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FFZE@85021|Intrasporangiaceae	201174|Actinobacteria	EGP	Major facilitator superfamily	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_4221973_3	525904.Tter_2656	2.052e-112	376.0	COG1940@1|root,COG1940@2|Bacteria,2NPF7@2323|unclassified Bacteria	2|Bacteria	GK	Sugar kinase of the NBD HSP70 family, may containing an N-terminal HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR,MarR_2,ROK
LZS2_k127_4221973_2	926569.ANT_05060	9.381e-157	500.0	COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
LZS2_k127_4224027_3	1304284.L21TH_0060	0.0009593	44.0	2DTYV@1|root,33N9C@2|Bacteria,1VPKU@1239|Firmicutes,251U2@186801|Clostridia,36SAU@31979|Clostridiaceae	186801|Clostridia	S	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4224027_1	324602.Caur_2958	2.593e-59	229.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_4224027_0	357808.RoseRS_2826	1.721e-132	447.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
LZS2_k127_4224027_2	1121468.AUBR01000034_gene1374	2.794e-08	56.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS2_k127_4241391_0	373903.Hore_09960	1.929e-76	280.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WAHY@53433|Halanaerobiales	186801|Clostridia	T	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_4260019_2	314271.RB2654_20938	3.473e-11	63.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2TSTD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS2_k127_4260019_1	316274.Haur_1215	1.532e-33	134.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K02030,ko:K03407,ko:K07679,ko:K11443,ko:K13924	ko02020,ko02030,ko04112,ko05133,map02020,map02030,map04112,map05133	M00236,M00477,M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	3.A.1.3	-	-	CHASE3,HATPase_c,HisKA,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
LZS2_k127_4260019_0	316274.Haur_1216	1.257e-50	190.0	COG0454@1|root,COG0456@2|Bacteria,2G9FH@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_4283185_1	485913.Krac_8486	9.224e-55	201.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
LZS2_k127_4283185_2	309801.trd_0089	3.237e-17	82.0	COG0227@1|root,COG0227@2|Bacteria,2G9W5@200795|Chloroflexi,27Z9I@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal L28 family	-	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
LZS2_k127_4283185_0	926569.ANT_16630	4.148e-114	378.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
LZS2_k127_4325887_5	368407.Memar_1051	4.807e-06	51.0	COG3187@1|root,arCOG03952@2157|Archaea,2Y55P@28890|Euryarchaeota,2NBFA@224756|Methanomicrobia	224756|Methanomicrobia	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
LZS2_k127_4325887_3	926569.ANT_03380	3.319e-33	132.0	COG0239@1|root,COG0239@2|Bacteria,2G760@200795|Chloroflexi	200795|Chloroflexi	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
LZS2_k127_4325887_1	357808.RoseRS_2494	1.3e-92	319.0	COG0517@1|root,COG1993@1|root,COG0517@2|Bacteria,COG1993@2|Bacteria,2G69Z@200795|Chloroflexi,376P4@32061|Chloroflexia	32061|Chloroflexia	T	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF190
LZS2_k127_4325887_0	211165.AJLN01000148_gene2390	6.996e-99	330.0	COG0491@1|root,COG0491@2|Bacteria,1G9C5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
LZS2_k127_4325887_2	357808.RoseRS_2702	1.56e-72	258.0	COG1721@1|root,COG1721@2|Bacteria,2GADH@200795|Chloroflexi,375KE@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS2_k127_4325887_4	1128421.JAGA01000002_gene1759	1.279e-23	107.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
LZS2_k127_436835_1	485913.Krac_8795	1.707e-18	97.0	2E8GM@1|root,332UW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_436835_3	105420.BBPO01000102_gene6322	2.308e-05	56.0	COG1652@1|root,COG1652@2|Bacteria,2I8YV@201174|Actinobacteria,2NG09@228398|Streptacidiphilus	201174|Actinobacteria	K	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,LysM
LZS2_k127_436835_0	1041930.Mtc_1015	2.979e-35	154.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03042@2157|Archaea,2Y7M7@28890|Euryarchaeota,2NBM0@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
LZS2_k127_43771_18	234267.Acid_0494	4.703e-40	153.0	COG4531@1|root,COG4531@2|Bacteria,3Y2X7@57723|Acidobacteria	57723|Acidobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_43771_22	1128421.JAGA01000003_gene2875	1.309e-12	72.0	2EJZ3@1|root,33DPP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_43771_9	886293.Sinac_3660	1.162e-78	272.0	COG1999@1|root,COG1999@2|Bacteria,2IYYD@203682|Planctomycetes	203682|Planctomycetes	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS2_k127_43771_8	1128421.JAGA01000003_gene2877	3.792e-103	343.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2NNSH@2323|unclassified Bacteria	2|Bacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275,ko:K17223	ko00190,ko00920,ko01100,ko01120,map00190,map00920,map01100,map01120	M00155,M00595	R00081,R10151	RC00016,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
LZS2_k127_43771_0	324602.Caur_2142	1.71e-251	786.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,3750X@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
LZS2_k127_43771_10	1128421.JAGA01000003_gene2879	1.865e-69	244.0	COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria	2|Bacteria	C	cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
LZS2_k127_43771_21	1128421.JAGA01000003_gene2880	4.393e-21	96.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
LZS2_k127_43771_7	748247.AZKH_p0076	2.31e-107	355.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VIVI@28216|Betaproteobacteria,2KUVA@206389|Rhodocyclales	28216|Betaproteobacteria	I	2-hydroxy-3-oxopropionate reductase	-	-	1.1.1.31,1.1.1.411	ko:K00020,ko:K08319	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
LZS2_k127_43771_12	232346.JHQL01000001_gene2407	5.042e-67	233.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,1S9CM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
LZS2_k127_43771_11	760568.Desku_1636	8.312e-69	246.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,261SM@186807|Peptococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02525,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
LZS2_k127_43771_2	1463917.JODC01000008_gene3139	4.945e-201	643.0	COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria	201174|Actinobacteria	G	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
LZS2_k127_43771_3	926550.CLDAP_23180	1.064e-190	606.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_43771_6	926550.CLDAP_23190	2.797e-113	376.0	COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_43771_5	926550.CLDAP_23200	3.929e-114	375.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi	2|Bacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_43771_1	485913.Krac_4334	2.388e-244	768.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
LZS2_k127_43771_13	1268240.ATFI01000013_gene1127	1.233e-66	250.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,2FRKH@200643|Bacteroidia,4ARGS@815|Bacteroidaceae	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
LZS2_k127_43771_16	316274.Haur_4640	1.085e-45	170.0	COG4570@1|root,COG4570@2|Bacteria,2G8U7@200795|Chloroflexi	200795|Chloroflexi	L	Endodeoxyribonuclease RusA	-	-	3.1.22.4	ko:K01160	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	RusA
LZS2_k127_43771_14	926550.CLDAP_13220	1.283e-48	183.0	COG1842@1|root,COG1842@2|Bacteria	2|Bacteria	KT	Phage shock protein A	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	Peptidase_M23,PspA_IM30
LZS2_k127_43771_15	485913.Krac_4939	2.223e-46	177.0	COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi	200795|Chloroflexi	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS2_k127_43771_17	926550.CLDAP_01140	5.619e-45	168.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
LZS2_k127_43771_4	760568.Desku_3195	6.709e-166	536.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,260CD@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
LZS2_k127_4392527_1	926569.ANT_14050	1.172e-37	148.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
LZS2_k127_4392527_2	457570.Nther_0587	2.576e-16	91.0	COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes	1239|Firmicutes	S	Acetyltransferase involved in intracellular survival and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
LZS2_k127_4392527_3	1191523.MROS_1248	1.295e-15	78.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS2_k127_4392527_0	926569.ANT_24700	4.048e-108	362.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi	200795|Chloroflexi	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
LZS2_k127_4429772_2	926550.CLDAP_10230	1.164e-24	119.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	3.5.1.104	ko:K21449,ko:K22278	-	-	-	-	ko00000,ko01000,ko02000	1.B.40.2	-	-	LysM,PG_binding_1,PG_binding_4,YkuD
LZS2_k127_4429772_0	324602.Caur_3265	1.146e-73	260.0	COG1266@1|root,COG1266@2|Bacteria,2G76F@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS2_k127_4429772_1	1173027.Mic7113_6391	2.426e-45	170.0	COG2453@1|root,COG2453@2|Bacteria	2|Bacteria	T	phosphatase	-	-	3.1.3.16,3.1.3.48	ko:K04459,ko:K14165	ko04010,map04010	-	-	-	ko00000,ko00001,ko01000,ko01009	-	-	-	DSPc
LZS2_k127_4429843_3	316274.Haur_4082	0.000233	51.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4429843_0	330214.NIDE0497	1.007e-76	287.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,3J0QY@40117|Nitrospirae	40117|Nitrospirae	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS2_k127_4429843_2	694427.Palpr_2946	1.539e-26	113.0	2BFHQ@1|root,329BH@2|Bacteria,4P73M@976|Bacteroidetes,2FZWT@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4429843_1	1499967.BAYZ01000060_gene5985	7.368e-58	222.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,2NR14@2323|unclassified Bacteria	2|Bacteria	U	Patatin-like phospholipase	CP_0464	-	-	ko:K01999,ko:K07001	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Patatin,cNMP_binding
LZS2_k127_4430093_2	697281.Mahau_0940	8.255e-17	80.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,42FF6@68295|Thermoanaerobacterales	186801|Clostridia	L	AAA ATPase, central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
LZS2_k127_4430093_0	1173022.Cri9333_0755	2.138e-275	862.0	COG2256@1|root,COG2256@2|Bacteria,1G36R@1117|Cyanobacteria,1H9UW@1150|Oscillatoriales	1117|Cyanobacteria	L	ATPase family associated with various cellular activities (AAA)	mgs1	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
LZS2_k127_4430093_1	391612.CY0110_21722	2.471e-73	255.0	COG0531@1|root,COG0531@2|Bacteria,1G3K6@1117|Cyanobacteria,3KJMN@43988|Cyanothece	1117|Cyanobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
LZS2_k127_4476202_4	868131.MSWAN_0358	1.979e-43	170.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,23NRH@183925|Methanobacteria	183925|Methanobacteria	M	Bacterial transferase hexapeptide repeat	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS2_k127_4476202_5	485916.Dtox_1956	1.07e-41	161.0	COG1865@1|root,COG1865@2|Bacteria,1TQHV@1239|Firmicutes,24AA4@186801|Clostridia,262A9@186807|Peptococcaceae	186801|Clostridia	S	Adenosylcobinamide amidohydrolase	cbiZ	-	-	-	-	-	-	-	-	-	-	-	CbiZ
LZS2_k127_4476202_2	357808.RoseRS_2125	4.432e-86	299.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,2G7JP@200795|Chloroflexi,374XQ@32061|Chloroflexia	32061|Chloroflexia	K	PFAM AAA-4 family protein	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_DeoR
LZS2_k127_4476202_6	483218.BACPEC_01686	1.885e-05	53.0	2DN9J@1|root,32W95@2|Bacteria,1VEB5@1239|Firmicutes,24Q13@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
LZS2_k127_4476202_0	357808.RoseRS_1605	1.775e-299	938.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,374Z8@32061|Chloroflexia	32061|Chloroflexia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS2_k127_4476202_3	857293.CAAU_0463	1.131e-76	273.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,36E3A@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS2_k127_4476202_1	926569.ANT_04080	4.437e-230	726.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi	200795|Chloroflexi	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
LZS2_k127_4478093_0	383372.Rcas_3381	3.65e-73	256.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_4478093_3	1278073.MYSTI_02049	3.504e-20	101.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_4478093_1	926569.ANT_18400	4.819e-40	160.0	COG1287@1|root,COG1287@2|Bacteria,2G785@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_449345_2	1541960.KQ78_02262	6.95e-05	46.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5,NinG
LZS2_k127_449345_1	485913.Krac_7209	2.609e-43	161.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS2_k127_449345_0	666685.R2APBS1_0144	1.087e-59	221.0	COG0477@1|root,COG2814@2|Bacteria,1PJVW@1224|Proteobacteria,1RTG0@1236|Gammaproteobacteria,1X80K@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
LZS2_k127_4513475_7	326427.Cagg_1130	1.354e-41	162.0	COG0321@1|root,COG0321@2|Bacteria,2G8KT@200795|Chloroflexi,375KR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
LZS2_k127_4513475_10	357808.RoseRS_3004	4.211e-16	88.0	2DVVU@1|root,33XEF@2|Bacteria,2GAEW@200795|Chloroflexi,375UZ@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4513475_12	926569.ANT_17240	4.881e-08	66.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1,SH3_3
LZS2_k127_4513475_4	926569.ANT_29600	1.738e-69	241.0	COG0695@1|root,COG1225@1|root,COG0695@2|Bacteria,COG1225@2|Bacteria,2G6XD@200795|Chloroflexi	200795|Chloroflexi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_4513475_11	1121378.KB899702_gene2156	1.623e-10	62.0	COG0450@1|root,COG0450@2|Bacteria,1WJFK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Redoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
LZS2_k127_4513475_5	926560.KE387023_gene2407	7.233e-57	203.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
LZS2_k127_4513475_8	926569.ANT_11840	2.031e-36	142.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_4513475_1	324602.Caur_3541	2.183e-75	277.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Arylsulfotran_2,Arylsulfotrans
LZS2_k127_4513475_2	330214.NIDE1434	9.215e-75	255.0	COG1187@1|root,COG1187@2|Bacteria,3J0RN@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.21,5.4.99.22	ko:K06178,ko:K06181,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS2_k127_4513475_0	383372.Rcas_3629	4.061e-104	352.0	COG1355@1|root,COG1355@2|Bacteria,2G835@200795|Chloroflexi	200795|Chloroflexi	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
LZS2_k127_4513475_3	709986.Deima_1286	4.674e-71	247.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_4513475_9	882082.SaccyDRAFT_1380	4.932e-28	129.0	COG2182@1|root,COG2182@2|Bacteria,2I2J8@201174|Actinobacteria,4E15M@85010|Pseudonocardiales	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_4513475_6	525904.Tter_0301	1.085e-45	186.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
LZS2_k127_4513475_13	1499967.BAYZ01000161_gene390	1.271e-05	48.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,2NNXD@2323|unclassified Bacteria	2|Bacteria	LV	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,HSDR_N,N6_Mtase,TaqI_C
LZS2_k127_4519241_0	926550.CLDAP_35470	4.541e-191	631.0	COG3103@1|root,COG3858@1|root,COG3858@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
LZS2_k127_4519241_3	383372.Rcas_1383	7.509e-67	238.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi,375AV@32061|Chloroflexia	32061|Chloroflexia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
LZS2_k127_4519241_1	1304284.L21TH_0153	1.01e-142	460.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,36DYV@31979|Clostridiaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS2_k127_4519241_2	1487953.JMKF01000048_gene2064	9.329e-99	342.0	COG0668@1|root,COG4447@1|root,COG0668@2|Bacteria,COG4447@2|Bacteria,1G0ZM@1117|Cyanobacteria,1H7Z7@1150|Oscillatoriales	1117|Cyanobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
LZS2_k127_4519241_7	533247.CRD_00341	2.521e-10	63.0	2EPAC@1|root,329XD@2|Bacteria,1GK94@1117|Cyanobacteria,1HTHE@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4519241_5	931276.Cspa_c38890	2.051e-19	99.0	COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,24HNU@186801|Clostridia	186801|Clostridia	S	SNARE-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS2_k127_4519241_6	279808.SH1203	3.776e-12	72.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4IPIZ@91061|Bacilli,4GX06@90964|Staphylococcaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS08690	GDPD
LZS2_k127_4519687_1	1121335.Clst_0632	3.489e-121	398.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3WGX1@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
LZS2_k127_4519687_0	1521187.JPIM01000114_gene1930	2.414e-156	498.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi,374WM@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS2_k127_4519687_4	926550.CLDAP_33690	5.323e-71	259.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS2_k127_4519687_5	926569.ANT_11660	2.349e-27	117.0	COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi	200795|Chloroflexi	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
LZS2_k127_4519687_2	357808.RoseRS_3583	2.206e-92	316.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,3753V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_4519687_3	395019.Bmul_6144	7.76e-73	258.0	COG2423@1|root,COG2423@2|Bacteria,1N3EI@1224|Proteobacteria,2VT4N@28216|Betaproteobacteria,1KGVW@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Ectoine utilization protein EutC	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
LZS2_k127_4521072_2	485913.Krac_2632	6.144e-95	324.0	COG0837@1|root,COG0837@2|Bacteria,2G7R9@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
LZS2_k127_4521072_0	383372.Rcas_2971	1.86e-157	509.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi,375CE@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS2_k127_4521072_4	525904.Tter_1673	1.057e-57	203.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
LZS2_k127_4521072_5	926569.ANT_12640	1.572e-44	167.0	COG1670@1|root,COG1670@2|Bacteria,2G73Y@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
LZS2_k127_4521072_1	552811.Dehly_1132	1.438e-111	370.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,34CYP@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
LZS2_k127_4521072_3	926550.CLDAP_07830	3.394e-73	269.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
LZS2_k127_4538345_5	224325.AF_1612	5.364e-16	80.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota,24607@183980|Archaeoglobi	183980|Archaeoglobi	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
LZS2_k127_4538345_7	309807.SRU_2257	9.06e-05	49.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,1FJSS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
LZS2_k127_4538345_3	596152.DesU5LDRAFT_1367	1.034e-81	284.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,42RYH@68525|delta/epsilon subdivisions,2WNT0@28221|Deltaproteobacteria,2MBQC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
LZS2_k127_4538345_6	357808.RoseRS_0410	9.195e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
LZS2_k127_4538345_2	926550.CLDAP_31350	3.393e-82	306.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_4538345_1	926550.CLDAP_39750	3.305e-82	302.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
LZS2_k127_4538345_4	460265.Mnod_4596	3.065e-22	107.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria,1JUJZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	PFAM Cyclic nucleotide-binding	MA20_39330	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS2_k127_4538345_0	926550.CLDAP_31820	3.978e-88	315.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4554635_1	383372.Rcas_1004	3.673e-163	518.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi,375TJ@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
LZS2_k127_4554635_2	1121405.dsmv_1874	3.634e-104	346.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,2MIBN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
LZS2_k127_4554635_4	357808.RoseRS_0564	2.179e-69	247.0	COG1270@1|root,COG1270@2|Bacteria,2G6JG@200795|Chloroflexi,37592@32061|Chloroflexia	32061|Chloroflexia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
LZS2_k127_4554635_0	926550.CLDAP_23850	1.517e-166	538.0	COG0079@1|root,COG1492@1|root,COG0079@2|Bacteria,COG1492@2|Bacteria,2G5PU@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
LZS2_k127_4554635_8	1407650.BAUB01000023_gene2664	0.0005102	43.0	COG3549@1|root,COG3549@2|Bacteria,1GPIN@1117|Cyanobacteria,1H3BR@1129|Synechococcus	1117|Cyanobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
LZS2_k127_4554635_3	1173264.KI913949_gene2362	2.19e-93	318.0	COG1840@1|root,COG1840@2|Bacteria,1G33G@1117|Cyanobacteria,1HE7W@1150|Oscillatoriales	1117|Cyanobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
LZS2_k127_4554635_7	391612.CY0110_15537	1.029e-05	56.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,1G1I0@1117|Cyanobacteria,3KK8R@43988|Cyanothece	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Lectin_C
LZS2_k127_4554635_5	234267.Acid_4088	2.812e-19	104.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS2_k127_4554635_6	996637.SGM_0968	3.969e-11	77.0	COG1470@1|root,COG1470@2|Bacteria,2H4ZH@201174|Actinobacteria	201174|Actinobacteria	E	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2,Ricin_B_lectin
LZS2_k127_4563839_2	402777.KB235903_gene788	8.639e-79	298.0	COG0745@1|root,COG0784@1|root,COG1511@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1511@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1GHDJ@1117|Cyanobacteria,1H8KY@1150|Oscillatoriales	1117|Cyanobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
LZS2_k127_4563839_1	1499967.BAYZ01000108_gene2206	2.097e-176	593.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
LZS2_k127_4563839_0	1499967.BAYZ01000105_gene3479	7.581e-267	900.0	COG0745@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,2NS5N@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
LZS2_k127_4563839_3	357808.RoseRS_2344	8.156e-68	266.0	COG1609@1|root,COG5002@1|root,COG1609@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,3.1.1.61	ko:K02103,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03000	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Peripla_BP_3,Response_reg,dCache_1
LZS2_k127_4575730_0	926550.CLDAP_18650	1.339e-167	541.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	2|Bacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
LZS2_k127_4575730_1	926550.CLDAP_18640	6.527e-50	180.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	2|Bacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
LZS2_k127_4580056_6	1265845.PWEIH_14901	2.439e-05	51.0	2DNID@1|root,32XP3@2|Bacteria,1UJYK@1239|Firmicutes	1239|Firmicutes	S	Cysteine-rich CPCC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPCC
LZS2_k127_4580056_0	251229.Chro_2356	1.508e-94	316.0	COG2326@1|root,COG2326@2|Bacteria,1G159@1117|Cyanobacteria,3VMQS@52604|Pleurocapsales	1117|Cyanobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
LZS2_k127_4580056_4	391625.PPSIR1_07325	1.92e-07	63.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
LZS2_k127_4580056_3	350688.Clos_1944	1.538e-22	109.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes	1239|Firmicutes	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_4580056_5	40571.JOEA01000021_gene6880	1.66e-05	49.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4E13I@85010|Pseudonocardiales	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS2_k127_4580056_2	671143.DAMO_1702	6.178e-39	156.0	COG1525@1|root,COG1525@2|Bacteria,2NQ3M@2323|unclassified Bacteria	2|Bacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Ada_Zn_binding,SNase
LZS2_k127_4580056_1	997346.HMPREF9374_3529	3.762e-61	222.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,27B3Q@186824|Thermoactinomycetaceae	91061|Bacilli	Q	Chalcone and stilbene synthases, N-terminal domain	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
LZS2_k127_4584137_1	1313421.JHBV01000015_gene5785	1.757e-147	474.0	COG0274@1|root,COG0274@2|Bacteria,4NGE3@976|Bacteroidetes	976|Bacteroidetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
LZS2_k127_4584137_0	1484460.JSWG01000015_gene1125	7.622e-241	753.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HWQG@117743|Flavobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	aldB	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_4595444_8	269800.Tfu_1289	1.342e-06	55.0	COG2186@1|root,COG2186@2|Bacteria,2ICDJ@201174|Actinobacteria,4ENZV@85012|Streptosporangiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
LZS2_k127_4595444_3	485913.Krac_5801	1.377e-72	254.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
LZS2_k127_4595444_2	1499967.BAYZ01000158_gene465	2.905e-92	312.0	COG0179@1|root,COG0179@2|Bacteria,2NP4G@2323|unclassified Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase
LZS2_k127_4595444_7	765420.OSCT_0125	1.239e-22	103.0	COG3170@1|root,COG3427@1|root,COG3170@2|Bacteria,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,376AP@32061|Chloroflexia	32061|Chloroflexia	NU	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
LZS2_k127_4595444_6	1380390.JIAT01000010_gene3336	5.134e-41	160.0	COG1878@1|root,COG1878@2|Bacteria	2|Bacteria	S	arylformamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
LZS2_k127_4595444_5	525904.Tter_2232	1.354e-43	170.0	COG1319@1|root,COG1319@2|Bacteria,2NQP8@2323|unclassified Bacteria	2|Bacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS2_k127_4595444_4	177439.DP2532	1.538e-51	187.0	COG2080@1|root,COG2080@2|Bacteria,1MWA6@1224|Proteobacteria,42RRP@68525|delta/epsilon subdivisions,2WPED@28221|Deltaproteobacteria,2MKE9@213118|Desulfobacterales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
LZS2_k127_4595444_0	1380391.JIAS01000019_gene1209	4.375e-184	586.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,2JPGD@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS2_k127_4595444_1	1380391.JIAS01000019_gene1210	1.045e-148	477.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,2JPGD@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS2_k127_4603655_3	525904.Tter_2236	1.316e-27	114.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
LZS2_k127_4603655_0	867903.ThesuDRAFT_01312	8.164e-182	585.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WCXQ@538999|Clostridiales incertae sedis	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS2_k127_4603655_1	1265502.KB905933_gene2049	6.825e-61	234.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc,HAMP
LZS2_k127_4603655_6	926550.CLDAP_26340	4.268e-18	98.0	COG1572@1|root,COG3292@1|root,COG1572@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,CARDB,Cleaved_Adhesin,DUF4465,Glyco_tran_WbsX,fn3
LZS2_k127_4603655_4	765913.ThidrDRAFT_3754	3.032e-26	119.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,1SZC1@1236|Gammaproteobacteria,1X2BA@135613|Chromatiales	135613|Chromatiales	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_4603655_2	1094980.Mpsy_0307	2.225e-37	149.0	COG2020@1|root,arCOG03580@2157|Archaea,2Y2AR@28890|Euryarchaeota,2NA7W@224756|Methanomicrobia	224756|Methanomicrobia	O	NnrU protein	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU
LZS2_k127_4603655_8	1444309.JAQG01000073_gene206	0.0002151	49.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,4HNXQ@91061|Bacilli,26ZYQ@186822|Paenibacillaceae	91061|Bacilli	S	membrane	ysdA	-	-	-	-	-	-	-	-	-	-	-	DUF1294
LZS2_k127_4603655_7	1121085.AUCI01000005_gene1054	6.48e-16	78.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1U3N3@1239|Firmicutes,4HE7D@91061|Bacilli,1ZDME@1386|Bacillus	91061|Bacilli	L	Caulimovirus viroplasmin	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
LZS2_k127_4616225_4	926550.CLDAP_07520	6.174e-28	118.0	COG0404@1|root,COG0404@2|Bacteria,2G5VA@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
LZS2_k127_4616225_2	357808.RoseRS_3026	1.091e-116	412.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
LZS2_k127_4616225_5	639030.JHVA01000001_gene1721	3.147e-20	107.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,3Y40V@57723|Acidobacteria,2JI0P@204432|Acidobacteriia	204432|Acidobacteriia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
LZS2_k127_4616225_3	357808.RoseRS_2308	8.189e-74	263.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G719@200795|Chloroflexi,377PJ@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
LZS2_k127_4616225_1	1123508.JH636446_gene6369	8.202e-126	434.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_4616225_0	118166.JH976538_gene5057	1.014e-126	418.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
LZS2_k127_4622207_2	1379698.RBG1_1C00001G1795	4.797e-09	58.0	COG0160@1|root,COG0160@2|Bacteria,2NNRV@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-III	argD	-	2.6.1.19,2.6.1.33,2.6.1.36	ko:K00823,ko:K03918,ko:K20428	ko00250,ko00410,ko00525,ko00640,ko00650,ko01100,ko01120,ko01130,map00250,map00410,map00525,map00640,map00650,map01100,map01120,map01130	M00027	R00457,R00908,R01648,R02773	RC00006,RC00062,RC00781	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_4622207_1	247490.KSU1_B0735	9.943e-156	514.0	COG0326@1|root,COG0326@2|Bacteria,2IYC7@203682|Planctomycetes	203682|Planctomycetes	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
LZS2_k127_4622207_0	340177.Cag_1780	3.103e-170	543.0	COG0205@1|root,COG0205@2|Bacteria,1FEH2@1090|Chlorobi	1090|Chlorobi	G	PFAM phosphofructokinase	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
LZS2_k127_4633613_1	926569.ANT_12170	3.076e-101	334.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
LZS2_k127_4633613_3	926550.CLDAP_10830	2.628e-75	262.0	COG0765@1|root,COG0765@2|Bacteria,2G6IJ@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
LZS2_k127_4633613_2	1128421.JAGA01000003_gene3361	5.738e-95	323.0	COG0834@1|root,COG0834@2|Bacteria,2NQ40@2323|unclassified Bacteria	2|Bacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
LZS2_k127_4633613_5	1122176.KB903619_gene5349	1.649e-07	63.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	3.2.1.17	ko:K01185,ko:K02030,ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03019,ko03029,ko03110,ko04147	1.A.33.1,3.A.1.3	-	-	LysM,SBP_bac_3
LZS2_k127_4633613_0	383372.Rcas_3343	1.071e-107	355.0	COG2084@1|root,COG2084@2|Bacteria,2G6B3@200795|Chloroflexi,376B1@32061|Chloroflexia	32061|Chloroflexia	I	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
LZS2_k127_4643640_13	314287.GB2207_01867	4.088e-08	55.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQRJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	pyridoxal-dependent decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
LZS2_k127_4643640_0	485913.Krac_5774	1.67e-119	391.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
LZS2_k127_4643640_9	1276920.ADIAG_00308	3.988e-16	81.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,1W9PZ@1268|Micrococcaceae	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
LZS2_k127_4643640_11	1158318.ATXC01000001_gene73	1.291e-09	61.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
LZS2_k127_4643640_15	1489678.RDMS_08625	1.248e-05	50.0	COG3118@1|root,COG3118@2|Bacteria,1WK8Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
LZS2_k127_4643640_5	926569.ANT_15100	5.261e-42	156.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_4643640_6	1121468.AUBR01000012_gene2571	4.278e-41	162.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,42JDW@68295|Thermoanaerobacterales	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
LZS2_k127_4643640_3	489825.LYNGBM3L_05950	2.484e-56	204.0	COG0009@1|root,COG0009@2|Bacteria	2|Bacteria	J	L-threonylcarbamoyladenylate synthase	prmC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
LZS2_k127_4643640_2	1220534.B655_0224	6.215e-59	234.0	COG0784@1|root,COG2203@1|root,COG3920@1|root,arCOG04001@1|root,arCOG06712@1|root,arCOG02335@2157|Archaea,arCOG02356@2157|Archaea,arCOG02357@2157|Archaea,arCOG04001@2157|Archaea,arCOG06537@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_4643640_7	1220534.B655_2438	4.487e-40	173.0	COG2203@1|root,arCOG02339@1|root,arCOG02339@2157|Archaea,arCOG02356@2157|Archaea	2157|Archaea	T	tigrfam pas	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_4643640_4	926550.CLDAP_08450	1.021e-49	204.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G96Q@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_9
LZS2_k127_4643640_1	926550.CLDAP_08440	1.147e-78	269.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_4643640_16	930166.CD58_13930	0.0001298	49.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	letA	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_4643640_8	1460634.JCM19037_2811	1.112e-29	122.0	COG2172@1|root,COG2172@2|Bacteria,1V6Y4@1239|Firmicutes,4HIQU@91061|Bacilli	91061|Bacilli	T	serine threonine protein kinase	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
LZS2_k127_4643640_14	290397.Adeh_0418	9.071e-06	59.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
LZS2_k127_4643640_10	864051.BurJ1DRAFT_4722	4.914e-10	62.0	COG2197@1|root,COG2197@2|Bacteria,1RH8D@1224|Proteobacteria,2WEH4@28216|Betaproteobacteria,1KPF7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_4643640_12	326427.Cagg_3668	1.672e-08	60.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,377BM@32061|Chloroflexia	32061|Chloroflexia	K	Sigma-70, region 4 type 2	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_4644600_2	765420.OSCT_2138	5.391e-111	374.0	COG4591@1|root,COG4591@2|Bacteria,2G7ZF@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS2_k127_4644600_1	765420.OSCT_2137	3.37e-141	459.0	COG4591@1|root,COG4591@2|Bacteria,2G85M@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS2_k127_4644600_3	926550.CLDAP_36970	4.3e-104	343.0	COG1136@1|root,COG1136@2|Bacteria,2G7XA@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_4644600_6	926550.CLDAP_36950	9.104e-13	69.0	COG4591@1|root,COG4591@2|Bacteria,2G85M@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS2_k127_4644600_5	313612.L8106_14770	2.031e-48	184.0	COG1235@1|root,COG1235@2|Bacteria,1G166@1117|Cyanobacteria,1H884@1150|Oscillatoriales	1117|Cyanobacteria	S	of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS2_k127_4644600_4	502025.Hoch_4229	4.54e-55	204.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2YURS@29|Myxococcales	28221|Deltaproteobacteria	T	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS2_k127_4644600_0	926550.CLDAP_09690	4.04e-146	497.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_464806_3	1121033.AUCF01000001_gene2030	1.301e-29	121.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2JRZ1@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_464806_0	383372.Rcas_3187	1.089e-146	478.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,37577@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aspartate glutamate uridylate kinase	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
LZS2_k127_464806_4	926569.ANT_06590	1.199e-20	97.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS2_k127_464806_1	321332.CYB_2315	2.25e-105	351.0	COG0031@1|root,COG0031@2|Bacteria,1GBK3@1117|Cyanobacteria,1H00H@1129|Synechococcus	1117|Cyanobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_464806_2	357808.RoseRS_0723	2.775e-79	267.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2G5TN@200795|Chloroflexi,376KE@32061|Chloroflexia	32061|Chloroflexia	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
LZS2_k127_4655589_1	1121324.CLIT_2c02290	1.642e-59	215.0	COG0318@1|root,COG0318@2|Bacteria,1UMHB@1239|Firmicutes,25GI8@186801|Clostridia	186801|Clostridia	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
LZS2_k127_4655589_0	1540221.JQNI01000002_gene1924	4.775e-160	518.0	COG2070@1|root,COG2070@2|Bacteria	2|Bacteria	S	nitronate monooxygenase activity	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
LZS2_k127_4667357_4	391612.CY0110_22007	1.519e-13	71.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,3KFNC@43988|Cyanothece	1117|Cyanobacteria	S	Leucine-rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
LZS2_k127_4667357_3	909663.KI867150_gene1223	1.043e-28	128.0	COG2770@1|root,COG2770@2|Bacteria,1NDB2@1224|Proteobacteria,42WRP@68525|delta/epsilon subdivisions,2WSBD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP
LZS2_k127_4667357_0	926550.CLDAP_23280	1.736e-84	306.0	COG1807@1|root,COG1807@2|Bacteria,2G9BJ@200795|Chloroflexi	926550.CLDAP_23280|-	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4667357_2	926550.CLDAP_15770	6.11e-59	220.0	2EPQX@1|root,33HBF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4667357_1	926550.CLDAP_15760	1.099e-81	293.0	COG1807@1|root,COG1807@2|Bacteria,2G8QS@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_4701650_2	1123401.JHYQ01000014_gene879	5.04e-17	85.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS2_k127_4701650_1	373994.Riv7116_5266	1.041e-25	120.0	COG3021@1|root,COG3021@2|Bacteria,1G9UD@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS2_k127_4701650_0	404589.Anae109_1227	6.132e-63	229.0	COG3021@1|root,COG3021@2|Bacteria,1NJVF@1224|Proteobacteria,43E6G@68525|delta/epsilon subdivisions,2WZV9@28221|Deltaproteobacteria,2Z2TR@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS2_k127_4707660_0	926550.CLDAP_12660	1.663e-127	413.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
LZS2_k127_4707660_2	511.JT27_08060	1.922e-33	140.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,2VQBX@28216|Betaproteobacteria,3T4EW@506|Alcaligenaceae	28216|Betaproteobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
LZS2_k127_4707660_1	383372.Rcas_1995	2.182e-59	210.0	COG1403@1|root,COG1403@2|Bacteria,2G6WV@200795|Chloroflexi,375TQ@32061|Chloroflexia	32061|Chloroflexia	L	SMART HNH nuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
LZS2_k127_4765957_0	926550.CLDAP_18640	8.864e-227	710.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	2|Bacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
LZS2_k127_4765957_1	28072.Nos7524_0620	3.429e-19	92.0	COG2197@1|root,COG2197@2|Bacteria,1G29J@1117|Cyanobacteria,1HK2G@1161|Nostocales	1117|Cyanobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_4765957_2	326427.Cagg_0925	8.892e-15	77.0	COG0823@1|root,COG0823@2|Bacteria,2GAJ0@200795|Chloroflexi,376FZ@32061|Chloroflexia	32061|Chloroflexia	U	PFAM WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS2_k127_4769103_13	926550.CLDAP_13470	2.464e-53	193.0	COG2087@1|root,COG2087@2|Bacteria,2G6SV@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cobalbumin biosynthesis protein	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
LZS2_k127_4769103_2	926550.CLDAP_23530	1.305e-163	520.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_4769103_14	2325.TKV_c16790	1.482e-46	173.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,42G3X@68295|Thermoanaerobacterales	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,Nitroreductase
LZS2_k127_4769103_7	649638.Trad_2632	9.206e-100	327.0	COG1225@1|root,COG1225@2|Bacteria,1WNHV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_4769103_15	717605.Theco_3575	6.536e-27	115.0	COG0346@1|root,COG0346@2|Bacteria,1V8RV@1239|Firmicutes,4HKBD@91061|Bacilli,2751J@186822|Paenibacillaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
LZS2_k127_4769103_9	697281.Mahau_2745	4.603e-76	263.0	COG2159@1|root,COG2159@2|Bacteria,1TRU0@1239|Firmicutes,248VZ@186801|Clostridia,42GGM@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM amidohydrolase 2	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS2_k127_4769103_8	1463861.JNXE01000002_gene6619	2.187e-80	280.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS2_k127_4769103_6	1489678.RDMS_10315	4.986e-118	387.0	COG0667@1|root,COG0667@2|Bacteria,1WJ87@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_4769103_5	1499967.BAYZ01000013_gene6463	5.457e-127	413.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
LZS2_k127_4769103_17	1120972.AUMH01000017_gene774	1.027e-11	66.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS2_k127_4769103_4	1120972.AUMH01000017_gene774	1.981e-133	431.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS2_k127_4769103_11	357808.RoseRS_3941	9.453e-73	250.0	COG2085@1|root,COG2085@2|Bacteria,2G900@200795|Chloroflexi,37616@32061|Chloroflexia	32061|Chloroflexia	C	NAD binding domain of 6-phosphogluconate dehydrogenase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
LZS2_k127_4769103_1	926569.ANT_24670	6.514e-167	529.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_4769103_0	926569.ANT_23500	1.485e-193	610.0	COG2768@1|root,COG2768@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21
LZS2_k127_4769103_3	1191523.MROS_0986	4.007e-153	490.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_4769103_16	488538.SAR116_1550	5.138e-20	101.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VFWP@28211|Alphaproteobacteria,4BTAJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_4769103_12	604331.AUHY01000029_gene1009	1.524e-68	240.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_4769103_10	304371.MCP_1179	5.692e-75	273.0	COG0642@1|root,COG2202@1|root,arCOG02350@1|root,arCOG02350@2157|Archaea,arCOG06192@2157|Archaea,arCOG06515@2157|Archaea	2157|Archaea	T	Contains one ATP-binding region, ATPase-like domain (IPR003594)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,PAS,PAS_3,PAS_4,PAS_9
LZS2_k127_4769970_0	316067.Geob_3673	1.601e-94	330.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,43SWS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	RHS protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat
LZS2_k127_4769970_1	338963.Pcar_1084	1.145e-15	78.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,43UIC@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
LZS2_k127_4772605_3	102129.Lepto7375DRAFT_0764	5.256e-35	138.0	COG3464@1|root,COG3464@2|Bacteria,1G9CU@1117|Cyanobacteria,1HGU0@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4772605_4	479434.Sthe_1448	3.485e-27	123.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi,27XG1@189775|Thermomicrobia	189775|Thermomicrobia	O	SurA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_3
LZS2_k127_4772605_6	1385514.N782_02325	1.65e-06	59.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4I3EY@91061|Bacilli,2YBI5@289201|Pontibacillus	91061|Bacilli	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
LZS2_k127_4772605_2	1313304.CALK_1537	8.365e-63	224.0	COG0467@1|root,COG0467@2|Bacteria	2|Bacteria	T	regulation of circadian rhythm	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
LZS2_k127_4772605_0	926550.CLDAP_21440	1.594e-70	267.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_4772605_1	1049564.TevJSym_ab00750	1.051e-67	239.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1J4E0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
LZS2_k127_4779526_5	926550.CLDAP_10940	9.878e-17	94.0	COG1807@1|root,COG4745@1|root,COG1807@2|Bacteria,COG4745@2|Bacteria,2G9MT@200795|Chloroflexi	200795|Chloroflexi	O	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4779526_0	1382306.JNIM01000001_gene3556	0.0	1402.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
LZS2_k127_4779526_2	485913.Krac_8450	5.562e-77	270.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12,N6_N4_Mtase,UPF0020
LZS2_k127_4779526_3	485913.Krac_12533	6.771e-64	221.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi	200795|Chloroflexi	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
LZS2_k127_4779526_4	485913.Krac_12532	2.011e-59	209.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
LZS2_k127_4779526_1	525904.Tter_0712	1.319e-310	964.0	COG0480@1|root,COG0480@2|Bacteria,2NNSV@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS2_k127_4786551_2	1399774.JDWH01000008_gene2038	5.849e-48	178.0	COG4225@1|root,COG4225@2|Bacteria,1NQTS@1224|Proteobacteria,1RRKB@1236|Gammaproteobacteria,3X003@547|Enterobacter	1236|Gammaproteobacteria	S	Glycosyl Hydrolase Family 88	ugl	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
LZS2_k127_4786551_1	1499967.BAYZ01000095_gene4186	2.2e-75	265.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
LZS2_k127_4786551_3	670487.Ocepr_0856	1.548e-05	57.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_4786551_0	621372.ACIH01000217_gene1073	9.859e-134	443.0	COG1653@1|root,COG1653@2|Bacteria,1TQ6X@1239|Firmicutes,4HD0Z@91061|Bacilli,274JY@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_4786551_4	1410628.JNKS01000007_gene1361	6.763e-05	47.0	COG1175@1|root,COG1175@2|Bacteria,1TRC0@1239|Firmicutes,25C59@186801|Clostridia,27U34@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_4787845_7	717785.HYPMC_1479	4.375e-24	112.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_tranf_2_4,Glycos_transf_2,RGP
LZS2_k127_4787845_3	335543.Sfum_2279	7.488e-115	401.0	COG1404@1|root,COG1404@2|Bacteria,1PFBD@1224|Proteobacteria,43A1G@68525|delta/epsilon subdivisions,2X9U2@28221|Deltaproteobacteria,2MSGE@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS2_k127_4787845_4	290315.Clim_1318	4.297e-82	284.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin,Trypsin_2
LZS2_k127_4787845_8	370438.PTH_0084	1.224e-12	72.0	COG0265@1|root,COG0265@2|Bacteria,1TRQS@1239|Firmicutes,24E3C@186801|Clostridia,260WW@186807|Peptococcaceae	186801|Clostridia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S7,Trypsin
LZS2_k127_4787845_6	926550.CLDAP_06590	2.192e-38	145.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS2_k127_4787845_0	926569.ANT_26670	4.475e-247	772.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS2_k127_4787845_11	58344.JOEL01000044_gene886	3.024e-05	47.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria	201174|Actinobacteria	I	hydrolase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
LZS2_k127_4787845_5	926550.CLDAP_31840	2.166e-71	251.0	COG0491@1|root,COG0491@2|Bacteria,2G93C@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_4787845_2	945713.IALB_1809	6.012e-131	424.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571,ko:K03497	-	-	-	-	ko00000,ko01000,ko02048,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc,RE_Eco29kI
LZS2_k127_4787845_1	316067.Geob_0005	3.861e-131	423.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,43T5S@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS2_k127_4794236_15	1347087.CBYO010000022_gene3416	1.51e-19	88.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
LZS2_k127_4794236_1	744872.Spica_2498	2.413e-234	737.0	COG2759@1|root,COG2759@2|Bacteria,2J5JZ@203691|Spirochaetes	203691|Spirochaetes	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
LZS2_k127_4794236_6	926550.CLDAP_07480	2.224e-115	384.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_4794236_16	111781.Lepto7376_0331	7.71e-14	76.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G0YJ@1117|Cyanobacteria,1H7ER@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_4794236_2	926550.CLDAP_02260	1.547e-181	584.0	COG0613@1|root,COG2865@1|root,COG0613@2|Bacteria,COG2865@2|Bacteria,2G5UU@200795|Chloroflexi	200795|Chloroflexi	K	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,PHP
LZS2_k127_4794236_8	926569.ANT_18330	4.137e-51	186.0	COG0521@1|root,COG0521@2|Bacteria,2G7HV@200795|Chloroflexi	200795|Chloroflexi	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
LZS2_k127_4794236_11	479434.Sthe_0786	1.258e-38	147.0	COG0537@1|root,COG0537@2|Bacteria,2G6VV@200795|Chloroflexi,27YE1@189775|Thermomicrobia	189775|Thermomicrobia	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
LZS2_k127_4794236_12	1158318.ATXC01000001_gene854	6.33e-37	144.0	COG1610@1|root,COG1610@2|Bacteria,2G4V2@200783|Aquificae	200783|Aquificae	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
LZS2_k127_4794236_4	926550.CLDAP_16370	1.603e-130	443.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi	200795|Chloroflexi	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
LZS2_k127_4794236_13	926550.CLDAP_16380	6.387e-26	112.0	COG0319@1|root,COG0319@2|Bacteria,2G78D@200795|Chloroflexi	200795|Chloroflexi	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
LZS2_k127_4794236_14	1042163.BRLA_c014200	1.608e-24	107.0	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,26Z2N@186822|Paenibacillaceae	91061|Bacilli	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07900	DAGK_prokar
LZS2_k127_4794236_5	272123.Anacy_0443	2.136e-121	401.0	COG1562@1|root,COG1562@2|Bacteria	2|Bacteria	I	ergosterol biosynthetic process	crtB	-	2.5.1.21,2.5.1.32,2.5.1.99	ko:K00801,ko:K02291,ko:K18163	ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,ko04714,map00100,map00906,map00909,map01062,map01100,map01110,map01130,map04714	M00097	R00702,R02065,R02872,R04218,R06223,R07270,R10177	RC00362,RC00796,RC01101,RC02839,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	SQS_PSY
LZS2_k127_4794236_19	8081.XP_008399508.1	2.085e-05	55.0	KOG3948@1|root,KOG3948@2759|Eukaryota,38CJ2@33154|Opisthokonta,3BIGQ@33208|Metazoa,3D2WG@33213|Bilateria,488HW@7711|Chordata,492FQ@7742|Vertebrata,49ZKX@7898|Actinopterygii	33208|Metazoa	A	Phosphorylated adaptor for RNA export	PHAX	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006351,GO:0006366,GO:0006403,GO:0006405,GO:0006408,GO:0006725,GO:0006807,GO:0006810,GO:0006913,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009301,GO:0009987,GO:0010467,GO:0015630,GO:0015643,GO:0015931,GO:0016070,GO:0016073,GO:0018130,GO:0019438,GO:0031974,GO:0031981,GO:0032774,GO:0033036,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0036477,GO:0042795,GO:0043025,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046907,GO:0050657,GO:0050658,GO:0051030,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0070013,GO:0071702,GO:0071704,GO:0071705,GO:0090304,GO:0097064,GO:0097159,GO:0097458,GO:0097659,GO:0098781,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K14291	ko03013,map03013	-	-	-	ko00000,ko00001	-	-	-	RNA_GG_bind
LZS2_k127_4794236_0	926550.CLDAP_05130	0.0	1036.0	COG3250@1|root,COG3250@2|Bacteria,2G5R6@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
LZS2_k127_4794236_10	644283.Micau_3318	1.193e-47	192.0	COG1175@1|root,COG1175@2|Bacteria,2IGC0@201174|Actinobacteria,4DCT9@85008|Micromonosporales	201174|Actinobacteria	G	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4794236_7	926550.CLDAP_09470	1.984e-78	275.0	2EEZR@1|root,338SU@2|Bacteria,2G8MT@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4794236_3	309801.trd_1252	2.297e-154	499.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi,27XPE@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_4794236_17	357808.RoseRS_1951	8.395e-12	74.0	COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4794236_9	926569.ANT_14880	2.201e-49	189.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_4834134_1	326427.Cagg_3255	6.13e-139	451.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi,37554@32061|Chloroflexia	32061|Chloroflexia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ChlI
LZS2_k127_4834134_0	926550.CLDAP_28120	8.683e-215	674.0	COG1760@1|root,COG1760@2|Bacteria,2G84S@200795|Chloroflexi	200795|Chloroflexi	E	Serine dehydratase beta chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
LZS2_k127_4834134_2	342949.PNA2_1140	1.893e-25	115.0	COG2379@1|root,arCOG04170@2157|Archaea,2XSTZ@28890|Euryarchaeota,242J9@183968|Thermococci	183968|Thermococci	G	Glycerate kinase	-	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
LZS2_k127_4839005_10	635013.TherJR_1595	1.956e-57	214.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,261EY@186807|Peptococcaceae	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal,dCache_1
LZS2_k127_4839005_16	264732.Moth_0741	7.849e-38	146.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,42GKD@68295|Thermoanaerobacterales	186801|Clostridia	NT	PFAM CheW domain protein	cheW1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS2_k127_4839005_3	269799.Gmet_1918	4.138e-170	557.0	COG2197@1|root,COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2197@2|Bacteria,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
LZS2_k127_4839005_6	643562.Daes_2545	1.237e-100	337.0	COG0572@1|root,COG0572@2|Bacteria,1MWCH@1224|Proteobacteria,42T0E@68525|delta/epsilon subdivisions,2WPTV@28221|Deltaproteobacteria,2M9JA@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.19,2.7.1.48	ko:K00855,ko:K00876	ko00240,ko00710,ko00983,ko01100,ko01120,ko01200,map00240,map00710,map00983,map01100,map01120,map01200	M00165,M00166	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01523,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
LZS2_k127_4839005_5	429009.Adeg_1863	2.012e-124	411.0	COG1850@1|root,COG1850@2|Bacteria,1TSZQ@1239|Firmicutes,2482N@186801|Clostridia,42G8H@68295|Thermoanaerobacterales	186801|Clostridia	G	Ribulose bisphosphate carboxylase large chain, catalytic domain	-	-	4.1.1.39,5.3.2.5	ko:K01601,ko:K08965	ko00270,ko00630,ko00710,ko01100,ko01120,ko01200,map00270,map00630,map00710,map01100,map01120,map01200	M00034,M00165,M00166,M00532	R00024,R03140,R07393	RC00172,RC00859,RC02421	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
LZS2_k127_4839005_22	1121451.DESAM_20985	1.626e-23	104.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2WKJ6@28221|Deltaproteobacteria,2M9D4@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
LZS2_k127_4839005_0	880073.Calab_1809	5.769e-208	656.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS2_k127_4839005_8	756499.Desde_0179	5.985e-67	238.0	COG0348@1|root,COG0348@2|Bacteria,1UFN6@1239|Firmicutes,25MAX@186801|Clostridia,266C5@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5
LZS2_k127_4839005_4	1129794.C427_4841	8.686e-160	517.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,46AXN@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
LZS2_k127_4839005_18	1232437.KL662010_gene1646	4.955e-35	140.0	COG1553@1|root,COG1553@2|Bacteria,1NBVC@1224|Proteobacteria,42WGH@68525|delta/epsilon subdivisions,2WRSA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
LZS2_k127_4839005_21	1121033.AUCF01000013_gene1567	1.456e-24	109.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria,2JTEB@204441|Rhodospirillales	204441|Rhodospirillales	S	Pfam:DUF461	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
LZS2_k127_4839005_9	608538.HTH_0156	2.065e-61	236.0	COG1148@1|root,COG1290@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	napF	-	-	ko:K02572,ko:K02573,ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	CCG,Cytochrome_B,FAD_binding_6,Fer2,Fer4,Fer4_4,Fer4_5,Fer4_7,FlpD,NAD_binding_1
LZS2_k127_4839005_15	1125863.JAFN01000001_gene2793	5.455e-42	169.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS2_k127_4839005_17	596151.DesfrDRAFT_0648	1.142e-35	141.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
LZS2_k127_4839005_19	671143.DAMO_0768	1.465e-34	142.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
LZS2_k127_4839005_7	1382306.JNIM01000001_gene1047	1.343e-90	304.0	COG1290@1|root,COG1290@2|Bacteria,2G8QQ@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
LZS2_k127_4839005_2	671143.DAMO_0766	3.341e-184	597.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,2NNUW@2323|unclassified Bacteria	2|Bacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	pcmB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9	ko:K03388,ko:K12527	ko00450,ko00680,ko01100,ko01120,ko01200,map00450,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R07229,R11928,R11931,R11943,R11944	RC00011,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,FlpD,Pyr_redox_2,Pyr_redox_3
LZS2_k127_4839005_23	383372.Rcas_1188	1.074e-08	62.0	COG3474@1|root,COG3474@2|Bacteria,2GA7P@200795|Chloroflexi,3760W@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
LZS2_k127_4839005_1	926550.CLDAP_28410	1.324e-207	658.0	COG0843@1|root,COG0843@2|Bacteria,2G628@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
LZS2_k127_4839005_13	1244869.H261_01542	9.496e-51	192.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,2JPAB@204441|Rhodospirillales	204441|Rhodospirillales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
LZS2_k127_4839005_11	479434.Sthe_2052	1.312e-53	194.0	COG1622@1|root,COG1622@2|Bacteria,2G8QU@200795|Chloroflexi,27YGH@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c oxidase	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
LZS2_k127_4839005_20	1120999.JONM01000015_gene2970	1.15e-27	117.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,2KRIR@206351|Neisseriales	206351|Neisseriales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
LZS2_k127_4839005_12	479434.Sthe_0241	3.581e-51	188.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,27Z5W@189775|Thermomicrobia	189775|Thermomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS2_k127_4839005_14	926550.CLDAP_28440	9.537e-47	177.0	COG1999@1|root,COG1999@2|Bacteria,2G6YC@200795|Chloroflexi	200795|Chloroflexi	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS2_k127_4841931_6	1128421.JAGA01000002_gene1478	4.686e-43	167.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	rhaS	-	-	ko:K02058,ko:K10559	ko02010,map02010	M00220,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.9	-	-	Peripla_BP_4
LZS2_k127_4841931_5	1499967.BAYZ01000103_gene3749	4.692e-44	182.0	COG1262@1|root,COG1413@1|root,COG1262@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	MA20_14850	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,HEAT_2,HEAT_PBS
LZS2_k127_4841931_2	1128421.JAGA01000002_gene1479	3.418e-121	413.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	rhaQ	-	-	ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
LZS2_k127_4841931_1	1128421.JAGA01000002_gene1480	3.981e-130	423.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
LZS2_k127_4841931_0	66874.JOFS01000022_gene5751	2.701e-173	557.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria	201174|Actinobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
LZS2_k127_4841931_4	926550.CLDAP_34840	6.616e-60	217.0	COG1349@1|root,COG1349@2|Bacteria,2G8SX@200795|Chloroflexi	200795|Chloroflexi	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
LZS2_k127_4841931_3	290315.Clim_1144	2.391e-67	233.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
LZS2_k127_4842663_0	1121405.dsmv_0043	6.795e-186	599.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MHU5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	pfam abc-1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
LZS2_k127_4842663_1	1385512.N784_15795	2.147e-53	199.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli,2YA5J@289201|Pontibacillus	91061|Bacilli	OU	Signal peptide protein	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS2_k127_4858586_2	869210.Marky_1036	1.43e-19	89.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
LZS2_k127_4858586_1	1128421.JAGA01000002_gene1307	3.188e-51	203.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8
LZS2_k127_4858586_0	1128421.JAGA01000002_gene1308	1.106e-69	243.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_4863954_8	1232410.KI421413_gene666	4.89e-09	63.0	COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,42S5S@68525|delta/epsilon subdivisions,2WNSS@28221|Deltaproteobacteria,43SHZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Lysin motif	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
LZS2_k127_4863954_5	926550.CLDAP_29380	1.133e-21	101.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	rlpA	-	3.5.1.104	ko:K03642,ko:K03791,ko:K22278	-	-	-	-	ko00000,ko01000	-	GH19	-	3D,DPBB_1,Hydrolase_2,LysM
LZS2_k127_4863954_1	926569.ANT_25840	1.697e-88	302.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
LZS2_k127_4863954_4	1330700.JQNC01000003_gene175	3.248e-28	117.0	COG0789@1|root,COG0789@2|Bacteria,1WJ4G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM MerR family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
LZS2_k127_4863954_0	383372.Rcas_0370	1.38e-106	366.0	COG0728@1|root,COG0728@2|Bacteria,2G5PF@200795|Chloroflexi,374ZA@32061|Chloroflexia	32061|Chloroflexia	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
LZS2_k127_4863954_6	926550.CLDAP_18910	4.069e-20	102.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI,Glyco_hydro_19,LysM,PG_binding_1,Peptidase_C39_2,SLT
LZS2_k127_4863954_7	316274.Haur_2160	5.12e-19	90.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
LZS2_k127_4863954_3	635013.TherJR_0654	5.918e-30	123.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia,262C8@186807|Peptococcaceae	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
LZS2_k127_4863954_2	1267535.KB906767_gene4070	4.388e-34	135.0	COG3570@1|root,COG3570@2|Bacteria	2|Bacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	strB	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
LZS2_k127_4867546_9	316274.Haur_3527	2.956e-35	139.0	COG1366@1|root,COG2202@1|root,COG3290@1|root,COG1366@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria,2GA9X@200795|Chloroflexi,376XC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	PAS_3,PAS_4,STAS
LZS2_k127_4867546_20	67315.JOBD01000026_gene1311	1.034e-12	74.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS
LZS2_k127_4867546_11	316274.Haur_2684	1.589e-31	128.0	COG2172@1|root,COG2172@2|Bacteria,2GBSX@200795|Chloroflexi,375PM@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
LZS2_k127_4867546_8	469383.Cwoe_3439	4.265e-37	147.0	COG2172@1|root,COG2172@2|Bacteria,2IKM9@201174|Actinobacteria	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
LZS2_k127_4867546_5	686340.Metal_2795	4.079e-50	185.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria,1S4BV@1236|Gammaproteobacteria,1XGXM@135618|Methylococcales	135618|Methylococcales	KT	Stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
LZS2_k127_4867546_18	264732.Moth_0907	1.713e-13	83.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,42H0N@68295|Thermoanaerobacterales	186801|Clostridia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
LZS2_k127_4867546_12	383372.Rcas_3039	5.649e-30	138.0	COG1874@1|root,COG1874@2|Bacteria,2GBMG@200795|Chloroflexi,376H5@32061|Chloroflexia	32061|Chloroflexia	G	Flagellar filament outer layer protein Flaa	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_cc
LZS2_k127_4867546_21	926569.ANT_14090	9.806e-11	75.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
LZS2_k127_4867546_1	1128421.JAGA01000002_gene1310	1.162e-150	486.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	yugH	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_4867546_3	357808.RoseRS_0881	5.902e-116	382.0	COG1209@1|root,COG1209@2|Bacteria,2GBKU@200795|Chloroflexi,3781T@32061|Chloroflexia	32061|Chloroflexia	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS2_k127_4867546_17	1173027.Mic7113_1368	1.178e-16	91.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7HR@1150|Oscillatoriales	1117|Cyanobacteria	S	WD domain, G-beta repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,SpoIIE,TIR_2,WD40
LZS2_k127_4867546_14	926550.CLDAP_01480	1.513e-26	111.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
LZS2_k127_4867546_0	324057.Pjdr2_3401	1.1e-216	694.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli,26RHB@186822|Paenibacillaceae	91061|Bacilli	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
LZS2_k127_4867546_7	644966.Tmar_0963	1.896e-45	171.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3WDTC@538999|Clostridiales incertae sedis	186801|Clostridia	U	TIGRFAM signal peptidase I, bacterial type	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
LZS2_k127_4867546_10	765420.OSCT_0260	6.312e-34	145.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi,3751W@32061|Chloroflexia	32061|Chloroflexia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS2_k127_4867546_6	926550.CLDAP_09280	1.505e-49	186.0	COG0406@1|root,COG0406@2|Bacteria,2G7D2@200795|Chloroflexi	200795|Chloroflexi	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
LZS2_k127_4867546_2	926550.CLDAP_15990	2.169e-133	437.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	metB	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
LZS2_k127_4867546_19	1122134.KB893650_gene920	7.484e-13	82.0	COG1716@1|root,COG1716@2|Bacteria,1N52Y@1224|Proteobacteria,1SCZZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
LZS2_k127_4867546_15	324602.Caur_1173	2.646e-24	120.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
LZS2_k127_4867546_13	926550.CLDAP_10530	2.159e-29	136.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_4867546_16	1337936.IJ00_06275	1.48e-17	96.0	COG4942@1|root,COG4942@2|Bacteria,1G2JU@1117|Cyanobacteria,1HJ5Y@1161|Nostocales	1117|Cyanobacteria	D	PFAM Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
LZS2_k127_4867546_4	765420.OSCT_2561	1.343e-91	321.0	COG0681@1|root,COG0681@2|Bacteria,2G85E@200795|Chloroflexi	200795|Chloroflexi	U	Family of unknown function (DUF5305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5305,Peptidase_S24
LZS2_k127_4867546_22	161528.ED21_31784	4.148e-08	62.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2K2CT@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
LZS2_k127_4867546_23	1236542.BALM01000015_gene1073	1.541e-07	64.0	COG2866@1|root,COG2866@2|Bacteria,1MZYN@1224|Proteobacteria,1RXX1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
LZS2_k127_4867604_1	1121405.dsmv_1320	2.117e-129	418.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS2_k127_4867604_4	1298860.AUEM01000008_gene2077	6.861e-08	64.0	COG1470@1|root,COG1470@2|Bacteria,2IEE6@201174|Actinobacteria,4FREC@85023|Microbacteriaceae	201174|Actinobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc
LZS2_k127_4867604_3	926560.KE387023_gene2073	4.628e-29	130.0	COG0739@1|root,COG0739@2|Bacteria,1WMXC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_4867604_0	926550.CLDAP_03580	9.94e-156	503.0	COG0477@1|root,COG2814@2|Bacteria,2GA7I@200795|Chloroflexi	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_4867604_2	765420.OSCT_0205	7.169e-121	396.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi,375I1@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_4889473_2	1379698.RBG1_1C00001G0467	2.075e-114	377.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
LZS2_k127_4889473_0	649638.Trad_0147	0.0	1259.0	COG1048@1|root,COG1048@2|Bacteria,1WIMG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acn	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
LZS2_k127_4889473_1	697281.Mahau_1302	2.377e-144	464.0	COG2189@1|root,COG2189@2|Bacteria,1UHUQ@1239|Firmicutes,25E35@186801|Clostridia,42J7H@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
LZS2_k127_4889473_3	1121289.JHVL01000027_gene221	1.017e-23	110.0	COG1226@1|root,COG1226@2|Bacteria,1UKHT@1239|Firmicutes,25FX7@186801|Clostridia,36WH0@31979|Clostridiaceae	186801|Clostridia	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
LZS2_k127_4889473_4	1177154.Y5S_03775	1.077e-13	73.0	2DNZB@1|root,32ZW6@2|Bacteria,1QMYT@1224|Proteobacteria,1TM16@1236|Gammaproteobacteria,1XQD8@135619|Oceanospirillales	135619|Oceanospirillales	S	Cysteine-rich CPCC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPCC
LZS2_k127_4913012_2	525904.Tter_1695	3.038e-49	179.0	COG0822@1|root,COG0822@2|Bacteria,2NPXN@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
LZS2_k127_4913012_3	926550.CLDAP_20390	2.838e-28	117.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
LZS2_k127_4913012_5	926569.ANT_18000	5.378e-11	67.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
LZS2_k127_4913012_1	518766.Rmar_1531	2.345e-63	221.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1FJ5K@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Thiolase, C-terminal domain	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_4913012_4	1121423.JONT01000009_gene1434	2.5e-27	124.0	COG0857@1|root,COG0857@2|Bacteria,1UFKM@1239|Firmicutes,25M79@186801|Clostridia,260XJ@186807|Peptococcaceae	186801|Clostridia	C	DRTGG domain protein	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
LZS2_k127_4913012_0	368408.Tpen_0602	6.644e-144	476.0	COG1042@1|root,arCOG01340@2157|Archaea,2XPR9@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
LZS2_k127_4927383_0	316274.Haur_3126	0.0	1030.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,376AA@32061|Chloroflexia	32061|Chloroflexia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
LZS2_k127_4927383_5	926569.ANT_01340	1.372e-117	397.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
LZS2_k127_4927383_9	1122915.AUGY01000067_gene3090	2.108e-30	124.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26Y4X@186822|Paenibacillaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
LZS2_k127_4927383_7	926550.CLDAP_17880	9.262e-82	278.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi	200795|Chloroflexi	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
LZS2_k127_4927383_10	670487.Ocepr_0856	2.497e-08	67.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_4927383_1	324602.Caur_1362	3.177e-222	704.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	ophA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_4927383_6	326427.Cagg_1750	2.963e-103	344.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_4927383_2	326427.Cagg_1751	4.737e-205	658.0	COG0444@1|root,COG4608@1|root,COG0444@2|Bacteria,COG4608@2|Bacteria,2GBKB@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS2_k127_4927383_4	324602.Caur_1365	5.305e-121	396.0	COG0601@1|root,COG0601@2|Bacteria,2G8K4@200795|Chloroflexi	200795|Chloroflexi	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_4927383_8	868595.Desca_1932	3.215e-55	203.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia,2657B@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
LZS2_k127_4927383_3	926550.CLDAP_32740	3.994e-188	593.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	bisC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS2_k127_4938982_2	118168.MC7420_1011	3.718e-22	111.0	COG0642@1|root,COG2205@2|Bacteria,1G0YJ@1117|Cyanobacteria,1H7ER@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_4938982_1	649747.HMPREF0083_06230	2.761e-54	209.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1UYB2@1239|Firmicutes,4HIMD@91061|Bacilli,26TDP@186822|Paenibacillaceae	91061|Bacilli	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
LZS2_k127_4938982_0	1121904.ARBP01000001_gene5888	3.953e-77	266.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,47S6X@768503|Cytophagia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
LZS2_k127_4941996_2	515635.Dtur_0603	4.89e-11	76.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,FlgD_ig,Peptidase_M6
LZS2_k127_4941996_4	1449976.KALB_2050	1.959e-07	64.0	COG1361@1|root,COG1361@2|Bacteria,2I8F1@201174|Actinobacteria,4E0KV@85010|Pseudonocardiales	201174|Actinobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
LZS2_k127_4941996_0	1267535.KB906767_gene1813	2.176e-54	200.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria,2JKP5@204432|Acidobacteriia	204432|Acidobacteriia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
LZS2_k127_4941996_1	111780.Sta7437_4192	1.656e-11	70.0	COG5439@1|root,COG5439@2|Bacteria,1G7UR@1117|Cyanobacteria,3VK8B@52604|Pleurocapsales	1117|Cyanobacteria	S	COGs COG5439 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4941996_3	1347086.CCBA010000012_gene2030	2.354e-08	55.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4942906_2	439235.Dalk_0895	1.759e-73	264.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg,sCache_2
LZS2_k127_4942906_0	1121405.dsmv_2296	0.0	1078.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,43C0D@68525|delta/epsilon subdivisions,2WIYN@28221|Deltaproteobacteria,2MHY4@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
LZS2_k127_4942906_3	870187.Thini_0447	2.455e-07	57.0	COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,1R7ZF@1224|Proteobacteria,1S6YQ@1236|Gammaproteobacteria,461FS@72273|Thiotrichales	1236|Gammaproteobacteria	L	PFAM Insertion element protein	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
LZS2_k127_4942906_1	324602.Caur_2655	1.24e-165	551.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2G7J8@200795|Chloroflexi,374RZ@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
LZS2_k127_4943899_8	111780.Sta7437_2823	2.607e-21	100.0	COG1357@1|root,COG1357@2|Bacteria,1G1UU@1117|Cyanobacteria,3VJH0@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_4943899_6	1047013.AQSP01000133_gene2116	3.318e-39	158.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	-	-	2.7.7.7	ko:K02342,ko:K10857,ko:K13288	ko00230,ko00240,ko01100,ko03008,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03008,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019,ko03032,ko03400	-	-	-	QSregVF_b,RNase_T
LZS2_k127_4943899_7	309801.trd_0346	1.913e-21	103.0	COG3815@1|root,COG3815@2|Bacteria,2G73B@200795|Chloroflexi,27Z7M@189775|Thermomicrobia	189775|Thermomicrobia	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
LZS2_k127_4943899_5	926569.ANT_27040	1.443e-83	282.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	ycdQ	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
LZS2_k127_4943899_10	926550.CLDAP_22180	1.111e-13	82.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_4943899_9	479434.Sthe_1215	2.06e-15	79.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi,27YPB@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
LZS2_k127_4943899_2	926550.CLDAP_25450	6.534e-103	348.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	2|Bacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
LZS2_k127_4943899_3	1382356.JQMP01000001_gene939	1.786e-89	306.0	COG1609@1|root,COG1609@2|Bacteria,2G6CQ@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_4943899_11	1408813.AYMG01000008_gene4035	0.0002477	48.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,1IQ2G@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_4943899_0	926550.CLDAP_29610	2.602e-217	683.0	COG1904@1|root,COG1904@2|Bacteria,2G7Q1@200795|Chloroflexi	200795|Chloroflexi	G	Glucuronate isomerase	-	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
LZS2_k127_4943899_1	518766.Rmar_1528	1.935e-171	550.0	2BXG3@1|root,2Z82R@2|Bacteria,4NI3Z@976|Bacteroidetes	976|Bacteroidetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
LZS2_k127_4943899_4	403833.Pmob_0444	6.766e-84	285.0	COG1028@1|root,COG1028@2|Bacteria,2GDVT@200918|Thermotogae	200918|Thermotogae	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS2_k127_4949982_0	485913.Krac_3229	1.23e-126	412.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS2_k127_4949982_1	485913.Krac_3228	1.616e-82	281.0	COG0842@1|root,COG0842@2|Bacteria,2G6H9@200795|Chloroflexi	200795|Chloroflexi	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS2_k127_4949982_2	383372.Rcas_4453	9.306e-47	175.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi,375NU@32061|Chloroflexia	32061|Chloroflexia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
LZS2_k127_4967129_2	748449.Halha_0736	1.295e-25	117.0	COG2188@1|root,COG2188@2|Bacteria,1TQQQ@1239|Firmicutes,24C86@186801|Clostridia,3WBIR@53433|Halanaerobiales	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
LZS2_k127_4967129_1	196162.Noca_1631	4.875e-139	448.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4DV65@85009|Propionibacteriales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS2_k127_4967129_0	926550.CLDAP_10970	2.771e-162	517.0	COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi	200795|Chloroflexi	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS2_k127_4967129_3	1410619.SRDD_19210	2.12e-25	106.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria,402P6@613|Serratia	1236|Gammaproteobacteria	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS2_k127_496983_2	1463825.JNXC01000040_gene5236	1.854e-12	79.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4DZJG@85010|Pseudonocardiales	201174|Actinobacteria	T	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
LZS2_k127_496983_1	479434.Sthe_1500	1.388e-111	373.0	COG0520@1|root,COG0520@2|Bacteria,2G7JU@200795|Chloroflexi,27XQN@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
LZS2_k127_496983_0	1382306.JNIM01000001_gene353	7.949e-134	436.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2G66N@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_5056723_4	518766.Rmar_2051	1.66e-05	49.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1FJ3C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
LZS2_k127_5056723_3	1380386.JIAW01000020_gene4390	2.185e-21	103.0	COG2968@1|root,COG2968@2|Bacteria,2GM1U@201174|Actinobacteria,235EY@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF541)	lpqG	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
LZS2_k127_5056723_0	1408254.T458_17235	7.452e-86	289.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26Q92@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
LZS2_k127_5056723_2	671143.DAMO_1690	5.113e-39	154.0	COG0664@1|root,COG0664@2|Bacteria,2NPVK@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS2_k127_5056723_1	357808.RoseRS_2912	2.921e-42	163.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,375R3@32061|Chloroflexia	32061|Chloroflexia	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS2_k127_5075785_7	1047013.AQSP01000062_gene1209	1.613e-68	258.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	XK27_02215	-	3.4.21.96	ko:K01361	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,PA,Peptidase_S8,SLH,YSIRK_signal,fn3_5
LZS2_k127_5075785_9	926550.CLDAP_31690	8.3e-53	196.0	COG1028@1|root,COG1028@2|Bacteria,2G8KA@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_5075785_1	314278.NB231_11184	9.217e-201	631.0	COG0517@1|root,COG0538@1|root,COG0517@2|Bacteria,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1WVYY@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
LZS2_k127_5075785_14	56110.Oscil6304_3353	8.642e-18	88.0	COG1357@1|root,COG1357@2|Bacteria,1G02C@1117|Cyanobacteria,1H8G5@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
LZS2_k127_5075785_4	926569.ANT_11650	1.38e-112	376.0	COG1239@1|root,COG1239@2|Bacteria,2G832@200795|Chloroflexi	200795|Chloroflexi	H	SMART AAA ATPase	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase
LZS2_k127_5075785_16	1121015.N789_08445	1.623e-12	79.0	COG1652@1|root,COG1652@2|Bacteria,1N3P8@1224|Proteobacteria,1SY85@1236|Gammaproteobacteria,1X82C@135614|Xanthomonadales	135614|Xanthomonadales	S	peptidoglycan-binding protein, lysm	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_5075785_17	237368.SCABRO_03959	1.942e-08	66.0	COG3023@1|root,COG3023@2|Bacteria,2J0EH@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
LZS2_k127_5075785_18	1173264.KI913951_gene4690	2.409e-08	61.0	2EJ2M@1|root,33CTU@2|Bacteria,1GGNC@1117|Cyanobacteria,1HGJ8@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5075785_13	926550.CLDAP_00660	1.313e-19	99.0	COG1319@1|root,COG1319@2|Bacteria,2G9PS@200795|Chloroflexi	200795|Chloroflexi	C	FAD binding domain in molybdopterin dehydrogenase	-	-	1.2.5.3	ko:K03519,ko:K12529	ko00450,map00450	-	R07229,R11168	RC02420,RC02800	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS2_k127_5075785_0	196162.Noca_1634	0.0	1195.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2GIVI@201174|Actinobacteria,4DND3@85009|Propionibacteriales	201174|Actinobacteria	C	Xanthine dehydrogenase, molybdenum binding subunit	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
LZS2_k127_5075785_11	309807.SRU_0997	2.706e-23	109.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria,4NEE5@976|Bacteroidetes,1FIQ3@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_5075785_3	1128421.JAGA01000001_gene2120	3.015e-118	395.0	COG0168@1|root,COG0168@2|Bacteria,2NNW1@2323|unclassified Bacteria	2|Bacteria	P	Cation transport protein	trkG	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS2_k127_5075785_5	1128421.JAGA01000001_gene2121	2.229e-72	252.0	COG0569@1|root,COG0569@2|Bacteria,2NPKV@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
LZS2_k127_5075785_19	861299.J421_3192	0.000629	51.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS2_k127_5075785_15	1265505.ATUG01000001_gene4430	6.487e-17	91.0	COG2220@1|root,COG2220@2|Bacteria,1PFZZ@1224|Proteobacteria,42SXY@68525|delta/epsilon subdivisions,2WPFM@28221|Deltaproteobacteria,2MMG4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
LZS2_k127_5075785_10	1040989.AWZU01000031_gene3906	6.272e-37	145.0	COG1051@1|root,COG1051@2|Bacteria,1R7HG@1224|Proteobacteria,2TUSV@28211|Alphaproteobacteria,3JWGB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS2_k127_5075785_6	1444309.JAQG01000033_gene2906	1.359e-68	244.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4HBHX@91061|Bacilli	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	eutB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_5075785_2	926569.ANT_25080	4.021e-140	452.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_5075785_12	1254432.SCE1572_44795	1.886e-21	109.0	COG2172@1|root,COG2197@1|root,COG2172@2|Bacteria,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	2.7.11.1	ko:K03413,ko:K04757,ko:K17752	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	HATPase_c_2,Response_reg
LZS2_k127_5075785_8	926569.ANT_23640	5.146e-56	216.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
LZS2_k127_5080205_4	649638.Trad_2668	2.149e-10	66.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_5080205_3	479434.Sthe_1693	7.522e-29	131.0	COG3693@1|root,COG5479@1|root,COG3693@2|Bacteria,COG5479@2|Bacteria,2GBGU@200795|Chloroflexi,27Y52@189775|Thermomicrobia	200795|Chloroflexi	M	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
LZS2_k127_5080205_2	309801.trd_1313	3.225e-70	261.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5080205_1	373994.Riv7116_6098	5.61e-84	302.0	COG1672@1|root,COG1672@2|Bacteria,1G0F4@1117|Cyanobacteria,1HMJD@1161|Nostocales	1117|Cyanobacteria	K	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,CHAT,TIR_2
LZS2_k127_5080205_0	215803.DB30_6069	1.751e-94	343.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YXT4@29|Myxococcales	28221|Deltaproteobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,Pkinase,WD40
LZS2_k127_5080205_5	1562701.BBOF01000078_gene150	1.205e-05	59.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,1K0Y6@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS2_k127_5090737_2	485915.Dret_1447	1.351e-55	196.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,42Q5H@68525|delta/epsilon subdivisions,2WKW4@28221|Deltaproteobacteria,2M80H@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS2_k127_5090737_1	515635.Dtur_1806	2.11e-104	347.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	gtsC	-	-	ko:K02026,ko:K17317	ko02010,map02010	M00207,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
LZS2_k127_5090737_0	665571.STHERM_c07060	1.219e-111	368.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	gtsB	-	-	ko:K02025,ko:K10118,ko:K10233,ko:K15771,ko:K17316	ko02010,map02010	M00196,M00201,M00207,M00491,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.24,3.A.1.1.28,3.A.1.1.30,3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
LZS2_k127_5090737_3	869210.Marky_2154	7.188e-10	60.0	COG1653@1|root,COG1653@2|Bacteria,1WI1U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1
LZS2_k127_5091146_2	926550.CLDAP_06470	5.663e-19	87.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
LZS2_k127_5091146_0	694427.Palpr_2664	1.668e-226	713.0	COG2060@1|root,COG2060@2|Bacteria,4NF2G@976|Bacteroidetes,2FP4S@200643|Bacteroidia,22WF2@171551|Porphyromonadaceae	976|Bacteroidetes	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
LZS2_k127_5091146_1	1303518.CCALI_01553	5.206e-58	207.0	COG2216@1|root,COG2216@2|Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAF987.Gmet_2434,iECNA114_1301.ECNA114_0634,iECSF_1327.ECSF_0632	E1-E2_ATPase,Hydrolase
LZS2_k127_511134_3	945713.IALB_2427	1.192e-72	255.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hmcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	NrfD
LZS2_k127_511134_4	429009.Adeg_0291	1.205e-66	237.0	COG0437@1|root,COG0437@2|Bacteria,1TT2G@1239|Firmicutes,24DAZ@186801|Clostridia,42GPW@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K00124,ko:K07307	ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200	-	R00519,R09501	RC02555,RC02796	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4,Fer4_11,Fer4_4,Fer4_7
LZS2_k127_511134_9	349124.Hhal_2381	1.791e-07	62.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RYPM@1236|Gammaproteobacteria,1X2QQ@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS2_k127_511134_0	926569.ANT_29430	2.262e-112	373.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS2_k127_511134_6	880073.Calab_1605	2.761e-51	196.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS2_k127_511134_10	314285.KT71_18426	1.885e-05	57.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
LZS2_k127_511134_2	926569.ANT_26970	7.093e-87	309.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
LZS2_k127_511134_1	926569.ANT_26980	5.204e-97	330.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
LZS2_k127_511134_5	926569.ANT_29450	7.81e-64	230.0	COG0583@1|root,COG0583@2|Bacteria,2G70X@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein LysR	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
LZS2_k127_511134_7	485913.Krac_11078	1.719e-40	155.0	COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi	200795|Chloroflexi	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
LZS2_k127_511134_8	1382356.JQMP01000003_gene2214	5.592e-33	128.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia	189775|Thermomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	-	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
LZS2_k127_512140_1	1286106.MPL1_09942	1.975e-05	57.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria,46132@72273|Thiotrichales	72273|Thiotrichales	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
LZS2_k127_512140_0	314230.DSM3645_13460	3.809e-20	92.0	COG1694@1|root,COG1694@2|Bacteria,2J0FY@203682|Planctomycetes	203682|Planctomycetes	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
LZS2_k127_5133224_2	765420.OSCT_0511	1.781e-43	165.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi,375RV@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
LZS2_k127_5133224_1	357808.RoseRS_0006	4.924e-72	251.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi,375HF@32061|Chloroflexia	32061|Chloroflexia	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
LZS2_k127_5133224_0	1499967.BAYZ01000060_gene6006	1.724e-116	381.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,2NPJ5@2323|unclassified Bacteria	2|Bacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
LZS2_k127_5133224_3	926569.ANT_00310	1.448e-22	112.0	COG0651@1|root,COG0651@2|Bacteria,2G9I2@200795|Chloroflexi	200795|Chloroflexi	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
LZS2_k127_5133224_4	316274.Haur_1638	1.418e-07	61.0	2F8YW@1|root,341AP@2|Bacteria,2GAD5@200795|Chloroflexi,375HY@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5136066_6	351627.Csac_2528	1.795e-06	61.0	COG3934@1|root,COG3934@2|Bacteria,1V19K@1239|Firmicutes,24DHA@186801|Clostridia	186801|Clostridia	G	hydrolase family 5	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	CBM_11,CBM_X2,Cellulase,Dockerin_1,fn3
LZS2_k127_5136066_4	1333523.L593_09910	6.261e-23	114.0	COG1520@1|root,arCOG03691@1|root,arCOG02492@2157|Archaea,arCOG03691@2157|Archaea,2Y7Q0@28890|Euryarchaeota,23SYZ@183963|Halobacteria	183963|Halobacteria	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,CarboxypepD_reg,PKD,PQQ_2,PQQ_3
LZS2_k127_5136066_3	926550.CLDAP_27370	9.208e-28	129.0	COG1520@1|root,COG1520@2|Bacteria,2G945@200795|Chloroflexi	200795|Chloroflexi	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5136066_5	926550.CLDAP_03010	1.736e-10	72.0	COG1388@1|root,COG1388@2|Bacteria,2G9RQ@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_5136066_2	1192034.CAP_3976	2.212e-46	175.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,43ADI@68525|delta/epsilon subdivisions,2X606@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
LZS2_k127_5136066_0	1340434.AXVA01000014_gene572	1.378e-160	512.0	COG0460@1|root,COG0460@2|Bacteria,1URXW@1239|Firmicutes,4HBHY@91061|Bacilli,1ZC5K@1386|Bacillus	91061|Bacilli	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Homoserine_dh,NAD_binding_3
LZS2_k127_5136066_1	926569.ANT_10920	3.184e-74	258.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
LZS2_k127_5158278_1	626887.J057_08126	2.153e-54	195.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,464VA@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048	Formyl_trans_C,Formyl_trans_N
LZS2_k127_5158278_2	926550.CLDAP_09750	2.678e-12	70.0	COG4818@1|root,COG4818@2|Bacteria,2G9PA@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
LZS2_k127_5158278_0	926569.ANT_13120	4.308e-161	526.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
LZS2_k127_5179115_0	926550.CLDAP_08140	2.069e-155	516.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
LZS2_k127_5179115_1	1541065.JRFE01000006_gene4818	1.055e-10	65.0	2E9ZW@1|root,3345B@2|Bacteria,1GR38@1117|Cyanobacteria	1117|Cyanobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
LZS2_k127_5183462_1	1304865.JAGF01000001_gene2345	4.117e-96	323.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,4F2KQ@85016|Cellulomonadaceae	201174|Actinobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.5	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
LZS2_k127_5183462_2	794903.OPIT5_19230	8.673e-92	314.0	2A1M1@1|root,30PV2@2|Bacteria,46XY9@74201|Verrucomicrobia,3K8M9@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5183462_0	525904.Tter_2055	2.229e-178	564.0	COG1063@1|root,COG1063@2|Bacteria,2NQP5@2323|unclassified Bacteria	2|Bacteria	C	Zinc-binding dehydrogenase	-	GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0030246,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_5183462_3	1229172.JQFA01000004_gene778	7.803e-28	119.0	COG2703@1|root,COG2703@2|Bacteria,1G85F@1117|Cyanobacteria,1HCGI@1150|Oscillatoriales	1117|Cyanobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
LZS2_k127_5183462_4	1499967.BAYZ01000009_gene5378	4.283e-19	88.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
LZS2_k127_5185308_0	1128421.JAGA01000002_gene1230	1.392e-127	421.0	COG0699@1|root,COG0699@2|Bacteria,2NQN2@2323|unclassified Bacteria	2|Bacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
LZS2_k127_5185308_1	867845.KI911784_gene1128	3.9e-44	171.0	COG1091@1|root,COG1091@2|Bacteria,2G9A2@200795|Chloroflexi,375MR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS2_k127_5200313_2	1128421.JAGA01000002_gene1557	2.017e-60	212.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
LZS2_k127_5200313_0	889378.Spiaf_0622	1.502e-174	553.0	COG0191@1|root,COG0191@2|Bacteria,2J5IR@203691|Spirochaetes	203691|Spirochaetes	G	aldolase class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
LZS2_k127_5200313_1	383372.Rcas_1551	7.468e-100	331.0	COG0119@1|root,COG0119@2|Bacteria,2G5KT@200795|Chloroflexi,3758Q@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
LZS2_k127_5205213_1	1128421.JAGA01000002_gene1253	1.725e-79	276.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
LZS2_k127_5205213_0	100226.SCO7523	1.934e-115	400.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_5205213_3	1121428.DESHY_50100___1	2.056e-35	145.0	COG1011@1|root,COG1011@2|Bacteria,1UIE8@1239|Firmicutes,24I5V@186801|Clostridia,262HP@186807|Peptococcaceae	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_5205213_2	195250.CM001776_gene3771	1.818e-76	263.0	COG0730@1|root,COG0730@2|Bacteria,1GPKA@1117|Cyanobacteria,1H3F4@1129|Synechococcus	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
LZS2_k127_5205213_4	926550.CLDAP_09500	7.669e-34	135.0	COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS2_k127_5217277_1	1499967.BAYZ01000118_gene3300	1.067e-145	470.0	COG1454@1|root,COG1454@2|Bacteria,2NQ5W@2323|unclassified Bacteria	2|Bacteria	C	Iron-containing alcohol dehydrogenase	CT0951	-	1.1.1.1,4.3.3.7	ko:K00001,ko:K01714,ko:K13954	ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230	M00016,M00525,M00526,M00527	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
LZS2_k127_5217277_2	1499967.BAYZ01000118_gene3301	9.395e-46	167.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	lsrG	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
LZS2_k127_5217277_3	316274.Haur_1699	7.425e-43	164.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi,377J0@32061|Chloroflexia	32061|Chloroflexia	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
LZS2_k127_5217277_5	926569.ANT_18410	6.655e-24	110.0	COG1579@1|root,COG1579@2|Bacteria,2G775@200795|Chloroflexi	200795|Chloroflexi	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
LZS2_k127_5217277_4	1297742.A176_03345	5.467e-33	140.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,42X49@68525|delta/epsilon subdivisions,2WT55@28221|Deltaproteobacteria,2YXJ2@29|Myxococcales	28221|Deltaproteobacteria	V	Ami_2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2,PG_binding_1
LZS2_k127_5217277_0	666685.R2APBS1_0795	5.169e-194	613.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,1X4KU@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_5220878_2	1128421.JAGA01000002_gene569	2.024e-98	334.0	COG1178@1|root,COG1178@2|Bacteria	2|Bacteria	P	thiamine transport	thiP	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	iAPECO1_1312.APECO1_1915,iECIAI1_1343.ECIAI1_0067,iECO103_1326.ECO103_0068,iECO111_1330.ECO111_0069,iECO26_1355.ECO26_0069,iECOK1_1307.ECOK1_0068,iECS88_1305.ECS88_0072,iECSE_1348.ECSE_0067,iECUMN_1333.ECUMN_0068,iPC815.YPO0521,iSF_1195.SF0062,iSFxv_1172.SFxv_0064,iS_1188.S0064,iUMN146_1321.UM146_23130,iUTI89_1310.UTI89_C0075	BPD_transp_1
LZS2_k127_5220878_3	351160.RCIX2172	3.307e-72	249.0	COG1611@1|root,arCOG02431@2157|Archaea,2XXME@28890|Euryarchaeota	28890|Euryarchaeota	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
LZS2_k127_5220878_1	177437.HRM2_22600	5.167e-128	420.0	COG4143@1|root,COG4143@2|Bacteria,1MUBB@1224|Proteobacteria,42PFS@68525|delta/epsilon subdivisions,2WIR3@28221|Deltaproteobacteria,2MI8U@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
LZS2_k127_5220878_4	1499967.BAYZ01000184_gene4564	1.107e-45	174.0	COG1564@1|root,COG1564@2|Bacteria,2NPUG@2323|unclassified Bacteria	2|Bacteria	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
LZS2_k127_5220878_0	316274.Haur_3267	1.139e-177	571.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
LZS2_k127_5243902_0	765177.Desmu_0636	1.11e-67	242.0	COG1131@1|root,arCOG00194@2157|Archaea,2XPS7@28889|Crenarchaeota	28889|Crenarchaeota	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS2_k127_5243902_1	1365176.N186_08580	2.894e-10	71.0	COG0842@1|root,arCOG01465@2157|Archaea	2157|Archaea	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS2_k127_5243902_2	323259.Mhun_0223	0.0002018	52.0	COG0842@1|root,arCOG01467@2157|Archaea,2XU41@28890|Euryarchaeota,2N9R3@224756|Methanomicrobia	224756|Methanomicrobia	V	TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS2_k127_5260383_4	383372.Rcas_2451	1.887e-108	355.0	COG0444@1|root,COG0444@2|Bacteria,2G893@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS2_k127_5260383_1	383372.Rcas_2450	1.186e-221	702.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,PqqD,Radical_SAM
LZS2_k127_5260383_0	383372.Rcas_2446	1.887e-303	953.0	2CC7E@1|root,2Z7WG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5260383_2	452637.Oter_4563	1.1e-161	520.0	COG0673@1|root,COG0673@2|Bacteria,46U3Z@74201|Verrucomicrobia,3K76B@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_5260383_3	649638.Trad_1840	3.685e-127	420.0	COG0823@1|root,COG0823@2|Bacteria,1WMXQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Oligogalacturonate lyase	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
LZS2_k127_526593_3	926569.ANT_22460	6.572e-64	226.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
LZS2_k127_526593_5	292459.STH3180	1.57e-55	202.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
LZS2_k127_526593_4	1123288.SOV_4c03250	3.289e-58	206.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,4H4Y5@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
LZS2_k127_526593_1	525904.Tter_1708	1.132e-90	306.0	COG1606@1|root,COG1606@2|Bacteria,2NP5T@2323|unclassified Bacteria	2|Bacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
LZS2_k127_526593_2	401526.TcarDRAFT_1531	9.168e-77	265.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,4H25Y@909932|Negativicutes	909932|Negativicutes	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
LZS2_k127_526593_0	240016.ABIZ01000001_gene502	2.705e-123	406.0	COG1641@1|root,COG1641@2|Bacteria,46THK@74201|Verrucomicrobia,2IUEA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
LZS2_k127_526593_6	1173021.ALWA01000031_gene2772	6.343e-15	76.0	COG1608@1|root,COG1608@2|Bacteria,1GBP5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM aspartate glutamate uridylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	AA_kinase
LZS2_k127_5280596_9	479434.Sthe_0380	2.056e-54	204.0	COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi,27XJZ@189775|Thermomicrobia	189775|Thermomicrobia	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
LZS2_k127_5280596_4	82654.Pse7367_1025	2.471e-95	316.0	COG0313@1|root,COG0313@2|Bacteria,1G0IF@1117|Cyanobacteria,1H7AW@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
LZS2_k127_5280596_5	926569.ANT_13700	1.941e-88	302.0	COG1609@1|root,COG1609@2|Bacteria,2G6BD@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
LZS2_k127_5280596_6	1122927.KB895415_gene4540	8.359e-84	295.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,4HA7Z@91061|Bacilli,2758U@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_5280596_7	1536774.H70357_18035	3.135e-78	276.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,4HB1J@91061|Bacilli,26U31@186822|Paenibacillaceae	91061|Bacilli	G	Lactose ABC transporter permease	-	-	-	ko:K10189	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
LZS2_k127_5280596_8	1122927.KB895415_gene4538	4.004e-66	237.0	COG0395@1|root,COG0395@2|Bacteria,1TQG0@1239|Firmicutes,4HD6Q@91061|Bacilli,26STE@186822|Paenibacillaceae	91061|Bacilli	G	Sugar ABC transporter permease	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_5280596_0	926550.CLDAP_12260	1.377e-272	854.0	COG1874@1|root,COG1874@2|Bacteria,2G604@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
LZS2_k127_5280596_2	1121377.KB906399_gene1729	8.807e-176	557.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS2_k127_5280596_3	316274.Haur_3665	7.452e-96	325.0	COG1609@1|root,COG1609@2|Bacteria,2G6DT@200795|Chloroflexi,376ZH@32061|Chloroflexia	2|Bacteria	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_5280596_1	926569.ANT_13690	5.913e-236	737.0	COG2407@1|root,COG2407@2|Bacteria,2G84V@200795|Chloroflexi	200795|Chloroflexi	G	L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
LZS2_k127_5312810_1	1173029.JH980292_gene4035	2.069e-38	147.0	COG0076@1|root,COG0076@2|Bacteria,1G3F8@1117|Cyanobacteria,1H9S6@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.15,4.1.1.86	ko:K01580,ko:K13745	ko00250,ko00260,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00260,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466,R07650	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
LZS2_k127_5312810_0	1192034.CAP_6858	2.191e-106	361.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42QDJ@68525|delta/epsilon subdivisions,2WIJ9@28221|Deltaproteobacteria,2YU69@29|Myxococcales	28221|Deltaproteobacteria	G	Alpha-amylase domain	-	-	3.2.1.10,3.2.1.20	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
LZS2_k127_5315789_0	1142394.PSMK_26780	4.5e-47	191.0	COG0589@1|root,COG1808@1|root,COG0589@2|Bacteria,COG1808@2|Bacteria,2J3I1@203682|Planctomycetes	203682|Planctomycetes	T	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
LZS2_k127_5315789_1	1449346.JQMO01000002_gene1855	3.721e-06	53.0	2EGYZ@1|root,33AR3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5326071_7	326427.Cagg_2683	1.166e-30	132.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G66G@200795|Chloroflexi,3754U@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS
LZS2_k127_5326071_4	1499967.BAYZ01000036_gene2414	7.665e-39	148.0	2BK9M@1|root,32EPT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5326071_0	1499967.BAYZ01000036_gene2415	3.556e-214	674.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
LZS2_k127_5326071_2	1120746.CCNL01000017_gene2422	8.023e-72	251.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	pgpB1	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
LZS2_k127_5326071_1	1120746.CCNL01000017_gene2423	2.125e-109	362.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
LZS2_k127_5326071_5	1128421.JAGA01000002_gene949	1.015e-32	131.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
LZS2_k127_5326071_12	316067.Geob_0432	0.0009593	44.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5326071_10	871963.Desdi_1829	3.496e-13	76.0	COG0762@1|root,COG0762@2|Bacteria,1VN1M@1239|Firmicutes,24X1E@186801|Clostridia,265M7@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
LZS2_k127_5326071_9	1123054.KB907718_gene269	4.005e-18	86.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,1WZ9P@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
LZS2_k127_5326071_6	1128421.JAGA01000002_gene1090	1.137e-30	123.0	2BZBR@1|root,32YH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
LZS2_k127_5326071_11	446470.Snas_4381	1.369e-11	66.0	2E479@1|root,32Z35@2|Bacteria,2GQXY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5326071_8	1128421.JAGA01000002_gene949	2.659e-24	108.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
LZS2_k127_5326071_3	111780.Sta7437_4112	1.666e-48	195.0	COG4932@1|root,COG4932@2|Bacteria,1GIGP@1117|Cyanobacteria,3VKF3@52604|Pleurocapsales	1117|Cyanobacteria	M	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
LZS2_k127_5326570_11	96561.Dole_1378	3.285e-50	181.0	COG0730@1|root,COG0730@2|Bacteria,1PD7F@1224|Proteobacteria,42TC8@68525|delta/epsilon subdivisions,2WPFJ@28221|Deltaproteobacteria,2MKMN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_5326570_9	880073.Calab_3265	3.776e-63	219.0	COG0432@1|root,COG0432@2|Bacteria,2NPB7@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS2_k127_5326570_1	1128421.JAGA01000003_gene3598	3.9e-139	458.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,SpoIIE
LZS2_k127_5326570_13	383372.Rcas_3831	1.382e-06	56.0	COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5326570_6	926550.CLDAP_14670	5.519e-97	345.0	COG3103@1|root,COG4991@2|Bacteria,2G8KJ@200795|Chloroflexi	200795|Chloroflexi	T	Glycosyltransferase WbsX	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_99
LZS2_k127_5326570_10	1120972.AUMH01000001_gene1051	2.548e-57	205.0	COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,279T1@186823|Alicyclobacillaceae	91061|Bacilli	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
LZS2_k127_5326570_7	926549.KI421517_gene1458	2.897e-78	272.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47PEN@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS2_k127_5326570_2	756272.Plabr_0071	4.695e-135	442.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
LZS2_k127_5326570_3	1331060.RLDS_25525	5.531e-124	414.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2TUW3@28211|Alphaproteobacteria,2K25Z@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
LZS2_k127_5326570_4	395493.BegalDRAFT_2144	2.962e-119	392.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria,1QWW7@1224|Proteobacteria,1T4BI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_5326570_8	357808.RoseRS_2347	9.467e-67	234.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HD,HD_5,HisKA,Response_reg
LZS2_k127_5326570_0	118168.MC7420_5151	1.146e-162	565.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1H9EM@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	GAF,GAF_2,HATPase_c,HisKA,MASE1,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_5326570_12	1379698.RBG1_1C00001G0287	1.285e-27	132.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
LZS2_k127_5326570_5	402777.KB235903_gene774	5.781e-109	374.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
LZS2_k127_534350_3	1173025.GEI7407_1920	3.402e-137	445.0	COG0409@1|root,COG0409@2|Bacteria,1G0NJ@1117|Cyanobacteria,1H8DU@1150|Oscillatoriales	1117|Cyanobacteria	O	hydrogenase expression formation protein	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
LZS2_k127_534350_7	35754.JNYJ01000042_gene1380	1.211e-21	96.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria,4DKQG@85008|Micromonosporales	201174|Actinobacteria	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
LZS2_k127_534350_1	926569.ANT_17860	1.612e-209	678.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
LZS2_k127_534350_2	926550.CLDAP_26850	4.331e-152	496.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5	ko:K00848,ko:K00851,ko:K00854,ko:K00862	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
LZS2_k127_534350_4	926550.CLDAP_07480	2.563e-128	422.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_534350_8	1150474.JQJI01000006_gene839	6.5e-12	78.0	COG1388@1|root,COG4733@1|root,COG1388@2|Bacteria,COG4733@2|Bacteria,2GE91@200918|Thermotogae	2|Bacteria	M	Fibronectin type III domain	-	-	-	ko:K03933	-	-	-	-	ko00000	-	AA10,CBM73	-	Bac_DNA_binding,CHAP,fn3
LZS2_k127_534350_0	926550.CLDAP_31240	2.008e-215	678.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS2_k127_534350_6	285514.JNWO01000003_gene7078	3.614e-41	166.0	COG1397@1|root,COG1397@2|Bacteria	2|Bacteria	O	ADP-ribosylglycohydrolase	yegU	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
LZS2_k127_534350_5	460265.Mnod_1045	1.327e-92	311.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2TUKT@28211|Alphaproteobacteria,1JTP6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
LZS2_k127_5345891_2	1157640.AQWO01000002_gene4567	1.024e-33	134.0	COG0500@1|root,COG1051@1|root,COG0500@2|Bacteria,COG1051@2|Bacteria,2GKYW@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4,Methyltransf_11,NUDIX
LZS2_k127_5345891_1	485916.Dtox_2038	8.463e-59	207.0	COG0346@1|root,COG0346@2|Bacteria,1V6FU@1239|Firmicutes,24U9K@186801|Clostridia,265KW@186807|Peptococcaceae	186801|Clostridia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
LZS2_k127_5345891_0	344747.PM8797T_29967	5.696e-78	269.0	COG4335@1|root,COG4335@2|Bacteria,2IZG7@203682|Planctomycetes	203682|Planctomycetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
LZS2_k127_5346064_0	1173020.Cha6605_4047	2.287e-24	117.0	COG3385@1|root,COG5659@1|root,COG3385@2|Bacteria,COG5659@2|Bacteria,1G1TK@1117|Cyanobacteria	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
LZS2_k127_5352921_9	502025.Hoch_6548	2.092e-26	109.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,43CYW@68525|delta/epsilon subdivisions,2X872@28221|Deltaproteobacteria,2Z18H@29|Myxococcales	1224|Proteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS_4,Response_reg,SpoIIE
LZS2_k127_5352921_10	1173028.ANKO01000080_gene4665	1.047e-14	86.0	COG0758@1|root,COG0758@2|Bacteria,1G3JW@1117|Cyanobacteria,1H863@1150|Oscillatoriales	1117|Cyanobacteria	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	-	-	-	-	-	-	-	-	-	-	-	-	DNA_processg_A
LZS2_k127_5352921_1	1444309.JAQG01000100_gene4749	2.83e-125	414.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4HAIC@91061|Bacilli,26RUX@186822|Paenibacillaceae	91061|Bacilli	P	Arsenical pump membrane protein	-	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB,CitMHS
LZS2_k127_5352921_11	316274.Haur_3438	1.328e-12	78.0	COG0347@1|root,COG0347@2|Bacteria,2G9NA@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5352921_8	926550.CLDAP_29590	1.59e-30	130.0	28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5352921_2	243164.DET1215	7.238e-76	264.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi,34D04@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS2_k127_5352921_3	926569.ANT_17680	3.904e-75	263.0	COG2047@1|root,COG2047@2|Bacteria	2|Bacteria	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
LZS2_k127_5352921_4	926550.CLDAP_03010	1.071e-50	192.0	COG1388@1|root,COG1388@2|Bacteria,2G9RQ@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_5352921_7	1122138.AQUZ01000027_gene879	6.096e-34	136.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
LZS2_k127_5352921_5	1173025.GEI7407_2503	1.197e-44	187.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS_3,PAS_9
LZS2_k127_5352921_0	765420.OSCT_1702	1.745e-135	466.0	COG0642@1|root,COG2205@2|Bacteria,2G81I@200795|Chloroflexi,3780A@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
LZS2_k127_5352921_6	489825.LYNGBM3L_22900	1.437e-38	150.0	COG0642@1|root,COG2205@2|Bacteria,1G0YJ@1117|Cyanobacteria,1H7ER@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_5359578_6	768704.Desmer_3711	2.171e-10	64.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,26181@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_8
LZS2_k127_5359578_3	1121468.AUBR01000005_gene97	8.857e-74	265.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,42FW0@68295|Thermoanaerobacterales	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_5359578_1	1403819.BATR01000093_gene2905	5.016e-114	378.0	COG3239@1|root,COG3239@2|Bacteria,46SX7@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Fatty acid desaturase	desA	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS2_k127_5359578_7	1123401.JHYQ01000014_gene879	0.000186	48.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,1RZ45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS2_k127_5359578_0	857087.Metme_3931	1.002e-177	584.0	COG0577@1|root,COG0577@2|Bacteria,1PJZX@1224|Proteobacteria,1RU56@1236|Gammaproteobacteria,1XDTW@135618|Methylococcales	135618|Methylococcales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_5359578_5	479434.Sthe_3331	1.383e-43	163.0	2BVHN@1|root,32SWN@2|Bacteria,2G8ZV@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
LZS2_k127_5359578_4	765420.OSCT_2689	3.361e-50	191.0	COG4632@1|root,COG4632@2|Bacteria,2G8RE@200795|Chloroflexi,375J8@32061|Chloroflexia	32061|Chloroflexia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
LZS2_k127_5359578_2	1499967.BAYZ01000182_gene4446	4.759e-80	272.0	COG1816@1|root,COG1816@2|Bacteria,2NR0J@2323|unclassified Bacteria	2|Bacteria	F	Adenosine/AMP deaminase	add	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.2,3.5.4.4,3.5.4.40	ko:K01488,ko:K18286,ko:K21053	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01244,R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
LZS2_k127_5398939_8	1430440.MGMSRv2_0461	1.553e-45	169.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,2JTRD@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
LZS2_k127_5398939_6	246194.CHY_2383	1.906e-90	307.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,42FAT@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
LZS2_k127_5398939_7	926550.CLDAP_37130	1.34e-71	259.0	COG2197@1|root,COG3055@1|root,COG2197@2|Bacteria,COG3055@2|Bacteria,2G6NU@200795|Chloroflexi	200795|Chloroflexi	KT	Kelch repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Kelch_1,Kelch_4
LZS2_k127_5398939_1	926550.CLDAP_37840	1.009e-166	535.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
LZS2_k127_5398939_11	926569.ANT_16040	1.484e-31	132.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
LZS2_k127_5398939_12	335541.Swol_1496	2.196e-22	99.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,42K68@68298|Syntrophomonadaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
LZS2_k127_5398939_10	479434.Sthe_1868	4.565e-38	149.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi,27YEY@189775|Thermomicrobia	189775|Thermomicrobia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
LZS2_k127_5398939_2	1128421.JAGA01000003_gene3142	1.128e-119	395.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	5.99.1.2	ko:K03168,ko:K04096	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_processg_A
LZS2_k127_5398939_3	1128421.JAGA01000004_gene2627	2.789e-117	387.0	COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria	2|Bacteria	M	Mannose-6-phosphate isomerase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
LZS2_k127_5398939_0	926569.ANT_15990	1.414e-302	947.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
LZS2_k127_5398939_4	215803.DB30_4934	9.855e-108	365.0	COG0464@1|root,COG0464@2|Bacteria,1MXFG@1224|Proteobacteria,42PBF@68525|delta/epsilon subdivisions,2WJG0@28221|Deltaproteobacteria,2YZK1@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
LZS2_k127_5398939_13	1117379.BABA_24455	3.124e-15	86.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli,1ZCAD@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS2_k127_5398939_14	765911.Thivi_3623	0.0008743	51.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,1RYY4@1236|Gammaproteobacteria,1WXJW@135613|Chromatiales	135613|Chromatiales	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
LZS2_k127_5398939_5	926550.CLDAP_27990	1.918e-100	340.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_5398939_9	326427.Cagg_0017	1.586e-39	148.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
LZS2_k127_543475_5	701176.VIBRN418_14431	4.082e-10	66.0	COG1266@1|root,COG1266@2|Bacteria,1P0IE@1224|Proteobacteria,1RS9M@1236|Gammaproteobacteria,1XV8N@135623|Vibrionales	135623|Vibrionales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS2_k127_543475_0	383372.Rcas_3322	2.264e-68	239.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
LZS2_k127_543475_4	326424.FRAAL5505	5.024e-21	99.0	COG0452@1|root,COG0452@2|Bacteria,2GP82@201174|Actinobacteria	201174|Actinobacteria	H	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavoprotein
LZS2_k127_543475_2	525904.Tter_1845	1.044e-57	213.0	COG0451@1|root,COG0451@2|Bacteria,2NR1N@2323|unclassified Bacteria	2|Bacteria	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS2_k127_543475_1	926549.KI421517_gene1986	3.992e-63	225.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,47KPR@768503|Cytophagia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
LZS2_k127_543475_3	926550.CLDAP_04460	1.179e-41	167.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5454771_0	1304880.JAGB01000002_gene1805	3.423e-104	347.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,24AVR@186801|Clostridia	186801|Clostridia	EQ	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
LZS2_k127_5454771_1	1274374.CBLK010000053_gene2271	1.665e-41	171.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,26TP2@186822|Paenibacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5454771_2	1125863.JAFN01000001_gene2873	2.317e-29	127.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q9F@68525|delta/epsilon subdivisions,2WMM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS2_k127_5456469_4	525904.Tter_1682	6.389e-48	186.0	COG0631@1|root,COG0631@2|Bacteria,2NR1Q@2323|unclassified Bacteria	2|Bacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS2_k127_5456469_3	517418.Ctha_1990	1.322e-91	319.0	COG1169@1|root,COG1169@2|Bacteria,1FDKT@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the conversion of chorismate to isochorismate	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
LZS2_k127_5456469_0	696747.NIES39_C02430	8.51e-165	537.0	COG1165@1|root,COG1165@2|Bacteria,1G1FW@1117|Cyanobacteria,1H8TT@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
LZS2_k127_5456469_1	340177.Cag_1719	2.115e-135	435.0	COG0447@1|root,COG0447@2|Bacteria,1FDH0@1090|Chlorobi	1090|Chlorobi	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS2_k127_5456469_2	517418.Ctha_1985	1.106e-95	326.0	COG0318@1|root,COG0318@2|Bacteria,1FDIV@1090|Chlorobi	1090|Chlorobi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
LZS2_k127_545910_2	1379698.RBG1_1C00001G1060	3.344e-75	263.0	COG1009@1|root,COG1009@2|Bacteria,2NNU6@2323|unclassified Bacteria	2|Bacteria	CP	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
LZS2_k127_545910_0	247490.KSU1_D0316	4.243e-158	512.0	COG1008@1|root,COG1008@2|Bacteria,2IX79@203682|Planctomycetes	203682|Planctomycetes	C	proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
LZS2_k127_545910_1	316067.Geob_0475	1.295e-140	462.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS2_k127_545910_3	1122917.KB899659_gene5088	3.6e-25	110.0	COG0745@1|root,COG0745@2|Bacteria,1UD16@1239|Firmicutes,4HX3U@91061|Bacilli,26ZCD@186822|Paenibacillaceae	91061|Bacilli	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_5463283_1	1499967.BAYZ01000103_gene3724	2.01e-97	343.0	COG3275@1|root,COG3920@1|root,COG3275@2|Bacteria,COG3920@2|Bacteria,2NPS5@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.7.13.3,2.7.7.65	ko:K00936,ko:K16923,ko:K18967	-	M00582,M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.28,9.B.34.1.1	-	-	5TM-5TMR_LYT,ECF_trnsprt,GGDEF,HATPase_c,H_kinase_N,HisKA_2
LZS2_k127_5463283_2	330214.NIDE1123	1.77e-23	104.0	COG0745@1|root,COG0745@2|Bacteria	330214.NIDE1123|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5463283_3	264732.Moth_0968	6.836e-20	92.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,42H76@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
LZS2_k127_5463283_0	383372.Rcas_1300	8.451e-198	634.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
LZS2_k127_5480563_5	867845.KI911784_gene3664	1.405e-28	126.0	COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,3764Y@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
LZS2_k127_5480563_3	1237149.C900_05711	7.165e-87	296.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_5480563_4	886293.Sinac_2076	6.824e-29	121.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
LZS2_k127_5480563_1	1499967.BAYZ01000186_gene3977	9.95e-205	644.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Fer4_7,Pyr_redox_2
LZS2_k127_5480563_2	1128421.JAGA01000003_gene3330	2.099e-123	404.0	COG4974@1|root,COG4974@2|Bacteria,2NRIN@2323|unclassified Bacteria	2|Bacteria	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS2_k127_5480563_0	1499967.BAYZ01000095_gene4145	0.0	1198.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,2NNW8@2323|unclassified Bacteria	2|Bacteria	L	DNA helicase	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
LZS2_k127_5502783_2	926550.CLDAP_10770	1.942e-10	68.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Trypsin,VCBS
LZS2_k127_5502783_1	1121430.JMLG01000003_gene597	3.115e-47	184.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS2_k127_5502783_0	1131462.DCF50_p2804	1.22e-71	248.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_5508629_6	521674.Plim_0932	6.067e-29	128.0	COG1262@1|root,COG1262@2|Bacteria,2IXQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FGE-sulfatase,TPR_11
LZS2_k127_5508629_0	479434.Sthe_2394	1.05e-102	347.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi,27XYQ@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
LZS2_k127_5508629_3	247490.KSU1_D0536	3.888e-58	207.0	COG3772@1|root,COG3772@2|Bacteria	2|Bacteria	S	cytolysis by virus of host cell	-	-	3.2.1.17	ko:K01185,ko:K03791	-	-	-	-	ko00000,ko01000	-	GH19	-	DUF4231,Glyco_hydro_19,Peptidase_M15_3,Phage_lysozyme
LZS2_k127_5508629_7	1162668.LFE_2334	4.459e-12	72.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5508629_2	240015.ACP_0794	9.762e-77	264.0	COG1573@1|root,COG1573@2|Bacteria,3Y4AT@57723|Acidobacteria,2JJ4U@204432|Acidobacteriia	204432|Acidobacteriia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS2_k127_5508629_8	1122614.JHZF01000011_gene1390	7.181e-05	52.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,2PD8U@252301|Oceanicola	28211|Alphaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L21p
LZS2_k127_5508629_5	312309.VF_1342	1.199e-36	141.0	COG1917@1|root,COG1917@2|Bacteria,1MZNT@1224|Proteobacteria,1S8TU@1236|Gammaproteobacteria,1XYMY@135623|Vibrionales	135623|Vibrionales	S	Cupin domain	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
LZS2_k127_5508629_1	869210.Marky_0228	6.578e-84	293.0	COG0457@1|root,COG3271@1|root,COG0457@2|Bacteria,COG3271@2|Bacteria,1WKXF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_2,TPR_8
LZS2_k127_5508629_4	635013.TherJR_2276	8.794e-54	194.0	COG0755@1|root,COG0755@2|Bacteria,1V4A6@1239|Firmicutes,24IWH@186801|Clostridia,264K0@186807|Peptococcaceae	186801|Clostridia	O	Cytochrome c assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
LZS2_k127_5532664_5	756067.MicvaDRAFT_3366	2.207e-93	314.0	COG1718@1|root,COG1718@2|Bacteria,1G3HN@1117|Cyanobacteria,1H954@1150|Oscillatoriales	1117|Cyanobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5532664_7	1242864.D187_009501	5.133e-42	157.0	2CP0Z@1|root,32SI8@2|Bacteria,1RK5X@1224|Proteobacteria,434SF@68525|delta/epsilon subdivisions,2X904@28221|Deltaproteobacteria,2Z0HI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
LZS2_k127_5532664_4	926550.CLDAP_25110	3.373e-97	331.0	COG2807@1|root,COG2807@2|Bacteria,2GBI4@200795|Chloroflexi	200795|Chloroflexi	P	Nucleoside H+ symporter	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
LZS2_k127_5532664_6	1206101.AZXC01000006_gene3888	7.5e-66	238.0	COG2113@1|root,COG2113@2|Bacteria,2GP39@201174|Actinobacteria	201174|Actinobacteria	E	glycine betaine transport	proX	-	-	ko:K02002	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
LZS2_k127_5532664_1	439493.PB7211_211	7.411e-136	458.0	COG4176@1|root,COG4176@2|Bacteria,1MUM4@1224|Proteobacteria,2TT2M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type proline glycine betaine transport system permease component	-	-	-	ko:K02001	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
LZS2_k127_5532664_2	869210.Marky_0058	1.012e-124	411.0	COG3620@1|root,COG4175@1|root,COG3620@2|Bacteria,COG4175@2|Bacteria,1WJRS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG4175 ABC-type proline glycine betaine transport system, ATPase component	-	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
LZS2_k127_5532664_0	1121451.DESAM_21610	1.707e-160	521.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,2MAG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
LZS2_k127_5532664_8	913865.DOT_5104	3.581e-40	154.0	COG0454@1|root,COG0454@2|Bacteria,1UID4@1239|Firmicutes,25EI4@186801|Clostridia,2660X@186807|Peptococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
LZS2_k127_5532664_3	869213.JCM21142_41818	3.846e-112	376.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,47JZA@768503|Cytophagia	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acd	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_dehyd_C
LZS2_k127_5547214_0	1382306.JNIM01000001_gene957	1.701e-91	310.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_5547214_2	926550.CLDAP_17520	3.085e-16	94.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_5547214_1	1173023.KE650771_gene2474	1.247e-53	215.0	COG1807@1|root,COG1807@2|Bacteria,1G4QV@1117|Cyanobacteria	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_5555324_0	926569.ANT_11560	3.906e-95	330.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_5555324_3	91464.S7335_3534	8.778e-07	63.0	COG3307@1|root,COG3307@2|Bacteria,1G277@1117|Cyanobacteria,1H0B8@1129|Synechococcus	1117|Cyanobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS2_k127_5555324_2	926569.ANT_11570	2.065e-10	65.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
LZS2_k127_5572046_2	926550.CLDAP_37380	2.043e-21	95.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS2_k127_5572046_0	1121382.JQKG01000024_gene1550	1.202e-79	275.0	COG5322@1|root,COG5322@2|Bacteria,1WI86@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5572046_1	869210.Marky_2009	2.447e-68	249.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1WJ1A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
LZS2_k127_5598464_3	745776.DGo_CA2685	8.879e-19	93.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_5598464_0	485913.Krac_11745	1.31e-109	367.0	COG0438@1|root,COG0438@2|Bacteria,2G5QJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_5598464_1	485913.Krac_11744	4.068e-85	295.0	COG0438@1|root,COG0438@2|Bacteria,2G7W6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_5598464_2	644282.Deba_1438	4.662e-75	257.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS2_k127_5607503_3	886293.Sinac_7174	5.209e-37	146.0	COG2716@1|root,COG2716@2|Bacteria	2|Bacteria	E	regulation of RNA biosynthetic process	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
LZS2_k127_5607503_4	926569.ANT_16430	4.809e-29	122.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5607503_0	1125863.JAFN01000001_gene322	2.587e-95	321.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS2_k127_5607503_5	867845.KI911784_gene1248	2.396e-28	126.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi,375R5@32061|Chloroflexia	32061|Chloroflexia	S	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
LZS2_k127_5607503_1	1000565.METUNv1_00578	1.405e-56	204.0	COG3404@1|root,COG3404@2|Bacteria,1R781@1224|Proteobacteria,2VUV6@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C,HutD
LZS2_k127_5607503_2	584708.Apau_0124	1.408e-52	190.0	COG3643@1|root,COG3643@2|Bacteria,3TA3X@508458|Synergistetes	508458|Synergistetes	E	Formiminotransferase domain, N-terminal subdomain	-	-	-	-	-	-	-	-	-	-	-	-	FTCD,FTCD_N
LZS2_k127_5608658_1	671143.DAMO_2651	1.555e-131	426.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
LZS2_k127_5608658_3	28532.XP_010546600.1	1.619e-63	225.0	COG0120@1|root,KOG3075@2759|Eukaryota,37IAG@33090|Viridiplantae,3G8FU@35493|Streptophyta,3HNB3@3699|Brassicales	35493|Streptophyta	G	ribose-5-phosphate isomerase 3, chloroplastic	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009725,GO:0009735,GO:0009941,GO:0009987,GO:0010033,GO:0015977,GO:0015979,GO:0016020,GO:0016051,GO:0019253,GO:0019685,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042221,GO:0042651,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051704,GO:0051707,GO:0055035,GO:0071704,GO:0098542,GO:1901576	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
LZS2_k127_5608658_2	326427.Cagg_1560	2.453e-114	381.0	COG0303@1|root,COG0303@2|Bacteria,2G6AK@200795|Chloroflexi,375EW@32061|Chloroflexia	32061|Chloroflexia	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS2_k127_5608658_0	1173027.Mic7113_4717	2.174e-133	431.0	COG1397@1|root,COG1397@2|Bacteria,1G437@1117|Cyanobacteria,1H9KV@1150|Oscillatoriales	1117|Cyanobacteria	O	ADP-ribosylglycohydrolase	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
LZS2_k127_5608658_4	767434.Fraau_2000	6.194e-15	77.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,1S1WW@1236|Gammaproteobacteria,1XD2G@135614|Xanthomonadales	135614|Xanthomonadales	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
LZS2_k127_5622271_1	525904.Tter_2128	2.542e-54	204.0	COG1477@1|root,COG1477@2|Bacteria,2NPJE@2323|unclassified Bacteria	2|Bacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
LZS2_k127_5622271_0	1183438.GKIL_1905	1.194e-80	278.0	COG5002@1|root,COG5002@2|Bacteria,1GPX6@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_562296_1	926550.CLDAP_32750	5.879e-42	157.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS2_k127_562296_0	926569.ANT_20960	3.687e-81	280.0	COG0803@1|root,COG0803@2|Bacteria,2G6XK@200795|Chloroflexi	200795|Chloroflexi	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09818	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
LZS2_k127_5627796_1	509191.AEDB02000022_gene2925	2.592e-78	282.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,3WIT1@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,Peptidase_S8,SLH
LZS2_k127_5627796_0	926569.ANT_11480	2.466e-103	349.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_5627796_3	926569.ANT_29030	8.18e-21	94.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi	200795|Chloroflexi	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
LZS2_k127_5627796_2	204669.Acid345_1802	5.925e-43	162.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,3Y85P@57723|Acidobacteria	57723|Acidobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,Guanylate_cyc
LZS2_k127_5637962_1	1122611.KB903996_gene7599	1.63e-63	244.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GN4X@201174|Actinobacteria,4EI2W@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_5637962_2	1280689.AUJC01000004_gene482	4.036e-59	214.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,36DTD@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_5637962_3	1033734.CAET01000038_gene67	3.906e-08	64.0	COG0454@1|root,COG0456@2|Bacteria,1UZC5@1239|Firmicutes,4HFDR@91061|Bacilli,1ZE2E@1386|Bacillus	91061|Bacilli	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6
LZS2_k127_5642093_1	926569.ANT_16800	1.024e-72	250.0	COG1003@1|root,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
LZS2_k127_5642093_0	926569.ANT_16790	1.036e-156	506.0	COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS2_k127_5642093_2	670487.Ocepr_1642	8.88e-46	169.0	COG0509@1|root,COG0509@2|Bacteria,1WJYK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
LZS2_k127_5649217_0	1128421.JAGA01000002_gene144	1.263e-250	800.0	COG3383@1|root,COG3383@2|Bacteria,2NNQ6@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	nuoG	-	1.17.1.9,1.6.5.3	ko:K00123,ko:K00336	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
LZS2_k127_5649217_1	1379698.RBG1_1C00001G1055	2.032e-147	478.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
LZS2_k127_5655754_1	926550.CLDAP_29840	2.069e-25	113.0	COG3023@1|root,COG4423@1|root,COG3023@2|Bacteria,COG4423@2|Bacteria	2|Bacteria	S	positive regulation of growth	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	Amidase_2,PG_binding_1,PSK_trans_fac
LZS2_k127_5655754_0	316274.Haur_3336	3.507e-46	181.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
LZS2_k127_5655754_2	1233950.IW22_04520	5.009e-17	87.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I2T3@117743|Flavobacteriia,3ZS40@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
LZS2_k127_5656295_6	1298920.KI911353_gene3098	8.242e-55	199.0	COG1312@1|root,COG1312@2|Bacteria,1V03M@1239|Firmicutes,247U9@186801|Clostridia,222KZ@1506553|Lachnoclostridium	186801|Clostridia	G	D-mannonate dehydratase (UxuA)	-	-	-	-	-	-	-	-	-	-	-	-	UxuA
LZS2_k127_5656295_5	665571.STHERM_c04250	6.11e-102	342.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_5656295_0	1499967.BAYZ01000184_gene4600	8.438e-171	541.0	COG4608@1|root,COG4608@2|Bacteria,2NQH4@2323|unclassified Bacteria	2|Bacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	gsiA_8	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS2_k127_5656295_3	1499967.BAYZ01000184_gene4599	1.89e-135	438.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS2_k127_5656295_2	1499967.BAYZ01000184_gene4598	6.623e-149	481.0	COG1173@1|root,COG1173@2|Bacteria,2NQF6@2323|unclassified Bacteria	2|Bacteria	U	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_5656295_4	1499967.BAYZ01000184_gene4597	1.268e-121	398.0	COG0601@1|root,COG0601@2|Bacteria,2NQBI@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	oppB	-	2.4.2.7	ko:K00759,ko:K02033	ko00230,ko01100,ko02024,map00230,map01100,map02024	M00239	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko00002,ko01000,ko02000,ko04147	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_5656295_1	1499967.BAYZ01000184_gene4596	7.26e-164	526.0	COG0747@1|root,COG0747@2|Bacteria,2NQSA@2323|unclassified Bacteria	2|Bacteria	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_5671236_1	397278.JOJN01000004_gene1411	2.28e-05	55.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4DN0Q@85009|Propionibacteriales	201174|Actinobacteria	O	prohibitin homologues	hflK	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_5671236_0	1449063.JMLS01000005_gene3101	1.051e-21	96.0	COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes	1239|Firmicutes	T	hydrolase (HAD superfamily)	-	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS2_k127_5674836_4	926560.KE387027_gene1040	1.348e-22	109.0	COG0683@1|root,COG0683@2|Bacteria,1WI02@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS2_k127_5674836_0	357808.RoseRS_1065	1.056e-106	358.0	COG0297@1|root,COG0297@2|Bacteria,2G7ZU@200795|Chloroflexi,375BU@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_5674836_1	357808.RoseRS_4052	1.149e-106	355.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,3759I@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS2_k127_5674836_3	383372.Rcas_3361	3.988e-68	239.0	COG0548@1|root,COG0548@2|Bacteria,2G6ZG@200795|Chloroflexi,375PI@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
LZS2_k127_5674836_2	926550.CLDAP_16930	8.843e-94	314.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_5679624_1	649639.Bcell_1278	2.055e-97	327.0	COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,1ZBDC@1386|Bacillus	91061|Bacilli	E	Acetylornithine deacetylase	yodQ	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS2_k127_5679624_0	1220534.B655_0740	3.113e-112	386.0	arCOG02499@1|root,arCOG10865@1|root,arCOG02499@2157|Archaea,arCOG10865@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,NosD
LZS2_k127_5679624_2	1247963.JPHU01000022_gene84	3.33e-18	99.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	QU	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
LZS2_k127_5681774_1	926569.ANT_02620	1.201e-44	166.0	29AZZ@1|root,2ZXYX@2|Bacteria,2G8ZX@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5681774_2	926550.CLDAP_05830	2.733e-39	160.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	2.7.11.1,3.4.21.107,3.5.1.28	ko:K01448,ko:K04771,ko:K08884	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
LZS2_k127_5681774_5	1267535.KB906767_gene296	0.0004812	53.0	COG0457@1|root,COG0457@2|Bacteria,3Y4S2@57723|Acidobacteria	57723|Acidobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_8
LZS2_k127_5681774_3	326427.Cagg_2386	3.373e-19	98.0	2EQGV@1|root,33I2V@2|Bacteria,2G7HG@200795|Chloroflexi,375SC@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
LZS2_k127_5681774_4	326427.Cagg_0722	1.893e-06	53.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi,376R9@32061|Chloroflexia	32061|Chloroflexia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
LZS2_k127_5681774_0	926550.CLDAP_15350	3.289e-53	201.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
LZS2_k127_5687999_2	1380354.JIAN01000008_gene3313	3.822e-100	331.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
LZS2_k127_5687999_3	572547.Amico_1665	1.124e-80	274.0	COG0800@1|root,COG0800@2|Bacteria,3TAVM@508458|Synergistetes	508458|Synergistetes	G	PFAM KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
LZS2_k127_5687999_1	861299.J421_0376	1.471e-148	477.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
LZS2_k127_5687999_5	383372.Rcas_0166	1.494e-74	258.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi,375DQ@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS2_k127_5687999_6	926569.ANT_10810	1.191e-66	233.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
LZS2_k127_5687999_8	1076550.LH22_14525	1.224e-14	86.0	COG2390@1|root,COG2390@2|Bacteria,1R3QR@1224|Proteobacteria,1RPXW@1236|Gammaproteobacteria,3VZJ5@53335|Pantoea	1236|Gammaproteobacteria	K	Transcriptional regulator	deoR_1	-	-	-	-	-	-	-	-	-	-	-	MarR,Sugar-bind
LZS2_k127_5687999_10	1419814.V470_06145	6.399e-06	58.0	COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HNIW@91061|Bacilli	91061|Bacilli	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
LZS2_k127_5687999_0	1128421.JAGA01000003_gene3149	1.069e-220	700.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
LZS2_k127_5687999_4	439235.Dalk_4707	7.472e-75	259.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
LZS2_k127_5687999_7	1122603.ATVI01000006_gene59	8.158e-45	170.0	2E29H@1|root,32X6D@2|Bacteria,1QZRZ@1224|Proteobacteria,1T4AF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Acetoacetate decarboxylase (ADC)	-	-	-	-	-	-	-	-	-	-	-	-	ADC
LZS2_k127_5687999_9	1232437.KL662061_gene4157	5.909e-07	54.0	COG1280@1|root,COG1280@2|Bacteria,1Q4CV@1224|Proteobacteria,42TRD@68525|delta/epsilon subdivisions,2WVHX@28221|Deltaproteobacteria,2MPA8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
LZS2_k127_5695641_2	1449069.JMLO01000034_gene106	2.118e-09	62.0	COG1695@1|root,COG1695@2|Bacteria,2IHC2@201174|Actinobacteria,4G3NC@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
LZS2_k127_5695641_3	1123322.KB904691_gene4397	9.868e-07	53.0	COG4832@1|root,COG4832@2|Bacteria,2GN4K@201174|Actinobacteria	201174|Actinobacteria	K	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
LZS2_k127_5695641_1	1278073.MYSTI_02004	1.183e-80	281.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
LZS2_k127_5695641_4	643867.Ftrac_2926	8.922e-06	53.0	2E7WD@1|root,332B1@2|Bacteria,4P3PA@976|Bacteroidetes,47UUH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5695641_0	309801.trd_1791	4.725e-135	441.0	COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi	200795|Chloroflexi	J	SMART PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
LZS2_k127_5707371_4	222534.KB893715_gene1792	0.0005206	47.0	COG0842@1|root,COG0842@2|Bacteria,2I31D@201174|Actinobacteria,4EXC8@85013|Frankiales	201174|Actinobacteria	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5707371_1	926569.ANT_13330	7.116e-96	325.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_5707371_3	926550.CLDAP_23360	3.439e-45	173.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8QX@200795|Chloroflexi	200795|Chloroflexi	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
LZS2_k127_5707371_0	1382306.JNIM01000001_gene2717	2.451e-218	691.0	COG1012@1|root,COG1012@2|Bacteria,2G83P@200795|Chloroflexi	200795|Chloroflexi	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS2_k127_5707371_2	1122164.JHWF01000043_gene1435	1.502e-46	172.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,1JEMH@118969|Legionellales	118969|Legionellales	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
LZS2_k127_5713834_4	391595.RLO149_c021580	3.172e-06	49.0	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,2TSZ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS2_k127_5713834_0	391613.RTM1035_07013	7.862e-118	391.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,46PPX@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS2_k127_5713834_3	391595.RLO149_c021560	1.472e-83	293.0	COG4177@1|root,COG4177@2|Bacteria,1RD1T@1224|Proteobacteria,2UAJ3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG4177 ABC-type branched-chain amino acid transport system, permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS2_k127_5713834_1	391595.RLO149_c021550	2.046e-100	334.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TUQB@28211|Alphaproteobacteria,2P1T9@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
LZS2_k127_5713834_2	391595.RLO149_c021540	8.125e-95	317.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria,2P11B@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	MA20_22615	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
LZS2_k127_5713834_5	1304888.ATWF01000001_gene788	5.126e-06	52.0	COG0436@1|root,COG0436@2|Bacteria,2GENK@200930|Deferribacteres	200930|Deferribacteres	E	Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_5715376_5	357808.RoseRS_3588	1.066e-47	178.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi,37807@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA polymerase III, delta prime subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
LZS2_k127_5715376_4	926550.CLDAP_17850	6.666e-64	225.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	mshD	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
LZS2_k127_5715376_0	351607.Acel_1537	2.907e-124	412.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,4ERC5@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
LZS2_k127_5715376_2	383372.Rcas_2148	8.455e-99	344.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
LZS2_k127_5715376_1	926550.CLDAP_07930	8.033e-105	363.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
LZS2_k127_5715376_3	926550.CLDAP_24950	3.458e-79	286.0	COG0457@1|root,COG1846@1|root,COG0457@2|Bacteria,COG1846@2|Bacteria,2G9ET@200795|Chloroflexi	200795|Chloroflexi	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_5715927_1	1206741.BAFX01000075_gene3789	1.637e-80	293.0	2DQRE@1|root,3388X@2|Bacteria,2IBP8@201174|Actinobacteria,4G1YF@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5715927_2	933262.AXAM01000026_gene3091	2.366e-38	146.0	COG0614@1|root,COG0614@2|Bacteria,1MZ6W@1224|Proteobacteria,42W2Q@68525|delta/epsilon subdivisions,2WRCB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
LZS2_k127_5715927_0	926550.CLDAP_35150	0.0	1102.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
LZS2_k127_5716352_1	1122194.AUHU01000004_gene1343	1.883e-28	117.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,465HW@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the MurCDEF family	murC	GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iECP_1309.ECP_0093	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_5716352_0	926569.ANT_23380	1.068e-67	240.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
LZS2_k127_5721476_0	926569.ANT_14810	1.599e-270	854.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
LZS2_k127_5734040_0	926569.ANT_13470	2.463e-186	590.0	COG1233@1|root,COG1233@2|Bacteria,2G5ZA@200795|Chloroflexi	200795|Chloroflexi	C	PFAM amine oxidase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
LZS2_k127_5734040_1	926550.CLDAP_29060	3.96e-117	385.0	COG1562@1|root,COG1562@2|Bacteria,2G6KD@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Squalene phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
LZS2_k127_5734789_0	926569.ANT_28850	1.566e-57	202.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
LZS2_k127_5734789_2	768671.ThimaDRAFT_0362	0.0003357	51.0	COG2863@1|root,COG2863@2|Bacteria,1RBXV@1224|Proteobacteria,1SEAS@1236|Gammaproteobacteria,1X1G7@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS2_k127_5734789_1	1249627.D779_2842	5.645e-24	106.0	COG3381@1|root,COG3381@2|Bacteria,1N1T1@1224|Proteobacteria,1S9X5@1236|Gammaproteobacteria,1WZAE@135613|Chromatiales	135613|Chromatiales	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
LZS2_k127_5737060_7	926550.CLDAP_05320	2.863e-28	115.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
LZS2_k127_5737060_3	357808.RoseRS_3212	4.128e-126	422.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
LZS2_k127_5737060_1	357808.RoseRS_1075	4.269e-189	618.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_5737060_0	118163.Ple7327_2136	0.0	1515.0	COG0156@1|root,COG0604@1|root,COG3321@1|root,COG0156@2|Bacteria,COG0604@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,3VM40@52604|Pleurocapsales	1117|Cyanobacteria	CHQ	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2,AMP-binding,Acyl_transf_1,Aminotran_1_2,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
LZS2_k127_5737060_4	243090.RB9631	1.472e-76	274.0	COG1020@1|root,COG1020@2|Bacteria,2IZSG@203682|Planctomycetes	203682|Planctomycetes	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5737060_8	1449351.RISW2_15025	3.175e-10	70.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria	1224|Proteobacteria	IM	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
LZS2_k127_5737060_2	1123258.AQXZ01000011_gene1655	4.313e-140	466.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4G01K@85025|Nocardiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS2_k127_5737060_6	335543.Sfum_3525	1.661e-64	236.0	COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria,42Z3E@68525|delta/epsilon subdivisions,2WU93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
LZS2_k127_5737060_5	926569.ANT_15670	1.516e-75	281.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5737599_0	926550.CLDAP_37380	1.864e-169	542.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS2_k127_5737599_1	1499967.BAYZ01000028_gene1279	1.523e-133	441.0	COG0635@1|root,COG0635@2|Bacteria,2NRKI@2323|unclassified Bacteria	2|Bacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,NUDIX,Radical_SAM
LZS2_k127_5737599_2	1499967.BAYZ01000028_gene1280	2.182e-71	249.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
LZS2_k127_5737599_3	926550.CLDAP_13230	6.987e-16	89.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11,SBP_bac_6
LZS2_k127_5737599_4	765420.OSCT_2284	1.386e-05	53.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2G8ES@200795|Chloroflexi,3759V@32061|Chloroflexia	32061|Chloroflexia	P	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
LZS2_k127_5739610_2	926550.CLDAP_11690	3.042e-204	666.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi	200795|Chloroflexi	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
LZS2_k127_5739610_7	986075.CathTA2_1906	5.056e-64	222.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HGYP@91061|Bacilli	91061|Bacilli	M	Sortase and related acyltransferases	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
LZS2_k127_5739610_5	373994.Riv7116_5266	3.954e-74	261.0	COG3021@1|root,COG3021@2|Bacteria,1G9UD@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS2_k127_5739610_10	525904.Tter_1424	1.845e-54	201.0	COG0524@1|root,COG0524@2|Bacteria,2NRAA@2323|unclassified Bacteria	2|Bacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.3	ko:K00846	ko00051,ko01100,ko01120,map00051,map01100,map01120	-	R00866,R03819	RC00002,RC00017,RC00608	ko00000,ko00001,ko01000,ko04147	-	-	-	PfkB,Rieske
LZS2_k127_5739610_8	1521187.JPIM01000021_gene151	4.289e-58	213.0	COG1597@1|root,COG1597@2|Bacteria,2G70R@200795|Chloroflexi,375F4@32061|Chloroflexia	32061|Chloroflexia	I	diacylglycerol kinase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
LZS2_k127_5739610_3	357808.RoseRS_0195	4.508e-104	343.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,376TC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_5739610_4	420662.Mpe_A0106	6.595e-76	273.0	COG2304@1|root,COG2304@2|Bacteria,1N2UU@1224|Proteobacteria	1224|Proteobacteria	S	Von willebrand factor, type a	-	-	-	-	-	-	-	-	-	-	-	-	VWA
LZS2_k127_5739610_1	926569.ANT_01580	2.508e-302	951.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
LZS2_k127_5739610_0	443143.GM18_0718	5.267e-311	966.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS2_k127_5739610_6	111781.Lepto7376_1993	1.204e-72	251.0	2DCT2@1|root,32U08@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
LZS2_k127_5739610_9	1173024.KI912151_gene1625	6.365e-56	198.0	COG0058@1|root,COG0058@2|Bacteria,1FZUX@1117|Cyanobacteria,1JKQ6@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate phosphorylase	glgP	GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
LZS2_k127_575860_1	926550.CLDAP_24220	2.18e-148	477.0	28JDC@1|root,2Z97R@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
LZS2_k127_575860_0	926550.CLDAP_22400	0.0	1000.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c30720,ic_1306.c3371	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
LZS2_k127_575860_2	266117.Rxyl_1685	1.219e-126	415.0	COG1070@1|root,COG1070@2|Bacteria,2GISK@201174|Actinobacteria,4CPQB@84995|Rubrobacteria	84995|Rubrobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
LZS2_k127_5793988_2	880073.Calab_1228	2.929e-69	241.0	COG3634@1|root,COG3634@2|Bacteria,2NPR2@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
LZS2_k127_5793988_6	357808.RoseRS_0325	6.426e-39	152.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_5793988_12	357808.RoseRS_2794	1.731e-15	79.0	COG5660@1|root,COG5660@2|Bacteria,2G7CH@200795|Chloroflexi,3782G@32061|Chloroflexia	32061|Chloroflexia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS2_k127_5793988_5	926550.CLDAP_20580	2.169e-50	185.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
LZS2_k127_5793988_7	768671.ThimaDRAFT_0960	2.468e-32	138.0	2DMKI@1|root,32S70@2|Bacteria,1N1FV@1224|Proteobacteria,1THVW@1236|Gammaproteobacteria,1WZR5@135613|Chromatiales	135613|Chromatiales	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
LZS2_k127_5793988_9	1121091.AUMP01000021_gene3214	2.479e-23	111.0	COG1309@1|root,COG1309@2|Bacteria,1VDNV@1239|Firmicutes,4HKG8@91061|Bacilli	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
LZS2_k127_5793988_4	1123368.AUIS01000024_gene949	3.636e-53	201.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2NBU9@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_5793988_3	383372.Rcas_2358	5.769e-55	207.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
LZS2_k127_5793988_13	28042.GU90_12250	5.071e-14	79.0	COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria,4E4KM@85010|Pseudonocardiales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
LZS2_k127_5793988_11	1395587.P364_0116515	7.525e-17	85.0	2DP9D@1|root,31N9Y@2|Bacteria,1VG6X@1239|Firmicutes,4HWBT@91061|Bacilli,26Y9V@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5793988_14	1265505.ATUG01000001_gene3429	1.341e-13	76.0	COG1480@1|root,COG1480@2|Bacteria,1PB4H@1224|Proteobacteria	1224|Proteobacteria	S	7TM receptor with intracellular HD hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5793988_8	768704.Desmer_0694	1.14e-27	120.0	COG1309@1|root,COG1309@2|Bacteria,1VBD4@1239|Firmicutes,25BAD@186801|Clostridia,263B7@186807|Peptococcaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS2_k127_5793988_1	357808.RoseRS_2479	7.142e-101	340.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
LZS2_k127_5793988_0	926550.CLDAP_07720	3.255e-105	353.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
LZS2_k127_5793988_15	1206739.BAGJ01000086_gene468	2.451e-12	78.0	COG0702@1|root,COG0702@2|Bacteria,2HBFK@201174|Actinobacteria,4FYKG@85025|Nocardiaceae	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
LZS2_k127_5796267_1	309801.trd_0379	6.352e-87	299.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
LZS2_k127_5796267_0	926550.CLDAP_18370	5.113e-144	460.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
LZS2_k127_5796267_2	1128421.JAGA01000002_gene1806	3.267e-75	257.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
LZS2_k127_5811440_2	530564.Psta_1560	2.946e-73	262.0	2EW1S@1|root,33PF1@2|Bacteria,2J1T5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5811440_1	1121373.KB903662_gene63	3.723e-155	493.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,47JCC@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
LZS2_k127_5811440_0	1499967.BAYZ01000086_gene5166	3.293e-260	817.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2NPBJ@2323|unclassified Bacteria	2|Bacteria	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
LZS2_k127_5811440_3	926550.CLDAP_00520	5.365e-42	160.0	2DMUR@1|root,32TTD@2|Bacteria,2G72Z@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
LZS2_k127_5811440_5	1347086.CCBA010000039_gene4919	2.191e-07	57.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,1ZGXM@1386|Bacillus	91061|Bacilli	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_5811440_4	1499967.BAYZ01000085_gene5178	1.173e-17	98.0	COG1807@1|root,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_5844988_3	926569.ANT_08940	1.534e-05	56.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_5844988_1	316274.Haur_4061	7.077e-62	242.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS2_k127_5844988_0	926550.CLDAP_00920	2.194e-110	388.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi	200795|Chloroflexi	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
LZS2_k127_5844988_2	751945.Theos_1990	6.078e-22	100.0	COG0824@1|root,COG0824@2|Bacteria,1WKH6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
LZS2_k127_584513_3	357808.RoseRS_2735	6.758e-21	93.0	COG3408@1|root,COG3408@2|Bacteria,2G7KB@200795|Chloroflexi,376HX@32061|Chloroflexia	32061|Chloroflexia	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
LZS2_k127_584513_6	1071073.KI530540_gene3360	0.0008198	50.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HRBT@91061|Bacilli,1ZISZ@1386|Bacillus	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	xre	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
LZS2_k127_584513_1	324602.Caur_0703	8.06e-92	323.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
LZS2_k127_584513_5	68170.KL590503_gene350	0.00013	51.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DXAK@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_10,TPR_12,Trans_reg_C
LZS2_k127_584513_2	272558.10173898	4.299e-23	109.0	COG1404@1|root,COG1404@2|Bacteria,1V3SC@1239|Firmicutes,4HFE4@91061|Bacilli,1ZF22@1386|Bacillus	91061|Bacilli	O	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397,Gram_pos_anchor
LZS2_k127_584513_4	357808.RoseRS_3119	9.145e-20	96.0	COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi,375JA@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase C60, sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
LZS2_k127_584513_0	926569.ANT_16840	2.339e-302	952.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS2_k127_5848100_0	926569.ANT_03530	1.966e-253	799.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS2_k127_5848100_2	926569.ANT_03490	4.31e-51	190.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
LZS2_k127_5848100_1	926550.CLDAP_22220	1.896e-106	362.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS2_k127_5865297_5	926550.CLDAP_30360	3.57e-62	233.0	COG3391@1|root,COG5305@1|root,COG3391@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_5865297_10	926550.CLDAP_05830	3.265e-06	58.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	2.7.11.1,3.4.21.107,3.5.1.28	ko:K01448,ko:K04771,ko:K08884	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
LZS2_k127_5865297_8	580327.Tthe_1130	4.947e-11	66.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,42GYW@68295|Thermoanaerobacterales	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
LZS2_k127_5865297_3	649638.Trad_1483	3.007e-65	232.0	COG0647@1|root,COG0647@2|Bacteria,1WMXZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	COGs COG0647 sugar phosphatase of the HAD superfamily	-	-	3.1.3.41	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
LZS2_k127_5865297_4	1173027.Mic7113_1271	2.419e-64	222.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1HB1V@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
LZS2_k127_5865297_6	861299.J421_0777	6.307e-52	186.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
LZS2_k127_5865297_0	335543.Sfum_2837	1.157e-87	308.0	COG4191@1|root,COG4251@1|root,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,42QA2@68525|delta/epsilon subdivisions,2X7QC@28221|Deltaproteobacteria,2MQRX@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE3,PAS_9
LZS2_k127_5865297_2	485913.Krac_5625	2.859e-79	270.0	COG0400@1|root,COG0400@2|Bacteria,2G8M6@200795|Chloroflexi	200795|Chloroflexi	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
LZS2_k127_5865297_1	926569.ANT_21060	5.123e-82	287.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
LZS2_k127_5865297_7	1122128.AUEE01000001_gene2112	8.103e-26	119.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,4GXWK@90964|Staphylococcaceae	91061|Bacilli	S	Required for morphogenesis under gluconeogenic growth conditions	yvcK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
LZS2_k127_5865297_12	351348.Maqu_3353	7.671e-05	46.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,464J6@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS2_k127_5872545_10	373903.Hore_14980	1.4e-36	143.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,24BQ6@186801|Clostridia	186801|Clostridia	S	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721,ko:K00786	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS2_k127_5872545_9	926550.CLDAP_25240	1.015e-44	173.0	COG1547@1|root,COG3437@1|root,COG1547@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309,HD
LZS2_k127_5872545_4	1122939.ATUD01000006_gene1641	8.957e-57	207.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CPX6@84995|Rubrobacteria	84995|Rubrobacteria	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_5872545_7	926569.ANT_30110	1.142e-49	186.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
LZS2_k127_5872545_1	926550.CLDAP_31730	2.07e-174	574.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
LZS2_k127_5872545_3	525904.Tter_0035	3.684e-67	235.0	COG0311@1|root,COG0311@2|Bacteria,2NPDR@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
LZS2_k127_5872545_12	479431.Namu_4321	7.311e-07	57.0	COG0494@1|root,COG0494@2|Bacteria,2I2GY@201174|Actinobacteria,4ET93@85013|Frankiales	201174|Actinobacteria	L	Nudix hydrolase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_5872545_6	314230.DSM3645_05160	4.809e-50	184.0	COG0637@1|root,COG0637@2|Bacteria,2IZIM@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS2_k127_5872545_2	1293054.HSACCH_00330	1.34e-70	247.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,3WAJM@53433|Halanaerobiales	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
LZS2_k127_5872545_0	1499967.BAYZ01000069_gene1884	6.516e-183	579.0	COG1089@1|root,COG1089@2|Bacteria,2NNM2@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS2_k127_5872545_8	1283300.ATXB01000001_gene513	3.566e-48	179.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,1S02F@1236|Gammaproteobacteria,1XEH3@135618|Methylococcales	135618|Methylococcales	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
LZS2_k127_5872545_5	98439.AJLL01000051_gene3523	1.095e-54	204.0	COG0451@1|root,COG0451@2|Bacteria,1G48D@1117|Cyanobacteria,1JJN9@1189|Stigonemataceae	1117|Cyanobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS2_k127_5872545_11	926569.ANT_03640	1.079e-14	78.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS2_k127_5877043_1	926550.CLDAP_37610	3.634e-21	97.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
LZS2_k127_5877043_0	926550.CLDAP_30400	1.698e-262	851.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
LZS2_k127_5881613_1	316274.Haur_0218	9.132e-235	739.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
LZS2_k127_5881613_5	10224.XP_002741735.1	7.179e-35	141.0	COG1428@1|root,KOG4235@2759|Eukaryota,38FI8@33154|Opisthokonta,3BABN@33208|Metazoa,3CZXP@33213|Bilateria	33208|Metazoa	F	thymidine kinase 2, mitochondrial	TK2	GO:0000002,GO:0003674,GO:0003824,GO:0004137,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006165,GO:0006213,GO:0006220,GO:0006221,GO:0006230,GO:0006259,GO:0006260,GO:0006261,GO:0006264,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009059,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009132,GO:0009156,GO:0009157,GO:0009161,GO:0009162,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009262,GO:0009987,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0031974,GO:0032042,GO:0034404,GO:0034641,GO:0034645,GO:0034654,GO:0043094,GO:0043097,GO:0043170,GO:0043174,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046044,GO:0046092,GO:0046104,GO:0046125,GO:0046134,GO:0046390,GO:0046483,GO:0046939,GO:0055086,GO:0070013,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0090304,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.145,2.7.1.21	ko:K00857,ko:K05961	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	dNK
LZS2_k127_5881613_0	926550.CLDAP_14400	7.564e-305	951.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2G65R@200795|Chloroflexi	200795|Chloroflexi	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,malic
LZS2_k127_5881613_6	1499967.BAYZ01000123_gene2553	4.564e-19	87.0	COG4231@1|root,COG4231@2|Bacteria	2|Bacteria	C	indolepyruvate ferredoxin oxidoreductase activity	-	-	1.2.7.8	ko:K00179,ko:K05524	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR,POR_N,TPP_enzyme_C
LZS2_k127_5881613_3	452637.Oter_1799	8.132e-48	175.0	2C7QB@1|root,341QI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5881613_4	1035308.AQYY01000001_gene1201	3.593e-35	149.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,SpoIIM
LZS2_k127_5881613_2	1536772.R70723_06045	1.819e-94	319.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,26TFZ@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_5881613_7	479434.Sthe_3364	5.123e-09	65.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,27Z1H@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_5896537_1	926550.CLDAP_04470	7.346e-86	315.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5896537_2	926550.CLDAP_21460	8.637e-75	258.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
LZS2_k127_5896537_3	1227457.C451_20612	1.34e-30	131.0	COG0299@1|root,arCOG02825@2157|Archaea,2Y060@28890|Euryarchaeota,23YGI@183963|Halobacteria	183963|Halobacteria	F	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
LZS2_k127_5896537_0	926550.CLDAP_21470	3.293e-137	446.0	COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_5900453_1	926550.CLDAP_36460	1.323e-253	788.0	COG3534@1|root,COG3534@2|Bacteria,2G63U@200795|Chloroflexi	200795|Chloroflexi	G	PFAM alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
LZS2_k127_5900453_0	1134912.AJTV01000021_gene3004	1.647e-296	934.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,2U2CB@28211|Alphaproteobacteria,36YRU@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
LZS2_k127_5900453_3	926560.KE387026_gene4278	1.095e-37	158.0	COG1653@1|root,COG1653@2|Bacteria,1WJIN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
LZS2_k127_5900453_2	443143.GM18_4304	6.314e-64	229.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_5912770_1	926550.CLDAP_06140	3.087e-28	116.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS2_k127_5912770_0	357808.RoseRS_1829	6.737e-150	484.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,374WW@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS2_k127_5912770_3	926550.CLDAP_11920	4.063e-19	104.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,PTPS_related
LZS2_k127_5912770_2	926550.CLDAP_01930	6.655e-22	106.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
LZS2_k127_5919890_0	926550.CLDAP_16810	2.154e-87	295.0	COG0621@1|root,COG0621@2|Bacteria,2G5ZJ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
LZS2_k127_5919890_1	880073.Calab_3479	2.633e-22	97.0	COG3118@1|root,COG3118@2|Bacteria,2NPNZ@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_5922263_3	926569.ANT_03740	1.568e-86	293.0	COG1116@1|root,COG1116@2|Bacteria,2G8SU@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
LZS2_k127_5922263_4	926569.ANT_03730	2.744e-81	278.0	COG0600@1|root,COG0600@2|Bacteria,2G72A@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
LZS2_k127_5922263_8	926550.CLDAP_31390	3.042e-68	255.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926550.CLDAP_31390|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5922263_6	357808.RoseRS_1818	1.414e-74	260.0	COG3118@1|root,COG3118@2|Bacteria,2G90Y@200795|Chloroflexi,376KV@32061|Chloroflexia	32061|Chloroflexia	O	PFAM Thioredoxin domain	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
LZS2_k127_5922263_16	649747.HMPREF0083_04065	1.298e-17	91.0	COG3682@1|root,COG3682@2|Bacteria,1V8I7@1239|Firmicutes,4HJ6A@91061|Bacilli,26XN4@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
LZS2_k127_5922263_1	1499967.BAYZ01000116_gene3144	1.663e-185	595.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	BLUF,GAF_2,GAF_3,Guanylate_cyc,HAMP,HATPase_c,HisKA,Response_reg
LZS2_k127_5922263_11	1304872.JAGC01000009_gene482	1.243e-40	165.0	COG4191@1|root,COG4191@2|Bacteria,1P0U1@1224|Proteobacteria,42PTP@68525|delta/epsilon subdivisions,2WJ8U@28221|Deltaproteobacteria,2M8NY@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_5922263_15	1033734.CAET01000063_gene1989	1.756e-23	109.0	COG2197@1|root,COG2197@2|Bacteria,1TSBV@1239|Firmicutes,4HC74@91061|Bacilli,1ZC5P@1386|Bacillus	91061|Bacilli	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	nreC	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_5922263_12	1288.SXYLSMQ121_1113	9.771e-39	162.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,4GXKP@90964|Staphylococcaceae	91061|Bacilli	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
LZS2_k127_5922263_2	1396418.BATQ01000049_gene417	2.063e-115	403.0	COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,46UHX@74201|Verrucomicrobia,2IVRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
LZS2_k127_5922263_7	1297742.A176_04659	2.704e-71	243.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42VIG@68525|delta/epsilon subdivisions,2WS98@28221|Deltaproteobacteria,2YV93@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_5922263_9	1121403.AUCV01000013_gene3928	6.881e-62	217.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42T9C@68525|delta/epsilon subdivisions,2WP3Z@28221|Deltaproteobacteria,2MKTX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_5922263_13	111780.Sta7437_3706	7.695e-30	139.0	COG0745@1|root,COG2199@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1G2A0@1117|Cyanobacteria,3VMDE@52604|Pleurocapsales	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,Response_reg
LZS2_k127_5922263_5	1128421.JAGA01000003_gene3053	1.56e-80	306.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg,dCache_1
LZS2_k127_5922263_10	883.DvMF_2543	3.752e-43	161.0	COG0745@1|root,COG0745@2|Bacteria,1PDU9@1224|Proteobacteria,43EXZ@68525|delta/epsilon subdivisions,2X2IY@28221|Deltaproteobacteria,2MD8C@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_5922263_14	926550.CLDAP_39800	5.364e-24	104.0	COG0745@1|root,COG0745@2|Bacteria	926550.CLDAP_39800|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5922263_0	926569.ANT_27120	4.478e-216	695.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
LZS2_k127_5931324_3	1335760.ASTG01000016_gene97	8.928e-32	134.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2K23Q@204457|Sphingomonadales	204457|Sphingomonadales	M	NAD-dependent epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
LZS2_k127_5931324_6	909663.KI867150_gene2308	1.371e-23	110.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	Methyltransf_25,PhyH,TPR_11,UbiA
LZS2_k127_5931324_1	880073.Calab_2319	2.621e-76	266.0	COG1216@1|root,COG1216@2|Bacteria,2NR8Z@2323|unclassified Bacteria	2|Bacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_5931324_2	1172188.KB911820_gene3023	2.918e-70	257.0	COG1690@1|root,COG1690@2|Bacteria,2IBHP@201174|Actinobacteria,4FIRQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	-	-	-	-	-	-	-	-	-	-	RtcB
LZS2_k127_5931324_5	445335.CBN_3152	6.323e-30	135.0	COG2244@1|root,COG2244@2|Bacteria,1V8VR@1239|Firmicutes,24BD7@186801|Clostridia,36EVG@31979|Clostridiaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS2_k127_5931324_4	880073.Calab_2324	2.24e-31	136.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	Methyltransf_25,PhyH,TPR_11,UbiA
LZS2_k127_5931324_7	1121377.KB906404_gene2848	3.458e-14	87.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,FAD_oxidored,HI0933_like,Lycopene_cycl
LZS2_k127_5931324_0	398512.JQKC01000004_gene5249	2.667e-99	353.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,3WI29@541000|Ruminococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS2_k127_5950217_5	1265505.ATUG01000002_gene1243	1.315e-68	240.0	COG3829@1|root,COG3829@2|Bacteria,1N0KJ@1224|Proteobacteria,42YX7@68525|delta/epsilon subdivisions,2WUG8@28221|Deltaproteobacteria,2MMI5@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5950217_7	443143.GM18_0068	8.729e-62	235.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HAMP,HATPase_c,HisKA
LZS2_k127_5950217_6	309799.DICTH_1024	4.358e-67	241.0	COG1744@1|root,COG1744@2|Bacteria	2|Bacteria	ET	ABC transporter substrate-binding protein PnrA-like	bmpA	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
LZS2_k127_5950217_0	765420.OSCT_1228	1.744e-120	415.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_5950217_1	1499967.BAYZ01000026_gene1633	4.103e-101	347.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF3404,HATPase_c,HisKA,PAS_8,Response_reg
LZS2_k127_5950217_9	338969.Rfer_0897	1.919e-24	109.0	COG2197@1|root,COG2197@2|Bacteria,1N5IE@1224|Proteobacteria,2W4QA@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_5950217_2	338969.Rfer_0894	1.553e-74	257.0	COG2197@1|root,COG2197@2|Bacteria,1RH8D@1224|Proteobacteria,2WEH4@28216|Betaproteobacteria,4AIYX@80864|Comamonadaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_5950217_3	118166.JH976538_gene5065	3.04e-70	263.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_5950217_10	443143.GM18_0071	5.931e-23	115.0	COG2199@1|root,COG3706@2|Bacteria,1PBPS@1224|Proteobacteria	1224|Proteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HDOD
LZS2_k127_5950217_4	926569.ANT_09090	9.238e-70	254.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G89B@200795|Chloroflexi	200795|Chloroflexi	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBP_BcsQ,Response_reg
LZS2_k127_5950217_8	118168.MC7420_821	7.768e-35	144.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1H7H2@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_5959201_1	1173027.Mic7113_4322	1.034e-141	469.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
LZS2_k127_5959201_2	525904.Tter_2526	2.538e-79	282.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_5959201_0	63737.Npun_F1222	4.958e-234	774.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HINJ@1161|Nostocales	1117|Cyanobacteria	L	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
LZS2_k127_5977709_0	316274.Haur_4489	1.396e-116	388.0	COG0438@1|root,COG0438@2|Bacteria,2G67A@200795|Chloroflexi,374TH@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_5977709_1	316274.Haur_0149	9.794e-13	78.0	COG1051@1|root,COG1051@2|Bacteria,2G9MA@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS2_k127_5979169_3	1303518.CCALI_01986	7.433e-56	209.0	COG3605@1|root,COG3920@1|root,COG3605@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17,4.2.1.75,4.6.1.1	ko:K00936,ko:K01719,ko:K01768,ko:K02030,ko:K02584,ko:K10441,ko:K13924,ko:K20962	ko00230,ko00860,ko01100,ko01110,ko01120,ko02010,ko02020,ko02025,ko02030,ko04113,ko04213,ko05111,map00230,map00860,map01100,map01110,map01120,map02010,map02020,map02025,map02030,map04113,map04213,map05111	M00121,M00212,M00236,M00506,M00695,M00839	R00089,R00434,R03165	RC00295,RC01861	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035,ko03000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.3	-	-	GAF,GAF_2,HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12,TPR_8
LZS2_k127_5979169_0	867845.KI911784_gene3063	9.673e-130	422.0	COG1085@1|root,COG1085@2|Bacteria,2G6K5@200795|Chloroflexi,376AM@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM galactose-1-phosphate uridylyltransferase	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
LZS2_k127_5979169_1	926569.ANT_20980	1.512e-94	318.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
LZS2_k127_5979169_2	926569.ANT_20970	2.598e-91	310.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K09820,ko:K11710	ko02010,map02010	M00243,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
LZS2_k127_5985142_2	1122194.AUHU01000003_gene2398	6.42e-67	232.0	COG4977@1|root,COG4977@2|Bacteria,1QUTN@1224|Proteobacteria,1T2UV@1236|Gammaproteobacteria,466W0@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	DJ-1/PfpI family	inhA	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
LZS2_k127_5985142_4	468059.AUHA01000006_gene2864	5.417e-60	212.0	COG4297@1|root,COG4297@2|Bacteria,4NNG0@976|Bacteroidetes,1ISDM@117747|Sphingobacteriia	976|Bacteroidetes	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
LZS2_k127_5985142_3	926550.CLDAP_12690	3.697e-64	224.0	COG3059@1|root,COG3059@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
LZS2_k127_5985142_5	1121091.AUMP01000008_gene3560	2.985e-44	165.0	COG2363@1|root,COG2363@2|Bacteria,1VA79@1239|Firmicutes,4HKHG@91061|Bacilli	91061|Bacilli	S	membrane	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
LZS2_k127_5985142_0	1173027.Mic7113_5585	4.172e-193	613.0	COG1252@1|root,COG1252@2|Bacteria,1G20T@1117|Cyanobacteria,1H80B@1150|Oscillatoriales	1117|Cyanobacteria	C	NADH dehydrogenase, FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS2_k127_5985142_1	56110.Oscil6304_3914	1.085e-79	269.0	COG2343@1|root,COG2343@2|Bacteria,1G50P@1117|Cyanobacteria,1HAMP@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG2343 conserved	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
LZS2_k127_5987447_4	926569.ANT_10850	5.901e-76	275.0	COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636,ko:K07642	ko02020,map02020	M00434,M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
LZS2_k127_5987447_2	760568.Desku_2298	1.108e-92	314.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
LZS2_k127_5987447_0	1382304.JNIL01000001_gene648	1.658e-132	435.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF_1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS2_k127_5987447_7	926569.ANT_11720	2.693e-17	91.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NERD
LZS2_k127_5987447_10	926550.CLDAP_00150	0.0001093	54.0	COG0664@1|root,COG0664@2|Bacteria,2G902@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_6,Fer4_7,cNMP_binding
LZS2_k127_5987447_11	218284.CCDN010000001_gene445	0.0003345	53.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,1ZD6Z@1386|Bacillus	91061|Bacilli	M	cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,Collagen_bind,Gram_pos_anchor,MucBP
LZS2_k127_5987447_1	926550.CLDAP_16330	3.4e-131	447.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_5987447_3	518766.Rmar_1354	2.902e-79	273.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,1FJ00@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
LZS2_k127_5987447_5	621372.ACIH01000113_gene910	4.114e-47	173.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli,26Y3E@186822|Paenibacillaceae	91061|Bacilli	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS2_k127_5987447_6	1051501.AYTL01000028_gene1966	1.893e-26	111.0	COG1695@1|root,COG1695@2|Bacteria,1V4NA@1239|Firmicutes,4HHWW@91061|Bacilli,1ZINR@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
LZS2_k127_5987447_9	1423321.AS29_06460	6.375e-06	54.0	COG0772@1|root,COG0772@2|Bacteria,1V1V4@1239|Firmicutes,4HCZ8@91061|Bacilli,1ZDCU@1386|Bacillus	91061|Bacilli	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
LZS2_k127_5992770_5	1304880.JAGB01000001_gene466	1.121e-79	271.0	COG1896@1|root,COG1896@2|Bacteria,1TSDU@1239|Firmicutes,24FT8@186801|Clostridia	186801|Clostridia	S	HD domain protein	yfbR	-	3.1.3.89	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	-	R01569,R01664,R01968,R02088,R02102,R10776	RC00017	ko00000,ko00001,ko01000	-	-	-	HD_2,HD_3
LZS2_k127_5992770_7	565033.GACE_1665	9.031e-24	116.0	COG1233@1|root,arCOG01521@2157|Archaea,2XUA0@28890|Euryarchaeota,245V6@183980|Archaeoglobi	183980|Archaeoglobi	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
LZS2_k127_5992770_9	387631.Asulf_01139	4.136e-07	63.0	COG2768@1|root,arCOG02448@2157|Archaea	2157|Archaea	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	Fer4
LZS2_k127_5992770_4	926550.CLDAP_06250	7.178e-86	301.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MFS_1
LZS2_k127_5992770_3	479434.Sthe_1657	2.985e-106	352.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,27XEG@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
LZS2_k127_5992770_8	1303518.CCALI_00427	1.225e-19	95.0	COG0745@1|root,COG0745@2|Bacteria	1303518.CCALI_00427|-	T	phosphorelay signal transduction system	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
LZS2_k127_5992770_2	518766.Rmar_1923	3.184e-120	397.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1FISB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
LZS2_k127_5992770_0	357808.RoseRS_2859	1.308e-151	487.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,3771P@32061|Chloroflexia	32061|Chloroflexia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS2_k127_5992770_6	383372.Rcas_2439	6.397e-64	229.0	COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi,37765@32061|Chloroflexia	32061|Chloroflexia	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5992770_1	1385935.N836_19490	8.562e-134	439.0	COG3464@1|root,COG3464@2|Bacteria,1G9CU@1117|Cyanobacteria,1HGU0@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6018556_0	926569.ANT_31010	1.841e-77	263.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS2_k127_6018556_1	1540257.JQMW01000009_gene3574	1.585e-72	253.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,36DEJ@31979|Clostridiaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
LZS2_k127_6046026_10	926569.ANT_22440	2.223e-54	207.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
LZS2_k127_6046026_12	316274.Haur_1623	7.647e-27	115.0	COG2172@1|root,COG2172@2|Bacteria,2GBV4@200795|Chloroflexi,375TN@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
LZS2_k127_6046026_11	357808.RoseRS_3288	7.663e-40	151.0	COG1366@1|root,COG1366@2|Bacteria,2G9K5@200795|Chloroflexi,375MW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS
LZS2_k127_6046026_5	269799.Gmet_3033	2.178e-108	363.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,43SVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
LZS2_k127_6046026_15	1095750.HMPREF9970_1683	4.511e-11	70.0	COG1357@1|root,COG1357@2|Bacteria,1VPY1@1239|Firmicutes,24WKX@186801|Clostridia	186801|Clostridia	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_6046026_1	666681.M301_1373	3.699e-245	777.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,2KMDN@206350|Nitrosomonadales	206350|Nitrosomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
LZS2_k127_6046026_0	864702.OsccyDRAFT_1674	2.555e-275	869.0	COG0474@1|root,COG0474@2|Bacteria,1G3BZ@1117|Cyanobacteria,1H8N0@1150|Oscillatoriales	1117|Cyanobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
LZS2_k127_6046026_13	215803.DB30_1486	2.129e-19	90.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42NI6@68525|delta/epsilon subdivisions,2WKI1@28221|Deltaproteobacteria,2YXY1@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
LZS2_k127_6046026_7	1120971.AUCA01000015_gene325	1.793e-101	340.0	COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HBKZ@91061|Bacilli	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
LZS2_k127_6046026_14	926569.ANT_00160	7.311e-14	80.0	28U8H@1|root,2ZGE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6046026_17	690850.Desaf_3596	0.0001063	47.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,42NXE@68525|delta/epsilon subdivisions,2WKS4@28221|Deltaproteobacteria,2M9FG@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	PFAM Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_6046026_6	926569.ANT_22600	3.703e-102	351.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
LZS2_k127_6046026_4	1173028.ANKO01000250_gene2370	3.27e-130	431.0	COG0477@1|root,COG2814@2|Bacteria,1GQ8C@1117|Cyanobacteria,1HH9P@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_6046026_8	1382306.JNIM01000001_gene527	1.269e-81	278.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_6046026_2	383372.Rcas_0946	9.204e-197	621.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi,374V0@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS2_k127_6046026_3	926550.CLDAP_15240	1.928e-167	537.0	COG0448@1|root,COG0448@2|Bacteria,2G7W8@200795|Chloroflexi	200795|Chloroflexi	H	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS2_k127_6046026_9	1234664.AMRO01000077_gene3290	1.782e-56	202.0	COG2320@1|root,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,4HH5X@91061|Bacilli,1WFQD@129337|Geobacillus	91061|Bacilli	S	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
LZS2_k127_6046026_16	1449063.JMLS01000005_gene3101	4.608e-10	65.0	COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes	1239|Firmicutes	T	hydrolase (HAD superfamily)	-	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS2_k127_6049671_1	1121875.KB907548_gene1502	3.757e-112	371.0	COG0407@1|root,COG0407@2|Bacteria,4P05Q@976|Bacteroidetes	976|Bacteroidetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
LZS2_k127_6049671_2	1287276.X752_07205	4.453e-41	155.0	COG3602@1|root,COG3602@2|Bacteria,1MZKQ@1224|Proteobacteria,2U85U@28211|Alphaproteobacteria,43KM6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	ACT domain	-	-	-	ko:K09964	-	-	-	-	ko00000	-	-	-	ACT_3,ACT_7
LZS2_k127_6049671_0	156889.Mmc1_2685	1.224e-120	426.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
LZS2_k127_6049671_3	1173264.KI913949_gene41	4.158e-39	150.0	COG0726@1|root,COG0726@2|Bacteria,1G5ZR@1117|Cyanobacteria	1117|Cyanobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS2_k127_6075773_0	56107.Cylst_1531	0.0	1200.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HKNU@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_25,PP-binding,Thioesterase
LZS2_k127_6075773_1	1499967.BAYZ01000009_gene5353	1.236e-310	991.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	HEAT_2,HTH_Crp_2,cNMP_binding
LZS2_k127_6075773_14	33876.JNXY01000039_gene6584	4.771e-17	82.0	28VCT@1|root,2ZHFH@2|Bacteria,2GPRW@201174|Actinobacteria,4DFCX@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6075773_5	56107.Cylst_1905	1.208e-104	346.0	COG0455@1|root,COG0455@2|Bacteria,1G1EJ@1117|Cyanobacteria,1HQDQ@1161|Nostocales	1117|Cyanobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA
LZS2_k127_6075773_9	382464.ABSI01000013_gene1570	4.467e-61	241.0	COG2114@1|root,COG3899@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,46U27@74201|Verrucomicrobia	74201|Verrucomicrobia	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
LZS2_k127_6075773_18	246969.TAM4_1366	6.426e-12	76.0	COG0524@1|root,arCOG00014@2157|Archaea,2Y67H@28890|Euryarchaeota,2431X@183968|Thermococci	183968|Thermococci	G	Belongs to the carbohydrate kinase PfkB family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704	2.7.1.213	ko:K21057	ko00240,map00240	-	R00513,R00964,R01666	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS2_k127_6075773_12	926550.CLDAP_03020	7.331e-27	117.0	COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi	200795|Chloroflexi	M	peptidase C60 sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
LZS2_k127_6075773_16	502025.Hoch_5658	1.144e-13	78.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1R91W@1224|Proteobacteria,42PXP@68525|delta/epsilon subdivisions,2WJJX@28221|Deltaproteobacteria,2YX85@29|Myxococcales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_9
LZS2_k127_6075773_8	1128421.JAGA01000004_gene2493	7.095e-71	260.0	COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M1 domain	pepN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
LZS2_k127_6075773_6	357808.RoseRS_1337	8.718e-104	343.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,375BD@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_6075773_13	1347392.CCEZ01000017_gene1159	8.633e-18	98.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,36FZK@31979|Clostridiaceae	186801|Clostridia	M	family 25	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
LZS2_k127_6075773_7	279714.FuraDRAFT_2532	6.775e-87	315.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,2VPH9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
LZS2_k127_6075773_11	1157490.EL26_22525	8.776e-42	156.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,279UH@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
LZS2_k127_6075773_15	926569.ANT_00600	5.499e-16	79.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
LZS2_k127_6075773_10	1196028.ALEF01000029_gene1754	3.622e-53	192.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HFUS@91061|Bacilli,4C4SX@84406|Virgibacillus	91061|Bacilli	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
LZS2_k127_6075773_4	357808.RoseRS_4187	3.116e-111	368.0	COG1494@1|root,COG1494@2|Bacteria,2G5XR@200795|Chloroflexi,37645@32061|Chloroflexia	32061|Chloroflexia	G	TIGRFAM fructose-1,6-bisphosphatase, class II	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
LZS2_k127_6075773_2	926550.CLDAP_30450	1.308e-224	717.0	COG0607@1|root,COG0659@1|root,COG0607@2|Bacteria,COG0659@2|Bacteria,2G83D@200795|Chloroflexi	200795|Chloroflexi	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Rhodanese,STAS,Sulfate_transp
LZS2_k127_6075773_3	765420.OSCT_2904	1.874e-197	637.0	COG0607@1|root,COG0659@1|root,COG0607@2|Bacteria,COG0659@2|Bacteria,2G83D@200795|Chloroflexi,3764C@32061|Chloroflexia	32061|Chloroflexia	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Rhodanese,STAS,Sulfate_transp
LZS2_k127_6075773_17	765420.OSCT_2904	2.911e-13	72.0	COG0607@1|root,COG0659@1|root,COG0607@2|Bacteria,COG0659@2|Bacteria,2G83D@200795|Chloroflexi,3764C@32061|Chloroflexia	32061|Chloroflexia	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Rhodanese,STAS,Sulfate_transp
LZS2_k127_6079657_1	383372.Rcas_1699	4.72e-80	275.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,375G0@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS2_k127_6079657_0	926550.CLDAP_13110	5.5e-110	364.0	COG1216@1|root,COG1216@2|Bacteria,2G66T@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_6079657_2	387631.Asulf_01034	7.398e-15	84.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,24607@183980|Archaeoglobi	183980|Archaeoglobi	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
LZS2_k127_6090547_6	926690.KE386573_gene2449	3.819e-14	79.0	COG0616@1|root,arCOG01311@2157|Archaea,2XUZ2@28890|Euryarchaeota,23V1R@183963|Halobacteria	183963|Halobacteria	O	COG0616 Periplasmic serine proteases (ClpP class)	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS2_k127_6090547_5	926550.CLDAP_09600	1.808e-26	127.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	Collagen
LZS2_k127_6090547_2	1121918.ARWE01000001_gene1111	8.637e-81	292.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43S4Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
LZS2_k127_6090547_3	936455.KI421499_gene334	2.408e-71	254.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQJC@28211|Alphaproteobacteria,3JU9K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	MA20_01205	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_6090547_4	324602.Caur_2782	1.255e-55	209.0	COG1173@1|root,COG1173@2|Bacteria,2G853@200795|Chloroflexi	200795|Chloroflexi	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_6090547_1	981383.AEWH01000018_gene3206	2.428e-185	591.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli	91061|Bacilli	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
LZS2_k127_6090547_0	670487.Ocepr_0685	3.414e-213	682.0	COG0046@1|root,COG0047@1|root,COG1828@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,COG1828@2|Bacteria,1WIR9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS2_k127_6095268_2	1128421.JAGA01000002_gene86	4.128e-25	104.0	COG1975@1|root,COG1975@2|Bacteria	2|Bacteria	O	molybdopterin cofactor binding	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
LZS2_k127_6095268_1	357808.RoseRS_0501	2.444e-66	235.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi,37650@32061|Chloroflexia	32061|Chloroflexia	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
LZS2_k127_6095268_0	1487953.JMKF01000045_gene2899	1.356e-178	572.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	tri	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
LZS2_k127_6097324_2	926550.CLDAP_17520	1.117e-06	52.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_6097324_0	926550.CLDAP_39750	7.019e-67	256.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
LZS2_k127_6097324_1	765420.OSCT_1750	3.127e-13	83.0	COG1807@1|root,COG1807@2|Bacteria,2GAPY@200795|Chloroflexi,376ZD@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_6097324_3	284031.JNXD01000035_gene4112	1.222e-05	57.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
LZS2_k127_6100812_1	1499967.BAYZ01000104_gene3618	1.305e-194	611.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
LZS2_k127_6100812_7	649638.Trad_1833	7.947e-44	167.0	COG1802@1|root,COG1802@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
LZS2_k127_6100812_2	1906.SFRA_26855	7.351e-173	586.0	COG0642@1|root,COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria,2ICPA@201174|Actinobacteria	201174|Actinobacteria	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Peripla_BP_3,Response_reg
LZS2_k127_6100812_3	383372.Rcas_2455	4.673e-162	522.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS2_k127_6100812_0	383372.Rcas_2454	5.531e-244	771.0	COG0747@1|root,COG0747@2|Bacteria,2G84E@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_6100812_5	383372.Rcas_2453	1.386e-149	479.0	COG0601@1|root,COG0601@2|Bacteria,2G7WN@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_6100812_4	383372.Rcas_2452	3.188e-157	504.0	COG1173@1|root,COG1173@2|Bacteria,2G7U9@200795|Chloroflexi,377XX@32061|Chloroflexia	32061|Chloroflexia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_6100812_6	383372.Rcas_2451	1.687e-48	177.0	COG0444@1|root,COG0444@2|Bacteria,2G893@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS2_k127_6104560_2	525904.Tter_2165	6.356e-23	100.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
LZS2_k127_6104560_1	1121324.CLIT_2c01420	3.713e-28	116.0	COG0389@1|root,COG0389@2|Bacteria,1VEU0@1239|Firmicutes,24RTW@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cdd1
LZS2_k127_6104560_0	383372.Rcas_4419	1.374e-131	432.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,3751P@32061|Chloroflexia	32061|Chloroflexia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS2_k127_6109464_2	1499967.BAYZ01000048_gene2717	8.715e-89	296.0	COG0169@1|root,COG0169@2|Bacteria,2NPR3@2323|unclassified Bacteria	2|Bacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
LZS2_k127_6109464_0	926550.CLDAP_27180	0.0	1654.0	COG4284@1|root,COG4284@2|Bacteria	2|Bacteria	G	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
LZS2_k127_6109464_1	926550.CLDAP_34490	1.387e-122	399.0	COG1210@1|root,COG1210@2|Bacteria,2G6XV@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS2_k127_6109464_4	383372.Rcas_0284	2.116e-78	284.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi,374XW@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
LZS2_k127_6109464_3	1521187.JPIM01000055_gene3648	1.464e-79	272.0	COG0578@1|root,COG0578@2|Bacteria,2G63S@200795|Chloroflexi,3750F@32061|Chloroflexia	32061|Chloroflexia	C	BFD domain protein 2Fe-2S -binding domain protein	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
LZS2_k127_61133_2	1396141.BATP01000007_gene5691	1.299e-11	79.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg,DUF4440,Erythro_esteras
LZS2_k127_61133_0	1396141.BATP01000057_gene3053	3.586e-146	499.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
LZS2_k127_61133_1	553973.CLOHYLEM_06986	1.427e-30	124.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,220M1@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
LZS2_k127_61133_3	273068.TTE1659	1.291e-09	61.0	2E4Y1@1|root,32ZRZ@2|Bacteria,1VGPN@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6113527_1	555079.Toce_2001	3.521e-204	642.0	COG2403@1|root,COG2403@2|Bacteria,1TPZD@1239|Firmicutes,24E2D@186801|Clostridia,42HSE@68295|Thermoanaerobacterales	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
LZS2_k127_6113527_3	926569.ANT_21970	3.061e-45	177.0	COG1073@1|root,COG1073@2|Bacteria,2G73I@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_6113527_2	926550.CLDAP_13620	1.056e-160	512.0	COG1063@1|root,COG1063@2|Bacteria,2G7MF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
LZS2_k127_6113527_0	926550.CLDAP_34660	8.003e-272	847.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
LZS2_k127_6123606_3	1125700.HMPREF9195_01842	3.92e-07	59.0	COG1286@1|root,COG1286@2|Bacteria,2J7ZK@203691|Spirochaetes	203691|Spirochaetes	S	CvpA family	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
LZS2_k127_6123606_0	926550.CLDAP_05500	4.677e-216	697.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
LZS2_k127_6123606_1	926550.CLDAP_14890	3.762e-79	274.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
LZS2_k127_6123606_2	1382306.JNIM01000001_gene1173	6.114e-23	105.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
LZS2_k127_6129611_0	1499967.BAYZ01000029_gene1217	1.307e-84	296.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GAF_3,Response_reg,SpoIIE
LZS2_k127_6129611_2	1499967.BAYZ01000139_gene144	2.653e-28	118.0	COG2199@1|root,COG3706@2|Bacteria,2NR9S@2323|unclassified Bacteria	2|Bacteria	T	Domain of unknown function (DUF4388)	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheX,HATPase_c,HisKA,Response_reg
LZS2_k127_6129611_3	2423.NA23_0205980	1.333e-09	64.0	COG1366@1|root,COG1366@2|Bacteria,2GDAN@200918|Thermotogae	200918|Thermotogae	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
LZS2_k127_6129611_1	266117.Rxyl_2664	2.55e-29	122.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	GAF_2,HATPase_c_2,SpoIIE
LZS2_k127_6130053_3	926569.ANT_19780	8.322e-07	52.0	COG2887@1|root,COG2887@2|Bacteria,2G8SQ@200795|Chloroflexi	200795|Chloroflexi	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
LZS2_k127_6130053_1	926569.ANT_28330	2.017e-168	556.0	COG0608@1|root,COG0608@2|Bacteria,2G7JK@200795|Chloroflexi	200795|Chloroflexi	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
LZS2_k127_6130053_0	1408473.JHXO01000004_gene100	1.514e-170	540.0	COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,2FPNE@200643|Bacteroidia	976|Bacteroidetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS2_k127_6130053_2	525904.Tter_2307	1.253e-94	323.0	COG3004@1|root,COG3004@2|Bacteria,2NNWA@2323|unclassified Bacteria	2|Bacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
LZS2_k127_6227873_7	926569.ANT_10420	6.712e-22	98.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS2_k127_6227873_5	326427.Cagg_1631	9.081e-32	128.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi,375NS@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
LZS2_k127_6227873_3	926569.ANT_22610	2.277e-88	303.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
LZS2_k127_6227873_2	926550.CLDAP_31440	1.807e-92	315.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
LZS2_k127_6227873_6	926550.CLDAP_31430	4.652e-24	110.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS2_k127_6227873_0	525904.Tter_1750	1.548e-274	857.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS2_k127_6227873_1	1280390.CBQR020000005_gene116	1.279e-119	396.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli,26QPQ@186822|Paenibacillaceae	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS2_k127_6227873_4	926550.CLDAP_11360	2.049e-67	240.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
LZS2_k127_6239972_8	1121422.AUMW01000009_gene3341	3.591e-59	209.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,261PP@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM glycyl-radical enzyme activating protein family	csdA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
LZS2_k127_6239972_0	1121422.AUMW01000009_gene3340	0.0	1229.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,2618A@186807|Peptococcaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
LZS2_k127_6239972_4	357808.RoseRS_2519	9.7e-83	286.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi,3762A@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_6239972_6	926569.ANT_13330	4.733e-77	285.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_6239972_14	926550.CLDAP_10530	1.362e-28	134.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_6239972_2	349161.Dred_2781	1.254e-113	374.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24DJF@186801|Clostridia,26573@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS2_k127_6239972_7	1449126.JQKL01000035_gene2174	7.82e-63	245.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,2683T@186813|unclassified Clostridiales	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_6239972_3	926550.CLDAP_16140	3.875e-103	345.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
LZS2_k127_6239972_12	926569.ANT_11850	2.059e-30	123.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
LZS2_k127_6239972_15	1173022.Cri9333_4632	4.932e-13	83.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,3.1.1.61	ko:K02658,ko:K13924	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko02044	-	-	-	CHASE,HATPase_c,HisKA,PAS,Response_reg
LZS2_k127_6239972_1	316274.Haur_1218	1.233e-169	556.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733,ko:K22010	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018,M00839	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	HATPase_c,HisKA,PALP,Response_reg
LZS2_k127_6239972_5	926569.ANT_11780	7.976e-82	305.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_6239972_9	316274.Haur_1217	4.964e-48	196.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_6239972_13	926569.ANT_11810	1.072e-28	134.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
LZS2_k127_6239972_10	1122137.AQXF01000001_gene3001	5.132e-46	190.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PilZ,dCache_1
LZS2_k127_6239972_11	402777.KB235903_gene1310	1.586e-42	173.0	COG2202@1|root,COG2964@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2964@2|Bacteria,COG4191@2|Bacteria,1G07W@1117|Cyanobacteria,1HA1U@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
LZS2_k127_6262911_8	1382356.JQMP01000004_gene167	5.012e-18	92.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi,27XID@189775|Thermomicrobia	189775|Thermomicrobia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_6262911_0	562970.Btus_1445	5.804e-142	462.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF_1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS2_k127_6262911_7	1087481.AGFX01000029_gene1178	8.142e-24	110.0	COG1420@1|root,COG1420@2|Bacteria,1V3FM@1239|Firmicutes,4HHMU@91061|Bacilli,26W25@186822|Paenibacillaceae	91061|Bacilli	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repress,MarR
LZS2_k127_6262911_6	997346.HMPREF9374_0915	1.571e-55	205.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,27BEX@186824|Thermoactinomycetaceae	91061|Bacilli	S	Dihydroxyacetone kinase family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
LZS2_k127_6262911_5	926550.CLDAP_37940	7.883e-56	201.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_6262911_4	66692.ABC2308	1.11e-57	211.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli,1ZCK2@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yitS	-	-	-	-	-	-	-	-	-	-	-	DegV
LZS2_k127_6262911_3	28072.Nos7524_0700	2.127e-63	224.0	COG4405@1|root,COG4405@2|Bacteria,1GE0T@1117|Cyanobacteria	1117|Cyanobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
LZS2_k127_6262911_1	1499967.BAYZ01000018_gene6342	3.89e-72	249.0	COG3506@1|root,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	yjl217W	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
LZS2_k127_6262911_2	1499967.BAYZ01000006_gene5468	1.935e-65	240.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_6263740_0	158189.SpiBuddy_0755	2.841e-287	898.0	COG1501@1|root,COG1501@2|Bacteria,2J722@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
LZS2_k127_6263740_1	926550.CLDAP_36500	3.707e-27	113.0	COG1609@1|root,COG1609@2|Bacteria,2G6CQ@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_6270529_1	272134.KB731325_gene568	1.203e-65	232.0	COG3385@1|root,COG3385@2|Bacteria,1G8HU@1117|Cyanobacteria,1HD8S@1150|Oscillatoriales	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
LZS2_k127_6270529_0	452637.Oter_3063	9.263e-112	367.0	COG3408@1|root,COG3408@2|Bacteria,46U0C@74201|Verrucomicrobia,3K76I@414999|Opitutae	414999|Opitutae	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
LZS2_k127_6280860_2	1301100.HG529358_gene2031	5.158e-34	140.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
LZS2_k127_6280860_0	926569.ANT_08650	2.981e-169	542.0	COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
LZS2_k127_6280860_3	1122921.KB898189_gene724	3.356e-07	53.0	2BR0X@1|root,32JYC@2|Bacteria,1U1R4@1239|Firmicutes,4IB7I@91061|Bacilli,273UA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6280860_1	498761.HM1_3129	1.155e-37	142.0	2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes,24KKM@186801|Clostridia	186801|Clostridia	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6332125_1	292459.STH749	2.572e-59	218.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS2_k127_6332125_0	357808.RoseRS_3344	5.808e-67	236.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
LZS2_k127_6332125_2	717605.Theco_0907	1.587e-25	108.0	COG0454@1|root,COG0456@2|Bacteria,1V37I@1239|Firmicutes,4HGJH@91061|Bacilli,26TQ6@186822|Paenibacillaceae	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_6371301_0	485913.Krac_3283	2.607e-162	531.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
LZS2_k127_6371301_1	1116472.MGMO_126c00390	1.65e-28	117.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 2 family	uidA	GO:0003674,GO:0003824,GO:0004553,GO:0004566,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016054,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0019389,GO:0019391,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
LZS2_k127_6371877_14	1122917.KB899665_gene4161	1.187e-21	99.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,26ZAP@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
LZS2_k127_6371877_0	926550.CLDAP_11170	7.284e-198	628.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS2_k127_6371877_8	765420.OSCT_0418	1.938e-49	185.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi,3773X@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_6371877_11	1201292.DR75_259	5.594e-28	132.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,4AZVU@81852|Enterococcaceae	91061|Bacilli	T	PAS domain	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
LZS2_k127_6371877_7	383372.Rcas_2148	2.242e-50	204.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
LZS2_k127_6371877_5	926550.CLDAP_14080	6.104e-59	212.0	COG0745@1|root,COG0745@2|Bacteria	926550.CLDAP_14080|-	T	phosphorelay signal transduction system	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
LZS2_k127_6371877_19	639030.JHVA01000001_gene528	0.0001483	55.0	COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
LZS2_k127_6371877_12	383372.Rcas_3199	8.128e-24	105.0	COG0745@1|root,COG0745@2|Bacteria,2G9ZW@200795|Chloroflexi,377JC@32061|Chloroflexia	32061|Chloroflexia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_6371877_16	316274.Haur_2684	3.624e-14	77.0	COG2172@1|root,COG2172@2|Bacteria,2GBSX@200795|Chloroflexi,375PM@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
LZS2_k127_6371877_18	675635.Psed_4132	7.036e-07	62.0	COG2203@1|root,COG3835@1|root,COG2203@2|Bacteria,COG3835@2|Bacteria,2I3S0@201174|Actinobacteria,4EF84@85010|Pseudonocardiales	201174|Actinobacteria	T	PFAM GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_30
LZS2_k127_6371877_2	215803.DB30_5082	2.866e-93	317.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42QZV@68525|delta/epsilon subdivisions,2WN5Z@28221|Deltaproteobacteria,2YUTI@29|Myxococcales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB4	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
LZS2_k127_6371877_1	443143.GM18_2208	1.12e-147	497.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria,43T72@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	ATP-binding region, ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
LZS2_k127_6371877_3	357808.RoseRS_0999	3.304e-84	301.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,2G716@200795|Chloroflexi,376VE@32061|Chloroflexia	32061|Chloroflexia	T	PFAM histidine kinase, HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,MCPsignal
LZS2_k127_6371877_10	296591.Bpro_2460	7.312e-34	138.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,4ADEE@80864|Comamonadaceae	28216|Betaproteobacteria	NT	PFAM CheW domain protein	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS2_k127_6371877_4	383372.Rcas_3195	6.654e-77	278.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,2G79T@200795|Chloroflexi,3765U@32061|Chloroflexia	32061|Chloroflexia	NT	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16
LZS2_k127_6371877_13	1379281.AVAG01000068_gene681	3.536e-22	105.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,42T5Y@68525|delta/epsilon subdivisions,2WNT6@28221|Deltaproteobacteria,2MAZR@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS2_k127_6371877_15	517418.Ctha_2358	5.507e-21	97.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
LZS2_k127_6371877_9	765420.OSCT_3148	2.072e-38	154.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_6371877_6	765420.OSCT_0222	6.578e-53	205.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,2GBJN@200795|Chloroflexi,3780Z@32061|Chloroflexia	32061|Chloroflexia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
LZS2_k127_6384806_6	1536769.P40081_10815	2.307e-05	57.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,26QKX@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS2_k127_6384806_3	926569.ANT_19040	1.663e-24	106.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6384806_4	1487953.JMKF01000022_gene2543	1.223e-21	111.0	COG2385@1|root,COG2385@2|Bacteria,1G2FP@1117|Cyanobacteria,1H8UJ@1150|Oscillatoriales	1117|Cyanobacteria	D	PFAM Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
LZS2_k127_6384806_7	877411.JMMA01000002_gene1789	0.0005299	53.0	COG2385@1|root,COG2385@2|Bacteria,1V9H8@1239|Firmicutes,24K70@186801|Clostridia,3WI9P@541000|Ruminococcaceae	186801|Clostridia	D	SpoIID LytB domain protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	CinA,MoCF_biosynth,Sortase,SpoIID
LZS2_k127_6384806_0	926569.ANT_26230	8.405e-116	385.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
LZS2_k127_6384806_5	1454004.AW11_00765	1.528e-10	64.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,1KQ52@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
LZS2_k127_6384806_1	926550.CLDAP_05540	7.408e-60	220.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS2_k127_6384806_2	926550.CLDAP_10880	7.354e-36	145.0	COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi	200795|Chloroflexi	K	Fibronectin-binding A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
LZS2_k127_6385247_1	357808.RoseRS_2273	3.45e-97	332.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_6385247_0	479434.Sthe_2769	5.292e-132	433.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia	189775|Thermomicrobia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_6385247_3	926550.CLDAP_16430	1.251e-70	246.0	COG2949@1|root,COG2949@2|Bacteria,2G6VI@200795|Chloroflexi	200795|Chloroflexi	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
LZS2_k127_6385247_2	1121033.AUCF01000001_gene2030	3.613e-74	255.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2JRZ1@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_638915_4	926550.CLDAP_20130	1.466e-133	436.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS2_k127_638915_1	1267580.AF6_0221	2.75e-198	638.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli,21V85@150247|Anoxybacillus	91061|Bacilli	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS2_k127_638915_23	326427.Cagg_2441	6.919e-06	55.0	COG3103@1|root,COG3103@2|Bacteria,2G7IJ@200795|Chloroflexi,377K8@32061|Chloroflexia	32061|Chloroflexia	T	PFAM SH3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
LZS2_k127_638915_8	316274.Haur_0491	5.536e-51	196.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,376A8@32061|Chloroflexia	2|Bacteria	KT	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3,4.2.3.3	ko:K01734,ko:K07315,ko:K10914	ko00640,ko01120,ko02020,ko02024,ko02025,ko02026,ko05111,map00640,map01120,map02020,map02024,map02025,map02026,map05111	-	R01016	RC00424	ko00000,ko00001,ko01000,ko03000,ko03021	-	-	-	CHASE2,HATPase_c_2,HTH_Crp_2,MGS,Response_reg,SpoIIE,cNMP_binding
LZS2_k127_638915_14	926569.ANT_06610	7.406e-22	100.0	COG0745@1|root,COG0745@2|Bacteria,2G986@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_638915_0	1128421.JAGA01000003_gene3441	9.797e-203	638.0	COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
LZS2_k127_638915_3	109760.SPPG_01853T0	7.843e-162	523.0	COG0165@1|root,KOG1316@2759|Eukaryota,38CSU@33154|Opisthokonta,3NVYH@4751|Fungi	4751|Fungi	E	Argininosuccinate lyase	ARG4	GO:0000050,GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
LZS2_k127_638915_10	1496688.ER33_06310	8.668e-42	166.0	COG0265@1|root,COG0265@2|Bacteria,1GDXK@1117|Cyanobacteria,22TSG@167375|Cyanobium	1117|Cyanobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
LZS2_k127_638915_17	1496688.ER33_06305	2.301e-16	86.0	2EHTN@1|root,33BJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
LZS2_k127_638915_24	984262.SGRA_1649	0.0006768	50.0	COG0457@1|root,COG0457@2|Bacteria,4NG1I@976|Bacteroidetes,1IPQK@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
LZS2_k127_638915_6	357808.RoseRS_2700	5.306e-74	267.0	2EWUK@1|root,33Q65@2|Bacteria,2GAC8@200795|Chloroflexi,3755J@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
LZS2_k127_638915_18	324602.Caur_3188	1.089e-13	84.0	COG1511@1|root,COG1511@2|Bacteria,2GAEF@200795|Chloroflexi,375SE@32061|Chloroflexia	32061|Chloroflexia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_638915_15	929556.Solca_1423	1.824e-20	93.0	2BTNY@1|root,32NVY@2|Bacteria,4NV0G@976|Bacteroidetes,1IUM3@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
LZS2_k127_638915_5	357808.RoseRS_3453	3.896e-109	358.0	COG3828@1|root,COG3828@2|Bacteria,2G61G@200795|Chloroflexi	200795|Chloroflexi	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
LZS2_k127_638915_2	1304880.JAGB01000002_gene2262	2.67e-173	549.0	COG0673@1|root,COG0673@2|Bacteria,1U4A4@1239|Firmicutes,249UF@186801|Clostridia	186801|Clostridia	E	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS2_k127_638915_11	316274.Haur_3174	4.796e-33	137.0	COG0500@1|root,COG2226@2|Bacteria,2GB34@200795|Chloroflexi,3778K@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_638915_12	383372.Rcas_2695	2.03e-31	128.0	COG1833@1|root,COG1833@2|Bacteria,2G7CM@200795|Chloroflexi,377P6@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function DUF123	-	-	-	-	-	-	-	-	-	-	-	-	DUF123
LZS2_k127_638915_19	1121013.P873_01750	2.715e-13	77.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria,1X6YB@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
LZS2_k127_638915_9	452637.Oter_3829	2.944e-49	190.0	COG1524@1|root,COG1524@2|Bacteria,46VXF@74201|Verrucomicrobia,3K93S@414999|Opitutae	414999|Opitutae	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_638915_7	485913.Krac_9221	1.346e-57	216.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi	485913.Krac_9221|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_638915_20	1304880.JAGB01000001_gene701	3.348e-11	75.0	COG1388@1|root,COG1388@2|Bacteria,1UHZC@1239|Firmicutes,25E80@186801|Clostridia	186801|Clostridia	M	Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
LZS2_k127_638915_13	880073.Calab_0584	2.34e-28	121.0	2AN2Z@1|root,31D0J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_638915_22	638302.HMPREF0908_0820	4.449e-06	53.0	2EDCQ@1|root,33791@2|Bacteria,1VHPR@1239|Firmicutes,4H84G@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6397059_12	326427.Cagg_1239	2.237e-07	62.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6397059_4	926550.CLDAP_02300	4.828e-123	421.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi	200795|Chloroflexi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6397059_3	443144.GM21_0452	5.497e-159	530.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1,sCache_2
LZS2_k127_6397059_10	1521187.JPIM01000018_gene424	3.283e-12	79.0	COG2723@1|root,COG2723@2|Bacteria,2GBIH@200795|Chloroflexi,3771Z@32061|Chloroflexia	32061|Chloroflexia	G	6-phospho-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FlaA,Glyco_hydro_42,Glyco_hydro_cc
LZS2_k127_6397059_6	926550.CLDAP_29840	1.815e-30	138.0	COG3023@1|root,COG4423@1|root,COG3023@2|Bacteria,COG4423@2|Bacteria	2|Bacteria	S	positive regulation of growth	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	Amidase_2,PG_binding_1,PSK_trans_fac
LZS2_k127_6397059_5	1499967.BAYZ01000116_gene3138	9.214e-42	164.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
LZS2_k127_6397059_8	926550.CLDAP_34200	6.381e-20	91.0	2E5PY@1|root,330EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6397059_1	383372.Rcas_1884	2.967e-229	720.0	COG1486@1|root,COG1486@2|Bacteria,2G5M6@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
LZS2_k127_6397059_11	1499967.BAYZ01000157_gene589	1.065e-07	54.0	COG1486@1|root,COG1486@2|Bacteria,2NQ9I@2323|unclassified Bacteria	2|Bacteria	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
LZS2_k127_6397059_0	926550.CLDAP_12850	2.889e-231	722.0	COG1486@1|root,COG1486@2|Bacteria,2G5KA@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
LZS2_k127_6397059_7	926569.ANT_08830	3.57e-21	98.0	COG4818@1|root,COG4818@2|Bacteria	2|Bacteria	S	TM2 domain	M1-746	-	-	-	-	-	-	-	-	-	-	-	DUF4870
LZS2_k127_6397059_2	926569.ANT_08840	1.048e-169	537.0	COG4608@1|root,COG4608@2|Bacteria,2G7YH@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS2_k127_6397059_9	388739.RSK20926_09819	3.24e-19	99.0	COG0697@1|root,COG3391@1|root,COG0697@2|Bacteria,COG3391@2|Bacteria,1QYKD@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
LZS2_k127_6420207_3	102125.Xen7305DRAFT_00040270	1.395e-06	51.0	COG3385@1|root,COG3385@2|Bacteria,1G8HU@1117|Cyanobacteria,3VMID@52604|Pleurocapsales	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
LZS2_k127_6420207_0	255470.cbdbA1371	2.895e-229	723.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,34CRC@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
LZS2_k127_6420207_1	926569.ANT_15680	6.017e-70	249.0	COG4974@1|root,COG4974@2|Bacteria,2G94T@200795|Chloroflexi	200795|Chloroflexi	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS2_k127_6420207_2	321327.CYA_2401	3.09e-56	210.0	COG1404@1|root,COG1404@2|Bacteria,1G1G8@1117|Cyanobacteria,1GYXZ@1129|Synechococcus	1117|Cyanobacteria	O	Peptidase, S8A (Subtilisin) family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
LZS2_k127_6425300_1	479434.Sthe_3433	7.354e-37	147.0	2DMIY@1|root,32RWI@2|Bacteria,2G7AX@200795|Chloroflexi	200795|Chloroflexi	S	CRISPR_assoc	-	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
LZS2_k127_6425300_0	479434.Sthe_3432	2.742e-107	355.0	COG1518@1|root,COG1518@2|Bacteria,2G5Z6@200795|Chloroflexi	200795|Chloroflexi	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
LZS2_k127_6425300_2	479434.Sthe_3431	4.593e-28	118.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	cas2	GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0034641,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:1901360	2.7.7.7	ko:K02342,ko:K09951	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03400	-	-	-	Cas_Cas2CT1978,RNase_T
LZS2_k127_6425300_3	411464.DESPIG_00034	0.0001682	46.0	2DMND@1|root,32SNQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6463421_0	759914.BP951000_0086	9.735e-205	656.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2J5ZA@203691|Spirochaetes	203691|Spirochaetes	I	CoA-substrate-specific enzyme activase	yxcA	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
LZS2_k127_6465436_3	1408418.JNJH01000011_gene3690	1.043e-34	138.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2U7KP@28211|Alphaproteobacteria,2JWJ0@204441|Rhodospirillales	204441|Rhodospirillales	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS2_k127_6465436_1	1121127.JAFA01000007_gene5324	7.273e-90	303.0	COG1129@1|root,COG1129@2|Bacteria,1MW4I@1224|Proteobacteria,2WCZX@28216|Betaproteobacteria,1K6US@119060|Burkholderiaceae	28216|Betaproteobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
LZS2_k127_6465436_2	1121382.JQKG01000063_gene3032	2.021e-74	273.0	COG1172@1|root,COG1172@2|Bacteria,1WK1K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	COGs COG1172 Ribose xylose arabinose galactoside ABC-type transport systems permease components	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
LZS2_k127_6465436_0	935948.KE386495_gene1852	1.337e-151	494.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,42FNU@68295|Thermoanaerobacterales	186801|Clostridia	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
LZS2_k127_6484263_0	383372.Rcas_0195	1.495e-26	125.0	COG0457@1|root,COG0457@2|Bacteria,2GB3M@200795|Chloroflexi,377UW@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
LZS2_k127_6485061_4	926550.CLDAP_02320	2.729e-63	227.0	COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_6485061_0	926550.CLDAP_01710	2.069e-150	486.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
LZS2_k127_6485061_5	357808.RoseRS_3530	4.964e-62	223.0	COG1912@1|root,COG1912@2|Bacteria,2G6NI@200795|Chloroflexi,376J1@32061|Chloroflexia	32061|Chloroflexia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
LZS2_k127_6485061_1	96561.Dole_2364	7.831e-90	308.0	COG0530@1|root,COG0530@2|Bacteria,1PMPU@1224|Proteobacteria,43A4H@68525|delta/epsilon subdivisions,2X26D@28221|Deltaproteobacteria,2MM3E@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
LZS2_k127_6485061_2	926569.ANT_12940	2.815e-84	293.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
LZS2_k127_6485061_3	926550.CLDAP_30680	2.225e-74	262.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
LZS2_k127_6511198_4	926550.CLDAP_41100	6.527e-50	180.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
LZS2_k127_6511198_0	926569.ANT_08710	2.101e-136	457.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
LZS2_k127_6511198_1	926550.CLDAP_22030	2.868e-129	426.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_6511198_2	926550.CLDAP_00060	7.177e-100	334.0	COG0265@1|root,COG0265@2|Bacteria,2G6I9@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_6511198_6	926550.CLDAP_35250	1.583e-47	177.0	COG2197@1|root,COG2197@2|Bacteria,2G73R@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
LZS2_k127_6511198_3	880073.Calab_2028	4.358e-99	332.0	COG2084@1|root,COG2084@2|Bacteria,2NP96@2323|unclassified Bacteria	2|Bacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
LZS2_k127_6511198_5	880073.Calab_0097	4.617e-48	187.0	COG4099@1|root,COG4099@2|Bacteria,2NQ8A@2323|unclassified Bacteria	2|Bacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Esterase,Esterase_phd,Peptidase_S9
LZS2_k127_6704098_0	338963.Pcar_2035	3.774e-131	427.0	COG0438@1|root,COG0438@2|Bacteria,1NA28@1224|Proteobacteria,42NZA@68525|delta/epsilon subdivisions,2WK1T@28221|Deltaproteobacteria,43U4C@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Domain of unknown function (DUF3524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3524,Glycos_transf_1
LZS2_k127_6704098_1	395493.BegalDRAFT_0269	2.171e-112	373.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,1T4BG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,Response_reg
LZS2_k127_6704098_2	525904.Tter_0795	6.006e-75	261.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS2_k127_6704098_3	1123288.SOV_2c07050	1.127e-61	221.0	COG1040@1|root,COG1040@2|Bacteria,1VF3F@1239|Firmicutes	1239|Firmicutes	S	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zinc_ribbon_2
LZS2_k127_6719648_9	1192034.CAP_7816	0.0002387	52.0	29X8Q@1|root,30IY3@2|Bacteria,1QZTR@1224|Proteobacteria,43CNP@68525|delta/epsilon subdivisions,2X7VZ@28221|Deltaproteobacteria,2YYEQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6719648_6	653733.Selin_0487	6.249e-18	98.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
LZS2_k127_6719648_1	926569.ANT_08850	3.474e-148	478.0	COG1173@1|root,COG1173@2|Bacteria,2G7U9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_6719648_3	926550.CLDAP_12890	6.152e-124	405.0	COG0601@1|root,COG0601@2|Bacteria,2G7WN@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_6719648_0	926569.ANT_08870	7.827e-245	776.0	COG0747@1|root,COG0747@2|Bacteria,2G84E@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_6719648_2	926569.ANT_08880	2.191e-146	470.0	COG0444@1|root,COG0444@2|Bacteria,2G7RV@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS2_k127_6719648_5	1382356.JQMP01000001_gene939	3.313e-65	235.0	COG1609@1|root,COG1609@2|Bacteria,2G6CQ@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_6719648_4	760568.Desku_1636	7.159e-71	253.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,261SM@186807|Peptococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02525,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
LZS2_k127_6719648_8	316274.Haur_3663	1.623e-07	53.0	COG0235@1|root,COG0235@2|Bacteria,2G63H@200795|Chloroflexi	200795|Chloroflexi	G	Class II Aldolase and Adducin N-terminal domain	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
LZS2_k127_6719648_7	697329.Rumal_2824	6.239e-14	71.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3WH0C@541000|Ruminococcaceae	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
LZS2_k127_6776384_2	927658.AJUM01000017_gene3133	3.959e-104	345.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,4NIHT@976|Bacteroidetes,2FP3D@200643|Bacteroidia,3XIPS@558415|Marinilabiliaceae	976|Bacteroidetes	F	Phosphoribulokinase / Uridine kinase family	udk2	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
LZS2_k127_6776384_0	562970.Btus_1022	2.182e-244	767.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli,2798V@186823|Alicyclobacillaceae	91061|Bacilli	EG	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	M00019,M00570,M00582	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ILVD_EDD
LZS2_k127_6776384_4	565033.GACE_0682	9.749e-85	288.0	COG0730@1|root,arCOG09610@2157|Archaea	2157|Archaea	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_6776384_3	998674.ATTE01000001_gene1020	2.251e-91	308.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RNQR@1236|Gammaproteobacteria,462NN@72273|Thiotrichales	72273|Thiotrichales	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_6776384_6	1304885.AUEY01000045_gene249	1.563e-18	89.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,2MJNP@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_5,PAS_8
LZS2_k127_6776384_1	1499967.BAYZ01000100_gene3441	2.46e-110	363.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	ycjP	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_6778742_5	404589.Anae109_3641	2.454e-08	66.0	2E3NC@1|root,32YKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6778742_4	439235.Dalk_5084	1.029e-12	81.0	COG2041@1|root,COG2041@2|Bacteria,1NS6T@1224|Proteobacteria,42YA7@68525|delta/epsilon subdivisions,2WTM5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6778742_6	1201290.M902_3060	0.0001992	49.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,43143@68525|delta/epsilon subdivisions,2MTSP@213481|Bdellovibrionales,2WX54@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_6778742_0	1121481.AUAS01000006_gene877	1.309e-85	301.0	COG1520@1|root,COG2931@1|root,COG5184@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,COG5184@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
LZS2_k127_6778742_2	765420.OSCT_3000	1.983e-57	213.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
LZS2_k127_6778742_1	1049564.TevJSym_ar00350	2.913e-68	258.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,1RQ6X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6778742_3	1499967.BAYZ01000090_gene4936	3.284e-14	86.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_6792202_1	118168.MC7420_3526	3.895e-109	365.0	COG2208@1|root,COG4753@1|root,COG2208@2|Bacteria,COG4753@2|Bacteria,1G160@1117|Cyanobacteria,1HF5Z@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
LZS2_k127_6792202_0	1499967.BAYZ01000105_gene3479	4.091e-224	713.0	COG0745@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,2NS5N@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
LZS2_k127_6804708_3	1089550.ATTH01000001_gene1368	8.81e-15	77.0	COG3270@1|root,COG3270@2|Bacteria	2|Bacteria	J	rRNA methyltransferase activity	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.178	ko:K11392	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
LZS2_k127_6804708_0	926550.CLDAP_22920	0.0	1361.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS2_k127_6804708_1	1121929.KB898665_gene2707	2.222e-221	701.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HCT0@91061|Bacilli,47023@74385|Gracilibacillus	91061|Bacilli	G	Glycosyl hydrolases family 43	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
LZS2_k127_6804708_2	479434.Sthe_1572	5.089e-42	155.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi,27XK9@189775|Thermomicrobia	189775|Thermomicrobia	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
LZS2_k127_6806279_4	926569.ANT_05790	3.542e-41	154.0	COG1529@1|root,COG1529@2|Bacteria,2G7M5@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS2_k127_6806279_3	926569.ANT_05780	3.367e-75	255.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
LZS2_k127_6806279_2	926569.ANT_05770	3.841e-131	424.0	COG1319@1|root,COG1319@2|Bacteria,2G8QI@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS2_k127_6806279_1	158189.SpiBuddy_2605	7.12e-151	481.0	COG1878@1|root,COG1878@2|Bacteria,2JA18@203691|Spirochaetes	203691|Spirochaetes	I	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
LZS2_k127_6806279_0	1293054.HSACCH_00207	5.867e-164	524.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia	186801|Clostridia	C	CoA-transferase family III	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
LZS2_k127_6806279_5	926569.ANT_05660	5.573e-29	119.0	COG0074@1|root,COG0074@2|Bacteria,2G7NQ@200795|Chloroflexi	200795|Chloroflexi	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
LZS2_k127_6812374_0	1499967.BAYZ01000041_gene2393	4.297e-106	364.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HD_5,HisKA,PAS_4,Response_reg
LZS2_k127_6812374_1	485916.Dtox_3785	1.871e-103	345.0	COG1352@1|root,COG1352@2|Bacteria,1TRTF@1239|Firmicutes,24D04@186801|Clostridia,261HW@186807|Peptococcaceae	186801|Clostridia	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
LZS2_k127_6812374_4	485916.Dtox_3784	1.779e-58	208.0	COG2201@1|root,COG2201@2|Bacteria,1VUR7@1239|Firmicutes,2505U@186801|Clostridia,2650Y@186807|Peptococcaceae	186801|Clostridia	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
LZS2_k127_6812374_6	357808.RoseRS_0205	5.119e-27	115.0	COG0784@1|root,COG0784@2|Bacteria,2GB7B@200795|Chloroflexi,377HM@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
LZS2_k127_6812374_3	316274.Haur_4404	4.678e-68	249.0	COG0642@1|root,COG2205@2|Bacteria,2G84W@200795|Chloroflexi,3775F@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS2_k127_6812374_5	485913.Krac_0962	2.525e-37	151.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
LZS2_k127_6815167_8	1247726.MIM_c03750	0.0005298	45.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,2VM56@28216|Betaproteobacteria,3T2SC@506|Alcaligenaceae	28216|Betaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	eamA	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
LZS2_k127_6815167_1	926550.CLDAP_40000	3.871e-88	295.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
LZS2_k127_6815167_6	706434.HMPREF9429_01282	6.714e-11	64.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
LZS2_k127_6815167_3	690850.Desaf_2821	5.247e-33	132.0	COG0726@1|root,COG0726@2|Bacteria,1RH3I@1224|Proteobacteria,42T75@68525|delta/epsilon subdivisions,2WPC1@28221|Deltaproteobacteria,2MEZ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Archaea-specific editing domain of threonyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-Thr_ED
LZS2_k127_6815167_0	926550.CLDAP_18930	2.06e-193	612.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS2_k127_6815167_7	1463885.KL578429_gene9763	2.9e-06	55.0	COG3832@1|root,COG3832@2|Bacteria,2IHQS@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
LZS2_k127_6815167_5	1379698.RBG1_1C00001G1207	2.423e-15	90.0	COG1807@1|root,COG3063@1|root,COG1807@2|Bacteria,COG3063@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_16,TPR_8
LZS2_k127_6815167_2	880073.Calab_3497	4.242e-75	257.0	COG0225@1|root,COG0225@2|Bacteria,2NPBE@2323|unclassified Bacteria	2|Bacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
LZS2_k127_6815167_4	485913.Krac_9745	3.478e-19	89.0	COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS2_k127_6815578_0	383372.Rcas_0577	2.262e-67	252.0	COG0515@1|root,COG0515@2|Bacteria	383372.Rcas_0577|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
LZS2_k127_6815578_1	158190.SpiGrapes_1791	1.176e-34	139.0	COG1102@1|root,COG1102@2|Bacteria,2J5C1@203691|Spirochaetes	203691|Spirochaetes	F	Phospholipid-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
LZS2_k127_6820140_5	399550.Smar_0449	9.69e-44	163.0	COG1042@1|root,arCOG01340@2157|Archaea,2XPR9@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	CoA_binding_2,Succ_CoA_lig
LZS2_k127_6820140_1	497965.Cyan7822_3550	4.837e-286	890.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
LZS2_k127_6820140_3	880073.Calab_1764	8.307e-152	515.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_6820140_2	880073.Calab_1764	3.633e-152	510.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_6820140_4	1121289.JHVL01000009_gene1417	6.946e-85	306.0	COG2984@1|root,COG4191@1|root,COG2984@2|Bacteria,COG4191@2|Bacteria,1UMAC@1239|Firmicutes,25GDF@186801|Clostridia	186801|Clostridia	T	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6820140_0	177437.HRM2_28720	0.0	1103.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2MHMH@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1,6.2.1.17	ko:K01895,ko:K01908	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS2_k127_6820140_6	1161902.HMPREF0378_1513	6.385e-18	90.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WCU7@538999|Clostridiales incertae sedis	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_6838483_0	926550.CLDAP_32690	4.935e-113	374.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2G7SW@200795|Chloroflexi	200795|Chloroflexi	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
LZS2_k127_6854274_0	926550.CLDAP_28250	3.229e-40	153.0	COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
LZS2_k127_6854274_2	290397.Adeh_2146	0.0003338	46.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,2Z04N@29|Myxococcales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
LZS2_k127_6854274_1	1267534.KB906756_gene352	1.557e-30	124.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
LZS2_k127_6861759_0	926569.ANT_11860	1.935e-88	297.0	COG0647@1|root,COG0647@2|Bacteria,2G6QY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
LZS2_k127_6861759_8	926550.CLDAP_24270	2.962e-19	91.0	COG0438@1|root,COG0438@2|Bacteria,2G713@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
LZS2_k127_6861759_1	357808.RoseRS_4448	2.322e-58	213.0	COG0438@1|root,COG0438@2|Bacteria,2G713@200795|Chloroflexi,37525@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
LZS2_k127_6861759_9	941824.TCEL_02370	3.555e-13	75.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,24QQ8@186801|Clostridia,36N1D@31979|Clostridiaceae	186801|Clostridia	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
LZS2_k127_6861759_3	926569.ANT_22490	1.119e-46	181.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
LZS2_k127_6861759_5	926550.CLDAP_29840	6.981e-37	159.0	COG3023@1|root,COG4423@1|root,COG3023@2|Bacteria,COG4423@2|Bacteria	2|Bacteria	S	positive regulation of growth	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	Amidase_2,PG_binding_1,PSK_trans_fac
LZS2_k127_6861759_7	1480694.DC28_12675	4.013e-23	99.0	COG3478@1|root,COG3478@2|Bacteria,2JB4S@203691|Spirochaetes	203691|Spirochaetes	S	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)	-	-	-	ko:K07069	-	-	-	-	ko00000	-	-	-	zinc_ribbon_13
LZS2_k127_6861759_4	326427.Cagg_0218	9.231e-40	164.0	COG0823@1|root,COG0823@2|Bacteria,2G8T8@200795|Chloroflexi,377EP@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS2_k127_6861759_2	926550.CLDAP_04440	8.345e-57	205.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi	200795|Chloroflexi	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
LZS2_k127_6861759_6	926550.CLDAP_04490	8.854e-29	127.0	COG0823@1|root,COG3103@1|root,COG0823@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	NLPC_P60,Rick_17kDa_Anti,SH3_3
LZS2_k127_6866983_2	926550.CLDAP_26570	2.849e-93	323.0	COG0845@1|root,COG0845@2|Bacteria,2G8Q8@200795|Chloroflexi	200795|Chloroflexi	M	secretion protein HlyD family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
LZS2_k127_6866983_0	926550.CLDAP_26560	6.42e-286	908.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
LZS2_k127_6866983_1	357808.RoseRS_0179	1.234e-110	368.0	COG1136@1|root,COG2002@1|root,COG1136@2|Bacteria,COG2002@2|Bacteria,2G5S3@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS2_k127_6866983_3	926550.CLDAP_26540	1.916e-65	229.0	COG1136@1|root,COG1136@2|Bacteria,2G6FP@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_6874406_0	926550.CLDAP_32460	2.712e-86	315.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_6874406_1	926550.CLDAP_32470	5.696e-68	258.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_6876759_9	926569.ANT_17130	7.131e-69	235.0	COG4213@1|root,COG4213@2|Bacteria,2G6C4@200795|Chloroflexi	200795|Chloroflexi	G	Periplasmic binding protein domain	-	-	-	ko:K10543,ko:K10546	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	Peripla_BP_4
LZS2_k127_6876759_0	926569.ANT_17120	1.477e-244	765.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441,ko:K10545,ko:K10548	ko02010,map02010	M00212,M00215,M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
LZS2_k127_6876759_3	926569.ANT_17110	2.057e-175	557.0	COG4214@1|root,COG4214@2|Bacteria,2G8H9@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10544,ko:K10547	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	BPD_transp_2
LZS2_k127_6876759_4	1128421.JAGA01000003_gene3587	9.865e-133	432.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_6876759_6	1380390.JIAT01000011_gene2452	4.292e-102	344.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria,4CS1Y@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
LZS2_k127_6876759_8	1122939.ATUD01000001_gene318	2.126e-92	310.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4CR9Y@84995|Rubrobacteria	84995|Rubrobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
LZS2_k127_6876759_5	1122939.ATUD01000001_gene317	1.135e-113	380.0	COG4214@1|root,COG4214@2|Bacteria,2GJAH@201174|Actinobacteria,4CS8K@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
LZS2_k127_6876759_1	1128421.JAGA01000003_gene3593	1.553e-216	686.0	COG1129@1|root,COG4585@1|root,COG1129@2|Bacteria,COG4585@2|Bacteria,2NPR8@2323|unclassified Bacteria	2|Bacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	2.1.1.80,3.1.1.61,3.6.3.17	ko:K02056,ko:K13924	ko02020,ko02030,map02020,map02030	M00221,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.2	-	-	ABC_tran,HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,SBP_bac_3
LZS2_k127_6876759_14	316274.Haur_3749	2.893e-12	75.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
LZS2_k127_6876759_12	1499967.BAYZ01000069_gene1839	1.154e-30	136.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
LZS2_k127_6876759_13	926569.ANT_16340	5.968e-18	85.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS2_k127_6876759_11	309801.trd_1939	8.553e-43	171.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi,27XYA@189775|Thermomicrobia	189775|Thermomicrobia	M	SMART Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
LZS2_k127_6876759_7	926569.ANT_16280	5.085e-94	330.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF,GAF_2,HATPase_c,HATPase_c_2,HisKA_2
LZS2_k127_6876759_10	926569.ANT_23120	8.422e-56	207.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
LZS2_k127_6876759_2	1449063.JMLS01000027_gene94	1.501e-205	647.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,4HCUX@91061|Bacilli,26RY2@186822|Paenibacillaceae	91061|Bacilli	G	alpha-N-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
LZS2_k127_6878945_1	326427.Cagg_0598	3.824e-114	377.0	COG1063@1|root,COG1063@2|Bacteria,2G5WZ@200795|Chloroflexi,376KB@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_6878945_3	525904.Tter_1208	6.475e-30	128.0	COG0400@1|root,COG0400@2|Bacteria,2NRU7@2323|unclassified Bacteria	2|Bacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
LZS2_k127_6878945_5	745776.DGo_CA0338	8.31e-13	78.0	COG0500@1|root,COG2226@2|Bacteria,1WKDW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_6878945_2	926550.CLDAP_23250	1.59e-62	224.0	COG0500@1|root,COG2226@2|Bacteria,2G9CY@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_6878945_0	1283300.ATXB01000002_gene2809	2.015e-148	488.0	COG0443@1|root,COG0443@2|Bacteria,1Q5TZ@1224|Proteobacteria,1RZCY@1236|Gammaproteobacteria,1XG6Y@135618|Methylococcales	135618|Methylococcales	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
LZS2_k127_6878945_4	1385935.N836_11570	4.039e-13	78.0	COG0576@1|root,COG0576@2|Bacteria,1G8P5@1117|Cyanobacteria	1117|Cyanobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	-	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS2_k127_6879988_2	1279009.ADICEAN_03583	3.394e-118	388.0	COG3342@1|root,COG3342@2|Bacteria,4NITT@976|Bacteroidetes,47JYE@768503|Cytophagia	976|Bacteroidetes	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
LZS2_k127_6879988_1	316274.Haur_1190	1.927e-206	661.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,37597@32061|Chloroflexia	200795|Chloroflexi	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
LZS2_k127_6879988_0	926550.CLDAP_32730	6.229e-211	664.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
LZS2_k127_690825_4	1330700.JQNC01000003_gene1453	1.097e-09	59.0	COG0147@1|root,COG0147@2|Bacteria,1WI8S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
LZS2_k127_690825_2	1122919.KB905597_gene4259	1.366e-79	286.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS2_k127_690825_1	926550.CLDAP_30910	7.451e-118	398.0	COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
LZS2_k127_690825_0	1449976.KALB_1826	1.692e-144	466.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria,4DXDA@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS2_k127_690825_3	926550.CLDAP_30920	4.816e-71	248.0	COG0134@1|root,COG0134@2|Bacteria,2G6GG@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
LZS2_k127_690893_6	6334.EFV48819	0.0001026	55.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3BBF2@33208|Metazoa,3CS4Z@33213|Bilateria,40BUK@6231|Nematoda	33208|Metazoa	T	Cyclic nucleotide-monophosphate binding domain	PRKAR1A	GO:0000003,GO:0000166,GO:0000226,GO:0000280,GO:0001704,GO:0001707,GO:0001932,GO:0001933,GO:0001934,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003006,GO:0003008,GO:0003014,GO:0003091,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005929,GO:0005952,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006469,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0007010,GO:0007015,GO:0007017,GO:0007049,GO:0007143,GO:0007154,GO:0007162,GO:0007163,GO:0007165,GO:0007267,GO:0007268,GO:0007274,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007369,GO:0007389,GO:0007498,GO:0007507,GO:0007591,GO:0007596,GO:0007599,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007635,GO:0008103,GO:0008150,GO:0008152,GO:0008283,GO:0008285,GO:0008306,GO:0008355,GO:0008603,GO:0009611,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0009994,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0010721,GO:0010927,GO:0010948,GO:0014706,GO:0014855,GO:0016020,GO:0016043,GO:0016310,GO:0016325,GO:0017076,GO:0019207,GO:0019210,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0019932,GO:0019933,GO:0019935,GO:0019953,GO:0021700,GO:0022402,GO:0022407,GO:0022408,GO:0022412,GO:0022414,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030029,GO:0030036,GO:0030104,GO:0030154,GO:0030155,GO:0030234,GO:0030239,GO:0030291,GO:0030551,GO:0030552,GO:0030554,GO:0030951,GO:0030952,GO:0031032,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031399,GO:0031400,GO:0031401,GO:0031588,GO:0031594,GO:0031625,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032870,GO:0032878,GO:0032944,GO:0032945,GO:0032989,GO:0032991,GO:0033002,GO:0033043,GO:0033673,GO:0033674,GO:0033762,GO:0034199,GO:0034236,GO:0035265,GO:0035556,GO:0036094,GO:0036211,GO:0040007,GO:0040020,GO:0042048,GO:0042060,GO:0042127,GO:0042129,GO:0042130,GO:0042221,GO:0042303,GO:0042325,GO:0042326,GO:0042327,GO:0042493,GO:0042592,GO:0042692,GO:0042802,GO:0042995,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043412,GO:0043434,GO:0043549,GO:0043900,GO:0043901,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044425,GO:0044441,GO:0044444,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044853,GO:0045121,GO:0045202,GO:0045214,GO:0045471,GO:0045595,GO:0045596,GO:0045786,GO:0045835,GO:0045859,GO:0045860,GO:0045936,GO:0045937,GO:0046006,GO:0046007,GO:0046677,GO:0048285,GO:0048332,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048599,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0048871,GO:0048878,GO:0050670,GO:0050672,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050817,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050877,GO:0050878,GO:0050890,GO:0050891,GO:0050896,GO:0051018,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051249,GO:0051250,GO:0051252,GO:0051321,GO:0051338,GO:0051347,GO:0051348,GO:0051445,GO:0051447,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0055001,GO:0055002,GO:0055017,GO:0060038,GO:0060255,GO:0060259,GO:0060281,GO:0060283,GO:0060284,GO:0060419,GO:0060537,GO:0061061,GO:0061695,GO:0065007,GO:0065008,GO:0065009,GO:0070663,GO:0070664,GO:0070887,GO:0070925,GO:0071310,GO:0071375,GO:0071377,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071900,GO:0071901,GO:0071944,GO:0072359,GO:0072375,GO:0080090,GO:0090036,GO:0090038,GO:0097159,GO:0097305,GO:0097367,GO:0097435,GO:0097546,GO:0098589,GO:0098590,GO:0098772,GO:0098805,GO:0098857,GO:0098916,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0140013,GO:1900193,GO:1900194,GO:1901265,GO:1901363,GO:1901564,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902494,GO:1902531,GO:1902532,GO:1902911,GO:1903037,GO:1903038,GO:1903046,GO:1903429,GO:1903430,GO:1903506,GO:1903538,GO:1905879,GO:1905880,GO:1990234,GO:2000112,GO:2000114,GO:2000241,GO:2000242,GO:2000253,GO:2000479,GO:2000480,GO:2001141	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
LZS2_k127_690893_5	1128421.JAGA01000002_gene171	1.747e-25	123.0	COG3428@1|root,COG3428@2|Bacteria,2NS34@2323|unclassified Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	PASTA,bPH_2
LZS2_k127_690893_4	926569.ANT_11900	1.316e-36	152.0	COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi	200795|Chloroflexi	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
LZS2_k127_690893_0	926550.CLDAP_14740	4.346e-80	275.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
LZS2_k127_690893_2	383372.Rcas_0713	5.643e-44	166.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,375TA@32061|Chloroflexia	32061|Chloroflexia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
LZS2_k127_690893_1	926569.ANT_31660	5.39e-47	177.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
LZS2_k127_690893_3	1382306.JNIM01000001_gene1264	2.711e-39	153.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi	200795|Chloroflexi	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
LZS2_k127_6910488_1	765420.OSCT_1472	3.471e-118	401.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,376RY@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_6910488_0	243164.DET0573	1.298e-122	415.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
LZS2_k127_6910488_2	643648.Slip_0519	3.786e-30	137.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1,HHH_3
LZS2_k127_6930264_0	309801.trd_0655	9.085e-196	614.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,27Y0U@189775|Thermomicrobia	189775|Thermomicrobia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
LZS2_k127_6930264_1	926550.CLDAP_34840	4.978e-78	268.0	COG1349@1|root,COG1349@2|Bacteria,2G8SX@200795|Chloroflexi	200795|Chloroflexi	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
LZS2_k127_6930264_2	1303518.CCALI_02168	1.062e-57	204.0	COG3347@1|root,COG3347@2|Bacteria	2|Bacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
LZS2_k127_6934122_12	621372.ACIH01000143_gene197	9.774e-08	59.0	COG0760@1|root,COG0760@2|Bacteria,1UZZM@1239|Firmicutes,4HE14@91061|Bacilli,26RHI@186822|Paenibacillaceae	91061|Bacilli	O	peptidyl-prolyl isomerase	yacD	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS2_k127_6934122_3	269797.Mbar_A1244	2.803e-179	573.0	COG0520@1|root,arCOG00065@2157|Archaea	2157|Archaea	E	COG0520 Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS2_k127_6934122_10	1089546.AQUI01000002_gene633	1.854e-15	84.0	COG0454@1|root,COG0454@2|Bacteria,2I5JT@201174|Actinobacteria,409JB@622450|Actinopolysporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_6934122_9	1122176.KB903541_gene263	2.577e-25	109.0	COG0296@1|root,COG0296@2|Bacteria,4NSTP@976|Bacteroidetes,1IZE8@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
LZS2_k127_6934122_0	518766.Rmar_1063	1.384e-228	726.0	COG0145@1|root,COG0145@2|Bacteria,4NFBV@976|Bacteroidetes,1FJQ5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
LZS2_k127_6934122_1	518766.Rmar_1062	1.72e-205	653.0	COG0146@1|root,COG0146@2|Bacteria,4PM5E@976|Bacteroidetes,1FJR8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
LZS2_k127_6934122_6	926569.ANT_04770	3.227e-66	257.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
LZS2_k127_6934122_11	926569.ANT_02090	5.676e-15	83.0	29Z2W@1|root,30M0E@2|Bacteria,2G9IN@200795|Chloroflexi	200795|Chloroflexi	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
LZS2_k127_6934122_7	883.DvMF_2543	2.883e-35	139.0	COG0745@1|root,COG0745@2|Bacteria,1PDU9@1224|Proteobacteria,43EXZ@68525|delta/epsilon subdivisions,2X2IY@28221|Deltaproteobacteria,2MD8C@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_6934122_5	926550.CLDAP_37690	1.675e-77	262.0	COG1898@1|root,COG1898@2|Bacteria,2G7AS@200795|Chloroflexi	200795|Chloroflexi	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
LZS2_k127_6934122_2	926550.CLDAP_23750	7.699e-190	605.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
LZS2_k127_6934122_8	1122223.KB890701_gene2198	2.412e-30	130.0	COG0637@1|root,COG0637@2|Bacteria,1WNGW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_6934122_4	32057.KB217478_gene7635	2.771e-80	276.0	COG4719@1|root,COG4932@1|root,COG4719@2|Bacteria,COG4932@2|Bacteria,1GQ4A@1117|Cyanobacteria,1HMAE@1161|Nostocales	1117|Cyanobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6956000_3	316274.Haur_4899	8.488e-16	87.0	COG0457@1|root,COG0457@2|Bacteria	316274.Haur_4899|-	S	peptidyl-tyrosine sulfation	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	-
LZS2_k127_6956000_1	247490.KSU1_C0864	2.374e-63	239.0	COG0457@1|root,COG0457@2|Bacteria,2IWZ3@203682|Planctomycetes	203682|Planctomycetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
LZS2_k127_6956000_2	1379698.RBG1_1C00001G1772	1.55e-32	137.0	COG0457@1|root,COG0457@2|Bacteria,2NQ3H@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
LZS2_k127_6956000_0	335543.Sfum_3112	1.149e-80	275.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MSIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_6965289_2	926569.ANT_15440	1.069e-132	444.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi	200795|Chloroflexi	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
LZS2_k127_6965289_11	1147.D082_13220	1.003e-16	88.0	2CFCI@1|root,32S1P@2|Bacteria,1G4ST@1117|Cyanobacteria,1H6IW@1142|Synechocystis	1117|Cyanobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
LZS2_k127_6965289_9	525904.Tter_0583	3.634e-28	124.0	2AZDP@1|root,31RMA@2|Bacteria,2NRKB@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
LZS2_k127_6965289_12	1123502.AQXD01000005_gene1690	4.465e-16	81.0	COG0107@1|root,COG0139@1|root,COG0107@2|Bacteria,COG0139@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,1X39D@135614|Xanthomonadales	135614|Xanthomonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS2_k127_6965289_0	926550.CLDAP_33860	7.808e-173	551.0	COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi	200795|Chloroflexi	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
LZS2_k127_6965289_6	926550.CLDAP_33900	3.732e-63	226.0	COG0106@1|root,COG0494@1|root,COG0106@2|Bacteria,COG0494@2|Bacteria,2G6EC@200795|Chloroflexi	200795|Chloroflexi	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS2_k127_6965289_5	357808.RoseRS_1120	4.755e-71	246.0	COG0131@1|root,COG0131@2|Bacteria,2G6JA@200795|Chloroflexi,375HN@32061|Chloroflexia	32061|Chloroflexia	E	PFAM imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
LZS2_k127_6965289_10	1227484.C471_11811	2.576e-20	103.0	COG0546@1|root,arCOG04692@2157|Archaea,2XUI7@28890|Euryarchaeota,23SAI@183963|Halobacteria	183963|Halobacteria	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Hydrolase
LZS2_k127_6965289_3	4530.OS02T0709200-01	1.376e-126	416.0	COG0079@1|root,KOG0633@2759|Eukaryota,37KF6@33090|Viridiplantae,3GBQN@35493|Streptophyta,3KRTE@4447|Liliopsida,3I3BA@38820|Poales	35493|Streptophyta	E	Aminotransferase class I and II	-	GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_6965289_13	298654.FraEuI1c_5570	3.997e-08	59.0	COG0454@1|root,COG0456@2|Bacteria,2IRBV@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_6965289_1	1128421.JAGA01000001_gene2397	1.276e-151	492.0	COG0141@1|root,COG0141@2|Bacteria,2NNTS@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
LZS2_k127_6965289_4	242159.ABO94096	7.813e-112	371.0	COG0040@1|root,KOG2831@2759|Eukaryota,37SEA@33090|Viridiplantae,34IBC@3041|Chlorophyta	3041|Chlorophyta	E	ATP phosphoribosyl transferase	-	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
LZS2_k127_6965289_7	858215.Thexy_1884	5.012e-53	191.0	COG1943@1|root,COG1943@2|Bacteria,1V28M@1239|Firmicutes,24G86@186801|Clostridia,42IRE@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM Transposase IS200-like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS2_k127_6965289_8	316274.Haur_2048	2.97e-37	145.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi,376XZ@32061|Chloroflexia	32061|Chloroflexia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS2_k127_6969693_10	1295642.H839_02601	3.825e-48	189.0	COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1WFIP@129337|Geobacillus	91061|Bacilli	O	CAAX prenyl protease N-terminal, five membrane helices	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
LZS2_k127_6969693_11	926550.CLDAP_08190	9.142e-35	138.0	COG2606@1|root,COG2606@2|Bacteria,2G9C3@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
LZS2_k127_6969693_6	383372.Rcas_1288	1.762e-75	268.0	COG0438@1|root,COG0438@2|Bacteria,2G6AR@200795|Chloroflexi,376SQ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_6969693_4	316274.Haur_4741	1.455e-83	287.0	COG1216@1|root,COG1216@2|Bacteria,2G6JZ@200795|Chloroflexi,374VY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_6969693_3	926569.ANT_14700	6.949e-85	291.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS2_k127_6969693_5	555088.DealDRAFT_2567	1.267e-78	273.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,42JSV@68298|Syntrophomonadaceae	186801|Clostridia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
LZS2_k127_6969693_12	32057.KB217478_gene3470	5.617e-34	152.0	COG0457@1|root,COG1672@1|root,COG4928@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG4928@2|Bacteria,1G1HK@1117|Cyanobacteria,1HMEZ@1161|Nostocales	1117|Cyanobacteria	S	PFAM KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
LZS2_k127_6969693_14	926550.CLDAP_10530	1.678e-29	137.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_6969693_15	118168.MC7420_4505	9.415e-15	88.0	COG1672@1|root,COG1672@2|Bacteria,1G5BY@1117|Cyanobacteria,1HDNJ@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Archaeal ATPase	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_22,AAA_35
LZS2_k127_6969693_8	330214.NIDE1491	4.566e-64	230.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
LZS2_k127_6969693_7	56780.SYN_01953	9.475e-74	253.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_6969693_13	926550.CLDAP_06590	6.907e-34	132.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS2_k127_6969693_1	926550.CLDAP_06600	6.121e-240	752.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS2_k127_6969693_17	1238184.CM001792_gene2287	1.663e-05	51.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli,23KVT@182709|Oceanobacillus	91061|Bacilli	S	YtxH-like protein	ytxH	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS2_k127_6969693_9	290315.Clim_1144	7.567e-63	220.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
LZS2_k127_6969693_0	1499967.BAYZ01000036_gene2418	0.0	1237.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_6969693_2	1121396.KB893077_gene739	8.783e-165	523.0	COG0438@1|root,COG0662@1|root,COG0438@2|Bacteria,COG0662@2|Bacteria,1MWSZ@1224|Proteobacteria,42NYZ@68525|delta/epsilon subdivisions,2WK9U@28221|Deltaproteobacteria,2MMTM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
LZS2_k127_6969693_16	1121396.KB893077_gene741	1.574e-13	75.0	COG2152@1|root,COG2152@2|Bacteria,1MX8M@1224|Proteobacteria,42YYU@68525|delta/epsilon subdivisions,2WU8G@28221|Deltaproteobacteria,2MN6U@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Pfam:DUF377	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
LZS2_k127_6972977_1	926550.CLDAP_30400	1.994e-69	249.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
LZS2_k127_6972977_0	1123322.KB904709_gene97	1.377e-98	328.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
LZS2_k127_6972977_2	305900.GV64_16610	6.341e-40	152.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S7F3@1236|Gammaproteobacteria,1XJZB@135619|Oceanospirillales	135619|Oceanospirillales	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
LZS2_k127_6977537_7	530564.Psta_3234	3.272e-19	91.0	COG2931@1|root,COG2931@2|Bacteria,2IZWN@203682|Planctomycetes	203682|Planctomycetes	Q	HemY domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6977537_1	357808.RoseRS_1134	1.606e-137	453.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G67F@200795|Chloroflexi,3769D@32061|Chloroflexia	32061|Chloroflexia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
LZS2_k127_6977537_4	596151.DesfrDRAFT_2592	1.01e-68	242.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2X5IA@28221|Deltaproteobacteria,2MGRF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
LZS2_k127_6977537_5	926569.ANT_15770	3.55e-56	203.0	COG0279@1|root,COG2203@1|root,COG0279@2|Bacteria,COG2203@2|Bacteria,2G6QD@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
LZS2_k127_6977537_6	326427.Cagg_0789	1.245e-50	186.0	COG0241@1|root,COG0241@2|Bacteria,2G6V8@200795|Chloroflexi,375WG@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM histidinol-phosphate phosphatase family protein	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
LZS2_k127_6977537_3	926550.CLDAP_36270	1.394e-81	280.0	COG0110@1|root,COG0110@2|Bacteria,2G6D2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
LZS2_k127_6977537_2	1128421.JAGA01000002_gene761	6.662e-128	421.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	arnC_1	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_6977537_0	926550.CLDAP_36250	4.35e-240	752.0	COG1032@1|root,COG1032@2|Bacteria,2G5SI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_6977537_9	377629.TERTU_2395	8.6e-09	61.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria,2PQJK@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
LZS2_k127_6977537_8	926550.CLDAP_36310	1.066e-09	70.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14,PD40,PKD,VPEP
LZS2_k127_6996018_4	316274.Haur_1055	1.631e-56	204.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi,376D1@32061|Chloroflexia	32061|Chloroflexia	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
LZS2_k127_6996018_1	765420.OSCT_1501	5.179e-93	317.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi,3763Q@32061|Chloroflexia	32061|Chloroflexia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
LZS2_k127_6996018_2	926550.CLDAP_23850	6.084e-81	283.0	COG0079@1|root,COG1492@1|root,COG0079@2|Bacteria,COG1492@2|Bacteria,2G5PU@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
LZS2_k127_6996018_3	926550.CLDAP_24450	1.087e-77	276.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6996018_5	552811.Dehly_0940	1.927e-45	175.0	COG0561@1|root,COG0561@2|Bacteria,2G74S@200795|Chloroflexi,34CR8@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
LZS2_k127_6996018_0	926550.CLDAP_39790	1.112e-222	704.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
LZS2_k127_7010662_2	926550.CLDAP_19990	5.73e-168	534.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_7010662_4	926550.CLDAP_19980	9.412e-126	409.0	COG1175@1|root,COG1175@2|Bacteria,2G6TJ@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_7010662_5	926550.CLDAP_19970	5.354e-120	392.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_7010662_6	1226325.HMPREF1548_00599	1.492e-110	368.0	COG5012@1|root,COG5012@2|Bacteria,1V82H@1239|Firmicutes,25NHT@186801|Clostridia,36SAV@31979|Clostridiaceae	186801|Clostridia	S	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7010662_7	1499967.BAYZ01000108_gene2206	1.252e-108	388.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
LZS2_k127_7010662_10	1304874.JAFY01000002_gene911	0.0004784	54.0	COG2199@1|root,COG3706@2|Bacteria,3TAI8@508458|Synergistetes	508458|Synergistetes	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
LZS2_k127_7010662_8	41431.PCC8801_3753	1.222e-94	346.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1G160@1117|Cyanobacteria,3KFWI@43988|Cyanothece	1117|Cyanobacteria	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
LZS2_k127_7010662_9	697281.Mahau_2080	1.828e-28	127.0	COG0407@1|root,COG0407@2|Bacteria,1V7NA@1239|Firmicutes,24MGR@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
LZS2_k127_7010662_1	663278.Ethha_0756	1.26e-178	586.0	COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,249IJ@186801|Clostridia,3WNST@541000|Ruminococcaceae	186801|Clostridia	G	glycoside hydrolase family 35	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
LZS2_k127_7010662_0	926550.CLDAP_19940	0.0	1182.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
LZS2_k127_7010662_3	545694.TREPR_1522	6.31e-142	462.0	COG0407@1|root,COG0407@2|Bacteria,2J9RK@203691|Spirochaetes	203691|Spirochaetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
LZS2_k127_7024256_0	649638.Trad_2654	6.19e-101	338.0	COG1087@1|root,COG1087@2|Bacteria	2|Bacteria	M	UDP-glucose 4-epimerase activity	galE	-	5.1.3.2,5.1.3.25,5.1.3.6	ko:K01784,ko:K08679,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R01385,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS2_k127_7024256_2	765420.OSCT_0478	6.019e-19	100.0	COG0392@1|root,COG0392@2|Bacteria,2G6NX@200795|Chloroflexi,3765H@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_7024256_1	926550.CLDAP_04470	3.384e-23	102.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7032072_3	1121430.JMLG01000002_gene1099	2.016e-31	132.0	COG4924@1|root,COG4924@2|Bacteria,1V0BQ@1239|Firmicutes,24DRK@186801|Clostridia,2625E@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220,DUF3322
LZS2_k127_7032072_2	255470.cbdbA530	1.7e-52	191.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,34DAC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
LZS2_k127_7032072_1	313628.LNTAR_15902	1.477e-66	232.0	COG0118@1|root,COG0118@2|Bacteria	2|Bacteria	E	glutamine metabolic process	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS2_k127_7032072_0	314230.DSM3645_11012	1.106e-70	248.0	COG0107@1|root,COG0107@2|Bacteria,2IWT4@203682|Planctomycetes	203682|Planctomycetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS2_k127_7040930_3	215803.DB30_0359	0.0001518	52.0	COG3712@1|root,COG3712@2|Bacteria,1PBZ9@1224|Proteobacteria,433U5@68525|delta/epsilon subdivisions,2X3GP@28221|Deltaproteobacteria,2YW0J@29|Myxococcales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,zf-HC2
LZS2_k127_7040930_1	357808.RoseRS_1471	7.662e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_7040930_0	1118054.CAGW01000048_gene1617	5.677e-83	283.0	COG0454@1|root,COG0456@2|Bacteria,1V40T@1239|Firmicutes,4HI2H@91061|Bacilli,26YNM@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_7040930_2	926569.ANT_15080	6.731e-08	66.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
LZS2_k127_7041121_6	1122226.AUHX01000008_gene1483	1.535e-60	215.0	28HP3@1|root,2Z7X8@2|Bacteria,4NPEZ@976|Bacteroidetes,1I268@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7041121_1	1128421.JAGA01000003_gene3536	1.436e-124	413.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_7041121_2	1128421.JAGA01000003_gene3537	7.084e-93	310.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_7041121_5	998674.ATTE01000001_gene3785	6.541e-65	229.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS2_k127_7041121_10	1499967.BAYZ01000078_gene980	3.067e-15	83.0	2DFUU@1|root,2ZT8J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7041121_11	875328.JDM601_2245	1.448e-05	56.0	2CKHU@1|root,32FD5@2|Bacteria,2GU66@201174|Actinobacteria,23B71@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7041121_9	1111479.AXAR01000004_gene2222	8.296e-19	101.0	COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,4HBAR@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 35 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_35
LZS2_k127_7041121_7	68570.DC74_7019	3.442e-52	192.0	COG0637@1|root,COG0637@2|Bacteria,2IQD3@201174|Actinobacteria	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_7041121_4	926550.CLDAP_28550	2.3e-71	264.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
LZS2_k127_7041121_8	28072.Nos7524_1724	1.277e-32	145.0	COG0745@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1G027@1117|Cyanobacteria,1HKPC@1161|Nostocales	1117|Cyanobacteria	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,Trans_reg_C
LZS2_k127_7041121_3	926569.ANT_14300	3.935e-77	265.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_7041121_0	1499967.BAYZ01000161_gene390	1.05e-137	442.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,2NNXD@2323|unclassified Bacteria	2|Bacteria	LV	Eco57I restriction-modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,HSDR_N,N6_Mtase,TaqI_C
LZS2_k127_7061462_1	1235798.C817_04517	1.485e-06	52.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,27WR1@189330|Dorea	186801|Clostridia	S	Survival protein SurE	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
LZS2_k127_7061462_0	926569.ANT_10740	7.128e-51	186.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
LZS2_k127_7063984_2	1382306.JNIM01000001_gene751	1.524e-68	240.0	COG0745@1|root,COG0745@2|Bacteria,2G6H6@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_7063984_1	324602.Caur_3520	6.897e-73	261.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GAF_2,Guanylate_cyc,HAMP,Response_reg,dCache_1
LZS2_k127_7063984_0	1121324.CLIT_2c02290	1.106e-105	355.0	COG0318@1|root,COG0318@2|Bacteria,1UMHB@1239|Firmicutes,25GI8@186801|Clostridia	186801|Clostridia	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
LZS2_k127_7089453_2	1303518.CCALI_01101	5.864e-84	285.0	COG1129@1|root,COG1129@2|Bacteria	2|Bacteria	G	ABC transporter	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
LZS2_k127_7089453_4	667632.KB890164_gene1939	1.093e-70	255.0	COG3437@1|root,COG4585@1|root,COG3437@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2WEET@28216|Betaproteobacteria,1KHSB@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,dCache_1
LZS2_k127_7089453_3	177437.HRM2_24220	1.444e-77	266.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MK6F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_7089453_0	926550.CLDAP_13640	2.959e-235	738.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_7089453_1	1242864.D187_009246	2.962e-184	613.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X83K@28221|Deltaproteobacteria,2YUDP@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
LZS2_k127_7097683_4	545694.TREPR_2694	2.324e-41	171.0	2CFN2@1|root,34AP1@2|Bacteria,2JA1Q@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_7097683_1	1121904.ARBP01000013_gene308	7.498e-96	337.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7097683_2	1128421.JAGA01000002_gene747	1.998e-62	234.0	COG3468@1|root,COG3468@2|Bacteria	2|Bacteria	MU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,BNR_2,Neisseria_TspB,PATR
LZS2_k127_7097683_3	868131.MSWAN_0265	3.004e-51	201.0	COG1807@1|root,arCOG00566@2157|Archaea,2Y4H0@28890|Euryarchaeota	28890|Euryarchaeota	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_7097683_0	926550.CLDAP_27840	1.195e-159	514.0	COG5427@1|root,COG5427@2|Bacteria	2|Bacteria	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7102507_1	316274.Haur_4586	7.062e-121	396.0	COG0667@1|root,COG0667@2|Bacteria,2G7TU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_7102507_4	288000.BBta_7628	1.572e-77	266.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,3JUE4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
LZS2_k127_7102507_2	926569.ANT_07480	3.17e-94	319.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
LZS2_k127_7102507_3	926569.ANT_07490	8.11e-81	278.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
LZS2_k127_7102507_0	926550.CLDAP_04360	6.747e-197	621.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
LZS2_k127_7102507_5	926550.CLDAP_04380	2.193e-15	84.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
LZS2_k127_7109147_11	1116375.VEJY3_08135	0.0005166	53.0	COG3291@1|root,COG3291@2|Bacteria,1QXQ7@1224|Proteobacteria,1T3G4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7109147_7	416591.Tlet_1483	1.509e-35	154.0	COG0613@1|root,COG0613@2|Bacteria,2GCGH@200918|Thermotogae	200918|Thermotogae	L	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7109147_10	1123248.KB893339_gene2701	1.938e-13	83.0	COG4932@1|root,COG5276@1|root,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_3_2,Big_3_5,Big_5,DUF3494
LZS2_k127_7109147_6	926569.ANT_08330	5.496e-39	151.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
LZS2_k127_7109147_0	926550.CLDAP_08740	4.188e-186	599.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
LZS2_k127_7109147_4	926550.CLDAP_08750	5.374e-69	239.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
LZS2_k127_7109147_9	671143.DAMO_2700	3.238e-32	128.0	COG0838@1|root,COG0838@2|Bacteria,2NPTW@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
LZS2_k127_7109147_3	926550.CLDAP_03410	4.114e-84	300.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
LZS2_k127_7109147_2	765420.OSCT_3029	2.378e-84	301.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
LZS2_k127_7109147_1	326427.Cagg_2982	8.794e-167	539.0	COG4962@1|root,COG4962@2|Bacteria,2G7K7@200795|Chloroflexi,3759Z@32061|Chloroflexia	32061|Chloroflexia	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS2_k127_7109147_5	926569.ANT_06880	2.058e-63	243.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
LZS2_k127_7109147_8	326427.Cagg_1904	1.337e-34	137.0	COG0500@1|root,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi,375GC@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_7109316_1	317936.Nos7107_0593	1.16e-89	317.0	28IHG@1|root,2Z8IP@2|Bacteria,1G4GY@1117|Cyanobacteria,1HRM6@1161|Nostocales	1117|Cyanobacteria	S	SPTR Alr4702 protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
LZS2_k127_7109316_2	765420.OSCT_0941	8.307e-74	258.0	COG4279@1|root,COG4279@2|Bacteria,2G7AI@200795|Chloroflexi	200795|Chloroflexi	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
LZS2_k127_7109316_0	272134.KB731324_gene5853	9.381e-153	489.0	COG0553@1|root,COG0553@2|Bacteria,1G0S7@1117|Cyanobacteria,1H7YD@1150|Oscillatoriales	1117|Cyanobacteria	L	SNF2 family N-terminal domain	hepA	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,Intein_splicing,LAGLIDADG_3,SNF2_N
LZS2_k127_7114149_1	1123060.JONP01000029_gene3648	0.0001229	55.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQX3@28211|Alphaproteobacteria,2JZ3J@204441|Rhodospirillales	204441|Rhodospirillales	T	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Pkinase
LZS2_k127_7114149_0	926569.ANT_11830	8.287e-25	121.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
LZS2_k127_7114612_5	1379698.RBG1_1C00001G0015	9.719e-17	91.0	COG0840@1|root,COG4191@1|root,COG0840@2|Bacteria,COG4191@2|Bacteria,2NPGF@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.4.1.12,2.7.13.3,3.1.3.3	ko:K00694,ko:K03406,ko:K07315,ko:K14986	ko00500,ko01100,ko02020,ko02026,ko02030,map00500,map01100,map02020,map02026,map02030	M00524	R02889	RC00005	ko00000,ko00001,ko00002,ko01000,ko01001,ko01003,ko02000,ko02022,ko02035,ko03021	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,HATPase_c,HisKA,NIT,PAS,PAS_4,PAS_9
LZS2_k127_7114612_4	765420.OSCT_3103	4.713e-35	142.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi,375Q8@32061|Chloroflexia	32061|Chloroflexia	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
LZS2_k127_7114612_1	986075.CathTA2_1937	4.972e-136	450.0	COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli	91061|Bacilli	E	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases	dapE	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_7114612_3	485913.Krac_10314	3.863e-64	233.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
LZS2_k127_7114612_2	926550.CLDAP_07940	1.491e-80	287.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
LZS2_k127_7114612_0	518766.Rmar_0699	3.219e-176	560.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1FIMI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Aminotransferase class I and II	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_71379_15	1499967.BAYZ01000139_gene126	1.744e-35	140.0	COG0407@1|root,COG0407@2|Bacteria,2NPXG@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
LZS2_k127_71379_9	926550.CLDAP_14480	4.625e-96	328.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
LZS2_k127_71379_2	926550.CLDAP_19680	6.227e-131	428.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
LZS2_k127_71379_8	926550.CLDAP_19670	2.28e-104	344.0	COG1129@1|root,COG1129@2|Bacteria,2G7M7@200795|Chloroflexi	200795|Chloroflexi	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
LZS2_k127_71379_7	926550.CLDAP_19660	3.405e-109	362.0	COG1172@1|root,COG1172@2|Bacteria,2G6A4@200795|Chloroflexi	200795|Chloroflexi	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS2_k127_71379_6	547042.BACCOPRO_03195	8.584e-117	387.0	COG0407@1|root,COG0407@2|Bacteria,4NTJT@976|Bacteroidetes,2FUJS@200643|Bacteroidia,4AQYC@815|Bacteroidaceae	976|Bacteroidetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
LZS2_k127_71379_4	545695.TREAZ_0830	3.487e-123	404.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_71379_11	768706.Desor_3513	3.427e-68	241.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
LZS2_k127_71379_12	926550.CLDAP_13920	2.592e-67	234.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
LZS2_k127_71379_14	203119.Cthe_0261	9.582e-57	205.0	COG0546@1|root,COG0546@2|Bacteria,1V6UK@1239|Firmicutes,24KPU@186801|Clostridia,3WII6@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS2_k127_71379_10	1499967.BAYZ01000073_gene2018	6.475e-75	263.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25,Methyltransf_31
LZS2_k127_71379_5	926560.KE387027_gene288	5.071e-120	394.0	COG0150@1|root,COG0150@2|Bacteria,1WIP0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS2_k127_71379_1	1121468.AUBR01000017_gene2358	2.811e-148	482.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,42FB3@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
LZS2_k127_71379_13	272844.PAB1077	4.348e-60	211.0	COG0041@1|root,arCOG02464@2157|Archaea,2XU0P@28890|Euryarchaeota,24415@183968|Thermococci	183968|Thermococci	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
LZS2_k127_71379_0	329726.AM1_2613	6.051e-151	492.0	COG0034@1|root,COG0034@2|Bacteria,1G1C9@1117|Cyanobacteria	1117|Cyanobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
LZS2_k127_71379_3	670487.Ocepr_0686	3.968e-126	410.0	COG0152@1|root,COG0152@2|Bacteria,1WI4Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
LZS2_k127_7144072_0	925409.KI911562_gene794	5.31e-114	378.0	COG3250@1|root,COG3250@2|Bacteria,4NESZ@976|Bacteroidetes,1IQAJ@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
LZS2_k127_7144072_1	118168.MC7420_1011	1.843e-88	307.0	COG0642@1|root,COG2205@2|Bacteria,1G0YJ@1117|Cyanobacteria,1H7ER@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_7144072_2	1128421.JAGA01000002_gene1073	4.001e-33	141.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF4349
LZS2_k127_7163785_0	926569.ANT_27910	1.338e-135	443.0	COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS2_k127_7163785_1	926569.ANT_27900	3.531e-34	134.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS2_k127_7168692_1	660470.Theba_0854	1.914e-19	89.0	COG0745@1|root,COG0745@2|Bacteria	660470.Theba_0854|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7168692_0	880073.Calab_1764	4.73e-155	511.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_7168692_2	1173027.Mic7113_4814	3.038e-14	74.0	COG0286@1|root,COG0286@2|Bacteria,1G2KQ@1117|Cyanobacteria,1H8KX@1150|Oscillatoriales	1117|Cyanobacteria	V	Type I restriction-modification system methyltransferase subunit	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
LZS2_k127_7171536_1	926550.CLDAP_21560	2.757e-46	184.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_7171536_0	502025.Hoch_6548	1.993e-85	296.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,43CYW@68525|delta/epsilon subdivisions,2X872@28221|Deltaproteobacteria,2Z18H@29|Myxococcales	1224|Proteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS_4,Response_reg,SpoIIE
LZS2_k127_7171536_2	326427.Cagg_0485	9.034e-38	160.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
LZS2_k127_7186834_4	1128421.JAGA01000002_gene1800	9.344e-49	178.0	COG2166@1|root,COG2166@2|Bacteria	2|Bacteria	S	iron-sulfur cluster assembly	sufE	-	-	ko:K02426,ko:K07125	-	-	-	-	ko00000	-	-	-	SufE
LZS2_k127_7186834_5	1173028.ANKO01000214_gene6269	2.268e-31	128.0	COG0745@1|root,COG0745@2|Bacteria,1G9E7@1117|Cyanobacteria,1HD4Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_7186834_3	56110.Oscil6304_3144	2.257e-68	237.0	COG1776@1|root,COG1776@2|Bacteria,1G5NU@1117|Cyanobacteria,1HB75@1150|Oscillatoriales	1117|Cyanobacteria	NT	Chemotaxis protein CheC, inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
LZS2_k127_7186834_2	1173028.ANKO01000056_gene2163	4.839e-100	347.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HH3F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
LZS2_k127_7186834_0	929556.Solca_3209	0.0	1615.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,1IR6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS2_k127_7186834_1	324602.Caur_2320	7.138e-152	488.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,374WK@32061|Chloroflexia	32061|Chloroflexia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
LZS2_k127_7234943_2	1266925.JHVX01000001_gene2544	1.176e-54	194.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2VHW5@28216|Betaproteobacteria,372T7@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Alpha-amylase domain	aglA	-	3.2.1.10,3.2.1.20	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
LZS2_k127_7234943_1	926554.KI912671_gene402	3.753e-130	429.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS2_k127_7234943_10	926550.CLDAP_00390	2.15e-07	61.0	COG0454@1|root,COG0456@2|Bacteria,2G9QT@200795|Chloroflexi	200795|Chloroflexi	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_7234943_8	869213.JCM21142_31344	2.049e-19	92.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,47TK7@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
LZS2_k127_7234943_6	4155.Migut.H00032.1.p	1.229e-26	116.0	COG1100@1|root,KOG0098@2759|Eukaryota,37P81@33090|Viridiplantae,3GF17@35493|Streptophyta,44FQD@71274|asterids	35493|Streptophyta	U	Rab subfamily of small GTPases	-	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0008150,GO:0009507,GO:0009536,GO:0012505,GO:0017076,GO:0019001,GO:0030100,GO:0031410,GO:0031982,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032879,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051049,GO:0051128,GO:0060627,GO:0065007,GO:0097159,GO:0097367,GO:0097708,GO:1901265,GO:1901363	-	ko:K07877	ko04152,map04152	-	-	-	ko00000,ko00001,ko04031,ko04131,ko04147	-	-	-	Ras
LZS2_k127_7234943_0	880073.Calab_1764	2.362e-158	527.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_7234943_7	324602.Caur_1383	1.245e-26	118.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
LZS2_k127_7234943_4	357808.RoseRS_1088	4.692e-48	182.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_7234943_9	1173028.ANKO01000195_gene5994	1.583e-18	97.0	COG2202@1|root,COG3829@1|root,COG3920@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG3920@2|Bacteria,COG4191@2|Bacteria,1GHCI@1117|Cyanobacteria,1H8J3@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9
LZS2_k127_7234943_5	926569.ANT_19700	3.92e-33	136.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS2_k127_7234943_3	765420.OSCT_1789	1.852e-49	179.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,374WG@32061|Chloroflexia	32061|Chloroflexia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
LZS2_k127_7269308_2	926569.ANT_16940	5.33e-57	209.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_7269308_4	326427.Cagg_1228	8.856e-30	124.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi,375WR@32061|Chloroflexia	32061|Chloroflexia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
LZS2_k127_7269308_5	1206731.BAGB01000171_gene4677	2.802e-28	119.0	COG3787@1|root,COG3787@2|Bacteria,2IHVY@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0306 family	-	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
LZS2_k127_7269308_1	402777.KB235903_gene1332	2.393e-70	244.0	COG1279@1|root,COG1279@2|Bacteria,1GQJ3@1117|Cyanobacteria,1HHX6@1150|Oscillatoriales	1117|Cyanobacteria	S	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
LZS2_k127_7269308_3	1121127.JAFA01000029_gene2610	2.645e-40	155.0	COG1522@1|root,COG1522@2|Bacteria,1RI47@1224|Proteobacteria,2VT2Z@28216|Betaproteobacteria,1K7G5@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
LZS2_k127_7269308_6	926550.CLDAP_23360	1.382e-12	80.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8QX@200795|Chloroflexi	200795|Chloroflexi	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
LZS2_k127_7269308_0	926550.CLDAP_23290	2.299e-205	654.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_7279583_3	395961.Cyan7425_0521	9.081e-70	244.0	COG0500@1|root,COG1404@1|root,COG1404@2|Bacteria,COG2226@2|Bacteria,1G2T7@1117|Cyanobacteria	1117|Cyanobacteria	O	Cyanobactin maturation protease, PatA PatG family	acyG	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,Peptidase_S8
LZS2_k127_7279583_7	383372.Rcas_1372	1.193e-23	113.0	COG1366@1|root,COG2202@1|root,COG3829@1|root,COG1366@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,2G9FS@200795|Chloroflexi,376CB@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	PAS_4,STAS
LZS2_k127_7279583_5	671143.DAMO_0611	6.328e-63	235.0	COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
LZS2_k127_7279583_9	312284.A20C1_10870	1.701e-15	86.0	2EA1Q@1|root,33470@2|Bacteria,2HCTN@201174|Actinobacteria,3UXRI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxD
LZS2_k127_7279583_2	765420.OSCT_1682	2.134e-70	246.0	COG3222@1|root,COG3222@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
LZS2_k127_7279583_4	357808.RoseRS_2429	4.311e-69	239.0	COG0494@1|root,COG0494@2|Bacteria,2G7A1@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
LZS2_k127_7279583_6	1380390.JIAT01000009_gene840	2.037e-36	147.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4CQ49@84995|Rubrobacteria	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS2_k127_7279583_11	671143.DAMO_0856	0.0006648	44.0	COG1522@1|root,COG1522@2|Bacteria	671143.DAMO_0856|-	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7279583_0	765420.OSCT_1683	4.235e-114	373.0	COG0535@1|root,COG0535@2|Bacteria,2GB36@200795|Chloroflexi,377U5@32061|Chloroflexia	32061|Chloroflexia	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Radical_SAM
LZS2_k127_7279583_1	426117.M446_4900	3.752e-89	308.0	COG0535@1|root,COG0535@2|Bacteria,1NJZV@1224|Proteobacteria,2U4H8@28211|Alphaproteobacteria,1JSDQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS2_k127_7279583_8	665571.STHERM_c19260	1.224e-18	86.0	COG0708@1|root,COG0708@2|Bacteria,2J62E@203691|Spirochaetes	203691|Spirochaetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
LZS2_k127_7282363_16	592015.HMPREF1705_01851	8.529e-05	48.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,3TAPD@508458|Synergistetes	508458|Synergistetes	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
LZS2_k127_7282363_11	926569.ANT_17810	1.633e-47	175.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
LZS2_k127_7282363_1	926569.ANT_17820	2.793e-263	820.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	-	-	1.6.5.3	ko:K00335,ko:K05587	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
LZS2_k127_7282363_4	926569.ANT_09680	2.42e-220	701.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
LZS2_k127_7282363_7	926569.ANT_09670	8.192e-88	292.0	COG1941@1|root,COG1941@2|Bacteria,2G6MH@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.12.1.2,1.8.98.5	ko:K14128,ko:K18007	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
LZS2_k127_7282363_2	926569.ANT_09660	2.011e-245	764.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
LZS2_k127_7282363_14	1131462.DCF50_p1175	3.972e-27	112.0	COG2261@1|root,COG2261@2|Bacteria,1VEUE@1239|Firmicutes,24RAN@186801|Clostridia,265WV@186807|Peptococcaceae	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
LZS2_k127_7282363_15	582515.KR51_00012760	4.984e-22	101.0	COG1357@1|root,COG1357@2|Bacteria,1G42W@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_7282363_13	926569.ANT_09650	9.97e-38	147.0	COG0680@1|root,COG0680@2|Bacteria,2G9H7@200795|Chloroflexi	200795|Chloroflexi	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	hoxW	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7282363_12	1005048.CFU_1982	1.322e-44	166.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,2WGT1@28216|Betaproteobacteria,474W2@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS2_k127_7282363_9	335543.Sfum_2712	6.766e-71	245.0	COG1905@1|root,COG1905@2|Bacteria,1MYGQ@1224|Proteobacteria,42SF4@68525|delta/epsilon subdivisions,2WP44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	hoxE	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
LZS2_k127_7282363_0	926550.CLDAP_28490	1.933e-275	856.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	hoxF	-	1.6.5.3	ko:K00335,ko:K05587	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
LZS2_k127_7282363_5	926550.CLDAP_28480	8.847e-124	399.0	COG3383@1|root,COG3383@2|Bacteria,2G65A@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	hoxU	-	1.6.5.3	ko:K05588	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_9,NADH-G_4Fe-4S_3
LZS2_k127_7282363_8	653733.Selin_1985	9.365e-78	263.0	COG1941@1|root,COG1941@2|Bacteria	2|Bacteria	C	coenzyme F420 hydrogenase activity	hoxY	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	iJN678.hoxY	Oxidored_q6
LZS2_k127_7282363_3	926550.CLDAP_28460	5.283e-229	717.0	COG3259@1|root,COG3259@2|Bacteria,2G68W@200795|Chloroflexi	200795|Chloroflexi	C	PFAM nickel-dependent hydrogenase, large subunit	-	-	1.12.1.2,1.8.98.5	ko:K00436,ko:K14126	ko00680,map00680	-	R00019,R00700,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
LZS2_k127_7282363_6	1121423.JONT01000002_gene2286	1.991e-107	355.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,260NW@186807|Peptococcaceae	186801|Clostridia	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
LZS2_k127_7282363_10	568816.Acin_2036	4.111e-48	177.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,4H2A8@909932|Negativicutes	909932|Negativicutes	C	glutamate synthase (NADPH)	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,Pyr_redox_2
LZS2_k127_7298392_2	317936.Nos7107_0112	2.69e-52	205.0	COG2304@1|root,COG3170@1|root,COG4719@1|root,COG4932@1|root,COG2304@2|Bacteria,COG3170@2|Bacteria,COG4719@2|Bacteria,COG4932@2|Bacteria,1GQNV@1117|Cyanobacteria	1117|Cyanobacteria	MN	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS2_k127_7298392_6	1161413.HMPREF1510_0977	0.0004761	53.0	COG1361@1|root,COG1361@2|Bacteria,1UN7S@1239|Firmicutes	1239|Firmicutes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS2_k127_7298392_5	316274.Haur_3316	2.021e-15	85.0	COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi,375JA@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase C60, sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
LZS2_k127_7298392_4	926550.CLDAP_21830	5.769e-16	87.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7298392_1	926569.ANT_20430	8.084e-54	196.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi	200795|Chloroflexi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
LZS2_k127_7298392_3	926550.CLDAP_00490	3.241e-30	122.0	COG1977@1|root,COG1977@2|Bacteria,2G74G@200795|Chloroflexi	200795|Chloroflexi	H	PFAM thiamineS protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS2_k127_7298392_0	926550.CLDAP_00500	7.825e-103	341.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2G5TN@200795|Chloroflexi	200795|Chloroflexi	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
LZS2_k127_7328071_4	926569.ANT_27070	2.218e-56	205.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_7328071_0	926569.ANT_27060	3.843e-101	336.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_7328071_2	926569.ANT_27050	3.879e-67	233.0	COG1695@1|root,COG1695@2|Bacteria,2G9N5@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
LZS2_k127_7328071_7	1173029.JH980292_gene2865	3.595e-10	61.0	COG1487@1|root,COG1487@2|Bacteria,1GKFT@1117|Cyanobacteria,1HDWG@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS2_k127_7328071_5	926569.ANT_11490	2.754e-23	116.0	COG1807@1|root,COG1807@2|Bacteria,2G9HX@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7328071_6	926550.CLDAP_04460	1.183e-11	78.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7328071_1	1499967.BAYZ01000095_gene4218	3.206e-92	313.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
LZS2_k127_7328071_3	1167006.UWK_00149	5.783e-61	220.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria,2MI6A@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
LZS2_k127_7352072_8	357808.RoseRS_4042	7.318e-29	118.0	COG0489@1|root,COG0489@2|Bacteria,2G5WM@200795|Chloroflexi,375EN@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM capsular exopolysaccharide family	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,ParA
LZS2_k127_7352072_4	926550.CLDAP_01220	1.571e-47	179.0	COG3944@1|root,COG3944@2|Bacteria,2G9GX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
LZS2_k127_7352072_5	926550.CLDAP_39150	4.927e-44	168.0	COG3944@1|root,COG3944@2|Bacteria,2G7A7@200795|Chloroflexi	200795|Chloroflexi	M	Lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
LZS2_k127_7352072_6	1173028.ANKO01000106_gene313	6.412e-43	168.0	COG0515@1|root,COG1357@1|root,COG0515@2|Bacteria,COG1357@2|Bacteria,1G08U@1117|Cyanobacteria,1H85Z@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pkinase
LZS2_k127_7352072_3	1499967.BAYZ01000074_gene2129	2.428e-86	289.0	COG0503@1|root,COG0503@2|Bacteria	2|Bacteria	F	purine ribonucleoside salvage	xpt	GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.22,2.4.2.7	ko:K00759,ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R00190,R01229,R02142,R04378	RC00063,RC00122	ko00000,ko00001,ko01000,ko04147	-	-	iYO844.BSU22070	Pribosyltran
LZS2_k127_7352072_0	639282.DEFDS_0470	3.694e-197	627.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GEZG@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
LZS2_k127_7352072_10	765420.OSCT_2950	5.181e-20	106.0	COG0631@1|root,COG0631@2|Bacteria,2G72P@200795|Chloroflexi,374Z2@32061|Chloroflexia	32061|Chloroflexia	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7352072_7	246197.MXAN_0347	1.06e-38	160.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1QX6W@1224|Proteobacteria,42ZK5@68525|delta/epsilon subdivisions,2WUSH@28221|Deltaproteobacteria,2YXKX@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4
LZS2_k127_7352072_11	1148.1653383	2.964e-17	89.0	COG1357@1|root,COG1357@2|Bacteria,1G4CB@1117|Cyanobacteria,1H664@1142|Synechocystis	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_7352072_1	526227.Mesil_0256	3.113e-170	586.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
LZS2_k127_7352072_9	1128421.JAGA01000004_gene2687	1.558e-20	98.0	2AW22@1|root,31MWT@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1360)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1360
LZS2_k127_7352072_2	880073.Calab_1860	4.628e-90	304.0	COG2183@1|root,COG2183@2|Bacteria,2NP2S@2323|unclassified Bacteria	2|Bacteria	K	Tex-like protein N-terminal domain	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
LZS2_k127_7360301_5	357808.RoseRS_1520	5.639e-16	85.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Peptidase_C11
LZS2_k127_7360301_4	926550.CLDAP_39570	9.118e-64	228.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	pyrK	-	1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1
LZS2_k127_7360301_2	926550.CLDAP_25040	5.233e-110	364.0	COG0167@1|root,COG0167@2|Bacteria,2G6RH@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS2_k127_7360301_0	1128421.JAGA01000003_gene3014	1.899e-149	478.0	COG0540@1|root,COG0540@2|Bacteria,2NNPZ@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z5856	OTCace,OTCace_N
LZS2_k127_7360301_1	926550.CLDAP_25050	8.309e-148	483.0	COG0284@1|root,COG0461@1|root,COG0284@2|Bacteria,COG0461@2|Bacteria,2G692@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
LZS2_k127_7360301_3	1128421.JAGA01000003_gene3013	1.26e-91	309.0	COG0044@1|root,COG0044@2|Bacteria,2NNWP@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS2_k127_736809_2	926550.CLDAP_40550	1.613e-48	177.0	COG0652@1|root,COG0652@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
LZS2_k127_736809_0	324602.Caur_2312	1.407e-148	477.0	COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi,375GP@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS2_k127_736809_1	485913.Krac_0962	2.135e-67	238.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
LZS2_k127_7372128_0	935948.KE386495_gene1456	0.0	1056.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,42FW8@68295|Thermoanaerobacterales	186801|Clostridia	G	glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
LZS2_k127_7372128_3	331678.Cphamn1_1410	7.271e-55	198.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
LZS2_k127_7372128_6	765914.ThisiDRAFT_2853	9.332e-07	54.0	COG3385@1|root,COG3385@2|Bacteria,1QFKR@1224|Proteobacteria,1SCE4@1236|Gammaproteobacteria,1X0CD@135613|Chromatiales	135613|Chromatiales	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
LZS2_k127_7372128_4	525904.Tter_2549	1.199e-45	181.0	COG3850@1|root,COG3850@2|Bacteria,2NS42@2323|unclassified Bacteria	2|Bacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K03406,ko:K07673,ko:K07675	ko02020,ko02030,map02020,map02030	M00471,M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,LapD_MoxY_N
LZS2_k127_7372128_1	697282.Mettu_0616	6.251e-155	498.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
LZS2_k127_7372128_2	1449126.JQKL01000042_gene1033	3.279e-65	229.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,269AP@186813|unclassified Clostridiales	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_7372128_5	926569.ANT_18820	8.013e-29	121.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	-	-	-	ko:K06039,ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
LZS2_k127_737564_2	338969.Rfer_2741	1.775e-24	110.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_737564_0	926550.CLDAP_22740	1.889e-157	504.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
LZS2_k127_737564_1	1122223.KB890696_gene261	7.731e-72	255.0	COG1609@1|root,COG1609@2|Bacteria,1WM4T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_7381102_2	338963.Pcar_2120	8.609e-111	365.0	COG0189@1|root,COG0189@2|Bacteria,1QZ5P@1224|Proteobacteria,42PFH@68525|delta/epsilon subdivisions,2X7RD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HJ	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
LZS2_k127_7381102_5	383372.Rcas_2219	6.023e-29	135.0	COG4886@1|root,COG4886@2|Bacteria,2G906@200795|Chloroflexi,375M2@32061|Chloroflexia	32061|Chloroflexia	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7381102_3	926550.CLDAP_08620	2.087e-57	203.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi	200795|Chloroflexi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
LZS2_k127_7381102_1	552811.Dehly_0249	6.177e-124	417.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi,34D4S@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
LZS2_k127_7381102_7	926569.ANT_20470	2.455e-07	57.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS2_k127_7381102_6	926569.ANT_20480	9.628e-08	60.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7381102_8	309801.trd_1498	2.6e-06	52.0	2B6U1@1|root,31ZTE@2|Bacteria,2GBBT@200795|Chloroflexi,27YPW@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7381102_0	926569.ANT_14740	1.224e-129	426.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
LZS2_k127_7381102_4	555079.Toce_1130	1.366e-53	192.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS2_k127_738617_9	234267.Acid_7126	5.673e-29	116.0	COG0673@1|root,COG0673@2|Bacteria,3Y7D9@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_738617_4	1304880.JAGB01000001_gene541	7.998e-77	263.0	COG3828@1|root,COG3828@2|Bacteria,1V459@1239|Firmicutes,25DAB@186801|Clostridia	186801|Clostridia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
LZS2_k127_738617_1	935948.KE386494_gene166	1.781e-96	326.0	COG1028@1|root,COG1028@2|Bacteria,1TPTY@1239|Firmicutes,24HN8@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_738617_2	1499967.BAYZ01000073_gene2029	1.356e-93	312.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS2_k127_738617_0	1449063.JMLS01000008_gene4929	1.811e-185	585.0	COG0673@1|root,COG0673@2|Bacteria,1TNYR@1239|Firmicutes,4HAZU@91061|Bacilli,26UFG@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_738617_11	935948.KE386495_gene1662	1.717e-10	63.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,42HF3@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
LZS2_k127_738617_10	926550.CLDAP_04250	1.203e-27	115.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi	200795|Chloroflexi	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
LZS2_k127_738617_8	997346.HMPREF9374_2513	5.224e-30	119.0	COG0759@1|root,COG0759@2|Bacteria,1UEB1@1239|Firmicutes,4I3UQ@91061|Bacilli,27D7Y@186824|Thermoactinomycetaceae	91061|Bacilli	S	Haemolytic	-	-	-	-	-	-	-	-	-	-	-	-	Haemolytic
LZS2_k127_738617_6	3218.PP1S381_17V6.1	1.599e-63	235.0	COG0706@1|root,KOG1239@2759|Eukaryota,37IIV@33090|Viridiplantae,3GB9B@35493|Streptophyta	35493|Streptophyta	OU	Inner membrane protein PPF-1	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009657,GO:0009668,GO:0009987,GO:0010027,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0017038,GO:0019904,GO:0022607,GO:0031976,GO:0031984,GO:0032991,GO:0033036,GO:0033365,GO:0034357,GO:0034613,GO:0042651,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045036,GO:0045038,GO:0045184,GO:0046907,GO:0050789,GO:0050793,GO:0050794,GO:0051179,GO:0051234,GO:0051259,GO:0051291,GO:0051641,GO:0051649,GO:0055035,GO:0055085,GO:0061024,GO:0065002,GO:0065003,GO:0065007,GO:0070206,GO:0070208,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072596,GO:0072598,GO:0072657,GO:0090150,GO:0090342	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
LZS2_k127_738617_7	926569.ANT_22890	1.424e-49	186.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
LZS2_k127_738617_3	926550.CLDAP_04300	1.777e-87	297.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS2_k127_738617_5	309801.trd_1054	1.626e-72	255.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi,27XFW@189775|Thermomicrobia	189775|Thermomicrobia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
LZS2_k127_7388759_1	926550.CLDAP_23270	2.09e-62	221.0	COG0463@1|root,COG0463@2|Bacteria,2GBP0@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS2_k127_7388759_3	756067.MicvaDRAFT_4224	3.398e-08	67.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria,1H88B@1150|Oscillatoriales	1117|Cyanobacteria	M	Lipid A core - O-antigen ligase	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
LZS2_k127_7388759_2	357808.RoseRS_1718	4.345e-48	194.0	COG1287@1|root,COG1807@1|root,COG1287@2|Bacteria,COG1807@2|Bacteria,2GAJ2@200795|Chloroflexi,3770X@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7388759_0	926569.ANT_05150	3.581e-64	235.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7405830_1	756067.MicvaDRAFT_1841	2.171e-43	161.0	COG1672@1|root,COG1672@2|Bacteria,1G15R@1117|Cyanobacteria,1HHE7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7405830_0	118168.MC7420_3393	3.278e-219	709.0	COG1672@1|root,COG1672@2|Bacteria,1G4AU@1117|Cyanobacteria,1HAF9@1150|Oscillatoriales	1117|Cyanobacteria	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
LZS2_k127_7415225_2	765420.OSCT_1451	2.037e-43	166.0	COG1321@1|root,COG1321@2|Bacteria,2GBR2@200795|Chloroflexi,3766X@32061|Chloroflexia	32061|Chloroflexia	K	PFAM iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
LZS2_k127_7415225_3	765420.OSCT_1175	8.88e-16	81.0	COG1918@1|root,COG1918@2|Bacteria,2G9MI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
LZS2_k127_7415225_1	926550.CLDAP_17810	1.177e-57	206.0	COG0370@1|root,COG0370@2|Bacteria,2G8KC@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM small GTP-binding protein	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_N
LZS2_k127_7415225_0	326427.Cagg_3546	7.711e-156	503.0	COG0370@1|root,COG0370@2|Bacteria,2G5RW@200795|Chloroflexi,3761U@32061|Chloroflexia	32061|Chloroflexia	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
LZS2_k127_7453136_10	1499967.BAYZ01000104_gene3618	3.71e-59	207.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
LZS2_k127_7453136_1	697281.Mahau_1300	4.053e-182	587.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42EXP@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_7453136_12	1123400.KB904766_gene2962	1.019e-11	73.0	290RU@1|root,2ZNDZ@2|Bacteria,1P98B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7453136_8	926550.CLDAP_23150	1.31e-106	374.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_7453136_11	926550.CLDAP_28170	2.419e-57	214.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
LZS2_k127_7453136_2	1499967.BAYZ01000095_gene4185	3.065e-157	510.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_7453136_4	1499967.BAYZ01000095_gene4184	4.009e-147	471.0	COG1175@1|root,COG1175@2|Bacteria,2NQCB@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
LZS2_k127_7453136_6	1499967.BAYZ01000095_gene4183	5.32e-138	445.0	COG0395@1|root,COG0395@2|Bacteria,2NPII@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	yesQ	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	iYO844.BSU06990	BPD_transp_1
LZS2_k127_7453136_0	1499967.BAYZ01000095_gene4182	1.378e-202	639.0	COG1486@1|root,COG1486@2|Bacteria,2NQP2@2323|unclassified Bacteria	2|Bacteria	G	Family 4 glycosyl hydrolase	lplD	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
LZS2_k127_7453136_7	1120972.AUMH01000005_gene868	1.459e-129	425.0	COG0673@1|root,COG0673@2|Bacteria,1UWRF@1239|Firmicutes,4I413@91061|Bacilli,27AIP@186823|Alicyclobacillaceae	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_7453136_3	1128421.JAGA01000001_gene2100	7.698e-157	502.0	COG0673@1|root,COG0673@2|Bacteria,2NR0C@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_7453136_5	886293.Sinac_0734	1.911e-142	464.0	COG4225@1|root,COG4225@2|Bacteria,2IY9U@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
LZS2_k127_7453136_9	794903.OPIT5_16130	1.509e-90	305.0	COG1028@1|root,COG1028@2|Bacteria,46TD2@74201|Verrucomicrobia,3K7W5@414999|Opitutae	414999|Opitutae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS2_k127_7453136_13	880070.Cycma_4970	1.654e-11	64.0	COG1082@1|root,COG1082@2|Bacteria,4NHJE@976|Bacteroidetes,47NW1@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS2_k127_7524062_1	926550.CLDAP_24400	6.519e-133	432.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi	200795|Chloroflexi	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
LZS2_k127_7524062_0	926569.ANT_00890	2.889e-290	901.0	28I0T@1|root,2Z85H@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4914
LZS2_k127_7524062_3	926569.ANT_17850	1.157e-77	265.0	COG0378@1|root,COG0378@2|Bacteria,2G6EP@200795|Chloroflexi	200795|Chloroflexi	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K03189,ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
LZS2_k127_7524062_5	552811.Dehly_1408	1.499e-34	135.0	COG0375@1|root,COG0375@2|Bacteria,2G77T@200795|Chloroflexi,34DD7@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
LZS2_k127_7524062_4	608506.COB47_1747	2.661e-50	183.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
LZS2_k127_7524062_2	1125863.JAFN01000001_gene3450	2.309e-129	419.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
LZS2_k127_7538224_0	1501230.ET33_02970	1.374e-54	207.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
LZS2_k127_7541935_2	273068.TTE1217	1.392e-128	417.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS2_k127_7541935_5	926569.ANT_02700	6.548e-37	143.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
LZS2_k127_7541935_0	926550.CLDAP_31970	0.0	1470.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
LZS2_k127_7541935_1	926569.ANT_08730	0.0	1060.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
LZS2_k127_7541935_3	926550.CLDAP_22140	6.471e-62	221.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi	200795|Chloroflexi	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
LZS2_k127_7541935_4	926569.ANT_08630	3.498e-39	150.0	COG0295@1|root,COG0295@2|Bacteria,2G7AW@200795|Chloroflexi	200795|Chloroflexi	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
LZS2_k127_7541935_6	1382306.JNIM01000001_gene2574	5.272e-29	121.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi	200795|Chloroflexi	S	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
LZS2_k127_7545089_0	1121918.ARWE01000001_gene135	4.098e-98	332.0	COG3366@1|root,COG3366@2|Bacteria,1P2FE@1224|Proteobacteria,42MJM@68525|delta/epsilon subdivisions,2WKGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM nucleoside recognition domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gate
LZS2_k127_7545089_2	876044.IMCC3088_1716	1.759e-54	197.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,1RPZ3@1236|Gammaproteobacteria,1J776@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
LZS2_k127_7545089_1	945713.IALB_1503	7.038e-62	225.0	COG0618@1|root,COG0618@2|Bacteria	2|Bacteria	S	phosphoesterase RecJ domain protein	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
LZS2_k127_7545089_3	309801.trd_0699	9.479e-17	83.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi,27YP8@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
LZS2_k127_7552248_1	445961.IW15_02135	5.289e-13	74.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I2T3@117743|Flavobacteriia,3ZS40@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
LZS2_k127_7552248_0	1167006.UWK_00703	3.226e-155	509.0	COG0038@1|root,COG0517@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,COG0569@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
LZS2_k127_7589708_4	926550.CLDAP_03020	2.067e-36	151.0	COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi	200795|Chloroflexi	M	peptidase C60 sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
LZS2_k127_7589708_1	449447.MAE_20230	1.787e-102	336.0	COG3506@1|root,COG3506@2|Bacteria,1G5CJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
LZS2_k127_7589708_2	698761.RTCIAT899_CH12370	4.663e-80	273.0	COG3382@1|root,COG3382@2|Bacteria,1NXK4@1224|Proteobacteria,2URVW@28211|Alphaproteobacteria,4BN1F@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
LZS2_k127_7589708_0	382464.ABSI01000009_gene3938	2.606e-109	358.0	COG0106@1|root,COG0106@2|Bacteria,46U39@74201|Verrucomicrobia,2ITHN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Histidine biosynthesis protein	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS2_k127_7599597_1	1173027.Mic7113_1748	3.19e-133	433.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H837@1150|Oscillatoriales	1117|Cyanobacteria	Q	Non-ribosomal peptide synthetase modules and related	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ
LZS2_k127_7599597_0	1173024.KI912152_gene784	0.0	1194.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_25,PP-binding,Thioesterase
LZS2_k127_7609337_2	330214.NIDE0225	5.538e-38	147.0	COG1007@1|root,COG1007@2|Bacteria,3J0FN@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS2_k127_7609337_1	926569.ANT_01450	1.446e-48	181.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
LZS2_k127_7609337_0	926550.CLDAP_19610	2.688e-78	270.0	COG0589@1|root,COG0589@2|Bacteria,2GBJZ@200795|Chloroflexi	200795|Chloroflexi	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_7626079_1	926569.ANT_12980	4.016e-32	129.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
LZS2_k127_7626079_0	1122223.KB890701_gene2224	2.047e-81	278.0	COG0454@1|root,COG0456@2|Bacteria,1WMPD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,FR47
LZS2_k127_7626079_2	479434.Sthe_0403	1.57e-25	111.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS2_k127_7644529_0	926550.CLDAP_11920	1.596e-27	125.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,PTPS_related
LZS2_k127_7644529_1	357808.RoseRS_1037	1.532e-15	90.0	COG1928@1|root,COG1928@2|Bacteria,2G8YA@200795|Chloroflexi,375IA@32061|Chloroflexia	32061|Chloroflexia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_766093_3	479434.Sthe_1208	1.454e-20	95.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,27XW2@189775|Thermomicrobia	189775|Thermomicrobia	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
LZS2_k127_766093_0	1041930.Mtc_0845	2.712e-51	201.0	COG0642@1|root,arCOG02338@1|root,arCOG02338@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,2NBMD@224756|Methanomicrobia	224756|Methanomicrobia	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS2_k127_766093_1	1410620.SHLA_46c000250	4.182e-41	164.0	COG0524@1|root,COG0524@2|Bacteria,1Q2F5@1224|Proteobacteria,2V669@28211|Alphaproteobacteria,4BIVF@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS2_k127_766093_2	926569.ANT_08190	4.34e-26	109.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS2_k127_7666561_0	574966.KB898660_gene647	1.661e-138	448.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,1RNZN@1236|Gammaproteobacteria,1XJKW@135619|Oceanospirillales	135619|Oceanospirillales	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
LZS2_k127_7666561_3	1385520.N802_06495	3.517e-10	74.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4FFAH@85021|Intrasporangiaceae	201174|Actinobacteria	Q	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_7666561_1	926550.CLDAP_02170	3.456e-23	107.0	arCOG03391@1|root,33KRQ@2|Bacteria	2|Bacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
LZS2_k127_7666561_2	1385514.N782_02325	1.241e-13	75.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4I3EY@91061|Bacilli,2YBI5@289201|Pontibacillus	91061|Bacilli	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
LZS2_k127_7666561_4	1296416.JACB01000026_gene4009	2.638e-08	60.0	COG0823@1|root,COG0823@2|Bacteria,4NYXJ@976|Bacteroidetes,1IHT2@117743|Flavobacteriia,2YJBR@290174|Aquimarina	976|Bacteroidetes	U	Domain of unknown function (DUF5050)	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS2_k127_7674364_1	1123248.KB893348_gene312	6.6e-87	291.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,1IPXJ@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_7674364_2	765420.OSCT_0408	7.842e-63	231.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi,37548@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
LZS2_k127_7674364_3	300852.55773042	4.396e-35	140.0	COG1403@1|root,COG1403@2|Bacteria,1WICD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
LZS2_k127_7674364_0	314278.NB231_03015	2.306e-123	413.0	2C40F@1|root,33WUG@2|Bacteria,1NWBW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7674364_4	237368.SCABRO_01122	8.566e-17	81.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
LZS2_k127_7674444_0	709991.Odosp_3249	6.479e-197	618.0	COG0205@1|root,COG0205@2|Bacteria,4NFPT@976|Bacteroidetes,2FMJ9@200643|Bacteroidia,22ZT1@171551|Porphyromonadaceae	976|Bacteroidetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS2_k127_7674444_6	926569.ANT_27110	2.492e-06	57.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7674444_3	926569.ANT_01640	3.763e-52	191.0	COG0500@1|root,COG2226@2|Bacteria,2G8IN@200795|Chloroflexi	200795|Chloroflexi	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
LZS2_k127_7674444_5	717773.Thicy_1519	7.59e-29	122.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,460SD@72273|Thiotrichales	72273|Thiotrichales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
LZS2_k127_7674444_4	324602.Caur_2153	2.225e-39	154.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3,HTH_31
LZS2_k127_7674444_2	1121403.AUCV01000054_gene2598	2.448e-94	314.0	COG2220@1|root,COG2220@2|Bacteria,1PFZZ@1224|Proteobacteria,42SXY@68525|delta/epsilon subdivisions,2WPFM@28221|Deltaproteobacteria,2MMG4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
LZS2_k127_7674444_1	926569.ANT_29620	8.241e-144	465.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS2_k127_7680083_2	138119.DSY3656	2.88e-51	184.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,261I1@186807|Peptococcaceae	186801|Clostridia	P	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_7680083_1	926550.CLDAP_19400	2.006e-103	350.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_7680083_3	926550.CLDAP_04490	2.78e-29	134.0	COG0823@1|root,COG3103@1|root,COG0823@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	NLPC_P60,Rick_17kDa_Anti,SH3_3
LZS2_k127_7680083_0	439235.Dalk_0845	1.058e-103	342.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria,2MKSR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
LZS2_k127_7681904_0	264732.Moth_1900	4.869e-108	359.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,25B35@186801|Clostridia,42FFN@68295|Thermoanaerobacterales	186801|Clostridia	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_7681904_1	247490.KSU1_D0844	1.819e-90	308.0	COG1131@1|root,COG1131@2|Bacteria,2J23F@203682|Planctomycetes	203682|Planctomycetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS2_k127_7681904_2	926550.CLDAP_07720	9.887e-73	252.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
LZS2_k127_7706020_0	765420.OSCT_3048	7.212e-66	252.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2GBRA@200795|Chloroflexi,3768N@32061|Chloroflexia	32061|Chloroflexia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_7706020_1	530564.Psta_2541	5.847e-08	62.0	COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
LZS2_k127_7723055_0	1382306.JNIM01000001_gene2807	2.615e-200	634.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi	2|Bacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK3	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
LZS2_k127_7723055_3	1382306.JNIM01000001_gene2806	2.372e-117	385.0	COG2390@1|root,COG2390@2|Bacteria,2G8CS@200795|Chloroflexi	200795|Chloroflexi	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sugar-bind
LZS2_k127_7723055_4	1195236.CTER_4231	2.469e-12	76.0	COG5618@1|root,COG5618@2|Bacteria,1V221@1239|Firmicutes,24G1Q@186801|Clostridia	186801|Clostridia	S	Predicted periplasmic lipoprotein (DUF2291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2291
LZS2_k127_7723055_1	1382306.JNIM01000001_gene2804	1.305e-193	617.0	COG1129@1|root,COG1129@2|Bacteria	2|Bacteria	G	ABC transporter	rbsA_1	-	3.6.3.17	ko:K10441,ko:K17204	ko02010,map02010	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	ABC_tran
LZS2_k127_7723055_2	1382306.JNIM01000001_gene2803	9.922e-118	391.0	COG1172@1|root,COG1172@2|Bacteria,2G6A4@200795|Chloroflexi	200795|Chloroflexi	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS2_k127_7735755_5	357808.RoseRS_1037	1.327e-11	78.0	COG1928@1|root,COG1928@2|Bacteria,2G8YA@200795|Chloroflexi,375IA@32061|Chloroflexia	32061|Chloroflexia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7735755_4	357808.RoseRS_1951	1.93e-16	92.0	COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7735755_3	926550.CLDAP_12950	7.689e-41	154.0	COG3695@1|root,COG3695@2|Bacteria,2G7CY@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
LZS2_k127_7735755_1	324602.Caur_2965	4.782e-94	316.0	COG1806@1|root,COG1806@2|Bacteria,2G8E0@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
LZS2_k127_7735755_6	439235.Dalk_4715	5.175e-09	60.0	COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,42MGR@68525|delta/epsilon subdivisions,2WJSI@28221|Deltaproteobacteria,2MI95@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_7735755_0	1159870.KB907784_gene2625	6.133e-149	479.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2VMBM@28216|Betaproteobacteria,3T2NK@506|Alcaligenaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_7735755_2	595460.RRSWK_04508	3.975e-59	211.0	COG1878@1|root,COG1878@2|Bacteria,2IZXG@203682|Planctomycetes	203682|Planctomycetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
LZS2_k127_774582_2	113355.CM001775_gene344	2.826e-16	81.0	COG1487@1|root,COG1487@2|Bacteria,1G98C@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS2_k127_774582_1	316274.Haur_2274	8.623e-82	279.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi,3773X@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_774582_0	742767.HMPREF9456_02770	3.291e-224	722.0	COG0642@1|root,COG2205@2|Bacteria,4NEZM@976|Bacteroidetes,2FN1Z@200643|Bacteroidia,22X0P@171551|Porphyromonadaceae	976|Bacteroidetes	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
LZS2_k127_7751027_1	316274.Haur_2691	1.034e-21	100.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi,375IM@32061|Chloroflexia	32061|Chloroflexia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS2_k127_7751027_0	926569.ANT_30890	4.244e-66	235.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
LZS2_k127_7762229_0	926569.ANT_27890	3.188e-193	612.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
LZS2_k127_7762229_1	926569.ANT_27900	6.167e-135	441.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS2_k127_7763187_0	485913.Krac_1406	1.482e-107	363.0	COG2801@1|root,COG2801@2|Bacteria,2G9MD@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A9B8L4 Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
LZS2_k127_7763593_2	398767.Glov_1191	2.362e-36	140.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WKKK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM cation diffusion facilitator family transporter	dmeF	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
LZS2_k127_7763593_1	1121413.JMKT01000016_gene29	1.474e-61	215.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42SQK@68525|delta/epsilon subdivisions,2WPK1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Protein-tyrosine phosphatase, low molecular weight	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS2_k127_7763593_0	926550.CLDAP_40600	1.318e-83	280.0	COG0798@1|root,COG0798@2|Bacteria,2G5ZH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
LZS2_k127_7773528_3	316274.Haur_1206	4.671e-33	132.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS2_k127_7773528_1	880073.Calab_0652	3.822e-87	299.0	COG0604@1|root,COG0604@2|Bacteria,2NQR7@2323|unclassified Bacteria	2|Bacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
LZS2_k127_7773528_0	211165.AJLN01000148_gene2390	1.674e-98	329.0	COG0491@1|root,COG0491@2|Bacteria,1G9C5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
LZS2_k127_7773528_2	497964.CfE428DRAFT_1237	1.002e-55	198.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
LZS2_k127_7773882_1	1121396.KB893063_gene1190	4.101e-24	106.0	COG3850@1|root,COG3850@2|Bacteria,1NDQ9@1224|Proteobacteria,42TSU@68525|delta/epsilon subdivisions,2WQCN@28221|Deltaproteobacteria,2MM3Z@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP
LZS2_k127_7773882_0	1267535.KB906767_gene3365	7.365e-226	707.0	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria,2JI0J@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
LZS2_k127_7810539_3	926569.ANT_09860	3.308e-33	135.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yyaR	-	-	ko:K06889,ko:K19273	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
LZS2_k127_7810539_1	926550.CLDAP_25230	1.267e-132	449.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
LZS2_k127_7810539_2	768706.Desor_3513	4.466e-83	285.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
LZS2_k127_7810539_0	926550.CLDAP_01250	1.029e-172	548.0	COG1209@1|root,COG1209@2|Bacteria,2G6MR@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS2_k127_7810539_4	383372.Rcas_3668	1.721e-26	112.0	COG0489@1|root,COG0489@2|Bacteria,2G5WM@200795|Chloroflexi,375EN@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM capsular exopolysaccharide family	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,ParA
LZS2_k127_7814391_5	1034943.BN1094_00264	3.97e-08	63.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,1RNFM@1236|Gammaproteobacteria,1JD3M@118969|Legionellales	118969|Legionellales	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
LZS2_k127_7814391_2	203122.Sde_3845	2.726e-47	192.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Alginate_lyase,CBM_35,CBM_6,F5_F8_type_C,Glyco_hydro_30,Glyco_hydro_30C,Glyco_hydro_76,Melibiase_2
LZS2_k127_7814391_1	383372.Rcas_1611	1.977e-84	287.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
LZS2_k127_7814391_0	383372.Rcas_1610	2.992e-86	292.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
LZS2_k127_7814391_3	926550.CLDAP_00160	3.081e-19	100.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
LZS2_k127_7814391_4	926550.CLDAP_01930	1.16e-17	92.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
LZS2_k127_7839891_3	926550.CLDAP_00150	3.832e-07	63.0	COG0664@1|root,COG0664@2|Bacteria,2G902@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_6,Fer4_7,cNMP_binding
LZS2_k127_7839891_1	1136417.AZWE01000024_gene697	3.708e-11	75.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4DEFF@85008|Micromonosporales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
LZS2_k127_7839891_2	1071073.KI530541_gene3310	2.32e-07	53.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,4HB28@91061|Bacilli,1ZC3P@1386|Bacillus	91061|Bacilli	IQ	Class II Aldolase and Adducin N-terminal domain	yuxG	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
LZS2_k127_7843517_11	926550.CLDAP_34120	2.517e-60	225.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS2_k127_7843517_10	926550.CLDAP_34110	4.525e-68	259.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
LZS2_k127_7843517_0	1128421.JAGA01000003_gene3718	7.618e-224	711.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_7843517_9	1173022.Cri9333_4380	1.029e-70	248.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HAPE@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
LZS2_k127_7843517_5	316274.Haur_0047	8.681e-123	409.0	COG3552@1|root,COG3552@2|Bacteria,2G60I@200795|Chloroflexi,3757T@32061|Chloroflexia	32061|Chloroflexia	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
LZS2_k127_7843517_4	1128421.JAGA01000002_gene1437	2.111e-142	460.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	MA20_34740	-	-	-	-	-	-	-	-	-	-	-	AAA_5
LZS2_k127_7843517_1	926569.ANT_25100	1.81e-206	660.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
LZS2_k127_7843517_12	926550.CLDAP_29940	9.066e-30	132.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7843517_8	1009370.ALO_00310	8.61e-76	266.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H1VB@909932|Negativicutes	909932|Negativicutes	EP	Permease	oppC	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
LZS2_k127_7843517_7	1449126.JQKL01000004_gene567	2.26e-85	296.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,268KP@186813|unclassified Clostridiales	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
LZS2_k127_7843517_6	744872.Spica_2539	2.481e-90	321.0	COG4166@1|root,COG4166@2|Bacteria,2J687@203691|Spirochaetes	203691|Spirochaetes	E	extracellular solute-binding protein, family 5	oppA-1	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
LZS2_k127_7843517_2	309801.trd_1630	5.055e-154	493.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,27XY8@189775|Thermomicrobia	189775|Thermomicrobia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS2_k127_7843517_3	926550.CLDAP_11120	1.681e-151	485.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS2_k127_7850279_0	926569.ANT_15410	2.611e-106	358.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
LZS2_k127_7850279_1	926569.ANT_20860	1.037e-63	223.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
LZS2_k127_7859813_13	1379698.RBG1_1C00001G0158	2.131e-40	160.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
LZS2_k127_7859813_15	1254432.SCE1572_31510	6.182e-24	105.0	COG2204@1|root,COG2204@2|Bacteria,1QWDW@1224|Proteobacteria,43AZ3@68525|delta/epsilon subdivisions,2X6DE@28221|Deltaproteobacteria,2Z3AK@29|Myxococcales	1224|Proteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_7859813_16	443143.GM18_2642	7.568e-11	68.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_7859813_10	935836.JAEL01000007_gene2898	2.808e-54	200.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,1ZDR0@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	kipR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
LZS2_k127_7859813_6	1033734.CAET01000065_gene2227	3.384e-130	423.0	COG0673@1|root,COG0673@2|Bacteria,1USVA@1239|Firmicutes,4HDVM@91061|Bacilli,1ZQBZ@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_7859813_8	143224.JQMD01000002_gene1709	2.2e-100	334.0	COG3717@1|root,COG3717@2|Bacteria,4NDUV@976|Bacteroidetes,1HY64@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
LZS2_k127_7859813_7	929562.Emtol_1032	4.06e-115	379.0	COG2055@1|root,COG2055@2|Bacteria,4NGVC@976|Bacteroidetes,47MHU@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	1.1.1.130	ko:K08092	ko00040,ko00053,map00040,map00053	-	R02637,R02639	RC00238	ko00000,ko00001,ko01000	-	-	-	Ldh_2
LZS2_k127_7859813_9	309801.trd_1129	4.534e-85	288.0	COG3836@1|root,COG3836@2|Bacteria,2GA3S@200795|Chloroflexi,27Z2Q@189775|Thermomicrobia	189775|Thermomicrobia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
LZS2_k127_7859813_3	383372.Rcas_2455	3.018e-147	473.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS2_k127_7859813_4	266779.Meso_4488	5.1e-142	461.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,43IM6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS2_k127_7859813_2	266779.Meso_4487	7.085e-169	538.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TUWG@28211|Alphaproteobacteria,43R5I@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_7859813_5	1380394.JADL01000001_gene2216	5.915e-141	454.0	COG0601@1|root,COG0601@2|Bacteria,1MWXF@1224|Proteobacteria,2TR7C@28211|Alphaproteobacteria,2JQ7B@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_7859813_1	1380394.JADL01000001_gene2217	1.143e-246	782.0	COG0747@1|root,COG0747@2|Bacteria,1MU3P@1224|Proteobacteria,2TT4M@28211|Alphaproteobacteria,2JQRE@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_7859813_12	1056820.KB900629_gene1723	5.75e-43	166.0	COG2186@1|root,COG2186@2|Bacteria,1RBCJ@1224|Proteobacteria,1SDYA@1236|Gammaproteobacteria,2PP85@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
LZS2_k127_7859813_11	926569.ANT_11820	4.605e-45	190.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
LZS2_k127_7859813_0	1487953.JMKF01000045_gene2756	3.93e-274	890.0	COG0745@1|root,COG0784@1|root,COG2770@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1GHDJ@1117|Cyanobacteria,1H8KY@1150|Oscillatoriales	1117|Cyanobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
LZS2_k127_7859813_14	428125.CLOLEP_02218	7.746e-31	127.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS2_k127_7873722_0	945713.IALB_2978	2.559e-247	771.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
LZS2_k127_7873722_1	555079.Toce_1227	4.306e-199	634.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,42F33@68295|Thermoanaerobacterales	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
LZS2_k127_7873722_5	926550.CLDAP_05520	3.356e-42	169.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_7873722_2	926550.CLDAP_05510	6.541e-133	431.0	COG1215@1|root,COG1215@2|Bacteria,2G8CP@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7873722_4	357808.RoseRS_0520	9.772e-43	180.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2GAA9@200795|Chloroflexi,376WV@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
LZS2_k127_7873722_3	391612.CY0110_15537	1.352e-60	231.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria,1G1I0@1117|Cyanobacteria,3KK8R@43988|Cyanothece	1117|Cyanobacteria	Q	Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Lectin_C
LZS2_k127_7878112_3	926569.ANT_27650	1.106e-20	95.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
LZS2_k127_7878112_2	113355.CM001775_gene1517	1.325e-23	103.0	COG4467@1|root,COG4467@2|Bacteria,1G4QI@1117|Cyanobacteria	1117|Cyanobacteria	L	Involved in initiation control of chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
LZS2_k127_7878112_0	373903.Hore_18200	1.604e-34	149.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,3WAUZ@53433|Halanaerobiales	186801|Clostridia	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
LZS2_k127_7878112_4	981336.F944_02195	3.193e-07	56.0	COG1225@1|root,COG1225@2|Bacteria,1RH4P@1224|Proteobacteria,1SBKN@1236|Gammaproteobacteria,3NM03@468|Moraxellaceae	1236|Gammaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS2_k127_7879016_5	511051.CSE_02410	1.707e-10	71.0	COG1361@1|root,COG3210@1|root,COG4719@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4719@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
LZS2_k127_7879016_4	1123274.KB899424_gene3003	1.27e-11	74.0	COG0457@1|root,COG0457@2|Bacteria,2J5NB@203691|Spirochaetes	203691|Spirochaetes	S	tetratricopeptide repeat	lmp1	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
LZS2_k127_7879016_0	926569.ANT_19030	2.325e-57	206.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
LZS2_k127_7879016_1	357808.RoseRS_3026	5.522e-54	213.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
LZS2_k127_7879016_2	926569.ANT_14090	3.994e-21	100.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
LZS2_k127_7879016_3	926569.ANT_14090	9.496e-16	91.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
LZS2_k127_7879016_6	34839.XP_005401330.1	0.0006503	50.0	KOG4659@1|root,KOG4659@2759|Eukaryota,39S2R@33154|Opisthokonta,3BG22@33208|Metazoa,3CSRC@33213|Bilateria,48ASH@7711|Chordata,491RH@7742|Vertebrata,3JC2B@40674|Mammalia,35IXN@314146|Euarchontoglires,4PY7M@9989|Rodentia	33208|Metazoa	T	Teneurin-1 isoform X1	TENM1	GO:0000902,GO:0001932,GO:0001934,GO:0002376,GO:0003674,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005794,GO:0005856,GO:0005886,GO:0005887,GO:0006355,GO:0006359,GO:0006955,GO:0007155,GO:0007157,GO:0007275,GO:0007399,GO:0008064,GO:0008150,GO:0008201,GO:0008285,GO:0009653,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010562,GO:0010604,GO:0010638,GO:0010646,GO:0010647,GO:0012505,GO:0016020,GO:0016021,GO:0016043,GO:0016363,GO:0016604,GO:0016607,GO:0019219,GO:0019220,GO:0019222,GO:0022008,GO:0022610,GO:0023051,GO:0023056,GO:0030154,GO:0030182,GO:0030832,GO:0030833,GO:0030838,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031334,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031974,GO:0031981,GO:0032268,GO:0032270,GO:0032271,GO:0032273,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032535,GO:0032879,GO:0032880,GO:0032956,GO:0032970,GO:0032989,GO:0033043,GO:0033135,GO:0033138,GO:0033157,GO:0033674,GO:0034399,GO:0042127,GO:0042325,GO:0042327,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043085,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043549,GO:0044087,GO:0044089,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044459,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0046982,GO:0046983,GO:0048468,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050839,GO:0050896,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051222,GO:0051223,GO:0051246,GO:0051247,GO:0051252,GO:0051338,GO:0051347,GO:0051489,GO:0051491,GO:0051493,GO:0051495,GO:0060255,GO:0060341,GO:0060491,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0080090,GO:0090066,GO:0090087,GO:0090316,GO:0097367,GO:0097458,GO:0098609,GO:0098742,GO:0110053,GO:0120025,GO:0120032,GO:0120034,GO:0120035,GO:1901681,GO:1902531,GO:1902533,GO:1902903,GO:1902905,GO:1903506,GO:1903827,GO:1903829,GO:1904951,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	EGF_2,Ten_N,Tox-GHH
LZS2_k127_7899314_1	926569.ANT_23640	4.984e-85	311.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
LZS2_k127_7899314_0	1304880.JAGB01000003_gene1231	3.183e-118	384.0	COG4813@1|root,COG4813@2|Bacteria,1TPZ1@1239|Firmicutes,24EF0@186801|Clostridia	186801|Clostridia	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
LZS2_k127_790817_1	1128421.JAGA01000003_gene3534	1.244e-61	219.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
LZS2_k127_790817_3	357808.RoseRS_4623	2.783e-11	74.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,Peptidase_C39_2,Rhomboid,TPR_16,TPR_19,TPR_8
LZS2_k127_790817_2	1278073.MYSTI_06898	4.29e-19	98.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,42UJ1@68525|delta/epsilon subdivisions,2WR2I@28221|Deltaproteobacteria,2YZRT@29|Myxococcales	28221|Deltaproteobacteria	S	low-complexity proteins	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS2_k127_790817_0	926569.ANT_17130	1.221e-111	366.0	COG4213@1|root,COG4213@2|Bacteria,2G6C4@200795|Chloroflexi	200795|Chloroflexi	G	Periplasmic binding protein domain	-	-	-	ko:K10543,ko:K10546	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	Peripla_BP_4
LZS2_k127_7929039_1	1047013.AQSP01000091_gene649	7.807e-63	238.0	COG2227@1|root,COG3408@1|root,COG2227@2|Bacteria,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,CBM_6,Crystall,Glyco_hydro_64,Methyltransf_11,Methyltransf_23,RicinB_lectin_2,SLH
LZS2_k127_7929039_0	1128421.JAGA01000002_gene569	1.733e-99	333.0	COG1178@1|root,COG1178@2|Bacteria	2|Bacteria	P	thiamine transport	thiP	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	iAPECO1_1312.APECO1_1915,iECIAI1_1343.ECIAI1_0067,iECO103_1326.ECO103_0068,iECO111_1330.ECO111_0069,iECO26_1355.ECO26_0069,iECOK1_1307.ECOK1_0068,iECS88_1305.ECS88_0072,iECSE_1348.ECSE_0067,iECUMN_1333.ECUMN_0068,iPC815.YPO0521,iSF_1195.SF0062,iSFxv_1172.SFxv_0064,iS_1188.S0064,iUMN146_1321.UM146_23130,iUTI89_1310.UTI89_C0075	BPD_transp_1
LZS2_k127_7930736_3	321327.CYA_2481	8.861e-133	433.0	COG3119@1|root,COG3119@2|Bacteria,1G35S@1117|Cyanobacteria,1H28E@1129|Synechococcus	1117|Cyanobacteria	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase,Sulfatase_C
LZS2_k127_7930736_2	886293.Sinac_5883	3.474e-170	548.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_7930736_5	82654.Pse7367_2146	2.882e-78	271.0	COG0682@1|root,COG0682@2|Bacteria,1G23G@1117|Cyanobacteria,1HA8N@1150|Oscillatoriales	1117|Cyanobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS2_k127_7930736_6	1123274.KB899406_gene1124	4.235e-59	229.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF,GAF_2,PAS_3,PAS_9,SSF,SpoIIE
LZS2_k127_7930736_12	179408.Osc7112_6105	1.258e-16	84.0	COG1366@1|root,COG1366@2|Bacteria,1G7NW@1117|Cyanobacteria,1HCQQ@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
LZS2_k127_7930736_11	2055.JNXA01000001_gene2117	1.812e-18	89.0	COG1366@1|root,COG1366@2|Bacteria,2HX78@201174|Actinobacteria,4GEJS@85026|Gordoniaceae	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
LZS2_k127_7930736_10	272123.Anacy_2550	7.38e-27	114.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1GDIS@1117|Cyanobacteria,1HMME@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
LZS2_k127_7930736_0	926569.ANT_04530	0.0	1013.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
LZS2_k127_7930736_4	357808.RoseRS_1730	2.665e-100	342.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,3757Z@32061|Chloroflexia	32061|Chloroflexia	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
LZS2_k127_7930736_8	877414.ATWA01000011_gene2285	2.511e-45	167.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,269BT@186813|unclassified Clostridiales	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS2_k127_7930736_9	35754.JNYJ01000061_gene2366	1.664e-34	138.0	COG0454@1|root,COG0454@2|Bacteria,COG0456@2|Bacteria,2IM18@201174|Actinobacteria,4DEME@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_7930736_7	1487953.JMKF01000075_gene3748	1.442e-45	169.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_7930736_1	338963.Pcar_0575	1.625e-170	543.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41,1.1.1.85	ko:K00030,ko:K00052	ko00020,ko00290,ko00660,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00660,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00432,M00535	R00709,R00994,R04426,R10052	RC00084,RC00114,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS2_k127_7939736_2	926550.CLDAP_04460	1.503e-70	258.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7939736_1	1535287.JP74_08025	8.706e-71	266.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,NB-ARC,cNMP_binding
LZS2_k127_7939736_0	926550.CLDAP_04470	2.429e-85	303.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7944784_2	926550.CLDAP_13470	1.569e-46	172.0	COG2087@1|root,COG2087@2|Bacteria,2G6SV@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cobalbumin biosynthesis protein	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
LZS2_k127_7944784_0	1499967.BAYZ01000104_gene3692	4.807e-112	374.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_7944784_3	1128421.JAGA01000002_gene728	1.691e-33	133.0	2DQ01@1|root,32UN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7944784_4	926569.ANT_18820	1.436e-27	115.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	-	-	-	ko:K06039,ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
LZS2_k127_7944784_1	373994.Riv7116_4517	1.043e-59	217.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,COR,LRR_4,LRR_8,Roc
LZS2_k127_7944784_5	309807.SRU_2047	4.346e-07	54.0	COG3536@1|root,COG3536@2|Bacteria,4PF7B@976|Bacteroidetes,1FK8U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
LZS2_k127_7956096_2	926550.CLDAP_04490	1.034e-31	141.0	COG0823@1|root,COG3103@1|root,COG0823@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	NLPC_P60,Rick_17kDa_Anti,SH3_3
LZS2_k127_7956096_1	926550.CLDAP_20680	6.742e-70	254.0	COG0845@1|root,COG0845@2|Bacteria,2G8HH@200795|Chloroflexi	200795|Chloroflexi	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
LZS2_k127_7956096_3	1128421.JAGA01000002_gene78	2.585e-17	97.0	COG1928@1|root,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
LZS2_k127_7956096_0	357808.RoseRS_1075	1.817e-144	479.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_7968960_2	1380354.JIAN01000008_gene3313	3.374e-81	275.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
LZS2_k127_7968960_0	234267.Acid_2222	3.553e-148	477.0	COG1063@1|root,COG1063@2|Bacteria,3Y6II@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_7968960_4	234267.Acid_1479	1.079e-48	187.0	COG1609@1|root,COG1609@2|Bacteria,3Y6K5@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_7968960_5	743719.PaelaDRAFT_4360	2.618e-10	64.0	COG1331@1|root,COG1331@2|Bacteria,1TQ83@1239|Firmicutes,4HEH5@91061|Bacilli,26S2R@186822|Paenibacillaceae	91061|Bacilli	O	Glycosyl hydrolase	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
LZS2_k127_7968960_1	272558.10174785	9.807e-109	360.0	COG3717@1|root,COG3717@2|Bacteria,1TP4X@1239|Firmicutes,4HBJH@91061|Bacilli,1ZAX5@1386|Bacillus	91061|Bacilli	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
LZS2_k127_7968960_3	760568.Desku_1636	5.445e-58	216.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,261SM@186807|Peptococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02525,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
LZS2_k127_7969136_1	1267533.KB906737_gene1499	1.132e-132	435.0	COG3345@1|root,COG3345@2|Bacteria,3Y6JU@57723|Acidobacteria,2JKCG@204432|Acidobacteriia	204432|Acidobacteriia	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
LZS2_k127_7969136_3	1380391.JIAS01000012_gene3959	6.022e-102	342.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2TS8M@28211|Alphaproteobacteria,2JPSD@204441|Rhodospirillales	204441|Rhodospirillales	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
LZS2_k127_7969136_2	926569.ANT_04030	1.634e-108	360.0	COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS2_k127_7969136_0	926569.ANT_04040	9.438e-161	517.0	COG1653@1|root,COG1653@2|Bacteria,2G82H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10188	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
LZS2_k127_7973927_2	926550.CLDAP_29000	2.329e-93	310.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi	200795|Chloroflexi	L	DNA photolyase domain protein	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
LZS2_k127_7973927_6	926550.CLDAP_28280	5.73e-33	134.0	COG0801@1|root,COG0801@2|Bacteria,2G6YT@200795|Chloroflexi	200795|Chloroflexi	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
LZS2_k127_7973927_3	1521187.JPIM01000030_gene1498	1.942e-87	294.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
LZS2_k127_7973927_5	649638.Trad_2243	1.935e-43	172.0	COG0204@1|root,COG2324@1|root,COG0204@2|Bacteria,COG2324@2|Bacteria,1WI4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM lycopene cyclase domain	-	-	5.5.1.19	ko:K22502	ko00906,map00906	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	Caroten_synth
LZS2_k127_7973927_0	429009.Adeg_1192	3.888e-144	463.0	COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,24GKF@186801|Clostridia,42HT2@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM zinc-binding alcohol dehydrogenase family protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_7973927_4	118161.KB235922_gene3981	8.557e-62	217.0	COG3597@1|root,COG3597@2|Bacteria,1G0MM@1117|Cyanobacteria	1117|Cyanobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,SHOCT
LZS2_k127_7973927_7	316274.Haur_3749	5.634e-30	130.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
LZS2_k127_7973927_1	926550.CLDAP_10300	2.236e-142	461.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS2_k127_7978667_7	1499967.BAYZ01000155_gene664	9.917e-55	213.0	COG0664@1|root,COG1752@1|root,COG4963@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,COG4963@2|Bacteria,2NR14@2323|unclassified Bacteria	2|Bacteria	U	Patatin-like phospholipase	-	-	-	ko:K02282,ko:K07001	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,HTH_Crp_2,Patatin,Response_reg,cNMP_binding
LZS2_k127_7978667_6	324602.Caur_0703	1.317e-83	293.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
LZS2_k127_7978667_9	1382305.AZUC01000046_gene605	6.797e-08	63.0	2EEX1@1|root,338QB@2|Bacteria,1VGA4@1239|Firmicutes,4HPYN@91061|Bacilli,26HTF@186818|Planococcaceae	91061|Bacilli	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
LZS2_k127_7978667_4	926569.ANT_05570	4.295e-92	314.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
LZS2_k127_7978667_8	696747.NIES39_G01210	2.264e-46	194.0	COG0745@1|root,COG2114@1|root,COG2203@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1G0F6@1117|Cyanobacteria,1H7AR@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	cyaC	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HATPase_c,HisKA,Response_reg
LZS2_k127_7978667_5	1313304.CALK_1537	5.083e-88	297.0	COG0467@1|root,COG0467@2|Bacteria	2|Bacteria	T	regulation of circadian rhythm	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
LZS2_k127_7978667_0	713586.KB900536_gene1363	9.339e-248	799.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
LZS2_k127_7978667_3	926550.CLDAP_29920	1.771e-110	372.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
LZS2_k127_7978667_2	926550.CLDAP_29930	3.539e-117	388.0	COG0438@1|root,COG0438@2|Bacteria,2G82Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_7978667_1	926550.CLDAP_30860	7.386e-178	572.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi	200795|Chloroflexi	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
LZS2_k127_7987622_1	179408.Osc7112_5370	4.143e-58	220.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG3290@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,1G09B@1117|Cyanobacteria,1H7T9@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_7987622_3	314230.DSM3645_17520	1.079e-12	75.0	COG1846@1|root,COG1846@2|Bacteria,2IZDD@203682|Planctomycetes	203682|Planctomycetes	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
LZS2_k127_7987622_2	886882.PPSC2_c2414	3.224e-38	160.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,4HG99@91061|Bacilli,26RNQ@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	hlyD3	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS2_k127_7987622_0	1121472.AQWN01000002_gene2114	6.108e-67	241.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,260X3@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_7994163_1	671143.DAMO_1988	5.404e-42	168.0	COG1262@1|root,COG1262@2|Bacteria,2NR8C@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
LZS2_k127_7994163_0	926550.CLDAP_29100	1.74e-202	634.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
LZS2_k127_7996295_1	309801.trd_0263	8.226e-25	118.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi,27XRI@189775|Thermomicrobia	189775|Thermomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS2_k127_7996295_0	926550.CLDAP_12420	1.901e-65	230.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
LZS2_k127_7996295_2	926569.ANT_19400	0.0004828	44.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
LZS2_k127_8000400_2	697284.ERIC2_c24120	0.0005673	46.0	COG3655@1|root,COG3655@2|Bacteria,1TU4I@1239|Firmicutes,4ICRR@91061|Bacilli,26ZYE@186822|Paenibacillaceae	91061|Bacilli	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
LZS2_k127_8000400_0	1121430.JMLG01000002_gene1102	1.161e-52	203.0	28JJB@1|root,2Z9CE@2|Bacteria,1U6BP@1239|Firmicutes,24B0T@186801|Clostridia,261SW@186807|Peptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8000400_1	246194.CHY_1719	1.864e-22	104.0	2A8HA@1|root,30XJD@2|Bacteria,1UPU3@1239|Firmicutes,25HP6@186801|Clostridia,42HMD@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
LZS2_k127_8003085_1	1183438.GKIL_3646	1.533e-79	276.0	COG1215@1|root,COG1215@2|Bacteria,1G1FP@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
LZS2_k127_8003085_0	382464.ABSI01000013_gene1570	1.233e-304	974.0	COG2114@1|root,COG3899@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,46U27@74201|Verrucomicrobia	74201|Verrucomicrobia	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
LZS2_k127_8021102_2	926569.ANT_16170	6.491e-85	284.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS2_k127_8021102_1	1128421.JAGA01000002_gene901	2.418e-95	322.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	adoK	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2683	PfkB
LZS2_k127_8021102_0	926550.CLDAP_17710	1.399e-106	353.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
LZS2_k127_8024846_0	1122611.KB904029_gene5275	1.423e-153	525.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales	201174|Actinobacteria	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
LZS2_k127_8024846_1	1380394.JADL01000009_gene3147	2.312e-140	467.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
LZS2_k127_8024846_3	926550.CLDAP_15590	1.109e-30	129.0	2FKQZ@1|root,30TRG@2|Bacteria,2G9KN@200795|Chloroflexi	200795|Chloroflexi	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
LZS2_k127_8024846_2	208444.JNYY01000009_gene3563	5.284e-52	190.0	COG2746@1|root,COG2746@2|Bacteria,2IC5T@201174|Actinobacteria	201174|Actinobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
LZS2_k127_8034301_0	926569.ANT_11780	1.118e-175	614.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_8034301_1	926569.ANT_11770	1.832e-172	559.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_8034301_2	316274.Haur_0593	1.928e-67	247.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_8034301_3	926550.CLDAP_03610	1.956e-37	149.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Maf family protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
LZS2_k127_8038244_3	926550.CLDAP_08680	9.148e-19	87.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
LZS2_k127_8038244_2	237368.SCABRO_02001	1.447e-27	118.0	COG0839@1|root,COG0839@2|Bacteria,2J0MC@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
LZS2_k127_8038244_1	926550.CLDAP_08700	6.5e-60	211.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
LZS2_k127_8038244_0	926550.CLDAP_08710	8.452e-95	322.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS2_k127_8045866_2	1278309.KB907099_gene2830	6.392e-41	152.0	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,1XRS5@135619|Oceanospirillales	135619|Oceanospirillales	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
LZS2_k127_8045866_1	765420.OSCT_2163	2.733e-65	231.0	COG1922@1|root,COG1922@2|Bacteria,2G6J0@200795|Chloroflexi,375GH@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyl transferase, WecB TagA CpsF family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
LZS2_k127_8045866_0	765420.OSCT_1715	3.403e-96	328.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_8045866_3	1120950.KB892794_gene2314	8.741e-06	49.0	28HGI@1|root,2Z7SC@2|Bacteria,2GKHQ@201174|Actinobacteria,4DPGV@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8047851_2	525904.Tter_2275	1.707e-132	429.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_8047851_1	1499967.BAYZ01000009_gene5357	8.3e-223	710.0	COG0840@1|root,COG2203@1|root,COG0840@2|Bacteria,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	pyp	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,HATPase_c,HisKA,MCPsignal,PAS,PAS_3,dCache_1
LZS2_k127_8047851_0	1499967.BAYZ01000009_gene5356	6.656e-243	764.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_8047851_3	880073.Calab_2556	7.049e-32	125.0	COG3251@1|root,COG3251@2|Bacteria,2NRE2@2323|unclassified Bacteria	2|Bacteria	S	MbtH-like protein	-	-	-	ko:K05375,ko:K09190	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH,YqcI_YcgG
LZS2_k127_8060772_6	1487921.DP68_07195	0.0001643	45.0	COG0745@1|root,COG0745@2|Bacteria,1U3FH@1239|Firmicutes,248BR@186801|Clostridia,36FWV@31979|Clostridiaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_8060772_1	926569.ANT_26550	5.139e-58	213.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
LZS2_k127_8060772_0	439235.Dalk_3003	5.334e-277	873.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS2_k127_8060772_5	439235.Dalk_3004	6.654e-16	79.0	COG2608@1|root,COG2608@2|Bacteria,1PUDD@1224|Proteobacteria,42XJ7@68525|delta/epsilon subdivisions,2WSKI@28221|Deltaproteobacteria,2MP4U@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
LZS2_k127_8060772_4	1521187.JPIM01000159_gene1691	6.062e-17	83.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi,377N3@32061|Chloroflexia	32061|Chloroflexia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
LZS2_k127_8060772_3	547163.BN979_04869	5.485e-28	119.0	COG0607@1|root,COG0607@2|Bacteria,2IIT0@201174|Actinobacteria,239PK@1762|Mycobacteriaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS2_k127_8060772_7	1432055.GLUCORHAEAF1_06240	0.0003772	48.0	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria	1224|Proteobacteria	P	heavy metal transport detoxification protein	merP	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
LZS2_k127_8060772_8	204773.HEAR2415	0.0006611	48.0	COG2823@1|root,COG2823@2|Bacteria,1NIM8@1224|Proteobacteria,2WAK4@28216|Betaproteobacteria,4754N@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
LZS2_k127_8060772_2	926550.CLDAP_14450	5.685e-38	150.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
LZS2_k127_8063084_8	1347087.CBYO010000016_gene2628	7.15e-103	361.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PQQ_2,PQQ_3,Peptidase_S8
LZS2_k127_8063084_2	926569.ANT_10550	7.012e-151	493.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_8063084_5	926550.CLDAP_04410	5.506e-111	376.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_8063084_10	867845.KI911784_gene2299	1.634e-88	297.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi,374VV@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_8063084_7	926550.CLDAP_21330	8.552e-109	364.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
LZS2_k127_8063084_13	682795.AciX8_0871	1.006e-33	143.0	COG0524@1|root,COG0524@2|Bacteria,3Y6KJ@57723|Acidobacteria,2JM4W@204432|Acidobacteriia	204432|Acidobacteriia	H	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS2_k127_8063084_15	670487.Ocepr_0856	3.222e-08	65.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_8063084_6	1307761.L21SP2_1482	6.861e-110	367.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
LZS2_k127_8063084_4	1307761.L21SP2_1483	4.71e-116	378.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
LZS2_k127_8063084_3	1307761.L21SP2_1484	1.796e-149	488.0	COG3639@1|root,COG3639@2|Bacteria,2J6TW@203691|Spirochaetes	203691|Spirochaetes	U	ABC transporter (Permease)	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
LZS2_k127_8063084_14	215803.DB30_1947	1.621e-10	74.0	2DY29@1|root,32V4J@2|Bacteria,1P2QH@1224|Proteobacteria,43F3S@68525|delta/epsilon subdivisions,2X9U6@28221|Deltaproteobacteria,2YV4T@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8063084_0	1128421.JAGA01000002_gene1788	2.946e-178	571.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_8063084_1	357808.RoseRS_0384	1.64e-154	499.0	COG0330@1|root,COG0330@2|Bacteria,2GAIW@200795|Chloroflexi,376FS@32061|Chloroflexia	32061|Chloroflexia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_8063084_12	511051.CSE_03850	4.021e-66	241.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K15770,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,Cu_amine_oxidN1,SBP_bac_8
LZS2_k127_8063084_9	511051.CSE_03860	1.389e-99	336.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	malF	-	-	ko:K02025,ko:K15770,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,SBP_bac_8
LZS2_k127_8063084_11	511051.CSE_03870	1.907e-81	284.0	COG3833@1|root,COG3833@2|Bacteria	2|Bacteria	P	maltose-transporting ATPase activity	malG	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
LZS2_k127_8063084_16	634498.mru_1288	2.192e-05	55.0	COG0639@1|root,arCOG01143@2157|Archaea,2Y3W3@28890|Euryarchaeota,23PN1@183925|Methanobacteria	183925|Methanobacteria	T	Protein phosphatase 2A homologues, catalytic domain.	-	-	3.1.3.16	ko:K06269	ko03015,ko04022,ko04024,ko04113,ko04114,ko04218,ko04261,ko04270,ko04390,ko04510,ko04611,ko04720,ko04728,ko04750,ko04810,ko04910,ko04921,ko04931,ko05031,ko05034,ko05168,ko05205,map03015,map04022,map04024,map04113,map04114,map04218,map04261,map04270,map04390,map04510,map04611,map04720,map04728,map04750,map04810,map04910,map04921,map04931,map05031,map05034,map05168,map05205	-	-	-	ko00000,ko00001,ko01000,ko01009,ko03019,ko03021,ko03041	-	-	-	Metallophos
LZS2_k127_8063671_1	479434.Sthe_0838	6.097e-65	226.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi,27XGA@189775|Thermomicrobia	189775|Thermomicrobia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
LZS2_k127_8063671_5	1173023.KE650771_gene1767	8.506e-14	77.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG4251@2|Bacteria,1GHCI@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_4,Response_reg
LZS2_k127_8063671_4	357808.RoseRS_3289	1.14e-19	93.0	COG2172@1|root,COG2172@2|Bacteria,2GBV4@200795|Chloroflexi,375TN@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
LZS2_k127_8063671_0	926550.CLDAP_18870	4.513e-150	503.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
LZS2_k127_8063671_3	373903.Hore_04500	6.613e-21	104.0	COG1525@1|root,COG4085@1|root,COG1525@2|Bacteria,COG4085@2|Bacteria,1VASF@1239|Firmicutes,24G14@186801|Clostridia,3WANR@53433|Halanaerobiales	186801|Clostridia	L	nucleic acid binding	nucH	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Ada_Zn_binding,SNase
LZS2_k127_8063671_2	311424.DhcVS_1008	7.951e-61	215.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi,34CM3@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
LZS2_k127_8066174_0	497964.CfE428DRAFT_4524	6.195e-46	169.0	COG0454@1|root,COG0456@2|Bacteria,46VJ5@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
LZS2_k127_8066174_1	709986.Deima_3038	2.795e-06	59.0	COG0515@1|root,COG1470@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.2.1.50	ko:K01205,ko:K07004	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07816	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ChW,DUF916,NAGLU,NAGLU_C,NAGLU_N,Ricin_B_lectin
LZS2_k127_8066174_2	755178.Cyan10605_3111	4.701e-05	55.0	COG0515@1|root,COG2959@1|root,COG3103@1|root,COG0515@2|Bacteria,COG2959@2|Bacteria,COG4991@2|Bacteria,1G0B6@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	spkD	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4101,Pkinase,SH3_3
LZS2_k127_8067088_8	880071.Fleli_1198	2.819e-48	186.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS2_k127_8067088_6	656024.FsymDg_0437	1.599e-52	191.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
LZS2_k127_8067088_5	386456.JQKN01000013_gene2982	1.904e-53	198.0	arCOG01788@1|root,arCOG01788@2157|Archaea,2XXVU@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
LZS2_k127_8067088_7	926569.ANT_28790	2.773e-49	179.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
LZS2_k127_8067088_1	926550.CLDAP_27990	2.396e-156	502.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_8067088_2	926569.ANT_28810	2.955e-150	482.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
LZS2_k127_8067088_3	1521187.JPIM01000118_gene809	1.092e-140	460.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi,375AX@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the HMG-CoA reductase family	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
LZS2_k127_8067088_9	1125863.JAFN01000001_gene2345	4.471e-38	158.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS2_k127_8067088_4	1303518.CCALI_02605	2.402e-127	437.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	6.3.2.2	ko:K01919,ko:K03072,ko:K03074,ko:K12257	ko00270,ko00480,ko01100,ko02024,ko03060,ko03070,map00270,map00480,map01100,map02024,map03060,map03070	M00118,M00335	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS2_k127_8067088_10	1122599.AUGR01000015_gene2698	5.116e-36	153.0	COG5549@1|root,COG5549@2|Bacteria,1RIJW@1224|Proteobacteria,1SIG8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
LZS2_k127_8067088_12	388467.A19Y_3285	8.371e-30	133.0	COG2755@1|root,COG2755@2|Bacteria,1G3BA@1117|Cyanobacteria,1H9ZK@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
LZS2_k127_8067088_13	111780.Sta7437_4053	3.433e-15	86.0	COG1605@1|root,COG1605@2|Bacteria,1G8B8@1117|Cyanobacteria,3VKAP@52604|Pleurocapsales	1117|Cyanobacteria	E	Chorismate mutase type II	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	CM_2
LZS2_k127_8067088_11	1041930.Mtc_2367	9.144e-31	132.0	COG1720@1|root,arCOG00761@2157|Archaea,2XYZ5@28890|Euryarchaeota,2N9XJ@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
LZS2_k127_8067088_0	1128421.JAGA01000002_gene390	4.151e-163	534.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_8074052_12	525904.Tter_2008	7.168e-06	48.0	COG1063@1|root,COG1063@2|Bacteria,2NQTM@2323|unclassified Bacteria	2|Bacteria	C	Zinc-binding dehydrogenase	rspB	-	1.1.1.380	ko:K08322	ko00040,ko01100,map00040,map01100	-	R10848	RC00085	ko00000,ko00001,ko01000	-	-	iYO844.BSU12330	ADH_N,ADH_zinc_N
LZS2_k127_8074052_11	448385.sce7136	1.831e-07	55.0	COG1366@1|root,COG1366@2|Bacteria,1PFNC@1224|Proteobacteria,435YR@68525|delta/epsilon subdivisions,2X0FT@28221|Deltaproteobacteria,2Z11Q@29|Myxococcales	28221|Deltaproteobacteria	T	Anti-anti sigma factor protein	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	PAS_4,STAS
LZS2_k127_8074052_6	326427.Cagg_1136	4.189e-62	217.0	COG0652@1|root,COG0652@2|Bacteria,2G69B@200795|Chloroflexi,375JG@32061|Chloroflexia	32061|Chloroflexia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
LZS2_k127_8074052_8	357808.RoseRS_2438	5.968e-45	170.0	COG0652@1|root,COG0652@2|Bacteria,2G8IA@200795|Chloroflexi,375NH@32061|Chloroflexia	32061|Chloroflexia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
LZS2_k127_8074052_5	65071.PYU1_T002180	8.801e-70	244.0	COG0363@1|root,KOG3147@2759|Eukaryota,1MIW6@121069|Pythiales	121069|Pythiales	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosamine_iso
LZS2_k127_8074052_0	383372.Rcas_1852	5.037e-171	551.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
LZS2_k127_8074052_1	357808.RoseRS_2615	1.543e-135	441.0	COG2170@1|root,COG2170@2|Bacteria,2G5NR@200795|Chloroflexi,375BI@32061|Chloroflexia	32061|Chloroflexia	F	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
LZS2_k127_8074052_3	562970.Btus_2368	3.195e-115	382.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,278TC@186823|Alicyclobacillaceae	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS2_k127_8074052_4	926550.CLDAP_28680	5.909e-100	340.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	SH3_3,SH3_4
LZS2_k127_8074052_13	110319.CF8_1244	8.388e-06	56.0	COG2887@1|root,COG2887@2|Bacteria,2I4PW@201174|Actinobacteria,4DWXV@85009|Propionibacteriales	201174|Actinobacteria	F	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
LZS2_k127_8074052_2	324602.Caur_1534	3.265e-125	410.0	COG0263@1|root,COG0263@2|Bacteria,2G67X@200795|Chloroflexi,3757K@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
LZS2_k127_8074052_7	479434.Sthe_1975	6.766e-49	197.0	COG2730@1|root,COG2730@2|Bacteria,2GBH8@200795|Chloroflexi,27Y4J@189775|Thermomicrobia	189775|Thermomicrobia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
LZS2_k127_8074052_9	1239962.C943_03877	2.795e-37	161.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
LZS2_k127_8074052_10	1379281.AVAG01000068_gene681	1.928e-19	91.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,42T5Y@68525|delta/epsilon subdivisions,2WNT6@28221|Deltaproteobacteria,2MAZR@213115|Desulfovibrionales	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS2_k127_8075461_5	1122164.JHWF01000043_gene1435	1.654e-57	203.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,1JEMH@118969|Legionellales	118969|Legionellales	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
LZS2_k127_8075461_9	357808.RoseRS_3186	1.589e-35	147.0	2ECS5@1|root,336PT@2|Bacteria,2G96H@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
LZS2_k127_8075461_0	357808.RoseRS_3184	1.862e-144	465.0	COG0714@1|root,COG0714@2|Bacteria,2G8BI@200795|Chloroflexi,377XH@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_8075461_3	357808.RoseRS_3183	1.813e-125	414.0	COG1721@1|root,COG1721@2|Bacteria,2G7JJ@200795|Chloroflexi	200795|Chloroflexi	M	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS2_k127_8075461_8	1227352.C173_08671	6.915e-43	168.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TQKE@1239|Firmicutes,4HMG5@91061|Bacilli,26QGN@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,GyrI-like,HTH_18
LZS2_k127_8075461_10	386456.JQKN01000002_gene2689	1.097e-28	121.0	28H67@1|root,2N567@2157|Archaea,2Y3I0@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2
LZS2_k127_8075461_4	694430.Natoc_0115	3.497e-119	396.0	COG2311@1|root,arCOG06418@2157|Archaea,2XUST@28890|Euryarchaeota,23U4C@183963|Halobacteria	183963|Halobacteria	S	membrane	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
LZS2_k127_8075461_6	1227352.C173_27002	4.763e-44	165.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,4HRFR@91061|Bacilli,2753A@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
LZS2_k127_8075461_1	986075.CathTA2_2383	1.786e-137	447.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli	91061|Bacilli	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS2_k127_8075461_2	1125863.JAFN01000001_gene332	8.377e-137	449.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_8075461_7	1121422.AUMW01000017_gene1972	6.325e-43	164.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,261KY@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
LZS2_k127_8078694_0	272558.10173260	9.246e-44	169.0	COG1078@1|root,COG1078@2|Bacteria,1VHDD@1239|Firmicutes,4HPCC@91061|Bacilli,1ZCY7@1386|Bacillus	91061|Bacilli	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
LZS2_k127_8078694_4	926550.CLDAP_21830	6.012e-09	67.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8078694_1	926569.ANT_22530	7.57e-42	164.0	COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
LZS2_k127_8078694_2	1121405.dsmv_0915	1.674e-35	140.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,2MKE0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_8078694_3	926550.CLDAP_10530	2.783e-30	132.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_8084862_6	768704.Desmer_2505	3.027e-44	170.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,2623D@186807|Peptococcaceae	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
LZS2_k127_8084862_3	926550.CLDAP_06860	4.157e-73	252.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi	200795|Chloroflexi	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
LZS2_k127_8084862_8	926550.CLDAP_06850	2.485e-40	153.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
LZS2_k127_8084862_4	926550.CLDAP_06830	1.082e-67	238.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS2_k127_8084862_0	926550.CLDAP_06820	2.151e-203	646.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
LZS2_k127_8084862_12	472759.Nhal_1189	1.234e-09	72.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1WX32@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
LZS2_k127_8084862_1	1047013.AQSP01000098_gene2566	1.329e-187	593.0	COG0162@1|root,COG0162@2|Bacteria,2NNMR@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
LZS2_k127_8084862_7	1267535.KB906767_gene735	2.006e-41	164.0	COG1073@1|root,COG1073@2|Bacteria,3Y5TG@57723|Acidobacteria,2JNP5@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8084862_5	1499967.BAYZ01000090_gene4936	5.638e-47	194.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_8084862_9	316274.Haur_2143	1.381e-31	144.0	COG0784@1|root,COG1620@1|root,COG4251@1|root,COG0784@2|Bacteria,COG1620@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.1.1.80,3.1.1.61	ko:K03303,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	2.A.14	-	-	HATPase_c,HisKA,Lactate_perm,Response_reg
LZS2_k127_8084862_2	1449126.JQKL01000071_gene3639	3.636e-141	477.0	COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1UJJI@1239|Firmicutes,25F4M@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
LZS2_k127_8084862_10	1499967.BAYZ01000095_gene4168	8.52e-19	94.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
LZS2_k127_8090760_1	1123508.JH636446_gene6369	2.147e-121	420.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_8090760_2	1380394.JADL01000004_gene5843	4.738e-73	253.0	COG0745@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,1QWDW@1224|Proteobacteria,2UH6A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_8090760_4	1380394.JADL01000004_gene5842	1.965e-55	220.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2JUYZ@204441|Rhodospirillales	204441|Rhodospirillales	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_8090760_7	926569.ANT_11830	1.143e-31	144.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
LZS2_k127_8090760_6	1244869.H261_00340	3.542e-36	158.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2JPBA@204441|Rhodospirillales	204441|Rhodospirillales	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS
LZS2_k127_8090760_3	1123326.JFBL01000003_gene1903	1.868e-59	218.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,42MU0@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
LZS2_k127_8090760_5	1380394.JADL01000004_gene5842	9.018e-55	220.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2JUYZ@204441|Rhodospirillales	204441|Rhodospirillales	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_8090760_0	1499967.BAYZ01000108_gene2206	2.032e-135	468.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
LZS2_k127_8090760_8	1123508.JH636439_gene1391	2.017e-07	53.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_8093349_0	926550.CLDAP_00790	2.554e-96	357.0	COG1361@1|root,COG3898@1|root,COG1361@2|Bacteria,COG3898@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS2_k127_8122457_8	1133849.O3I_041585	8.537e-19	96.0	28HGI@1|root,2Z7SC@2|Bacteria,2GKHQ@201174|Actinobacteria,4FV04@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8122457_0	1499967.BAYZ01000151_gene1666	1.29e-257	807.0	COG1132@1|root,COG1132@2|Bacteria,2NNP8@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_8122457_1	1499967.BAYZ01000151_gene1665	1.835e-244	767.0	COG1132@1|root,COG1132@2|Bacteria,2NP2M@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter transmembrane region	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_8122457_6	926550.CLDAP_04490	1.931e-26	124.0	COG0823@1|root,COG3103@1|root,COG0823@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	NLPC_P60,Rick_17kDa_Anti,SH3_3
LZS2_k127_8122457_5	765420.OSCT_2271	3.123e-40	168.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G8HH@200795|Chloroflexi	200795|Chloroflexi	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
LZS2_k127_8122457_3	765420.OSCT_0805	3.349e-100	341.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi,37660@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_8122457_4	292459.STH976	4.16e-88	298.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_8122457_2	383372.Rcas_2537	7.557e-208	673.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_8122457_7	1123288.SOV_3c05790	1.539e-22	98.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_8133344_8	118166.JH976537_gene1470	9.748e-09	66.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1HA36@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7
LZS2_k127_8133344_5	449447.MAE_46660	3.943e-38	160.0	COG4928@1|root,COG4928@2|Bacteria,1G0KU@1117|Cyanobacteria	1117|Cyanobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
LZS2_k127_8133344_6	479434.Sthe_3270	3.163e-20	106.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2G9C0@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8133344_7	1218173.BALCAV_0221760	2.323e-11	77.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,1ZBDE@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S41A family	ctpB	GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
LZS2_k127_8133344_4	927677.ALVU02000001_gene1596	9.791e-48	174.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria	1117|Cyanobacteria	J	translation initiation inhibitor, yjgF family	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
LZS2_k127_8133344_2	383372.Rcas_1483	7.244e-62	223.0	COG2267@1|root,COG2267@2|Bacteria,2GBMR@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_8133344_1	324602.Caur_1720	2.142e-88	301.0	COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi,376FG@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS2_k127_8133344_0	926569.ANT_08900	1.434e-254	821.0	COG0642@1|root,COG0784@1|root,COG1879@1|root,COG2207@1|root,COG0784@2|Bacteria,COG1879@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	4.2.3.1	ko:K01733,ko:K10439	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,ko02010,ko02030,map00260,map00750,map01100,map01110,map01120,map01230,map02010,map02030	M00018,M00212	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	HATPase_c,HTH_18,HisKA,Peripla_BP_3,Peripla_BP_4,Response_reg
LZS2_k127_8133344_3	1499967.BAYZ01000139_gene126	7.821e-58	213.0	COG0407@1|root,COG0407@2|Bacteria,2NPXG@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
LZS2_k127_8133883_1	926569.ANT_25010	6.232e-200	633.0	COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi	200795|Chloroflexi	H	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,LAM_C,Radical_SAM
LZS2_k127_8133883_2	324925.Ppha_1220	2.231e-68	250.0	COG1357@1|root,COG1357@2|Bacteria,1FEKU@1090|Chlorobi	1090|Chlorobi	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,TIR_2
LZS2_k127_8133883_0	1382306.JNIM01000001_gene1307	4.337e-263	822.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
LZS2_k127_8133883_3	926569.ANT_19800	2.864e-54	199.0	COG0210@1|root,COG0210@2|Bacteria,2G7VU@200795|Chloroflexi	200795|Chloroflexi	F	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8142078_4	1121930.AQXG01000010_gene3108	3.55e-05	46.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS2_k127_8142078_0	1356854.N007_03230	7.726e-150	484.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS2_k127_8142078_1	926550.CLDAP_06710	1.161e-121	405.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS2_k127_8142078_3	111781.Lepto7376_1714	2.331e-19	89.0	COG2501@1|root,COG2501@2|Bacteria	2|Bacteria	S	S4 domain	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
LZS2_k127_8142078_2	357808.RoseRS_0493	1.912e-38	156.0	COG1651@1|root,COG4243@1|root,COG1651@2|Bacteria,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,3764Y@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
LZS2_k127_8142079_4	1121930.AQXG01000010_gene3108	3.55e-05	46.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS2_k127_8142079_2	1123236.KB899376_gene804	5.499e-13	76.0	COG1597@1|root,COG2453@1|root,COG1597@2|Bacteria,COG2453@2|Bacteria,1QSUD@1224|Proteobacteria,1RQAC@1236|Gammaproteobacteria,463ZJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	IT	Diacylglycerol kinase catalytic domain (presumed)	ynbD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	DAGK_cat,DSPc,PAP2_3
LZS2_k127_8142079_0	56780.SYN_00532	4.377e-214	672.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,2MQAM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS2_k127_8142079_3	331636.G5O_0559	7.44e-08	61.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	yccF	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	HTH_psq,SEC-C,TPR_19
LZS2_k127_8142079_5	1144275.COCOR_01921	0.0001621	46.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2WMKB@28221|Deltaproteobacteria,2YXV7@29|Myxococcales	28221|Deltaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
LZS2_k127_8142079_1	1123508.JH636439_gene1853	7.681e-126	424.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_8145737_2	243090.RB5820	1.993e-26	109.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
LZS2_k127_8145737_0	497964.CfE428DRAFT_0337	8.321e-106	350.0	COG3618@1|root,COG3618@2|Bacteria,46SN7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
LZS2_k127_8145737_1	1236514.BAKL01000100_gene5186	3.079e-92	313.0	COG1063@1|root,COG1063@2|Bacteria,4NHCK@976|Bacteroidetes,2FM1Q@200643|Bacteroidia,4AMVF@815|Bacteroidaceae	976|Bacteroidetes	E	Psort location Cytoplasmic, score 9.97	yjmD_1	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_8155031_1	484770.UFO1_1182	3.828e-82	281.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_8155031_0	357808.RoseRS_1075	3.774e-83	288.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_8156929_0	1200792.AKYF01000018_gene5878	8.183e-06	58.0	COG3291@1|root,COG3291@2|Bacteria,1TSRU@1239|Firmicutes,4HTK3@91061|Bacilli,26VP6@186822|Paenibacillaceae	91061|Bacilli	S	Peptidase family M9 N-terminal	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	PKD,PPC,Peptidase_M9,Peptidase_M9_N
LZS2_k127_8156929_1	858215.Thexy_1730	0.0009347	51.0	COG3693@1|root,COG5492@1|root,COG3693@2|Bacteria,COG5492@2|Bacteria,1UHTC@1239|Firmicutes,248KD@186801|Clostridia,42FVN@68295|Thermoanaerobacterales	186801|Clostridia	G	SMART Glycoside hydrolase, family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM9_1,CBM_4_9,Glyco_hydro_10,Polysacc_deac_1,SLH
LZS2_k127_8161554_1	926550.CLDAP_00350	5.287e-158	517.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
LZS2_k127_8161554_9	926550.CLDAP_06550	1.123e-40	169.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
LZS2_k127_8161554_6	926569.ANT_01810	1.118e-84	291.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_8161554_5	717605.Theco_2601	5.51e-116	387.0	COG0524@1|root,COG0524@2|Bacteria,1TT7Y@1239|Firmicutes,4HC0B@91061|Bacilli,26U8T@186822|Paenibacillaceae	91061|Bacilli	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS2_k127_8161554_7	1128421.JAGA01000002_gene16	3.687e-70	246.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
LZS2_k127_8161554_11	926550.CLDAP_22180	1.727e-20	104.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_8161554_15	1499683.CCFF01000014_gene3784	1.483e-06	60.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,36FZK@31979|Clostridiaceae	186801|Clostridia	M	family 25	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
LZS2_k127_8161554_14	637905.SVI_1094	4.307e-11	75.0	COG3291@1|root,COG3291@2|Bacteria,1PDUK@1224|Proteobacteria,1S8QS@1236|Gammaproteobacteria,2Q8NA@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,PPC,Peptidase_M43
LZS2_k127_8161554_3	937777.Deipe_1849	2.779e-147	473.0	COG0451@1|root,COG0451@2|Bacteria,1WM05@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS2_k127_8161554_2	479434.Sthe_1850	2.112e-155	521.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi,27XPG@189775|Thermomicrobia	189775|Thermomicrobia	L	Rad50 zinc hook motif	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
LZS2_k127_8161554_4	926550.CLDAP_34690	2.476e-135	439.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS2_k127_8161554_8	671143.DAMO_1988	3.571e-51	194.0	COG1262@1|root,COG1262@2|Bacteria,2NR8C@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
LZS2_k127_8161554_10	1128421.JAGA01000002_gene1413	3.447e-37	151.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc
LZS2_k127_8161554_0	589865.DaAHT2_1709	4.64e-165	533.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MIKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
LZS2_k127_8161554_12	756067.MicvaDRAFT_4446	4.086e-20	93.0	COG5439@1|root,COG5439@2|Bacteria,1G7UR@1117|Cyanobacteria,1HC99@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG5439 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8165778_8	383372.Rcas_3975	5.406e-17	82.0	COG0673@1|root,COG0673@2|Bacteria,2G6Y0@200795|Chloroflexi,376NR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_8165778_1	1521187.JPIM01000041_gene557	1.883e-134	437.0	COG0399@1|root,COG0399@2|Bacteria,2G5QG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_8165778_3	926550.CLDAP_36230	9.775e-66	230.0	COG0110@1|root,COG0110@2|Bacteria,2G7B9@200795|Chloroflexi	200795|Chloroflexi	S	PFAM transferase hexapeptide repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
LZS2_k127_8165778_5	926569.ANT_06280	9.834e-37	144.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	DUF4388,HTH_24,MarR_2
LZS2_k127_8165778_6	1121403.AUCV01000013_gene3976	2.344e-35	143.0	COG2199@1|root,COG3706@2|Bacteria,1QWNG@1224|Proteobacteria,42SDQ@68525|delta/epsilon subdivisions,2WP1N@28221|Deltaproteobacteria,2MK84@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
LZS2_k127_8165778_10	1123508.JH636439_gene1302	5.045e-12	80.0	COG3920@1|root,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,PAS,PAS_9
LZS2_k127_8165778_4	1499967.BAYZ01000015_gene6576	2.283e-53	216.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	MA20_35625	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Peripla_BP_3
LZS2_k127_8165778_7	880072.Desac_0096	4.807e-20	107.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_8,PAS_9,Response_reg,SBP_bac_3
LZS2_k127_8165778_9	243231.GSU2534	1.403e-13	85.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,42ZT5@68525|delta/epsilon subdivisions,2WUU8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response receiver sensor diguanylate cyclase, PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS2_k127_8165778_2	926550.CLDAP_35490	2.493e-91	314.0	COG2730@1|root,COG3103@1|root,COG2730@2|Bacteria,COG4991@2|Bacteria,2G7Y2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
LZS2_k127_8165778_0	926550.CLDAP_19740	3.615e-281	884.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi	200795|Chloroflexi	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
LZS2_k127_8171351_5	765420.OSCT_1170	8.948e-62	215.0	COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like,PBP_like_2
LZS2_k127_8171351_2	765420.OSCT_1171	3.529e-126	411.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi,375B0@32061|Chloroflexia	32061|Chloroflexia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS2_k127_8171351_3	316274.Haur_3997	1.093e-76	283.0	COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like,PBP_like_2
LZS2_k127_8171351_1	1128421.JAGA01000002_gene1717	1.364e-126	431.0	COG0581@1|root,COG0581@2|Bacteria,2NPJS@2323|unclassified Bacteria	2|Bacteria	P	phosphate transport system permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS2_k127_8171351_0	926569.ANT_27750	4.928e-128	413.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
LZS2_k127_8171351_4	926569.ANT_27760	4.935e-62	220.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi	200795|Chloroflexi	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
LZS2_k127_8187616_3	326427.Cagg_3564	1.602e-99	327.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi,3758U@32061|Chloroflexia	32061|Chloroflexia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS2_k127_8187616_0	357808.RoseRS_0489	3.656e-184	583.0	COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi,37571@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
LZS2_k127_8187616_4	1120950.KB892749_gene3367	2.51e-86	300.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DN4V@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	ugpC	-	3.6.3.20	ko:K05816	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.3	-	-	ABC_tran,TOBE_2
LZS2_k127_8187616_6	160799.PBOR_05345	4.041e-59	213.0	COG1011@1|root,COG1011@2|Bacteria,1TRQ6@1239|Firmicutes,4HKAS@91061|Bacilli,26UF1@186822|Paenibacillaceae	91061|Bacilli	S	2-haloalkanoic acid dehalogenase	yfnB	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS2_k127_8187616_8	583355.Caka_2946	9.704e-46	169.0	COG0139@1|root,COG0139@2|Bacteria,46SZA@74201|Verrucomicrobia,3K7YM@414999|Opitutae	414999|Opitutae	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
LZS2_k127_8187616_1	331678.Cphamn1_2223	3.023e-119	389.0	COG0040@1|root,COG0040@2|Bacteria,1FDU2@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
LZS2_k127_8187616_9	696281.Desru_1964	1.005e-31	141.0	2DQ2F@1|root,334G7@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14337	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	-
LZS2_k127_8187616_10	1499967.BAYZ01000100_gene3469	2.192e-09	58.0	COG4034@1|root,COG4034@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF1152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1152
LZS2_k127_8187616_5	234267.Acid_5780	1.595e-80	307.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
LZS2_k127_8187616_7	1121451.DESAM_22601	5.881e-55	223.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2M93E@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS2_k127_8187616_2	926550.CLDAP_39300	1.038e-113	395.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
LZS2_k127_8189841_0	1499967.BAYZ01000160_gene414	1.207e-117	388.0	COG1524@1|root,COG1524@2|Bacteria,2NQ0M@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_8189841_1	251221.35211649	2.723e-66	229.0	COG1051@1|root,COG1051@2|Bacteria,1GEI3@1117|Cyanobacteria	1117|Cyanobacteria	F	NUDIX domain	-	-	-	ko:K03207	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
LZS2_k127_8189841_2	1499967.BAYZ01000157_gene603	2.607e-60	236.0	COG2203@1|root,COG2208@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	3.1.3.3	ko:K07315,ko:K17763	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,STAS
LZS2_k127_8189841_3	926569.ANT_12750	1.245e-54	196.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
LZS2_k127_8190512_7	886293.Sinac_7157	1.56e-35	143.0	COG1528@1|root,COG1528@2|Bacteria	2|Bacteria	P	ferric iron binding	ftn	GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771	1.16.3.1,1.16.3.2	ko:K02217,ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
LZS2_k127_8190512_4	1450694.BTS2_2423	7.296e-79	275.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,1ZC8R@1386|Bacillus	91061|Bacilli	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
LZS2_k127_8190512_6	926569.ANT_06220	1.016e-37	146.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS2_k127_8190512_2	926550.CLDAP_27330	1.958e-107	359.0	COG1609@1|root,COG1609@2|Bacteria,2G6BD@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
LZS2_k127_8190512_0	1499967.BAYZ01000077_gene870	1.136e-203	643.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_Isome,Fucose_iso_C
LZS2_k127_8190512_3	1499967.BAYZ01000076_gene780	8.823e-103	343.0	COG0191@1|root,COG0191@2|Bacteria	2|Bacteria	G	fructose-bisphosphate aldolase activity	-	-	4.1.2.13,4.1.2.40	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01069,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
LZS2_k127_8190512_1	1499967.BAYZ01000172_gene5770	1.272e-125	411.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
LZS2_k127_819220_2	439235.Dalk_3003	1.336e-87	295.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS2_k127_819220_3	357808.RoseRS_2962	2.022e-40	154.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi,375ZD@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS2_k127_819220_7	96561.Dole_1877	3.271e-19	89.0	COG2608@1|root,COG2608@2|Bacteria,1PUDD@1224|Proteobacteria,42XJ7@68525|delta/epsilon subdivisions,2WSKI@28221|Deltaproteobacteria,2MP4U@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
LZS2_k127_819220_6	926569.ANT_12610	7.182e-28	114.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
LZS2_k127_819220_4	326423.RBAM_015590	3.649e-40	160.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,1ZCYC@1386|Bacillus	91061|Bacilli	T	phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS2_k127_819220_1	926550.CLDAP_01880	1.03e-140	456.0	COG3664@1|root,COG3664@2|Bacteria,2G82D@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_819220_5	926550.CLDAP_01890	3.174e-33	143.0	COG0834@1|root,COG0834@2|Bacteria,2G8WT@200795|Chloroflexi	200795|Chloroflexi	ET	extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
LZS2_k127_819220_0	443143.GM18_0045	3.008e-155	492.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PCA@68525|delta/epsilon subdivisions,2X9UH@28221|Deltaproteobacteria,43V4E@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Glucose dehydrogenase C-terminus	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_8192741_0	1185876.BN8_05371	1.699e-59	214.0	COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,47M1F@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_8192741_2	671143.DAMO_0620	5.808e-32	130.0	2EA1Q@1|root,33470@2|Bacteria	2|Bacteria	-	-	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxD
LZS2_k127_8192741_1	1279009.ADICEAN_04189	2.16e-49	181.0	COG1215@1|root,COG1215@2|Bacteria,4NEK9@976|Bacteroidetes,47MJK@768503|Cytophagia	976|Bacteroidetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_8202039_1	357808.RoseRS_1077	1.305e-30	130.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi,376ZZ@32061|Chloroflexia	32061|Chloroflexia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS2_k127_8202039_0	1541065.JRFE01000012_gene2450	2.278e-35	148.0	COG4447@1|root,COG4447@2|Bacteria,1G2KP@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
LZS2_k127_8202039_2	742738.HMPREF9460_02584	1.138e-12	70.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,2493N@186801|Clostridia,26BC7@186813|unclassified Clostridiales	186801|Clostridia	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_8226552_1	926569.ANT_04070	1.565e-79	273.0	COG1349@1|root,COG1349@2|Bacteria,2G6FT@200795|Chloroflexi	200795|Chloroflexi	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
LZS2_k127_8226552_0	926569.ANT_04060	5.836e-175	553.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS2_k127_8226552_2	926569.ANT_04050	3.871e-12	69.0	COG2222@1|root,COG2222@2|Bacteria,2G66K@200795|Chloroflexi	200795|Chloroflexi	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
LZS2_k127_8293486_0	926569.ANT_20580	8.602e-150	485.0	COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi	200795|Chloroflexi	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
LZS2_k127_8293486_1	926550.CLDAP_18020	1.6e-18	86.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi	200795|Chloroflexi	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
LZS2_k127_8293702_1	926569.ANT_10420	8.356e-37	145.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS2_k127_8293702_3	913865.DOT_4202	3.92e-28	120.0	COG0839@1|root,COG0839@2|Bacteria,1VAQI@1239|Firmicutes,24NAC@186801|Clostridia,262J1@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
LZS2_k127_8293702_2	383372.Rcas_2095	3.966e-30	124.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi,375VH@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
LZS2_k127_8293702_0	926550.CLDAP_08820	2.054e-159	529.0	COG1009@1|root,COG1009@2|Bacteria,2G5XJ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
LZS2_k127_8293702_4	643648.Slip_0258	9.189e-16	80.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	ndhD	-	1.6.5.3	ko:K00342,ko:K05575	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iJN678.ndhD2	Oxidored_q5_N,Proton_antipo_M
LZS2_k127_83451_0	1128421.JAGA01000002_gene1086	1.997e-104	344.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	yicI	GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
LZS2_k127_83451_1	926550.CLDAP_09300	1.786e-75	264.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
LZS2_k127_83451_3	562970.Btus_2604	1.248e-71	252.0	COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,27AT7@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	fabL	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS2_k127_83451_4	926550.CLDAP_20990	1.308e-63	241.0	COG0515@1|root,COG0515@2|Bacteria,2G8NP@200795|Chloroflexi	200795|Chloroflexi	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DZR,Pkinase
LZS2_k127_83451_2	765420.OSCT_1200	1.589e-74	281.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_35,CHAT,DM13,MarR_2,TIR_2,WD40
LZS2_k127_83451_5	926550.CLDAP_07350	3.992e-39	157.0	COG0454@1|root,COG0456@2|Bacteria,2G9KU@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_83451_6	177439.DP0703	9.684e-07	56.0	COG3415@1|root,COG3415@2|Bacteria,1NIF7@1224|Proteobacteria,433PT@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29
LZS2_k127_8348337_1	1329516.JPST01000052_gene918	6.393e-68	243.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,27AY6@186824|Thermoactinomycetaceae	91061|Bacilli	S	ABC transporter C-terminal domain	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS2_k127_8348337_3	926550.CLDAP_37310	1.764e-08	61.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2
LZS2_k127_8348337_0	1121430.JMLG01000030_gene1612	3.968e-147	484.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,260G0@186807|Peptococcaceae	186801|Clostridia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
LZS2_k127_8348337_2	698758.AXY_23920	2.189e-10	62.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli	91061|Bacilli	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
LZS2_k127_8354945_2	1128421.JAGA01000002_gene1478	9.343e-33	128.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	rhaS	-	-	ko:K02058,ko:K10559	ko02010,map02010	M00220,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.9	-	-	Peripla_BP_4
LZS2_k127_8354945_0	326427.Cagg_3315	4.199e-199	627.0	COG4806@1|root,COG4806@2|Bacteria,2GAHK@200795|Chloroflexi,37666@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the rhamnose isomerase family	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
LZS2_k127_8354945_1	1304880.JAGB01000001_gene463	4.201e-154	501.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	rhaB	-	2.7.1.5,2.7.1.51	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014,R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
LZS2_k127_8354945_3	926550.CLDAP_12710	5.438e-09	59.0	COG3347@1|root,COG3347@2|Bacteria	2|Bacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
LZS2_k127_8365731_1	383372.Rcas_3910	2.184e-18	91.0	COG0664@1|root,COG0664@2|Bacteria,2GBTI@200795|Chloroflexi,375RB@32061|Chloroflexia	32061|Chloroflexia	T	PFAM cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
LZS2_k127_8365731_0	768066.HELO_2692	6.372e-52	195.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XJJ8@135619|Oceanospirillales	135619|Oceanospirillales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
LZS2_k127_8369109_9	913325.N799_12710	4.249e-31	125.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria,1X375@135614|Xanthomonadales	135614|Xanthomonadales	L	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,Helicase_C,ResIII
LZS2_k127_8369109_3	324602.Caur_1283	1.075e-99	338.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_8369109_1	926550.CLDAP_04540	6.333e-152	495.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
LZS2_k127_8369109_8	324602.Caur_0206	4.793e-49	185.0	COG3346@1|root,COG3346@2|Bacteria,2G8X9@200795|Chloroflexi,377E5@32061|Chloroflexia	32061|Chloroflexia	S	SURF1 family	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
LZS2_k127_8369109_0	926569.ANT_20890	3.945e-192	617.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_8369109_4	517418.Ctha_0151	3.048e-99	338.0	COG0205@1|root,COG0205@2|Bacteria,1FDFG@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS2_k127_8369109_5	357808.RoseRS_3212	9.653e-88	297.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
LZS2_k127_8369109_2	484770.UFO1_1183	1.447e-123	425.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_8369109_6	1408433.JHXV01000027_gene3706	1.459e-55	205.0	COG0702@1|root,COG0702@2|Bacteria,4NFUX@976|Bacteroidetes	976|Bacteroidetes	GM	SPTR NmrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
LZS2_k127_8369109_10	383372.Rcas_2537	5.898e-07	53.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_8369109_7	1499967.BAYZ01000182_gene4446	9.45e-53	192.0	COG1816@1|root,COG1816@2|Bacteria,2NR0J@2323|unclassified Bacteria	2|Bacteria	F	Adenosine/AMP deaminase	add	GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.4.2,3.5.4.4,3.5.4.40	ko:K01488,ko:K18286,ko:K21053	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01244,R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
LZS2_k127_8379801_5	118161.KB235922_gene5081	4.627e-24	106.0	COG0816@1|root,COG0816@2|Bacteria,1G5R5@1117|Cyanobacteria,3VJUT@52604|Pleurocapsales	1117|Cyanobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
LZS2_k127_8379801_4	326427.Cagg_3034	2.097e-24	107.0	COG2172@1|root,COG2172@2|Bacteria,2GBN7@200795|Chloroflexi,375NT@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
LZS2_k127_8379801_6	1033732.CAHI01000015_gene411	1.748e-07	65.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,2FNIT@200643|Bacteroidia	976|Bacteroidetes	T	PAS domain S-box protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_8,PAS_9,Response_reg
LZS2_k127_8379801_2	479434.Sthe_3347	1.649e-58	231.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
LZS2_k127_8379801_1	1449357.JQLK01000001_gene112	1.02e-63	225.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_8379801_0	118168.MC7420_5151	8.45e-153	508.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1H9EM@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	GAF,GAF_2,HATPase_c,HisKA,MASE1,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_8379801_3	756067.MicvaDRAFT_4926	3.695e-52	192.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G0AZ@1117|Cyanobacteria,1H7MZ@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_838050_0	1033802.SSPSH_000021	4.672e-286	894.0	COG1002@1|root,COG1002@2|Bacteria,1MWRH@1224|Proteobacteria,1RRRA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Type II restriction enzyme, methylase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_838050_8	1173024.KI912148_gene2616	2.037e-52	197.0	COG1413@1|root,COG1413@2|Bacteria,1G6P1@1117|Cyanobacteria	1117|Cyanobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_PBS
LZS2_k127_838050_3	926550.CLDAP_31360	9.479e-100	339.0	2DZNW@1|root,32VEY@2|Bacteria,2G8XI@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_838050_6	926550.CLDAP_31370	1.084e-67	241.0	COG1216@1|root,COG1216@2|Bacteria,2G8DR@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
LZS2_k127_838050_7	926550.CLDAP_31380	1.214e-65	233.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
LZS2_k127_838050_9	926550.CLDAP_36380	9.41e-45	169.0	COG1544@1|root,COG1544@2|Bacteria,2G6Z4@200795|Chloroflexi	200795|Chloroflexi	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
LZS2_k127_838050_10	243164.DET1458	2.452e-43	166.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi,34CXG@301297|Dehalococcoidia	301297|Dehalococcoidia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_838050_11	868595.Desca_1183	1.656e-25	109.0	COG1430@1|root,COG1430@2|Bacteria,1VF55@1239|Firmicutes,24QZ4@186801|Clostridia,262WZ@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
LZS2_k127_838050_4	479434.Sthe_0521	1.878e-78	272.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi,27XSY@189775|Thermomicrobia	189775|Thermomicrobia	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS2_k127_838050_5	316274.Haur_4614	1.203e-72	257.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi,3755T@32061|Chloroflexia	32061|Chloroflexia	U	PFAM type II secretion system protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS2_k127_838050_1	309801.trd_1011	7.871e-206	649.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS2_k127_838050_2	1128421.JAGA01000002_gene595	2.115e-108	364.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2NR3E@2323|unclassified Bacteria	2|Bacteria	D	AAA domain	flpE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA,Response_reg
LZS2_k127_8413628_1	765420.OSCT_0039	7.675e-129	422.0	COG0654@1|root,COG0654@2|Bacteria,2G7PK@200795|Chloroflexi	200795|Chloroflexi	CH	Lycopene cyclase protein	-	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
LZS2_k127_8413628_0	926550.CLDAP_04590	2.653e-151	489.0	COG0014@1|root,COG0014@2|Bacteria,2G5TY@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_8413628_3	926550.CLDAP_34270	1.555e-11	66.0	COG1482@1|root,COG1482@2|Bacteria,2G6I2@200795|Chloroflexi	200795|Chloroflexi	G	PFAM mannose-6-phosphate isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
LZS2_k127_8426092_3	383372.Rcas_0210	3.016e-28	118.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_8426092_0	1128421.JAGA01000002_gene1016	4.446e-103	346.0	COG0123@1|root,COG0123@2|Bacteria,2NPB6@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS2_k127_8426092_1	211165.AJLN01000114_gene5953	5.377e-61	218.0	COG0500@1|root,COG2226@2|Bacteria,1G4JN@1117|Cyanobacteria,1JJFD@1189|Stigonemataceae	1117|Cyanobacteria	Q	AdoMet dependent proline di-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
LZS2_k127_8426092_2	1136417.AZWE01000029_gene215	8.211e-44	164.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4D93A@85008|Micromonosporales	201174|Actinobacteria	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_8428496_0	765420.OSCT_0642	5.837e-115	374.0	COG2197@1|root,COG2197@2|Bacteria,2G7U4@200795|Chloroflexi,376QK@32061|Chloroflexia	32061|Chloroflexia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_8428496_3	1719.CPTC_00838	7.663e-14	82.0	COG0671@1|root,COG0671@2|Bacteria,2IREX@201174|Actinobacteria,22PAG@1653|Corynebacteriaceae	201174|Actinobacteria	I	Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
LZS2_k127_8428496_1	1242864.D187_003500	6.701e-77	276.0	COG0642@1|root,COG2205@2|Bacteria	1242864.D187_003500|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8428496_2	469371.Tbis_2599	9.289e-45	164.0	COG1032@1|root,COG1032@2|Bacteria,2HW71@201174|Actinobacteria,4E7P4@85010|Pseudonocardiales	201174|Actinobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS2_k127_8435241_1	1392487.JIAD01000001_gene460	1.74e-20	93.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,25UVS@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
LZS2_k127_8435241_0	765420.OSCT_0452	1.347e-66	246.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3766E@32061|Chloroflexia	32061|Chloroflexia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
LZS2_k127_8437137_2	926550.CLDAP_32160	9.544e-152	491.0	COG1070@1|root,COG1070@2|Bacteria,2G7ND@200795|Chloroflexi	200795|Chloroflexi	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
LZS2_k127_8437137_3	1122915.AUGY01000017_gene2541	3.743e-145	466.0	COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,4HDRR@91061|Bacilli,2764R@186822|Paenibacillaceae	91061|Bacilli	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
LZS2_k127_8437137_4	324057.Pjdr2_5328	1.986e-130	423.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,26UGN@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
LZS2_k127_8437137_0	1122927.KB895412_gene1015	4.952e-222	698.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,26SVT@186822|Paenibacillaceae	91061|Bacilli	G	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
LZS2_k127_8437137_7	1122915.AUGY01000010_gene4620	2.454e-74	263.0	COG1609@1|root,COG1609@2|Bacteria,1TRZW@1239|Firmicutes,4HD7B@91061|Bacilli,274HM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03435	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
LZS2_k127_8437137_1	518766.Rmar_0086	2.804e-163	519.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1FJJ9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_8437137_8	754035.Mesau_02654	2.735e-31	144.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,43PM5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Hydrolase_4,Trans_reg_C
LZS2_k127_8437137_5	1121377.KB906402_gene3232	1.015e-117	423.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
LZS2_k127_8437137_6	1131269.AQVV01000024_gene2368	9.285e-85	319.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667	SBP_bac_5
LZS2_k127_843882_4	383372.Rcas_0962	6.282e-13	77.0	2DN0I@1|root,32UR2@2|Bacteria,2G8Y2@200795|Chloroflexi,375Q5@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
LZS2_k127_843882_2	765420.OSCT_0550	2.077e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,2GBT3@200795|Chloroflexi,376HQ@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_843882_0	357808.RoseRS_3736	2.547e-137	451.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,2GBIC@200795|Chloroflexi,3780I@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_843882_1	1232410.KI421421_gene3543	1.078e-129	419.0	COG2820@1|root,COG2820@2|Bacteria,1QVR4@1224|Proteobacteria,42N9X@68525|delta/epsilon subdivisions,2WJ8F@28221|Deltaproteobacteria,43S8P@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylase superfamily	-	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS2_k127_843882_3	561175.KB894094_gene1497	7.299e-53	202.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,4EFYJ@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
LZS2_k127_8443753_1	667632.KB890165_gene2368	2.844e-89	298.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2VJ3R@28216|Betaproteobacteria,1KGMG@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10553	ko02010,map02010	M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.7	-	-	BPD_transp_2
LZS2_k127_8443753_0	266117.Rxyl_3003	3.964e-108	361.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4CP7R@84995|Rubrobacteria	201174|Actinobacteria	P	PFAM ABC transporter related	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
LZS2_k127_8448041_3	391625.PPSIR1_13430	3.108e-52	190.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,42RKE@68525|delta/epsilon subdivisions,2WS0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
LZS2_k127_8448041_4	290315.Clim_1053	6.773e-50	184.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	chpE	-	-	ko:K06600,ko:K06895	-	-	-	-	ko00000,ko02000,ko02035	2.A.75.1,2.A.76	-	-	LysE
LZS2_k127_8448041_8	497964.CfE428DRAFT_3727	4.947e-21	100.0	2FH6M@1|root,34912@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
LZS2_k127_8448041_2	926569.ANT_11680	1.423e-91	324.0	COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal
LZS2_k127_8448041_6	118168.MC7420_4961	1.355e-37	160.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1H8X5@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_8448041_7	706587.Desti_1467	1.945e-36	142.0	COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,430JJ@68525|delta/epsilon subdivisions,2WVQQ@28221|Deltaproteobacteria,2MRZH@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
LZS2_k127_8448041_9	706587.Desti_1963	3.034e-10	68.0	2DPY2@1|root,333WA@2|Bacteria,1NDT4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AP2
LZS2_k127_8448041_0	1122931.AUAE01000031_gene2875	3.078e-278	876.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,22WAD@171551|Porphyromonadaceae	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
LZS2_k127_8448041_1	926569.ANT_18650	3.771e-96	324.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS2_k127_8448041_5	237368.SCABRO_02220	3.363e-41	160.0	COG1277@1|root,COG1277@2|Bacteria,2J0HW@203682|Planctomycetes	203682|Planctomycetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
LZS2_k127_8457477_0	439235.Dalk_1862	1.485e-149	491.0	COG1119@1|root,COG1119@2|Bacteria,1MVVM@1224|Proteobacteria,42RN3@68525|delta/epsilon subdivisions,2X6YZ@28221|Deltaproteobacteria,2MPYI@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.34	ko:K02013,ko:K05776	ko02010,map02010	M00189,M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
LZS2_k127_8457477_6	991905.SL003B_0888	6.925e-39	154.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2TU6M@28211|Alphaproteobacteria,4BQEX@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_8457477_1	72664.XP_006416624.1	3.696e-142	465.0	COG0191@1|root,COG2084@1|root,KOG0409@2759|Eukaryota,KOG4153@2759|Eukaryota,37I1B@33090|Viridiplantae,3GEGM@35493|Streptophyta,3HMDZ@3699|Brassicales	35493|Streptophyta	G	Ketose-bisphosphate aldolase class-II family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537,F_bP_aldolase,NAD_binding_11,NAD_binding_2
LZS2_k127_8457477_5	452637.Oter_1273	8.032e-84	285.0	COG1028@1|root,COG1028@2|Bacteria,46U4E@74201|Verrucomicrobia,3K8V0@414999|Opitutae	414999|Opitutae	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
LZS2_k127_8457477_3	335543.Sfum_0938	2.502e-97	323.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2MQFJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
LZS2_k127_8457477_7	867845.KI911784_gene3283	9.509e-30	126.0	COG0789@1|root,COG0789@2|Bacteria,2GBIN@200795|Chloroflexi,375XH@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
LZS2_k127_8457477_2	574087.Acear_0541	4.322e-102	347.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WBFD@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS2_k127_8457477_4	926550.CLDAP_19100	1.866e-88	302.0	COG0181@1|root,COG0181@2|Bacteria,2G6JU@200795|Chloroflexi	200795|Chloroflexi	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
LZS2_k127_8457477_8	1173025.GEI7407_0064	5.692e-27	119.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1G1Y4@1117|Cyanobacteria,1H8D0@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
LZS2_k127_8460184_3	292564.Cyagr_0641	2.535e-09	59.0	COG4031@1|root,COG4031@2|Bacteria,1G7XS@1117|Cyanobacteria,22TT8@167375|Cyanobium	1117|Cyanobacteria	S	Predicted metal-binding protein (DUF2103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2103
LZS2_k127_8460184_0	130081.XP_005707916.1	8.346e-132	426.0	COG0190@1|root,KOG0089@2759|Eukaryota	2759|Eukaryota	H	methenyltetrahydrofolate cyclohydrolase activity	-	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019219,GO:0019222,GO:0019238,GO:0019752,GO:0031323,GO:0034641,GO:0042558,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044030,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046653,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051186,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901360,GO:1901564	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288	ko00670,ko01100,map00670,map01100	M00141	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
LZS2_k127_8460184_2	1134912.AJTV01000021_gene3011	3.878e-17	88.0	COG0664@1|root,COG0664@2|Bacteria,1RII7@1224|Proteobacteria,2UA8E@28211|Alphaproteobacteria,37072@31993|Methylocystaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
LZS2_k127_8460184_1	1449126.JQKL01000002_gene1553	2.505e-28	120.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
LZS2_k127_8460184_4	1379698.RBG1_1C00001G0047	0.0003245	43.0	COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
LZS2_k127_8465163_6	1408422.JHYF01000009_gene1999	7.807e-28	118.0	COG3635@1|root,COG3635@2|Bacteria,1UIDA@1239|Firmicutes,25EIA@186801|Clostridia	186801|Clostridia	G	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
LZS2_k127_8465163_1	608506.COB47_0712	2.792e-171	547.0	COG3693@1|root,COG3693@2|Bacteria,1UZWX@1239|Firmicutes,24BPR@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
LZS2_k127_8465163_2	309801.trd_1352	1.49e-87	305.0	COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi,27YZX@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
LZS2_k127_8465163_0	926550.CLDAP_18560	1.457e-249	776.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS2_k127_8465163_5	926550.CLDAP_18620	5.627e-33	133.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
LZS2_k127_8465163_4	1128421.JAGA01000002_gene1268	9.164e-37	142.0	COG0316@1|root,COG0316@2|Bacteria,2NPZK@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the HesB IscA family	erpA	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016020,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:0071944,GO:1901564	-	ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
LZS2_k127_8465163_7	926550.CLDAP_35190	4.146e-24	106.0	2FKJC@1|root,34C6D@2|Bacteria,2G9T3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8465163_3	926550.CLDAP_09490	1.102e-39	151.0	COG2313@1|root,COG2313@2|Bacteria,2G5KC@200795|Chloroflexi	200795|Chloroflexi	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
LZS2_k127_8470327_9	357808.RoseRS_2884	7.745e-32	126.0	COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi,376KP@32061|Chloroflexia	32061|Chloroflexia	G	PFAM Xylose isomerase domain protein TIM barrel	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
LZS2_k127_8470327_2	886293.Sinac_1525	3.694e-137	444.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
LZS2_k127_8470327_0	926569.ANT_24910	4.864e-253	788.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
LZS2_k127_8470327_1	1173022.Cri9333_0749	5.276e-158	503.0	COG0667@1|root,COG0667@2|Bacteria,1G3WV@1117|Cyanobacteria,1HH84@1150|Oscillatoriales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
LZS2_k127_8470327_10	1408254.T458_19885	2.114e-30	134.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,4HK2P@91061|Bacilli,276QJ@186822|Paenibacillaceae	91061|Bacilli	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS2_k127_8470327_5	1382306.JNIM01000001_gene3678	1.02e-106	359.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
LZS2_k127_8470327_13	980584.AFPB01000174_gene1559	1.902e-05	57.0	COG1652@1|root,COG1652@2|Bacteria,4NMED@976|Bacteroidetes,1I1AU@117743|Flavobacteriia	976|Bacteroidetes	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
LZS2_k127_8470327_11	292459.STH620	1.011e-08	68.0	COG3255@1|root,COG3255@2|Bacteria,1VFEY@1239|Firmicutes,24QXQ@186801|Clostridia	186801|Clostridia	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
LZS2_k127_8470327_6	1123250.KB908387_gene557	2.245e-101	335.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4H223@909932|Negativicutes	909932|Negativicutes	E	ABC transporter, ATP-binding protein	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
LZS2_k127_8470327_4	926550.CLDAP_29810	7.351e-107	354.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
LZS2_k127_8470327_3	1128421.JAGA01000002_gene1296	4.01e-123	414.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS2_k127_8470327_7	926550.CLDAP_29790	3.036e-101	342.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS2_k127_8470327_8	1128421.JAGA01000002_gene1294	1.057e-82	293.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS2_k127_8477529_0	1250006.JHZZ01000001_gene238	3.703e-83	304.0	COG2133@1|root,COG3568@1|root,COG5492@1|root,COG2133@2|Bacteria,COG3568@2|Bacteria,COG5492@2|Bacteria,4NPDY@976|Bacteroidetes,1I1DH@117743|Flavobacteriia,3VXGV@52959|Polaribacter	976|Bacteroidetes	GN	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8477529_1	1123261.AXDW01000009_gene4	1.005e-07	55.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1X3CZ@135614|Xanthomonadales	135614|Xanthomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS2_k127_8497970_1	526227.Mesil_3179	2.171e-89	306.0	COG1609@1|root,COG1609@2|Bacteria,1WMBZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
LZS2_k127_8497970_0	42256.RradSPS_0358	5.838e-209	681.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
LZS2_k127_8554781_4	935848.JAEN01000005_gene3677	4.646e-09	61.0	COG0561@1|root,COG0561@2|Bacteria,1PD4E@1224|Proteobacteria,2UH8B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sucrose-6F-phosphate phosphohydrolase	-	-	3.1.3.24	ko:K07024	ko00500,map00500	-	R00805,R06211	RC00017	ko00000,ko00001,ko01000	-	-	-	S6PP
LZS2_k127_8554781_1	1250006.JHZZ01000001_gene2154	3.716e-163	537.0	COG0561@1|root,COG3408@1|root,COG0561@2|Bacteria,COG3408@2|Bacteria,4NGZM@976|Bacteroidetes,1I02Y@117743|Flavobacteriia	976|Bacteroidetes	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100,S6PP
LZS2_k127_8554781_0	1128421.JAGA01000004_gene2674	4.94e-232	738.0	COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria	2|Bacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
LZS2_k127_8554781_3	56110.Oscil6304_1118	3.513e-17	88.0	COG3224@1|root,COG3224@2|Bacteria,1G83R@1117|Cyanobacteria,1HC4F@1150|Oscillatoriales	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8554781_2	1480694.DC28_12355	1.459e-97	323.0	COG0395@1|root,COG0395@2|Bacteria,2J5Z6@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119,ko:K10234	ko02010,map02010	M00196,M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28,3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
LZS2_k127_8557592_0	926550.CLDAP_18940	5.495e-72	253.0	COG0472@1|root,COG0472@2|Bacteria,2G6H5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
LZS2_k127_8557592_1	1121104.AQXH01000001_gene1975	3.757e-38	149.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes	976|Bacteroidetes	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS2_k127_8570311_1	926550.CLDAP_07170	3.912e-75	263.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
LZS2_k127_8570311_0	926550.CLDAP_07180	2.892e-85	292.0	COG1131@1|root,COG1131@2|Bacteria,2G7PN@200795|Chloroflexi	200795|Chloroflexi	PV	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K07218	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,NosD
LZS2_k127_8570311_2	926550.CLDAP_07190	2.541e-64	225.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
LZS2_k127_8589208_5	926569.ANT_16920	5.303e-37	142.0	COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	-	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
LZS2_k127_8589208_3	926569.ANT_16940	4.955e-60	224.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_8589208_0	926569.ANT_16950	8.164e-120	396.0	COG0436@1|root,COG0436@2|Bacteria,2G60K@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_8589208_4	1449126.JQKL01000021_gene91	4.182e-42	165.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,268GU@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
LZS2_k127_8589208_1	383372.Rcas_1626	1.234e-106	360.0	COG0438@1|root,COG0438@2|Bacteria,2G60E@200795|Chloroflexi,376AW@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
LZS2_k127_8589208_2	383372.Rcas_2975	2.028e-72	268.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,2G9NN@200795|Chloroflexi	200795|Chloroflexi	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS2_k127_8589208_6	378806.STAUR_2341	8.264e-05	50.0	COG2885@1|root,COG2931@1|root,COG2885@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42T9J@68525|delta/epsilon subdivisions,2WU7T@28221|Deltaproteobacteria,2YWI9@29|Myxococcales	28221|Deltaproteobacteria	MQ	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2
LZS2_k127_8610967_0	502025.Hoch_6213	5.378e-90	320.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_8635995_0	1120950.KB892708_gene4260	4.779e-157	501.0	COG3458@1|root,COG3458@2|Bacteria,2GNHH@201174|Actinobacteria,4DRMF@85009|Propionibacteriales	201174|Actinobacteria	Q	Acetyl xylan esterase (AXE1)	axe1	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
LZS2_k127_8635995_1	1117379.BABA_22543	4.632e-32	145.0	COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,4HBE4@91061|Bacilli,1ZD5Z@1386|Bacillus	91061|Bacilli	M	Spore Coat	cotH	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
LZS2_k127_8635995_2	326427.Cagg_2774	5.03e-11	70.0	COG2331@1|root,COG2331@2|Bacteria,2G9QZ@200795|Chloroflexi,377TZ@32061|Chloroflexia	32061|Chloroflexia	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
LZS2_k127_8643011_1	370438.PTH_1313	1.42e-44	171.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,2629V@186807|Peptococcaceae	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
LZS2_k127_8643011_0	1521187.JPIM01000001_gene843	2.381e-52	198.0	COG0300@1|root,COG0300@2|Bacteria,2G8KG@200795|Chloroflexi,376QV@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_8643011_2	158190.SpiGrapes_1178	5.253e-41	162.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	ilvE	GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394	Aminotran_4
LZS2_k127_8643011_4	1227495.C487_17965	2.054e-11	70.0	arCOG03392@1|root,arCOG03392@2157|Archaea,2XYTK@28890|Euryarchaeota,23WQS@183963|Halobacteria	183963|Halobacteria	S	Membrane-bound metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
LZS2_k127_8643011_5	1128421.JAGA01000002_gene1331	2.621e-11	68.0	2ED7R@1|root,3374C@2|Bacteria,2NS2D@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8643011_3	552811.Dehly_1387	2.516e-38	151.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi,34CVT@301297|Dehalococcoidia	301297|Dehalococcoidia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
LZS2_k127_8643267_0	350054.Mflv_4294	1.596e-164	527.0	COG3621@1|root,COG3621@2|Bacteria,2I97F@201174|Actinobacteria,23F3R@1762|Mycobacteriaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
LZS2_k127_8643267_2	269797.Mbar_A1908	2.42e-26	121.0	arCOG03980@1|root,arCOG03980@2157|Archaea	2157|Archaea	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_8643267_1	383372.Rcas_2506	7.091e-37	147.0	COG1287@1|root,COG1287@2|Bacteria,2GAA0@200795|Chloroflexi,376PD@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8643267_3	1128421.JAGA01000002_gene1597	3.635e-10	70.0	2DWJH@1|root,340NM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8656312_8	316274.Haur_0218	2.164e-23	100.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
LZS2_k127_8656312_10	1044.EH31_05020	1.082e-08	68.0	COG2208@1|root,COG4252@1|root,COG2208@2|Bacteria,COG4252@2|Bacteria,1QUNZ@1224|Proteobacteria,2TW2I@28211|Alphaproteobacteria,2K2IY@204457|Sphingomonadales	204457|Sphingomonadales	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,SpoIIE
LZS2_k127_8656312_5	383372.Rcas_2639	1.983e-76	278.0	COG0642@1|root,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS_4
LZS2_k127_8656312_7	926550.CLDAP_16840	1.24e-55	216.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
LZS2_k127_8656312_11	1028801.RG1141_CH13090	3.407e-07	57.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,2UC5S@28211|Alphaproteobacteria,4BFIU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
LZS2_k127_8656312_9	926550.CLDAP_16820	9.504e-20	100.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	3.1.21.3,5.4.99.60,5.4.99.61	ko:K01153,ko:K06042,ko:K22491	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000,ko02048,ko03000	-	-	-	B12-binding,B12-binding_2,EcoEI_R_C,HTH_17,Helicase_C,MerR_1,ResIII
LZS2_k127_8656312_3	926550.CLDAP_09860	7.414e-94	317.0	COG2035@1|root,COG2035@2|Bacteria,2G6J1@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
LZS2_k127_8656312_0	926550.CLDAP_02810	3.8e-247	775.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_8656312_4	926569.ANT_03770	4.96e-79	269.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
LZS2_k127_8656312_6	926569.ANT_06590	1.361e-70	248.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS2_k127_8656312_2	525904.Tter_0255	1.761e-106	358.0	COG0624@1|root,COG0624@2|Bacteria,2NNX2@2323|unclassified Bacteria	2|Bacteria	E	Peptidase dimerisation domain	ygeY	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_8656312_1	1121930.AQXG01000001_gene1284	1.146e-167	539.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,1IPB3@117747|Sphingobacteriia	976|Bacteroidetes	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
LZS2_k127_8666890_1	555079.Toce_0385	1.947e-49	186.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia,42G3H@68295|Thermoanaerobacterales	186801|Clostridia	K	Transcriptional regulator IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
LZS2_k127_8666890_2	196162.Noca_2229	1.864e-05	57.0	COG1652@1|root,COG3170@1|root,COG1652@2|Bacteria,COG3170@2|Bacteria,2I8YV@201174|Actinobacteria,4DRF1@85009|Propionibacteriales	201174|Actinobacteria	NU	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_8666890_0	391613.RTM1035_07008	1.602e-114	385.0	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,2TSZ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS2_k127_8668926_8	926569.ANT_06790	3.622e-66	235.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
LZS2_k127_8668926_4	926569.ANT_06780	2.031e-86	289.0	COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
LZS2_k127_8668926_5	926569.ANT_06770	1.065e-82	282.0	COG2267@1|root,COG2267@2|Bacteria,2G761@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_8668926_1	316274.Haur_4116	4.886e-144	469.0	COG1207@1|root,COG1207@2|Bacteria,2G7KV@200795|Chloroflexi,374WC@32061|Chloroflexia	32061|Chloroflexia	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
LZS2_k127_8668926_2	555079.Toce_2079	1.038e-119	395.0	COG5322@1|root,COG5322@2|Bacteria,1TSXZ@1239|Firmicutes,24992@186801|Clostridia,42EPQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
LZS2_k127_8668926_3	926569.ANT_06590	1.382e-96	324.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS2_k127_8668926_0	926569.ANT_06600	4.571e-165	585.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS2_k127_8668926_10	926569.ANT_06610	4.264e-39	149.0	COG0745@1|root,COG0745@2|Bacteria,2G986@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_8668926_9	357808.RoseRS_4453	1.097e-53	199.0	COG2267@1|root,COG2267@2|Bacteria,2GA7T@200795|Chloroflexi,3780R@32061|Chloroflexia	32061|Chloroflexia	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_8668926_11	357808.RoseRS_4449	8.235e-38	150.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi,375HS@32061|Chloroflexia	32061|Chloroflexia	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
LZS2_k127_8668926_7	926550.CLDAP_35360	7.048e-76	271.0	COG1994@1|root,COG1994@2|Bacteria,2G8E2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
LZS2_k127_8668926_12	439235.Dalk_2422	4.551e-27	127.0	COG1309@1|root,COG1309@2|Bacteria,1Q1V7@1224|Proteobacteria,431BH@68525|delta/epsilon subdivisions,2WWAK@28221|Deltaproteobacteria,2MNTV@213118|Desulfobacterales	28221|Deltaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8668926_6	1499967.BAYZ01000154_gene1474	1.328e-82	294.0	2E7SP@1|root,3327V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8676651_0	1157490.EL26_22080	4.574e-234	740.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,2790Z@186823|Alicyclobacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
LZS2_k127_8676651_1	1238182.C882_2436	8.311e-68	236.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,2JRV6@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_8694495_0	926550.CLDAP_03240	8.46e-48	197.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	-
LZS2_k127_8694495_2	926550.CLDAP_17520	2.392e-18	101.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_8694495_1	1499967.BAYZ01000009_gene5328	6.217e-42	168.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
LZS2_k127_8703432_2	1265505.ATUG01000001_gene3978	2.271e-16	83.0	COG2203@1|root,COG2203@2|Bacteria,1NT6X@1224|Proteobacteria,42XRB@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
LZS2_k127_8703432_1	1499967.BAYZ01000044_gene3007	9.25e-69	249.0	COG0687@1|root,COG0687@2|Bacteria	2|Bacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8,TAT_signal
LZS2_k127_8703432_0	1242864.D187_009246	1.329e-174	580.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X83K@28221|Deltaproteobacteria,2YUDP@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
LZS2_k127_8719968_7	926550.CLDAP_25550	8.133e-54	214.0	COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,2G8PE@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
LZS2_k127_8719968_4	865861.AZSU01000001_gene221	3.156e-103	346.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia,36DEF@31979|Clostridiaceae	186801|Clostridia	G	PFAM peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
LZS2_k127_8719968_2	1128421.JAGA01000002_gene731	8.676e-175	557.0	COG2195@1|root,COG2195@2|Bacteria,2NPYT@2323|unclassified Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
LZS2_k127_8719968_1	292459.STH1987	1.132e-187	603.0	COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,25CE1@186801|Clostridia	186801|Clostridia	E	Oligoendopeptidase, pepF M3 family	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
LZS2_k127_8719968_3	649638.Trad_0272	1.085e-145	473.0	COG2309@1|root,COG2309@2|Bacteria,1WI5P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
LZS2_k127_8719968_9	1469557.JSWF01000030_gene3464	4.522e-34	135.0	2C1YK@1|root,32X9M@2|Bacteria	2|Bacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
LZS2_k127_8719968_0	926550.CLDAP_38260	3.417e-238	757.0	COG0507@1|root,COG0632@1|root,COG0507@2|Bacteria,COG0632@2|Bacteria,2G626@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
LZS2_k127_8719968_11	926550.CLDAP_19750	8.457e-12	69.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
LZS2_k127_8719968_5	926569.ANT_11320	1.533e-83	289.0	COG0613@1|root,COG0613@2|Bacteria,2G9BU@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8719968_12	1229172.JQFA01000005_gene239	5.331e-06	59.0	COG3381@1|root,COG3381@2|Bacteria,1G1F7@1117|Cyanobacteria,1H8IH@1150|Oscillatoriales	1117|Cyanobacteria	S	protein complex oligomerization	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8719968_6	56110.Oscil6304_4971	1.73e-63	241.0	COG0457@1|root,COG0457@2|Bacteria	56110.Oscil6304_4971|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8719968_8	479434.Sthe_0323	2.591e-40	169.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_8747377_1	1379698.RBG1_1C00001G1071	4.396e-60	214.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS2_k127_8747377_2	326427.Cagg_0145	4.391e-59	215.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2G5VK@200795|Chloroflexi,37589@32061|Chloroflexia	32061|Chloroflexia	E	glutamate synthase, alpha subunit domain protein	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
LZS2_k127_8747377_0	398767.Glov_2618	8.751e-155	501.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43T9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
LZS2_k127_880643_0	29306.JOBE01000021_gene415	6.401e-109	356.0	COG3497@1|root,COG3497@2|Bacteria,2GMJA@201174|Actinobacteria	201174|Actinobacteria	S	tail sheath protein	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	Phage_sheath_1,Phage_sheath_1C
LZS2_k127_880643_1	1382306.JNIM01000001_gene3330	4.697e-46	170.0	2ACY3@1|root,312JQ@2|Bacteria,2G8H3@200795|Chloroflexi	200795|Chloroflexi	S	T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
LZS2_k127_880643_2	1173028.ANKO01000114_gene6168	3.107e-45	166.0	arCOG11412@1|root,31S84@2|Bacteria,1G5ZP@1117|Cyanobacteria,1HBJ9@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_880643_4	298654.FraEuI1c_7049	1.956e-15	77.0	2BDQX@1|root,327EJ@2|Bacteria,2HU32@201174|Actinobacteria,4EWQU@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_880643_3	118161.KB235920_gene5975	2.806e-29	121.0	2DMQT@1|root,32T2H@2|Bacteria,1G73M@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM T4-like virus tail tube protein gp19	-	-	-	-	-	-	-	-	-	-	-	-	Phage_T4_gp19
LZS2_k127_8834554_0	383372.Rcas_3549	4e-70	246.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi,3758C@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_8834554_2	383372.Rcas_2221	3.789e-29	126.0	28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi,375P3@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8834554_1	247490.KSU1_B0649	5.449e-31	132.0	29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8839341_7	926550.CLDAP_39450	2.093e-12	68.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
LZS2_k127_8839341_0	926569.ANT_10860	0.0	1675.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
LZS2_k127_8839341_6	1430331.EP10_08275	7.177e-20	100.0	COG4974@1|root,COG4974@2|Bacteria,1V2D0@1239|Firmicutes,4IQMK@91061|Bacilli	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS2_k127_8839341_2	926550.CLDAP_34520	1.407e-122	402.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS2_k127_8839341_5	926550.CLDAP_18780	8.521e-77	263.0	COG1648@1|root,COG1648@2|Bacteria,2G753@200795|Chloroflexi	200795|Chloroflexi	H	Sirohaem biosynthesis protein central	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
LZS2_k127_8839341_3	765420.OSCT_2402	3.333e-87	296.0	COG0007@1|root,COG0007@2|Bacteria,2G7RZ@200795|Chloroflexi,3772A@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
LZS2_k127_8839341_4	926550.CLDAP_18790	1.459e-80	277.0	COG0175@1|root,COG0175@2|Bacteria,2G8H1@200795|Chloroflexi	200795|Chloroflexi	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
LZS2_k127_8839341_1	1128427.KB904821_gene3906	6.934e-294	909.0	COG0155@1|root,COG0155@2|Bacteria,1G0Z6@1117|Cyanobacteria,1H7MU@1150|Oscillatoriales	1117|Cyanobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
LZS2_k127_8863518_0	926550.CLDAP_15350	1.912e-239	762.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
LZS2_k127_8863518_12	1307761.L21SP2_0913	1.28e-21	100.0	COG0745@1|root,COG0745@2|Bacteria,2J7CK@203691|Spirochaetes	203691|Spirochaetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07657,ko:K18941	ko02020,map02020	M00434,M00716,M00717	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_8863518_6	926569.ANT_00470	2.349e-88	298.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_8863518_9	926569.ANT_24730	2.381e-63	225.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi	200795|Chloroflexi	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
LZS2_k127_8863518_13	1123499.KB908018_gene2013	2.399e-11	69.0	COG2018@1|root,COG2018@2|Bacteria,1RIQC@1224|Proteobacteria,2VTV9@28216|Betaproteobacteria,2KREG@206351|Neisseriales	206351|Neisseriales	S	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
LZS2_k127_8863518_14	1173264.KI913949_gene2316	2.899e-07	57.0	COG2018@1|root,COG2018@2|Bacteria,1G7A5@1117|Cyanobacteria,1HBQ8@1150|Oscillatoriales	1117|Cyanobacteria	S	Roadblock LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
LZS2_k127_8863518_7	765420.OSCT_3196	9.364e-83	304.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_8863518_11	1047013.AQSP01000131_gene1797	3.208e-25	124.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_8863518_15	1128421.JAGA01000003_gene3252	1.712e-05	59.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_circ_N,DUF928,LysM
LZS2_k127_8863518_2	314345.SPV1_05864	2.326e-149	480.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria	1224|Proteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metAS	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_4539,iSBO_1134.SBO_4033,iSbBS512_1146.SbBS512_E4507	HTS
LZS2_k127_8863518_1	2340.JV46_24900	1.022e-221	692.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,1T1GA@1236|Gammaproteobacteria,1J5D4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	O-acetylhomoserine sulfhydrylase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	iJN746.PP_2528	Cys_Met_Meta_PP
LZS2_k127_8863518_5	926550.CLDAP_23060	6.373e-108	359.0	COG0524@1|root,COG0524@2|Bacteria,2G6W1@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS2_k127_8863518_10	311424.DhcVS_1127	1.718e-54	203.0	COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi,34CKX@301297|Dehalococcoidia	301297|Dehalococcoidia	G	DeoC/LacD family aldolase	-	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
LZS2_k127_8863518_8	649638.Trad_0655	1.419e-66	241.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1
LZS2_k127_8863518_4	521045.Kole_0686	5.374e-136	445.0	COG4573@1|root,COG4573@2|Bacteria	2|Bacteria	G	galactitol metabolic process	kbaZ	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	5.1.3.40	ko:K02775,ko:K16371,ko:K21622	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R01069,R05570,R11623	RC00017,RC00438,RC00439,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	iE2348C_1286.E2348C_2240,iECIAI1_1343.ECIAI1_3280,iECO111_1330.ECO111_2811,iECO26_1355.ECO26_3004,iYL1228.KPN_03547	Tagatose_6_P_K
LZS2_k127_8863518_3	1267533.KB906737_gene1499	1.472e-138	448.0	COG3345@1|root,COG3345@2|Bacteria,3Y6JU@57723|Acidobacteria,2JKCG@204432|Acidobacteriia	204432|Acidobacteriia	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
LZS2_k127_88694_4	688269.Theth_1031	1.136e-74	253.0	COG2403@1|root,COG2403@2|Bacteria,2GCJ5@200918|Thermotogae	200918|Thermotogae	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_88694_6	926550.CLDAP_15680	2.715e-52	193.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
LZS2_k127_88694_12	1410612.JNKO01000006_gene1201	1.929e-06	59.0	COG1826@1|root,COG1826@2|Bacteria,1VHQF@1239|Firmicutes,24QW5@186801|Clostridia,2PSIY@265975|Oribacterium	186801|Clostridia	U	mttA/Hcf106 family	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
LZS2_k127_88694_9	926569.ANT_14610	2.451e-29	123.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
LZS2_k127_88694_3	272558.10175111	1.739e-83	284.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1ZCDY@1386|Bacillus	91061|Bacilli	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
LZS2_k127_88694_2	357808.RoseRS_3469	1.336e-90	307.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,375EH@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
LZS2_k127_88694_11	220668.lp_1535a	2.905e-15	77.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,4HNIZ@91061|Bacilli,3FCDY@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
LZS2_k127_88694_8	485913.Krac_8242	5.129e-32	132.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
LZS2_k127_88694_10	926569.ANT_15290	1.808e-26	115.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_88694_7	158822.LH89_11460	9.475e-48	176.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0053,iSDY_1059.SDY_4064	CTP_transf_like
LZS2_k127_88694_0	635013.TherJR_2099	2.916e-192	632.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
LZS2_k127_88694_5	316274.Haur_0364	4.758e-62	223.0	COG1307@1|root,COG1307@2|Bacteria,2G6P2@200795|Chloroflexi,374VJ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
LZS2_k127_88694_1	316274.Haur_0365	8.29e-93	317.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi,376UA@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
LZS2_k127_8874115_5	545695.TREAZ_1079	4.869e-08	64.0	COG0699@1|root,COG0699@2|Bacteria	2|Bacteria	T	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
LZS2_k127_8874115_4	706587.Desti_1672	2.389e-43	162.0	COG0432@1|root,COG0432@2|Bacteria,1N5SN@1224|Proteobacteria,42SJC@68525|delta/epsilon subdivisions,2WP9F@28221|Deltaproteobacteria,2MRXI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS2_k127_8874115_0	926569.ANT_24980	1.349e-245	784.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi	200795|Chloroflexi	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
LZS2_k127_8874115_1	926550.CLDAP_01050	1.729e-137	445.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
LZS2_k127_8874115_3	1268072.PSAB_03025	5.681e-77	261.0	COG0778@1|root,COG0778@2|Bacteria,1V4ZI@1239|Firmicutes	1239|Firmicutes	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS2_k127_8874115_2	42256.RradSPS_0358	3.797e-111	374.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
LZS2_k127_8886713_0	1499967.BAYZ01000050_gene2809	5.589e-165	525.0	COG1085@1|root,COG1085@2|Bacteria,2NQA3@2323|unclassified Bacteria	2|Bacteria	H	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECUMN_1333.ECUMN_0842,iYL1228.KPN_00772	GalP_UDP_tr_C,GalP_UDP_transf
LZS2_k127_8886713_2	926569.ANT_11190	9.547e-100	327.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
LZS2_k127_8886713_1	867845.KI911784_gene620	5.357e-104	351.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi,3757S@32061|Chloroflexia	32061|Chloroflexia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
LZS2_k127_8886713_5	1385935.N836_29710	4.137e-51	186.0	COG0454@1|root,COG0456@2|Bacteria,1G646@1117|Cyanobacteria,1HC70@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS2_k127_8886713_9	1047013.AQSP01000084_gene766	1.65e-08	59.0	COG0500@1|root,COG2226@2|Bacteria,2NQ3S@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.103,2.1.1.163,2.1.1.201	ko:K03183,ko:K05929	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00116,M00117	R02037,R04990,R04993,R06859,R06868,R06869,R08774,R09736	RC00003,RC00060,RC00181,RC00496,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
LZS2_k127_8886713_7	1303518.CCALI_01792	2.341e-26	118.0	arCOG09854@1|root,3325R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8886713_3	1341151.ASZU01000004_gene99	1.663e-87	296.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,27BNR@186824|Thermoactinomycetaceae	91061|Bacilli	J	tRNA (Guanine-1)-methyltransferase	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
LZS2_k127_8886713_6	479434.Sthe_0471	4.636e-39	149.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi,27YD2@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
LZS2_k127_8886713_4	1382306.JNIM01000001_gene3760	2.01e-61	218.0	COG0164@1|root,COG0164@2|Bacteria,2G6KR@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS2_k127_8886713_8	1185653.A1A1_14894	4.773e-15	83.0	COG0454@1|root,COG0456@2|Bacteria,1V7Q4@1239|Firmicutes,4HHHA@91061|Bacilli,26FFW@186818|Planococcaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS2_k127_890885_5	1382306.JNIM01000001_gene3883	4.008e-51	185.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi	200795|Chloroflexi	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
LZS2_k127_890885_8	1122609.AUGT01000026_gene64	0.0004248	49.0	COG3832@1|root,COG3832@2|Bacteria,2IDAT@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Polyketide_cyc2
LZS2_k127_890885_4	765420.OSCT_1148	4.261e-61	222.0	COG1105@1|root,COG1105@2|Bacteria,2G7B1@200795|Chloroflexi,3778X@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS2_k127_890885_2	926569.ANT_03800	9.295e-79	273.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
LZS2_k127_890885_1	926550.CLDAP_30410	2.828e-93	326.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,2G8CU@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
LZS2_k127_890885_3	1337936.IJ00_09315	3.736e-61	221.0	COG0546@1|root,COG0546@2|Bacteria,1G6T7@1117|Cyanobacteria	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_890885_7	1168059.KB899087_gene1061	1.041e-05	48.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS2_k127_890885_0	311424.DhcVS_979	3.119e-217	699.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UvrD/REP helicase N-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS2_k127_890885_6	1444309.JAQG01000099_gene4994	1.808e-10	66.0	COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,4HD89@91061|Bacilli,26VQB@186822|Paenibacillaceae	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
LZS2_k127_8919739_8	530564.Psta_4419	1.587e-19	97.0	COG4485@1|root,COG4485@2|Bacteria,2IZ5C@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_8919739_7	767817.Desgi_3262	1.528e-23	107.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,262DS@186807|Peptococcaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
LZS2_k127_8919739_3	326427.Cagg_2289	7.198e-92	312.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,3758V@32061|Chloroflexia	32061|Chloroflexia	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS2_k127_8919739_4	383372.Rcas_3593	5.809e-70	247.0	COG0863@1|root,COG0863@2|Bacteria,2GA9S@200795|Chloroflexi,374ZY@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
LZS2_k127_8919739_1	1170562.Cal6303_5468	1.215e-134	456.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG2905@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2905@2|Bacteria,1G09B@1117|Cyanobacteria,1HKCU@1161|Nostocales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_8919739_2	489825.LYNGBM3L_22900	3.051e-108	362.0	COG0642@1|root,COG2205@2|Bacteria,1G0YJ@1117|Cyanobacteria,1H7ER@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_8919739_6	926569.ANT_19360	1.147e-26	113.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_19360|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8919739_0	926569.ANT_09210	4.147e-201	649.0	COG0745@1|root,COG2114@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,dCache_1,dCache_3
LZS2_k127_8919739_5	999411.HMPREF1092_02916	6.203e-45	185.0	COG1361@1|root,COG1361@2|Bacteria,1UQ5B@1239|Firmicutes,24AUI@186801|Clostridia,36DY0@31979|Clostridiaceae	186801|Clostridia	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3794,SdrD_B
LZS2_k127_8919944_4	160799.PBOR_00990	4.312e-21	93.0	COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,4HDPM@91061|Bacilli,26RJB@186822|Paenibacillaceae	91061|Bacilli	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
LZS2_k127_8919944_0	314230.DSM3645_06249	7.075e-76	258.0	COG4430@1|root,COG4430@2|Bacteria,2J0DY@203682|Planctomycetes	203682|Planctomycetes	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
LZS2_k127_8919944_1	1267535.KB906767_gene648	2.854e-42	158.0	COG3795@1|root,COG3795@2|Bacteria,3Y8FZ@57723|Acidobacteria,2JNHB@204432|Acidobacteriia	204432|Acidobacteriia	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
LZS2_k127_8919944_3	43989.cce_4998	7.447e-30	123.0	COG4113@1|root,COG4113@2|Bacteria,1G7F7@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS2_k127_8919944_2	479434.Sthe_2726	1.554e-37	143.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia	189775|Thermomicrobia	O	Magnesium chelatase, subunit ChlI	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
LZS2_k127_8924120_0	671143.DAMO_0980	1.02e-50	184.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS2_k127_8924120_2	383372.Rcas_2772	3.168e-19	92.0	COG4244@1|root,COG4244@2|Bacteria,2G9QE@200795|Chloroflexi,3762C@32061|Chloroflexia	32061|Chloroflexia	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
LZS2_k127_8924120_1	309801.trd_0547	5.452e-50	183.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,27Y88@189775|Thermomicrobia	189775|Thermomicrobia	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
LZS2_k127_8924120_3	1173028.ANKO01000064_gene3113	1.102e-05	52.0	COG1413@1|root,COG1413@2|Bacteria,1G233@1117|Cyanobacteria,1H7RE@1150|Oscillatoriales	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,NB-ARC,Peptidase_C14,Trypsin_2
LZS2_k127_8934820_2	1385935.N836_24615	2.577e-12	81.0	COG4447@1|root,COG4447@2|Bacteria,1G2KP@1117|Cyanobacteria,1H6WW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
LZS2_k127_8934820_1	926569.ANT_30120	9.821e-35	149.0	COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS2_k127_8934820_0	383372.Rcas_4129	6.232e-48	179.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS2_k127_8938423_2	221288.JH992901_gene4436	6.809e-54	218.0	COG0683@1|root,COG1672@1|root,COG0683@2|Bacteria,COG1672@2|Bacteria,1G4E9@1117|Cyanobacteria	1117|Cyanobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	AAA_16,Peripla_BP_6,TPR_16
LZS2_k127_8938423_0	1120950.KB892745_gene2911	2.073e-82	287.0	COG0673@1|root,COG0673@2|Bacteria,2GN2Z@201174|Actinobacteria,4DPNI@85009|Propionibacteriales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	rifL	-	-	ko:K16015	ko01051,ko01130,map01051,map01130	-	R06594	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_8938423_4	1148.1653503	2.482e-16	89.0	COG2214@1|root,COG2214@2|Bacteria,1GABC@1117|Cyanobacteria	1117|Cyanobacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8938423_3	383372.Rcas_2392	9.222e-47	182.0	COG0631@1|root,COG0631@2|Bacteria,2G8I1@200795|Chloroflexi,375BS@32061|Chloroflexia	32061|Chloroflexia	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS2_k127_8938423_1	1122169.AREN01000010_gene2585	1.549e-57	209.0	COG1183@1|root,COG1183@2|Bacteria,1NGCJ@1224|Proteobacteria,1S88D@1236|Gammaproteobacteria,1JDWD@118969|Legionellales	118969|Legionellales	I	Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP	lidK	GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS2_k127_8938423_5	1087481.AGFX01000009_gene4848	7.628e-06	50.0	2B0GJ@1|root,31SU3@2|Bacteria,1TRKY@1239|Firmicutes,4HEZQ@91061|Bacilli,26QBY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_910193_2	321327.CYA_1808	5.166e-25	108.0	COG4031@1|root,COG4031@2|Bacteria,1G7XS@1117|Cyanobacteria,1H110@1129|Synechococcus	1117|Cyanobacteria	S	Predicted metal-binding protein (DUF2103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2103
LZS2_k127_910193_0	316274.Haur_4664	2.969e-92	318.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_910193_1	316274.Haur_4663	9.016e-78	266.0	COG0745@1|root,COG0745@2|Bacteria,2GAPE@200795|Chloroflexi,375I7@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_925475_8	243090.RB9128	9.189e-16	80.0	29CWT@1|root,2ZZUX@2|Bacteria	2|Bacteria	S	UPF0314 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2585
LZS2_k127_925475_1	43989.cce_1638	6.861e-109	360.0	COG0667@1|root,COG0667@2|Bacteria,1G6W7@1117|Cyanobacteria,3KKQM@43988|Cyanothece	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_925475_9	1410617.JHXH01000005_gene1090	1.706e-12	79.0	2DHAX@1|root,32U8Z@2|Bacteria,1VV1S@1239|Firmicutes,250GD@186801|Clostridia,3WM8Y@541000|Ruminococcaceae	186801|Clostridia	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
LZS2_k127_925475_7	1196028.ALEF01000018_gene2407	3.532e-17	91.0	COG1234@1|root,COG1234@2|Bacteria,1V1TF@1239|Firmicutes,4HFNV@91061|Bacilli,4C4JS@84406|Virgibacillus	91061|Bacilli	S	Beta-lactamase superfamily domain	yhfI	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
LZS2_k127_925475_3	926550.CLDAP_39240	5.755e-84	292.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
LZS2_k127_925475_2	926569.ANT_12110	1.326e-103	357.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	2.7.7.6	ko:K03046,ko:K03641,ko:K08642	ko00230,ko00240,ko01100,ko02024,ko03020,map00230,map00240,map01100,map02024,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03021,ko03400	2.C.1.2	-	-	Glyco_hydro_18,LysM,OapA,PD40,Peptidase_M23
LZS2_k127_925475_4	479434.Sthe_3085	3.427e-68	241.0	COG0725@1|root,COG0725@2|Bacteria,2G6J6@200795|Chloroflexi,27Y90@189775|Thermomicrobia	189775|Thermomicrobia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
LZS2_k127_925475_5	351160.RCIX1623	4.682e-68	241.0	COG0555@1|root,arCOG00164@2157|Archaea,2XVJ4@28890|Euryarchaeota,2N9S1@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM binding-protein-dependent transport systems inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
LZS2_k127_925475_0	933262.AXAM01000014_gene256	1.221e-168	543.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
LZS2_k127_943139_1	1382356.JQMP01000001_gene1144	4.649e-64	234.0	COG4177@1|root,COG4177@2|Bacteria,2G6D8@200795|Chloroflexi,27Z3V@189775|Thermomicrobia	189775|Thermomicrobia	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS2_k127_943139_0	1128421.JAGA01000002_gene1295	2.189e-101	336.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS2_k127_961_0	477974.Daud_0138	3.661e-43	177.0	COG2199@1|root,COG2206@1|root,COG3290@1|root,COG3829@1|root,COG4936@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4936@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,267B5@186807|Peptococcaceae	186801|Clostridia	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9
LZS2_k127_961_1	367299.JOEE01000003_gene2938	1.897e-17	86.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4FGAV@85021|Intrasporangiaceae	201174|Actinobacteria	K	Chemotaxis protein CheY	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
## 4194 queries scanned
## Total time (seconds): 71.86926484107971
## Rate: 58.36 q/s