## Sat Nov 16 07:59:03 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin12/LZS_2_bin.43.fa -m mmseqs --itype genome -o LZS_2_bin.43 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/LZS_2_bin.43 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
LZS2_k127_1004001_0	215803.DB30_5167	3.91e-30	128.0	COG0546@1|root,COG0546@2|Bacteria,1QX7M@1224|Proteobacteria,438Y4@68525|delta/epsilon subdivisions,2X43J@28221|Deltaproteobacteria,2YY61@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS2_k127_1004733_2	1123368.AUIS01000007_gene2719	5.708e-10	62.0	COG2906@1|root,COG2906@2|Bacteria,1NGGY@1224|Proteobacteria	1224|Proteobacteria	P	Bacterioferritin-associated ferredoxin	bfd	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
LZS2_k127_1004733_0	1121904.ARBP01000016_gene5270	1.736e-79	272.0	COG0300@1|root,COG0300@2|Bacteria,4NIAI@976|Bacteroidetes,47MJU@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
LZS2_k127_1004975_0	1120973.AQXL01000122_gene142	2.772e-170	542.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,277YV@186823|Alicyclobacillaceae	91061|Bacilli	I	Belongs to the thiolase family	pcaF	-	2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K02615	ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_1004975_1	1280689.AUJC01000001_gene2298	3.026e-25	119.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,36FXK@31979|Clostridiaceae	186801|Clostridia	L	DNA repair exonuclease	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
LZS2_k127_1004975_2	635013.TherJR_1988	4.13e-12	78.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes	1239|Firmicutes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
LZS2_k127_1008406_0	1379270.AUXF01000001_gene2615	1.108e-183	592.0	COG0587@1|root,COG0587@2|Bacteria,1ZU9R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS2_k127_1008406_1	5911.EAR96986	0.0005523	52.0	COG0457@1|root,KOG0660@1|root,KOG0660@2759|Eukaryota,KOG1840@2759|Eukaryota	2759|Eukaryota	C	determination of stomach left/right asymmetry	-	-	2.7.11.24,2.8.2.39	ko:K19603,ko:K22312	ko04657,map04657	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
LZS2_k127_1011392_0	32057.KB217480_gene8197	2.414e-19	95.0	COG0457@1|root,COG1357@1|root,COG0457@2|Bacteria,COG1357@2|Bacteria,1G1QI@1117|Cyanobacteria,1HJWQ@1161|Nostocales	1117|Cyanobacteria	K	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_1011392_1	997346.HMPREF9374_1802	9.223e-14	78.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,27B6R@186824|Thermoactinomycetaceae	91061|Bacilli	I	AMP-binding enzyme C-terminal domain	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS2_k127_1012331_0	203119.Cthe_2171	3.88e-184	612.0	COG1061@1|root,COG1061@2|Bacteria,1TRA8@1239|Firmicutes,2481H@186801|Clostridia,3WNCQ@541000|Ruminococcaceae	186801|Clostridia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
LZS2_k127_1039582_1	646529.Desaci_4468	1.432e-09	63.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,260R6@186807|Peptococcaceae	186801|Clostridia	C	NADH dehydrogenase	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
LZS2_k127_1039582_0	153721.MYP_4414	1.352e-59	218.0	COG1834@1|root,COG1834@2|Bacteria	2|Bacteria	E	dimethylargininase activity	-	GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Amidinotransf,Saccharop_dh_N
LZS2_k127_1047448_0	1123389.ATXJ01000018_gene982	0.0003294	53.0	COG2804@1|root,COG2804@2|Bacteria,1WIW9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilF	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
LZS2_k127_105950_0	317936.Nos7107_1979	1.716e-60	234.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1GIVF@1117|Cyanobacteria,1HRWB@1161|Nostocales	1117|Cyanobacteria	S	SPTR Tetratricopeptide repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
LZS2_k127_105950_3	243090.RB11578	2.874e-15	87.0	COG4848@1|root,COG4848@2|Bacteria,2J4H3@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0354 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1444
LZS2_k127_105950_2	886882.PPSC2_c3756	5.416e-24	109.0	2DPUV@1|root,333GC@2|Bacteria,1U4ZY@1239|Firmicutes,4IERW@91061|Bacilli,2705U@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_105950_1	56110.Oscil6304_5476	1.805e-57	207.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria,1HAYJ@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
LZS2_k127_1073531_0	44689.DDB0219761	1.194e-25	122.0	COG0457@1|root,COG2319@1|root,KOG1840@2759|Eukaryota,KOG3602@2759|Eukaryota,3XDRW@554915|Amoebozoa	554915|Amoebozoa	Z	Domain of unknown function (DUF4062)	-	-	-	ko:K19360	-	-	-	-	ko00000,ko03036	-	-	-	BRCT_2,DUF4062,TPR_12
LZS2_k127_107355_0	926561.KB900622_gene594	1.365e-93	318.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WAA8@53433|Halanaerobiales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS2_k127_107355_4	613026.HRAG_02015	1.946e-07	61.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	CP_0175	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF2786,DUF45,SprT-like
LZS2_k127_107355_2	588581.Cpap_1630	7.011e-35	140.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3WK4Z@541000|Ruminococcaceae	186801|Clostridia	H	adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
LZS2_k127_107355_1	1089553.Tph_c02040	3.073e-71	251.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,24AQ0@186801|Clostridia,42G1D@68295|Thermoanaerobacterales	186801|Clostridia	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
LZS2_k127_107355_3	329726.AM1_0885	6.018e-16	87.0	COG3184@1|root,COG3184@2|Bacteria,1G97G@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K09924	-	-	-	-	ko00000	-	-	-	DUF2059
LZS2_k127_1074394_0	929556.Solca_1398	2.783e-87	310.0	COG1524@1|root,COG1524@2|Bacteria,4NE94@976|Bacteroidetes,1IP8D@117747|Sphingobacteriia	976|Bacteroidetes	P	type I phosphodiesterase nucleotide pyrophosphatase	pafA	GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_1074394_1	748449.Halha_0427	6.926e-39	151.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WAIG@53433|Halanaerobiales	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS2_k127_1075261_0	1206732.BAGD01000127_gene5577	6.658e-127	426.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4FXHJ@85025|Nocardiaceae	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS2_k127_1075261_1	314230.DSM3645_16920	6.626e-10	70.0	COG4886@1|root,COG4886@2|Bacteria,2J0RN@203682|Planctomycetes	203682|Planctomycetes	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
LZS2_k127_1098263_0	247490.KSU1_C0643	2.716e-127	419.0	COG3696@1|root,COG3696@2|Bacteria,2IY1K@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
LZS2_k127_1111175_1	1319815.HMPREF0202_01032	1.926e-69	249.0	COG4819@1|root,COG4819@2|Bacteria,3790A@32066|Fusobacteria	32066|Fusobacteria	E	Ethanolamine utilisation protein EutA	eutA	-	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
LZS2_k127_1111175_2	1121472.AQWN01000001_gene56	1.481e-53	198.0	COG4302@1|root,COG4302@2|Bacteria,1TSZM@1239|Firmicutes,24A5Y@186801|Clostridia,260ZI@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the EutC family	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
LZS2_k127_1111175_0	1121422.AUMW01000018_gene1871	1.091e-173	556.0	COG4303@1|root,COG4303@2|Bacteria,1TP15@1239|Firmicutes,248P5@186801|Clostridia,260JB@186807|Peptococcaceae	186801|Clostridia	E	PFAM Ethanolamine ammonia lyase large subunit	eutB	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
LZS2_k127_1111177_3	565034.BHWA1_01798	4.322e-24	108.0	COG0457@1|root,COG0457@2|Bacteria	565034.BHWA1_01798|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1111177_2	742727.HMPREF9447_03335	2.785e-46	176.0	COG1670@1|root,COG1670@2|Bacteria,4NP1T@976|Bacteroidetes,2FUDJ@200643|Bacteroidia,4AS3V@815|Bacteroidaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_1111177_0	1128421.JAGA01000002_gene1751	3.209e-152	493.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
LZS2_k127_1111177_1	926561.KB900617_gene1429	7.071e-73	259.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WAE4@53433|Halanaerobiales	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
LZS2_k127_1119038_1	1122599.AUGR01000005_gene1857	5.793e-20	97.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,1RNXI@1236|Gammaproteobacteria,1XINH@135619|Oceanospirillales	135619|Oceanospirillales	T	response regulator	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_1119038_0	682795.AciX8_4094	2.813e-120	392.0	COG3220@1|root,COG3220@2|Bacteria,3Y35V@57723|Acidobacteria,2JHT9@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
LZS2_k127_1119038_2	278963.ATWD01000001_gene4049	1.559e-06	53.0	COG3219@1|root,COG3219@2|Bacteria,3Y4AB@57723|Acidobacteria,2JJ3J@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
LZS2_k127_1122575_1	1321820.HMPREF1983_01278	1.404e-21	104.0	COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,4HCIJ@91061|Bacilli,3WEGW@539002|Bacillales incertae sedis	91061|Bacilli	E	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
LZS2_k127_1122575_0	748449.Halha_1896	1.217e-42	168.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3WBPR@53433|Halanaerobiales	186801|Clostridia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
LZS2_k127_1122575_2	351160.RRC456	6.442e-05	54.0	COG3263@1|root,arCOG01962@2157|Archaea	2157|Archaea	P	Sodium hydrogen exchanger	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger
LZS2_k127_1130597_0	1242864.D187_008408	8.122e-134	431.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42PKM@68525|delta/epsilon subdivisions,2WJCP@28221|Deltaproteobacteria,2YUCG@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
LZS2_k127_1130597_1	697282.Mettu_3272	4.345e-38	155.0	COG0457@1|root,COG0457@2|Bacteria,1MWRF@1224|Proteobacteria,1S182@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Pfam Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_7
LZS2_k127_1133188_2	313612.L8106_17422	1.716e-08	58.0	COG2304@1|root,COG2304@2|Bacteria,1G21D@1117|Cyanobacteria,1H929@1150|Oscillatoriales	1117|Cyanobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1133188_1	1502851.FG93_00529	1.124e-107	357.0	COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,2TVAB@28211|Alphaproteobacteria,3JUMP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
LZS2_k127_1133188_0	926562.Oweho_0039	5.554e-112	370.0	COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,1HXRG@117743|Flavobacteriia	976|Bacteroidetes	U	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS2_k127_1133536_0	595460.RRSWK_03574	3.899e-123	419.0	COG1960@1|root,COG1960@2|Bacteria,2IXZJ@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_1133536_1	118161.KB235922_gene4397	6.493e-10	63.0	2E31B@1|root,32Y1Q@2|Bacteria,1G8Y8@1117|Cyanobacteria,3VKG5@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_116215_1	323261.Noc_2124	9.413e-78	266.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1WWET@135613|Chromatiales	135613|Chromatiales	E	PFAM Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_116215_0	926550.CLDAP_01290	5.058e-110	368.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi	200795|Chloroflexi	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_1165824_1	272134.KB731324_gene2238	1.255e-08	66.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1H8X5@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_1165824_0	1121434.AULY01000009_gene2034	6.059e-19	97.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,42R2X@68525|delta/epsilon subdivisions,2WMU1@28221|Deltaproteobacteria,2MAZ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS2_k127_1187907_0	1396141.BATP01000056_gene3118	4.637e-40	158.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,2IWN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_1187907_1	700508.D174_02080	1.181e-29	136.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,233BZ@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_1198184_0	1304878.AUGD01000002_gene1616	0.0002886	50.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,3JTIK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_7,TPR_8
LZS2_k127_1251763_1	580332.Slit_2546	9.254e-34	134.0	arCOG09571@1|root,32S48@2|Bacteria,1R12B@1224|Proteobacteria,2W64T@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1251763_3	1254432.SCE1572_49350	8.546e-25	109.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
LZS2_k127_1251763_2	1123256.KB907941_gene118	1.438e-28	118.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,1S8YH@1236|Gammaproteobacteria,1X7HD@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulators	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
LZS2_k127_1272963_1	1237149.C900_02025	7.401e-27	117.0	29E77@1|root,30157@2|Bacteria,4NPIN@976|Bacteroidetes,47QWY@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1272963_0	485913.Krac_11738	2.978e-67	235.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_128483_9	292563.Cyast_2176	9.133e-14	72.0	COG0257@1|root,COG0257@2|Bacteria,1GAEI@1117|Cyanobacteria	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
LZS2_k127_128483_5	1089552.KI911559_gene2994	9.66e-43	159.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,2JS7G@204441|Rhodospirillales	204441|Rhodospirillales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
LZS2_k127_128483_2	197221.22293825	1.732e-57	203.0	COG0100@1|root,COG0100@2|Bacteria,1G4Z1@1117|Cyanobacteria	1117|Cyanobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
LZS2_k127_128483_1	1195236.CTER_2769	5.81e-69	239.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
LZS2_k127_128483_0	941824.TCEL_01077	1.401e-90	310.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,36ESF@31979|Clostridiaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
LZS2_k127_128483_7	1541065.JRFE01000025_gene1910	1.074e-26	114.0	COG0203@1|root,COG0203@2|Bacteria,1G6JN@1117|Cyanobacteria,3VJT9@52604|Pleurocapsales	1117|Cyanobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
LZS2_k127_128483_4	429009.Adeg_1494	4.05e-48	182.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,42FMH@68295|Thermoanaerobacterales	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
LZS2_k127_128483_3	393595.ABO_0576	6.428e-57	202.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1XJIQ@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
LZS2_k127_128483_6	1123500.ATUU01000002_gene665	1.444e-39	150.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli,4AXP7@81850|Leuconostocaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS2_k127_128483_8	1122605.KB893634_gene4208	1.052e-17	98.0	COG0457@1|root,COG0457@2|Bacteria,4NI5H@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
LZS2_k127_1291943_0	530564.Psta_0057	1.82e-07	59.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,2IX09@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1080,FGE-sulfatase,LRR_6,Laminin_G_3,PEGA,Pkinase
LZS2_k127_1291943_1	720554.Clocl_0760	1.018e-06	58.0	28PFH@1|root,2ZC6N@2|Bacteria,1UZY8@1239|Firmicutes,24FCF@186801|Clostridia,3WM1F@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4272)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4272
LZS2_k127_1302177_5	886293.Sinac_2520	1.284e-15	81.0	COG2217@1|root,COG2217@2|Bacteria,2IXAD@203682|Planctomycetes	203682|Planctomycetes	P	heavy metal translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
LZS2_k127_1302177_4	107635.AZUO01000001_gene1903	3.583e-20	102.0	COG0457@1|root,COG0457@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria,36ZXV@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_1302177_2	1142394.PSMK_30670	1.727e-52	192.0	COG1975@1|root,COG1975@2|Bacteria,2IXRN@203682|Planctomycetes	203682|Planctomycetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
LZS2_k127_1302177_6	264462.Bd2635	2.756e-10	63.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,43BHQ@68525|delta/epsilon subdivisions,2MTVP@213481|Bdellovibrionales,2X6W7@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	XdhC Rossmann domain	pcmU	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
LZS2_k127_1302177_0	862908.BMS_2856	3.455e-245	782.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,43C3C@68525|delta/epsilon subdivisions,2MTI8@213481|Bdellovibrionales,2X7DZ@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Xanthine dehydrogenase	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
LZS2_k127_1302177_1	862908.BMS_2857	6.668e-113	383.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,43E4Q@68525|delta/epsilon subdivisions,2MTP3@213481|Bdellovibrionales,2X7E4@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	CO dehydrogenase flavoprotein C-terminal domain	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
LZS2_k127_1302177_3	1220534.B655_2316	5.078e-36	143.0	COG5483@1|root,arCOG00723@2157|Archaea,2XYZG@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
LZS2_k127_130366_1	1128427.KB904821_gene1245	5.161e-27	114.0	COG0745@1|root,COG0745@2|Bacteria	1128427.KB904821_gene1245|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_130366_2	1144305.PMI02_02268	1.588e-12	80.0	COG0745@1|root,COG0784@1|root,COG2199@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1NC9X@1224|Proteobacteria,2TW49@28211|Alphaproteobacteria,2KEAB@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
LZS2_k127_130366_0	443598.AUFA01000024_gene1606	1.526e-29	135.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQX3@28211|Alphaproteobacteria,3JR5W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Pkinase
LZS2_k127_1304536_0	1280688.AUJB01000004_gene80	2.018e-36	156.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3NIDJ@46205|Pseudobutyrivibrio	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_1309146_1	28072.Nos7524_2080	1.96e-127	414.0	COG3033@1|root,COG3033@2|Bacteria,1G33V@1117|Cyanobacteria,1HQEM@1161|Nostocales	1117|Cyanobacteria	E	Beta-eliminating lyase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS2_k127_1309146_0	314262.MED193_07793	7.881e-267	830.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2TSXZ@28211|Alphaproteobacteria,2P18D@2433|Roseobacter	28211|Alphaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
LZS2_k127_1309146_5	111781.Lepto7376_1356	6.306e-16	82.0	COG1733@1|root,COG1733@2|Bacteria,1G7DW@1117|Cyanobacteria,1HBWZ@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
LZS2_k127_1309146_3	661478.OP10G_3212	2.891e-49	180.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
LZS2_k127_1309146_4	1121904.ARBP01000003_gene6437	1.491e-32	130.0	COG2223@1|root,COG2223@2|Bacteria,4NETE@976|Bacteroidetes	976|Bacteroidetes	P	Pfam Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
LZS2_k127_1309146_6	797303.Natpe_0090	5.35e-05	54.0	COG0589@1|root,arCOG02053@2157|Archaea,2XX03@28890|Euryarchaeota,23VE3@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_1309146_2	234267.Acid_2401	4.609e-57	208.0	COG1398@1|root,COG1398@2|Bacteria,3Y6GE@57723|Acidobacteria	57723|Acidobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS2_k127_1314097_2	57918.XP_004287248.1	1.654e-09	68.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37ICC@33090|Viridiplantae,3G9ZF@35493|Streptophyta,4JMQP@91835|fabids	35493|Streptophyta	S	F-box LRR-repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,LRR_6,LRR_8
LZS2_k127_1314097_0	330214.NIDE1155	4.721e-60	225.0	COG0477@1|root,COG2814@2|Bacteria,3J171@40117|Nitrospirae	40117|Nitrospirae	EGP	Sugar (and other) transporter	-	-	-	ko:K08178	-	-	-	-	ko00000,ko02000	2.A.1.12	-	-	MFS_1
LZS2_k127_1314097_1	37919.EP51_02790	3.849e-24	112.0	COG0515@1|root,COG3055@1|root,COG0515@2|Bacteria,COG3055@2|Bacteria,2HEN9@201174|Actinobacteria,4FVW7@85025|Nocardiaceae	201174|Actinobacteria	KLT	Galactose oxidase, central domain	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Kelch_1,Pkinase
LZS2_k127_1319426_0	1316927.ATKI01000032_gene4858	1.809e-83	293.0	COG1819@1|root,COG1819@2|Bacteria,1PVC3@1224|Proteobacteria,1RVQW@1236|Gammaproteobacteria,1YU9N@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	ko:K18101	ko02024,ko02025,map02024,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT1	-	Glyco_transf_28
LZS2_k127_1319426_1	1089550.ATTH01000001_gene1565	1.051e-42	163.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1FK5D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
LZS2_k127_1331957_2	1121896.JMLU01000001_gene1188	3.906e-07	55.0	COG3695@1|root,COG3695@2|Bacteria,4NQ34@976|Bacteroidetes,1I2Y7@117743|Flavobacteriia,2NWQV@237|Flavobacterium	976|Bacteroidetes	L	Cysteine methyltransferase	ogt	-	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
LZS2_k127_1331957_0	886293.Sinac_0609	2.799e-58	214.0	COG1835@1|root,COG1835@2|Bacteria,2J0W8@203682|Planctomycetes	2|Bacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
LZS2_k127_1331957_1	886293.Sinac_3025	4.259e-34	136.0	COG1186@1|root,COG1186@2|Bacteria,2J05G@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
LZS2_k127_1336207_1	1157490.EL26_05845	1.052e-41	164.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,2786X@186823|Alicyclobacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
LZS2_k127_1336207_2	1237149.C900_00363	2.399e-27	121.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,4NFWN@976|Bacteroidetes,47QVZ@768503|Cytophagia	976|Bacteroidetes	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
LZS2_k127_1336207_0	268407.PWYN_19290	2.307e-50	184.0	COG1670@1|root,COG1670@2|Bacteria,1V4ZB@1239|Firmicutes,4HHG0@91061|Bacilli,274T0@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
LZS2_k127_1337279_0	1476583.DEIPH_ctg032orf0055	2.807e-39	151.0	COG0732@1|root,COG0732@2|Bacteria,1WKUF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
LZS2_k127_1337279_1	1028800.RG540_CH03810	0.0001228	54.0	COG2865@1|root,COG2865@2|Bacteria,1RD2Z@1224|Proteobacteria,2UJC9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	PFAM AAA-4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2
LZS2_k127_1351579_2	883112.HMPREF9707_00676	2.059e-34	143.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli,27DC8@186827|Aerococcaceae	91061|Bacilli	J	ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
LZS2_k127_1351579_1	1185876.BN8_04306	1.076e-126	419.0	COG0477@1|root,COG2814@2|Bacteria,4NE09@976|Bacteroidetes,47MBV@768503|Cytophagia	976|Bacteroidetes	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
LZS2_k127_1351579_0	796606.BMMGA3_00550	5.3e-199	645.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_1351579_3	1042163.BRLA_c004110	3.724e-08	63.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,4HBGP@91061|Bacilli,273GT@186822|Paenibacillaceae	91061|Bacilli	H	ThiF family	thiF	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
LZS2_k127_1360273_0	317619.ANKN01000190_gene602	5.669e-11	73.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1MKWK@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_1365254_2	340.xcc-b100_0962	1.586e-16	91.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,1RMDX@1236|Gammaproteobacteria,1X2YK@135614|Xanthomonadales	135614|Xanthomonadales	S	von willebrand factor, type a	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
LZS2_k127_1365254_1	157783.LK03_17640	1.689e-20	93.0	2DNMU@1|root,32Y5V@2|Bacteria,1NDWM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1365254_0	1137271.AZUM01000006_gene564	1.562e-177	573.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4DY8C@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
LZS2_k127_1368589_2	478741.JAFS01000001_gene1051	4.032e-51	186.0	COG0842@1|root,COG0842@2|Bacteria,46UQ0@74201|Verrucomicrobia,37GJ6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS2_k127_1368589_3	1183438.GKIL_3492	1.439e-19	93.0	2EG6D@1|root,339Y8@2|Bacteria,1GF7B@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1368589_1	118166.JH976537_gene3039	1.414e-62	228.0	COG0393@1|root,COG0393@2|Bacteria,1GCDH@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS2_k127_1368589_0	1183438.GKIL_3494	8.698e-132	426.0	COG0393@1|root,COG0393@2|Bacteria,1GC92@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS2_k127_1375034_1	118161.KB235922_gene518	3.93e-106	368.0	COG0747@1|root,COG0747@2|Bacteria,1G0KJ@1117|Cyanobacteria,3VHWN@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_1375034_0	111780.Sta7437_3321	1.238e-116	402.0	COG0747@1|root,COG0747@2|Bacteria,1G0KJ@1117|Cyanobacteria,3VHWN@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_1379955_1	1379698.RBG1_1C00001G0634	6.617e-34	137.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
LZS2_k127_1379955_0	525904.Tter_0422	7.091e-147	484.0	COG0114@1|root,COG0114@2|Bacteria,2NS3X@2323|unclassified Bacteria	2|Bacteria	C	Fumarase C C-terminus	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS2_k127_1379955_3	326427.Cagg_3085	3.884e-17	94.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,375PN@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS2_k127_1379955_2	935948.KE386494_gene336	1.789e-32	142.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,42EM4@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS2_k127_1382121_2	1122223.KB890687_gene2915	0.0001658	50.0	COG1413@1|root,COG5330@1|root,COG1413@2|Bacteria,COG5330@2|Bacteria,1WMZN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Leucine rich repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_1382121_0	65393.PCC7424_5070	4.525e-52	192.0	COG2197@1|root,COG2197@2|Bacteria,1G1P0@1117|Cyanobacteria,3KFVP@43988|Cyanothece	1117|Cyanobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_1382121_1	1165094.RINTHH_22670	1.475e-06	55.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1GHD5@1117|Cyanobacteria,1HUA2@1161|Nostocales	1117|Cyanobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_1382827_1	756272.Plabr_4533	9.154e-90	310.0	COG0508@1|root,COG0508@2|Bacteria,2IY0W@203682|Planctomycetes	203682|Planctomycetes	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS2_k127_1382827_0	1123242.JH636434_gene3888	2.24e-134	443.0	COG1249@1|root,COG1249@2|Bacteria,2IX5H@203682|Planctomycetes	203682|Planctomycetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS2_k127_1405983_3	1128111.HMPREF0870_00588	1.743e-21	96.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4H2AC@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS2_k127_1405983_0	671143.DAMO_2177	8.567e-78	275.0	COG0787@1|root,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
LZS2_k127_1405983_2	864702.OsccyDRAFT_2257	4.19e-28	115.0	COG0776@1|root,COG0776@2|Bacteria,1G8Y4@1117|Cyanobacteria,1HFWP@1150|Oscillatoriales	1117|Cyanobacteria	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
LZS2_k127_1405983_1	237368.SCABRO_02723	3.178e-53	193.0	COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,2IZ7A@203682|Planctomycetes	203682|Planctomycetes	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep
LZS2_k127_1423402_0	1183438.GKIL_1503	2.592e-47	179.0	COG0745@1|root,COG0745@2|Bacteria,1G1DH@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K11521	ko02020,map02020	M00465	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_1423402_1	321332.CYB_1354	2.404e-46	176.0	COG2197@1|root,COG2197@2|Bacteria,1GHXP@1117|Cyanobacteria,1GZT1@1129|Synechococcus	1117|Cyanobacteria	T	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_1435638_2	314278.NB231_14243	3.24e-08	57.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1WYFE@135613|Chromatiales	135613|Chromatiales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_1435638_0	1123288.SOV_4c00290	1.352e-59	218.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4H25A@909932|Negativicutes	909932|Negativicutes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_1435638_1	1536775.H70737_11845	2e-13	76.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,4HHE6@91061|Bacilli,26YR8@186822|Paenibacillaceae	91061|Bacilli	S	Domain in cystathionine beta-synthase and other proteins.	ylbB	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS2_k127_1435638_3	1280664.AUIX01000001_gene621	0.0006466	48.0	COG1413@1|root,COG1413@2|Bacteria,1VX4R@1239|Firmicutes,2523I@186801|Clostridia,4BYSK@830|Butyrivibrio	186801|Clostridia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_1442206_4	1268635.Loa_00767	1.13e-06	52.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,1JEZI@118969|Legionellales	118969|Legionellales	J	structural constituent of ribosome	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
LZS2_k127_1442206_2	395961.Cyan7425_3403	5.856e-37	149.0	COG0368@1|root,COG0368@2|Bacteria,1G0DC@1117|Cyanobacteria,3KHD8@43988|Cyanothece	1117|Cyanobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
LZS2_k127_1442206_3	1157490.EL26_07600	4.111e-11	75.0	COG0457@1|root,COG0457@2|Bacteria,1VEYH@1239|Firmicutes,4HTC0@91061|Bacilli,2793G@186823|Alicyclobacillaceae	91061|Bacilli	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1442206_0	1196324.A374_02279	1.501e-79	273.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli	91061|Bacilli	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
LZS2_k127_1442206_1	195250.CM001776_gene2304	2.919e-68	239.0	COG0216@1|root,COG0216@2|Bacteria,1FZY4@1117|Cyanobacteria,1GYAU@1129|Synechococcus	1117|Cyanobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS2_k127_144255_1	1122915.AUGY01000021_gene6644	1.674e-57	211.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,4HC7I@91061|Bacilli,26UP7@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function DUF111	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
LZS2_k127_144255_0	1449126.JQKL01000057_gene2246	2.301e-88	305.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,268I6@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
LZS2_k127_144255_2	1336234.JAGN01000001_gene1226	1.39e-53	194.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli,27FCV@186828|Carnobacteriaceae	91061|Bacilli	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15680	Guanylate_kin
LZS2_k127_1445014_0	525909.Afer_1376	1.268e-88	299.0	COG0208@1|root,COG0208@2|Bacteria,2IC1M@201174|Actinobacteria,4CNJX@84992|Acidimicrobiia	84992|Acidimicrobiia	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
LZS2_k127_1445014_1	215803.DB30_8095	2.571e-34	138.0	2E3R3@1|root,32YNW@2|Bacteria,1N9P4@1224|Proteobacteria,432YQ@68525|delta/epsilon subdivisions,2WXU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1445014_3	671143.DAMO_0496	0.0005777	51.0	COG0810@1|root,COG0810@2|Bacteria,2NQ3G@2323|unclassified Bacteria	2|Bacteria	M	TonB C terminal	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_2,TonB_C
LZS2_k127_1445014_2	33876.JNXY01000042_gene3828	3.799e-10	61.0	COG4251@1|root,COG4251@2|Bacteria,2H241@201174|Actinobacteria,4DIES@85008|Micromonosporales	201174|Actinobacteria	T	CHASE domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA
LZS2_k127_1446716_0	1449126.JQKL01000035_gene2174	4.497e-43	173.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,2683T@186813|unclassified Clostridiales	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_1446716_1	886293.Sinac_4353	6.372e-34	134.0	2A8GS@1|root,30XIR@2|Bacteria,2J2JC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1447794_4	114615.BRADO7054	3.718e-06	57.0	COG0500@1|root,COG0500@2|Bacteria,1R7BN@1224|Proteobacteria,2U50R@28211|Alphaproteobacteria,3JUW7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
LZS2_k127_1447794_0	1121405.dsmv_3545	5.013e-54	192.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2MJ5F@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
LZS2_k127_1447794_2	4006.Lus10008036	4.147e-21	105.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37ICC@33090|Viridiplantae,3G9ZF@35493|Streptophyta,4JMQP@91835|fabids	35493|Streptophyta	S	F-box LRR-repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,LRR_6,LRR_8
LZS2_k127_1447794_3	1027273.GZ77_21225	1.206e-07	59.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,1S4IJ@1236|Gammaproteobacteria,1XM1E@135619|Oceanospirillales	135619|Oceanospirillales	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
LZS2_k127_1447794_1	1210884.HG799463_gene10329	9.062e-30	120.0	COG4680@1|root,COG4680@2|Bacteria,2J3QG@203682|Planctomycetes	203682|Planctomycetes	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
LZS2_k127_1462187_1	2325.TKV_c10450	5.068e-49	184.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,42FXF@68295|Thermoanaerobacterales	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
LZS2_k127_1462187_0	240015.ACP_0842	1.06e-211	665.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,3Y2RE@57723|Acidobacteria,2JHM7@204432|Acidobacteriia	204432|Acidobacteriia	G	Maltogenic Amylase, C-terminal domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
LZS2_k127_1466214_0	1122169.AREN01000001_gene979	2.048e-28	126.0	COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,1RYEY@1236|Gammaproteobacteria,1JCHK@118969|Legionellales	118969|Legionellales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
LZS2_k127_1469577_0	1123320.KB889664_gene965	1.989e-36	156.0	COG0515@1|root,COG0515@2|Bacteria,2IA1X@201174|Actinobacteria	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_1478359_1	1123248.KB893315_gene3035	6.178e-20	102.0	2CEJ5@1|root,2Z7RK@2|Bacteria,4NGWQ@976|Bacteroidetes,1IS7V@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
LZS2_k127_1478359_0	861299.J421_4066	1.653e-63	231.0	COG0515@1|root,COG0515@2|Bacteria,1ZTGA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_1482349_1	1487953.JMKF01000056_gene4464	1.305e-08	59.0	COG3695@1|root,COG3695@2|Bacteria,1G82G@1117|Cyanobacteria,1HCND@1150|Oscillatoriales	1117|Cyanobacteria	L	Methylated dna-protein cysteine methyltransferase	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
LZS2_k127_1482349_0	1380391.JIAS01000015_gene42	2.297e-78	284.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
LZS2_k127_1488624_5	471855.Shel_22540	5.796e-06	58.0	COG3023@1|root,COG3023@2|Bacteria,2HUP0@201174|Actinobacteria,4CV90@84998|Coriobacteriia	84998|Coriobacteriia	V	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
LZS2_k127_1488624_1	221288.JH992901_gene4260	1.584e-98	335.0	COG0482@1|root,COG0482@2|Bacteria,1G21J@1117|Cyanobacteria,1JK5G@1189|Stigonemataceae	1117|Cyanobacteria	J	tRNA methyl transferase	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
LZS2_k127_1488624_3	63737.Npun_R1867	1.814e-19	102.0	COG0457@1|root,COG0457@2|Bacteria,1G39E@1117|Cyanobacteria,1HQX3@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
LZS2_k127_1488624_0	555079.Toce_0099	4.159e-275	888.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
LZS2_k127_1488624_4	983917.RGE_24270	2.028e-06	60.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,1KJ83@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	peptidylprolyl isomerase	cbf2	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N_3
LZS2_k127_1488624_2	32057.KB217478_gene5133	8.685e-37	151.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2
LZS2_k127_148954_0	1407650.BAUB01000009_gene1816	2.139e-204	668.0	COG1200@1|root,COG1200@2|Bacteria,1G17H@1117|Cyanobacteria,1GZ2C@1129|Synechococcus	1117|Cyanobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
LZS2_k127_1491307_0	1353531.AZNX01000008_gene644	2.68e-89	300.0	COG2227@1|root,COG2227@2|Bacteria,1QWVZ@1224|Proteobacteria,2TZDN@28211|Alphaproteobacteria,4BP21@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_1491307_1	28229.ND2E_1534	2.214e-16	89.0	COG1226@1|root,32Y28@2|Bacteria,1NEAT@1224|Proteobacteria,1S588@1236|Gammaproteobacteria,2Q6SK@267889|Colwelliaceae	1236|Gammaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
LZS2_k127_1501027_0	1173264.KI913949_gene213	2.182e-71	249.0	COG0143@1|root,COG0143@2|Bacteria,1G1RR@1117|Cyanobacteria,1H70W@1150|Oscillatoriales	1117|Cyanobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
LZS2_k127_1501027_1	111780.Sta7437_3088	1.26e-40	168.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,1G10B@1117|Cyanobacteria,3VJ4K@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
LZS2_k127_1501027_2	926569.ANT_15160	5.643e-27	126.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
LZS2_k127_1506240_0	1541065.JRFE01000001_gene2582	1.376e-97	331.0	COG1301@1|root,COG1301@2|Bacteria,1G32C@1117|Cyanobacteria,3VN2Y@52604|Pleurocapsales	1117|Cyanobacteria	C	Sodium:dicarboxylate symporter family	-	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
LZS2_k127_1506240_2	4098.XP_009618376.1	2.088e-13	83.0	COG2267@1|root,KOG1455@2759|Eukaryota,37IA3@33090|Viridiplantae,3G92D@35493|Streptophyta,44PXK@71274|asterids	35493|Streptophyta	I	Serine aminopeptidase, S33	-	-	3.1.1.23	ko:K01054	ko00561,ko01100,ko04714,ko04723,ko04923,map00561,map01100,map04714,map04723,map04923	M00098	R01351	RC00020,RC00041	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Hydrolase_4
LZS2_k127_1506240_1	1382305.AZUC01000045_gene1217	6.253e-48	178.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli,26I3X@186818|Planococcaceae	91061|Bacilli	M	Substrate binding domain of ABC-type glycine betaine transport system	proWX	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
LZS2_k127_1508544_1	1183438.GKIL_4343	3.839e-40	160.0	COG0248@1|root,COG0248@2|Bacteria,1FZZC@1117|Cyanobacteria	1117|Cyanobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
LZS2_k127_1508544_0	595460.RRSWK_01104	1.576e-41	159.0	COG1232@1|root,COG1232@2|Bacteria,2IWT1@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS2_k127_15097_2	56107.Cylst_4280	2.596e-17	89.0	COG0457@1|root,COG0457@2|Bacteria,1G0N0@1117|Cyanobacteria,1HQK0@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_15097_0	756272.Plabr_3129	1.754e-135	448.0	COG1680@1|root,COG1680@2|Bacteria,2IWSU@203682|Planctomycetes	203682|Planctomycetes	MV	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
LZS2_k127_15097_1	232348.ADXL01000033_gene1411	2.085e-17	83.0	COG0393@1|root,COG0393@2|Bacteria,1G7AD@1117|Cyanobacteria,1H2BY@1129|Synechococcus	1117|Cyanobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS2_k127_151526_0	574087.Acear_1557	1.78e-71	252.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,3WAPD@53433|Halanaerobiales	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
LZS2_k127_151526_1	1304880.JAGB01000003_gene1316	0.000115	54.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_1517090_0	349521.HCH_06378	7.711e-12	80.0	COG0433@1|root,COG0433@2|Bacteria,1N28R@1224|Proteobacteria,1T43Q@1236|Gammaproteobacteria,1XQBU@135619|Oceanospirillales	1224|Proteobacteria	S	COG0433 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
LZS2_k127_1526863_0	396588.Tgr7_0799	9.583e-127	420.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,1RMNF@1236|Gammaproteobacteria,1WXAG@135613|Chromatiales	135613|Chromatiales	E	PFAM sodium alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
LZS2_k127_153899_1	1121403.AUCV01000001_gene815	1.973e-28	117.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,2MKNN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
LZS2_k127_153899_0	1260251.SPISAL_05830	2.081e-177	571.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1WWT9@135613|Chromatiales	135613|Chromatiales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS2_k127_1539304_1	1094508.Tsac_0539	2.09e-11	65.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,42F7T@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase class V	csd2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS2_k127_1539304_0	251221.35211082	6.532e-44	183.0	COG0741@1|root,COG1729@1|root,COG4105@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,1G1HC@1117|Cyanobacteria	1117|Cyanobacteria	M	Soluble lytic murein	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
LZS2_k127_1539736_1	580332.Slit_1705	2.966e-10	72.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2WD6M@28216|Betaproteobacteria,44WJD@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
LZS2_k127_1539736_0	1192034.CAP_6830	2.291e-34	138.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_1540384_3	1121382.JQKG01000006_gene3496	5.546e-35	136.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
LZS2_k127_1540384_4	1286093.C266_24583	8.707e-17	82.0	COG0369@1|root,COG1145@1|root,COG0369@2|Bacteria,COG1145@2|Bacteria,1NCKQ@1224|Proteobacteria,2VIZE@28216|Betaproteobacteria,1K05A@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Benzoyl-CoA oxygenase	boxA	-	1.14.13.208,1.18.1.2,1.19.1.1	ko:K00528,ko:K02641,ko:K15511	ko00195,ko00362,ko01100,map00195,map00362,map01100	-	R09555,R10159	RC01739	ko00000,ko00001,ko00194,ko01000	-	-	-	FAD_binding_6,Fer4,NAD_binding_1
LZS2_k127_1540384_2	420324.KI911965_gene565	2.456e-36	148.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2TUTT@28211|Alphaproteobacteria,1JUPH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Phenylacetic acid catabolic protein	-	-	-	-	-	-	-	-	-	-	-	-	PaaA_PaaC
LZS2_k127_1540384_0	1123355.JHYO01000012_gene728	1.516e-110	363.0	COG3396@1|root,COG3396@2|Bacteria,1R8B1@1224|Proteobacteria,2U4FX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phenylacetic acid catabolic protein	-	-	-	-	-	-	-	-	-	-	-	-	PaaA_PaaC
LZS2_k127_1540384_1	595536.ADVE02000001_gene697	1.599e-73	253.0	COG0288@1|root,COG0288@2|Bacteria,1MV1U@1224|Proteobacteria,2VEYE@28211|Alphaproteobacteria,36YBN@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Carbonic anhydrase	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
LZS2_k127_154588_1	240016.ABIZ01000001_gene675	1.431e-124	413.0	COG2230@1|root,COG2230@2|Bacteria,46SMA@74201|Verrucomicrobia,2IVKD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS
LZS2_k127_154588_3	240016.ABIZ01000001_gene673	1.292e-54	201.0	COG3752@1|root,COG3752@2|Bacteria,46T0R@74201|Verrucomicrobia,2IW2F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
LZS2_k127_154588_2	497964.CfE428DRAFT_5336	5.985e-115	381.0	COG2230@1|root,COG2230@2|Bacteria,46TH2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS2_k127_154588_0	1232410.KI421428_gene1065	1.514e-161	518.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria,43TW9@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
LZS2_k127_1547226_0	632292.Calhy_1377	3.454e-298	933.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,42F4D@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
LZS2_k127_1547226_1	443144.GM21_2706	0.0007563	44.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
LZS2_k127_1557563_1	313612.L8106_30465	2.182e-87	297.0	COG0714@1|root,COG0714@2|Bacteria,1G1CG@1117|Cyanobacteria,1H70V@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_1557563_0	449447.MAE_42730	3.329e-112	367.0	COG0752@1|root,COG0752@2|Bacteria,1G097@1117|Cyanobacteria	1117|Cyanobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
LZS2_k127_1560862_3	13689.BV96_04132	2.221e-06	60.0	COG3843@1|root,COG3843@2|Bacteria,1MU0S@1224|Proteobacteria,2TSP8@28211|Alphaproteobacteria,2K23N@204457|Sphingomonadales	204457|Sphingomonadales	U	Type IV secretory pathway VirD2	-	-	-	-	-	-	-	-	-	-	-	-	DUF3363
LZS2_k127_1560862_1	1500890.JQNL01000001_gene2542	1.595e-28	133.0	COG3505@1|root,COG3505@2|Bacteria,1MV1G@1224|Proteobacteria,1RNF5@1236|Gammaproteobacteria,1X4R6@135614|Xanthomonadales	135614|Xanthomonadales	U	Type IV secretory pathway, VirD4	-	-	-	-	-	-	-	-	-	-	-	-	T4SS-DNA_transf
LZS2_k127_1560862_4	32057.KB217478_gene3334	1.257e-05	56.0	COG2214@1|root,COG2214@2|Bacteria,1G9HQ@1117|Cyanobacteria,1HNMF@1161|Nostocales	1117|Cyanobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_1,TPR_2
LZS2_k127_1560862_0	118173.KB235910_gene4780	1.617e-67	252.0	COG0775@1|root,COG4249@1|root,COG0775@2|Bacteria,COG4249@2|Bacteria,1GQV4@1117|Cyanobacteria,1HI1U@1150|Oscillatoriales	1117|Cyanobacteria	F	GUN4-like	-	-	-	-	-	-	-	-	-	-	-	-	GUN4
LZS2_k127_1560862_2	391008.Smal_1973	1.689e-18	100.0	COG0457@1|root,COG0457@2|Bacteria	391008.Smal_1973|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1561254_1	1379698.RBG1_1C00001G0715	3.005e-68	235.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
LZS2_k127_1561254_0	203124.Tery_2398	4.37e-110	365.0	COG1304@1|root,COG1304@2|Bacteria,1G32Y@1117|Cyanobacteria,1HA70@1150|Oscillatoriales	1117|Cyanobacteria	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid	lldD	-	1.1.2.3,1.1.3.46	ko:K00101,ko:K16422	ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130	-	R00196,R06633	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
LZS2_k127_1563181_1	868595.Desca_0882	1.158e-67	236.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,261FK@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS2_k127_1563181_0	386456.JQKN01000008_gene1360	1.674e-132	431.0	COG1088@1|root,arCOG01371@2157|Archaea,2XUZX@28890|Euryarchaeota,23PA8@183925|Methanobacteria	183925|Methanobacteria	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS2_k127_1563181_2	671143.DAMO_2778	2.844e-12	67.0	COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria	2|Bacteria	M	Nucleotidyl transferase	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS2_k127_1579837_0	98439.AJLL01000008_gene3976	1.169e-10	73.0	COG4886@1|root,COG4886@2|Bacteria,1G0NZ@1117|Cyanobacteria,1JKQE@1189|Stigonemataceae	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1579837_1	1040989.AWZU01000002_gene5236	5.762e-05	51.0	2AEIA@1|root,314DQ@2|Bacteria,1P83F@1224|Proteobacteria,2UYKV@28211|Alphaproteobacteria,3K566@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1579837_2	644284.Arch_0313	0.000807	51.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	ygaU	GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896	-	ko:K21687,ko:K21688,ko:K21691	-	-	-	-	ko00000	-	GH23	-	BON,LysM
LZS2_k127_1583560_1	595593.JREV01000059_gene2422	3.066e-26	115.0	COG0572@1|root,COG0572@2|Bacteria,2HQC8@201174|Actinobacteria	201174|Actinobacteria	F	belongs to the nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Cytidylate_kin
LZS2_k127_1583560_0	118173.KB235914_gene4218	2.833e-39	163.0	COG0457@1|root,COG0457@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_1583560_3	215803.DB30_3743	1.055e-08	57.0	2ANK2@1|root,31DJ5@2|Bacteria,1QAV5@1224|Proteobacteria,435BD@68525|delta/epsilon subdivisions,2WZNS@28221|Deltaproteobacteria,2Z2FM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1583560_2	234267.Acid_4430	4.332e-21	106.0	COG0457@1|root,COG0726@1|root,COG4249@1|root,COG0457@2|Bacteria,COG0726@2|Bacteria,COG4249@2|Bacteria,3Y77C@57723|Acidobacteria	57723|Acidobacteria	G	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Polysacc_deac_1,TPR_2,WD40
LZS2_k127_1584934_0	321332.CYB_1842	2.222e-141	464.0	COG2352@1|root,COG2352@2|Bacteria,1G0VJ@1117|Cyanobacteria,1GYNT@1129|Synechococcus	1117|Cyanobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.ppc	PEPcase
LZS2_k127_1584934_1	1463853.JOHW01000002_gene5679	4.18e-55	218.0	COG0515@1|root,COG0515@2|Bacteria,2IA1X@201174|Actinobacteria	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_158577_1	1416760.AYMS01000133_gene2328	1.539e-23	113.0	COG0457@1|root,COG4585@1|root,COG0457@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,1HX4T@117743|Flavobacteriia,47IXM@76831|Myroides	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,TPR_7,TPR_8
LZS2_k127_158577_0	1541959.KQ51_01518	1.772e-25	111.0	COG0363@1|root,COG0363@2|Bacteria,3WT2H@544448|Tenericutes	2|Bacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
LZS2_k127_1594131_1	1229487.AMYW01000016_gene2479	2.338e-05	55.0	2CI9M@1|root,335Q7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1610438_0	671143.DAMO_1208	5.076e-217	692.0	COG0365@1|root,COG0365@2|Bacteria,2NNSQ@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acs	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS2_k127_1625521_1	671143.DAMO_3054	1.54e-72	253.0	COG5621@1|root,COG5621@2|Bacteria,2NPFN@2323|unclassified Bacteria	2|Bacteria	S	Lipocalin-like domain	attH	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
LZS2_k127_1625521_0	1131269.AQVV01000009_gene1116	8.007e-78	274.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	lolE-2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_164190_0	718252.FP2_18720	2.836e-70	246.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_1642174_0	42565.FP66_00990	5.15e-123	406.0	COG0332@1|root,COG0332@2|Bacteria,1NAGY@1224|Proteobacteria,1RN1T@1236|Gammaproteobacteria,1XNMX@135619|Oceanospirillales	135619|Oceanospirillales	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS2_k127_1642174_1	1188252.AJYK01000092_gene1761	3.04e-79	271.0	COG0819@1|root,COG0819@2|Bacteria,1MVA0@1224|Proteobacteria,1RSHF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Long-chain fatty acid--CoA ligase	-	-	-	-	-	-	-	-	-	-	-	-	Haem_oxygenas_2
LZS2_k127_1642174_2	1216007.AOPM01000100_gene516	7.934e-70	246.0	2CIYT@1|root,2Z7R8@2|Bacteria,1Q6MN@1224|Proteobacteria,1S0UE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_164580_0	572546.Arcpr_1207	2.714e-08	63.0	COG0463@1|root,COG0500@1|root,COG1216@1|root,arCOG01384@2157|Archaea,arCOG04220@2157|Archaea,arCOG04347@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_2,Glycos_transf_2,Methyltransf_11
LZS2_k127_1646826_0	1444309.JAQG01000073_gene301	3.335e-104	367.0	COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,26SSP@186822|Paenibacillaceae	91061|Bacilli	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
LZS2_k127_1651620_0	46234.ANA_C11667	2.336e-27	124.0	COG0793@1|root,COG0793@2|Bacteria,1G031@1117|Cyanobacteria,1HKDU@1161|Nostocales	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	ctpB	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS2_k127_1654907_0	321332.CYB_1758	2.691e-82	289.0	COG0342@1|root,COG0342@2|Bacteria,1G053@1117|Cyanobacteria,1GYPU@1129|Synechococcus	1117|Cyanobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS2_k127_1654907_1	483219.LILAB_26695	2.076e-29	126.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WPGK@28221|Deltaproteobacteria,2YTYN@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
LZS2_k127_1654907_2	1165096.ARWF01000001_gene122	7.623e-24	108.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,2KKCD@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
LZS2_k127_1657828_0	266117.Rxyl_3176	7.459e-79	277.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT,HEAT_2
LZS2_k127_1657828_1	326423.RBAM_034910	2.106e-44	167.0	COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1ZEJ9@1386|Bacillus	91061|Bacilli	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	bacC	-	1.1.1.385	ko:K19548	ko01130,map01130	M00787	R10917	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
LZS2_k127_1666154_1	1138822.PL11_00340	2.988e-12	70.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	pheA	GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,2.3.1.79,4.2.1.51,5.4.99.5	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715,R01728	RC00125,RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_2667	ACT,CM_2,PDT
LZS2_k127_1666154_0	1487953.JMKF01000006_gene5646	2.106e-108	357.0	COG2876@1|root,COG2876@2|Bacteria,1G205@1117|Cyanobacteria,1H90H@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM DAHP synthetase I	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS2_k127_167280_0	483219.LILAB_24970	8.38e-38	150.0	COG1309@1|root,COG1309@2|Bacteria,1N2GG@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS2_k127_167280_1	1144275.COCOR_05485	5.849e-08	64.0	2EICH@1|root,33C3T@2|Bacteria,1P6R7@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3060
LZS2_k127_167813_0	1254432.SCE1572_50130	5.941e-117	388.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,439AV@68525|delta/epsilon subdivisions,2X4IJ@28221|Deltaproteobacteria,2YZ3A@29|Myxococcales	28221|Deltaproteobacteria	F	COG0208 Ribonucleotide reductase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_167813_1	1499967.BAYZ01000028_gene1267	1.796e-29	135.0	COG4249@1|root,COG4249@2|Bacteria,2NRSS@2323|unclassified Bacteria	2|Bacteria	S	Peptidase C13 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,SLH,WD40
LZS2_k127_1686673_1	265729.GS18_0214005	2.451e-30	128.0	2DB83@1|root,2Z7Q0@2|Bacteria,1TQP1@1239|Firmicutes,4HC9T@91061|Bacilli,1ZFUW@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF4127)	M1-530	-	-	-	-	-	-	-	-	-	-	-	DUF4127
LZS2_k127_1686673_0	1211814.CAPG01000047_gene2516	2.513e-115	401.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,1ZBAT@1386|Bacillus	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
LZS2_k127_1688206_2	1403819.BATR01000150_gene5070	1.52e-14	75.0	COG4034@1|root,COG4034@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF1152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1152
LZS2_k127_1688206_1	1173028.ANKO01000139_gene664	3.063e-15	90.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
LZS2_k127_1688206_0	1144275.COCOR_03421	1.557e-90	306.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
LZS2_k127_1694075_1	111781.Lepto7376_1507	1.344e-114	396.0	COG1530@1|root,COG1530@2|Bacteria,1FZX1@1117|Cyanobacteria,1H8P4@1150|Oscillatoriales	1117|Cyanobacteria	J	ribonuclease, Rne Rng family	rne	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
LZS2_k127_1694075_0	936572.HMPREF1148_1040	1.53e-168	565.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1TR2C@1239|Firmicutes,4H33G@909932|Negativicutes	909932|Negativicutes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
LZS2_k127_1694075_2	574087.Acear_0219	5.066e-19	91.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia	186801|Clostridia	S	PHP domain	trpH	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
LZS2_k127_171588_0	485916.Dtox_1254	1.219e-98	325.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,260F1@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
LZS2_k127_171588_3	130081.XP_005702819.1	7.231e-57	211.0	KOG3178@1|root,KOG3178@2759|Eukaryota	2759|Eukaryota	D	O-methyltransferase activity	ASMTL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008172,GO:0008757,GO:0009058,GO:0009059,GO:0009308,GO:0009309,GO:0009987,GO:0010467,GO:0010817,GO:0016740,GO:0016741,GO:0017096,GO:0017144,GO:0018130,GO:0019438,GO:0019538,GO:0030186,GO:0030187,GO:0032259,GO:0034641,GO:0034645,GO:0034754,GO:0042401,GO:0042430,GO:0042435,GO:0042445,GO:0042446,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046483,GO:0046983,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1905939,GO:1905940,GO:2000018,GO:2000019,GO:2000026,GO:2000241,GO:2000242	2.1.1.4	ko:K00543,ko:K13169	ko00380,ko01100,map00380,map01100	M00037	R03130,R04905	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000,ko03041	-	-	-	Dimerisation2,Maf,Methyltransf_2
LZS2_k127_171588_6	1226994.AMZB01000138_gene5663	0.0005687	47.0	COG2804@1|root,COG2804@2|Bacteria,1QW0B@1224|Proteobacteria,1T2PX@1236|Gammaproteobacteria,1YM00@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_171588_4	644968.DFW101_2155	1.024e-21	111.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CS7@68525|delta/epsilon subdivisions,2X7ZW@28221|Deltaproteobacteria,2MHC1@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_7,PAS_9,Response_reg,SBP_bac_3,sCache_3_2
LZS2_k127_171588_1	221288.JH992901_gene1395	1.753e-71	244.0	COG0783@1|root,COG0783@2|Bacteria,1G586@1117|Cyanobacteria,1JI8D@1189|Stigonemataceae	1117|Cyanobacteria	P	Ferritin-like domain	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
LZS2_k127_171588_5	1346330.M472_00450	4.029e-09	64.0	2DXZ5@1|root,34798@2|Bacteria,4P5MB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_171588_2	1380391.JIAS01000019_gene1121	3.25e-62	235.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
LZS2_k127_1732425_0	457415.HMPREF1006_01744	2.614e-05	54.0	COG0668@1|root,COG0668@2|Bacteria,3TBJK@508458|Synergistetes	508458|Synergistetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_1740562_1	118168.MC7420_3740	3.192e-16	93.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G20P@1117|Cyanobacteria	1117|Cyanobacteria	O	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_1740562_2	935557.ATYB01000014_gene3840	0.0004277	49.0	COG0457@1|root,COG0457@2|Bacteria,1NG0U@1224|Proteobacteria,2U0YA@28211|Alphaproteobacteria,4B8S4@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	GlcNAc transferase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_1740562_0	215803.DB30_6675	4.636e-35	153.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4346X@68525|delta/epsilon subdivisions,2XA3R@28221|Deltaproteobacteria,2YXWE@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TonB_C
LZS2_k127_1746816_0	1196029.ALIM01000014_gene3777	2.174e-61	224.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,1ZAYW@1386|Bacillus	91061|Bacilli	V	COG1131 ABC-type multidrug transport system, ATPase component	sagG	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS2_k127_17473_3	911045.PSE_4928	2.16e-16	86.0	COG0372@1|root,COG0789@1|root,COG0372@2|Bacteria,COG0789@2|Bacteria,1MXFW@1224|Proteobacteria,2TTMR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	citrate synthase	MA20_39855	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17,MerR_1
LZS2_k127_17473_0	716544.wcw_0718	1.817e-199	634.0	COG2225@1|root,COG2225@2|Bacteria,2JFT0@204428|Chlamydiae	204428|Chlamydiae	C	Malate synthase	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
LZS2_k127_17473_1	357808.RoseRS_4164	4.325e-198	625.0	COG2224@1|root,COG2224@2|Bacteria,2G61J@200795|Chloroflexi,374VM@32061|Chloroflexia	32061|Chloroflexia	C	PFAM isocitrate lyase and phosphorylmutase	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
LZS2_k127_17473_2	580332.Slit_1271	1.84e-50	198.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
LZS2_k127_1757315_0	588581.Cpap_0708	0.0	1204.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3WGS6@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS2_k127_1757315_1	448385.sce1089	9.467e-61	230.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_1770174_2	1232437.KL661959_gene3110	7.975e-10	70.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
LZS2_k127_1770174_1	459495.SPLC1_S140060	5.979e-44	173.0	COG1091@1|root,COG1091@2|Bacteria,1G3IE@1117|Cyanobacteria,1H8GQ@1150|Oscillatoriales	1117|Cyanobacteria	M	dTDP-4-dehydrorhamnose reductase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS2_k127_1770174_0	266117.Rxyl_1110	9.392e-187	595.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
LZS2_k127_17799_1	247490.KSU1_C1425	1.589e-62	222.0	COG0043@1|root,COG0043@2|Bacteria,2IYCA@203682|Planctomycetes	203682|Planctomycetes	H	COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
LZS2_k127_17799_2	46234.ANA_C20495	1.109e-40	158.0	COG0127@1|root,COG0127@2|Bacteria,1G033@1117|Cyanobacteria,1HJJ7@1161|Nostocales	1117|Cyanobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
LZS2_k127_17799_0	1183438.GKIL_0580	1.5e-217	698.0	COG0317@1|root,COG0317@2|Bacteria,1G0KC@1117|Cyanobacteria	1117|Cyanobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
LZS2_k127_17799_3	517418.Ctha_1393	6.571e-12	74.0	COG0457@1|root,COG0457@2|Bacteria,1FD7Y@1090|Chlorobi	517418.Ctha_1393|-	K	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1783618_2	251221.35214745	5.95e-10	68.0	COG0845@1|root,COG0845@2|Bacteria,1G2V6@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_D23
LZS2_k127_1783618_1	203124.Tery_4782	3.414e-13	80.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H6WA@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_1783618_0	1173028.ANKO01000204_gene4721	1.056e-24	116.0	COG2304@1|root,COG2304@2|Bacteria,1G11R@1117|Cyanobacteria,1H7TP@1150|Oscillatoriales	1117|Cyanobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2,vWA-TerF-like
LZS2_k127_1794524_0	485913.Krac_2961	1.474e-174	588.0	COG1413@1|root,COG1413@2|Bacteria,2G7XV@200795|Chloroflexi	200795|Chloroflexi	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1794524_1	1321786.HMPREF1992_00131	2.614e-78	271.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H1Z4@909932|Negativicutes	909932|Negativicutes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
LZS2_k127_1794524_2	555778.Hneap_1419	2.09e-07	61.0	COG5340@1|root,COG5340@2|Bacteria,1R1GM@1224|Proteobacteria,1S2NC@1236|Gammaproteobacteria,1WZ8H@135613|Chromatiales	135613|Chromatiales	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_180277_0	756272.Plabr_0887	2.279e-29	131.0	COG4782@1|root,COG4782@2|Bacteria,2IWWR@203682|Planctomycetes	203682|Planctomycetes	B	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
LZS2_k127_1803604_2	289376.THEYE_A0559	5.61e-98	329.0	COG0777@1|root,COG0777@2|Bacteria,3J0CK@40117|Nitrospirae	40117|Nitrospirae	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS2_k127_1803604_6	720554.Clocl_2765	6.65e-30	130.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
LZS2_k127_1803604_4	1541065.JRFE01000023_gene3790	8.088e-49	182.0	COG0325@1|root,COG0325@2|Bacteria,1G0GQ@1117|Cyanobacteria,3VHQH@52604|Pleurocapsales	1117|Cyanobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
LZS2_k127_1803604_8	251221.35211265	2.761e-28	121.0	COG1799@1|root,COG1799@2|Bacteria,1G556@1117|Cyanobacteria	1117|Cyanobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
LZS2_k127_1803604_3	1173026.Glo7428_1679	2.509e-50	192.0	COG0739@1|root,COG0739@2|Bacteria,1G076@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
LZS2_k127_1803604_1	562970.Btus_0685	2.528e-116	389.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,2786Z@186823|Alicyclobacillaceae	91061|Bacilli	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
LZS2_k127_1803604_7	1321779.HMPREF1984_02217	6.585e-29	121.0	COG1051@1|root,COG1051@2|Bacteria,37ASE@32066|Fusobacteria	32066|Fusobacteria	F	Hydrolase, NUDIX family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS2_k127_1803604_0	1122216.AUHW01000019_gene58	2.96e-120	396.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4H1YG@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
LZS2_k127_1803604_5	868864.Dester_0631	4.377e-30	125.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G3KI@200783|Aquificae	200783|Aquificae	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
LZS2_k127_1805096_0	1274524.BSONL12_22960	5.101e-13	76.0	2F8ST@1|root,3414Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1805096_1	203124.Tery_1964	2.667e-09	67.0	COG4242@1|root,COG4242@2|Bacteria,1G05A@1117|Cyanobacteria,1H80M@1150|Oscillatoriales	1117|Cyanobacteria	PQ	Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin	cphB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0042802,GO:0042803,GO:0043170,GO:0044238,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	iJN678.slr2001	Peptidase_S51
LZS2_k127_1806366_1	314230.DSM3645_11731	1.621e-68	251.0	COG0421@1|root,COG0421@2|Bacteria,2J51Z@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1806366_0	1118054.CAGW01000101_gene4724	8.616e-194	611.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HV0C@91061|Bacilli,271MY@186822|Paenibacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS2_k127_1809658_0	1121422.AUMW01000019_gene1775	1.157e-155	507.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,2602C@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
LZS2_k127_1816792_2	27923.ML216344a-PA	2.605e-12	78.0	COG3914@1|root,KOG4626@2759|Eukaryota,38EM5@33154|Opisthokonta,3BC3N@33208|Metazoa	33208|Metazoa	GOT	protein N-acetylglucosaminyltransferase activity	OGT	GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_1816792_0	1121335.Clst_1946	4.197e-72	259.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3WGN4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
LZS2_k127_1816792_1	502025.Hoch_4569	5.986e-54	209.0	COG0515@1|root,COG1413@1|root,COG0515@2|Bacteria,COG1413@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_1824916_1	330214.NIDE2363	1.125e-24	111.0	COG0840@1|root,COG1017@1|root,COG2202@1|root,COG0840@2|Bacteria,COG1017@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	bdlA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Globin,MCPsignal,PAS_3,PAS_9
LZS2_k127_1824916_0	1379698.RBG1_1C00001G0780	2.055e-63	232.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
LZS2_k127_1830809_1	304371.MCP_0732	4.144e-24	102.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS2_k127_1830809_0	1142394.PSMK_31170	1.447e-36	145.0	COG3091@1|root,COG3091@2|Bacteria,2J43M@203682|Planctomycetes	203682|Planctomycetes	S	SprT-like family	-	-	-	-	-	-	-	-	-	-	-	-	SprT-like
LZS2_k127_1830809_3	204669.Acid345_1676	8.271e-07	54.0	2FJ4P@1|root,34AUY@2|Bacteria,3Y8PT@57723|Acidobacteria,2JNJ3@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1830809_2	1210884.HG799464_gene10441	7.715e-23	102.0	COG0457@1|root,COG0457@2|Bacteria,2J0VV@203682|Planctomycetes	203682|Planctomycetes	S	Iodothyronine deiodinase	-	-	-	-	-	-	-	-	-	-	-	-	T4_deiodinase
LZS2_k127_1845284_0	671143.DAMO_0415	1.768e-24	104.0	COG0745@1|root,COG0745@2|Bacteria,2NQWD@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_1845948_2	1408254.T458_18130	6.2e-10	64.0	COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,4HEHP@91061|Bacilli,275E1@186822|Paenibacillaceae	91061|Bacilli	I	Serine aminopeptidase, S33	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
LZS2_k127_1845948_0	344747.PM8797T_28784	2.341e-61	228.0	COG4948@1|root,COG4948@2|Bacteria,2IX42@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase muconate lactonizing enzyme	-	-	5.1.1.20,5.5.1.1	ko:K01856,ko:K19802	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229,R10938	RC00903,RC01038,RC01108,RC01321,RC01356,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS2_k127_1845948_1	32057.KB217478_gene1668	7.859e-49	187.0	COG3568@1|root,COG3568@2|Bacteria,1G09C@1117|Cyanobacteria,1HNGQ@1161|Nostocales	1117|Cyanobacteria	S	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
LZS2_k127_1856407_2	69328.PVLB_14510	0.0005195	52.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,Response_reg
LZS2_k127_1856407_1	1217703.F904_02972	1.407e-06	53.0	COG3209@1|root,COG3209@2|Bacteria,1NKW2@1224|Proteobacteria,1SIE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
LZS2_k127_1856407_0	1217703.F904_02974	3.19e-27	120.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,3NJV2@468|Moraxellaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,RHS,RHS_repeat
LZS2_k127_1861816_0	509191.AEDB02000067_gene854	2.772e-22	113.0	COG2766@1|root,COG2766@2|Bacteria,1TRTW@1239|Firmicutes,248GE@186801|Clostridia,3WGH1@541000|Ruminococcaceae	186801|Clostridia	T	PFAM PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
LZS2_k127_1864014_0	292563.Cyast_1827	1.035e-107	364.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1G0IZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
LZS2_k127_1864014_2	638303.Thal_0732	2.744e-24	111.0	COG0517@1|root,COG2199@1|root,COG2203@1|root,COG0517@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,2G47E@200783|Aquificae	200783|Aquificae	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
LZS2_k127_1864014_1	720554.Clocl_2404	3.533e-85	296.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WGMR@541000|Ruminococcaceae	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
LZS2_k127_1864014_3	643867.Ftrac_2907	0.0001766	51.0	COG0758@1|root,COG0758@2|Bacteria,4NF7T@976|Bacteroidetes,47M2T@768503|Cytophagia	976|Bacteroidetes	LU	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
LZS2_k127_1877959_0	246196.MSMEI_0213	2.14e-14	86.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria,232BV@1762|Mycobacteriaceae	201174|Actinobacteria	I	hydrolase	ytpA	GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
LZS2_k127_1885664_1	631362.Thi970DRAFT_03444	9.63e-32	128.0	COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,1T20S@1236|Gammaproteobacteria,1WYSN@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
LZS2_k127_1885664_2	1245469.S58_36300	1.03e-20	97.0	28VS2@1|root,2ZHTX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1885664_0	329726.AM1_3780	5.179e-55	203.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	fhaB2	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	DUF637,Fil_haemagg,Fil_haemagg_2,Haemagg_act,PT-VENN
LZS2_k127_1886377_0	401526.TcarDRAFT_0928	3.763e-201	645.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4H2PQ@909932|Negativicutes	909932|Negativicutes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_1886377_1	204669.Acid345_0062	1.465e-47	189.0	COG0037@1|root,COG0037@2|Bacteria,3Y2F2@57723|Acidobacteria,2JHX8@204432|Acidobacteriia	204432|Acidobacteriia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
LZS2_k127_1891154_0	167555.NATL1_00731	1.941e-18	96.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1GMXH@1117|Cyanobacteria,1MNCP@1212|Prochloraceae	1117|Cyanobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_8
LZS2_k127_1891154_1	411468.CLOSCI_02172	0.0003415	49.0	COG1397@1|root,COG1397@2|Bacteria,1TQXG@1239|Firmicutes,24C2X@186801|Clostridia,21YRK@1506553|Lachnoclostridium	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
LZS2_k127_1894307_1	163908.KB235896_gene4281	4.996e-73	262.0	COG0668@1|root,COG0668@2|Bacteria,1G06A@1117|Cyanobacteria	1117|Cyanobacteria	M	COG0668 Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_1894307_0	338966.Ppro_3258	2.384e-132	447.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,42MXP@68525|delta/epsilon subdivisions,2WMI1@28221|Deltaproteobacteria,43S3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_1894307_2	1279017.AQYJ01000020_gene1310	5.672e-27	117.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1RJPK@1224|Proteobacteria,1T277@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AraC family transcriptional regulator	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
LZS2_k127_1904471_0	383372.Rcas_1005	3.718e-67	239.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,375H1@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
LZS2_k127_1904471_2	10036.XP_005082897.1	0.0004032	51.0	KOG0033@1|root,KOG0033@2759|Eukaryota,38FV7@33154|Opisthokonta,3BF3D@33208|Metazoa,3CSTU@33213|Bilateria,4838S@7711|Chordata,48Z8Q@7742|Vertebrata,3J2JM@40674|Mammalia,35JNC@314146|Euarchontoglires,4PZQU@9989|Rodentia	33208|Metazoa	T	Domain of unknown function (DUF4440)	CAMK2D	GO:0000003,GO:0000082,GO:0000165,GO:0000278,GO:0001558,GO:0001666,GO:0001932,GO:0001934,GO:0002026,GO:0002027,GO:0002028,GO:0002376,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003254,GO:0003298,GO:0003300,GO:0003301,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004683,GO:0005085,GO:0005088,GO:0005488,GO:0005515,GO:0005516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005829,GO:0005886,GO:0005911,GO:0005954,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006928,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0006950,GO:0006952,GO:0006955,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007268,GO:0007275,GO:0007346,GO:0007399,GO:0007507,GO:0007528,GO:0007610,GO:0007611,GO:0007613,GO:0007616,GO:0007617,GO:0007618,GO:0007619,GO:0008015,GO:0008016,GO:0008049,GO:0008092,GO:0008150,GO:0008152,GO:0008200,GO:0008284,GO:0008582,GO:0009628,GO:0009888,GO:0009889,GO:0009893,GO:0009931,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010389,GO:0010468,GO:0010522,GO:0010556,GO:0010562,GO:0010564,GO:0010604,GO:0010611,GO:0010613,GO:0010628,GO:0010646,GO:0010647,GO:0010649,GO:0010660,GO:0010661,GO:0010662,GO:0010663,GO:0010665,GO:0010666,GO:0010766,GO:0010857,GO:0010880,GO:0010881,GO:0010882,GO:0010941,GO:0010942,GO:0010959,GO:0012505,GO:0012506,GO:0014704,GO:0014706,GO:0014742,GO:0014743,GO:0014896,GO:0014897,GO:0014910,GO:0014911,GO:0016020,GO:0016043,GO:0016049,GO:0016247,GO:0016248,GO:0016301,GO:0016310,GO:0016528,GO:0016529,GO:0016740,GO:0016772,GO:0016773,GO:0017016,GO:0017080,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019098,GO:0019219,GO:0019220,GO:0019221,GO:0019222,GO:0019538,GO:0019722,GO:0019725,GO:0019871,GO:0019899,GO:0019932,GO:0019953,GO:0022402,GO:0022414,GO:0022607,GO:0022898,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0030001,GO:0030003,GO:0030004,GO:0030007,GO:0030029,GO:0030048,GO:0030054,GO:0030139,GO:0030154,GO:0030315,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030659,GO:0030666,GO:0031056,GO:0031063,GO:0031090,GO:0031267,GO:0031323,GO:0031325,GO:0031326,GO:0031344,GO:0031399,GO:0031401,GO:0031410,GO:0031432,GO:0031594,GO:0031974,GO:0031981,GO:0031982,GO:0032268,GO:0032270,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032469,GO:0032501,GO:0032502,GO:0032504,GO:0032838,GO:0032879,GO:0032880,GO:0032970,GO:0032991,GO:0033043,GO:0033044,GO:0033267,GO:0034097,GO:0034341,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0035020,GO:0035022,GO:0035051,GO:0035265,GO:0035556,GO:0035637,GO:0036211,GO:0036293,GO:0036477,GO:0040007,GO:0040008,GO:0040012,GO:0040017,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042383,GO:0042391,GO:0042592,GO:0042692,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043194,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043269,GO:0043271,GO:0043408,GO:0043410,GO:0043412,GO:0043502,GO:0043900,GO:0043933,GO:0044057,GO:0044085,GO:0044087,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044291,GO:0044297,GO:0044304,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044843,GO:0045087,GO:0045202,GO:0045211,GO:0045937,GO:0046578,GO:0046579,GO:0046777,GO:0046983,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048584,GO:0048588,GO:0048589,GO:0048609,GO:0048638,GO:0048660,GO:0048661,GO:0048731,GO:0048738,GO:0048786,GO:0048856,GO:0048869,GO:0048878,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050803,GO:0050807,GO:0050808,GO:0050848,GO:0050877,GO:0050890,GO:0050896,GO:0050998,GO:0051020,GO:0051049,GO:0051051,GO:0051056,GO:0051057,GO:0051128,GO:0051146,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051259,GO:0051270,GO:0051272,GO:0051279,GO:0051282,GO:0051336,GO:0051489,GO:0051592,GO:0051704,GO:0051716,GO:0051726,GO:0051924,GO:0051960,GO:0051963,GO:0055001,GO:0055002,GO:0055006,GO:0055007,GO:0055013,GO:0055017,GO:0055065,GO:0055067,GO:0055074,GO:0055075,GO:0055080,GO:0055082,GO:0055117,GO:0055119,GO:0060047,GO:0060048,GO:0060179,GO:0060255,GO:0060278,GO:0060314,GO:0060333,GO:0060341,GO:0060419,GO:0060491,GO:0060537,GO:0061049,GO:0061061,GO:0061337,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070252,GO:0070372,GO:0070374,GO:0070482,GO:0070838,GO:0070887,GO:0071241,GO:0071248,GO:0071277,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072359,GO:0072375,GO:0072503,GO:0072507,GO:0072511,GO:0080090,GO:0086003,GO:0086004,GO:0086091,GO:0090075,GO:0090257,GO:0090311,GO:0097060,GO:0097447,GO:0097458,GO:0097708,GO:0098588,GO:0098590,GO:0098771,GO:0098772,GO:0098793,GO:0098794,GO:0098805,GO:0098900,GO:0098901,GO:0098909,GO:0098916,GO:0099106,GO:0099536,GO:0099537,GO:0099568,GO:0120025,GO:0120032,GO:0120035,GO:0120038,GO:0120111,GO:0140096,GO:1901019,GO:1901077,GO:1901564,GO:1901725,GO:1901844,GO:1901897,GO:1901987,GO:1901990,GO:1902275,GO:1902305,GO:1902306,GO:1902514,GO:1902531,GO:1902533,GO:1902749,GO:1903047,GO:1903076,GO:1903115,GO:1903169,GO:1903506,GO:1903522,GO:1903779,GO:1903827,GO:1904062,GO:1904063,GO:1904115,GO:1904375,GO:1904396,GO:1905475,GO:2000026,GO:2000112,GO:2000145,GO:2000147,GO:2000241,GO:2000649,GO:2000650,GO:2001141,GO:2001257	2.7.11.17	ko:K04515	ko04012,ko04020,ko04024,ko04066,ko04114,ko04217,ko04261,ko04310,ko04360,ko04713,ko04720,ko04722,ko04725,ko04728,ko04740,ko04745,ko04750,ko04911,ko04912,ko04916,ko04921,ko04922,ko04925,ko04934,ko04971,ko05031,ko05152,ko05200,ko05205,ko05214,map04012,map04020,map04024,map04066,map04114,map04217,map04261,map04310,map04360,map04713,map04720,map04722,map04725,map04728,map04740,map04745,map04750,map04911,map04912,map04916,map04921,map04922,map04925,map04934,map04971,map05031,map05152,map05200,map05205,map05214	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	CaMKII_AD,Pkinase
LZS2_k127_1904471_1	224324.aq_854	5.744e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_1917180_0	661478.OP10G_4260	6.728e-53	203.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS2_k127_1917180_1	1499498.EV05_1479	2.42e-10	71.0	COG0204@1|root,COG0204@2|Bacteria,1G1SN@1117|Cyanobacteria,1MKWB@1212|Prochloraceae	1117|Cyanobacteria	I	Alternative locus ID	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS2_k127_1925007_1	880073.Calab_2862	2.23e-67	240.0	COG3437@1|root,COG3437@2|Bacteria,2NP8B@2323|unclassified Bacteria	2|Bacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,PAS_3,Response_reg,dCache_2
LZS2_k127_1925007_0	243231.GSU1723	2.045e-107	369.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,42MXP@68525|delta/epsilon subdivisions,2WMI1@28221|Deltaproteobacteria,43S3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_1925757_2	565655.ECBG_02995	6.719e-43	175.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,4AZWK@81852|Enterococcaceae	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_1925757_0	42256.RradSPS_1100	5.729e-157	508.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,4CPBI@84995|Rubrobacteria	84995|Rubrobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT_4,Malic_M,malic
LZS2_k127_1925757_3	531844.FIC_02146	2.471e-30	123.0	COG0662@1|root,COG0662@2|Bacteria,4NRK3@976|Bacteroidetes,1I3DY@117743|Flavobacteriia	976|Bacteroidetes	G	mannose-6-phosphate isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer
LZS2_k127_1925757_1	1173021.ALWA01000013_gene3018	4.403e-86	291.0	COG1640@1|root,COG1640@2|Bacteria,1G0F2@1117|Cyanobacteria	1117|Cyanobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	iJN678.malQ	Glyco_hydro_77
LZS2_k127_1932144_2	7260.FBpp0243498	3.763e-15	82.0	KOG1037@1|root,KOG1037@2759|Eukaryota,38B7U@33154|Opisthokonta,3BBUM@33208|Metazoa,3CT5Y@33213|Bilateria,41VRJ@6656|Arthropoda,3SG42@50557|Insecta,44XZH@7147|Diptera,45W02@7214|Drosophilidae	33208|Metazoa	KLO	NAD ADP-ribosyltransferase activity. It is involved in the biological process described with protein ADP-ribosylation	PARP1	GO:0000002,GO:0000003,GO:0000122,GO:0000166,GO:0000228,GO:0000302,GO:0000303,GO:0000305,GO:0000715,GO:0000723,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0000791,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001228,GO:0001817,GO:0001818,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002225,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002791,GO:0002792,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003006,GO:0003254,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005703,GO:0005719,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006302,GO:0006310,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006471,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006963,GO:0006974,GO:0006979,GO:0006996,GO:0006997,GO:0007000,GO:0007005,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007552,GO:0007610,GO:0008069,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009303,GO:0009314,GO:0009408,GO:0009410,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009798,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010212,GO:0010243,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010990,GO:0012501,GO:0012505,GO:0014070,GO:0014742,GO:0014743,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016333,GO:0016334,GO:0016485,GO:0016540,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0017144,GO:0018130,GO:0018193,GO:0018209,GO:0018312,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023019,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030225,GO:0030331,GO:0030534,GO:0030575,GO:0030576,GO:0030707,GO:0030808,GO:0030809,GO:0030855,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031960,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032042,GO:0032101,GO:0032103,GO:0032200,GO:0032204,GO:0032205,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032660,GO:0032700,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0033365,GO:0033554,GO:0033683,GO:0033993,GO:0034248,GO:0034250,GO:0034504,GO:0034599,GO:0034605,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0035079,GO:0035080,GO:0035257,GO:0035258,GO:0035363,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042220,GO:0042221,GO:0042391,GO:0042393,GO:0042493,GO:0042592,GO:0042769,GO:0042802,GO:0042826,GO:0042981,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043279,GO:0043388,GO:0043412,GO:0043434,GO:0043484,GO:0043502,GO:0043504,GO:0043523,GO:0043565,GO:0043900,GO:0043902,GO:0043933,GO:0044030,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045087,GO:0045185,GO:0045595,GO:0045597,GO:0045739,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0045980,GO:0046034,GO:0046332,GO:0046483,GO:0047485,GO:0048037,GO:0048148,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050879,GO:0050881,GO:0050882,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051287,GO:0051385,GO:0051427,GO:0051457,GO:0051604,GO:0051606,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051881,GO:0051900,GO:0051901,GO:0055086,GO:0060249,GO:0060255,GO:0060341,GO:0060359,GO:0060390,GO:0060391,GO:0060429,GO:0062012,GO:0062014,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070212,GO:0070412,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0071214,GO:0071241,GO:0071248,GO:0071294,GO:0071310,GO:0071363,GO:0071375,GO:0071417,GO:0071450,GO:0071451,GO:0071478,GO:0071482,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071824,GO:0071840,GO:0072347,GO:0072521,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090092,GO:0090100,GO:0090257,GO:0090304,GO:0090305,GO:0097159,GO:0097305,GO:0097659,GO:0098687,GO:0098781,GO:0104004,GO:0140096,GO:0140097,GO:0140110,GO:1900180,GO:1900182,GO:1900371,GO:1900372,GO:1900407,GO:1900424,GO:1900426,GO:1900542,GO:1900543,GO:1901135,GO:1901214,GO:1901216,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902175,GO:1902531,GO:1902679,GO:1902680,GO:1902882,GO:1903201,GO:1903203,GO:1903376,GO:1903506,GO:1903507,GO:1903508,GO:1903516,GO:1903518,GO:1903530,GO:1903531,GO:1903578,GO:1903579,GO:1903827,GO:1903829,GO:1904044,GO:1904181,GO:1904356,GO:1904357,GO:1904645,GO:1904646,GO:1904760,GO:1904762,GO:1904950,GO:1905076,GO:1905077,GO:1990404,GO:1990837,GO:1990966,GO:2000112,GO:2000113,GO:2000677,GO:2000679,GO:2001020,GO:2001022,GO:2001141,GO:2001169,GO:2001170,GO:2001233,GO:2001242,GO:2001251	2.4.2.30	ko:K10798	ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400	-	-	-	BRCT,PADR1,PARP,PARP_reg,WGR,zf-PARP
LZS2_k127_1932144_0	309799.DICTH_0974	3.576e-45	182.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctpA	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS2_k127_1932144_1	1173264.KI913949_gene594	2.202e-40	160.0	COG1398@1|root,COG1398@2|Bacteria,1G100@1117|Cyanobacteria,1H7HX@1150|Oscillatoriales	1117|Cyanobacteria	I	PFAM Fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS2_k127_1932144_3	314254.OA2633_02206	4.052e-08	54.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,43WSK@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	Belongs to the DNA photolyase family	phrB	GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
LZS2_k127_1932709_0	515635.Dtur_0186	2.285e-144	470.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS2_k127_1932709_1	204669.Acid345_3766	9.957e-102	347.0	COG0312@1|root,COG0312@2|Bacteria,3Y7SM@57723|Acidobacteria	57723|Acidobacteria	L	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
LZS2_k127_1932709_2	1121877.JQKF01000034_gene1984	1.18e-38	156.0	COG4974@1|root,COG4974@2|Bacteria,2IFGC@201174|Actinobacteria	201174|Actinobacteria	L	Phage integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
LZS2_k127_194788_0	1273538.G159_12815	2.967e-43	167.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,26CVX@186818|Planococcaceae	91061|Bacilli	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	yhcZ	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_194788_1	32057.KB217480_gene7997	2.714e-38	151.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HKZW@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	SLH,WG_beta_rep
LZS2_k127_1963759_1	215803.DB30_5360	1.278e-20	101.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1963759_0	1121447.JONL01000002_gene1875	1.235e-28	124.0	2DNU1@1|root,32Z4S@2|Bacteria,1N8FB@1224|Proteobacteria,42VWU@68525|delta/epsilon subdivisions,2WRBE@28221|Deltaproteobacteria,2MCX3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
LZS2_k127_1963759_2	756272.Plabr_0941	2.114e-19	97.0	2DP0I@1|root,3301I@2|Bacteria	2|Bacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
LZS2_k127_1967756_2	1229172.JQFA01000002_gene4768	2.121e-34	145.0	COG4638@1|root,COG4638@2|Bacteria,1G4T7@1117|Cyanobacteria,1HA75@1150|Oscillatoriales	1117|Cyanobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
LZS2_k127_1967756_3	512565.AMIS_57250	1.28e-08	65.0	2CHK1@1|root,2ZBVE@2|Bacteria,2IC9S@201174|Actinobacteria,4DC4I@85008|Micromonosporales	201174|Actinobacteria	S	Red chlorophyll catabolite reductase (RCC reductase)	-	-	-	-	-	-	-	-	-	-	-	-	RCC_reductase
LZS2_k127_1967756_1	926549.KI421517_gene511	2.931e-49	193.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,47N91@768503|Cytophagia	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS2_k127_1967756_0	886293.Sinac_4675	1.354e-155	511.0	COG1449@1|root,COG1449@2|Bacteria,2IYKX@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
LZS2_k127_1973387_1	1121127.JAFA01000003_gene2179	7.906e-65	229.0	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2VMBW@28216|Betaproteobacteria,1K3UB@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Carboxymethylenebutenolidase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH,SnoaL
LZS2_k127_1973387_0	265729.GS18_0218375	4.593e-116	380.0	COG0667@1|root,COG0667@2|Bacteria,1V300@1239|Firmicutes,4HERM@91061|Bacilli	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_1973387_3	1079460.ATTQ01000014_gene2888	0.0002362	49.0	COG2199@1|root,COG4192@1|root,COG5002@1|root,COG3706@2|Bacteria,COG4192@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,2TZD4@28211|Alphaproteobacteria,4BP1D@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,Response_reg
LZS2_k127_1973387_2	443143.GM18_1060	5.754e-50	187.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2WPAC@28221|Deltaproteobacteria,43UU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
LZS2_k127_198265_0	156889.Mmc1_2003	5.019e-113	394.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
LZS2_k127_198265_2	247490.KSU1_B0384	1.067e-22	115.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,SLH,TPR_2,TPR_8
LZS2_k127_198265_1	103690.17130390	3.233e-56	201.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1G59V@1117|Cyanobacteria,1HMS6@1161|Nostocales	1117|Cyanobacteria	K	protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_20,HTH_5
LZS2_k127_1987357_0	1410630.JNKP01000001_gene2339	5.079e-130	454.0	COG0433@1|root,COG0433@2|Bacteria,1TQPR@1239|Firmicutes,249UU@186801|Clostridia,27J8W@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
LZS2_k127_1994630_2	304371.MCP_1487	7.962e-07	60.0	COG0727@1|root,arCOG02579@2157|Archaea	2157|Archaea	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
LZS2_k127_1994630_0	237368.SCABRO_00403	2.052e-87	302.0	COG2377@1|root,COG2377@2|Bacteria,2IZ2P@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
LZS2_k127_1994630_1	1407650.BAUB01000014_gene2211	5.111e-42	158.0	COG0516@1|root,COG0516@2|Bacteria,1G1MX@1117|Cyanobacteria,1GYWK@1129|Synechococcus	1117|Cyanobacteria	C	IMP dehydrogenase GMP reductase	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
LZS2_k127_2015292_0	340099.Teth39_1742	3.814e-97	327.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,42EXJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
LZS2_k127_2015292_1	525904.Tter_0159	3.173e-29	121.0	COG1278@1|root,COG1278@2|Bacteria,2NPTN@2323|unclassified Bacteria	2|Bacteria	K	Probable zinc-ribbon domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD,Ribosomal_S30AE,zf-trcl
LZS2_k127_2015292_2	1120933.ATUY01000003_gene331	1.917e-15	81.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D52E@85005|Actinomycetales	201174|Actinobacteria	T	FHA domain protein	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
LZS2_k127_2017462_0	15368.BRADI4G44760.1	3.419e-07	61.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37QA6@33090|Viridiplantae,3G7J7@35493|Streptophyta,3KRV8@4447|Liliopsida,3I2KC@38820|Poales	35493|Streptophyta	S	Leucine Rich repeat	-	-	-	ko:K10268	-	-	-	-	ko00000,ko04121	-	-	-	LRR_6
LZS2_k127_2024166_0	398512.JQKC01000023_gene3289	5.881e-88	311.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,3WHA0@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
LZS2_k127_2033003_0	671143.DAMO_2518	1.683e-95	327.0	COG3961@1|root,COG3961@2|Bacteria	2|Bacteria	GH	pyruvate decarboxylase activity	ipdC	-	4.1.1.74	ko:K04103	ko00380,ko01100,map00380,map01100	-	R01974	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS2_k127_2039910_0	113355.CM001775_gene3772	3.955e-178	565.0	COG0296@1|root,COG0296@2|Bacteria,1G1IW@1117|Cyanobacteria	1117|Cyanobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	iJN678.glgB	Alpha-amylase,Alpha-amylase_C,CBM_48
LZS2_k127_2048964_0	195250.CM001776_gene1770	9.528e-48	178.0	COG2197@1|root,COG2197@2|Bacteria,1GHXP@1117|Cyanobacteria,1GZT1@1129|Synechococcus	1117|Cyanobacteria	T	Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_2050105_2	234267.Acid_4417	1.721e-11	68.0	COG5586@1|root,COG5586@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2293
LZS2_k127_2050105_0	747365.Thena_0719	3.785e-111	384.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,42EPS@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
LZS2_k127_2050105_1	1173028.ANKO01000204_gene4721	1.396e-28	124.0	COG2304@1|root,COG2304@2|Bacteria,1G11R@1117|Cyanobacteria,1H7TP@1150|Oscillatoriales	1117|Cyanobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2,vWA-TerF-like
LZS2_k127_2052164_0	306281.AJLK01000109_gene3151	2.743e-20	106.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria	1117|Cyanobacteria	U	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
LZS2_k127_2052164_1	1286106.MPL1_12356	1.005e-12	72.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	glnB2	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
LZS2_k127_2052164_2	289376.THEYE_A0922	1.047e-05	54.0	COG0845@1|root,COG0845@2|Bacteria,3J11U@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	-
LZS2_k127_2053360_3	298653.Franean1_5285	7.101e-14	74.0	2FEKQ@1|root,346K4@2|Bacteria,2H96B@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
LZS2_k127_2053360_2	638303.Thal_0732	4.154e-22	104.0	COG0517@1|root,COG2199@1|root,COG2203@1|root,COG0517@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,2G47E@200783|Aquificae	200783|Aquificae	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GGDEF
LZS2_k127_2053360_0	547144.HydHO_0256	5.845e-39	149.0	COG0222@1|root,COG0222@2|Bacteria,2G42K@200783|Aquificae	200783|Aquificae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
LZS2_k127_2053360_1	643648.Slip_2248	6.93e-28	120.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,42K2J@68298|Syntrophomonadaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
LZS2_k127_2061228_2	195250.CM001776_gene510	1.086e-12	70.0	COG0531@1|root,COG0531@2|Bacteria,1G248@1117|Cyanobacteria,1GZZ5@1129|Synechococcus	1117|Cyanobacteria	E	Solute carrier family 12	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
LZS2_k127_2061228_0	43989.cce_0839	7.386e-65	232.0	COG0531@1|root,COG0531@2|Bacteria,1G3K6@1117|Cyanobacteria,3KJMN@43988|Cyanothece	1117|Cyanobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
LZS2_k127_2061228_1	43989.cce_0839	5.255e-34	136.0	COG0531@1|root,COG0531@2|Bacteria,1G3K6@1117|Cyanobacteria,3KJMN@43988|Cyanothece	1117|Cyanobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
LZS2_k127_2078742_3	1340493.JNIF01000003_gene1561	4.346e-05	52.0	COG2802@1|root,COG2802@2|Bacteria,3Y7JR@57723|Acidobacteria	57723|Acidobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
LZS2_k127_2078742_1	1396858.Q666_00795	7.451e-100	335.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,1RM88@1236|Gammaproteobacteria,465C3@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS2_k127_2078742_0	240016.ABIZ01000001_gene677	1.501e-129	426.0	COG2907@1|root,COG2907@2|Bacteria,46SMG@74201|Verrucomicrobia,2IVF5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS2_k127_2078742_2	1123355.JHYO01000044_gene1212	3.161e-48	183.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2TUX0@28211|Alphaproteobacteria,36Y8J@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
LZS2_k127_2103340_0	1499967.BAYZ01000100_gene3469	3.088e-54	201.0	COG4034@1|root,COG4034@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF1152)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1152
LZS2_k127_2115076_2	304371.MCP_0628	3.051e-50	182.0	COG1196@1|root,arCOG00371@2157|Archaea,2XSVK@28890|Euryarchaeota,2N92I@224756|Methanomicrobia	224756|Methanomicrobia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
LZS2_k127_2115076_4	1261545.MBE-HAL_0486	5.72e-26	119.0	COG1354@1|root,arCOG02610@2157|Archaea,2XT0N@28890|Euryarchaeota,23TJC@183963|Halobacteria	183963|Halobacteria	L	chromosome segregation and condensation protein ScpA	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
LZS2_k127_2115076_5	565033.GACE_1479	4.883e-25	115.0	COG1386@1|root,arCOG02613@2157|Archaea,2XZ7Q@28890|Euryarchaeota,2468R@183980|Archaeoglobi	183980|Archaeoglobi	K	segregation and condensation protein B	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
LZS2_k127_2115076_3	986075.CathTA2_0503	3.312e-36	147.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli	91061|Bacilli	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
LZS2_k127_2115076_6	999411.HMPREF1092_01190	1.982e-12	75.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,36I3V@31979|Clostridiaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
LZS2_k127_2115076_0	485916.Dtox_3113	2.903e-71	253.0	COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,24AM7@186801|Clostridia,26048@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM tRNA 2-selenouridine synthase	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
LZS2_k127_2115076_1	1121422.AUMW01000003_gene927	5.22e-53	196.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,2601W@186807|Peptococcaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
LZS2_k127_2133633_2	1267533.KB906742_gene773	1.407e-06	53.0	2DBBT@1|root,2Z8AC@2|Bacteria	2|Bacteria	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
LZS2_k127_2133633_1	316274.Haur_2274	6.667e-79	269.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi,3773X@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_2133633_0	671143.DAMO_0414	1.389e-80	280.0	COG0642@1|root,COG2205@2|Bacteria,2NNNV@2323|unclassified Bacteria	2|Bacteria	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
LZS2_k127_2148498_0	864702.OsccyDRAFT_2609	8.701e-16	85.0	COG0457@1|root,COG0457@2|Bacteria,1G0N0@1117|Cyanobacteria,1HEV3@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_2148498_1	1144275.COCOR_01518	5.917e-06	57.0	COG4932@1|root,COG4932@2|Bacteria,1R5S8@1224|Proteobacteria	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS2_k127_2153393_1	1120951.AUBG01000005_gene2137	3.737e-05	50.0	COG5592@1|root,COG5592@2|Bacteria,4NP8M@976|Bacteroidetes,1I24Y@117743|Flavobacteriia	976|Bacteroidetes	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
LZS2_k127_218183_1	211165.AJLN01000083_gene1477	2.851e-98	331.0	COG4100@1|root,COG4100@2|Bacteria,1G03T@1117|Cyanobacteria,1JH10@1189|Stigonemataceae	1117|Cyanobacteria	P	Methionine gamma-lyase	metC	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Met_gamma_lyase
LZS2_k127_218183_0	197221.22295271	5.627e-126	410.0	COG0462@1|root,COG0462@2|Bacteria,1G00F@1117|Cyanobacteria	1117|Cyanobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
LZS2_k127_218183_2	330214.NIDE3370	7.45e-66	230.0	COG0491@1|root,COG0491@2|Bacteria,3J0VN@40117|Nitrospirae	40117|Nitrospirae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_218183_3	751945.Theos_1970	0.0001379	54.0	COG2804@1|root,COG2804@2|Bacteria,1WIW9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilF	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
LZS2_k127_2181884_1	521674.Plim_0871	3.647e-10	70.0	COG2267@1|root,COG2267@2|Bacteria,2J04Z@203682|Planctomycetes	203682|Planctomycetes	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_2181884_0	358823.DF19_21855	5.216e-14	82.0	COG0508@1|root,COG0508@2|Bacteria,2HEGK@201174|Actinobacteria	201174|Actinobacteria	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
LZS2_k127_2195805_0	1170562.Cal6303_2503	6.795e-07	61.0	COG3021@1|root,COG3021@2|Bacteria,1G1V5@1117|Cyanobacteria	1117|Cyanobacteria	S	endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS2_k127_2198722_0	382464.ABSI01000005_gene1362	8.51e-115	377.0	COG0320@1|root,COG0320@2|Bacteria,46TZG@74201|Verrucomicrobia,2ITX7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
LZS2_k127_2198722_1	1121405.dsmv_1098	3.873e-41	156.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2MN0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
LZS2_k127_2201306_0	1209989.TepiRe1_2363	8.03e-58	222.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,42F6G@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
LZS2_k127_2201306_1	255470.cbdbA1372	3.593e-38	156.0	COG0484@1|root,COG0484@2|Bacteria,2G657@200795|Chloroflexi,34CZG@301297|Dehalococcoidia	301297|Dehalococcoidia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
LZS2_k127_2201306_2	931627.MycrhDRAFT_5768	1.265e-09	70.0	COG0639@1|root,COG0639@2|Bacteria,2GMS4@201174|Actinobacteria	201174|Actinobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
LZS2_k127_2210128_2	344747.PM8797T_15291	5.067e-36	150.0	COG3631@1|root,COG3631@2|Bacteria,2J52S@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
LZS2_k127_2210128_1	706587.Desti_2494	4.818e-41	168.0	COG5183@1|root,COG5183@2|Bacteria	2|Bacteria	A	chlorophyll binding	-	-	-	ko:K12092	ko05120,map05120	M00564	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7.12.1	-	-	CagY_I,CagY_M,TrbI
LZS2_k127_2210128_0	1123261.AXDW01000024_gene2057	7.616e-98	331.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,1X4D8@135614|Xanthomonadales	135614|Xanthomonadales	S	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
LZS2_k127_2211497_1	1278073.MYSTI_06164	3.082e-16	83.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,42MRF@68525|delta/epsilon subdivisions,2WNGJ@28221|Deltaproteobacteria,2YW7Q@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
LZS2_k127_2211497_0	748449.Halha_2472	5.674e-50	182.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3WCAY@53433|Halanaerobiales	186801|Clostridia	G	sugar-phosphate isomerases, RpiB LacA LacB family	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
LZS2_k127_2211497_2	645991.Sgly_0900	8.491e-11	72.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,262K6@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
LZS2_k127_2213549_1	1450525.JATV01000018_gene2454	0.0006697	45.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia,2NU4E@237|Flavobacterium	976|Bacteroidetes	T	BatE protein	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
LZS2_k127_2213549_0	118168.MC7420_5756	7.468e-91	311.0	COG2084@1|root,COG2084@2|Bacteria,1G1GH@1117|Cyanobacteria,1H8UU@1150|Oscillatoriales	1117|Cyanobacteria	I	NAD binding domain of 6-phosphogluconate dehydrogenase	mmsB	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
LZS2_k127_2223216_1	1210884.HG799471_gene14691	5.088e-15	79.0	2EFSK@1|root,339IK@2|Bacteria,2J2MT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2223216_0	13035.Dacsa_2698	6.848e-27	127.0	COG0793@1|root,COG0793@2|Bacteria,1G031@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	ctpB	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS2_k127_2227391_13	1280674.AUJK01000019_gene184	1.418e-05	55.0	COG0457@1|root,COG3577@1|root,COG0457@2|Bacteria,COG3577@2|Bacteria,4NGN5@976|Bacteroidetes,2FR9N@200643|Bacteroidia	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_17,TPR_2,TPR_8,gag-asp_proteas
LZS2_k127_2227391_0	1123508.JH636444_gene5476	1.135e-149	495.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
LZS2_k127_2227391_3	1122223.KB890702_gene1361	5.584e-42	174.0	COG0160@1|root,COG0160@2|Bacteria,1WITZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_2227391_5	858215.Thexy_2002	2.646e-33	137.0	COG1392@1|root,COG1392@2|Bacteria,1UYRI@1239|Firmicutes,25J7X@186801|Clostridia,42G2H@68295|Thermoanaerobacterales	186801|Clostridia	P	Phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
LZS2_k127_2227391_1	1121035.AUCH01000005_gene113	7.02e-72	254.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,2KUZI@206389|Rhodocyclales	206389|Rhodocyclales	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS2_k127_2227391_2	1123252.ATZF01000013_gene2860	8.199e-46	187.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27B9F@186824|Thermoactinomycetaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_2227391_11	498761.HM1_3150	2.194e-09	60.0	2E4EA@1|root,32Z9I@2|Bacteria,1VG12@1239|Firmicutes,24R4R@186801|Clostridia	186801|Clostridia	S	ORF located using Blastx	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2227391_4	1150469.RSPPHO_03247	3.387e-34	134.0	2DMNG@1|root,32SP1@2|Bacteria,1NAN7@1224|Proteobacteria,2UD5X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2227391_9	498761.HM1_3149	2.199e-12	67.0	2DMNG@1|root,32SP1@2|Bacteria,1VAXC@1239|Firmicutes,24P9Q@186801|Clostridia	186801|Clostridia	S	COG NOG14552 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2227391_8	1173021.ALWA01000027_gene2631	2.084e-12	67.0	2EK6X@1|root,33DXA@2|Bacteria,1GFHH@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2227391_6	3712.Bo3g127600.1	8.631e-27	111.0	2E4EA@1|root,2S5QZ@2759|Eukaryota,38A44@33090|Viridiplantae,3GWQ7@35493|Streptophyta,3I1HA@3699|Brassicales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2227391_10	1403946.Q615_SPAC00010G0001	1.006e-10	62.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,4HYZ4@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2227391_7	1382230.ASAP_2763	3.309e-23	100.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2227929_0	1121087.AUCK01000005_gene701	7.673e-142	477.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS2_k127_2227929_1	395961.Cyan7425_3912	2.791e-51	184.0	COG0105@1|root,COG0105@2|Bacteria,1G4ZN@1117|Cyanobacteria,3KHQN@43988|Cyanothece	1117|Cyanobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
LZS2_k127_2234215_0	251221.35210581	6.807e-176	570.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_2234215_1	251221.35210580	1.815e-130	434.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cvaA	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,OEP
LZS2_k127_2234215_2	1249975.JQLP01000001_gene3420	2.383e-21	106.0	COG1538@1|root,COG1538@2|Bacteria,4NEH3@976|Bacteroidetes,1HXJ9@117743|Flavobacteriia,2P79Y@244698|Gillisia	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS2_k127_2241609_1	649747.HMPREF0083_06088	1.009e-40	164.0	COG0860@1|root,COG0860@2|Bacteria,1V5SF@1239|Firmicutes,4HJNA@91061|Bacilli,26RP7@186822|Paenibacillaceae	91061|Bacilli	M	N-acetylmuramoyl-L-alanine amidase	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
LZS2_k127_2241609_0	1499498.EV05_1524	8.42e-47	180.0	COG0796@1|root,COG0796@2|Bacteria,1G0W6@1117|Cyanobacteria,1MM9Q@1212|Prochloraceae	1117|Cyanobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
LZS2_k127_2258533_1	395961.Cyan7425_4251	2.974e-102	342.0	2DBBI@1|root,2Z888@2|Bacteria,1GR4N@1117|Cyanobacteria	1117|Cyanobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	YHYH
LZS2_k127_2258533_0	331869.BAL199_02649	8.425e-229	720.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2TT46@28211|Alphaproteobacteria,4BPXK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
LZS2_k127_2258533_2	471855.Shel_05910	2.978e-05	52.0	COG5330@1|root,COG5330@2|Bacteria,2HBF0@201174|Actinobacteria	201174|Actinobacteria	S	Leucine rich repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_225862_0	755178.Cyan10605_1674	2.23e-49	194.0	COG1316@1|root,COG1316@2|Bacteria,1G12M@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Cell envelope-related transcriptional attenuator	psr	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
LZS2_k127_225862_1	883078.HMPREF9695_03833	5.233e-43	163.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,3JTI5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	cation efflux	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
LZS2_k127_2263696_0	748449.Halha_0257	6.309e-147	479.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WADV@53433|Halanaerobiales	186801|Clostridia	G	PFAM Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
LZS2_k127_2263696_1	1095769.CAHF01000013_gene3248	2.275e-09	67.0	COG1994@1|root,COG1994@2|Bacteria,1PM1Q@1224|Proteobacteria,2VM3E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2264257_2	1127673.GLIP_1719	3.237e-23	107.0	COG0317@1|root,COG0317@2|Bacteria,1RIM6@1224|Proteobacteria,1T0UX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
LZS2_k127_2264257_1	1278073.MYSTI_08028	3.486e-36	153.0	COG0745@1|root,COG2199@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2X7CV@28221|Deltaproteobacteria,2YUZ7@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
LZS2_k127_2264257_0	1123321.KB905819_gene5777	7.945e-44	183.0	COG0515@1|root,COG0515@2|Bacteria,2GM1F@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_226696_4	1183438.GKIL_2257	0.000151	53.0	COG0589@1|root,COG0589@2|Bacteria,1G6JK@1117|Cyanobacteria	1117|Cyanobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_226696_3	483219.LILAB_34350	2.585e-07	61.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_226696_2	925775.XVE_3335	5.044e-12	69.0	COG2155@1|root,COG2155@2|Bacteria,1N77I@1224|Proteobacteria,1SHMF@1236|Gammaproteobacteria,1XB8D@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
LZS2_k127_226696_0	292564.Cyagr_2454	5.803e-101	344.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,22S6X@167375|Cyanobium	1117|Cyanobacteria	E	amino acid	-	-	-	ko:K03294,ko:K13868	ko04974,map04974	-	-	-	ko00000,ko00001,ko02000	2.A.3.2,2.A.3.8.15	-	-	AA_permease_2
LZS2_k127_226696_1	698961.CGSMWGv6119V5_03156	5.425e-44	175.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CZFU@85004|Bifidobacteriales	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_2273106_1	926566.Terro_2818	1.245e-07	66.0	COG0457@1|root,COG0457@2|Bacteria,3Y6J0@57723|Acidobacteria,2JKHK@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_2273106_0	204669.Acid345_0379	6.946e-146	478.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,3Y3MS@57723|Acidobacteria,2JMPY@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.1.1.1,1.2.1.10,1.2.1.81	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
LZS2_k127_2283182_1	518766.Rmar_1680	2.953e-30	123.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1FIWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	HP	ThiF family	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
LZS2_k127_2283182_0	351160.RRC116	5.093e-148	481.0	COG0318@1|root,arCOG00856@2157|Archaea,2XSZG@28890|Euryarchaeota,2N90V@224756|Methanomicrobia	224756|Methanomicrobia	I	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS2_k127_2284003_0	373994.Riv7116_1940	1.543e-82	288.0	COG0793@1|root,COG0793@2|Bacteria,1G1YJ@1117|Cyanobacteria,1HKZG@1161|Nostocales	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
LZS2_k127_2284003_1	1148.1653502	1.876e-05	55.0	COG0457@1|root,COG0457@2|Bacteria	1148.1653502|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2290446_2	765420.OSCT_3196	3.496e-18	89.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_2290446_1	1384066.JAGT01000001_gene2356	1.427e-44	184.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3WGK8@541000|Ruminococcaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_2290446_0	290397.Adeh_3744	1.266e-56	201.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2YXUH@29|Myxococcales	28221|Deltaproteobacteria	Q	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS2_k127_2290446_3	1297865.APJD01000015_gene3434	4.766e-18	96.0	2EBAQ@1|root,30TPG@2|Bacteria,1MXDU@1224|Proteobacteria,2U4SN@28211|Alphaproteobacteria,3JWVI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
LZS2_k127_2290446_4	99598.Cal7507_2817	2.358e-05	49.0	2DSKE@1|root,33GH9@2|Bacteria,1GGDG@1117|Cyanobacteria,1HSHM@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2298962_0	313603.FB2170_04070	6.682e-41	165.0	2ENMR@1|root,33G92@2|Bacteria,4P0KF@976|Bacteroidetes,1I7HJ@117743|Flavobacteriia	976|Bacteroidetes	S	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS2_k127_2300682_0	1128427.KB904821_gene1154	2.469e-162	528.0	COG0111@1|root,COG0111@2|Bacteria,1FZZU@1117|Cyanobacteria,1HHVM@1150|Oscillatoriales	1117|Cyanobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.serA	2-Hacid_dh,2-Hacid_dh_C,ACT
LZS2_k127_2301150_1	1049564.TevJSym_at00210	4.017e-110	366.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1J58Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS2_k127_2301150_0	1528106.JRJE01000027_gene452	3.644e-114	381.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria,2JPZ6@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family 2	-	-	2.4.1.83,2.4.2.53	ko:K00721,ko:K10012	ko00510,ko00520,ko01100,ko01503,map00510,map00520,map01100,map01503	M00721,M00761	R01009,R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
LZS2_k127_2301150_2	671143.DAMO_2261	5.106e-35	143.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_2313471_3	886293.Sinac_6015	1.815e-56	205.0	COG1309@1|root,COG1309@2|Bacteria,2J0CY@203682|Planctomycetes	203682|Planctomycetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS2_k127_2313471_2	118161.KB235922_gene4347	4.483e-58	220.0	COG0845@1|root,COG0845@2|Bacteria,1G0EP@1117|Cyanobacteria,3VKZI@52604|Pleurocapsales	1117|Cyanobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
LZS2_k127_2313471_0	251221.35213062	0.0	1244.0	COG0841@1|root,COG0841@2|Bacteria,1G0C2@1117|Cyanobacteria	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS2_k127_2313471_1	450851.PHZ_c0602	1.353e-113	382.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2TR3D@28211|Alphaproteobacteria,2KFZ2@204458|Caulobacterales	204458|Caulobacterales	E	Serine dehydratase	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
LZS2_k127_2319642_2	102129.Lepto7375DRAFT_8100	7.365e-17	81.0	COG0421@1|root,COG1586@1|root,COG0421@2|Bacteria,COG1586@2|Bacteria,1G36Y@1117|Cyanobacteria,1HH8X@1150|Oscillatoriales	1117|Cyanobacteria	E	Spermidine synthase tetramerisation domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
LZS2_k127_2319642_1	696747.NIES39_D05890	1.097e-26	121.0	COG1073@1|root,COG1073@2|Bacteria,1G2EP@1117|Cyanobacteria,1H83Z@1150|Oscillatoriales	1117|Cyanobacteria	S	of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
LZS2_k127_2319642_0	635013.TherJR_1046	9.694e-80	299.0	COG2199@1|root,COG2203@1|root,COG3287@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3287@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,260BC@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,DUF3369,GGDEF,HD,HD_5,Response_reg
LZS2_k127_2320283_0	1131269.AQVV01000065_gene1812	1.068e-49	183.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	ssuE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006790,GO:0006805,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008752,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009111,GO:0009267,GO:0009308,GO:0009310,GO:0009410,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0010181,GO:0016043,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019439,GO:0019694,GO:0019752,GO:0022607,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032787,GO:0033554,GO:0034641,GO:0036094,GO:0042178,GO:0042221,GO:0042365,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0042594,GO:0043167,GO:0043168,GO:0043420,GO:0043421,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046306,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0052873,GO:0055114,GO:0065003,GO:0070887,GO:0071466,GO:0071496,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.5.1.38,1.5.1.45	ko:K00299,ko:K16902	ko00380,ko00740,ko00920,ko01100,map00380,map00740,map00920,map01100	-	R05706,R07210,R09517,R09520,R09748,R10206	RC00046,RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	iAF1260.b0937,iB21_1397.B21_00948,iBWG_1329.BWG_0789,iE2348C_1286.E2348C_0930,iECBD_1354.ECBD_2658,iECB_1328.ECB_00941,iECDH10B_1368.ECDH10B_1007,iECDH1ME8569_1439.ECDH1ME8569_0888,iECD_1391.ECD_00941,iECIAI1_1343.ECIAI1_0978,iECO103_1326.ECO103_0982,iECW_1372.ECW_m1047,iEKO11_1354.EKO11_2893,iETEC_1333.ETEC_1005,iEcDH1_1363.EcDH1_2706,iEcE24377_1341.EcE24377A_1052,iEcHS_1320.EcHS_A1046,iEcolC_1368.EcolC_2659,iJO1366.b0937,iSB619.SA_RS01880,iSbBS512_1146.SbBS512_E2381,iUMNK88_1353.UMNK88_1092,iWFL_1372.ECW_m1047,iY75_1357.Y75_RS04870	FMN_red
LZS2_k127_2332341_0	525904.Tter_1685	1.998e-61	222.0	COG0648@1|root,COG0648@2|Bacteria,2NNN3@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
LZS2_k127_2332341_1	251221.35211375	1.206e-10	70.0	COG2197@1|root,COG2197@2|Bacteria,1G1P0@1117|Cyanobacteria	1117|Cyanobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_2341841_0	6500.XP_005097652.1	1.093e-77	273.0	COG1960@1|root,KOG0140@2759|Eukaryota,38BNR@33154|Opisthokonta,3BCJM@33208|Metazoa,3CV7W@33213|Bilateria	33208|Metazoa	I	medium-chain-acyl-CoA dehydrogenase activity	ACADM	GO:0000062,GO:0000166,GO:0000271,GO:0001889,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006082,GO:0006091,GO:0006109,GO:0006111,GO:0006112,GO:0006575,GO:0006577,GO:0006578,GO:0006629,GO:0006631,GO:0006635,GO:0006807,GO:0006950,GO:0007275,GO:0007507,GO:0007584,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009062,GO:0009250,GO:0009266,GO:0009409,GO:0009437,GO:0009605,GO:0009628,GO:0009719,GO:0009725,GO:0009791,GO:0009888,GO:0009889,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010675,GO:0010906,GO:0014070,GO:0014706,GO:0015980,GO:0016020,GO:0016042,GO:0016043,GO:0016051,GO:0016054,GO:0016491,GO:0016604,GO:0016607,GO:0016627,GO:0016853,GO:0017076,GO:0019216,GO:0019222,GO:0019254,GO:0019395,GO:0019752,GO:0022607,GO:0030154,GO:0030258,GO:0030424,GO:0030554,GO:0031090,GO:0031323,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033692,GO:0033993,GO:0034440,GO:0034637,GO:0034641,GO:0034645,GO:0035051,GO:0036094,GO:0042221,GO:0042398,GO:0042493,GO:0042594,GO:0042692,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043436,GO:0043933,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045329,GO:0046395,GO:0046688,GO:0048037,GO:0048513,GO:0048545,GO:0048731,GO:0048732,GO:0048738,GO:0048856,GO:0048869,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0051791,GO:0051793,GO:0055007,GO:0055114,GO:0060537,GO:0061008,GO:0061061,GO:0062012,GO:0065003,GO:0065007,GO:0070013,GO:0070991,GO:0071704,GO:0071840,GO:0072329,GO:0072359,GO:0080090,GO:0097159,GO:0097164,GO:0097367,GO:0097458,GO:0120025,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901567,GO:1901575,GO:1901576,GO:1901681	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_23426_0	82654.Pse7367_2304	4.035e-68	243.0	COG0616@1|root,COG0616@2|Bacteria,1G1AY@1117|Cyanobacteria,1H7U5@1150|Oscillatoriales	1117|Cyanobacteria	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS2_k127_23426_1	1121335.Clst_0843	3.078e-11	64.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
LZS2_k127_2364842_2	1121447.JONL01000001_gene330	4.407e-78	267.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2M9IV@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS2_k127_2364842_1	1121472.AQWN01000005_gene2567	2.892e-85	292.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,2607M@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS2_k127_2364842_0	269799.Gmet_0366	2.576e-114	378.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,43U97@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
LZS2_k127_236495_1	1536774.H70357_12690	1.693e-41	161.0	COG2345@1|root,COG2345@2|Bacteria,1V3GF@1239|Firmicutes,4HG9G@91061|Bacilli,275GJ@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20
LZS2_k127_236495_0	926561.KB900620_gene2963	4.427e-131	434.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3WABC@53433|Halanaerobiales	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
LZS2_k127_236495_2	316274.Haur_4461	1.926e-23	104.0	COG1543@1|root,COG1543@2|Bacteria,2GBQW@200795|Chloroflexi,3764R@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
LZS2_k127_2371910_1	1121428.DESHY_160033___1	2.187e-70	250.0	COG0530@1|root,COG0530@2|Bacteria,1UQT7@1239|Firmicutes,258JC@186801|Clostridia,260UA@186807|Peptococcaceae	186801|Clostridia	P	PFAM sodium calcium exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS2_k127_2371910_2	1379698.RBG1_1C00001G0539	1.83e-22	100.0	COG0721@1|root,COG0721@2|Bacteria,2NPXC@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
LZS2_k127_2371910_0	1121430.JMLG01000002_gene1257	7.114e-219	691.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,260W1@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
LZS2_k127_2376448_1	251229.Chro_1416	4.876e-54	197.0	COG3340@1|root,COG3340@2|Bacteria,1G6TI@1117|Cyanobacteria,3VMJQ@52604|Pleurocapsales	1117|Cyanobacteria	E	Peptidase family S51	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S51
LZS2_k127_2376448_2	484770.UFO1_3317	3.62e-41	160.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4H1XZ@909932|Negativicutes	909932|Negativicutes	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
LZS2_k127_2376448_4	91464.S7335_5592	9.741e-29	128.0	COG1388@1|root,COG1388@2|Bacteria,1G77T@1117|Cyanobacteria	1117|Cyanobacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2376448_6	702113.PP1Y_Mpl11547	5.131e-21	94.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2TUNY@28211|Alphaproteobacteria,2K3US@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
LZS2_k127_2376448_7	1532558.JL39_14280	2.364e-13	70.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2TUNY@28211|Alphaproteobacteria,4B8JU@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	DDE domain	-	-	-	ko:K18320	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
LZS2_k127_2376448_5	435591.BDI_2630	9.748e-24	109.0	COG4639@1|root,COG4639@2|Bacteria,4P3R5@976|Bacteroidetes	976|Bacteroidetes	S	Zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2376448_0	59196.RICGR_0276	2.621e-76	266.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1SNDH@1236|Gammaproteobacteria,1JGK4@118969|Legionellales	118969|Legionellales	H	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
LZS2_k127_2376448_3	648757.Rvan_2969	4.955e-35	140.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,2UAQT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
LZS2_k127_2392375_0	1261545.MBE-HAL_0270	2.094e-50	192.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria	183963|Halobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2,Usp
LZS2_k127_2396584_0	330214.NIDE3406	5.605e-216	683.0	COG0129@1|root,COG0129@2|Bacteria,3J0ES@40117|Nitrospirae	40117|Nitrospirae	EG	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
LZS2_k127_2396584_1	1089439.KB902261_gene326	8.305e-162	523.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,460KU@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
LZS2_k127_2397772_2	1123058.KB894220_gene2177	6.379e-06	50.0	COG1846@1|root,COG1846@2|Bacteria,4NSNN@976|Bacteroidetes,1I4EX@117743|Flavobacteriia	976|Bacteroidetes	K	helix_turn_helix multiple antibiotic resistance protein	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
LZS2_k127_2397772_1	886293.Sinac_7442	1.473e-07	64.0	COG0666@1|root,COG0666@2|Bacteria,2J2XP@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
LZS2_k127_2397772_0	208439.AJAP_08265	2.349e-34	150.0	COG0666@1|root,COG0666@2|Bacteria,2I0BM@201174|Actinobacteria,4E0VB@85010|Pseudonocardiales	201174|Actinobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4
LZS2_k127_240350_1	1123070.KB899249_gene323	7.34e-35	139.0	COG0560@1|root,COG0560@2|Bacteria,46UCT@74201|Verrucomicrobia,2ITII@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
LZS2_k127_240350_0	1128398.Curi_c08230	1.914e-54	209.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,267KT@186813|unclassified Clostridiales	186801|Clostridia	H	Mur ligase middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS2_k127_240459_1	661478.OP10G_0723	1.517e-70	251.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	dpaL	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.6,3.5.1.87,4.3.1.15,4.3.1.17,4.3.1.19	ko:K01751,ko:K01754,ko:K06016,ko:K17989	ko00240,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00240,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00046,M00570	R00220,R00590,R00905,R00996,R04666	RC00096,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_240459_2	436114.SYO3AOP1_0844	3.078e-38	149.0	COG1586@1|root,COG1586@2|Bacteria	2|Bacteria	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	-	2.5.1.16,4.1.1.50	ko:K00797,ko:K01611	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R00178,R01920,R02869,R08359	RC00021,RC00053,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synth
LZS2_k127_240459_0	1158318.ATXC01000002_gene1498	2.207e-289	927.0	COG0587@1|root,COG0587@2|Bacteria,2G3PZ@200783|Aquificae	200783|Aquificae	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
LZS2_k127_240529_1	479432.Sros_0533	6.632e-17	84.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,4EHTN@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
LZS2_k127_240529_2	269799.Gmet_1404	8.686e-15	89.0	COG3014@1|root,COG3014@2|Bacteria,1RAHY@1224|Proteobacteria,43CAG@68525|delta/epsilon subdivisions,2X7KZ@28221|Deltaproteobacteria,43SFY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_240529_0	1239962.C943_00944	4.652e-29	119.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_2408367_0	1349822.NSB1T_14405	1.371e-33	139.0	COG0737@1|root,COG0737@2|Bacteria,4NESM@976|Bacteroidetes,2FM91@200643|Bacteroidia,231HV@171551|Porphyromonadaceae	976|Bacteroidetes	F	Calcineurin-like phosphoesterase	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
LZS2_k127_2414454_0	1321778.HMPREF1982_00753	1.791e-126	420.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,268IV@186813|unclassified Clostridiales	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS2_k127_2414454_1	329726.AM1_0571	6.133e-09	63.0	COG0346@1|root,COG0346@2|Bacteria,1G71D@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS2_k127_2446221_0	517418.Ctha_0233	1.286e-106	364.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1FDRS@1090|Chlorobi	1090|Chlorobi	C	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
LZS2_k127_2446221_1	309799.DICTH_0359	2.945e-88	308.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	bglB	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
LZS2_k127_2447600_1	525897.Dbac_1496	1.095e-30	126.0	COG3968@1|root,COG3968@2|Bacteria,1QUKF@1224|Proteobacteria,42PBH@68525|delta/epsilon subdivisions,2WJZG@28221|Deltaproteobacteria,2M9AA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Glutamine synthetase, catalytic region	glnN	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
LZS2_k127_2447600_0	1191523.MROS_1971	1.423e-64	224.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS2_k127_2447600_2	1207063.P24_18611	7.826e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,1PEX8@1224|Proteobacteria,2VCCI@28211|Alphaproteobacteria,2JYET@204441|Rhodospirillales	204441|Rhodospirillales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
LZS2_k127_2466088_0	221288.JH992901_gene3690	1.581e-166	538.0	COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,1JH5V@1189|Stigonemataceae	1117|Cyanobacteria	J	Amidase	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS2_k127_2466088_1	401526.TcarDRAFT_2181	7.515e-162	520.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H2JV@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS2_k127_2466088_3	1183438.GKIL_3572	1.14e-25	108.0	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS2_k127_2466088_2	338966.Ppro_1744	2.113e-77	266.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,43T1X@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	KR domain	fabG-2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS2_k127_2466088_4	426368.MmarC7_1645	1.824e-12	73.0	COG1397@1|root,arCOG04448@2157|Archaea,2XV15@28890|Euryarchaeota,23QAK@183939|Methanococci	183939|Methanococci	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
LZS2_k127_249801_3	1329516.JPST01000013_gene271	3.183e-77	267.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HCH3@91061|Bacilli,27BEI@186824|Thermoactinomycetaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS2_k127_249801_2	483219.LILAB_26940	1.548e-104	348.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,42Q6T@68525|delta/epsilon subdivisions,2WJP1@28221|Deltaproteobacteria,2YUHR@29|Myxococcales	28221|Deltaproteobacteria	E	HMGL-like	mvaB	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3293	HMGL-like
LZS2_k127_249801_5	1347086.CCBA010000030_gene161	8.479e-19	89.0	COG1038@1|root,COG1038@2|Bacteria,1UIWR@1239|Firmicutes,4ISV0@91061|Bacilli,1ZS6P@1386|Bacillus	91061|Bacilli	C	Biotin carboxyl carrier protein	yngHB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
LZS2_k127_249801_0	91464.S7335_4914	1.764e-272	863.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1G1A0@1117|Cyanobacteria,1GYF2@1129|Synechococcus	1117|Cyanobacteria	GJM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
LZS2_k127_249801_1	203119.Cthe_1303	4.611e-122	404.0	COG0297@1|root,COG0297@2|Bacteria,1UHYC@1239|Firmicutes,24ANR@186801|Clostridia,3WKQE@541000|Ruminococcaceae	186801|Clostridia	G	Starch synthase catalytic	-	-	2.4.1.11	ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_249801_4	1173029.JH980292_gene906	4.072e-38	146.0	COG0240@1|root,COG0240@2|Bacteria,1G0M0@1117|Cyanobacteria,1H7NR@1150|Oscillatoriales	1117|Cyanobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	iJN678.gpsA	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
LZS2_k127_252000_3	868864.Dester_0466	7.16e-36	138.0	COG0143@1|root,COG0143@2|Bacteria,2G3J0@200783|Aquificae	200783|Aquificae	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
LZS2_k127_252000_0	401526.TcarDRAFT_2084	2.01e-107	363.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4H27H@909932|Negativicutes	909932|Negativicutes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
LZS2_k127_252000_6	316067.Geob_0828	0.0001353	49.0	COG4980@1|root,COG4980@2|Bacteria,1NB49@1224|Proteobacteria,42W0M@68525|delta/epsilon subdivisions,2WRVH@28221|Deltaproteobacteria,43SQE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS2_k127_252000_5	558169.AGAV01000025_gene53	9.515e-05	50.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli	91061|Bacilli	S	General stress protein	ytxH	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS2_k127_252000_1	1128427.KB904821_gene3338	1.315e-63	243.0	COG0265@1|root,COG0457@1|root,COG3063@1|root,COG4995@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,COG3063@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_252000_2	1206744.BAGL01000002_gene4279	5.687e-56	217.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FU85@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_252000_4	1123242.JH636434_gene4582	6.592e-15	84.0	COG0204@1|root,COG0204@2|Bacteria,2IZHN@203682|Planctomycetes	203682|Planctomycetes	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS2_k127_2531392_0	1403819.BATR01000112_gene3737	1.838e-43	173.0	COG2319@1|root,COG2319@2|Bacteria,46THG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4034)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4034
LZS2_k127_2531392_1	1163617.SCD_n02994	2.136e-05	56.0	COG0457@1|root,COG3063@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria	28216|Betaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
LZS2_k127_2563475_1	420324.KI911965_gene1249	9.758e-09	59.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2U33F@28211|Alphaproteobacteria,1JUP1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1223)	MA20_43790	-	-	-	-	-	-	-	-	-	-	-	DUF1223
LZS2_k127_2563475_0	913848.AELK01000182_gene917	7.207e-28	127.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_2568277_1	1480694.DC28_07915	0.0004998	52.0	COG1752@1|root,COG1752@2|Bacteria,2J6JW@203691|Spirochaetes	203691|Spirochaetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
LZS2_k127_2568277_0	290397.Adeh_2886	3.21e-76	279.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
LZS2_k127_25726_0	247490.KSU1_C1131	4.367e-45	169.0	COG1881@1|root,COG1881@2|Bacteria,2J1MM@203682|Planctomycetes	203682|Planctomycetes	G	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP,YHYH
LZS2_k127_25726_1	767817.Desgi_1238	3.103e-05	57.0	COG0265@1|root,COG0265@2|Bacteria,1UZ3Q@1239|Firmicutes	1239|Firmicutes	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
LZS2_k127_258987_1	378806.STAUR_1095	1.83e-13	77.0	COG2304@1|root,COG2304@2|Bacteria,1MX4C@1224|Proteobacteria,439DU@68525|delta/epsilon subdivisions,2X4NR@28221|Deltaproteobacteria,2YZBD@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
LZS2_k127_258987_0	439375.Oant_1781	1.346e-14	80.0	28NEI@1|root,2ZBH3@2|Bacteria,1NPBX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2597425_0	1122931.AUAE01000001_gene774	0.0001701	52.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22XN2@171551|Porphyromonadaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
LZS2_k127_2600994_0	251229.Chro_4139	1.411e-51	194.0	COG1398@1|root,COG1398@2|Bacteria,1G100@1117|Cyanobacteria,3VITB@52604|Pleurocapsales	1117|Cyanobacteria	I	PFAM Fatty acid desaturase	ole1	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS2_k127_2600994_1	864702.OsccyDRAFT_0253	1.04e-09	65.0	COG0745@1|root,COG0745@2|Bacteria,1G027@1117|Cyanobacteria,1H7ZK@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg,Trans_reg_C
LZS2_k127_2603422_0	1132442.KB889752_gene2715	2.883e-116	386.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,4HFM9@91061|Bacilli,1ZB5F@1386|Bacillus	91061|Bacilli	E	Aspartate ammonia-lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS2_k127_2603422_1	411490.ANACAC_00119	0.0001761	52.0	COG3063@1|root,COG3063@2|Bacteria,1UY48@1239|Firmicutes,24AGF@186801|Clostridia	186801|Clostridia	NU	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_260410_3	333138.LQ50_18175	2.204e-68	238.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_260410_6	1343739.PAP_03080	4.64e-26	112.0	COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci	183968|Thermococci	J	Endoribonuclease L-PSP	-	GO:0003674,GO:0003824,GO:0016787,GO:0019239	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS2_k127_260410_5	66692.ABC0652	8.809e-37	147.0	COG1878@1|root,COG1878@2|Bacteria,1U801@1239|Firmicutes,4HDQ3@91061|Bacilli,1ZD77@1386|Bacillus	91061|Bacilli	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
LZS2_k127_260410_2	1168034.FH5T_08655	4.978e-69	243.0	COG0434@1|root,COG0434@2|Bacteria,4P0R6@976|Bacteroidetes	976|Bacteroidetes	S	BtpA family	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
LZS2_k127_260410_1	1242864.D187_010069	1.062e-71	261.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
LZS2_k127_260410_0	329726.AM1_1675	1.313e-74	266.0	COG1195@1|root,COG1195@2|Bacteria,1G1F6@1117|Cyanobacteria	1117|Cyanobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
LZS2_k127_260410_4	273068.TTE1389	2.44e-63	229.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,42F98@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
LZS2_k127_260749_0	1178540.BA70_18035	7.138e-19	89.0	COG0861@1|root,COG0861@2|Bacteria,1TQ09@1239|Firmicutes,4IRR9@91061|Bacilli,1ZD3U@1386|Bacillus	91061|Bacilli	P	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TerC
LZS2_k127_260749_1	926569.ANT_01600	2.706e-18	91.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
LZS2_k127_260749_2	42256.RradSPS_3078	0.0001754	45.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
LZS2_k127_2636917_0	1000565.METUNv1_00214	0.0	1236.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,2KUK2@206389|Rhodocyclales	206389|Rhodocyclales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
LZS2_k127_2636917_1	765913.ThidrDRAFT_4303	4.36e-188	594.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,1WWJN@135613|Chromatiales	135613|Chromatiales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
LZS2_k127_2636917_2	1123405.AUMM01000009_gene1182	1.895e-180	577.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,26NKM@186821|Sporolactobacillaceae	91061|Bacilli	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
LZS2_k127_2640520_1	926569.ANT_11490	1.048e-15	91.0	COG1807@1|root,COG1807@2|Bacteria,2G9HX@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2640520_0	926569.ANT_15160	1.413e-64	236.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
LZS2_k127_264218_3	696747.NIES39_L06080	6.281e-22	102.0	COG0492@1|root,COG0526@1|root,COG0492@2|Bacteria,COG0526@2|Bacteria,1G15I@1117|Cyanobacteria,1H96A@1150|Oscillatoriales	1117|Cyanobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
LZS2_k127_264218_1	1123304.AQYA01000037_gene454	5.556e-63	224.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli	91061|Bacilli	F	gtp cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
LZS2_k127_264218_0	1242864.D187_010412	6.342e-82	286.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,42MR3@68525|delta/epsilon subdivisions,2WKWG@28221|Deltaproteobacteria,2YTTA@29|Myxococcales	28221|Deltaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
LZS2_k127_264218_2	378806.STAUR_0437	5.551e-32	128.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,42MR3@68525|delta/epsilon subdivisions,2WKWG@28221|Deltaproteobacteria,2YTTA@29|Myxococcales	28221|Deltaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
LZS2_k127_2642383_0	1173021.ALWA01000019_gene502	1.292e-153	502.0	COG5267@1|root,COG5267@2|Bacteria,1G0JB@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
LZS2_k127_2642383_1	179408.Osc7112_3314	9.021e-138	449.0	COG4102@1|root,COG4102@2|Bacteria,1G2W5@1117|Cyanobacteria,1H8H7@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS2_k127_2642383_2	111780.Sta7437_2511	2.734e-41	164.0	2953F@1|root,2ZSG5@2|Bacteria,1G5RU@1117|Cyanobacteria,3VMHV@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2655029_0	880073.Calab_1349	4.333e-33	135.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS2_k127_2655029_1	879212.DespoDRAFT_00792	4.891e-17	85.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,2MKAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
LZS2_k127_2655186_1	1030157.AFMP01000059_gene2792	1.321e-67	235.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2U7R3@28211|Alphaproteobacteria,2K47B@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the glutathione peroxidase family	gpo	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
LZS2_k127_2655186_2	42256.RradSPS_3058	1.087e-51	198.0	COG1503@1|root,COG1503@2|Bacteria	2|Bacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2655186_0	414996.IL38_19300	1.364e-131	434.0	COG0471@1|root,COG0471@2|Bacteria,2GVHZ@201174|Actinobacteria,407ZE@622450|Actinopolysporales	201174|Actinobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS2_k127_2664438_0	1131266.ARWQ01000002_gene454	2.869e-43	172.0	COG0308@1|root,arCOG02969@2157|Archaea,41SJH@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256,ko:K13722	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
LZS2_k127_2664438_1	1150474.JQJI01000005_gene283	5.179e-27	123.0	COG1752@1|root,COG1752@2|Bacteria,2GCZ9@200918|Thermotogae	200918|Thermotogae	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS2_k127_2664438_2	395965.Msil_2286	1.022e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,1NG0U@1224|Proteobacteria,2U0YA@28211|Alphaproteobacteria,3N9KN@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_2671794_1	216591.pBCA041	2.071e-08	68.0	COG3451@1|root,COG3451@2|Bacteria,1MUEN@1224|Proteobacteria,2VHPD@28216|Betaproteobacteria,1K53B@119060|Burkholderiaceae	28216|Betaproteobacteria	U	F pilus assembly Type-IV secretion system for plasmid transfer	traC	-	-	ko:K12063	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	AAA_10,TraC_F_IV
LZS2_k127_2671794_0	1450694.BTS2_3344	2.663e-10	74.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,4H9ZN@91061|Bacilli,1ZCTB@1386|Bacillus	91061|Bacilli	U	TraM recognition site of TraD and TraG	traK	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
LZS2_k127_2679806_0	1499967.BAYZ01000173_gene5813	5.758e-131	449.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
LZS2_k127_26907_0	1313172.YM304_33630	6.598e-111	384.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1,Thiol-ester_cl
LZS2_k127_2691482_1	1123376.AUIU01000018_gene50	5.424e-94	323.0	COG0668@1|root,COG0668@2|Bacteria,3J0YK@40117|Nitrospirae	40117|Nitrospirae	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
LZS2_k127_2691482_2	696369.KI912183_gene1919	1.25e-30	128.0	COG0288@1|root,COG0288@2|Bacteria,1VSV8@1239|Firmicutes,24GE5@186801|Clostridia,2652J@186807|Peptococcaceae	186801|Clostridia	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
LZS2_k127_2691482_6	2074.JNYD01000049_gene774	9.355e-05	52.0	2EDMI@1|root,337HC@2|Bacteria,2GYPQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2691482_4	436114.SYO3AOP1_0336	4.244e-08	66.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_2691482_3	1385935.N836_14920	3.292e-20	101.0	COG2267@1|root,COG4188@1|root,COG2267@2|Bacteria,COG4188@2|Bacteria,1G2EN@1117|Cyanobacteria,1H7RF@1150|Oscillatoriales	1117|Cyanobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_2691482_0	880073.Calab_3204	5.73e-130	437.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
LZS2_k127_2691482_5	1463845.JOIG01000005_gene3542	6.103e-05	55.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	-
LZS2_k127_2701017_0	1487923.DP73_10175	1.523e-69	260.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,260IK@186807|Peptococcaceae	186801|Clostridia	J	Elongation factor Tu domain 2	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
LZS2_k127_2705014_0	765952.PUV_16740	5.579e-132	436.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	alkA	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003905,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008725,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0032131,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0043733,GO:0043916,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	2.1.1.63,3.2.2.21	ko:K00567,ko:K01247,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
LZS2_k127_2705014_2	1131730.BAVI_05499	6.617e-34	137.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HKC0@91061|Bacilli,1ZGW4@1386|Bacillus	91061|Bacilli	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
LZS2_k127_2705014_1	102129.Lepto7375DRAFT_0018	3.838e-48	192.0	COG1002@1|root,COG1002@2|Bacteria	2|Bacteria	V	DNA modification	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2705278_5	404380.Gbem_0525	0.0009059	51.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2WIP4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
LZS2_k127_2705278_3	1079986.JH164837_gene5639	6.963e-07	61.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_2705278_4	883126.HMPREF9710_03593	1.521e-05	57.0	COG2204@1|root,COG5001@1|root,COG2204@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,PAS_7,Response_reg
LZS2_k127_2705278_2	321327.CYA_0371	2.072e-25	106.0	COG1146@1|root,COG1146@2|Bacteria,1G7Q8@1117|Cyanobacteria,1H10K@1129|Synechococcus	1117|Cyanobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_2,Fer4_7
LZS2_k127_2705278_1	1450694.BTS2_0558	3.193e-30	121.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli,1ZH7M@1386|Bacillus	91061|Bacilli	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
LZS2_k127_2705278_0	1209989.TepiRe1_1387	2.224e-76	265.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,42F53@68295|Thermoanaerobacterales	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
LZS2_k127_2709387_1	42256.RradSPS_2982	1.42e-14	82.0	COG2105@1|root,COG2105@2|Bacteria,2GV2B@201174|Actinobacteria	201174|Actinobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
LZS2_k127_2709387_0	1382306.JNIM01000001_gene1266	3.736e-23	102.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS2_k127_272537_0	452637.Oter_4631	1.248e-11	69.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_2732970_1	46234.ANA_C11566	4.243e-27	130.0	COG0612@1|root,COG0612@2|Bacteria,1G3GH@1117|Cyanobacteria,1HIEH@1161|Nostocales	1117|Cyanobacteria	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_2732970_0	1449126.JQKL01000017_gene2750	4.696e-145	478.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,2684P@186813|unclassified Clostridiales	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
LZS2_k127_2753893_1	177437.HRM2_08750	3.125e-109	370.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2MPTW@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS2_k127_2753893_0	1267535.KB906767_gene3344	7.934e-122	399.0	COG0276@1|root,COG0276@2|Bacteria,3Y3B0@57723|Acidobacteria,2JHKQ@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
LZS2_k127_2767831_1	926550.CLDAP_08760	3.493e-29	122.0	COG0838@1|root,COG0838@2|Bacteria,2G78Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
LZS2_k127_2767831_0	926561.KB900622_gene593	2.29e-43	168.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3WAJK@53433|Halanaerobiales	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
LZS2_k127_2770177_2	13035.Dacsa_0088	9.539e-29	119.0	COG2367@1|root,COG2367@2|Bacteria,1G06I@1117|Cyanobacteria	1117|Cyanobacteria	V	Beta-lactamase class A	ampC	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
LZS2_k127_2770177_4	272123.Anacy_1562	6.06e-16	86.0	COG0711@1|root,COG0711@2|Bacteria,1GHFG@1117|Cyanobacteria,1HUBG@1161|Nostocales	1117|Cyanobacteria	C	COG3599 Cell division initiation protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2770177_1	13035.Dacsa_0915	5.191e-52	188.0	COG0669@1|root,COG0669@2|Bacteria,1G4Z8@1117|Cyanobacteria	1117|Cyanobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS2_k127_2770177_0	195253.Syn6312_2615	2.505e-89	319.0	COG5002@1|root,COG5002@2|Bacteria,1FZWA@1117|Cyanobacteria,1GYZN@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase	nblS	-	2.7.13.3	ko:K07769	ko02020,map02020	M00466	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
LZS2_k127_2770177_3	1157640.AQWO01000015_gene1164	3.99e-17	85.0	COG1191@1|root,COG1191@2|Bacteria,2ICHH@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_2771753_1	880073.Calab_1807	0.0006041	51.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	zraP	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897	-	ko:K07803	ko02020,map02020	-	-	-	ko00000,ko00001,ko03110	-	-	-	Metal_resist
LZS2_k127_2771753_0	1123023.JIAI01000009_gene1173	6.715e-26	111.0	COG1540@1|root,COG1540@2|Bacteria,2GJA1@201174|Actinobacteria,4DXTK@85010|Pseudonocardiales	2|Bacteria	S	Belongs to the UPF0271 (lamB) family	lamB	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
LZS2_k127_2780312_4	1131462.DCF50_p1897	1.686e-37	143.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,26186@186807|Peptococcaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
LZS2_k127_2780312_1	1173025.GEI7407_0782	3.432e-64	226.0	COG0087@1|root,COG0087@2|Bacteria,1FZY5@1117|Cyanobacteria,1H7IS@1150|Oscillatoriales	1117|Cyanobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rpl3	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
LZS2_k127_2780312_3	395961.Cyan7425_0707	3.925e-43	161.0	COG0051@1|root,COG0051@2|Bacteria,1G5TJ@1117|Cyanobacteria,3KHZR@43988|Cyanothece	1117|Cyanobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
LZS2_k127_2780312_0	676032.FN3523_1640	7.436e-202	634.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS2_k127_2780312_2	1121121.KB894322_gene398	6.656e-52	198.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,26RQZ@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
LZS2_k127_2782080_0	42256.RradSPS_2906	3.834e-121	410.0	COG2898@1|root,COG2898@2|Bacteria,2I2ZR@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	2.3.2.3,6.1.1.6	ko:K04567,ko:K14205	ko00970,ko01503,ko02020,ko05150,map00970,map01503,map02020,map05150	M00359,M00360,M00726	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko01504,ko03016	2.A.1.3.37	-	-	DUF2156,tRNA-synt_2_TM
LZS2_k127_2792262_0	402777.KB235903_gene1873	5.539e-161	531.0	COG1203@1|root,COG1203@2|Bacteria,1G1UD@1117|Cyanobacteria,1H9DV@1150|Oscillatoriales	1117|Cyanobacteria	L	DEAD-like helicases superfamily	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
LZS2_k127_2792262_1	1173026.Glo7428_3079	7.97e-19	90.0	28JJV@1|root,2Z9CT@2|Bacteria,1G4MM@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2794708_0	909613.UO65_5768	1.667e-26	121.0	COG3953@1|root,COG3953@2|Bacteria,2HBQA@201174|Actinobacteria,4DYK3@85010|Pseudonocardiales	201174|Actinobacteria	N	Belongs to the WXG100 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4226,SLT,WXG100
LZS2_k127_2794708_1	595460.RRSWK_06787	0.000842	46.0	COG3449@1|root,COG3449@2|Bacteria,2J2ST@203682|Planctomycetes	203682|Planctomycetes	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
LZS2_k127_2795857_2	1131269.AQVV01000006_gene504	1.403e-21	96.0	COG0137@1|root,COG0137@2|Bacteria	2|Bacteria	E	argininosuccinate synthase activity	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
LZS2_k127_2795857_0	500635.MITSMUL_03594	3.827e-111	374.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4H23K@909932|Negativicutes	909932|Negativicutes	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
LZS2_k127_2795857_1	1304284.L21TH_0674	1.39e-58	213.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,36DBS@31979|Clostridiaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_2799503_1	1288963.ADIS_2755	1.94e-09	61.0	COG1846@1|root,COG2865@1|root,COG1846@2|Bacteria,COG2865@2|Bacteria,4NGFJ@976|Bacteroidetes,47U24@768503|Cytophagia	976|Bacteroidetes	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
LZS2_k127_2799503_0	1435356.Y013_22775	6.194e-14	77.0	COG1051@1|root,COG1051@2|Bacteria,2IQEA@201174|Actinobacteria,4G0XN@85025|Nocardiaceae	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	mutT2	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_2805928_2	679926.Mpet_0142	6.2e-10	64.0	COG0835@1|root,arCOG02395@2157|Archaea,2XX4H@28890|Euryarchaeota	28890|Euryarchaeota	N	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS2_k127_2805928_0	269799.Gmet_2707	3.461e-82	293.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1R6N1@1224|Proteobacteria,42NZW@68525|delta/epsilon subdivisions,2WMDS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM MCP methyltransferase, CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16,TPR_8
LZS2_k127_2805928_1	1396418.BATQ01000049_gene413	5.453e-61	224.0	COG0840@1|root,COG0840@2|Bacteria,46TVU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
LZS2_k127_2805928_3	1042163.BRLA_c037620	3.711e-07	57.0	COG0835@1|root,COG0835@2|Bacteria,1V431@1239|Firmicutes,4IRQE@91061|Bacilli	91061|Bacilli	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS2_k127_2809425_0	243365.CV_1562	1.085e-108	366.0	COG1010@1|root,COG2099@1|root,COG1010@2|Bacteria,COG2099@2|Bacteria,1MU79@1224|Proteobacteria,2VIG5@28216|Betaproteobacteria,2KQGN@206351|Neisseriales	206351|Neisseriales	H	precorrin-3B C17-methyltransferase	-	-	2.1.1.131	ko:K05934	ko00860,ko01100,map00860,map01100	-	R05180,R05809	RC00003,RC01293,RC03471	ko00000,ko00001,ko01000	-	-	-	CbiJ,TP_methylase
LZS2_k127_2809425_1	748280.NH8B_1833	3.055e-77	267.0	COG2073@1|root,COG2073@2|Bacteria,1MWE6@1224|Proteobacteria,2VNAH@28216|Betaproteobacteria,2KPRV@206351|Neisseriales	206351|Neisseriales	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N
LZS2_k127_2809425_2	937777.Deipe_2310	1.612e-76	264.0	COG2875@1|root,COG2875@2|Bacteria,1WIV3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cbiF	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
LZS2_k127_2817238_0	1192034.CAP_6830	3.248e-53	205.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_281794_0	886293.Sinac_3564	9.404e-146	480.0	COG0659@1|root,COG0659@2|Bacteria,2IXYR@203682|Planctomycetes	203682|Planctomycetes	P	Sulfate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
LZS2_k127_281794_1	1158338.JNLJ01000001_gene1090	7.471e-40	153.0	COG5002@1|root,COG5002@2|Bacteria,2G40K@200783|Aquificae	200783|Aquificae	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
LZS2_k127_2823292_0	717605.Theco_2614	4.414e-42	156.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,26RV3@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS2_k127_2823292_2	383372.Rcas_3447	1.219e-35	145.0	COG1714@1|root,COG1714@2|Bacteria,2G7CB@200795|Chloroflexi,375N6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
LZS2_k127_2823292_1	357808.RoseRS_3801	7.049e-40	157.0	COG1300@1|root,COG1300@2|Bacteria,2G8HV@200795|Chloroflexi,37546@32061|Chloroflexia	32061|Chloroflexia	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
LZS2_k127_2823845_2	6500.XP_005094954.1	0.0001517	53.0	COG0457@1|root,KOG1840@2759|Eukaryota,38GPH@33154|Opisthokonta,3BE82@33208|Metazoa,3CWCE@33213|Bilateria	33208|Metazoa	Z	cellular localization	APPBP2	GO:0000003,GO:0000578,GO:0003002,GO:0003006,GO:0003674,GO:0003774,GO:0003777,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005856,GO:0005871,GO:0005875,GO:0006403,GO:0006810,GO:0006886,GO:0006928,GO:0007017,GO:0007018,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007314,GO:0007315,GO:0007316,GO:0007350,GO:0007351,GO:0007389,GO:0008104,GO:0008150,GO:0008298,GO:0008358,GO:0008595,GO:0009790,GO:0009798,GO:0009880,GO:0009948,GO:0009952,GO:0009987,GO:0009994,GO:0012506,GO:0015031,GO:0015630,GO:0015833,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019094,GO:0019953,GO:0021700,GO:0022412,GO:0022414,GO:0022607,GO:0030154,GO:0030659,GO:0031090,GO:0031410,GO:0031982,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032886,GO:0032991,GO:0033036,GO:0034613,GO:0035282,GO:0042886,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044085,GO:0044422,GO:0044424,GO:0044430,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045184,GO:0045451,GO:0046907,GO:0048468,GO:0048469,GO:0048477,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0051270,GO:0051641,GO:0051649,GO:0051704,GO:0060632,GO:0060810,GO:0060811,GO:0065007,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0097708	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12
LZS2_k127_2823845_1	1123508.JH636440_gene2613	8.567e-08	58.0	29GQM@1|root,2ZS2M@2|Bacteria,2J0EP@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4419)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4419
LZS2_k127_2823845_0	1458275.AZ34_11660	3.373e-32	128.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,2VIX6@28216|Betaproteobacteria,4ABDH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese
LZS2_k127_2836833_1	710687.KI912270_gene6267	3.689e-06	56.0	2AQYW@1|root,31G7K@2|Bacteria,2IEZS@201174|Actinobacteria,236WT@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2836833_0	1333998.M2A_1721	1.283e-10	73.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2TV6U@28211|Alphaproteobacteria,4BS3R@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_2836833_2	82508.K1VUF6	3.648e-05	51.0	KOG1947@1|root,KOG1947@2759|Eukaryota,3929C@33154|Opisthokonta,3NZ1M@4751|Fungi,3UYN0@5204|Basidiomycota,3VDYN@5234|Tremellales	4751|Fungi	S	Leucine-rich repeats, outliers	RAD7	GO:0000109,GO:0000113,GO:0000151,GO:0000715,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006281,GO:0006289,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0031461,GO:0031463,GO:0032991,GO:0033036,GO:0033554,GO:0034613,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051179,GO:0051276,GO:0051641,GO:0051716,GO:0070727,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1902494,GO:1990234,GO:1990391	-	ko:K15082	-	-	-	-	ko00000,ko03400	-	-	-	LRR_6
LZS2_k127_2837467_6	748449.Halha_2029	2.329e-27	121.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WB91@53433|Halanaerobiales	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
LZS2_k127_2837467_5	1158318.ATXC01000001_gene1441	3.118e-87	294.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS2_k127_2837467_2	251221.35214770	1.687e-190	603.0	COG1219@1|root,COG1219@2|Bacteria,1G04H@1117|Cyanobacteria	1117|Cyanobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
LZS2_k127_2837467_0	635013.TherJR_2560	4.907e-264	835.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,260BY@186807|Peptococcaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS2_k127_2837467_3	56780.SYN_01215	1.607e-129	427.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_2837467_1	1379698.RBG1_1C00001G0471	3.784e-205	649.0	COG1012@1|root,COG1012@2|Bacteria,2NNR8@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	ycbD	-	1.2.1.3	ko:K00128,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_2837467_4	235909.GK0445	1.586e-102	342.0	COG1960@1|root,COG1960@2|Bacteria,1TPVK@1239|Firmicutes,4HA7B@91061|Bacilli,1WERN@129337|Geobacillus	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_2871171_0	203119.Cthe_1282	3.127e-47	187.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24H33@186801|Clostridia,3WI55@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
LZS2_k127_2883876_1	795797.C497_00955	1.209e-14	81.0	COG0318@1|root,arCOG00856@2157|Archaea,2XSZG@28890|Euryarchaeota,23T2E@183963|Halobacteria	183963|Halobacteria	I	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS2_k127_2883876_0	1122927.KB895421_gene4001	2.222e-158	526.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli,26QZH@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
LZS2_k127_2883876_3	935261.JAGL01000012_gene3466	8.604e-07	62.0	COG0457@1|root,COG1388@1|root,COG0457@2|Bacteria,COG1388@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,43JDF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Tetratricopeptide repeat	MA20_42300	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
LZS2_k127_2883876_2	32264.tetur11g03550.1	1.561e-11	74.0	COG0526@1|root,KOG0910@2759|Eukaryota,3A8MT@33154|Opisthokonta,3BT0I@33208|Metazoa,3D9I0@33213|Bilateria,42A2W@6656|Arthropoda	33208|Metazoa	O	protein disulfide oxidoreductase activity. It is involved in the biological process described with	TXN2	GO:0000096,GO:0000098,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009605,GO:0009611,GO:0009628,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0015036,GO:0016054,GO:0016491,GO:0016667,GO:0019752,GO:0030425,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0034284,GO:0036293,GO:0036477,GO:0042221,GO:0042493,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044877,GO:0046395,GO:0048678,GO:0050896,GO:0051716,GO:0055114,GO:0070013,GO:0070482,GO:0071496,GO:0071704,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:1901564,GO:1901565,GO:1901575,GO:1901700	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_2883876_4	1048983.EL17_19325	0.000164	49.0	COG2267@1|root,COG2267@2|Bacteria,4NIU9@976|Bacteroidetes,47PWX@768503|Cytophagia	976|Bacteroidetes	I	Serine aminopeptidase, S33	ytpA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_288782_1	56110.Oscil6304_5254	1.816e-55	199.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1HB1V@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
LZS2_k127_288782_0	95619.PM1_0216740	5.959e-74	263.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_2894990_3	1236976.JCM16418_4521	2.474e-28	122.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_2894990_2	1121859.KB890741_gene3748	6.729e-34	142.0	COG0077@1|root,COG0077@2|Bacteria,4NEEK@976|Bacteroidetes,47NM0@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
LZS2_k127_2894990_1	272123.Anacy_3355	2.63e-69	249.0	COG0337@1|root,COG0337@2|Bacteria,1G03C@1117|Cyanobacteria,1HIJQ@1161|Nostocales	1117|Cyanobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
LZS2_k127_2894990_0	574087.Acear_1758	6.577e-74	257.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WACY@53433|Halanaerobiales	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
LZS2_k127_2897114_0	10224.XP_006823305.1	1.507e-07	59.0	KOG0547@1|root,KOG0547@2759|Eukaryota,38BB8@33154|Opisthokonta,3BE1Z@33208|Metazoa,3CRIM@33213|Bilateria	33208|Metazoa	U	negative regulation of cell growth involved in cardiac muscle cell development	TOMM70A	GO:0001101,GO:0001558,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005742,GO:0006605,GO:0006626,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010243,GO:0010611,GO:0010614,GO:0010721,GO:0014070,GO:0014741,GO:0014743,GO:0015031,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016202,GO:0019867,GO:0022804,GO:0022857,GO:0022884,GO:0030308,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0040008,GO:0042221,GO:0042493,GO:0042886,GO:0042887,GO:0043200,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043502,GO:0044057,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045184,GO:0045595,GO:0045596,GO:0045843,GO:0045926,GO:0046620,GO:0046621,GO:0046907,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048634,GO:0048635,GO:0048638,GO:0048640,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051093,GO:0051128,GO:0051147,GO:0051148,GO:0051153,GO:0051154,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051241,GO:0051641,GO:0051649,GO:0055021,GO:0055022,GO:0055024,GO:0055026,GO:0055085,GO:0060284,GO:0060420,GO:0061050,GO:0061052,GO:0061117,GO:0065007,GO:0070201,GO:0070585,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072655,GO:0090087,GO:0090257,GO:0097066,GO:0097068,GO:0098573,GO:0098588,GO:0098796,GO:0098798,GO:0098799,GO:0098805,GO:1901698,GO:1901700,GO:1901861,GO:1901862,GO:1904386,GO:1904589,GO:1904591,GO:1904680,GO:1904951,GO:1905207,GO:1905208,GO:2000026,GO:2000725,GO:2000726	-	ko:K17768	-	-	-	-	ko00000,ko02000,ko03029	3.A.8.1	-	-	TPR_1,TPR_16,TPR_2,TPR_8
LZS2_k127_2897114_1	102129.Lepto7375DRAFT_2039	3.254e-07	62.0	COG0589@1|root,COG0589@2|Bacteria,1G895@1117|Cyanobacteria,1HBQ2@1150|Oscillatoriales	1117|Cyanobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_2897663_0	580327.Tthe_1520	1.227e-45	173.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_2905411_1	344747.PM8797T_27924	2.7e-138	446.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0042802,GO:0042803,GO:0043170,GO:0044238,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	iJN678.slr2001	Peptidase_S51
LZS2_k127_2905411_0	344747.PM8797T_27914	2.413e-220	692.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2IXGZ@203682|Planctomycetes	203682|Planctomycetes	M	cyanophycin synthetase	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS2_k127_2919357_5	1541065.JRFE01000022_gene4008	1.38e-12	74.0	COG2193@1|root,COG2193@2|Bacteria,1G50V@1117|Cyanobacteria,3VJY1@52604|Pleurocapsales	1117|Cyanobacteria	P	Bacterioferritin (cytochrome b1)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
LZS2_k127_2919357_1	1379698.RBG1_1C00001G0333	1.812e-111	375.0	COG1228@1|root,COG1228@2|Bacteria,2NNTC@2323|unclassified Bacteria	2|Bacteria	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS2_k127_2919357_3	1121405.dsmv_3719	2.748e-83	286.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2MI64@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_2919357_2	1303518.CCALI_01512	6.529e-97	328.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	yumC	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	iYO844.BSU32110	Pyr_redox_2,Pyr_redox_3
LZS2_k127_2919357_4	720554.Clocl_2259	1.517e-18	97.0	COG2159@1|root,COG2159@2|Bacteria,1V0B9@1239|Firmicutes,258X5@186801|Clostridia,3WNVC@541000|Ruminococcaceae	186801|Clostridia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS2_k127_2919357_0	565033.GACE_1702	1.959e-208	665.0	COG0209@1|root,arCOG04276@2157|Archaea,2XUBW@28890|Euryarchaeota,245VM@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
LZS2_k127_2922265_2	251221.35213737	4.236e-79	278.0	COG3408@1|root,COG3408@2|Bacteria,1G2J4@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Amylo-alpha-16-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
LZS2_k127_2922265_1	1303518.CCALI_00532	1.076e-88	305.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
LZS2_k127_2922265_0	234267.Acid_5819	8.551e-150	492.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
LZS2_k127_2922265_3	483219.LILAB_21145	9.978e-58	221.0	COG0312@1|root,COG0312@2|Bacteria,1Q3C0@1224|Proteobacteria,4393A@68525|delta/epsilon subdivisions,2X495@28221|Deltaproteobacteria,2YYIX@29|Myxococcales	28221|Deltaproteobacteria	S	peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
LZS2_k127_2931700_2	1541065.JRFE01000024_gene1039	9.791e-05	50.0	COG5548@1|root,COG5548@2|Bacteria,1G997@1117|Cyanobacteria,3VKTI@52604|Pleurocapsales	1117|Cyanobacteria	S	Transmembrane proteins 14C	-	-	-	-	-	-	-	-	-	-	-	-	Tmemb_14
LZS2_k127_2931700_0	118163.Ple7327_4480	1.928e-33	149.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,1G10B@1117|Cyanobacteria,3VJ4K@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
LZS2_k127_2931700_1	29875.EHK19877	3.474e-17	95.0	COG0457@1|root,KOG1840@2759|Eukaryota,39GQA@33154|Opisthokonta,3NWHJ@4751|Fungi,3QMSZ@4890|Ascomycota,21537@147550|Sordariomycetes,3TJJM@5125|Hypocreales,3U41S@5129|Hypocreaceae	4751|Fungi	Z	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,NB-ARC,TPR_10,TPR_12,TPR_4,TPR_7
LZS2_k127_2931993_2	1449080.JQMV01000006_gene2253	4.433e-14	77.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1WKIH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
LZS2_k127_2931993_1	588581.Cpap_4023	1.256e-17	94.0	2AA7Z@1|root,30ZH6@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4238)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4238
LZS2_k127_2931993_3	296587.XP_002506751.1	1.945e-11	70.0	2CMNS@1|root,2QR35@2759|Eukaryota,37P6X@33090|Viridiplantae,34IT8@3041|Chlorophyta	3041|Chlorophyta	L	Protein OSB2, chloroplastic-like	-	-	-	-	-	-	-	-	-	-	-	-	SSB
LZS2_k127_2935933_3	1117108.PAALTS15_27936	3.507e-14	72.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli,26RD2@186822|Paenibacillaceae	91061|Bacilli	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_2935933_2	180332.JTGN01000018_gene66	9.476e-17	84.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
LZS2_k127_2935933_1	1123368.AUIS01000009_gene2429	1.091e-37	158.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,2NBUH@225057|Acidithiobacillales	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4,YtkA
LZS2_k127_2935933_0	379066.GAU_2183	7.395e-113	379.0	COG3696@1|root,COG3696@2|Bacteria,1ZUB0@142182|Gemmatimonadetes	2|Bacteria	P	AcrB/AcrD/AcrF family	czcA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
LZS2_k127_2942627_0	1340493.JNIF01000003_gene3840	9.763e-203	652.0	COG1252@1|root,COG1252@2|Bacteria,3Y308@57723|Acidobacteria	2|Bacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,Pyr_redox_2,cNMP_binding
LZS2_k127_2942627_1	1242864.D187_006042	3.671e-60	229.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase,TonB_C
LZS2_k127_2942627_2	1297742.A176_06888	1.579e-56	218.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4346X@68525|delta/epsilon subdivisions,2XA3R@28221|Deltaproteobacteria,2YXWE@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TonB_C
LZS2_k127_2943060_1	1192034.CAP_6024	2.405e-151	487.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,42NGX@68525|delta/epsilon subdivisions,2WJC0@28221|Deltaproteobacteria,2YWXY@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAF987.Gmet_2434	E1-E2_ATPase,Hydrolase
LZS2_k127_2943060_0	671143.DAMO_0410	5.741e-230	728.0	COG2060@1|root,COG2060@2|Bacteria,2NP13@2323|unclassified Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAPECO1_1312.APECO1_1369,iECUMN_1333.ECUMN_0780,iYL1228.KPN_00717	KdpA
LZS2_k127_2943060_3	244582.JQAK01000045_gene2318	6.654e-17	81.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2TUNY@28211|Alphaproteobacteria,47FWE@766|Rickettsiales	766|Rickettsiales	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
LZS2_k127_2943060_2	387092.NIS_0310	1.47e-132	442.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
LZS2_k127_2943060_5	251229.Chro_3031	0.0007022	51.0	COG3264@1|root,COG3264@2|Bacteria,1G2UD@1117|Cyanobacteria,3VJ32@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_2943060_4	240016.ABIZ01000001_gene5379	7.678e-11	62.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	cadA	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
LZS2_k127_2945645_0	290397.Adeh_2448	1.572e-107	359.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,42YEF@68525|delta/epsilon subdivisions,2WU92@28221|Deltaproteobacteria,2YYRX@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
LZS2_k127_2945645_1	1120985.AUMI01000011_gene541	6.807e-23	105.0	COG3271@1|root,COG3271@2|Bacteria,1VAKE@1239|Firmicutes,4H81P@909932|Negativicutes	909932|Negativicutes	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2945645_3	237368.SCABRO_00307	9.692e-09	64.0	COG0260@1|root,COG0260@2|Bacteria,2IY4Q@203682|Planctomycetes	203682|Planctomycetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
LZS2_k127_2945645_2	1121013.P873_01180	1.164e-09	63.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1X49X@135614|Xanthomonadales	135614|Xanthomonadales	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS2_k127_2945853_2	309799.DICTH_1557	1.011e-06	61.0	COG0745@1|root,COG0745@2|Bacteria	309799.DICTH_1557|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2945853_1	471855.Shel_05910	2.761e-07	60.0	COG5330@1|root,COG5330@2|Bacteria,2HBF0@201174|Actinobacteria	201174|Actinobacteria	S	Leucine rich repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_2945853_3	1226322.HMPREF1545_01261	2.929e-05	49.0	2EHZK@1|root,33BR3@2|Bacteria,1VKWR@1239|Firmicutes,24U7R@186801|Clostridia,2N7X2@216572|Oscillospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2945853_0	43989.cce_2451	1.214e-12	72.0	2AETM@1|root,314QQ@2|Bacteria,1G6R9@1117|Cyanobacteria,3KI65@43988|Cyanothece	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2949468_1	864702.OsccyDRAFT_4349	1.068e-63	220.0	COG0048@1|root,COG0048@2|Bacteria,1G4ZZ@1117|Cyanobacteria,1HAP5@1150|Oscillatoriales	1117|Cyanobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
LZS2_k127_2949468_2	1541065.JRFE01000050_gene3028	5.099e-55	196.0	COG0049@1|root,COG0049@2|Bacteria,1G4ZX@1117|Cyanobacteria,3VJNQ@52604|Pleurocapsales	1117|Cyanobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rps7	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
LZS2_k127_2949468_0	1387197.AWGA01000055_gene1478	1.552e-275	867.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS2_k127_2949468_3	1120973.AQXL01000125_gene3127	8.807e-33	140.0	COG4102@1|root,COG4102@2|Bacteria,1VDF3@1239|Firmicutes,4HV1I@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS2_k127_2954457_0	76114.ebA4040	4.347e-266	832.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,2KV5X@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
LZS2_k127_2954457_2	485913.Krac_0189	4.455e-72	256.0	COG0196@1|root,COG3172@1|root,COG0196@2|Bacteria,COG3172@2|Bacteria,2G8Z0@200795|Chloroflexi	200795|Chloroflexi	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
LZS2_k127_2954457_1	402777.KB235903_gene1488	2.777e-85	292.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,1H7Y9@1150|Oscillatoriales	2|Bacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_2955714_0	755178.Cyan10605_2814	0.0	1226.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1G02W@1117|Cyanobacteria	1117|Cyanobacteria	EQ	N-methylhydantoinase B acetone carboxylase alpha subunit	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
LZS2_k127_2955714_1	525904.Tter_1472	1.185e-34	140.0	COG1533@1|root,COG1533@2|Bacteria,2NPK6@2323|unclassified Bacteria	2|Bacteria	L	Elongator protein 3, MiaB family, Radical SAM	M1-769	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_2957783_2	509190.Cseg_4067	3.576e-05	52.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2,START
LZS2_k127_2957783_3	714943.Mucpa_6173	0.000946	51.0	COG0823@1|root,COG3291@1|root,COG4447@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,4PHGX@976|Bacteroidetes,1IVRN@117747|Sphingobacteriia	976|Bacteroidetes	U	Cell surface receptor IPT TIG domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG,VCBS
LZS2_k127_2957783_1	1158345.JNLL01000001_gene1582	2.65e-54	198.0	COG1853@1|root,COG1853@2|Bacteria,2G45J@200783|Aquificae	200783|Aquificae	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
LZS2_k127_2957783_0	1487953.JMKF01000053_gene1837	8.534e-141	455.0	COG0389@1|root,COG0389@2|Bacteria,1G21I@1117|Cyanobacteria	1117|Cyanobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
LZS2_k127_2961778_0	349161.Dred_0015	3.228e-140	457.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,260VV@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
LZS2_k127_2961778_2	525256.HMPREF0091_10762	1.554e-12	75.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4CWB7@84998|Coriobacteriia	84998|Coriobacteriia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
LZS2_k127_2961778_1	111781.Lepto7376_4503	3.52e-124	411.0	COG0019@1|root,COG0019@2|Bacteria,1G1S7@1117|Cyanobacteria,1H71V@1150|Oscillatoriales	1117|Cyanobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
LZS2_k127_2965881_1	388467.A19Y_2309	4.087e-24	115.0	COG4249@1|root,COG4249@2|Bacteria,1G9TD@1117|Cyanobacteria	1117|Cyanobacteria	KLT	protein containing caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
LZS2_k127_2965881_0	1280946.HY29_04965	1.144e-28	125.0	28IYH@1|root,2Z8W7@2|Bacteria,1PDS3@1224|Proteobacteria,2U50V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (Hypoth_ymh)	-	-	-	-	-	-	-	-	-	-	-	-	Hypoth_Ymh
LZS2_k127_2965881_2	1382359.JIAL01000001_gene450	5.293e-06	59.0	COG2948@1|root,COG2948@2|Bacteria,3Y81Q@57723|Acidobacteria,2JN9S@204432|Acidobacteriia	204432|Acidobacteriia	U	multi-organism process	-	-	-	ko:K03195	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbI
LZS2_k127_2976570_0	760568.Desku_3566	4.083e-198	635.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,2601R@186807|Peptococcaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
LZS2_k127_2982508_0	1297742.A176_07282	1.09e-69	246.0	COG3220@1|root,COG3220@2|Bacteria	2|Bacteria	C	belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
LZS2_k127_2982508_1	448385.sce1886	6.986e-23	108.0	COG1746@1|root,COG1746@2|Bacteria,1RKKB@1224|Proteobacteria	1224|Proteobacteria	J	tRNA cytidylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
LZS2_k127_2982508_2	519989.ECTPHS_07137	1.7e-21	100.0	COG1714@1|root,COG1714@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,1WZR8@135613|Chromatiales	135613|Chromatiales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
LZS2_k127_2982508_3	118161.KB235922_gene3023	5.072e-06	56.0	COG1649@1|root,COG1649@2|Bacteria,1G2UW@1117|Cyanobacteria,3VJ7K@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
LZS2_k127_2989731_1	530564.Psta_1537	1.779e-62	226.0	COG0657@1|root,COG0657@2|Bacteria,2IXCK@203682|Planctomycetes	203682|Planctomycetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,EF-hand_5,Peptidase_S9
LZS2_k127_2989731_2	588596.U9TYB7	7.76e-31	128.0	COG0790@1|root,KOG1550@2759|Eukaryota,39WUS@33154|Opisthokonta	588596.U9TYB7|-	MOT	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2989731_3	63737.Npun_R5539	8.553e-27	125.0	COG0457@1|root,COG0457@2|Bacteria,1G0N0@1117|Cyanobacteria,1HQK0@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_2989731_0	862908.BMS_1601	2.045e-112	379.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2MTPZ@213481|Bdellovibrionales,2WITV@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
LZS2_k127_2992708_1	760568.Desku_1207	2.968e-218	689.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,260X7@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS2_k127_2992708_0	1340434.AXVA01000003_gene2366	6.098e-266	829.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,1ZCMM@1386|Bacillus	91061|Bacilli	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
LZS2_k127_2997514_0	111780.Sta7437_3088	6.993e-39	163.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,1G10B@1117|Cyanobacteria,3VJ4K@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
LZS2_k127_2997514_1	316274.Haur_0990	9.435e-14	75.0	COG0515@1|root,COG0515@2|Bacteria,2G5NM@200795|Chloroflexi,3751T@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_3005254_0	574087.Acear_1154	1.413e-106	355.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3WADR@53433|Halanaerobiales	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
LZS2_k127_3005254_1	857087.Metme_4296	8.499e-74	256.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RVZ6@1236|Gammaproteobacteria,1XEWZ@135618|Methylococcales	135618|Methylococcales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
LZS2_k127_3011057_1	411490.ANACAC_00119	0.0003605	50.0	COG3063@1|root,COG3063@2|Bacteria,1UY48@1239|Firmicutes,24AGF@186801|Clostridia	186801|Clostridia	NU	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_3011057_0	1502852.FG94_00045	4.879e-174	580.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,2VIEC@28216|Betaproteobacteria,473SF@75682|Oxalobacteraceae	28216|Betaproteobacteria	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
LZS2_k127_3020234_0	1173263.Syn7502_00592	4.882e-24	113.0	COG4121@1|root,COG4121@2|Bacteria,1G0ZF@1117|Cyanobacteria,1GYQ5@1129|Synechococcus	1117|Cyanobacteria	S	S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_30
LZS2_k127_3020234_1	1121472.AQWN01000009_gene352	4.779e-17	86.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,262K0@186807|Peptococcaceae	186801|Clostridia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
LZS2_k127_3024859_0	744979.R2A130_0627	1.521e-10	70.0	2CK2Q@1|root,303GN@2|Bacteria,1RG44@1224|Proteobacteria,2U8BW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3026275_2	756272.Plabr_0460	2.384e-20	105.0	COG0515@1|root,COG0515@2|Bacteria,2IXXT@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_3026275_0	697282.Mettu_3337	1.224e-77	264.0	COG1573@1|root,COG1573@2|Bacteria,1QJIF@1224|Proteobacteria,1THIQ@1236|Gammaproteobacteria,1XEAT@135618|Methylococcales	135618|Methylococcales	L	uracil-DNA	-	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS2_k127_3026275_1	448385.sce0038	1.444e-47	192.0	COG0393@1|root,COG0515@1|root,COG0393@2|Bacteria,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439IS@68525|delta/epsilon subdivisions,2X4V7@28221|Deltaproteobacteria,2YZNY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_3038972_0	1303518.CCALI_02781	3.307e-72	249.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	tri	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
LZS2_k127_3038972_1	1175306.GWL_07790	6.499e-41	165.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,473YW@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS2_k127_3038972_2	1178537.BA1_11384	1.521e-16	85.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli,1ZB6D@1386|Bacillus	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	acoC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS2_k127_3040781_0	525904.Tter_0422	1.671e-182	582.0	COG0114@1|root,COG0114@2|Bacteria,2NS3X@2323|unclassified Bacteria	2|Bacteria	C	Fumarase C C-terminus	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS2_k127_3040781_1	42256.RradSPS_2004	1.599e-34	138.0	COG4398@1|root,COG4398@2|Bacteria,2I3VH@201174|Actinobacteria,4CQGG@84995|Rubrobacteria	84995|Rubrobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
LZS2_k127_3041544_1	4006.Lus10005258	2.007e-06	60.0	COG0526@1|root,KOG0907@2759|Eukaryota,37VIK@33090|Viridiplantae,3GJVP@35493|Streptophyta,4JQ4F@91835|fabids	35493|Streptophyta	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_3041544_0	1437425.CSEC_0293	2.668e-19	102.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg,dCache_1,dCache_3
LZS2_k127_3042543_1	204669.Acid345_3896	7.29e-32	131.0	COG5429@1|root,COG5429@2|Bacteria,3Y4TV@57723|Acidobacteria,2JJFF@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
LZS2_k127_3042543_0	1131553.JIBI01000039_gene1952	1.171e-128	424.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2VKNE@28216|Betaproteobacteria,372VG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
LZS2_k127_3070801_0	443143.GM18_0952	1.145e-34	149.0	COG0438@1|root,COG0438@2|Bacteria,1MWVX@1224|Proteobacteria,42WEG@68525|delta/epsilon subdivisions,2WWQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
LZS2_k127_3070801_1	1408442.JADE01000005_gene1226	6.517e-13	78.0	COG1083@1|root,COG1083@2|Bacteria,1QACI@1224|Proteobacteria,42RJA@68525|delta/epsilon subdivisions,2YNVW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Cytidylyltransferase	-	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3
LZS2_k127_3073999_5	1160707.AJIK01000001_gene275	0.0002926	46.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,26D2C@186818|Planococcaceae	91061|Bacilli	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
LZS2_k127_3073999_2	667014.Thein_1534	3.364e-54	196.0	COG2110@1|root,COG2110@2|Bacteria,2GHTV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
LZS2_k127_3073999_4	309799.DICTH_1593	4.51e-06	59.0	COG0745@1|root,COG0745@2|Bacteria	309799.DICTH_1593|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3073999_0	247490.KSU1_C0047	3.143e-154	499.0	COG0334@1|root,COG0334@2|Bacteria,2IWWC@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_3073999_1	243233.MCA0142	1.796e-115	382.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,1S1GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
LZS2_k127_3073999_3	1293054.HSACCH_00330	6.624e-18	85.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,3WAJM@53433|Halanaerobiales	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
LZS2_k127_3074786_3	716928.AJQT01000017_gene4667	6.996e-07	60.0	COG0589@1|root,COG0589@2|Bacteria,1RHZG@1224|Proteobacteria,2UBA5@28211|Alphaproteobacteria,4BEBN@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_3074786_0	91464.S7335_5600	2.415e-170	544.0	COG0015@1|root,COG0015@2|Bacteria,1G07M@1117|Cyanobacteria,1GZ9Y@1129|Synechococcus	1117|Cyanobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
LZS2_k127_3074786_1	478741.JAFS01000001_gene1268	4.558e-164	533.0	COG1640@1|root,COG1640@2|Bacteria,46SX0@74201|Verrucomicrobia,37FX7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
LZS2_k127_3074786_2	1121423.JONT01000003_gene1128	1.248e-33	139.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,261UV@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
LZS2_k127_3080912_3	891968.Anamo_1760	3.768e-31	126.0	COG0369@1|root,COG1151@2|Bacteria,3TA79@508458|Synergistetes	508458|Synergistetes	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
LZS2_k127_3080912_1	880073.Calab_2195	2.453e-95	329.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
LZS2_k127_3080912_0	1379698.RBG1_1C00001G0780	5.911e-107	357.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
LZS2_k127_3080912_4	1379698.RBG1_1C00001G0781	9.511e-26	115.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
LZS2_k127_3080912_2	1121447.JONL01000002_gene1736	3.679e-40	160.0	COG1271@1|root,COG1271@2|Bacteria,1R5SQ@1224|Proteobacteria,43BBG@68525|delta/epsilon subdivisions,2X6QP@28221|Deltaproteobacteria,2MH5E@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	oxidase subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3086571_2	1144275.COCOR_06912	1.629e-22	106.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria,2YU9U@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
LZS2_k127_3086571_0	195250.CM001776_gene3731	1.244e-41	162.0	COG0681@1|root,COG0681@2|Bacteria,1G519@1117|Cyanobacteria,1GZMB@1129|Synechococcus	1117|Cyanobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
LZS2_k127_3086571_1	1329516.JPST01000003_gene1025	1.825e-24	107.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,27BBJ@186824|Thermoactinomycetaceae	91061|Bacilli	E	Glycine cleavage system P-protein	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS2_k127_3102770_0	635013.TherJR_0925	4.047e-269	845.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,263XI@186807|Peptococcaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS2_k127_3102770_1	880072.Desac_2807	7.103e-12	75.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,42Q5T@68525|delta/epsilon subdivisions,2WKN4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
LZS2_k127_3107174_1	926554.KI912633_gene4039	1.607e-10	74.0	COG5002@1|root,COG5002@2|Bacteria,1WNHC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_3107174_0	106370.Francci3_2401	8.399e-46	175.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4ETZ6@85013|Frankiales	201174|Actinobacteria	K	response regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_3107801_3	398512.JQKC01000008_gene899	5.109e-12	76.0	COG0457@1|root,COG0457@2|Bacteria,1V4UY@1239|Firmicutes,25B4A@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_7,TPR_8
LZS2_k127_3107801_4	926566.Terro_0096	1.128e-08	66.0	2DKZV@1|root,311J1@2|Bacteria,3Y9ER@57723|Acidobacteria	57723|Acidobacteria	S	LssY C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	LssY_C
LZS2_k127_3107801_0	926561.KB900617_gene2131	1.22e-70	247.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
LZS2_k127_3107801_2	189426.PODO_05230	5.283e-52	192.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,26SCR@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	yqiK	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
LZS2_k127_3107801_1	1173028.ANKO01000250_gene2299	3.731e-66	239.0	COG1408@1|root,COG1408@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS2_k127_3109790_0	1123376.AUIU01000016_gene283	1.624e-13	78.0	COG3391@1|root,COG4249@1|root,COG3391@2|Bacteria,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,Peptidase_C14,WD40
LZS2_k127_3112106_0	314724.BT0359	8.216e-23	111.0	COG0793@1|root,COG0793@2|Bacteria,2J5QD@203691|Spirochaetes	203691|Spirochaetes	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS2_k127_3112106_1	234267.Acid_5927	0.000167	53.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS2_k127_3116989_0	1246474.ANBE01000028_gene1352	1.263e-17	91.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria,4EK3E@85012|Streptosporangiales	201174|Actinobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS2_k127_3117455_1	767434.Fraau_0456	3.407e-15	78.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1X3WP@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS2_k127_3117455_0	197221.22294255	1.822e-15	79.0	COG0762@1|root,COG0762@2|Bacteria,1G95C@1117|Cyanobacteria	1117|Cyanobacteria	S	YGGT family	ycf19	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
LZS2_k127_3119956_1	243164.DET0650	1.888e-27	124.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi,34D9S@301297|Dehalococcoidia	301297|Dehalococcoidia	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
LZS2_k127_3119956_0	82654.Pse7367_2882	1.982e-51	191.0	COG0373@1|root,COG0373@2|Bacteria,1G04R@1117|Cyanobacteria,1H8PY@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS2_k127_3132624_0	530564.Psta_3553	8.479e-211	667.0	COG1232@1|root,COG1232@2|Bacteria,2IYF5@203682|Planctomycetes	203682|Planctomycetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS2_k127_3132624_3	1128421.JAGA01000002_gene336	1.796e-08	67.0	COG1807@1|root,COG1807@2|Bacteria,2NS23@2323|unclassified Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT,PMT_2
LZS2_k127_3132624_1	1123508.JH636446_gene6283	9.573e-71	251.0	COG1657@1|root,COG2006@1|root,COG1657@2|Bacteria,COG2006@2|Bacteria,2IYV1@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_3132624_2	1340493.JNIF01000004_gene802	1.778e-10	72.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3138899_0	316274.Haur_2274	1.507e-82	281.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi,3773X@32061|Chloroflexia	32061|Chloroflexia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_3138899_2	1131462.DCF50_p401	1.469e-43	174.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,264MW@186807|Peptococcaceae	186801|Clostridia	T	Osmosensitive K channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
LZS2_k127_3138899_3	1379858.N508_00031	0.0001612	50.0	COG5330@1|root,COG5330@2|Bacteria	2|Bacteria	K	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF2336,LRV
LZS2_k127_3138899_1	485913.Krac_6537	2.379e-54	204.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	nifL	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	GAF,HATPase_c,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_3141528_0	502025.Hoch_4569	1.336e-63	241.0	COG0515@1|root,COG1413@1|root,COG0515@2|Bacteria,COG1413@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_3141528_1	36630.CADNFIAP00003215	0.0002372	48.0	COG0457@1|root,KOG1840@2759|Eukaryota,38C2F@33154|Opisthokonta,3NYVZ@4751|Fungi,3QJJI@4890|Ascomycota,20AWC@147545|Eurotiomycetes,3S4I8@5042|Eurotiales	4751|Fungi	Z	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,PNP_UDP_1,Patatin,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_3142076_0	580340.Tlie_0552	5.335e-56	211.0	COG0795@1|root,COG0795@2|Bacteria,3TAEU@508458|Synergistetes	508458|Synergistetes	S	Permease, YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
LZS2_k127_3142076_1	1122217.KB899568_gene818	4.701e-43	160.0	COG1137@1|root,COG1137@2|Bacteria,1UJSV@1239|Firmicutes,4H1UQ@909932|Negativicutes	909932|Negativicutes	S	ABC transporter, ATP-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
LZS2_k127_3142076_2	483219.LILAB_03325	3.744e-35	140.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
LZS2_k127_3142076_3	1009370.ALO_15627	0.0003383	53.0	COG1934@1|root,COG1934@2|Bacteria,1UK23@1239|Firmicutes,4H9AP@909932|Negativicutes	909932|Negativicutes	S	PFAM OstA family protein	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
LZS2_k127_3165425_0	1122223.KB890687_gene2974	1.222e-154	502.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
LZS2_k127_3165425_1	709032.Sulku_0548	1.828e-32	130.0	COG3012@1|root,COG3012@2|Bacteria,1Q5V3@1224|Proteobacteria,42UFW@68525|delta/epsilon subdivisions,2YPTX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
LZS2_k127_3174363_0	448385.sce3104	4.897e-05	55.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
LZS2_k127_3203025_0	883081.HMPREF9698_01049	8.1e-27	123.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,27FC6@186828|Carnobacteriaceae	91061|Bacilli	S	AI-2E family transporter	XK27_05220	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS2_k127_3203025_1	102129.Lepto7375DRAFT_7767	1.045e-07	63.0	COG0457@1|root,COG2909@1|root,COG0457@2|Bacteria,COG2909@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_3203148_1	1487953.JMKF01000089_gene5389	6.084e-73	262.0	COG0038@1|root,COG0517@1|root,COG0589@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,COG0589@2|Bacteria,1G17J@1117|Cyanobacteria,1H998@1150|Oscillatoriales	1117|Cyanobacteria	PT	Chloride channel protein EriC	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Usp,Voltage_CLC
LZS2_k127_3203148_0	163908.KB235896_gene3931	8.405e-95	321.0	COG0038@1|root,COG0517@1|root,COG0589@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,COG0589@2|Bacteria,1G17J@1117|Cyanobacteria,1HKHP@1161|Nostocales	1117|Cyanobacteria	PT	PFAM CBS domain	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Usp,Voltage_CLC
LZS2_k127_3205697_1	1183438.GKIL_3778	1.25e-22	101.0	COG0845@1|root,COG0845@2|Bacteria,1FZZ9@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799,ko:K15727	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1,8.A.1.2.1	-	-	HlyD_D23
LZS2_k127_3205697_0	1183438.GKIL_3779	4.143e-242	764.0	COG3696@1|root,COG3696@2|Bacteria,1GE7Y@1117|Cyanobacteria	2|Bacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
LZS2_k127_3207967_0	1121091.AUMP01000002_gene2232	9.16e-76	267.0	COG1413@1|root,COG1413@2|Bacteria,1TRJT@1239|Firmicutes,4HBFD@91061|Bacilli	91061|Bacilli	C	virulence factor	ypgR	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Nfu_N,Virulence_fact
LZS2_k127_3207967_1	497965.Cyan7822_2309	6.65e-45	168.0	COG0745@1|root,COG0745@2|Bacteria,1G027@1117|Cyanobacteria,3KGE5@43988|Cyanothece	1117|Cyanobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Hpt,Response_reg,Trans_reg_C
LZS2_k127_3209497_2	357808.RoseRS_3357	1.615e-07	64.0	COG0745@1|root,COG0745@2|Bacteria,2GBMQ@200795|Chloroflexi,377KX@32061|Chloroflexia	32061|Chloroflexia	KT	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_3209497_1	1183438.GKIL_3045	8.983e-26	124.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K11383	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
LZS2_k127_3209497_0	1348657.M622_19345	7.067e-61	225.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,2VPC3@28216|Betaproteobacteria,2KYYF@206389|Rhodocyclales	206389|Rhodocyclales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3215417_1	1173263.Syn7502_00013	1.394e-83	286.0	COG0601@1|root,COG0601@2|Bacteria,1G23K@1117|Cyanobacteria,1H47A@1129|Synechococcus	1117|Cyanobacteria	P	ABC-type dipeptide oligopeptide nickel transport	-	-	2.4.2.7	ko:K00759,ko:K02033	ko00230,ko01100,ko02024,map00230,map01100,map02024	M00239	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko00002,ko01000,ko02000,ko04147	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_3215417_0	459495.SPLC1_S490640	1.809e-101	344.0	COG1173@1|root,COG1173@2|Bacteria,1G0BC@1117|Cyanobacteria,1H8MT@1150|Oscillatoriales	1117|Cyanobacteria	EP	'ABC-type dipeptide oligopeptide nickel transport	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_3215417_2	1121289.JHVL01000017_gene731	3.928e-40	155.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,25EWN@186801|Clostridia,36USS@31979|Clostridiaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF_2,HAMP,HD,HD_5,Reg_prop,Response_reg,Y_Y_Y
LZS2_k127_3220563_1	1123368.AUIS01000014_gene2317	2.803e-38	158.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,2NE50@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS2_k127_3220563_0	331678.Cphamn1_2101	3.739e-78	276.0	COG3264@1|root,COG3264@2|Bacteria,1FD9A@1090|Chlorobi	1090|Chlorobi	M	PFAM MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_3235709_0	195250.CM001776_gene1192	2.655e-06	61.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H02K@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02486	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_4,PAS_9,PHY
LZS2_k127_3238817_0	1254432.SCE1572_00175	5.926e-56	206.0	COG0393@1|root,COG0515@1|root,COG0393@2|Bacteria,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439IS@68525|delta/epsilon subdivisions,2X4V7@28221|Deltaproteobacteria,2YZNY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_3238817_1	574375.BAGA_10910	1.163e-40	160.0	COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,1ZGCX@1386|Bacillus	91061|Bacilli	L	DNA alkylation repair	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
LZS2_k127_324127_0	1173024.KI912148_gene4502	1.477e-89	304.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
LZS2_k127_324127_2	933262.AXAM01000005_gene2508	3.737e-05	50.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,42NBF@68525|delta/epsilon subdivisions,2WNW9@28221|Deltaproteobacteria,2MHZE@213118|Desulfobacterales	28221|Deltaproteobacteria	N	PFAM SRP54-type protein, GTPase domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
LZS2_k127_324127_1	385682.AFSL01000082_gene1166	3.488e-50	181.0	COG1488@1|root,COG1488@2|Bacteria,4NFQK@976|Bacteroidetes,2FNJH@200643|Bacteroidia,3XJT6@558415|Marinilabiliaceae	976|Bacteroidetes	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
LZS2_k127_3258338_0	1304875.JAFZ01000002_gene383	8.692e-27	121.0	COG2197@1|root,COG2197@2|Bacteria,3T9YJ@508458|Synergistetes	508458|Synergistetes	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_3258338_2	102129.Lepto7375DRAFT_6140	5.222e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1G7IF@1117|Cyanobacteria,1HH3X@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_3258338_1	32057.KB217478_gene6555	3.08e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1GD9N@1117|Cyanobacteria,1HQT4@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_3277279_1	93059.P9211_11291	2.084e-44	164.0	COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria,1MMD1@1212|Prochloraceae	1117|Cyanobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_3277279_0	649747.HMPREF0083_03345	5.297e-48	190.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,26T15@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
LZS2_k127_3291051_3	1157640.AQWO01000026_gene6065	5.65e-09	63.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
LZS2_k127_3291051_2	497964.CfE428DRAFT_3117	1.041e-23	107.0	2EIPW@1|root,33CFC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3828
LZS2_k127_3291051_1	1408303.JNJJ01000059_gene1211	2.246e-27	115.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,4HXIV@91061|Bacilli,1ZRQH@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
LZS2_k127_3291051_0	102125.Xen7305DRAFT_00047650	3.507e-61	219.0	COG1741@1|root,COG1741@2|Bacteria,1G0UH@1117|Cyanobacteria,3VJ25@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
LZS2_k127_3291051_4	439235.Dalk_3428	2.754e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1N5M0@1224|Proteobacteria,42U23@68525|delta/epsilon subdivisions,2WQ2H@28221|Deltaproteobacteria,2MKG5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
LZS2_k127_3299795_0	1268303.RHODMAR_0830	1.482e-54	214.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FU85@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_3302505_0	1034943.BN1094_02069	1.089e-14	87.0	COG2246@1|root,COG2246@2|Bacteria,1QUSS@1224|Proteobacteria,1SBSJ@1236|Gammaproteobacteria,1JG38@118969|Legionellales	118969|Legionellales	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3302505_1	682795.AciX8_2124	1.455e-11	70.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria,2JKR9@204432|Acidobacteriia	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
LZS2_k127_3307576_1	555079.Toce_0770	5.655e-54	203.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia,42F9G@68295|Thermoanaerobacterales	186801|Clostridia	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	lytR	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
LZS2_k127_3307576_0	1292035.H476_3188	6.451e-79	269.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25QSS@186804|Peptostreptococcaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
LZS2_k127_3324974_1	102129.Lepto7375DRAFT_6172	1.551e-11	68.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1H8JK@1150|Oscillatoriales	1117|Cyanobacteria	O	PDZ domain (Also known as DHR or GLGF)	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_3324974_0	1124780.ANNU01000002_gene1571	3.746e-272	855.0	COG2183@1|root,COG2183@2|Bacteria,4NETD@976|Bacteroidetes,47MKQ@768503|Cytophagia	976|Bacteroidetes	K	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
LZS2_k127_3324974_2	189753.AXAS01000032_gene4145	8.204e-08	61.0	2EH3D@1|root,33AVD@2|Bacteria,1QR7N@1224|Proteobacteria,2TUZ2@28211|Alphaproteobacteria,3JXFI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
LZS2_k127_3334966_1	67257.JODR01000023_gene5253	6.947e-33	131.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_3334966_0	203119.Cthe_2171	1.198e-87	310.0	COG1061@1|root,COG1061@2|Bacteria,1TRA8@1239|Firmicutes,2481H@186801|Clostridia,3WNCQ@541000|Ruminococcaceae	186801|Clostridia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
LZS2_k127_335550_3	211165.AJLN01000015_gene2273	5.346e-16	81.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
LZS2_k127_335550_1	1283283.ATXA01000015_gene129	1.185e-57	220.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4EX2B@85013|Frankiales	201174|Actinobacteria	KLT	Serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_335550_0	645991.Sgly_2334	6.077e-59	231.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_335550_2	1201293.AKXQ01000026_gene1507	1.197e-40	156.0	COG2843@1|root,COG2843@2|Bacteria,1RCV8@1224|Proteobacteria,1S7XX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
LZS2_k127_3359729_1	1125863.JAFN01000001_gene1664	0.0002771	51.0	COG0745@1|root,COG0745@2|Bacteria	1125863.JAFN01000001_gene1664|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3359729_0	46234.ANA_C13102	1.75e-27	123.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1GITD@1117|Cyanobacteria,1HRB3@1161|Nostocales	1117|Cyanobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2
LZS2_k127_3361602_0	1183438.GKIL_0853	5.119e-110	379.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1G45B@1117|Cyanobacteria	1117|Cyanobacteria	PT	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
LZS2_k127_3361602_1	714943.Mucpa_0963	9.792e-37	149.0	COG3000@1|root,COG3000@2|Bacteria,4NGQA@976|Bacteroidetes,1J071@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
LZS2_k127_3368583_3	383372.Rcas_0013	5.745e-33	138.0	COG0204@1|root,COG0204@2|Bacteria,2GACB@200795|Chloroflexi,37578@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS2_k127_3368583_2	439235.Dalk_1447	1.084e-67	241.0	COG0204@1|root,COG0204@2|Bacteria,1N01J@1224|Proteobacteria,42UM7@68525|delta/epsilon subdivisions,2WQN9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS2_k127_3368583_4	1348663.KCH_36980	6.891e-22	99.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,2M3D6@2063|Kitasatospora	201174|Actinobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
LZS2_k127_3368583_0	272558.10172648	1.221e-76	261.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli,1ZBDK@1386|Bacillus	91061|Bacilli	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
LZS2_k127_3368583_1	608538.HTH_1356	1.267e-74	261.0	COG1154@1|root,COG1154@2|Bacteria,2G3R7@200783|Aquificae	200783|Aquificae	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
LZS2_k127_3378611_2	1227349.C170_16490	2.473e-24	108.0	COG2310@1|root,COG2310@2|Bacteria,1TRYY@1239|Firmicutes,4HUTE@91061|Bacilli,26T6X@186822|Paenibacillaceae	91061|Bacilli	T	stress, protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3378611_1	1121904.ARBP01000073_gene264	6.173e-26	111.0	COG0784@1|root,COG0784@2|Bacteria,4NSX5@976|Bacteroidetes,47QFR@768503|Cytophagia	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_3378611_0	1089553.Tph_c14230	1.094e-56	209.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_3380717_3	316275.VSAL_I2667	0.0004845	45.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XSK2@135623|Vibrionales	135623|Vibrionales	M	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
LZS2_k127_3380717_0	648996.Theam_0970	2.11e-103	349.0	COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae	200783|Aquificae	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
LZS2_k127_3380717_2	595494.Tola_2509	1.066e-07	62.0	28RCN@1|root,2ZDS1@2|Bacteria,1NGBU@1224|Proteobacteria,1SUS9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1189
LZS2_k127_3380717_1	98439.AJLL01000066_gene1149	4.171e-49	179.0	COG1670@1|root,COG1670@2|Bacteria,1G5HU@1117|Cyanobacteria,1JHTS@1189|Stigonemataceae	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
LZS2_k127_3390033_3	68199.JNZO01000010_gene6340	6.124e-08	64.0	2ECK6@1|root,336IB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3390033_2	1122138.AQUZ01000126_gene6907	2.082e-10	62.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria,4DU8I@85009|Propionibacteriales	201174|Actinobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
LZS2_k127_3390033_0	1088721.NSU_pLA2026	3.891e-84	284.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2TUNY@28211|Alphaproteobacteria,2K3US@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
LZS2_k127_3390033_1	314230.DSM3645_28142	1.715e-25	114.0	COG3316@1|root,COG3316@2|Bacteria,2J4XX@203682|Planctomycetes	203682|Planctomycetes	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
LZS2_k127_3390946_4	1163617.SCD_n00693	2.296e-111	363.0	COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,2VPGJ@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA2	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS2_k127_3390946_3	1173020.Cha6605_6076	6.834e-157	501.0	COG3588@1|root,COG3588@2|Bacteria,1G2BV@1117|Cyanobacteria	1117|Cyanobacteria	G	fructose-bisphosphate aldolase	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
LZS2_k127_3390946_0	1123508.JH636456_gene147	0.0	1444.0	COG3957@1|root,COG3957@2|Bacteria,2IWYJ@203682|Planctomycetes	203682|Planctomycetes	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
LZS2_k127_3390946_2	1210884.HG799468_gene13638	1.808e-183	591.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,2IWUZ@203682|Planctomycetes	203682|Planctomycetes	P	Rhodanese Homology Domain	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
LZS2_k127_3390946_1	240016.ABIZ01000001_gene5379	1.651e-254	797.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	cadA	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
LZS2_k127_340376_0	205914.HS_0289	2.047e-08	56.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,1RMBX@1236|Gammaproteobacteria,1Y734@135625|Pasteurellales	135625|Pasteurellales	U	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	Z012_08095	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
LZS2_k127_3408785_0	309803.CTN_1042	2.924e-45	176.0	COG0568@1|root,COG0568@2|Bacteria,2GBWY@200918|Thermotogae	200918|Thermotogae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_3408785_2	710696.Intca_2503	1.535e-25	115.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4FGAV@85021|Intrasporangiaceae	201174|Actinobacteria	K	Chemotaxis protein CheY	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_3408785_4	402777.KB235898_gene5767	1.341e-05	53.0	COG1413@1|root,COG1413@2|Bacteria,1G6AT@1117|Cyanobacteria,1HEPD@1150|Oscillatoriales	1117|Cyanobacteria	C	Leucine rich repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_3408785_3	1033734.CAET01000035_gene3221	4.39e-12	73.0	COG0537@1|root,COG0537@2|Bacteria,1V5Q0@1239|Firmicutes,4HHB2@91061|Bacilli,1ZGHY@1386|Bacillus	91061|Bacilli	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
LZS2_k127_3408785_1	246197.MXAN_2680	3.909e-43	177.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4346X@68525|delta/epsilon subdivisions,2XA3R@28221|Deltaproteobacteria,2YXWE@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TonB_C
LZS2_k127_3431790_0	518766.Rmar_1348	3.419e-109	368.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_3431790_1	1120960.ATXG01000017_gene1388	1.271e-64	231.0	COG0702@1|root,COG0702@2|Bacteria,2IQ0Z@201174|Actinobacteria,4FM9R@85023|Microbacteriaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Methyltransf_21,NAD_binding_10
LZS2_k127_3431790_2	946362.XP_004989361.1	2.231e-10	72.0	COG0457@1|root,KOG1840@2759|Eukaryota,38C2F@33154|Opisthokonta	33154|Opisthokonta	Z	Nephrocystin-3	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,PNP_UDP_1,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_3436609_1	1265505.ATUG01000001_gene4066	1.205e-56	226.0	COG0421@1|root,COG0421@2|Bacteria,1R09C@1224|Proteobacteria,42YKN@68525|delta/epsilon subdivisions,2X800@28221|Deltaproteobacteria,2MJY9@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3436609_0	313612.L8106_21649	5.973e-101	364.0	COG0419@1|root,COG0419@2|Bacteria,1G26D@1117|Cyanobacteria,1H7Z9@1150|Oscillatoriales	1117|Cyanobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_15,AAA_23,Rad50_zn_hook,SbcCD_C
LZS2_k127_3442313_0	323259.Mhun_1008	9.413e-54	195.0	COG0717@1|root,arCOG04048@2157|Archaea,2XTSH@28890|Euryarchaeota	28890|Euryarchaeota	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13,3.5.4.30	ko:K01494,ko:K09887	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325,R07307	RC00074,RC01825	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
LZS2_k127_3447101_1	485915.Dret_1178	5.3e-25	119.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,42RRN@68525|delta/epsilon subdivisions,2WK5R@28221|Deltaproteobacteria,2MD59@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3447101_0	309799.DICTH_1380	4.696e-120	398.0	COG0162@1|root,COG0162@2|Bacteria	2|Bacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iJN746.PP_0436,iLJ478.TM0478	S4,tRNA-synt_1b
LZS2_k127_3458790_0	1173263.Syn7502_01731	2.539e-99	342.0	COG0661@1|root,COG0661@2|Bacteria,1G0X9@1117|Cyanobacteria,1GYBK@1129|Synechococcus	1117|Cyanobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
LZS2_k127_3459213_1	1122138.AQUZ01000042_gene3375	0.0009135	49.0	COG3903@1|root,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
LZS2_k127_3459213_0	1144275.COCOR_02951	1.884e-66	246.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
LZS2_k127_3485268_4	497964.CfE428DRAFT_1031	0.0001661	52.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3485268_2	107636.JQNK01000008_gene4059	3.431e-24	104.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2U9NV@28211|Alphaproteobacteria,36YSF@31993|Methylocystaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
LZS2_k127_3485268_1	977880.pRALTA_0652	6.122e-31	126.0	COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,2VTAR@28216|Betaproteobacteria,1K78C@119060|Burkholderiaceae	28216|Betaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS2_k127_3485268_3	536232.CLM_3041	3.139e-16	84.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,24QQ8@186801|Clostridia,36N1D@31979|Clostridiaceae	186801|Clostridia	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
LZS2_k127_3485268_0	1385935.N836_08470	1.518e-44	170.0	COG2094@1|root,COG2094@2|Bacteria,1G55G@1117|Cyanobacteria,1HATN@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the DNA glycosylase MPG family	mpg	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
LZS2_k127_3490977_1	1033734.CAET01000039_gene310	4.461e-06	59.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,4HB4Z@91061|Bacilli,1ZE87@1386|Bacillus	91061|Bacilli	S	virion core protein (lumpy skin disease virus)	ydjI	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zf-ribbon_3
LZS2_k127_3490977_0	1120985.AUMI01000011_gene541	1.616e-28	122.0	COG3271@1|root,COG3271@2|Bacteria,1VAKE@1239|Firmicutes,4H81P@909932|Negativicutes	909932|Negativicutes	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3531318_0	1121938.AUDY01000008_gene1518	8.146e-48	192.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3NEHT@45667|Halobacillus	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_3538956_2	42565.FP66_05830	1.005e-05	49.0	COG0745@1|root,COG0745@2|Bacteria,1RB68@1224|Proteobacteria,1SYBZ@1236|Gammaproteobacteria,1XRJ7@135619|Oceanospirillales	135619|Oceanospirillales	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_3538956_0	246197.MXAN_3202	2.074e-52	208.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
LZS2_k127_3538956_1	1541065.JRFE01000016_gene563	3.291e-26	115.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1G1Y4@1117|Cyanobacteria,3VID8@52604|Pleurocapsales	1117|Cyanobacteria	H	PFAM Tetrapyrrole (Corrin Porphyrin) Methylases	hemD	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.hemD	HEM4,TP_methylase
LZS2_k127_3541253_0	491915.Aflv_2736	9.61e-66	233.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,21V2D@150247|Anoxybacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_3541253_1	321327.CYA_0377	1.693e-38	148.0	COG0142@1|root,COG0142@2|Bacteria,1G1H4@1117|Cyanobacteria,1GZHB@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the FPP GGPP synthase family	crtE	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS2_k127_3543629_3	864702.OsccyDRAFT_3392	7.38e-07	58.0	COG0711@1|root,COG0711@2|Bacteria,1G6NG@1117|Cyanobacteria,1HAPJ@1150|Oscillatoriales	1117|Cyanobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
LZS2_k127_3543629_4	283165.BQ03150	3.133e-06	55.0	COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria,48SY3@772|Bartonellaceae	28211|Alphaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF2	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
LZS2_k127_3543629_2	1183438.GKIL_2235	1.136e-08	61.0	COG0636@1|root,COG0636@2|Bacteria,1G7UT@1117|Cyanobacteria	1117|Cyanobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
LZS2_k127_3543629_0	1183438.GKIL_2236	6.646e-29	125.0	COG0356@1|root,COG0356@2|Bacteria,1G01X@1117|Cyanobacteria	1117|Cyanobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
LZS2_k127_3543629_1	272134.KB731324_gene4431	6.14e-26	112.0	COG1842@1|root,COG1842@2|Bacteria,1G0JY@1117|Cyanobacteria,1H9T3@1150|Oscillatoriales	1117|Cyanobacteria	KT	Phage shock protein A (IM30) suppresses sigma54-dependent transcription	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
LZS2_k127_3546833_0	313612.L8106_12960	7.254e-124	407.0	COG0451@1|root,COG0451@2|Bacteria,1G3T6@1117|Cyanobacteria,1HA43@1150|Oscillatoriales	1117|Cyanobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS2_k127_3546833_1	1530186.JQEY01000001_gene768	1.589e-107	365.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,2U3T3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
LZS2_k127_3546833_2	324602.Caur_0535	3.236e-05	55.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,374YY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_3552942_2	1124780.ANNU01000005_gene2530	2.715e-50	185.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,47K5N@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
LZS2_k127_3552942_4	1268072.PSAB_20965	1.553e-24	115.0	COG0330@1|root,COG0330@2|Bacteria,1UZJK@1239|Firmicutes,4HGVU@91061|Bacilli,26RE7@186822|Paenibacillaceae	91061|Bacilli	O	HflC protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_3552942_5	1410617.JHXH01000009_gene1698	1.427e-15	88.0	COG0330@1|root,COG0330@2|Bacteria,1UZJK@1239|Firmicutes,24IK1@186801|Clostridia,3WHEQ@541000|Ruminococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_3552942_3	195250.CM001776_gene3871	9.457e-50	194.0	COG0793@1|root,COG0793@2|Bacteria,1G1YJ@1117|Cyanobacteria,1GYEZ@1129|Synechococcus	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
LZS2_k127_3552942_1	644966.Tmar_1718	5.356e-84	290.0	COG1028@1|root,COG1028@2|Bacteria,1TR53@1239|Firmicutes,247XS@186801|Clostridia	186801|Clostridia	IQ	Dehydrogenase	ydaD	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS2_k127_3552942_0	204669.Acid345_1443	1.116e-116	394.0	COG1012@1|root,COG1012@2|Bacteria,3Y6J2@57723|Acidobacteria,2JMD6@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
LZS2_k127_3552942_6	521096.Tpau_4188	4.8e-06	58.0	COG3662@1|root,COG3662@2|Bacteria,2GMUA@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
LZS2_k127_3565939_1	65393.PCC7424_2709	5.056e-28	115.0	COG0225@1|root,COG0225@2|Bacteria,1G52T@1117|Cyanobacteria,3KHVH@43988|Cyanothece	1117|Cyanobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
LZS2_k127_3565939_0	748449.Halha_0046	6.522e-86	309.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WAIF@53433|Halanaerobiales	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
LZS2_k127_3575772_0	1445613.JALM01000099_gene4515	8.227e-55	211.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DZBG@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_3590063_1	395961.Cyan7425_4679	3.829e-77	269.0	COG1566@1|root,COG1566@2|Bacteria,1G19K@1117|Cyanobacteria,3KK7Q@43988|Cyanothece	1117|Cyanobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993,ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS2_k127_3590063_0	306281.AJLK01000189_gene1794	8.768e-95	319.0	COG1131@1|root,COG1131@2|Bacteria,1G0RY@1117|Cyanobacteria,1JJUE@1189|Stigonemataceae	1117|Cyanobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS2_k127_3609821_0	102125.Xen7305DRAFT_00034750	5.735e-41	169.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,1G10B@1117|Cyanobacteria,3VJ4K@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
LZS2_k127_3616577_0	1121422.AUMW01000010_gene1041	8.928e-28	121.0	COG4195@1|root,COG4195@2|Bacteria,1VBQ5@1239|Firmicutes,24S3I@186801|Clostridia	186801|Clostridia	S	Poly-gamma-glutamate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Gamma_PGA_hydro
LZS2_k127_3622485_0	883067.HMPREF9237_00446	6.73e-20	100.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4D3B2@85005|Actinomycetales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_3622485_1	1173024.KI912148_gene2957	2.487e-11	76.0	COG0457@1|root,COG3206@1|root,COG0457@2|Bacteria,COG3206@2|Bacteria,1G1U5@1117|Cyanobacteria,1JHI2@1189|Stigonemataceae	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_362305_1	1249480.B649_05875	2.434e-118	403.0	COG0745@1|root,COG2206@1|root,COG0745@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42QQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
LZS2_k127_362305_3	1123242.JH636436_gene751	5.329e-06	52.0	COG1544@1|root,COG1544@2|Bacteria,2J0UN@203682|Planctomycetes	203682|Planctomycetes	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
LZS2_k127_362305_0	522306.CAP2UW1_1124	1.124e-124	405.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,2VJKF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
LZS2_k127_3623539_0	1128421.JAGA01000003_gene3499	2.051e-24	118.0	COG1705@1|root,COG1705@2|Bacteria	2|Bacteria	NU	amidase activity	-	-	3.5.1.28	ko:K01448,ko:K02395	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02035,ko03036	-	-	-	Amidase_3,CHAP,CW_binding_1,GBS_Bsp-like,Glucosaminidase,Glyco_hydro_25
LZS2_k127_3623539_2	32057.KB217478_gene2797	1.159e-18	102.0	COG0797@1|root,COG0797@2|Bacteria,1G0XF@1117|Cyanobacteria,1HKDW@1161|Nostocales	1117|Cyanobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
LZS2_k127_3623539_1	1460635.JCM19038_924	4.56e-21	109.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli	91061|Bacilli	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,SH3_3,SLH
LZS2_k127_3623539_3	278963.ATWD01000001_gene2368	3.133e-05	51.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria,2JIUC@204432|Acidobacteriia	204432|Acidobacteriia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	-	-	-	-	-	-	-	-	-	IMS
LZS2_k127_3623624_1	1128421.JAGA01000002_gene1027	1.098e-14	87.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
LZS2_k127_3623624_0	682795.AciX8_2535	5.998e-55	201.0	COG3010@1|root,COG3010@2|Bacteria,3Y7QX@57723|Acidobacteria,2JMXN@204432|Acidobacteriia	204432|Acidobacteriia	G	Putative N-acetylmannosamine-6-phosphate epimerase	-	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE,ROK
LZS2_k127_3629843_0	1117108.PAALTS15_19163	1.003e-53	201.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,26THY@186822|Paenibacillaceae	91061|Bacilli	E	amino acid	yfnA	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS2_k127_3630505_0	574375.BAGA_23095	7.86e-45	168.0	COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,4HAA2@91061|Bacilli,1ZD9Q@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ybfP	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
LZS2_k127_3630505_1	395961.Cyan7425_2717	3.374e-44	165.0	COG3328@1|root,COG3328@2|Bacteria,1G3YG@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
LZS2_k127_3631135_3	313624.NSP_48850	1.022e-13	84.0	COG1538@1|root,COG1538@2|Bacteria,1G0B8@1117|Cyanobacteria,1HJB4@1161|Nostocales	1117|Cyanobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K03287	-	-	-	-	ko00000	1.B.17	-	-	OEP
LZS2_k127_3631135_1	517417.Cpar_0512	1.072e-40	156.0	COG1335@1|root,COG1335@2|Bacteria,1FE0F@1090|Chlorobi	1090|Chlorobi	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
LZS2_k127_3631135_0	1121373.KB903663_gene1049	3.946e-69	248.0	COG0535@1|root,COG0535@2|Bacteria,4NJ4D@976|Bacteroidetes,47K2Y@768503|Cytophagia	976|Bacteroidetes	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS2_k127_3631135_2	1217703.F904_03338	1.692e-25	109.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,3NJPR@468|Moraxellaceae	1236|Gammaproteobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
LZS2_k127_3633498_2	1356854.N007_20095	6.446e-05	47.0	2DMH3@1|root,32RGP@2|Bacteria,1VN64@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3633498_0	69279.BG36_04770	4.96e-61	217.0	COG1961@1|root,COG1961@2|Bacteria,1PE0Q@1224|Proteobacteria,2V7D8@28211|Alphaproteobacteria,43QBH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
LZS2_k127_3633498_3	1123024.AUII01000023_gene262	0.0001341	45.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
LZS2_k127_3633498_1	260799.BAS1812	3.671e-07	62.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1TP24@1239|Firmicutes,4HA77@91061|Bacilli,1ZCHY@1386|Bacillus	91061|Bacilli	M	COG1388 FOG LysM repeat	-	-	-	ko:K19223,ko:K19224	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,PG_binding_1,SH3_3
LZS2_k127_3635397_4	485914.Hmuk_2353	4.509e-15	76.0	COG1247@1|root,arCOG00830@2157|Archaea,2XXA1@28890|Euryarchaeota,23VUW@183963|Halobacteria	183963|Halobacteria	K	COG1247 Sortase and related acyltransferases	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
LZS2_k127_3635397_8	1410632.JHWW01000001_gene1092	0.0005567	52.0	COG3063@1|root,COG3063@2|Bacteria,1UY48@1239|Firmicutes,24AGF@186801|Clostridia,27JDX@186928|unclassified Lachnospiraceae	186801|Clostridia	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_3635397_5	1122963.AUHB01000004_gene3113	1.102e-05	57.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2UDVJ@28211|Alphaproteobacteria,371DV@31993|Methylocystaceae	28211|Alphaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
LZS2_k127_3635397_7	1224746.B932_0491	0.0001817	53.0	COG3577@1|root,COG3577@2|Bacteria,1N45S@1224|Proteobacteria,2UGU4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,gag-asp_proteas
LZS2_k127_3635397_2	546275.FUSPEROL_00561	8.41e-47	177.0	COG0463@1|root,COG0463@2|Bacteria,378GA@32066|Fusobacteria	32066|Fusobacteria	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
LZS2_k127_3635397_6	43989.cce_1720	0.0001534	54.0	COG3577@1|root,COG3577@2|Bacteria,1G81F@1117|Cyanobacteria,3KHTG@43988|Cyanothece	1117|Cyanobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	Asp_protease_2,gag-asp_proteas
LZS2_k127_3635397_1	1227457.C451_18498	2.301e-63	233.0	COG1960@1|root,arCOG01707@2157|Archaea,2XT5S@28890|Euryarchaeota,23SK3@183963|Halobacteria	183963|Halobacteria	I	COG1960 Acyl-CoA dehydrogenases	acdG	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_3635397_3	216432.CA2559_01205	3.121e-42	158.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1I1X5@117743|Flavobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
LZS2_k127_3635397_0	485913.Krac_8783	7.298e-103	346.0	COG0404@1|root,COG0404@2|Bacteria,2G5VA@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
LZS2_k127_3641593_2	398527.Bphyt_4058	0.0007844	42.0	COG2020@1|root,COG2020@2|Bacteria,1R55E@1224|Proteobacteria,2VWQW@28216|Betaproteobacteria,1K3XD@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
LZS2_k127_3641593_1	1249627.D779_1989	2.401e-18	90.0	COG2041@1|root,COG2041@2|Bacteria,1RKA7@1224|Proteobacteria,1S7VH@1236|Gammaproteobacteria,1WYTH@135613|Chromatiales	135613|Chromatiales	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
LZS2_k127_3641593_0	452637.Oter_0981	3.49e-155	502.0	COG2070@1|root,COG2070@2|Bacteria,46UTY@74201|Verrucomicrobia,3K79P@414999|Opitutae	414999|Opitutae	C	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
LZS2_k127_365170_0	1267534.KB906756_gene411	9.417e-134	436.0	COG3185@1|root,COG3185@2|Bacteria,3Y2ST@57723|Acidobacteria,2JISR@204432|Acidobacteriia	204432|Acidobacteriia	E	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase
LZS2_k127_365170_2	1297742.A176_06888	4.066e-61	237.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4346X@68525|delta/epsilon subdivisions,2XA3R@28221|Deltaproteobacteria,2YXWE@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TonB_C
LZS2_k127_365170_1	1267535.KB906767_gene5520	5.417e-116	384.0	COG0079@1|root,COG0079@2|Bacteria,3Y4H9@57723|Acidobacteria,2JMT4@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_3657516_1	1121405.dsmv_2802	8.171e-10	62.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2MJ7T@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
LZS2_k127_3657516_0	1172190.M947_03340	1.351e-127	431.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2YMMU@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_3658572_0	1120936.KB907211_gene109	1.373e-39	166.0	COG4886@1|root,COG4886@2|Bacteria,2GNZ0@201174|Actinobacteria,4EI25@85012|Streptosporangiales	201174|Actinobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3658572_3	512565.AMIS_45990	1.465e-18	89.0	2B4Q9@1|root,31XGJ@2|Bacteria,2IKKF@201174|Actinobacteria,4DFR5@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3658572_4	1148.1653502	7.892e-15	88.0	COG0457@1|root,COG0457@2|Bacteria	1148.1653502|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3658572_1	349521.HCH_06118	3.228e-35	153.0	2EC04@1|root,335ZE@2|Bacteria,1NA1N@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1266
LZS2_k127_3658572_2	1347368.HG964404_gene5160	4.521e-24	109.0	COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,4HAA2@91061|Bacilli,1ZD9Q@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ybfP	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
LZS2_k127_3658572_5	585502.HMPREF0645_0691	0.0007376	51.0	COG0542@1|root,COG0542@2|Bacteria,4NE1J@976|Bacteroidetes,2FNNW@200643|Bacteroidia	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_3682796_0	595536.ADVE02000001_gene2418	1.772e-73	250.0	COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,2U5FW@28211|Alphaproteobacteria,36Y9U@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1348)	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
LZS2_k127_3682796_2	208444.JNYY01000020_gene4624	5.985e-13	74.0	COG0607@1|root,COG0607@2|Bacteria,2IIWA@201174|Actinobacteria,4E52W@85010|Pseudonocardiales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding,Rhodanese
LZS2_k127_3682796_1	1294265.JCM21738_54	3.569e-22	112.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus	91061|Bacilli	T	Histidine kinase	resE	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
LZS2_k127_3686748_1	211165.AJLN01000088_gene2608	1.192e-26	119.0	COG0745@1|root,COG0745@2|Bacteria,1G51F@1117|Cyanobacteria,1JJDJ@1189|Stigonemataceae	1117|Cyanobacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
LZS2_k127_3686748_0	1267535.KB906767_gene5339	1.39e-82	293.0	COG3437@1|root,COG4251@1|root,COG3437@2|Bacteria,COG4251@2|Bacteria,3Y4QP@57723|Acidobacteria,2JP3I@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_3696016_0	332101.JIBU02000084_gene4192	6.876e-21	105.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,36FCZ@31979|Clostridiaceae	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
LZS2_k127_3711515_0	1144275.COCOR_07949	1.282e-112	384.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43C8M@68525|delta/epsilon subdivisions,2X7J0@28221|Deltaproteobacteria,2YXZD@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
LZS2_k127_3715605_0	1499967.BAYZ01000153_gene1545	1.883e-18	99.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_3724180_0	1336235.JAEG01000001_gene2377	1.427e-48	188.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2UP3F@28211|Alphaproteobacteria,4B8BG@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Nicotinamidase	pncA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043094,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
LZS2_k127_3724180_1	1536774.H70357_25570	1.017e-38	159.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,4IJJ3@91061|Bacilli,26RP0@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
LZS2_k127_3724180_2	1313301.AUGC01000016_gene845	2.886e-09	62.0	COG0462@1|root,COG0462@2|Bacteria,4NGB3@976|Bacteroidetes	976|Bacteroidetes	EF	Ribose-phosphate pyrophosphokinase	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
LZS2_k127_3742663_0	1487953.JMKF01000002_gene518	2.502e-27	127.0	COG2204@1|root,COG5002@1|root,COG2204@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,HisKA_3,PAS,PAS_4,PAS_9,Response_reg
LZS2_k127_3742663_1	269797.Mbar_A3036	2.975e-24	112.0	COG2203@1|root,arCOG02348@1|root,arCOG02348@2157|Archaea,arCOG02361@2157|Archaea,2Y7N6@28890|Euryarchaeota,2NBKD@224756|Methanomicrobia	224756|Methanomicrobia	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS_9
LZS2_k127_3747110_0	886293.Sinac_3408	3.409e-98	354.0	COG2304@1|root,COG2304@2|Bacteria,2J2CJ@203682|Planctomycetes	203682|Planctomycetes	NU	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
LZS2_k127_3752986_0	264732.Moth_0266	1.011e-177	566.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,42ER3@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
LZS2_k127_3756601_0	1122169.AREN01000009_gene549	7.554e-59	213.0	COG0664@1|root,COG0664@2|Bacteria,1QU34@1224|Proteobacteria,1T2BY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
LZS2_k127_3756601_2	1507.HMPREF0262_01853	2.428e-24	114.0	COG1752@1|root,COG1752@2|Bacteria,1UBYN@1239|Firmicutes,247V3@186801|Clostridia,36WRU@31979|Clostridiaceae	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS2_k127_3756601_1	1469607.KK073768_gene379	3.653e-29	122.0	COG0426@1|root,COG1853@1|root,COG0426@2|Bacteria,COG1853@2|Bacteria,1G0DJ@1117|Cyanobacteria,1HITV@1161|Nostocales	1117|Cyanobacteria	C	Flavin reductase like domain	dfa3	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_1,Lactamase_B
LZS2_k127_37591_0	316067.Geob_2105	1.959e-69	251.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria,43TBC@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
LZS2_k127_37591_1	330214.NIDE3032	7.108e-34	136.0	COG1663@1|root,COG1663@2|Bacteria,3J0QN@40117|Nitrospirae	40117|Nitrospirae	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
LZS2_k127_3772376_0	234267.Acid_1972	9.53e-299	944.0	COG1028@1|root,COG2070@1|root,COG3266@1|root,COG3321@1|root,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3266@2|Bacteria,COG3321@2|Bacteria,3Y347@57723|Acidobacteria	57723|Acidobacteria	Q	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
LZS2_k127_3774060_2	439292.Bsel_1549	1.308e-28	118.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,26NJP@186821|Sporolactobacillaceae	91061|Bacilli	E	Oligopeptidase F	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
LZS2_k127_3774060_1	986075.CathTA2_1894	2.819e-48	195.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_3774060_0	861299.J421_0495	5.255e-54	200.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
LZS2_k127_3776990_0	555778.Hneap_2107	7.47e-44	175.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RP75@1236|Gammaproteobacteria,1WWJF@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,RHS_repeat
LZS2_k127_3780432_1	1104324.P186_1188	2.59e-35	149.0	COG2986@1|root,arCOG04671@2157|Archaea,2XRW8@28889|Crenarchaeota	28889|Crenarchaeota	E	Aromatic amino acid lyase	-	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
LZS2_k127_3780432_2	1298593.TOL_1719	4.303e-09	67.0	COG2010@1|root,COG2010@2|Bacteria,1RFJV@1224|Proteobacteria,1S4GY@1236|Gammaproteobacteria,1XPKF@135619|Oceanospirillales	135619|Oceanospirillales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS2_k127_3780432_0	1124780.ANNU01000013_gene3800	1.3e-98	338.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes,47JZ0@768503|Cytophagia	976|Bacteroidetes	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
LZS2_k127_3790210_1	1121289.JHVL01000018_gene581	2.298e-29	134.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,36EE8@31979|Clostridiaceae	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD-helicase,UvrD_C
LZS2_k127_3790210_0	1329516.JPST01000019_gene2733	1.541e-29	128.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,27CSD@186824|Thermoactinomycetaceae	91061|Bacilli	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS2_k127_3800122_0	1128421.JAGA01000003_gene2905	7.866e-110	373.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
LZS2_k127_3800122_1	56107.Cylst_2244	7.76e-31	128.0	COG5190@1|root,COG5190@2|Bacteria,1G5PJ@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM NLI interacting	-	-	-	-	-	-	-	-	-	-	-	-	NIF
LZS2_k127_3812907_0	478741.JAFS01000002_gene87	2.491e-05	56.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
LZS2_k127_3825129_0	234831.PSM_B0229	1.942e-05	56.0	2F01F@1|root,33T59@2|Bacteria,1NQJY@1224|Proteobacteria,1SMIU@1236|Gammaproteobacteria,2Q40U@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
LZS2_k127_382969_0	502025.Hoch_2051	1.152e-114	380.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2WKJ4@28221|Deltaproteobacteria,2YUPH@29|Myxococcales	28221|Deltaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
LZS2_k127_382969_1	502025.Hoch_2048	2.031e-69	243.0	COG0121@1|root,COG1305@1|root,COG0121@2|Bacteria,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,42PJK@68525|delta/epsilon subdivisions,2WMCS@28221|Deltaproteobacteria,2YU92@29|Myxococcales	28221|Deltaproteobacteria	E	Bacterial transglutaminase-like N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,GATase_4,Transglut_core
LZS2_k127_3838049_0	2903.EOD04064	2.91e-74	265.0	2CZ38@1|root,2S860@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
LZS2_k127_3838049_3	5786.XP_003294248.1	1.371e-50	190.0	COG0494@1|root,KOG3041@2759|Eukaryota,3XC9J@554915|Amoebozoa	554915|Amoebozoa	L	NUDIX domain	-	-	3.6.1.21	ko:K18447	ko00051,ko00230,ko00500,ko01100,ko01110,map00051,map00230,map00500,map01100,map01110	-	R00951,R01885,R02677	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
LZS2_k127_3838049_1	243265.plu2614	5.651e-69	244.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,1RPGI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS2_k127_3838049_2	858215.Thexy_0238	8.186e-59	215.0	COG4638@1|root,COG4638@2|Bacteria,1UYZZ@1239|Firmicutes,248NK@186801|Clostridia	186801|Clostridia	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rieske
LZS2_k127_3838049_4	314230.DSM3645_09827	1.265e-16	91.0	2ER32@1|root,33INP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4259
LZS2_k127_3845436_4	237368.SCABRO_02564	4.569e-45	173.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2IZEZ@203682|Planctomycetes	203682|Planctomycetes	S	Memo-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1,Memo
LZS2_k127_3845436_5	1173027.Mic7113_2714	2.003e-07	59.0	COG0501@1|root,COG4105@1|root,COG0501@2|Bacteria,COG4105@2|Bacteria,1G16J@1117|Cyanobacteria,1H9Q8@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
LZS2_k127_3845436_1	926550.CLDAP_28040	3.173e-115	387.0	COG0174@1|root,COG0174@2|Bacteria,2G62E@200795|Chloroflexi	200795|Chloroflexi	E	Glutamine synthetase N-terminal domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N_2
LZS2_k127_3845436_3	526227.Mesil_3285	2.432e-46	181.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS2_k127_3845436_0	240015.ACP_0329	5.675e-136	441.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
LZS2_k127_3845436_2	240015.ACP_0328	3.098e-108	355.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
LZS2_k127_384604_0	768704.Desmer_1795	0.0001812	47.0	COG1846@1|root,COG1846@2|Bacteria,1VBQ9@1239|Firmicutes,24P4Y@186801|Clostridia,262VI@186807|Peptococcaceae	186801|Clostridia	K	PFAM MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
LZS2_k127_3867004_0	383372.Rcas_2968	2.282e-89	301.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
LZS2_k127_3867004_1	862908.BMS_1056	4.852e-29	119.0	COG1874@1|root,COG1874@2|Bacteria,1R8CV@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolase family 14	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_14
LZS2_k127_3874434_2	314607.KB13_87	1.076e-07	59.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,1KQEI@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
LZS2_k127_3874434_1	351348.Maqu_2436	2.743e-12	72.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,468UE@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
LZS2_k127_3874434_0	1121422.AUMW01000016_gene2035	1.012e-26	117.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,26287@186807|Peptococcaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
LZS2_k127_3879493_0	5911.EAR95020	1.439e-18	100.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_3885735_0	886293.Sinac_7521	1.246e-58	215.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Pur_ac_phosph_N,SLH
LZS2_k127_3885735_1	349124.Hhal_0404	3.93e-25	109.0	COG3449@1|root,COG3449@2|Bacteria,1RF2U@1224|Proteobacteria,1S2JU@1236|Gammaproteobacteria,1WXYM@135613|Chromatiales	135613|Chromatiales	L	PFAM SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
LZS2_k127_3890521_0	935837.JAEK01000057_gene2468	2.074e-40	158.0	COG2801@1|root,COG2801@2|Bacteria,1TSH4@1239|Firmicutes,4HDYB@91061|Bacilli,1ZR3Q@1386|Bacillus	91061|Bacilli	L	Mu transposase, C-terminal	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,Mu-transpos_C,rve
LZS2_k127_3890521_1	985867.AEWF01000011_gene1249	3.092e-34	134.0	COG1961@1|root,COG1961@2|Bacteria,1RBKN@1224|Proteobacteria,2U6XS@28211|Alphaproteobacteria,47G4F@766|Rickettsiales	766|Rickettsiales	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
LZS2_k127_3890521_2	244582.JQAK01000002_gene550	1.447e-22	99.0	COG1961@1|root,COG1961@2|Bacteria,1RBKN@1224|Proteobacteria,2U6XS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_7,Resolvase
LZS2_k127_3890521_3	1296415.JACC01000006_gene1518	1.498e-14	84.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia,2YKRI@290174|Aquimarina	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_3890521_4	42345.XP_008797807.1	1.179e-07	63.0	COG0589@1|root,2RZF9@2759|Eukaryota,37V17@33090|Viridiplantae,3GISS@35493|Streptophyta,3M009@4447|Liliopsida	35493|Streptophyta	T	Universal stress protein A-like protein	-	GO:0000166,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016208,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_3899307_1	767817.Desgi_4020	1.517e-82	288.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3	ko:K00074,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N
LZS2_k127_3899307_0	439235.Dalk_3029	0.0	1099.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WM1R@28221|Deltaproteobacteria,2MID5@213118|Desulfobacterales	28221|Deltaproteobacteria	KL	SNF2 Helicase protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
LZS2_k127_3899307_2	439235.Dalk_3030	1.933e-82	286.0	COG2944@1|root,COG4279@1|root,COG2944@2|Bacteria,COG4279@2|Bacteria,1N5C3@1224|Proteobacteria,42QFI@68525|delta/epsilon subdivisions,2WKF8@28221|Deltaproteobacteria,2MIDB@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM zinc finger SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
LZS2_k127_3899307_3	545694.TREPR_2623	6.163e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,2J5NB@203691|Spirochaetes	203691|Spirochaetes	S	tetratricopeptide repeat	lmp1	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
LZS2_k127_3909517_2	1218103.CIN01S_12_01280	7.46e-21	94.0	COG3220@1|root,COG3220@2|Bacteria,4NJE1@976|Bacteroidetes,1I1TI@117743|Flavobacteriia,3ZPJJ@59732|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF692)	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
LZS2_k127_3909517_4	41431.PCC8801_0906	2.709e-09	64.0	COG0438@1|root,COG1215@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,1FZUY@1117|Cyanobacteria	1117|Cyanobacteria	M	glycosyl transferase group 1	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_31,Sulfotransfer_3
LZS2_k127_3909517_0	497964.CfE428DRAFT_3430	7.283e-68	243.0	COG3975@1|root,COG3975@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	Peptidase_M61
LZS2_k127_3909517_1	502025.Hoch_0362	1.028e-59	228.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,4389R@68525|delta/epsilon subdivisions,2XA3N@28221|Deltaproteobacteria,2YWAI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
LZS2_k127_3909863_0	258052.JNYV01000002_gene1261	1.619e-31	139.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,2M17I@2063|Kitasatospora	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_3910588_0	690850.Desaf_3383	4.144e-118	387.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,42T4X@68525|delta/epsilon subdivisions,2WPCA@28221|Deltaproteobacteria,2MCJP@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
LZS2_k127_3917182_1	543632.JOJL01000047_gene3341	2.045e-06	58.0	COG0457@1|root,COG0457@2|Bacteria	543632.JOJL01000047_gene3341|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3917182_2	1121895.Q765_03580	3.689e-05	53.0	2F3U6@1|root,33WKF@2|Bacteria,4P3HF@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3917182_0	1192034.CAP_3826	7.011e-22	107.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WNGS@28221|Deltaproteobacteria,2YVXN@29|Myxococcales	28221|Deltaproteobacteria	S	of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
LZS2_k127_3917182_3	553178.CAPGI0001_2517	0.0007362	51.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia,1EQ2Q@1016|Capnocytophaga	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
LZS2_k127_3921302_0	1128427.KB904821_gene1776	3.067e-10	70.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_3925022_0	1449976.KALB_2854	1.514e-41	167.0	COG1457@1|root,COG1457@2|Bacteria	2|Bacteria	F	cytosine transport	-	-	-	ko:K10974	-	-	-	-	ko00000,ko02000	2.A.39.1	-	-	Transp_cyt_pur
LZS2_k127_3925022_1	868864.Dester_1041	0.0008696	50.0	COG3063@1|root,COG3063@2|Bacteria,2G4AU@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_2,TPR_6,TPR_8
LZS2_k127_3925359_0	323097.Nham_3434	3.933e-76	259.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JQNW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
LZS2_k127_3925359_1	756499.Desde_3597	2.71e-50	194.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,261KX@186807|Peptococcaceae	186801|Clostridia	E	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_3931891_1	1463917.JODC01000004_gene6174	6.693e-07	60.0	COG1670@1|root,COG1670@2|Bacteria,2IGHV@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
LZS2_k127_3931891_0	1173025.GEI7407_3189	1.392e-67	234.0	COG0110@1|root,COG0110@2|Bacteria,1G58Y@1117|Cyanobacteria,1HAM6@1150|Oscillatoriales	1117|Cyanobacteria	S	Acetyltransferase (Isoleucine patch superfamily)	maa	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
LZS2_k127_3934942_0	1379698.RBG1_1C00001G1879	4.902e-102	343.0	COG1154@1|root,COG1154@2|Bacteria,2NNNA@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	iEcSMS35_1347.EcSMS35_0456,iJN746.PP_0527	DXP_synthase_N,Transket_pyr,Transketolase_C
LZS2_k127_3937273_2	439235.Dalk_0815	5.513e-29	118.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QXM@68525|delta/epsilon subdivisions,2WMZI@28221|Deltaproteobacteria,2MNC9@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS2_k127_3937273_0	868864.Dester_1304	3.161e-103	344.0	COG0115@1|root,COG0115@2|Bacteria,2G3W3@200783|Aquificae	200783|Aquificae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS2_k127_3937273_3	1487953.JMKF01000086_gene5547	3.682e-06	55.0	COG0457@1|root,COG0457@2|Bacteria,1G1G9@1117|Cyanobacteria,1H889@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_3937273_1	204669.Acid345_2162	8.074e-70	250.0	COG1462@1|root,COG1462@2|Bacteria,3Y3KF@57723|Acidobacteria	57723|Acidobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
LZS2_k127_3939809_6	1266925.JHVX01000011_gene1484	1.204e-08	68.0	COG0457@1|root,COG0457@2|Bacteria,1MWRF@1224|Proteobacteria,2VVW1@28216|Betaproteobacteria,372SV@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_7
LZS2_k127_3939809_3	1254432.SCE1572_11150	1.638e-52	195.0	COG0451@1|root,COG0451@2|Bacteria,1QY1S@1224|Proteobacteria,42X11@68525|delta/epsilon subdivisions,2WKDA@28221|Deltaproteobacteria,2YVD6@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS2_k127_3939809_1	292459.STH1199	1.83e-61	222.0	COG3694@1|root,COG3694@2|Bacteria,1V1MN@1239|Firmicutes,24EE6@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
LZS2_k127_3939809_2	555079.Toce_1739	1.403e-59	215.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,2599A@186801|Clostridia,42H86@68295|Thermoanaerobacterales	186801|Clostridia	S	transport system permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
LZS2_k127_3939809_0	1157490.EL26_23240	3.534e-112	371.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4HEB4@91061|Bacilli,27950@186823|Alicyclobacillaceae	91061|Bacilli	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_3939809_4	118168.MC7420_7631	2.249e-18	98.0	COG0457@1|root,COG0457@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Pentapeptide,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_3939809_5	1173024.KI912149_gene5610	5.343e-13	76.0	COG1216@1|root,COG1216@2|Bacteria,1G2E9@1117|Cyanobacteria,1JK0P@1189|Stigonemataceae	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_3945332_1	1499689.CCNN01000007_gene1218	5.184e-77	267.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,247KZ@186801|Clostridia,36FJV@31979|Clostridiaceae	186801|Clostridia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
LZS2_k127_3945332_0	1382358.JHVN01000013_gene1800	2.434e-171	550.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,4H9N0@91061|Bacilli	91061|Bacilli	F	COG0044 Dihydroorotase and related cyclic amidohydrolases	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
LZS2_k127_3959400_1	56107.Cylst_0108	5.53e-31	136.0	COG0212@1|root,COG0212@2|Bacteria,1G2B2@1117|Cyanobacteria,1HKTF@1161|Nostocales	1117|Cyanobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3959400_0	1278073.MYSTI_00456	1.464e-36	156.0	2E458@1|root,32Z1A@2|Bacteria,1PAGT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3959400_2	1499967.BAYZ01000181_gene4505	9.886e-20	101.0	COG4585@1|root,COG5002@1|root,COG4585@2|Bacteria,COG5002@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HAMP,HATPase_c,HisKA_3,PAS,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
LZS2_k127_3960550_1	693661.Arcve_1516	3.801e-06	60.0	COG5549@1|root,arCOG04994@2157|Archaea,2XZZ9@28890|Euryarchaeota	28890|Euryarchaeota	O	Matrixin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
LZS2_k127_3960550_0	391600.ABRU01000025_gene1078	1.99e-44	164.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2U2PN@28211|Alphaproteobacteria,2KHKV@204458|Caulobacterales	204458|Caulobacterales	S	RTCB protein	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
LZS2_k127_3966092_0	1122963.AUHB01000017_gene1985	3.394e-32	126.0	COG2944@1|root,COG2944@2|Bacteria,1N05Y@1224|Proteobacteria,2UCCG@28211|Alphaproteobacteria,36YU9@31993|Methylocystaceae	28211|Alphaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
LZS2_k127_3966092_1	177437.HRM2_03840	1.649e-18	90.0	COG1061@1|root,COG1502@1|root,COG4951@1|root,COG1061@2|Bacteria,COG1502@2|Bacteria,COG4951@2|Bacteria,1QWMJ@1224|Proteobacteria,42NXF@68525|delta/epsilon subdivisions,2WJWA@28221|Deltaproteobacteria,2MJ9J@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
LZS2_k127_3966401_1	1121920.AUAU01000023_gene2419	5.609e-68	239.0	COG2086@1|root,COG2086@2|Bacteria,3Y2PD@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
LZS2_k127_3966401_0	1230341.MJ3_04184	5.796e-84	289.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli	91061|Bacilli	C	Electron transfer flavoprotein	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
LZS2_k127_3966401_2	65093.PCC7418_1762	6.665e-37	143.0	COG0073@1|root,COG0073@2|Bacteria,1G78D@1117|Cyanobacteria	1117|Cyanobacteria	J	TIGRFAM methionyl-tRNA synthetase C-terminal region beta chain	-	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
LZS2_k127_3966401_3	1122221.JHVI01000003_gene317	1.626e-07	53.0	COG0821@1|root,COG0821@2|Bacteria,1WJ94@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
LZS2_k127_3970300_4	760192.Halhy_5302	4.33e-10	63.0	COG0145@1|root,COG0145@2|Bacteria,4NFBV@976|Bacteroidetes	976|Bacteroidetes	EQ	Hydantoinase/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
LZS2_k127_3970300_2	1173028.ANKO01000215_gene6262	7.244e-19	91.0	COG1547@1|root,COG1547@2|Bacteria,1G7QG@1117|Cyanobacteria,1HBGH@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
LZS2_k127_3970300_0	1121468.AUBR01000022_gene2771	3.676e-36	149.0	COG2199@1|root,COG3706@2|Bacteria,1VADD@1239|Firmicutes,25E7Q@186801|Clostridia,42J5P@68295|Thermoanaerobacterales	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_9,Response_reg,TPR_8
LZS2_k127_3970300_1	398512.JQKC01000007_gene1020	1.531e-32	134.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3WIM6@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
LZS2_k127_3970300_3	272134.KB731324_gene1213	5.753e-18	92.0	2DZVH@1|root,32VK2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
LZS2_k127_3973338_1	1121342.AUCO01000015_gene2700	2.823e-36	148.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,36GKC@31979|Clostridiaceae	186801|Clostridia	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
LZS2_k127_3973338_0	221288.JH992901_gene5694	1.017e-120	398.0	COG2255@1|root,COG2255@2|Bacteria,1G1CN@1117|Cyanobacteria,1JHZ3@1189|Stigonemataceae	1117|Cyanobacteria	L	Holliday junction DNA helicase ruvB C-terminus	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
LZS2_k127_397394_0	536227.CcarbDRAFT_2839	1.335e-31	138.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,36WU1@31979|Clostridiaceae	186801|Clostridia	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_3983365_0	485918.Cpin_5356	2.937e-05	57.0	2DBPJ@1|root,2ZA9D@2|Bacteria,4NJYC@976|Bacteroidetes,1IQIQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
LZS2_k127_3987446_0	1515613.HQ37_08395	1.643e-09	70.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,2FM0Y@200643|Bacteroidia,22WU4@171551|Porphyromonadaceae	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
LZS2_k127_3990079_0	251221.35210753	3.453e-83	282.0	COG2876@1|root,COG2876@2|Bacteria,1G205@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM DAHP synthetase I	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS2_k127_39912_2	756272.Plabr_3034	1.078e-14	78.0	COG0591@1|root,COG0591@2|Bacteria,2J22E@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS2_k127_39912_0	56110.Oscil6304_2245	3.866e-200	633.0	COG0017@1|root,COG0017@2|Bacteria,1G015@1117|Cyanobacteria,1H7PZ@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS2_k127_39912_1	1131269.AQVV01000019_gene782	1.43e-72	251.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	yrrM	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
LZS2_k127_4001824_0	1123400.KB904802_gene3159	9.443e-48	191.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,1RNRY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2
LZS2_k127_4003558_1	215803.DB30_5360	2.879e-22	104.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4003558_0	643867.Ftrac_2833	1.03e-167	531.0	COG2159@1|root,COG2159@2|Bacteria,4NIGJ@976|Bacteroidetes,47KJH@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
LZS2_k127_4003558_3	1173263.Syn7502_03431	0.0001321	54.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1H1V5@1129|Synechococcus	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,PNP_UDP_1,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_4003558_2	344747.PM8797T_25626	4.832e-10	72.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,2IX13@203682|Planctomycetes	2|Bacteria	N	Protein of unknown function (DUF1549)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
LZS2_k127_4005534_0	991905.SL003B_2152	1.564e-39	154.0	COG1309@1|root,COG1309@2|Bacteria,1QYD4@1224|Proteobacteria,2TVBJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator, TetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
LZS2_k127_4005534_1	1121938.AUDY01000008_gene1518	5.075e-35	139.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3NEHT@45667|Halobacillus	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_4015038_0	1347392.CCEZ01000019_gene1055	5.126e-81	291.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,36F3M@31979|Clostridiaceae	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
LZS2_k127_4015038_1	861299.J421_0084	3.359e-05	51.0	COG0204@1|root,COG0204@2|Bacteria,1ZSY9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS2_k127_4027020_1	234267.Acid_1973	1.75e-28	132.0	COG2091@1|root,COG3321@1|root,COG2091@2|Bacteria,COG3321@2|Bacteria,3Y347@57723|Acidobacteria	57723|Acidobacteria	Q	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
LZS2_k127_4027020_0	402881.Plav_3311	2.386e-56	204.0	COG0110@1|root,COG0110@2|Bacteria,1RAKB@1224|Proteobacteria,2U3JX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
LZS2_k127_4027020_2	1454007.JAUG01000036_gene4379	2.895e-18	91.0	COG5285@1|root,COG5285@2|Bacteria,4NFFH@976|Bacteroidetes	976|Bacteroidetes	Q	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS2_k127_4029196_1	1349767.GJA_3476	0.0001093	52.0	COG0457@1|root,COG1192@1|root,COG0457@2|Bacteria,COG1192@2|Bacteria,1PWCI@1224|Proteobacteria,2WBXA@28216|Betaproteobacteria,476N2@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12
LZS2_k127_4029196_0	1297617.JPJD01000012_gene845	5.977e-14	74.0	COG3757@1|root,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,2692E@186813|unclassified Clostridiales	186801|Clostridia	M	Glycosyl hydrolases family 25	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,LysM
LZS2_k127_4033093_0	686340.Metal_2212	1.069e-127	422.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XG6A@135618|Methylococcales	135618|Methylococcales	C	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Haem_bd
LZS2_k127_4033093_3	83219.PM02_08265	9.942e-05	49.0	2E4QM@1|root,32ZJ7@2|Bacteria,1NEXN@1224|Proteobacteria,2UJMP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4033093_1	1005994.GTGU_02978	1.573e-27	114.0	COG4589@1|root,COG4589@2|Bacteria,1MX58@1224|Proteobacteria,1RRAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphatidate cytidylyltransferase	ynbB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
LZS2_k127_4033093_2	1124991.MU9_1834	5.33e-10	66.0	COG4589@1|root,COG4589@2|Bacteria,1MX58@1224|Proteobacteria,1RRAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphatidate cytidylyltransferase	ynbB	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
LZS2_k127_4033093_4	526222.Desal_3201	0.00041	49.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2M91R@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
LZS2_k127_4033101_0	1173022.Cri9333_3015	7.223e-147	478.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H8GB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	glsF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
LZS2_k127_4042738_1	479431.Namu_3381	2.405e-20	91.0	COG3360@1|root,COG3360@2|Bacteria,2IQ6Z@201174|Actinobacteria,4ETCR@85013|Frankiales	201174|Actinobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
LZS2_k127_4042738_0	591001.Acfer_0427	3.859e-61	217.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H37X@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
LZS2_k127_4042738_2	1128398.Curi_c15650	1.523e-12	69.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,267TD@186813|unclassified Clostridiales	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
LZS2_k127_4045384_0	1167006.UWK_00109	6.38e-28	118.0	COG0123@1|root,COG0454@1|root,COG0123@2|Bacteria,COG0456@2|Bacteria,1MU7P@1224|Proteobacteria,42NAQ@68525|delta/epsilon subdivisions,2WJPX@28221|Deltaproteobacteria,2MK5E@213118|Desulfobacterales	28221|Deltaproteobacteria	BKQ	Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Hist_deacetyl
LZS2_k127_405564_1	748727.CLJU_c00020	4.272e-51	196.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,36E0C@31979|Clostridiaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
LZS2_k127_405564_0	865861.AZSU01000006_gene1168	4.712e-128	424.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,36DSQ@31979|Clostridiaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS2_k127_405564_4	439235.Dalk_4136	0.0001351	46.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,42WSU@68525|delta/epsilon subdivisions,2WSI8@28221|Deltaproteobacteria,2MM9N@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
LZS2_k127_405564_3	1173025.GEI7407_3403	3.208e-07	58.0	COG0594@1|root,COG0594@2|Bacteria,1G7Z7@1117|Cyanobacteria,1HC5M@1150|Oscillatoriales	1117|Cyanobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
LZS2_k127_405564_2	580340.Tlie_0711	4.181e-18	87.0	COG0759@1|root,COG0759@2|Bacteria,3TBI4@508458|Synergistetes	508458|Synergistetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
LZS2_k127_4065693_0	886293.Sinac_1862	8.547e-53	191.0	COG2234@1|root,COG2234@2|Bacteria,2IWTP@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS2_k127_4069465_1	517418.Ctha_1145	1.292e-15	89.0	COG4782@1|root,COG4782@2|Bacteria,1FDWU@1090|Chlorobi	1090|Chlorobi	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
LZS2_k127_4069465_0	1487953.JMKF01000091_gene5292	2.148e-111	384.0	COG0475@1|root,COG0569@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,COG1226@2|Bacteria,1G014@1117|Cyanobacteria,1H97H@1150|Oscillatoriales	1117|Cyanobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
LZS2_k127_4069465_2	202955.BBND01000017_gene1551	2.943e-10	73.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,3NM5D@468|Moraxellaceae	1236|Gammaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
LZS2_k127_4070484_4	555779.Dthio_PD3134	4.346e-07	54.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2M8H0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS2_k127_4070484_1	272134.KB731324_gene3382	2.79e-26	113.0	COG1430@1|root,COG1430@2|Bacteria,1G6N9@1117|Cyanobacteria,1HBR4@1150|Oscillatoriales	1117|Cyanobacteria	S	acr, cog1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
LZS2_k127_4070484_0	235985.BBPN01000053_gene7895	8.526e-35	143.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria,2NG46@228398|Streptacidiphilus	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS2_k127_4070484_2	562970.Btus_1081	1.007e-22	101.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,278KT@186823|Alicyclobacillaceae	91061|Bacilli	O	NifU-like domain	yutI	-	-	-	-	-	-	-	-	-	-	-	NifU
LZS2_k127_4070484_3	634504.Bgr_18520	2.612e-13	71.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TR6E@28211|Alphaproteobacteria,48T5J@772|Bartonellaceae	28211|Alphaproteobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
LZS2_k127_4077742_0	1356852.N008_15640	5.811e-18	97.0	COG1397@1|root,COG1397@2|Bacteria,4P1DN@976|Bacteroidetes,47T8F@768503|Cytophagia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4079709_1	153721.MYP_1542	1.035e-32	129.0	COG4262@1|root,COG4262@2|Bacteria,4NFVH@976|Bacteroidetes,47NJJ@768503|Cytophagia	976|Bacteroidetes	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
LZS2_k127_4079709_0	497964.CfE428DRAFT_5205	1.337e-147	485.0	COG1231@1|root,COG1231@2|Bacteria	2|Bacteria	E	oxidoreductase activity	-	-	1.5.99.6	ko:K00316	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R01914,R01915	RC00053,RC00225	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
LZS2_k127_4079709_2	1185876.BN8_01142	1.066e-14	76.0	28M67@1|root,2ZAJW@2|Bacteria,4NF2D@976|Bacteroidetes,47N18@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4079994_0	1007103.AFHW01000021_gene209	2.762e-13	79.0	COG1011@1|root,COG1011@2|Bacteria,1TRP5@1239|Firmicutes,4HBSP@91061|Bacilli,26QYS@186822|Paenibacillaceae	91061|Bacilli	S	hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_4082787_2	1267535.KB906767_gene2200	2.288e-60	211.0	COG0473@1|root,COG0473@2|Bacteria,3Y3BC@57723|Acidobacteria,2JKC7@204432|Acidobacteriia	204432|Acidobacteriia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS2_k127_4082787_0	930166.CD58_01595	1.605e-99	353.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1RYEF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	bphP	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY,Response_reg
LZS2_k127_4082787_1	1242864.D187_006689	8.024e-69	245.0	COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
LZS2_k127_4082787_3	649638.Trad_0258	1.943e-21	105.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48
LZS2_k127_4082860_0	65393.PCC7424_2512	1.149e-95	332.0	COG0654@1|root,COG1225@1|root,COG0654@2|Bacteria,COG1225@2|Bacteria,1G5VZ@1117|Cyanobacteria,3KJ59@43988|Cyanothece	1117|Cyanobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS2_k127_4092336_3	1303518.CCALI_01936	1.644e-41	160.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
LZS2_k127_4092336_1	1303518.CCALI_01936	2.202e-47	175.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
LZS2_k127_4092336_2	1173025.GEI7407_0435	4.141e-42	166.0	COG2177@1|root,COG2177@2|Bacteria,1G2PZ@1117|Cyanobacteria,1H6YT@1150|Oscillatoriales	1117|Cyanobacteria	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
LZS2_k127_4092336_0	1120971.AUCA01000007_gene2164	1.267e-79	271.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli,277XT@186823|Alicyclobacillaceae	91061|Bacilli	D	ABC transporter	ftsE	GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
LZS2_k127_4092336_4	457570.Nther_0005	0.0009022	49.0	COG5512@1|root,COG5512@2|Bacteria,1V9FF@1239|Firmicutes,24XCD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
LZS2_k127_4092636_1	1510531.JQJJ01000015_gene3055	6.977e-14	73.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2TUCW@28211|Alphaproteobacteria,3K6EA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_4092636_0	91464.S7335_1587	7.482e-42	162.0	2C7F0@1|root,2Z832@2|Bacteria,1FZVC@1117|Cyanobacteria,1H060@1129|Synechococcus	1117|Cyanobacteria	S	PFAM HAS barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	HAS-barrel
LZS2_k127_4100970_2	1297581.H919_09753	9.257e-16	81.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,21WWI@150247|Anoxybacillus	91061|Bacilli	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08510	CoaE
LZS2_k127_4100970_1	1121403.AUCV01000046_gene1118	8.696e-18	98.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asp_protease_2,PDZ,PDZ_2,Peptidase_M28,Peptidase_S55
LZS2_k127_4100970_0	269084.syc0399_d	2.269e-66	236.0	COG0283@1|root,COG0414@1|root,COG0283@2|Bacteria,COG0414@2|Bacteria,1G1BX@1117|Cyanobacteria,1GZ7F@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC/cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25,6.3.2.1	ko:K13799	ko00240,ko00410,ko00770,ko01100,ko01110,map00240,map00410,map00770,map01100,map01110	M00052,M00119	R00158,R00512,R01665,R02473	RC00002,RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,Pantoate_ligase
LZS2_k127_4102450_0	264462.Bd0254	3.486e-92	324.0	COG0322@1|root,COG0847@1|root,COG0322@2|Bacteria,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342,ko:K03703,ko:K04096	ko00230,ko00240,ko01100,ko03030,ko03420,ko03430,ko03440,map00230,map00240,map01100,map03030,map03420,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DUF4357,GIY-YIG,RNase_T
LZS2_k127_4102450_1	3694.POPTR_0014s05720.1	3.912e-05	54.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37PZP@33090|Viridiplantae,3GFZZ@35493|Streptophyta,4JFX1@91835|fabids	35493|Streptophyta	O	Belongs to the peptidase M10A family	-	-	-	ko:K07999	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
LZS2_k127_4108301_1	1144275.COCOR_07948	1.921e-110	377.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2X7CV@28221|Deltaproteobacteria,2YUZ7@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
LZS2_k127_4108301_4	526227.Mesil_1660	5.896e-06	56.0	COG0457@1|root,COG0457@2|Bacteria,1WIGW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_4108301_2	330214.NIDE3501	1.337e-44	183.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
LZS2_k127_4108301_0	1238182.C882_4345	8.16e-179	580.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,2TXK8@28211|Alphaproteobacteria,2JVHU@204441|Rhodospirillales	204441|Rhodospirillales	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS2_k127_4108301_3	340177.Cag_1169	2.135e-08	63.0	COG0457@1|root,COG0457@2|Bacteria,1FD7Y@1090|Chlorobi	1090|Chlorobi	K	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TIR_2,TPR_12,TPR_7
LZS2_k127_41107_1	1123399.AQVE01000001_gene500	8.34e-59	217.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,460EH@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
LZS2_k127_41107_0	1242864.D187_010069	1.919e-62	241.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
LZS2_k127_41107_4	572544.Ilyop_2934	3.599e-06	55.0	COG0457@1|root,COG0457@2|Bacteria	572544.Ilyop_2934|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_41107_2	1111134.HMPREF1253_1471	3.026e-08	59.0	COG1716@1|root,COG1716@2|Bacteria,1VF0E@1239|Firmicutes,24JR7@186801|Clostridia,22JFV@1570339|Peptoniphilaceae	186801|Clostridia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
LZS2_k127_41107_3	485913.Krac_8182	4.583e-07	63.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
LZS2_k127_4121588_1	479436.Vpar_0522	6.342e-50	187.0	COG0767@1|root,COG0767@2|Bacteria,1U95A@1239|Firmicutes,4H2EU@909932|Negativicutes	909932|Negativicutes	Q	Belongs to the MlaE permease family	mlaE	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
LZS2_k127_4121588_0	880073.Calab_2702	6.872e-57	207.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
LZS2_k127_4121588_2	1189619.pgond44_06055	4.805e-16	89.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia,4C2G8@83612|Psychroflexus	976|Bacteroidetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
LZS2_k127_4123374_1	251229.Chro_1915	2.333e-20	96.0	COG2193@1|root,COG2193@2|Bacteria,1G50V@1117|Cyanobacteria,3VJY1@52604|Pleurocapsales	1117|Cyanobacteria	P	Bacterioferritin (cytochrome b1)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
LZS2_k127_4123374_0	1301100.HG529236_gene7281	1.506e-41	171.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,36GGI@31979|Clostridiaceae	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
LZS2_k127_4132259_0	926569.ANT_28720	2.595e-80	274.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_4132259_2	1029824.AFID01000002_gene1396	4.04e-08	66.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,1W90S@1268|Micrococcaceae	201174|Actinobacteria	O	Tetratricopeptide repeat	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
LZS2_k127_4132259_3	638303.Thal_1064	4.205e-05	56.0	COG0457@1|root,COG1729@1|root,COG3063@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG3063@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_4132259_1	234267.Acid_4430	4.142e-16	91.0	COG0457@1|root,COG0726@1|root,COG4249@1|root,COG0457@2|Bacteria,COG0726@2|Bacteria,COG4249@2|Bacteria,3Y77C@57723|Acidobacteria	57723|Acidobacteria	G	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Polysacc_deac_1,TPR_2,WD40
LZS2_k127_4136555_0	204669.Acid345_3503	1.33e-52	199.0	COG2203@1|root,COG5000@1|root,COG5002@1|root,COG5278@1|root,COG2203@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,3Y2HT@57723|Acidobacteria,2JIGE@204432|Acidobacteriia	204432|Acidobacteriia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS2_k127_4144320_3	671143.DAMO_1646	8.11e-15	79.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
LZS2_k127_4144320_1	330214.NIDE3036	4.827e-138	459.0	COG1132@1|root,COG1132@2|Bacteria,3J0X8@40117|Nitrospirae	40117|Nitrospirae	V	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_4144320_0	471223.GWCH70_1836	4.034e-244	762.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,4HBK9@91061|Bacilli,1WEPJ@129337|Geobacillus	91061|Bacilli	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	iYO844.BSU18210	Carboxyl_trans
LZS2_k127_4144320_2	743836.AYNA01000067_gene489	4.791e-53	206.0	COG1233@1|root,COG1233@2|Bacteria,1N849@1224|Proteobacteria,2TX2W@28211|Alphaproteobacteria,371FQ@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
LZS2_k127_4144320_4	68570.DC74_5705	3.357e-11	74.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria	201174|Actinobacteria	T	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
LZS2_k127_4144320_5	627192.SLG_06780	3.554e-05	49.0	2EHT0@1|root,33BIQ@2|Bacteria,1NI2F@1224|Proteobacteria,2UMCN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_415182_3	1226994.AMZB01000109_gene1751	8.658e-08	59.0	28I5Z@1|root,2Z893@2|Bacteria,1PMFX@1224|Proteobacteria,1SPT3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
LZS2_k127_415182_1	215803.DB30_6572	7.382e-54	217.0	COG2304@1|root,COG2304@2|Bacteria,1MX4C@1224|Proteobacteria,439DU@68525|delta/epsilon subdivisions,2X4NR@28221|Deltaproteobacteria,2YZBD@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
LZS2_k127_415182_0	316274.Haur_1478	2.198e-78	269.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,375BD@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_415182_2	596152.DesU5LDRAFT_1959	5.864e-09	62.0	2AHGR@1|root,317U5@2|Bacteria,1PZ82@1224|Proteobacteria,435T2@68525|delta/epsilon subdivisions,2X083@28221|Deltaproteobacteria,2MB5N@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_415245_0	321332.CYB_2755	8.158e-92	308.0	COG0825@1|root,COG0825@2|Bacteria,1G0PY@1117|Cyanobacteria,1GYBB@1129|Synechococcus	1117|Cyanobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accA	ACCA
LZS2_k127_415245_1	1254432.SCE1572_22030	2.526e-67	250.0	COG0515@1|root,COG0745@1|root,COG3266@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG3266@2|Bacteria,1NVZF@1224|Proteobacteria,42ZUK@68525|delta/epsilon subdivisions,2X7NR@28221|Deltaproteobacteria,2Z3H7@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,Response_reg
LZS2_k127_4175528_0	118173.KB235914_gene2113	6.313e-130	429.0	COG0621@1|root,COG0621@2|Bacteria,1G07B@1117|Cyanobacteria,1H7W6@1150|Oscillatoriales	1117|Cyanobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
LZS2_k127_4175528_1	1089553.Tph_c11520	7.719e-05	51.0	COG1426@1|root,COG1426@2|Bacteria,1V1N7@1239|Firmicutes,24M2Q@186801|Clostridia,42J4X@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
LZS2_k127_419732_1	324925.Ppha_0446	2.453e-23	110.0	COG0457@1|root,COG0457@2|Bacteria,1FD7Y@1090|Chlorobi	1090|Chlorobi	K	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
LZS2_k127_419732_0	1122947.FR7_3647	1.279e-106	372.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H360@909932|Negativicutes	909932|Negativicutes	M	Penicillin-binding Protein	pbpD	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
LZS2_k127_4211987_0	391612.CY0110_26298	7.11e-13	72.0	COG0338@1|root,COG0338@2|Bacteria,1G2H8@1117|Cyanobacteria,3KHAX@43988|Cyanothece	1117|Cyanobacteria	H	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
LZS2_k127_4233194_0	675635.Psed_0723	0.0001941	51.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,4E0B2@85010|Pseudonocardiales	201174|Actinobacteria	F	nucleoside hydrolase	rihA	-	-	ko:K01250	-	-	-	-	ko00000,ko01000	-	-	-	IU_nuc_hydro
LZS2_k127_4238560_1	243274.THEMA_03065	2.727e-41	162.0	COG0461@1|root,COG0461@2|Bacteria,2GD2M@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS2_k127_4238560_0	1123008.KB905697_gene3300	4.396e-45	172.0	COG2071@1|root,COG2071@2|Bacteria,4PM5S@976|Bacteroidetes,2G0PJ@200643|Bacteroidia,2326P@171551|Porphyromonadaceae	976|Bacteroidetes	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
LZS2_k127_4238560_2	3067.XP_002953694.1	7.614e-27	121.0	COG0330@1|root,KOG3090@2759|Eukaryota,37MNX@33090|Viridiplantae,34H39@3041|Chlorophyta	3041|Chlorophyta	O	prohibitin homologues	-	-	-	ko:K17081	-	-	-	-	ko00000,ko03029,ko04147	-	-	-	Band_7
LZS2_k127_4239450_0	1123368.AUIS01000018_gene723	2.808e-287	906.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	methionine synthase	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS2_k127_4245406_0	159087.Daro_0925	2.432e-21	109.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,2KUR5@206389|Rhodocyclales	206389|Rhodocyclales	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
LZS2_k127_4246922_0	338963.Pcar_1253	6.487e-56	206.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,43SEC@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
LZS2_k127_4246922_2	1122947.FR7_1557	1.606e-05	54.0	COG2825@1|root,COG2825@2|Bacteria,1V8QT@1239|Firmicutes,4H4RJ@909932|Negativicutes	909932|Negativicutes	M	outer membrane chaperone Skp (OmpH)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
LZS2_k127_4246922_1	574087.Acear_2201	4.915e-36	154.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,24F0X@186801|Clostridia,3WAA6@53433|Halanaerobiales	186801|Clostridia	M	PFAM Surface antigen variable number repeat	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS2_k127_4261189_3	1408442.JADE01000006_gene252	4.01e-31	124.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2YMWB@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Biotin carboxylase	pycA	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS2_k127_4261189_1	1382304.JNIL01000001_gene2312	9.082e-83	284.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,279C1@186823|Alicyclobacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
LZS2_k127_4261189_2	331678.Cphamn1_2222	3.617e-57	214.0	COG1215@1|root,COG1215@2|Bacteria,1FDR6@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_4261189_4	489825.LYNGBM3L_64400	0.000946	44.0	COG1923@1|root,COG1923@2|Bacteria,1G93Q@1117|Cyanobacteria,1HCTP@1150|Oscillatoriales	1117|Cyanobacteria	S	regulation of RNA biosynthetic process	-	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
LZS2_k127_4261189_0	1487953.JMKF01000088_gene5419	1.311e-113	375.0	COG1077@1|root,COG1077@2|Bacteria,1G26R@1117|Cyanobacteria,1H80K@1150|Oscillatoriales	1117|Cyanobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
LZS2_k127_4273481_3	1452718.JBOY01000010_gene3205	1.795e-10	66.0	COG1544@1|root,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
LZS2_k127_4273481_5	28072.Nos7524_4965	3.042e-08	66.0	COG5549@1|root,COG5549@2|Bacteria,1G4CD@1117|Cyanobacteria,1HK64@1161|Nostocales	1117|Cyanobacteria	O	SMART Peptidase, metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
LZS2_k127_4273481_2	56110.Oscil6304_0361	2.031e-13	82.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_4273481_1	864702.OsccyDRAFT_1396	3.716e-15	78.0	COG2501@1|root,COG2501@2|Bacteria,1G9E2@1117|Cyanobacteria,1HDRD@1150|Oscillatoriales	1117|Cyanobacteria	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
LZS2_k127_4273481_4	546271.Selsp_0935	2.504e-10	70.0	2962C@1|root,2ZCIE@2|Bacteria,1V1UZ@1239|Firmicutes,4H44C@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2939
LZS2_k127_4273481_0	526222.Desal_0728	1.868e-149	480.0	COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,43DT5@68525|delta/epsilon subdivisions,2X2RT@28221|Deltaproteobacteria,2M7Z4@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
LZS2_k127_4279051_1	575788.VS_1643	2.448e-31	141.0	COG0210@1|root,COG0210@2|Bacteria,1MWW6@1224|Proteobacteria,1RYRU@1236|Gammaproteobacteria,1XUXW@135623|Vibrionales	135623|Vibrionales	L	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,NERD,UvrD_C
LZS2_k127_4279051_0	1173025.GEI7407_1095	1.59e-50	181.0	COG0338@1|root,COG0338@2|Bacteria,1G0BF@1117|Cyanobacteria,1H9B8@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
LZS2_k127_430696_0	926550.CLDAP_00560	7.245e-07	62.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
LZS2_k127_4319187_1	1267535.KB906767_gene5472	1.564e-38	146.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_4319187_0	103690.17131813	2.215e-78	275.0	COG0438@1|root,COG0438@2|Bacteria,1G0TD@1117|Cyanobacteria,1HMQE@1161|Nostocales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	ko:K03867	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_434209_2	313612.L8106_00720	2.428e-77	274.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_434209_1	523791.Kkor_1773	2.373e-119	398.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1XIB1@135619|Oceanospirillales	135619|Oceanospirillales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
LZS2_k127_434209_0	28072.Nos7524_4239	1.036e-145	472.0	COG0436@1|root,COG0436@2|Bacteria,1G2TF@1117|Cyanobacteria,1HJDX@1161|Nostocales	1117|Cyanobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_4348921_3	32057.KB217478_gene3852	3.699e-39	163.0	COG0750@1|root,COG0750@2|Bacteria,1G1WM@1117|Cyanobacteria,1HJRJ@1161|Nostocales	1117|Cyanobacteria	M	zinc metalloprotease	rseP	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M50
LZS2_k127_4348921_2	102129.Lepto7375DRAFT_4432	3.411e-61	233.0	COG2385@1|root,COG2385@2|Bacteria,1G2FP@1117|Cyanobacteria,1H8UJ@1150|Oscillatoriales	1117|Cyanobacteria	D	PFAM Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
LZS2_k127_4348921_1	395961.Cyan7425_1493	1.521e-71	251.0	COG0224@1|root,COG0224@2|Bacteria,1G0G4@1117|Cyanobacteria,3KG4K@43988|Cyanothece	1117|Cyanobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpC	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
LZS2_k127_4348921_0	498761.HM1_1102	1.812e-206	653.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS2_k127_4348921_4	373903.Hore_17830	3.73e-24	108.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,3WATA@53433|Halanaerobiales	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
LZS2_k127_4362586_1	1183438.GKIL_4366	6.22e-10	63.0	COG1842@1|root,COG1842@2|Bacteria,1G1GX@1117|Cyanobacteria	1117|Cyanobacteria	KT	Phage shock protein A (IM30) suppresses sigma54-dependent transcription	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
LZS2_k127_4362586_0	596315.HMPREF0634_0646	1.01e-137	447.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,25QE3@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
LZS2_k127_4362586_2	483219.LILAB_02190	2.226e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1PEH7@1224|Proteobacteria,42TVC@68525|delta/epsilon subdivisions,2WSCX@28221|Deltaproteobacteria,2YXM3@29|Myxococcales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TPR_14,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8
LZS2_k127_4362586_3	1453503.AU05_11830	0.000629	51.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1YEY6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NT	Signal transducing histidine kinase, homodimeric domain	cheA3	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
LZS2_k127_437250_0	102232.GLO73106DRAFT_00008360	3.684e-96	331.0	COG1007@1|root,COG1007@2|Bacteria,1G1FM@1117|Cyanobacteria	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhB	-	1.6.5.3	ko:K05573	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.ndhB	Proton_antipo_M
LZS2_k127_437250_1	745718.JADT01000023_gene1398	4.782e-11	69.0	COG0629@1|root,COG0629@2|Bacteria,4NQBK@976|Bacteroidetes,1I2UG@117743|Flavobacteriia	976|Bacteroidetes	L	single-stranded DNA-binding protein	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS2_k127_4395467_0	1337936.IJ00_23625	7.494e-135	440.0	COG0206@1|root,COG0206@2|Bacteria,1G0AN@1117|Cyanobacteria,1HIWE@1161|Nostocales	1117|Cyanobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000910,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0032153,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS2_k127_4395467_2	868595.Desca_1093	2.942e-95	323.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,260GP@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
LZS2_k127_4395467_3	243159.AFE_0778	2.253e-74	255.0	COG3194@1|root,COG3194@2|Bacteria,1NAR2@1224|Proteobacteria,1SFNH@1236|Gammaproteobacteria,2NCIX@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Ureidoglycolate lyase	-	-	4.3.2.3	ko:K01483	ko00230,ko01100,map00230,map01100	-	R00776	RC00153,RC00379	ko00000,ko00001,ko01000	-	-	-	Ureidogly_lyase
LZS2_k127_4395467_1	1415780.JPOG01000001_gene2632	2.347e-122	402.0	2DBC4@1|root,2Z8BS@2|Bacteria,1PXQW@1224|Proteobacteria,1S38J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret	-	-	3.5.2.15	ko:K03383	ko00791,ko01100,ko01120,map00791,map01100,map01120	-	R05561	RC01423,RC03058	ko00000,ko00001,ko01000	-	-	-	Amido_AtzD_TrzD
LZS2_k127_4395467_5	1458357.BG58_20860	5.438e-23	113.0	COG2267@1|root,COG2267@2|Bacteria,1P7JV@1224|Proteobacteria,2VR0X@28216|Betaproteobacteria,1K7Z4@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
LZS2_k127_4395467_4	266779.Meso_2924	1.702e-48	192.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,43GZZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EH	PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS2_k127_4407454_0	886293.Sinac_3139	9.208e-41	157.0	COG5285@1|root,COG5285@2|Bacteria,2IZRZ@203682|Planctomycetes	203682|Planctomycetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS2_k127_4407454_1	1499967.BAYZ01000095_gene4239	3.284e-13	81.0	COG1100@1|root,COG2319@1|root,COG1100@2|Bacteria,COG2319@2|Bacteria,2NREY@2323|unclassified Bacteria	2|Bacteria	M	Anaphase-promoting complex subunit 4 WD40 domain	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC4_WD40,DUF4365,FGE-sulfatase,Metallophos,OmpA,PD40,Ras,TIR_2,WD40
LZS2_k127_4407454_2	1185876.BN8_04189	1.554e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,4NJ7X@976|Bacteroidetes,47NJZ@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_4407580_2	1121380.JNIW01000020_gene3621	3.35e-16	82.0	COG0723@1|root,COG0723@2|Bacteria,1WI5B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Rieske 2Fe-2S domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
LZS2_k127_4407580_1	247490.KSU1_D0841	2.555e-28	132.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2IX9E@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome b subunit of the bc complex	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B
LZS2_k127_4407580_0	608538.HTH_0156	2.353e-48	188.0	COG1148@1|root,COG1290@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	napF	-	-	ko:K02572,ko:K02573,ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	CCG,Cytochrome_B,FAD_binding_6,Fer2,Fer4,Fer4_4,Fer4_5,Fer4_7,FlpD,NAD_binding_1
LZS2_k127_4407580_3	324925.Ppha_1305	5.479e-12	70.0	COG1908@1|root,COG1908@2|Bacteria,1FEFC@1090|Chlorobi	1090|Chlorobi	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
LZS2_k127_4409340_0	1123325.JHUV01000010_gene1316	9.104e-12	74.0	COG5001@1|root,COG5001@2|Bacteria,2G441@200783|Aquificae	200783|Aquificae	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
LZS2_k127_4418046_1	4792.ETI45638	0.000299	53.0	COG2183@1|root,KOG1857@2759|Eukaryota,3QBJT@4776|Peronosporales	4776|Peronosporales	K	Photosystem II 12 kDa extrinsic protein (PsbU)	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,HHH_3
LZS2_k127_4418046_0	744979.R2A130_0970	2.829e-84	288.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2TTT6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
LZS2_k127_4441961_1	682795.AciX8_0673	9.221e-43	162.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria,2JIWQ@204432|Acidobacteriia	204432|Acidobacteriia	E	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
LZS2_k127_4441961_0	110663.KI911558_gene620	9.653e-69	245.0	COG0142@1|root,COG0142@2|Bacteria,1G0V7@1117|Cyanobacteria,1GZ8Q@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the FPP GGPP synthase family	sds	-	2.5.1.84,2.5.1.85	ko:K05356	ko00900,ko01110,map00900,map01110	-	R07267,R09250,R09251	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS2_k127_4441961_3	926560.KE387023_gene2909	7.001e-12	75.0	COG1648@1|root,COG1648@2|Bacteria,1WIA4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Siroheme synthase	-	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
LZS2_k127_4441961_2	1183438.GKIL_0226	3.886e-29	130.0	COG1333@1|root,COG1333@2|Bacteria,1G0R9@1117|Cyanobacteria	1117|Cyanobacteria	O	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment	ccs1	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
LZS2_k127_4460571_2	927677.ALVU02000001_gene1997	1.273e-43	166.0	COG0500@1|root,COG2226@2|Bacteria,1G0WT@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
LZS2_k127_4460571_0	1321778.HMPREF1982_01035	2.194e-83	287.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia	186801|Clostridia	E	Oxidoreductase NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_4460571_1	1128421.JAGA01000002_gene796	1.02e-61	217.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
LZS2_k127_4464111_0	886293.Sinac_1293	0.0004725	51.0	COG0457@1|root,COG0457@2|Bacteria,2J07X@203682|Planctomycetes	203682|Planctomycetes	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_4464111_1	398578.Daci_1299	0.0006472	48.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,4AD4K@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
LZS2_k127_4468123_1	373994.Riv7116_4346	4.135e-45	172.0	COG0030@1|root,COG0030@2|Bacteria,1G03N@1117|Cyanobacteria,1HIZG@1161|Nostocales	1117|Cyanobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
LZS2_k127_4468123_2	1183438.GKIL_0654	3.108e-44	173.0	COG1947@1|root,COG1947@2|Bacteria,1G0YY@1117|Cyanobacteria	1117|Cyanobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS2_k127_4468123_0	469371.Tbis_0205	9.54e-71	246.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4DXYV@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
LZS2_k127_4480571_1	1267533.KB906737_gene1841	1.793e-62	224.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS2_k127_4480571_2	67281.JNZZ01000015_gene6563	1.705e-21	104.0	COG2227@1|root,COG2227@2|Bacteria,2HYAN@201174|Actinobacteria,41AR3@629295|Streptomyces griseus group	201174|Actinobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_4480571_0	216594.MMAR_3972	1.207e-113	396.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,2GISR@201174|Actinobacteria,233YJ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
LZS2_k127_448344_0	9646.ENSAMEP00000015903	2.952e-18	97.0	COG2267@1|root,KOG1455@2759|Eukaryota,38I1Q@33154|Opisthokonta,3BHGS@33208|Metazoa,3CSYE@33213|Bilateria,483MQ@7711|Chordata,48WRH@7742|Vertebrata,3JEFX@40674|Mammalia,3EUJI@33554|Carnivora	33208|Metazoa	I	Monoglyceride lipase	MGLL	GO:0001558,GO:0001676,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005811,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006638,GO:0006639,GO:0006690,GO:0006950,GO:0006952,GO:0006954,GO:0007275,GO:0007399,GO:0008015,GO:0008150,GO:0008152,GO:0008277,GO:0008361,GO:0009056,GO:0009966,GO:0009987,GO:0010646,GO:0010648,GO:0010769,GO:0010975,GO:0012505,GO:0016020,GO:0016042,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019369,GO:0019752,GO:0019898,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023057,GO:0030154,GO:0030424,GO:0030516,GO:0031344,GO:0031347,GO:0031644,GO:0031974,GO:0031981,GO:0031984,GO:0032101,GO:0032501,GO:0032502,GO:0032535,GO:0032787,GO:0033267,GO:0033559,GO:0035150,GO:0035296,GO:0036155,GO:0040008,GO:0042175,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043196,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044057,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0045202,GO:0045595,GO:0045664,GO:0046461,GO:0046464,GO:0046486,GO:0046503,GO:0046983,GO:0047372,GO:0048167,GO:0048519,GO:0048523,GO:0048583,GO:0048638,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050727,GO:0050767,GO:0050770,GO:0050789,GO:0050793,GO:0050794,GO:0050804,GO:0050805,GO:0050880,GO:0050896,GO:0051128,GO:0051239,GO:0051930,GO:0051931,GO:0051960,GO:0052689,GO:0060284,GO:0060292,GO:0061387,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0080134,GO:0090066,GO:0097458,GO:0097746,GO:0097756,GO:0098827,GO:0099177,GO:0120025,GO:0120035,GO:0120038,GO:1901568,GO:1901575,GO:2000026,GO:2000124	3.1.1.23	ko:K01054	ko00561,ko01100,ko04714,ko04723,ko04923,map00561,map01100,map04714,map04723,map04923	M00098	R01351	RC00020,RC00041	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Hydrolase_4
LZS2_k127_448755_0	1449335.JQLG01000004_gene350	1.827e-78	279.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K07076,ko:K16263	-	-	-	-	ko00000,ko02000	2.A.3.13	-	-	AA_permease_2,Usp
LZS2_k127_448988_0	706587.Desti_0542	4.048e-48	180.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2MQ7A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
LZS2_k127_4493165_1	102232.GLO73106DRAFT_00034110	1.181e-82	286.0	COG4275@1|root,COG4275@2|Bacteria	2|Bacteria	S	Chromate resistance exported protein	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
LZS2_k127_4493165_2	1267535.KB906767_gene2010	4.225e-81	288.0	COG1538@1|root,COG1538@2|Bacteria,3Y3KB@57723|Acidobacteria,2JK7S@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS2_k127_4493165_3	1122621.ATZA01000020_gene4023	3.781e-25	113.0	COG0841@1|root,COG0841@2|Bacteria,4NG7I@976|Bacteroidetes,1INVR@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS2_k127_4493165_0	1038860.AXAP01000007_gene6044	2.883e-172	554.0	COG0841@1|root,COG0841@2|Bacteria,1R93M@1224|Proteobacteria,2UP7I@28211|Alphaproteobacteria,3K354@41294|Bradyrhizobiaceae	2|Bacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS2_k127_4493165_4	426114.THI_0443	5.592e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,1KKMD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
LZS2_k127_4503684_2	1226322.HMPREF1545_00442	2.042e-18	98.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,2N6H8@216572|Oscillospiraceae	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS2_k127_4503684_1	1445613.JALM01000199_gene3339	2.213e-24	111.0	2ATGG@1|root,31J05@2|Bacteria,2HNCP@201174|Actinobacteria,4E7XY@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4503684_0	858215.Thexy_0259	7.486e-101	347.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,42EN9@68295|Thermoanaerobacterales	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_4504867_0	1134474.O59_000004	2.351e-29	122.0	COG3757@1|root,COG3757@2|Bacteria,1N792@1224|Proteobacteria,1S6KA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycoside hydrolase, family	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
LZS2_k127_4507402_2	999541.bgla_2g26570	8.745e-34	138.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,2VR75@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_4507402_3	273116.14325523	3.35e-07	60.0	arCOG01806@1|root,arCOG01806@2157|Archaea,2Y0PI@28890|Euryarchaeota,242EI@183967|Thermoplasmata	183967|Thermoplasmata	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4507402_4	551115.Aazo_3466	1.254e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1HIPK@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_4507402_1	1157490.EL26_21110	3.036e-35	152.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_4507402_0	1128427.KB904821_gene2696	3.278e-38	154.0	COG0515@1|root,COG0515@2|Bacteria,1G10B@1117|Cyanobacteria,1H75J@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
LZS2_k127_4517403_1	1123376.AUIU01000015_gene446	2.035e-79	274.0	COG0330@1|root,COG0330@2|Bacteria,3J0NF@40117|Nitrospirae	40117|Nitrospirae	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_4517403_0	1089548.KI783301_gene1200	1.339e-87	307.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli,3WE4X@539002|Bacillales incertae sedis	91061|Bacilli	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
LZS2_k127_4532364_0	292563.Cyast_0816	4.705e-10	71.0	COG2267@1|root,COG2267@2|Bacteria,1G2EN@1117|Cyanobacteria	1117|Cyanobacteria	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_453500_0	945713.IALB_0046	2.906e-157	502.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	icd	-	1.1.1.41,1.1.1.42	ko:K00030,ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R00709,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS2_k127_4550908_0	269797.Mbar_A0699	3.725e-09	70.0	COG5549@1|root,arCOG04994@2157|Archaea,2XZZ9@28890|Euryarchaeota,2NARI@224756|Methanomicrobia	224756|Methanomicrobia	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
LZS2_k127_4560032_1	243232.MJ_1443	1.038e-08	62.0	COG4818@1|root,arCOG04344@2157|Archaea,2XZ6C@28890|Euryarchaeota,23R98@183939|Methanococci	183939|Methanococci	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
LZS2_k127_4560032_0	481448.Minf_0536	9.017e-298	929.0	COG1523@1|root,COG1523@2|Bacteria,46S5N@74201|Verrucomicrobia,37GBA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS2_k127_4560976_0	661367.LLO_1771	1.613e-48	183.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,1JD8G@118969|Legionellales	118969|Legionellales	S	ErfK YbiS YcfS YnhG family protein	lssA	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS2_k127_4560976_1	251221.35213978	4.059e-20	105.0	COG0810@1|root,COG1714@1|root,COG0810@2|Bacteria,COG1714@2|Bacteria,1GQMS@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM TonB family C-terminal domain	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	RDD,TonB_2
LZS2_k127_4560976_2	1123307.KB904393_gene28	1.768e-06	61.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	malC	GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
LZS2_k127_4568832_1	43989.cce_3614	2.648e-22	101.0	COG0515@1|root,COG0515@2|Bacteria,1G02X@1117|Cyanobacteria,3KFNR@43988|Cyanothece	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_4568832_0	118161.KB235922_gene4786	1.408e-40	168.0	COG0515@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1716@2|Bacteria,1G10B@1117|Cyanobacteria,3VJ4K@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
LZS2_k127_4570737_1	215803.DB30_0609	1.307e-70	246.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2YW0B@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS2_k127_4570737_0	638302.HMPREF0908_1378	1.851e-95	336.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4H2NH@909932|Negativicutes	909932|Negativicutes	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
LZS2_k127_4571476_0	861299.J421_4096	8.27e-50	194.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K07100	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_7,DLH,Peptidase_S9
LZS2_k127_4582471_2	1385935.N836_19710	3.593e-16	87.0	COG1249@1|root,COG1404@1|root,COG1249@2|Bacteria,COG1404@2|Bacteria,1GQNX@1117|Cyanobacteria	1117|Cyanobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored,SLH
LZS2_k127_4582471_0	485915.Dret_0884	2.493e-162	550.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2M8CS@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM SNF2-related protein	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
LZS2_k127_4582471_1	179408.Osc7112_5263	2.159e-24	115.0	COG1196@1|root,COG1724@1|root,COG1196@2|Bacteria,COG1724@2|Bacteria,1G68N@1117|Cyanobacteria,1HBR2@1150|Oscillatoriales	1117|Cyanobacteria	DN	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
LZS2_k127_459401_3	227882.SAV_6600	4.147e-09	63.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	mmgC	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_459401_0	983545.Glaag_4055	1.453e-73	259.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,466EE@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	LD-carboxypeptidase	ldcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	iAPECO1_1312.APECO1_304,iECABU_c1320.ECABU_c14580,iECED1_1282.ECED1_1334,iECOK1_1307.ECOK1_1338,iECS88_1305.ECS88_1255,iLF82_1304.LF82_1171,iNRG857_1313.NRG857_06085,iSFV_1184.SFV_1201,iSFxv_1172.SFxv_1357,iS_1188.S1271,iUMN146_1321.UM146_11125,iUTI89_1310.UTI89_C1378,ic_1306.c1641	Peptidase_S66
LZS2_k127_459401_2	745014.OMB55_00005680	3.339e-51	194.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,1J6J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Microcin C7 resistance	ldcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	iAPECO1_1312.APECO1_304,iECABU_c1320.ECABU_c14580,iECED1_1282.ECED1_1334,iECOK1_1307.ECOK1_1338,iECS88_1305.ECS88_1255,iLF82_1304.LF82_1171,iNRG857_1313.NRG857_06085,iSFV_1184.SFV_1201,iSFxv_1172.SFxv_1357,iS_1188.S1271,iUMN146_1321.UM146_11125,iUTI89_1310.UTI89_C1378,ic_1306.c1641	Peptidase_S66
LZS2_k127_459401_1	370438.PTH_0657	1.707e-71	252.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
LZS2_k127_4621673_0	886293.Sinac_2261	6.865e-85	294.0	COG1696@1|root,COG1696@2|Bacteria,2IX06@203682|Planctomycetes	203682|Planctomycetes	M	membrane protein involved in D-alanine	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
LZS2_k127_4621673_1	931276.Cspa_c19650	1.278e-05	57.0	COG2755@1|root,COG2755@2|Bacteria,1V5CJ@1239|Firmicutes,24IWV@186801|Clostridia,36JS6@31979|Clostridiaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4630782_1	1340493.JNIF01000003_gene2694	1.3e-105	360.0	COG1409@1|root,COG1409@2|Bacteria,3Y71A@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS2_k127_4630782_2	864702.OsccyDRAFT_2115	1.056e-08	61.0	COG5548@1|root,COG5548@2|Bacteria,1G997@1117|Cyanobacteria,1HDDM@1150|Oscillatoriales	1117|Cyanobacteria	S	Transmembrane proteins 14C	-	-	-	-	-	-	-	-	-	-	-	-	Tmemb_14
LZS2_k127_4630782_0	497965.Cyan7822_1581	6.181e-164	524.0	COG0436@1|root,COG0436@2|Bacteria,1G0M8@1117|Cyanobacteria,3KGRJ@43988|Cyanothece	1117|Cyanobacteria	H	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_4630980_0	868864.Dester_0119	6.366e-108	354.0	COG0458@1|root,COG0458@2|Bacteria,2G3RR@200783|Aquificae	200783|Aquificae	F	PFAM Carbamoyl-phosphate synthase L chain	carB2	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
LZS2_k127_4630980_3	1120965.AUBV01000009_gene3004	9.742e-15	86.0	COG2267@1|root,COG2267@2|Bacteria,4NQ59@976|Bacteroidetes,47R0A@768503|Cytophagia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_4630980_2	862908.BMS_3085	1.553e-49	182.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2MT6M@213481|Bdellovibrionales,2WP23@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	transferase hexapeptide	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
LZS2_k127_4630980_1	471223.GWCH70_2632	2.639e-76	271.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,1WFIA@129337|Geobacillus	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
LZS2_k127_4657573_1	1126627.BAWE01000002_gene846	0.0001239	53.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2TRSN@28211|Alphaproteobacteria,3JV15@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
LZS2_k127_4657573_0	198467.NP92_10605	5.322e-70	253.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,21WD0@150247|Anoxybacillus	91061|Bacilli	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS2_k127_4659684_0	118161.KB235922_gene1545	9.501e-47	182.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VI2D@52604|Pleurocapsales	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_4659684_1	1231241.Mc24_00115	1.354e-46	177.0	COG0745@1|root,COG0745@2|Bacteria,2GDZF@200918|Thermotogae	200918|Thermotogae	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_4666734_0	111780.Sta7437_3871	5.129e-08	64.0	2CJMF@1|root,2Z83E@2|Bacteria,1G10T@1117|Cyanobacteria,3VJ8R@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4666734_1	1297617.JPJD01000041_gene1830	3.106e-05	49.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,2699F@186813|unclassified Clostridiales	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
LZS2_k127_4669080_0	243233.MCA2288	7.947e-44	167.0	COG0079@1|root,COG0079@2|Bacteria,1MXDP@1224|Proteobacteria,1RR2V@1236|Gammaproteobacteria,1XFZQ@135618|Methylococcales	135618|Methylococcales	E	Aminotransferase class I and II	-	-	-	ko:K02225	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002	-	-	-	Aminotran_1_2
LZS2_k127_4669080_1	1254432.SCE1572_07800	5.927e-39	165.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_4675997_2	1499967.BAYZ01000005_gene5430	4.273e-50	186.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS2_k127_4675997_3	313606.M23134_01445	2.965e-08	65.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4NPFW@976|Bacteroidetes,47X9T@768503|Cytophagia	976|Bacteroidetes	DZ	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	DUF5013,TIG
LZS2_k127_4675997_0	862908.BMS_1123	1.133e-67	245.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,42UMU@68525|delta/epsilon subdivisions,2MSSJ@213481|Bdellovibrionales,2WRRN@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	DAO
LZS2_k127_4675997_1	1173020.Cha6605_5527	1.075e-56	204.0	COG1186@1|root,COG1186@2|Bacteria,1G1QH@1117|Cyanobacteria	1117|Cyanobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS2_k127_4699748_1	448385.sce0906	1.266e-22	98.0	COG0122@1|root,COG0350@1|root,COG0122@2|Bacteria,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,43ARM@68525|delta/epsilon subdivisions,2X65K@28221|Deltaproteobacteria,2Z392@29|Myxococcales	28221|Deltaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,HhH-GPD
LZS2_k127_4699748_0	1121920.AUAU01000004_gene745	4.495e-41	165.0	COG0506@1|root,COG0506@2|Bacteria,3Y2G8@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
LZS2_k127_470398_2	338969.Rfer_1815	1.619e-05	56.0	2EIBB@1|root,32XEP@2|Bacteria,1MZDG@1224|Proteobacteria,2VUEA@28216|Betaproteobacteria,4AHAP@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_470398_0	46234.ANA_C10561	1.149e-106	368.0	COG0465@1|root,COG0465@2|Bacteria,1G1S2@1117|Cyanobacteria,1HKEH@1161|Nostocales	1117|Cyanobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH4	GO:0003674,GO:0003824,GO:0004176,GO:0006091,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009644,GO:0009765,GO:0009892,GO:0009987,GO:0010109,GO:0010205,GO:0010206,GO:0010304,GO:0015979,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0019684,GO:0030091,GO:0030163,GO:0031323,GO:0031324,GO:0042548,GO:0042623,GO:0043155,GO:0043170,GO:0043467,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1905156	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_4719138_1	1540221.JQNI01000002_gene2505	1.478e-65	239.0	COG0380@1|root,COG0380@2|Bacteria,1WI3G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	alpha,alpha-trehalose-phosphate synthase	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
LZS2_k127_4719138_2	1173022.Cri9333_3478	2.843e-35	141.0	COG0713@1|root,COG0713@2|Bacteria,1G6KK@1117|Cyanobacteria,1HBH9@1150|Oscillatoriales	1117|Cyanobacteria	C	electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration	ndhE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K05576	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q2
LZS2_k127_4719138_5	582515.KR51_00020560	1.6e-18	93.0	COG0839@1|root,COG0839@2|Bacteria,1G2WH@1117|Cyanobacteria	1117|Cyanobacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K05578	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_q3
LZS2_k127_4719138_4	1340493.JNIF01000003_gene2480	1.38e-24	114.0	COG1143@1|root,COG1143@2|Bacteria,3Y529@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
LZS2_k127_4719138_0	945713.IALB_1626	5.889e-71	257.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114	1.6.5.3	ko:K00337,ko:K05572	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS2_k127_4719138_3	1174504.AJTN02000207_gene3356	1.307e-32	130.0	COG0649@1|root,COG0649@2|Bacteria,1TQAR@1239|Firmicutes,4HA4Y@91061|Bacilli,1ZBPG@1386|Bacillus	91061|Bacilli	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
LZS2_k127_4722610_0	1382304.JNIL01000001_gene670	1.311e-37	151.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_4722610_1	1173024.KI912152_gene501	1.092e-19	99.0	2CA71@1|root,2ZFTQ@2|Bacteria,1G57X@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_474755_0	1380355.JNIJ01000018_gene4436	2.62e-217	706.0	COG2203@1|root,COG3899@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3JR6P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	fixL	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,CHASE3,DUF4118,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9
LZS2_k127_474878_7	373994.Riv7116_6075	1.571e-17	95.0	COG1670@1|root,COG1994@1|root,COG1670@2|Bacteria,COG1994@2|Bacteria,1GFNN@1117|Cyanobacteria,1HSNP@1161|Nostocales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
LZS2_k127_474878_3	1487953.JMKF01000021_gene2194	5.112e-42	166.0	COG0805@1|root,COG0805@2|Bacteria,1FZZ8@1117|Cyanobacteria,1H7K2@1150|Oscillatoriales	1117|Cyanobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
LZS2_k127_474878_1	1128398.Curi_c08580	3.283e-44	171.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,268GU@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
LZS2_k127_474878_2	113355.CM001775_gene212	3.9e-43	160.0	COG0292@1|root,COG0292@2|Bacteria,1G5NZ@1117|Cyanobacteria	1117|Cyanobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
LZS2_k127_474878_8	1408323.JQKK01000002_gene1759	1.827e-10	63.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,27PJB@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
LZS2_k127_474878_0	43989.cce_2578	1.963e-57	205.0	COG0290@1|root,COG0290@2|Bacteria,1G0WC@1117|Cyanobacteria,3KGNJ@43988|Cyanothece	1117|Cyanobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
LZS2_k127_474878_4	1127695.HMPREF9163_02242	1.894e-28	115.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4H53V@909932|Negativicutes	909932|Negativicutes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
LZS2_k127_474878_5	643648.Slip_2347	5.507e-21	97.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,42K2A@68298|Syntrophomonadaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS2_k127_474878_6	1173263.Syn7502_02227	1.329e-17	87.0	COG0360@1|root,COG0360@2|Bacteria,1G864@1117|Cyanobacteria,1H0IC@1129|Synechococcus	1117|Cyanobacteria	J	Binds together with S18 to 16S ribosomal RNA	rps6	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
LZS2_k127_475253_1	471855.Shel_03780	9.415e-08	61.0	COG1413@1|root,COG1413@2|Bacteria,2I6JW@201174|Actinobacteria,4CXTN@84998|Coriobacteriia	84998|Coriobacteriia	C	Leucine rich repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_475253_0	1341151.ASZU01000008_gene1395	4.926e-56	217.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27B9F@186824|Thermoactinomycetaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_475253_2	306281.AJLK01000150_gene1957	0.000683	47.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	AAA,ClpS
LZS2_k127_4753138_3	204669.Acid345_3543	8.779e-06	54.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR
LZS2_k127_4753138_4	998674.ATTE01000001_gene4366	4.049e-05	56.0	COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria	1224|Proteobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
LZS2_k127_4753138_2	153721.MYP_2783	1.094e-100	347.0	28JBJ@1|root,2Z968@2|Bacteria,4NKZ3@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4753138_1	326427.Cagg_2222	9.576e-184	590.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,375BH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS2_k127_4753138_0	1303518.CCALI_00064	2.029e-195	627.0	COG2759@1|root,COG2759@2|Bacteria	2|Bacteria	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FTHFS
LZS2_k127_4753883_0	1088721.NSU_2478	4.266e-13	70.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K02W@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidase M13	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
LZS2_k127_4753883_1	861299.J421_2118	1.009e-11	78.0	COG5549@1|root,COG5549@2|Bacteria,1ZTQC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Matrixin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
LZS2_k127_4764086_0	251229.Chro_1602	1.722e-22	106.0	COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,1GBM2@1117|Cyanobacteria	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
LZS2_k127_4768808_0	1033743.CAES01000078_gene3839	1.561e-52	193.0	COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli,26TD7@186822|Paenibacillaceae	91061|Bacilli	S	glycosyl transferase family 2	galnac-T15	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2
LZS2_k127_4768808_1	313598.MED152_05615	1.984e-22	109.0	COG0451@1|root,COG0451@2|Bacteria,4PIU8@976|Bacteroidetes,1IM83@117743|Flavobacteriia,3VXEP@52959|Polaribacter	976|Bacteroidetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS2_k127_4774157_1	82654.Pse7367_0157	1.158e-05	53.0	COG1408@1|root,COG1408@2|Bacteria,1G286@1117|Cyanobacteria,1HGYK@1150|Oscillatoriales	1117|Cyanobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS2_k127_4774157_0	391625.PPSIR1_20759	9.902e-12	69.0	COG1408@1|root,COG1408@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS2_k127_4776441_1	1117314.PCIT_16200	7.728e-10	69.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,1RZ0R@1236|Gammaproteobacteria,2Q0TU@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	epimerase, PhzC PhzF homolog	yddE_1	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
LZS2_k127_4776441_0	2002.JOEQ01000010_gene6231	1.218e-10	66.0	COG0026@1|root,COG0026@2|Bacteria,2I3IE@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
LZS2_k127_4776661_3	1499967.BAYZ01000005_gene5430	0.0002798	45.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS2_k127_4776661_1	326427.Cagg_0596	1.709e-26	113.0	COG1454@1|root,COG1454@2|Bacteria,2GBSR@200795|Chloroflexi,375PH@32061|Chloroflexia	32061|Chloroflexia	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4776661_0	765420.OSCT_3062	2.459e-80	281.0	COG1454@1|root,COG1454@2|Bacteria,2G6IU@200795|Chloroflexi,37537@32061|Chloroflexia	32061|Chloroflexia	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
LZS2_k127_4776661_2	1463917.JODC01000005_gene6721	3.087e-16	82.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	glkA	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS2_k127_4783733_1	204669.Acid345_2949	5.495e-115	386.0	COG4805@1|root,COG4805@2|Bacteria,3Y468@57723|Acidobacteria,2JP3U@204432|Acidobacteriia	204432|Acidobacteriia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
LZS2_k127_4783733_2	204669.Acid345_2949	1.528e-68	236.0	COG4805@1|root,COG4805@2|Bacteria,3Y468@57723|Acidobacteria,2JP3U@204432|Acidobacteriia	204432|Acidobacteriia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
LZS2_k127_4783733_0	1183438.GKIL_2044	1.69e-219	707.0	COG3696@1|root,COG3696@2|Bacteria,1GE7Y@1117|Cyanobacteria	1117|Cyanobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K11326	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1	-	-	ACR_tran
LZS2_k127_4786536_1	642492.Clole_0070	7.973e-15	85.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia	186801|Clostridia	CP	ABC-2 type transporter	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
LZS2_k127_4786536_0	1340493.JNIF01000003_gene2272	4.407e-81	276.0	COG4555@1|root,COG4555@2|Bacteria,3Y9E2@57723|Acidobacteria	57723|Acidobacteria	CP	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS2_k127_4786536_2	431943.CKL_3012	1.642e-07	59.0	COG1668@1|root,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,36GGI@31979|Clostridiaceae	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
LZS2_k127_4802408_1	1442598.JABW01000009_gene177	5.075e-73	250.0	COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria	1224|Proteobacteria	L	Site-specific recombinases DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
LZS2_k127_4802408_0	56107.Cylst_5603	4.904e-245	781.0	COG4644@1|root,COG4644@2|Bacteria,1G1K1@1117|Cyanobacteria,1HMWR@1161|Nostocales	1117|Cyanobacteria	L	Tn3 transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
LZS2_k127_4809473_2	272134.KB731324_gene4887	4.04e-05	55.0	COG0515@1|root,COG1357@1|root,COG0515@2|Bacteria,COG1357@2|Bacteria,1G1YH@1117|Cyanobacteria,1H88P@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Serine threonine-protein kinase B	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pentapeptide,Pkinase
LZS2_k127_4809473_0	873447.SPB_1135	5.704e-24	109.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli	91061|Bacilli	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_4809473_1	1123487.KB892835_gene3443	3.523e-22	111.0	COG4564@1|root,COG4564@2|Bacteria,1QTY1@1224|Proteobacteria,2VKWI@28216|Betaproteobacteria,2KV4U@206389|Rhodocyclales	206389|Rhodocyclales	T	Cache 3/Cache 2 fusion domain	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,sCache_2
LZS2_k127_4818878_0	1045855.DSC_02295	3.706e-79	285.0	COG2730@1|root,COG2730@2|Bacteria,1MV2T@1224|Proteobacteria,1S3MN@1236|Gammaproteobacteria,1X5CM@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
LZS2_k127_4818878_1	1173027.Mic7113_2713	2.588e-16	81.0	COG4108@1|root,COG4108@2|Bacteria,1G0Y8@1117|Cyanobacteria,1H72K@1150|Oscillatoriales	1117|Cyanobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
LZS2_k127_4821834_3	203124.Tery_1748	0.0005888	46.0	COG2804@1|root,COG2804@2|Bacteria,1G03J@1117|Cyanobacteria,1H8SV@1150|Oscillatoriales	1117|Cyanobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
LZS2_k127_4821834_0	1385935.N836_08275	1.969e-128	421.0	COG2805@1|root,COG2805@2|Bacteria,1G0HI@1117|Cyanobacteria,1H7W0@1150|Oscillatoriales	1117|Cyanobacteria	NU	PFAM Type II IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS2_k127_4821834_1	1170562.Cal6303_1797	1.403e-110	370.0	COG1459@1|root,COG1459@2|Bacteria,1G164@1117|Cyanobacteria,1HKUS@1161|Nostocales	1117|Cyanobacteria	U	PFAM Bacterial type II secretion system protein F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
LZS2_k127_4821834_2	1122611.KB904000_gene8135	0.0001291	46.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4EGY2@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
LZS2_k127_4823354_0	1127695.HMPREF9163_02405	1.275e-30	125.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4H26Q@909932|Negativicutes	909932|Negativicutes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
LZS2_k127_4846865_2	134676.ACPL_1314	1.627e-32	130.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4DCRN@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
LZS2_k127_4846865_3	1410653.JHVC01000001_gene1390	1.417e-30	134.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Peptidase_S9
LZS2_k127_4846865_0	215803.DB30_3165	4.113e-61	219.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria,2YV5K@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS2_k127_4846865_1	593907.Celgi_2221	1.961e-46	178.0	COG0189@1|root,COG0189@2|Bacteria,2HI2Z@201174|Actinobacteria,4F1V4@85016|Cellulomonadaceae	201174|Actinobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
LZS2_k127_4846865_4	1183438.GKIL_4366	1.55e-13	78.0	COG1842@1|root,COG1842@2|Bacteria,1G1GX@1117|Cyanobacteria	1117|Cyanobacteria	KT	Phage shock protein A (IM30) suppresses sigma54-dependent transcription	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
LZS2_k127_4856591_7	1234679.BN424_245	4.807e-11	68.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4HB03@91061|Bacilli,27G67@186828|Carnobacteriaceae	91061|Bacilli	E	NeuB family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS2_k127_4856591_1	65393.PCC7424_2681	3.241e-59	220.0	COG2038@1|root,COG2038@2|Bacteria,1G00Q@1117|Cyanobacteria,3KHIM@43988|Cyanothece	1117|Cyanobacteria	F	Belongs to the UPF0284 family	cobT	-	-	-	-	-	-	-	-	-	-	-	DBI_PRT
LZS2_k127_4856591_5	694431.DESACE_05840	2.775e-28	130.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WMXZ@28221|Deltaproteobacteria,2M6IC@213113|Desulfurellales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
LZS2_k127_4856591_0	1121422.AUMW01000003_gene869	2.088e-136	445.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,260KZ@186807|Peptococcaceae	186801|Clostridia	I	PFAM Acyl-CoA dehydrogenase, C-terminal domain	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin
LZS2_k127_4856591_6	1267534.KB906755_gene3911	1.056e-14	84.0	COG0484@1|root,COG0484@2|Bacteria,3Y8AR@57723|Acidobacteria	57723|Acidobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
LZS2_k127_4856591_3	1313301.AUGC01000010_gene965	3.074e-44	171.0	COG0164@1|root,COG0164@2|Bacteria,4NGVR@976|Bacteroidetes	976|Bacteroidetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS2_k127_4856591_2	1131462.DCF50_p2144	8.403e-49	186.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,260QB@186807|Peptococcaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
LZS2_k127_4856591_4	395961.Cyan7425_0439	1.205e-39	150.0	COG0335@1|root,COG0335@2|Bacteria,1G5QG@1117|Cyanobacteria,3KI0B@43988|Cyanothece	1117|Cyanobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
LZS2_k127_4856882_1	324057.Pjdr2_0749	1.063e-37	153.0	COG3878@1|root,COG3878@2|Bacteria,1V0V3@1239|Firmicutes,4HMIQ@91061|Bacilli,26X0A@186822|Paenibacillaceae	91061|Bacilli	E	Domain of unknown function (DUF1963)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
LZS2_k127_4856882_0	1242864.D187_001409	1.694e-90	310.0	COG0240@1|root,COG0240@2|Bacteria,1MXI9@1224|Proteobacteria,42TEU@68525|delta/epsilon subdivisions,2WPTF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM NAD NADP octopine nopaline dehydrogenase	-	-	1.5.1.28	ko:K04940	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored,Octopine_DH
LZS2_k127_4856882_2	176946.XP_007420595.1	7.249e-24	102.0	KOG3947@1|root,KOG3947@2759|Eukaryota,39RNM@33154|Opisthokonta,3BDZ6@33208|Metazoa,3CWXR@33213|Bilateria,485B1@7711|Chordata,4935P@7742|Vertebrata	33208|Metazoa	S	Metallophosphoesterase domain-containing protein 1	MPPED1	GO:0003674,GO:0005488,GO:0005515	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS2_k127_4857348_1	406327.Mevan_0576	1.143e-07	64.0	COG0727@1|root,arCOG05059@2157|Archaea,2XWKN@28890|Euryarchaeota,23QSV@183939|Methanococci	183939|Methanococci	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
LZS2_k127_4857348_0	1288963.ADIS_4221	1.513e-121	395.0	COG1012@1|root,COG1012@2|Bacteria,4NIC8@976|Bacteroidetes,47KER@768503|Cytophagia	976|Bacteroidetes	C	Aldehyde dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS2_k127_4861180_0	504728.K649_05265	5.759e-87	304.0	COG1680@1|root,COG1680@2|Bacteria,1WMGA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS2_k127_4861180_1	1423790.BN53_06530	5.535e-42	175.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_4870206_0	59931.WH7805_04456	1.076e-248	779.0	COG0542@1|root,COG0542@2|Bacteria,1G0ZH@1117|Cyanobacteria,1GYXV@1129|Synechococcus	1117|Cyanobacteria	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_4870206_2	588581.Cpap_4001	6.88e-08	62.0	COG0790@1|root,COG0790@2|Bacteria,1TS5X@1239|Firmicutes,248TS@186801|Clostridia	186801|Clostridia	KLT	Psort location	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_16,TPR_7,TPR_8
LZS2_k127_4870206_1	1123376.AUIU01000018_gene50	1.155e-86	296.0	COG0668@1|root,COG0668@2|Bacteria,3J0YK@40117|Nitrospirae	40117|Nitrospirae	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
LZS2_k127_487313_0	566461.SSFG_01945	2.959e-23	106.0	COG0406@1|root,COG0406@2|Bacteria,2GN7B@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
LZS2_k127_487313_1	290399.Arth_0120	1.646e-20	100.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	cobC	-	3.1.3.3,3.1.3.73,3.1.3.85	ko:K02226,ko:K22305,ko:K22306	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
LZS2_k127_487313_2	700598.Niako_1039	4.907e-06	58.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1,SEFIR
LZS2_k127_4885079_0	215803.DB30_8752	3.991e-61	231.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4346X@68525|delta/epsilon subdivisions,2XA3R@28221|Deltaproteobacteria,2YXWE@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_4899376_0	1341155.FSS13T_07660	1.373e-31	141.0	COG0705@1|root,COG0705@2|Bacteria,4NP9G@976|Bacteroidetes,1IDFI@117743|Flavobacteriia,2NY9B@237|Flavobacterium	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
LZS2_k127_4902351_0	237368.SCABRO_01667	2.545e-78	269.0	COG3930@1|root,COG3930@2|Bacteria,2J4QT@203682|Planctomycetes	203682|Planctomycetes	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
LZS2_k127_4902351_1	252305.OB2597_12081	1.675e-37	150.0	COG0515@1|root,COG0515@2|Bacteria,1QVSB@1224|Proteobacteria,2TWKG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4902351_2	404380.Gbem_1837	1.363e-17	94.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,42S07@68525|delta/epsilon subdivisions,2WNR0@28221|Deltaproteobacteria,43UG0@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ChapFlgA,RcpC,SAF
LZS2_k127_4906738_0	1280950.HJO_11277	4.231e-74	254.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2TTWF@28211|Alphaproteobacteria,43YZF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	NADPH quinone	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_4906738_1	1121430.JMLG01000006_gene1724	2.328e-52	209.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_4925685_1	1122164.JHWF01000026_gene344	4.706e-21	104.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1JCSU@118969|Legionellales	118969|Legionellales	S	Sel1-like repeats.	-	-	-	ko:K15474	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	Sel1
LZS2_k127_4925685_0	113355.CM001775_gene2675	8.094e-23	111.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	113355.CM001775_gene2675|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4927940_2	272134.KB731324_gene919	8.594e-19	88.0	COG4221@1|root,COG4221@2|Bacteria,1G3IS@1117|Cyanobacteria,1HG2Y@1150|Oscillatoriales	1117|Cyanobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_4927940_1	1121035.AUCH01000014_gene2350	2.966e-23	110.0	2C854@1|root,30DR2@2|Bacteria,1RFAR@1224|Proteobacteria,2W2IN@28216|Betaproteobacteria,2KYTM@206389|Rhodocyclales	206389|Rhodocyclales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS2_k127_4927940_0	195253.Syn6312_1746	1.515e-32	131.0	COG1733@1|root,COG1733@2|Bacteria,1G6MC@1117|Cyanobacteria,1H395@1129|Synechococcus	1117|Cyanobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
LZS2_k127_4936626_1	765420.OSCT_0036	3.43e-40	154.0	COG4251@1|root,COG4251@2|Bacteria,2G8Q2@200795|Chloroflexi,3777E@32061|Chloroflexia	32061|Chloroflexia	T	PAS PAC sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
LZS2_k127_4936626_2	43354.JOIJ01000001_gene436	9.224e-37	158.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4DXF3@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_4936626_0	1192034.CAP_6737	2.399e-54	211.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439IS@68525|delta/epsilon subdivisions,2X4V7@28221|Deltaproteobacteria,2YZNY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_4936626_3	546414.Deide_01860	3.31e-20	94.0	COG0784@1|root,COG0784@2|Bacteria,1WMM2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_4936706_0	926561.KB900617_gene1784	1.103e-251	788.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WA95@53433|Halanaerobiales	186801|Clostridia	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
LZS2_k127_4936706_2	29581.BW37_01218	5.367e-10	71.0	2D4IF@1|root,32TH7@2|Bacteria,1MZW6@1224|Proteobacteria,2VUY3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Suppressor of fused protein (SUFU)	-	-	-	-	-	-	-	-	-	-	-	-	SUFU
LZS2_k127_4936706_1	1131266.ARWQ01000013_gene65	1.537e-103	343.0	COG0451@1|root,arCOG01369@2157|Archaea	2157|Archaea	M	NAD-dependent epimerase dehydratase	-	-	5.1.3.10,5.1.3.2	ko:K01784,ko:K12454	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984,R04266	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS2_k127_4986436_3	1094489.BAnh1_10520	6.414e-18	87.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,2U1TN@28211|Alphaproteobacteria,48TZ8@772|Bartonellaceae	28211|Alphaproteobacteria	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
LZS2_k127_4986436_4	1184267.A11Q_1455	2.448e-11	68.0	COG1396@1|root,COG1396@2|Bacteria,1NGFD@1224|Proteobacteria	1224|Proteobacteria	K	TRANSCRIPTIONal	-	-	-	ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_19,HTH_3,HTH_31
LZS2_k127_4986436_2	880072.Desac_2637	2.901e-25	120.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2MQCA@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS2_k127_4986436_1	1170562.Cal6303_4333	2.2e-59	211.0	COG2201@1|root,COG2201@2|Bacteria,1G50Z@1117|Cyanobacteria,1HIJH@1161|Nostocales	1117|Cyanobacteria	NT	PFAM CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
LZS2_k127_4986436_0	99598.Cal7507_5109	5.189e-123	405.0	COG1352@1|root,COG1352@2|Bacteria,1G1W9@1117|Cyanobacteria,1HK56@1161|Nostocales	1117|Cyanobacteria	NT	PFAM CheR methyltransferase, SAM binding domain	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheR,CheR_N,PAS,PAS_4,PAS_9
LZS2_k127_498875_0	323097.Nham_3447	1.743e-75	259.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2VDR0@28211|Alphaproteobacteria,3JWZN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Respiratory nitrate reductase beta C-terminal	narH	-	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Fer4_11,Nitr_red_bet_C
LZS2_k127_498875_2	314278.NB231_16093	1.207e-12	75.0	COG2180@1|root,COG2180@2|Bacteria,1NBVT@1224|Proteobacteria	1224|Proteobacteria	C	nitrate reductase molybdenum cofactor assembly chaperone	-	-	-	ko:K00373	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Nitrate_red_del
LZS2_k127_498875_1	118005.AWNK01000001_gene2108	2.694e-54	205.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	narI	GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204	1.7.5.1	ko:K00370,ko:K00374,ko:K02575	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00615,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.1.8,5.A.3.1	-	iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897	Nitrate_red_gam
LZS2_k127_498875_3	68194.JNXR01000047_gene1651	0.0001942	53.0	COG2146@1|root,COG2146@2|Bacteria,2IKSY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
LZS2_k127_4998256_1	338966.Ppro_2940	5.162e-76	259.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43T5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
LZS2_k127_4998256_4	1382304.JNIL01000001_gene667	2.864e-17	83.0	COG0227@1|root,COG0227@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
LZS2_k127_4998256_0	195250.CM001776_gene427	2.599e-82	282.0	COG1281@1|root,COG1281@2|Bacteria,1G137@1117|Cyanobacteria,1GZ62@1129|Synechococcus	1117|Cyanobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
LZS2_k127_4998256_3	1232452.BAIB02000007_gene1674	4.562e-47	181.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,2692W@186813|unclassified Clostridiales	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
LZS2_k127_4998256_2	1173026.Glo7428_0957	1.098e-55	198.0	COG0216@1|root,COG0216@2|Bacteria,1FZY4@1117|Cyanobacteria	1117|Cyanobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS2_k127_5009460_0	112098.XP_008612521.1	1.018e-66	238.0	2D5D1@1|root,2SY4T@2759|Eukaryota	2759|Eukaryota	S	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
LZS2_k127_5009460_1	330214.NIDE1515	4.535e-62	220.0	COG0312@1|root,COG0312@2|Bacteria,3J0P7@40117|Nitrospirae	40117|Nitrospirae	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS2_k127_5017764_2	1123326.JFBL01000002_gene1670	5.069e-13	81.0	COG1721@1|root,COG1721@2|Bacteria,1RA3X@1224|Proteobacteria,42UN9@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS2_k127_5017764_1	1120973.AQXL01000109_gene1906	1.428e-26	128.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,4HB2E@91061|Bacilli,27897@186823|Alicyclobacillaceae	91061|Bacilli	E	Transglutaminase/protease-like homologues	yebA	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
LZS2_k127_5017764_0	521674.Plim_3352	4.249e-124	411.0	COG0464@1|root,COG0464@2|Bacteria,2IX7A@203682|Planctomycetes	203682|Planctomycetes	O	growth	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5033407_0	1123242.JH636434_gene3744	1.423e-32	134.0	COG1574@1|root,COG1574@2|Bacteria,2IXY4@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS2_k127_5033407_1	710686.Mycsm_06442	1.984e-05	57.0	COG3118@1|root,COG3118@2|Bacteria,2IHQV@201174|Actinobacteria,239GK@1762|Mycobacteriaceae	201174|Actinobacteria	O	TIGRFAM Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
LZS2_k127_5051389_2	398720.MED217_13099	8.089e-11	74.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,4NS5V@976|Bacteroidetes	976|Bacteroidetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_1,TPR_16,TPR_2,TPR_8
LZS2_k127_5051389_0	402777.KB235903_gene2012	4.109e-95	321.0	COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,1H7N7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS2_k127_5051389_1	1444309.JAQG01000032_gene3018	8.153e-63	226.0	COG0654@1|root,COG0654@2|Bacteria,1V6WA@1239|Firmicutes,4IRII@91061|Bacilli,276SV@186822|Paenibacillaceae	91061|Bacilli	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS2_k127_507239_1	1123290.AUDQ01000002_gene2372	1.405e-32	132.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,4HAWW@91061|Bacilli,26DKE@186818|Planococcaceae	91061|Bacilli	EH	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction	dat	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
LZS2_k127_507239_2	1385513.N780_04665	1.166e-09	68.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,2Y9WN@289201|Pontibacillus	91061|Bacilli	S	Tetratricopeptide repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_507239_0	5786.XP_003292112.1	2.043e-41	161.0	298QU@1|root,2RFRW@2759|Eukaryota,3XF3U@554915|Amoebozoa	554915|Amoebozoa	S	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
LZS2_k127_507239_3	439235.Dalk_4427	7.796e-05	47.0	2953F@1|root,2ZSG5@2|Bacteria,1NESI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5098509_0	760192.Halhy_1671	4.386e-09	69.0	COG4249@1|root,COG4249@2|Bacteria,4NIFD@976|Bacteroidetes	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
LZS2_k127_5098509_1	1122605.KB893647_gene306	3.706e-07	56.0	28QZH@1|root,2ZDEB@2|Bacteria,4P748@976|Bacteroidetes,1IZN4@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5099792_0	1183438.GKIL_3798	4.832e-49	188.0	COG2197@1|root,COG2197@2|Bacteria,1G1P0@1117|Cyanobacteria	1117|Cyanobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_5099792_1	330214.NIDE0805	7.134e-21	99.0	COG0784@1|root,COG2198@1|root,COG2203@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,3J0ZF@40117|Nitrospirae	2|Bacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_5109930_2	1229172.JQFA01000004_gene596	9.874e-15	79.0	COG1569@1|root,COG1569@2|Bacteria,1G7ZZ@1117|Cyanobacteria,1HCQ7@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
LZS2_k127_5109930_0	1283300.ATXB01000001_gene1267	4.904e-194	623.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1RP2N@1236|Gammaproteobacteria,1XE30@135618|Methylococcales	135618|Methylococcales	G	TIGRFAM malto-oligosyltrehalose trehalohydrolase	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
LZS2_k127_5109930_1	1183438.GKIL_3624	2.839e-88	308.0	COG1073@1|root,COG1073@2|Bacteria,1GAUD@1117|Cyanobacteria	1117|Cyanobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
LZS2_k127_5122799_1	1337936.IJ00_03240	1.379e-67	243.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1HJFJ@1161|Nostocales	1117|Cyanobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
LZS2_k127_5122799_0	1297569.MESS2_p100001	6.348e-86	299.0	COG1181@1|root,COG1181@2|Bacteria,1R4RC@1224|Proteobacteria,2U0HF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
LZS2_k127_5122799_3	1122169.AREN01000034_gene2803	8.539e-05	53.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,1RM8T@1236|Gammaproteobacteria,1JD4H@118969|Legionellales	118969|Legionellales	EG	EamA-like transporter family	eamA	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
LZS2_k127_5122799_2	1298920.KI911353_gene939	6.212e-05	48.0	COG2897@1|root,COG2897@2|Bacteria,1TS7E@1239|Firmicutes,24CNW@186801|Clostridia,21YTK@1506553|Lachnoclostridium	186801|Clostridia	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.11,2.8.1.2	ko:K01011,ko:K21028	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106,R07461	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
LZS2_k127_5126562_0	756272.Plabr_2946	1.577e-08	66.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	BTB,LRR_1,LRR_6
LZS2_k127_5126562_2	696747.NIES39_L00950	0.0002151	49.0	COG1950@1|root,COG1950@2|Bacteria,1G7RB@1117|Cyanobacteria,1HC6H@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
LZS2_k127_5126562_1	883126.HMPREF9710_05169	1.147e-07	57.0	2DRCV@1|root,33B8R@2|Bacteria,1R3NN@1224|Proteobacteria	1224|Proteobacteria	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
LZS2_k127_5128371_0	1183438.GKIL_3622	6.745e-59	209.0	COG3408@1|root,COG3408@2|Bacteria,1G2J4@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Amylo-alpha-16-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
LZS2_k127_5128371_1	797114.C475_08041	1.415e-40	161.0	COG0380@1|root,arCOG02831@2157|Archaea,2XSTE@28890|Euryarchaeota,23TQX@183963|Halobacteria	183963|Halobacteria	G	COG0380 Trehalose-6-phosphate synthase	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
LZS2_k127_5155125_0	391625.PPSIR1_39355	7.11e-51	200.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PP2C_2,Pkinase,TPR_12,TPR_8
LZS2_k127_5156668_0	203122.Sde_0075	1.648e-81	275.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,466MM@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
LZS2_k127_5156668_1	215803.DB30_8576	1.598e-53	198.0	COG5368@1|root,COG5368@2|Bacteria,1NX2K@1224|Proteobacteria	1224|Proteobacteria	N	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
LZS2_k127_5167080_0	398527.Bphyt_4546	1.68e-05	47.0	COG1247@1|root,COG1247@2|Bacteria,1N8HA@1224|Proteobacteria,2WGHC@28216|Betaproteobacteria,1K7HH@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_5169632_3	1242864.D187_003557	1.831e-41	165.0	COG0665@1|root,COG0665@2|Bacteria,1NCJX@1224|Proteobacteria,431XD@68525|delta/epsilon subdivisions,2WWSZ@28221|Deltaproteobacteria,2YUQQ@29|Myxococcales	28221|Deltaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.3	ko:K00273	ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146	-	R00366,R02457,R02894,R02923,R04221,R07400	RC00006,RC00018,RC00135	ko00000,ko00001,ko01000	-	-	-	DAO
LZS2_k127_5169632_1	72558.CBQ73140	1.18e-70	269.0	COG0031@1|root,KOG1252@2759|Eukaryota,39JHN@33154|Opisthokonta,3Q3UR@4751|Fungi,3UZRC@5204|Basidiomycota,3N39W@452284|Ustilaginomycotina	4751|Fungi	E	Rhodanese Homology Domain	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Rhodanese
LZS2_k127_5169632_0	1229276.DI53_2469	3.818e-96	331.0	COG0019@1|root,COG0019@2|Bacteria,4NGQF@976|Bacteroidetes	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
LZS2_k127_5169632_4	574376.BAMA_02930	1.151e-35	145.0	COG1028@1|root,COG1028@2|Bacteria,1V54X@1239|Firmicutes,4IS74@91061|Bacilli,1ZH69@1386|Bacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_5169632_2	867845.KI911784_gene1315	2.546e-64	234.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi,376G2@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
LZS2_k127_5169632_5	43228.XP_007733610.1	8.456e-05	46.0	COG0665@1|root,KOG3923@2759|Eukaryota,39SQP@33154|Opisthokonta,3P2MY@4751|Fungi,3QUQ7@4890|Ascomycota,20N65@147545|Eurotiomycetes	4751|Fungi	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
LZS2_k127_5171736_0	1191523.MROS_2370	4.034e-115	390.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
LZS2_k127_5178442_0	700598.Niako_1874	4.244e-27	124.0	COG1503@1|root,COG1503@2|Bacteria,4NHF3@976|Bacteroidetes,1IQW9@117747|Sphingobacteriia	976|Bacteroidetes	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5178442_1	1173028.ANKO01000089_gene3665	1.839e-08	62.0	COG1413@1|root,COG1413@2|Bacteria,1G7GF@1117|Cyanobacteria,1HDZM@1150|Oscillatoriales	1117|Cyanobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_5178471_0	926561.KB900623_gene1113	5.736e-103	356.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WA6I@53433|Halanaerobiales	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
LZS2_k127_5178471_2	198094.BA_1928	5.735e-50	198.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS2_k127_5178471_1	383372.Rcas_4299	8.874e-99	331.0	COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS2_k127_5180994_0	1197477.IA57_10225	2.485e-07	59.0	COG3911@1|root,COG3911@2|Bacteria,4NNT6@976|Bacteroidetes,1I25D@117743|Flavobacteriia	976|Bacteroidetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
LZS2_k127_5186258_0	443143.GM18_2435	4.667e-140	462.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,43SA4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283,ko:K03609	-	-	-	-	ko00000,ko02035,ko02044,ko03036,ko04812	-	-	-	CbiA,FHA,T2SSE
LZS2_k127_5186258_2	1051646.VITU9109_20429	0.0008814	51.0	COG0455@1|root,COG0455@2|Bacteria,1N0ZE@1224|Proteobacteria,1S0ZM@1236|Gammaproteobacteria,1Y287@135623|Vibrionales	135623|Vibrionales	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CbiA
LZS2_k127_5186258_1	404589.Anae109_3969	5.3e-06	58.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,42S07@68525|delta/epsilon subdivisions,2WNR0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	TIGRFAM Flp pilus assembly protein CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ChapFlgA,RcpC,SAF
LZS2_k127_5188694_0	246194.CHY_0334	5.167e-274	870.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,42ET0@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
LZS2_k127_5188694_1	103690.17132289	8.222e-54	198.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1HM2J@1161|Nostocales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
LZS2_k127_520007_6	1385935.N836_33660	6.627e-14	71.0	COG0093@1|root,COG0093@2|Bacteria,1G5R9@1117|Cyanobacteria,1HB0B@1150|Oscillatoriales	1117|Cyanobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
LZS2_k127_520007_5	113355.CM001775_gene4097	7.696e-25	106.0	COG0186@1|root,COG0186@2|Bacteria,1G7Q4@1117|Cyanobacteria	1117|Cyanobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
LZS2_k127_520007_7	1125863.JAFN01000001_gene3303	3.511e-09	60.0	COG0255@1|root,COG0255@2|Bacteria,1Q1R3@1224|Proteobacteria,42WYX@68525|delta/epsilon subdivisions,2WSTS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
LZS2_k127_520007_2	865861.AZSU01000001_gene28	4.639e-58	204.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,36E4K@31979|Clostridiaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
LZS2_k127_520007_1	395961.Cyan7425_1298	1.521e-75	261.0	COG0092@1|root,COG0092@2|Bacteria,1G01D@1117|Cyanobacteria,3KFMQ@43988|Cyanothece	1117|Cyanobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rps3	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
LZS2_k127_520007_4	435830.HMPREF0045_01540	1.05e-25	109.0	COG0091@1|root,COG0091@2|Bacteria,2ISS2@201174|Actinobacteria,4D7YF@85005|Actinomycetales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
LZS2_k127_520007_3	443254.Marpi_0876	1.719e-41	154.0	COG0185@1|root,COG0185@2|Bacteria,2GD34@200918|Thermotogae	200918|Thermotogae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
LZS2_k127_520007_0	525904.Tter_0718	5.049e-95	314.0	COG0090@1|root,COG0090@2|Bacteria,2NNR3@2323|unclassified Bacteria	2|Bacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
LZS2_k127_5207116_0	1304284.L21TH_1567	2.904e-106	359.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,2494X@186801|Clostridia,36WTS@31979|Clostridiaceae	186801|Clostridia	P	COG1055 Na H antiporter NhaD and related arsenite permeases	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
LZS2_k127_5207116_2	1499685.CCFJ01000041_gene1167	1.85e-38	162.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli,1ZBK1@1386|Bacillus	91061|Bacilli	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS2_k127_5207116_3	658187.LDG_7519	2.287e-34	150.0	COG4974@1|root,COG4974@2|Bacteria,1R6F9@1224|Proteobacteria,1S0TK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Type 1 fimbriae regulatory protein	fimB	-	-	ko:K07357	-	-	-	-	ko00000	-	-	-	Phage_integrase
LZS2_k127_5207116_4	666685.R2APBS1_3822	5.418e-09	61.0	COG2906@1|root,COG2906@2|Bacteria,1QBPT@1224|Proteobacteria,1T79S@1236|Gammaproteobacteria,1X8ZZ@135614|Xanthomonadales	135614|Xanthomonadales	P	Bacterioferritin-associated ferredoxin	-	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
LZS2_k127_5207116_1	485913.Krac_4426	2.271e-40	156.0	COG2030@1|root,COG2030@2|Bacteria,2G6Y9@200795|Chloroflexi	200795|Chloroflexi	I	MaoC domain protein dehydratase	-	-	2.3.1.19,4.2.1.55	ko:K00634,ko:K17865	ko00630,ko00650,ko01100,ko01120,ko01200,map00630,map00650,map01100,map01120,map01200	M00373	R01174,R03027	RC00004,RC00831,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas,PTA_PTB
LZS2_k127_521599_0	1210884.HG799463_gene10144	1.366e-37	155.0	28HEJ@1|root,2Z7QZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4185,DUF5005
LZS2_k127_521599_2	98439.AJLL01000023_gene862	6.851e-14	83.0	COG1413@1|root,COG1413@2|Bacteria,1G511@1117|Cyanobacteria,1JJSP@1189|Stigonemataceae	1117|Cyanobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
LZS2_k127_521599_1	42256.RradSPS_1149	4.646e-14	80.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS2_k127_522019_0	1173021.ALWA01000020_gene154	5.232e-207	670.0	COG4581@1|root,COG4581@2|Bacteria,1G1R1@1117|Cyanobacteria	1117|Cyanobacteria	L	Superfamily II RNA helicase	ski2	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,Helicase_C
LZS2_k127_5224720_0	517418.Ctha_2453	1.119e-313	977.0	COG1048@1|root,COG1048@2|Bacteria,1FF0B@1090|Chlorobi	1090|Chlorobi	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
LZS2_k127_5224720_1	118168.MC7420_8054	1.79e-05	53.0	COG0457@1|root,COG0457@2|Bacteria,1G0N0@1117|Cyanobacteria,1HEV3@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_5235052_1	1242864.D187_010069	1.767e-51	205.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
LZS2_k127_5235052_0	743720.Psefu_4431	2.864e-64	226.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria,1YXZM@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Cytokinin riboside 5'-monophosphate phosphoribohydrolase	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
LZS2_k127_5235052_2	1144275.COCOR_03380	1.082e-06	61.0	COG5276@1|root,COG5276@2|Bacteria,1Q34V@1224|Proteobacteria,438VJ@68525|delta/epsilon subdivisions,2X41A@28221|Deltaproteobacteria,2YXWY@29|Myxococcales	28221|Deltaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
LZS2_k127_5237710_0	1249627.D779_2281	8.832e-55	201.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,1RYT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	N-formylglutamate amidohydrolase	hutG	-	3.5.1.68,3.5.3.8	ko:K01458,ko:K01479	ko00340,ko00630,ko01100,map00340,map00630,map01100	M00045	R00525,R02285	RC00165,RC00221,RC00323,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
LZS2_k127_5239378_0	1242864.D187_010069	3.25e-53	201.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
LZS2_k127_5244676_1	751945.Theos_0451	0.00054	51.0	COG1752@1|root,COG1752@2|Bacteria,1WI5Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS2_k127_5244676_0	5911.EAR87128	1.399e-07	64.0	COG0457@1|root,KOG0198@1|root,KOG0198@2759|Eukaryota,KOG1840@2759|Eukaryota	2759|Eukaryota	C	determination of stomach left/right asymmetry	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8
LZS2_k127_5261308_2	590998.Celf_0175	5.686e-32	130.0	28PCS@1|root,2ZC50@2|Bacteria,2GITP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5261308_1	264732.Moth_0624	1.671e-108	364.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,42FCG@68295|Thermoanaerobacterales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_5261308_3	525909.Afer_1918	1.177e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CMZF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	sigR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_5261308_4	449447.MAE_62730	1.455e-18	94.0	COG1219@1|root,COG1219@2|Bacteria,1G04H@1117|Cyanobacteria	1117|Cyanobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
LZS2_k127_5261308_0	682795.AciX8_3010	1.2e-121	398.0	COG0657@1|root,COG0657@2|Bacteria,3Y73T@57723|Acidobacteria,2JM3K@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
LZS2_k127_5272110_2	316274.Haur_3424	5.539e-33	141.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi,3751W@32061|Chloroflexia	32061|Chloroflexia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS2_k127_5272110_0	330214.NIDE3103	2.159e-94	324.0	COG1250@1|root,COG1250@2|Bacteria,3J1F9@40117|Nitrospirae	40117|Nitrospirae	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3	ko:K00074,ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R01976,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R05576,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH_N
LZS2_k127_5272110_1	1267580.AF6_1998	5.986e-51	191.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli,21WAU@150247|Anoxybacillus	91061|Bacilli	E	C-terminus of AA_permease	yfnA	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS2_k127_5301234_0	1267533.KB906737_gene1784	2.716e-169	556.0	COG0366@1|root,COG0366@2|Bacteria,3Y2IV@57723|Acidobacteria,2JHKG@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_N
LZS2_k127_5301234_1	1242864.D187_006042	6.244e-55	214.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase,TonB_C
LZS2_k127_5313242_0	269799.Gmet_1369	8.135e-34	139.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria,43SI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
LZS2_k127_5313242_1	1267535.KB906767_gene5318	1.793e-07	57.0	2ESQI@1|root,33K8Z@2|Bacteria,3Y8KQ@57723|Acidobacteria,2JNJQ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5319236_1	1437448.AZRT01000008_gene4853	4.723e-22	104.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,2U1UX@28211|Alphaproteobacteria,1J3GV@118882|Brucellaceae	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
LZS2_k127_5319236_0	338963.Pcar_3086	1.856e-46	177.0	COG2197@1|root,COG2197@2|Bacteria,1PHR7@1224|Proteobacteria,42UJB@68525|delta/epsilon subdivisions,2WQPN@28221|Deltaproteobacteria,43SQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_5320331_0	349161.Dred_0189	2.36e-227	717.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,2607A@186807|Peptococcaceae	186801|Clostridia	J	PFAM tRNA synthetases class I (E and Q), catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
LZS2_k127_5320331_1	1545915.JROG01000007_gene3144	0.0003328	44.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,2K0XR@204457|Sphingomonadales	204457|Sphingomonadales	E	Cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_5327734_3	1396141.BATP01000003_gene4947	4.003e-18	93.0	COG3429@1|root,COG3429@2|Bacteria,46V8B@74201|Verrucomicrobia,2IUBI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
LZS2_k127_5327734_0	321332.CYB_1985	2.953e-165	537.0	COG0364@1|root,COG0364@2|Bacteria,1G0K9@1117|Cyanobacteria,1GYST@1129|Synechococcus	1117|Cyanobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
LZS2_k127_5327734_1	1123251.ATWM01000003_gene1227	7.004e-123	411.0	COG0277@1|root,COG0277@2|Bacteria,2GJ33@201174|Actinobacteria,4FFAM@85021|Intrasporangiaceae	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
LZS2_k127_5327734_2	42256.RradSPS_1184	4.967e-70	246.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,4CPUN@84995|Rubrobacteria	84995|Rubrobacteria	L	helicase superfamily c-terminal domain	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C
LZS2_k127_5327763_1	1173024.KI912149_gene5297	2.737e-24	105.0	COG2335@1|root,COG2335@2|Bacteria,1G5TY@1117|Cyanobacteria,1JIQD@1189|Stigonemataceae	1117|Cyanobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
LZS2_k127_5327763_2	1408321.JNJD01000009_gene1720	9.133e-18	89.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,27NQU@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_5327763_0	158190.SpiGrapes_3022	5.146e-93	343.0	COG0465@1|root,COG0465@2|Bacteria,2J58Y@203691|Spirochaetes	203691|Spirochaetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_534016_0	1301100.HG529272_gene1717	8.693e-16	92.0	COG0457@1|root,COG0457@2|Bacteria,1UYZH@1239|Firmicutes,24BU9@186801|Clostridia,36F2E@31979|Clostridiaceae	186801|Clostridia	S	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
LZS2_k127_534016_1	317936.Nos7107_1433	0.0001016	55.0	COG0457@1|root,COG0457@2|Bacteria,1G07G@1117|Cyanobacteria,1HIWQ@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8
LZS2_k127_534386_0	866775.HMPREF9243_0834	1.355e-70	252.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,27DNJ@186827|Aerococcaceae	91061|Bacilli	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
LZS2_k127_5346980_2	1316927.ATKI01000143_gene4096	9.689e-07	59.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1S12M@1236|Gammaproteobacteria,1YNYV@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
LZS2_k127_5346980_0	1120985.AUMI01000004_gene1349	1.558e-94	323.0	COG2984@1|root,COG4251@1|root,COG2984@2|Bacteria,COG4251@2|Bacteria,1UMZ2@1239|Firmicutes,4H9I5@909932|Negativicutes	1239|Firmicutes	T	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,PAS
LZS2_k127_5346980_1	292415.Tbd_1192	4.321e-46	170.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria,1KT24@119069|Hydrogenophilales	119069|Hydrogenophilales	T	cheY-homologous receiver domain	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
LZS2_k127_5350977_1	676032.FN3523_0038	8.571e-69	239.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,46077@72273|Thiotrichales	72273|Thiotrichales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS2_k127_5350977_2	573569.F7308_0048	5.732e-60	213.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,45ZQ2@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
LZS2_k127_5350977_0	573569.F7308_0049	2.891e-184	587.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,4601D@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
LZS2_k127_5350977_3	316274.Haur_4444	1.964e-19	89.0	COG0119@1|root,COG0119@2|Bacteria,2G5KT@200795|Chloroflexi,3758Q@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
LZS2_k127_5352474_1	118168.MC7420_7720	1.591e-59	225.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria,1H88B@1150|Oscillatoriales	1117|Cyanobacteria	M	Lipid A core - O-antigen ligase	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
LZS2_k127_5352474_3	1183438.GKIL_2117	1.06e-19	94.0	29BP0@1|root,2ZYMB@2|Bacteria,1G5R6@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4330
LZS2_k127_5352474_0	388467.A19Y_2302	1.806e-70	261.0	COG2870@1|root,COG2870@2|Bacteria,1G2IU@1117|Cyanobacteria,1H898@1150|Oscillatoriales	1117|Cyanobacteria	M	ADP-heptose synthase, bifunctional sugar kinase adenylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS2_k127_5352474_2	926559.JoomaDRAFT_3316	8.658e-31	132.0	COG0730@1|root,COG0730@2|Bacteria,4NGP8@976|Bacteroidetes,1HXW1@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_5366747_4	555088.DealDRAFT_0284	0.0004845	45.0	COG0864@1|root,COG0864@2|Bacteria,1U4DI@1239|Firmicutes,25NZ0@186801|Clostridia,42K85@68298|Syntrophomonadaceae	186801|Clostridia	K	PFAM CopG domain protein DNA-binding domain protein	-	-	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
LZS2_k127_5366747_2	251221.35210700	1.816e-89	301.0	COG0708@1|root,COG0708@2|Bacteria,1G29X@1117|Cyanobacteria	1117|Cyanobacteria	L	Exodeoxyribonuclease iii	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
LZS2_k127_5366747_0	886293.Sinac_3404	7.114e-248	780.0	COG1960@1|root,COG1960@2|Bacteria,2IXZJ@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_5366747_3	1242864.D187_002185	2.676e-15	85.0	COG5316@1|root,COG5316@2|Bacteria,1NWFX@1224|Proteobacteria,42NSK@68525|delta/epsilon subdivisions,2WMAZ@28221|Deltaproteobacteria,2YUUF@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
LZS2_k127_5366747_1	716544.wcw_0742	4.463e-95	321.0	COG1090@1|root,COG1090@2|Bacteria,2JFV6@204428|Chlamydiae	204428|Chlamydiae	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
LZS2_k127_5403340_1	670487.Ocepr_0126	2.708e-08	66.0	COG2804@1|root,COG2804@2|Bacteria,1WIW9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilF	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
LZS2_k127_5403340_0	311424.DhcVS_827	7.464e-19	88.0	COG0605@1|root,COG0605@2|Bacteria,2G5Q9@200795|Chloroflexi,34D0I@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Iron/manganese superoxide dismutases, C-terminal domain	sod	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C
LZS2_k127_540501_0	1380355.JNIJ01000007_gene3273	3.982e-30	126.0	COG1670@1|root,COG1670@2|Bacteria,1RF8W@1224|Proteobacteria,2U707@28211|Alphaproteobacteria,3JZ10@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
LZS2_k127_540501_1	1122223.KB890688_gene1843	0.0004865	51.0	COG0589@1|root,COG0589@2|Bacteria,1WMQ9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_540814_0	926569.ANT_15160	2.535e-39	164.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
LZS2_k127_540814_1	225400.XP_006770281.1	3.222e-12	76.0	COG0457@1|root,KOG1840@2759|Eukaryota,38C2F@33154|Opisthokonta,3BDX7@33208|Metazoa,3CWWE@33213|Bilateria,484B4@7711|Chordata,494XP@7742|Vertebrata,3J5Y6@40674|Mammalia,4KRMZ@9397|Chiroptera	33208|Metazoa	Z	Tetratricopeptide repeat	NPHP3	GO:0001655,GO:0001822,GO:0001889,GO:0001894,GO:0001895,GO:0001947,GO:0002009,GO:0003007,GO:0003143,GO:0003205,GO:0003230,GO:0003279,GO:0003283,GO:0003341,GO:0003351,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005929,GO:0006629,GO:0006928,GO:0006996,GO:0007017,GO:0007018,GO:0007163,GO:0007275,GO:0007368,GO:0007369,GO:0007389,GO:0007507,GO:0008150,GO:0008152,GO:0009653,GO:0009790,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0016043,GO:0022603,GO:0022607,GO:0023051,GO:0023057,GO:0030030,GO:0030031,GO:0030111,GO:0030178,GO:0030198,GO:0030323,GO:0030324,GO:0031016,GO:0032501,GO:0032502,GO:0035050,GO:0035239,GO:0035295,GO:0035469,GO:0042592,GO:0042995,GO:0043062,GO:0043226,GO:0044085,GO:0044238,GO:0044422,GO:0044424,GO:0044441,GO:0044444,GO:0044463,GO:0044464,GO:0044782,GO:0045494,GO:0045595,GO:0045596,GO:0045995,GO:0048496,GO:0048513,GO:0048519,GO:0048523,GO:0048562,GO:0048565,GO:0048568,GO:0048583,GO:0048585,GO:0048598,GO:0048729,GO:0048731,GO:0048732,GO:0048856,GO:0048871,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051239,GO:0051960,GO:0055123,GO:0060026,GO:0060027,GO:0060249,GO:0060271,GO:0060287,GO:0060429,GO:0060541,GO:0060562,GO:0060828,GO:0060993,GO:0061008,GO:0061371,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071840,GO:0071907,GO:0071908,GO:0071909,GO:0071910,GO:0072001,GO:0072189,GO:0072359,GO:0090090,GO:0090175,GO:0090178,GO:0097543,GO:0097546,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:1905276,GO:1905330,GO:1905515,GO:2000026,GO:2000027,GO:2000050,GO:2000095,GO:2000167	-	ko:K19360	-	-	-	-	ko00000,ko03036	-	-	-	NACHT,TPR_12,TPR_7,TPR_8
LZS2_k127_5411056_1	1472716.KBK24_0109040	2.007e-06	59.0	COG4655@1|root,COG4655@2|Bacteria,1PIEK@1224|Proteobacteria,2W728@28216|Betaproteobacteria,1K622@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative Tad-like Flp pilus-assembly	-	-	-	-	-	-	-	-	-	-	-	-	Tad
LZS2_k127_5411056_0	351627.Csac_2076	2.384e-53	209.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5424432_0	643473.KB235930_gene2469	7.221e-36	148.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1G027@1117|Cyanobacteria,1HKPC@1161|Nostocales	1117|Cyanobacteria	T	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,Trans_reg_C
LZS2_k127_5424989_3	671143.DAMO_2637	5.097e-07	53.0	COG0402@1|root,COG0402@2|Bacteria,2NPE6@2323|unclassified Bacteria	2|Bacteria	F	Amidohydrolase family	guaD	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0016814,GO:0018756,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3170,iECED1_1282.ECED1_3343,iECIAI1_1343.ECIAI1_3003,iECSE_1348.ECSE_3147	Amidohydro_1
LZS2_k127_5424989_2	56780.SYN_02450	4.532e-44	167.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42SNI@68525|delta/epsilon subdivisions,2WPFN@28221|Deltaproteobacteria,2MRUX@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
LZS2_k127_5424989_1	517418.Ctha_1581	6.443e-79	284.0	COG0612@1|root,COG0612@2|Bacteria,1FEWA@1090|Chlorobi	1090|Chlorobi	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_5424989_0	1122179.KB890458_gene744	3.597e-86	302.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_5436009_0	1304880.JAGB01000001_gene680	3.212e-34	140.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5436302_1	411465.PEPMIC_01605	1.095e-21	101.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,22H8I@1570339|Peptoniphilaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS2_k127_5436302_0	402777.KB235903_gene1591	1.03e-100	338.0	COG0714@1|root,COG0714@2|Bacteria,1G1CG@1117|Cyanobacteria,1H70V@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_5436302_2	1499968.TCA2_2064	1.242e-12	80.0	COG1721@1|root,COG1721@2|Bacteria,1TUWF@1239|Firmicutes,4HDRE@91061|Bacilli,26QTE@186822|Paenibacillaceae	91061|Bacilli	S	conserved protein (some members contain a von willebrand factor type A (vWA) domain)	yeaD	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS2_k127_5447537_0	574087.Acear_0723	5.359e-194	623.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3WA7Y@53433|Halanaerobiales	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
LZS2_k127_5447537_1	580340.Tlie_1250	8.419e-146	485.0	COG0480@1|root,COG0480@2|Bacteria,3TA2B@508458|Synergistetes	508458|Synergistetes	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS2_k127_5448722_0	204669.Acid345_0598	1.037e-91	308.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
LZS2_k127_5448722_1	272630.MexAM1_META1p2494	6.571e-12	74.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TS3K@28211|Alphaproteobacteria,1JRKY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS2_k127_5455472_1	935840.JAEQ01000006_gene2609	3.949e-141	456.0	2DMX8@1|root,32U7B@2|Bacteria,1MZTG@1224|Proteobacteria,2UPH9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	SacI restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_SacI
LZS2_k127_5455472_2	935840.JAEQ01000006_gene2610	6.593e-27	111.0	2DS1C@1|root,33E47@2|Bacteria,1Q8HP@1224|Proteobacteria,2UW9N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
LZS2_k127_5455472_0	935840.JAEQ01000006_gene2611	6.692e-215	673.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2TUCJ@28211|Alphaproteobacteria,43K13@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
LZS2_k127_5455472_3	929713.NIASO_06665	1.717e-10	63.0	COG3183@1|root,COG3183@2|Bacteria,4NVZE@976|Bacteroidetes,1IYYI@117747|Sphingobacteriia	976|Bacteroidetes	V	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
LZS2_k127_5461960_2	1210884.HG799462_gene7846	2.278e-07	55.0	COG3011@1|root,COG3011@2|Bacteria,2J1CZ@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
LZS2_k127_5461960_1	234267.Acid_5820	1.669e-79	287.0	COG0312@1|root,COG0312@2|Bacteria,3Y686@57723|Acidobacteria	57723|Acidobacteria	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
LZS2_k127_5461960_0	1198114.AciX9_0691	4.168e-104	349.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria,2JKR9@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
LZS2_k127_5462430_2	1155714.KB891995_gene4147	9.054e-07	60.0	COG0515@1|root,COG0515@2|Bacteria,2GM1F@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_5462430_1	1254432.SCE1572_07800	1.856e-58	226.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_5462430_0	1173026.Glo7428_0872	5.379e-86	291.0	COG1190@1|root,COG1190@2|Bacteria,1G0SA@1117|Cyanobacteria	1117|Cyanobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN678.lysS	KTSC,tRNA-synt_2,tRNA_anti-codon
LZS2_k127_5467509_0	1158345.JNLL01000001_gene705	1.32e-36	157.0	COG5001@1|root,COG5001@2|Bacteria,2G441@200783|Aquificae	200783|Aquificae	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
LZS2_k127_547201_0	1123508.JH636439_gene528	4.575e-27	128.0	COG2070@1|root,COG3321@1|root,COG2070@2|Bacteria,COG3321@2|Bacteria,2IY7E@203682|Planctomycetes	203682|Planctomycetes	IQ	Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,ketoacyl-synt
LZS2_k127_5483244_3	661478.OP10G_3754	7.016e-40	153.0	COG0315@1|root,COG0315@2|Bacteria	2|Bacteria	H	cyclic pyranopterin monophosphate synthase activity	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
LZS2_k127_5483244_1	4641.GSMUA_Achr1P19680_001	2.455e-93	317.0	COG2896@1|root,KOG2876@2759|Eukaryota,37HYZ@33090|Viridiplantae,3GGVM@35493|Streptophyta,3KMYM@4447|Liliopsida	35493|Streptophyta	H	Molybdenum Cofactor Synthesis C	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009536,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
LZS2_k127_5483244_2	1162668.LFE_0473	2.967e-40	154.0	COG0314@1|root,COG0314@2|Bacteria,3J1AN@40117|Nitrospirae	40117|Nitrospirae	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
LZS2_k127_5483244_4	382464.ABSI01000011_gene3136	1.034e-17	86.0	COG1977@1|root,COG1977@2|Bacteria,46WS8@74201|Verrucomicrobia	74201|Verrucomicrobia	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS2_k127_5483244_5	443143.GM18_1659	7.569e-06	58.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_3,DUF4347,HemolysinCabind,Phosphoesterase,VCBS,fn3
LZS2_k127_5483244_0	118173.KB235914_gene792	2.259e-227	722.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
LZS2_k127_5488643_0	1042877.GQS_09115	9.895e-17	93.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota,242SB@183968|Thermococci	183968|Thermococci	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_5488643_1	243233.MCA2477	5.319e-11	63.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1XE8M@135618|Methylococcales	135618|Methylococcales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	DsbC,Thioredox_DsbH
LZS2_k127_5500506_0	240292.Ava_1628	1.132e-40	163.0	COG0642@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,dCache_1
LZS2_k127_5521619_0	861299.J421_6266	2.051e-169	543.0	COG2211@1|root,COG2211@2|Bacteria,1ZUJ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	MFS/sugar transport protein	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
LZS2_k127_5521619_3	1123242.JH636434_gene5321	1.984e-25	113.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
LZS2_k127_5521619_2	639282.DEFDS_2129	4.966e-31	129.0	COG2716@1|root,COG2716@2|Bacteria,2GFPG@200930|Deferribacteres	200930|Deferribacteres	E	ACT domain	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT,ACT_6
LZS2_k127_5521619_1	338963.Pcar_2534	1.299e-40	156.0	COG0242@1|root,COG0242@2|Bacteria,1QM3A@1224|Proteobacteria,42RV0@68525|delta/epsilon subdivisions,2WNJB@28221|Deltaproteobacteria,43SIG@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Polypeptide deformylase	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
LZS2_k127_5521619_4	1068978.AMETH_2656	2.963e-17	93.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4E37Q@85010|Pseudonocardiales	201174|Actinobacteria	Q	Poly(3-hydroxybutyrate) depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
LZS2_k127_5523017_2	1449126.JQKL01000035_gene2175	5.947e-19	91.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,268SR@186813|unclassified Clostridiales	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
LZS2_k127_5523017_0	1140.Synpcc7942_1525	5.622e-253	795.0	COG1217@1|root,COG1217@2|Bacteria,1G0FW@1117|Cyanobacteria,1GZ9I@1129|Synechococcus	1117|Cyanobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
LZS2_k127_5523017_1	1169144.KB910924_gene424	2.475e-44	184.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5526237_0	515635.Dtur_1789	2.941e-49	194.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria	2|Bacteria	T	Chase2 domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
LZS2_k127_5526237_1	515635.Dtur_1789	3.609e-48	191.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria	2|Bacteria	T	Chase2 domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
LZS2_k127_5526237_2	1408473.JHXO01000005_gene1613	9.828e-26	115.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes	976|Bacteroidetes	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS2_k127_5526601_0	997346.HMPREF9374_1431	1.728e-24	108.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,27C1C@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosomal silencing factor during starvation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
LZS2_k127_5526601_1	864702.OsccyDRAFT_2257	1.743e-23	102.0	COG0776@1|root,COG0776@2|Bacteria,1G8Y4@1117|Cyanobacteria,1HFWP@1150|Oscillatoriales	1117|Cyanobacteria	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
LZS2_k127_5526601_2	240016.ABIZ01000001_gene3824	0.0003293	52.0	COG0457@1|root,COG0457@2|Bacteria	240016.ABIZ01000001_gene3824|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5534528_3	1242864.D187_006841	3.193e-07	56.0	2DI9M@1|root,302FW@2|Bacteria,1PVCY@1224|Proteobacteria,433WW@68525|delta/epsilon subdivisions,2X8YG@28221|Deltaproteobacteria,2YXHF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5534528_1	521000.PROVRETT_05456	4.078e-23	114.0	COG1661@1|root,COG1661@2|Bacteria,1RIME@1224|Proteobacteria,1S71M@1236|Gammaproteobacteria,3Z95J@586|Providencia	1236|Gammaproteobacteria	S	UDP-N-acetylglucosamine pyrophosphorylase K04042	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
LZS2_k127_5534528_2	685727.REQ_42200	1.455e-17	96.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria,4FW0U@85025|Nocardiaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	ytpA	GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
LZS2_k127_5534528_0	940282.CADQ01000066_gene644	3.912e-31	129.0	COG0607@1|root,COG0607@2|Bacteria,1RDIR@1224|Proteobacteria,2U820@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Protein of unknown function (DUF2892)	ygaP	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
LZS2_k127_5537030_0	32057.KB217478_gene1658	1.596e-34	152.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HKZW@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
LZS2_k127_5541725_2	879308.HMPREF9130_0157	9.115e-14	76.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,22GU1@1570339|Peptoniphilaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	nikA	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_5541725_1	1123507.ATVQ01000001_gene1935	2.165e-19	96.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,1W97Y@1268|Micrococcaceae	201174|Actinobacteria	S	Putative single-stranded nucleic acids-binding domain	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	KH_4,R3H
LZS2_k127_5541725_0	580340.Tlie_0712	2.773e-21	107.0	COG0706@1|root,COG0706@2|Bacteria,3T9Q5@508458|Synergistetes	508458|Synergistetes	U	Membrane protein insertase, YidC Oxa1 family	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
LZS2_k127_5544473_1	620914.JH621250_gene2257	2.114e-43	163.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,4NHA0@976|Bacteroidetes,1HZ9E@117743|Flavobacteriia,2YGY5@290174|Aquimarina	976|Bacteroidetes	H	MoaC family	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoaC
LZS2_k127_5544473_0	1453505.JASY01000007_gene1121	8.028e-75	265.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes,1HXGQ@117743|Flavobacteriia,2NTSQ@237|Flavobacterium	976|Bacteroidetes	H	molybdenum cofactor	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS2_k127_5547485_0	118163.Ple7327_4006	2.002e-134	447.0	COG0086@1|root,COG0086@2|Bacteria,1G08B@1117|Cyanobacteria,3VJ6B@52604|Pleurocapsales	1117|Cyanobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC2	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
LZS2_k127_5547485_3	156578.ATW7_16645	0.0002554	50.0	COG1305@1|root,COG1305@2|Bacteria,1R5Q7@1224|Proteobacteria,1RPH2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG1305 Transglutaminase-like enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
LZS2_k127_5547485_2	349966.DJ58_3798	1.617e-16	80.0	COG4226@1|root,COG4226@2|Bacteria,1MZYR@1224|Proteobacteria,1SAHX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein encoded in hypervariable junctions of pilus gene clusters	hicB	-	-	-	-	-	-	-	-	-	-	-	HicB
LZS2_k127_5547485_1	146922.JOFU01000048_gene5024	3.415e-37	157.0	COG4886@1|root,COG4886@2|Bacteria,2GNZ0@201174|Actinobacteria	201174|Actinobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5548968_0	42565.FP66_00900	3.732e-09	62.0	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,1SBUW@1236|Gammaproteobacteria,1XMR6@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5556548_0	1121949.AQXT01000002_gene1166	8.432e-176	556.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,43WMI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
LZS2_k127_5556548_1	65393.PCC7424_0433	7.003e-64	226.0	COG1352@1|root,COG1352@2|Bacteria,1G1W9@1117|Cyanobacteria,3KFQZ@43988|Cyanothece	1117|Cyanobacteria	NT	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80,3.1.1.61	ko:K00575,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheR,CheR_N,PAS,PAS_4,PAS_9
LZS2_k127_5566651_1	383372.Rcas_3394	2.595e-70	254.0	COG1249@1|root,COG1249@2|Bacteria,2G7VE@200795|Chloroflexi	200795|Chloroflexi	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
LZS2_k127_5566651_3	1340493.JNIF01000003_gene2408	9.81e-50	183.0	COG1778@1|root,COG1778@2|Bacteria,3Y5BY@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
LZS2_k127_5566651_2	639282.DEFDS_0024	6.756e-64	224.0	COG1100@1|root,COG1100@2|Bacteria,2GEYH@200930|Deferribacteres	200930|Deferribacteres	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
LZS2_k127_5566651_4	309799.DICTH_1557	3.603e-07	63.0	COG0745@1|root,COG0745@2|Bacteria	309799.DICTH_1557|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5566651_0	344747.PM8797T_05265	5.524e-101	332.0	COG1180@1|root,COG1355@1|root,COG2078@1|root,COG1180@2|Bacteria,COG1355@2|Bacteria,COG2078@2|Bacteria,2IYWA@203682|Planctomycetes	203682|Planctomycetes	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS2_k127_559080_0	32057.KB217478_gene5161	6.823e-45	172.0	COG2197@1|root,COG2197@2|Bacteria,1G1P0@1117|Cyanobacteria,1HM6U@1161|Nostocales	1117|Cyanobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_559080_1	324057.Pjdr2_4423	2.664e-29	123.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,26S1K@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
LZS2_k127_559080_3	1079460.ATTQ01000043_gene6074	2.823e-11	68.0	COG4453@1|root,COG4453@2|Bacteria,1MZ3W@1224|Proteobacteria,2UDAM@28211|Alphaproteobacteria,4BH67@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
LZS2_k127_559080_2	251221.35211763	4.051e-29	125.0	COG0454@1|root,COG0456@2|Bacteria,1G7A2@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS2_k127_5591_2	1121472.AQWN01000009_gene355	5.265e-05	51.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,2603X@186807|Peptococcaceae	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
LZS2_k127_5591_0	1173026.Glo7428_2808	4.537e-68	249.0	COG1215@1|root,COG1215@2|Bacteria,1FZYV@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576	2.4.1.336	ko:K19003	ko00561,ko01100,map00561,map01100	-	R02689	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3
LZS2_k127_5591_1	1173025.GEI7407_0575	1.412e-35	147.0	COG0477@1|root,COG2814@2|Bacteria,1G0DP@1117|Cyanobacteria,1H9H2@1150|Oscillatoriales	1117|Cyanobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_5595361_1	251221.35211704	3.822e-14	78.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS2_k127_5595361_0	1380347.JNII01000010_gene2487	1.115e-37	156.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4ERVU@85013|Frankiales	201174|Actinobacteria	F	PFAM Adenosine AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
LZS2_k127_5595361_2	1238184.CM001792_gene2536	1.403e-06	57.0	2DYSU@1|root,34AZ0@2|Bacteria,1VZ25@1239|Firmicutes,4HZDF@91061|Bacilli,23N49@182709|Oceanobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5609196_5	448385.sce6304	4.329e-21	96.0	COG0477@1|root,COG2814@2|Bacteria,1N9NR@1224|Proteobacteria,43BA7@68525|delta/epsilon subdivisions,2WXBD@28221|Deltaproteobacteria,2Z19U@29|Myxococcales	28221|Deltaproteobacteria	EGP	Domain of unknown function (DUF3817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3817
LZS2_k127_5609196_9	1382306.JNIM01000001_gene2372	7.538e-14	84.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	Pkinase,WD40
LZS2_k127_5609196_2	1454004.AW11_00393	5.586e-124	404.0	COG1171@1|root,COG1171@2|Bacteria,1NN0Z@1224|Proteobacteria,2VN4D@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	sdsL	-	4.3.1.17,4.3.1.19	ko:K17989	ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00590,R00996	RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_5609196_3	671143.DAMO_1524	6.862e-61	219.0	COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria	2|Bacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.1.1.199	ko:K03438,ko:K13292	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	LGT
LZS2_k127_5609196_1	195250.CM001776_gene1957	1.666e-128	428.0	COG1066@1|root,COG1066@2|Bacteria,1G0A9@1117|Cyanobacteria,1GZCR@1129|Synechococcus	1117|Cyanobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
LZS2_k127_5609196_0	868595.Desca_2524	1.328e-146	485.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,260I5@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
LZS2_k127_5609196_4	497965.Cyan7822_2113	9.077e-54	216.0	COG0457@1|root,COG0457@2|Bacteria,1G1QI@1117|Cyanobacteria,3KJEK@43988|Cyanothece	1117|Cyanobacteria	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_10,TPR_12,TPR_7
LZS2_k127_5609196_7	1313421.JHBV01000030_gene2141	4.038e-16	93.0	COG2319@1|root,COG4249@1|root,COG2319@2|Bacteria,COG4249@2|Bacteria,4NIFD@976|Bacteroidetes	976|Bacteroidetes	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
LZS2_k127_5609196_8	395961.Cyan7425_3067	4.733e-14	83.0	COG2267@1|root,COG2267@2|Bacteria,1G2EN@1117|Cyanobacteria,3KG8B@43988|Cyanothece	1117|Cyanobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_5609196_6	886882.PPSC2_c0638	2.752e-20	92.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,27248@186822|Paenibacillaceae	91061|Bacilli	L	ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
LZS2_k127_5609941_1	391587.KAOT1_19337	1.648e-25	123.0	COG1807@1|root,COG1807@2|Bacteria,4P0P4@976|Bacteroidetes,1I8CJ@117743|Flavobacteriia	976|Bacteroidetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_5609941_0	1183438.GKIL_3078	2.208e-35	154.0	COG1807@1|root,COG1807@2|Bacteria,1GCPV@1117|Cyanobacteria	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_5616961_1	1267534.KB906759_gene1729	1.032e-109	361.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	2|Bacteria	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
LZS2_k127_5616961_0	1267534.KB906759_gene1728	2.68e-155	512.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1164	PFOR_II,POR,POR_N,Transketolase_C
LZS2_k127_5617222_3	1430440.MGMSRv2_1518	1.514e-11	76.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JPVE@204441|Rhodospirillales	204441|Rhodospirillales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_9,Response_reg
LZS2_k127_5617222_2	545695.TREAZ_2069	1.26e-11	67.0	2BMZV@1|root,32GJU@2|Bacteria,2JAQU@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5617222_1	393305.YE1682	4.988e-37	144.0	COG2503@1|root,COG2503@2|Bacteria,1QUNJ@1224|Proteobacteria	1224|Proteobacteria	S	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
LZS2_k127_5617222_0	1089553.Tph_c14230	1.85e-43	174.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5624086_2	697281.Mahau_0989	3.665e-18	94.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5624086_1	649747.HMPREF0083_03170	7.606e-66	233.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,26RCQ@186822|Paenibacillaceae	91061|Bacilli	L	Hydrolase, tatd	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
LZS2_k127_5624086_0	1303518.CCALI_01855	3.202e-138	454.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	glcD	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iJN746.PP_3745,iLF82_1304.LF82_0831,iNRG857_1313.NRG857_14750	FAD-oxidase_C,FAD_binding_4
LZS2_k127_5629432_0	1173022.Cri9333_2006	5.736e-110	381.0	COG4122@1|root,COG4122@2|Bacteria,1GBCN@1117|Cyanobacteria,1HEQZ@1150|Oscillatoriales	1117|Cyanobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5631156_0	323261.Noc_2141	0.0	1024.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WX0W@135613|Chromatiales	135613|Chromatiales	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
LZS2_k127_5631156_2	472759.Nhal_1155	2.639e-46	179.0	2C6D0@1|root,31F07@2|Bacteria,1RHBN@1224|Proteobacteria,1S7HH@1236|Gammaproteobacteria,1WX2B@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
LZS2_k127_5631156_3	1238184.CM001792_gene3346	3.023e-43	173.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,4HHE1@91061|Bacilli,23J6N@182709|Oceanobacillus	91061|Bacilli	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
LZS2_k127_5631156_1	102232.GLO73106DRAFT_00040100	4.943e-52	199.0	COG4826@1|root,COG4826@2|Bacteria,1G29E@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
LZS2_k127_5631156_4	1075090.GOAMR_50_00520	8.406e-34	142.0	COG0596@1|root,COG0596@2|Bacteria,2IA2Y@201174|Actinobacteria,4GBAQ@85026|Gordoniaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_5631284_1	7955.ENSDARP00000122475	7.92e-05	51.0	COG0308@1|root,KOG1046@2759|Eukaryota,38CFG@33154|Opisthokonta,3BADC@33208|Metazoa,3CW5S@33213|Bilateria,486H0@7711|Chordata,48VUN@7742|Vertebrata,4A251@7898|Actinopterygii	33208|Metazoa	O	Aminopeptidase puromycin sensitive	NPEPPS	GO:0000003,GO:0000209,GO:0000578,GO:0000793,GO:0000922,GO:0001666,GO:0003002,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005819,GO:0005829,GO:0005856,GO:0006464,GO:0006508,GO:0006518,GO:0006807,GO:0006950,GO:0007049,GO:0007275,GO:0007350,GO:0007351,GO:0007389,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008595,GO:0009056,GO:0009628,GO:0009790,GO:0009792,GO:0009798,GO:0009880,GO:0009948,GO:0009952,GO:0009987,GO:0010564,GO:0010720,GO:0015630,GO:0016567,GO:0016787,GO:0019538,GO:0022402,GO:0022414,GO:0030588,GO:0030590,GO:0032446,GO:0032501,GO:0032502,GO:0033218,GO:0033554,GO:0034641,GO:0035282,GO:0036211,GO:0036293,GO:0036294,GO:0042221,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043603,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044771,GO:0045595,GO:0045597,GO:0046662,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050896,GO:0051094,GO:0051179,GO:0051235,GO:0051239,GO:0051240,GO:0051321,GO:0051445,GO:0051640,GO:0051641,GO:0051642,GO:0051651,GO:0051657,GO:0051661,GO:0051716,GO:0051726,GO:0060281,GO:0060282,GO:0060284,GO:0061842,GO:0065007,GO:0065008,GO:0070006,GO:0070011,GO:0070482,GO:0070647,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0072686,GO:0097431,GO:0140096,GO:1900193,GO:1900195,GO:1901564,GO:1901565,GO:1901575,GO:1903046,GO:1903429,GO:1903431,GO:1903538,GO:1905879,GO:1905881,GO:1990947,GO:2000241,GO:2000243	-	ko:K08776	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
LZS2_k127_5631284_0	504728.K649_01155	1.911e-190	605.0	COG0366@1|root,COG0366@2|Bacteria,1WI07@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM alpha amylase, catalytic	-	-	3.2.1.1,3.2.1.20	ko:K01176,ko:K01187	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00028,R00801,R00802,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459,Malt_amylase_C
LZS2_k127_5644377_4	1120983.KB894571_gene2442	1.179e-33	137.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,1JPAK@119043|Rhodobiaceae	28211|Alphaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS2_k127_5644377_2	1121035.AUCH01000005_gene11	9.737e-40	171.0	COG2304@1|root,COG2304@2|Bacteria,1MX4C@1224|Proteobacteria	1224|Proteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
LZS2_k127_5644377_6	1408433.JHXV01000001_gene747	2.914e-19	90.0	COG2329@1|root,COG2329@2|Bacteria,4PAZI@976|Bacteroidetes,1IG6J@117743|Flavobacteriia,2PC22@246874|Cryomorphaceae	976|Bacteroidetes	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5644377_1	1408428.JNJP01000005_gene23	7.425e-56	203.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,42KZX@68525|delta/epsilon subdivisions,2WU4V@28221|Deltaproteobacteria,2MAIK@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_5644377_3	1396141.BATP01000007_gene5587	8.833e-37	144.0	COG2259@1|root,COG2259@2|Bacteria,46VRD@74201|Verrucomicrobia,2IVXH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
LZS2_k127_5644377_7	771875.Ferpe_0714	2.472e-14	86.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
LZS2_k127_5644377_0	404589.Anae109_0478	7.717e-168	545.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2YZII@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
LZS2_k127_5644377_5	1120965.AUBV01000015_gene1119	2.869e-29	125.0	COG3222@1|root,COG3222@2|Bacteria,4NM7F@976|Bacteroidetes,47PF2@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
LZS2_k127_56473_1	1173022.Cri9333_3515	2.821e-75	255.0	COG1403@1|root,COG1403@2|Bacteria,1G180@1117|Cyanobacteria,1H8A9@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
LZS2_k127_56473_0	525367.HMPREF0556_11203	3.134e-164	548.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,26J6V@186820|Listeriaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
LZS2_k127_5649286_0	404589.Anae109_1904	4.148e-09	57.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
LZS2_k127_5650162_2	477974.Daud_1318	3.375e-16	84.0	COG3172@1|root,COG3172@2|Bacteria,1VQ43@1239|Firmicutes,251WS@186801|Clostridia,265QW@186807|Peptococcaceae	186801|Clostridia	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
LZS2_k127_5650162_0	452637.Oter_2033	5.487e-101	347.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
LZS2_k127_5650162_3	452637.Oter_2033	1.017e-13	81.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
LZS2_k127_5650162_4	1499689.CCNN01000007_gene2220	0.0005313	51.0	COG1585@1|root,COG1585@2|Bacteria,1VD3E@1239|Firmicutes,24H38@186801|Clostridia,36IDP@31979|Clostridiaceae	186801|Clostridia	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449,NfeD
LZS2_k127_5650162_1	1121423.JONT01000008_gene800	3.345e-80	280.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,260EB@186807|Peptococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
LZS2_k127_5650727_0	118173.KB235914_gene4129	5.731e-106	348.0	COG0516@1|root,COG0516@2|Bacteria,1G1MX@1117|Cyanobacteria,1H94E@1150|Oscillatoriales	1117|Cyanobacteria	F	IMP dehydrogenase GMP reductase	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
LZS2_k127_5657610_0	383372.Rcas_2847	7.904e-120	392.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS2_k127_5657610_1	330214.NIDE1044	3.61e-59	221.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_5657610_2	304371.MCP_2610	1.696e-39	152.0	COG0531@1|root,arCOG00009@2157|Archaea,2XTX6@28890|Euryarchaeota,2N9VR@224756|Methanomicrobia	224756|Methanomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS2_k127_5664837_0	1128398.Curi_c16780	7.424e-58	223.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,2683T@186813|unclassified Clostridiales	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5664837_1	1463854.JOHT01000007_gene3330	2.378e-24	112.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_5667654_0	1444309.JAQG01000065_gene2431	2.248e-55	200.0	COG3173@1|root,COG3173@2|Bacteria,1UIXX@1239|Firmicutes,4ISW9@91061|Bacilli,26VY7@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH
LZS2_k127_5672657_1	118168.MC7420_6923	4.518e-26	122.0	COG0681@1|root,COG0681@2|Bacteria,1G519@1117|Cyanobacteria,1HAKR@1150|Oscillatoriales	1117|Cyanobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
LZS2_k127_5672657_0	448385.sce2316	5.046e-32	128.0	COG1051@1|root,COG1051@2|Bacteria,1RF2T@1224|Proteobacteria,42Y18@68525|delta/epsilon subdivisions,2WSRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_5672691_0	204669.Acid345_4530	2.967e-73	273.0	COG4805@1|root,COG4805@2|Bacteria,3Y4PP@57723|Acidobacteria,2JKV8@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5672691_1	903818.KI912268_gene1906	1.719e-35	145.0	2D4UK@1|root,32THN@2|Bacteria,3Y59Q@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3142
LZS2_k127_5674525_2	386456.JQKN01000001_gene1800	2.063e-22	112.0	COG0642@1|root,COG0784@1|root,arCOG06712@1|root,arCOG02358@2157|Archaea,arCOG02386@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF,GAF_2,HATPase_c,HTH_10,HisKA,HisKA_4TM,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS2_k127_5674525_1	313624.NSP_48380	4.191e-51	185.0	COG0745@1|root,COG0745@2|Bacteria,1G51F@1117|Cyanobacteria,1HN3A@1161|Nostocales	1117|Cyanobacteria	T	PFAM response regulator receiver	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
LZS2_k127_5674525_0	386456.JQKN01000001_gene1802	3.914e-81	277.0	COG0642@1|root,COG3413@1|root,arCOG02348@1|root,arCOG02350@1|root,arCOG03567@1|root,arCOG06712@1|root,arCOG02278@2157|Archaea,arCOG02348@2157|Archaea,arCOG02350@2157|Archaea,arCOG02358@2157|Archaea,arCOG03567@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,HisKA_4TM,MEDS,PAS,PAS_3,PAS_4,PAS_9
LZS2_k127_5684054_1	255470.cbdbA560	4.722e-27	123.0	COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,34D7H@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS2_k127_5684054_3	945713.IALB_0952	1.491e-22	103.0	COG4704@1|root,COG4704@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
LZS2_k127_5684054_0	1278073.MYSTI_00905	1.312e-106	362.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,43BX1@68525|delta/epsilon subdivisions,2X77U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
LZS2_k127_5684054_2	1246484.D479_18539	8.212e-25	109.0	COG1215@1|root,COG1215@2|Bacteria,1UE3Q@1239|Firmicutes,4HCUV@91061|Bacilli,3NECV@45667|Halobacillus	91061|Bacilli	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_5684290_2	344747.PM8797T_18169	0.0002231	46.0	COG1044@1|root,COG1044@2|Bacteria,2IY8X@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
LZS2_k127_5684290_1	1173020.Cha6605_3566	1.1e-32	138.0	COG0774@1|root,COG0774@2|Bacteria,1G01M@1117|Cyanobacteria	1117|Cyanobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
LZS2_k127_5684290_0	489825.LYNGBM3L_28020	7.774e-60	215.0	COG5316@1|root,COG5316@2|Bacteria,1GD0X@1117|Cyanobacteria,1HESQ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5691772_2	103690.17131880	2.053e-06	59.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1G1QI@1117|Cyanobacteria	1117|Cyanobacteria	F	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_10,TPR_12,TPR_7
LZS2_k127_5691772_1	1128427.KB904821_gene847	3.841e-32	134.0	COG0484@1|root,COG0484@2|Bacteria,1G2FB@1117|Cyanobacteria,1H7JY@1150|Oscillatoriales	1117|Cyanobacteria	O	DnaJ-class molecular chaperone with C-terminal Zn finger domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
LZS2_k127_5691772_0	483218.BACPEC_00737	4.564e-44	165.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,268VT@186813|unclassified Clostridiales	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
LZS2_k127_5694593_2	177437.HRM2_22410	8.418e-10	67.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MIBK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS2_k127_5694593_0	1403313.AXBR01000002_gene4343	6.391e-187	597.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,1ZAY9@1386|Bacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS2_k127_5694593_1	574087.Acear_0042	2.653e-59	213.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,3WAQ9@53433|Halanaerobiales	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS2_k127_5703460_0	856793.MICA_1231	2.969e-190	599.0	COG0019@1|root,COG0019@2|Bacteria,1Q548@1224|Proteobacteria,2U39J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
LZS2_k127_5703460_1	856793.MICA_1230	1.655e-141	451.0	COG0031@1|root,COG0607@1|root,COG0031@2|Bacteria,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.1,2.8.1.2	ko:K00406,ko:K01011	ko00190,ko00270,ko00920,ko01100,ko01120,ko02020,ko04122,map00190,map00270,map00920,map01100,map01120,map02020,map04122	M00156	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3,PALP,Rhodanese
LZS2_k127_5707961_0	344747.PM8797T_15526	1.087e-141	458.0	COG3329@1|root,COG3329@2|Bacteria,2IXB4@203682|Planctomycetes	203682|Planctomycetes	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
LZS2_k127_5707961_4	1120925.F941_01268	3.093e-13	75.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,1SFMR@1236|Gammaproteobacteria,3NNC8@468|Moraxellaceae	1236|Gammaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_5707961_1	1122135.KB893144_gene1410	6.456e-50	183.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	ahpD	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS2_k127_5707961_2	1333998.M2A_0407	4.249e-46	176.0	COG1309@1|root,COG1309@2|Bacteria,1R67Z@1224|Proteobacteria,2TUIS@28211|Alphaproteobacteria,4BSNG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS2_k127_5707961_6	136037.KDR23320	6.309e-08	59.0	KOG3544@1|root,KOG3544@2759|Eukaryota,38CJN@33154|Opisthokonta,3BAFZ@33208|Metazoa,3CU1R@33213|Bilateria,41Y4D@6656|Arthropoda,3SHRE@50557|Insecta	33208|Metazoa	W	collagen	COL11A1	GO:0001501,GO:0001502,GO:0001503,GO:0001568,GO:0001654,GO:0001704,GO:0001706,GO:0001894,GO:0001944,GO:0002009,GO:0002011,GO:0002062,GO:0002063,GO:0003007,GO:0003008,GO:0003205,GO:0003206,GO:0003208,GO:0003229,GO:0003231,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005581,GO:0005583,GO:0005588,GO:0005592,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0006029,GO:0006807,GO:0006928,GO:0006950,GO:0007009,GO:0007155,GO:0007275,GO:0007369,GO:0007423,GO:0007492,GO:0007507,GO:0007517,GO:0007600,GO:0007601,GO:0007605,GO:0008150,GO:0008152,GO:0008201,GO:0009058,GO:0009059,GO:0009100,GO:0009581,GO:0009582,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009987,GO:0010256,GO:0010470,GO:0012505,GO:0014706,GO:0016043,GO:0016477,GO:0019538,GO:0019838,GO:0022603,GO:0022610,GO:0030020,GO:0030154,GO:0030198,GO:0030199,GO:0030674,GO:0031012,GO:0031974,GO:0032501,GO:0032502,GO:0032963,GO:0032964,GO:0032991,GO:0035313,GO:0035987,GO:0035989,GO:0040011,GO:0042060,GO:0042471,GO:0042472,GO:0042592,GO:0043009,GO:0043062,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043394,GO:0043583,GO:0043588,GO:0043933,GO:0044237,GO:0044238,GO:0044260,GO:0044319,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045112,GO:0045595,GO:0045596,GO:0045992,GO:0045995,GO:0048407,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048562,GO:0048568,GO:0048592,GO:0048598,GO:0048644,GO:0048646,GO:0048704,GO:0048705,GO:0048706,GO:0048729,GO:0048731,GO:0048738,GO:0048839,GO:0048856,GO:0048869,GO:0048870,GO:0048871,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050877,GO:0050896,GO:0050906,GO:0050910,GO:0050953,GO:0050954,GO:0050974,GO:0050982,GO:0051093,GO:0051128,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051606,GO:0051674,GO:0055008,GO:0055010,GO:0060021,GO:0060023,GO:0060090,GO:0060249,GO:0060415,GO:0060429,GO:0060537,GO:0061024,GO:0061061,GO:0061448,GO:0062009,GO:0062023,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0072358,GO:0072359,GO:0090504,GO:0090505,GO:0090596,GO:0097367,GO:0097435,GO:0098643,GO:0098644,GO:0098743,GO:0099080,GO:0099081,GO:0099512,GO:1901135,GO:1901564,GO:1901576,GO:1901681,GO:1903224,GO:1903225,GO:1904399,GO:2000026,GO:2000542	-	ko:K19721	ko04974,map04974	-	-	-	ko00000,ko00001,ko00536	-	-	-	COLFI,Collagen,Laminin_G_2
LZS2_k127_5707961_3	402777.KB235903_gene2184	4.129e-16	89.0	COG1073@1|root,COG1073@2|Bacteria,1G1YP@1117|Cyanobacteria,1H80J@1150|Oscillatoriales	1117|Cyanobacteria	S	Alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,PhoPQ_related
LZS2_k127_5707961_5	1235457.C404_03195	1.364e-12	78.0	COG1413@1|root,COG1413@2|Bacteria,1NB0I@1224|Proteobacteria,2W6DU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5711346_1	290397.Adeh_4241	1.307e-16	84.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_5711346_2	1296415.JACC01000006_gene1518	1.337e-12	74.0	COG0589@1|root,COG0589@2|Bacteria,4NJ0H@976|Bacteroidetes,1I0HV@117743|Flavobacteriia,2YKRI@290174|Aquimarina	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_5711346_0	1094558.ME5_00446	5.806e-33	130.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,48U4U@772|Bartonellaceae	28211|Alphaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_5711499_0	743722.Sph21_3706	4.271e-76	270.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,1IX19@117747|Sphingobacteriia	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
LZS2_k127_5711499_2	5911.EAR95020	5.69e-24	114.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_5711499_1	358681.BBR47_20360	1.102e-65	231.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,26QH3@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835,iYO844.BSU39420	DeoC
LZS2_k127_5713532_0	667014.Thein_1217	1.784e-107	357.0	COG1087@1|root,COG1087@2|Bacteria,2GIQU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS2_k127_571555_0	338963.Pcar_1474	1.342e-50	191.0	COG0457@1|root,COG0457@2|Bacteria,1QY6N@1224|Proteobacteria,42XBU@68525|delta/epsilon subdivisions,2WT6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_571555_1	643473.KB235930_gene1830	1.423e-32	134.0	2ASQB@1|root,31I58@2|Bacteria,1G6Z5@1117|Cyanobacteria,1HS1S@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
LZS2_k127_5717208_0	208444.JNYY01000008_gene8641	1.37e-74	261.0	COG0457@1|root,COG0457@2|Bacteria,2I7P1@201174|Actinobacteria,4DZWC@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,TPR_12
LZS2_k127_5717208_2	1173024.KI912149_gene5929	1.032e-60	222.0	COG0451@1|root,COG0451@2|Bacteria,1G2HE@1117|Cyanobacteria,1JJ90@1189|Stigonemataceae	1117|Cyanobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS2_k127_5717208_4	118166.JH976537_gene3102	2.03e-44	172.0	COG1191@1|root,COG1191@2|Bacteria,1G2IA@1117|Cyanobacteria,1H7MC@1150|Oscillatoriales	1117|Cyanobacteria	K	RNA polymerase sigma factor, sigma-70 family	sigF	-	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4,Sigma70_r4_2
LZS2_k127_5717208_1	321332.CYB_2400	2.677e-71	249.0	COG1131@1|root,COG1131@2|Bacteria,1G0UC@1117|Cyanobacteria,1GZN4@1129|Synechococcus	1117|Cyanobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_5717208_3	1265505.ATUG01000003_gene184	1.525e-44	171.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2MPXF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
LZS2_k127_5717208_6	370438.PTH_1144	2.304e-30	135.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,26256@186807|Peptococcaceae	186801|Clostridia	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
LZS2_k127_5717208_5	251221.35213002	6.666e-37	156.0	COG4972@1|root,COG4972@2|Bacteria,1G0A3@1117|Cyanobacteria	1117|Cyanobacteria	NU	Type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
LZS2_k127_5723118_0	1267533.KB906733_gene2963	2.759e-51	200.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,3Y2HT@57723|Acidobacteria,2JIGE@204432|Acidobacteriia	204432|Acidobacteriia	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS2_k127_5723710_1	1526927.Plano_0831	7.445e-22	97.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,26CVX@186818|Planococcaceae	91061|Bacilli	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	yhcZ	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_5723710_0	251221.35211376	6.701e-54	209.0	COG5002@1|root,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS2_k127_5723710_2	521045.Kole_0885	5.099e-07	54.0	COG0071@1|root,COG0071@2|Bacteria,2GDCG@200918|Thermotogae	200918|Thermotogae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS2_k127_572679_2	649639.Bcell_2408	8.456e-23	101.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,4HAF5@91061|Bacilli,1ZAXI@1386|Bacillus	91061|Bacilli	P	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance	ynbB	GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
LZS2_k127_572679_3	755178.Cyan10605_0108	2.129e-17	94.0	COG1040@1|root,COG1040@2|Bacteria,1G5P8@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM comF family protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
LZS2_k127_572679_0	1121423.JONT01000002_gene2190	2.815e-158	510.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,26072@186807|Peptococcaceae	186801|Clostridia	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_572679_1	649747.HMPREF0083_05360	4.076e-47	174.0	COG0526@1|root,COG0526@2|Bacteria,1V1R4@1239|Firmicutes,4HFWU@91061|Bacilli,272QM@186822|Paenibacillaceae	91061|Bacilli	CO	AhpC/TSA family	ykuV	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_5726878_1	386456.JQKN01000013_gene3073	9.95e-06	58.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota	28890|Euryarchaeota	O	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
LZS2_k127_5726878_0	1123313.ATUT01000022_gene1270	1.634e-39	151.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,3VQIB@526524|Erysipelotrichia	526524|Erysipelotrichia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_10,MafB19-deam
LZS2_k127_5749656_1	32057.KB217478_gene7079	0.0008665	48.0	COG1413@1|root,COG1413@2|Bacteria,1G6AT@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM Leucine rich repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_5749656_0	1537917.JU82_07670	4.429e-33	141.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42PTS@68525|delta/epsilon subdivisions,2YNBM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
LZS2_k127_575464_2	1499967.BAYZ01000105_gene3505	1.022e-25	120.0	COG0457@1|root,COG0457@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_575464_1	1123288.SOV_4c06600	1.367e-51	205.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_575464_0	886293.Sinac_1006	5.37e-69	245.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	rbn	-	-	ko:K03466,ko:K07058	-	-	-	-	ko00000,ko03036	3.A.12	-	-	Virul_fac_BrkB
LZS2_k127_576800_1	309799.DICTH_0563	2.139e-11	72.0	COG0392@1|root,COG5305@1|root,COG0392@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM,PMT_2
LZS2_k127_576800_0	582515.KR51_00001250	2.402e-71	258.0	COG0472@1|root,COG0472@2|Bacteria,1G1B9@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 4	lim	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
LZS2_k127_5769828_1	205922.Pfl01_2556	0.0008092	49.0	COG0454@1|root,COG0456@2|Bacteria,1RC8I@1224|Proteobacteria,1S3QP@1236|Gammaproteobacteria,1YQ7C@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	K	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS2_k127_5769828_0	1123371.ATXH01000002_gene352	1.281e-121	403.0	COG1473@1|root,COG1473@2|Bacteria,2GI9V@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_5780288_0	439481.Aboo_1400	7.955e-54	204.0	COG1506@1|root,arCOG01646@2157|Archaea	2157|Archaea	E	Peptidase S9 prolyl oligopeptidase active site	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Abhydrolase_1
LZS2_k127_5780288_1	1122919.KB905601_gene4396	1.606e-13	81.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,4HB78@91061|Bacilli,26QN2@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)	iolC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009987,GO:0016042,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044424,GO:0044464,GO:0046434,GO:0046835,GO:0071704,GO:1901575	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iYO844.BSU39740	PfkB
LZS2_k127_579474_0	269482.Bcep1808_2891	3.22e-101	340.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,1K0GY@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
LZS2_k127_579474_1	525903.Taci_1223	1.36e-25	117.0	COG0568@1|root,COG0568@2|Bacteria,3TACS@508458|Synergistetes	508458|Synergistetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_5798317_1	1499967.BAYZ01000097_gene4343	1.66e-39	160.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,2NP45@2323|unclassified Bacteria	2|Bacteria	M	Patatin-like phospholipase	plpD	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
LZS2_k127_5798317_3	470704.XP_007752929.1	0.0006739	50.0	28U30@1|root,2R0TM@2759|Eukaryota,3ASB1@33154|Opisthokonta,3PHNF@4751|Fungi,3R2FU@4890|Ascomycota,20NF5@147545|Eurotiomycetes,3MXDR@451870|Chaetothyriomycetidae	4751|Fungi	S	Clr5 domain	-	-	-	-	-	-	-	-	-	-	-	-	Clr5
LZS2_k127_5798317_2	909663.KI867150_gene2380	3.306e-36	159.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
LZS2_k127_5798317_0	1472716.KBK24_0101205	1.623e-116	382.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2VNDX@28216|Betaproteobacteria,1K0TY@119060|Burkholderiaceae	28216|Betaproteobacteria	V	beta-lactamase	ampC	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
LZS2_k127_5801535_0	102232.GLO73106DRAFT_00005260	1.475e-88	298.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria	1117|Cyanobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_5801535_1	521674.Plim_3737	1.079e-77	268.0	COG0265@1|root,COG0265@2|Bacteria,2IXU0@203682|Planctomycetes	203682|Planctomycetes	O	typically periplasmic contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_5820583_1	221288.JH992901_gene3319	1.128e-18	100.0	COG0457@1|root,COG0457@2|Bacteria,1G1QI@1117|Cyanobacteria,1JKFN@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_5820583_2	1206741.BAFX01000197_gene3577	1.702e-15	92.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria,4FWPS@85025|Nocardiaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_5820583_0	880072.Desac_2945	1.473e-25	125.0	COG0515@1|root,COG3266@1|root,COG0515@2|Bacteria,COG3266@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MRS2@213462|Syntrophobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase,TPR_8,cNMP_binding
LZS2_k127_582383_2	395961.Cyan7425_4383	3.466e-18	89.0	COG0735@1|root,COG0735@2|Bacteria,1G6R1@1117|Cyanobacteria,3KI8Y@43988|Cyanothece	1117|Cyanobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS2_k127_582383_1	497964.CfE428DRAFT_1651	3.527e-24	116.0	COG0515@1|root,COG0515@2|Bacteria,46TX9@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RicinB_lectin_2
LZS2_k127_582383_0	1037409.BJ6T_08890	1.4e-81	288.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,HEAT_2,HEAT_PBS,Metallophos,NACHT
LZS2_k127_582383_3	1037409.BJ6T_08910	2.29e-15	83.0	COG1100@1|root,COG1100@2|Bacteria,1R9PM@1224|Proteobacteria	1224|Proteobacteria	S	Small GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5825493_0	203124.Tery_0321	1.511e-38	157.0	COG4632@1|root,COG4632@2|Bacteria,1G30P@1117|Cyanobacteria,1HDHM@1150|Oscillatoriales	1117|Cyanobacteria	G	Exopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
LZS2_k127_5825493_1	1148.1653006	7.353e-08	62.0	2CFCI@1|root,32S1P@2|Bacteria,1G4ST@1117|Cyanobacteria,1H6IW@1142|Synechocystis	1117|Cyanobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
LZS2_k127_5825493_2	1173264.KI913949_gene3817	1.946e-06	57.0	2E35V@1|root,32Y5S@2|Bacteria,1G9GH@1117|Cyanobacteria,1HFTQ@1150|Oscillatoriales	1117|Cyanobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5826748_0	1173264.KI913949_gene1491	1.03e-198	623.0	COG0421@1|root,COG1586@1|root,COG0421@2|Bacteria,COG1586@2|Bacteria,1G36Y@1117|Cyanobacteria,1HH8X@1150|Oscillatoriales	1117|Cyanobacteria	E	Spermidine synthase tetramerisation domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
LZS2_k127_5828571_0	883109.HMPREF0380_00386	1.03e-164	537.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WCD0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
LZS2_k127_5828571_3	661478.OP10G_3914	1.244e-38	154.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS2_k127_5828571_1	1120972.AUMH01000019_gene2359	1.863e-151	491.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli,277WV@186823|Alicyclobacillaceae	91061|Bacilli	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
LZS2_k127_5828571_2	237368.SCABRO_03415	3.13e-110	360.0	COG0365@1|root,COG0365@2|Bacteria,2IX5P@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS2_k127_5835240_1	1379698.RBG1_1C00001G0787	1.591e-70	255.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2NQNA@2323|unclassified Bacteria	2|Bacteria	I	Fatty acid oxidation complex	fadJ	GO:0003674,GO:0003824,GO:0003857,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c26730,iETEC_1333.ETEC_2476,iEcE24377_1341.EcE24377A_2637,ic_1306.c2886	3HCDH,3HCDH_N,ECH_1
LZS2_k127_5835240_3	1459636.NTE_00536	7.389e-13	80.0	COG0346@1|root,arCOG02708@2157|Archaea	2157|Archaea	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
LZS2_k127_5835240_0	754476.Q7A_2591	4.689e-105	350.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria,460ZW@72273|Thiotrichales	72273|Thiotrichales	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_5835240_2	1304284.L21TH_0136	1.496e-42	161.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,36G1Q@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS2_k127_5837673_2	10228.TriadP62542	0.0001873	51.0	COG0457@1|root,COG3914@1|root,KOG1840@2759|Eukaryota,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Death,PH,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
LZS2_k127_5837673_0	324925.Ppha_0446	6.291e-14	84.0	COG0457@1|root,COG0457@2|Bacteria,1FD7Y@1090|Chlorobi	1090|Chlorobi	K	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7,TPR_8
LZS2_k127_5837673_1	391625.PPSIR1_21794	1.749e-05	48.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2WNTB@28221|Deltaproteobacteria,2Z0SP@29|Myxococcales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	truC	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
LZS2_k127_5840199_0	247634.GPB2148_1961	6.397e-71	252.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria,1J9AQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	proteins of the AP superfamily	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_5840199_1	1449126.JQKL01000035_gene2174	2.645e-35	139.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,2683T@186813|unclassified Clostridiales	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5845618_2	859657.RPSI07_mp0505	2.416e-74	257.0	COG2243@1|root,COG2243@2|Bacteria,1MV3G@1224|Proteobacteria,2VK3F@28216|Betaproteobacteria,1KFJM@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Precorrin-2 C20-methyltransferase	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
LZS2_k127_5845618_1	697282.Mettu_2778	3.49e-91	313.0	COG1903@1|root,COG1903@2|Bacteria,1MXU3@1224|Proteobacteria,1S016@1236|Gammaproteobacteria,1XGI0@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
LZS2_k127_5845618_0	748280.NH8B_1837	7.534e-134	435.0	COG2082@1|root,COG2138@1|root,COG2082@2|Bacteria,COG2138@2|Bacteria,1MX1E@1224|Proteobacteria,2VNZM@28216|Betaproteobacteria,2KPH7@206351|Neisseriales	206351|Neisseriales	H	Precorrin-8X methylmutase	cbiC	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC,CbiX
LZS2_k127_5845917_1	391623.TERMP_01057	1.822e-43	162.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,24458@183968|Thermococci	183968|Thermococci	E	Glyoxalase-like domain	-	GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
LZS2_k127_5845917_2	1469607.KK073768_gene3595	2.964e-17	95.0	COG0457@1|root,COG0457@2|Bacteria,1G1G9@1117|Cyanobacteria,1HKDX@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_5845917_0	572544.Ilyop_1413	4.783e-50	182.0	COG0615@1|root,COG0615@2|Bacteria,37A0X@32066|Fusobacteria	32066|Fusobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE2	-	2.7.7.39	ko:K00980	ko00564,map00564	-	R00856	RC00002	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like
LZS2_k127_5852532_1	240292.Ava_0432	7.467e-64	229.0	COG0793@1|root,COG0793@2|Bacteria,1G1YJ@1117|Cyanobacteria,1HKZG@1161|Nostocales	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
LZS2_k127_5852532_3	2325.TKV_c07360	1.771e-08	64.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia,42GSR@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
LZS2_k127_5852532_4	865861.AZSU01000003_gene1655	1.781e-05	51.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,36MIP@31979|Clostridiaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS2_k127_5852532_0	401526.TcarDRAFT_1771	6.544e-77	267.0	COG1806@1|root,COG1806@2|Bacteria,1TPG0@1239|Firmicutes,4H1V7@909932|Negativicutes	909932|Negativicutes	H	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
LZS2_k127_5852532_2	648996.Theam_1627	4.942e-60	215.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G4IJ@200783|Aquificae	200783|Aquificae	G	PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS2_k127_5857859_4	1408422.JHYF01000002_gene2549	5.079e-24	109.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,36EG4@31979|Clostridiaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
LZS2_k127_5857859_1	1430440.MGMSRv2_3724	2.765e-67	250.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2JSNQ@204441|Rhodospirillales	204441|Rhodospirillales	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
LZS2_k127_5857859_2	215803.DB30_7269	9.138e-32	127.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,434K9@68525|delta/epsilon subdivisions,2WYXI@28221|Deltaproteobacteria,2Z0V9@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_5857859_3	272134.KB731324_gene5522	1.239e-30	124.0	COG0745@1|root,COG0745@2|Bacteria,1G6Y0@1117|Cyanobacteria,1HBK8@1150|Oscillatoriales	1117|Cyanobacteria	KT	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_5857859_0	1390370.O203_22275	2.311e-90	317.0	COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RPI4@1236|Gammaproteobacteria,1YHI5@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,dCache_3
LZS2_k127_5864116_1	759914.BP951000_1900	0.0002544	44.0	COG0263@1|root,COG0263@2|Bacteria,2J6GB@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
LZS2_k127_5864116_0	197221.22294485	2.628e-138	452.0	COG0014@1|root,COG0014@2|Bacteria,1G1NS@1117|Cyanobacteria	1117|Cyanobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_5865017_0	240292.Ava_4732	1.276e-33	148.0	COG1511@1|root,COG1511@2|Bacteria,1G29D@1117|Cyanobacteria,1HQZW@1161|Nostocales	1117|Cyanobacteria	S	Tubulin like	-	-	-	-	-	-	-	-	-	-	-	-	Tubulin_2
LZS2_k127_5866049_1	1282360.ABAC460_17085	4.037e-44	169.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_5866049_0	1232410.KI421415_gene2947	5.005e-259	810.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,42P6X@68525|delta/epsilon subdivisions,2WK8U@28221|Deltaproteobacteria,43U3A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.7.5.1	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Molybdopterin,Molydop_binding
LZS2_k127_587204_3	1196323.ALKF01000171_gene690	0.0006279	48.0	COG3878@1|root,COG3878@2|Bacteria,1V0V3@1239|Firmicutes,4HMIQ@91061|Bacilli,26X0A@186822|Paenibacillaceae	91061|Bacilli	E	Domain of unknown function (DUF1963)	ywqG	-	-	-	-	-	-	-	-	-	-	-	DUF1963
LZS2_k127_587204_2	931276.Cspa_c39600	1.003e-05	50.0	COG3878@1|root,COG3878@2|Bacteria,1V0V3@1239|Firmicutes,24I4H@186801|Clostridia,36NYQ@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF1963)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
LZS2_k127_587204_0	316056.RPC_1039	4.571e-189	603.0	COG3177@1|root,COG3177@2|Bacteria,1MVW0@1224|Proteobacteria,2TU9A@28211|Alphaproteobacteria,3JV8G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
LZS2_k127_587204_1	35754.JNYJ01000001_gene7129	1.563e-20	100.0	COG2755@1|root,COG2755@2|Bacteria,2IP29@201174|Actinobacteria,4DEWE@85008|Micromonosporales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS2_k127_5872871_1	1379698.RBG1_1C00001G0716	3.842e-10	66.0	COG2050@1|root,COG2050@2|Bacteria,2NRYC@2323|unclassified Bacteria	2|Bacteria	Q	Domain of unknown function (DUF4442)	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
LZS2_k127_5872871_0	1183438.GKIL_2029	5.941e-39	166.0	COG1538@1|root,COG1538@2|Bacteria	1183438.GKIL_2029|-	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	-
LZS2_k127_5874365_0	1158612.I580_02541	7.606e-94	320.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,4B10E@81852|Enterococcaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
LZS2_k127_5874365_1	879308.HMPREF9130_1719	2.01e-20	97.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,22HPG@1570339|Peptoniphilaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS2_k127_5874365_2	1499967.BAYZ01000119_gene3228	1.716e-19	96.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS2_k127_5874365_3	667014.Thein_0207	9.981e-05	49.0	COG0130@1|root,COG0130@2|Bacteria,2GHKQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
LZS2_k127_5876831_0	1501230.ET33_04380	1.601e-101	342.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli,26S8W@186822|Paenibacillaceae	91061|Bacilli	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS2_k127_5876831_1	393595.ABO_0963	6.191e-06	59.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,1XJGR@135619|Oceanospirillales	135619|Oceanospirillales	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
LZS2_k127_5890029_4	596151.DesfrDRAFT_0282	1.121e-05	57.0	2AD1R@1|root,312PX@2|Bacteria,1QCNM@1224|Proteobacteria,433DK@68525|delta/epsilon subdivisions,2WY1V@28221|Deltaproteobacteria,2M8UB@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
LZS2_k127_5890029_1	43989.cce_1737	7.228e-52	198.0	COG5002@1|root,COG5002@2|Bacteria,1GPX6@1117|Cyanobacteria,3KGZ0@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_5890029_0	321332.CYB_2462	6.265e-68	239.0	COG0483@1|root,COG0483@2|Bacteria,1G09G@1117|Cyanobacteria,1H2E5@1129|Synechococcus	1117|Cyanobacteria	G	Inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
LZS2_k127_5890029_2	1267535.KB906767_gene657	7.959e-47	179.0	COG0483@1|root,COG0483@2|Bacteria,3Y3GD@57723|Acidobacteria,2JHRB@204432|Acidobacteriia	2|Bacteria	G	Inositol monophosphatase	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659	3.1.3.15,3.1.3.25,3.1.3.93	ko:K01092,ko:K05602,ko:K18649	ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00114,M00131	R01185,R01186,R01187,R03013,R07674	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
LZS2_k127_5890029_3	118173.KB235914_gene856	3.115e-15	83.0	COG3659@1|root,COG3659@2|Bacteria,1G0XI@1117|Cyanobacteria,1H76F@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Carbohydrate-selective porin, OprB family	-	-	-	-	-	-	-	-	-	-	-	-	OprB,SLH
LZS2_k127_589379_0	1408445.JHXP01000014_gene1418	1.713e-121	404.0	COG0277@1|root,COG0277@2|Bacteria,1MV1Q@1224|Proteobacteria,1RSC3@1236|Gammaproteobacteria,1JDAH@118969|Legionellales	118969|Legionellales	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
LZS2_k127_5897858_0	1183438.GKIL_0853	4.103e-142	485.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1G45B@1117|Cyanobacteria	1117|Cyanobacteria	PT	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
LZS2_k127_5897858_1	443143.GM18_0109	1.041e-05	57.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
LZS2_k127_5897858_2	234267.Acid_7272	0.0004132	44.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,3Y2IR@57723|Acidobacteria	57723|Acidobacteria	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
LZS2_k127_5903455_2	521674.Plim_2357	2.911e-05	49.0	COG0457@1|root,COG0457@2|Bacteria,2J3CZ@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
LZS2_k127_5903455_0	1232437.KL662076_gene3460	9.732e-21	108.0	COG4249@1|root,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions,2WSC3@28221|Deltaproteobacteria,2MN4H@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TIR_2,WD40
LZS2_k127_5903455_1	126957.SMAR006354-PA	4.714e-19	103.0	COG0457@1|root,KOG1840@2759|Eukaryota,38CFM@33154|Opisthokonta,3BC82@33208|Metazoa,3CWNT@33213|Bilateria,41VXH@6656|Arthropoda	33208|Metazoa	Z	Kinesin light	KLC4	GO:0000003,GO:0000226,GO:0000280,GO:0000902,GO:0000904,GO:0000910,GO:0002064,GO:0002065,GO:0002066,GO:0002119,GO:0002164,GO:0002376,GO:0002478,GO:0002495,GO:0002504,GO:0003006,GO:0003674,GO:0003774,GO:0003777,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005829,GO:0005856,GO:0005871,GO:0005875,GO:0005929,GO:0006810,GO:0006886,GO:0006890,GO:0006928,GO:0006996,GO:0007010,GO:0007017,GO:0007018,GO:0007049,GO:0007097,GO:0007143,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007304,GO:0007306,GO:0007399,GO:0007409,GO:0008088,GO:0008092,GO:0008104,GO:0008150,GO:0009653,GO:0009791,GO:0009888,GO:0009987,GO:0010927,GO:0010970,GO:0012505,GO:0015031,GO:0015630,GO:0015631,GO:0015833,GO:0016020,GO:0016043,GO:0016049,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016938,GO:0017111,GO:0019882,GO:0019884,GO:0019886,GO:0019894,GO:0019953,GO:0022008,GO:0022402,GO:0022411,GO:0022412,GO:0022414,GO:0022607,GO:0030030,GO:0030154,GO:0030182,GO:0030424,GO:0030426,GO:0030427,GO:0030473,GO:0030703,GO:0030705,GO:0030707,GO:0030855,GO:0031175,GO:0031410,GO:0031967,GO:0031975,GO:0031982,GO:0032501,GO:0032502,GO:0032504,GO:0032984,GO:0032988,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033206,GO:0033267,GO:0034613,GO:0035253,GO:0035418,GO:0035617,GO:0036477,GO:0040007,GO:0040011,GO:0040038,GO:0042886,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044703,GO:0045184,GO:0046843,GO:0046907,GO:0048002,GO:0048193,GO:0048285,GO:0048468,GO:0048477,GO:0048489,GO:0048588,GO:0048589,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048675,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0051179,GO:0051234,GO:0051293,GO:0051295,GO:0051301,GO:0051321,GO:0051640,GO:0051641,GO:0051647,GO:0051648,GO:0051649,GO:0051650,GO:0051653,GO:0051656,GO:0051704,GO:0060429,GO:0060560,GO:0061564,GO:0061640,GO:0070727,GO:0071702,GO:0071705,GO:0071826,GO:0071840,GO:0072384,GO:0097458,GO:0097479,GO:0097480,GO:0097708,GO:0099003,GO:0099111,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0140013,GO:0150034,GO:1903008,GO:1903046,GO:1990138	-	ko:K10407	ko05132,map05132	-	-	-	ko00000,ko00001,ko03019,ko04812	-	-	-	DUF2315,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_5906859_1	639030.JHVA01000001_gene165	8.955e-06	54.0	COG2823@1|root,COG2823@2|Bacteria,3Y4FV@57723|Acidobacteria,2JJ5I@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS2_k127_5906859_0	1134413.ANNK01000162_gene3531	2.745e-89	308.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4HBCX@91061|Bacilli,1ZDE3@1386|Bacillus	91061|Bacilli	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_5906859_2	43989.cce_0316	0.0001124	46.0	COG0631@1|root,COG0631@2|Bacteria,1G2FY@1117|Cyanobacteria,3KGT7@43988|Cyanothece	1117|Cyanobacteria	T	SMART protein phosphatase 2C domain protein	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
LZS2_k127_5911595_0	44454.NF84_00090	1.154e-55	207.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,233BZ@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5911595_1	1192034.CAP_7335	1.576e-08	67.0	COG1187@1|root,COG2885@1|root,COG1187@2|Bacteria,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,42SM6@68525|delta/epsilon subdivisions,2X3B1@28221|Deltaproteobacteria,2YV6X@29|Myxococcales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA
LZS2_k127_5911595_2	485918.Cpin_4404	4.975e-08	63.0	COG3831@1|root,COG3831@2|Bacteria	2|Bacteria	-	-	-	-	2.4.2.30	ko:K10798	ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400	-	-	-	DUF4240,PARP,WGR
LZS2_k127_5917724_1	1382306.JNIM01000001_gene107	1.797e-33	151.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,zinc_ribbon_2
LZS2_k127_5917724_2	1121091.AUMP01000036_gene3928	1.518e-15	85.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli	91061|Bacilli	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_5917724_0	265072.Mfla_0125	7.428e-46	169.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,2VSN3@28216|Betaproteobacteria,2KMS3@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
LZS2_k127_5922880_1	471870.BACINT_02833	7.19e-87	308.0	COG2755@1|root,COG2755@2|Bacteria,4NK31@976|Bacteroidetes,2G3HM@200643|Bacteroidia,4AWEB@815|Bacteroidaceae	976|Bacteroidetes	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
LZS2_k127_5922880_3	1117379.BABA_12835	2.114e-77	274.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,4HA0E@91061|Bacilli,1ZDF1@1386|Bacillus	91061|Bacilli	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
LZS2_k127_5922880_4	268407.PWYN_19850	1.641e-71	254.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,26QJX@186822|Paenibacillaceae	91061|Bacilli	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
LZS2_k127_5922880_0	997346.HMPREF9374_0898	2.17e-101	341.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,27BAZ@186824|Thermoactinomycetaceae	91061|Bacilli	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS2_k127_5922880_2	113355.CM001775_gene274	5.702e-80	278.0	COG0416@1|root,COG0416@2|Bacteria,1G1CT@1117|Cyanobacteria	1117|Cyanobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
LZS2_k127_5922880_6	1386089.N865_17875	2.13e-12	69.0	COG0333@1|root,COG0333@2|Bacteria,2GQP3@201174|Actinobacteria,4FHSH@85021|Intrasporangiaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
LZS2_k127_5922880_7	1121428.DESHY_40054___1	0.0009359	48.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,26257@186807|Peptococcaceae	186801|Clostridia	S	metal-binding protein, possibly nucleic-acid binding protein	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
LZS2_k127_5922880_5	574087.Acear_0510	3.166e-26	117.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3WB7T@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
LZS2_k127_5933884_0	765911.Thivi_3415	8.149e-119	394.0	COG2271@1|root,COG2271@2|Bacteria,1MUEK@1224|Proteobacteria,1RMB4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Major facilitator superfamily	-	-	-	ko:K13021	-	-	-	-	ko00000,ko02000	2.A.1.14.3	-	-	MFS_1
LZS2_k127_5933884_1	1408311.JNJM01000005_gene1615	8.736e-52	193.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,2PS46@265975|Oribacterium	186801|Clostridia	E	Amino acid kinase family	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
LZS2_k127_5933884_2	86416.Clopa_3123	1.993e-20	94.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,36E48@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
LZS2_k127_5935471_0	1267535.KB906767_gene934	4.66e-23	116.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
LZS2_k127_5935471_1	1267535.KB906767_gene999	1.244e-15	80.0	COG0531@1|root,COG0531@2|Bacteria,3Y2R3@57723|Acidobacteria,2JI6R@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS2_k127_5946932_0	1298867.AUES01000001_gene1649	4.814e-97	342.0	COG0421@1|root,COG0421@2|Bacteria,1PD54@1224|Proteobacteria,2V9CT@28211|Alphaproteobacteria,3JYAK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
LZS2_k127_5946932_1	1121405.dsmv_1320	3.549e-90	302.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS2_k127_5947812_0	269084.syc1418_d	1.84e-248	784.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1GZR8@1129|Synechococcus	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS2_k127_5949274_2	1144888.CM001467_gene1008	3.438e-23	101.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2TTG7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	InterPro IPR001584 COGs COG2801	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_3
LZS2_k127_5949274_0	1033743.CAES01000098_gene2690	1.362e-98	333.0	COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,26V2H@186822|Paenibacillaceae	91061|Bacilli	Q	cytochrome P450	bioI	GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.14.14.46	ko:K16593	ko00780,ko01100,map00780,map01100	M00573	R10123	-	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
LZS2_k127_5949274_1	1089549.AZUQ01000001_gene665	1.218e-49	189.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4EY9U@85014|Glycomycetales	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_5952765_0	497964.CfE428DRAFT_3430	1.793e-70	249.0	COG3975@1|root,COG3975@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	Peptidase_M61
LZS2_k127_5962852_0	765914.ThisiDRAFT_1291	2.172e-20	94.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,1WWGI@135613|Chromatiales	135613|Chromatiales	KO	TIGRFAM Hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
LZS2_k127_5962852_1	546271.Selsp_0119	9.924e-10	64.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,4H581@909932|Negativicutes	909932|Negativicutes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
LZS2_k127_5962852_2	237368.SCABRO_00339	7.568e-06	55.0	COG2993@1|root,COG2993@2|Bacteria	2|Bacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	fixO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,FixO
LZS2_k127_598185_1	1246474.ANBE01000011_gene3625	8.939e-07	57.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,HTH_31,HTH_Crp_2,NB-ARC,TPR_10,TPR_12,Trans_reg_C,cNMP_binding
LZS2_k127_598185_0	926550.CLDAP_00860	2.716e-12	66.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_5982297_1	1210884.HG799464_gene10957	1.515e-10	71.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
LZS2_k127_5982297_0	344747.PM8797T_27914	2.758e-150	483.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2IXGZ@203682|Planctomycetes	203682|Planctomycetes	M	cyanophycin synthetase	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS2_k127_5983236_1	1094980.Mpsy_2025	5.017e-05	54.0	arCOG06292@1|root,arCOG06292@2157|Archaea,2Y6XX@28890|Euryarchaeota,2NBBN@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5994691_0	28532.XP_010550828.1	1.602e-07	61.0	COG3914@1|root,KOG4626@2759|Eukaryota,37RD4@33090|Viridiplantae,3G7FD@35493|Streptophyta,3HNZP@3699|Brassicales	35493|Streptophyta	GOT	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC	-	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_5997292_0	1123371.ATXH01000002_gene341	3.161e-82	287.0	COG0123@1|root,COG0123@2|Bacteria,2GHD6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS2_k127_5997292_2	1121413.JMKT01000008_gene1641	3.478e-45	179.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2M971@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
LZS2_k127_5997292_1	883156.HMPREF9282_01496	1.453e-80	280.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4H2PQ@909932|Negativicutes	909932|Negativicutes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_599922_0	1146883.BLASA_1782	4.061e-73	264.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
LZS2_k127_599922_1	1123376.AUIU01000014_gene518	2.461e-07	63.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	atoC	-	-	ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_6001642_3	935557.ATYB01000014_gene2924	2.799e-06	57.0	COG3577@1|root,COG3577@2|Bacteria,1MZCI@1224|Proteobacteria,2U9K2@28211|Alphaproteobacteria,4BB24@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	protease	MA20_25915	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	Asp_protease_2,gag-asp_proteas
LZS2_k127_6001642_1	868595.Desca_1067	4.773e-61	214.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,261H1@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
LZS2_k127_6001642_0	861299.J421_3116	7.4e-166	531.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1ZT7J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
LZS2_k127_6001642_2	1348338.ADILRU_2484	1.3e-47	179.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,4FNHN@85023|Microbacteriaceae	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
LZS2_k127_6003498_1	502025.Hoch_6650	2.216e-86	289.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2WJNB@28221|Deltaproteobacteria,2YU00@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS2_k127_6003498_2	103690.17129790	3.844e-83	294.0	COG0845@1|root,COG0845@2|Bacteria,1G01U@1117|Cyanobacteria,1HM23@1161|Nostocales	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS2_k127_6003498_0	251221.35211336	6.895e-118	393.0	COG0577@1|root,COG0577@2|Bacteria,1G0A8@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_6003498_3	1041826.FCOL_12140	3.155e-80	273.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia,2NTAX@237|Flavobacterium	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_6007990_0	1242864.D187_008547	0.0001148	55.0	COG0745@1|root,COG0745@2|Bacteria,1NQ8U@1224|Proteobacteria	1224|Proteobacteria	KT	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
LZS2_k127_600981_1	1173027.Mic7113_4717	2.066e-39	150.0	COG1397@1|root,COG1397@2|Bacteria,1G437@1117|Cyanobacteria,1H9KV@1150|Oscillatoriales	1117|Cyanobacteria	O	ADP-ribosylglycohydrolase	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
LZS2_k127_600981_4	304371.MCP_2443	1.207e-15	88.0	arCOG08211@1|root,arCOG08211@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_600981_0	1047013.AQSP01000133_gene2112	1.995e-133	447.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
LZS2_k127_600981_2	638303.Thal_0887	1.442e-27	114.0	COG1324@1|root,COG1324@2|Bacteria,2G58I@200783|Aquificae	200783|Aquificae	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
LZS2_k127_600981_5	768710.DesyoDRAFT_3412	3.937e-11	74.0	28IU2@1|root,2Z8SW@2|Bacteria,1UYKP@1239|Firmicutes,24E5D@186801|Clostridia,2610H@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_600981_3	1123400.KB904749_gene718	1.553e-26	118.0	COG1463@1|root,COG1463@2|Bacteria,1RHH6@1224|Proteobacteria,1S74Q@1236|Gammaproteobacteria,4614U@72273|Thiotrichales	72273|Thiotrichales	Q	Protein of unknown function (DUF3465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3465
LZS2_k127_6026457_1	1347086.CCBA010000020_gene2766	6.735e-05	46.0	COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli,1ZGPI@1386|Bacillus	91061|Bacilli	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	uspA	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_6026457_0	1405.DJ92_240	2.324e-47	184.0	COG2132@1|root,COG2132@2|Bacteria,1TQJK@1239|Firmicutes,4IRUW@91061|Bacilli,1ZBEQ@1386|Bacillus	91061|Bacilli	Q	Multi-copper	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
LZS2_k127_6026457_2	118005.AWNK01000003_gene2437	0.000172	49.0	28WSE@1|root,2ZIS3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6031640_0	865861.AZSU01000001_gene378	2.965e-29	119.0	COG2154@1|root,COG2154@2|Bacteria,1VERE@1239|Firmicutes,24NE1@186801|Clostridia,36SAJ@31979|Clostridiaceae	186801|Clostridia	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
LZS2_k127_6031640_2	715226.ABI_07770	3.406e-10	71.0	COG2314@1|root,COG2314@2|Bacteria,1RJJN@1224|Proteobacteria,2UNH5@28211|Alphaproteobacteria,2KJQX@204458|Caulobacterales	204458|Caulobacterales	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
LZS2_k127_6031640_1	1230338.MOMA_01300	5.155e-11	66.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,3NIKG@468|Moraxellaceae	1236|Gammaproteobacteria	O	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_6031801_0	316067.Geob_3360	1.014e-99	350.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,43TCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
LZS2_k127_6035053_0	886293.Sinac_7521	3.223e-49	186.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Pur_ac_phosph_N,SLH
LZS2_k127_6035053_1	4558.Sb04g011030.1	0.0004444	50.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37SIR@33090|Viridiplantae,3GAVF@35493|Streptophyta,3KUMG@4447|Liliopsida,3ICZG@38820|Poales	35493|Streptophyta	E	Leucine Rich repeat	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.4.19.5	ko:K10268,ko:K13051	-	-	-	-	ko00000,ko01000,ko01002,ko04121	-	-	-	LRR_6
LZS2_k127_6036559_1	1278073.MYSTI_00937	2.29e-79	267.0	COG1917@1|root,COG1917@2|Bacteria,1QVVQ@1224|Proteobacteria	1224|Proteobacteria	S	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate	nbaC	GO:0000334,GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0044237,GO:0044248,GO:0051213,GO:0055114	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO
LZS2_k127_6036559_2	525373.HMPREF0766_12145	6.515e-15	82.0	COG0589@1|root,COG0589@2|Bacteria,4NWM6@976|Bacteroidetes,1IT81@117747|Sphingobacteriia	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_6036559_0	326423.RBAM_015480	1.452e-175	582.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli,1ZCDJ@1386|Bacillus	91061|Bacilli	P	COG0474 Cation transport ATPase	yloB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	iYO844.BSU15650	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
LZS2_k127_603911_4	1394178.AWOO02000009_gene4364	0.0007442	43.0	COG2124@1|root,COG2124@2|Bacteria,2IMGI@201174|Actinobacteria	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
LZS2_k127_603911_3	1232410.KI421421_gene3631	3.441e-29	133.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,42MNS@68525|delta/epsilon subdivisions,2WSQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
LZS2_k127_603911_1	1210884.HG799476_gene15346	5.875e-60	215.0	COG2935@1|root,COG2935@2|Bacteria,2IZT8@203682|Planctomycetes	203682|Planctomycetes	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
LZS2_k127_603911_2	706587.Desti_5123	1.439e-33	136.0	COG1525@1|root,COG2169@1|root,COG1525@2|Bacteria,COG2169@2|Bacteria,1N145@1224|Proteobacteria,42SG5@68525|delta/epsilon subdivisions,2WNPI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM nuclease (SNase domain protein)	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,Excalibur,SNase
LZS2_k127_603911_0	391625.PPSIR1_31263	1.704e-89	313.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKYM@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	GT	Phosphoenolpyruvate synthase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
LZS2_k127_6044102_1	290512.Paes_0460	4.314e-42	162.0	COG0546@1|root,COG0546@2|Bacteria,1FDVN@1090|Chlorobi	1090|Chlorobi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS2_k127_6044102_0	357808.RoseRS_1949	2.874e-44	186.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
LZS2_k127_6049500_0	1303518.CCALI_01070	1.493e-96	325.0	COG1816@1|root,COG1816@2|Bacteria	2|Bacteria	F	deaminase activity	add	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
LZS2_k127_6049500_2	251221.35211536	4.954e-32	134.0	COG0652@1|root,COG0652@2|Bacteria,1G1XY@1117|Cyanobacteria	1117|Cyanobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
LZS2_k127_6049500_1	1303518.CCALI_02613	2.141e-36	140.0	COG2360@1|root,COG2360@2|Bacteria	2|Bacteria	O	leucyltransferase activity	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
LZS2_k127_6055046_0	498761.HM1_1824	1.831e-76	263.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
LZS2_k127_6055046_1	41431.PCC8801_1837	1.155e-08	68.0	COG0457@1|root,COG0457@2|Bacteria,1G7GZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
LZS2_k127_6125762_2	1123508.JH636440_gene2532	6.21e-05	55.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2J07X@203682|Planctomycetes	203682|Planctomycetes	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_6125762_0	886293.Sinac_5809	1.479e-60	219.0	COG1028@1|root,COG1028@2|Bacteria,2J0Y9@203682|Planctomycetes	203682|Planctomycetes	IQ	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_6125762_1	1278073.MYSTI_01166	4.595e-20	100.0	COG0436@1|root,COG2890@1|root,COG0436@2|Bacteria,COG2890@2|Bacteria,1P71G@1224|Proteobacteria,4392Z@68525|delta/epsilon subdivisions,2X48U@28221|Deltaproteobacteria,2YYI8@29|Myxococcales	28221|Deltaproteobacteria	EJ	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS2_k127_6126982_0	99598.Cal7507_4247	4.139e-136	443.0	COG3854@1|root,COG3854@2|Bacteria,1G0U1@1117|Cyanobacteria,1HIKJ@1161|Nostocales	1117|Cyanobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	ycf45	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
LZS2_k127_6126982_1	224308.BSU00270	3.785e-62	232.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,4HBGC@91061|Bacilli,1ZBKS@1386|Bacillus	91061|Bacilli	E	Orn Lys Arg decarboxylase	yaaO	-	-	-	-	-	-	-	-	-	-	-	OKR_DC_1,OKR_DC_1_C
LZS2_k127_6126982_2	886293.Sinac_2313	2.244e-26	117.0	COG1011@1|root,COG1011@2|Bacteria,2J12R@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS2_k127_6128612_0	395961.Cyan7425_0119	2.449e-35	137.0	COG3328@1|root,COG3328@2|Bacteria,1G3YG@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
LZS2_k127_6132638_3	1342301.JASD01000008_gene1574	8.93e-05	47.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,3ZWU9@60136|Sulfitobacter	28211|Alphaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS2_k127_6132638_1	656519.Halsa_1234	1.195e-08	59.0	COG0702@1|root,COG0702@2|Bacteria,1V10W@1239|Firmicutes,24Q4V@186801|Clostridia	186801|Clostridia	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
LZS2_k127_6132638_0	595460.RRSWK_06141	1.109e-17	86.0	COG1937@1|root,COG1937@2|Bacteria,2J1A9@203682|Planctomycetes	203682|Planctomycetes	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
LZS2_k127_6132638_2	1313421.JHBV01000003_gene657	1.738e-05	55.0	COG4232@1|root,COG4232@2|Bacteria,4NIXX@976|Bacteroidetes,1ISA3@117747|Sphingobacteriia	976|Bacteroidetes	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_2,Thioredoxin_7
LZS2_k127_6135851_2	671143.DAMO_3035	7.763e-60	216.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	hemG	-	1.14.19.9,1.3.3.15,1.3.3.4	ko:K00231,ko:K14266	ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130	M00121,M00789,M00790	R03222,R04178,R09570	RC00885,RC00949	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
LZS2_k127_6135851_1	330214.NIDE1215	1.369e-104	350.0	COG0407@1|root,COG0407@2|Bacteria,3J0C3@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
LZS2_k127_6135851_3	1280692.AUJL01000001_gene32	7.916e-42	166.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,36E0J@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS2_k127_6135851_0	1183438.GKIL_1862	7.542e-164	524.0	COG0761@1|root,COG0761@2|Bacteria,1G10V@1117|Cyanobacteria	1117|Cyanobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
LZS2_k127_6135851_4	273068.TTE1983	5.748e-34	139.0	COG0637@1|root,COG0637@2|Bacteria,1V1NW@1239|Firmicutes,24G37@186801|Clostridia,42G6E@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,HAD_2
LZS2_k127_613615_1	747365.Thena_1446	1.827e-70	246.0	COG2271@1|root,COG2271@2|Bacteria,1TP6X@1239|Firmicutes,247PZ@186801|Clostridia,42IGT@68295|Thermoanaerobacterales	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	ko:K03535,ko:K08194	-	-	-	-	ko00000,ko02000	2.A.1.14.1,2.A.1.14.7	-	-	MFS_1
LZS2_k127_613615_0	686340.Metal_3888	2.604e-184	585.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RRAS@1236|Gammaproteobacteria,1XEII@135618|Methylococcales	135618|Methylococcales	S	flavoprotein, PP_4765 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
LZS2_k127_613615_2	56107.Cylst_2734	9.633e-38	151.0	COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,1G027@1117|Cyanobacteria,1HRQI@1161|Nostocales	1117|Cyanobacteria	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt,Response_reg,Trans_reg_C
LZS2_k127_6141029_2	1183438.GKIL_3179	2.269e-09	63.0	COG1538@1|root,COG1538@2|Bacteria,1G0B8@1117|Cyanobacteria	1117|Cyanobacteria	MU	outer membrane efflux protein	-	-	-	ko:K03287	-	-	-	-	ko00000	1.B.17	-	-	OEP
LZS2_k127_6141029_0	63737.Npun_F4015	0.0	1084.0	COG0841@1|root,COG0841@2|Bacteria,1G0C2@1117|Cyanobacteria,1HKD3@1161|Nostocales	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_6141029_1	395961.Cyan7425_4993	2.9e-52	192.0	COG0845@1|root,COG0845@2|Bacteria,1G0KI@1117|Cyanobacteria,3KHAE@43988|Cyanothece	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS2_k127_6145634_0	153721.MYP_2527	2.787e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,4NJEF@976|Bacteroidetes,47Q7U@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_16,TPR_2,TPR_8
LZS2_k127_6156497_1	216142.LT40_00395	1.209e-66	230.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Succinyldiaminopimelate	dapC	-	2.6.1.17	ko:K14261,ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_6156497_0	155515.JP36_08065	9.669e-134	430.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1Y6YY@135625|Pasteurellales	135625|Pasteurellales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
LZS2_k127_6156497_2	4792.ETI52086	2.66e-05	55.0	COG2202@1|root,KOG0500@1|root,KOG0500@2759|Eukaryota,KOG0501@2759|Eukaryota,3QEVK@4776|Peronosporales	4776|Peronosporales	P	Ion transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans,cNMP_binding
LZS2_k127_6163869_2	497965.Cyan7822_5141	9.242e-09	68.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1G1QI@1117|Cyanobacteria,3KHNA@43988|Cyanothece	1117|Cyanobacteria	K	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_6163869_0	194439.CT1603	2.67e-159	511.0	COG0205@1|root,COG0205@2|Bacteria,1FEH2@1090|Chlorobi	1090|Chlorobi	G	PFAM phosphofructokinase	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
LZS2_k127_6163869_1	862908.BMS_2693	3.66e-14	77.0	COG0287@1|root,COG0287@2|Bacteria,1QA4K@1224|Proteobacteria,42V3B@68525|delta/epsilon subdivisions,2WRIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
LZS2_k127_617472_1	304371.MCP_0432	1.166e-25	113.0	COG0433@1|root,arCOG09167@1|root,arCOG00280@2157|Archaea,arCOG00286@2157|Archaea,arCOG09167@2157|Archaea	2157|Archaea	P	protein kinase activity	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
LZS2_k127_617472_2	272560.BPSS1140	3.405e-25	117.0	COG0589@1|root,COG0589@2|Bacteria,1NZ7U@1224|Proteobacteria,2W3MC@28216|Betaproteobacteria,1K4K5@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_617472_0	272624.lpg2396	9.923e-124	406.0	COG2230@1|root,COG2230@2|Bacteria,1QY55@1224|Proteobacteria,1RYEN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS2_k127_617472_3	1121875.KB907550_gene795	1.343e-18	87.0	COG4638@1|root,COG4638@2|Bacteria,4NJ33@976|Bacteroidetes,1HZFM@117743|Flavobacteriia	976|Bacteroidetes	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
LZS2_k127_6178243_2	118168.MC7420_1014	2.679e-06	51.0	COG3541@1|root,COG3541@2|Bacteria,1G2ZU@1117|Cyanobacteria,1H99U@1150|Oscillatoriales	1117|Cyanobacteria	S	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
LZS2_k127_6178243_0	1005048.CFU_3313	3.712e-16	81.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,2VXAA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
LZS2_k127_6178243_1	927677.ALVU02000007_gene4718	1.014e-13	78.0	COG3514@1|root,COG3514@2|Bacteria,1G9X2@1117|Cyanobacteria	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
LZS2_k127_6182670_2	307480.IW16_23130	1.201e-25	117.0	COG1028@1|root,COG2070@1|root,COG3321@1|root,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,4NJWH@976|Bacteroidetes,1IIQ2@117743|Flavobacteriia,3ZNP4@59732|Chryseobacterium	976|Bacteroidetes	IQ	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,ketoacyl-synt
LZS2_k127_6182670_0	1117314.PCIT_13169	1.334e-88	313.0	COG3568@1|root,COG3568@2|Bacteria,1R3X8@1224|Proteobacteria,1RZYH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
LZS2_k127_6182670_1	344747.PM8797T_25901	8.012e-49	187.0	COG3781@1|root,COG3781@2|Bacteria,2IZZ2@203682|Planctomycetes	203682|Planctomycetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
LZS2_k127_6182698_0	706587.Desti_0542	2.123e-167	543.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2MQ7A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
LZS2_k127_6203853_0	313606.M23134_08444	2.283e-13	80.0	2FC23@1|root,34461@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6212113_1	402777.KB235903_gene2469	6.173e-35	145.0	COG0330@1|root,COG0330@2|Bacteria,1G37J@1117|Cyanobacteria,1H9TF@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_6212113_0	926550.CLDAP_30600	4.15e-60	216.0	COG1478@1|root,COG1478@2|Bacteria	2|Bacteria	S	coenzyme F420-1:gamma-L-glutamate ligase activity	CP_1112	-	6.3.2.12,6.3.2.17,6.3.2.31,6.3.2.34	ko:K12234,ko:K22099	ko00680,ko00790,ko01120,map00680,map00790,map01120	M00378,M00840	R00942,R02237,R04241,R09399,R09400	RC00064,RC00090,RC00141,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
LZS2_k127_6242638_1	439235.Dalk_2335	9.911e-132	434.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria,2MI2V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
LZS2_k127_6242638_0	396588.Tgr7_1394	9.539e-152	492.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,1RNGJ@1236|Gammaproteobacteria,1WXQX@135613|Chromatiales	135613|Chromatiales	L	DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
LZS2_k127_6252364_0	1171373.PACID_01150	3.472e-18	91.0	2DB83@1|root,2Z7Q0@2|Bacteria,2IAN4@201174|Actinobacteria,4DT7I@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4127
LZS2_k127_6252364_1	1514668.JOOA01000002_gene1493	1.204e-06	60.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3WH0E@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_6255464_1	1122135.KB893136_gene535	2.779e-05	55.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2U9FW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
LZS2_k127_6255464_0	30611.ENSOGAP00000011757	8.945e-17	91.0	COG0295@1|root,KOG0833@2759|Eukaryota,3A5YV@33154|Opisthokonta,3BSRU@33208|Metazoa,3D6BD@33213|Bilateria,481Z8@7711|Chordata,49AXA@7742|Vertebrata,3JGN5@40674|Mammalia,35PYP@314146|Euarchontoglires,4MJ0W@9443|Primates	33208|Metazoa	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	CDA	GO:0001558,GO:0001775,GO:0001882,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006140,GO:0006206,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009120,GO:0009163,GO:0009164,GO:0009451,GO:0009790,GO:0009792,GO:0009892,GO:0009972,GO:0009987,GO:0010563,GO:0012505,GO:0016043,GO:0016070,GO:0016192,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019239,GO:0019438,GO:0019439,GO:0019858,GO:0022607,GO:0023052,GO:0030141,GO:0030308,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032501,GO:0032502,GO:0032940,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0034774,GO:0036094,GO:0036230,GO:0040008,GO:0042119,GO:0042454,GO:0042455,GO:0042802,GO:0042803,GO:0043094,GO:0043097,GO:0043167,GO:0043169,GO:0043170,GO:0043174,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045926,GO:0045934,GO:0045936,GO:0045980,GO:0046087,GO:0046092,GO:0046108,GO:0046109,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046132,GO:0046133,GO:0046134,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046903,GO:0046914,GO:0046983,GO:0047844,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055086,GO:0060205,GO:0062012,GO:0062014,GO:0065003,GO:0065007,GO:0070013,GO:0070820,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659,GO:1904724,GO:1904813	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
LZS2_k127_6270820_0	1329516.JPST01000014_gene467	7.394e-24	106.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,27C8S@186824|Thermoactinomycetaceae	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
LZS2_k127_6270820_1	1268240.ATFI01000009_gene1633	1.215e-21	104.0	COG1285@1|root,COG1285@2|Bacteria,4NM47@976|Bacteroidetes,2FP38@200643|Bacteroidia,4AMD8@815|Bacteroidaceae	976|Bacteroidetes	S	Mg2 transporter-C family protein	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
LZS2_k127_6272727_1	324057.Pjdr2_1478	8.684e-61	234.0	COG0515@1|root,COG0515@2|Bacteria	324057.Pjdr2_1478|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6272727_0	290512.Paes_0605	8.482e-164	535.0	COG3930@1|root,COG3930@2|Bacteria,1FECR@1090|Chlorobi	1090|Chlorobi	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
LZS2_k127_6278132_1	555779.Dthio_PD1090	1.9e-20	100.0	COG0534@1|root,COG0534@2|Bacteria,1NS6X@1224|Proteobacteria,42MWN@68525|delta/epsilon subdivisions,2WMPY@28221|Deltaproteobacteria,2M9QH@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	PFAM Multi antimicrobial extrusion protein MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
LZS2_k127_6278132_2	1356852.N008_21740	1.169e-05	57.0	2CS7S@1|root,32SQK@2|Bacteria,4P1MR@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6278132_0	1117379.BABA_23990	7.787e-82	279.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
LZS2_k127_6282558_0	1123072.AUDH01000001_gene3112	5.212e-14	85.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2TV6U@28211|Alphaproteobacteria,2JQ9F@204441|Rhodospirillales	204441|Rhodospirillales	I	Lysophospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_62828_0	1123288.SOV_4c04750	1.333e-94	318.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4H34E@909932|Negativicutes	909932|Negativicutes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS2_k127_62828_2	362663.ECP_0242	6.959e-14	85.0	COG3210@1|root,COG3271@1|root,COG4104@1|root,COG3210@2|Bacteria,COG3271@2|Bacteria,COG4104@2|Bacteria	2|Bacteria	T	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3335,PAAR_motif,Peptidase_C39,Peptidase_C39_2,RHS,RHS_repeat,TPR_16,TPR_19,TPR_2,TPR_8
LZS2_k127_62828_1	1347369.CCAD010000056_gene4367	2.847e-61	226.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,1ZMP7@1386|Bacillus	91061|Bacilli	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS2_k127_6290983_0	321327.CYA_1968	2.12e-186	634.0	COG2373@1|root,COG2373@2|Bacteria,1G1A1@1117|Cyanobacteria,1H0M9@1129|Synechococcus	1117|Cyanobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,CarboxypepD_reg,MG1,Thiol-ester_cl
LZS2_k127_6293453_2	706587.Desti_2586	5.203e-51	186.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42TPX@68525|delta/epsilon subdivisions,2WNCR@28221|Deltaproteobacteria,2MSFN@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
LZS2_k127_6293453_7	237368.SCABRO_03844	1.09e-07	61.0	29C7G@1|root,2ZZ61@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6293453_0	344747.PM8797T_11621	1.852e-256	795.0	COG0076@1|root,COG0076@2|Bacteria,2J2HP@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the group II decarboxylase family	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
LZS2_k127_6293453_6	428127.EUBDOL_01029	4.08e-18	88.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,3VQ41@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Response regulator receiver domain protein	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_6293453_3	1396858.Q666_07185	9.7e-48	191.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,1RR1M@1236|Gammaproteobacteria,46630@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Response_reg
LZS2_k127_6293453_1	59374.Fisuc_1150	1.635e-109	364.0	COG0418@1|root,COG0418@2|Bacteria	2|Bacteria	F	dihydroorotase activity	pyrC	GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS2_k127_6293453_4	264198.Reut_A2231	1.081e-36	146.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,1K0S5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	UPF0114 protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
LZS2_k127_6293453_5	1545915.JROG01000007_gene3017	3.789e-34	137.0	COG0659@1|root,COG0659@2|Bacteria,1MX8F@1224|Proteobacteria,2U0IJ@28211|Alphaproteobacteria,2K0EC@204457|Sphingomonadales	204457|Sphingomonadales	P	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2,Sulfate_transp
LZS2_k127_6298265_0	649747.HMPREF0083_05440	2.297e-194	617.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26R6D@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	dhaS	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_6298265_1	1236542.BALM01000031_gene1881	8.773e-15	86.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,2Q961@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS2_k127_6321296_3	1144342.PMI40_04110	2.067e-05	55.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,472WP@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
LZS2_k127_6321296_4	713586.KB900536_gene2178	2.755e-05	55.0	COG3230@1|root,COG3230@2|Bacteria,1N9VG@1224|Proteobacteria,1S6DJ@1236|Gammaproteobacteria,1WYNE@135613|Chromatiales	135613|Chromatiales	P	PFAM Heme	-	-	-	-	-	-	-	-	-	-	-	-	Heme_oxygenase
LZS2_k127_6321296_1	1501230.ET33_31970	1.049e-68	253.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
LZS2_k127_6321296_2	1396141.BATP01000060_gene4562	1.509e-19	100.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,46VXM@74201|Verrucomicrobia,2IVSH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
LZS2_k127_6321296_0	272134.KB731324_gene2413	2.883e-148	477.0	COG0192@1|root,COG0192@2|Bacteria,1G0KW@1117|Cyanobacteria,1H7FK@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.metX	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
LZS2_k127_6330221_2	485918.Cpin_3698	3.315e-07	56.0	28ID8@1|root,2Z8FH@2|Bacteria,4NNKD@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6330221_1	189753.AXAS01000004_gene956	2.259e-34	144.0	COG0457@1|root,COG0457@2|Bacteria,1NG0U@1224|Proteobacteria,2U0YA@28211|Alphaproteobacteria,3K0QN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_6330221_0	997346.HMPREF9374_3153	9.77e-86	294.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli,27BAK@186824|Thermoactinomycetaceae	91061|Bacilli	S	Radical_SAM C-terminal domain	ytqA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
LZS2_k127_6330221_4	1408444.JHYC01000008_gene1427	3.549e-06	49.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6330221_3	332101.JIBU02000009_gene733	1.125e-06	61.0	COG0745@1|root,COG1215@1|root,COG0745@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	AtCs1C4	-	2.4.1.336	ko:K19003,ko:K20327	ko00561,ko01100,ko02024,map00561,map01100,map02024	-	R02689	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,T2SSE_N
LZS2_k127_6331636_2	478741.JAFS01000002_gene579	4.696e-28	119.0	COG0702@1|root,COG0702@2|Bacteria,46TAG@74201|Verrucomicrobia,37GJD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	GM	NAD(P)H-binding	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
LZS2_k127_6331636_3	521674.Plim_2804	4.367e-07	57.0	2EN1V@1|root,33FQ2@2|Bacteria,2J1CQ@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
LZS2_k127_6331636_1	1210884.HG799462_gene7940	1.249e-45	178.0	COG0451@1|root,COG0451@2|Bacteria,2IYS9@203682|Planctomycetes	203682|Planctomycetes	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS2_k127_6331636_0	1117314.PCIT_13169	8.477e-48	180.0	COG3568@1|root,COG3568@2|Bacteria,1R3X8@1224|Proteobacteria,1RZYH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
LZS2_k127_63353_2	551115.Aazo_1900	1.854e-05	55.0	COG1589@1|root,COG1589@2|Bacteria,1G29V@1117|Cyanobacteria,1HJ2J@1161|Nostocales	1117|Cyanobacteria	D	cell division	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
LZS2_k127_63353_0	471223.GWCH70_0053	2.935e-67	239.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,4HA0A@91061|Bacilli,1WFQ2@129337|Geobacillus	91061|Bacilli	S	MazG nucleotide pyrophosphohydrolase domain	yabN	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
LZS2_k127_63353_1	321327.CYA_0485	9.903e-66	231.0	COG1004@1|root,COG1004@2|Bacteria,1G1GI@1117|Cyanobacteria,1GYHC@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS2_k127_6341092_0	932213.SPM24T3_14486	1.434e-92	316.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	pltF	GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249	-	ko:K16126,ko:K21780	ko00333,ko01054,map00333,map01054	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
LZS2_k127_6341092_2	932213.SPM24T3_14491	5.394e-37	154.0	COG2263@1|root,COG2263@2|Bacteria,1NHD2@1224|Proteobacteria,1SIFM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6341092_1	932213.SPM24T3_14496	6.033e-88	302.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,400C8@613|Serratia	1236|Gammaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_6342195_0	1121920.AUAU01000008_gene1656	4.623e-05	51.0	COG1409@1|root,COG1409@2|Bacteria,3Y71A@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS2_k127_6342684_4	1089547.KB913013_gene2244	2.608e-10	68.0	COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,47MG0@768503|Cytophagia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PSCyt1
LZS2_k127_6342684_3	1408445.JHXP01000008_gene285	1.908e-14	79.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,1SEXH@1236|Gammaproteobacteria,1JEAJ@118969|Legionellales	118969|Legionellales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_6342684_1	329726.AM1_3296	2.222e-26	119.0	2DP0I@1|root,3301I@2|Bacteria,1G9UF@1117|Cyanobacteria	1117|Cyanobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
LZS2_k127_6342684_2	1120966.AUBU01000001_gene1204	3.09e-20	94.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,47N8G@768503|Cytophagia	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_8
LZS2_k127_6342684_0	237368.SCABRO_03546	1.604e-33	129.0	COG0376@1|root,COG0376@2|Bacteria,2IY35@203682|Planctomycetes	203682|Planctomycetes	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
LZS2_k127_6354485_0	316067.Geob_0847	1.64e-105	365.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,43T1F@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
LZS2_k127_6354485_2	1123288.SOV_5c02610	9.696e-17	91.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4H5IQ@909932|Negativicutes	909932|Negativicutes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
LZS2_k127_6354485_1	118168.MC7420_8054	1.353e-28	124.0	COG0457@1|root,COG0457@2|Bacteria,1G0N0@1117|Cyanobacteria,1HEV3@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_6356380_0	1443122.Z958_00185	1.992e-90	310.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,249IZ@186801|Clostridia,36FNG@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
LZS2_k127_6357636_0	204669.Acid345_1955	1.102e-75	267.0	COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria,2JK6X@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
LZS2_k127_6357636_1	13249.RPRC005352-PA	1.201e-11	69.0	KOG1037@1|root,KOG1037@2759|Eukaryota,38B7U@33154|Opisthokonta,3BBUM@33208|Metazoa,3CT5Y@33213|Bilateria,41VRJ@6656|Arthropoda,3SG42@50557|Insecta,3E9HS@33342|Paraneoptera	33208|Metazoa	KLO	Proposed nucleic acid binding domain	PARP1	GO:0000002,GO:0000003,GO:0000122,GO:0000166,GO:0000228,GO:0000302,GO:0000303,GO:0000305,GO:0000715,GO:0000723,GO:0000724,GO:0000725,GO:0000785,GO:0000790,GO:0000791,GO:0000976,GO:0000977,GO:0000981,GO:0001012,GO:0001067,GO:0001228,GO:0001817,GO:0001818,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002225,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002786,GO:0002791,GO:0002792,GO:0002803,GO:0002805,GO:0002807,GO:0002808,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003002,GO:0003006,GO:0003254,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003690,GO:0003700,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005667,GO:0005694,GO:0005700,GO:0005703,GO:0005719,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006140,GO:0006163,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006282,GO:0006284,GO:0006289,GO:0006293,GO:0006294,GO:0006296,GO:0006302,GO:0006310,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006471,GO:0006508,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006963,GO:0006974,GO:0006979,GO:0006996,GO:0006997,GO:0007000,GO:0007005,GO:0007154,GO:0007163,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007389,GO:0007552,GO:0007610,GO:0008069,GO:0008104,GO:0008134,GO:0008150,GO:0008152,GO:0008219,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009266,GO:0009303,GO:0009314,GO:0009408,GO:0009410,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009798,GO:0009888,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009950,GO:0009953,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010043,GO:0010212,GO:0010243,GO:0010332,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010611,GO:0010613,GO:0010628,GO:0010629,GO:0010639,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010990,GO:0012501,GO:0012505,GO:0014070,GO:0014742,GO:0014743,GO:0015030,GO:0016043,GO:0016070,GO:0016072,GO:0016333,GO:0016334,GO:0016485,GO:0016540,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0017144,GO:0018130,GO:0018193,GO:0018209,GO:0018312,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019899,GO:0019900,GO:0019901,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0022616,GO:0023019,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030225,GO:0030331,GO:0030534,GO:0030575,GO:0030576,GO:0030707,GO:0030808,GO:0030809,GO:0030855,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031334,GO:0031347,GO:0031349,GO:0031960,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032042,GO:0032101,GO:0032103,GO:0032200,GO:0032204,GO:0032205,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032660,GO:0032700,GO:0032774,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032991,GO:0032993,GO:0033036,GO:0033043,GO:0033044,GO:0033143,GO:0033145,GO:0033146,GO:0033148,GO:0033365,GO:0033554,GO:0033683,GO:0033993,GO:0034248,GO:0034250,GO:0034504,GO:0034599,GO:0034605,GO:0034613,GO:0034614,GO:0034622,GO:0034641,GO:0034644,GO:0034645,GO:0034654,GO:0034660,GO:0035079,GO:0035080,GO:0035257,GO:0035258,GO:0035363,GO:0036094,GO:0036211,GO:0040008,GO:0040009,GO:0042220,GO:0042221,GO:0042391,GO:0042393,GO:0042493,GO:0042592,GO:0042769,GO:0042802,GO:0042826,GO:0042981,GO:0043067,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043279,GO:0043388,GO:0043412,GO:0043434,GO:0043484,GO:0043502,GO:0043504,GO:0043523,GO:0043565,GO:0043900,GO:0043902,GO:0043933,GO:0044030,GO:0044057,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0044703,GO:0045087,GO:0045185,GO:0045595,GO:0045597,GO:0045739,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045944,GO:0045980,GO:0046034,GO:0046332,GO:0046483,GO:0047485,GO:0048037,GO:0048148,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048545,GO:0048583,GO:0048584,GO:0048609,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050707,GO:0050708,GO:0050709,GO:0050710,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050879,GO:0050881,GO:0050882,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051052,GO:0051053,GO:0051054,GO:0051094,GO:0051098,GO:0051099,GO:0051101,GO:0051103,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0051287,GO:0051385,GO:0051427,GO:0051457,GO:0051604,GO:0051606,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051881,GO:0051900,GO:0051901,GO:0055086,GO:0060249,GO:0060255,GO:0060341,GO:0060359,GO:0060390,GO:0060391,GO:0060429,GO:0062012,GO:0062014,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070212,GO:0070412,GO:0070727,GO:0070848,GO:0070887,GO:0070911,GO:0071214,GO:0071241,GO:0071248,GO:0071294,GO:0071310,GO:0071363,GO:0071375,GO:0071417,GO:0071450,GO:0071451,GO:0071478,GO:0071482,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0071824,GO:0071840,GO:0072347,GO:0072521,GO:0072595,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090092,GO:0090100,GO:0090257,GO:0090304,GO:0090305,GO:0097159,GO:0097305,GO:0097659,GO:0098687,GO:0098781,GO:0104004,GO:0140096,GO:0140097,GO:0140110,GO:1900180,GO:1900182,GO:1900371,GO:1900372,GO:1900407,GO:1900424,GO:1900426,GO:1900542,GO:1900543,GO:1901135,GO:1901214,GO:1901216,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901652,GO:1901653,GO:1901654,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902175,GO:1902531,GO:1902679,GO:1902680,GO:1902882,GO:1903201,GO:1903203,GO:1903376,GO:1903506,GO:1903507,GO:1903508,GO:1903516,GO:1903518,GO:1903530,GO:1903531,GO:1903578,GO:1903579,GO:1903827,GO:1903829,GO:1904044,GO:1904181,GO:1904356,GO:1904357,GO:1904645,GO:1904646,GO:1904760,GO:1904762,GO:1904950,GO:1905076,GO:1905077,GO:1990404,GO:1990837,GO:1990966,GO:2000112,GO:2000113,GO:2000677,GO:2000679,GO:2001020,GO:2001022,GO:2001141,GO:2001169,GO:2001170,GO:2001233,GO:2001242,GO:2001251	2.4.2.30	ko:K10798	ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217	M00296	-	-	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400	-	-	-	BRCT,PADR1,PARP,PARP_reg,WGR,zf-PARP
LZS2_k127_6378488_0	946362.XP_004992180.1	7.344e-42	156.0	COG0251@1|root,KOG2317@2759|Eukaryota,3A5RT@33154|Opisthokonta	33154|Opisthokonta	J	xenon atom binding	HRSP12	GO:0001505,GO:0001655,GO:0001822,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005504,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005759,GO:0005777,GO:0005829,GO:0006082,GO:0006139,GO:0006412,GO:0006417,GO:0006457,GO:0006518,GO:0006520,GO:0006544,GO:0006549,GO:0006566,GO:0006567,GO:0006725,GO:0006807,GO:0007049,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0008285,GO:0008289,GO:0008652,GO:0009056,GO:0009058,GO:0009059,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009081,GO:0009082,GO:0009097,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016054,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0017144,GO:0017148,GO:0019222,GO:0019239,GO:0019518,GO:0019538,GO:0019752,GO:0022402,GO:0030323,GO:0030324,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032543,GO:0033293,GO:0033993,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0035295,GO:0036041,GO:0036094,GO:0042127,GO:0042133,GO:0042221,GO:0042579,GO:0042737,GO:0042802,GO:0042803,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048513,GO:0048519,GO:0048523,GO:0048731,GO:0048856,GO:0050678,GO:0050680,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0060322,GO:0060541,GO:0065007,GO:0065008,GO:0070013,GO:0070314,GO:0071704,GO:0072001,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140053,GO:0140098,GO:1901360,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1902074,GO:1904012,GO:1904013,GO:2000112,GO:2000113	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS2_k127_6378488_2	1232437.KL661959_gene3101	3.107e-18	93.0	COG1989@1|root,COG1989@2|Bacteria,1R34X@1224|Proteobacteria,42V6M@68525|delta/epsilon subdivisions,2WRP6@28221|Deltaproteobacteria,2MKX4@213118|Desulfobacterales	28221|Deltaproteobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
LZS2_k127_6378488_1	1089553.Tph_c05530	9.981e-21	95.0	COG1430@1|root,COG1430@2|Bacteria,1VF55@1239|Firmicutes,24QZ4@186801|Clostridia,42H4S@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
LZS2_k127_6378488_3	1121459.AQXE01000020_gene762	6.575e-11	68.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,42R2X@68525|delta/epsilon subdivisions,2WMU1@28221|Deltaproteobacteria,2MAZ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS2_k127_6380677_4	1392488.JHZY01000002_gene1050	1.167e-19	88.0	COG0636@1|root,COG0636@2|Bacteria,4NSX1@976|Bacteroidetes	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
LZS2_k127_6380677_3	1267535.KB906767_gene2878	1.236e-35	144.0	COG0711@1|root,COG0711@2|Bacteria,3Y8BU@57723|Acidobacteria,2JN51@204432|Acidobacteriia	204432|Acidobacteriia	C	ATP synthase B/B' CF(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
LZS2_k127_6380677_0	1122207.MUS1_07790	9.899e-177	567.0	COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,1RMVT@1236|Gammaproteobacteria,1XI90@135619|Oceanospirillales	135619|Oceanospirillales	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA1	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS2_k127_6380677_2	1150600.ADIARSV_0086	2.095e-52	196.0	COG0224@1|root,COG0224@2|Bacteria,4NJ5J@976|Bacteroidetes,1IY1B@117747|Sphingobacteriia	976|Bacteroidetes	C	ATP synthase	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
LZS2_k127_6380677_1	1280949.HAD_09775	2.482e-82	278.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
LZS2_k127_6398307_0	136037.KDR15061	2.575e-115	389.0	COG0308@1|root,KOG1046@2759|Eukaryota,38CFG@33154|Opisthokonta,3BADC@33208|Metazoa,3CW5S@33213|Bilateria,41WW7@6656|Arthropoda,3SGEA@50557|Insecta	33208|Metazoa	O	zinc ion binding. It is involved in the biological process described with proteolysis	NPEPPS	GO:0000003,GO:0000209,GO:0000578,GO:0000793,GO:0000922,GO:0001666,GO:0003002,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005819,GO:0005829,GO:0005856,GO:0006464,GO:0006508,GO:0006518,GO:0006807,GO:0006950,GO:0007049,GO:0007275,GO:0007350,GO:0007351,GO:0007389,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008595,GO:0009056,GO:0009628,GO:0009790,GO:0009792,GO:0009798,GO:0009880,GO:0009948,GO:0009952,GO:0009987,GO:0010564,GO:0010720,GO:0015630,GO:0016567,GO:0016787,GO:0019538,GO:0022402,GO:0022414,GO:0030588,GO:0030590,GO:0032446,GO:0032501,GO:0032502,GO:0033218,GO:0033554,GO:0034641,GO:0035282,GO:0036211,GO:0036293,GO:0036294,GO:0042221,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043603,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044771,GO:0045595,GO:0045597,GO:0046662,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050896,GO:0051094,GO:0051179,GO:0051235,GO:0051239,GO:0051240,GO:0051321,GO:0051445,GO:0051640,GO:0051641,GO:0051642,GO:0051651,GO:0051657,GO:0051661,GO:0051716,GO:0051726,GO:0060281,GO:0060282,GO:0060284,GO:0061842,GO:0065007,GO:0065008,GO:0070006,GO:0070011,GO:0070482,GO:0070647,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0072686,GO:0097431,GO:0140096,GO:1900193,GO:1900195,GO:1901564,GO:1901565,GO:1901575,GO:1903046,GO:1903429,GO:1903431,GO:1903538,GO:1905879,GO:1905881,GO:1990947,GO:2000241,GO:2000243	-	ko:K08776	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
LZS2_k127_6398307_1	234267.Acid_7272	3.572e-41	155.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,3Y2IR@57723|Acidobacteria	57723|Acidobacteria	P	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
LZS2_k127_6404132_1	1519464.HY22_13825	8.395e-68	233.0	COG0345@1|root,COG0345@2|Bacteria,1FE2A@1090|Chlorobi	1090|Chlorobi	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
LZS2_k127_6404132_2	595460.RRSWK_01903	1.859e-07	62.0	COG4886@1|root,COG4886@2|Bacteria,2IZVQ@203682|Planctomycetes	203682|Planctomycetes	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6404132_0	1005048.CFU_3219	3.562e-189	599.0	COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,2VJUH@28216|Betaproteobacteria,4728F@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
LZS2_k127_6404132_3	1128398.Curi_c04860	3.847e-06	53.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,26ADI@186813|unclassified Clostridiales	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_641171_0	862908.BMS_0905	2.437e-156	507.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,42N9T@68525|delta/epsilon subdivisions,2WPH6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
LZS2_k127_641171_1	688270.Celal_1376	5.383e-61	225.0	COG0530@1|root,COG0530@2|Bacteria,4PIPH@976|Bacteroidetes,1IH2R@117743|Flavobacteriia,1FAAU@104264|Cellulophaga	976|Bacteroidetes	P	PFAM Sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS2_k127_6416327_1	1120973.AQXL01000135_gene1317	1.886e-36	143.0	COG1659@1|root,COG1659@2|Bacteria,1UR7R@1239|Firmicutes,4HCW3@91061|Bacilli	91061|Bacilli	S	Encapsulating protein for peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Linocin_M18
LZS2_k127_6416327_0	195253.Syn6312_0622	1.65e-50	190.0	COG1398@1|root,COG1398@2|Bacteria,1G100@1117|Cyanobacteria,1GYSI@1129|Synechococcus	1117|Cyanobacteria	I	desaturase	ole1	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS2_k127_6420362_3	1120999.JONM01000022_gene3309	1.247e-12	70.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2VTSH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
LZS2_k127_6420362_0	485913.Krac_11908	8.547e-83	287.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS2_k127_6420362_4	1267533.KB906734_gene4044	3.611e-12	77.0	COG1725@1|root,COG1725@2|Bacteria,3Y5VN@57723|Acidobacteria,2JK5T@204432|Acidobacteriia	2|Bacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07978,ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
LZS2_k127_6420362_2	338963.Pcar_1754	2.621e-29	128.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,42R2X@68525|delta/epsilon subdivisions,2WMU1@28221|Deltaproteobacteria,43UHH@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS2_k127_6420362_1	1120985.AUMI01000014_gene1067	1.601e-33	141.0	COG4965@1|root,COG4965@2|Bacteria,1UZ3V@1239|Firmicutes,4H3YR@909932|Negativicutes	909932|Negativicutes	U	Type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS2_k127_6420715_3	977880.pRALTA_0340	8.835e-05	48.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,2VMZS@28216|Betaproteobacteria,1K35W@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	rve
LZS2_k127_6420715_1	306281.AJLK01000150_gene1957	1.036e-30	123.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	AAA,ClpS
LZS2_k127_6420715_2	1183438.GKIL_0683	4.706e-06	51.0	COG0810@1|root,COG1714@1|root,COG0810@2|Bacteria,COG1714@2|Bacteria,1GQMS@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM TonB family C-terminal domain	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	RDD,TonB_2
LZS2_k127_6420715_0	479434.Sthe_1246	8.267e-42	173.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi,27Z13@189775|Thermomicrobia	189775|Thermomicrobia	KLT	PQQ-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
LZS2_k127_6420790_2	1159870.KB907784_gene768	1.184e-15	81.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	CbiA,GATase_3
LZS2_k127_6420790_1	1382358.JHVN01000014_gene1669	5.257e-22	104.0	COG2042@1|root,COG3376@2|Bacteria,1VDYF@1239|Firmicutes,4HM2T@91061|Bacilli	91061|Bacilli	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	NicO
LZS2_k127_6420790_0	313612.L8106_06674	7.224e-95	330.0	COG0405@1|root,COG0405@2|Bacteria,1G20A@1117|Cyanobacteria,1H8BE@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS2_k127_6421812_0	1121930.AQXG01000002_gene1988	1.178e-39	152.0	COG0739@1|root,COG0739@2|Bacteria,4NPNT@976|Bacteroidetes	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_6422035_1	330214.NIDE0965	2.668e-67	242.0	COG0429@1|root,COG0429@2|Bacteria	2|Bacteria	S	poly(3-hydroxybutyrate) depolymerase activity	-	GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
LZS2_k127_6422035_0	743722.Sph21_2570	5.921e-138	449.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,1IQZ0@117747|Sphingobacteriia	976|Bacteroidetes	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
LZS2_k127_6422035_4	1173028.ANKO01000190_gene439	1.193e-14	88.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H6WA@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_6422035_2	536232.CLM_2978	5.956e-36	149.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,24AGI@186801|Clostridia,36EXT@31979|Clostridiaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
LZS2_k127_6422035_3	926559.JoomaDRAFT_3463	2.958e-27	116.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1I30U@117743|Flavobacteriia	976|Bacteroidetes	S	Thiol-disulfide oxidoreductase	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
LZS2_k127_6422389_0	554065.XP_005843969.1	1.497e-64	225.0	COG0221@1|root,KOG1626@2759|Eukaryota,37R74@33090|Viridiplantae,34J91@3041|Chlorophyta	3041|Chlorophyta	C	soluble inorganic pyrophosphatase	-	GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
LZS2_k127_6422389_2	36809.MAB_0033c	8.665e-53	211.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,233BZ@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_6422389_1	164757.Mjls_0015	1.564e-53	209.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,233BZ@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_6427229_0	1163407.UU7_14043	1.061e-68	241.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,1X3KQ@135614|Xanthomonadales	135614|Xanthomonadales	P	membrane protein terc	-	-	-	-	-	-	-	-	-	-	-	-	TerC
LZS2_k127_6427229_1	1408473.JHXO01000005_gene1608	2.956e-13	71.0	COG0412@1|root,COG0412@2|Bacteria,4NKMA@976|Bacteroidetes,2FTW8@200643|Bacteroidia	976|Bacteroidetes	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
LZS2_k127_6432929_1	946483.Cenrod_1414	4.807e-06	51.0	COG3636@1|root,COG3636@2|Bacteria,1N0RK@1224|Proteobacteria,2VTIU@28216|Betaproteobacteria,4AF8F@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6432929_0	240292.Ava_4492	1.645e-13	83.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_6434333_0	10224.XP_002736294.1	2.649e-24	107.0	2957P@1|root,2RC5J@2759|Eukaryota,39VX7@33154|Opisthokonta,3BC8N@33208|Metazoa,3CSBH@33213|Bilateria	33208|Metazoa	S	Nucleoside 2-deoxyribosyltransferase like	-	GO:0000003,GO:0000902,GO:0001655,GO:0001700,GO:0001932,GO:0001933,GO:0002009,GO:0003006,GO:0003008,GO:0005575,GO:0005623,GO:0005886,GO:0007275,GO:0007390,GO:0007391,GO:0007392,GO:0007394,GO:0007399,GO:0007417,GO:0007422,GO:0007431,GO:0007435,GO:0007439,GO:0007442,GO:0007443,GO:0007548,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008306,GO:0008355,GO:0008360,GO:0008406,GO:0009653,GO:0009790,GO:0009792,GO:0009826,GO:0009887,GO:0009888,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010563,GO:0010605,GO:0010646,GO:0010648,GO:0016020,GO:0016043,GO:0016049,GO:0016331,GO:0016476,GO:0019220,GO:0019222,GO:0022414,GO:0022603,GO:0022604,GO:0022612,GO:0023051,GO:0023057,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032872,GO:0032873,GO:0032989,GO:0033036,GO:0035150,GO:0035239,GO:0035262,GO:0035272,GO:0035295,GO:0035296,GO:0035297,GO:0035298,GO:0040007,GO:0042048,GO:0042221,GO:0042325,GO:0042326,GO:0043408,GO:0043409,GO:0044464,GO:0045137,GO:0045936,GO:0045995,GO:0046328,GO:0046329,GO:0048513,GO:0048519,GO:0048523,GO:0048546,GO:0048565,GO:0048567,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048608,GO:0048619,GO:0048729,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051239,GO:0051246,GO:0051248,GO:0055123,GO:0060255,GO:0060429,GO:0060560,GO:0060562,GO:0061326,GO:0061333,GO:0061458,GO:0061525,GO:0065007,GO:0065008,GO:0070302,GO:0070303,GO:0071840,GO:0071944,GO:0072001,GO:0072002,GO:0080090,GO:0080134,GO:0080135,GO:0090066,GO:1902531,GO:1902532,GO:2000026	-	ko:K20235	ko04013,map04013	-	-	-	ko00000,ko00001	-	-	-	Nuc_deoxyri_tr2
LZS2_k127_6434333_2	113355.CM001775_gene2675	9.024e-12	79.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	113355.CM001775_gene2675|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6434333_1	536227.CcarbDRAFT_5161	3.104e-19	103.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,36FCZ@31979|Clostridiaceae	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
LZS2_k127_6434822_0	266117.Rxyl_0101	3.237e-64	231.0	COG1266@1|root,COG1266@2|Bacteria,2GMJ1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS2_k127_6434822_1	1210884.HG799469_gene14122	1.533e-33	144.0	COG5183@1|root,COG5183@2|Bacteria,2IX3Y@203682|Planctomycetes	203682|Planctomycetes	A	protein ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6434822_2	344747.PM8797T_27664	4.755e-31	133.0	COG4319@1|root,COG4319@2|Bacteria,2IZWW@203682|Planctomycetes	203682|Planctomycetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
LZS2_k127_6434822_3	485918.Cpin_6051	8.174e-15	86.0	COG0526@1|root,COG0526@2|Bacteria,4NSY5@976|Bacteroidetes	976|Bacteroidetes	CO	thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
LZS2_k127_6453383_1	246194.CHY_1769	1.549e-102	346.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,42EQU@68295|Thermoanaerobacterales	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
LZS2_k127_6453383_4	292459.STH1520	3.019e-05	51.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia	186801|Clostridia	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
LZS2_k127_6453383_0	273068.TTE1393	1.461e-184	612.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,42EP2@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
LZS2_k127_6453383_2	1449126.JQKL01000001_gene1379	5.328e-25	108.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,2692J@186813|unclassified Clostridiales	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
LZS2_k127_6453383_3	329726.AM1_3004	3.03e-22	96.0	COG0130@1|root,COG0130@2|Bacteria,1G0S5@1117|Cyanobacteria	1117|Cyanobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
LZS2_k127_6456987_0	756067.MicvaDRAFT_2472	1.486e-78	273.0	COG0477@1|root,COG2814@2|Bacteria,1G1K4@1117|Cyanobacteria,1H9RK@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major facilitator superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
LZS2_k127_6456987_1	1173023.KE650771_gene4700	1.037e-53	205.0	COG0793@1|root,COG0793@2|Bacteria,1G30Q@1117|Cyanobacteria,1JJ6B@1189|Stigonemataceae	1117|Cyanobacteria	M	Tricorn protease C1 domain	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
LZS2_k127_6469516_2	1444309.JAQG01000057_gene4893	1.747e-08	56.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,26QGD@186822|Paenibacillaceae	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
LZS2_k127_6469516_1	398767.Glov_0671	2.357e-72	260.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,43TAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
LZS2_k127_6469516_0	555079.Toce_0950	3.075e-97	334.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS2_k127_6488853_0	497964.CfE428DRAFT_1140	5.184e-87	293.0	COG1611@1|root,COG1611@2|Bacteria,46SEG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Possible lysine decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lysine_decarbox
LZS2_k127_6492306_0	118005.AWNK01000009_gene241	9.979e-15	83.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	iIT341.HP0814	ThiF
LZS2_k127_6496134_4	530564.Psta_3139	1.156e-21	96.0	COG0235@1|root,COG0235@2|Bacteria,2J2P1@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	4.2.1.109	ko:K08964	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
LZS2_k127_6496134_0	530564.Psta_3140	1.148e-74	256.0	COG1791@1|root,COG1791@2|Bacteria,2J2NB@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
LZS2_k127_6496134_1	314230.DSM3645_20377	2.589e-65	231.0	COG4229@1|root,COG4229@2|Bacteria,2J2V4@203682|Planctomycetes	203682|Planctomycetes	H	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)	mtnC	-	3.1.3.77	ko:K09880	ko00270,ko01100,map00270,map01100	M00034	R07395	RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	-
LZS2_k127_6496134_5	1280706.AUJE01000011_gene540	2.104e-15	90.0	COG5263@1|root,COG5263@2|Bacteria,1V30N@1239|Firmicutes,4H8HT@909932|Negativicutes	909932|Negativicutes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6496134_2	572477.Alvin_2655	1.207e-31	143.0	COG4932@1|root,COG4932@2|Bacteria,1NHC4@1224|Proteobacteria,1SUN7@1236|Gammaproteobacteria,1X207@135613|Chromatiales	135613|Chromatiales	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
LZS2_k127_6496134_3	1232437.KL662076_gene3460	4.374e-27	128.0	COG4249@1|root,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions,2WSC3@28221|Deltaproteobacteria,2MN4H@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TIR_2,WD40
LZS2_k127_6496271_2	985867.AEWF01000006_gene637	2.691e-16	80.0	2EJHZ@1|root,31BC0@2|Bacteria,1Q76N@1224|Proteobacteria,2UXAN@28211|Alphaproteobacteria,47FUI@766|Rickettsiales	766|Rickettsiales	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
LZS2_k127_6496271_1	243231.GSU3596	7.16e-31	135.0	COG3755@1|root,COG3755@2|Bacteria,1QXPQ@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LprI
LZS2_k127_6496271_0	198467.NP92_06205	1.654e-102	342.0	COG1715@1|root,COG1715@2|Bacteria,1V1TA@1239|Firmicutes,4HC3T@91061|Bacilli	91061|Bacilli	L	restriction endonuclease	mrr2	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	MerR_1,Mrr_N,Mrr_cat
LZS2_k127_6496271_3	326427.Cagg_3818	2.915e-12	79.0	COG3703@1|root,COG3703@2|Bacteria,2GBRN@200795|Chloroflexi,376AK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2
LZS2_k127_6496271_4	1230343.CANP01000031_gene2336	9.207e-05	55.0	2AP7V@1|root,31E9Q@2|Bacteria,1QBJC@1224|Proteobacteria,1T74Z@1236|Gammaproteobacteria,1JEW6@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6501930_0	1192034.CAP_6321	2.03e-51	203.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YYKD@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
LZS2_k127_6508756_0	1131269.AQVV01000001_gene1406	7.621e-76	272.0	COG0404@1|root,COG0457@1|root,COG3071@1|root,COG0404@2|Bacteria,COG0457@2|Bacteria,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	ygfZ	-	1.5.3.1,2.1.2.10,3.1.21.3	ko:K00305,ko:K00605,ko:K01153,ko:K02498,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R00610,R01221,R02300,R04125	RC00022,RC00060,RC00069,RC00183,RC00557,RC02834	ko00000,ko00001,ko00002,ko01000,ko02048,ko03016	-	-	-	DUF2905,GCV_T,GCV_T_C
LZS2_k127_6508756_1	313628.LNTAR_14867	9.488e-32	128.0	COG0316@1|root,COG0316@2|Bacteria	2|Bacteria	S	protein maturation	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
LZS2_k127_6509779_1	72019.SARC_05655T0	4.66e-11	65.0	COG0654@1|root,KOG2614@2759|Eukaryota,38H32@33154|Opisthokonta	33154|Opisthokonta	C	kynurenine 3-monooxygenase activity	BNA4	GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0004502,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009108,GO:0009117,GO:0009165,GO:0009267,GO:0009308,GO:0009435,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0016020,GO:0016174,GO:0016491,GO:0016651,GO:0016705,GO:0016709,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019748,GO:0019752,GO:0019867,GO:0030447,GO:0031090,GO:0031667,GO:0031668,GO:0031669,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0033554,GO:0034354,GO:0034627,GO:0034641,GO:0034654,GO:0036094,GO:0036170,GO:0036180,GO:0040007,GO:0042180,GO:0042430,GO:0042537,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044182,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044550,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0050664,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0055114,GO:0070189,GO:0071496,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0098588,GO:0098805,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.14.13.9	ko:K00486	ko00380,ko01100,map00380,map01100	M00038	R01960	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
LZS2_k127_6509779_2	1120999.JONM01000004_gene3474	0.0003993	52.0	COG2199@1|root,COG3706@2|Bacteria,1R29F@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
LZS2_k127_6509779_0	215803.DB30_2128	1.671e-104	344.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,43475@68525|delta/epsilon subdivisions,2X27R@28221|Deltaproteobacteria,2YXCB@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	mocA	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_651124_0	240015.ACP_1130	2.355e-317	1003.0	COG0841@1|root,COG0841@2|Bacteria,3Y478@57723|Acidobacteria,2JP42@204432|Acidobacteriia	204432|Acidobacteriia	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS2_k127_651124_1	1267535.KB906767_gene2008	2.372e-66	243.0	COG0845@1|root,COG0845@2|Bacteria,3Y2U2@57723|Acidobacteria,2JMFW@204432|Acidobacteriia	204432|Acidobacteriia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS2_k127_651124_3	313606.M23134_06583	7.387e-07	62.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,47N11@768503|Cytophagia	976|Bacteroidetes	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12
LZS2_k127_651124_2	661478.OP10G_2113	1.111e-61	224.0	COG1222@1|root,COG1222@2|Bacteria	2|Bacteria	O	protein catabolic process	-	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,ClpS
LZS2_k127_6521452_2	402777.KB235903_gene2003	9.306e-23	107.0	2EK9W@1|root,33E06@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6521452_1	1173026.Glo7428_0510	2.502e-44	164.0	COG0154@1|root,COG0154@2|Bacteria,1G6Z8@1117|Cyanobacteria	1117|Cyanobacteria	J	amidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6521452_0	382464.ABSI01000011_gene3064	8.118e-73	254.0	COG4760@1|root,COG4760@2|Bacteria,46ZIY@74201|Verrucomicrobia,2IV4T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bax inhibitor 1 like	-	-	-	-	-	-	-	-	-	-	-	-	BaxI_1
LZS2_k127_6521452_3	903818.KI912268_gene3050	1.665e-18	89.0	COG0735@1|root,COG0735@2|Bacteria,3Y7UH@57723|Acidobacteria	57723|Acidobacteria	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS2_k127_6526532_0	290397.Adeh_2872	4.658e-21	97.0	2FCAT@1|root,344EF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6535398_0	1382304.JNIL01000001_gene670	2.573e-34	138.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_6535613_0	383372.Rcas_1495	2.123e-61	215.0	COG1051@1|root,COG1051@2|Bacteria,2G7HA@200795|Chloroflexi,3777X@32061|Chloroflexia	32061|Chloroflexia	F	PFAM NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS2_k127_6535613_1	448385.sce2470	3.058e-48	194.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
LZS2_k127_6535613_2	1000569.HMPREF1040_1233	7.884e-05	45.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_6538107_1	1166018.FAES_pFAES01145	2.505e-55	201.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	ybaS	-	1.1.1.58	ko:K00041,ko:K03453,ko:K14347	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000,ko02000,ko04147	2.A.28,2.A.93.1	-	-	SBF,SBF_like
LZS2_k127_6538107_0	935948.KE386494_gene725	6.245e-104	366.0	COG0497@1|root,COG0551@1|root,COG1112@1|root,COG0497@2|Bacteria,COG0551@2|Bacteria,COG1112@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia,42FR8@68295|Thermoanaerobacterales	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF559
LZS2_k127_6539756_2	246197.MXAN_7362	7.149e-30	127.0	COG0745@1|root,COG2199@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2X7CV@28221|Deltaproteobacteria,2YUZ7@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
LZS2_k127_6539756_1	745014.OMB55_00014950	6.665e-37	143.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_3
LZS2_k127_6539756_0	395961.Cyan7425_1362	4.438e-119	396.0	COG1574@1|root,COG1574@2|Bacteria,1G40U@1117|Cyanobacteria	1117|Cyanobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS2_k127_6546850_0	266835.14022787	2.102e-19	102.0	COG0457@1|root,COG0457@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria,43RSN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_6546850_1	396588.Tgr7_1050	3.531e-06	54.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RZ9I@1236|Gammaproteobacteria,1WWMR@135613|Chromatiales	135613|Chromatiales	I	PFAM Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
LZS2_k127_6567183_0	502025.Hoch_3876	5.044e-52	206.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions,2WJKQ@28221|Deltaproteobacteria,2YXDF@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,Pkinase
LZS2_k127_6567183_1	1210884.HG799463_gene9534	5.176e-45	187.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_6567183_2	1449126.JQKL01000006_gene780	1.99e-31	138.0	COG4872@1|root,COG4872@2|Bacteria,1TT9X@1239|Firmicutes,24CCI@186801|Clostridia,26CEA@186813|unclassified Clostridiales	186801|Clostridia	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
LZS2_k127_6567183_3	224911.27348653	3.097e-15	85.0	COG4929@1|root,COG4929@2|Bacteria,1NURJ@1224|Proteobacteria,2TV9N@28211|Alphaproteobacteria,3JWT3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
LZS2_k127_656874_0	221288.JH992901_gene2643	1.191e-32	141.0	COG0642@1|root,COG2205@2|Bacteria,1G06C@1117|Cyanobacteria,1JMWQ@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_65902_1	264462.Bd0255	3.441e-211	681.0	COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,42NV8@68525|delta/epsilon subdivisions,2WJIW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DEAD_2	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
LZS2_k127_65902_0	3067.XP_002958295.1	1.251e-231	736.0	COG0443@1|root,KOG0102@2759|Eukaryota,37IHK@33090|Viridiplantae,34IYM@3041|Chlorophyta	3041|Chlorophyta	O	Heat Shock Protein	HSP70B	-	-	ko:K03283	ko03040,ko04010,ko04141,ko04144,ko04213,ko04612,ko04915,ko05134,ko05145,ko05162,ko05164,ko05169,map03040,map04010,map04141,map04144,map04213,map04612,map04915,map05134,map05145,map05162,map05164,map05169	M00353,M00355	-	-	ko00000,ko00001,ko00002,ko01009,ko03009,ko03029,ko03041,ko03051,ko03110,ko04131,ko04147,ko04516	1.A.33.1	-	-	HSP70
LZS2_k127_6608855_0	1379270.AUXF01000001_gene2615	4.548e-69	248.0	COG0587@1|root,COG0587@2|Bacteria,1ZU9R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS2_k127_6608855_1	1173028.ANKO01000127_gene4196	1.489e-43	166.0	COG0500@1|root,COG0500@2|Bacteria,1G56P@1117|Cyanobacteria,1HAXF@1150|Oscillatoriales	1117|Cyanobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
LZS2_k127_6615225_3	1444309.JAQG01000065_gene2422	9.527e-05	48.0	COG4961@1|root,COG4961@2|Bacteria,1TZPI@1239|Firmicutes,4HRXM@91061|Bacilli	91061|Bacilli	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS2_k127_6615225_2	266117.Rxyl_3118	2.718e-80	279.0	COG1216@1|root,COG1216@2|Bacteria,2GK2D@201174|Actinobacteria,4CQ6N@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_6615225_1	1050202.KB913024_gene2729	7.1e-89	309.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2I28C@201174|Actinobacteria,407UH@622450|Actinopolysporales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_1
LZS2_k127_6615225_0	1191523.MROS_0406	1.467e-107	355.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2,Thioredoxin
LZS2_k127_6623997_0	1121342.AUCO01000017_gene2851	2.062e-124	408.0	COG1953@1|root,COG1953@2|Bacteria,1TS5W@1239|Firmicutes,247WK@186801|Clostridia,36VS3@31979|Clostridiaceae	186801|Clostridia	FH	PFAM Permease for cytosine purines, uracil, thiamine, allantoin	pucI	-	-	ko:K03457	-	-	-	-	ko00000	2.A.39	-	-	Transp_cyt_pur
LZS2_k127_6623997_1	937777.Deipe_2571	4.788e-20	102.0	COG1286@1|root,COG2340@1|root,COG1286@2|Bacteria,COG2340@2|Bacteria,1WK37@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
LZS2_k127_6625618_0	1283299.AUKG01000002_gene4594	2.211e-96	337.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4CPYZ@84995|Rubrobacteria	84995|Rubrobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DAO_C
LZS2_k127_6625618_1	1469607.KK073766_gene149	1.667e-10	72.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HIJM@1161|Nostocales	1117|Cyanobacteria	S	SPTR Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
LZS2_k127_6627975_0	1219581.HMPREF1628_04425	1.974e-17	86.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,4D52E@85005|Actinomycetales	201174|Actinobacteria	T	FHA domain protein	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
LZS2_k127_6627975_1	661478.OP10G_4286	1.564e-07	64.0	2EKVR@1|root,33EJ9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6642874_1	203119.Cthe_1162	2.897e-64	225.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3WGUC@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
LZS2_k127_6642874_2	1408424.JHYI01000001_gene1963	4.414e-59	211.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli,1ZAZF@1386|Bacillus	91061|Bacilli	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
LZS2_k127_6642874_0	555088.DealDRAFT_2403	1.068e-89	302.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,42JRN@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS2_k127_6642874_3	1123368.AUIS01000001_gene2037	1.744e-39	154.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,2NCQC@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
LZS2_k127_6663952_0	468059.AUHA01000006_gene2921	3.218e-137	451.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,1IPW4@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS2_k127_6663952_1	1343739.PAP_04850	5.501e-90	307.0	COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,242YC@183968|Thermococci	183968|Thermococci	E	GTPase activity	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
LZS2_k127_667667_0	661478.OP10G_0423	0.0	1052.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_6702389_1	570967.JMLV01000012_gene3211	2.512e-91	308.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,2JQQU@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_6702389_2	251221.35211799	5.218e-54	203.0	COG1398@1|root,COG1398@2|Bacteria,1G100@1117|Cyanobacteria	1117|Cyanobacteria	I	fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS2_k127_6702389_3	980584.AFPB01000183_gene904	3.941e-18	91.0	COG3911@1|root,COG3911@2|Bacteria,4NNT6@976|Bacteroidetes,1I25D@117743|Flavobacteriia,40756@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
LZS2_k127_6702389_0	3827.XP_004511739.1	1.762e-159	510.0	COG0334@1|root,KOG2250@2759|Eukaryota,37Q3I@33090|Viridiplantae,3GC9F@35493|Streptophyta,4JRW9@91835|fabids	35493|Streptophyta	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	GO:0000166,GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005773,GO:0005774,GO:0006950,GO:0006970,GO:0006995,GO:0007154,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009267,GO:0009268,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010446,GO:0016020,GO:0016491,GO:0016638,GO:0016639,GO:0017076,GO:0030554,GO:0031090,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0035639,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043562,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0051716,GO:0055114,GO:0071496,GO:0097159,GO:0097367,GO:0098588,GO:0098805,GO:1901265,GO:1901363	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_6716155_4	632292.Calhy_1954	4.514e-31	134.0	COG1409@1|root,COG1409@2|Bacteria,1VJ4D@1239|Firmicutes	1239|Firmicutes	S	Calcineurin-like phosphoesterase	-	-	3.1.4.17,3.1.4.53	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
LZS2_k127_6716155_3	1278073.MYSTI_08055	2.05e-58	213.0	COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,42YUJ@68525|delta/epsilon subdivisions,2WTUY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
LZS2_k127_6716155_2	391625.PPSIR1_39355	8.457e-65	247.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PP2C_2,Pkinase,TPR_12,TPR_8
LZS2_k127_6716155_1	1001585.MDS_1939	4.149e-92	306.0	2EIKC@1|root,33CBN@2|Bacteria,1NIFQ@1224|Proteobacteria,1T9G7@1236|Gammaproteobacteria,1YCVG@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6716155_6	379731.PST_1428	1.68e-11	69.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1S248@1236|Gammaproteobacteria,1Z0QU@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	COG2853 Surface lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
LZS2_k127_6716155_0	1395571.TMS3_0112880	8.501e-172	543.0	COG0697@1|root,COG0697@2|Bacteria,1PGSE@1224|Proteobacteria,1RMZY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	yhbE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_6716155_5	1215092.PA6_012_01040	1.22e-11	66.0	2CJRP@1|root,33F8D@2|Bacteria,1NMNN@1224|Proteobacteria,1SGVS@1236|Gammaproteobacteria,1YGYH@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6728970_1	745277.GRAQ_03978	2.244e-17	85.0	2E7TE@1|root,3328J@2|Bacteria,1N6RC@1224|Proteobacteria,1SDN2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
LZS2_k127_6728970_0	1267535.KB906767_gene1056	2.691e-127	416.0	COG0667@1|root,COG0667@2|Bacteria,3Y311@57723|Acidobacteria,2JIS2@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_6728970_3	1121007.AUML01000025_gene3	1.395e-06	51.0	COG5654@1|root,COG5654@2|Bacteria,4NQ91@976|Bacteroidetes,1I40X@117743|Flavobacteriia,2YHMW@290174|Aquimarina	976|Bacteroidetes	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
LZS2_k127_6728970_2	1123368.AUIS01000009_gene2437	1.633e-08	57.0	COG5642@1|root,COG5642@2|Bacteria,1RJWF@1224|Proteobacteria,1S8GN@1236|Gammaproteobacteria,2NE1Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
LZS2_k127_6728970_4	330214.NIDE1149	0.0003237	50.0	2EIBB@1|root,33C2R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6729077_4	583355.Caka_2119	1.245e-17	97.0	COG5316@1|root,COG5316@2|Bacteria,46YSV@74201|Verrucomicrobia,3K7S5@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
LZS2_k127_6729077_3	1499967.BAYZ01000088_gene5065	6.756e-22	101.0	COG2365@1|root,COG2365@2|Bacteria	2|Bacteria	T	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	DSPc,Y_phosphatase2,Y_phosphatase3
LZS2_k127_6729077_0	317619.ANKN01000191_gene560	9.229e-240	751.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1G06N@1117|Cyanobacteria,1MKN6@1212|Prochloraceae	1117|Cyanobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
LZS2_k127_6729077_2	338966.Ppro_2695	4.786e-26	124.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,42RRN@68525|delta/epsilon subdivisions,2WNAY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6729077_1	1173027.Mic7113_3146	2.447e-106	354.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
LZS2_k127_6736773_1	1242864.D187_010069	2.361e-23	112.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
LZS2_k127_6736773_2	1120966.AUBU01000010_gene2968	5.726e-21	105.0	COG2267@1|root,COG2267@2|Bacteria,4NQ59@976|Bacteroidetes,47R0A@768503|Cytophagia	976|Bacteroidetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_6736773_0	1123508.JH636439_gene603	5.509e-80	280.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	hetM	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,NAD_binding_4
LZS2_k127_6738411_2	883112.HMPREF9707_01013	4.456e-05	48.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes	1239|Firmicutes	E	ABC transporter, substratebinding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_6738411_0	1131269.AQVV01000006_gene529	2e-101	339.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	oppB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
LZS2_k127_6738411_1	1131269.AQVV01000006_gene528	1.52e-75	263.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02034,ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00566	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.2,3.A.1.5.25	-	iAF1260.b1245,iB21_1397.B21_01229,iEC55989_1330.EC55989_1342,iECBD_1354.ECBD_2377,iECB_1328.ECB_01219,iECDH10B_1368.ECDH10B_1307,iECDH1ME8569_1439.ECDH1ME8569_1185,iECD_1391.ECD_01219,iECIAI1_1343.ECIAI1_1264,iECO103_1326.ECO103_1345,iECO111_1330.ECO111_1572,iECO26_1355.ECO26_1756,iECSE_1348.ECSE_1293,iECSP_1301.ECSP_1637,iECUMN_1333.ECUMN_1542,iECW_1372.ECW_m1337,iECs_1301.ECs1745,iEKO11_1354.EKO11_2607,iETEC_1333.ETEC_1347,iEcDH1_1363.EcDH1_2403,iEcE24377_1341.EcE24377A_1393,iEcHS_1320.EcHS_A1354,iEcolC_1368.EcolC_2383,iG2583_1286.G2583_1517,iJO1366.b1245,iSSON_1240.SSON_1935,iUMNK88_1353.UMNK88_1565,iWFL_1372.ECW_m1337,iY75_1357.Y75_RS06515,iZ_1308.Z2021	BPD_transp_1,OppC_N
LZS2_k127_6738411_3	272134.KB731325_gene547	0.0001427	51.0	COG5278@1|root,COG5278@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA
LZS2_k127_674448_3	452471.Aasi_0897	1.483e-17	85.0	COG3316@1|root,COG3316@2|Bacteria,4NKNK@976|Bacteroidetes,47VVI@768503|Cytophagia	976|Bacteroidetes	L	DDE domain	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
LZS2_k127_674448_2	702113.PP1Y_Mpl11547	5.067e-23	98.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2TUNY@28211|Alphaproteobacteria,2K3US@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS240
LZS2_k127_674448_5	1001240.GY21_20095	1.607e-10	66.0	COG1961@1|root,COG1961@2|Bacteria,2HSUX@201174|Actinobacteria,4FPC3@85023|Microbacteriaceae	201174|Actinobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
LZS2_k127_674448_0	1282362.AEAC466_20500	8.168e-29	123.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2U72X@28211|Alphaproteobacteria,2KH32@204458|Caulobacterales	204458|Caulobacterales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS2_k127_674448_1	553973.CLOHYLEM_06200	8.336e-27	111.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,220VF@1506553|Lachnoclostridium	186801|Clostridia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
LZS2_k127_674448_4	3885.XP_007155092.1	1.525e-11	76.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37ICC@33090|Viridiplantae,3G9ZF@35493|Streptophyta,4JMQP@91835|fabids	35493|Streptophyta	S	F-box LRR-repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,LRR_6,LRR_8
LZS2_k127_6762455_0	469382.Hbor_09140	5.374e-76	263.0	COG0596@1|root,arCOG01648@2157|Archaea,2XSWV@28890|Euryarchaeota,23T2R@183963|Halobacteria	183963|Halobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_6762455_1	644966.Tmar_0739	5.584e-14	83.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UIY4@1239|Firmicutes,25EZX@186801|Clostridia	186801|Clostridia	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
LZS2_k127_6762661_5	859657.RPSI07_1640	0.0003982	46.0	2ECM6@1|root,336J7@2|Bacteria,1N1GI@1224|Proteobacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6762661_3	203124.Tery_4781	1.803e-37	151.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1G2JS@1117|Cyanobacteria,1HAEM@1150|Oscillatoriales	1117|Cyanobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_6762661_4	1170562.Cal6303_1564	7.452e-07	50.0	COG1961@1|root,COG1961@2|Bacteria,1GARG@1117|Cyanobacteria	1117|Cyanobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Resolvase
LZS2_k127_6762661_0	395494.Galf_1465	3.144e-65	229.0	COG4974@1|root,COG4974@2|Bacteria,1R6F9@1224|Proteobacteria,2W3AX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM integrase family protein	-	-	-	ko:K07357,ko:K07358	-	-	-	-	ko00000	-	-	-	Phage_integrase
LZS2_k127_6768201_1	156889.Mmc1_2003	4.368e-51	198.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
LZS2_k127_6768201_0	720554.Clocl_1029	6.281e-53	198.0	COG3021@1|root,COG3021@2|Bacteria,1UKTK@1239|Firmicutes,25G3G@186801|Clostridia,3WNK8@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846,Exo_endo_phos
LZS2_k127_6768201_2	720554.Clocl_1029	2.111e-40	162.0	COG3021@1|root,COG3021@2|Bacteria,1UKTK@1239|Firmicutes,25G3G@186801|Clostridia,3WNK8@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846,Exo_endo_phos
LZS2_k127_6768201_3	386415.NT01CX_0125	1.112e-10	64.0	294DM@1|root,2ZRTK@2|Bacteria,1V8UA@1239|Firmicutes,24IBB@186801|Clostridia,36KD3@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4184)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184
LZS2_k127_6769602_3	309799.DICTH_0934	0.0001117	54.0	COG0745@1|root,COG0745@2|Bacteria	309799.DICTH_0934|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6769602_2	1233950.IW22_04470	2.501e-07	62.0	COG3291@1|root,COG3291@2|Bacteria,4PA0P@976|Bacteroidetes,1ID4A@117743|Flavobacteriia,3ZT38@59732|Chryseobacterium	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6769602_0	1183438.GKIL_3836	1.786e-85	291.0	COG0434@1|root,COG0434@2|Bacteria,1G0P7@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM membrane complex biogenesis protein, BtpA family	btpA	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
LZS2_k127_6769602_1	709986.Deima_0971	9.328e-55	203.0	COG0465@1|root,COG0465@2|Bacteria,1WIXJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_6777208_0	927677.ALVU02000001_gene2158	1.6e-117	403.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria	1117|Cyanobacteria	G	Glycogen debranching enzyme	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	GDE_C,GDE_N
LZS2_k127_6777208_1	1348583.ATLH01000001_gene3730	0.0006882	51.0	COG4339@1|root,COG4339@2|Bacteria,4PKIS@976|Bacteroidetes,1IJAC@117743|Flavobacteriia,1F7YZ@104264|Cellulophaga	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
LZS2_k127_6796152_4	411489.CLOL250_00495	0.0001331	52.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia,36J25@31979|Clostridiaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_6796152_0	1183438.GKIL_2119	7.875e-148	491.0	COG1199@1|root,COG1199@2|Bacteria	2|Bacteria	L	ATP-dependent helicase activity	dinG	GO:0003674,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:1901360	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
LZS2_k127_6796152_3	573370.DMR_33160	1.182e-05	53.0	COG0589@1|root,COG0589@2|Bacteria,1NFYM@1224|Proteobacteria,42VBT@68525|delta/epsilon subdivisions,2WS0B@28221|Deltaproteobacteria,2MDGT@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_6796152_1	304371.MCP_0108	1.037e-88	303.0	COG0306@1|root,arCOG02267@2157|Archaea,2XSUU@28890|Euryarchaeota,2N9TT@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS2_k127_6796152_2	316067.Geob_2115	9.864e-34	143.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2X61A@28221|Deltaproteobacteria,43VZV@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS2_k127_6798150_0	1219084.AP014508_gene886	4.581e-145	479.0	COG1523@1|root,COG1523@2|Bacteria,2GC11@200918|Thermotogae	200918|Thermotogae	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS2_k127_6800239_2	88036.EFJ21357	0.0006993	48.0	COG0457@1|root,KOG1840@2759|Eukaryota,37Q20@33090|Viridiplantae,3GGHD@35493|Streptophyta	35493|Streptophyta	Z	kinesin light chain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_6800239_0	1122927.KB895416_gene3334	6.974e-40	165.0	COG1649@1|root,COG2385@1|root,COG4099@1|root,COG4632@1|root,COG5492@1|root,COG1649@2|Bacteria,COG2385@2|Bacteria,COG4099@2|Bacteria,COG4632@2|Bacteria,COG5492@2|Bacteria,1TRTG@1239|Firmicutes,4HD0M@91061|Bacilli,26QZG@186822|Paenibacillaceae	91061|Bacilli	D	Protein conserved in bacteria	yngK	-	-	-	-	-	-	-	-	-	-	-	Big_2,GHL10,SLH
LZS2_k127_6800239_1	1158338.JNLJ01000001_gene779	2.53e-20	93.0	COG1189@1|root,COG1189@2|Bacteria,2G3MN@200783|Aquificae	200783|Aquificae	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
LZS2_k127_6807785_0	32057.KB217483_gene9297	2.252e-54	209.0	COG2203@1|root,COG3437@1|root,COG4191@1|root,COG5000@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1HMZC@1161|Nostocales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_6812872_2	388467.A19Y_1214	3.832e-26	124.0	COG3014@1|root,COG3014@2|Bacteria,1GR3H@1117|Cyanobacteria,1HI7D@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6812872_1	411471.SUBVAR_04294	7.277e-38	152.0	COG1044@1|root,COG1044@2|Bacteria,1UHYP@1239|Firmicutes,25E78@186801|Clostridia	186801|Clostridia	M	Bacterial transferase hexapeptide	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
LZS2_k127_6812872_0	1183438.GKIL_2326	1.964e-118	394.0	COG0399@1|root,COG0399@2|Bacteria,1G0IM@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_6812872_4	626939.HMPREF9443_00221	8.923e-06	53.0	COG1598@1|root,COG1598@2|Bacteria,1VAII@1239|Firmicutes	1239|Firmicutes	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB,HicB_lk_antitox
LZS2_k127_6812872_3	484770.UFO1_4195	3.903e-26	115.0	COG0859@1|root,COG0859@2|Bacteria,1TRN2@1239|Firmicutes,4H25K@909932|Negativicutes	909932|Negativicutes	M	lipopolysaccharide heptosyltransferase	rfaF	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS2_k127_6816767_1	323848.Nmul_A0331	6.55e-07	53.0	COG0835@1|root,COG0835@2|Bacteria,1RJKY@1224|Proteobacteria,2VTR6@28216|Betaproteobacteria,374AG@32003|Nitrosomonadales	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS2_k127_6816767_0	706587.Desti_0040	7.485e-144	483.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
LZS2_k127_6819842_2	330214.NIDE1562	2.125e-27	115.0	COG0745@1|root,COG0745@2|Bacteria,3J11I@40117|Nitrospirae	40117|Nitrospirae	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_6819842_0	1123508.JH636439_gene1101	1.893e-56	203.0	COG2764@1|root,COG2764@2|Bacteria,2J060@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
LZS2_k127_6819842_3	234267.Acid_3329	4.082e-06	56.0	COG0342@1|root,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS2_k127_6819842_1	525254.HMPREF0072_1808	6.405e-29	125.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,22H3P@1570339|Peptoniphilaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS2_k127_6820837_0	1345023.M467_00100	1.329e-241	764.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,3WEKX@539002|Bacillales incertae sedis	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
LZS2_k127_6820837_2	1382356.JQMP01000004_gene264	1.59e-33	137.0	COG0558@1|root,COG0558@2|Bacteria,2G7HQ@200795|Chloroflexi,27YAM@189775|Thermomicrobia	189775|Thermomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS2_k127_6820837_1	404380.Gbem_0849	3.27e-66	240.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS2_k127_6820837_3	497964.CfE428DRAFT_2911	1.401e-16	87.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
LZS2_k127_6840249_3	1121422.AUMW01000027_gene434	1.985e-26	119.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,26214@186807|Peptococcaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS2_k127_6840249_1	857293.CAAU_2301	1.286e-217	691.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,36DJ7@31979|Clostridiaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS2_k127_6840249_2	1262915.BN574_01773	9.812e-95	325.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H28A@909932|Negativicutes	909932|Negativicutes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS2_k127_6840249_4	78245.Xaut_0027	7.182e-19	100.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TR6Z@28211|Alphaproteobacteria,3EYPM@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Lactonase, 7-bladed beta-propeller	MA20_34510	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
LZS2_k127_6840249_0	398767.Glov_0244	2.421e-320	994.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
LZS2_k127_6846407_0	525257.HMPREF0204_10465	8.199e-09	65.0	COG1538@1|root,COG1538@2|Bacteria,4NIVU@976|Bacteroidetes,1I13I@117743|Flavobacteriia,3ZUAX@59732|Chryseobacterium	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS2_k127_6854210_0	323261.Noc_1703	1.584e-79	286.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,SBP_bac_3,dCache_1
LZS2_k127_6854210_1	1380386.JIAW01000007_gene3820	2.983e-07	61.0	COG0508@1|root,COG0508@2|Bacteria,2GM0D@201174|Actinobacteria,2349S@1762|Mycobacteriaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS2_k127_6863588_1	251221.35212377	9.319e-53	193.0	COG0745@1|root,COG0745@2|Bacteria,1G1DH@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K11521	ko02020,map02020	M00465	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_6863588_0	349521.HCH_03588	8.766e-85	307.0	COG0745@1|root,COG0784@1|root,COG5000@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,CHASE3,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
LZS2_k127_6863588_2	1117108.PAALTS15_06894	4.507e-05	56.0	COG2304@1|root,COG3468@1|root,COG2304@2|Bacteria,COG3468@2|Bacteria,1UJR4@1239|Firmicutes,4ITDS@91061|Bacilli,26UFP@186822|Paenibacillaceae	91061|Bacilli	MU	cell surface receptor IPT TIG domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG,VWA
LZS2_k127_6864718_2	485916.Dtox_0792	2.814e-16	84.0	COG0650@1|root,COG0650@2|Bacteria,1UERZ@1239|Firmicutes,24ARH@186801|Clostridia,260E5@186807|Peptococcaceae	186801|Clostridia	C	Formate hydrogenlyase subunit 4	-	-	-	ko:K12138	-	-	-	-	ko00000,ko01000	-	-	-	NADHdh
LZS2_k127_6864718_1	604331.AUHY01000008_gene445	3.956e-27	119.0	COG4237@1|root,COG4237@2|Bacteria,1WIQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Hydrogenase 4 membrane	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
LZS2_k127_6864718_0	645991.Sgly_0126	1.259e-79	283.0	COG0651@1|root,COG0651@2|Bacteria,1TTBD@1239|Firmicutes,25DGM@186801|Clostridia,26117@186807|Peptococcaceae	186801|Clostridia	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
LZS2_k127_6864718_3	768710.DesyoDRAFT_1181	1.783e-15	81.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1VZGX@1239|Firmicutes,248UJ@186801|Clostridia,25ZYT@186807|Peptococcaceae	186801|Clostridia	C	PFAM Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
LZS2_k127_6901772_0	1128427.KB904821_gene3413	1.757e-295	938.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H8GB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	glsF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
LZS2_k127_691789_1	1174528.JH992898_gene5345	6.826e-13	81.0	COG2091@1|root,COG3321@1|root,COG2091@2|Bacteria,COG3321@2|Bacteria,1G1FH@1117|Cyanobacteria	1117|Cyanobacteria	HQ	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS,Acyl_transf_1,KAsynt_C_assoc,Ketoacyl-synt_C,PS-DH,ketoacyl-synt
LZS2_k127_691789_0	234267.Acid_1972	1.918e-79	283.0	COG1028@1|root,COG2070@1|root,COG3266@1|root,COG3321@1|root,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3266@2|Bacteria,COG3321@2|Bacteria,3Y347@57723|Acidobacteria	57723|Acidobacteria	Q	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
LZS2_k127_6918696_0	1026970.XP_008833499.1	0.0002769	53.0	COG0484@1|root,KOG0550@2759|Eukaryota,38CD1@33154|Opisthokonta,3BAMR@33208|Metazoa,3CY9P@33213|Bilateria,48BGK@7711|Chordata,496I4@7742|Vertebrata,3JBUT@40674|Mammalia,35NQ1@314146|Euarchontoglires,4Q3M6@9989|Rodentia	33208|Metazoa	O	Tetratricopeptide repeat	DNAJC7	GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008047,GO:0008150,GO:0009987,GO:0030234,GO:0031072,GO:0031974,GO:0031981,GO:0032781,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043462,GO:0044093,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0051082,GO:0051084,GO:0051085,GO:0051336,GO:0051345,GO:0060589,GO:0060590,GO:0061077,GO:0065007,GO:0065009,GO:0070013,GO:0080134,GO:0080135,GO:0098772,GO:1900034	-	ko:K09527	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TPR_1,TPR_16,TPR_2,TPR_8
LZS2_k127_6931511_3	1122128.AUEE01000005_gene957	1.49e-21	100.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,4GX1A@90964|Staphylococcaceae	91061|Bacilli	T	Histidine kinase	resE	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
LZS2_k127_6931511_4	376686.Fjoh_0638	2.207e-12	78.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,2NT3G@237|Flavobacterium	976|Bacteroidetes	T	Chemotaxis protein CheY	zraR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_6931511_2	215803.DB30_7269	5.418e-28	118.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,434K9@68525|delta/epsilon subdivisions,2WYXI@28221|Deltaproteobacteria,2Z0V9@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_6931511_1	497964.CfE428DRAFT_4292	2.032e-40	157.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	mauD	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,HEAT_2,Redoxin
LZS2_k127_6931511_0	497964.CfE428DRAFT_4291	5.249e-63	224.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_6938193_0	344747.PM8797T_28259	2.611e-311	990.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,2IWV8@203682|Planctomycetes	203682|Planctomycetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,RNase_H_2
LZS2_k127_6938193_1	1502770.JQMG01000001_gene1017	0.0009931	51.0	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,2VQFW@28216|Betaproteobacteria,2KMV8@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6939530_2	246197.MXAN_4321	3.535e-26	113.0	COG0730@1|root,COG0730@2|Bacteria,1MVBS@1224|Proteobacteria,42THD@68525|delta/epsilon subdivisions,2WQ87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_6939530_0	1283300.ATXB01000001_gene1800	3.676e-130	430.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,1RN27@1236|Gammaproteobacteria,1XDMT@135618|Methylococcales	1236|Gammaproteobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_6939530_1	768671.ThimaDRAFT_4191	6.789e-33	136.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1WWRZ@135613|Chromatiales	135613|Chromatiales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
LZS2_k127_6942294_1	1183438.GKIL_3136	1.025e-70	258.0	COG0617@1|root,COG0617@2|Bacteria,1G1NC@1117|Cyanobacteria	1117|Cyanobacteria	H	tRNA nucleotidyltransferase poly(A) polymerase	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
LZS2_k127_6942294_2	1499967.BAYZ01000090_gene4950	2.051e-28	128.0	COG0392@1|root,COG0392@2|Bacteria,2NPJC@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_6942294_0	1337936.IJ00_21330	3.428e-87	305.0	COG0793@1|root,COG0793@2|Bacteria,1G1YJ@1117|Cyanobacteria,1HKZG@1161|Nostocales	1117|Cyanobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
LZS2_k127_6942294_4	457398.HMPREF0326_03121	4.655e-06	57.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,42SKJ@68525|delta/epsilon subdivisions,2WPDV@28221|Deltaproteobacteria,2MB3U@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
LZS2_k127_6942294_3	887062.HGR_03092	4.122e-10	62.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,4AE0U@80864|Comamonadaceae	28216|Betaproteobacteria	I	Thioesterase superfamily protein	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
LZS2_k127_6951712_0	290512.Paes_0606	1.619e-152	488.0	COG0189@1|root,COG0189@2|Bacteria,1FEIE@1090|Chlorobi	1090|Chlorobi	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
LZS2_k127_6951712_1	644968.DFW101_0703	4.685e-68	248.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2WSVT@28221|Deltaproteobacteria,2MHGC@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS2_k127_6952082_0	1131462.DCF50_p1466	1.999e-67	242.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,260AV@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS2_k127_6952082_2	1337936.IJ00_21310	6.29e-19	93.0	COG4639@1|root,COG4639@2|Bacteria,1G0Y5@1117|Cyanobacteria,1HN7M@1161|Nostocales	1117|Cyanobacteria	S	PFAM Chromatin associated protein KTI12	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
LZS2_k127_6952082_1	879212.DespoDRAFT_00807	1.692e-25	109.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2MKW0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
LZS2_k127_6957816_1	702450.CUW_1112	3.112e-54	215.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,3VP78@526524|Erysipelotrichia	526524|Erysipelotrichia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_6957816_0	635013.TherJR_1773	1.436e-80	278.0	COG0382@1|root,COG0382@2|Bacteria,1TQU5@1239|Firmicutes,2486B@186801|Clostridia,25ZZE@186807|Peptococcaceae	186801|Clostridia	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS2_k127_699876_0	1286093.C266_16295	7.957e-167	535.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2VI4I@28216|Betaproteobacteria,1K4F2@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,MFS_4
LZS2_k127_699876_1	1123508.JH636440_gene2839	5.972e-38	150.0	COG2304@1|root,COG2304@2|Bacteria,2IYXD@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
LZS2_k127_7002103_2	1263831.F543_23500	5.981e-14	78.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1Y8UN@135625|Pasteurellales	135625|Pasteurellales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_7002103_0	1173027.Mic7113_3537	1.502e-82	294.0	COG0212@1|root,COG0212@2|Bacteria,1G2B2@1117|Cyanobacteria,1H86T@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7002103_1	1089553.Tph_c05920	1.754e-70	255.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS2_k127_7004960_2	1217705.F900_00637	2.652e-12	73.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,1SFMR@1236|Gammaproteobacteria,3NNAM@468|Moraxellaceae	1236|Gammaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_7004960_3	1027273.GZ77_02935	4.128e-10	67.0	COG0589@1|root,COG0589@2|Bacteria,1RHE6@1224|Proteobacteria,1S6AR@1236|Gammaproteobacteria,1XK8T@135619|Oceanospirillales	135619|Oceanospirillales	T	Universal stress protein	uspA	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
LZS2_k127_7004960_1	243231.GSU0260	1.269e-15	82.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
LZS2_k127_7004960_0	1183438.GKIL_2945	1.341e-30	126.0	COG2197@1|root,COG2197@2|Bacteria,1FZXR@1117|Cyanobacteria	1117|Cyanobacteria	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_7006284_0	682795.AciX8_1566	1.13e-122	406.0	COG0531@1|root,COG0531@2|Bacteria,3Y3SZ@57723|Acidobacteria,2JI7T@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS2_k127_7006284_1	326423.RBAM_016810	1.404e-33	134.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,1ZC3D@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ymdB	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K02029,ko:K02030,ko:K09769	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	YmdB
LZS2_k127_7007485_1	997350.HMPREF9129_0760	4.917e-11	68.0	COG1957@1|root,COG1957@2|Bacteria,1UY08@1239|Firmicutes,24B2H@186801|Clostridia	186801|Clostridia	F	inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
LZS2_k127_7007485_3	1239962.C943_04469	2.094e-06	58.0	COG4857@1|root,COG4857@2|Bacteria,4NHKI@976|Bacteroidetes,47JME@768503|Cytophagia	976|Bacteroidetes	S	Phosphotransferase enzyme family	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
LZS2_k127_7013854_1	1236959.BAMT01000008_gene2508	6.733e-45	167.0	COG3370@1|root,COG3370@2|Bacteria,1PJNE@1224|Proteobacteria,2W652@28216|Betaproteobacteria,2KNDG@206350|Nitrosomonadales	206350|Nitrosomonadales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
LZS2_k127_7013854_0	402777.KB235898_gene5413	4.085e-79	275.0	COG3576@1|root,COG3576@2|Bacteria,1G2UH@1117|Cyanobacteria,1HAZT@1150|Oscillatoriales	1117|Cyanobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
LZS2_k127_7013854_3	48698.ENSPFOP00000012251	9.308e-09	67.0	KOG1947@1|root,KOG1947@2759|Eukaryota,39R58@33154|Opisthokonta,3BB4U@33208|Metazoa,3D43V@33213|Bilateria,48C0H@7711|Chordata,495N5@7742|Vertebrata,49SRA@7898|Actinopterygii	33208|Metazoa	A	Leucine-rich repeats, outliers	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6,UBX
LZS2_k127_7013854_2	313624.NSP_29050	2.861e-33	143.0	COG2027@1|root,COG2027@2|Bacteria,1G06E@1117|Cyanobacteria,1HJQJ@1161|Nostocales	1117|Cyanobacteria	M	PFAM D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
LZS2_k127_7016681_0	756883.Halar_3102	3.261e-94	323.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea	2157|Archaea	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
LZS2_k127_702776_3	1313421.JHBV01000042_gene3284	6.812e-11	68.0	COG2326@1|root,COG2326@2|Bacteria,4NFJ5@976|Bacteroidetes,1IS28@117747|Sphingobacteriia	976|Bacteroidetes	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
LZS2_k127_702776_2	697282.Mettu_1639	1.995e-25	111.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XG6A@135618|Methylococcales	135618|Methylococcales	C	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Haem_bd
LZS2_k127_702776_1	497964.CfE428DRAFT_6407	1.315e-80	304.0	COG1409@1|root,COG3210@1|root,COG3291@1|root,COG3866@1|root,COG5276@1|root,COG1409@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3866@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	G	Pectate lyase	pnlA	-	4.2.2.10	ko:K01732,ko:K15125,ko:K20276	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000	-	-	-	Big_5,Haemagg_act,HemolysinCabind,LVIVD,Laminin_G_3,PKD,Pec_lyase_C
LZS2_k127_702776_4	573061.Clocel_3193	5.307e-06	61.0	COG1208@1|root,COG2273@1|root,COG1208@2|Bacteria,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.4,3.2.1.78	ko:K01179,ko:K01218	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R01332,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH26,GH5,GH9	-	CBM_4_9,DUF4859,DUF5006,DUF5014,Dockerin_1
LZS2_k127_702776_0	1396141.BATP01000056_gene3277	3.739e-223	729.0	COG3209@1|root,COG3209@2|Bacteria,46TP7@74201|Verrucomicrobia,2IVDA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
LZS2_k127_7035299_0	1541959.KQ51_00282	1.197e-37	144.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppsA	-	2.7.9.2,6.5.1.3	ko:K01007,ko:K14415	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PEP-utilizers,PPDK_N
LZS2_k127_7035299_2	269797.Mbar_A0699	0.000941	51.0	COG5549@1|root,arCOG04994@2157|Archaea,2XZZ9@28890|Euryarchaeota,2NARI@224756|Methanomicrobia	224756|Methanomicrobia	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
LZS2_k127_7035299_1	362242.MUL_0921	4.678e-17	91.0	COG0561@1|root,COG0637@1|root,COG0561@2|Bacteria,COG0637@2|Bacteria,2I50M@201174|Actinobacteria,23F93@1762|Mycobacteriaceae	201174|Actinobacteria	F	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB2	GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0034637,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0071704,GO:0071944,GO:1901576	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
LZS2_k127_7043819_0	768706.Desor_1454	1.859e-96	334.0	COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,25GUN@186801|Clostridia,266BD@186807|Peptococcaceae	186801|Clostridia	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
LZS2_k127_7043819_1	43989.cce_2365	5.784e-29	119.0	COG2197@1|root,COG2197@2|Bacteria,1G1P0@1117|Cyanobacteria,3KFVP@43988|Cyanothece	1117|Cyanobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_7045530_1	1101188.KI912157_gene206	1.379e-37	149.0	COG2801@1|root,COG2801@2|Bacteria,2GP8B@201174|Actinobacteria	201174|Actinobacteria	L	Transposition protein	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,Mu-transpos_C,rve
LZS2_k127_7045530_2	1292020.H483_0117955	6.475e-31	132.0	COG2842@1|root,COG2842@2|Bacteria,2I90A@201174|Actinobacteria	201174|Actinobacteria	S	AAA domain	-	-	3.6.1.3	ko:K07132	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22
LZS2_k127_7045530_3	9371.XP_004699005.1	5.274e-06	58.0	COG0457@1|root,KOG1124@2759|Eukaryota,KOG1126@2759|Eukaryota,38DM6@33154|Opisthokonta,3BEU3@33208|Metazoa,3CW6P@33213|Bilateria,485D1@7711|Chordata,48XAY@7742|Vertebrata,3J72H@40674|Mammalia,3558J@311790|Afrotheria	33208|Metazoa	D	Tetratricopeptide repeat	TTC6	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_7045530_0	545693.BMQ_1799	4.177e-38	149.0	COG4886@1|root,COG4886@2|Bacteria,1VJTM@1239|Firmicutes,4HZD9@91061|Bacilli,1ZHC4@1386|Bacillus	91061|Bacilli	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7050707_1	1122917.KB899667_gene3781	1.614e-40	161.0	COG0028@1|root,COG0028@2|Bacteria,1V0RF@1239|Firmicutes,4HU57@91061|Bacilli,26W67@186822|Paenibacillaceae	91061|Bacilli	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS2_k127_7050707_0	1265490.JHVY01000028_gene2449	3.93e-58	211.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,1SYCI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Guanine deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
LZS2_k127_7050967_0	383372.Rcas_0800	7.053e-72	255.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi,3768U@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
LZS2_k127_7050967_1	43989.cce_4575	6.846e-13	74.0	COG0420@1|root,COG0420@2|Bacteria,1FZXM@1117|Cyanobacteria,3KG3Q@43988|Cyanothece	1117|Cyanobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
LZS2_k127_7052377_0	755178.Cyan10605_2705	5.162e-12	76.0	COG1376@1|root,COG1376@2|Bacteria,1G74K@1117|Cyanobacteria	1117|Cyanobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS2_k127_7060155_0	1449069.JMLO01000031_gene276	1.089e-34	144.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FU85@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_7060155_1	523791.Kkor_2026	8.394e-20	102.0	COG2199@1|root,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,1XHXG@135619|Oceanospirillales	135619|Oceanospirillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
LZS2_k127_7064528_1	332101.JIBU02000084_gene4192	3.87e-42	171.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,36FCZ@31979|Clostridiaceae	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
LZS2_k127_7064528_0	1547445.LO80_06450	5.397e-46	170.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,46077@72273|Thiotrichales	72273|Thiotrichales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS2_k127_7067235_0	1173029.JH980292_gene2948	5.938e-69	249.0	COG1316@1|root,COG1316@2|Bacteria,1G0TR@1117|Cyanobacteria,1H8P2@1150|Oscillatoriales	1117|Cyanobacteria	K	Cell envelope-related transcriptional attenuator	lytR	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
LZS2_k127_7067235_1	251221.35213683	1.583e-47	184.0	COG0859@1|root,COG0859@2|Bacteria,1G0KB@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
LZS2_k127_7067235_2	262724.TT_P0167	2.721e-43	164.0	COG3437@1|root,COG3437@2|Bacteria,1WM13@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HD
LZS2_k127_7068588_1	1242864.D187_006042	6.009e-54	216.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase,TonB_C
LZS2_k127_7068588_0	643648.Slip_0943	7.058e-74	262.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,42JU0@68298|Syntrophomonadaceae	186801|Clostridia	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
LZS2_k127_7068588_2	367336.OM2255_05935	3.093e-05	54.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Methyltransf_23,TPR_1,TPR_10,TPR_11,TPR_12,TPR_16,TPR_2,TPR_8
LZS2_k127_7069265_1	329726.AM1_4383	5.803e-58	216.0	COG0823@1|root,COG0823@2|Bacteria,1G28F@1117|Cyanobacteria	1117|Cyanobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7069265_0	331678.Cphamn1_0666	1.684e-77	263.0	COG0189@1|root,COG0189@2|Bacteria,1FEIE@1090|Chlorobi	1090|Chlorobi	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
LZS2_k127_7084557_0	1140.Synpcc7942_2036	2.428e-24	114.0	COG4638@1|root,COG4638@2|Bacteria,1G45U@1117|Cyanobacteria,1H40C@1129|Synechococcus	1117|Cyanobacteria	P	Rieske [2Fe-2S] domain	hcaE	-	-	-	-	-	-	-	-	-	-	-	Rieske
LZS2_k127_7084557_1	1366050.N234_29125	1.8e-20	102.0	COG4638@1|root,COG4638@2|Bacteria,1MV2G@1224|Proteobacteria,2VI96@28216|Betaproteobacteria,1K4UN@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Rieske 2Fe-2S	-	-	1.14.12.7	ko:K18068	ko00624,ko01100,ko01120,ko01220,map00624,map01100,map01120,map01220	M00623	R03630	RC00951	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
LZS2_k127_7084557_2	666681.M301_2661	1.723e-06	55.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,2KMMY@206350|Nitrosomonadales	206350|Nitrosomonadales	S	UPF0114 protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
LZS2_k127_7094763_0	706587.Desti_1948	5.814e-111	376.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X756@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
LZS2_k127_7098458_0	767817.Desgi_0122	1.003e-119	400.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,2609P@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
LZS2_k127_7099733_3	760568.Desku_3490	1.455e-06	56.0	COG0457@1|root,COG0457@2|Bacteria,1VGEA@1239|Firmicutes	1239|Firmicutes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sel1,TPR_1,TPR_2,TPR_8
LZS2_k127_7099733_1	1128427.KB904821_gene4050	2.399e-73	266.0	COG0457@1|root,COG3063@1|root,COG4995@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_7099733_0	1094980.Mpsy_0846	4.715e-106	350.0	COG0708@1|root,arCOG02207@2157|Archaea,2XVJ5@28890|Euryarchaeota,2N97G@224756|Methanomicrobia	224756|Methanomicrobia	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
LZS2_k127_7099733_2	751945.Theos_2115	1.523e-38	145.0	COG0686@1|root,COG0686@2|Bacteria,1WIQ6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
LZS2_k127_7101045_1	1173028.ANKO01000112_gene4787	1.822e-56	206.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1GBMT@1117|Cyanobacteria,1HE9H@1150|Oscillatoriales	1117|Cyanobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
LZS2_k127_7101045_0	1042163.BRLA_c023900	2.04e-97	331.0	COG5379@1|root,COG5379@2|Bacteria,1V1UP@1239|Firmicutes,4HX2Z@91061|Bacilli	91061|Bacilli	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
LZS2_k127_7101045_2	709986.Deima_1164	9.878e-44	176.0	COG0170@1|root,COG0170@2|Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	-	-	2.7.1.182,2.7.7.41	ko:K00981,ko:K18678	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799,R10659	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1,DUF92
LZS2_k127_7101045_3	89187.ISM_03025	0.0001355	51.0	COG3153@1|root,COG3153@2|Bacteria,1Q6V0@1224|Proteobacteria,2USBK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7106959_3	1380370.JIBA01000019_gene989	1.558e-21	107.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4FEGW@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the peptidase M48B family	htpX	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
LZS2_k127_7106959_2	1365176.N186_04715	6.79e-25	108.0	COG1990@1|root,arCOG04228@2157|Archaea,2XQUQ@28889|Crenarchaeota	28889|Crenarchaeota	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
LZS2_k127_7106959_0	429009.Adeg_2059	3.121e-118	407.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,42EN9@68295|Thermoanaerobacterales	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_7106959_1	552811.Dehly_0476	5.141e-35	146.0	COG0428@1|root,COG0428@2|Bacteria,2G671@200795|Chloroflexi	200795|Chloroflexi	P	ZIP Zinc transporter	-	-	-	ko:K07238,ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11,2.A.5.5	-	-	Zip
LZS2_k127_7106959_5	1254432.SCE1572_02215	3.744e-06	58.0	COG2896@1|root,COG2896@2|Bacteria,1R0BD@1224|Proteobacteria,43CTM@68525|delta/epsilon subdivisions,2X814@28221|Deltaproteobacteria,2Z226@29|Myxococcales	28221|Deltaproteobacteria	H	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_710743_1	1071073.KI530537_gene1729	4.55e-42	167.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,1ZANW@1386|Bacillus	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
LZS2_k127_710743_3	251221.35211704	1.968e-14	78.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS2_k127_710743_0	1183438.GKIL_3744	1.565e-56	204.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS2_k127_710743_2	251221.35213978	4.809e-24	117.0	COG0810@1|root,COG1714@1|root,COG0810@2|Bacteria,COG1714@2|Bacteria,1GQMS@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM TonB family C-terminal domain	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	RDD,TonB_2
LZS2_k127_710743_4	1346.DQ08_03540	0.0002709	53.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli	91061|Bacilli	P	ABC transporter (Permease	malC	GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0042623,GO:0042626,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
LZS2_k127_7116270_1	1049564.TevJSym_bm00200	0.0005849	51.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,1SHID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7121041_0	378806.STAUR_3161	2.562e-203	649.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
LZS2_k127_7131275_1	448385.sce5966	7.533e-51	184.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS2_k127_7131275_0	118163.Ple7327_0472	5.014e-65	248.0	29N3X@1|root,3091P@2|Bacteria,1G154@1117|Cyanobacteria,3VM7V@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7131275_2	999411.HMPREF1092_02623	1.708e-12	70.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,36DD3@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
LZS2_k127_7134230_6	333138.LQ50_17450	9.652e-06	51.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,4H9PF@91061|Bacilli,1ZC6W@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0271 (lamB) family	ycsF	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
LZS2_k127_7134230_5	706191.PANA_2352	6.928e-06	55.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,1RMZS@1236|Gammaproteobacteria,3VYXD@53335|Pantoea	1236|Gammaproteobacteria	NU	Rhs Element Vgr Protein	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Gp5_C,Phage_GPD
LZS2_k127_7134230_4	1120950.KB892707_gene4725	2.784e-09	70.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_7134230_1	118168.MC7420_1870	3.66e-93	325.0	COG1721@1|root,COG1721@2|Bacteria,1G1DK@1117|Cyanobacteria,1H95V@1150|Oscillatoriales	1117|Cyanobacteria	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS2_k127_7134230_0	582515.KR51_00004360	5.557e-113	373.0	COG0714@1|root,COG0714@2|Bacteria,1G1UF@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	morR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_7134230_3	555088.DealDRAFT_1265	9.815e-13	80.0	2A5Z5@1|root,30URA@2|Bacteria,1V56B@1239|Firmicutes,24IP8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7134230_8	1306174.JODP01000001_gene4626	0.0001866	53.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
LZS2_k127_7134230_2	944479.JQLX01000013_gene1442	5.839e-32	145.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,HD_5
LZS2_k127_7139669_2	866536.Belba_0492	6.946e-05	49.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,47M22@768503|Cytophagia	976|Bacteroidetes	L	PFAM Eco57I restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,TaqI_C
LZS2_k127_7139669_3	1160137.KB907310_gene4763	0.0006703	52.0	COG1674@1|root,COG4249@1|root,COG1674@2|Bacteria,COG4249@2|Bacteria,2IBVQ@201174|Actinobacteria,4FXB8@85025|Nocardiaceae	201174|Actinobacteria	D	Caspase domain	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE,Peptidase_C14
LZS2_k127_7139669_1	251221.35213978	1.165e-07	64.0	COG0810@1|root,COG1714@1|root,COG0810@2|Bacteria,COG1714@2|Bacteria,1GQMS@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM TonB family C-terminal domain	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	RDD,TonB_2
LZS2_k127_7139669_0	1304874.JAFY01000007_gene2030	8.436e-15	77.0	COG0268@1|root,COG0268@2|Bacteria,3TBBF@508458|Synergistetes	508458|Synergistetes	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
LZS2_k127_7141716_0	565033.GACE_1956	4.363e-83	293.0	COG2509@1|root,arCOG02231@2157|Archaea,2XTVH@28890|Euryarchaeota,245SB@183980|Archaeoglobi	183980|Archaeoglobi	S	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Pyr_redox_2
LZS2_k127_7141716_1	221288.JH992901_gene3319	1.465e-75	270.0	COG0457@1|root,COG0457@2|Bacteria,1G1QI@1117|Cyanobacteria,1JKFN@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_7141716_3	1499967.BAYZ01000007_gene5399	1.211e-33	141.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
LZS2_k127_7141716_2	880073.Calab_1597	2.912e-52	189.0	COG2107@1|root,COG2107@2|Bacteria,2NQC0@2323|unclassified Bacteria	2|Bacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K07083,ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
LZS2_k127_7141837_1	1348338.ADILRU_2279	7.29e-24	117.0	COG5330@1|root,COG5330@2|Bacteria	2|Bacteria	K	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF2336,LRV,PSCyt2,PSD1,SHD1
LZS2_k127_7141837_0	331869.BAL199_21719	5.284e-52	190.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,4BQQU@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	ahpD	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS2_k127_7141837_2	203124.Tery_2349	7.056e-22	108.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
LZS2_k127_714964_3	1173263.Syn7502_02156	8.445e-15	81.0	COG5401@1|root,COG5401@2|Bacteria,1G6M2@1117|Cyanobacteria,1H0WI@1129|Synechococcus	1117|Cyanobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
LZS2_k127_714964_2	589865.DaAHT2_0607	1.056e-24	106.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,2MM5X@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
LZS2_k127_714964_0	635013.TherJR_1827	1.431e-66	235.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,261JP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
LZS2_k127_714964_1	1209989.TepiRe1_0359	1.002e-44	172.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,42FDQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
LZS2_k127_7151904_0	1218173.BALCAV_0200475	4.257e-61	219.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,1ZBXZ@1386|Bacillus	91061|Bacilli	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
LZS2_k127_7151904_1	1173027.Mic7113_0692	5.634e-60	226.0	COG0457@1|root,COG1994@1|root,COG0457@2|Bacteria,COG1994@2|Bacteria,1G1EH@1117|Cyanobacteria,1HAWT@1150|Oscillatoriales	1117|Cyanobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
LZS2_k127_7151904_3	671143.DAMO_1434	3.578e-06	49.0	COG0236@1|root,COG0236@2|Bacteria,2NPVJ@2323|unclassified Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS2_k127_7151904_2	592029.DDD_2181	7.444e-12	70.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1HY6N@117743|Flavobacteriia,3HKYG@363408|Nonlabens	976|Bacteroidetes	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
LZS2_k127_7168681_0	425104.Ssed_2383	4.132e-14	85.0	COG2246@1|root,COG2246@2|Bacteria,1QUSS@1224|Proteobacteria,1SBSJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7168681_1	314230.DSM3645_16165	2.607e-10	72.0	2DNKJ@1|root,32XZB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7168681_2	204669.Acid345_2555	0.000439	51.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_2555|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7169292_1	756272.Plabr_0903	1.129e-05	57.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Lipase_GDSL_2
LZS2_k127_7169292_0	34740.HMEL005864-PA	2.342e-06	61.0	COG1028@1|root,KOG1565@1|root,KOG1565@2759|Eukaryota,KOG1611@2759|Eukaryota,38CRR@33154|Opisthokonta,3B9IY@33208|Metazoa,3CT1E@33213|Bilateria,41VHF@6656|Arthropoda,3SINR@50557|Insecta,442FM@7088|Lepidoptera	33208|Metazoa	OW	Matrixin	MMP15	GO:0000003,GO:0000139,GO:0001501,GO:0001503,GO:0001525,GO:0001541,GO:0001558,GO:0001568,GO:0001655,GO:0001666,GO:0001704,GO:0001706,GO:0001763,GO:0001775,GO:0001822,GO:0001935,GO:0001944,GO:0001952,GO:0001953,GO:0001958,GO:0002009,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002694,GO:0002696,GO:0003006,GO:0003008,GO:0003674,GO:0003824,GO:0004175,GO:0004177,GO:0004222,GO:0004252,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0005794,GO:0005796,GO:0005802,GO:0005829,GO:0005856,GO:0005886,GO:0005887,GO:0006464,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006979,GO:0007155,GO:0007162,GO:0007275,GO:0007369,GO:0007399,GO:0007492,GO:0007548,GO:0007600,GO:0007610,GO:0007631,GO:0008047,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008236,GO:0008237,GO:0008238,GO:0008270,GO:0008283,GO:0008347,GO:0008406,GO:0008584,GO:0008585,GO:0008593,GO:0009056,GO:0009266,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010001,GO:0010033,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0010810,GO:0010812,GO:0010830,GO:0010831,GO:0010952,GO:0010954,GO:0012505,GO:0012506,GO:0014070,GO:0016020,GO:0016021,GO:0016043,GO:0016048,GO:0016192,GO:0016477,GO:0016485,GO:0016504,GO:0016787,GO:0017171,GO:0019222,GO:0019233,GO:0019538,GO:0019827,GO:0022008,GO:0022411,GO:0022414,GO:0022610,GO:0022617,GO:0023051,GO:0023057,GO:0030141,GO:0030154,GO:0030155,GO:0030162,GO:0030198,GO:0030234,GO:0030307,GO:0030323,GO:0030324,GO:0030334,GO:0030335,GO:0030574,GO:0030659,GO:0030667,GO:0031012,GO:0031090,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031410,GO:0031638,GO:0031974,GO:0031982,GO:0031984,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032588,GO:0032879,GO:0032940,GO:0032963,GO:0035239,GO:0035295,GO:0035579,GO:0035987,GO:0035988,GO:0036075,GO:0036211,GO:0036230,GO:0036293,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0042063,GO:0042119,GO:0042221,GO:0042470,GO:0042581,GO:0042756,GO:0043009,GO:0043062,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043412,GO:0043615,GO:0043627,GO:0044087,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044331,GO:0044352,GO:0044354,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045111,GO:0045137,GO:0045296,GO:0045321,GO:0045577,GO:0045579,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045746,GO:0045862,GO:0045927,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0046872,GO:0046903,GO:0046914,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048568,GO:0048583,GO:0048585,GO:0048598,GO:0048608,GO:0048646,GO:0048701,GO:0048704,GO:0048705,GO:0048706,GO:0048729,GO:0048731,GO:0048754,GO:0048770,GO:0048771,GO:0048856,GO:0048869,GO:0048870,GO:0050673,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050839,GO:0050864,GO:0050865,GO:0050867,GO:0050871,GO:0050877,GO:0050896,GO:0050906,GO:0050951,GO:0050961,GO:0050965,GO:0051094,GO:0051128,GO:0051129,GO:0051147,GO:0051149,GO:0051153,GO:0051155,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051270,GO:0051272,GO:0051336,GO:0051345,GO:0051604,GO:0051606,GO:0051674,GO:0051893,GO:0051895,GO:0052547,GO:0060021,GO:0060022,GO:0060255,GO:0060322,GO:0060348,GO:0060349,GO:0060350,GO:0060429,GO:0060541,GO:0060562,GO:0061134,GO:0061138,GO:0061458,GO:0062009,GO:0065007,GO:0065009,GO:0070006,GO:0070011,GO:0070013,GO:0070482,GO:0070613,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072358,GO:0072359,GO:0080090,GO:0090109,GO:0097094,GO:0097150,GO:0097708,GO:0098588,GO:0098609,GO:0098727,GO:0098742,GO:0098772,GO:0098791,GO:0098805,GO:0099503,GO:0140096,GO:1901564,GO:1901888,GO:1901889,GO:1902105,GO:1902107,GO:1903317,GO:1903319,GO:1903391,GO:1903392,GO:1903706,GO:1903708,GO:1904888,GO:1905521,GO:1905523,GO:1990834,GO:2000026,GO:2000145,GO:2000147	3.4.24.80	ko:K07763,ko:K07995,ko:K07996,ko:K07997,ko:K08002,ko:K08003	ko04668,ko04912,ko05206,map04668,map04912,map05206	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3377,Hemopexin,PG_binding_1,Peptidase_M10
LZS2_k127_7175742_1	384765.SIAM614_26156	1.941e-11	66.0	COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,2TUR1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
LZS2_k127_7175742_0	765911.Thivi_3683	1.264e-208	676.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RN4X@1236|Gammaproteobacteria,1WWY1@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom
LZS2_k127_7176068_1	406124.ACPC01000039_gene14	1.964e-10	73.0	COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,1ZC4F@1386|Bacillus	91061|Bacilli	O	Peptidase M48	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
LZS2_k127_7176068_2	554065.XP_005851129.1	5.019e-05	55.0	COG0457@1|root,KOG1840@2759|Eukaryota,37Q20@33090|Viridiplantae,34KUN@3041|Chlorophyta	3041|Chlorophyta	Z	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12
LZS2_k127_7176068_0	1174528.JH992898_gene5340	2.01e-31	139.0	COG4188@1|root,COG4188@2|Bacteria,1GD7B@1117|Cyanobacteria	1117|Cyanobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
LZS2_k127_7179690_0	251221.35214735	9.497e-68	245.0	COG0642@1|root,COG2205@2|Bacteria,1G113@1117|Cyanobacteria	1117|Cyanobacteria	T	Signal Transduction Histidine Kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_7179690_4	1218075.BAYA01000020_gene4982	2.88e-10	72.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI0K@28216|Betaproteobacteria,1K24U@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_7179690_2	251221.35214734	1.068e-46	185.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2199@2|Bacteria,1GDZC@1117|Cyanobacteria	1117|Cyanobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS2_k127_7179690_1	32049.SYNPCC7002_A1903	1.209e-50	187.0	COG0241@1|root,COG0241@2|Bacteria,1G1I4@1117|Cyanobacteria,1H0DS@1129|Synechococcus	1117|Cyanobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
LZS2_k127_7179690_3	316274.Haur_4494	2.095e-20	95.0	COG3682@1|root,COG3682@2|Bacteria,2GAQU@200795|Chloroflexi,37733@32061|Chloroflexia	32061|Chloroflexia	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
LZS2_k127_7180553_0	1408324.JNJK01000019_gene2503	3.349e-39	164.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,27IE6@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_7192604_0	1347392.CCEZ01000043_gene518	8.534e-54	211.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,36DBS@31979|Clostridiaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_7197475_0	1519439.JPJG01000056_gene2241	5.656e-08	64.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,2N82R@216572|Oscillospiraceae	186801|Clostridia	O	Clp amino terminal domain, pathogenicity island component	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_719775_0	1487921.DP68_14405	2.124e-09	68.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,36NUA@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_7201248_1	1304284.L21TH_1332	9.528e-33	138.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,36DEW@31979|Clostridiaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
LZS2_k127_7201248_0	1041930.Mtc_1015	1.071e-39	163.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03042@2157|Archaea,2Y7M7@28890|Euryarchaeota,2NBM0@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
LZS2_k127_7201248_2	9365.XP_007516078.1	0.0005093	50.0	COG0670@1|root,KOG2322@2759|Eukaryota,39T95@33154|Opisthokonta,3BHWB@33208|Metazoa,3CTGI@33213|Bilateria,48CRX@7711|Chordata,48X7I@7742|Vertebrata,3J56T@40674|Mammalia	33208|Metazoa	T	Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)	GRINA	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006874,GO:0006875,GO:0008150,GO:0008324,GO:0009966,GO:0009968,GO:0009987,GO:0010646,GO:0010648,GO:0010941,GO:0012505,GO:0015075,GO:0015267,GO:0015318,GO:0019725,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0023051,GO:0023057,GO:0030003,GO:0032469,GO:0034220,GO:0042592,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044325,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0060548,GO:0065007,GO:0065008,GO:0072503,GO:0072507,GO:0080134,GO:0080135,GO:0098655,GO:0098771,GO:1902235,GO:1902236,GO:1902531,GO:1902532,GO:1903573,GO:1905897,GO:2001233,GO:2001234,GO:2001242,GO:2001243	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
LZS2_k127_7203812_0	215803.DB30_6122	2.482e-46	175.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,4389R@68525|delta/epsilon subdivisions,2XA3N@28221|Deltaproteobacteria,2YWAI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
LZS2_k127_7203812_2	215803.DB30_0244	6.221e-18	91.0	COG0823@1|root,COG0823@2|Bacteria,1P6XY@1224|Proteobacteria	1224|Proteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS2_k127_7203812_1	555778.Hneap_1419	5.895e-19	94.0	COG5340@1|root,COG5340@2|Bacteria,1R1GM@1224|Proteobacteria,1S2NC@1236|Gammaproteobacteria,1WZ8H@135613|Chromatiales	135613|Chromatiales	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7203812_4	1267535.KB906767_gene2130	1.163e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,3Y4S2@57723|Acidobacteria	57723|Acidobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_7203812_3	927677.ALVU02000001_gene1603	1.059e-05	53.0	COG2385@1|root,COG2385@2|Bacteria,1G2FP@1117|Cyanobacteria,1H4V4@1142|Synechocystis	1117|Cyanobacteria	D	Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
LZS2_k127_7206428_4	110663.KI911558_gene847	1.884e-32	129.0	COG0378@1|root,COG0378@2|Bacteria,1G09M@1117|Cyanobacteria,1GZ93@1129|Synechococcus	1117|Cyanobacteria	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
LZS2_k127_7206428_0	70601.3257710	2.106e-88	303.0	COG1145@1|root,arCOG05128@2157|Archaea,2Y359@28890|Euryarchaeota,2432K@183968|Thermococci	183968|Thermococci	C	4Fe-4S dicluster domain	hydB	-	1.12.98.4	ko:K17996	ko00920,map00920	-	R10390	-	ko00000,ko00001,ko01000	-	-	-	Fer4_22
LZS2_k127_7206428_2	502558.EGYY_12120	1.776e-67	239.0	COG0543@1|root,COG0543@2|Bacteria,2HXFY@201174|Actinobacteria,4CV8F@84998|Coriobacteriia	84998|Coriobacteriia	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
LZS2_k127_7206428_3	374847.Kcr_0322	7.737e-49	184.0	COG1941@1|root,arCOG02472@2157|Archaea	2157|Archaea	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.12.1.3,1.12.1.5	ko:K17994	ko00920,map00920	-	R10390	-	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
LZS2_k127_7206428_1	70601.3257714	1.439e-68	248.0	COG0374@1|root,arCOG01549@2157|Archaea,2Y2IM@28890|Euryarchaeota,2434B@183968|Thermococci	183968|Thermococci	C	Nickel-dependent hydrogenase	-	-	1.12.1.3,1.12.1.5	ko:K17993	ko00920,map00920	-	R10390	-	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
LZS2_k127_7209922_1	246197.MXAN_7363	1.238e-42	162.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43C8M@68525|delta/epsilon subdivisions,2X7J0@28221|Deltaproteobacteria,2YXZD@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
LZS2_k127_7209922_0	489825.LYNGBM3L_11800	1.064e-59	215.0	COG0745@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,1G027@1117|Cyanobacteria,1H8EH@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg,Trans_reg_C
LZS2_k127_7209922_2	234267.Acid_0775	8.214e-07	53.0	COG2802@1|root,COG2802@2|Bacteria,3Y7UX@57723|Acidobacteria	57723|Acidobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LON_substr_bdg
LZS2_k127_7227593_0	338966.Ppro_2669	1.25e-84	291.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,42SX1@68525|delta/epsilon subdivisions,2X5WJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS2_k127_7228481_0	1536774.H70357_23080	2.852e-20	96.0	COG3420@1|root,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4HCY7@91061|Bacilli,26TS4@186822|Paenibacillaceae	91061|Bacilli	P	Parallel beta-helix repeat-containing protein	ywoF	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
LZS2_k127_7228481_1	109478.XP_005861065.1	2.147e-05	56.0	COG0457@1|root,KOG1840@2759|Eukaryota,38CFM@33154|Opisthokonta,3BC82@33208|Metazoa,3CWNT@33213|Bilateria,483PC@7711|Chordata,48V59@7742|Vertebrata,3JBF8@40674|Mammalia,4KZJZ@9397|Chiroptera	33208|Metazoa	Z	Kinesin light chain 4	KLC4	GO:0000003,GO:0000226,GO:0000280,GO:0000902,GO:0000904,GO:0000910,GO:0002064,GO:0002065,GO:0002066,GO:0002119,GO:0002164,GO:0003006,GO:0003674,GO:0003774,GO:0003777,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005856,GO:0005871,GO:0005875,GO:0006810,GO:0006928,GO:0006996,GO:0007010,GO:0007017,GO:0007018,GO:0007049,GO:0007097,GO:0007143,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007304,GO:0007306,GO:0007399,GO:0007409,GO:0008092,GO:0008150,GO:0009653,GO:0009791,GO:0009888,GO:0009987,GO:0010927,GO:0010970,GO:0012505,GO:0015630,GO:0016043,GO:0016049,GO:0016192,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016938,GO:0017111,GO:0019894,GO:0019953,GO:0022008,GO:0022402,GO:0022412,GO:0022414,GO:0022607,GO:0030030,GO:0030154,GO:0030182,GO:0030473,GO:0030703,GO:0030705,GO:0030707,GO:0030855,GO:0031175,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032504,GO:0032989,GO:0032990,GO:0032991,GO:0033206,GO:0040007,GO:0040011,GO:0040038,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044085,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044446,GO:0044464,GO:0044703,GO:0046843,GO:0046907,GO:0048285,GO:0048468,GO:0048477,GO:0048489,GO:0048588,GO:0048589,GO:0048609,GO:0048646,GO:0048666,GO:0048667,GO:0048675,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0051179,GO:0051234,GO:0051293,GO:0051295,GO:0051301,GO:0051321,GO:0051640,GO:0051641,GO:0051647,GO:0051648,GO:0051649,GO:0051650,GO:0051653,GO:0051656,GO:0051704,GO:0060429,GO:0060560,GO:0061564,GO:0061640,GO:0071840,GO:0072384,GO:0097479,GO:0097480,GO:0099003,GO:0099111,GO:0120036,GO:0120039,GO:0140013,GO:1903046,GO:1990138	-	ko:K10407	ko05132,map05132	-	-	-	ko00000,ko00001,ko03019,ko04812	-	-	-	TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_7228986_0	391615.ABSJ01000037_gene836	3.916e-223	712.0	COG4644@1|root,COG4644@2|Bacteria,1MUIU@1224|Proteobacteria,1RPZZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
LZS2_k127_7228986_1	1442598.JABW01000009_gene177	1.455e-57	203.0	COG1961@1|root,COG1961@2|Bacteria,1MXXT@1224|Proteobacteria	1224|Proteobacteria	L	Site-specific recombinases DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
LZS2_k127_7256867_0	388467.A19Y_4107	6.55e-93	308.0	COG0468@1|root,COG0468@2|Bacteria,1G14C@1117|Cyanobacteria,1H7PM@1150|Oscillatoriales	1117|Cyanobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
LZS2_k127_7256867_1	269799.Gmet_2367	1.11e-39	166.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS2_k127_7262367_1	321332.CYB_1515	1.821e-05	59.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1GZAT@1129|Synechococcus	1117|Cyanobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_7262367_0	632335.Calkr_1515	7.891e-58	230.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,42IJP@68295|Thermoanaerobacterales	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,WG_beta_rep
LZS2_k127_7262367_2	1170562.Cal6303_3142	0.0008789	47.0	COG0457@1|root,COG0457@2|Bacteria,1G0N0@1117|Cyanobacteria,1HQK0@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_726246_0	479433.Caci_0038	1.074e-44	185.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_726246_1	1142394.PSMK_05030	3.287e-36	144.0	COG0388@1|root,COG0388@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
LZS2_k127_7263503_2	926549.KI421517_gene404	3.413e-86	293.0	COG2126@1|root,COG2126@2|Bacteria,4NEX1@976|Bacteroidetes,47NAG@768503|Cytophagia	976|Bacteroidetes	J	PFAM Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
LZS2_k127_7263503_5	1408422.JHYF01000008_gene3798	6.319e-12	74.0	2BW4G@1|root,2ZAQH@2|Bacteria,1UZFJ@1239|Firmicutes,24DAB@186801|Clostridia,36IC8@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7263503_4	748449.Halha_2123	1.248e-61	230.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WBDR@53433|Halanaerobiales	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	norM	-	-	-	-	-	-	-	-	-	-	-	MatE
LZS2_k127_7263503_0	1069080.KB913028_gene833	9.453e-102	342.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4H30W@909932|Negativicutes	909932|Negativicutes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS2_k127_7263503_1	891968.Anamo_0432	3.751e-100	336.0	COG0568@1|root,COG0568@2|Bacteria,3TACS@508458|Synergistetes	508458|Synergistetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_7263503_3	292459.STH539	5.634e-65	234.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS2_k127_7268753_2	251221.35213935	5.874e-117	382.0	COG2086@1|root,COG2086@2|Bacteria,1GBI7@1117|Cyanobacteria	1117|Cyanobacteria	C	Electron transfer flavoprotein, beta subunit FixA family protein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
LZS2_k127_7268753_1	321327.CYA_2735	1.174e-160	514.0	COG2025@1|root,COG2025@2|Bacteria,1GC7B@1117|Cyanobacteria,1H2J1@1129|Synechococcus	1117|Cyanobacteria	C	Electron transfer flavoprotein, alpha subunit FixB family protein	-	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha
LZS2_k127_7268753_0	251221.35213933	1.552e-212	674.0	COG0644@1|root,COG1146@1|root,COG0644@2|Bacteria,COG1146@2|Bacteria,1GCP1@1117|Cyanobacteria	1117|Cyanobacteria	C	oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
LZS2_k127_7268753_4	1132855.KB913035_gene957	9.854e-19	96.0	COG2067@1|root,COG2067@2|Bacteria,1R172@1224|Proteobacteria	1224|Proteobacteria	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
LZS2_k127_7268753_3	485916.Dtox_2580	3.181e-23	104.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,2625T@186807|Peptococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
LZS2_k127_7269509_3	335543.Sfum_4020	1.188e-08	64.0	COG5523@1|root,COG5523@2|Bacteria,1QZ4S@1224|Proteobacteria	1224|Proteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7269509_1	316274.Haur_3686	1.139e-35	151.0	COG1705@1|root,COG1705@2|Bacteria,2G9KG@200795|Chloroflexi,375T2@32061|Chloroflexia	32061|Chloroflexia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
LZS2_k127_7269509_4	1118054.CAGW01000024_gene379	0.0008316	44.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,4HBMK@91061|Bacilli,26U2U@186822|Paenibacillaceae	91061|Bacilli	S	AIR carboxylase	larB	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
LZS2_k127_7269509_0	710111.FraQA3DRAFT_1876	6.103e-130	425.0	COG0371@1|root,COG0371@2|Bacteria,2GKWA@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase	gldA	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
LZS2_k127_7269509_2	945713.IALB_2785	1.884e-33	132.0	COG1393@1|root,COG1393@2|Bacteria	2|Bacteria	P	arsenate reductase (glutaredoxin) activity	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
LZS2_k127_7274520_1	1121403.AUCV01000018_gene3180	2.234e-26	120.0	2DWP7@1|root,3419S@2|Bacteria,1NXHT@1224|Proteobacteria,430NG@68525|delta/epsilon subdivisions,2WVKS@28221|Deltaproteobacteria,2MNQW@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7274520_0	1385512.N784_05875	2.74e-28	121.0	COG0494@1|root,COG0494@2|Bacteria,1UNS3@1239|Firmicutes,4IUNJ@91061|Bacilli	91061|Bacilli	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS2_k127_7274520_2	1408422.JHYF01000009_gene2083	2.187e-06	55.0	COG1131@1|root,COG1131@2|Bacteria,1TRNT@1239|Firmicutes,24B5J@186801|Clostridia,36FNP@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_7275162_0	479435.Kfla_5399	6.193e-15	77.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DQTY@85009|Propionibacteriales	201174|Actinobacteria	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_7276935_1	478741.JAFS01000001_gene1051	6.05e-18	86.0	COG0842@1|root,COG0842@2|Bacteria,46UQ0@74201|Verrucomicrobia,37GJ6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS2_k127_7276935_0	240016.ABIZ01000001_gene5181	4.101e-82	279.0	COG1131@1|root,COG1131@2|Bacteria,46UP6@74201|Verrucomicrobia,2IVD6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS2_k127_7276935_2	1174504.AJTN02000206_gene3473	0.0002968	52.0	COG0477@1|root,COG2814@2|Bacteria,1TQEW@1239|Firmicutes,4HASU@91061|Bacilli,1ZB5B@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	ymfD	-	-	ko:K08221	-	-	-	-	ko00000,ko02000	2.A.1.32	-	-	MFS_1,MFS_2,Sugar_tr
LZS2_k127_7292092_1	63737.Npun_R3473	9.961e-30	128.0	COG1216@1|root,COG1216@2|Bacteria,1G0X3@1117|Cyanobacteria,1HK6N@1161|Nostocales	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064,Glycos_transf_2
LZS2_k127_7292092_0	237368.SCABRO_01822	9.993e-84	293.0	COG1249@1|root,COG1249@2|Bacteria,2IYD2@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS2_k127_7301909_4	1340434.AXVA01000010_gene5259	0.0001228	47.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,1ZAPY@1386|Bacillus	91061|Bacilli	V	COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
LZS2_k127_7301909_5	1123376.AUIU01000014_gene682	0.0001761	52.0	COG2854@1|root,COG2854@2|Bacteria,3J13Z@40117|Nitrospirae	40117|Nitrospirae	Q	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
LZS2_k127_7301909_2	1282876.BAOK01000001_gene1574	2.368e-47	179.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2U10V@28211|Alphaproteobacteria,4BQ4H@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
LZS2_k127_7301909_3	1463856.JOHY01000031_gene2784	5.198e-08	64.0	COG4842@1|root,COG4842@2|Bacteria,2IQDW@201174|Actinobacteria	201174|Actinobacteria	S	Calpain-like thiol protease family.	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C2
LZS2_k127_7301909_1	697281.Mahau_2005	9.116e-57	224.0	COG0286@1|root,COG0286@2|Bacteria,1UMGW@1239|Firmicutes,25GHR@186801|Clostridia	186801|Clostridia	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
LZS2_k127_7301909_0	562970.Btus_2368	1.274e-97	326.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,278TC@186823|Alicyclobacillaceae	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS2_k127_7304185_0	489825.LYNGBM3L_28020	8.497e-65	229.0	COG5316@1|root,COG5316@2|Bacteria,1GD0X@1117|Cyanobacteria,1HESQ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7304185_1	1499684.CCNP01000018_gene1769	1.179e-11	68.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,36VPN@31979|Clostridiaceae	186801|Clostridia	G	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS2_k127_7310346_2	1120973.AQXL01000089_gene3251	1.795e-53	192.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.32,1.2.1.85	ko:K10217	ko00362,ko00380,ko00622,ko01100,ko01120,ko01220,map00362,map00380,map00622,map01100,map01120,map01220	M00038,M00569	R02762,R03889,R05353	RC00218,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_7310346_1	1191523.MROS_1927	4.593e-66	235.0	COG1028@1|root,COG1028@2|Bacteria	1191523.MROS_1927|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
LZS2_k127_7310346_0	1379698.RBG1_1C00001G0675	3.261e-73	261.0	COG1748@1|root,COG1748@2|Bacteria,2NPF8@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
LZS2_k127_7315802_0	351160.RCIX2387	1.274e-97	343.0	COG0651@1|root,arCOG01537@2157|Archaea,2Y85B@28890|Euryarchaeota,2NAGR@224756|Methanomicrobia	224756|Methanomicrobia	C	plastoquinone (Complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
LZS2_k127_7315802_1	326427.Cagg_2325	2.32e-70	252.0	COG1171@1|root,COG1171@2|Bacteria,2G6ME@200795|Chloroflexi,3776A@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_7319131_0	264462.Bd2936	1.881e-27	116.0	COG3011@1|root,COG3011@2|Bacteria,1Q0ET@1224|Proteobacteria,433PE@68525|delta/epsilon subdivisions,2MUHT@213481|Bdellovibrionales,2WXRA@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Vitamin K-dependent gamma-carboxylase	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
LZS2_k127_7319131_1	909663.KI867150_gene2934	0.000715	50.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MR1G@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
LZS2_k127_7320672_3	118173.KB235914_gene1099	0.0001086	45.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1H87F@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS2_k127_7320672_0	1410612.JNKO01000011_gene335	1.051e-27	115.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,2PSM4@265975|Oribacterium	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_7320672_2	1122990.BAJH01000011_gene1564	3.637e-13	79.0	COG0546@1|root,COG0546@2|Bacteria,4PKHW@976|Bacteroidetes,2G09E@200643|Bacteroidia	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_7320672_1	3760.EMJ16724	6.538e-16	79.0	COG0524@1|root,KOG2855@2759|Eukaryota,37HW8@33090|Viridiplantae,3G8M2@35493|Streptophyta,4JKW7@91835|fabids	35493|Streptophyta	G	Belongs to the carbohydrate kinase PfkB family	-	GO:0003674,GO:0003824,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005911,GO:0005975,GO:0005996,GO:0006000,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008865,GO:0009058,GO:0009506,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016051,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0019752,GO:0030054,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044262,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046835,GO:0055044,GO:0071704,GO:0072330,GO:1901576	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS2_k127_7321385_1	1079460.ATTQ01000022_gene774	7.725e-53	199.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2TVZD@28211|Alphaproteobacteria,4BCBC@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Aspartate ammonia-lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS2_k127_7321385_2	309798.COPRO5265_0834	1.344e-42	165.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,42GF5@68295|Thermoanaerobacterales	186801|Clostridia	F	thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
LZS2_k127_7321385_0	1235279.C772_01381	5.031e-122	403.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,26ECQ@186818|Planococcaceae	91061|Bacilli	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_7321385_3	29306.JOBE01000060_gene1036	4.582e-18	85.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
LZS2_k127_73497_2	373994.Riv7116_5725	2.591e-39	153.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS2_k127_73497_4	448385.sce5332	0.0003338	53.0	2DBR9@1|root,2ZAJD@2|Bacteria,1R7F3@1224|Proteobacteria,435AD@68525|delta/epsilon subdivisions,2WZME@28221|Deltaproteobacteria,2Z2DE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_73497_1	118161.KB235922_gene3255	4.666e-65	241.0	COG0661@1|root,COG0661@2|Bacteria,1G0X9@1117|Cyanobacteria,3VI6A@52604|Pleurocapsales	1117|Cyanobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
LZS2_k127_73497_0	1173025.GEI7407_1445	4.985e-70	251.0	COG0500@1|root,COG2226@2|Bacteria,1G36P@1117|Cyanobacteria,1H9UT@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_73497_3	631362.Thi970DRAFT_01828	4.553e-32	135.0	COG0561@1|root,COG0561@2|Bacteria,1N9QG@1224|Proteobacteria,1RMVG@1236|Gammaproteobacteria,1WWS9@135613|Chromatiales	135613|Chromatiales	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7351899_3	1304875.JAFZ01000003_gene618	4.201e-17	83.0	COG0263@1|root,COG0263@2|Bacteria,3TAMZ@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
LZS2_k127_7351899_1	903818.KI912268_gene930	1.737e-57	211.0	COG0263@1|root,COG0263@2|Bacteria,3Y51F@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
LZS2_k127_7351899_2	234267.Acid_6517	4.231e-50	188.0	COG0124@1|root,COG0124@2|Bacteria,3Y4H5@57723|Acidobacteria	57723|Acidobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7351899_0	266265.Bxe_A0918	9.515e-137	444.0	COG0178@1|root,COG0178@2|Bacteria,1MX79@1224|Proteobacteria,2VMTX@28216|Betaproteobacteria,1K39K@119060|Burkholderiaceae	28216|Betaproteobacteria	L	TIGRFAM excinuclease ABC, A subunit	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS2_k127_735656_1	697303.Thewi_0616	9.139e-93	312.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	bcd	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108,1.3.8.1	ko:K00248,ko:K22430	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_735656_0	1123511.KB905854_gene3641	5.752e-126	413.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4H2UD@909932|Negativicutes	909932|Negativicutes	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	mnaA	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS2_k127_735656_2	313603.FB2170_15578	1.079e-44	174.0	COG3509@1|root,COG3509@2|Bacteria,4NHFS@976|Bacteroidetes,1I3VW@117743|Flavobacteriia,2PIT7@252356|Maribacter	976|Bacteroidetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
LZS2_k127_735656_3	1123284.KB899050_gene1812	1.875e-12	70.0	COG0670@1|root,COG0670@2|Bacteria,1V779@1239|Firmicutes,4HIX1@91061|Bacilli,26PKJ@186821|Sporolactobacillaceae	91061|Bacilli	S	Inhibitor of apoptosis-promoting Bax1	ybhL	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
LZS2_k127_7361251_4	338966.Ppro_2898	1.693e-07	59.0	COG1708@1|root,COG1708@2|Bacteria,1NKZT@1224|Proteobacteria,430VC@68525|delta/epsilon subdivisions,2WVUS@28221|Deltaproteobacteria,43VAP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
LZS2_k127_7361251_2	46234.ANA_C12350	4.978e-25	122.0	COG0457@1|root,COG0457@2|Bacteria,1G0N0@1117|Cyanobacteria,1HQK0@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_7361251_1	1173029.JH980292_gene2933	4.242e-70	249.0	COG1621@1|root,COG1621@2|Bacteria,1G4BM@1117|Cyanobacteria,1HD4H@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolases family 32 N-terminal domain	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N
LZS2_k127_7361251_0	421072.IO89_14380	7.696e-119	396.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1HY5U@117743|Flavobacteriia,3HHNN@358033|Chryseobacterium	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_7361251_3	1071073.KI530537_gene2189	1.477e-24	107.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HD08@91061|Bacilli,1ZPZV@1386|Bacillus	91061|Bacilli	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_7364356_0	468059.AUHA01000003_gene1915	7.565e-155	500.0	COG1972@1|root,COG1972@2|Bacteria,4NEYN@976|Bacteroidetes,1IRNQ@117747|Sphingobacteriia	976|Bacteroidetes	F	Na dependent nucleoside transporter	nupC	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
LZS2_k127_7364356_1	1382358.JHVN01000015_gene645	8.004e-86	290.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,21V1R@150247|Anoxybacillus	91061|Bacilli	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
LZS2_k127_7378244_2	111780.Sta7437_2550	5.386e-08	58.0	COG0457@1|root,COG0457@2|Bacteria	111780.Sta7437_2550|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7378244_1	316055.RPE_4585	1.18e-54	205.0	COG2374@1|root,COG2374@2|Bacteria,1RA34@1224|Proteobacteria,2U9B5@28211|Alphaproteobacteria,3JZXP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616
LZS2_k127_7378244_0	452471.Aasi_0854	6.322e-59	217.0	COG0790@1|root,COG0790@2|Bacteria,4NMCC@976|Bacteroidetes,47QS2@768503|Cytophagia	976|Bacteroidetes	KLT	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Pkinase,Sel1,Tox-ODYAM1,U-box
LZS2_k127_7381182_0	1174528.JH992893_gene5975	3.109e-162	524.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1G15G@1117|Cyanobacteria,1JHXK@1189|Stigonemataceae	1117|Cyanobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
LZS2_k127_7393799_0	290512.Paes_0606	7.125e-139	449.0	COG0189@1|root,COG0189@2|Bacteria,1FEIE@1090|Chlorobi	1090|Chlorobi	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
LZS2_k127_7393799_2	502025.Hoch_5204	9.957e-88	296.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,42MXW@68525|delta/epsilon subdivisions,2WK94@28221|Deltaproteobacteria,2YWE8@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
LZS2_k127_7393799_1	555088.DealDRAFT_2951	2.981e-124	417.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,248A1@186801|Clostridia,42KFA@68298|Syntrophomonadaceae	186801|Clostridia	P	Substrate-binding region of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
LZS2_k127_7393799_3	1380394.JADL01000004_gene6036	5.26e-69	246.0	COG3239@1|root,COG3239@2|Bacteria,1MXA8@1224|Proteobacteria,2TUQG@28211|Alphaproteobacteria,2JSA5@204441|Rhodospirillales	204441|Rhodospirillales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
LZS2_k127_7393799_4	536232.CLM_2978	1.724e-18	93.0	COG2897@1|root,COG2897@2|Bacteria,1TRYA@1239|Firmicutes,24AGI@186801|Clostridia,36EXT@31979|Clostridiaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
LZS2_k127_7396480_1	113355.CM001775_gene3111	2.87e-13	75.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
LZS2_k127_7396480_2	1183438.GKIL_0177	1.211e-12	80.0	COG0265@1|root,COG0457@1|root,COG5549@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,COG5549@2|Bacteria,1G8MC@1117|Cyanobacteria	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M10,TPR_1,TPR_11,TPR_16,TPR_8
LZS2_k127_7396480_0	552811.Dehly_0476	7.766e-32	136.0	COG0428@1|root,COG0428@2|Bacteria,2G671@200795|Chloroflexi	200795|Chloroflexi	P	ZIP Zinc transporter	-	-	-	ko:K07238,ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11,2.A.5.5	-	-	Zip
LZS2_k127_7402252_0	56110.Oscil6304_2639	2.511e-84	295.0	COG0772@1|root,COG0772@2|Bacteria,1G0F0@1117|Cyanobacteria,1H75Q@1150|Oscillatoriales	1117|Cyanobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
LZS2_k127_7402252_1	1173028.ANKO01000112_gene4788	1.721e-64	233.0	COG0382@1|root,COG0382@2|Bacteria,1GBH5@1117|Cyanobacteria,1HE6Y@1150|Oscillatoriales	1117|Cyanobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS2_k127_7402252_2	1321779.HMPREF1984_00496	1.926e-54	205.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,379XF@32066|Fusobacteria	32066|Fusobacteria	GT	pyruvate, water dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
LZS2_k127_7407459_0	1340493.JNIF01000004_gene336	4.107e-77	265.0	COG0010@1|root,COG0010@2|Bacteria,3Y5KF@57723|Acidobacteria	57723|Acidobacteria	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
LZS2_k127_7407459_1	1384049.CD29_05945	3.027e-44	170.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,4HBHA@91061|Bacilli,3IX41@400634|Lysinibacillus	91061|Bacilli	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
LZS2_k127_7407459_2	632292.Calhy_0924	4.579e-38	159.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,42F75@68295|Thermoanaerobacterales	186801|Clostridia	K	Fibronectin-binding A domain protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
LZS2_k127_741558_0	768706.Desor_4444	5.335e-09	63.0	COG1357@1|root,COG1357@2|Bacteria,1VAPB@1239|Firmicutes,24J9N@186801|Clostridia	186801|Clostridia	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
LZS2_k127_7430226_0	335543.Sfum_2378	1.481e-153	497.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,42MST@68525|delta/epsilon subdivisions,2WKAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
LZS2_k127_7430226_1	1009370.ALO_13804	3.955e-138	451.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H2ZB@909932|Negativicutes	909932|Negativicutes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.82	ko:K09251	ko00330,ko01100,map00330,map01100	-	R01155	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_7430226_2	1041930.Mtc_1015	1.814e-67	251.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03042@2157|Archaea,2Y7M7@28890|Euryarchaeota,2NBM0@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
LZS2_k127_7433196_1	5888.CAK76643	1.527e-07	60.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZD5C@5878|Ciliophora	5878|Ciliophora	GOT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
LZS2_k127_7433196_0	98439.AJLL01000022_gene933	8.776e-22	103.0	COG2202@1|root,COG2203@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1JJNN@1189|Stigonemataceae	1117|Cyanobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_7433632_2	330214.NIDE3119	1.058e-68	243.0	COG0491@1|root,COG0491@2|Bacteria,3J1C9@40117|Nitrospirae	40117|Nitrospirae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_7433632_1	203119.Cthe_0572	1.651e-89	307.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3WGYF@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
LZS2_k127_7433632_0	401053.AciPR4_2562	6.03e-142	462.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
LZS2_k127_7442392_0	1382359.JIAL01000001_gene2059	3.716e-139	451.0	COG1060@1|root,COG1060@2|Bacteria,3Y677@57723|Acidobacteria,2JKTA@204432|Acidobacteriia	204432|Acidobacteriia	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_7442392_1	497964.CfE428DRAFT_5475	6.426e-75	261.0	COG4320@1|root,COG4320@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
LZS2_k127_7461660_0	1191523.MROS_0095	1.616e-53	196.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	fucA	-	2.7.1.189,4.1.2.17,5.1.3.4	ko:K01628,ko:K03077,ko:K11216	ko00040,ko00051,ko00053,ko01100,ko01120,ko02024,map00040,map00051,map00053,map01100,map01120,map02024	M00550	R02262,R05850,R11183	RC00002,RC00017,RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
LZS2_k127_7461660_1	656519.Halsa_2208	1.063e-27	120.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia,3WBYJ@53433|Halanaerobiales	186801|Clostridia	G	PFAM Phosphoglycerate mutase	pspA	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
LZS2_k127_7467021_3	502025.Hoch_3397	2.896e-12	75.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7467021_2	1123376.AUIU01000017_gene102	4.478e-24	102.0	COG3585@1|root,COG3585@2|Bacteria	2|Bacteria	H	molybdate ion transport	modE	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,TOBE
LZS2_k127_7467021_0	706587.Desti_1056	2.923e-183	584.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Pyridoxal-dependent decarboxylase	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	EF-hand_7,Pyridoxal_deC
LZS2_k127_7467021_1	1382356.JQMP01000004_gene488	2.901e-99	329.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
LZS2_k127_7472915_0	118166.JH976538_gene5020	1.078e-50	190.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7R4@1150|Oscillatoriales	1117|Cyanobacteria	K	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,Pentapeptide,WD40
LZS2_k127_7472915_1	388467.A19Y_2309	5.106e-30	138.0	COG4249@1|root,COG4249@2|Bacteria,1G9TD@1117|Cyanobacteria	1117|Cyanobacteria	KLT	protein containing caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
LZS2_k127_7472915_2	545694.TREPR_3648	2.214e-12	81.0	COG0457@1|root,COG0457@2|Bacteria,2J8HR@203691|Spirochaetes	203691|Spirochaetes	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_7489289_0	525909.Afer_0087	4.553e-43	180.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CMUZ@84992|Acidimicrobiia	84992|Acidimicrobiia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_7497409_1	136993.KB900626_gene3822	5.42e-17	89.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_7497409_0	1211817.CCAT010000065_gene624	4.143e-17	90.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,36JKN@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
LZS2_k127_7507026_2	502025.Hoch_5412	2.966e-82	278.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,42PY3@68525|delta/epsilon subdivisions,2X2PN@28221|Deltaproteobacteria,2YXEC@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
LZS2_k127_7507026_0	1341151.ASZU01000006_gene2846	2.588e-222	700.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,27BDW@186824|Thermoactinomycetaceae	91061|Bacilli	C	Aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
LZS2_k127_7507026_3	1229172.JQFA01000002_gene4197	3.823e-17	86.0	2DI16@1|root,301P4@2|Bacteria,1G5UH@1117|Cyanobacteria,1HB0C@1150|Oscillatoriales	1117|Cyanobacteria	S	YlqD protein	-	-	-	-	-	-	-	-	-	-	-	-	YlqD
LZS2_k127_7507026_1	476272.RUMHYD_03093	3.124e-95	322.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3XZ4I@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_7512324_0	1282876.BAOK01000002_gene521	2.113e-119	392.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	NADP-dependent oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
LZS2_k127_7512324_1	1472716.KBK24_0101205	1.221e-32	127.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2VNDX@28216|Betaproteobacteria,1K0TY@119060|Burkholderiaceae	28216|Betaproteobacteria	V	beta-lactamase	ampC	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
LZS2_k127_7515554_0	387092.NIS_0310	1.64e-114	387.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2YNAQ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
LZS2_k127_7515554_1	1173023.KE650771_gene2207	1.718e-95	323.0	COG4294@1|root,COG4294@2|Bacteria,1G10X@1117|Cyanobacteria,1JH3R@1189|Stigonemataceae	1117|Cyanobacteria	L	UV-endonuclease UvdE	uvsE	-	-	ko:K13281	-	-	-	-	ko00000,ko01000	-	-	-	UvdE
LZS2_k127_7516781_2	251221.35212581	1.57e-08	58.0	COG1566@1|root,COG1566@2|Bacteria,1G0GH@1117|Cyanobacteria	1117|Cyanobacteria	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS2_k127_7516781_1	1347086.CCBA010000027_gene3304	2.504e-10	69.0	COG1309@1|root,COG1309@2|Bacteria,1TPXF@1239|Firmicutes,4HCMD@91061|Bacilli,1ZDYI@1386|Bacillus	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS2_k127_7516781_0	1157490.EL26_00625	4.827e-175	568.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,2781B@186823|Alicyclobacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_7528508_1	1121090.KB894690_gene531	1.141e-76	266.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HAM3@91061|Bacilli,1ZD31@1386|Bacillus	91061|Bacilli	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS2_k127_7528508_0	240016.ABIZ01000001_gene5681	1.827e-112	376.0	COG4102@1|root,COG4102@2|Bacteria,46T50@74201|Verrucomicrobia,2IUKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS2_k127_7528508_2	1396418.BATQ01000184_gene2578	3.992e-13	72.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia,2IVM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
LZS2_k127_752952_0	1254432.SCE1572_07360	7.062e-43	177.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_7529552_2	292563.Cyast_0515	1.042e-24	115.0	COG0277@1|root,COG0277@2|Bacteria,1G176@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS2_k127_7529552_1	1121289.JHVL01000013_gene1663	1.803e-46	183.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia,36HQ2@31979|Clostridiaceae	186801|Clostridia	M	Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans
LZS2_k127_7529552_0	1140.Synpcc7942_1651	3.471e-51	192.0	COG1922@1|root,COG1922@2|Bacteria,1G1AE@1117|Cyanobacteria,1GYVY@1129|Synechococcus	1117|Cyanobacteria	M	Belongs to the glycosyltransferase 26 family	rffM	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
LZS2_k127_7529552_3	1487953.JMKF01000008_gene5992	1.053e-10	66.0	COG1939@1|root,COG1939@2|Bacteria,1G6IR@1117|Cyanobacteria,1HBID@1150|Oscillatoriales	1117|Cyanobacteria	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
LZS2_k127_7536122_2	1304885.AUEY01000019_gene1165	2.114e-56	204.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2WPQK@28221|Deltaproteobacteria,2MKBR@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
LZS2_k127_7536122_0	765952.PUV_13560	1.201e-152	494.0	COG0161@1|root,COG0161@2|Bacteria,2JGX8@204428|Chlamydiae	204428|Chlamydiae	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_7536122_1	1121904.ARBP01000051_gene3624	1.025e-133	434.0	COG0502@1|root,COG0502@2|Bacteria,4NEMA@976|Bacteroidetes,47K22@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
LZS2_k127_7536122_3	348780.NP_2212A	1.081e-07	64.0	arCOG03942@1|root,arCOG03942@2157|Archaea,2XTER@28890|Euryarchaeota,23U83@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7542350_0	118166.JH976537_gene106	2.76e-08	66.0	COG0421@1|root,COG1586@1|root,COG0421@2|Bacteria,COG1586@2|Bacteria,1G36Y@1117|Cyanobacteria,1H85B@1150|Oscillatoriales	1117|Cyanobacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
LZS2_k127_7560873_0	1303518.CCALI_00041	1.315e-127	421.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_7560873_3	536227.CcarbDRAFT_5274	1.452e-17	90.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,36DMA@31979|Clostridiaceae	186801|Clostridia	E	Glutamate formiminotransferase	ftcD	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
LZS2_k127_7560873_2	880071.Fleli_2765	1.236e-49	183.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,47U56@768503|Cytophagia	976|Bacteroidetes	E	Formiminotransferase domain, N-terminal subdomain	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
LZS2_k127_7560873_1	1192034.CAP_6737	1.151e-60	234.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439IS@68525|delta/epsilon subdivisions,2X4V7@28221|Deltaproteobacteria,2YZNY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_7560873_4	1303518.CCALI_02289	2.854e-15	87.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
LZS2_k127_7560873_5	335543.Sfum_3569	4.765e-08	57.0	COG0500@1|root,COG2226@2|Bacteria,1RJ3W@1224|Proteobacteria,42TBV@68525|delta/epsilon subdivisions,2WP3J@28221|Deltaproteobacteria,2MQQ9@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
LZS2_k127_7579342_0	118173.KB235914_gene2667	7.09e-13	78.0	COG0457@1|root,COG0457@2|Bacteria,1G1G9@1117|Cyanobacteria,1H889@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_7581456_0	251221.35212056	5.599e-133	452.0	COG0744@1|root,COG0744@2|Bacteria,1G1XF@1117|Cyanobacteria	1117|Cyanobacteria	M	Penicillin-binding protein, 1A family	mrcB	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
LZS2_k127_7582327_1	234267.Acid_4170	8.31e-41	163.0	2C7G8@1|root,31UU8@2|Bacteria,3Y887@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7582327_0	632335.Calkr_1515	1.285e-60	221.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,42IJP@68295|Thermoanaerobacterales	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,WG_beta_rep
LZS2_k127_75856_0	240016.ABIZ01000001_gene3494	2.488e-154	498.0	COG4941@1|root,COG4941@2|Bacteria,46TPI@74201|Verrucomicrobia,2IV2U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_75856_3	344747.PM8797T_16550	1.608e-48	176.0	COG3795@1|root,COG3795@2|Bacteria,2IZVT@203682|Planctomycetes	203682|Planctomycetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
LZS2_k127_75856_2	1123242.JH636434_gene4561	1.067e-60	212.0	COG3708@1|root,COG3795@1|root,COG3708@2|Bacteria,COG3795@2|Bacteria,2IZ9F@203682|Planctomycetes	203682|Planctomycetes	K	PFAM YCII-related	-	-	-	-	-	-	-	-	-	-	-	-	YCII
LZS2_k127_75856_1	1354722.JQLS01000008_gene3445	2.705e-86	287.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria,46RAQ@74030|Roseovarius	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
LZS2_k127_7588329_0	398512.JQKC01000013_gene1326	3.495e-93	317.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae	186801|Clostridia	C	belongs to the iron- containing alcohol dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
LZS2_k127_7591867_2	570952.ATVH01000020_gene1133	9.363e-149	488.0	COG0500@1|root,COG0500@2|Bacteria,1MWPI@1224|Proteobacteria,2TWAX@28211|Alphaproteobacteria,2JV4A@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7591867_1	331678.Cphamn1_2068	1.469e-194	615.0	COG0372@1|root,COG0372@2|Bacteria,1FD5Z@1090|Chlorobi	1090|Chlorobi	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS2_k127_7591867_0	1128421.JAGA01000002_gene214	1.824e-298	926.0	COG1274@1|root,COG1274@2|Bacteria,2NQRD@2323|unclassified Bacteria	2|Bacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	pckG	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771	4.1.1.32,4.1.1.49	ko:K01596,ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003,M00170	R00341,R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2638	PEPCK_ATP,PEPCK_C,PEPCK_N
LZS2_k127_7594368_1	331869.BAL199_17608	1.651e-16	91.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2TV6U@28211|Alphaproteobacteria,4BS3R@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_7594368_0	316067.Geob_2208	1.79e-67	243.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WMP9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4
LZS2_k127_7600718_1	856793.MICA_1233	2.315e-97	332.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,4BQ3R@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS2_k127_7600718_0	856793.MICA_1232	1.088e-113	375.0	COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,2UJD0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
LZS2_k127_7600718_2	856793.MICA_1231	1.103e-42	159.0	COG0019@1|root,COG0019@2|Bacteria,1Q548@1224|Proteobacteria,2U39J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
LZS2_k127_7601474_0	373994.Riv7116_0523	4.588e-71	255.0	COG1167@1|root,COG1167@2|Bacteria,1G2H6@1117|Cyanobacteria,1HJV0@1161|Nostocales	1117|Cyanobacteria	K	COGs COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
LZS2_k127_7608377_0	1379698.RBG1_1C00001G0110	4.569e-119	395.0	COG0505@1|root,COG0505@2|Bacteria,2NNMS@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1383	CPSase_sm_chain,GATase
LZS2_k127_7608377_1	1203550.HMPREF1475_01527	2.721e-36	145.0	COG0546@1|root,COG0546@2|Bacteria,4NMA5@976|Bacteroidetes,2FMPJ@200643|Bacteroidia	976|Bacteroidetes	V	HAD hydrolase, family IA, variant 1	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS2_k127_7608377_2	411479.BACUNI_03270	6.695e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,4NMG2@976|Bacteroidetes,2FP23@200643|Bacteroidia,4AMJ7@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
LZS2_k127_7608805_1	929556.Solca_2407	1.704e-87	297.0	28M67@1|root,2ZAJW@2|Bacteria,4NF2D@976|Bacteroidetes,1ISM2@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7608805_0	32057.KB217478_gene3939	0.0	1094.0	COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria,1HKKE@1161|Nostocales	1117|Cyanobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
LZS2_k127_7616304_0	395961.Cyan7425_4704	1.057e-150	489.0	COG0542@1|root,COG0542@2|Bacteria,1G0ZH@1117|Cyanobacteria,3KG47@43988|Cyanothece	1117|Cyanobacteria	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_7641359_1	644283.Micau_6029	1.161e-180	577.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4DAJ3@85008|Micromonosporales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB2	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS2_k127_7641359_7	1122602.ATXP01000002_gene793	5.27e-14	81.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,1W7EZ@1268|Micrococcaceae	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	dnaJ	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS2_k127_7641359_4	1297742.A176_05334	2.521e-34	141.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WN9P@28221|Deltaproteobacteria,2Z0H8@29|Myxococcales	28221|Deltaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS2_k127_7641359_2	1134912.AJTV01000020_gene3080	1.554e-41	157.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VF0E@28211|Alphaproteobacteria,36YFG@31993|Methylocystaceae	28211|Alphaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	MA20_44950	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Rhodanese
LZS2_k127_7641359_6	1205910.B005_5060	4.326e-19	95.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EIFM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
LZS2_k127_7641359_9	268407.PWYN_07640	0.0002943	51.0	2EDTW@1|root,337P4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7641359_3	1148.1001362	1.635e-36	140.0	COG0629@1|root,COG0629@2|Bacteria,1G6JH@1117|Cyanobacteria,1H5TE@1142|Synechocystis	1117|Cyanobacteria	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS2_k127_7641359_0	1340493.JNIF01000004_gene829	1.455e-185	595.0	COG0591@1|root,COG0591@2|Bacteria,3Y42K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS2_k127_7641359_5	1120973.AQXL01000135_gene1479	1.519e-26	117.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli,278CY@186823|Alicyclobacillaceae	91061|Bacilli	H	HD domain	yqeK	-	-	-	-	-	-	-	-	-	-	-	HD
LZS2_k127_7641359_8	1122143.AUEG01000001_gene302	2.319e-10	65.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli,27G7J@186828|Carnobacteriaceae	91061|Bacilli	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS2_k127_7658700_0	1122603.ATVI01000010_gene931	3.803e-140	463.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1SYRW@1236|Gammaproteobacteria,1XCQ8@135614|Xanthomonadales	135614|Xanthomonadales	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
LZS2_k127_7658700_2	269797.Mbar_A1366	2.286e-14	83.0	COG0457@1|root,arCOG03045@2157|Archaea,2XVG0@28890|Euryarchaeota	28890|Euryarchaeota	V	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_7658700_1	240016.ABIZ01000001_gene5926	5.725e-75	267.0	2DR4U@1|root,33A62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CreD
LZS2_k127_7658700_4	765912.Thimo_2552	1.345e-06	58.0	COG0810@1|root,COG0810@2|Bacteria,1R330@1224|Proteobacteria,1RQAX@1236|Gammaproteobacteria,1WWP5@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS2_k127_7658700_3	251221.35213978	6.301e-09	65.0	COG0810@1|root,COG1714@1|root,COG0810@2|Bacteria,COG1714@2|Bacteria,1GQMS@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM TonB family C-terminal domain	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	RDD,TonB_2
LZS2_k127_7661901_1	743720.Psefu_2369	1.723e-41	162.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,1RPGI@1236|Gammaproteobacteria,1YWQK@136845|Pseudomonas putida group	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS2_k127_7661901_0	406124.ACPC01000048_gene258	1.069e-60	224.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4HDG0@91061|Bacilli,1ZBE9@1386|Bacillus	91061|Bacilli	C	Belongs to the citrate synthase family	citA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS2_k127_7662012_1	1536772.R70723_10040	1.077e-71	259.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli,26QIQ@186822|Paenibacillaceae	91061|Bacilli	S	Hemolysins and related proteins containing CBS domains	corC1	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
LZS2_k127_7662012_0	886293.Sinac_7521	6.931e-104	357.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Pur_ac_phosph_N,SLH
LZS2_k127_7668318_4	485913.Krac_0651	8.308e-26	108.0	COG1397@1|root,COG1397@2|Bacteria,2G7F9@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ADP-ribosylation Crystallin J1	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
LZS2_k127_7668318_5	1303518.CCALI_01464	2.252e-19	95.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0071704,GO:1901564	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS2_k127_7668318_3	1321778.HMPREF1982_03937	6.469e-34	135.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,269MZ@186813|unclassified Clostridiales	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
LZS2_k127_7668318_2	1282361.ABAC402_00585	3.865e-38	164.0	COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TY72@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SSF
LZS2_k127_7668318_6	1128427.KB904821_gene2524	2.794e-12	70.0	COG1314@1|root,COG1314@2|Bacteria,1G92B@1117|Cyanobacteria,1HCV7@1150|Oscillatoriales	1117|Cyanobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
LZS2_k127_7668318_0	986075.CathTA2_1622	2.417e-52	193.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli	91061|Bacilli	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
LZS2_k127_7668318_1	945713.IALB_0344	2.759e-49	186.0	COG0763@1|root,COG0763@2|Bacteria	2|Bacteria	M	lipid-A-disaccharide synthase activity	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
LZS2_k127_7671325_2	358681.BBR47_14930	4.026e-35	145.0	COG0330@1|root,COG0330@2|Bacteria,1UZJK@1239|Firmicutes,4HGVU@91061|Bacilli,26RE7@186822|Paenibacillaceae	91061|Bacilli	O	HflC protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_7671325_3	1461580.CCAS010000086_gene4344	3.288e-34	144.0	COG0330@1|root,COG0330@2|Bacteria,1TT9B@1239|Firmicutes,4HESZ@91061|Bacilli,1ZF31@1386|Bacillus	91061|Bacilli	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_7671325_0	28072.Nos7524_2689	3.279e-89	312.0	COG1167@1|root,COG1167@2|Bacteria,1G2H6@1117|Cyanobacteria,1HJV0@1161|Nostocales	1117|Cyanobacteria	K	COGs COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
LZS2_k127_7671325_5	457570.Nther_1203	6.208e-14	82.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
LZS2_k127_7671325_6	888055.HMPREF9015_00645	1.126e-13	81.0	COG0295@1|root,COG0295@2|Bacteria,37ADA@32066|Fusobacteria	32066|Fusobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
LZS2_k127_7671325_1	706587.Desti_0504	4.471e-49	184.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,42MSW@68525|delta/epsilon subdivisions,2WNY3@28221|Deltaproteobacteria,2MRTF@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
LZS2_k127_7671325_4	65393.PCC7424_3507	2.415e-23	105.0	2D2K4@1|root,32TD0@2|Bacteria,1G611@1117|Cyanobacteria,3KIM5@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function (DUF3124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3124
LZS2_k127_7673505_1	794903.OPIT5_04410	9.109e-20	93.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
LZS2_k127_7673505_0	713586.KB900536_gene1524	9.584e-141	458.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RMP7@1236|Gammaproteobacteria,1X1AI@135613|Chromatiales	135613|Chromatiales	S	HipA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HipA_C
LZS2_k127_7675087_2	398512.JQKC01000021_gene3755	0.0008791	47.0	2E7I0@1|root,3392W@2|Bacteria,1VHT0@1239|Firmicutes,24U7T@186801|Clostridia,3WKGD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7675087_1	1120973.AQXL01000132_gene2153	1.833e-25	121.0	COG0737@1|root,COG3103@1|root,COG0737@2|Bacteria,COG4991@2|Bacteria,1UM5I@1239|Firmicutes,4ITQI@91061|Bacilli,279SF@186823|Alicyclobacillaceae	91061|Bacilli	T	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
LZS2_k127_7675087_0	370438.PTH_2754	1.715e-44	169.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,261QJ@186807|Peptococcaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
LZS2_k127_7675489_1	111781.Lepto7376_0227	1.145e-36	147.0	COG0497@1|root,COG0497@2|Bacteria,1G0D4@1117|Cyanobacteria,1H7ME@1150|Oscillatoriales	1117|Cyanobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
LZS2_k127_7675489_0	1379698.RBG1_1C00001G0517	1.292e-105	353.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
LZS2_k127_7677523_2	706587.Desti_0144	3.172e-111	368.0	COG0451@1|root,COG0451@2|Bacteria,1RBIE@1224|Proteobacteria	1224|Proteobacteria	GM	Epimerase dehydratase	-	-	1.1.1.339	ko:K19180	ko00523,ko01130,map00523,map01130	-	R10190	RC00182	ko00000,ko00001,ko01000	-	-	-	Epimerase
LZS2_k127_7677523_1	706587.Desti_0145	8.533e-125	409.0	2BM4B@1|root,32FMP@2|Bacteria,1R8PD@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
LZS2_k127_7677523_0	706587.Desti_0146	3.872e-136	445.0	COG0457@1|root,COG0457@2|Bacteria,1QW33@1224|Proteobacteria,42R6C@68525|delta/epsilon subdivisions,2X8GD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM TIGR03032 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915
LZS2_k127_7677971_0	926569.ANT_15160	1.446e-42	165.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
LZS2_k127_7677971_1	1157490.EL26_21110	2.334e-35	152.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_7688840_0	1267534.KB906754_gene2904	2.341e-33	139.0	28M5B@1|root,2ZAJ4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7698445_0	1392491.JIAE01000001_gene139	3.031e-06	58.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3WGCA@541000|Ruminococcaceae	186801|Clostridia	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyltransferase,Condensation,NAD_binding_4,PP-binding
LZS2_k127_7703297_1	338966.Ppro_2157	5.686e-06	58.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7703297_2	1089544.KB912942_gene140	3.669e-05	57.0	COG2199@1|root,COG3706@2|Bacteria,2IA4H@201174|Actinobacteria,4E1Q9@85010|Pseudonocardiales	201174|Actinobacteria	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
LZS2_k127_7703297_0	926569.ANT_11490	4.517e-11	72.0	COG1807@1|root,COG1807@2|Bacteria,2G9HX@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7715028_2	886293.Sinac_0760	1.001e-50	188.0	COG4619@1|root,COG4619@2|Bacteria,2J340@203682|Planctomycetes	203682|Planctomycetes	S	transport system ATPase component	-	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
LZS2_k127_7715028_1	886293.Sinac_0759	9.604e-80	274.0	COG0390@1|root,COG0390@2|Bacteria,2J0PF@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterised protein family (UPF0014)	-	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
LZS2_k127_7715028_0	663610.JQKO01000001_gene622	1.591e-244	761.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,3NAFW@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	Sulfatase	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase,Sulfatase_C
LZS2_k127_7716373_1	1123261.AXDW01000021_gene859	1.108e-43	163.0	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,1S4EZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	phenylacetic acid degradation protein	paaI	GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iBWG_1329.BWG_1225,iEC55989_1330.EC55989_1532,iECDH10B_1368.ECDH10B_1521,iECDH1ME8569_1439.EcDH1_2249,iECIAI1_1343.ECIAI1_1396,iECO103_1326.ECO103_1533,iECO111_1330.ECO111_1790,iECO26_1355.ECO26_2000,iECSE_1348.ECSE_1481,iEKO11_1354.EKO11_2417,iETEC_1333.ETEC_1471,iEcDH1_1363.EcDH1_2249,iEcE24377_1341.EcE24377A_1581,iEcHS_1320.EcHS_A1483,iEcolC_1368.EcolC_2259,iUMNK88_1353.UMNK88_1803,iY75_1357.Y75_RS07340	4HBT
LZS2_k127_7716373_0	99598.Cal7507_3974	2.761e-100	332.0	COG1028@1|root,COG1028@2|Bacteria,1G3Y3@1117|Cyanobacteria,1HRRJ@1161|Nostocales	1117|Cyanobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
LZS2_k127_7716373_5	2880.D7FWZ8	0.0004452	51.0	COG0457@1|root,KOG1840@2759|Eukaryota	2759|Eukaryota	C	determination of stomach left/right asymmetry	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,NACHT,TIG,TPR_10,TPR_12
LZS2_k127_7716373_2	452637.Oter_0307	2.071e-36	149.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
LZS2_k127_7716373_3	195250.CM001776_gene3762	3.395e-30	121.0	COG3369@1|root,COG3369@2|Bacteria,1G7ZE@1117|Cyanobacteria,1H4B8@1129|Synechococcus	1117|Cyanobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
LZS2_k127_7728236_0	1125863.JAFN01000001_gene308	1.866e-245	788.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
LZS2_k127_7728236_4	1304885.AUEY01000006_gene717	2.923e-56	205.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2WJ6C@28221|Deltaproteobacteria,2MI5J@213118|Desulfobacterales	28221|Deltaproteobacteria	F	CobB/CobQ-like glutamine amidotransferase domain	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
LZS2_k127_7728236_2	765869.BDW_11060	9.144e-74	260.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2MTT1@213481|Bdellovibrionales,2WIXY@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
LZS2_k127_7728236_1	1449126.JQKL01000015_gene2922	2.015e-124	416.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,267XC@186813|unclassified Clostridiales	186801|Clostridia	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS04230	AICARFT_IMPCHas,MGS
LZS2_k127_7728236_3	1266925.JHVX01000003_gene522	1.561e-59	211.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,372ZQ@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
LZS2_k127_7728236_5	880070.Cycma_1771	4.258e-09	59.0	COG0026@1|root,COG0026@2|Bacteria,4NEGE@976|Bacteroidetes,47JH8@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
LZS2_k127_7730861_2	1094980.Mpsy_2824	4.811e-06	54.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,arCOG02349@1|root,arCOG02352@1|root,arCOG02376@1|root,arCOG04001@1|root,arCOG02349@2157|Archaea,arCOG02352@2157|Archaea,arCOG02357@2157|Archaea,arCOG02376@2157|Archaea,arCOG02391@2157|Archaea,arCOG02591@2157|Archaea,arCOG04001@2157|Archaea,arCOG06918@2157|Archaea,2Y82D@28890|Euryarchaeota,2NBNN@224756|Methanomicrobia	2157|Archaea	T	Histidine Phosphotransfer domain	-	-	-	ko:K03413,ko:K07662,ko:K07667,ko:K11443	ko01503,ko02020,ko02024,ko02030,ko04112,map01503,map02020,map02024,map02030,map04112	M00447,M00454,M00506,M00511,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_7730861_0	102232.GLO73106DRAFT_00019380	1.635e-55	208.0	COG0642@1|root,COG2205@2|Bacteria,1G06C@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS2_k127_7730861_1	585394.RHOM_00330	4.275e-12	70.0	COG4819@1|root,COG4819@2|Bacteria,1TQ6T@1239|Firmicutes,24BB7@186801|Clostridia	186801|Clostridia	E	PFAM Ethanolamine utilisation	eutA	-	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
LZS2_k127_7741502_6	330214.NIDE4386	3.039e-23	105.0	COG1009@1|root,COG1009@2|Bacteria,3J0AN@40117|Nitrospirae	40117|Nitrospirae	CP	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00341,ko:K05577	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
LZS2_k127_7741502_10	1123236.KB899381_gene2959	5.965e-09	65.0	COG0288@1|root,COG0288@2|Bacteria,1MV1U@1224|Proteobacteria,1SYDI@1236|Gammaproteobacteria,464WD@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Reversible hydration of carbon dioxide	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009439,GO:0009440,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901565,GO:1901575	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	iJN746.PP_0100	Pro_CA
LZS2_k127_7741502_9	309801.trd_0059	3.734e-11	74.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi,27XZI@189775|Thermomicrobia	189775|Thermomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_7741502_7	521674.Plim_2025	1.014e-15	81.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Methyltransf_11
LZS2_k127_7741502_5	1122165.AUHS01000015_gene749	8.128e-24	105.0	COG0640@1|root,COG0640@2|Bacteria,1QCA7@1224|Proteobacteria,1T7ZW@1236|Gammaproteobacteria,1JG33@118969|Legionellales	118969|Legionellales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7741502_4	518766.Rmar_0627	2.795e-74	263.0	COG0167@1|root,COG0167@2|Bacteria,4NDVB@976|Bacteroidetes,1FISR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS2_k127_7741502_8	215803.DB30_6255	2.599e-11	75.0	COG0515@1|root,COG2114@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWIA@29|Myxococcales	1224|Proteobacteria	KLT	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,Pkinase
LZS2_k127_7741502_0	926554.KI912637_gene3211	6.427e-211	662.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1WKJP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CF	dihydroorotate dehydrogenase	pyrD	-	1.3.1.1,1.3.1.14	ko:K17723,ko:K17828	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01869,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21
LZS2_k127_7741502_1	1122221.JHVI01000023_gene473	7.079e-169	542.0	COG0493@1|root,COG0493@2|Bacteria,1WJAP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG0493 NADPH-dependent glutamate synthase beta chain and related	-	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
LZS2_k127_7741502_2	234267.Acid_7663	9.137e-140	451.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
LZS2_k127_7741502_3	867903.ThesuDRAFT_01061	9.536e-140	456.0	COG0160@1|root,COG0160@2|Bacteria,1VS6F@1239|Firmicutes,24YI0@186801|Clostridia	186801|Clostridia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_774439_3	5341.XP_007325795.1	7.088e-05	48.0	COG0526@1|root,KOG0907@2759|Eukaryota,3A886@33154|Opisthokonta,3P5A0@4751|Fungi,3V2Q4@5204|Basidiomycota,229AD@155619|Agaricomycetes,3W71Y@5338|Agaricales	4751|Fungi	O	Thioredoxin	TRX3	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_774439_2	1123278.KB893562_gene3243	5.735e-05	51.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,47JS4@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
LZS2_k127_774439_0	237368.SCABRO_02318	3.856e-21	103.0	COG0457@1|root,COG0457@2|Bacteria	237368.SCABRO_02318|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_774439_1	1100720.ALKN01000045_gene309	6.388e-09	61.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,4A9PX@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS2_k127_7754156_1	1379698.RBG1_1C00001G0735	2.812e-98	329.0	COG0396@1|root,COG0396@2|Bacteria,2NNYE@2323|unclassified Bacteria	2|Bacteria	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
LZS2_k127_7754156_0	1379698.RBG1_1C00001G0736	4.864e-234	731.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
LZS2_k127_7754156_2	479434.Sthe_1524	1.025e-06	55.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
LZS2_k127_7761085_0	479434.Sthe_0441	2.212e-158	508.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi,27XEJ@189775|Thermomicrobia	189775|Thermomicrobia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS2_k127_7761085_1	1395587.P364_0108770	1.791e-32	132.0	COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,4HAA2@91061|Bacilli,26SUB@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
LZS2_k127_7767746_1	91604.ID47_01130	1.306e-11	66.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2TUNY@28211|Alphaproteobacteria,47FWE@766|Rickettsiales	766|Rickettsiales	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7767746_3	123214.PERMA_0503	0.000336	52.0	COG0457@1|root,COG0457@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_7767746_0	1487953.JMKF01000028_gene1254	3.043e-217	689.0	COG0488@1|root,COG0488@2|Bacteria,1G14R@1117|Cyanobacteria,1H8Q8@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG0488 ATPase components of ABC transporter with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
LZS2_k127_7767746_2	595460.RRSWK_06447	4.487e-11	66.0	COG1680@1|root,COG3509@1|root,COG1680@2|Bacteria,COG3509@2|Bacteria,2J04W@203682|Planctomycetes	203682|Planctomycetes	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
LZS2_k127_7771994_1	272134.KB731324_gene6543	1.272e-49	188.0	COG5002@1|root,COG5002@2|Bacteria,1G133@1117|Cyanobacteria,1H7HP@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11520	ko02020,map02020	M00465	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
LZS2_k127_7771994_2	221288.JH992901_gene643	2.082e-31	139.0	COG0457@1|root,COG0457@2|Bacteria,1G0N0@1117|Cyanobacteria	1117|Cyanobacteria	S	tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_7771994_0	1174528.JH992898_gene2951	1.197e-90	310.0	COG0282@1|root,COG0282@2|Bacteria,1G214@1117|Cyanobacteria,1JIEM@1189|Stigonemataceae	1117|Cyanobacteria	C	Acetokinase family	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
LZS2_k127_7773520_1	648996.Theam_1520	2.925e-128	426.0	COG0215@1|root,COG0215@2|Bacteria,2G3JG@200783|Aquificae	200783|Aquificae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
LZS2_k127_7773520_0	648996.Theam_0502	2.388e-136	450.0	COG0008@1|root,COG0008@2|Bacteria,2G3SV@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
LZS2_k127_7773520_2	631454.N177_2246	1.651e-28	125.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2UBTC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
LZS2_k127_7786393_2	1128421.JAGA01000002_gene1898	6.578e-11	66.0	COG1716@1|root,COG1716@2|Bacteria,2NRHK@2323|unclassified Bacteria	2|Bacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
LZS2_k127_7786393_0	273068.TTE1501	2.451e-50	188.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,42EM8@68295|Thermoanaerobacterales	186801|Clostridia	T	protein phosphatase 2C domain protein	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS2_k127_7786393_1	1527444.ucyna2_01060	1.448e-44	176.0	COG0661@1|root,COG0661@2|Bacteria,1G0X9@1117|Cyanobacteria	1117|Cyanobacteria	S	Unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
LZS2_k127_7794343_0	1170562.Cal6303_4117	3.018e-168	544.0	COG0542@1|root,COG0542@2|Bacteria,1G40E@1117|Cyanobacteria,1HK82@1161|Nostocales	1117|Cyanobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_7800352_0	231434.JQJH01000001_gene1691	7.627e-57	203.0	COG0656@1|root,COG0656@2|Bacteria,1PENK@1224|Proteobacteria,2V8CZ@28211|Alphaproteobacteria,3NCS5@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_7800352_1	237368.SCABRO_01475	2.009e-23	104.0	COG1301@1|root,COG1301@2|Bacteria	2|Bacteria	C	dicarboxylic acid transport	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
LZS2_k127_7811541_0	754252.PFREUD_19610	3.736e-22	111.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4DNY6@85009|Propionibacteriales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_7811541_1	243230.DR_1971	2.441e-15	88.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_7824885_0	448385.sce7178	1.568e-59	216.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,42MR3@68525|delta/epsilon subdivisions,2WKWG@28221|Deltaproteobacteria,2YTTA@29|Myxococcales	28221|Deltaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
LZS2_k127_7824885_1	1242864.D187_010412	2.733e-37	149.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,42MR3@68525|delta/epsilon subdivisions,2WKWG@28221|Deltaproteobacteria,2YTTA@29|Myxococcales	28221|Deltaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
LZS2_k127_7834314_1	926569.ANT_14890	1.992e-19	100.0	COG2267@1|root,COG2267@2|Bacteria,2G6QC@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_7834314_0	74547.PMT_0296	4.636e-34	147.0	COG0457@1|root,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1MM8U@1212|Prochloraceae	1117|Cyanobacteria	O	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_8
LZS2_k127_7834896_0	351627.Csac_1030	1.874e-114	377.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,42F1U@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS2_k127_7834896_2	743525.TSC_c17860	1.76e-07	63.0	COG0793@1|root,COG0793@2|Bacteria,1WIKF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS2_k127_7834896_1	880073.Calab_3570	4.365e-34	140.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
LZS2_k127_7835829_3	1324957.K933_09432	2.829e-12	75.0	COG4552@1|root,arCOG10664@2157|Archaea,2XTW3@28890|Euryarchaeota,23S97@183963|Halobacteria	183963|Halobacteria	S	acetyltransferase involved in intracellular survival and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
LZS2_k127_7835829_2	1123284.KB899053_gene2103	5.414e-27	117.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,26PQ3@186821|Sporolactobacillaceae	91061|Bacilli	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
LZS2_k127_7835829_1	1183438.GKIL_2726	1.141e-28	121.0	COG0736@1|root,COG0736@2|Bacteria,1G6YV@1117|Cyanobacteria	1117|Cyanobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
LZS2_k127_7835829_0	667014.Thein_2162	3.29e-59	215.0	COG1912@1|root,COG1912@2|Bacteria,2GHAQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
LZS2_k127_7838569_0	744872.Spica_0349	3.967e-12	73.0	COG3654@1|root,COG3654@2|Bacteria,2J7Z6@203691|Spirochaetes	203691|Spirochaetes	S	Death-on-curing protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
LZS2_k127_7841966_1	694429.Pyrfu_1617	1.951e-09	62.0	COG0456@1|root,arCOG00833@2157|Archaea,2XQJH@28889|Crenarchaeota	28889|Crenarchaeota	S	TIGRFAM ribosomal-protein-alanine acetyltransferase	-	GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
LZS2_k127_7841966_0	886293.Sinac_0075	8.146e-184	582.0	COG0626@1|root,COG0626@2|Bacteria,2IYGK@203682|Planctomycetes	203682|Planctomycetes	E	Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
LZS2_k127_7846036_0	509191.AEDB02000020_gene3389	6.349e-66	240.0	COG1061@1|root,COG1061@2|Bacteria,1TRA8@1239|Firmicutes,2481H@186801|Clostridia,3WNCQ@541000|Ruminococcaceae	186801|Clostridia	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
LZS2_k127_7849472_0	1089553.Tph_c14230	2.76e-53	211.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_7849472_1	883078.HMPREF9695_03659	3.624e-44	174.0	COG1525@1|root,COG1525@2|Bacteria,1R7Y7@1224|Proteobacteria,2U2IA@28211|Alphaproteobacteria,3JSDZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
LZS2_k127_7849472_2	644281.MFS40622_0480	2.728e-05	56.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota	2157|Archaea	O	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
LZS2_k127_7852274_2	484770.UFO1_3756	5.096e-06	55.0	COG4818@1|root,COG4818@2|Bacteria,1VBIZ@1239|Firmicutes,4H882@909932|Negativicutes	909932|Negativicutes	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7852274_0	469596.HMPREF9488_03626	5.991e-48	179.0	COG1670@1|root,COG1670@2|Bacteria,1V54D@1239|Firmicutes	1239|Firmicutes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
LZS2_k127_7852274_1	1353528.DT23_12025	5.927e-12	74.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,2TUBP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
LZS2_k127_7854342_0	56110.Oscil6304_2456	8.414e-234	751.0	COG0013@1|root,COG0013@2|Bacteria,1G0NP@1117|Cyanobacteria,1H8XC@1150|Oscillatoriales	1117|Cyanobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS2_k127_7854342_1	644282.Deba_1407	8.73e-38	145.0	COG0328@1|root,COG0328@2|Bacteria,1MZD1@1224|Proteobacteria,42UI6@68525|delta/epsilon subdivisions,2WQSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Ribonuclease H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
LZS2_k127_7860350_0	522306.CAP2UW1_1124	1.104e-109	358.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,2VJKF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
LZS2_k127_7860350_1	1123508.JH636439_gene753	1.881e-41	168.0	2DBS0@1|root,2ZANT@2|Bacteria,2IY4P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7860350_2	1122915.AUGY01000157_gene550	5.914e-21	104.0	COG0451@1|root,COG0451@2|Bacteria,1V0AK@1239|Firmicutes,4HQJU@91061|Bacilli,26QTQ@186822|Paenibacillaceae	91061|Bacilli	GM	NAD-dependent epimerase	ytbQ	-	1.1.1.203,1.1.1.388	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R10520,R10841,R10907	RC00066	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS2_k127_7860350_3	1049564.TevJSym_bp00200	8.824e-09	66.0	2EH3D@1|root,33AVD@2|Bacteria,1NHJ1@1224|Proteobacteria,1SIF3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
LZS2_k127_7866423_0	1121377.KB906403_gene3107	1.766e-95	322.0	COG0059@1|root,COG0059@2|Bacteria,1WIFD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
LZS2_k127_7873497_0	1173021.ALWA01000020_gene240	1.685e-46	173.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_7873497_1	3067.XP_002949373.1	6.974e-35	136.0	COG1233@1|root,2QSIC@2759|Eukaryota,37N2T@33090|Viridiplantae,34H3F@3041|Chlorophyta	3041|Chlorophyta	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS2_k127_7882826_1	911008.GLAD_00216	1.994e-11	77.0	COG2885@1|root,COG2885@2|Bacteria,1P1AB@1224|Proteobacteria,1RMCQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA
LZS2_k127_7882826_0	1198452.Jab_2c01130	8.923e-30	136.0	COG3511@1|root,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Phosphoesterase
LZS2_k127_7887847_1	321327.CYA_0543	2.56e-28	122.0	COG0373@1|root,COG0373@2|Bacteria,1G04R@1117|Cyanobacteria,1GYRG@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS2_k127_7887847_0	1120973.AQXL01000116_gene281	1.063e-76	267.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,278YD@186823|Alicyclobacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
LZS2_k127_7895505_0	497965.Cyan7822_5346	6.217e-143	468.0	COG4320@1|root,COG4320@2|Bacteria,1G0BG@1117|Cyanobacteria,3KJ94@43988|Cyanothece	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
LZS2_k127_7895505_2	1313421.JHBV01000014_gene3869	6.758e-05	55.0	COG0793@1|root,COG0793@2|Bacteria,4NDWU@976|Bacteroidetes,1IQA9@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS2_k127_7895505_1	483219.LILAB_35130	3.801e-35	139.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2WPSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
LZS2_k127_7909542_2	756067.MicvaDRAFT_0520	6.928e-21	96.0	COG0477@1|root,COG2814@2|Bacteria,1G0DP@1117|Cyanobacteria,1H9H2@1150|Oscillatoriales	1117|Cyanobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_7909542_0	401526.TcarDRAFT_0101	5.996e-76	263.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes	909932|Negativicutes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep,Hexapep_2
LZS2_k127_7909542_1	1121423.JONT01000003_gene998	9.174e-49	179.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,261X9@186807|Peptococcaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
LZS2_k127_7910408_1	1173026.Glo7428_3079	1.158e-98	336.0	28JJV@1|root,2Z9CT@2|Bacteria,1G4MM@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7910408_0	1173026.Glo7428_3080	2.579e-123	402.0	COG1857@1|root,COG1857@2|Bacteria,1G004@1117|Cyanobacteria	1117|Cyanobacteria	L	CRISPR-associated protein Cas7 Cst2 DevR, subtype I-B TNEAP	-	-	-	ko:K19075	-	-	-	-	ko00000,ko02048	-	-	-	DevR
LZS2_k127_7910408_2	1173026.Glo7428_3081	5.475e-73	252.0	2DE3P@1|root,2ZKD1@2|Bacteria,1G5QI@1117|Cyanobacteria	1117|Cyanobacteria	S	CRISPR-associated protein (Cas_Cas5)	-	-	-	ko:K19090	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
LZS2_k127_7913074_0	1396141.BATP01000056_gene3277	4.294e-40	161.0	COG3209@1|root,COG3209@2|Bacteria,46TP7@74201|Verrucomicrobia,2IVDA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
LZS2_k127_7913074_1	1219045.BV98_000638	1.636e-32	127.0	COG3041@1|root,COG3041@2|Bacteria,1N0K0@1224|Proteobacteria,2UC2Y@28211|Alphaproteobacteria,2K6W6@204457|Sphingomonadales	204457|Sphingomonadales	S	Addiction module	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
LZS2_k127_7913074_2	713587.THITH_02180	1.378e-27	114.0	COG3077@1|root,COG3077@2|Bacteria,1NA1R@1224|Proteobacteria,1SF32@1236|Gammaproteobacteria,1X16Y@135613|Chromatiales	135613|Chromatiales	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
LZS2_k127_7913074_3	240016.ABIZ01000001_gene5673	6.176e-07	57.0	COG3209@1|root,COG3209@2|Bacteria,46VWR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,RHS_repeat
LZS2_k127_7915054_0	243231.GSU1123	3.77e-54	199.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria,43TZB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_7915054_1	1380394.JADL01000007_gene4472	8.37e-33	132.0	COG0824@1|root,COG0824@2|Bacteria,1MZFI@1224|Proteobacteria,2U5Q6@28211|Alphaproteobacteria,2JTTU@204441|Rhodospirillales	204441|Rhodospirillales	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
LZS2_k127_7915054_2	215803.DB30_5360	9.397e-24	111.0	2EKVR@1|root,33EJ9@2|Bacteria,1Q2HX@1224|Proteobacteria,4384Q@68525|delta/epsilon subdivisions,2X9XE@28221|Deltaproteobacteria,2YVRC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7915708_0	886293.Sinac_6412	2.181e-65	239.0	COG0520@1|root,COG0520@2|Bacteria,2IXCD@203682|Planctomycetes	203682|Planctomycetes	E	selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS2_k127_7915708_1	1444309.JAQG01000054_gene845	9.819e-54	195.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli,26R6D@186822|Paenibacillaceae	91061|Bacilli	C	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively	iolA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_7916570_1	525268.HMPREF0308_1045	4.813e-23	106.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,22N00@1653|Corynebacteriaceae	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
LZS2_k127_7916570_0	562970.Btus_1758	1.061e-51	190.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4HFZX@91061|Bacilli,2789X@186823|Alicyclobacillaceae	91061|Bacilli	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
LZS2_k127_7916570_3	936589.HMPREF1521_0528	2.19e-05	56.0	2E382@1|root,32Y7S@2|Bacteria,1VF4Z@1239|Firmicutes,4H5V7@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7916570_2	933262.AXAM01000034_gene1565	3.439e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2MJAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8,zinc_ribbon_4
LZS2_k127_7923542_0	1173027.Mic7113_5559	3.073e-262	852.0	COG0085@1|root,COG0085@2|Bacteria,1G14Y@1117|Cyanobacteria,1H8TE@1150|Oscillatoriales	1117|Cyanobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
LZS2_k127_7928323_2	552811.Dehly_0851	4.21e-09	60.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	fdnT	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
LZS2_k127_7928323_0	251221.35212421	6.506e-259	814.0	COG0556@1|root,COG0556@2|Bacteria,1G05H@1117|Cyanobacteria	1117|Cyanobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
LZS2_k127_7928323_1	215803.DB30_3173	1.04e-140	465.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
LZS2_k127_793379_2	768672.Desfe_0055	1.412e-08	60.0	COG1148@1|root,arCOG10656@2157|Archaea,2XS37@28889|Crenarchaeota	28889|Crenarchaeota	C	COGs COG1148 Heterodisulfide reductase subunit A and related polyferredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_793379_1	794903.OPIT5_19275	3.85e-51	190.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,46VST@74201|Verrucomicrobia,3K7DE@414999|Opitutae	414999|Opitutae	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Oxidored_q6
LZS2_k127_793379_0	1121396.KB892924_gene623	1.012e-74	263.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,2MHME@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
LZS2_k127_7936842_0	529818.AMSG_02192T0	9.078e-06	57.0	KOG1947@1|root,KOG1947@2759|Eukaryota	2759|Eukaryota	B	F-box LRR-repeat protein	FBXL7	GO:0000086,GO:0000151,GO:0000209,GO:0000278,GO:0003002,GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0005911,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0007049,GO:0007275,GO:0007346,GO:0007389,GO:0007444,GO:0007447,GO:0007449,GO:0008150,GO:0008152,GO:0008283,GO:0009056,GO:0009057,GO:0009888,GO:0009954,GO:0009966,GO:0009967,GO:0009987,GO:0010265,GO:0010389,GO:0010498,GO:0010564,GO:0010646,GO:0010647,GO:0010948,GO:0010972,GO:0015630,GO:0016043,GO:0016567,GO:0016740,GO:0019005,GO:0019538,GO:0019787,GO:0019941,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030054,GO:0030163,GO:0031146,GO:0031461,GO:0032446,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032991,GO:0035295,GO:0035330,GO:0035332,GO:0036211,GO:0040008,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043632,GO:0043687,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044839,GO:0045177,GO:0045570,GO:0045571,GO:0045786,GO:0045926,GO:0045930,GO:0046620,GO:0046621,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048638,GO:0048640,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051239,GO:0051241,GO:0051603,GO:0051726,GO:0060429,GO:0065003,GO:0065007,GO:0070647,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902494,GO:1902531,GO:1902533,GO:1902749,GO:1902750,GO:1903047,GO:1990234,GO:2000026	-	ko:K10268,ko:K10273	-	-	-	-	ko00000,ko04121	-	-	-	F-box-like,LRR_1,LRR_6
LZS2_k127_7945372_0	1499967.BAYZ01000016_gene6546	5.991e-37	160.0	COG0383@1|root,COG0383@2|Bacteria,2NQ98@2323|unclassified Bacteria	2|Bacteria	G	Alpha mannosidase, middle domain	mngB	GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564	2.3.1.204,3.2.1.170,3.2.1.24	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	iEcolC_1368.EcolC_2924,iSF_1195.SF0565,iSFxv_1172.SFxv_0623,iS_1188.S0578	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
LZS2_k127_7956412_2	181119.XP_005532233.1	7.082e-05	53.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria,482US@7711|Chordata,49452@7742|Vertebrata,4GNZA@8782|Aves	33208|Metazoa	M	ZU5 domain	ANK2	GO:0000902,GO:0000904,GO:0001508,GO:0002027,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003205,GO:0003230,GO:0003279,GO:0003283,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005911,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006888,GO:0006928,GO:0006935,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0007009,GO:0007154,GO:0007165,GO:0007267,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007507,GO:0008015,GO:0008016,GO:0008092,GO:0008104,GO:0008150,GO:0009605,GO:0009653,GO:0009893,GO:0009987,GO:0010171,GO:0010256,GO:0010468,GO:0010522,GO:0010604,GO:0010628,GO:0010646,GO:0010880,GO:0010881,GO:0010882,GO:0010959,GO:0014069,GO:0014704,GO:0015459,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016247,GO:0016323,GO:0016328,GO:0019222,GO:0019722,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0022008,GO:0022898,GO:0023051,GO:0023052,GO:0030001,GO:0030003,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030048,GO:0030054,GO:0030154,GO:0030182,GO:0030315,GO:0030507,GO:0030674,GO:0031175,GO:0031224,GO:0031226,GO:0031430,GO:0031647,GO:0031672,GO:0031674,GO:0032279,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032879,GO:0032970,GO:0032989,GO:0032990,GO:0033036,GO:0033292,GO:0033365,GO:0033563,GO:0034394,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035556,GO:0035637,GO:0036309,GO:0036371,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042592,GO:0042692,GO:0043034,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043292,GO:0044057,GO:0044093,GO:0044291,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044464,GO:0045202,GO:0045927,GO:0046907,GO:0048193,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048522,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050821,GO:0050839,GO:0050896,GO:0051049,GO:0051050,GO:0051094,GO:0051117,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051279,GO:0051282,GO:0051641,GO:0051649,GO:0051716,GO:0051899,GO:0051924,GO:0051928,GO:0055001,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055117,GO:0060047,GO:0060048,GO:0060090,GO:0060255,GO:0060306,GO:0060307,GO:0060341,GO:0061024,GO:0061061,GO:0061337,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070252,GO:0070296,GO:0070727,GO:0070838,GO:0070972,GO:0071840,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0072657,GO:0072659,GO:0086001,GO:0086002,GO:0086003,GO:0086004,GO:0086005,GO:0086010,GO:0086012,GO:0086014,GO:0086015,GO:0086018,GO:0086019,GO:0086026,GO:0086036,GO:0086046,GO:0086065,GO:0086066,GO:0086070,GO:0086091,GO:0090257,GO:0097458,GO:0097485,GO:0098590,GO:0098771,GO:0098772,GO:0098794,GO:0098900,GO:0098901,GO:0098904,GO:0098907,GO:0098910,GO:0098984,GO:0099080,GO:0099081,GO:0099106,GO:0099512,GO:0099572,GO:0099623,GO:0120036,GO:0120039,GO:1901016,GO:1901018,GO:1901019,GO:1901021,GO:1901379,GO:1901381,GO:1903115,GO:1903169,GO:1903522,GO:1903779,GO:1904062,GO:1904064,GO:1904427,GO:1990778,GO:2001257,GO:2001259	-	ko:K10380,ko:K21440	ko04624,ko05205,map04624,map05205	-	-	-	ko00000,ko00001,ko04131,ko04812	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,Death,ZU5
LZS2_k127_7956412_1	443143.GM18_0109	2.437e-05	56.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
LZS2_k127_7956412_0	3880.AES75115	2.992e-14	85.0	COG2267@1|root,KOG1455@2759|Eukaryota,37IA3@33090|Viridiplantae,3G92D@35493|Streptophyta,4JMA9@91835|fabids	35493|Streptophyta	I	Monoglyceride	-	-	3.1.1.23	ko:K01054	ko00561,ko01100,ko04714,ko04723,ko04923,map00561,map01100,map04714,map04723,map04923	M00098	R01351	RC00020,RC00041	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Hydrolase_4
LZS2_k127_7963018_2	5482.XP_002549593.1	9.261e-09	69.0	KOG0946@1|root,KOG0946@2759|Eukaryota,38E2Z@33154|Opisthokonta,3NV2H@4751|Fungi,3QNJF@4890|Ascomycota,3RT0R@4891|Saccharomycetes,47C2N@766764|Debaryomycetaceae	4751|Fungi	U	Uso1 / p115 like vesicle tethering protein, C terminal region	USO1	GO:0000139,GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0005795,GO:0005798,GO:0006810,GO:0006886,GO:0006888,GO:0006906,GO:0006996,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0012505,GO:0012506,GO:0012507,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0016050,GO:0016192,GO:0022406,GO:0022607,GO:0030133,GO:0030134,GO:0030135,GO:0030658,GO:0030659,GO:0030660,GO:0030662,GO:0031090,GO:0031224,GO:0031410,GO:0031982,GO:0031984,GO:0032991,GO:0033036,GO:0034613,GO:0034622,GO:0035493,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045056,GO:0045184,GO:0046907,GO:0048193,GO:0048211,GO:0048278,GO:0048284,GO:0051179,GO:0051234,GO:0051640,GO:0051641,GO:0051649,GO:0061024,GO:0061025,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0090174,GO:0097708,GO:0098588,GO:0098791,GO:0098805,GO:0140056	2.1.1.319	ko:K11436,ko:K20361	-	-	R11216,R11217,R11219	RC00003,RC02120,RC03388,RC03390	ko00000,ko01000,ko03036,ko04131	-	-	-	Uso1_p115_C,Uso1_p115_head
LZS2_k127_7963018_1	243231.GSU0193	2.169e-135	441.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,42MU3@68525|delta/epsilon subdivisions,2WKTF@28221|Deltaproteobacteria,43SSU@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS2_k127_7963018_0	661478.OP10G_3562	2.125e-238	758.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
LZS2_k127_7963855_1	330214.NIDE4386	3.438e-109	378.0	COG1009@1|root,COG1009@2|Bacteria,3J0AN@40117|Nitrospirae	40117|Nitrospirae	CP	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00341,ko:K05577	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
LZS2_k127_7963855_2	330214.NIDE4387	1.665e-45	187.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS2_k127_7963855_0	330214.NIDE4388	5.898e-255	813.0	COG3002@1|root,COG3002@2|Bacteria,3J0VY@40117|Nitrospirae	40117|Nitrospirae	S	Uncharacterized protein conserved in bacteria (DUF2309)	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
LZS2_k127_7966994_0	756067.MicvaDRAFT_2430	5.307e-06	59.0	COG0457@1|root,COG1215@1|root,COG1216@1|root,COG0457@2|Bacteria,COG1215@2|Bacteria,COG1216@2|Bacteria,1GQBE@1117|Cyanobacteria,1H7DT@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,RgpF,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
LZS2_k127_7970990_3	388467.A19Y_3680	7.67e-07	61.0	COG2755@1|root,COG2755@2|Bacteria,1FZYY@1117|Cyanobacteria,1H9GA@1150|Oscillatoriales	1117|Cyanobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1574
LZS2_k127_7970990_1	706587.Desti_0149	6.311e-92	310.0	COG3959@1|root,COG3959@2|Bacteria,1QZY7@1224|Proteobacteria	1224|Proteobacteria	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
LZS2_k127_7970990_0	706587.Desti_0148	4.109e-95	321.0	COG3958@1|root,COG3958@2|Bacteria,1QVX3@1224|Proteobacteria,43D1R@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS2_k127_7970990_2	706587.Desti_0147	3.067e-56	202.0	COG0463@1|root,COG0463@2|Bacteria,1QW1Z@1224|Proteobacteria	1224|Proteobacteria	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_797324_0	1329516.JPST01000008_gene1970	1.394e-86	304.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli,27BN5@186824|Thermoactinomycetaceae	91061|Bacilli	E	Argininosuccinate lyase C-terminal	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
LZS2_k127_797324_1	643648.Slip_1953	3.694e-47	174.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,42K9R@68298|Syntrophomonadaceae	186801|Clostridia	M	transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS2_k127_797780_2	760192.Halhy_4409	3.281e-11	69.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes,1IVXI@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG4995 conserved	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_797780_0	443143.GM18_0083	5.7e-86	296.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNUR@28221|Deltaproteobacteria,43TZW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS2_k127_797780_1	1210884.HG799464_gene10849	1.419e-23	108.0	COG4319@1|root,COG4319@2|Bacteria,2J3B0@203682|Planctomycetes	203682|Planctomycetes	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
LZS2_k127_7978673_0	321327.CYA_1749	5.419e-308	965.0	COG0458@1|root,COG0458@2|Bacteria,1G00J@1117|Cyanobacteria,1GYRQ@1129|Synechococcus	1117|Cyanobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
LZS2_k127_7987095_5	1042156.CXIVA_19210	9.83e-07	56.0	2ETU7@1|root,33MBI@2|Bacteria,1VKRI@1239|Firmicutes,24SR1@186801|Clostridia,36SQY@31979|Clostridiaceae	186801|Clostridia	S	rRNA small subunit methyltransferase G	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS2_k127_7987095_4	1078085.HMPREF1210_00652	2.297e-09	63.0	COG3212@1|root,COG3212@2|Bacteria,1VEU1@1239|Firmicutes,4HPJK@91061|Bacilli,26G7V@186818|Planococcaceae	91061|Bacilli	S	Peptidase propeptide and YPEB domain	ykoJ	-	-	-	-	-	-	-	-	-	-	-	PepSY
LZS2_k127_7987095_0	405948.SACE_3453	5.005e-140	456.0	COG1073@1|root,COG1073@2|Bacteria,2I2SR@201174|Actinobacteria,4DYAN@85010|Pseudonocardiales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_7987095_3	316274.Haur_2857	3.239e-26	123.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
LZS2_k127_7987095_2	247490.KSU1_B0373	4.5e-42	165.0	COG2071@1|root,COG2071@2|Bacteria,2IYT5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
LZS2_k127_7987095_1	1232410.KI421428_gene1018	6.437e-110	361.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,42N2E@68525|delta/epsilon subdivisions,2WJFV@28221|Deltaproteobacteria,43TF3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF4339
LZS2_k127_8003317_0	485913.Krac_4150	1.517e-18	97.0	COG0738@1|root,COG0738@2|Bacteria,2G70U@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_8018916_1	398525.KB900701_gene1143	1.049e-08	66.0	2EBAQ@1|root,30TPG@2|Bacteria,1MXDU@1224|Proteobacteria,2U4SN@28211|Alphaproteobacteria,3JWVI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
LZS2_k127_8018916_0	1333523.L593_06205	2.556e-183	594.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria	183963|Halobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2,Usp
LZS2_k127_8029893_1	941824.TCEL_00702	7.116e-117	381.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,36DD0@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
LZS2_k127_8029893_0	489825.LYNGBM3L_63210	2.397e-145	473.0	COG0126@1|root,COG0126@2|Bacteria,1G2FM@1117|Cyanobacteria,1H76C@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
LZS2_k127_8029893_3	1159870.KB907784_gene1755	9.243e-09	67.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2VJNV@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_8029893_2	1459636.NTE_03261	4.601e-31	126.0	COG1230@1|root,arCOG01477@2157|Archaea	2157|Archaea	P	cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
LZS2_k127_8030916_4	1040983.AXAE01000018_gene5937	1.187e-24	112.0	COG4195@1|root,COG4195@2|Bacteria,1MZZB@1224|Proteobacteria,2UBK6@28211|Alphaproteobacteria,43Q35@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Poly-gamma-glutamate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Gamma_PGA_hydro
LZS2_k127_8030916_1	388467.A19Y_2447	2.293e-102	345.0	COG0075@1|root,COG0075@2|Bacteria,1G123@1117|Cyanobacteria,1H7NW@1150|Oscillatoriales	1117|Cyanobacteria	E	Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	dhsS	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	iJN678.sll1559	Aminotran_5
LZS2_k127_8030916_5	1169161.KB897735_gene5199	7.976e-05	50.0	2CCCR@1|root,2ZV30@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8030916_0	1120973.AQXL01000131_gene2039	8.219e-124	407.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,27949@186823|Alicyclobacillaceae	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_8030916_3	391038.Bphy_0378	2.285e-40	156.0	COG0500@1|root,COG0500@2|Bacteria,1RDVS@1224|Proteobacteria,2VRXQ@28216|Betaproteobacteria,1K4ED@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Thiopurine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
LZS2_k127_8030916_2	714943.Mucpa_1214	2.192e-46	177.0	COG0500@1|root,COG0500@2|Bacteria,4PNWF@976|Bacteroidetes,1J0UB@117747|Sphingobacteriia	976|Bacteroidetes	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_8033540_0	1198114.AciX9_2374	1.195e-118	390.0	COG2256@1|root,COG2256@2|Bacteria,3Y3F7@57723|Acidobacteria,2JIAH@204432|Acidobacteriia	204432|Acidobacteriia	L	AAA ATPase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
LZS2_k127_8036295_0	309798.COPRO5265_0230	1.594e-08	59.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,42F61@68295|Thermoanaerobacterales	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1,4.3.1.29	ko:K01042,ko:K17468	ko00030,ko00450,ko00970,ko01120,map00030,map00450,map00970,map01120	-	R08219,R10408	RC00544,RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
LZS2_k127_8044728_2	118168.MC7420_3254	2.182e-14	79.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HASA@1150|Oscillatoriales	1117|Cyanobacteria	S	KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	SLH,WG_beta_rep
LZS2_k127_8044728_1	1485543.JMME01000005_gene1019	1.232e-18	89.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H4QP@909932|Negativicutes	909932|Negativicutes	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
LZS2_k127_8044728_0	314230.DSM3645_16675	1.364e-40	152.0	COG3781@1|root,COG3781@2|Bacteria,2IZBM@203682|Planctomycetes	203682|Planctomycetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
LZS2_k127_8049396_2	1137281.D778_00656	0.0001053	53.0	COG3595@1|root,COG3595@2|Bacteria,4NIA2@976|Bacteroidetes,1I0CY@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
LZS2_k127_8049396_0	720554.Clocl_0743	0.0	1035.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,1TPCI@1239|Firmicutes,24BBR@186801|Clostridia,3WI0V@541000|Ruminococcaceae	186801|Clostridia	T	PNKP adenylyltransferase domain, ligase domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
LZS2_k127_8049396_1	720554.Clocl_0742	1.864e-63	222.0	COG2227@1|root,COG2227@2|Bacteria,1TQPM@1239|Firmicutes,24B8F@186801|Clostridia,3WGIM@541000|Ruminococcaceae	186801|Clostridia	H	RNA repair, ligase-Pnkp-associating, region of Hen1	-	-	-	-	-	-	-	-	-	-	-	-	Hen1_L,Methyltransf_12
LZS2_k127_8053397_1	247490.KSU1_D0609	1.34e-14	76.0	COG0425@1|root,COG0425@2|Bacteria,2J3XY@203682|Planctomycetes	203682|Planctomycetes	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
LZS2_k127_8053397_2	759914.BP951000_1446	1.033e-07	63.0	COG0457@1|root,COG0457@2|Bacteria	759914.BP951000_1446|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8053397_0	1499684.CCNP01000023_gene3346	1.018e-34	137.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,36DQI@31979|Clostridiaceae	186801|Clostridia	E	Aspartate ammonia-lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS2_k127_8058941_0	497964.CfE428DRAFT_3794	3.832e-67	248.0	COG4251@1|root,COG4251@2|Bacteria,46UHX@74201|Verrucomicrobia	74201|Verrucomicrobia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
LZS2_k127_8060298_1	639030.JHVA01000001_gene3811	1.448e-106	354.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria,2JII1@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
LZS2_k127_8060298_0	1278073.MYSTI_00935	1.614e-172	550.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,42YAM@68525|delta/epsilon subdivisions,2WUNV@28221|Deltaproteobacteria,2YV4X@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
LZS2_k127_8066863_2	1123508.JH636440_gene2136	6.829e-95	325.0	COG1696@1|root,COG1696@2|Bacteria,2IX06@203682|Planctomycetes	203682|Planctomycetes	M	membrane protein involved in D-alanine	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
LZS2_k127_8066863_0	1384057.CD33_06390	8.526e-134	434.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,4IQQV@91061|Bacilli,3IXJJ@400634|Lysinibacillus	91061|Bacilli	N	Flagellin modification protein FlmA	pseB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
LZS2_k127_8066863_1	646529.Desaci_3843	2.082e-129	425.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,263GZ@186807|Peptococcaceae	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_8071384_0	1166018.FAES_4120	1.066e-46	172.0	COG3781@1|root,COG3781@2|Bacteria,4NGJ0@976|Bacteroidetes,47M3V@768503|Cytophagia	976|Bacteroidetes	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
LZS2_k127_8071384_2	1267005.KB911255_gene2383	1.774e-13	77.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1QYI0@1224|Proteobacteria,2U6BF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	IrrE N-terminal-like domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
LZS2_k127_8071384_1	497965.Cyan7822_0005	4.406e-28	118.0	2DW4I@1|root,32V0S@2|Bacteria,1G7NI@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8071384_3	103690.17132972	0.000172	49.0	COG0457@1|root,COG0457@2|Bacteria,1G0N0@1117|Cyanobacteria,1HQK0@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
LZS2_k127_8073237_1	880073.Calab_3002	1.916e-145	469.0	COG0409@1|root,COG0409@2|Bacteria,2NP3I@2323|unclassified Bacteria	2|Bacteria	O	Hydrogenase formation hypA family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
LZS2_k127_8073237_0	383372.Rcas_3773	7.392e-156	503.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi,376DI@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
LZS2_k127_8073237_2	682795.AciX8_4210	3.797e-22	97.0	COG0298@1|root,COG0298@2|Bacteria,3Y5NM@57723|Acidobacteria,2JK31@204432|Acidobacteriia	204432|Acidobacteriia	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
LZS2_k127_8076351_1	1121422.AUMW01000019_gene1815	1.018e-11	74.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1UI8N@1239|Firmicutes,25EE0@186801|Clostridia,260HY@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF
LZS2_k127_8076351_0	338966.Ppro_3037	9.371e-268	842.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,43T0F@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
LZS2_k127_808463_1	509635.N824_12300	3.406e-13	78.0	COG0775@1|root,COG0775@2|Bacteria,4NPA7@976|Bacteroidetes,1ISHD@117747|Sphingobacteriia	976|Bacteroidetes	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS2_k127_808463_0	1382356.JQMP01000001_gene774	6.588e-50	186.0	COG0745@1|root,COG0745@2|Bacteria,2GABY@200795|Chloroflexi,27Z4B@189775|Thermomicrobia	189775|Thermomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_808463_2	102125.Xen7305DRAFT_00017990	5.462e-12	75.0	COG0642@1|root,COG2205@2|Bacteria,1GPYX@1117|Cyanobacteria,3VIT1@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11520	ko02020,map02020	M00465	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
LZS2_k127_8091777_0	1229205.BUPH_01782	1.594e-05	58.0	COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,2VP1D@28216|Betaproteobacteria,1K0YX@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM General secretory system II protein E domain protein	nfrB	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_trans_2_3,T2SSE_N
LZS2_k127_8096226_0	368407.Memar_1498	8.982e-67	253.0	COG0210@1|root,arCOG00802@2157|Archaea	2157|Archaea	L	UvrD REP helicase	-	-	3.6.4.12	ko:K03657,ko:K16898	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS2_k127_8097519_0	1158345.JNLL01000001_gene98	1.309e-45	179.0	COG0499@1|root,COG0499@2|Bacteria,2G3TI@200783|Aquificae	200783|Aquificae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS2_k127_8097519_1	941824.TCEL_00174	6.971e-30	122.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,36IU5@31979|Clostridiaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
LZS2_k127_8097812_1	1449353.JQMQ01000005_gene1235	2.662e-06	57.0	COG3170@1|root,COG3170@2|Bacteria,2H8D5@201174|Actinobacteria	201174|Actinobacteria	NU	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8104468_0	5888.CAK78268	2.609e-12	78.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZD5C@5878|Ciliophora	5878|Ciliophora	GOT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
LZS2_k127_8115962_0	485913.Krac_4391	6.36e-80	274.0	COG4221@1|root,COG4221@2|Bacteria,2G8WF@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_8115962_1	1124780.ANNU01000078_gene771	8.277e-28	117.0	COG1225@1|root,COG1225@2|Bacteria,4P4YA@976|Bacteroidetes	976|Bacteroidetes	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_8131306_1	1220583.GOACH_15_00470	3.633e-53	212.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4GARS@85026|Gordoniaceae	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_8131306_0	378806.STAUR_3417	4.261e-55	206.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4346X@68525|delta/epsilon subdivisions,2XA3R@28221|Deltaproteobacteria,2YXWE@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TonB_C
LZS2_k127_8131306_2	1216362.B437_04790	7.538e-07	61.0	28JBJ@1|root,2Z968@2|Bacteria,37BQ9@32066|Fusobacteria	32066|Fusobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8141381_1	596151.DesfrDRAFT_2486	3.163e-24	110.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42U59@68525|delta/epsilon subdivisions,2WRMP@28221|Deltaproteobacteria,2M8XT@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM amino acid permease-associated region	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
LZS2_k127_8141381_0	1124780.ANNU01000016_gene1858	8.418e-180	590.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,47KYI@768503|Cytophagia	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS2_k127_8142001_0	1242864.D187_010056	2.064e-08	58.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,43C6E@68525|delta/epsilon subdivisions,2WTIV@28221|Deltaproteobacteria,2YZ25@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_8143457_2	266779.Meso_2924	3.481e-55	206.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,43GZZ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EH	PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS2_k127_8143457_5	1408422.JHYF01000002_gene2389	1.281e-05	53.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,36DJE@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS2_k127_8143457_4	5911.EAR95020	4.306e-09	68.0	COG3914@1|root,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_8143457_3	272560.BPSS1130	8.372e-40	160.0	28M8C@1|root,2ZAMI@2|Bacteria,1R981@1224|Proteobacteria,2W6T7@28216|Betaproteobacteria,1KCKR@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8143457_1	744979.R2A130_2726	6.484e-107	353.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,2TTJC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short,adh_short_C2
LZS2_k127_8143457_0	330214.NIDE4254	1.787e-151	491.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_8148077_0	1232410.KI421418_gene2172	1.57e-91	318.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,42ND1@68525|delta/epsilon subdivisions,2X753@28221|Deltaproteobacteria,43VYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_8148077_1	28229.ND2E_1592	7.238e-07	51.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,2Q5WY@267889|Colwelliaceae	1236|Gammaproteobacteria	T	PFAM response regulator receiver, transcriptional regulator domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_8148185_1	32057.KB217478_gene1576	1.519e-09	62.0	COG3153@1|root,COG3153@2|Bacteria,1GQ2E@1117|Cyanobacteria	1117|Cyanobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8148185_0	861299.J421_1812	1.95e-78	284.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
LZS2_k127_8149298_1	579137.Metvu_0042	0.0002144	53.0	COG0501@1|root,arCOG01334@2157|Archaea	2157|Archaea	O	Zn-dependent protease with chaperone function	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48
LZS2_k127_8149298_0	530564.Psta_0557	2.132e-06	59.0	COG4782@1|root,COG5602@1|root,COG4782@2|Bacteria,COG5602@2|Bacteria,2IWWR@203682|Planctomycetes	203682|Planctomycetes	B	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
LZS2_k127_8150270_1	321327.CYA_1705	2.58e-35	138.0	COG0607@1|root,COG0607@2|Bacteria,1GPXG@1117|Cyanobacteria,1H0XW@1129|Synechococcus	1117|Cyanobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS2_k127_8150270_0	485913.Krac_3644	3.326e-37	151.0	COG0179@1|root,COG0179@2|Bacteria,2G7MW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
LZS2_k127_8159032_0	926567.TheveDRAFT_1802	1.626e-160	515.0	COG0369@1|root,COG1151@2|Bacteria,3TA79@508458|Synergistetes	508458|Synergistetes	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
LZS2_k127_8159032_1	927677.ALVU02000001_gene4341	5.542e-09	65.0	COG0025@1|root,COG0025@2|Bacteria,1G1D4@1117|Cyanobacteria,1H4UM@1142|Synechocystis	1117|Cyanobacteria	U	Sodium/hydrogen exchanger family	nhaS2	GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042592,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098719,GO:0098739,GO:0098771,GO:0099516,GO:0099587,GO:1902600	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
LZS2_k127_8159099_0	682795.AciX8_1219	2.679e-135	438.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria,2JIAW@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS2_k127_8167617_2	517417.Cpar_0559	1.659e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1FDVB@1090|Chlorobi	1090|Chlorobi	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_8167617_0	102232.GLO73106DRAFT_00038040	1.472e-187	595.0	COG0104@1|root,COG0104@2|Bacteria,1G147@1117|Cyanobacteria	1117|Cyanobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
LZS2_k127_8167617_1	404380.Gbem_3205	1.278e-13	78.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43UA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
LZS2_k127_8171941_0	1128427.KB904821_gene1220	2.656e-17	82.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	adiA	-	2.7.7.65,4.1.1.19	ko:K01584,ko:K20955	ko00330,ko01100,ko05111,map00330,map01100,map05111	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	GGDEF,Guanylate_cyc,HATPase_c,HisKA,OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N,PAS_4,PAS_9,Response_reg
LZS2_k127_8171941_1	1121289.JHVL01000015_gene2697	0.0002281	52.0	COG2304@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria,1V1ZB@1239|Firmicutes,24T2R@186801|Clostridia,36VFZ@31979|Clostridiaceae	186801|Clostridia	M	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
LZS2_k127_8184212_0	1123242.JH636434_gene5132	3.502e-14	72.0	COG5285@1|root,COG5285@2|Bacteria,2IZRZ@203682|Planctomycetes	203682|Planctomycetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS2_k127_8185742_0	1267533.KB906738_gene2044	8.107e-38	160.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_8185742_1	402881.Plav_3309	1.647e-26	120.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria,1JQM4@119043|Rhodobiaceae	28211|Alphaproteobacteria	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_8185742_2	419947.MRA_1512	0.0007044	46.0	COG5285@1|root,COG5285@2|Bacteria,2HSK5@201174|Actinobacteria,23CT1@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS2_k127_8197129_0	251221.35211847	1.264e-62	222.0	COG2258@1|root,COG2258@2|Bacteria,1G4BR@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
LZS2_k127_8201641_0	65093.PCC7418_3329	8.165e-146	479.0	COG1032@1|root,COG1032@2|Bacteria,1G187@1117|Cyanobacteria	1117|Cyanobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_8201641_1	383372.Rcas_2147	2.072e-44	173.0	COG1184@1|root,COG1184@2|Bacteria,2G9CC@200795|Chloroflexi,3762Q@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the eIF-2B alpha beta delta subunits family	-	-	-	ko:K03680	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	IF-2B
LZS2_k127_8202372_1	317936.Nos7107_2270	3.047e-63	227.0	COG0812@1|root,COG0812@2|Bacteria,1FZXZ@1117|Cyanobacteria,1HM51@1161|Nostocales	1117|Cyanobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
LZS2_k127_8202372_0	1379698.RBG1_1C00001G0397	4.474e-106	361.0	COG0773@1|root,COG0773@2|Bacteria,2NNPU@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the MurCDEF family	murC	GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iECP_1309.ECP_0093,iJN678.murC	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_8202546_0	1535287.JP74_09480	2.267e-104	345.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,3N65Z@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI2	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS2_k127_8202546_1	234267.Acid_4336	3.122e-94	315.0	COG4805@1|root,COG4805@2|Bacteria,3Y47D@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
LZS2_k127_8216754_1	111781.Lepto7376_2942	8.912e-27	113.0	COG1630@1|root,COG1630@2|Bacteria,1G0AG@1117|Cyanobacteria,1H7EX@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM NurA domain	-	-	-	-	-	-	-	-	-	-	-	-	NurA
LZS2_k127_8216754_0	1340493.JNIF01000003_gene1854	1.748e-78	281.0	2AHFT@1|root,317T3@2|Bacteria,3Y8T4@57723|Acidobacteria	1340493.JNIF01000003_gene1854|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8216754_2	211165.AJLN01000076_gene487	0.0004827	44.0	COG1670@1|root,COG1670@2|Bacteria,1G5HU@1117|Cyanobacteria,1JHTS@1189|Stigonemataceae	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
LZS2_k127_8217606_0	269084.syc1032_d	2.376e-11	75.0	COG0681@1|root,COG0681@2|Bacteria,1G54H@1117|Cyanobacteria,1GZ4P@1129|Synechococcus	1117|Cyanobacteria	U	Belongs to the peptidase S26 family	lepB2	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
LZS2_k127_8218750_0	555779.Dthio_PD0443	4.821e-37	148.0	2CNE3@1|root,32SGW@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF3841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3841
LZS2_k127_8221424_2	686340.Metal_2426	2.268e-53	207.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RX1G@1236|Gammaproteobacteria,1XG47@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
LZS2_k127_8221424_4	696369.KI912183_gene1505	1.016e-46	179.0	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24BFG@186801|Clostridia,263S2@186807|Peptococcaceae	186801|Clostridia	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
LZS2_k127_8221424_1	696369.KI912183_gene1504	1.014e-70	259.0	COG2801@1|root,COG2801@2|Bacteria,1TQH6@1239|Firmicutes,249ZV@186801|Clostridia,2637H@186807|Peptococcaceae	186801|Clostridia	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,Mu-transpos_C,rve
LZS2_k127_8221424_5	868595.Desca_2296	5.265e-06	57.0	COG3677@1|root,COG3677@2|Bacteria,1VHIN@1239|Firmicutes,24SRT@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8221424_0	686340.Metal_2426	6.898e-187	640.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RX1G@1236|Gammaproteobacteria,1XG47@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
LZS2_k127_8221424_3	1121381.JNIV01000193_gene2715	5.161e-48	176.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
LZS2_k127_8224963_3	596152.DesU5LDRAFT_3730	9.13e-55	195.0	COG4803@1|root,COG4803@2|Bacteria,1RAJ2@1224|Proteobacteria,42RBR@68525|delta/epsilon subdivisions,2WN5K@28221|Deltaproteobacteria,2MAEW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
LZS2_k127_8224963_2	666681.M301_1118	8.977e-101	342.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,2KM5U@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
LZS2_k127_8224963_1	1382359.JIAL01000001_gene129	2.287e-187	600.0	COG0488@1|root,COG0488@2|Bacteria,3Y3IA@57723|Acidobacteria,2JI1Y@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
LZS2_k127_8224963_0	378806.STAUR_2075	3.077e-263	828.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2X6WF@28221|Deltaproteobacteria,2YWNJ@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
LZS2_k127_8225565_0	1140.Synpcc7942_1141	3.87e-23	104.0	COG3793@1|root,COG3793@2|Bacteria,1G090@1117|Cyanobacteria,1H06D@1129|Synechococcus	1117|Cyanobacteria	P	Tellurite resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Mo-nitro_C,TerB
LZS2_k127_8226819_1	1460635.JCM19038_1726	2.342e-81	284.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HC4S@91061|Bacilli	91061|Bacilli	C	carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS2_k127_8226819_0	1313172.YM304_11100	4.61e-155	521.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,4CMSA@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family M1 domain	-	-	-	ko:K08776	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
LZS2_k127_8234660_3	316274.Haur_4532	1.198e-47	186.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G7M2@200795|Chloroflexi,377Z3@32061|Chloroflexia	32061|Chloroflexia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS2_k127_8234660_2	1245469.S58_43880	1.564e-50	189.0	COG2173@1|root,COG2173@2|Bacteria,1RBFI@1224|Proteobacteria,2UHKM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	D-ala-D-ala dipeptidase	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
LZS2_k127_8234660_1	1173020.Cha6605_3786	4.763e-66	234.0	COG2267@1|root,COG2267@2|Bacteria,1G14K@1117|Cyanobacteria	1117|Cyanobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_8234660_0	1173020.Cha6605_3787	1.442e-145	480.0	COG0770@1|root,COG0770@2|Bacteria,1G1G4@1117|Cyanobacteria	1117|Cyanobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_8237931_0	258052.JNYV01000002_gene1261	4.3e-57	215.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,2M17I@2063|Kitasatospora	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_8238484_2	649349.Lbys_1537	5.612e-08	65.0	COG0793@1|root,COG0793@2|Bacteria,4NEF4@976|Bacteroidetes,47K87@768503|Cytophagia	976|Bacteroidetes	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ,PDZ_2
LZS2_k127_8238484_0	1303518.CCALI_00309	1.527e-31	132.0	COG2365@1|root,COG2365@2|Bacteria	2|Bacteria	T	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	DSPc,DUF442,PTPlike_phytase,Y_phosphatase2,Y_phosphatase3
LZS2_k127_8238484_1	765420.OSCT_2500	2.01e-31	131.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_8241499_0	526227.Mesil_0202	3.043e-93	313.0	COG0458@1|root,COG0458@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
LZS2_k127_8241499_1	340099.Teth39_1313	3.591e-63	236.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_8241964_0	456320.Mvol_0316	9.264e-09	68.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,23R54@183939|Methanococci	183939|Methanococci	S	SMART Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
LZS2_k127_8244904_0	517418.Ctha_0233	9.391e-124	419.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1FDRS@1090|Chlorobi	1090|Chlorobi	C	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
LZS2_k127_8244904_1	517418.Ctha_2508	1.208e-22	103.0	COG3118@1|root,COG3118@2|Bacteria,1FE4C@1090|Chlorobi	1090|Chlorobi	O	Belongs to the thioredoxin family	-	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
LZS2_k127_8244904_2	1313301.AUGC01000005_gene216	3.205e-06	56.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,4NKPZ@976|Bacteroidetes	976|Bacteroidetes	S	Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12
LZS2_k127_8261375_0	1487953.JMKF01000065_gene4609	5.031e-96	331.0	COG0768@1|root,COG0768@2|Bacteria,1G03W@1117|Cyanobacteria,1H7NT@1150|Oscillatoriales	1117|Cyanobacteria	M	Penicillin-binding protein, dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
LZS2_k127_8283266_0	911045.PSE_0394	1.214e-145	475.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	polyphosphate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
LZS2_k127_8283266_1	1484460.JSWG01000012_gene1393	1.377e-18	86.0	2DNXG@1|root,32ZNF@2|Bacteria,4NV9Z@976|Bacteroidetes,1I563@117743|Flavobacteriia	976|Bacteroidetes	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
LZS2_k127_8283266_2	243090.RB12718	4.96e-17	87.0	COG1418@1|root,COG1418@2|Bacteria,2IXYI@203682|Planctomycetes	203682|Planctomycetes	S	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
LZS2_k127_8286175_0	121759.XP_010757512.1	8.842e-16	90.0	2CD6R@1|root,2SRD6@2759|Eukaryota,3ANVJ@33154|Opisthokonta,3PESX@4751|Fungi,3R2R9@4890|Ascomycota,20GG4@147545|Eurotiomycetes,3B01H@33183|Onygenales,3FRYI@34383|Onygenales incertae sedis	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8290333_1	760568.Desku_1733	9.934e-172	558.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,26076@186807|Peptococcaceae	186801|Clostridia	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_syn_2C,Polysacc_synt_2
LZS2_k127_8290333_0	935948.KE386494_gene340	1.457e-289	911.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
LZS2_k127_8297121_0	1242864.D187_006042	2.256e-33	136.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase,TonB_C
LZS2_k127_8304034_0	13035.Dacsa_0144	1.37e-49	193.0	COG4399@1|root,COG4399@2|Bacteria,1G037@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the UPF0754 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
LZS2_k127_8304034_1	1033734.CAET01000069_gene2404	1.943e-14	84.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_8304034_2	316067.Geob_0902	1.632e-12	77.0	COG0457@1|root,COG0457@2|Bacteria,1PEPM@1224|Proteobacteria,42Y8V@68525|delta/epsilon subdivisions,2WU79@28221|Deltaproteobacteria,43TE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8
LZS2_k127_830889_0	56110.Oscil6304_1113	1.85e-17	90.0	2DW4I@1|root,32V0S@2|Bacteria,1GA2R@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8310983_0	765420.OSCT_2677	4.229e-33	143.0	COG0515@1|root,COG0515@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_8310983_1	591019.Shell_0483	0.0002709	53.0	COG0515@1|root,arCOG03682@2157|Archaea,2XQUK@28889|Crenarchaeota	28889|Crenarchaeota	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_8319008_0	1229172.JQFA01000004_gene1397	4.971e-33	133.0	COG3854@1|root,COG3854@2|Bacteria,1G0U1@1117|Cyanobacteria,1H78Y@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	ycf45	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
LZS2_k127_8349995_0	1415778.JQMM01000001_gene958	0.0	1066.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,1RNA5@1236|Gammaproteobacteria,1J5DB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
LZS2_k127_8349995_2	251221.35211376	2.934e-29	136.0	COG5002@1|root,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS2_k127_8349995_1	306281.AJLK01000189_gene1805	7.494e-52	209.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
LZS2_k127_8355076_0	1121403.AUCV01000068_gene2206	3.428e-33	141.0	COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,42QIQ@68525|delta/epsilon subdivisions,2WM7F@28221|Deltaproteobacteria,2MJ1M@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS2_k127_8355076_1	395493.BegalDRAFT_2529	9.275e-14	83.0	COG0501@1|root,COG0501@2|Bacteria,1NA37@1224|Proteobacteria,1RY3D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS2_k127_836870_3	1123075.AUDP01000004_gene739	0.0003585	53.0	COG1198@1|root,COG4260@1|root,COG1198@2|Bacteria,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3WGMI@541000|Ruminococcaceae	186801|Clostridia	L	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zinc_ribbon_2
LZS2_k127_836870_2	1313421.JHBV01000008_gene4356	2.844e-25	113.0	COG2110@1|root,COG2110@2|Bacteria,4NTFW@976|Bacteroidetes	976|Bacteroidetes	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
LZS2_k127_836870_1	1358423.N180_15590	6.47e-34	136.0	COG1297@1|root,COG1297@2|Bacteria,4NEIY@976|Bacteroidetes,1IP8J@117747|Sphingobacteriia	976|Bacteroidetes	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
LZS2_k127_836870_0	497964.CfE428DRAFT_0450	6.922e-68	262.0	COG0515@1|root,COG0515@2|Bacteria,46W45@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8383220_0	102129.Lepto7375DRAFT_0471	9.236e-33	140.0	2F66C@1|root,33YQF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8400977_3	485913.Krac_8960	6.836e-20	92.0	COG0500@1|root,COG2226@2|Bacteria,2G6R0@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_8400977_0	696369.KI912183_gene1737	2.038e-83	290.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,260IB@186807|Peptococcaceae	186801|Clostridia	O	PDZ domain (Also known as DHR or GLGF)	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_8400977_2	879212.DespoDRAFT_00427	1.739e-43	170.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2WKQV@28221|Deltaproteobacteria,2MN3Y@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
LZS2_k127_8400977_1	1123326.JFBL01000006_gene1037	8.016e-75	264.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2YQUV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
LZS2_k127_8406777_0	485913.Krac_7305	2.318e-19	99.0	COG3509@1|root,COG3509@2|Bacteria,2G91Y@200795|Chloroflexi	2|Bacteria	Q	Esterase PHB depolymerase	estB	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase,Esterase_phd
LZS2_k127_8406777_1	1122223.KB890687_gene2915	5.062e-07	57.0	COG1413@1|root,COG5330@1|root,COG1413@2|Bacteria,COG5330@2|Bacteria,1WMZN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Leucine rich repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_8408582_0	555079.Toce_1087	1.14e-66	240.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,42G77@68295|Thermoanaerobacterales	186801|Clostridia	D	tyrosine recombinase XerC	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS2_k127_8408582_1	1173264.KI913949_gene4010	9.415e-08	61.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H7GW@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,CHAT,TPR_12,TPR_7,TPR_8
LZS2_k127_8409618_0	1122182.KB903816_gene1610	7.817e-85	301.0	COG0436@1|root,COG2890@1|root,COG0436@2|Bacteria,COG2890@2|Bacteria,2GX61@201174|Actinobacteria	201174|Actinobacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8409618_1	39416.CAZ83937	0.0004646	47.0	COG0457@1|root,KOG1840@2759|Eukaryota,38C2F@33154|Opisthokonta,3NYVZ@4751|Fungi,3QJJI@4890|Ascomycota	4751|Fungi	Z	domain) protein	-	-	-	-	-	-	-	-	-	-	-	-	HET,NB-ARC,PNP_UDP_1,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_8421877_0	536227.CcarbDRAFT_3677	5.681e-87	297.0	2BVU5@1|root,2Z9FH@2|Bacteria,1TSH1@1239|Firmicutes,247VS@186801|Clostridia,36E2V@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8421877_1	332101.JIBU02000014_gene2489	9.288e-81	282.0	COG0104@1|root,COG0104@2|Bacteria,1TQBR@1239|Firmicutes,24EJZ@186801|Clostridia,36G9Q@31979|Clostridiaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	-	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
LZS2_k127_8431465_0	324602.Caur_0620	8.291e-88	301.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,376AC@32061|Chloroflexia	32061|Chloroflexia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
LZS2_k127_8432052_0	313612.L8106_04726	3e-153	492.0	COG1902@1|root,COG1902@2|Bacteria,1FZYT@1117|Cyanobacteria,1H861@1150|Oscillatoriales	1117|Cyanobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
LZS2_k127_8432052_2	522772.Dacet_2039	4.03e-65	229.0	COG2070@1|root,COG2070@2|Bacteria,2GF1U@200930|Deferribacteres	200930|Deferribacteres	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
LZS2_k127_8432052_1	472759.Nhal_2109	2.891e-80	273.0	COG0428@1|root,COG0428@2|Bacteria,1PMN6@1224|Proteobacteria,1SIQH@1236|Gammaproteobacteria,1X1XX@135613|Chromatiales	135613|Chromatiales	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
LZS2_k127_8432052_3	102125.Xen7305DRAFT_00053870	7.973e-08	53.0	COG3328@1|root,COG3328@2|Bacteria,1GFB1@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
LZS2_k127_8433770_3	1235835.C814_03325	5.086e-08	61.0	COG0835@1|root,COG0835@2|Bacteria,1V431@1239|Firmicutes,24HHD@186801|Clostridia,3WJ7S@541000|Ruminococcaceae	186801|Clostridia	NT	Chemotaxis signal transduction protein	cheW1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS2_k127_8433770_4	1121937.AUHJ01000001_gene784	7.309e-08	63.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RYHN@1236|Gammaproteobacteria,467HD@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
LZS2_k127_8433770_2	1009370.ALO_15772	6.109e-10	71.0	COG1463@1|root,COG1463@2|Bacteria,1UI1N@1239|Firmicutes,4H3F6@909932|Negativicutes	909932|Negativicutes	Q	Virulence factor Mce family protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
LZS2_k127_8433770_0	1101188.KI912155_gene2182	1.055e-128	445.0	COG0642@1|root,COG0642@2|Bacteria,2I58H@201174|Actinobacteria	201174|Actinobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
LZS2_k127_8433770_1	382464.ABSI01000010_gene3362	1.721e-25	121.0	COG2197@1|root,COG2197@2|Bacteria,46V6C@74201|Verrucomicrobia,2IUHI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_8434070_0	880073.Calab_2945	2.137e-165	535.0	COG0145@1|root,COG0145@2|Bacteria,2NP17@2323|unclassified Bacteria	2|Bacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
LZS2_k127_8434070_1	945713.IALB_1014	1.862e-95	329.0	COG2851@1|root,COG2851@2|Bacteria	2|Bacteria	C	citrate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8434070_2	1120963.KB894515_gene340	3.347e-65	231.0	COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,1S5FF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_8435731_0	211165.AJLN01000061_gene3953	9.059e-47	188.0	COG0860@1|root,COG0860@2|Bacteria,1G08T@1117|Cyanobacteria,1JH3H@1189|Stigonemataceae	1117|Cyanobacteria	M	Bacterial SH3 domain homologues	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_4
LZS2_k127_8435731_2	945713.IALB_1974	4.707e-15	85.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
LZS2_k127_8435731_1	380703.AHA_3763	2.114e-24	106.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1Y3S7@135624|Aeromonadales	135624|Aeromonadales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
LZS2_k127_8451106_0	1242864.D187_006042	1.385e-59	230.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase,TonB_C
LZS2_k127_8451106_1	1207063.P24_06681	1.03e-15	80.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2TS1E@28211|Alphaproteobacteria,2JQ0T@204441|Rhodospirillales	204441|Rhodospirillales	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
LZS2_k127_8455539_0	1536773.R70331_14700	4.636e-66	241.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4309,Glyco_hydro_3
LZS2_k127_8455539_1	402777.KB235898_gene5022	1.05e-46	181.0	COG3409@1|root,COG3757@1|root,COG3409@2|Bacteria,COG3757@2|Bacteria,1G3TT@1117|Cyanobacteria,1H8M4@1150|Oscillatoriales	1117|Cyanobacteria	M	SMART Glycoside hydrolase, family 25 subgroup	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,PG_binding_1
LZS2_k127_8455928_0	1341151.ASZU01000004_gene438	3.643e-52	202.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27B40@186824|Thermoactinomycetaceae	91061|Bacilli	KLT	Protein tyrosine kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_8455928_1	30611.ENSOGAP00000014321	9.893e-06	50.0	KOG1947@1|root,KOG1947@2759|Eukaryota,39IST@33154|Opisthokonta,3BAH5@33208|Metazoa,3CS27@33213|Bilateria,482SV@7711|Chordata,48XHR@7742|Vertebrata,3J98W@40674|Mammalia,35MHR@314146|Euarchontoglires,4M8PB@9443|Primates	33208|Metazoa	S	F-box and leucine-rich repeat protein 13	FBXL13	GO:0000209,GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070647,GO:0071704,GO:0140096,GO:1901564	2.7.4.3	ko:K00939,ko:K10279	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04121,ko04147	-	-	-	F-box,F-box-like,LRR_6
LZS2_k127_8460816_1	2903.EOD22248	5.473e-16	85.0	KOG1011@1|root,KOG1011@2759|Eukaryota	2759|Eukaryota	S	diacylglycerol binding	-	-	-	ko:K15293	ko04721,map04721	-	-	-	ko00000,ko00001,ko04131	-	-	-	C2,Membr_traf_MHD
LZS2_k127_8460816_0	56110.Oscil6304_2721	9.445e-25	113.0	COG2304@1|root,COG2304@2|Bacteria,1G11R@1117|Cyanobacteria,1H7TP@1150|Oscillatoriales	2|Bacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VIT,VWA_2,VWA_3,vWA-TerF-like
LZS2_k127_8466709_0	378806.STAUR_3161	1.12e-306	968.0	COG2373@1|root,COG2373@2|Bacteria,1QTCC@1224|Proteobacteria,437VK@68525|delta/epsilon subdivisions,2X356@28221|Deltaproteobacteria,2YUBE@29|Myxococcales	28221|Deltaproteobacteria	S	A-macroglobulin complement component	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
LZS2_k127_8470865_0	696747.NIES39_L06650	3.35e-11	73.0	COG2267@1|root,COG2267@2|Bacteria,1G1J9@1117|Cyanobacteria,1H7GP@1150|Oscillatoriales	1117|Cyanobacteria	I	Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6
LZS2_k127_8474014_0	1303518.CCALI_01080	9.942e-33	136.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS2_k127_847431_0	1121468.AUBR01000066_gene910	7.207e-112	370.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,42FCG@68295|Thermoanaerobacterales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_8479667_0	251221.35214657	3.979e-110	383.0	COG0358@1|root,COG0358@2|Bacteria,1G0TV@1117|Cyanobacteria	1117|Cyanobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
LZS2_k127_8497401_1	1341646.CBMO010000024_gene5974	9.77e-05	55.0	28IHI@1|root,2Z8IR@2|Bacteria,2GWA1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8497401_0	314230.DSM3645_06419	1.685e-06	60.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,2IYFX@203682|Planctomycetes	203682|Planctomycetes	KTU	Flp pilus assembly protein, ATPase CpaE	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,Response_reg
LZS2_k127_8505853_0	251221.35213139	1.353e-222	696.0	COG0055@1|root,COG0055@2|Bacteria,1G1BK@1117|Cyanobacteria	1117|Cyanobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS2_k127_8505853_2	795359.TOPB45_0785	1.034e-31	133.0	COG0740@1|root,COG0740@2|Bacteria,2GHB8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS2_k127_8505853_3	871963.Desdi_3437	8.366e-26	111.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,2629N@186807|Peptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
LZS2_k127_8505853_1	448385.sce4952	3.927e-52	205.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria,2YUVI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_8528413_2	335659.S23_11620	1.217e-07	57.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,2TSWJ@28211|Alphaproteobacteria,3JX1W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
LZS2_k127_8528413_1	452637.Oter_0554	8.842e-136	446.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
LZS2_k127_8528413_0	1124780.ANNU01000024_gene3046	1.991e-206	657.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	paaN	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS2_k127_8530703_4	1128421.JAGA01000003_gene3106	2.544e-07	57.0	COG0457@1|root,COG0457@2|Bacteria	1128421.JAGA01000003_gene3106|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8530703_0	562970.Btus_1426	1.807e-51	208.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_8530703_2	530564.Psta_0571	5.125e-23	102.0	2E7HP@1|root,33206@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1475)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1475
LZS2_k127_8530703_3	1278078.G419_07564	2.489e-07	60.0	COG3427@1|root,COG3427@2|Bacteria,2I2PW@201174|Actinobacteria,4G9EP@85025|Nocardiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
LZS2_k127_8530703_1	1323663.AROI01000002_gene1227	1.526e-45	171.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
LZS2_k127_8534144_0	240016.ABIZ01000001_gene1698	8.145e-05	53.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
LZS2_k127_8541493_2	1254432.SCE1572_25155	1.027e-45	182.0	2ABT6@1|root,3119R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8541493_1	604331.AUHY01000058_gene1341	7.712e-116	377.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB1	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0247c	Fer2_3,Fer4_8
LZS2_k127_8541493_0	351607.Acel_1865	3.302e-129	422.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,4ES69@85013|Frankiales	201174|Actinobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS2_k127_85441_0	391625.PPSIR1_24599	1.986e-10	73.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WIJ8@28221|Deltaproteobacteria,2Z2WU@29|Myxococcales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
LZS2_k127_85441_1	333138.LQ50_11860	0.0007889	49.0	COG0286@1|root,COG1002@1|root,COG0286@2|Bacteria,COG1002@2|Bacteria,1TQ39@1239|Firmicutes,4HA3J@91061|Bacilli,1ZCQ9@1386|Bacillus	91061|Bacilli	V	restriction	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,N6_Mtase
LZS2_k127_8545308_2	439235.Dalk_3428	8.733e-12	74.0	COG0457@1|root,COG0457@2|Bacteria,1N5M0@1224|Proteobacteria,42U23@68525|delta/epsilon subdivisions,2WQ2H@28221|Deltaproteobacteria,2MKG5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
LZS2_k127_8545308_1	485916.Dtox_3563	3.183e-23	112.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,24ACH@186801|Clostridia,260X8@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
LZS2_k127_8545308_0	485913.Krac_8160	2.133e-44	176.0	COG4934@1|root,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	He_PIG,Peptidase_S8,Pro-kuma_activ
LZS2_k127_8551685_1	28377.ENSACAP00000007194	5.584e-15	83.0	COG2267@1|root,KOG1455@2759|Eukaryota,38I1Q@33154|Opisthokonta,3BHGS@33208|Metazoa,3CSYE@33213|Bilateria,483MQ@7711|Chordata,48WRH@7742|Vertebrata	33208|Metazoa	I	regulation of endocannabinoid signaling pathway	MGLL	GO:0001558,GO:0001676,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005811,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006638,GO:0006639,GO:0006690,GO:0006950,GO:0006952,GO:0006954,GO:0007275,GO:0007399,GO:0008015,GO:0008150,GO:0008152,GO:0008277,GO:0008361,GO:0009056,GO:0009966,GO:0009987,GO:0010646,GO:0010648,GO:0010769,GO:0010975,GO:0012505,GO:0016020,GO:0016042,GO:0016043,GO:0016298,GO:0016787,GO:0016788,GO:0019369,GO:0019752,GO:0019898,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023057,GO:0030154,GO:0030424,GO:0030516,GO:0031344,GO:0031347,GO:0031644,GO:0031974,GO:0031981,GO:0031984,GO:0032101,GO:0032501,GO:0032502,GO:0032535,GO:0032787,GO:0033267,GO:0033559,GO:0035150,GO:0035296,GO:0036155,GO:0040008,GO:0042175,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043196,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044057,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0045202,GO:0045595,GO:0045664,GO:0046461,GO:0046464,GO:0046486,GO:0046503,GO:0046983,GO:0047372,GO:0048167,GO:0048519,GO:0048523,GO:0048583,GO:0048638,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050727,GO:0050767,GO:0050770,GO:0050789,GO:0050793,GO:0050794,GO:0050804,GO:0050805,GO:0050880,GO:0050896,GO:0051128,GO:0051239,GO:0051930,GO:0051931,GO:0051960,GO:0052689,GO:0060284,GO:0060292,GO:0061387,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0071944,GO:0080134,GO:0090066,GO:0097458,GO:0097746,GO:0097756,GO:0098827,GO:0099177,GO:0120025,GO:0120035,GO:0120038,GO:1901568,GO:1901575,GO:2000026,GO:2000124	3.1.1.23	ko:K01054	ko00561,ko01100,ko04714,ko04723,ko04923,map00561,map01100,map04714,map04723,map04923	M00098	R01351	RC00020,RC00041	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Hydrolase_4
LZS2_k127_8551685_0	1242864.D187_000641	8.481e-54	206.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
LZS2_k127_8557597_1	856793.MICA_1189	7.518e-29	125.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,4BPF3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
LZS2_k127_8557597_0	1056512.D515_01852	5.382e-62	218.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,1Y01B@135623|Vibrionales	135623|Vibrionales	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS2_k127_8566557_1	984262.SGRA_3961	1.719e-61	217.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes,1ISBJ@117747|Sphingobacteriia	976|Bacteroidetes	L	NUDIX domain	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS2_k127_8566557_0	204669.Acid345_4600	8.78e-72	255.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria,2JJG2@204432|Acidobacteriia	204432|Acidobacteriia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_8568377_6	443143.GM18_4412	4.497e-05	55.0	COG3577@1|root,COG3577@2|Bacteria,1RIR3@1224|Proteobacteria,42UXY@68525|delta/epsilon subdivisions,2WR2W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,DUF4124
LZS2_k127_8568377_3	118173.KB235914_gene3704	5.357e-24	117.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1FZWQ@1117|Cyanobacteria,1H6WA@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	GUN4,Pkinase,TPR_1,TPR_11,WD40
LZS2_k127_8568377_5	55529.EKX49630	4.361e-05	56.0	COG0639@1|root,KOG0376@2759|Eukaryota	2759|Eukaryota	T	response to arachidonic acid	PPP5C	GO:0000165,GO:0000166,GO:0000278,GO:0000302,GO:0001101,GO:0001932,GO:0001933,GO:0001965,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005819,GO:0005829,GO:0005856,GO:0005911,GO:0006139,GO:0006325,GO:0006351,GO:0006464,GO:0006468,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006913,GO:0006950,GO:0006979,GO:0006996,GO:0007049,GO:0007154,GO:0007165,GO:0008017,GO:0008092,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009410,GO:0009416,GO:0009506,GO:0009628,GO:0009636,GO:0009639,GO:0009889,GO:0009890,GO:0009892,GO:0009966,GO:0009967,GO:0009987,GO:0010017,GO:0010019,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010288,GO:0010380,GO:0010467,GO:0010563,GO:0010605,GO:0010646,GO:0010647,GO:0010941,GO:0012505,GO:0014070,GO:0014072,GO:0015630,GO:0015631,GO:0016020,GO:0016021,GO:0016043,GO:0016070,GO:0016310,GO:0016311,GO:0016569,GO:0016570,GO:0016576,GO:0016604,GO:0016607,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0017157,GO:0018130,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0022607,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0030054,GO:0030176,GO:0030425,GO:0030554,GO:0031072,GO:0031090,GO:0031224,GO:0031227,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031399,GO:0031400,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0031984,GO:0032268,GO:0032269,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032879,GO:0032991,GO:0033036,GO:0033143,GO:0033145,GO:0033365,GO:0033554,GO:0033993,GO:0034599,GO:0034613,GO:0034614,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0035639,GO:0035690,GO:0035970,GO:0036094,GO:0036211,GO:0036477,GO:0042175,GO:0042221,GO:0042325,GO:0042326,GO:0042493,GO:0042542,GO:0042578,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043204,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043278,GO:0043279,GO:0043412,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044432,GO:0044444,GO:0044446,GO:0044451,GO:0044463,GO:0044464,GO:0045920,GO:0045936,GO:0046483,GO:0046677,GO:0046686,GO:0046906,GO:0046907,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051048,GO:0051049,GO:0051051,GO:0051169,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051193,GO:0051195,GO:0051234,GO:0051246,GO:0051248,GO:0051259,GO:0051276,GO:0051291,GO:0051641,GO:0051649,GO:0051716,GO:0051879,GO:0055044,GO:0060255,GO:0060359,GO:0060548,GO:0060627,GO:0065003,GO:0065007,GO:0070013,GO:0070262,GO:0070301,GO:0070542,GO:0070727,GO:0070887,GO:0071214,GO:0071236,GO:0071241,GO:0071248,GO:0071276,GO:0071478,GO:0071482,GO:0071489,GO:0071704,GO:0071840,GO:0071944,GO:0072347,GO:0072686,GO:0080090,GO:0090056,GO:0090304,GO:0097159,GO:0097237,GO:0097367,GO:0097447,GO:0097458,GO:0097659,GO:0098827,GO:0101031,GO:0104004,GO:0120025,GO:0120038,GO:0140096,GO:1901214,GO:1901215,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901401,GO:1901402,GO:1901463,GO:1901464,GO:1901564,GO:1901576,GO:1901698,GO:1901700,GO:1901701,GO:1902325,GO:1903530,GO:1903531,GO:1904550,GO:1990635,GO:2000322,GO:2000324	3.1.3.16	ko:K04460,ko:K11800	ko04010,map04010	-	-	-	ko00000,ko00001,ko01000,ko01009,ko04121	-	-	-	Metallophos,PPP5,TPR_1,TPR_8
LZS2_k127_8568377_1	485913.Krac_8263	4.155e-165	527.0	COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
LZS2_k127_8568377_2	653045.Strvi_8487	2.371e-141	463.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2GIXE@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
LZS2_k127_8568377_0	986075.CathTA2_1034	1.373e-216	683.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS2_k127_8568377_4	431947.PGN_0361	8.21e-10	62.0	COG1216@1|root,COG1216@2|Bacteria,4NFW5@976|Bacteroidetes,2FQ14@200643|Bacteroidia,22X88@171551|Porphyromonadaceae	976|Bacteroidetes	S	Glycosyl transferase family group 2	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
LZS2_k127_8572717_1	1499967.BAYZ01000041_gene2397	8.251e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,2NRIR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_8572717_0	13035.Dacsa_1650	2.482e-239	766.0	COG0249@1|root,COG0249@2|Bacteria,1G1QX@1117|Cyanobacteria	1117|Cyanobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
LZS2_k127_8578651_1	644107.SL1157_3177	5.92e-46	175.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,4NBK1@97050|Ruegeria	28211|Alphaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
LZS2_k127_8578651_0	1173021.ALWA01000020_gene220	1.973e-77	274.0	COG0436@1|root,COG0436@2|Bacteria,1G202@1117|Cyanobacteria	1117|Cyanobacteria	E	Aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_8611972_4	909663.KI867150_gene702	6.127e-38	161.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2MQBE@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS2_k127_8611972_5	748449.Halha_2435	1.208e-25	119.0	COG0795@1|root,COG0795@2|Bacteria,1UZNX@1239|Firmicutes,24F8X@186801|Clostridia,3WAEC@53433|Halanaerobiales	186801|Clostridia	M	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
LZS2_k127_8611972_2	234267.Acid_2705	9.629e-86	320.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS2_k127_8611972_0	123214.PERMA_1058	1.527e-135	445.0	COG0001@1|root,COG0001@2|Bacteria,2G3VU@200783|Aquificae	200783|Aquificae	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_8611972_7	1128427.KB904821_gene190	3.627e-06	60.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_8611972_3	1298593.TOL_2207	2.812e-39	155.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_8611972_1	604354.TSIB_2051	3.656e-113	378.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,243U2@183968|Thermococci	183968|Thermococci	E	Beta-eliminating lyase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_8611972_6	292564.Cyagr_3228	4.218e-20	91.0	COG0451@1|root,COG0451@2|Bacteria,1GDMD@1117|Cyanobacteria,22TDW@167375|Cyanobium	1117|Cyanobacteria	GM	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS2_k127_8625275_0	161934.XP_010693387.1	7.891e-09	69.0	COG0457@1|root,KOG1840@2759|Eukaryota,37Q20@33090|Viridiplantae,3GGHD@35493|Streptophyta	35493|Streptophyta	Z	kinesin light chain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_7,TPR_8
LZS2_k127_8626411_6	1424334.W822_01225	2.814e-06	55.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,3T22Y@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
LZS2_k127_8626411_0	204669.Acid345_1443	1.091e-114	388.0	COG1012@1|root,COG1012@2|Bacteria,3Y6J2@57723|Acidobacteria,2JMD6@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
LZS2_k127_8626411_1	401526.TcarDRAFT_0036	9.626e-99	335.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4H31K@909932|Negativicutes	909932|Negativicutes	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS2_k127_8626411_2	1401067.HMPREF0872_00825	1.049e-61	226.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4H33N@909932|Negativicutes	909932|Negativicutes	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
LZS2_k127_8626411_3	410358.Mlab_1152	1.207e-46	179.0	COG1120@1|root,arCOG00198@2157|Archaea,2XV8E@28890|Euryarchaeota,2NAEF@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
LZS2_k127_8626411_5	525367.HMPREF0556_12341	1.485e-17	89.0	COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli,26KK3@186820|Listeriaceae	91061|Bacilli	M	Diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07900	DAGK_prokar
LZS2_k127_8626411_4	398512.JQKC01000013_gene1347	1.983e-28	119.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
LZS2_k127_8627465_0	1123320.KB889664_gene965	2.878e-38	164.0	COG0515@1|root,COG0515@2|Bacteria,2IA1X@201174|Actinobacteria	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_8629237_0	443143.GM18_0952	1.117e-51	201.0	COG0438@1|root,COG0438@2|Bacteria,1MWVX@1224|Proteobacteria,42WEG@68525|delta/epsilon subdivisions,2WWQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
LZS2_k127_8632078_2	69042.WH5701_11004	3.358e-51	198.0	COG0739@1|root,COG0739@2|Bacteria,1GPPW@1117|Cyanobacteria,1H3N4@1129|Synechococcus	1117|Cyanobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_8632078_5	398767.Glov_2773	1.123e-08	68.0	COG0745@1|root,COG0745@2|Bacteria,1NQ8U@1224|Proteobacteria,42XVU@68525|delta/epsilon subdivisions,2WTFF@28221|Deltaproteobacteria,43VV3@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
LZS2_k127_8632078_1	349521.HCH_04045	2.513e-51	191.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1RPXT@1236|Gammaproteobacteria,1XS7F@135619|Oceanospirillales	135619|Oceanospirillales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS2_k127_8632078_4	176280.SE_0969	6.047e-26	118.0	COG4195@1|root,COG4195@2|Bacteria,1VBQ5@1239|Firmicutes,4HK5Q@91061|Bacilli,4GYYK@90964|Staphylococcaceae	91061|Bacilli	S	phage-related replication protein	ymaC	-	-	-	-	-	-	-	-	-	-	-	Gamma_PGA_hydro
LZS2_k127_8632078_0	1297742.A176_01519	3.253e-54	201.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,4389R@68525|delta/epsilon subdivisions,2XA3N@28221|Deltaproteobacteria,2YWAI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
LZS2_k127_8632078_3	1254432.SCE1572_34485	1.226e-33	147.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4346X@68525|delta/epsilon subdivisions,2XA3R@28221|Deltaproteobacteria,2YXWE@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TonB_C
LZS2_k127_8634088_0	686340.Metal_2426	1.143e-91	329.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1RX1G@1236|Gammaproteobacteria,1XG47@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
LZS2_k127_8634088_1	1229172.JQFA01000002_gene4747	1.582e-10	73.0	COG1357@1|root,COG2214@1|root,COG1357@2|Bacteria,COG2214@2|Bacteria,1G530@1117|Cyanobacteria,1H8Q1@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,Pentapeptide
LZS2_k127_8637872_0	1340493.JNIF01000004_gene877	2.605e-11	74.0	2EU62@1|root,33MNN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
LZS2_k127_8642320_0	290317.Cpha266_2356	4.102e-32	133.0	COG1215@1|root,COG1215@2|Bacteria,1FDR6@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_8642320_2	1379270.AUXF01000007_gene1028	7.014e-27	115.0	COG5528@1|root,COG5528@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2269)	mchD	-	-	-	-	-	-	-	-	-	-	-	DUF2269
LZS2_k127_8642320_1	448385.sce0582	5.071e-29	123.0	COG0644@1|root,COG0644@2|Bacteria,1Q2PR@1224|Proteobacteria,438AZ@68525|delta/epsilon subdivisions,2X3KA@28221|Deltaproteobacteria,2YWEC@29|Myxococcales	28221|Deltaproteobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8647580_1	1121106.JQKB01000004_gene2274	4.829e-43	159.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,2JREK@204441|Rhodospirillales	204441|Rhodospirillales	G	Maltogenic Amylase, C-terminal domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
LZS2_k127_8647580_0	255470.cbdbA801	2.193e-163	527.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi,34D7J@301297|Dehalococcoidia	301297|Dehalococcoidia	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
LZS2_k127_8647580_2	673860.AciM339_1205	2.788e-11	70.0	COG1371@1|root,arCOG04055@2157|Archaea,2Y6XM@28890|Euryarchaeota,3F2S4@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	-	-	-	-	-	-	-	-	-	-	-	Archease
LZS2_k127_8650445_0	82654.Pse7367_0945	3.682e-191	604.0	COG0499@1|root,COG0499@2|Bacteria,1G1MN@1117|Cyanobacteria,1H7TX@1150|Oscillatoriales	1117|Cyanobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS2_k127_8650445_1	102129.Lepto7375DRAFT_4007	1.202e-102	339.0	COG0745@1|root,COG0745@2|Bacteria,1G0YA@1117|Cyanobacteria,1H7GK@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rpaB	-	-	ko:K11329	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_8650445_2	1123288.SOV_2c07690	0.0002827	53.0	COG4964@1|root,COG4964@2|Bacteria,1U35M@1239|Firmicutes,4H2C4@909932|Negativicutes	909932|Negativicutes	U	PFAM type II and III secretion system protein	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
LZS2_k127_8670751_2	797114.C475_12497	1.522e-06	55.0	COG0784@1|root,arCOG02589@2157|Archaea,2XVUK@28890|Euryarchaeota,23V7T@183963|Halobacteria	183963|Halobacteria	T	response regulator, receiver	rre-1	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
LZS2_k127_8670751_1	1173028.ANKO01000195_gene5992	7.017e-54	206.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HH3F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
LZS2_k127_8670751_0	1469607.KK073768_gene3658	4.859e-108	361.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1HJYZ@1161|Nostocales	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS2_k127_8673123_1	469381.Dpep_0462	4.168e-09	70.0	COG0860@1|root,COG0860@2|Bacteria,3T9S8@508458|Synergistetes	508458|Synergistetes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
LZS2_k127_8673123_0	132113.XP_003493232.1	2.511e-13	83.0	2CHVS@1|root,2S3Q2@2759|Eukaryota,3A744@33154|Opisthokonta,3BTNY@33208|Metazoa,3D9YA@33213|Bilateria,420FF@6656|Arthropoda,3SNVI@50557|Insecta	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_868057_1	498761.HM1_1939	5.13e-95	325.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
LZS2_k127_868057_2	1150474.JQJI01000002_gene1207	1.27e-37	152.0	COG0095@1|root,COG0095@2|Bacteria,2GD62@200918|Thermotogae	200918|Thermotogae	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
LZS2_k127_868057_0	471223.GWCH70_2254	6.57e-122	404.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,1WEBN@129337|Geobacillus	91061|Bacilli	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	deoA	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
LZS2_k127_868057_3	1341151.ASZU01000017_gene1778	1.438e-31	134.0	COG1427@1|root,COG1427@2|Bacteria,1V2PX@1239|Firmicutes,4HFX0@91061|Bacilli,27CMS@186824|Thermoactinomycetaceae	91061|Bacilli	S	Menaquinone biosynthesis	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
LZS2_k127_868057_4	388467.A19Y_0200	6.525e-14	85.0	COG0457@1|root,COG4421@1|root,COG0457@2|Bacteria,COG4421@2|Bacteria,1G2V7@1117|Cyanobacteria,1H9R5@1150|Oscillatoriales	1117|Cyanobacteria	G	TPR repeat Sel1-like repeat Tetratricopeptide TPR_3 Tetratricopeptide TPR_2	-	-	-	-	-	-	-	-	-	-	-	-	DUF563,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
LZS2_k127_8692792_2	1122947.FR7_2687	9.288e-74	258.0	COG0697@1|root,COG0697@2|Bacteria,1V230@1239|Firmicutes,4H6TY@909932|Negativicutes	909932|Negativicutes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_8692792_1	443143.GM18_0083	1.66e-82	286.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNUR@28221|Deltaproteobacteria,43TZW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS2_k127_8692792_4	1123393.KB891330_gene879	0.0002269	53.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,1KS68@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
LZS2_k127_8692792_0	10224.XP_002740464.1	1.53e-96	326.0	COG1063@1|root,KOG0024@2759|Eukaryota,38BYX@33154|Opisthokonta,3B9JA@33208|Metazoa,3CXF2@33213|Bilateria	33208|Metazoa	Q	Sorbitol dehydrogenase	-	GO:0008150,GO:0030431,GO:0032501	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_8692792_3	1235798.C817_03643	1.239e-27	128.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	gutB	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_8695186_0	1165096.ARWF01000001_gene2387	1.674e-121	412.0	COG5519@1|root,COG5519@2|Bacteria,1MW5H@1224|Proteobacteria,2VHZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Domain of unknown function (DUF927)	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	DUF927,PriCT_2,Toprim_3
LZS2_k127_8695186_1	525146.Ddes_1262	7.15e-08	55.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,42REQ@68525|delta/epsilon subdivisions,2WNVY@28221|Deltaproteobacteria,2M7TB@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve_3
LZS2_k127_8702084_0	1121346.KB899855_gene106	2.485e-124	413.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,26R9D@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
LZS2_k127_8702084_1	243232.MJ_0967	7.241e-42	161.0	COG0693@1|root,arCOG00769@2157|Archaea,2XTPH@28890|Euryarchaeota,23QVZ@183939|Methanococci	183939|Methanococci	O	PFAM ThiJ PfpI domain protein	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
LZS2_k127_870614_1	1340493.JNIF01000004_gene664	6.78e-49	184.0	COG1656@1|root,COG1656@2|Bacteria,3Y4NR@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
LZS2_k127_870614_2	1304883.KI912532_gene1222	6.525e-44	168.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,2WGZK@28216|Betaproteobacteria,2KW1W@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
LZS2_k127_870614_0	522306.CAP2UW1_0241	3.611e-112	372.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,2VJ2P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SPFH domain Band 7 family protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,SHOCT
LZS2_k127_870614_3	883126.HMPREF9710_05169	9.147e-10	65.0	2DRCV@1|root,33B8R@2|Bacteria,1R3NN@1224|Proteobacteria	1224|Proteobacteria	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
LZS2_k127_870682_4	932213.SPM24T3_14486	5.044e-53	191.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,1RPAG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1020 Non-ribosomal peptide synthetase modules and related proteins	pltF	GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249	-	ko:K16126,ko:K21780	ko00333,ko01054,map00333,map01054	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
LZS2_k127_870682_1	533247.CRD_02157	2.306e-117	391.0	COG0156@1|root,COG0454@1|root,COG0156@2|Bacteria,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652,ko:K13614,ko:K15674	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01004,ko01007,ko01008	-	-	-	Acetyltransf_1,Aminotran_1_2,DinB_2,EAL,GGDEF,KAsynt_C_assoc,Ketoacyl-synt_C,PAS_4,PP-binding,ketoacyl-synt
LZS2_k127_870682_6	717606.PaecuDRAFT_2501	8.206e-08	65.0	COG2308@1|root,COG2308@2|Bacteria,1TPA5@1239|Firmicutes,4HE51@91061|Bacilli,26UNZ@186822|Paenibacillaceae	91061|Bacilli	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
LZS2_k127_870682_5	1121875.KB907547_gene2992	1.04e-11	70.0	COG2149@1|root,COG2149@2|Bacteria,4NZMM@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
LZS2_k127_870682_3	1173028.ANKO01000017_gene204	5.956e-87	304.0	COG0604@1|root,COG0604@2|Bacteria,1GD4E@1117|Cyanobacteria,1HEHU@1150|Oscillatoriales	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_870682_2	1538295.JY96_17645	6.516e-99	326.0	COG5514@1|root,COG5514@2|Bacteria,1MX90@1224|Proteobacteria,2VIMN@28216|Betaproteobacteria,1KKIT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
LZS2_k127_870682_0	595460.RRSWK_05971	0.0	1066.0	COG3119@1|root,COG3119@2|Bacteria,2IX0Y@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
LZS2_k127_8710288_1	224324.aq_313	9.8e-07	53.0	COG2107@1|root,COG2107@2|Bacteria,2G4EE@200783|Aquificae	200783|Aquificae	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
LZS2_k127_8710288_0	321332.CYB_0146	8.94e-19	101.0	COG5549@1|root,COG5549@2|Bacteria,1G4CD@1117|Cyanobacteria	1117|Cyanobacteria	O	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
LZS2_k127_8719645_0	857293.CAAU_2065	2.84e-85	293.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,36UMS@31979|Clostridiaceae	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	gyaR	-	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS2_k127_8719645_1	1207076.ALAT01000180_gene2204	3.564e-29	128.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Lipase_GDSL_2
LZS2_k127_8719645_2	857293.CAAU_2105	1.298e-27	121.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,36ETW@31979|Clostridiaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
LZS2_k127_8720552_1	378806.STAUR_5834	0.0001017	54.0	COG0745@1|root,COG0745@2|Bacteria,1NQ8U@1224|Proteobacteria,42QWX@68525|delta/epsilon subdivisions,2WN80@28221|Deltaproteobacteria,2YXRS@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
LZS2_k127_8720552_0	395961.Cyan7425_4105	2.982e-53	211.0	COG1413@1|root,COG2319@1|root,COG1413@2|Bacteria,COG2319@2|Bacteria,1G6AT@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM Leucine rich repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	LRV
LZS2_k127_8723180_5	1128421.JAGA01000003_gene3091	2.278e-16	91.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_8723180_6	344747.PM8797T_27627	4.037e-07	55.0	COG0224@1|root,COG0224@2|Bacteria,2J3E7@203682|Planctomycetes	203682|Planctomycetes	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
LZS2_k127_8723180_4	522772.Dacet_2779	3.598e-38	154.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.95	ko:K05928	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07236,R07504,R10491,R10492	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
LZS2_k127_8723180_3	269796.Rru_A2761	5.503e-46	186.0	COG1835@1|root,COG1835@2|Bacteria,1PB64@1224|Proteobacteria,2U3A1@28211|Alphaproteobacteria,2JUWB@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
LZS2_k127_8723180_1	1123276.KB893312_gene3090	1.822e-110	369.0	COG0665@1|root,COG0665@2|Bacteria,4NKQK@976|Bacteroidetes,47Q2W@768503|Cytophagia	976|Bacteroidetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
LZS2_k127_8723180_0	228410.NE2167	5.478e-121	400.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,371WX@32003|Nitrosomonadales	28216|Betaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_8723180_2	573569.F7308_0863	1.663e-84	285.0	COG0224@1|root,COG0224@2|Bacteria,1QUME@1224|Proteobacteria,1S2EG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
LZS2_k127_8723278_4	1231057.AMGD01000020_gene3278	6.977e-14	73.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HADX@91061|Bacilli,26EBA@186818|Planococcaceae	91061|Bacilli	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
LZS2_k127_8723278_3	457570.Nther_0910	9.315e-46	177.0	COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,248NA@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03525	GHMP_kinases_C,GHMP_kinases_N
LZS2_k127_8723278_0	224324.aq_425	1.361e-137	446.0	COG0498@1|root,COG0498@2|Bacteria,2G3NU@200783|Aquificae	200783|Aquificae	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC_2	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_8723278_1	1121335.Clst_0288	3.225e-102	347.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGKB@541000|Ruminococcaceae	186801|Clostridia	E	Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
LZS2_k127_8723278_2	1378168.N510_02924	6.38e-52	201.0	COG0790@1|root,COG0790@2|Bacteria,1TS5X@1239|Firmicutes	1239|Firmicutes	KLT	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
LZS2_k127_8727021_2	1122152.AUEI01000004_gene772	1.299e-47	192.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_8727021_1	1267535.KB906767_gene1129	2.391e-52	205.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria,2JJ7M@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_8727021_0	309801.trd_A0628	0.0	1297.0	COG0243@1|root,COG0243@2|Bacteria,2GABT@200795|Chloroflexi,27Z9X@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS2_k127_8727021_3	391625.PPSIR1_23464	2.076e-07	56.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,2Z16M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
LZS2_k127_8735721_0	234267.Acid_6552	1.965e-109	365.0	COG0409@1|root,COG0409@2|Bacteria,3Y405@57723|Acidobacteria	57723|Acidobacteria	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
LZS2_k127_8735721_1	936375.HMPREF1152_0313	6.303e-78	274.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WCCM@538999|Clostridiales incertae sedis	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_8735721_2	1303518.CCALI_00309	1.161e-24	114.0	COG2365@1|root,COG2365@2|Bacteria	2|Bacteria	T	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	DSPc,DUF442,PTPlike_phytase,Y_phosphatase2,Y_phosphatase3
LZS2_k127_8745443_0	1379698.RBG1_1C00001G1217	6.5e-191	616.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2NP05@2323|unclassified Bacteria	2|Bacteria	H	Methylenetetrahydrofolate reductase	yitJ	-	1.5.1.20,2.1.1.10,2.1.1.13	ko:K00297,ko:K00547,ko:K00548	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523	M00017,M00377	R00650,R00946,R01224,R07168,R09365	RC00003,RC00035,RC00081,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
LZS2_k127_8745443_2	522306.CAP2UW1_2075	4.006e-20	101.0	COG0457@1|root,COG3012@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3012@2|Bacteria,COG3903@2|Bacteria,1MWRF@1224|Proteobacteria,2VVW1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_7
LZS2_k127_8745443_3	1288484.APCS01000011_gene983	0.0001714	53.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,LRV
LZS2_k127_8745443_1	661478.OP10G_3996	3.612e-27	111.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS2_k127_8747984_0	1173024.KI912148_gene4571	3.784e-283	885.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1JMTM@1189|Stigonemataceae	1117|Cyanobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS2_k127_8771755_0	1469607.KK073768_gene1727	1.144e-162	533.0	COG2804@1|root,COG2804@2|Bacteria,1G03J@1117|Cyanobacteria,1HK88@1161|Nostocales	1117|Cyanobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
LZS2_k127_877696_0	1173021.ALWA01000028_gene1988	5.5e-128	429.0	COG0751@1|root,COG0751@2|Bacteria,1G0QU@1117|Cyanobacteria	1117|Cyanobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iJN678.glyS	DALR_1,tRNA_synt_2f
LZS2_k127_877696_1	864565.HMPREF0379_1622	9.787e-32	140.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia	186801|Clostridia	KLT	PFAM KWG Leptospira repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
LZS2_k127_878103_0	1121939.L861_12410	2.091e-48	175.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria,1XNV3@135619|Oceanospirillales	135619|Oceanospirillales	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
LZS2_k127_878103_1	1120973.AQXL01000135_gene1317	6.721e-15	80.0	COG1659@1|root,COG1659@2|Bacteria,1UR7R@1239|Firmicutes,4HCW3@91061|Bacilli	91061|Bacilli	S	Encapsulating protein for peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Linocin_M18
LZS2_k127_87846_1	1120925.F941_02026	4.396e-08	61.0	COG2503@1|root,COG2503@2|Bacteria,1PXPQ@1224|Proteobacteria,1TBI2@1236|Gammaproteobacteria,3NQWE@468|Moraxellaceae	1236|Gammaproteobacteria	M	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
LZS2_k127_87846_0	644966.Tmar_0103	6.712e-22	98.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3WCKQ@538999|Clostridiales incertae sedis	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS2_k127_8795093_0	517418.Ctha_1347	4.275e-106	354.0	COG0527@1|root,COG0527@2|Bacteria,1FDBX@1090|Chlorobi	1090|Chlorobi	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
LZS2_k127_881427_0	273068.TTE0463	6.186e-121	401.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,42F24@68295|Thermoanaerobacterales	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
LZS2_k127_881427_2	1395587.P364_0126230	2.807e-13	77.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,26RZJ@186822|Paenibacillaceae	91061|Bacilli	F	Phosphorylase superfamily	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
LZS2_k127_881427_1	28737.XP_006883339.1	8.086e-36	147.0	COG0005@1|root,KOG3984@2759|Eukaryota,38BI3@33154|Opisthokonta,3BDDV@33208|Metazoa,3CUH9@33213|Bilateria,47ZIF@7711|Chordata,48XWD@7742|Vertebrata,3J6V4@40674|Mammalia,352X6@311790|Afrotheria	33208|Metazoa	F	Purine nucleoside	PNP	GO:0001775,GO:0001816,GO:0001882,GO:0001910,GO:0001912,GO:0001914,GO:0001916,GO:0002054,GO:0002060,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0002697,GO:0002699,GO:0002703,GO:0002705,GO:0002706,GO:0002708,GO:0002709,GO:0002711,GO:0002790,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006148,GO:0006149,GO:0006152,GO:0006161,GO:0006163,GO:0006164,GO:0006183,GO:0006195,GO:0006282,GO:0006725,GO:0006732,GO:0006733,GO:0006738,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006915,GO:0006950,GO:0006955,GO:0006974,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008617,GO:0008630,GO:0008637,GO:0009056,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009120,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009151,GO:0009152,GO:0009163,GO:0009164,GO:0009165,GO:0009166,GO:0009199,GO:0009200,GO:0009201,GO:0009205,GO:0009206,GO:0009215,GO:0009259,GO:0009260,GO:0009262,GO:0009306,GO:0009314,GO:0009394,GO:0009435,GO:0009628,GO:0009893,GO:0009987,GO:0010212,GO:0010332,GO:0010604,GO:0010941,GO:0012501,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0016192,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019692,GO:0019693,GO:0022407,GO:0022409,GO:0023052,GO:0030141,GO:0030155,GO:0031323,GO:0031325,GO:0031341,GO:0031343,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032501,GO:0032623,GO:0032940,GO:0032944,GO:0032946,GO:0033036,GO:0033554,GO:0034356,GO:0034404,GO:0034418,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0034774,GO:0035556,GO:0036094,GO:0036230,GO:0042102,GO:0042119,GO:0042127,GO:0042129,GO:0042221,GO:0042278,GO:0042301,GO:0042451,GO:0042453,GO:0042454,GO:0042455,GO:0042493,GO:0042886,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045184,GO:0045321,GO:0045577,GO:0045579,GO:0045580,GO:0045582,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045739,GO:0045785,GO:0045935,GO:0046039,GO:0046070,GO:0046094,GO:0046102,GO:0046115,GO:0046121,GO:0046122,GO:0046124,GO:0046128,GO:0046129,GO:0046130,GO:0046390,GO:0046415,GO:0046434,GO:0046483,GO:0046495,GO:0046496,GO:0046634,GO:0046635,GO:0046637,GO:0046638,GO:0046700,GO:0046903,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050663,GO:0050670,GO:0050671,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050863,GO:0050864,GO:0050865,GO:0050867,GO:0050870,GO:0050871,GO:0050896,GO:0051052,GO:0051054,GO:0051094,GO:0051171,GO:0051173,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051239,GO:0051240,GO:0051249,GO:0051251,GO:0051716,GO:0055086,GO:0060205,GO:0060255,GO:0060548,GO:0065007,GO:0070013,GO:0070228,GO:0070229,GO:0070232,GO:0070233,GO:0070637,GO:0070638,GO:0070663,GO:0070665,GO:0070970,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072521,GO:0072522,GO:0072523,GO:0072524,GO:0072525,GO:0072526,GO:0080090,GO:0080134,GO:0080135,GO:0090407,GO:0097159,GO:0097190,GO:0097193,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901068,GO:1901069,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659,GO:1902105,GO:1902107,GO:1903037,GO:1903039,GO:1903706,GO:1903708,GO:1904813,GO:2000026,GO:2000106,GO:2000107,GO:2001020,GO:2001022	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS2_k127_8820302_2	1089549.AZUQ01000001_gene2992	4.398e-08	64.0	2DVKU@1|root,33WAK@2|Bacteria,2I4U3@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS2_k127_8820302_0	862908.BMS_1056	7.219e-97	333.0	COG1874@1|root,COG1874@2|Bacteria,1R8CV@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolase family 14	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_14
LZS2_k127_8820302_1	1173021.ALWA01000028_gene1978	3.017e-78	274.0	COG3854@1|root,COG3854@2|Bacteria,1G0U1@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	ycf45	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
LZS2_k127_8825913_1	502025.Hoch_6859	9.163e-55	196.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2YV8N@29|Myxococcales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
LZS2_k127_8825913_0	756272.Plabr_3034	4.732e-108	360.0	COG0591@1|root,COG0591@2|Bacteria,2J22E@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS2_k127_8828236_0	392500.Swoo_4045	5.598e-45	169.0	2C4KU@1|root,32RE6@2|Bacteria,1RBD1@1224|Proteobacteria,1S1BE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8833022_0	944479.JQLX01000014_gene1500	1.348e-153	495.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria,2M6BS@213113|Desulfurellales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1825	AMP-binding,AMP-binding_C_2
LZS2_k127_8844678_1	1282362.AEAC466_07640	6.074e-74	252.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,2KF0A@204458|Caulobacterales	204458|Caulobacterales	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
LZS2_k127_8844678_0	1121022.ABENE_03085	2.12e-220	696.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2KEXP@204458|Caulobacterales	204458|Caulobacterales	H	acetolactate synthase large subunit	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS2_k127_8853237_1	1521187.JPIM01000016_gene3681	7.117e-28	123.0	2ARTX@1|root,31H5E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8853237_0	118173.KB235910_gene4714	3.651e-229	736.0	COG0542@1|root,COG0542@2|Bacteria,1G0ZH@1117|Cyanobacteria,1H8UC@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_8862747_1	225937.HP15_3803	1.713e-23	108.0	COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria,1T1UD@1236|Gammaproteobacteria,46A7X@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_9,dCache_1
LZS2_k127_8862747_0	411469.EUBHAL_01247	1.865e-83	284.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,25UXN@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
LZS2_k127_8862982_0	886293.Sinac_3564	1.24e-153	505.0	COG0659@1|root,COG0659@2|Bacteria,2IXYR@203682|Planctomycetes	203682|Planctomycetes	P	Sulfate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
LZS2_k127_8862982_3	904306.HMPREF9192_1401	3.033e-05	53.0	COG5340@1|root,COG5340@2|Bacteria,1U7YG@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8862982_1	251221.35210665	1.276e-22	100.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	ydaS	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
LZS2_k127_8862982_2	1121374.KB891575_gene1184	2.972e-09	65.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1S5FN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Radical SAM superfamily	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
LZS2_k127_8863337_0	632245.CLP_1787	5.553e-34	134.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,36DGY@31979|Clostridiaceae	186801|Clostridia	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
LZS2_k127_8863337_5	2325.TKV_c18910	1.516e-05	49.0	COG0864@1|root,COG0864@2|Bacteria,1VA28@1239|Firmicutes,24QKP@186801|Clostridia,42GK0@68295|Thermoanaerobacterales	186801|Clostridia	K	transcriptional regulator, CopG family	-	-	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
LZS2_k127_8863337_2	329726.AM1_3584	2.716e-13	83.0	COG1266@1|root,COG1266@2|Bacteria,1G0ZJ@1117|Cyanobacteria	1117|Cyanobacteria	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS2_k127_8863337_1	5016.M2UC89	2.316e-13	83.0	COG0457@1|root,KOG1840@2759|Eukaryota,39WGH@33154|Opisthokonta,3PF1F@4751|Fungi,3QS3C@4890|Ascomycota,209IX@147541|Dothideomycetes	4751|Fungi	Z	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	HET,NB-ARC,PNP_UDP_1,Patatin,TPR_10,TPR_12,TPR_7
LZS2_k127_8863337_3	1185876.BN8_04189	5.965e-13	79.0	COG0457@1|root,COG0457@2|Bacteria,4NJ7X@976|Bacteroidetes,47NJZ@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_8863337_4	452863.Achl_1009	6.764e-07	55.0	COG0514@1|root,COG0514@2|Bacteria,2GJSS@201174|Actinobacteria,1W8J4@1268|Micrococcaceae	201174|Actinobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,DUF3553,Helicase_C,RecQ_Zn_bind
LZS2_k127_8872240_0	525904.Tter_2194	1.02e-129	453.0	COG0745@1|root,COG2197@1|root,COG2202@1|root,COG3829@1|root,COG4251@1|root,COG0745@2|Bacteria,COG2197@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	ko:K03413,ko:K07684,ko:K07689	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00471,M00475,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	GAF,GAF_2,GerE,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg,SBP_bac_3
LZS2_k127_8878224_0	1122137.AQXF01000003_gene2481	1.513e-141	459.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2U2YT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
LZS2_k127_8878224_3	55529.EKX47332	0.0003989	50.0	2CXIA@1|root,2RXSU@2759|Eukaryota	2759|Eukaryota	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
LZS2_k127_8878224_2	1123277.KB893174_gene6040	0.0001153	52.0	COG2020@1|root,COG2020@2|Bacteria,4NTXI@976|Bacteroidetes,47RFP@768503|Cytophagia	976|Bacteroidetes	O	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU,PEMT
LZS2_k127_8878224_1	243090.RB10853	1.503e-13	79.0	COG2267@1|root,COG2267@2|Bacteria,2IZH7@203682|Planctomycetes	203682|Planctomycetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS2_k127_8888340_1	234267.Acid_7037	0.0001661	52.0	COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria	57723|Acidobacteria	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
LZS2_k127_888989_0	373903.Hore_02300	4.205e-177	578.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WA7S@53433|Halanaerobiales	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS2_k127_888989_2	1122931.AUAE01000005_gene3217	2.107e-06	59.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,2FPQX@200643|Bacteroidia,22WF4@171551|Porphyromonadaceae	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarboxypepD_reg,OmpA,PD40
LZS2_k127_888989_1	1122221.JHVI01000010_gene2524	1.002e-17	84.0	COG1024@1|root,COG1024@2|Bacteria,1WIYN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Enoyl-CoA hydratase isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
LZS2_k127_8895237_0	251221.35213769	3.064e-79	272.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1G092@1117|Cyanobacteria	1117|Cyanobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
LZS2_k127_8895237_1	1423780.LOT_0126	3.746e-23	106.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli,3F3MR@33958|Lactobacillaceae	91061|Bacilli	O	Hydrolase, P-loop family	ydiB	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
LZS2_k127_8896435_2	1408813.AYMG01000003_gene2880	5.467e-16	86.0	COG0705@1|root,COG0705@2|Bacteria,4NP9G@976|Bacteroidetes,1IUQ8@117747|Sphingobacteriia	976|Bacteroidetes	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
LZS2_k127_8896435_1	102232.GLO73106DRAFT_00013210	1.053e-50	191.0	COG2267@1|root,COG2267@2|Bacteria,1G14K@1117|Cyanobacteria	1117|Cyanobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_8896435_0	43989.cce_4151	1.116e-95	327.0	COG0156@1|root,COG0156@2|Bacteria,1FZY9@1117|Cyanobacteria,3KH0U@43988|Cyanothece	1117|Cyanobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.bioF	Aminotran_1_2
LZS2_k127_8896435_3	167546.P9301_16591	5.494e-05	51.0	COG0400@1|root,COG0400@2|Bacteria,1GC26@1117|Cyanobacteria,1MMED@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	3.1.1.85	ko:K19560	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	-
LZS2_k127_8908089_4	1246626.BleG1_2325	4.579e-14	76.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,1ZGBF@1386|Bacillus	91061|Bacilli	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
LZS2_k127_8908089_2	941824.TCEL_01789	9.55e-90	307.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,36EAK@31979|Clostridiaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS2_k127_8908089_3	195250.CM001776_gene2877	3.564e-44	166.0	COG1259@1|root,COG1259@2|Bacteria,1G4YX@1117|Cyanobacteria,1H0I1@1129|Synechococcus	1117|Cyanobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
LZS2_k127_8908089_0	251221.35214980	4.774e-203	645.0	COG0433@1|root,COG0433@2|Bacteria,1FZWV@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM HAS barrel domain	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
LZS2_k127_8908089_5	452637.Oter_4390	3.15e-11	68.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	pchC	-	-	ko:K00406,ko:K20200	ko00190,ko00623,ko01100,ko01120,ko02020,map00190,map00623,map01100,map01120,map02020	M00156	R02675,R11194	RC00769	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
LZS2_k127_8908089_1	1121423.JONT01000003_gene1044	3.976e-136	446.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,260JC@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
LZS2_k127_8908089_6	382464.ABSI01000005_gene1018	5.829e-11	66.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia,2ITJM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
LZS2_k127_8914011_0	1444712.BN1013_02011	7.427e-45	173.0	COG0363@1|root,COG0363@2|Bacteria,2JFZ0@204428|Chlamydiae	204428|Chlamydiae	G	6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
LZS2_k127_8920746_0	517418.Ctha_0233	1.554e-34	137.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1FDRS@1090|Chlorobi	1090|Chlorobi	C	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
LZS2_k127_8920746_1	1230341.MJ3_03977	1.492e-26	114.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,4HH7Z@91061|Bacilli	91061|Bacilli	O	Peroxiredoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS2_k127_8920746_2	419665.Maeo_0695	3.836e-09	67.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota,23R2D@183939|Methanococci	183939|Methanococci	S	PFAM Roadblock LC7 family protein	-	GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
LZS2_k127_8921024_0	176299.Atu3770	3.49e-41	167.0	COG0737@1|root,COG1652@1|root,COG0737@2|Bacteria,COG1652@2|Bacteria,1MX03@1224|Proteobacteria,2TTUP@28211|Alphaproteobacteria,4B7W3@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Belongs to the 5'-nucleotidase family	MA20_07595	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos
LZS2_k127_8921024_1	1461580.CCAS010000052_gene3649	5.787e-36	144.0	28M7B@1|root,2ZAKT@2|Bacteria,1TQPQ@1239|Firmicutes,4HX95@91061|Bacilli	91061|Bacilli	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8921024_2	247490.KSU1_D1057	1.128e-17	86.0	COG0457@1|root,COG0457@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_8927757_0	1144312.PMI09_00592	1.994e-205	650.0	COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,2TUR1@28211|Alphaproteobacteria,4B93D@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
LZS2_k127_8927757_1	1297742.A176_07477	7.287e-11	76.0	29QU6@1|root,30BU6@2|Bacteria,1NKTK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8927757_3	530564.Psta_3778	1.879e-05	58.0	COG0793@1|root,COG0793@2|Bacteria,2IY0G@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS2_k127_8929144_0	742767.HMPREF9456_01977	4.878e-11	73.0	COG3294@1|root,COG3294@2|Bacteria,4NJAE@976|Bacteroidetes,2FNKA@200643|Bacteroidia,22WQF@171551|Porphyromonadaceae	976|Bacteroidetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
LZS2_k127_8930573_0	1128398.Curi_c18540	1.033e-108	361.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,2683V@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS2_k127_8930573_1	1128398.Curi_c18530	3.214e-102	342.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,267WZ@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
LZS2_k127_8933635_2	660470.Theba_2099	1.372e-25	110.0	COG0524@1|root,COG0524@2|Bacteria,2GC4R@200918|Thermotogae	200918|Thermotogae	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS2_k127_8933635_0	35754.JNYJ01000047_gene3444	2.493e-217	691.0	COG0531@1|root,COG0531@2|Bacteria,2GM81@201174|Actinobacteria,4DA9Q@85008|Micromonosporales	201174|Actinobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8933635_1	1192034.CAP_6021	2.626e-58	206.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria,2YZM4@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_8933709_0	1265845.PWEIH_07866	8.259e-15	90.0	COG1388@1|root,COG3209@1|root,COG1388@2|Bacteria,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,26JAK@186820|Listeriaceae	91061|Bacilli	M	RHS family	wapA	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	RHS_repeat
LZS2_k127_8933709_1	1502852.FG94_00019	4.551e-13	72.0	COG3608@1|root,COG3608@2|Bacteria,1PBZ4@1224|Proteobacteria,2VMFQ@28216|Betaproteobacteria,473ZS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Succinylglutamate desuccinylase / Aspartoacylase family	astE	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
LZS2_k127_8935367_0	1437824.BN940_07671	4.905e-166	544.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2VTNQ@28216|Betaproteobacteria,3T83X@506|Alcaligenaceae	28216|Betaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
LZS2_k127_896844_0	1340493.JNIF01000004_gene1192	1.285e-27	130.0	COG3451@1|root,COG3451@2|Bacteria	2|Bacteria	U	multi-organism process	traC	-	-	ko:K12063	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	AAA_10,DUF3875,DUF87,TraC_F_IV
LZS2_k127_898172_0	1121090.KB894700_gene3295	2.236e-109	362.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4IU6J@91061|Bacilli	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
LZS2_k127_898172_1	1124780.ANNU01000058_gene886	2.881e-98	328.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS2_k127_898172_2	1356854.N007_19520	5.414e-53	192.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli	91061|Bacilli	I	Belongs to the enoyl-CoA hydratase isomerase family	paaG	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
LZS2_k127_899013_0	1048983.EL17_15200	0.0	1105.0	COG1429@1|root,COG3411@1|root,COG1429@2|Bacteria,COG3411@2|Bacteria,4NHR3@976|Bacteroidetes,47P22@768503|Cytophagia	976|Bacteroidetes	H	CobN/Magnesium Chelatase	-	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel
LZS2_k127_904668_1	649638.Trad_1962	4.06e-35	137.0	COG4989@1|root,COG4989@2|Bacteria,1WMFY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS2_k127_904668_0	1231057.AMGD01000004_gene2896	3.867e-154	497.0	COG0673@1|root,COG0673@2|Bacteria,1TSUT@1239|Firmicutes,4HDBM@91061|Bacilli	91061|Bacilli	S	oxidoreductase	yteT	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_907250_4	756272.Plabr_0460	3.21e-19	93.0	COG0515@1|root,COG0515@2|Bacteria,2IXXT@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS2_k127_907250_1	502025.Hoch_5797	2.546e-57	226.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YYKD@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
LZS2_k127_907250_3	251229.Chro_0763	7.554e-27	119.0	2EME3@1|root,33F2Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_907250_0	1173020.Cha6605_5281	8.346e-143	462.0	28PYN@1|root,2ZCI8@2|Bacteria,1G2MM@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative amidoligase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
LZS2_k127_907250_2	118166.JH976537_gene4380	3.077e-36	139.0	2A5RZ@1|root,30UGZ@2|Bacteria,1GETR@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_921910_3	1122919.KB905624_gene87	4.886e-11	74.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,26QDE@186822|Paenibacillaceae	91061|Bacilli	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
LZS2_k127_921910_2	102107.XP_008228736.1	9.258e-16	89.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37ICC@33090|Viridiplantae,3G9ZF@35493|Streptophyta,4JFG9@91835|fabids	35493|Streptophyta	S	F-box LRR-repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,LRR_6,LRR_8
LZS2_k127_921910_1	435591.BDI_2630	1.995e-23	109.0	COG4639@1|root,COG4639@2|Bacteria,4P3R5@976|Bacteroidetes	976|Bacteroidetes	S	Zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_921910_4	1348635.BBJY01000004_gene2922	1.983e-05	49.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1XSB7@135623|Vibrionales	135623|Vibrionales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_921910_0	1121859.KB890750_gene338	1.477e-95	321.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,47KSG@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
LZS2_k127_943104_1	1056816.JAFQ01000004_gene1864	5.589e-31	139.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4FU85@85025|Nocardiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_943104_0	264462.Bd1353	1.211e-40	156.0	COG0300@1|root,COG0300@2|Bacteria,1PEUB@1224|Proteobacteria,4349H@68525|delta/epsilon subdivisions,2MUAM@213481|Bdellovibrionales,2X2GC@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS2_k127_944163_1	1227495.C487_18963	3.865e-26	121.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1E@28890|Euryarchaeota,23TYX@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_944163_2	331113.SNE_A11760	1.752e-21	99.0	COG1586@1|root,COG1586@2|Bacteria	2|Bacteria	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	2.5.1.16,4.1.1.50	ko:K00797,ko:K01611	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R00178,R01920,R02869,R08359	RC00021,RC00053,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc,Spermine_synt_N,Spermine_synth
LZS2_k127_944163_0	287.DR97_2118	1.734e-69	246.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,1YDQS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
LZS2_k127_945610_0	1089439.KB902271_gene1997	3.58e-140	461.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,4608B@72273|Thiotrichales	72273|Thiotrichales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
LZS2_k127_951661_3	644966.Tmar_1266	3.783e-59	215.0	COG0045@1|root,COG0045@2|Bacteria,1TQG4@1239|Firmicutes,249ED@186801|Clostridia	186801|Clostridia	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
LZS2_k127_951661_0	479433.Caci_6053	1.738e-120	395.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS2_k127_951661_1	748449.Halha_0892	1.17e-92	317.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WAED@53433|Halanaerobiales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
LZS2_k127_951661_2	716544.wcw_0653	1.851e-86	291.0	COG2818@1|root,COG2818@2|Bacteria,2JG0U@204428|Chlamydiae	204428|Chlamydiae	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
LZS2_k127_952940_0	316274.Haur_0944	1.247e-205	651.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,3750V@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
LZS2_k127_952940_1	767817.Desgi_0700	1.597e-21	98.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,260ZV@186807|Peptococcaceae	186801|Clostridia	P	transporter (mgtE)	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS2_k127_956526_0	536232.CLM_2440	7.133e-42	162.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,36E78@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
LZS2_k127_956526_1	110319.CF8_2360	2.145e-20	107.0	COG1652@1|root,COG3170@1|root,COG1652@2|Bacteria,COG3170@2|Bacteria,2I8YV@201174|Actinobacteria,4DRF1@85009|Propionibacteriales	201174|Actinobacteria	NU	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_956526_2	1499967.BAYZ01000009_gene5272	0.0001521	55.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,cNMP_binding
LZS2_k127_971378_1	313606.M23134_00814	2.588e-34	144.0	COG0457@1|root,COG0642@1|root,COG0457@2|Bacteria,COG2205@2|Bacteria	313606.M23134_00814|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_971378_0	506534.Rhein_3488	2.126e-53	196.0	COG3447@1|root,COG5002@1|root,COG3447@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,1X2RK@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,MASE1,PAS_3,PAS_9,Response_reg
LZS2_k127_97713_1	123214.PERMA_1951	1.29e-07	61.0	COG0457@1|root,COG0457@2|Bacteria	123214.PERMA_1951|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_97713_0	330214.NIDE3501	1.111e-34	144.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
LZS2_k127_983171_0	1183438.GKIL_3215	5.668e-107	360.0	COG0260@1|root,COG0260@2|Bacteria,1G079@1117|Cyanobacteria	1117|Cyanobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
LZS2_k127_983171_1	1278073.MYSTI_08088	5.505e-40	165.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,PP2C_2,Pkinase
LZS2_k127_985168_1	484022.Fphi_0080	2.267e-168	537.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,46043@72273|Thiotrichales	72273|Thiotrichales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
LZS2_k127_985168_2	502025.Hoch_2049	9.925e-94	318.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,42PS4@68525|delta/epsilon subdivisions,2WM4V@28221|Deltaproteobacteria,2YUI4@29|Myxococcales	28221|Deltaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
LZS2_k127_985168_0	502025.Hoch_2051	4.997e-203	649.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,42P26@68525|delta/epsilon subdivisions,2WKJ4@28221|Deltaproteobacteria,2YUPH@29|Myxococcales	28221|Deltaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
LZS2_k127_996529_0	1069080.KB913028_gene434	1.728e-81	279.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4H2CB@909932|Negativicutes	909932|Negativicutes	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_996529_1	237368.SCABRO_01668	8.624e-70	243.0	COG3741@1|root,COG3741@2|Bacteria	2|Bacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
LZS2_k127_999570_1	926550.CLDAP_26300	1.606e-59	212.0	COG0503@1|root,COG0503@2|Bacteria,2G71F@200795|Chloroflexi	200795|Chloroflexi	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
LZS2_k127_999570_0	1173021.ALWA01000017_gene2194	4.076e-62	223.0	COG1912@1|root,COG1912@2|Bacteria,1G22D@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
## 3304 queries scanned
## Total time (seconds): 236.83781957626343
## Rate: 13.95 q/s