## Sat Nov 16 14:43:52 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin12/LZS_2_bin.67.fa -m mmseqs --itype genome -o LZS_2_bin.67 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/LZS_2_bin.67 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
LZS2_k127_1009600_7	518766.Rmar_1936	5.616e-85	308.0	COG1186@1|root,COG1186@2|Bacteria,4NJQS@976|Bacteroidetes,1FJSK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
LZS2_k127_1009600_3	105559.Nwat_1587	1.766e-121	398.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1WW1A@135613|Chromatiales	135613|Chromatiales	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
LZS2_k127_1009600_2	1121434.AULY01000006_gene278	4.155e-140	458.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2WKAY@28221|Deltaproteobacteria,2M8IY@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Prokaryotic glutathione synthetase, ATP-grasp domain	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,TrkA_C
LZS2_k127_1009600_11	472759.Nhal_1064	1.719e-55	198.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1WYD4@135613|Chromatiales	135613|Chromatiales	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
LZS2_k127_1009600_0	945713.IALB_2675	2.971e-162	527.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1
LZS2_k127_1009600_1	290397.Adeh_2260	1.387e-157	508.0	COG1143@1|root,COG1143@2|Bacteria,1QYG4@1224|Proteobacteria,43E88@68525|delta/epsilon subdivisions,2X7N9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1009600_8	1500893.JQNB01000001_gene465	3.962e-64	228.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,1X3CK@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_1009600_13	1519464.HY22_12335	2.844e-40	168.0	COG4591@1|root,COG4591@2|Bacteria,1FECJ@1090|Chlorobi	1090|Chlorobi	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_1009600_5	1121875.KB907548_gene1638	1.414e-114	384.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1009600_14	1121875.KB907548_gene1637	5.965e-29	120.0	COG0664@1|root,COG0664@2|Bacteria,4NRPE@976|Bacteroidetes	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
LZS2_k127_1009600_18	1968.JOEV01000008_gene7827	0.0001596	53.0	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GKQG@201174|Actinobacteria	201174|Actinobacteria	DT	Forkhead associated domain	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE,Yop-YscD_cpl
LZS2_k127_1009600_15	1122604.JONR01000019_gene1199	1.299e-11	76.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1X8HM@135614|Xanthomonadales	135614|Xanthomonadales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,Guanylate_cyc
LZS2_k127_1009600_9	886293.Sinac_3059	1.176e-61	222.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11,3.1.4.17	ko:K00784,ko:K01120	ko00230,ko03013,map00230,map03013	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000,ko03016	-	-	-	GAF,HD_5,Lactamase_B_2,PDEase_II
LZS2_k127_1009600_17	1379698.RBG1_1C00001G1816	4.73e-09	68.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
LZS2_k127_1009600_6	195250.CM001776_gene4045	1.704e-97	327.0	COG1215@1|root,COG1215@2|Bacteria,1GMST@1117|Cyanobacteria,1H0CG@1129|Synechococcus	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_1009600_12	312284.A20C1_11496	1.608e-46	184.0	COG2327@1|root,COG2327@2|Bacteria	2|Bacteria	S	slime layer polysaccharide biosynthetic process	-	-	-	ko:K16710	-	-	-	-	ko00000	-	-	-	PS_pyruv_trans
LZS2_k127_1009600_16	1385521.N803_16180	9.267e-10	70.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4FE40@85021|Intrasporangiaceae	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	Glycos_transf_2,LPG_synthase_TM
LZS2_k127_1009600_10	595460.RRSWK_04882	5.269e-57	210.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS2_k127_1009600_4	1408473.JHXO01000008_gene2651	3.159e-119	389.0	COG3408@1|root,COG3408@2|Bacteria,4NGZM@976|Bacteroidetes	976|Bacteroidetes	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100,S6PP
LZS2_k127_1039860_16	909663.KI867151_gene3160	5.489e-25	105.0	COG2197@1|root,COG2197@2|Bacteria,1RARA@1224|Proteobacteria,43B1G@68525|delta/epsilon subdivisions,2X5U5@28221|Deltaproteobacteria,2MRK4@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_1039860_3	269797.Mbar_A0157	5.5e-167	533.0	COG0004@1|root,arCOG04397@2157|Archaea,2XTEB@28890|Euryarchaeota,2N971@224756|Methanomicrobia	224756|Methanomicrobia	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS2_k127_1039860_11	1191523.MROS_2401	8.944e-40	158.0	29A93@1|root,32UVK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
LZS2_k127_1039860_0	472759.Nhal_1482	0.0	1020.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1WZYZ@135613|Chromatiales	135613|Chromatiales	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
LZS2_k127_1039860_6	237368.SCABRO_01060	6.272e-89	295.0	COG2131@1|root,COG2131@2|Bacteria	2|Bacteria	F	dCMP deaminase activity	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
LZS2_k127_1039860_17	203275.BFO_2676	1.644e-05	57.0	2FJRB@1|root,34BE7@2|Bacteria,4P5QR@976|Bacteroidetes,2FYTE@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1039860_13	748449.Halha_0699	8.047e-36	144.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia,3WAS3@53433|Halanaerobiales	186801|Clostridia	S	PFAM MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	ACT,ACT_4,MgtC
LZS2_k127_1039860_12	1254432.SCE1572_51465	1.435e-38	148.0	COG0838@1|root,COG0838@2|Bacteria,1PPP3@1224|Proteobacteria,42VF4@68525|delta/epsilon subdivisions,2WRIV@28221|Deltaproteobacteria,2Z22Z@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
LZS2_k127_1039860_7	1254432.SCE1572_51470	3.763e-68	236.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2Z08H@29|Myxococcales	28221|Deltaproteobacteria	C	Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
LZS2_k127_1039860_10	880073.Calab_2691	6.013e-40	154.0	COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
LZS2_k127_1039860_4	290397.Adeh_2574	1.769e-153	495.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YWJS@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
LZS2_k127_1039860_5	1254432.SCE1572_43755	1.433e-126	416.0	COG0265@1|root,COG1005@1|root,COG0265@2|Bacteria,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2YYND@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh,PDZ_2
LZS2_k127_1039860_9	448385.sce8026	1.325e-44	168.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42SZV@68525|delta/epsilon subdivisions,2WP8T@28221|Deltaproteobacteria,2Z0UI@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4,Fer4_7
LZS2_k127_1039860_14	448385.sce8025	8.683e-36	141.0	COG0839@1|root,COG0839@2|Bacteria,1PJW9@1224|Proteobacteria,42V0F@68525|delta/epsilon subdivisions,2WS8G@28221|Deltaproteobacteria,2Z1CQ@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
LZS2_k127_1039860_15	448385.sce8024	3.022e-26	113.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42WIQ@68525|delta/epsilon subdivisions,2WS3A@28221|Deltaproteobacteria,2Z1V8@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
LZS2_k127_1039860_1	1125863.JAFN01000001_gene2410	1.098e-209	673.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
LZS2_k127_1039860_2	880073.Calab_2684	1.263e-200	636.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
LZS2_k127_1039860_8	340177.Cag_0644	2.443e-51	190.0	COG1007@1|root,COG1007@2|Bacteria,1FDDP@1090|Chlorobi	1090|Chlorobi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS2_k127_1166261_7	768710.DesyoDRAFT_1744	2.895e-12	71.0	COG0183@1|root,COG0183@2|Bacteria,1UZXX@1239|Firmicutes,249SJ@186801|Clostridia,2610E@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_1166261_4	1379698.RBG1_1C00001G0893	5.408e-49	184.0	COG1309@1|root,COG1309@2|Bacteria,2NS0M@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
LZS2_k127_1166261_3	767817.Desgi_3838	2.481e-175	556.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
LZS2_k127_1166261_0	1121405.dsmv_2380	0.0	1137.0	COG2414@1|root,COG2414@2|Bacteria,1R955@1224|Proteobacteria,42NN4@68525|delta/epsilon subdivisions,2WJEQ@28221|Deltaproteobacteria,2MMX0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	bamB-2	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
LZS2_k127_1166261_5	1232410.KI421423_gene1923	3.883e-48	181.0	COG1142@1|root,COG1142@2|Bacteria,1RBG7@1224|Proteobacteria,42R5G@68525|delta/epsilon subdivisions,2WMV5@28221|Deltaproteobacteria,43U2T@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K19516	ko00362,ko01100,ko01120,map00362,map01100,map01120	M00541	R10961	RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	-
LZS2_k127_1166261_2	1121405.dsmv_2374	6.171e-180	572.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MJHX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	bamD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
LZS2_k127_1166261_6	56780.SYN_01644	8.901e-27	111.0	COG1148@1|root,COG1148@2|Bacteria,1P24T@1224|Proteobacteria,431A0@68525|delta/epsilon subdivisions,2WWJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
LZS2_k127_1166261_1	706587.Desti_1915	0.0	1073.0	COG1148@1|root,COG1149@1|root,COG1148@2|Bacteria,COG1149@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MQTI@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
LZS2_k127_1186518_3	1379698.RBG1_1C00001G1562	9.058e-48	178.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
LZS2_k127_1186518_0	452637.Oter_1625	1.764e-115	387.0	COG0213@1|root,COG0213@2|Bacteria,46TE4@74201|Verrucomicrobia,3K932@414999|Opitutae	414999|Opitutae	F	PFAM glycosyl transferase family 3	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
LZS2_k127_1186518_2	1089551.KE386572_gene1993	2.515e-52	193.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,2TS26@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
LZS2_k127_1186518_4	264732.Moth_0599	7.829e-28	118.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,42GSG@68295|Thermoanaerobacterales	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
LZS2_k127_1186518_1	1499689.CCNN01000007_gene948	3.747e-58	206.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,36E24@31979|Clostridiaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
LZS2_k127_1237195_0	1123371.ATXH01000013_gene1505	1.342e-213	678.0	COG0441@1|root,COG0441@2|Bacteria,2GH53@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
LZS2_k127_1237195_3	1379698.RBG1_1C00001G1116	3.465e-55	201.0	COG0290@1|root,COG0290@2|Bacteria,2NPDH@2323|unclassified Bacteria	2|Bacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
LZS2_k127_1237195_5	1392493.JIAB01000001_gene2595	1.971e-16	82.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,27PJB@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
LZS2_k127_1237195_4	696369.KI912183_gene906	3.729e-42	157.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,2627I@186807|Peptococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
LZS2_k127_1237195_1	273068.TTE1689	9.597e-125	408.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,42EPG@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
LZS2_k127_1237195_2	572544.Ilyop_0012	3.494e-118	396.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,378F8@32066|Fusobacteria	32066|Fusobacteria	J	Phenylalanyl-tRNA synthetase beta	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
LZS2_k127_1242492_5	1123070.KB899253_gene1038	6.771e-67	251.0	COG0457@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3379@2|Bacteria,46URB@74201|Verrucomicrobia,2IV4Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_1242492_1	768704.Desmer_4497	1.604e-178	572.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,2602C@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
LZS2_k127_1242492_12	1280390.CBQR020000151_gene4031	2.373e-05	56.0	COG1807@1|root,COG1807@2|Bacteria,1UYMG@1239|Firmicutes,4HB8M@91061|Bacilli,26ZKF@186822|Paenibacillaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_1242492_4	234267.Acid_0283	4.223e-121	398.0	COG0399@1|root,COG0399@2|Bacteria,3Y3PT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_1242492_3	1379698.RBG1_1C00001G0505	1.614e-126	440.0	COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
LZS2_k127_1242492_13	203275.BFO_0745	0.0009857	51.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,2FP81@200643|Bacteroidia,22WNK@171551|Porphyromonadaceae	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
LZS2_k127_1242492_7	1480694.DC28_10460	5.829e-31	124.0	COG0347@1|root,COG0347@2|Bacteria,2J85W@203691|Spirochaetes	203691|Spirochaetes	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1242492_9	933262.AXAM01000014_gene262	1.821e-20	105.0	COG0025@1|root,COG0025@2|Bacteria,1N7PG@1224|Proteobacteria,42V45@68525|delta/epsilon subdivisions,2WRJ6@28221|Deltaproteobacteria,2MN9H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1242492_6	933262.AXAM01000014_gene261	9.745e-63	233.0	COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,42RF1@68525|delta/epsilon subdivisions,2WMJJ@28221|Deltaproteobacteria,2MJ88@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,PTS_EIIA_2,TrkA_C,TrkA_N
LZS2_k127_1242492_8	439235.Dalk_4220	3.709e-26	121.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria,2MNGQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
LZS2_k127_1242492_0	742817.HMPREF9449_02474	5.873e-196	617.0	COG0205@1|root,COG0205@2|Bacteria,4NFPT@976|Bacteroidetes,2FMJ9@200643|Bacteroidia,22ZT1@171551|Porphyromonadaceae	976|Bacteroidetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS2_k127_1242492_2	1122176.KB903537_gene1611	8.796e-143	465.0	COG0668@1|root,COG0668@2|Bacteria,4NE4R@976|Bacteroidetes,1IRR2@117747|Sphingobacteriia	976|Bacteroidetes	M	mechanosensitive ion channel protein MscS	mscS	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
LZS2_k127_1242492_11	264732.Moth_0241	4.585e-12	78.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Calx-beta,DUF11,DUF1573,F5_F8_type_C,FG-GAP,Glyco_hyd_101C,Glyco_hydro_101,NPCBM_assoc,SASA
LZS2_k127_1242492_10	880073.Calab_0272	1.037e-16	92.0	COG1649@1|root,COG3023@1|root,COG3391@1|root,COG4412@1|root,COG1649@2|Bacteria,COG3023@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.20,3.4.17.22,3.5.1.28	ko:K01187,ko:K01448,ko:K07752	ko00052,ko00500,ko01100,ko01503,map00052,map00500,map01100,map01503	M00727	R00028,R00801,R00802,R04112,R06087,R06088	RC00028,RC00049,RC00064,RC00077,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036	-	GH31	-	Amidase_2
LZS2_k127_1252909_0	1125779.HMPREF1219_01784	2.723e-66	229.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,22KK5@1653|Corynebacteriaceae	201174|Actinobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
LZS2_k127_1252909_2	1236514.BAKL01000085_gene4857	4.403e-05	56.0	COG1874@1|root,COG1874@2|Bacteria,4NEFS@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Glyco_hydro_42
LZS2_k127_1252909_1	1089553.Tph_c09140	1.501e-17	87.0	COG1959@1|root,COG1959@2|Bacteria,1UT43@1239|Firmicutes,2518T@186801|Clostridia,42ID9@68295|Thermoanaerobacterales	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS2_k127_1253409_7	1303518.CCALI_02008	1.144e-13	77.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
LZS2_k127_1253409_2	269799.Gmet_0138	4.86e-130	435.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
LZS2_k127_1253409_6	1379698.RBG1_1C00001G1012	1.056e-13	76.0	COG1314@1|root,COG1314@2|Bacteria,2NQ7S@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase SecG subunit	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
LZS2_k127_1253409_3	370438.PTH_2721	6.862e-81	276.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
LZS2_k127_1253409_0	945713.IALB_1271	9.287e-147	475.0	COG0126@1|root,COG0126@2|Bacteria	2|Bacteria	F	phosphoglycerate kinase activity	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
LZS2_k127_1253409_1	880073.Calab_3781	1.652e-139	450.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
LZS2_k127_1253409_8	1005995.GTPT_0434	9.967e-10	69.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,4BUYP@82986|Tatumella	1236|Gammaproteobacteria	S	Competence protein	gntX	GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	Pribosyltran
LZS2_k127_1253409_4	1379698.RBG1_1C00001G1006	8.478e-49	184.0	COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria	2|Bacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS2_k127_1253409_5	1379698.RBG1_1C00001G1004	2.72e-41	155.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
LZS2_k127_1276638_15	383372.Rcas_3213	3.182e-19	99.0	COG0392@1|root,COG0392@2|Bacteria,2GADT@200795|Chloroflexi,375NR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_1276638_18	340.xcc-b100_1909	1.024e-07	64.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1X4AM@135614|Xanthomonadales	135614|Xanthomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
LZS2_k127_1276638_6	1121468.AUBR01000005_gene69	1.966e-70	254.0	COG1035@1|root,COG1145@1|root,COG1035@2|Bacteria,COG1145@2|Bacteria,1TQGA@1239|Firmicutes,249BE@186801|Clostridia,42HGQ@68295|Thermoanaerobacterales	186801|Clostridia	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,FrhB_FdhB_C,FrhB_FdhB_N,PS_pyruv_trans
LZS2_k127_1276638_19	351160.RRC424	0.0008896	52.0	COG5427@1|root,arCOG00563@2157|Archaea	2157|Archaea	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
LZS2_k127_1276638_3	871968.DESME_08305	3.536e-149	485.0	COG0591@1|root,COG0591@2|Bacteria,1TQEZ@1239|Firmicutes,24AJN@186801|Clostridia,262IJ@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS2_k127_1276638_1	909663.KI867150_gene381	3.283e-194	628.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MRD4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
LZS2_k127_1276638_5	1121405.dsmv_2843	2.756e-81	280.0	COG1924@1|root,COG1924@2|Bacteria,1RDZA@1224|Proteobacteria,42RYS@68525|delta/epsilon subdivisions,2WNJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	TIGRFAM CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
LZS2_k127_1276638_2	706587.Desti_1564	7.408e-179	570.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
LZS2_k127_1276638_17	1298920.KI911353_gene805	2.28e-09	70.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,2218U@1506553|Lachnoclostridium	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1276638_16	562970.Btus_2626	7.859e-19	100.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,4HDWZ@91061|Bacilli,278P4@186823|Alicyclobacillaceae	91061|Bacilli	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS2_k127_1276638_12	457570.Nther_2211	1.235e-48	190.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
LZS2_k127_1276638_9	926550.CLDAP_11640	4.14e-64	233.0	COG3608@1|root,COG3608@2|Bacteria,2G71G@200795|Chloroflexi	200795|Chloroflexi	S	succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	-
LZS2_k127_1276638_11	767817.Desgi_1592	5.055e-51	192.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,264MQ@186807|Peptococcaceae	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS2_k127_1276638_13	742733.HMPREF9469_01315	3.706e-45	189.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,220IW@1506553|Lachnoclostridium	186801|Clostridia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
LZS2_k127_1276638_0	767817.Desgi_3972	9.582e-238	769.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,264EG@186807|Peptococcaceae	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS2_k127_1276638_8	1232410.KI421419_gene2452	8.002e-65	233.0	COG1893@1|root,COG1893@2|Bacteria,1R96Z@1224|Proteobacteria,42PU0@68525|delta/epsilon subdivisions,2WK47@28221|Deltaproteobacteria,43SYC@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS2_k127_1276638_4	479434.Sthe_3301	1.653e-142	463.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,27YZQ@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS2_k127_1276638_14	717785.HYPMC_4055	1.186e-22	104.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2TV2G@28211|Alphaproteobacteria,3N7CZ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS2_k127_1276638_20	1123376.AUIU01000019_gene1248	0.0009325	46.0	COG1763@1|root,COG1763@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	ko:K03753,ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	-
LZS2_k127_1276638_7	1408473.JHXO01000010_gene3618	7.112e-68	247.0	COG0303@1|root,COG0303@2|Bacteria,4NDYD@976|Bacteroidetes	976|Bacteroidetes	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS2_k127_1276638_10	42565.FP66_16075	9.894e-52	187.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1XHTC@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
LZS2_k127_1402010_0	247490.KSU1_C0842	2.879e-148	492.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Cofac_haem_bdg,PDZ_2,Peptidase_M1,Peptidase_M28
LZS2_k127_1402010_3	1279009.ADICEAN_00555	0.0006668	52.0	COG0457@1|root,COG0457@2|Bacteria,4PM6F@976|Bacteroidetes,47Y4H@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
LZS2_k127_1402010_1	1379698.RBG1_1C00001G0231	4.622e-26	124.0	COG1413@1|root,COG1413@2|Bacteria,2NRMK@2323|unclassified Bacteria	2|Bacteria	C	HEAT repeats	CP_0755	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Response_reg
LZS2_k127_1424832_0	1379698.RBG1_1C00001G1217	1.765e-149	486.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2NP05@2323|unclassified Bacteria	2|Bacteria	H	Methylenetetrahydrofolate reductase	yitJ	-	1.5.1.20,2.1.1.10,2.1.1.13	ko:K00297,ko:K00547,ko:K00548	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523	M00017,M00377	R00650,R00946,R01224,R07168,R09365	RC00003,RC00035,RC00081,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
LZS2_k127_1454807_2	1047013.AQSP01000091_gene641	9.81e-43	167.0	COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
LZS2_k127_1454807_4	909663.KI867150_gene887	4.035e-06	51.0	299YV@1|root,2ZX0J@2|Bacteria,1P75H@1224|Proteobacteria,432SS@68525|delta/epsilon subdivisions,2WY0Q@28221|Deltaproteobacteria,2MSEU@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1454807_0	909663.KI867150_gene971	2.331e-181	580.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X1VS@28221|Deltaproteobacteria,2MRES@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_1454807_1	909663.KI867150_gene970	2.631e-115	393.0	COG4191@1|root,COG4191@2|Bacteria,1R89N@1224|Proteobacteria,42QDX@68525|delta/epsilon subdivisions,2WKNA@28221|Deltaproteobacteria,2MR83@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
LZS2_k127_1454807_3	420324.KI911956_gene3487	4.255e-42	158.0	COG0216@1|root,COG0216@2|Bacteria,1R348@1224|Proteobacteria,2TZXT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
LZS2_k127_1455417_1	485915.Dret_0882	0.000404	47.0	2DD8W@1|root,2ZH3F@2|Bacteria,1PBGJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1455417_0	880073.Calab_2508	4.136e-213	672.0	COG2866@1|root,COG2866@2|Bacteria,2NQNH@2323|unclassified Bacteria	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
LZS2_k127_1457756_5	1123405.AUMM01000004_gene730	2.174e-66	230.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,26NI3@186821|Sporolactobacillaceae	91061|Bacilli	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
LZS2_k127_1457756_8	648996.Theam_1218	1.1e-44	166.0	COG0698@1|root,COG0698@2|Bacteria,2G43P@200783|Aquificae	200783|Aquificae	G	ribose 5-phosphate isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
LZS2_k127_1457756_0	234267.Acid_5573	2.163e-138	446.0	COG0115@1|root,COG0115@2|Bacteria,3Y32X@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS2_k127_1457756_10	697281.Mahau_0044	2.441e-27	117.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS2_k127_1457756_4	387631.Asulf_01626	1.278e-71	257.0	COG0644@1|root,arCOG00570@2157|Archaea,2XU3J@28890|Euryarchaeota,245QU@183980|Archaeoglobi	183980|Archaeoglobi	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
LZS2_k127_1457756_12	1136417.AZWE01000006_gene4358	0.0001707	49.0	COG1149@1|root,COG1149@2|Bacteria,2IMA0@201174|Actinobacteria,4DJRJ@85008|Micromonosporales	201174|Actinobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_21,Fer4_4
LZS2_k127_1457756_1	1232410.KI421427_gene1286	7.97e-110	373.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,43RYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
LZS2_k127_1457756_3	1121403.AUCV01000032_gene2908	1.468e-81	284.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,42R2C@68525|delta/epsilon subdivisions,2WMZ7@28221|Deltaproteobacteria,2MKAM@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_1457756_9	75379.Tint_1509	1.527e-29	128.0	COG0726@1|root,COG0726@2|Bacteria,1N53V@1224|Proteobacteria,2VWYF@28216|Betaproteobacteria,1KMQR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS2_k127_1457756_2	448385.sce8918	6.61e-85	294.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2YXW5@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_1457756_6	935863.AWZR01000003_gene2844	5.524e-57	216.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,1RZBT@1236|Gammaproteobacteria,1X3JT@135614|Xanthomonadales	135614|Xanthomonadales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_1457756_11	357808.RoseRS_0400	2.249e-24	112.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
LZS2_k127_1457756_7	762984.HMPREF9445_01450	1.934e-48	198.0	COG5652@1|root,COG5652@2|Bacteria,4NIE7@976|Bacteroidetes,2FNFY@200643|Bacteroidia,4ANF6@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4962)	-	GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510	4.2.2.7,4.2.2.8	ko:K19051	-	-	-	-	ko00000,ko01000	-	PL21	-	DUF4962,Hepar_II_III
LZS2_k127_14704_0	1125863.JAFN01000001_gene929	1.201e-207	663.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS2_k127_1602527_2	1121459.AQXE01000002_gene1358	3.323e-10	74.0	COG0296@1|root,COG0296@2|Bacteria,1NEFK@1224|Proteobacteria,42VRH@68525|delta/epsilon subdivisions,2WRD5@28221|Deltaproteobacteria,2MC6U@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
LZS2_k127_1602527_1	1382359.JIAL01000001_gene1569	1.753e-84	287.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
LZS2_k127_1602527_0	945713.IALB_1779	7.269e-160	512.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	gcdH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_1613186_2	748449.Halha_1418	2.991e-45	166.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WB8I@53433|Halanaerobiales	186801|Clostridia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS2_k127_1613186_3	1123368.AUIS01000009_gene2482	4.156e-24	103.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,2ND6R@225057|Acidithiobacillales	225057|Acidithiobacillales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS2_k127_1613186_0	1121121.KB894290_gene1866	9.275e-165	528.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,26QJA@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS2_k127_1613186_1	1379698.RBG1_1C00001G1823	4.409e-53	196.0	COG0571@1|root,COG0571@2|Bacteria,2NPCJ@2323|unclassified Bacteria	2|Bacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
LZS2_k127_1647354_2	1382358.JHVN01000010_gene1540	6.799e-35	145.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,4H9T5@91061|Bacilli,21WMH@150247|Anoxybacillus	91061|Bacilli	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS2_k127_1647354_1	795359.TOPB45_0864	1.947e-75	266.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
LZS2_k127_1647354_0	795359.TOPB45_0865	1.742e-82	303.0	COG0419@1|root,COG0419@2|Bacteria,2GI5T@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	-
LZS2_k127_1647354_3	706434.HMPREF9429_00732	3.777e-29	133.0	COG1807@1|root,COG1807@2|Bacteria,1UY16@1239|Firmicutes,4H35V@909932|Negativicutes	909932|Negativicutes	M	dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,SNARE_assoc
LZS2_k127_1648311_5	997829.HMPREF1121_00081	4.558e-06	59.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,2FQBP@200643|Bacteroidia	976|Bacteroidetes	L	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
LZS2_k127_1648311_3	1121377.KB906406_gene162	1.093e-13	84.0	COG2374@1|root,COG4085@1|root,COG2374@2|Bacteria,COG4085@2|Bacteria	2|Bacteria	S	PFAM nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Big_3_5,Big_5,Endonuclease_1,LTD
LZS2_k127_1648311_1	1123278.KB893388_gene5637	8.332e-33	147.0	COG2304@1|root,COG2304@2|Bacteria,4NER3@976|Bacteroidetes,47JA7@768503|Cytophagia	976|Bacteroidetes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1648311_0	880073.Calab_0680	1.408e-35	139.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS2_k127_1648311_2	880073.Calab_0680	4.516e-28	119.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS2_k127_1648311_4	880073.Calab_0686	1.691e-06	51.0	COG0457@1|root,COG0457@2|Bacteria,2NRRK@2323|unclassified Bacteria	2|Bacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1725256_1	269797.Mbar_A2759	1.442e-26	124.0	COG0265@1|root,arCOG02833@2157|Archaea	2157|Archaea	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
LZS2_k127_1725256_0	204669.Acid345_0604	3.055e-105	371.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_1736501_1	1163617.SCD_n01357	2.352e-35	147.0	COG5660@1|root,32WII@2|Bacteria,1R3ME@1224|Proteobacteria	1224|Proteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
LZS2_k127_1736501_0	246197.MXAN_4147	1.815e-46	175.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_1736501_2	765912.Thimo_2458	4.281e-07	61.0	COG5662@1|root,COG5662@2|Bacteria,1MV95@1224|Proteobacteria,1SFJZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS2_k127_1769059_6	665942.HMPREF1022_00855	2.809e-18	87.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MCGN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
LZS2_k127_1769059_4	290512.Paes_1016	3.595e-20	98.0	COG0806@1|root,COG0806@2|Bacteria,1FE5Z@1090|Chlorobi	1090|Chlorobi	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
LZS2_k127_1769059_1	1122129.AUEF01000001_gene958	6.43e-69	240.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,4GY5I@90964|Staphylococcaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
LZS2_k127_1769059_3	1385513.N780_10835	2.822e-36	144.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,2YAG5@289201|Pontibacillus	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
LZS2_k127_1769059_2	1196029.ALIM01000014_gene3270	3.53e-46	175.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,1ZB7H@1386|Bacillus	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS2_k127_1769059_5	1249975.JQLP01000005_gene2616	5.007e-19	91.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1I49T@117743|Flavobacteriia,2P6XW@244698|Gillisia	976|Bacteroidetes	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
LZS2_k127_1769059_7	1007103.AFHW01000016_gene5969	1.518e-06	58.0	COG4632@1|root,COG4632@2|Bacteria,1UYWQ@1239|Firmicutes,4HDXQ@91061|Bacilli,26WD4@186822|Paenibacillaceae	91061|Bacilli	G	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
LZS2_k127_1769059_0	443143.GM18_0801	7.763e-171	557.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
LZS2_k127_177792_4	880073.Calab_2910	6.472e-63	221.0	COG0168@1|root,COG0168@2|Bacteria,2NQH8@2323|unclassified Bacteria	2|Bacteria	P	Cation transport protein	trkH	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662	-	ko:K03498,ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	iECDH1ME8569_1439.ECDH1ME8569_1308,iPC815.YPO3762,iSFV_1184.SFV_3651	TrkH
LZS2_k127_177792_3	935948.KE386495_gene2050	2.361e-65	228.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,24DYE@186801|Clostridia,42FWT@68295|Thermoanaerobacterales	186801|Clostridia	C	Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS2_k127_177792_2	43989.cce_1643	1.299e-70	248.0	COG0778@1|root,COG0778@2|Bacteria,1G42X@1117|Cyanobacteria,3KJXS@43988|Cyanothece	1117|Cyanobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS2_k127_177792_0	204669.Acid345_0166	2.158e-213	674.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
LZS2_k127_177792_1	588596.U9SKP0	6.692e-122	405.0	COG0334@1|root,KOG2250@2759|Eukaryota,39VR7@33154|Opisthokonta,3P7DY@4751|Fungi	4751|Fungi	E	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_177792_5	1519464.HY22_04230	3.762e-50	185.0	COG0242@1|root,COG0242@2|Bacteria	2|Bacteria	J	peptide deformylase activity	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	HTH_31,Pep_deformylase
LZS2_k127_1833642_3	743720.Psefu_0193	3.983e-16	85.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1YX5T@136845|Pseudomonas putida group	1236|Gammaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS2_k127_1833642_1	485913.Krac_1563	3.623e-46	188.0	COG1520@1|root,COG1520@2|Bacteria,2GBGD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS2_k127_1833642_2	1231336.L248_1474	4.665e-18	89.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3F7FW@33958|Lactobacillaceae	91061|Bacilli	K	Cold shock protein	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS2_k127_1833642_0	1379698.RBG1_1C00001G1656	0.0	1014.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
LZS2_k127_186906_19	138119.DSY3330	1.144e-28	125.0	COG0860@1|root,COG2247@1|root,COG0860@2|Bacteria,COG2247@2|Bacteria,1V6BP@1239|Firmicutes,25B61@186801|Clostridia,264HP@186807|Peptococcaceae	186801|Clostridia	M	cell wall binding repeat 2	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,CW_binding_2
LZS2_k127_186906_10	1121430.JMLG01000005_gene718	1.489e-95	331.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,2608U@186807|Peptococcaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
LZS2_k127_186906_25	1121456.ATVA01000014_gene756	2.89e-05	57.0	COG0457@1|root,COG3147@1|root,COG0457@2|Bacteria,COG3147@2|Bacteria,1PDTX@1224|Proteobacteria,42RK5@68525|delta/epsilon subdivisions,2WNZC@28221|Deltaproteobacteria,2M93P@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
LZS2_k127_186906_1	1379698.RBG1_1C00001G1432	2.482e-156	536.0	COG1196@1|root,COG1196@2|Bacteria,2NNYZ@2323|unclassified Bacteria	2|Bacteria	D	Required for chromosome condensation and partitioning	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529,ko:K19171	-	-	-	-	ko00000,ko02048,ko03036	-	-	-	SMC_N,SMC_hinge
LZS2_k127_186906_13	394503.Ccel_0697	1.596e-81	280.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,36EQQ@31979|Clostridiaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
LZS2_k127_186906_26	1197719.A464_3227	0.0004082	44.0	2EU99@1|root,33MRP@2|Bacteria,1NPIK@1224|Proteobacteria,1SHD7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_186906_14	1123239.KB898624_gene1755	2.274e-74	264.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,4HBNA@91061|Bacilli	91061|Bacilli	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
LZS2_k127_186906_17	562970.Btus_1825	6.69e-42	161.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4HC7B@91061|Bacilli,278YZ@186823|Alicyclobacillaceae	91061|Bacilli	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08950,iYO844.BSU23270	Lum_binding
LZS2_k127_186906_0	264732.Moth_0917	1.505e-165	529.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,42FC2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
LZS2_k127_186906_16	862908.BMS_0016	3.47e-49	179.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2MUDA@213481|Bdellovibrionales,2WNCZ@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
LZS2_k127_186906_20	289376.THEYE_A1848	9.406e-24	106.0	COG0781@1|root,COG0781@2|Bacteria,3J0RV@40117|Nitrospirae	40117|Nitrospirae	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
LZS2_k127_186906_15	59374.Fisuc_0695	9.665e-57	207.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
LZS2_k127_186906_7	1379698.RBG1_1C00001G1319	1.017e-100	340.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_186906_18	59374.Fisuc_0693	2.321e-35	148.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_186906_4	1379698.RBG1_1C00001G0356	4.263e-120	416.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
LZS2_k127_186906_6	656519.Halsa_0583	3.139e-107	356.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,3WB5Q@53433|Halanaerobiales	186801|Clostridia	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS2_k127_186906_9	1191523.MROS_1306	1.634e-97	329.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS2_k127_186906_8	419665.Maeo_0395	2.464e-98	333.0	COG0438@1|root,arCOG01415@2157|Archaea,2XUVW@28890|Euryarchaeota,23R82@183939|Methanococci	183939|Methanococci	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_186906_11	324925.Ppha_0260	9.442e-92	332.0	COG5617@1|root,COG5617@2|Bacteria,1FDV6@1090|Chlorobi	1090|Chlorobi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS2_k127_186906_12	1379698.RBG1_1C00001G0996	5.215e-90	306.0	COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS2_k127_186906_2	1499967.BAYZ01000063_gene6022	2.219e-132	450.0	COG1216@1|root,COG2148@1|root,COG1216@2|Bacteria,COG2148@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K03606,ko:K07011	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_186906_23	1237149.C900_02407	6.127e-15	89.0	COG3292@1|root,COG3883@1|root,COG4251@1|root,COG3292@2|Bacteria,COG3883@2|Bacteria,COG4251@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,Reg_prop,Y_Y_Y
LZS2_k127_186906_24	1185876.BN8_05830	2.23e-10	74.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,47M4V@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
LZS2_k127_186906_3	1123386.AUIW01000007_gene1593	5.188e-131	433.0	COG1086@1|root,COG1086@2|Bacteria,1WIQA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
LZS2_k127_186906_5	768706.Desor_5325	1.124e-118	394.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,261AB@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	spsC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_186906_21	68199.JNZO01000031_gene2971	8.909e-22	106.0	COG5653@1|root,COG5653@2|Bacteria,2IKIG@201174|Actinobacteria	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
LZS2_k127_186906_22	1519464.HY22_06365	8.83e-17	85.0	COG0438@1|root,COG0438@2|Bacteria,1FE81@1090|Chlorobi	1090|Chlorobi	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
LZS2_k127_1942614_1	1232410.KI421424_gene1754	9.978e-128	426.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria,43TAB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
LZS2_k127_1942614_5	96561.Dole_2249	7.938e-49	186.0	2E0M7@1|root,32W6F@2|Bacteria,1NB9Z@1224|Proteobacteria,42W6T@68525|delta/epsilon subdivisions,2WSFF@28221|Deltaproteobacteria,2MNT8@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_1942614_4	1499967.BAYZ01000048_gene2693	1.366e-76	272.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	-	-	-	ko:K15738,ko:K18231	ko02010,map02010	-	-	-	br01600,ko00000,ko00001,ko01504,ko02000	3.A.1.120.6,3.A.1.121.1,3.A.1.121.3	-	-	ABC_tran
LZS2_k127_1942614_7	1304874.JAFY01000002_gene125	2.575e-20	94.0	COG0488@1|root,COG0488@2|Bacteria,3TC1K@508458|Synergistetes	508458|Synergistetes	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS2_k127_1942614_9	880073.Calab_3215	6.51e-07	59.0	COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 70	-	-	3.1.11.2,3.2.1.1	ko:K01142,ko:K01176	ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000,ko03400	-	GH13	-	Alpha-amylase,CBM_25,DUF1939,He_PIG
LZS2_k127_1942614_11	709991.Odosp_1222	2.919e-06	57.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NEIE@976|Bacteroidetes,2FMGF@200643|Bacteroidia,22X3J@171551|Porphyromonadaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,OMP_b-brl_3,Plug,TonB_dep_Rec
LZS2_k127_1942614_14	765912.Thimo_1752	0.000456	53.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,1RZ6G@1236|Gammaproteobacteria,1X1H2@135613|Chromatiales	135613|Chromatiales	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
LZS2_k127_1942614_13	1379698.RBG1_1C00001G1616	0.0003987	44.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS2_k127_1942614_12	518766.Rmar_1071	1.757e-05	58.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
LZS2_k127_1942614_8	243090.RB3075	1.929e-12	81.0	2EYTK@1|root,33S0U@2|Bacteria,2IYA9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1
LZS2_k127_1942614_2	519989.ECTPHS_10481	2.499e-94	331.0	COG1538@1|root,COG1538@2|Bacteria,1R705@1224|Proteobacteria,1S0X1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS2_k127_1942614_0	690850.Desaf_3621	0.0	1145.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_1942614_3	1499967.BAYZ01000151_gene1667	9.787e-84	292.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
LZS2_k127_1942614_6	1122176.KB903565_gene3379	1.349e-43	178.0	COG2304@1|root,COG2304@2|Bacteria,4PKD0@976|Bacteroidetes,1IXV1@117747|Sphingobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,LRR_adjacent
LZS2_k127_1969307_3	324925.Ppha_2251	3.294e-55	201.0	COG0613@1|root,COG0613@2|Bacteria,1FDKZ@1090|Chlorobi	1090|Chlorobi	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
LZS2_k127_1969307_1	1379698.RBG1_1C00001G1873	1.311e-112	374.0	COG0379@1|root,COG0379@2|Bacteria,2NP47@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
LZS2_k127_1969307_7	243233.MCA0664	7.985e-07	54.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XF8T@135618|Methylococcales	135618|Methylococcales	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS2_k127_1969307_4	192952.MM_0826	2.65e-36	148.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,2N96I@224756|Methanomicrobia	224756|Methanomicrobia	H	PFAM bifunctional deaminase-reductase domain protein	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
LZS2_k127_1969307_0	237368.SCABRO_01193	7.416e-152	499.0	COG0674@1|root,COG0674@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
LZS2_k127_1969307_2	1307761.L21SP2_2797	5.407e-83	284.0	COG1013@1|root,COG1013@2|Bacteria,2J6R4@203691|Spirochaetes	203691|Spirochaetes	C	oxidoreductase beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
LZS2_k127_1969307_6	237368.SCABRO_03616	4.871e-14	78.0	COG2210@1|root,COG2210@2|Bacteria,2J3DW@203682|Planctomycetes	203682|Planctomycetes	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
LZS2_k127_2006636_1	880072.Desac_1620	2.193e-149	486.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MQYU@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
LZS2_k127_2006636_0	331678.Cphamn1_1855	5.967e-173	559.0	COG0493@1|root,COG0493@2|Bacteria,1FDFY@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2
LZS2_k127_2006636_3	1121428.DESHY_10149___1	5.157e-42	169.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,2625C@186807|Peptococcaceae	186801|Clostridia	H	TIGRFAM siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
LZS2_k127_2006636_2	883.DvMF_2767	1.039e-69	244.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2M9KC@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
LZS2_k127_2006636_5	666510.ASAC_1286	5.813e-05	54.0	arCOG00022@1|root,arCOG00022@2157|Archaea,2XQTH@28889|Crenarchaeota	28889|Crenarchaeota	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS2_k127_2051107_0	926560.KE387025_gene3969	4.87e-262	829.0	COG2217@1|root,COG2217@2|Bacteria,1WJ55@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS2_k127_2051107_1	335543.Sfum_0412	5.184e-74	259.0	COG1575@1|root,COG1575@2|Bacteria,1PWVZ@1224|Proteobacteria,4349B@68525|delta/epsilon subdivisions,2X2PW@28221|Deltaproteobacteria,2MRJX@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS2_k127_2051107_2	595460.RRSWK_04778	6.416e-29	136.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8
LZS2_k127_210112_7	1379698.RBG1_1C00001G1143	2.36e-32	128.0	COG0776@1|root,COG0776@2|Bacteria,2NPU6@2323|unclassified Bacteria	2|Bacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup_1	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS2_k127_210112_1	266117.Rxyl_0796	5.256e-102	342.0	COG2008@1|root,COG2008@2|Bacteria,2GJ0V@201174|Actinobacteria,4CPJX@84995|Rubrobacteria	84995|Rubrobacteria	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS2_k127_210112_2	1122981.AUME01000037_gene1352	3.138e-67	237.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,2FMU1@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
LZS2_k127_210112_8	357808.RoseRS_0118	1.774e-31	130.0	COG0558@1|root,COG0558@2|Bacteria,2G9UJ@200795|Chloroflexi,377IH@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS2_k127_210112_5	1131462.DCF50_p881	9.297e-36	144.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,2624N@186807|Peptococcaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS2_k127_210112_3	1249627.D779_1180	4.999e-52	204.0	COG2208@1|root,COG2770@1|root,COG2208@2|Bacteria,COG2770@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,1WXGP@135613|Chromatiales	135613|Chromatiales	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K01079,ko:K07315	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	GAF,HAMP,SpoIIE,dCache_1
LZS2_k127_210112_0	459349.CLOAM0355	1.457e-116	394.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS2_k127_210112_4	1191523.MROS_1840	7.377e-47	176.0	COG4359@1|root,COG4359@2|Bacteria	2|Bacteria	E	L-methionine salvage from methylthioadenosine	mtnX	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	HAD,Put_Phosphatase
LZS2_k127_210112_6	1341151.ASZU01000006_gene2798	4.83e-35	147.0	COG1073@1|root,COG1073@2|Bacteria,1V1RV@1239|Firmicutes,4HGDR@91061|Bacilli,27B3I@186824|Thermoactinomycetaceae	91061|Bacilli	S	alpha/beta hydrolase fold	M1-904	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
LZS2_k127_210112_9	471857.Svir_37590	3.626e-14	76.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria,4DZKY@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090	-	-	-	-	-	-	-	-	-	-	Dus
LZS2_k127_2107665_8	344747.PM8797T_12653	5.649e-12	73.0	COG2839@1|root,COG2839@2|Bacteria,2J1KN@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
LZS2_k127_2107665_3	1232410.KI421418_gene2299	1.162e-79	276.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	SecD/SecF GG Motif	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS2_k127_2107665_0	880073.Calab_0027	1.326e-120	408.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS2_k127_2107665_2	1158318.ATXC01000001_gene465	8.135e-82	278.0	COG0854@1|root,COG0854@2|Bacteria,2G3M8@200783|Aquificae	200783|Aquificae	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
LZS2_k127_2107665_4	1120985.AUMI01000014_gene930	1.347e-48	188.0	COG2861@1|root,COG2861@2|Bacteria,1V413@1239|Firmicutes,4H49M@909932|Negativicutes	909932|Negativicutes	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
LZS2_k127_2107665_7	518766.Rmar_0713	1.601e-13	78.0	2EGU2@1|root,33AK8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2107665_5	335543.Sfum_3312	1.386e-41	165.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,2MQIS@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
LZS2_k127_2107665_6	290512.Paes_0960	4.975e-23	105.0	COG4194@1|root,COG4194@2|Bacteria,1FF6D@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
LZS2_k127_2107665_1	1499967.BAYZ01000097_gene4328	3.047e-98	330.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	ydeD	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_2118653_4	313624.NSP_27160	5.295e-27	125.0	COG0457@1|root,COG0457@2|Bacteria,1G4DX@1117|Cyanobacteria,1HTVR@1161|Nostocales	1117|Cyanobacteria	K	Soluble NSF attachment protein, SNAP	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_8
LZS2_k127_2118653_3	349521.HCH_06118	3.234e-47	180.0	2EC04@1|root,335ZE@2|Bacteria,1NA1N@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1266
LZS2_k127_2118653_0	237368.SCABRO_00906	8.16e-106	365.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_2118653_2	1379698.RBG1_1C00001G0711	5.231e-91	317.0	COG0612@1|root,COG0612@2|Bacteria,2NQHV@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	ymxG	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_2118653_1	290397.Adeh_1659	9.399e-102	348.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
LZS2_k127_2118653_5	1286631.X805_09580	1.497e-12	80.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VHCV@28216|Betaproteobacteria,1KJIQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_213689_0	1379698.RBG1_1C00001G0598	1.033e-102	342.0	COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_213689_1	880072.Desac_1034	8.478e-99	340.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MQB7@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_213689_4	880073.Calab_1553	5.899e-40	157.0	COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
LZS2_k127_213689_5	945713.IALB_2581	2.514e-23	111.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_213689_6	1192034.CAP_7313	2.179e-06	62.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
LZS2_k127_213689_2	459349.CLOAM0575	5.631e-49	202.0	COG4412@1|root,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,FlgD_ig,Peptidase_M6
LZS2_k127_213689_7	1499967.BAYZ01000009_gene5344	0.0001992	53.0	COG1470@1|root,COG2885@1|root,COG1470@2|Bacteria,COG2885@2|Bacteria,2NPWP@2323|unclassified Bacteria	2|Bacteria	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF4384,DUF4625,OmpA,PEGA
LZS2_k127_213689_3	1379698.RBG1_1C00001G1236	2.666e-46	178.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
LZS2_k127_2160912_0	926561.KB900623_gene719	3.448e-137	454.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WA9E@53433|Halanaerobiales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
LZS2_k127_2160912_1	521098.Aaci_1329	3.369e-20	91.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4I3V5@91061|Bacilli,278KK@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
LZS2_k127_2160912_2	1321781.HMPREF1985_00031	0.0006148	46.0	COG1032@1|root,COG1032@2|Bacteria,1TQJT@1239|Firmicutes,4H23J@909932|Negativicutes	909932|Negativicutes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_2191086_2	649747.HMPREF0083_00974	2.477e-35	142.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HI9N@91061|Bacilli,26XD3@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_2191086_6	1121403.AUCV01000001_gene664	3.615e-12	70.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,42V1I@68525|delta/epsilon subdivisions,2WRH0@28221|Deltaproteobacteria,2MKP1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
LZS2_k127_2191086_5	1410631.JHWZ01000010_gene2084	2.249e-12	72.0	COG2172@1|root,COG2172@2|Bacteria,1VAPM@1239|Firmicutes,24J9J@186801|Clostridia,27MMM@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
LZS2_k127_2191086_7	459349.CLOAM1563	3.296e-06	50.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.17.22	ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBM_6,Cellulase,DUF4859,F5_F8_type_C,FlgD_ig
LZS2_k127_2191086_1	1379698.RBG1_1C00001G1218	8.788e-54	212.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS2_k127_2191086_4	1042877.GQS_00080	5.754e-14	86.0	arCOG03264@1|root,arCOG03264@2157|Archaea,2Y50J@28890|Euryarchaeota,244SG@183968|Thermococci	183968|Thermococci	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
LZS2_k127_2191086_3	118173.KB235914_gene842	1.429e-29	137.0	COG1262@1|root,COG1672@1|root,COG4249@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria,COG4249@2|Bacteria,1G0ZT@1117|Cyanobacteria,1H92Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14,TIR_2
LZS2_k127_2191086_8	1151117.AJLF01000001_gene1492	0.0003154	51.0	arCOG02559@1|root,arCOG03264@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	183968|Thermococci	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
LZS2_k127_2191086_0	1121920.AUAU01000018_gene1801	1.263e-81	279.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria	57723|Acidobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_2194959_0	745411.B3C1_12819	5.39e-185	606.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1J5F8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	AcrB/AcrD/AcrF family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_2194959_1	411902.CLOBOL_03671	7.568e-11	68.0	COG0845@1|root,COG0845@2|Bacteria,1V2JZ@1239|Firmicutes,24A5A@186801|Clostridia,22437@1506553|Lachnoclostridium	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS2_k127_2195678_4	536227.CcarbDRAFT_4613	9.034e-45	169.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,36EE6@31979|Clostridiaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
LZS2_k127_2195678_3	1121430.JMLG01000003_gene619	5.564e-61	226.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,260TT@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
LZS2_k127_2195678_0	1232410.KI421421_gene3865	4.877e-157	507.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,43T1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	UDP-N-acetylmuramate-L-alanine ligase activity	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_2195678_2	555079.Toce_0851	2.998e-62	226.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,42ETQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
LZS2_k127_2195678_6	240015.ACP_1082	4.674e-10	70.0	COG1589@1|root,COG1589@2|Bacteria,3Y3BQ@57723|Acidobacteria,2JIZS@204432|Acidobacteriia	204432|Acidobacteriia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
LZS2_k127_2195678_1	1499967.BAYZ01000069_gene1913	4.592e-118	392.0	COG0849@1|root,COG0849@2|Bacteria,2NNU2@2323|unclassified Bacteria	2|Bacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
LZS2_k127_2195678_5	272558.10175178	5.858e-40	151.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli,1ZC2F@1386|Bacillus	91061|Bacilli	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS2_k127_2196041_3	118005.AWNK01000011_gene148	4.329e-143	461.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS2_k127_2196041_0	118005.AWNK01000011_gene146	3.34e-219	710.0	COG4590@1|root,COG4590@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS2_k127_2196041_1	118005.AWNK01000011_gene145	1.913e-206	659.0	COG0581@1|root,COG0581@2|Bacteria	2|Bacteria	P	inorganic phosphate transmembrane transporter activity	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS2_k127_2196041_6	314230.DSM3645_15600	7.782e-129	417.0	COG1117@1|root,COG1117@2|Bacteria,2IWRV@203682|Planctomycetes	203682|Planctomycetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
LZS2_k127_2196041_10	69014.TK1339	7.312e-16	79.0	COG1476@1|root,arCOG01864@2157|Archaea,2XZS8@28890|Euryarchaeota,244GH@183968|Thermococci	183968|Thermococci	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
LZS2_k127_2196041_8	479434.Sthe_1768	3.634e-74	260.0	COG1131@1|root,COG1131@2|Bacteria,2G5QI@200795|Chloroflexi,27XXC@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_2196041_11	1210884.HG799465_gene12130	2.202e-07	62.0	COG1277@1|root,COG1277@2|Bacteria,2J0S8@203682|Planctomycetes	203682|Planctomycetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
LZS2_k127_2196041_4	156889.Mmc1_1606	1.298e-141	454.0	COG1830@1|root,COG1830@2|Bacteria,1MWJW@1224|Proteobacteria,2U27K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes	-	-	2.3.1.245,4.1.2.13	ko:K08321,ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02024,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02024	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
LZS2_k127_2196041_2	156889.Mmc1_1605	8.549e-206	662.0	COG3347@1|root,COG4221@1|root,COG3347@2|Bacteria,COG4221@2|Bacteria,1QVWU@1224|Proteobacteria,2TWVU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
LZS2_k127_2196041_7	335543.Sfum_4048	2.842e-86	300.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,42NP7@68525|delta/epsilon subdivisions,2WKJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM OsmC family protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,OsmC
LZS2_k127_2196041_9	156889.Mmc1_2110	1.317e-53	204.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria	1224|Proteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
LZS2_k127_2196041_5	1304880.JAGB01000002_gene1555	2.112e-131	434.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
LZS2_k127_2196041_12	604354.TSIB_1032	0.0009052	47.0	arCOG08223@1|root,arCOG08223@2157|Archaea,2Y0BP@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2250789_3	697281.Mahau_0500	6.161e-61	221.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,42EQ0@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
LZS2_k127_2250789_4	706587.Desti_0141	2.445e-22	103.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,42RIS@68525|delta/epsilon subdivisions,2WMWC@28221|Deltaproteobacteria,2MQMS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
LZS2_k127_2250789_1	639282.DEFDS_0916	2.701e-100	344.0	COG1951@1|root,COG1951@2|Bacteria,2GER7@200930|Deferribacteres	200930|Deferribacteres	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
LZS2_k127_2250789_2	926569.ANT_30970	1.878e-69	241.0	COG1838@1|root,COG1838@2|Bacteria,2G74D@200795|Chloroflexi	200795|Chloroflexi	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
LZS2_k127_2250789_0	760568.Desku_3120	1.294e-205	648.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,260TY@186807|Peptococcaceae	186801|Clostridia	C	Aconitase family (aconitate hydratase)	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
LZS2_k127_2285177_7	118166.JH976538_gene5202	2.454e-10	74.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales	1117|Cyanobacteria	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,TPR_12,TPR_7,TPR_8
LZS2_k127_2285177_1	1047013.AQSP01000123_gene1542	2.274e-151	492.0	COG2204@1|root,COG2204@2|Bacteria,2NP3X@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_2285177_2	1379698.RBG1_1C00001G1097	1.234e-82	287.0	COG0820@1|root,COG0820@2|Bacteria,2NP4V@2323|unclassified Bacteria	2|Bacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
LZS2_k127_2285177_8	880073.Calab_0913	2.221e-09	70.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
LZS2_k127_2285177_4	1123489.AUAN01000008_gene142	3.168e-25	123.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,4H27F@909932|Negativicutes	909932|Negativicutes	M	Outer membrane protein, OMP85 family	yaeT	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS2_k127_2285177_5	56780.SYN_00516	3.619e-13	81.0	COG1664@1|root,COG1664@2|Bacteria,1MUS9@1224|Proteobacteria,43BNZ@68525|delta/epsilon subdivisions,2X70B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2285177_9	196162.Noca_4536	2.615e-05	54.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4DQMV@85009|Propionibacteriales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
LZS2_k127_2285177_6	379066.GAU_2304	2.808e-12	78.0	COG3595@1|root,COG3595@2|Bacteria,1ZTJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
LZS2_k127_2285177_3	880073.Calab_1183	5.556e-47	177.0	COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_2285177_0	945713.IALB_2801	1.646e-187	594.0	COG0148@1|root,COG0148@2|Bacteria	2|Bacteria	G	phosphopyruvate hydratase activity	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
LZS2_k127_2285177_10	330214.NIDE2912	3.576e-05	52.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	ftsB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
LZS2_k127_2303486_15	517418.Ctha_2294	2.928e-30	133.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS2_k127_2303486_19	880073.Calab_0646	1.76e-17	97.0	COG1572@1|root,COG1595@1|root,COG1572@2|Bacteria,COG1595@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	CARDB,Sigma70_r4_2
LZS2_k127_2303486_17	1407650.BAUB01000006_gene1432	1.038e-22	114.0	COG2133@1|root,COG2133@2|Bacteria,1GP2C@1117|Cyanobacteria,1H24N@1129|Synechococcus	1117|Cyanobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2303486_21	1345697.M493_18085	3.037e-13	83.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1WG24@129337|Geobacillus	91061|Bacilli	G	Glycosyl hydrolases family 32	sacA	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	iYO844.BSU38040	Glyco_hydro_32C,Glyco_hydro_32N
LZS2_k127_2303486_9	460265.Mnod_1497	1.434e-63	231.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,2TTFW@28211|Alphaproteobacteria,1JQV8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBS,Peptidase_M50
LZS2_k127_2303486_23	243231.GSU1057	3.552e-11	71.0	COG0457@1|root,COG0457@2|Bacteria,1P22J@1224|Proteobacteria,4310H@68525|delta/epsilon subdivisions,2WWBW@28221|Deltaproteobacteria,43VHQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2303486_25	118168.MC7420_6580	4.059e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_2,TPR_8
LZS2_k127_2303486_1	671143.DAMO_2552	4.448e-150	488.0	COG2256@1|root,COG2256@2|Bacteria,2NNTG@2323|unclassified Bacteria	2|Bacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
LZS2_k127_2303486_20	1435356.Y013_07365	7.714e-15	89.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4FVU3@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS2_k127_2303486_12	290397.Adeh_0097	1.108e-53	217.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YU2G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS2_k127_2303486_13	1131269.AQVV01000016_gene1838	2.571e-50	187.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	pgp	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS2_k127_2303486_11	667014.Thein_2204	1.794e-60	222.0	28I4Y@1|root,2Z88D@2|Bacteria,2GI90@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2303486_2	1379698.RBG1_1C00001G1779	8.233e-142	456.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_2303486_3	880073.Calab_2467	2.873e-93	320.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
LZS2_k127_2303486_18	1122179.KB890425_gene3368	1.688e-19	100.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1ISTW@117747|Sphingobacteriia	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2303486_4	880073.Calab_2474	6.419e-90	307.0	COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria	2|Bacteria	NU	von Willebrand factor (vWF) type A domain	batA	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
LZS2_k127_2303486_5	1379698.RBG1_1C00001G1774	2.21e-87	316.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
LZS2_k127_2303486_6	1379698.RBG1_1C00001G1773	1.258e-84	303.0	COG0457@1|root,COG0457@2|Bacteria,2NP5J@2323|unclassified Bacteria	2|Bacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
LZS2_k127_2303486_16	445970.ALIPUT_00891	4.88e-26	119.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22V8H@171550|Rikenellaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
LZS2_k127_2303486_22	504728.K649_03755	4.026e-12	74.0	COG1246@1|root,COG1246@2|Bacteria,1WN4A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7
LZS2_k127_2303486_26	344747.PM8797T_30796	2.524e-05	56.0	COG1716@1|root,COG3852@1|root,COG1716@2|Bacteria,COG3852@2|Bacteria,2IWYR@203682|Planctomycetes	203682|Planctomycetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HATPase_c,Yop-YscD_cpl
LZS2_k127_2303486_10	485913.Krac_7826	9.026e-61	218.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS2_k127_2303486_8	1210884.HG799470_gene14435	7.497e-65	241.0	COG3437@1|root,COG3437@2|Bacteria,2J518@203682|Planctomycetes	203682|Planctomycetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5
LZS2_k127_2303486_0	639282.DEFDS_1169	1.937e-293	917.0	COG0209@1|root,COG0209@2|Bacteria,2GERH@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
LZS2_k127_2303486_7	635013.TherJR_1590	7.096e-78	270.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,26081@186807|Peptococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
LZS2_k127_2303486_14	316067.Geob_2739	1.65e-37	149.0	29IJ4@1|root,313M6@2|Bacteria,1R385@1224|Proteobacteria,43DJI@68525|delta/epsilon subdivisions,2X8QT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
LZS2_k127_2312724_4	416348.Hlac_3592	3.891e-49	194.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS2_k127_2312724_6	945713.IALB_1092	4.649e-17	83.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
LZS2_k127_2312724_0	945713.IALB_1093	9.409e-294	906.0	28I8B@1|root,2Z8B5@2|Bacteria	2|Bacteria	C	PFAM Cytochrome c, bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Cytochrome_cB
LZS2_k127_2312724_2	945713.IALB_1094	2.985e-104	342.0	COG4117@1|root,COG4117@2|Bacteria	2|Bacteria	C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
LZS2_k127_2312724_3	945713.IALB_1095	5.145e-84	282.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
LZS2_k127_2312724_1	945713.IALB_1096	1.561e-175	557.0	COG0607@1|root,COG2391@1|root,COG0607@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	M1-359	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Cu_amine_oxidN1,DUF4344,Sulf_transp
LZS2_k127_2312724_5	515635.Dtur_0534	3.489e-20	94.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
LZS2_k127_2312724_7	1121405.dsmv_3770	6.062e-17	83.0	COG1342@1|root,COG1342@2|Bacteria,1N80T@1224|Proteobacteria,42TAM@68525|delta/epsilon subdivisions,2WP9H@28221|Deltaproteobacteria,2MK4A@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function  DUF134	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
LZS2_k127_2433328_2	1379698.RBG1_1C00001G0593	1.373e-06	50.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin_3,DUF11,FlgD_ig
LZS2_k127_2433328_0	1121129.KB903359_gene2508	1.353e-166	532.0	COG0520@1|root,COG0520@2|Bacteria,4NG72@976|Bacteroidetes,2FQA1@200643|Bacteroidia,230GJ@171551|Porphyromonadaceae	976|Bacteroidetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS2_k127_2433328_3	357808.RoseRS_4627	9.187e-05	53.0	COG2203@1|root,COG3605@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3920@2|Bacteria,2G67M@200795|Chloroflexi,374WN@32061|Chloroflexia	32061|Chloroflexia	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,HisKA_2
LZS2_k127_2433328_1	595460.RRSWK_05435	1.142e-11	78.0	2EYTK@1|root,33S0U@2|Bacteria,2IYA9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1
LZS2_k127_2436558_3	518766.Rmar_0508	6.297e-101	349.0	COG2203@1|root,COG2204@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	Sigma54_activat
LZS2_k127_2436558_9	269797.Mbar_A3539	1.202e-23	102.0	COG3478@1|root,arCOG05073@2157|Archaea	2157|Archaea	S	nucleic-acid-binding protein containing a Zn-ribbon domain	-	-	-	ko:K07069	-	-	-	-	ko00000	-	-	-	zinc_ribbon_13
LZS2_k127_2436558_4	1220534.B655_0176	4.593e-81	297.0	COG1950@1|root,arCOG09731@2157|Archaea,2Y2F9@28890|Euryarchaeota,23PAN@183925|Methanobacteria	183925|Methanobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
LZS2_k127_2436558_6	926550.CLDAP_40500	9.479e-56	204.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	2|Bacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS2_k127_2436558_5	880073.Calab_1819	6.147e-74	265.0	COG3170@1|root,COG3170@2|Bacteria,2NPXD@2323|unclassified Bacteria	2|Bacteria	NU	Tfp pilus assembly protein FimV	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	DUF4157,Pkinase
LZS2_k127_2436558_1	880073.Calab_1818	1.756e-117	388.0	COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
LZS2_k127_2436558_7	880073.Calab_1817	1.179e-47	183.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
LZS2_k127_2436558_8	880073.Calab_1817	1.317e-45	175.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
LZS2_k127_2436558_2	986075.CathTA2_3050	1.612e-102	350.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,4H9KW@91061|Bacilli	91061|Bacilli	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
LZS2_k127_2436558_0	639282.DEFDS_0463	4.238e-235	745.0	COG3808@1|root,COG3808@2|Bacteria,2GFAJ@200930|Deferribacteres	200930|Deferribacteres	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
LZS2_k127_2508325_7	1121468.AUBR01000022_gene2780	8.844e-58	204.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,42EPM@68295|Thermoanaerobacterales	186801|Clostridia	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
LZS2_k127_2508325_5	1304874.JAFY01000007_gene2036	2.755e-79	279.0	COG0265@1|root,COG0265@2|Bacteria,3TACF@508458|Synergistetes	508458|Synergistetes	M	TIGRFAM periplasmic serine protease, Do DeqQ family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_2508325_3	1121423.JONT01000010_gene1745	3.682e-162	521.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,260RX@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
LZS2_k127_2508325_1	1122164.JHWF01000001_gene2031	2.722e-175	577.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS2_k127_2508325_9	1094715.CM001373_gene3315	1.171e-51	192.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,1SVID@1236|Gammaproteobacteria,1JD85@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
LZS2_k127_2508325_2	1379698.RBG1_1C00001G1211	1.469e-173	556.0	COG0034@1|root,COG0034@2|Bacteria,2NNSY@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
LZS2_k127_2508325_12	1121468.AUBR01000001_gene513	1.749e-21	104.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,42G8C@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
LZS2_k127_2508325_4	1499967.BAYZ01000029_gene1223	3.889e-138	456.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
LZS2_k127_2508325_11	926556.Echvi_1775	3.896e-27	113.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,47R7R@768503|Cytophagia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
LZS2_k127_2508325_10	195103.CPF_2383	1.502e-33	130.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,36JKM@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
LZS2_k127_2508325_8	373903.Hore_18930	2e-57	210.0	COG1212@1|root,COG1212@2|Bacteria,1TQU3@1239|Firmicutes,24H2B@186801|Clostridia,3WAKF@53433|Halanaerobiales	186801|Clostridia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
LZS2_k127_2508325_0	697284.ERIC2_c39010	2.719e-222	701.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli,26RTB@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
LZS2_k127_2508325_6	330214.NIDE2556	4.751e-78	270.0	COG2877@1|root,COG2877@2|Bacteria,3J0AK@40117|Nitrospirae	40117|Nitrospirae	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
LZS2_k127_2565926_16	686578.AFFX01000002_gene582	1.223e-25	119.0	COG0421@1|root,COG0421@2|Bacteria,1QVJA@1224|Proteobacteria,1RYYT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
LZS2_k127_2565926_5	1125863.JAFN01000001_gene1446	8.34e-134	445.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_2565926_14	1379698.RBG1_1C00001G0578	2.889e-55	207.0	COG3852@1|root,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9
LZS2_k127_2565926_7	1121447.JONL01000007_gene1310	1.038e-81	289.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2M8K7@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS2_k127_2565926_4	1307759.JOMJ01000003_gene2352	2.853e-134	451.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2M9X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
LZS2_k127_2565926_0	382464.ABSI01000011_gene2351	0.0	1602.0	COG0841@1|root,COG0841@2|Bacteria,46Z6Y@74201|Verrucomicrobia,2ITZB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS2_k127_2565926_9	1191523.MROS_0039	3.05e-67	239.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	sco	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS2_k127_2565926_2	269799.Gmet_0249	1.112e-243	762.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions,2WJUK@28221|Deltaproteobacteria,43S0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1
LZS2_k127_2565926_11	945713.IALB_1395	7.715e-64	241.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
LZS2_k127_2565926_18	1121918.ARWE01000001_gene594	4.608e-18	87.0	2EAMQ@1|root,334Q9@2|Bacteria,1NA2T@1224|Proteobacteria,42VC9@68525|delta/epsilon subdivisions,2WRD9@28221|Deltaproteobacteria,43SRT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	coxD	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
LZS2_k127_2565926_6	1168034.FH5T_09805	2.092e-88	302.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,2FX9N@200643|Bacteroidia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
LZS2_k127_2565926_12	945713.IALB_1398	3.459e-59	216.0	COG0109@1|root,COG0109@2|Bacteria	2|Bacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
LZS2_k127_2565926_15	1232410.KI421425_gene1567	5.496e-40	165.0	COG4654@1|root,COG4654@2|Bacteria,1NJV5@1224|Proteobacteria,42XIC@68525|delta/epsilon subdivisions,2WTEX@28221|Deltaproteobacteria,43UUU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS2_k127_2565926_13	1232410.KI421425_gene1566	7.804e-56	200.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2X7M4@28221|Deltaproteobacteria,43VY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2565926_1	1232410.KI421425_gene1565	2.562e-288	912.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,43TY6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS2_k127_2565926_3	1232410.KI421425_gene1564	6.218e-203	639.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
LZS2_k127_2565926_17	1232410.KI421425_gene1563	1.465e-22	110.0	COG2010@1|root,COG2010@2|Bacteria,1PWTD@1224|Proteobacteria,437B9@68525|delta/epsilon subdivisions,2X9ZG@28221|Deltaproteobacteria,43V90@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS2_k127_2565926_8	1232410.KI421425_gene1562	3.756e-72	255.0	COG5557@1|root,COG5557@2|Bacteria,1QURB@1224|Proteobacteria,43BT1@68525|delta/epsilon subdivisions,2X73S@28221|Deltaproteobacteria,43SR9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pfam Polysulphide reductase, NrfD	actF	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2565926_10	1499967.BAYZ01000164_gene6670	6.087e-66	233.0	COG3907@1|root,COG3907@2|Bacteria	2|Bacteria	S	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
LZS2_k127_2565926_19	670487.Ocepr_0941	1.023e-09	67.0	COG3634@1|root,COG3634@2|Bacteria,1WJHV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	TIGRFAM Glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
LZS2_k127_258038_1	1209989.TepiRe1_0048	2.53e-85	286.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,42G2C@68295|Thermoanaerobacterales	186801|Clostridia	C	Aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh,Pro_dh
LZS2_k127_258038_2	1237149.C900_05249	5.362e-57	213.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
LZS2_k127_258038_0	1382306.JNIM01000001_gene665	0.0	1040.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS2_k127_2584850_0	339860.Msp_0117	2.023e-143	462.0	COG3425@1|root,arCOG01767@2157|Archaea,2XTWE@28890|Euryarchaeota,23NSI@183925|Methanobacteria	183925|Methanobacteria	I	Belongs to the UPF0219 family	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,HMG_CoA_synt_N
LZS2_k127_2584850_1	420247.Msm_1562	7.929e-143	464.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,23NRQ@183925|Methanobacteria	183925|Methanobacteria	I	Thiolase, N-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_2584850_2	694431.DESACE_06835	3.211e-31	126.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	phlB	-	-	ko:K07068,ko:K07549	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05587	RC00004,RC01428,RC02904	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF35_N,OB_aCoA_assoc
LZS2_k127_2602327_2	1536774.H70357_05585	5.978e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,1VDV4@1239|Firmicutes,4IPUE@91061|Bacilli,26X10@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_2602327_3	1125863.JAFN01000001_gene2799	3.131e-33	133.0	COG0824@1|root,COG0824@2|Bacteria,1REIH@1224|Proteobacteria,42UZ3@68525|delta/epsilon subdivisions,2WQAZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
LZS2_k127_2602327_4	1519464.HY22_13125	0.0004827	44.0	COG0737@1|root,COG1520@1|root,COG0737@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
LZS2_k127_2602327_0	383372.Rcas_0893	5.59e-164	542.0	COG0607@1|root,COG0659@1|root,COG0607@2|Bacteria,COG0659@2|Bacteria,2G83D@200795|Chloroflexi,3764C@32061|Chloroflexia	32061|Chloroflexia	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Rhodanese,STAS,Sulfate_transp
LZS2_k127_2602327_1	880073.Calab_1754	5.354e-89	320.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
LZS2_k127_2682840_0	1123267.JONN01000001_gene1238	1.773e-209	686.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MRJP
LZS2_k127_2682840_2	1123267.JONN01000001_gene1239	3.823e-27	123.0	2C1YS@1|root,2ZD2Y@2|Bacteria	2|Bacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
LZS2_k127_2682840_1	1379698.RBG1_1C00001G0520	6.961e-46	175.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	CHASE2,GAF,GAF_2,HATPase_c_2,SpoIIE
LZS2_k127_2690325_4	1121440.AUMA01000009_gene689	8.203e-05	51.0	COG0457@1|root,COG0457@2|Bacteria,1R51F@1224|Proteobacteria,42NP1@68525|delta/epsilon subdivisions,2WMJ3@28221|Deltaproteobacteria,2M89Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_2690325_2	324925.Ppha_0500	1.048e-21	104.0	COG0170@1|root,COG0170@2|Bacteria,1FDXW@1090|Chlorobi	1090|Chlorobi	I	PFAM phosphatidate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2690325_3	591158.SSMG_03430	1.231e-08	67.0	COG3391@1|root,COG3391@2|Bacteria,2GWAV@201174|Actinobacteria	201174|Actinobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS2_k127_2690325_1	1144275.COCOR_03208	2.29e-29	136.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2YV6T@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
LZS2_k127_2690325_0	880073.Calab_0772	1.992e-148	479.0	COG0519@1|root,COG0519@2|Bacteria,2NNRS@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.3.1.128,6.3.5.2	ko:K01951,ko:K03790	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002,ko03009	-	-	iLJ478.TM1820	GATase,GMP_synt_C,NAD_synthase
LZS2_k127_276731_19	756499.Desde_0423	7.665e-39	148.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,2620M@186807|Peptococcaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
LZS2_k127_276731_8	351607.Acel_0306	9.992e-68	235.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4ERGJ@85013|Frankiales	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
LZS2_k127_276731_11	1408422.JHYF01000014_gene303	6.682e-60	213.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,36DFP@31979|Clostridiaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
LZS2_k127_276731_26	1125863.JAFN01000001_gene3297	3.252e-24	105.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
LZS2_k127_276731_1	398767.Glov_1349	2.021e-123	400.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,43T1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
LZS2_k127_276731_21	643648.Slip_2233	2.085e-36	139.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,42K2B@68298|Syntrophomonadaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
LZS2_k127_276731_28	1120917.AQXM01000026_gene306	3.416e-22	99.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,1W998@1268|Micrococcaceae	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
LZS2_k127_276731_3	269796.Rru_A2682	5.375e-87	295.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,2JQ8H@204441|Rhodospirillales	204441|Rhodospirillales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
LZS2_k127_276731_9	656519.Halsa_1914	5.656e-67	229.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WAKN@53433|Halanaerobiales	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
LZS2_k127_276731_30	1033743.CAES01000111_gene1468	1.1e-11	67.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli,26ZBS@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
LZS2_k127_276731_25	588581.Cpap_1359	1.873e-29	119.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WJV0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
LZS2_k127_276731_13	1408422.JHYF01000014_gene294	1.056e-54	193.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,36IUH@31979|Clostridiaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
LZS2_k127_276731_23	243164.DET0485	9.551e-32	126.0	COG0198@1|root,COG0198@2|Bacteria,2G750@200795|Chloroflexi,34DCX@301297|Dehalococcoidia	301297|Dehalococcoidia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
LZS2_k127_276731_5	635013.TherJR_0308	1.849e-78	265.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,2603I@186807|Peptococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
LZS2_k127_276731_27	324602.Caur_2382	1.044e-23	102.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi,375ZA@32061|Chloroflexia	32061|Chloroflexia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
LZS2_k127_276731_15	1449126.JQKL01000050_gene2688	3.933e-48	179.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,2696T@186813|unclassified Clostridiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
LZS2_k127_276731_10	1211035.CD30_03535	6.818e-62	218.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,3IXNM@400634|Lysinibacillus	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
LZS2_k127_276731_20	525904.Tter_0731	7.648e-37	142.0	COG0256@1|root,COG0256@2|Bacteria,2NPVI@2323|unclassified Bacteria	2|Bacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
LZS2_k127_276731_12	880073.Calab_2143	3.632e-59	211.0	COG0098@1|root,COG0098@2|Bacteria,2NPGN@2323|unclassified Bacteria	2|Bacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
LZS2_k127_276731_32	42256.RradSPS_1925	3.904e-11	65.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4CQVX@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
LZS2_k127_276731_16	335543.Sfum_1574	1.76e-47	174.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2WQQ4@28221|Deltaproteobacteria,2MQJN@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
LZS2_k127_276731_0	1499967.BAYZ01000114_gene2902	3.978e-178	567.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
LZS2_k127_276731_7	693661.Arcve_1092	6.316e-69	241.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
LZS2_k127_276731_4	748449.Halha_0210	1.596e-84	287.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WA6N@53433|Halanaerobiales	186801|Clostridia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
LZS2_k127_276731_22	653733.Selin_0354	2.22e-33	130.0	COG0361@1|root,COG0361@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
LZS2_k127_276731_31	694431.DESACE_01960	1.106e-11	66.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2M7HN@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
LZS2_k127_276731_17	269796.Rru_A2666	3.418e-43	160.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,2JS7G@204441|Rhodospirillales	204441|Rhodospirillales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
LZS2_k127_276731_14	1379698.RBG1_1C00001G1570	2.118e-49	180.0	COG0100@1|root,COG0100@2|Bacteria,2NPCN@2323|unclassified Bacteria	2|Bacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
LZS2_k127_276731_6	335543.Sfum_1581	7.756e-77	262.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2MRHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
LZS2_k127_276731_2	1379698.RBG1_1C00001G1568	7.261e-103	344.0	COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
LZS2_k127_276731_24	665571.STHERM_c05220	4.819e-31	130.0	COG0203@1|root,COG0203@2|Bacteria,2J841@203691|Spirochaetes	203691|Spirochaetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
LZS2_k127_276731_18	459349.CLOAM0244	2.516e-40	165.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF4985,GHL10
LZS2_k127_276731_29	1395587.P364_0127175	1.751e-17	87.0	COG0640@1|root,COG0640@2|Bacteria,1VF14@1239|Firmicutes,4HP8Z@91061|Bacilli,26YZT@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
LZS2_k127_276731_33	309801.trd_A0832	4.402e-09	59.0	COG2331@1|root,COG2331@2|Bacteria,2G7IB@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
LZS2_k127_2780946_3	379066.GAU_1933	2.02e-16	93.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
LZS2_k127_2780946_4	1144275.COCOR_06266	6.486e-11	75.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
LZS2_k127_2780946_1	1121468.AUBR01000045_gene1802	2.993e-114	383.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,42EXG@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS2_k127_2780946_0	1382358.JHVN01000007_gene355	1.76e-258	807.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,21V62@150247|Anoxybacillus	91061|Bacilli	E	Urocanase C-terminal domain	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
LZS2_k127_2780946_2	1536773.R70331_20210	1.2e-52	203.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,26T6Z@186822|Paenibacillaceae	91061|Bacilli	L	helicase involved in DNA repair and perhaps also replication	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
LZS2_k127_2811366_4	243274.THEMA_00435	0.0001721	53.0	COG1470@1|root,COG1470@2|Bacteria,2GDQF@200918|Thermotogae	200918|Thermotogae	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
LZS2_k127_2811366_0	1379698.RBG1_1C00001G0497	8.318e-30	128.0	COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
LZS2_k127_2811366_1	1379698.RBG1_1C00001G0498	1.933e-24	107.0	COG0848@1|root,COG0848@2|Bacteria,2NPWJ@2323|unclassified Bacteria	2|Bacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS2_k127_2811366_3	1125863.JAFN01000001_gene1510	7.13e-10	68.0	COG0810@1|root,COG0810@2|Bacteria,1NI45@1224|Proteobacteria,42VVY@68525|delta/epsilon subdivisions,2WRZC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
LZS2_k127_2811366_2	671143.DAMO_0497	1.115e-21	103.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS2_k127_2895120_2	1131269.AQVV01000017_gene1990	2.959e-81	274.0	COG1220@1|root,COG1220@2|Bacteria	2|Bacteria	O	peptidase activity, acting on L-amino acid peptides	hslU	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
LZS2_k127_2895120_1	880073.Calab_0179	1.271e-97	328.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS2_k127_2895120_7	1089550.ATTH01000001_gene963	2.936e-18	97.0	COG2372@1|root,COG2372@2|Bacteria,4PM5M@976|Bacteroidetes,1FIJV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CarboxypepD_reg
LZS2_k127_2895120_4	497964.CfE428DRAFT_0870	8.864e-71	249.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
LZS2_k127_2895120_3	1125863.JAFN01000001_gene2756	4.135e-78	274.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS2_k127_2895120_5	247490.KSU1_C1120	2.389e-46	177.0	COG0289@1|root,COG0289@2|Bacteria,2IX9G@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
LZS2_k127_2895120_0	1379698.RBG1_1C00001G1445	1.772e-165	554.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
LZS2_k127_2895120_6	203122.Sde_0909	5.591e-33	129.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,4652J@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iUTI89_1310.UTI89_C0210	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
LZS2_k127_2895391_7	525904.Tter_2807	2.459e-48	187.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_2895391_4	485913.Krac_8056	1.057e-70	255.0	COG0726@1|root,COG0726@2|Bacteria,2G8HZ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS2_k127_2895391_5	525904.Tter_2798	7.39e-62	227.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	epsD	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754,ko:K19422	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_2895391_2	525904.Tter_2796	4.523e-80	289.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	-	2.1.1.45,2.7.4.9	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02094,R02098,R02101	RC00002,RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS2_k127_2895391_6	525904.Tter_2795	1.841e-60	221.0	COG0438@1|root,COG0438@2|Bacteria,2NPSJ@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
LZS2_k127_2895391_1	1211815.CBYP010000034_gene2129	2.192e-80	282.0	COG0438@1|root,COG0438@2|Bacteria,2GSQI@201174|Actinobacteria,4ES49@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_2895391_0	237368.SCABRO_03724	3.692e-174	565.0	COG1389@1|root,COG1389@2|Bacteria,2J2A8@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
LZS2_k127_2895391_3	237368.SCABRO_03725	5.32e-74	252.0	COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
LZS2_k127_2915368_4	1137799.GZ78_09640	0.0002559	44.0	2DD8W@1|root,2ZH3F@2|Bacteria,1PBGJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2915368_3	485915.Dret_0882	5.571e-05	47.0	2DD8W@1|root,2ZH3F@2|Bacteria,1PBGJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2915368_1	1121939.L861_13660	1.638e-38	149.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,1T1IK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
LZS2_k127_2915368_2	1322246.BN4_11065	5.351e-27	113.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WRRT@28221|Deltaproteobacteria,2MCID@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS2_k127_2915368_0	644282.Deba_0036	2.79e-138	448.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WJCC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
LZS2_k127_2922791_8	671143.DAMO_2726	5.803e-30	123.0	COG3654@1|root,COG3654@2|Bacteria,2NRTS@2323|unclassified Bacteria	2|Bacteria	S	Fic/DOC family	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
LZS2_k127_2922791_1	1237149.C900_03836	7.157e-155	503.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	putP_2	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
LZS2_k127_2922791_10	264732.Moth_0665	5.631e-16	91.0	COG1807@1|root,COG1807@2|Bacteria,1V1HJ@1239|Firmicutes,249BG@186801|Clostridia,42HAV@68295|Thermoanaerobacterales	186801|Clostridia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS2_k127_2922791_3	1123277.KB893175_gene1396	1.116e-99	338.0	COG1373@1|root,COG1373@2|Bacteria,4NE39@976|Bacteroidetes,47MF2@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
LZS2_k127_2922791_2	661478.OP10G_3197	1.213e-104	361.0	28MB8@1|root,2ZAPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2922791_4	1047013.AQSP01000140_gene2451	1.572e-63	229.0	COG0066@1|root,COG0066@2|Bacteria,2NPKG@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
LZS2_k127_2922791_0	1047013.AQSP01000140_gene2450	1.805e-162	521.0	COG0065@1|root,COG0065@2|Bacteria,2NNYT@2323|unclassified Bacteria	2|Bacteria	E	Aconitase family (aconitate hydratase)	hacA	-	4.2.1.114,4.2.1.33,4.2.1.35,4.2.1.36	ko:K01703,ko:K01705,ko:K16792	ko00290,ko00300,ko00660,ko00680,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00680,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535,M00608	R03444,R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R09720,R10170,R10391,R10392,R10393,R10394,R10395,R10396	RC00497,RC00498,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
LZS2_k127_2922791_9	1267535.KB906767_gene200	5.03e-26	112.0	COG1959@1|root,COG1959@2|Bacteria,3Y4X0@57723|Acidobacteria,2JJEV@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS2_k127_2922791_7	1123503.KB908056_gene1699	4.067e-37	147.0	COG4319@1|root,COG4319@2|Bacteria,1MZRB@1224|Proteobacteria,2UK7M@28211|Alphaproteobacteria,2KHHC@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
LZS2_k127_2922791_6	1230341.MJ3_05223	8.654e-38	151.0	2DPEU@1|root,331SS@2|Bacteria,1VE8J@1239|Firmicutes,4HMSY@91061|Bacilli	91061|Bacilli	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
LZS2_k127_2922791_11	1089550.ATTH01000001_gene1005	6.994e-07	61.0	COG1404@1|root,COG3591@1|root,COG4932@1|root,COG1404@2|Bacteria,COG3591@2|Bacteria,COG4932@2|Bacteria,4NG2K@976|Bacteroidetes,1FJTD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EO	Trypsin-like serine protease	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin_2
LZS2_k127_2922791_5	471854.Dfer_3148	8.462e-44	168.0	COG2931@1|root,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
LZS2_k127_2933887_8	1123508.JH636442_gene4097	6.09e-15	88.0	28NUF@1|root,33DCF@2|Bacteria,2J1TB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_2933887_4	335543.Sfum_1153	4.342e-61	218.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42QJY@68525|delta/epsilon subdivisions,2WK0U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
LZS2_k127_2933887_3	1121440.AUMA01000012_gene1399	5.409e-81	289.0	COG2270@1|root,COG2270@2|Bacteria,1QXKZ@1224|Proteobacteria	1224|Proteobacteria	S	Pfam Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_2933887_2	1379698.RBG1_1C00001G1816	7.144e-88	316.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
LZS2_k127_2933887_6	1230342.CTM_19749	1.083e-44	182.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36ERF@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE3,PAS,PAS_3,PAS_8,PAS_9
LZS2_k127_2933887_7	237368.SCABRO_01312	8.636e-16	81.0	COG0355@1|root,COG0355@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	ATP-synt_DE,ATP-synt_DE_N
LZS2_k127_2933887_0	1379698.RBG1_1C00001G0153	3.18e-232	726.0	COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS2_k127_2933887_5	1131462.DCF50_p2879	6.043e-55	204.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,2601T@186807|Peptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
LZS2_k127_2933887_1	1379698.RBG1_1C00001G0150	4.55e-129	417.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS2_k127_2936748_5	1211813.CAPH01000023_gene1972	8.808e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,4NIRG@976|Bacteroidetes,2FRYA@200643|Bacteroidia,22UIK@171550|Rikenellaceae	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_2936748_0	1379698.RBG1_1C00001G1218	4.432e-132	451.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS2_k127_2936748_3	1429851.X548_04950	1.374e-37	145.0	COG1695@1|root,COG1695@2|Bacteria,1NJSY@1224|Proteobacteria,1SG6R@1236|Gammaproteobacteria,1X6UG@135614|Xanthomonadales	135614|Xanthomonadales	K	PadR family transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
LZS2_k127_2936748_2	1300345.LF41_2556	3.166e-68	242.0	COG4709@1|root,COG4709@2|Bacteria,1NX5K@1224|Proteobacteria,1SPS6@1236|Gammaproteobacteria,1X34I@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
LZS2_k127_2936748_1	402777.KB235904_gene3532	1.572e-78	268.0	COG1011@1|root,COG1011@2|Bacteria,1G4JI@1117|Cyanobacteria,1H8VT@1150|Oscillatoriales	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS2_k127_2936748_4	290397.Adeh_0859	1.56e-27	126.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS2_k127_2952886_1	1191523.MROS_2663	1.918e-267	833.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	nifJ	GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.nifJ,iLF82_1304.LF82_2789,iNRG857_1313.NRG857_06920	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS2_k127_2952886_2	880073.Calab_1546	1.536e-142	459.0	COG0167@1|root,COG0167@2|Bacteria,2NPB9@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS2_k127_2952886_6	1191523.MROS_1825	7.454e-20	105.0	COG4412@1|root,COG4447@1|root,COG4412@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4859,FlgD_ig,PSII_BNR
LZS2_k127_2952886_3	247490.KSU1_C0449	1.207e-101	355.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS2_k127_2952886_7	459349.CLOAM1790	2.702e-18	100.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
LZS2_k127_2952886_4	247490.KSU1_C0449	1.416e-98	346.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS2_k127_2952886_0	880073.Calab_0811	3.484e-273	856.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	PD40,Peptidase_S9
LZS2_k127_2952886_5	555088.DealDRAFT_1743	9.851e-51	203.0	COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,25CFE@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
LZS2_k127_2952886_8	487316.BBNM01000005_gene125	1.149e-06	50.0	2A2R8@1|root,30R45@2|Bacteria,1QBY9@1224|Proteobacteria,1T7JH@1236|Gammaproteobacteria,3NSE4@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3068435_0	1379698.RBG1_1C00001G1092	2.288e-142	480.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
LZS2_k127_3068435_2	945713.IALB_2586	6.486e-11	76.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Lipase_GDSL_2,Polysacc_deac_1,SLH
LZS2_k127_3068435_1	1121406.JAEX01000007_gene2455	6.402e-78	277.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2M9ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_3071224_7	706587.Desti_1118	1.904e-47	175.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,42SN5@68525|delta/epsilon subdivisions,2WP28@28221|Deltaproteobacteria,2MS2U@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	DsrC like protein	dsrC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
LZS2_k127_3071224_8	880073.Calab_0942	4.976e-36	145.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
LZS2_k127_3071224_6	1121423.JONT01000001_gene2038	2.284e-57	203.0	COG1146@1|root,COG1146@2|Bacteria,1V59C@1239|Firmicutes,24J64@186801|Clostridia,261U8@186807|Peptococcaceae	186801|Clostridia	C	reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_7,Fer4_9
LZS2_k127_3071224_0	760568.Desku_1074	2.743e-307	952.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,25ZZD@186807|Peptococcaceae	186801|Clostridia	C	reductase alpha subunit	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS2_k127_3071224_9	335543.Sfum_1055	1.347e-23	104.0	COG0500@1|root,COG2226@2|Bacteria,1NHMR@1224|Proteobacteria,42XMB@68525|delta/epsilon subdivisions,2WT6Q@28221|Deltaproteobacteria,2MSC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	Ogr/Delta-like zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	Ogr_Delta
LZS2_k127_3071224_5	289376.THEYE_A0135	6.079e-64	229.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
LZS2_k127_3071224_3	646529.Desaci_2315	8.936e-157	507.0	COG1148@1|root,COG1148@2|Bacteria,1TS8Y@1239|Firmicutes,24CXD@186801|Clostridia,2604G@186807|Peptococcaceae	186801|Clostridia	C	binding domain	-	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,Fer4,Fer4_10,Fer4_7,Fer4_9,NAD_binding_8,Pyr_redox_2
LZS2_k127_3071224_1	1121468.AUBR01000049_gene1632	2.172e-272	857.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,42FPJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
LZS2_k127_3071224_4	387631.Asulf_02108	2.511e-104	350.0	COG0247@1|root,COG2048@1|root,arCOG00964@2157|Archaea,arCOG05014@2157|Archaea,2XVUC@28890|Euryarchaeota	28890|Euryarchaeota	C	Heterodisulfide reductase subunit	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
LZS2_k127_3071224_2	335543.Sfum_1046	4.64e-200	630.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2MR3M@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
LZS2_k127_3071224_10	35754.JNYJ01000089_gene6362	8.461e-19	91.0	COG1765@1|root,COG1765@2|Bacteria,2IFY4@201174|Actinobacteria,4DJDG@85008|Micromonosporales	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
LZS2_k127_3086032_0	1379698.RBG1_1C00001G1816	2.434e-69	261.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
LZS2_k127_3086032_1	344747.PM8797T_07584	4.807e-43	175.0	COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS2_k127_3109282_2	765911.Thivi_4128	4.895e-75	256.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1WZ19@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
LZS2_k127_3109282_7	767817.Desgi_0889	3.439e-51	188.0	COG2267@1|root,COG2267@2|Bacteria,1VDKR@1239|Firmicutes,24YIZ@186801|Clostridia,264S4@186807|Peptococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3109282_12	767817.Desgi_0889	1.038e-28	117.0	COG2267@1|root,COG2267@2|Bacteria,1VDKR@1239|Firmicutes,24YIZ@186801|Clostridia,264S4@186807|Peptococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3109282_0	1123242.JH636434_gene5621	1.427e-176	572.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
LZS2_k127_3109282_8	580332.Slit_0335	9.515e-47	175.0	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,2VSYY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3109282_6	1267005.KB911259_gene3880	4.025e-61	217.0	COG0288@1|root,COG0288@2|Bacteria,1MV1U@1224|Proteobacteria,2VEYE@28211|Alphaproteobacteria,3N6RX@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
LZS2_k127_3109282_9	1121403.AUCV01000002_gene474	2.593e-45	168.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	hom	-	1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19	ko:K00003,ko:K00058,ko:K01754,ko:K04767	ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00017,M00018,M00020,M00570	R00220,R00996,R01513,R01773,R01775	RC00031,RC00087,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3
LZS2_k127_3109282_14	1121904.ARBP01000017_gene5152	2.246e-14	81.0	COG1309@1|root,COG1309@2|Bacteria,4NKU9@976|Bacteroidetes,47MM9@768503|Cytophagia	976|Bacteroidetes	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
LZS2_k127_3109282_10	1232437.KL661972_gene4775	1.583e-43	167.0	COG0500@1|root,COG2226@2|Bacteria,1NNI3@1224|Proteobacteria,4321D@68525|delta/epsilon subdivisions,2WX0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_3109282_5	331678.Cphamn1_1502	1.422e-62	219.0	COG2318@1|root,COG2318@2|Bacteria,1FF6X@1090|Chlorobi	1090|Chlorobi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS2_k127_3109282_1	1366050.N234_10460	1.484e-108	362.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,2VZKC@28216|Betaproteobacteria,1KBNU@119060|Burkholderiaceae	28216|Betaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
LZS2_k127_3109282_11	1249627.D779_2721	8.93e-42	162.0	COG4087@1|root,COG4087@2|Bacteria,1N05K@1224|Proteobacteria,1S9IB@1236|Gammaproteobacteria,1X101@135613|Chromatiales	135613|Chromatiales	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase
LZS2_k127_3109282_3	1569209.BBPH01000003_gene1697	6.147e-72	254.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2TS53@28211|Alphaproteobacteria,2PUTA@265|Paracoccus	28211|Alphaproteobacteria	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
LZS2_k127_3109282_13	759362.KVU_2219	2.971e-15	76.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,2TS53@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
LZS2_k127_3109282_4	1047013.AQSP01000126_gene2741	2.517e-67	239.0	COG0339@1|root,COG0339@2|Bacteria,2NP9Q@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M3	prlC	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
LZS2_k127_3118331_2	566466.NOR53_455	4.138e-19	96.0	2EFI3@1|root,339AJ@2|Bacteria,1N96F@1224|Proteobacteria,1SE0P@1236|Gammaproteobacteria,1J9XG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
LZS2_k127_3118331_1	1089550.ATTH01000001_gene2333	1.754e-33	135.0	COG1595@1|root,COG1595@2|Bacteria,4PF4G@976|Bacteroidetes,1FK4D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_3118331_0	880073.Calab_3409	3.695e-49	187.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	DUF4912,PBP_like_2
LZS2_k127_3121258_3	1001585.MDS_2339	1.045e-09	67.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,1RQ67@1236|Gammaproteobacteria,1YE5T@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA	-	-	ko:K07799,ko:K21135	ko02020,map02020	M00648,M00822	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2.35,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS2_k127_3121258_2	1047013.AQSP01000132_gene1742	1.744e-13	83.0	COG3391@1|root,COG3391@2|Bacteria,2NQ4G@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,TolB_like
LZS2_k127_3121258_0	1382306.JNIM01000001_gene1966	2.438e-179	574.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
LZS2_k127_3121258_1	880073.Calab_1151	7.402e-92	314.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
LZS2_k127_315534_1	555779.Dthio_PD1954	3.147e-27	127.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2M8BJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS2_k127_315534_0	1307761.L21SP2_3292	4.518e-37	156.0	COG5000@1|root,COG5000@2|Bacteria,2J753@203691|Spirochaetes	203691|Spirochaetes	T	Histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_3156350_0	1047013.AQSP01000052_gene2600	1.106e-95	326.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS2_k127_3156350_2	1121430.JMLG01000002_gene1035	1.634e-52	194.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
LZS2_k127_3156350_1	626887.J057_04761	9.04e-82	280.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,464J3@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
LZS2_k127_3156350_3	398767.Glov_2832	1.682e-21	96.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
LZS2_k127_3164754_6	869210.Marky_0784	4.431e-13	70.0	COG1100@1|root,COG1100@2|Bacteria,1WJAD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
LZS2_k127_3164754_2	1125863.JAFN01000001_gene527	4.602e-25	116.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
LZS2_k127_3164754_0	1128421.JAGA01000002_gene120	2.241e-71	257.0	COG0438@1|root,COG0558@1|root,COG0438@2|Bacteria,COG0558@2|Bacteria,2NPRA@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	-	2.4.1.345,2.7.8.5	ko:K00995,ko:K08256	ko00564,ko01100,map00564,map01100	-	R01801,R11702	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000,ko01003	-	GT4	-	CDP-OH_P_transf,Glyco_transf_4,Glycos_transf_1
LZS2_k127_3164754_5	525904.Tter_0763	2.925e-16	92.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
LZS2_k127_3164754_3	1499967.BAYZ01000074_gene2082	8.903e-23	109.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	2.7.11.1,2.7.7.65	ko:K02488,ko:K04757	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	HATPase_c,HATPase_c_2,HisKA,Response_reg
LZS2_k127_3164754_4	1379270.AUXF01000006_gene311	2.135e-16	85.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
LZS2_k127_3164754_1	269799.Gmet_1777	6.747e-57	204.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
LZS2_k127_3186040_1	1254432.SCE1572_07000	1.185e-61	218.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,4307J@68525|delta/epsilon subdivisions,2WV6F@28221|Deltaproteobacteria,2YVCQ@29|Myxococcales	28221|Deltaproteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS2_k127_3186040_0	247490.KSU1_C0202	1.442e-138	449.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflC	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
LZS2_k127_3186040_2	247490.KSU1_C0201	8.571e-44	164.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	nfeD	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
LZS2_k127_3186040_3	1408473.JHXO01000001_gene1949	3.003e-39	157.0	COG3104@1|root,COG3104@2|Bacteria,4NIIT@976|Bacteroidetes,2FR16@200643|Bacteroidia	976|Bacteroidetes	E	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_3189669_0	1304874.JAFY01000005_gene1181	2.125e-195	631.0	COG0480@1|root,COG0480@2|Bacteria,3TA2B@508458|Synergistetes	508458|Synergistetes	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS2_k127_3189669_2	1121405.dsmv_1370	1.864e-84	286.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MIE0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
LZS2_k127_3189669_3	1129794.C427_4062	4.241e-40	154.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,466I2@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
LZS2_k127_3189669_4	476272.RUMHYD_00511	2.611e-34	140.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3XZX0@572511|Blautia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
LZS2_k127_3189669_1	518766.Rmar_2652	6.322e-123	402.0	COG2255@1|root,COG2255@2|Bacteria,4NEB9@976|Bacteroidetes,1FJ1Q@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
LZS2_k127_3189669_5	644966.Tmar_0853	1.539e-22	98.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WCFH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
LZS2_k127_3216699_0	1519464.HY22_07585	3.053e-277	862.0	COG0405@1|root,COG0405@2|Bacteria	2|Bacteria	E	Gamma-glutamyltransferase	ggt_1	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS2_k127_3216699_1	521011.Mpal_0355	3.079e-75	265.0	arCOG08055@1|root,arCOG08055@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_3216699_3	945713.IALB_2435	1.412e-26	113.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
LZS2_k127_3216699_2	945713.IALB_2434	1.202e-28	117.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
LZS2_k127_3217408_3	1122146.AUHP01000010_gene1107	2.091e-09	60.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,3F3WW@33958|Lactobacillaceae	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
LZS2_k127_3217408_2	1131269.AQVV01000017_gene1992	2.618e-62	226.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	xerC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS2_k127_3217408_1	156889.Mmc1_0017	1.257e-65	228.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
LZS2_k127_3217408_0	518766.Rmar_1879	1.032e-68	244.0	COG1220@1|root,COG1220@2|Bacteria,4NFI2@976|Bacteroidetes,1FIQI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
LZS2_k127_3234050_8	331678.Cphamn1_0180	5.851e-39	150.0	COG1028@1|root,COG1028@2|Bacteria,1FDUA@1090|Chlorobi	1090|Chlorobi	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS2_k127_3234050_5	880073.Calab_0619	1.712e-79	275.0	COG0331@1|root,COG0331@2|Bacteria,2NP3V@2323|unclassified Bacteria	2|Bacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15327,ko:K15329,ko:K15355,ko:K15469	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Acyl_transf_1
LZS2_k127_3234050_3	1329516.JPST01000007_gene1526	1.501e-117	386.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli,27BAZ@186824|Thermoactinomycetaceae	91061|Bacilli	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS2_k127_3234050_4	498761.HM1_2161	2.891e-98	331.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
LZS2_k127_3234050_10	373903.Hore_10230	1.43e-19	89.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3WBZP@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
LZS2_k127_3234050_11	742741.HMPREF9475_03797	3.153e-18	91.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,2203E@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
LZS2_k127_3234050_9	399550.Smar_0828	1.424e-34	140.0	COG0105@1|root,arCOG04313@2157|Archaea,2XQEV@28889|Crenarchaeota	28889|Crenarchaeota	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
LZS2_k127_3234050_2	379066.GAU_1645	3.385e-119	390.0	COG0074@1|root,COG0074@2|Bacteria,1ZT20@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
LZS2_k127_3234050_1	1379698.RBG1_1C00001G0475	2.706e-137	446.0	COG0045@1|root,COG0045@2|Bacteria,2NNQA@2323|unclassified Bacteria	2|Bacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009361,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0042709,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261,iPC815.YPO1115,iUMNK88_1353.UMNK88_764,iYO844.BSU16090	ATP-grasp_2,Ligase_CoA
LZS2_k127_3234050_0	1343739.PAP_07605	4.67e-189	599.0	COG2403@1|root,arCOG01229@2157|Archaea,2XVYH@28890|Euryarchaeota,24343@183968|Thermococci	183968|Thermococci	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
LZS2_k127_3234050_7	1279009.ADICEAN_00988	2.137e-42	161.0	COG0615@1|root,COG0615@2|Bacteria,4NNKK@976|Bacteroidetes,47PFX@768503|Cytophagia	976|Bacteroidetes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like
LZS2_k127_3234050_6	671143.DAMO_0267	2.882e-73	259.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
LZS2_k127_335825_2	383372.Rcas_1125	4.564e-30	138.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi,376JU@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_335825_0	1192034.CAP_2649	6.779e-50	194.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YV6N@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
LZS2_k127_335825_1	580332.Slit_2647	1.592e-47	183.0	COG1262@1|root,COG1262@2|Bacteria,1RAMU@1224|Proteobacteria,2VX2U@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,NACHT,TIR_2
LZS2_k127_3368366_1	1121104.AQXH01000001_gene1411	6.021e-54	205.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS2_k127_3368366_2	1379698.RBG1_1C00001G1850	6.177e-53	196.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS2_k127_3368366_0	649638.Trad_1635	2.641e-67	246.0	COG0534@1|root,COG0534@2|Bacteria,1WKWJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG0534 Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
LZS2_k127_3368425_5	373903.Hore_09410	7.085e-43	168.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3WARH@53433|Halanaerobiales	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
LZS2_k127_3368425_4	1379698.RBG1_1C00001G0226	3.25e-48	190.0	COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
LZS2_k127_3368425_0	1121472.AQWN01000003_gene1404	1.175e-129	428.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS2_k127_3368425_1	1120966.AUBU01000015_gene1842	1.65e-115	381.0	COG0540@1|root,COG0540@2|Bacteria,4NFIU@976|Bacteroidetes,47KS2@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS2_k127_3368425_3	1122216.AUHW01000002_gene1766	7.655e-67	234.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4H3ZG@909932|Negativicutes	909932|Negativicutes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
LZS2_k127_3368425_2	945713.IALB_2152	1.354e-69	249.0	COG2309@1|root,COG2309@2|Bacteria	2|Bacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
LZS2_k127_3368425_6	589924.Ferp_1117	9.226e-08	61.0	arCOG11830@1|root,arCOG11830@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3368448_2	913865.DOT_2387	1.045e-31	133.0	2CDHP@1|root,32RXU@2|Bacteria,1VQ7W@1239|Firmicutes,251NF@186801|Clostridia,265N8@186807|Peptococcaceae	186801|Clostridia	S	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
LZS2_k127_3368448_0	485915.Dret_0235	1.348e-127	415.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2M7X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
LZS2_k127_3368448_1	1009370.ALO_03901	4.299e-76	258.0	COG0247@1|root,COG0247@2|Bacteria,1TSC1@1239|Firmicutes,4H6UU@909932|Negativicutes	909932|Negativicutes	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
LZS2_k127_3401435_0	690850.Desaf_1394	6.173e-76	264.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,42Q26@68525|delta/epsilon subdivisions,2WPER@28221|Deltaproteobacteria,2MBP3@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3402544_2	933262.AXAM01000043_gene1195	5.602e-131	430.0	COG1482@1|root,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,42QR1@68525|delta/epsilon subdivisions,2WU24@28221|Deltaproteobacteria,2MMJP@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphomannose isomerase type I	-	-	5.3.1.8,5.4.2.8	ko:K01809,ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818,R01819	RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
LZS2_k127_3402544_1	376619.FTL_0609	1.991e-134	443.0	COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria,1RNFZ@1236|Gammaproteobacteria,461VD@72273|Thiotrichales	72273|Thiotrichales	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS2_k127_3402544_0	335543.Sfum_3591	1.445e-272	846.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WJ0I@28221|Deltaproteobacteria,2MRE4@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	hexose biosynthetic process	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
LZS2_k127_3402544_4	767817.Desgi_1574	1.456e-06	54.0	COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,24939@186801|Clostridia	186801|Clostridia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
LZS2_k127_3402544_3	485915.Dret_1035	2.126e-31	129.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria,2M7Y6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
LZS2_k127_3408759_9	557598.LHK_01836	1.766e-93	310.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,2KQ8K@206351|Neisseriales	206351|Neisseriales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS2_k127_3408759_0	880073.Calab_0944	2.829e-271	847.0	COG0187@1|root,COG0187@2|Bacteria,2NNSN@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
LZS2_k127_3408759_35	398767.Glov_2445	0.0005876	47.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
LZS2_k127_3408759_15	717605.Theco_3756	7.129e-60	220.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,26QB9@186822|Paenibacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
LZS2_k127_3408759_10	379066.GAU_0002	1.236e-83	290.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
LZS2_k127_3408759_4	574087.Acear_0001	4.28e-138	452.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,3WAI7@53433|Halanaerobiales	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS2_k127_3408759_29	349124.Hhal_1228	1.72e-13	70.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1WZNE@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
LZS2_k127_3408759_31	1123226.KB899284_gene3655	1.063e-10	68.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli,26XN0@186822|Paenibacillaceae	91061|Bacilli	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
LZS2_k127_3408759_25	994479.GL877880_gene3980	1.401e-25	107.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4E5Q0@85010|Pseudonocardiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
LZS2_k127_3408759_11	945713.IALB_3204	1.887e-73	270.0	COG0706@1|root,COG0706@2|Bacteria	2|Bacteria	U	membrane insertase activity	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
LZS2_k127_3408759_23	720554.Clocl_4226	8.922e-35	142.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WHR4@541000|Ruminococcaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
LZS2_k127_3408759_7	1064535.MELS_0508	2.544e-97	334.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4H3K8@909932|Negativicutes	909932|Negativicutes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
LZS2_k127_3408759_2	330214.NIDE0362	5.869e-202	647.0	COG0445@1|root,COG0445@2|Bacteria,3J0E9@40117|Nitrospirae	40117|Nitrospirae	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
LZS2_k127_3408759_28	161934.XP_010678688.1	8.707e-17	89.0	COG0357@1|root,2QR3G@2759|Eukaryota,37IW8@33090|Viridiplantae,3GB9N@35493|Streptophyta	35493|Streptophyta	M	Ribosomal RNA small subunit methyltransferase	-	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
LZS2_k127_3408759_34	1242864.D187_009237	2.414e-06	60.0	COG5492@1|root,COG5492@2|Bacteria,1NPYT@1224|Proteobacteria,43C8C@68525|delta/epsilon subdivisions,2X7IS@28221|Deltaproteobacteria,2Z1PI@29|Myxococcales	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PKD
LZS2_k127_3408759_8	1379698.RBG1_1C00001G0199	4.855e-97	325.0	COG1192@1|root,COG1192@2|Bacteria,2NP2C@2323|unclassified Bacteria	2|Bacteria	D	Cobyrinic acid ac-diamide synthase	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS2_k127_3408759_16	1118054.CAGW01000038_gene927	8.866e-56	205.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,26RXG@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the ParB family	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
LZS2_k127_3408759_20	1120985.AUMI01000016_gene1988	5.512e-38	153.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,4H4HE@909932|Negativicutes	909932|Negativicutes	M	Peptidase, M23 family	envC_2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_3408759_27	639282.DEFDS_0128	1.979e-21	99.0	COG1664@1|root,COG1664@2|Bacteria,2GFXX@200930|Deferribacteres	200930|Deferribacteres	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS2_k127_3408759_33	290397.Adeh_1557	2.613e-08	56.0	COG0695@1|root,COG0695@2|Bacteria,1P8SJ@1224|Proteobacteria,42XTX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Glutaredoxin	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
LZS2_k127_3408759_5	1379698.RBG1_1C00001G0201	3.507e-131	426.0	COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria	2|Bacteria	O	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS2_k127_3408759_6	1379698.RBG1_1C00001G0202	1.065e-102	343.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS2_k127_3408759_18	575540.Isop_3542	1.57e-42	178.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,2J513@203682|Planctomycetes	203682|Planctomycetes	G	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
LZS2_k127_3408759_1	1121423.JONT01000015_gene1346	3.6e-238	780.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,2600Y@186807|Peptococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
LZS2_k127_3408759_26	269799.Gmet_3548	2.863e-23	115.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,43T4C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS2_k127_3408759_32	1280941.HY2_00775	5.066e-10	72.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,43XE3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Peptidylprolyl isomerase	prsA	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
LZS2_k127_3408759_21	269799.Gmet_3548	1.654e-36	152.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,43T4C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS2_k127_3408759_22	553385.JEMF01000020_gene3035	2.327e-36	155.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1XICE@135619|Oceanospirillales	135619|Oceanospirillales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
LZS2_k127_3408759_30	498761.HM1_0715	5.991e-11	66.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
LZS2_k127_3408759_13	644282.Deba_2731	2.731e-67	241.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
LZS2_k127_3408759_12	880073.Calab_1944	4.985e-72	252.0	COG2884@1|root,COG2884@2|Bacteria,2NP95@2323|unclassified Bacteria	2|Bacteria	D	ATPases associated with a variety of cellular activities	ftsE	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
LZS2_k127_3408759_19	1123288.SOV_3c01950	1.831e-39	162.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4H36P@909932|Negativicutes	909932|Negativicutes	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
LZS2_k127_3408759_17	1379698.RBG1_1C00001G0315	4.487e-48	188.0	COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria	2|Bacteria	D	Peptidase family M23	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
LZS2_k127_3408759_24	1089550.ATTH01000001_gene2541	7.756e-28	126.0	COG2812@1|root,COG2812@2|Bacteria,4PKEA@976|Bacteroidetes,1FJ1I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
LZS2_k127_3408759_14	697303.Thewi_0107	7.306e-66	235.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,42ETV@68295|Thermoanaerobacterales	186801|Clostridia	S	PSP1 domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
LZS2_k127_3408759_3	643648.Slip_0054	3.883e-151	494.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42JKJ@68298|Syntrophomonadaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
LZS2_k127_3422955_26	1121430.JMLG01000001_gene2158	9.748e-16	81.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,260S5@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
LZS2_k127_3422955_19	1499967.BAYZ01000078_gene990	9.44e-43	167.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
LZS2_k127_3422955_12	667014.Thein_2091	2.334e-79	272.0	COG0020@1|root,COG0020@2|Bacteria,2GH8Y@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
LZS2_k127_3422955_14	1307761.L21SP2_1327	1.215e-60	214.0	COG0233@1|root,COG0233@2|Bacteria,2J6PZ@203691|Spirochaetes	203691|Spirochaetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
LZS2_k127_3422955_9	1379698.RBG1_1C00001G1019	2.924e-94	314.0	COG0528@1|root,COG0528@2|Bacteria,2NNRY@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS06240	AA_kinase
LZS2_k127_3422955_13	880073.Calab_2291	9.26e-76	258.0	COG0264@1|root,COG0264@2|Bacteria,2NP3B@2323|unclassified Bacteria	2|Bacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
LZS2_k127_3422955_11	1122217.KB899574_gene2056	9.896e-85	291.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H1Z4@909932|Negativicutes	909932|Negativicutes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
LZS2_k127_3422955_21	477974.Daud_0331	4.884e-39	149.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,261YG@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS2_k127_3422955_15	635013.TherJR_0331	6.441e-57	202.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,261UG@186807|Peptococcaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
LZS2_k127_3422955_0	237368.SCABRO_00111	8.357e-256	810.0	COG1331@1|root,COG1331@2|Bacteria,2IX0N@203682|Planctomycetes	203682|Planctomycetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	DsbC,GlcNAc_2-epim,Thioredox_DsbH
LZS2_k127_3422955_18	1485545.JQLW01000010_gene1565	4.35e-44	179.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
LZS2_k127_3422955_16	59374.Fisuc_1317	4.474e-56	202.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	lpoB	GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K07337,ko:K21008	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	LpoB
LZS2_k127_3422955_1	32057.KB217483_gene9230	1.728e-243	771.0	COG2217@1|root,COG2217@2|Bacteria,1G11M@1117|Cyanobacteria,1HJK2@1161|Nostocales	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS2_k127_3422955_2	518766.Rmar_2008	3.977e-212	668.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1FJ1P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_3422955_10	1121405.dsmv_3616	9.138e-89	297.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,42PC4@68525|delta/epsilon subdivisions,2WMG6@28221|Deltaproteobacteria,2MJRS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
LZS2_k127_3422955_7	1304874.JAFY01000007_gene2463	9.773e-101	340.0	COG0182@1|root,COG0182@2|Bacteria,3TA3K@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
LZS2_k127_3422955_20	1089553.Tph_c05950	1.029e-41	164.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,42GIM@68295|Thermoanaerobacterales	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
LZS2_k127_3422955_17	572547.Amico_0598	1.356e-51	186.0	COG1490@1|root,COG1490@2|Bacteria,3TB52@508458|Synergistetes	508458|Synergistetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
LZS2_k127_3422955_6	1121472.AQWN01000005_gene2490	5.155e-105	361.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25ZYA@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
LZS2_k127_3422955_22	1463825.JNXC01000036_gene3552	4.731e-35	143.0	COG0328@1|root,COG0406@1|root,COG0328@2|Bacteria,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,4E04U@85010|Pseudonocardiales	201174|Actinobacteria	GL	phosphoglycerate mutase	rnhA	GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	3.1.26.4,3.1.3.73	ko:K02226,ko:K22316	ko00860,ko01100,ko03030,map00860,map01100,map03030	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000,ko03032	-	-	-	His_Phos_1,RVT_3
LZS2_k127_3422955_24	289376.THEYE_A1031	1.369e-26	118.0	COG1579@1|root,COG1579@2|Bacteria,3J0UV@40117|Nitrospirae	40117|Nitrospirae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
LZS2_k127_3422955_3	1254432.SCE1572_27170	9.996e-129	432.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_3422955_8	1379698.RBG1_1C00001G1481	1.126e-98	345.0	COG0358@1|root,COG0358@2|Bacteria,2NNNJ@2323|unclassified Bacteria	2|Bacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
LZS2_k127_3422955_5	868595.Desca_1213	1.275e-113	396.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
LZS2_k127_3422955_28	452471.Aasi_0823	7.481e-06	56.0	COG1286@1|root,COG1286@2|Bacteria,4P9DK@976|Bacteroidetes,47R1Y@768503|Cytophagia	976|Bacteroidetes	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
LZS2_k127_3422955_23	1499967.BAYZ01000073_gene2011	1.247e-29	124.0	COG1610@1|root,COG1610@2|Bacteria,2NPQ9@2323|unclassified Bacteria	2|Bacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
LZS2_k127_3422955_25	1536770.R50345_23490	1.253e-25	116.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli,26RFE@186822|Paenibacillaceae	91061|Bacilli	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
LZS2_k127_3422955_4	880073.Calab_1434	2.251e-120	397.0	COG0484@1|root,COG0484@2|Bacteria,2NNNG@2323|unclassified Bacteria	2|Bacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS2_k127_3422955_30	289376.THEYE_A1758	0.0004631	45.0	COG0443@1|root,COG0443@2|Bacteria,3J0D2@40117|Nitrospirae	40117|Nitrospirae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS2_k127_344530_4	502025.Hoch_6778	8.662e-75	272.0	COG0491@1|root,COG0491@2|Bacteria,1Q2NG@1224|Proteobacteria,4389J@68525|delta/epsilon subdivisions,2X3IZ@28221|Deltaproteobacteria,2YWA6@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_344530_5	485916.Dtox_1076	4.408e-70	246.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,261KY@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
LZS2_k127_344530_9	986075.CathTA2_2247	4.425e-12	74.0	COG2227@1|root,COG2227@2|Bacteria,1VGA5@1239|Firmicutes	1239|Firmicutes	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,TehB
LZS2_k127_344530_1	1168034.FH5T_20555	0.0	1070.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,2FNSJ@200643|Bacteroidia	976|Bacteroidetes	C	CoA binding domain protein	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
LZS2_k127_344530_7	945713.IALB_0147	9.94e-23	115.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
LZS2_k127_344530_10	1379698.RBG1_1C00001G0593	1.596e-08	68.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin_3,DUF11,FlgD_ig
LZS2_k127_344530_0	945713.IALB_0300	0.0	1155.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N,Response_reg,SpoIIE
LZS2_k127_344530_2	945713.IALB_0301	3.538e-248	771.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_344530_8	1408437.JNJN01000026_gene697	3.836e-12	74.0	COG0760@1|root,COG0760@2|Bacteria,1VE2Y@1239|Firmicutes	1239|Firmicutes	M	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_3,SurA_N_3
LZS2_k127_344530_3	382464.ABSI01000010_gene3557	1.32e-105	350.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS2_k127_344530_6	309807.SRU_2672	1.94e-30	136.0	COG1668@1|root,COG1668@2|Bacteria,4NFSZ@976|Bacteroidetes,1FIJ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_3459406_8	880073.Calab_0272	1.637e-18	101.0	COG1649@1|root,COG3023@1|root,COG3391@1|root,COG4412@1|root,COG1649@2|Bacteria,COG3023@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.20,3.4.17.22,3.5.1.28	ko:K01187,ko:K01448,ko:K07752	ko00052,ko00500,ko01100,ko01503,map00052,map00500,map01100,map01503	M00727	R00028,R00801,R00802,R04112,R06087,R06088	RC00028,RC00049,RC00064,RC00077,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036	-	GH31	-	Amidase_2
LZS2_k127_3459406_5	1121957.ATVL01000014_gene1459	1.806e-54	222.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3459406_10	1237149.C900_01254	4.636e-18	101.0	COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria,4NF1M@976|Bacteroidetes	976|Bacteroidetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Peptidase_S8_N
LZS2_k127_3459406_7	1403819.BATR01000011_gene426	9.494e-38	166.0	COG1345@1|root,COG1404@1|root,COG1345@2|Bacteria,COG1404@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
LZS2_k127_3459406_9	459349.CLOAM0602	2.677e-18	102.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.17.22	ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Cellulase,DUF4859,F5_F8_type_C,FlgD_ig
LZS2_k127_3459406_4	1499967.BAYZ01000088_gene5087	8.122e-121	404.0	COG0621@1|root,COG0621@2|Bacteria,2NP2U@2323|unclassified Bacteria	2|Bacteria	J	Uncharacterized protein family UPF0004	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
LZS2_k127_3459406_2	880073.Calab_3776	3.854e-152	494.0	COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
LZS2_k127_3459406_3	448385.sce7277	1.911e-144	469.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PCA@68525|delta/epsilon subdivisions,2WM39@28221|Deltaproteobacteria,2Z0ZC@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_3459406_12	504472.Slin_4425	8.002e-06	54.0	COG4914@1|root,COG4914@2|Bacteria,4NQC4@976|Bacteroidetes,47QAE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3459406_6	1047013.AQSP01000059_gene2096	3.728e-42	158.0	COG0736@1|root,COG0736@2|Bacteria,2NPTD@2323|unclassified Bacteria	2|Bacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7,4.2.1.136	ko:K00997,ko:K17758	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS,Carb_kinase
LZS2_k127_3459406_0	1341151.ASZU01000004_gene585	3.595e-182	587.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,4H9PN@91061|Bacilli,27B6R@186824|Thermoactinomycetaceae	91061|Bacilli	I	AMP-binding enzyme C-terminal domain	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS2_k127_3459406_11	1206725.BAFU01000072_gene6249	5.163e-07	55.0	2BHWJ@1|root,32C0I@2|Bacteria,2IT5X@201174|Actinobacteria,4G3E8@85025|Nocardiaceae	201174|Actinobacteria	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS2_k127_3459406_1	1270196.JCKI01000006_gene2749	3.406e-154	497.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_3462267_1	880073.Calab_1391	8.609e-111	365.0	COG0825@1|root,COG0825@2|Bacteria,2NNVQ@2323|unclassified Bacteria	2|Bacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA,Carboxyl_trans
LZS2_k127_3462267_2	1379698.RBG1_1C00001G1526	4.514e-34	141.0	2CBA8@1|root,30BZT@2|Bacteria,2NR2H@2323|unclassified Bacteria	2|Bacteria	S	Exopolysaccharide biosynthesis protein YbjH	-	-	-	-	-	-	-	-	-	-	-	-	YjbH
LZS2_k127_3462267_0	370438.PTH_2220	7.875e-214	687.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS2_k127_3550232_1	880073.Calab_1720	6.412e-47	182.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
LZS2_k127_3550232_0	1379698.RBG1_1C00001G1003	8.761e-115	392.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
LZS2_k127_3550232_3	926692.AZYG01000004_gene2097	6.87e-12	73.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24RP5@186801|Clostridia,3WAXZ@53433|Halanaerobiales	186801|Clostridia	M	TIGRFAM rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
LZS2_k127_3550232_2	717231.Flexsi_0891	1.279e-17	87.0	COG1792@1|root,COG1792@2|Bacteria,2GFFR@200930|Deferribacteres	200930|Deferribacteres	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
LZS2_k127_3573143_1	234267.Acid_6601	8.668e-51	196.0	COG0265@1|root,COG2203@1|root,COG2208@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria	57723|Acidobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,RibD_C,SpoIIE
LZS2_k127_3573143_0	926567.TheveDRAFT_0030	3.039e-159	511.0	COG4992@1|root,COG4992@2|Bacteria,3TAN5@508458|Synergistetes	508458|Synergistetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_3573143_2	1499967.BAYZ01000013_gene6445	1.409e-48	180.0	COG1748@1|root,COG1748@2|Bacteria,2NNZ1@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lys2	-	1.5.1.10	ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R02315	RC00215,RC00225	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
LZS2_k127_3587781_0	555079.Toce_0820	2.315e-199	650.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,248CT@186801|Clostridia,42ERR@68295|Thermoanaerobacterales	186801|Clostridia	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
LZS2_k127_3587781_1	349124.Hhal_1702	2.108e-29	123.0	COG3359@1|root,COG3359@2|Bacteria,1R5KG@1224|Proteobacteria,1RY3P@1236|Gammaproteobacteria,1WXHZ@135613|Chromatiales	135613|Chromatiales	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
LZS2_k127_3607418_3	795797.C497_10933	1.777e-56	214.0	COG3119@1|root,arCOG02785@2157|Archaea,2Y8G5@28890|Euryarchaeota,241AK@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS2_k127_3607418_10	880073.Calab_2325	1.779e-08	66.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Laminin_G_3,Metallophos,NAGPA,Pur_ac_phosph_N,SLH,VCBS
LZS2_k127_3607418_4	439235.Dalk_1274	8.403e-40	151.0	COG2204@1|root,COG2204@2|Bacteria,1MYSD@1224|Proteobacteria,42SVG@68525|delta/epsilon subdivisions,2WPRW@28221|Deltaproteobacteria,2MK6T@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_3607418_6	177437.HRM2_39230	9.271e-33	140.0	COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2X6GW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
LZS2_k127_3607418_1	96561.Dole_2392	4.655e-142	467.0	COG3850@1|root,COG4191@1|root,COG3850@2|Bacteria,COG4191@2|Bacteria,1P0U1@1224|Proteobacteria,42PTP@68525|delta/epsilon subdivisions,2WJ8U@28221|Deltaproteobacteria,2MIQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_3607418_5	933262.AXAM01000007_gene2051	1.474e-34	138.0	COG2204@1|root,COG2204@2|Bacteria,1N33V@1224|Proteobacteria,42U3U@68525|delta/epsilon subdivisions,2WQ8H@28221|Deltaproteobacteria,2MK2M@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_3607418_0	933262.AXAM01000007_gene2049	4.698e-144	465.0	COG0730@1|root,COG0730@2|Bacteria,1Q05R@1224|Proteobacteria,42NT9@68525|delta/epsilon subdivisions,2WJVB@28221|Deltaproteobacteria,2MJPE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_3607418_2	933262.AXAM01000007_gene2048	4.588e-138	454.0	COG1102@1|root,COG1102@2|Bacteria,1R82J@1224|Proteobacteria,42M5Z@68525|delta/epsilon subdivisions,2WMEJ@28221|Deltaproteobacteria,2MI55@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
LZS2_k127_3607418_7	383372.Rcas_3941	1.701e-28	126.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_3607418_9	269799.Gmet_0243	1.412e-16	93.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
LZS2_k127_3607418_8	1191523.MROS_2237	7.488e-17	96.0	COG0823@1|root,COG4733@1|root,COG0823@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.45	ko:K01201,ko:K13669	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000,ko01003	-	GH30,GT87	-	CBM_6,GT87,PD40
LZS2_k127_3670839_10	1121920.AUAU01000004_gene858	8.752e-31	124.0	COG0119@1|root,COG0119@2|Bacteria,3Y2NJ@57723|Acidobacteria	57723|Acidobacteria	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
LZS2_k127_3670839_1	1121920.AUAU01000004_gene859	1.046e-184	583.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria	57723|Acidobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS2_k127_3670839_12	1033810.HLPCO_000802	2.403e-21	96.0	COG2314@1|root,COG2314@2|Bacteria	2|Bacteria	J	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR,TM2
LZS2_k127_3670839_9	1480694.DC28_14035	1.725e-32	134.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	nnrR	-	-	ko:K01420,ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS2_k127_3670839_5	331678.Cphamn1_0504	1.597e-110	364.0	COG1145@1|root,COG1145@2|Bacteria,1FEGQ@1090|Chlorobi	1090|Chlorobi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
LZS2_k127_3670839_7	290397.Adeh_3190	1.007e-41	159.0	COG4309@1|root,COG4309@2|Bacteria,1P367@1224|Proteobacteria,42TEV@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
LZS2_k127_3670839_3	927658.AJUM01000042_gene1639	2.136e-144	471.0	COG2461@1|root,COG2461@2|Bacteria,4NJQA@976|Bacteroidetes,2FMK7@200643|Bacteroidia,3XKFV@558415|Marinilabiliaceae	976|Bacteroidetes	S	PAS domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
LZS2_k127_3670839_0	706587.Desti_2522	0.0	1093.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria,2MRCW@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Cytochrome C and Quinol oxidase polypeptide I	norZ	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
LZS2_k127_3670839_6	118173.KB235914_gene303	2.503e-63	226.0	COG2846@1|root,COG2846@2|Bacteria,1GBB9@1117|Cyanobacteria	1117|Cyanobacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
LZS2_k127_3670839_8	1123508.JH636442_gene3868	4.654e-41	155.0	COG1959@1|root,COG1959@2|Bacteria,2IZQA@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS2_k127_3670839_4	1173028.ANKO01000244_gene3949	2.323e-112	368.0	COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1HHDU@1150|Oscillatoriales	1117|Cyanobacteria	S	Phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
LZS2_k127_3670839_2	204669.Acid345_2672	9.876e-153	500.0	COG0591@1|root,COG0591@2|Bacteria,3Y4WN@57723|Acidobacteria,2JJVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS2_k127_3670839_11	1121957.ATVL01000011_gene3699	2.001e-27	122.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
LZS2_k127_3695027_0	1249627.D779_2115	9.898e-74	257.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1WXMC@135613|Chromatiales	135613|Chromatiales	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_3695027_4	1173029.JH980292_gene4212	1.319e-17	96.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1H9PH@1150|Oscillatoriales	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_4,TPR_8,Trypsin_2
LZS2_k127_3695027_3	926569.ANT_27010	4.207e-30	125.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS2_k127_3695027_2	909663.KI867150_gene2715	4.431e-36	140.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,2MS6W@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS2_k127_3695027_1	880073.Calab_1349	2.107e-39	154.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS2_k127_3695027_5	517418.Ctha_2056	2.868e-07	61.0	COG0265@1|root,COG0265@2|Bacteria,1FDIE@1090|Chlorobi	1090|Chlorobi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_3703563_1	443143.GM18_2774	8.832e-154	499.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
LZS2_k127_3703563_10	459349.CLOAM0933	1.57e-08	58.0	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
LZS2_k127_3703563_4	290397.Adeh_1687	8.019e-78	271.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2YWUR@29|Myxococcales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS2_k127_3703563_2	880073.Calab_3591	8.555e-125	407.0	COG0180@1|root,COG0180@2|Bacteria,2NNQX@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (W and Y)	trpS	GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS2_k127_3703563_7	243231.GSU1832	3.253e-44	175.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
LZS2_k127_3703563_8	1121405.dsmv_2859	9.048e-42	162.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,2MJWM@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
LZS2_k127_3703563_6	207559.Dde_1958	9.401e-53	195.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,2M9YS@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS2_k127_3703563_3	448385.sce8915	2.393e-82	287.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2YUC9@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_3703563_5	877411.JMMA01000002_gene2231	4.35e-62	232.0	COG0204@1|root,COG0283@1|root,COG0204@2|Bacteria,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WIDU@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
LZS2_k127_3703563_0	1379698.RBG1_1C00001G1225	4.632e-214	683.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
LZS2_k127_3703563_9	1379698.RBG1_1C00001G1136	8.63e-40	162.0	COG2956@1|root,COG2956@2|Bacteria	2|Bacteria	G	lipopolysaccharide metabolic process	ciaB	-	-	ko:K07502,ko:K08309,ko:K19804,ko:K21572	-	-	-	-	ko00000,ko01000,ko01011,ko02000	8.A.46.1,8.A.46.3	GH23	-	SusD-like_3,SusD_RagB,TPR_16,TPR_6,TPR_8
LZS2_k127_370384_2	518766.Rmar_1363	2.78e-124	410.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_370384_11	485915.Dret_1753	8.082e-22	98.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,43B6G@68525|delta/epsilon subdivisions,2WQ1E@28221|Deltaproteobacteria,2MH3Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS2_k127_370384_10	96561.Dole_1704	3.192e-23	113.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_370384_1	518766.Rmar_1523	9.735e-149	488.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1FITT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
LZS2_k127_370384_5	1167006.UWK_02488	1.924e-68	248.0	COG2271@1|root,COG2271@2|Bacteria,1NJTU@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	MA20_01130	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_370384_3	1379698.RBG1_1C00001G0709	2.47e-99	333.0	COG1899@1|root,COG1899@2|Bacteria,2NR8I@2323|unclassified Bacteria	2|Bacteria	O	Deoxyhypusine synthase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
LZS2_k127_370384_7	309799.DICTH_1308	3.818e-49	186.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
LZS2_k127_370384_6	1379698.RBG1_1C00001G0710	6.477e-68	235.0	COG1945@1|root,COG1945@2|Bacteria,2NP74@2323|unclassified Bacteria	2|Bacteria	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
LZS2_k127_370384_8	555088.DealDRAFT_1816	1.039e-46	182.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,42KE0@68298|Syntrophomonadaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
LZS2_k127_370384_0	880073.Calab_1667	4.213e-162	532.0	COG1757@1|root,COG1757@2|Bacteria,2NPD8@2323|unclassified Bacteria	2|Bacteria	C	Na+/H+ antiporter family	nhaC	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
LZS2_k127_370384_12	682795.AciX8_3108	2.463e-08	67.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y719@57723|Acidobacteria,2JKBH@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8,Trans_reg_C
LZS2_k127_370384_9	1123320.KB889562_gene6829	2.334e-31	136.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS2_k127_370384_4	926561.KB900623_gene910	7.927e-98	339.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WBG0@53433|Halanaerobiales	186801|Clostridia	S	PFAM Sodium neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
LZS2_k127_3724515_0	1122169.AREN01000003_gene1189	6.415e-88	306.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,1RYCF@1236|Gammaproteobacteria,1JCD2@118969|Legionellales	118969|Legionellales	U	Glutamate-cysteine ligase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
LZS2_k127_3760323_1	880073.Calab_1356	1.282e-145	481.0	COG1305@1|root,COG1305@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	TIG,Transglut_core
LZS2_k127_3760323_6	671143.DAMO_0301	2.587e-48	195.0	COG0457@1|root,COG4745@1|root,COG0457@2|Bacteria,COG4745@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2,TPR_2,TPR_8
LZS2_k127_3760323_5	518766.Rmar_0129	8.36e-73	252.0	COG1657@1|root,COG1657@2|Bacteria,4NFMT@976|Bacteroidetes,1FJ7Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
LZS2_k127_3760323_4	1191523.MROS_1086	1.622e-77	294.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3760323_9	945713.IALB_0311	8.59e-11	75.0	COG0457@1|root,COG0457@2|Bacteria	945713.IALB_0311|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3760323_0	880073.Calab_1878	4.545e-167	536.0	2CD20@1|root,2Z7SQ@2|Bacteria,2NNUF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3760323_7	861299.J421_3007	1.568e-24	104.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3760323_10	246194.CHY_1108	2.432e-08	64.0	COG1266@1|root,COG1266@2|Bacteria,1UUMR@1239|Firmicutes,25CF0@186801|Clostridia,42GZJ@68295|Thermoanaerobacterales	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS2_k127_3760323_8	877455.Metbo_2172	1.336e-23	109.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,23NYH@183925|Methanobacteria	183925|Methanobacteria	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS2_k127_3760323_3	485916.Dtox_3771	8.671e-103	353.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
LZS2_k127_3760323_2	370438.PTH_0909	7.512e-139	449.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,264Q7@186807|Peptococcaceae	186801|Clostridia	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
LZS2_k127_376576_2	290397.Adeh_4128	7.944e-10	60.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS2_k127_376576_1	626939.HMPREF9443_02039	1.108e-126	419.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4H2N1@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
LZS2_k127_376576_0	883.DvMF_1864	1.603e-195	625.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,42MPY@68525|delta/epsilon subdivisions,2WJ2V@28221|Deltaproteobacteria,2M7Y6@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	belongs to the CobB CobQ family	pta	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1035	AAA_26,DRTGG,PTA_PTB
LZS2_k127_3767889_6	909663.KI867150_gene1473	5.318e-26	109.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,42PHV@68525|delta/epsilon subdivisions,2WKDZ@28221|Deltaproteobacteria,2MRBN@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	ATPase MipZ	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
LZS2_k127_3767889_7	1047013.AQSP01000081_gene98	6.979e-15	80.0	2BJ6B@1|root,32DFP@2|Bacteria,2NRWM@2323|unclassified Bacteria	2|Bacteria	S	Family of unknown function (DUF5320)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5320
LZS2_k127_3767889_3	404589.Anae109_3084	3.53e-66	249.0	2C6TZ@1|root,32RHS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3767889_5	1379698.RBG1_1C00001G0781	2.515e-47	174.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
LZS2_k127_3767889_1	1379698.RBG1_1C00001G0780	8.99e-129	420.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
LZS2_k127_3767889_2	1379698.RBG1_1C00001G0779	1.402e-98	336.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
LZS2_k127_3767889_0	1379698.RBG1_1C00001G1080	4.698e-165	548.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
LZS2_k127_3767889_4	1122134.KB893650_gene1142	4.023e-52	192.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1PM1H@1224|Proteobacteria,1RUN8@1236|Gammaproteobacteria,1XQN3@135619|Oceanospirillales	135619|Oceanospirillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_3793475_1	234267.Acid_7439	5.702e-74	254.0	COG1215@1|root,COG1215@2|Bacteria,3Y5K6@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_3793475_10	273526.SMDB11_2149	4.44e-09	69.0	COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,1RRAJ@1236|Gammaproteobacteria,40218@613|Serratia	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	wzx	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS2_k127_3793475_0	240016.ABIZ01000001_gene5365	4.187e-77	271.0	COG1524@1|root,COG1524@2|Bacteria,46XAN@74201|Verrucomicrobia,2IV7D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_3793475_8	1121448.DGI_1959	2.523e-23	113.0	COG0489@1|root,COG0489@2|Bacteria,1MZ64@1224|Proteobacteria,432Z4@68525|delta/epsilon subdivisions,2WXW1@28221|Deltaproteobacteria,2MDQQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	AAA domain	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31
LZS2_k127_3793475_5	1232410.KI421413_gene654	4.58e-66	235.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,43SAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	SMART AAA ATPase	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
LZS2_k127_3793475_9	1232410.KI421418_gene2330	2.361e-14	86.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WN1C@28221|Deltaproteobacteria,43S7E@69541|Desulfuromonadales	28221|Deltaproteobacteria	DM	Chain length determinant protein	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
LZS2_k127_3793475_7	909663.KI867150_gene2273	4.976e-27	122.0	COG1596@1|root,COG1596@2|Bacteria,1R6M3@1224|Proteobacteria,42SBA@68525|delta/epsilon subdivisions,2WPHA@28221|Deltaproteobacteria,2MS2V@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Polysaccharide biosynthesis export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
LZS2_k127_3793475_4	1047013.AQSP01000112_gene393	1.215e-67	237.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	cpsE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3,STAS
LZS2_k127_3793475_2	1379698.RBG1_1C00001G1248	1.633e-70	251.0	COG1899@1|root,COG1899@2|Bacteria,2NP1S@2323|unclassified Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3793475_3	1379698.RBG1_1C00001G1249	5.822e-70	247.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
LZS2_k127_3793475_6	1125863.JAFN01000001_gene535	2.884e-39	155.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_3794229_1	706587.Desti_4984	2.359e-11	68.0	COG1413@1|root,COG3634@1|root,COG1413@2|Bacteria,COG3634@2|Bacteria	2|Bacteria	C	alkyl hydroperoxide reductase activity	ahpF	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.8.1.9	ko:K00384,ko:K03387	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
LZS2_k127_3794229_0	1379698.RBG1_1C00001G0776	9.721e-163	524.0	COG2864@1|root,COG2864@2|Bacteria,2NNNM@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b subunit of formate dehydrogenase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
LZS2_k127_3827060_3	365046.Rta_18660	3.418e-13	83.0	COG3452@1|root,COG4191@1|root,COG3452@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,4ABE0@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	fixL	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9
LZS2_k127_3827060_1	694427.Palpr_2171	3.052e-66	253.0	COG2199@1|root,COG2203@1|root,COG3829@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,4NI65@976|Bacteroidetes,2FRZ7@200643|Bacteroidia,22YG2@171551|Porphyromonadaceae	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_9,PocR,TPR_12,TPR_8
LZS2_k127_3827060_0	56780.SYN_01953	1.275e-70	245.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS2_k127_3827060_2	523791.Kkor_1008	1.005e-19	104.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1S07F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
LZS2_k127_388254_5	1232410.KI421412_gene323	4.269e-107	355.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS2_k127_388254_2	926550.CLDAP_34670	9.153e-148	480.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
LZS2_k127_388254_0	1121920.AUAU01000006_gene293	0.0	1053.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y3BP@57723|Acidobacteria	57723|Acidobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
LZS2_k127_388254_6	511051.CSE_01380	1.271e-20	97.0	COG2461@1|root,COG2461@2|Bacteria	2|Bacteria	P	Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_10,PAS_4
LZS2_k127_388254_3	886293.Sinac_5561	7.493e-137	449.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_388254_4	886293.Sinac_5560	7.128e-133	441.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	ymxG	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_388254_1	1499683.CCFF01000013_gene324	3.82e-224	703.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
LZS2_k127_388254_7	1365176.N186_02820	1.903e-12	76.0	COG2511@1|root,arCOG01719@2157|Archaea,2XPPH@28889|Crenarchaeota	28889|Crenarchaeota	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate	gatE	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.7	ko:K03330	ko00970,ko01100,map00970,map01100	-	R03905	RC00010	ko00000,ko00001,ko01000	-	-	-	GAD,GatB_N,GatB_Yqey
LZS2_k127_3891867_0	575540.Isop_3282	0.0	1069.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
LZS2_k127_3891867_1	573413.Spirs_3993	1.605e-39	161.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	tnp3503b	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Transposase_mut
LZS2_k127_3910284_12	1047013.AQSP01000111_gene1673	1.901e-19	91.0	COG0615@1|root,COG0615@2|Bacteria,2NPMA@2323|unclassified Bacteria	2|Bacteria	IM	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.39,2.7.7.70	ko:K00980,ko:K03272	ko00540,ko00564,ko01100,map00540,map00564,map01100	M00064	R00856,R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CN_hydrolase,CTP_transf_like,PfkB
LZS2_k127_3910284_7	290397.Adeh_2611	7.547e-56	208.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
LZS2_k127_3910284_8	365046.Rta_01890	1.135e-46	182.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,4ACYJ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS2_k127_3910284_1	1379698.RBG1_1C00001G1033	7.475e-157	517.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA	-	-	ko:K02021,ko:K06147,ko:K06148,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_3910284_15	50960.LS81_01955	0.0008268	51.0	COG0859@1|root,COG0859@2|Bacteria,1Q9DT@1224|Proteobacteria,42ZYQ@68525|delta/epsilon subdivisions,2YRTP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
LZS2_k127_3910284_14	111780.Sta7437_2031	0.0004714	52.0	COG0859@1|root,COG0859@2|Bacteria,1G0KB@1117|Cyanobacteria,3VIMS@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
LZS2_k127_3910284_0	1379698.RBG1_1C00001G0646	3.946e-276	870.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS2_k127_3910284_11	1379698.RBG1_1C00001G0647	6.899e-21	98.0	COG0071@1|root,COG0071@2|Bacteria,2NRQT@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS2_k127_3910284_10	309799.DICTH_0563	7.308e-25	120.0	COG0392@1|root,COG5305@1|root,COG0392@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM,PMT_2
LZS2_k127_3910284_6	1047013.AQSP01000084_gene768	5.584e-67	239.0	COG1801@1|root,COG1801@2|Bacteria,2NPDU@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS2_k127_3910284_9	574087.Acear_1124	3.296e-26	122.0	COG0392@1|root,COG0392@2|Bacteria,1TSAD@1239|Firmicutes,25NQB@186801|Clostridia,3WC37@53433|Halanaerobiales	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_3910284_2	671143.DAMO_0838	3.904e-102	341.0	COG1131@1|root,COG1131@2|Bacteria,2NNKB@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ccmA	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
LZS2_k127_3910284_5	1499967.BAYZ01000095_gene4169	3.41e-77	269.0	COG1277@1|root,COG1277@2|Bacteria,2NPGK@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
LZS2_k127_3910284_3	1499967.BAYZ01000095_gene4168	7.218e-92	321.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
LZS2_k127_3910284_13	1267535.KB906767_gene5088	2.262e-17	95.0	2ANCT@1|root,31DBC@2|Bacteria,3Y69A@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
LZS2_k127_3910284_4	1499967.BAYZ01000068_gene1969	7.44e-82	284.0	COG2006@1|root,COG2006@2|Bacteria,2NPI6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_3910591_1	565045.NOR51B_1793	1.31e-31	127.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1J4G5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
LZS2_k127_3910591_0	2325.TKV_c05750	2.65e-132	437.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,42EZN@68295|Thermoanaerobacterales	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
LZS2_k127_3918426_4	1385514.N782_12390	0.0002344	52.0	28NT3@1|root,2ZBRV@2|Bacteria,1V1C2@1239|Firmicutes,4HFYQ@91061|Bacilli,2YAMT@289201|Pontibacillus	91061|Bacilli	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
LZS2_k127_3918426_0	1047013.AQSP01000130_gene1847	2.237e-131	441.0	COG4232@1|root,COG4232@2|Bacteria,2NPKJ@2323|unclassified Bacteria	2|Bacteria	CO	Protein of unknown function, DUF255	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
LZS2_k127_3918426_1	439235.Dalk_0814	1.393e-72	254.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2MJ7B@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
LZS2_k127_3918426_3	449673.BACSTE_01319	2.13e-36	153.0	COG0438@1|root,COG0438@2|Bacteria,4NM38@976|Bacteroidetes,2FNUT@200643|Bacteroidia,4ANIE@815|Bacteroidaceae	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_3918426_5	153948.NAL212_1682	0.0002488	47.0	2AEYD@1|root,314WA@2|Bacteria,1PUU4@1224|Proteobacteria,2WAXG@28216|Betaproteobacteria,373NK@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398
LZS2_k127_3919042_1	1499967.BAYZ01000076_gene815	1.387e-60	218.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_3919042_3	1499967.BAYZ01000118_gene3276	3.014e-14	86.0	COG1409@1|root,COG4916@1|root,COG1409@2|Bacteria,COG4916@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	GUN4,TIR_2,WD40
LZS2_k127_3919042_0	880073.Calab_3266	9.302e-180	576.0	COG1055@1|root,COG1055@2|Bacteria,2NQJ3@2323|unclassified Bacteria	2|Bacteria	P	Putative citrate transport	arsB	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
LZS2_k127_3919042_5	1124780.ANNU01000062_gene578	2.21e-08	64.0	COG0500@1|root,COG2226@2|Bacteria,4NJZ2@976|Bacteroidetes	976|Bacteroidetes	Q	Ubiquinone biosynthesis methyltransferase UbiE	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
LZS2_k127_3919042_2	715451.ambt_03605	7.697e-27	126.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
LZS2_k127_3930661_0	1191523.MROS_1891	6.305e-189	627.0	COG0729@1|root,COG0823@1|root,COG0729@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	treP	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,PD40
LZS2_k127_3930661_1	243231.GSU2915	1.425e-86	304.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_3930661_5	660470.Theba_0226	3.872e-18	98.0	COG1404@1|root,COG1520@1|root,COG4412@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG4412@2|Bacteria,2GED2@200918|Thermotogae	200918|Thermotogae	O	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3930661_2	1254432.SCE1572_01775	6.06e-72	256.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
LZS2_k127_3930661_3	880073.Calab_0059	8.303e-68	245.0	COG0673@1|root,COG0673@2|Bacteria,2NQ2X@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	ycjS	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_3930661_4	1379698.RBG1_1C00001G0380	2.19e-29	129.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS2_k127_3952076_0	945713.IALB_2157	4.538e-284	889.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	oliA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	OPT
LZS2_k127_3952076_7	1168034.FH5T_19885	1.132e-57	217.0	COG1524@1|root,COG1524@2|Bacteria,4PKSD@976|Bacteroidetes,2FVX7@200643|Bacteroidia	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Phosphodiest
LZS2_k127_3952076_10	215803.DB30_2423	2.648e-10	72.0	COG1404@1|root,COG3291@1|root,COG3509@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG3509@2|Bacteria,1MU3S@1224|Proteobacteria,42N7D@68525|delta/epsilon subdivisions,2WKJS@28221|Deltaproteobacteria,2YZ9E@29|Myxococcales	28221|Deltaproteobacteria	OQ	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,Big_3_3,Inhibitor_I9,Peptidase_S8
LZS2_k127_3952076_5	398579.Spea_2388	1.23e-142	469.0	COG3104@1|root,COG3104@2|Bacteria,1R5E8@1224|Proteobacteria,1RQR0@1236|Gammaproteobacteria,2QA3H@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_3952076_3	880073.Calab_2857	3.809e-160	535.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	DUF2808,Peptidase_S46
LZS2_k127_3952076_6	565033.GACE_1334	6.99e-58	206.0	COG1528@1|root,arCOG01095@2157|Archaea,2XXEN@28890|Euryarchaeota,2472B@183980|Archaeoglobi	183980|Archaeoglobi	P	Ferritin-like domain	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
LZS2_k127_3952076_4	1120973.AQXL01000118_gene459	9.041e-153	498.0	COG0114@1|root,COG0114@2|Bacteria,1UHPH@1239|Firmicutes,4HA6P@91061|Bacilli,2792G@186823|Alicyclobacillaceae	91061|Bacilli	C	Fumarase C C-terminus	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS2_k127_3952076_11	1469607.KK073768_gene1778	2.954e-09	69.0	COG4932@1|root,COG4932@2|Bacteria,1GIGN@1117|Cyanobacteria,1HKKY@1161|Nostocales	1117|Cyanobacteria	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
LZS2_k127_3952076_2	1191523.MROS_1530	1.068e-226	722.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
LZS2_k127_3952076_8	882086.SacxiDRAFT_1887	7.048e-35	152.0	COG1807@1|root,COG1807@2|Bacteria,2IEB9@201174|Actinobacteria,4E27D@85010|Pseudonocardiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3952076_12	795359.TOPB45_1046	0.0006003	48.0	2ECCP@1|root,336AZ@2|Bacteria,2GHY5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Rho termination factor, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
LZS2_k127_3952076_9	697281.Mahau_1960	3.094e-24	111.0	COG0500@1|root,COG2226@2|Bacteria,1V6QV@1239|Firmicutes,24JPQ@186801|Clostridia,42HD2@68295|Thermoanaerobacterales	186801|Clostridia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
LZS2_k127_3964315_2	483219.LILAB_26470	5.539e-07	52.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTUC@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
LZS2_k127_3964315_0	290397.Adeh_1019	3.641e-95	327.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42SYF@68525|delta/epsilon subdivisions,2WPNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
LZS2_k127_3964315_1	323261.Noc_1420	1.471e-93	324.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1S1F9@1236|Gammaproteobacteria,1X1BJ@135613|Chromatiales	135613|Chromatiales	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
LZS2_k127_3969273_15	234267.Acid_3807	1.932e-15	86.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_3969273_7	1267535.KB906767_gene4343	1.791e-75	271.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JM41@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_3969273_6	1047013.AQSP01000042_gene408	1.838e-77	274.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
LZS2_k127_3969273_3	880073.Calab_1156	1.394e-93	313.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_3969273_11	1304874.JAFY01000002_gene145	3.334e-35	151.0	COG1538@1|root,COG1538@2|Bacteria,3TAY7@508458|Synergistetes	508458|Synergistetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS2_k127_3969273_12	880073.Calab_2427	1.36e-30	128.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS2_k127_3969273_13	880073.Calab_2425	6.558e-18	88.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS2_k127_3969273_16	313606.M23134_04329	1.197e-14	79.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,47RSB@768503|Cytophagia	976|Bacteroidetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
LZS2_k127_3969273_9	880073.Calab_2424	2.323e-57	210.0	COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS2_k127_3969273_14	1379698.RBG1_1C00001G1368	6.805e-18	98.0	COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria	2|Bacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
LZS2_k127_3969273_10	880073.Calab_1556	7.116e-49	186.0	COG2067@1|root,COG2067@2|Bacteria,2NR34@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_3969273_5	880073.Calab_2959	1.204e-79	299.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
LZS2_k127_3969273_1	378806.STAUR_5445	5.856e-129	420.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2YU5K@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS2_k127_3969273_2	331678.Cphamn1_1695	6.825e-119	391.0	COG0444@1|root,COG0444@2|Bacteria,1FDSN@1090|Chlorobi	1090|Chlorobi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS2_k127_3969273_8	880072.Desac_2878	3.131e-72	257.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_3969273_4	1519464.HY22_02230	1.349e-85	295.0	COG0601@1|root,COG0601@2|Bacteria,1FDDB@1090|Chlorobi	1090|Chlorobi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_3969273_0	1284352.AOIG01000015_gene4234	6.117e-168	539.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,26RUP@186822|Paenibacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS2_k127_3996406_9	97138.C820_02553	2.814e-47	184.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,36F6R@31979|Clostridiaceae	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
LZS2_k127_3996406_10	1123057.P872_01485	1.671e-09	70.0	COG2244@1|root,COG2244@2|Bacteria,4NMZI@976|Bacteroidetes,47VDD@768503|Cytophagia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS2_k127_3996406_1	880073.Calab_0614	5.218e-139	452.0	COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS2_k127_3996406_3	880073.Calab_3419	9.528e-118	391.0	COG1088@1|root,COG1088@2|Bacteria,2NNRC@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46,4.2.1.76	ko:K01710,ko:K12450	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R00293,R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
LZS2_k127_3996406_7	56780.SYN_00576	1.7e-65	226.0	COG1898@1|root,COG1898@2|Bacteria,1RGRQ@1224|Proteobacteria,42RZA@68525|delta/epsilon subdivisions,2WNBP@28221|Deltaproteobacteria,2MRPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	WxcM-like, C-terminal	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
LZS2_k127_3996406_0	1177928.TH2_11419	8.26e-148	479.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2JPVB@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS2_k127_3996406_6	679926.Mpet_1407	2.119e-73	258.0	COG1089@1|root,arCOG01373@2157|Archaea,2XUVY@28890|Euryarchaeota	28890|Euryarchaeota	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	1.1.1.281,4.2.1.47	ko:K01711,ko:K15856	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888,R03397,R03399	RC00182,RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS2_k127_3996406_2	1047013.AQSP01000138_gene1042	2.11e-132	429.0	COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	wcbK	-	1.1.1.281,4.2.1.47	ko:K01711,ko:K15856	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888,R03397,R03399	RC00182,RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS2_k127_3996406_4	744872.Spica_2145	1.584e-104	356.0	COG1055@1|root,COG1055@2|Bacteria,2J6QU@203691|Spirochaetes	203691|Spirochaetes	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
LZS2_k127_3996406_8	264732.Moth_0883	2.079e-55	203.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,42G12@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
LZS2_k127_3996406_5	177439.DP3015	2.049e-77	269.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2MIHH@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS2_k127_401871_2	1379698.RBG1_1C00001G1498	1.676e-29	131.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin,Thioredoxin_7
LZS2_k127_401871_1	1232410.KI421412_gene151	2.409e-76	265.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,42PP6@68525|delta/epsilon subdivisions,2WJN2@28221|Deltaproteobacteria,43TRT@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
LZS2_k127_401871_0	1121918.ARWE01000001_gene1254	1.388e-116	388.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43S50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
LZS2_k127_4033069_0	1379698.RBG1_1C00001G0383	1.355e-62	231.0	COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_4033069_1	1003200.AXXA_23560	2.1e-41	157.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,3T3TE@506|Alcaligenaceae	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
LZS2_k127_4033069_5	1408418.JNJH01000020_gene967	0.0002561	51.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2JV8U@204441|Rhodospirillales	204441|Rhodospirillales	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS2_k127_4033069_2	459349.CLOAM0631	5.068e-22	112.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
LZS2_k127_4033069_4	1530186.JQEY01000001_gene893	5.652e-05	54.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS2_k127_4048876_7	459349.CLOAM0582	4.256e-14	73.0	COG1572@1|root,COG3391@1|root,COG4412@1|root,COG4733@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	3.4.21.96	ko:K01361,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	F5_F8_type_C,Glucosaminidase,SLH
LZS2_k127_4048876_6	1048983.EL17_12095	2.495e-19	96.0	COG0110@1|root,COG0110@2|Bacteria,4NRD8@976|Bacteroidetes,47PJX@768503|Cytophagia	976|Bacteroidetes	S	Acetyltransferase (Isoleucine patch superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
LZS2_k127_4048876_3	56780.SYN_01146	5.779e-145	468.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42M0R@68525|delta/epsilon subdivisions,2WJE6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_4048876_8	396588.Tgr7_2385	6.547e-14	76.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,1SJ0G@1236|Gammaproteobacteria,1X1K5@135613|Chromatiales	135613|Chromatiales	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS2_k127_4048876_2	402777.KB235906_gene358	7.194e-151	496.0	COG1020@1|root,COG1020@2|Bacteria,1GQ70@1117|Cyanobacteria,1HETZ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
LZS2_k127_4048876_4	1191523.MROS_0021	7.948e-100	342.0	COG3104@1|root,COG3104@2|Bacteria	2|Bacteria	E	oligopeptide transport	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	MFS_1,PTR2
LZS2_k127_4048876_1	1244869.H261_06576	5.738e-179	580.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,2JRZP@204441|Rhodospirillales	204441|Rhodospirillales	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
LZS2_k127_4048876_5	596152.DesU5LDRAFT_2801	4.652e-29	119.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MGUH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS2_k127_4048876_9	382464.ABSI01000011_gene2833	1.394e-09	70.0	COG3595@1|root,COG3595@2|Bacteria,46W0J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
LZS2_k127_4048876_0	290397.Adeh_1020	0.0	1123.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTUC@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
LZS2_k127_4054208_3	765869.BDW_01320	9.094e-53	189.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2MSV0@213481|Bdellovibrionales,2WIY8@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
LZS2_k127_4054208_0	247490.KSU1_C1332	2.08e-125	410.0	COG1180@1|root,COG1180@2|Bacteria,2IYWA@203682|Planctomycetes	203682|Planctomycetes	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS2_k127_4054208_4	1089548.KI783301_gene593	4.265e-47	180.0	COG1028@1|root,COG1028@2|Bacteria,1TPHT@1239|Firmicutes,4IQF2@91061|Bacilli	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS2_k127_4054208_8	518766.Rmar_0834	9.211e-10	70.0	COG0558@1|root,COG0558@2|Bacteria,4NIC4@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
LZS2_k127_4054208_5	1382359.JIAL01000001_gene2816	9.991e-44	166.0	COG0720@1|root,COG0720@2|Bacteria,3Y4K2@57723|Acidobacteria,2JJD0@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM 6-pyruvoyl tetrahydropterin	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
LZS2_k127_4054208_7	290318.Cvib_1081	4.816e-19	92.0	COG0720@1|root,COG0720@2|Bacteria,1FE35@1090|Chlorobi	1090|Chlorobi	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
LZS2_k127_4054208_2	1121939.L861_18550	8.661e-69	243.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,1RMQM@1236|Gammaproteobacteria,1XIJW@135619|Oceanospirillales	135619|Oceanospirillales	H	catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
LZS2_k127_4054208_6	621372.ACIH01000090_gene2956	3.724e-43	162.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli,26QCA@186822|Paenibacillaceae	91061|Bacilli	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS2_k127_4054208_1	1121439.dsat_2288	3.229e-73	253.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria,2M92B@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS2_k127_4094072_1	378806.STAUR_1174	3.398e-37	154.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2YUQ9@29|Myxococcales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
LZS2_k127_4094072_2	1280685.AUKC01000019_gene358	2.148e-28	124.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,4BX70@830|Butyrivibrio	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS2_k127_4094072_0	1379698.RBG1_1C00001G1441	2.957e-237	745.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS2_k127_4134460_8	1444306.JFZC01000004_gene1682	7.675e-16	88.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26NNZ@186821|Sporolactobacillaceae	91061|Bacilli	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
LZS2_k127_4134460_2	1244083.CSUNSWCD_1229	1.718e-132	444.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1R5RS@1224|Proteobacteria,42M3K@68525|delta/epsilon subdivisions,2YN6E@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	PFAM biotin lipoyl attachment domain-containing protein	pycB	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
LZS2_k127_4134460_3	891968.Anamo_2039	4.551e-130	425.0	COG1883@1|root,COG1883@2|Bacteria,3T9TE@508458|Synergistetes	508458|Synergistetes	C	TIGRFAM sodium ion-translocating decarboxylase, beta subunit	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
LZS2_k127_4134460_0	518766.Rmar_0629	1.105e-224	734.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
LZS2_k127_4134460_6	313612.L8106_09901	4.502e-31	132.0	COG1045@1|root,COG1045@2|Bacteria,1G522@1117|Cyanobacteria,1HBAT@1150|Oscillatoriales	1117|Cyanobacteria	E	Serine acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
LZS2_k127_4134460_5	909663.KI867150_gene2281	8.599e-66	234.0	COG2755@1|root,COG2755@2|Bacteria,1RKNW@1224|Proteobacteria,42SMH@68525|delta/epsilon subdivisions,2WPP0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4134460_1	316067.Geob_2951	4.169e-171	552.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ00@28221|Deltaproteobacteria,43UQW@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS2_k127_4134460_4	909663.KI867150_gene1592	1.759e-90	308.0	COG0171@1|root,COG0171@2|Bacteria,1QHZ4@1224|Proteobacteria,42QD8@68525|delta/epsilon subdivisions,2WMK9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
LZS2_k127_4134460_7	933262.AXAM01000037_gene876	1.334e-21	97.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,42VU0@68525|delta/epsilon subdivisions,2WRU6@28221|Deltaproteobacteria,2MP8W@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS2_k127_4134460_9	192952.MM_0613	1.626e-07	53.0	COG0037@1|root,arCOG15275@2157|Archaea	2157|Archaea	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4192793_2	644282.Deba_2866	1.841e-54	203.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_4192793_1	440512.C211_16630	1.794e-60	225.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
LZS2_k127_4192793_5	1121346.KB899858_gene329	4.444e-07	61.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,26RPS@186822|Paenibacillaceae	91061|Bacilli	S	Protein conserved in bacteria	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
LZS2_k127_4192793_3	1191523.MROS_0370	4.328e-28	119.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
LZS2_k127_4192793_4	906968.Trebr_0974	1.135e-10	68.0	COG5652@1|root,COG5652@2|Bacteria,2J890@203691|Spirochaetes	203691|Spirochaetes	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
LZS2_k127_4192793_0	936572.HMPREF1148_0833	1.117e-115	384.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4H20Q@909932|Negativicutes	909932|Negativicutes	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
LZS2_k127_4218118_3	1340493.JNIF01000003_gene3780	9.36e-37	152.0	COG0142@1|root,COG0142@2|Bacteria,3Y2VJ@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS2_k127_4218118_5	1406840.Q763_00165	1.4e-26	115.0	COG1510@1|root,COG1510@2|Bacteria,4NQPD@976|Bacteroidetes,1I39Q@117743|Flavobacteriia,2NUJ5@237|Flavobacterium	976|Bacteroidetes	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,MarR_2,TrmB
LZS2_k127_4218118_4	522772.Dacet_1660	3.829e-33	135.0	COG0791@1|root,COG3087@1|root,COG0791@2|Bacteria,COG3087@2|Bacteria,2GFMA@200930|Deferribacteres	200930|Deferribacteres	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SPOR
LZS2_k127_4218118_0	1382304.JNIL01000001_gene3280	1.179e-260	825.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,277X4@186823|Alicyclobacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
LZS2_k127_4218118_1	1121930.AQXG01000009_gene298	1.267e-151	488.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,1INYF@117747|Sphingobacteriia	976|Bacteroidetes	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_4218118_2	246194.CHY_1607	1.414e-107	357.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,24C0I@186801|Clostridia,42HWH@68295|Thermoanaerobacterales	186801|Clostridia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_4249735_6	880073.Calab_3385	2.549e-14	78.0	COG2204@1|root,COG2204@2|Bacteria,2NQDH@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	fhlA	-	-	ko:K03413,ko:K13589	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00512	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_4249735_3	945713.IALB_2930	2.042e-52	200.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4249735_1	880073.Calab_3649	1.739e-102	356.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2NP1D@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	CP_0155	-	-	ko:K08307,ko:K12204	-	-	-	-	ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1	-	-	LysM,SLT,T4SS_TraI
LZS2_k127_4249735_4	509191.AEDB02000052_gene1363	2.12e-35	151.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,3WN7V@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
LZS2_k127_4249735_5	1408424.JHYI01000004_gene3377	2.021e-15	89.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
LZS2_k127_4249735_2	338963.Pcar_1292	6.279e-60	214.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,43SE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Formyl transferase	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
LZS2_k127_4249735_0	1123371.ATXH01000013_gene1529	5.368e-107	355.0	COG0152@1|root,COG0152@2|Bacteria,2GH07@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
LZS2_k127_4307678_2	1156937.MFUM_310016	5.22e-61	226.0	COG0635@1|root,COG0635@2|Bacteria,46STN@74201|Verrucomicrobia,37FV5@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
LZS2_k127_4307678_3	1379698.RBG1_1C00001G0425	1.98e-60	215.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
LZS2_k127_4307678_0	880073.Calab_1874	3.485e-259	812.0	COG0481@1|root,COG0481@2|Bacteria,2NNXG@2323|unclassified Bacteria	2|Bacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
LZS2_k127_4307678_5	1379698.RBG1_1C00001G0229	1.221e-05	55.0	2BIY5@1|root,32D6E@2|Bacteria,2NRW7@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4307678_4	697303.Thewi_1540	6.864e-39	151.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,42GJ3@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM Endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS2_k127_4307678_1	1379698.RBG1_1C00001G0688	9.087e-250	782.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
LZS2_k127_4315020_1	523791.Kkor_2608	1.664e-67	237.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,1S82H@1236|Gammaproteobacteria,1XJE4@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
LZS2_k127_4315020_2	706587.Desti_0283	1.99e-27	116.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_4315020_0	1121439.dsat_1460	1.552e-124	414.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
LZS2_k127_4315020_4	706587.Desti_5336	1.997e-23	108.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_4315020_3	1121430.JMLG01000022_gene2419	1.909e-25	114.0	COG0247@1|root,COG0247@2|Bacteria,1UZQ0@1239|Firmicutes,24E5H@186801|Clostridia,2672H@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17
LZS2_k127_4322862_0	945713.IALB_2989	9.631e-201	653.0	COG0616@1|root,COG0616@2|Bacteria	2|Bacteria	OU	serine-type peptidase activity	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS2_k127_4322862_10	1125863.JAFN01000001_gene3046	6.644e-28	118.0	2CEMF@1|root,33GFG@2|Bacteria,1NIQ6@1224|Proteobacteria,42X94@68525|delta/epsilon subdivisions,2WSWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4322862_12	1121930.AQXG01000001_gene1165	1.087e-17	98.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Laminin_G_3
LZS2_k127_4322862_14	267377.MMP0501	6.637e-09	69.0	COG3291@1|root,arCOG03396@2157|Archaea	2157|Archaea	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	A2M_comp,CARDB,Prenyltrans,SQHop_cyclase_C,Thiol-ester_cl
LZS2_k127_4322862_9	880073.Calab_2402	5.694e-28	132.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4322862_4	335543.Sfum_0112	6.211e-71	250.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,42SJ9@68525|delta/epsilon subdivisions,2WPBC@28221|Deltaproteobacteria,2MRQE@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS2_k127_4322862_7	1162668.LFE_2449	1.845e-54	196.0	COG2109@1|root,COG2109@2|Bacteria,3J0NJ@40117|Nitrospirae	40117|Nitrospirae	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
LZS2_k127_4322862_13	1385511.N783_18255	1.227e-15	83.0	COG0789@1|root,COG0789@2|Bacteria,1VA1B@1239|Firmicutes,4HKRD@91061|Bacilli,2YAUS@289201|Pontibacillus	91061|Bacilli	K	MerR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
LZS2_k127_4322862_2	589865.DaAHT2_0840	6.929e-108	358.0	COG0694@1|root,COG0822@1|root,COG1251@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,COG1251@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MIAE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
LZS2_k127_4322862_1	1125863.JAFN01000001_gene2667	6.575e-166	529.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS2_k127_4322862_6	237368.SCABRO_01139	1.765e-61	225.0	COG0618@1|root,COG0618@2|Bacteria,2IYQ0@203682|Planctomycetes	203682|Planctomycetes	S	phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
LZS2_k127_4322862_3	330214.NIDE2212	3.235e-87	322.0	COG1075@1|root,COG4995@1|root,COG1075@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NB-ARC,TIR_2,TPR_12
LZS2_k127_4322862_8	1500893.JQNB01000001_gene3300	2.67e-43	165.0	COG0599@1|root,COG0599@2|Bacteria,1N38Z@1224|Proteobacteria,1S5G6@1236|Gammaproteobacteria,1X6C8@135614|Xanthomonadales	135614|Xanthomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS2_k127_4322862_5	426117.M446_2395	5.556e-63	224.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,2TU5B@28211|Alphaproteobacteria,1JS8K@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
LZS2_k127_4322862_11	886293.Sinac_6080	4.812e-25	115.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
LZS2_k127_4322862_15	1499967.BAYZ01000076_gene842	1.433e-06	61.0	COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
LZS2_k127_4322862_16	383372.Rcas_2731	4.474e-05	56.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
LZS2_k127_4352984_0	1379698.RBG1_1C00001G1080	2.837e-152	507.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
LZS2_k127_4352984_2	1123368.AUIS01000001_gene1848	7.041e-24	104.0	28N6F@1|root,2ZBBB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4352984_4	1123228.AUIH01000066_gene3057	4.516e-05	53.0	28N6F@1|root,2ZBBB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4352984_1	1237149.C900_05924	1.301e-48	187.0	COG0823@1|root,COG0823@2|Bacteria,4NIV7@976|Bacteroidetes,47RCS@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS2_k127_4352984_3	1166018.FAES_1627	1.193e-17	85.0	COG0115@1|root,COG0115@2|Bacteria,4PJ29@976|Bacteroidetes,47M6P@768503|Cytophagia	976|Bacteroidetes	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS2_k127_4366835_3	1125863.JAFN01000001_gene3585	3.12e-130	441.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
LZS2_k127_4366835_6	1235792.C808_00891	6.054e-83	292.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,27ISW@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
LZS2_k127_4366835_13	1390370.O203_06185	2.451e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1YDJF@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_4366835_12	1121104.AQXH01000001_gene1064	3.145e-25	115.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1IPXN@117747|Sphingobacteriia	976|Bacteroidetes	S	outer membrane assembly lipoprotein YfiO	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
LZS2_k127_4366835_9	429009.Adeg_0190	9.926e-40	156.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,42EM4@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS2_k127_4366835_0	1499967.BAYZ01000186_gene3985	1.164e-247	793.0	COG0749@1|root,COG0749@2|Bacteria,2NNKA@2323|unclassified Bacteria	2|Bacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS2_k127_4366835_11	1449126.JQKL01000043_gene1891	5.97e-27	118.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,269VN@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
LZS2_k127_4366835_4	986075.CathTA2_0352	2.074e-119	393.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS2_k127_4366835_2	1379698.RBG1_1C00001G0450	3.55e-172	554.0	COG1190@1|root,COG1190@2|Bacteria,2NNMH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.6	ko:K04567,ko:K04568	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03012,ko03016	-	-	iAF1260.b4129,iECDH1ME8569_1439.ECDH1ME8569_3989,iECW_1372.ECW_m4490,iEcDH1_1363.EcDH1_3862,iJN678.lysS,iJO1366.b4129,iWFL_1372.ECW_m4490	DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon
LZS2_k127_4366835_7	96561.Dole_2846	2.532e-73	267.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MHM1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
LZS2_k127_4366835_8	1379698.RBG1_1C00001G0448	1.011e-71	249.0	COG1136@1|root,COG1136@2|Bacteria,2NP7F@2323|unclassified Bacteria	2|Bacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
LZS2_k127_4366835_10	2325.TKV_c20930	1.956e-37	147.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,24JE8@186801|Clostridia,42G0X@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
LZS2_k127_4366835_5	1123242.JH636434_gene3291	1.946e-92	314.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
LZS2_k127_4366835_1	1121468.AUBR01000035_gene1394	4.044e-235	739.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS2_k127_451359_3	272559.BF9343_0472	5.254e-41	156.0	COG0744@1|root,COG0744@2|Bacteria,4NF58@976|Bacteroidetes,2G31J@200643|Bacteroidia,4AM8A@815|Bacteroidaceae	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	pbpF	-	-	-	-	-	-	-	-	-	-	-	Transgly
LZS2_k127_451359_4	880073.Calab_2214	6.727e-05	56.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	-
LZS2_k127_451359_2	1120705.FG95_01036	2.053e-45	182.0	COG1073@1|root,COG1073@2|Bacteria,1R2CS@1224|Proteobacteria,2TZHJ@28211|Alphaproteobacteria,2KBAC@204457|Sphingomonadales	204457|Sphingomonadales	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_451359_0	266117.Rxyl_1165	3.638e-113	376.0	COG2805@1|root,COG2805@2|Bacteria,2I9GT@201174|Actinobacteria,4CPG2@84995|Rubrobacteria	84995|Rubrobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS2_k127_451359_1	7668.SPU_001249-tr	4.483e-58	220.0	COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria	33208|Metazoa	M	ankyrin 3, node of Ranvier (ankyrin G)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
LZS2_k127_4515783_4	378806.STAUR_1623	3.803e-43	162.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS2_k127_4515783_7	1463825.JNXC01000005_gene2397	7.463e-05	45.0	COG0582@1|root,COG0582@2|Bacteria,2IHIW@201174|Actinobacteria,4E2P0@85010|Pseudonocardiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
LZS2_k127_4515783_3	706587.Desti_0293	2.556e-51	185.0	COG1633@1|root,COG1633@2|Bacteria,1N4PW@1224|Proteobacteria,42UZG@68525|delta/epsilon subdivisions,2WNGQ@28221|Deltaproteobacteria,2MS9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS2_k127_4515783_0	1047013.AQSP01000079_gene2040	4.59e-263	848.0	COG0642@1|root,COG3290@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3292@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	-	-	2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3	ko:K07315,ko:K12132,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	FeS,Fe_hyd_lg_C,Fer4,GGDEF,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Reg_prop,Y_Y_Y
LZS2_k127_4515783_6	266117.Rxyl_1946	1.123e-34	144.0	COG0457@1|root,COG0457@2|Bacteria	266117.Rxyl_1946|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4515783_2	269799.Gmet_1654	4.918e-80	275.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,43TKZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	endonuclease III	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
LZS2_k127_4515783_5	398767.Glov_2264	5.164e-40	150.0	COG0011@1|root,COG0011@2|Bacteria,1N1NM@1224|Proteobacteria,42SC4@68525|delta/epsilon subdivisions,2WPHK@28221|Deltaproteobacteria,43VXI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
LZS2_k127_4515783_1	517418.Ctha_0310	5.802e-140	456.0	COG0513@1|root,COG0513@2|Bacteria,1FDMN@1090|Chlorobi	1090|Chlorobi	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
LZS2_k127_4528711_0	529709.PYCH_17610	3.759e-70	243.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,243U2@183968|Thermococci	183968|Thermococci	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_4528711_1	443143.GM18_0949	1.177e-34	148.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,42PNT@68525|delta/epsilon subdivisions,2WM2E@28221|Deltaproteobacteria,43VJ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
LZS2_k127_4528711_2	1000565.METUNv1_03758	4.121e-30	133.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,2KUXN@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_4528711_3	768671.ThimaDRAFT_1941	3.682e-22	111.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
LZS2_k127_4544452_2	1380390.JIAT01000010_gene4107	5.79e-07	59.0	COG4720@1|root,COG4720@2|Bacteria,2HPSE@201174|Actinobacteria,4CR5W@84995|Rubrobacteria	84995|Rubrobacteria	I	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	-
LZS2_k127_4544452_1	880073.Calab_0041	6.766e-10	73.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
LZS2_k127_4544452_0	1379698.RBG1_1C00001G1245	1.739e-26	127.0	COG1629@1|root,COG4771@2|Bacteria,2NRGW@2323|unclassified Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS2_k127_4556157_2	1322246.BN4_10077	1.285e-42	163.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,42SKN@68525|delta/epsilon subdivisions,2WNIQ@28221|Deltaproteobacteria,2MBS5@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS2_k127_4556157_1	96561.Dole_1737	8.037e-43	164.0	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,42S37@68525|delta/epsilon subdivisions,2WNDZ@28221|Deltaproteobacteria,2MJWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS2_k127_4556157_0	933262.AXAM01000091_gene2606	1.294e-119	403.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,42NWR@68525|delta/epsilon subdivisions,2WK2E@28221|Deltaproteobacteria,2MI90@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	DUF3450,MotA_ExbB
LZS2_k127_4556157_3	933262.AXAM01000091_gene2605	3.393e-40	158.0	COG2433@1|root,COG2433@2|Bacteria,1QWQ9@1224|Proteobacteria,42WRY@68525|delta/epsilon subdivisions,2WQU6@28221|Deltaproteobacteria,2MPKU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
LZS2_k127_4556157_4	1191523.MROS_2643	2.095e-22	101.0	COG1520@1|root,COG5492@1|root,COG1520@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,TIG
LZS2_k127_4577867_5	880073.Calab_2402	6.628e-44	184.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4577867_6	234267.Acid_1921	1.933e-38	160.0	COG3852@1|root,COG3852@2|Bacteria,3Y9A1@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS2_k127_4577867_2	398767.Glov_3076	2.215e-116	390.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43TS4@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS2_k127_4577867_3	760568.Desku_1231	3.751e-91	310.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
LZS2_k127_4577867_4	56780.SYN_02636	4.039e-71	250.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
LZS2_k127_4577867_0	1122134.KB893650_gene584	2.142e-211	675.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1XP2X@135619|Oceanospirillales	135619|Oceanospirillales	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
LZS2_k127_4577867_1	246194.CHY_1350	4.754e-128	420.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin
LZS2_k127_4577867_8	880073.Calab_0921	1.612e-18	101.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS2_k127_4577867_7	926564.KI911762_gene5116	7.464e-33	148.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4F3NQ@85017|Promicromonosporaceae	201174|Actinobacteria	M	PFAM peptidase M6 immune inhibitor A	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
LZS2_k127_4581897_14	1158182.KB905022_gene1194	1.627e-48	179.0	COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,1S2T5@1236|Gammaproteobacteria,1WYYI@135613|Chromatiales	135613|Chromatiales	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_4581897_4	1027273.GZ77_10335	2.654e-81	276.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XJCI@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
LZS2_k127_4581897_8	1278073.MYSTI_08089	1.905e-68	249.0	COG1680@1|root,COG1729@1|root,COG1680@2|Bacteria,COG1729@2|Bacteria,1R49D@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
LZS2_k127_4581897_19	1121930.AQXG01000001_gene1216	2.223e-21	111.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Beta_helix,F5_F8_type_C
LZS2_k127_4581897_6	247490.KSU1_C0449	2.485e-77	290.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS2_k127_4581897_23	1047013.AQSP01000120_gene963	0.000119	49.0	2AB38@1|root,310H2@2|Bacteria,2NRWF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4581897_16	1499967.BAYZ01000136_gene21	8.794e-43	165.0	2E115@1|root,32WH3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4581897_3	317025.Tcr_1011	3.983e-93	316.0	COG3391@1|root,COG3391@2|Bacteria,1RGAJ@1224|Proteobacteria,1S2QK@1236|Gammaproteobacteria,462Y7@72273|Thiotrichales	72273|Thiotrichales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
LZS2_k127_4581897_15	1121396.KB893066_gene1589	4.962e-47	173.0	COG0589@1|root,COG0589@2|Bacteria,1PEB7@1224|Proteobacteria,42XVC@68525|delta/epsilon subdivisions,2WSNF@28221|Deltaproteobacteria,2MMDT@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS2_k127_4581897_1	1121396.KB893066_gene1590	8.368e-203	642.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,42PNI@68525|delta/epsilon subdivisions,2WJNF@28221|Deltaproteobacteria,2MQ1R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
LZS2_k127_4581897_20	697282.Mettu_3918	1.537e-14	78.0	COG4420@1|root,COG4420@2|Bacteria,1PU06@1224|Proteobacteria,1TBTS@1236|Gammaproteobacteria,1XGWA@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
LZS2_k127_4581897_2	96561.Dole_0974	7.546e-96	323.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WPDW@28221|Deltaproteobacteria,2MJNH@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
LZS2_k127_4581897_7	861299.J421_1965	1.079e-71	249.0	COG2020@1|root,COG2020@2|Bacteria,1ZU79@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
LZS2_k127_4581897_18	1201293.AKXQ01000009_gene939	3.823e-29	120.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,1RSIB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_4581897_10	349521.HCH_04843	8.16e-62	215.0	COG0454@1|root,COG0456@2|Bacteria,1RI35@1224|Proteobacteria,1S66W@1236|Gammaproteobacteria,1XPIN@135619|Oceanospirillales	135619|Oceanospirillales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
LZS2_k127_4581897_11	211586.SO_1373	3.149e-53	189.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,2QBWQ@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
LZS2_k127_4581897_0	1304885.AUEY01000017_gene3720	2.318e-289	893.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,42MIN@68525|delta/epsilon subdivisions,2WJC5@28221|Deltaproteobacteria,2MJCT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalase	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
LZS2_k127_4581897_12	1121403.AUCV01000037_gene4264	5.293e-53	190.0	COG0735@1|root,COG0735@2|Bacteria,1Q2NI@1224|Proteobacteria,42SV3@68525|delta/epsilon subdivisions,2WPH8@28221|Deltaproteobacteria,2MKA3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS2_k127_4581897_9	945713.IALB_0041	3.075e-67	239.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	mhpC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
LZS2_k127_4581897_17	290315.Clim_1053	3.092e-41	159.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	chpE	-	-	ko:K06600,ko:K06895	-	-	-	-	ko00000,ko02000,ko02035	2.A.75.1,2.A.76	-	-	LysE
LZS2_k127_4581897_13	1121920.AUAU01000017_gene1231	9.793e-53	188.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	Z012_09115	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
LZS2_k127_4581897_5	1121396.KB893062_gene2737	6.635e-81	279.0	COG2014@1|root,COG2014@2|Bacteria,1NFAE@1224|Proteobacteria,42NC4@68525|delta/epsilon subdivisions,2WKS2@28221|Deltaproteobacteria,2MJJ4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364
LZS2_k127_4581897_22	1294265.JCM21738_2407	5.043e-09	67.0	COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,4HCYJ@91061|Bacilli,1ZAPI@1386|Bacillus	91061|Bacilli	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_4581897_21	7739.XP_002601707.1	2.888e-10	72.0	KOG2177@1|root,KOG2177@2759|Eukaryota,38EA3@33154|Opisthokonta,3BFJH@33208|Metazoa,3CRTV@33213|Bilateria,47YXB@7711|Chordata	33208|Metazoa	O	zinc ion binding	-	-	2.3.2.27	ko:K11997,ko:K12026,ko:K12035	ko05206,map05206	-	-	-	ko00000,ko00001,ko01000,ko03019,ko04121	-	-	-	NHL,zf-B_box,zf-C3HC4,zf-RING_UBOX
LZS2_k127_460326_1	1379698.RBG1_1C00001G1514	1.404e-66	239.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
LZS2_k127_460326_2	269799.Gmet_0890	2.746e-55	208.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,43U42@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
LZS2_k127_460326_0	795359.TOPB45_0431	4.064e-101	340.0	COG0536@1|root,COG0536@2|Bacteria,2GHPW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
LZS2_k127_4646922_2	1161401.ASJA01000006_gene1887	9.722e-61	219.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,2VF2W@28211|Alphaproteobacteria,43WSP@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
LZS2_k127_4646922_0	1125863.JAFN01000001_gene912	0.0	1040.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS2_k127_4646922_1	1379698.RBG1_1C00001G0607	1.162e-99	337.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS2_k127_4690425_0	886293.Sinac_5461	7.485e-100	339.0	COG0438@1|root,COG0438@2|Bacteria,2J10U@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_4690425_4	1232410.KI421418_gene2352	5.831e-15	85.0	COG3584@1|root,COG3584@2|Bacteria,1NMA8@1224|Proteobacteria,42XYE@68525|delta/epsilon subdivisions,2WTAA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4690425_3	314230.DSM3645_14155	9.153e-39	151.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
LZS2_k127_4690425_1	1125863.JAFN01000001_gene207	7.575e-98	326.0	COG1028@1|root,COG1028@2|Bacteria,1QXA0@1224|Proteobacteria,42UQH@68525|delta/epsilon subdivisions,2WQ5R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS2_k127_4690425_2	1394178.AWOO02000084_gene1152	1.536e-88	303.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4EH93@85012|Streptosporangiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS2_k127_4724897_1	638303.Thal_0079	1.997e-82	281.0	COG1206@1|root,COG1206@2|Bacteria,2G3NY@200783|Aquificae	200783|Aquificae	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
LZS2_k127_4724897_0	880073.Calab_0884	7.588e-248	785.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
LZS2_k127_4724897_3	1485544.JQKP01000002_gene1571	1.877e-05	54.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,44VVY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF494)	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
LZS2_k127_4724897_2	518766.Rmar_0369	3.621e-23	103.0	COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,1FIX0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
LZS2_k127_4726256_2	204669.Acid345_3562	3.375e-34	141.0	COG1044@1|root,COG1044@2|Bacteria,3Y2ZS@57723|Acidobacteria,2JIC3@204432|Acidobacteriia	204432|Acidobacteriia	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
LZS2_k127_4726256_0	309799.DICTH_1798	3.29e-87	297.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_4726256_1	1379698.RBG1_1C00001G1260	1.365e-49	197.0	2DRGI@1|root,33BMN@2|Bacteria	2|Bacteria	S	PilX N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
LZS2_k127_4726256_4	261292.Nit79A3_0225	1.236e-05	54.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,372B4@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
LZS2_k127_4726256_3	515635.Dtur_1182	2.325e-28	125.0	COG3156@1|root,COG3156@2|Bacteria	2|Bacteria	U	protein secretion	VP0659	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	DUF4900
LZS2_k127_4726268_1	945713.IALB_0695	5.036e-102	371.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS2_k127_4726268_0	1047013.AQSP01000079_gene2041	1.7e-188	626.0	COG0841@1|root,COG0841@2|Bacteria,2NQI6@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	mdtC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_4726268_2	1047013.AQSP01000079_gene2044	2.351e-39	155.0	COG0845@1|root,COG0845@2|Bacteria,2NR3D@2323|unclassified Bacteria	2|Bacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS2_k127_4767333_4	1120973.AQXL01000134_gene1579	2.623e-32	138.0	COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli,2794E@186823|Alicyclobacillaceae	91061|Bacilli	L	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
LZS2_k127_4767333_2	1379698.RBG1_1C00001G1782	5.789e-46	186.0	COG4775@1|root,COG4775@2|Bacteria,2NPNI@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS2_k127_4767333_1	945713.IALB_1764	4.483e-82	308.0	COG5448@1|root,COG5448@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
LZS2_k127_4767333_5	45351.EDO47729	8.242e-24	113.0	KOG2177@1|root,KOG2177@2759|Eukaryota,38EA3@33154|Opisthokonta,3BFJH@33208|Metazoa	33208|Metazoa	O	zinc ion binding	-	-	-	ko:K11997	-	-	-	-	ko00000,ko04121	-	-	-	Filamin,NHL,zf-B_box
LZS2_k127_4767333_6	945713.IALB_1059	1.327e-16	89.0	2EAWV@1|root,334Y2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4767333_7	1191523.MROS_1892	8.486e-10	70.0	2CUTJ@1|root,32SW3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4767333_3	459349.CLOAM1225	6.251e-43	170.0	COG2067@1|root,COG2067@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4767333_0	1379698.RBG1_1C00001G1789	1.642e-100	367.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
LZS2_k127_4773757_0	1232410.KI421413_gene543	1.248e-181	582.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,43T3U@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS2_k127_4773757_2	1117108.PAALTS15_08139	1.027e-41	163.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,274IB@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_4773757_4	574087.Acear_0300	8.504e-34	148.0	COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,24DMW@186801|Clostridia	186801|Clostridia	S	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
LZS2_k127_4773757_3	1120965.AUBV01000007_gene2669	7.415e-41	159.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47K51@768503|Cytophagia	976|Bacteroidetes	S	PFAM GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
LZS2_k127_4773757_1	945713.IALB_2711	3.997e-113	376.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_4773757_5	1379270.AUXF01000005_gene601	3.293e-19	92.0	2E5IJ@1|root,3309Y@2|Bacteria,1ZTU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4807838_4	1121104.AQXH01000001_gene1638	1.883e-14	84.0	2E10Y@1|root,32WGY@2|Bacteria,4NTDG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4807838_3	485913.Krac_8040	4.388e-41	168.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DA1-like,GAF,Guanylate_cyc,HAMP,PAS_4,PAS_9,Response_reg,dCache_1
LZS2_k127_4807838_0	1047013.AQSP01000079_gene2039	2.551e-151	490.0	2C57D@1|root,2Z7RS@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
LZS2_k127_4807838_2	929556.Solca_0196	2.951e-68	259.0	COG1075@1|root,COG1075@2|Bacteria,4NJMQ@976|Bacteroidetes,1IYWC@117747|Sphingobacteriia	976|Bacteroidetes	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF676,PGAP1
LZS2_k127_4807838_5	1191523.MROS_0962	2.172e-14	87.0	COG2911@1|root,COG3867@1|root,COG2911@2|Bacteria,COG3867@2|Bacteria	2|Bacteria	G	arabinogalactan endo-1,4-beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,F5_F8_type_C,FlgD_ig,Glyco_hydro_53,He_PIG,Peptidase_S74,RicinB_lectin_2,SLH,fn3
LZS2_k127_4807838_6	755732.Fluta_0658	3.239e-11	74.0	COG3137@1|root,COG3137@2|Bacteria,4NJH6@976|Bacteroidetes,1IEQS@117743|Flavobacteriia,2PB3G@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
LZS2_k127_4807838_1	1379698.RBG1_1C00001G0518	6.836e-91	312.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS2_k127_4821874_1	243231.GSU1703	2.995e-95	318.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,43TVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS2_k127_4821874_3	429009.Adeg_0382	1.369e-28	121.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,42J0Y@68295|Thermoanaerobacterales	186801|Clostridia	S	flavin reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
LZS2_k127_4821874_0	1379698.RBG1_1C00001G1080	2.027e-219	704.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
LZS2_k127_4821874_2	6669.EFX78291	1.932e-37	160.0	COG4870@1|root,KOG1543@2759|Eukaryota	2759|Eukaryota	O	cysteine-type peptidase activity	-	GO:0000003,GO:0000323,GO:0000746,GO:0000747,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009057,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0019953,GO:0022414,GO:0030163,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044703,GO:0044764,GO:0051603,GO:0051704,GO:0070011,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.14.1,3.4.22.1,3.4.22.15,3.4.22.27,3.4.22.38	ko:K01275,ko:K01363,ko:K01365,ko:K01368,ko:K01371	ko04140,ko04142,ko04145,ko04210,ko04380,ko04612,ko04620,ko04621,ko04924,ko05152,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04380,map04612,map04620,map04621,map04924,map05152,map05205,map05323,map05418	-	-	-	ko00000,ko00001,ko00536,ko00537,ko01000,ko01002,ko03110,ko04147	-	-	-	Inhibitor_I29,Peptidase_C1
LZS2_k127_4831536_5	1297742.A176_07059	2.008e-35	141.0	COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4831536_0	1123371.ATXH01000009_gene1104	2.017e-132	438.0	COG1109@1|root,COG1109@2|Bacteria,2GHQ7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS2_k127_4831536_6	421531.IX38_13350	8.417e-14	78.0	COG0071@1|root,COG0071@2|Bacteria,4NQXY@976|Bacteroidetes,1I382@117743|Flavobacteriia,3ZRSA@59732|Chryseobacterium	976|Bacteroidetes	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS2_k127_4831536_3	1379698.RBG1_1C00001G1815	5.242e-68	249.0	COG0477@1|root,COG2814@2|Bacteria,2NPJ1@2323|unclassified Bacteria	2|Bacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_4831536_1	485913.Krac_11908	4.528e-90	308.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS2_k127_4831536_4	1219626.HMPREF1639_08340	2.072e-41	165.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,25QXD@186804|Peptostreptococcaceae	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
LZS2_k127_4831536_2	545697.HMPREF0216_02608	2.086e-73	262.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
LZS2_k127_4831536_7	1336249.JADW01000029_gene2831	6.253e-11	67.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2U6ZQ@28211|Alphaproteobacteria,4B7PV@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
LZS2_k127_4876605_3	406818.XBJ1_4402	4.8e-08	55.0	COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,1RNFH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
LZS2_k127_4876605_0	1379698.RBG1_1C00001G0910	1.521e-42	165.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_4876605_1	706587.Desti_1103	1.3e-19	94.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria,2MQKK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Molybdopterin guanine dinucleotide synthesis protein B	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
LZS2_k127_4876605_2	290397.Adeh_3987	2.22e-10	62.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS2_k127_4880371_3	1379698.RBG1_1C00001G1740	3.389e-75	273.0	COG3852@1|root,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PAS_9
LZS2_k127_4880371_2	671143.DAMO_3011	4.171e-132	432.0	COG1459@1|root,COG1459@2|Bacteria,2NP2J@2323|unclassified Bacteria	2|Bacteria	U	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
LZS2_k127_4880371_1	379066.GAU_2569	5.176e-148	476.0	COG2805@1|root,COG2805@2|Bacteria,1ZSQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS2_k127_4880371_0	639282.DEFDS_1109	1.986e-197	629.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
LZS2_k127_4880371_5	795955.AFRW01000041_gene69	2.301e-08	61.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,1WBVX@1268|Micrococcaceae	201174|Actinobacteria	L	SLBB domain	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
LZS2_k127_4880371_4	398767.Glov_3556	6.988e-60	230.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43BRF@68525|delta/epsilon subdivisions,2WKAH@28221|Deltaproteobacteria,43TV7@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
LZS2_k127_4880371_6	926559.JoomaDRAFT_3006	0.0004779	51.0	COG1629@1|root,COG4771@2|Bacteria,4PKFM@976|Bacteroidetes,1IJQT@117743|Flavobacteriia	976|Bacteroidetes	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
LZS2_k127_4897120_1	1232410.KI421412_gene411	5.353e-70	246.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS2_k127_4897120_0	273526.SMDB11_4282	4.51e-76	266.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,401RA@613|Serratia	1236|Gammaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849	Porphobil_deam,Porphobil_deamC
LZS2_k127_4897120_3	888060.HMPREF9081_1575	1.999e-39	156.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,4H32B@909932|Negativicutes	909932|Negativicutes	H	Belongs to the precorrin methyltransferase family	cobA	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
LZS2_k127_4897120_2	1167006.UWK_03430	1.66e-43	162.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,2MI2X@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
LZS2_k127_4900382_2	1449976.KALB_7283	0.0007856	50.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria,4E1H2@85010|Pseudonocardiales	201174|Actinobacteria	S	Immune inhibitor A peptidase M6	ina	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
LZS2_k127_4900382_1	518766.Rmar_1484	1.994e-17	96.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Kelch_4
LZS2_k127_4900382_0	471854.Dfer_3148	3.157e-41	169.0	COG2931@1|root,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
LZS2_k127_4911843_0	485916.Dtox_1820	4.495e-211	662.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,2644N@186807|Peptococcaceae	186801|Clostridia	L	Group II intron, maturase-specific domain	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
LZS2_k127_4911843_1	1343739.PAP_00225	6.951e-81	280.0	COG0697@1|root,arCOG00271@2157|Archaea,2XXKE@28890|Euryarchaeota,2434U@183968|Thermococci	183968|Thermococci	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_4911843_3	1047013.AQSP01000114_gene698	3.067e-67	239.0	2CK1R@1|root,31E53@2|Bacteria,2NR8M@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4911843_2	1047013.AQSP01000114_gene697	1.118e-76	263.0	COG2006@1|root,COG2006@2|Bacteria,2NQF7@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_4929060_3	926569.ANT_15460	3.654e-82	280.0	COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi	200795|Chloroflexi	J	SMART PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
LZS2_k127_4929060_1	1125863.JAFN01000001_gene586	1.344e-96	336.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
LZS2_k127_4929060_5	926690.KE386573_gene2094	1.662e-56	211.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,23STJ@183963|Halobacteria	183963|Halobacteria	I	COG0183 Acetyl-CoA acetyltransferase	acaB1	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_4929060_6	65093.PCC7418_2598	9.237e-30	124.0	COG1963@1|root,COG1963@2|Bacteria,1G5PI@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
LZS2_k127_4929060_4	1142394.PSMK_30020	3.521e-61	226.0	COG1192@1|root,COG3170@1|root,COG1192@2|Bacteria,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496,ko:K09000	-	-	-	-	ko00000,ko02048,ko03036,ko04812	-	-	-	AAA_31
LZS2_k127_4929060_7	1089550.ATTH01000001_gene1005	3.088e-11	76.0	COG1404@1|root,COG3591@1|root,COG4932@1|root,COG1404@2|Bacteria,COG3591@2|Bacteria,COG4932@2|Bacteria,4NG2K@976|Bacteroidetes,1FJTD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EO	Trypsin-like serine protease	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	P_proprotein,Trypsin_2
LZS2_k127_4929060_0	161156.JQKW01000010_gene345	4.032e-306	961.0	COG0542@1|root,COG0542@2|Bacteria,2GGRY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS2_k127_4929060_2	997884.HMPREF1068_00362	1.168e-87	327.0	COG1361@1|root,COG1520@1|root,COG4870@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia,4ATRZ@815|Bacteroidaceae	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
LZS2_k127_495438_4	697281.Mahau_2374	4.996e-45	175.0	COG2199@1|root,COG3706@2|Bacteria,1VADD@1239|Firmicutes,25E7Q@186801|Clostridia,42J5P@68295|Thermoanaerobacterales	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_9,Response_reg,TPR_8
LZS2_k127_495438_1	404589.Anae109_2774	1.1e-121	399.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_495438_5	768710.DesyoDRAFT_1032	6.061e-34	138.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,2630J@186807|Peptococcaceae	186801|Clostridia	S	PFAM BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
LZS2_k127_495438_2	502025.Hoch_3436	1.129e-91	321.0	COG1196@1|root,COG1196@2|Bacteria,1R3XQ@1224|Proteobacteria,42YF5@68525|delta/epsilon subdivisions,2WUDV@28221|Deltaproteobacteria,2YUE5@29|Myxococcales	28221|Deltaproteobacteria	D	HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid
LZS2_k127_495438_0	760568.Desku_1514	9.127e-170	543.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,26072@186807|Peptococcaceae	186801|Clostridia	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_495438_3	880072.Desac_0398	2.44e-79	268.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,2MQY0@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
LZS2_k127_4963552_2	1499967.BAYZ01000161_gene372	9.301e-44	167.0	COG0572@1|root,COG0572@2|Bacteria,2NRHW@2323|unclassified Bacteria	2|Bacteria	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_18,AAA_33,Hydrolase_like,NTP_transferase,PRK,RNA_lig_T4_1
LZS2_k127_4963552_0	1047013.AQSP01000130_gene1859	2.857e-118	392.0	COG0438@1|root,COG0438@2|Bacteria,2NQFS@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	sps	GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576	2.4.1.14,2.4.1.246	ko:K00696,ko:K13058	ko00500,ko01100,map00500,map01100	-	R00766,R08947	RC00005,RC00028,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,S6PP,Sucrose_synth
LZS2_k127_4963552_1	1247726.MIM_c12560	9.328e-59	211.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,3T1CP@506|Alcaligenaceae	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
LZS2_k127_4963552_3	290397.Adeh_0693	5.367e-06	48.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,2YU7A@29|Myxococcales	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS2_k127_4988898_2	289376.THEYE_A2006	2.553e-10	71.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,3J18S@40117|Nitrospirae	40117|Nitrospirae	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_4988898_1	485913.Krac_1060	8.078e-26	112.0	COG0789@1|root,COG0789@2|Bacteria,2G9AM@200795|Chloroflexi	200795|Chloroflexi	K	Transcription regulator MerR DNA binding	-	-	-	ko:K13638	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
LZS2_k127_4988898_0	316067.Geob_0176	1.255e-141	473.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y50@68525|delta/epsilon subdivisions,2WUBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HTH_8,PAS_4,Sigma54_activat
LZS2_k127_5052305_1	880073.Calab_0853	2.692e-82	284.0	COG2262@1|root,COG2262@2|Bacteria,2NNWI@2323|unclassified Bacteria	2|Bacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS2_k127_5052305_2	1146883.BLASA_1863	3.387e-34	147.0	COG0477@1|root,COG2814@2|Bacteria,2I7QC@201174|Actinobacteria,4EXI7@85013|Frankiales	2|Bacteria	EGP	Evidence 2b Function of strongly homologous gene	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3,Thymidylate_kin
LZS2_k127_5052305_0	880073.Calab_2508	4.541e-108	360.0	COG2866@1|root,COG2866@2|Bacteria,2NQNH@2323|unclassified Bacteria	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
LZS2_k127_5054150_1	398767.Glov_2832	4.509e-58	205.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
LZS2_k127_5054150_3	1232410.KI421428_gene1047	1.742e-17	90.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria,43V6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
LZS2_k127_5054150_0	1379698.RBG1_1C00001G0723	4.647e-64	243.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
LZS2_k127_5054150_2	264732.Moth_0275	4.382e-51	185.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
LZS2_k127_5054852_7	309799.DICTH_1700	3.142e-35	153.0	COG1293@1|root,COG1293@2|Bacteria	2|Bacteria	K	actin binding	FbpA	-	-	ko:K12341	ko03070,map03070	-	-	-	ko00000,ko00001,ko02044	1.B.40.1.1	-	-	DUF814,FbpA
LZS2_k127_5054852_5	273068.TTE1513	1.079e-58	215.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,42EU9@68295|Thermoanaerobacterales	186801|Clostridia	S	domain protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
LZS2_k127_5054852_6	401526.TcarDRAFT_2086	2.238e-55	201.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4H3ZW@909932|Negativicutes	909932|Negativicutes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
LZS2_k127_5054852_1	717605.Theco_2187	5.232e-107	359.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
LZS2_k127_5054852_4	880073.Calab_0007	2.606e-63	226.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS2_k127_5054852_0	1499967.BAYZ01000088_gene5101	9.22e-141	461.0	COG0305@1|root,COG0305@2|Bacteria,2NNKG@2323|unclassified Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
LZS2_k127_5054852_3	1379698.RBG1_1C00001G0978	2.226e-72	254.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
LZS2_k127_5054852_2	1379698.RBG1_1C00001G0979	8.448e-92	310.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
LZS2_k127_5054852_8	1223410.KN050846_gene517	5.132e-13	78.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1HXN5@117743|Flavobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
LZS2_k127_5069958_1	76114.ebA2787	3.64e-32	129.0	2C9YI@1|root,337RN@2|Bacteria,1NBDR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5069958_3	436308.Nmar_1299	0.000285	48.0	COG0642@1|root,COG0840@1|root,arCOG02344@2157|Archaea,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	2.7.13.3	ko:K03406,ko:K07709	ko02020,ko02030,map02020,map02030	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,MCPsignal,dCache_1
LZS2_k127_5069958_2	76114.ebA2787	2.018e-24	108.0	2C9YI@1|root,337RN@2|Bacteria,1NBDR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5069958_0	485915.Dret_1750	1.933e-80	273.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
LZS2_k127_5122964_9	518766.Rmar_1808	2.066e-23	105.0	COG2890@1|root,COG2890@2|Bacteria,4NDZB@976|Bacteroidetes,1FJ98@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25
LZS2_k127_5122964_2	706587.Desti_4010	1.271e-123	405.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2MQ5C@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS2_k127_5122964_3	316067.Geob_0684	3.872e-79	276.0	COG3872@1|root,COG3872@2|Bacteria,1RCB0@1224|Proteobacteria,42R3I@68525|delta/epsilon subdivisions,2WMZR@28221|Deltaproteobacteria,43U2U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
LZS2_k127_5122964_8	744872.Spica_1603	1.46e-29	119.0	COG0254@1|root,COG0254@2|Bacteria,2J93Z@203691|Spirochaetes	203691|Spirochaetes	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
LZS2_k127_5122964_0	880073.Calab_1925	3.081e-204	641.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
LZS2_k127_5122964_11	5911.EAS01029	4.041e-11	74.0	COG0457@1|root,COG0639@1|root,COG3914@1|root,KOG0376@2759|Eukaryota,KOG1126@2759|Eukaryota,KOG4626@2759|Eukaryota,3ZDCY@5878|Ciliophora	5878|Ciliophora	GOT	TPR Domain containing protein	-	-	-	ko:K12600	ko03018,map03018	M00392	-	-	ko00000,ko00001,ko00002,ko03019	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS2_k127_5122964_1	1232410.KI421421_gene3895	2.16e-144	486.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,43RXS@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
LZS2_k127_5122964_7	635013.TherJR_2129	6.41e-38	147.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_5122964_4	243231.GSU1939	4.131e-74	283.0	COG0642@1|root,COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2206@2|Bacteria,1NSAV@1224|Proteobacteria,42Z68@68525|delta/epsilon subdivisions,2WURV@28221|Deltaproteobacteria,43U68@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD_5,HisKA
LZS2_k127_5122964_6	944479.JQLX01000013_gene1442	1.025e-44	188.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,HD_5
LZS2_k127_5122964_5	1121430.JMLG01000003_gene597	5.175e-47	195.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS2_k127_5122964_10	358681.BBR47_49450	6.643e-17	82.0	COG5000@1|root,COG5000@2|Bacteria,1V3DV@1239|Firmicutes,4HGCX@91061|Bacilli,274DD@186822|Paenibacillaceae	91061|Bacilli	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS2_k127_5125985_2	1232437.KL661958_gene2886	3.214e-119	387.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
LZS2_k127_5125985_5	706587.Desti_1916	1.623e-88	297.0	COG1414@1|root,COG1908@1|root,COG1414@2|Bacteria,COG1908@2|Bacteria,1RBWB@1224|Proteobacteria,42QRJ@68525|delta/epsilon subdivisions,2WN64@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	bamF	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2083	FlpD,HTH_5
LZS2_k127_5125985_7	706587.Desti_1917	5.392e-68	235.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,43B7N@68525|delta/epsilon subdivisions,2X6M3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
LZS2_k127_5125985_0	56780.SYN_01648	0.0	1029.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding	bamH	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_2080	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
LZS2_k127_5125985_4	1232437.KL661958_gene2890	2.126e-92	310.0	COG1034@1|root,COG1034@2|Bacteria,1RK80@1224|Proteobacteria,43CTD@68525|delta/epsilon subdivisions,2X80Y@28221|Deltaproteobacteria,2MPQ2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_7
LZS2_k127_5125985_3	1232437.KL661958_gene2891	2.96e-109	359.0	COG1526@1|root,COG1526@2|Bacteria,1NRU0@1224|Proteobacteria,42PRH@68525|delta/epsilon subdivisions,2WPXH@28221|Deltaproteobacteria,2MJR0@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ,MobB
LZS2_k127_5125985_1	76114.ebA5622	1.373e-247	792.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,2KVC6@206389|Rhodocyclales	206389|Rhodocyclales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS2_k127_5125985_6	768706.Desor_2602	2.712e-75	258.0	COG0437@1|root,COG0437@2|Bacteria,1V5RH@1239|Firmicutes,24IFS@186801|Clostridia,261VT@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S binding domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
LZS2_k127_5125985_9	1123376.AUIU01000012_gene1472	4.515e-22	108.0	COG3301@1|root,COG3301@2|Bacteria	2|Bacteria	P	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD,NrfD_2
LZS2_k127_5125985_8	929712.KI912613_gene182	5.457e-30	127.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CQ2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
LZS2_k127_5162676_0	1379698.RBG1_1C00001G1659	4.193e-101	351.0	COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
LZS2_k127_5162676_5	697281.Mahau_0162	5.242e-29	120.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,42GPV@68295|Thermoanaerobacterales	186801|Clostridia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
LZS2_k127_5162676_2	203119.Cthe_2142	4.774e-65	228.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3WHNZ@541000|Ruminococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
LZS2_k127_5162676_4	861299.J421_2885	9.025e-39	151.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
LZS2_k127_5162676_1	269799.Gmet_3417	4.562e-86	288.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43T5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
LZS2_k127_5162676_6	290512.Paes_1687	2.571e-24	108.0	COG1267@1|root,COG1267@2|Bacteria,1FE6P@1090|Chlorobi	1090|Chlorobi	I	PFAM phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
LZS2_k127_5162676_3	1089553.Tph_c11560	1.862e-56	212.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,42F5V@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
LZS2_k127_519100_0	555079.Toce_1696	3.908e-222	734.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,42FMD@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM glycosidase related protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
LZS2_k127_519100_1	1191523.MROS_0944	2.195e-74	264.0	COG3579@1|root,COG3579@2|Bacteria	2|Bacteria	E	homocysteine catabolic process	-	-	3.4.22.40	ko:K01372	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C1,Peptidase_C1_2
LZS2_k127_519100_2	485915.Dret_0882	4.165e-05	46.0	2DD8W@1|root,2ZH3F@2|Bacteria,1PBGJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_53115_2	525904.Tter_0496	4.289e-08	63.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
LZS2_k127_53115_1	379066.GAU_1710	2.778e-72	255.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
LZS2_k127_53115_0	1121468.AUBR01000034_gene1358	1.502e-128	417.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,42FIA@68295|Thermoanaerobacterales	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS2_k127_5372785_2	880073.Calab_1665	1.457e-53	199.0	COG0697@1|root,COG0697@2|Bacteria,2NPZZ@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
LZS2_k127_5372785_1	324602.Caur_2936	1.525e-74	258.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
LZS2_k127_5372785_8	1123274.KB899414_gene3754	1.004e-06	61.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
LZS2_k127_5372785_7	1379698.RBG1_1C00001G1334	3.927e-09	68.0	COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria	2|Bacteria	I	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
LZS2_k127_5372785_5	679201.HMPREF9334_00679	1.361e-18	98.0	COG3307@1|root,COG3307@2|Bacteria,1V4DY@1239|Firmicutes,4H4E3@909932|Negativicutes	909932|Negativicutes	M	O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS2_k127_5372785_0	880073.Calab_1598	0.0	1230.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
LZS2_k127_5372785_3	886293.Sinac_2689	3.191e-25	122.0	COG3119@1|root,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
LZS2_k127_5372785_4	344747.PM8797T_13108	4.153e-22	110.0	COG1807@1|root,COG1807@2|Bacteria,2IZNI@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
LZS2_k127_5372785_6	1120972.AUMH01000002_gene2681	1.692e-13	72.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,4HBER@91061|Bacilli,2782J@186823|Alicyclobacillaceae	91061|Bacilli	E	B12 binding domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS2_k127_5414800_9	641491.DND132_1735	6.911e-12	67.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,2M883@213115|Desulfovibrionales	28221|Deltaproteobacteria	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
LZS2_k127_5414800_8	1321781.HMPREF1985_01504	7.504e-23	104.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,4H581@909932|Negativicutes	909932|Negativicutes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
LZS2_k127_5414800_1	517418.Ctha_0344	3.554e-198	628.0	COG3259@1|root,COG3259@2|Bacteria,1FDQF@1090|Chlorobi	1090|Chlorobi	C	PFAM nickel-dependent hydrogenase, large subunit	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
LZS2_k127_5414800_5	517418.Ctha_0345	1.756e-104	348.0	COG1941@1|root,COG1941@2|Bacteria,1FDE2@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
LZS2_k127_5414800_3	517418.Ctha_0346	5.944e-162	516.0	COG0543@1|root,COG0543@2|Bacteria,1FDP4@1090|Chlorobi	1090|Chlorobi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
LZS2_k127_5414800_2	517418.Ctha_0347	6.118e-170	539.0	COG1150@1|root,COG1150@2|Bacteria,1FDMP@1090|Chlorobi	1090|Chlorobi	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
LZS2_k127_5414800_6	521011.Mpal_1345	9.177e-77	269.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
LZS2_k127_5414800_7	1047013.AQSP01000130_gene1867	2.977e-25	107.0	2FDJV@1|root,345M5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5414800_0	518766.Rmar_0638	2.475e-281	870.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1FIMH@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS2_k127_5414800_4	1313421.JHBV01000003_gene663	1.103e-149	486.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQP1@117747|Sphingobacteriia	976|Bacteroidetes	G	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
LZS2_k127_5464813_0	909663.KI867150_gene885	1.822e-199	632.0	COG0574@1|root,COG1669@1|root,COG0574@2|Bacteria,COG1669@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2MR7X@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,PPDK_N
LZS2_k127_5464813_1	1499967.BAYZ01000119_gene3214	7.385e-97	325.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
LZS2_k127_5464813_4	1121918.ARWE01000001_gene2026	5.569e-28	122.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions,2WP03@28221|Deltaproteobacteria,43SHH@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
LZS2_k127_5464813_6	1047013.AQSP01000132_gene1742	1.282e-14	87.0	COG3391@1|root,COG3391@2|Bacteria,2NQ4G@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,TolB_like
LZS2_k127_5464813_3	243365.CV_2724	1.062e-37	150.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VJQ5@28216|Betaproteobacteria,2KPH4@206351|Neisseriales	206351|Neisseriales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS2_k127_5464813_2	686340.Metal_2727	6.827e-82	292.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMP5@1236|Gammaproteobacteria,1XER7@135618|Methylococcales	135618|Methylococcales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS2_k127_5464813_5	1411685.U062_01738	1.333e-17	93.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,1RPEQ@1236|Gammaproteobacteria,1J4P2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
LZS2_k127_5477208_4	633697.EubceDRAFT1_1508	5.29e-15	82.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,25VB2@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
LZS2_k127_5477208_2	1444309.JAQG01000110_gene1767	5.06e-31	124.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,26Y5D@186822|Paenibacillaceae	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS2_k127_5477208_0	1121438.JNJA01000017_gene1409	4.893e-239	749.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2M84Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS2_k127_5477208_1	1123371.ATXH01000022_gene959	3.346e-93	319.0	COG0436@1|root,COG0436@2|Bacteria,2GGY5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_5477208_3	927704.SELR_27260	1.395e-20	95.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4H54R@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
LZS2_k127_5477208_5	1179226.AJXO01000033_gene1147	5.674e-15	78.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,4GYZA@90964|Staphylococcaceae	91061|Bacilli	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
LZS2_k127_548050_3	717606.PaecuDRAFT_1531	1.426e-85	302.0	COG2244@1|root,COG2244@2|Bacteria,1V929@1239|Firmicutes,4HKDX@91061|Bacilli	91061|Bacilli	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS2_k127_548050_0	945713.IALB_2868	5.327e-253	787.0	COG2986@1|root,COG2986@2|Bacteria	2|Bacteria	E	ammonia-lyase activity	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
LZS2_k127_548050_5	1340434.AXVA01000006_gene4351	6.911e-52	192.0	COG1834@1|root,COG1834@2|Bacteria,1TRPV@1239|Firmicutes,4H9YU@91061|Bacilli	91061|Bacilli	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
LZS2_k127_548050_11	1519439.JPJG01000058_gene2044	6.036e-06	55.0	COG5660@1|root,COG5660@2|Bacteria,1UX41@1239|Firmicutes,25KVF@186801|Clostridia,2N7WI@216572|Oscillospiraceae	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS2_k127_548050_6	1121937.AUHJ01000001_gene600	5.119e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,465S4@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_548050_9	861299.J421_6360	5.189e-07	62.0	2F0M3@1|root,33TPR@2|Bacteria,1ZUAZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_548050_13	926550.CLDAP_17500	0.0001988	55.0	COG2706@1|root,COG2931@1|root,COG5337@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,LTD,VCBS
LZS2_k127_548050_7	179408.Osc7112_0245	3.044e-23	117.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
LZS2_k127_548050_12	96561.Dole_0488	7.684e-05	52.0	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	ppdC	-	-	ko:K02671,ko:K02681,ko:K10927	ko05111,map05111	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	N_methyl,T2SSppdC
LZS2_k127_548050_10	933262.AXAM01000061_gene1668	5.833e-06	55.0	COG4970@1|root,COG4970@2|Bacteria,1Q0DU@1224|Proteobacteria,42W7A@68525|delta/epsilon subdivisions,2WS6U@28221|Deltaproteobacteria,2MKVN@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
LZS2_k127_548050_2	945713.IALB_2155	5.793e-138	455.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	iPC815.YPO3230,iSBO_1134.SBO_0243	M20_dimer,Peptidase_M20
LZS2_k127_548050_1	1499967.BAYZ01000173_gene5813	5.17e-196	634.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
LZS2_k127_548050_8	880073.Calab_0992	1.861e-15	77.0	COG2006@1|root,COG2006@2|Bacteria,2NQF7@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_5498238_0	1121104.AQXH01000001_gene1413	6.352e-153	513.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_5498677_4	1382304.JNIL01000001_gene2422	8.302e-05	54.0	COG0457@1|root,COG0457@2|Bacteria	1382304.JNIL01000001_gene2422|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5498677_3	1280692.AUJL01000007_gene1304	1.094e-11	67.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,36DPR@31979|Clostridiaceae	186801|Clostridia	P	potassium uptake protein, TrkH family	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS2_k127_5498677_1	999411.HMPREF1092_01161	4.271e-16	81.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,36DGN@31979|Clostridiaceae	186801|Clostridia	P	Potassium uptake protein	ktrC	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
LZS2_k127_5498677_0	945713.IALB_1872	8.788e-181	575.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS2_k127_5498677_2	518766.Rmar_1517	9.053e-12	78.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,1FJ24@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
LZS2_k127_5505288_4	644282.Deba_2103	3.799e-61	219.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM oxidoreductase domain protein	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS2_k127_5505288_3	1123288.SOV_3c03730	5.074e-85	289.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes	909932|Negativicutes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep,Hexapep_2
LZS2_k127_5505288_0	1379698.RBG1_1C00001G1649	1.383e-132	436.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
LZS2_k127_5505288_1	1379698.RBG1_1C00001G1848	1.004e-103	347.0	COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	ic_1306.c0216	Hexapep,Hexapep_2,LpxD
LZS2_k127_5505288_5	1379698.RBG1_1C00001G1847	3.714e-36	143.0	COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
LZS2_k127_5505288_2	1379698.RBG1_1C00001G1846	5.53e-102	354.0	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS2_k127_5520629_1	290317.Cpha266_0257	3.155e-121	396.0	COG4974@1|root,COG4974@2|Bacteria,1FESB@1090|Chlorobi	1090|Chlorobi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS2_k127_5520629_9	338963.Pcar_2645	3.043e-17	85.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,42N7M@68525|delta/epsilon subdivisions,2WIJ0@28221|Deltaproteobacteria,43U3N@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS2_k127_5520629_10	1232437.KL661957_gene2916	5.857e-17	84.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,42VWR@68525|delta/epsilon subdivisions,2WS4U@28221|Deltaproteobacteria,2MKU4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
LZS2_k127_5520629_2	517418.Ctha_2708	9.302e-120	399.0	COG1538@1|root,COG1538@2|Bacteria,1FD6I@1090|Chlorobi	1090|Chlorobi	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS2_k127_5520629_3	517418.Ctha_2707	5.601e-97	328.0	COG0845@1|root,COG0845@2|Bacteria,1FE89@1090|Chlorobi	1090|Chlorobi	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS2_k127_5520629_0	517418.Ctha_2706	0.0	1513.0	COG0841@1|root,COG0841@2|Bacteria,1FDJ5@1090|Chlorobi	1090|Chlorobi	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS2_k127_5520629_8	517418.Ctha_2705	6.834e-19	89.0	29GHY@1|root,303FP@2|Bacteria,1FFD5@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5520629_4	502025.Hoch_2634	8.614e-83	282.0	COG0778@1|root,COG0778@2|Bacteria,1PG5G@1224|Proteobacteria,431RK@68525|delta/epsilon subdivisions,2WWKP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5520629_7	1499502.EV12_2045	2.449e-33	146.0	COG3315@1|root,COG3315@2|Bacteria,1GMZ3@1117|Cyanobacteria,1MNHE@1212|Prochloraceae	1117|Cyanobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
LZS2_k127_5520629_6	335543.Sfum_0229	1.183e-62	221.0	COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,43BDS@68525|delta/epsilon subdivisions,2X6SC@28221|Deltaproteobacteria,2MS1B@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS2_k127_5520629_5	204669.Acid345_1614	1.538e-65	231.0	COG5587@1|root,COG5587@2|Bacteria,3Y4D4@57723|Acidobacteria,2JJ1B@204432|Acidobacteriia	204432|Acidobacteriia	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
LZS2_k127_5535574_15	765869.BDW_05310	2.814e-18	85.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2MSN5@213481|Bdellovibrionales,2WJCE@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
LZS2_k127_5535574_12	635013.TherJR_1384	4.147e-31	124.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,262DU@186807|Peptococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
LZS2_k127_5535574_9	1239962.C943_02949	5.18e-68	242.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
LZS2_k127_5535574_11	1242864.D187_006283	9.868e-50	189.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2YVB2@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
LZS2_k127_5535574_14	269799.Gmet_1587	2.361e-26	111.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42U0Y@68525|delta/epsilon subdivisions,2WR00@28221|Deltaproteobacteria,43V4Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
LZS2_k127_5535574_16	457570.Nther_1260	3.238e-17	84.0	COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,24QJY@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
LZS2_k127_5535574_19	1150398.JIBJ01000009_gene370	1.715e-07	53.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,1W85P@1268|Micrococcaceae	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
LZS2_k127_5535574_0	880073.Calab_3554	8.079e-194	632.0	COG0532@1|root,COG0532@2|Bacteria,2NNRG@2323|unclassified Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
LZS2_k127_5535574_5	1379698.RBG1_1C00001G1152	2.915e-114	384.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
LZS2_k127_5535574_13	1415780.JPOG01000001_gene1646	1.422e-29	124.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,1X5YX@135614|Xanthomonadales	135614|Xanthomonadales	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
LZS2_k127_5535574_8	1379698.RBG1_1C00001G0436	4.493e-77	268.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS2_k127_5535574_2	1379698.RBG1_1C00001G0435	1.074e-169	597.0	COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N,SprA_N
LZS2_k127_5535574_7	1379698.RBG1_1C00001G1858	1.348e-86	304.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
LZS2_k127_5535574_10	1379698.RBG1_1C00001G1857	4.127e-62	227.0	COG0795@1|root,COG0795@2|Bacteria,2NPHN@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
LZS2_k127_5535574_18	234267.Acid_1509	3.982e-16	92.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5535574_1	1499967.BAYZ01000190_gene3862	3.159e-193	610.0	COG0499@1|root,COG0499@2|Bacteria,2NNQE@2323|unclassified Bacteria	2|Bacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS2_k127_5535574_4	304371.MCP_1463	1.633e-152	490.0	COG0192@1|root,arCOG07444@2157|Archaea	2157|Archaea	H	S-adenosylmethionine synthetase, C-terminal domain	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
LZS2_k127_5535574_6	1519464.HY22_02585	3.48e-103	347.0	COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS2_k127_5535574_3	273068.TTE2334	2.279e-162	530.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
LZS2_k127_5535574_17	349741.Amuc_1757	1.48e-16	83.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia,2IUM2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
LZS2_k127_5535574_20	610130.Closa_0205	8.127e-07	56.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,24A0K@186801|Clostridia	186801|Clostridia	G	PTS system mannose fructose sorbose family IID component	manZ2	-	-	ko:K02795,ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276,M00278	R02630,R04076	RC00017,RC01069,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1,4.A.6.1.3	-	-	EII-Sor,EIID-AGA
LZS2_k127_5547892_0	370438.PTH_1427	6.659e-139	464.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,260IK@186807|Peptococcaceae	186801|Clostridia	J	Elongation factor Tu domain 2	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
LZS2_k127_5547892_1	1191523.MROS_2277	3.489e-138	456.0	COG0766@1|root,COG0766@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
LZS2_k127_5547892_2	1316936.K678_14332	2.324e-35	139.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,2JQMD@204441|Rhodospirillales	204441|Rhodospirillales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
LZS2_k127_5555098_12	880073.Calab_0921	2.763e-20	95.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS2_k127_5555098_7	1232410.KI421424_gene1591	3.604e-51	193.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,42R83@68525|delta/epsilon subdivisions,2WN00@28221|Deltaproteobacteria,43RXQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
LZS2_k127_5555098_0	96561.Dole_2580	5.454e-288	892.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MHY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
LZS2_k127_5555098_3	880073.Calab_3525	1.029e-171	572.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
LZS2_k127_5555098_5	880073.Calab_3524	1.066e-95	325.0	2CF1V@1|root,2Z8M1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4876
LZS2_k127_5555098_9	316274.Haur_2022	3.895e-35	155.0	COG4447@1|root,COG4447@2|Bacteria,2G9IJ@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5555098_14	945713.IALB_3128	2.187e-15	91.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
LZS2_k127_5555098_2	1047013.AQSP01000075_gene1424	8.535e-192	638.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
LZS2_k127_5555098_15	243231.GSU1776	8.085e-12	73.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,42ZXF@68525|delta/epsilon subdivisions,2WV6V@28221|Deltaproteobacteria,43UYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Pfam:N_methyl_2	oxpG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
LZS2_k127_5555098_8	945713.IALB_2137	1.23e-45	177.0	2AMSR@1|root,31CP7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5555098_6	331678.Cphamn1_2460	5.705e-70	240.0	COG1592@1|root,COG1592@2|Bacteria,1FE9N@1090|Chlorobi	1090|Chlorobi	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS2_k127_5555098_1	290317.Cpha266_1570	2.71e-198	628.0	COG0069@1|root,COG1773@1|root,COG0069@2|Bacteria,COG1773@2|Bacteria,1FDGS@1090|Chlorobi	1090|Chlorobi	C	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rubredoxin
LZS2_k127_5555098_11	755732.Fluta_0697	1.882e-23	113.0	COG3291@1|root,COG3291@2|Bacteria,4NM0P@976|Bacteroidetes,1I0CF@117743|Flavobacteriia,2PAUX@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M14
LZS2_k127_5555098_16	649638.Trad_0217	0.0001884	53.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,PA14,PKD
LZS2_k127_5555098_4	580340.Tlie_0145	1.33e-142	465.0	COG3844@1|root,COG3844@2|Bacteria,3TA91@508458|Synergistetes	508458|Synergistetes	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
LZS2_k127_5596599_4	639282.DEFDS_0158	5.007e-46	171.0	COG0669@1|root,COG0669@2|Bacteria,2GFI7@200930|Deferribacteres	200930|Deferribacteres	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS2_k127_5596599_7	1385510.N781_12815	1.14e-20	100.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,2YA9U@289201|Pontibacillus	91061|Bacilli	L	Ribosomal RNA large subunit methyltransferase D, RlmJ	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
LZS2_k127_5596599_3	903818.KI912269_gene477	9.453e-61	233.0	COG4796@1|root,COG4796@2|Bacteria,3Y98D@57723|Acidobacteria	57723|Acidobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
LZS2_k127_5596599_8	671143.DAMO_1410	6.348e-20	97.0	COG3167@1|root,COG3167@2|Bacteria,2NPUF@2323|unclassified Bacteria	2|Bacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
LZS2_k127_5596599_10	56780.SYN_01775	8.37e-06	55.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria,2MQQG@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
LZS2_k127_5596599_0	379066.GAU_2518	4.178e-78	273.0	COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
LZS2_k127_5596599_1	56780.SYN_00575	2.914e-64	229.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,2MQEJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
LZS2_k127_5596599_6	204669.Acid345_1573	4.936e-23	113.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_1573|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5596599_5	1265505.ATUG01000003_gene184	1.032e-35	146.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2MPXF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
LZS2_k127_5596599_2	215803.DB30_5162	2.456e-62	227.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YUS3@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_5660384_3	926561.KB900617_gene1859	8.825e-58	217.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WB91@53433|Halanaerobiales	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
LZS2_k127_5660384_2	1158318.ATXC01000001_gene1441	1.501e-88	297.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS2_k127_5660384_0	1121468.AUBR01000001_gene485	1.811e-163	524.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,42EU3@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
LZS2_k127_5660384_1	404589.Anae109_3418	5.001e-115	382.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YU3Z@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS2_k127_5685176_8	1218173.BALCAV_0220920	3.191e-13	76.0	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,4HGNB@91061|Bacilli,1ZGEX@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_5685176_6	290317.Cpha266_1001	1.989e-40	154.0	COG1765@1|root,COG1765@2|Bacteria,1FE41@1090|Chlorobi	1090|Chlorobi	O	PFAM OsmC family protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
LZS2_k127_5685176_4	378806.STAUR_4781	1.186e-77	271.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,2YUHA@29|Myxococcales	28221|Deltaproteobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_5685176_1	378806.STAUR_4436	4.506e-101	342.0	COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria,2YUM5@29|Myxococcales	28221|Deltaproteobacteria	E	Sarcosine oxidase	soxB	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
LZS2_k127_5685176_7	1121430.JMLG01000001_gene2300	3.386e-17	84.0	COG1251@1|root,COG1251@2|Bacteria,1VI2I@1239|Firmicutes,24TGP@186801|Clostridia,265VU@186807|Peptococcaceae	186801|Clostridia	C	PFAM BFD-like 2Fe-2S -binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
LZS2_k127_5685176_5	589924.Ferp_2556	1.684e-48	191.0	COG0446@1|root,arCOG01294@2157|Archaea,2XUFI@28890|Euryarchaeota,246RK@183980|Archaeoglobi	183980|Archaeoglobi	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Pyr_redox_2
LZS2_k127_5685176_2	517418.Ctha_2620	1.907e-100	344.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_5685176_3	926562.Oweho_1655	3.018e-88	317.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1HWQI@117743|Flavobacteriia,2PA72@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_5685176_0	1408473.JHXO01000004_gene195	2.656e-105	351.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
LZS2_k127_5709986_0	653733.Selin_0177	3.835e-125	413.0	COG0104@1|root,COG0104@2|Bacteria	2|Bacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889	Adenylsucc_synt
LZS2_k127_5709986_1	485916.Dtox_0809	2.838e-81	305.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS2_k127_5709986_2	867903.ThesuDRAFT_00167	8.442e-48	178.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3WCIP@538999|Clostridiales incertae sedis	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
LZS2_k127_5742887_3	1499967.BAYZ01000016_gene6500	6.787e-40	159.0	COG3823@1|root,COG3823@2|Bacteria	2|Bacteria	O	gene silencing by RNA	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
LZS2_k127_5742887_1	626939.HMPREF9443_01958	1.661e-131	429.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H2VM@909932|Negativicutes	909932|Negativicutes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
LZS2_k127_5742887_2	1128421.JAGA01000001_gene2034	3.698e-54	200.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
LZS2_k127_5742887_0	1125863.JAFN01000001_gene1129	1.033e-163	535.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
LZS2_k127_5744578_4	880073.Calab_0143	0.0001239	55.0	COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria	2|Bacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
LZS2_k127_5744578_2	443143.GM18_0409	1.142e-13	80.0	COG1572@1|root,COG3291@1|root,COG1572@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.78	ko:K01218,ko:K13276	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH26	-	CARDB,CHB_HEX_C_1,F5_F8_type_C,Laminin_G_3
LZS2_k127_5744578_3	1121468.AUBR01000007_gene248	2.265e-11	74.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,24MPI@186801|Clostridia,42GV3@68295|Thermoanaerobacterales	186801|Clostridia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
LZS2_k127_5744578_1	1379698.RBG1_1C00001G0748	2.099e-90	322.0	COG0308@1|root,COG0308@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
LZS2_k127_5744578_0	880073.Calab_3450	3.63e-168	561.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
LZS2_k127_5765961_4	861299.J421_0340	3.506e-62	225.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
LZS2_k127_5765961_1	404589.Anae109_3842	2.118e-249	795.0	COG1164@1|root,COG1164@2|Bacteria,1Q3C4@1224|Proteobacteria,4393F@68525|delta/epsilon subdivisions,2X49B@28221|Deltaproteobacteria,2YYJ7@29|Myxococcales	28221|Deltaproteobacteria	E	Oligoendopeptidase f	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5765961_0	945713.IALB_1079	1.596e-305	945.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
LZS2_k127_5765961_2	945713.IALB_1080	2.788e-223	696.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_5765961_3	945713.IALB_1874	2.932e-219	693.0	COG4690@1|root,COG4690@2|Bacteria	2|Bacteria	E	dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
LZS2_k127_5765961_6	909663.KI867150_gene1074	1.462e-40	161.0	COG1917@1|root,COG1917@2|Bacteria,1N2JS@1224|Proteobacteria,42TR3@68525|delta/epsilon subdivisions,2WQ4M@28221|Deltaproteobacteria,2MSCX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS2_k127_5765961_5	1232437.KL662020_gene724	1.003e-52	191.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2WNEN@28221|Deltaproteobacteria,2MK2I@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
LZS2_k127_5765961_8	1196322.A370_04997	1.609e-07	59.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,36VT5@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_5765961_7	1121930.AQXG01000001_gene1204	1.968e-37	153.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS2_k127_5766777_0	123214.PERMA_0503	2.442e-51	200.0	COG0457@1|root,COG0457@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS2_k127_5766777_1	1379270.AUXF01000002_gene1168	4.586e-39	155.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_5766777_2	1340434.AXVA01000031_gene2837	1.351e-05	55.0	COG5662@1|root,COG5662@2|Bacteria,1V6C7@1239|Firmicutes,4HFTK@91061|Bacilli,1ZE1K@1386|Bacillus	91061|Bacilli	K	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation	rsiW	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
LZS2_k127_5778366_9	945543.VIBR0546_00515	1.897e-29	130.0	COG1596@1|root,COG1596@2|Bacteria,1PK0J@1224|Proteobacteria,1RM8V@1236|Gammaproteobacteria,1XUG8@135623|Vibrionales	135623|Vibrionales	M	Periplasmic protein involved in polysaccharide export	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
LZS2_k127_5778366_2	1232410.KI421414_gene2855	1.277e-106	355.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria,43T7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS2_k127_5778366_1	234267.Acid_4597	2.66e-175	559.0	COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS2_k127_5778366_6	401526.TcarDRAFT_0275	3.155e-45	177.0	COG2199@1|root,COG3706@2|Bacteria,1V469@1239|Firmicutes,4H4YE@909932|Negativicutes	909932|Negativicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,PAS_9
LZS2_k127_5778366_7	1242864.D187_002048	2.807e-42	168.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,43B0D@68525|delta/epsilon subdivisions,2WRKF@28221|Deltaproteobacteria,2YV99@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
LZS2_k127_5778366_8	593750.Metfor_2198	1.624e-40	164.0	COG2208@1|root,arCOG02362@1|root,arCOG02362@2157|Archaea,arCOG06893@2157|Archaea,2Y2MD@28890|Euryarchaeota	2157|Archaea	T	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
LZS2_k127_5778366_3	194439.CT1618	9.553e-93	327.0	COG0497@1|root,COG0497@2|Bacteria,1FDSV@1090|Chlorobi	1090|Chlorobi	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
LZS2_k127_5778366_5	1121468.AUBR01000002_gene652	1.005e-54	202.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,42FQN@68295|Thermoanaerobacterales	186801|Clostridia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
LZS2_k127_5778366_0	401526.TcarDRAFT_1596	2.727e-218	694.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H236@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
LZS2_k127_5778366_11	3827.XP_004502318.1	4.208e-14	78.0	COG1963@1|root,2RZ3E@2759|Eukaryota,37TQD@33090|Viridiplantae,3GHZD@35493|Streptophyta,4JP4J@91835|fabids	35493|Streptophyta	S	membrane protein YuiD-like	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
LZS2_k127_5778366_4	767817.Desgi_2603	4.729e-59	215.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,2606Y@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS2_k127_5778366_12	1123253.AUBD01000007_gene671	3.579e-11	66.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1X7MG@135614|Xanthomonadales	135614|Xanthomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
LZS2_k127_5778366_10	1392501.JIAC01000001_gene1738	1.396e-18	91.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4H31X@909932|Negativicutes	909932|Negativicutes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
LZS2_k127_5780973_2	351160.LRC544	6.929e-18	96.0	COG0438@1|root,arCOG01403@2157|Archaea,2Y8BE@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_5780973_0	696369.KI912183_gene742	7.128e-141	459.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,2601M@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
LZS2_k127_5780973_1	1379698.RBG1_1C00001G1562	3.495e-117	393.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
LZS2_k127_5785888_2	396588.Tgr7_1034	2.145e-79	272.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
LZS2_k127_5785888_0	1122179.KB890448_gene3001	4.495e-100	334.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1IQDT@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
LZS2_k127_5785888_1	443143.GM18_0868	7.369e-89	299.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
LZS2_k127_5823993_5	459349.CLOAM1745	2.015e-20	94.0	COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria	2|Bacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
LZS2_k127_5823993_0	861299.J421_2541	2.028e-110	376.0	COG4166@1|root,COG4166@2|Bacteria,1ZSMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_5823993_1	379066.GAU_0606	3.943e-95	322.0	COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_5823993_3	1123288.SOV_3c00820	1.585e-79	287.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H1VB@909932|Negativicutes	909932|Negativicutes	EP	Permease	oppC	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
LZS2_k127_5823993_4	243090.RB11119	1.318e-41	170.0	COG0791@1|root,COG0791@2|Bacteria,2J4V8@203682|Planctomycetes	203682|Planctomycetes	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
LZS2_k127_5823993_8	880073.Calab_0119	2.358e-07	63.0	2F9BU@1|root,341NU@2|Bacteria,2NR9C@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5823993_6	1089553.Tph_c17370	1.014e-18	99.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,42GFH@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Rhomboid family protein	GlpG	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS2_k127_5823993_2	1121468.AUBR01000048_gene1658	1.887e-89	310.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,42FQX@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
LZS2_k127_5823993_7	1385511.N783_08775	3.088e-08	57.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,2Y9J6@289201|Pontibacillus	91061|Bacilli	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
LZS2_k127_5872392_10	1071073.KI530537_gene1944	5.684e-06	57.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus	91061|Bacilli	CO	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c	resA	GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_5872392_3	1191523.MROS_0148	1.118e-99	338.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
LZS2_k127_5872392_1	945713.IALB_0266	1.109e-189	604.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
LZS2_k127_5872392_4	65093.PCC7418_1870	1.048e-78	271.0	COG0500@1|root,COG2226@2|Bacteria,1GQEQ@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_5872392_9	1165841.SULAR_02403	6.949e-09	61.0	2DFKD@1|root,2ZS7E@2|Bacteria,1P5EA@1224|Proteobacteria	1224|Proteobacteria	S	Pfam:DUF1049	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
LZS2_k127_5872392_0	880073.Calab_1714	4.256e-212	678.0	COG2866@1|root,COG2866@2|Bacteria,2NQT6@2323|unclassified Bacteria	2|Bacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
LZS2_k127_5872392_5	521045.Kole_0192	9.337e-76	278.0	COG5276@1|root,COG5276@2|Bacteria,2GDIA@200918|Thermotogae	200918|Thermotogae	S	PFAM LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
LZS2_k127_5872392_8	330214.NIDE0017	4.653e-30	122.0	COG3369@1|root,COG3369@2|Bacteria,3J1A6@40117|Nitrospirae	40117|Nitrospirae	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
LZS2_k127_5872392_2	1123371.ATXH01000024_gene1026	3.117e-107	355.0	COG1313@1|root,COG1313@2|Bacteria,2GH0B@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
LZS2_k127_5872392_6	1415779.JOMH01000001_gene19	1.178e-36	159.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,1RSAD@1236|Gammaproteobacteria,1X474@135614|Xanthomonadales	135614|Xanthomonadales	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_5872392_7	693661.Arcve_0553	8.714e-31	140.0	COG3379@1|root,arCOG01377@2157|Archaea,2XUWW@28890|Euryarchaeota,2468N@183980|Archaeoglobi	183980|Archaeoglobi	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_5874866_2	304371.MCP_0432	1.247e-39	148.0	COG0433@1|root,arCOG09167@1|root,arCOG00280@2157|Archaea,arCOG00286@2157|Archaea,arCOG09167@2157|Archaea	2157|Archaea	P	protein kinase activity	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
LZS2_k127_5874866_1	880072.Desac_0212	2.07e-60	214.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria,2MRIV@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Large-conductance mechanosensitive channel, MscL	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
LZS2_k127_5874866_0	96561.Dole_1374	1.084e-195	627.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2MHT0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS2_k127_5874866_3	1125863.JAFN01000001_gene1924	6.988e-14	75.0	COG1225@1|root,COG1225@2|Bacteria,1R0DK@1224|Proteobacteria,43CW6@68525|delta/epsilon subdivisions,2X846@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_5874866_4	1408813.AYMG01000013_gene1321	0.000203	53.0	COG0526@1|root,COG0526@2|Bacteria,4NI7U@976|Bacteroidetes,1IPS3@117747|Sphingobacteriia	976|Bacteroidetes	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_5882578_1	572546.Arcpr_1033	1.495e-64	229.0	COG0327@1|root,arCOG04454@2157|Archaea,2XT5G@28890|Euryarchaeota,246Y5@183980|Archaeoglobi	183980|Archaeoglobi	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
LZS2_k127_5882578_0	1123371.ATXH01000012_gene1458	2.124e-72	280.0	COG3604@1|root,COG3604@2|Bacteria,2GGRI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	GAF domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
LZS2_k127_5882578_5	1158345.JNLL01000001_gene902	4.823e-11	71.0	COG1579@1|root,COG1579@2|Bacteria,2G4TK@200783|Aquificae	200783|Aquificae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
LZS2_k127_5882578_3	1319815.HMPREF0202_02329	2.931e-28	119.0	COG1762@1|root,COG1762@2|Bacteria,379WR@32066|Fusobacteria	32066|Fusobacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
LZS2_k127_5882578_2	1408473.JHXO01000001_gene2069	3.305e-61	222.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,2FNY9@200643|Bacteroidia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
LZS2_k127_5882578_4	1191523.MROS_0141	3.837e-18	95.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	waaC	-	-	ko:K02841,ko:K02843,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS2_k127_5900735_0	945713.IALB_3167	6.439e-159	522.0	COG0457@1|root,COG0457@2|Bacteria	945713.IALB_3167|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5900735_1	1313421.JHBV01000041_gene3469	4.674e-153	502.0	COG0405@1|root,COG0405@2|Bacteria,4NF2H@976|Bacteroidetes,1IP46@117747|Sphingobacteriia	976|Bacteroidetes	E	PFAM Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS2_k127_5937885_3	880073.Calab_3518	6.756e-06	54.0	COG0348@1|root,COG0348@2|Bacteria,2NQ06@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4,Fer4_5
LZS2_k127_5937885_0	1449126.JQKL01000033_gene1179	7.305e-44	170.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,26BXQ@186813|unclassified Clostridiales	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5
LZS2_k127_5937885_1	1089550.ATTH01000001_gene1826	3.711e-33	143.0	COG2885@1|root,COG2885@2|Bacteria,4NKCW@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS2_k127_5937885_2	36875.HQ29_02980	3.29e-17	92.0	COG1186@1|root,COG1186@2|Bacteria,4NJQS@976|Bacteroidetes	976|Bacteroidetes	J	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
LZS2_k127_5995796_11	1121930.AQXG01000001_gene1202	5.406e-38	147.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_5995796_9	944480.ATUV01000001_gene877	1.411e-41	163.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2M7A3@213113|Desulfurellales	28221|Deltaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS2_k127_5995796_8	713586.KB900536_gene644	1.584e-42	158.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1SA44@1236|Gammaproteobacteria,1X24M@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
LZS2_k127_5995796_15	398578.Daci_1177	2.021e-18	96.0	COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,2VY0W@28216|Betaproteobacteria,4AHAS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
LZS2_k127_5995796_2	484770.UFO1_1578	4.845e-104	359.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS2_k127_5995796_4	1499967.BAYZ01000054_gene4817	1.749e-82	285.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_5995796_6	269799.Gmet_1236	1.358e-69	247.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,43TPC@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_5995796_3	290397.Adeh_4045	2.19e-95	326.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
LZS2_k127_5995796_14	204536.SULAZ_1583	6.918e-23	102.0	COG1324@1|root,COG1324@2|Bacteria,2G58A@200783|Aquificae	200783|Aquificae	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
LZS2_k127_5995796_7	1480694.DC28_07915	3.488e-43	170.0	COG1752@1|root,COG1752@2|Bacteria,2J6JW@203691|Spirochaetes	203691|Spirochaetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
LZS2_k127_5995796_1	1191523.MROS_0532	4.648e-151	492.0	COG1690@1|root,COG1690@2|Bacteria	2|Bacteria	S	RNA ligase activity	rtcB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
LZS2_k127_5995796_0	880073.Calab_2784	1.617e-154	506.0	COG1164@1|root,COG1164@2|Bacteria,2NQ8K@2323|unclassified Bacteria	2|Bacteria	E	Oligoendopeptidase f	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2,Peptidase_M3
LZS2_k127_5995796_13	383372.Rcas_2505	1.885e-29	135.0	COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_5995796_10	880073.Calab_0082	5.03e-40	157.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_5995796_12	1480694.DC28_03280	9.683e-36	143.0	COG0393@1|root,COG0393@2|Bacteria	2|Bacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS2_k127_5995796_5	880073.Calab_0865	3.384e-77	268.0	COG0491@1|root,COG0491@2|Bacteria,2NPRD@2323|unclassified Bacteria	2|Bacteria	S	Metallo-beta-lactamase superfamily	ytnP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_6023339_0	518766.Rmar_0733	2.98e-11	77.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,1FJ03@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS2_k127_6027254_2	498761.HM1_2458	6.65e-117	407.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
LZS2_k127_6027254_1	477974.Daud_0484	8.631e-128	415.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,24AU0@186801|Clostridia,2604H@186807|Peptococcaceae	186801|Clostridia	J	PFAM glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
LZS2_k127_6027254_10	1229203.KI301992_gene644	5.043e-09	68.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,3UWH5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
LZS2_k127_6027254_5	1048983.EL17_04620	6.164e-89	309.0	COG2239@1|root,COG2239@2|Bacteria,4NGGN@976|Bacteroidetes,47JTX@768503|Cytophagia	976|Bacteroidetes	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS2_k127_6027254_7	373903.Hore_12550	4.49e-45	170.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia,3WBT4@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
LZS2_k127_6027254_6	574087.Acear_0620	9.18e-66	241.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
LZS2_k127_6027254_8	1038867.AXAY01000008_gene620	2.614e-18	91.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,3JWAC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
LZS2_k127_6027254_3	340099.Teth39_1368	2.256e-106	374.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,42EY4@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
LZS2_k127_6027254_4	635013.TherJR_2423	9.258e-99	331.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,260MI@186807|Peptococcaceae	186801|Clostridia	T	PFAM PhoH family protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
LZS2_k127_6027254_11	1226322.HMPREF1545_01926	2.76e-05	54.0	COG1652@1|root,COG2365@1|root,COG1652@2|Bacteria,COG2365@2|Bacteria,1UX3Z@1239|Firmicutes,25QBE@186801|Clostridia,2N8S9@216572|Oscillospiraceae	186801|Clostridia	T	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_6027254_9	868864.Dester_0658	1.515e-12	76.0	COG1652@1|root,COG2433@1|root,COG1652@2|Bacteria,COG2433@2|Bacteria,2G4TM@200783|Aquificae	200783|Aquificae	S	PFAM Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS2_k127_6027254_0	273068.TTE1231	1.286e-184	595.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,42EM9@68295|Thermoanaerobacterales	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
LZS2_k127_6101175_8	331678.Cphamn1_1658	1.033e-16	90.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
LZS2_k127_6101175_6	706587.Desti_4646	5.394e-21	99.0	COG2259@1|root,COG2259@2|Bacteria,1RIFW@1224|Proteobacteria,42UDR@68525|delta/epsilon subdivisions,2WR26@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Methylamine utilisation protein MauE	-	-	-	-	-	-	-	-	-	-	-	-	MauE
LZS2_k127_6101175_3	1033810.HLPCO_002908	7.627e-44	186.0	COG3420@1|root,COG4932@1|root,COG5604@1|root,COG3420@2|Bacteria,COG4932@2|Bacteria,COG5604@2|Bacteria	2|Bacteria	DZ	domain, Protein	bhp	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	Beta_helix,DUF5011,Flg_new,Gram_pos_anchor,He_PIG,YSIRK_signal
LZS2_k127_6101175_7	459349.CLOAM1790	1.817e-19	106.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
LZS2_k127_6101175_10	880073.Calab_2064	2.827e-05	55.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
LZS2_k127_6101175_11	1267533.KB906733_gene3613	0.0001961	51.0	COG4796@1|root,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria,2JHZH@204432|Acidobacteriia	204432|Acidobacteriia	U	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
LZS2_k127_6101175_0	522306.CAP2UW1_0858	8.552e-157	505.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VMX7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	algD	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS2_k127_6101175_2	1089548.KI783301_gene2313	7.705e-51	198.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,4HBYI@91061|Bacilli,3WFUU@539002|Bacillales incertae sedis	91061|Bacilli	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_6101175_4	526222.Desal_3470	3.578e-37	161.0	COG5360@1|root,COG5360@2|Bacteria,1MZ5X@1224|Proteobacteria,42PG1@68525|delta/epsilon subdivisions,2WP6V@28221|Deltaproteobacteria,2MAC3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
LZS2_k127_6101175_5	459349.CLOAM0243	9.247e-37	156.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS2_k127_6101175_9	246197.MXAN_0261	9.989e-14	81.0	COG1396@1|root,COG1762@1|root,COG1396@2|Bacteria,COG1762@2|Bacteria,1NBG9@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_31,PTS_EIIA_2
LZS2_k127_6101175_1	690850.Desaf_3423	9.552e-85	289.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria,2M93A@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_6130351_3	1304885.AUEY01000061_gene2832	4.851e-20	105.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6130351_2	459349.CLOAM0631	3.658e-20	105.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
LZS2_k127_6130351_0	886293.Sinac_0560	5.833e-55	209.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	mgsA	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat,DSPc,MGS
LZS2_k127_6130351_1	1280674.AUJK01000002_gene1353	1.242e-26	111.0	COG0484@1|root,COG0484@2|Bacteria,4NF41@976|Bacteroidetes,2FPHH@200643|Bacteroidia	976|Bacteroidetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS2_k127_6138988_1	2423.NA23_0205420	1.422e-123	403.0	COG1012@1|root,COG1012@2|Bacteria,2GCJA@200918|Thermotogae	200918|Thermotogae	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
LZS2_k127_6138988_3	266117.Rxyl_0794	2.75e-22	98.0	COG1254@1|root,COG1254@2|Bacteria,2IT6J@201174|Actinobacteria,4CTJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
LZS2_k127_6138988_4	644281.MFS40622_0958	5.629e-11	71.0	COG1371@1|root,arCOG04055@2157|Archaea,2XXRX@28890|Euryarchaeota,23R02@183939|Methanococci	183939|Methanococci	S	Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently	-	-	-	-	-	-	-	-	-	-	-	-	Archease
LZS2_k127_6138988_2	195253.Syn6312_0709	1.187e-32	139.0	COG1216@1|root,COG1216@2|Bacteria,1G705@1117|Cyanobacteria,1H22C@1129|Synechococcus	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
LZS2_k127_6138988_0	1121405.dsmv_0379	1.478e-143	467.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
LZS2_k127_6140401_0	404589.Anae109_2842	1.001e-13	86.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
LZS2_k127_6140401_1	404380.Gbem_2718	1.085e-11	79.0	COG1361@1|root,COG2885@1|root,COG4719@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,COG4719@2|Bacteria,1QW22@1224|Proteobacteria	1224|Proteobacteria	M	Ompa motb domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA,SdrD_B
LZS2_k127_6147330_3	706587.Desti_4353	1.258e-53	194.0	COG0517@1|root,COG0517@2|Bacteria,1RKZ2@1224|Proteobacteria,42SYQ@68525|delta/epsilon subdivisions,2WP9E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS2_k127_6147330_0	1265505.ATUG01000001_gene2868	2.955e-227	713.0	COG1055@1|root,COG1055@2|Bacteria,1QUC0@1224|Proteobacteria,42NUZ@68525|delta/epsilon subdivisions,2WJNH@28221|Deltaproteobacteria,2MPNS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS2_k127_6147330_2	177437.HRM2_40350	8.929e-109	365.0	COG0745@1|root,COG0745@2|Bacteria,1NE8H@1224|Proteobacteria,42NEH@68525|delta/epsilon subdivisions,2WK1M@28221|Deltaproteobacteria,2MHU4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2,Response_reg
LZS2_k127_6147330_1	439235.Dalk_2933	2.626e-177	573.0	COG4191@1|root,COG4191@2|Bacteria,1R7KQ@1224|Proteobacteria,42PAP@68525|delta/epsilon subdivisions,2WITB@28221|Deltaproteobacteria,2MHP3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
LZS2_k127_6147330_4	525897.Dbac_1807	2.156e-33	132.0	COG2204@1|root,COG2204@2|Bacteria,1P58Q@1224|Proteobacteria,430GN@68525|delta/epsilon subdivisions,2WVMH@28221|Deltaproteobacteria,2MCHQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_6147330_5	933262.AXAM01000002_gene551	1.05e-31	132.0	COG4191@1|root,COG4191@2|Bacteria,1NC2K@1224|Proteobacteria,42WDG@68525|delta/epsilon subdivisions,2WRNM@28221|Deltaproteobacteria,2MKFV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HisKA
LZS2_k127_6158419_0	653733.Selin_1582	1.056e-174	561.0	COG0439@1|root,COG0439@2|Bacteria	2|Bacteria	I	biotin carboxylase activity	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS2_k127_6158419_1	243231.GSU0146	1.015e-121	401.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,43TYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS2_k127_6158419_3	283942.IL2285	2.812e-36	142.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,2QG4K@267893|Idiomarinaceae	1236|Gammaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iYL1228.KPN_03664	Biotin_lipoyl
LZS2_k127_6158419_2	635013.TherJR_1731	1.246e-64	229.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,261EB@186807|Peptococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
LZS2_k127_6158419_5	1379698.RBG1_1C00001G1748	2.566e-08	65.0	COG0457@1|root,COG0457@2|Bacteria,2NS1B@2323|unclassified Bacteria	2|Bacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6158419_4	1121904.ARBP01000032_gene2008	1.038e-09	70.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,47NDQ@768503|Cytophagia	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
LZS2_k127_6191708_22	717231.Flexsi_1347	1.615e-10	65.0	COG1343@1|root,COG1343@2|Bacteria,2GGK7@200930|Deferribacteres	2|Bacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
LZS2_k127_6191708_2	304371.MCP_1385	1.397e-227	713.0	COG0557@1|root,arCOG04686@2157|Archaea,2XT2E@28890|Euryarchaeota,2NA9N@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM ribonuclease II	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
LZS2_k127_6191708_20	96561.Dole_2882	8.344e-12	67.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2MJ5F@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
LZS2_k127_6191708_5	933262.AXAM01000009_gene1490	1.084e-137	450.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,42NHH@68525|delta/epsilon subdivisions,2WJ6M@28221|Deltaproteobacteria,2MIS1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	qmoA	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,NAD_binding_8,Pyr_redox_2
LZS2_k127_6191708_1	387631.Asulf_02109	1.766e-257	814.0	COG1148@1|root,COG1908@1|root,arCOG02235@2157|Archaea,arCOG02476@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
LZS2_k127_6191708_7	555779.Dthio_PD1623	3.345e-81	287.0	COG1150@1|root,COG1150@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2M85U@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
LZS2_k127_6191708_21	880072.Desac_2728	1.101e-11	72.0	arCOG10385@1|root,32SEM@2|Bacteria,1N1IG@1224|Proteobacteria,42TMW@68525|delta/epsilon subdivisions,2WQBW@28221|Deltaproteobacteria,2MRWB@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6191708_10	156889.Mmc1_1708	3.778e-68	240.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2TTE2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
LZS2_k127_6191708_9	224325.AF_0500	2.128e-71	259.0	COG5557@1|root,arCOG02025@2157|Archaea,2XWFI@28890|Euryarchaeota,246T1@183980|Archaeoglobi	183980|Archaeoglobi	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
LZS2_k127_6191708_14	701347.Entcl_1498	1.413e-37	161.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,1T26Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Member of the two-component regulatory system AtoS AtoC. In the presence of acetoacetate, AtoS AtoC stimulates the expression of the atoDAEB operon, leading to short chain fatty acid catabolism and activation of the poly-(R)-3-hydroxybutyrate (cPHB) biosynthetic pathway. Also induces the operon in response to spermidine. Involved in the regulation of motility and chemotaxis, via transcriptional induction of the flagellar regulon. AtoS is a membrane-associated kinase that phosphorylates and activates AtoC in response to environmental signals	atoS	GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS
LZS2_k127_6191708_18	1265505.ATUG01000003_gene517	9.825e-26	111.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria,2MN9A@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_6191708_19	1550073.JROH01000037_gene2566	6.134e-18	96.0	COG3746@1|root,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria,2U14X@28211|Alphaproteobacteria,2K3MH@204457|Sphingomonadales	204457|Sphingomonadales	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
LZS2_k127_6191708_6	886293.Sinac_3879	8.851e-121	401.0	COG0381@1|root,COG0381@2|Bacteria,2IWR6@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS2_k127_6191708_3	1366050.N234_18155	8.244e-158	512.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,2VMZI@28216|Betaproteobacteria,1K5UP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
LZS2_k127_6191708_16	1159870.KB907784_gene871	2.331e-31	137.0	COG4801@1|root,COG4801@2|Bacteria,1NCJ7@1224|Proteobacteria,2VX0J@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS2_k127_6191708_17	861299.J421_4217	8.617e-29	128.0	2E80J@1|root,317EG@2|Bacteria,1ZUYZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6191708_23	1366050.N234_18170	7.272e-09	66.0	2E6HX@1|root,33155@2|Bacteria,1N8IS@1224|Proteobacteria,2VX0B@28216|Betaproteobacteria,1K9EG@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6191708_0	655815.ZPR_2342	1.415e-287	900.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1HZ57@117743|Flavobacteriia	976|Bacteroidetes	E	oligopeptidase that cleaves peptide bonds following arginine and lysine residues	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS2_k127_6191708_15	945713.IALB_2665	1.383e-33	140.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
LZS2_k127_6191708_24	472759.Nhal_2951	1.533e-06	53.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,1SHCR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Transmembrane anti-sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS2_k127_6191708_12	240015.ACP_1219	4.054e-46	173.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_6191708_4	1047013.AQSP01000139_gene2392	1.785e-148	482.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS2_k127_6191708_13	1487921.DP68_09770	1.547e-42	164.0	COG4758@1|root,COG4758@2|Bacteria,1VE20@1239|Firmicutes,24J2R@186801|Clostridia,36JE0@31979|Clostridiaceae	186801|Clostridia	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
LZS2_k127_6191708_8	880073.Calab_1274	4.032e-78	268.0	COG2220@1|root,COG2220@2|Bacteria,2NPQC@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the UPF0173 family	ytkL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
LZS2_k127_6191708_11	595460.RRSWK_04881	1.63e-52	202.0	COG0515@1|root,COG0515@2|Bacteria	595460.RRSWK_04881|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6216641_1	1170562.Cal6303_3093	4.667e-06	59.0	COG1749@1|root,COG1749@2|Bacteria,1G2ZW@1117|Cyanobacteria	1117|Cyanobacteria	N	Ig domain protein group 1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,DUF4082
LZS2_k127_6216641_0	1321778.HMPREF1982_00035	4.696e-146	474.0	COG2511@1|root,COG2511@2|Bacteria,1UPG0@1239|Firmicutes,25HFT@186801|Clostridia	186801|Clostridia	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
LZS2_k127_6248452_8	1128421.JAGA01000003_gene3011	6.546e-49	178.0	COG1249@1|root,COG1249@2|Bacteria,2NNTI@2323|unclassified Bacteria	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS2_k127_6248452_4	861299.J421_3598	2.203e-92	315.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
LZS2_k127_6248452_2	234267.Acid_0352	7.459e-119	390.0	COG1071@1|root,COG1071@2|Bacteria,3Y4M3@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
LZS2_k127_6248452_0	234267.Acid_0353	1.782e-147	473.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS2_k127_6248452_1	1121920.AUAU01000004_gene789	4.357e-122	406.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS2_k127_6248452_5	671143.DAMO_1594	1.356e-62	228.0	COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
LZS2_k127_6248452_3	1121920.AUAU01000012_gene2645	1.731e-100	336.0	COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_6248452_7	1347392.CCEZ01000043_gene560	2.442e-55	200.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,36I3Z@31979|Clostridiaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS2_k127_6248452_6	1242864.D187_003382	8.455e-56	207.0	COG1468@1|root,COG1468@2|Bacteria	2|Bacteria	L	DNA catabolic process, exonucleolytic	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779,PDDEXK_1
LZS2_k127_6248907_2	1047013.AQSP01000045_gene108	4.871e-96	319.0	COG1748@1|root,COG1748@2|Bacteria,2NNZ1@2323|unclassified Bacteria	2|Bacteria	E	Saccharopine dehydrogenase C-terminal domain	lys2	-	1.5.1.10	ko:K00293	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R02315	RC00215,RC00225	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
LZS2_k127_6248907_0	1047013.AQSP01000045_gene109	2.852e-143	467.0	COG0686@1|root,COG0686@2|Bacteria,2NNTE@2323|unclassified Bacteria	2|Bacteria	E	Alanine dehydrogenase/PNT, N-terminal domain	sdh	-	1.5.1.7,1.5.1.8,1.5.1.9	ko:K00290,ko:K14157	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715,R00716,R02313	RC00215,RC00217,RC00225,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
LZS2_k127_6248907_3	945713.IALB_0145	2.655e-20	108.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
LZS2_k127_6248907_4	10029.XP_007632591.1	6.461e-07	64.0	KOG3637@1|root,KOG3637@2759|Eukaryota,38CFX@33154|Opisthokonta,3B96W@33208|Metazoa,3CSVN@33213|Bilateria,485YR@7711|Chordata,48US3@7742|Vertebrata,3J5TG@40674|Mammalia,35IRF@314146|Euarchontoglires,4PYHS@9989|Rodentia	33208|Metazoa	W	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	ITGA4	GO:0000003,GO:0000902,GO:0000904,GO:0001555,GO:0001667,GO:0001700,GO:0001701,GO:0001704,GO:0001706,GO:0001775,GO:0001890,GO:0001892,GO:0001936,GO:0001938,GO:0001968,GO:0001974,GO:0002009,GO:0002011,GO:0002164,GO:0002376,GO:0002520,GO:0002521,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002691,GO:0002693,GO:0003006,GO:0003008,GO:0003344,GO:0003366,GO:0003674,GO:0003823,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0005911,GO:0005912,GO:0005924,GO:0005925,GO:0006810,GO:0006897,GO:0006898,GO:0006909,GO:0006928,GO:0006935,GO:0006950,GO:0007154,GO:0007155,GO:0007157,GO:0007159,GO:0007160,GO:0007165,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007369,GO:0007391,GO:0007399,GO:0007409,GO:0007411,GO:0007424,GO:0007431,GO:0007492,GO:0007494,GO:0007507,GO:0007508,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007614,GO:0007635,GO:0008104,GO:0008150,GO:0008284,GO:0008305,GO:0008306,GO:0008355,GO:0008582,GO:0009605,GO:0009611,GO:0009636,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009888,GO:0009897,GO:0009925,GO:0009986,GO:0009987,GO:0009994,GO:0010033,GO:0010941,GO:0010942,GO:0015026,GO:0016020,GO:0016021,GO:0016043,GO:0016049,GO:0016192,GO:0016323,GO:0016324,GO:0016331,GO:0016339,GO:0016340,GO:0016477,GO:0019953,GO:0022008,GO:0022407,GO:0022409,GO:0022412,GO:0022414,GO:0022610,GO:0023052,GO:0030030,GO:0030054,GO:0030055,GO:0030097,GO:0030098,GO:0030154,GO:0030155,GO:0030182,GO:0030183,GO:0030198,GO:0030334,GO:0030335,GO:0030336,GO:0030534,GO:0031175,GO:0031224,GO:0031226,GO:0031589,GO:0031982,GO:0032091,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033627,GO:0034113,GO:0034446,GO:0034613,GO:0034669,GO:0035001,GO:0035272,GO:0035295,GO:0035987,GO:0038023,GO:0040007,GO:0040008,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0042048,GO:0042060,GO:0042113,GO:0042127,GO:0042221,GO:0042330,GO:0042493,GO:0042981,GO:0043009,GO:0043062,GO:0043065,GO:0043067,GO:0043068,GO:0043113,GO:0043226,GO:0043227,GO:0043230,GO:0043235,GO:0043277,GO:0043393,GO:0043496,GO:0044087,GO:0044092,GO:0044421,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044703,GO:0045123,GO:0045177,GO:0045178,GO:0045321,GO:0045471,GO:0045785,GO:0045886,GO:0045926,GO:0046649,GO:0046677,GO:0046982,GO:0046983,GO:0048149,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048565,GO:0048568,GO:0048569,GO:0048583,GO:0048588,GO:0048589,GO:0048598,GO:0048599,GO:0048608,GO:0048609,GO:0048638,GO:0048640,GO:0048646,GO:0048666,GO:0048667,GO:0048699,GO:0048729,GO:0048731,GO:0048732,GO:0048771,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050776,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050839,GO:0050877,GO:0050890,GO:0050896,GO:0050900,GO:0050901,GO:0050904,GO:0051093,GO:0051098,GO:0051100,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051270,GO:0051271,GO:0051272,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0051668,GO:0051674,GO:0051704,GO:0051716,GO:0051960,GO:0051961,GO:0051963,GO:0051964,GO:0055123,GO:0060039,GO:0060089,GO:0060322,GO:0060324,GO:0060429,GO:0060485,GO:0060541,GO:0060560,GO:0060669,GO:0060710,GO:0060711,GO:0060713,GO:0061032,GO:0061458,GO:0061564,GO:0061756,GO:0065007,GO:0065008,GO:0065009,GO:0070062,GO:0070161,GO:0070727,GO:0071840,GO:0071944,GO:0072359,GO:0072583,GO:0072657,GO:0072676,GO:0072678,GO:0090074,GO:0097305,GO:0097485,GO:0098552,GO:0098590,GO:0098609,GO:0098636,GO:0098657,GO:0098742,GO:0098796,GO:0098797,GO:0098802,GO:0120036,GO:0120039,GO:1901700,GO:1903037,GO:1903039,GO:1903236,GO:1903238,GO:1903561,GO:1904035,GO:1904037,GO:1904396,GO:1904397,GO:1904994,GO:1904996,GO:1905562,GO:1905564,GO:1905809,GO:1990405,GO:1990771,GO:2000026,GO:2000145,GO:2000146,GO:2000147,GO:2000351,GO:2000353,GO:2000401,GO:2000403,GO:2000404,GO:2000406	-	ko:K06483,ko:K06484,ko:K06487,ko:K06584,ko:K06585	ko04145,ko04151,ko04510,ko04512,ko04514,ko04640,ko04670,ko04672,ko04810,ko04919,ko05100,ko05131,ko05133,ko05140,ko05165,ko05200,ko05205,ko05206,ko05222,ko05410,ko05412,ko05414,ko05418,map04145,map04151,map04510,map04512,map04514,map04640,map04670,map04672,map04810,map04919,map05100,map05131,map05133,map05140,map05165,map05200,map05205,map05206,map05222,map05410,map05412,map05414,map05418	-	-	-	ko00000,ko00001,ko04090,ko04131,ko04147,ko04516	-	-	-	FG-GAP,Integrin_alpha2
LZS2_k127_6248907_1	382464.ABSI01000016_gene740	6.759e-108	392.0	COG2982@1|root,COG4932@1|root,COG2982@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	AsmA_2,CHU_C,Cna_B,DUF11,Invasin_D3,PPC,Peptidase_M10_C,Reprolysin_4,SprB,VCBS
LZS2_k127_6248907_5	8090.ENSORLP00000002048	0.0001202	56.0	KOG3637@1|root,KOG3637@2759|Eukaryota,39SNZ@33154|Opisthokonta,3BCVJ@33208|Metazoa,3CYNU@33213|Bilateria,485VM@7711|Chordata,48ZZI@7742|Vertebrata,49ZJ9@7898|Actinopterygii	33208|Metazoa	W	Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1	ITGAL	GO:0001772,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002285,GO:0002286,GO:0002291,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002682,GO:0002684,GO:0002694,GO:0002696,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0005911,GO:0006810,GO:0006887,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007154,GO:0007155,GO:0007157,GO:0007159,GO:0007160,GO:0007165,GO:0007166,GO:0008104,GO:0008150,GO:0008283,GO:0008284,GO:0008305,GO:0009897,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0012505,GO:0012506,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016477,GO:0022407,GO:0022409,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0030054,GO:0030141,GO:0030155,GO:0030198,GO:0030369,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031589,GO:0031982,GO:0032940,GO:0032943,GO:0032944,GO:0032946,GO:0032991,GO:0033036,GO:0034613,GO:0034687,GO:0035579,GO:0036230,GO:0038023,GO:0040011,GO:0042098,GO:0042102,GO:0042110,GO:0042119,GO:0042127,GO:0042129,GO:0042581,GO:0043062,GO:0043113,GO:0043226,GO:0043227,GO:0043229,GO:0043235,GO:0043299,GO:0043312,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045321,GO:0045785,GO:0046649,GO:0046651,GO:0046903,GO:0046982,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048870,GO:0050670,GO:0050671,GO:0050776,GO:0050789,GO:0050794,GO:0050798,GO:0050839,GO:0050848,GO:0050850,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0050900,GO:0051179,GO:0051234,GO:0051249,GO:0051251,GO:0051641,GO:0051668,GO:0051674,GO:0051716,GO:0060089,GO:0065007,GO:0070661,GO:0070663,GO:0070665,GO:0070727,GO:0071840,GO:0071944,GO:0072657,GO:0097708,GO:0098552,GO:0098588,GO:0098609,GO:0098636,GO:0098742,GO:0098796,GO:0098797,GO:0098802,GO:0098805,GO:0099503,GO:1902531,GO:1902533,GO:1903037,GO:1903039	-	ko:K05718	ko04015,ko04514,ko04650,ko04670,ko04810,ko05144,ko05150,ko05166,ko05169,ko05323,ko05416,map04015,map04514,map04650,map04670,map04810,map05144,map05150,map05166,map05169,map05323,map05416	-	-	-	ko00000,ko00001,ko04090,ko04147,ko04516	-	-	-	FG-GAP,Integrin_alpha,Integrin_alpha2,VWA
LZS2_k127_6271809_7	1196028.ALEF01000008_gene3273	1.782e-34	141.0	COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,4HAA2@91061|Bacilli,4C5M3@84406|Virgibacillus	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
LZS2_k127_6271809_1	526222.Desal_1559	5.602e-132	432.0	COG0160@1|root,COG0160@2|Bacteria,1QY1E@1224|Proteobacteria,43C8R@68525|delta/epsilon subdivisions,2X88X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_6271809_3	1254432.SCE1572_07235	1.113e-57	215.0	COG2021@1|root,COG2021@2|Bacteria,1PG00@1224|Proteobacteria,439DK@68525|delta/epsilon subdivisions,2X4NG@28221|Deltaproteobacteria,2YZAN@29|Myxococcales	28221|Deltaproteobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS2_k127_6271809_2	1379698.RBG1_1C00001G0936	3.695e-88	295.0	COG1335@1|root,COG1335@2|Bacteria,2NRGH@2323|unclassified Bacteria	2|Bacteria	Q	Isochorismatase family	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
LZS2_k127_6271809_9	555088.DealDRAFT_0538	4.093e-10	63.0	28WBK@1|root,2ZIC0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6271809_10	1157490.EL26_02225	4.176e-09	60.0	COG4430@1|root,COG4430@2|Bacteria,1VJJF@1239|Firmicutes,4IRZ2@91061|Bacilli	91061|Bacilli	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
LZS2_k127_6271809_4	553218.CAMRE0001_2504	8.375e-53	194.0	2AHNX@1|root,3180Y@2|Bacteria,1PZMA@1224|Proteobacteria,42QU6@68525|delta/epsilon subdivisions,2YNVR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
LZS2_k127_6271809_6	313606.M23134_02207	4.264e-39	149.0	COG0662@1|root,COG0662@2|Bacteria,4NQAT@976|Bacteroidetes	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS2_k127_6271809_8	1205908.AKXW01000023_gene799	4.216e-13	79.0	COG3650@1|root,COG3650@2|Bacteria,1RIIM@1224|Proteobacteria,1S8NS@1236|Gammaproteobacteria,1XSAK@135623|Vibrionales	135623|Vibrionales	S	response to hydrogen peroxide	VP2977	-	-	ko:K08985	-	-	-	-	ko00000	-	-	-	-
LZS2_k127_6271809_0	247490.KSU1_C0538	7.169e-136	438.0	COG1741@1|root,COG1741@2|Bacteria,2IXVU@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
LZS2_k127_6271809_11	314271.RB2654_15886	5.031e-09	60.0	2EFVW@1|root,339N3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6271809_5	1210884.HG799467_gene13232	1.075e-48	177.0	COG2095@1|root,COG2095@2|Bacteria,2J0YY@203682|Planctomycetes	203682|Planctomycetes	U	MarC family integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	MarC
LZS2_k127_6290752_0	459349.CLOAM0177	1.269e-172	553.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
LZS2_k127_6290752_1	1131269.AQVV01000004_gene638	9.488e-151	487.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS2_k127_6365377_4	1117108.PAALTS15_13192	1.67e-75	262.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HB0J@91061|Bacilli,26QCJ@186822|Paenibacillaceae	91061|Bacilli	I	acyl-CoA dehydrogenase	fadE	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_6365377_6	945713.IALB_1544	1.126e-49	192.0	COG3240@1|root,COG3240@2|Bacteria	2|Bacteria	I	lipase activity	-	-	-	ko:K15349	ko05132,map05132	-	-	-	ko00000,ko00001	-	-	-	Lipase_GDSL,Lipase_GDSL_2
LZS2_k127_6365377_5	1191523.MROS_2563	2.951e-71	258.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
LZS2_k127_6365377_1	1379270.AUXF01000004_gene3094	2.121e-175	569.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
LZS2_k127_6365377_0	1047013.AQSP01000101_gene607	0.0	1124.0	COG1882@1|root,COG1882@2|Bacteria,2NQDK@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate formate lyase-like	pflD	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
LZS2_k127_6365377_3	1304888.ATWF01000001_gene994	5.976e-79	272.0	COG1180@1|root,COG1180@2|Bacteria,2GFJN@200930|Deferribacteres	200930|Deferribacteres	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS2_k127_6365377_11	264730.PSPPH_0202	5.272e-30	123.0	COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria,1Z80B@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
LZS2_k127_6365377_9	926550.CLDAP_15510	8.18e-42	167.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Thiamin pyrophosphokinase, catalytic region	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
LZS2_k127_6365377_10	1423321.AS29_03315	1.404e-32	135.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,4HG4G@91061|Bacilli,1ZEB4@1386|Bacillus	91061|Bacilli	G	2-dehydro-3-deoxy-phosphogluconate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
LZS2_k127_6365377_8	439235.Dalk_0807	3.139e-44	166.0	2A42S@1|root,30SMP@2|Bacteria,1RFZA@1224|Proteobacteria,42S6K@68525|delta/epsilon subdivisions,2WNVV@28221|Deltaproteobacteria,2MK2E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Nickel-containing superoxide dismutase	-	-	1.15.1.1	ko:K00518	-	-	-	-	ko00000,ko01000	-	-	-	Sod_Ni
LZS2_k127_6365377_2	335543.Sfum_2844	2.16e-125	409.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2WKFT@28221|Deltaproteobacteria,2MQ5J@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
LZS2_k127_6365377_12	390874.Tpet_1655	3.587e-19	102.0	COG0569@1|root,COG0569@2|Bacteria,2GCXD@200918|Thermotogae	200918|Thermotogae	C	PFAM TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	iLJ478.TM1088	TrkA_C,TrkA_N
LZS2_k127_6365377_7	926692.AZYG01000094_gene1934	1.156e-46	190.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia	186801|Clostridia	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,Usp
LZS2_k127_6381094_12	867845.KI911784_gene468	2.172e-17	89.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,SpoIIE
LZS2_k127_6381094_7	1379698.RBG1_1C00001G0632	2.069e-26	111.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS2_k127_6381094_4	401526.TcarDRAFT_2095	4.687e-76	266.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4H2QQ@909932|Negativicutes	909932|Negativicutes	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS2_k127_6381094_8	1232410.KI421420_gene3159	5.272e-25	110.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,43UXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
LZS2_k127_6381094_11	1379698.RBG1_1C00001G0104	3.596e-20	94.0	COG1734@1|root,COG1734@2|Bacteria,2NPX2@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulator, TraR DksA family	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS2_k127_6381094_0	555079.Toce_1642	0.0	1100.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,42F4D@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
LZS2_k127_6381094_2	243090.RB6588	7.567e-95	319.0	COG0005@1|root,COG0005@2|Bacteria,2IX9R@203682|Planctomycetes	203682|Planctomycetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS2_k127_6381094_14	1123366.TH3_04579	3.359e-11	67.0	COG1872@1|root,COG1872@2|Bacteria,1N6V2@1224|Proteobacteria,2UF67@28211|Alphaproteobacteria,2JUA1@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
LZS2_k127_6381094_10	290397.Adeh_1311	1.62e-21	106.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WS27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
LZS2_k127_6381094_13	795359.TOPB45_1268	1.168e-14	76.0	COG0762@1|root,COG0762@2|Bacteria,2GHYF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
LZS2_k127_6381094_6	370438.PTH_1828	3.515e-55	203.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,261IH@186807|Peptococcaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
LZS2_k127_6381094_9	247490.KSU1_C0730	1.939e-22	113.0	COG2234@1|root,COG3291@1|root,COG3420@1|root,COG4409@1|root,COG5184@1|root,COG5276@1|root,COG2234@2|Bacteria,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4409@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	iap	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6	ko:K01179,ko:K03929,ko:K09612,ko:K12287,ko:K19701,ko:K19702	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko02044	-	CE10,GH5,GH9	-	Beta_helix,Peptidase_M28
LZS2_k127_6381094_5	1232410.KI421421_gene3398	9.347e-65	228.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,43SH1@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PhoU domain	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
LZS2_k127_6381094_1	1232410.KI421421_gene3404	1.811e-189	609.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43SD2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
LZS2_k127_6381094_3	880072.Desac_2636	1.357e-94	315.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_6389620_0	1379698.RBG1_1C00001G0150	1.995e-97	322.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS2_k127_6389620_6	373903.Hore_17830	2.137e-22	103.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,3WATA@53433|Halanaerobiales	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
LZS2_k127_6389620_4	1379698.RBG1_1C00001G0148	1.183e-27	119.0	COG0711@1|root,COG0711@2|Bacteria,2NQ34@2323|unclassified Bacteria	2|Bacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
LZS2_k127_6389620_5	1379698.RBG1_1C00001G0147	8.492e-23	100.0	COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria	2|Bacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
LZS2_k127_6389620_1	1379698.RBG1_1C00001G0146	2.84e-83	285.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
LZS2_k127_6389620_7	1379698.RBG1_1C00001G0145	1.414e-10	68.0	2EPKR@1|root,33H7C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6389620_8	1437425.CSEC_0646	1.797e-10	64.0	2EQQP@1|root,33IAK@2|Bacteria,2JGJU@204428|Chlamydiae	204428|Chlamydiae	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
LZS2_k127_6389620_2	671143.DAMO_0259	1.451e-72	255.0	COG1091@1|root,COG1091@2|Bacteria,2NPG4@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS2_k127_6389620_3	1041930.Mtc_0198	1.57e-55	202.0	COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
LZS2_k127_6412801_1	289376.THEYE_A1035	8.117e-55	199.0	COG0483@1|root,COG0483@2|Bacteria,3J0I4@40117|Nitrospirae	40117|Nitrospirae	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
LZS2_k127_6412801_3	1034769.KB910518_gene440	4.181e-43	169.0	COG0583@1|root,COG0583@2|Bacteria,1V0M9@1239|Firmicutes,4HEKQ@91061|Bacilli,26UAN@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	rbcR3	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS2_k127_6412801_0	234267.Acid_1254	7.677e-206	647.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria	57723|Acidobacteria	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
LZS2_k127_6412801_2	335543.Sfum_0970	3.038e-45	177.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,43BSH@68525|delta/epsilon subdivisions,2X73A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
LZS2_k127_6449101_0	1519464.HY22_04560	2.005e-31	139.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
LZS2_k127_6476107_1	309801.trd_1299	1.922e-44	177.0	COG0438@1|root,COG0438@2|Bacteria,2G8W3@200795|Chloroflexi,27Y3X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
LZS2_k127_6476107_0	1122176.KB903551_gene4232	9.214e-54	198.0	COG0463@1|root,COG0463@2|Bacteria,4NGYU@976|Bacteroidetes,1IU82@117747|Sphingobacteriia	976|Bacteroidetes	M	involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS2_k127_6476107_3	404380.Gbem_0849	1.371e-24	116.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS2_k127_6476107_2	1191523.MROS_2494	8.226e-37	155.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
LZS2_k127_6476107_4	290397.Adeh_2610	5.004e-19	89.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
LZS2_k127_659238_3	518766.Rmar_0403	1.748e-53	196.0	COG0042@1|root,COG0042@2|Bacteria,4NEN4@976|Bacteroidetes,1FJ2S@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Dihydrouridine synthase (Dus)	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
LZS2_k127_659238_2	871963.Desdi_2004	2.098e-70	248.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,260TX@186807|Peptococcaceae	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
LZS2_k127_659238_1	926569.ANT_23230	6.472e-77	271.0	COG1641@1|root,COG1641@2|Bacteria,2G5MP@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
LZS2_k127_659238_5	269797.Mbar_A3643	2.718e-09	68.0	COG0457@1|root,arCOG05195@1|root,arCOG03038@2157|Archaea,arCOG05195@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAF9@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
LZS2_k127_659238_4	742722.HMPREF9463_01013	1.791e-48	194.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4CUE1@84998|Coriobacteriia	84998|Coriobacteriia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF87
LZS2_k127_659238_0	518766.Rmar_1183	1.122e-222	720.0	COG0823@1|root,COG1262@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FIPY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EU	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PD40,Peptidase_S9
LZS2_k127_6636101_0	596151.DesfrDRAFT_0992	1.424e-57	216.0	COG4961@1|root,COG4961@2|Bacteria,1NIG7@1224|Proteobacteria,42X7K@68525|delta/epsilon subdivisions,2WSKV@28221|Deltaproteobacteria,2M9N1@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
LZS2_k127_6636101_1	1449076.JOOE01000002_gene805	2.282e-53	203.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,2K2YM@204457|Sphingomonadales	204457|Sphingomonadales	U	Pilus formation protein N terminal region	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
LZS2_k127_6636101_3	234267.Acid_1409	1.37e-33	141.0	COG3745@1|root,COG3745@2|Bacteria,3Y4HR@57723|Acidobacteria	57723|Acidobacteria	U	PFAM SAF domain	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
LZS2_k127_6636101_7	1305836.AXVE01000001_gene2811	2.262e-10	67.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,4HNWE@91061|Bacilli	91061|Bacilli	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS2_k127_6636101_6	555088.DealDRAFT_0655	5.505e-11	70.0	COG4960@1|root,COG4960@2|Bacteria,1UPNE@1239|Firmicutes,24T5Y@186801|Clostridia	186801|Clostridia	OU	PFAM peptidase A24A, prepilin type IV	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
LZS2_k127_6636101_8	1120998.AUFC01000036_gene1283	6.95e-05	46.0	2EHTG@1|root,33BJ4@2|Bacteria	2|Bacteria	S	Flp Fap pilin component	-	-	-	-	-	-	-	-	-	-	-	-	Flp_Fap
LZS2_k127_6636101_5	338966.Ppro_2697	2.985e-15	85.0	COG1430@1|root,COG1430@2|Bacteria,1N7U4@1224|Proteobacteria,42VKG@68525|delta/epsilon subdivisions,2WSD0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
LZS2_k127_6636101_2	1232410.KI421416_gene2655	1.789e-51	192.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria,43U05@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6636101_4	933262.AXAM01000016_gene190	8.944e-30	120.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2MI4N@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_6646027_3	1122179.KB890414_gene1882	9.686e-19	93.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
LZS2_k127_6646027_6	1313421.JHBV01000049_gene63	8.155e-08	64.0	COG1262@1|root,COG1262@2|Bacteria,4NW0B@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6646027_5	706587.Desti_1616	9.999e-16	85.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42V72@68525|delta/epsilon subdivisions,2WRHE@28221|Deltaproteobacteria,2MSA6@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_6646027_2	1163409.UUA_01479	8.03e-50	191.0	COG4585@1|root,COG4585@2|Bacteria,1R9XM@1224|Proteobacteria,1S54U@1236|Gammaproteobacteria,1X997@135614|Xanthomonadales	135614|Xanthomonadales	T	STAS-like domain of unknown function (DUF4325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4325
LZS2_k127_6646027_1	86416.Clopa_4793	3.65e-61	219.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,36EH8@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_6646027_0	344747.PM8797T_02024	1.499e-93	321.0	COG0577@1|root,COG0577@2|Bacteria,2J25K@203682|Planctomycetes	2|Bacteria	V	COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_6646027_4	1347393.HG726025_gene2686	3.374e-16	85.0	2F4XF@1|root,30MY7@2|Bacteria,4PAMZ@976|Bacteroidetes,2FXAS@200643|Bacteroidia,4AT18@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6648755_2	1172179.AUKV01000034_gene7064	1.99e-23	117.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria	201174|Actinobacteria	M	PFAM peptidase M6, immune inhibitor A	ina	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
LZS2_k127_6648755_3	880073.Calab_0921	6.003e-19	102.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS2_k127_6648755_0	247490.KSU1_C1550	5.663e-52	193.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	ideR	-	-	ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
LZS2_k127_6648755_1	247490.KSU1_C1548	1.653e-40	153.0	COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes	203682|Planctomycetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
LZS2_k127_6653599_2	706587.Desti_2766	9.363e-84	285.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MRB2@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS2_k127_6653599_3	404380.Gbem_0801	9.437e-56	215.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
LZS2_k127_6653599_0	858215.Thexy_0730	8.418e-170	560.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,42EUR@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS2_k127_6653599_1	1379698.RBG1_1C00001G0340	6.374e-168	565.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
LZS2_k127_6653599_4	1449065.JMLL01000010_gene1130	7.455e-09	68.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,43HWN@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
LZS2_k127_6657268_7	760568.Desku_2253	1.806e-09	60.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,261T9@186807|Peptococcaceae	186801|Clostridia	S	PFAM Appr-1-p processing	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
LZS2_k127_6657268_5	926569.ANT_29310	3.902e-29	129.0	299R9@1|root,2ZWTI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6657268_4	1304872.JAGC01000009_gene1266	1.4e-37	150.0	COG1611@1|root,COG1611@2|Bacteria,1RJ91@1224|Proteobacteria,42TR7@68525|delta/epsilon subdivisions,2WQUE@28221|Deltaproteobacteria,2MC13@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DNA_processg_A,Lysine_decarbox
LZS2_k127_6657268_2	484019.THA_203	3.415e-71	249.0	COG1351@1|root,COG1351@2|Bacteria,2GC26@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
LZS2_k127_6657268_0	868131.MSWAN_0651	3.317e-95	324.0	COG2006@1|root,arCOG02447@2157|Archaea,2XW1U@28890|Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S ferredoxin iron-sulfur binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_7
LZS2_k127_6657268_6	1123373.ATXI01000002_gene721	2.141e-21	103.0	COG0664@1|root,COG0664@2|Bacteria,2GHZ5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS2_k127_6657268_1	880073.Calab_1912	1.698e-77	268.0	COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS2_k127_6657268_3	290397.Adeh_4094	3.3e-53	189.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2Z0PZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
LZS2_k127_6679453_13	1123274.KB899413_gene789	3.11e-23	101.0	COG2896@1|root,COG2896@2|Bacteria,2J7IB@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
LZS2_k127_6679453_10	573413.Spirs_1629	3.109e-45	170.0	COG0315@1|root,COG0315@2|Bacteria,2J81J@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
LZS2_k127_6679453_5	1408473.JHXO01000010_gene3615	3.274e-107	356.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,4PNHR@976|Bacteroidetes	976|Bacteroidetes	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoaC
LZS2_k127_6679453_7	1347369.CCAD010000080_gene3144	5.368e-63	229.0	COG1073@1|root,COG1073@2|Bacteria,1TPW7@1239|Firmicutes,4HN9I@91061|Bacilli,1ZR05@1386|Bacillus	91061|Bacilli	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S15
LZS2_k127_6679453_16	83406.HDN1F_21550	1.469e-06	53.0	COG5276@1|root,COG5276@2|Bacteria,1R46A@1224|Proteobacteria,1RY7V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD
LZS2_k127_6679453_3	502025.Hoch_4149	4.392e-192	616.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,42MG1@68525|delta/epsilon subdivisions,2WKHE@28221|Deltaproteobacteria,2YYFS@29|Myxococcales	28221|Deltaproteobacteria	E	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
LZS2_k127_6679453_6	706587.Desti_0126	6.729e-72	244.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WNIG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
LZS2_k127_6679453_14	706587.Desti_0703	4.723e-20	91.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WNIG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
LZS2_k127_6679453_12	886293.Sinac_6279	2.397e-30	124.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
LZS2_k127_6679453_9	861299.J421_1461	2.176e-46	187.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
LZS2_k127_6679453_15	391603.FBALC1_08928	3.698e-15	89.0	COG0457@1|root,COG1228@1|root,COG0457@2|Bacteria,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS2_k127_6679453_11	5059.CADAFLAP00013384	2.18e-35	155.0	COG0666@1|root,KOG0504@2759|Eukaryota,39YNX@33154|Opisthokonta	33154|Opisthokonta	B	retrograde transport, endosome to plasma membrane	-	-	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank,Ank_2,Ank_4,NACHT,NACHT_N
LZS2_k127_6679453_8	1047013.AQSP01000051_gene2576	5.382e-62	237.0	COG2220@1|root,COG2220@2|Bacteria,2NRBH@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
LZS2_k127_6679453_17	1123514.KB905900_gene2188	3.349e-06	51.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_6679453_2	926550.CLDAP_19500	6.371e-213	707.0	COG0584@1|root,COG0823@1|root,COG3210@1|root,COG4886@1|root,COG0584@2|Bacteria,COG0823@2|Bacteria,COG3210@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	3.1.4.46	ko:K01126,ko:K21449	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000,ko02000	1.B.40.2	-	-	GDPD_2
LZS2_k127_6679453_1	1191523.MROS_2024	2.351e-219	687.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_6679453_0	1499967.BAYZ01000119_gene3216	3.765e-296	941.0	COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
LZS2_k127_6679453_4	1123274.KB899414_gene3603	8.621e-129	430.0	COG0574@1|root,COG0784@1|root,COG2197@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria,COG2197@2|Bacteria	2|Bacteria	K	response regulator	ppsA	-	2.7.9.2	ko:K01007,ko:K07699	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02020,ko02024,map00620,map00680,map00720,map01100,map01120,map01200,map02020,map02024	M00173,M00374,M00485	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	PPDK_N,Response_reg,SpoIIE
LZS2_k127_6691905_0	926550.CLDAP_17040	4.503e-175	578.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
LZS2_k127_6691905_3	880073.Calab_0913	2.522e-18	100.0	COG1523@1|root,COG1523@2|Bacteria	2|Bacteria	G	belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
LZS2_k127_6691905_2	1125863.JAFN01000001_gene1391	5.933e-91	314.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1PEPK@1224|Proteobacteria,42NJ8@68525|delta/epsilon subdivisions,2WM57@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Peptidase_M1
LZS2_k127_6691905_1	472759.Nhal_2872	2.998e-140	471.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1SYTD@1236|Gammaproteobacteria,1X2IM@135613|Chromatiales	135613|Chromatiales	EO	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M1,Peptidase_M28
LZS2_k127_6710411_2	644282.Deba_2293	1.663e-24	106.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS2_k127_6710411_5	391625.PPSIR1_29905	1.609e-07	63.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria,2YUQA@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
LZS2_k127_6710411_1	1379698.RBG1_1C00001G0518	3.637e-40	159.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS2_k127_6710411_7	1379698.RBG1_1C00001G0607	4.18e-05	49.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS2_k127_6710411_3	404589.Anae109_3641	1.772e-15	83.0	2E3NC@1|root,32YKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6710411_4	1296990.H845_3056	8.513e-11	73.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TSFP@28211|Alphaproteobacteria,2JQJS@204441|Rhodospirillales	204441|Rhodospirillales	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS2_k127_6710411_0	1128421.JAGA01000003_gene2811	2.253e-154	496.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS2_k127_6710411_6	765914.ThisiDRAFT_0804	2.164e-05	57.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1WVXZ@135613|Chromatiales	135613|Chromatiales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
LZS2_k127_6715493_11	215803.DB30_7346	2.777e-24	117.0	COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria,2Z3FM@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
LZS2_k127_6715493_5	1267535.KB906767_gene4838	5.833e-80	291.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
LZS2_k127_6715493_7	96561.Dole_0580	1.511e-54	197.0	COG5561@1|root,COG5561@2|Bacteria,1RH81@1224|Proteobacteria,42SY4@68525|delta/epsilon subdivisions,2WPAG@28221|Deltaproteobacteria,2MK3G@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
LZS2_k127_6715493_2	177437.HRM2_08060	1.172e-154	497.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WJKF@28221|Deltaproteobacteria,2MJD9@213118|Desulfobacterales	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS2_k127_6715493_16	1047013.AQSP01000114_gene686	1.185e-09	64.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
LZS2_k127_6715493_3	1123288.SOV_1c07130	2.948e-127	419.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,4H2G7@909932|Negativicutes	909932|Negativicutes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
LZS2_k127_6715493_8	338963.Pcar_1584	2.963e-36	140.0	COG1433@1|root,COG1433@2|Bacteria,1MZ77@1224|Proteobacteria,42U3G@68525|delta/epsilon subdivisions,2WQ5N@28221|Deltaproteobacteria,43VC1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
LZS2_k127_6715493_14	747365.Thena_1647	4.869e-12	70.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
LZS2_k127_6715493_15	760568.Desku_2154	5.491e-11	68.0	COG1433@1|root,COG1433@2|Bacteria,1VM57@1239|Firmicutes,24WD4@186801|Clostridia	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
LZS2_k127_6715493_1	760568.Desku_2155	1.275e-165	533.0	COG3829@1|root,COG3829@2|Bacteria,1V0EF@1239|Firmicutes,24DXA@186801|Clostridia	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
LZS2_k127_6715493_4	1121405.dsmv_1147	1.47e-114	382.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2WKGK@28221|Deltaproteobacteria,2MI6V@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
LZS2_k127_6715493_10	443254.Marpi_1007	1.286e-31	141.0	COG1520@1|root,COG1520@2|Bacteria,2GD9T@200918|Thermotogae	200918|Thermotogae	S	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6715493_12	1047013.AQSP01000067_gene2196	4.833e-22	112.0	COG1413@1|root,COG1413@2|Bacteria,2NRMK@2323|unclassified Bacteria	2|Bacteria	C	HEAT repeats	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	HEAT_2,HEAT_PBS,NACHT,Peptidase_M9,Peptidase_M9_N
LZS2_k127_6715493_6	1379698.RBG1_1C00001G0230	9.249e-66	244.0	COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria	2|Bacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
LZS2_k127_6715493_9	104623.Ser39006_01015	1.801e-34	144.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,4012F@613|Serratia	1236|Gammaproteobacteria	L	TatD related DNase	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
LZS2_k127_6715493_0	518766.Rmar_2049	7.918e-288	910.0	COG1506@1|root,COG2706@1|root,COG1506@2|Bacteria,COG2706@2|Bacteria,4PIC9@976|Bacteroidetes,1FKAR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6767460_0	880073.Calab_1195	2.595e-261	840.0	COG0841@1|root,COG0841@2|Bacteria,2NQI6@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_6778299_1	448385.sce0941	3.087e-31	125.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,4307J@68525|delta/epsilon subdivisions,2WV6F@28221|Deltaproteobacteria,2YVCQ@29|Myxococcales	28221|Deltaproteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS2_k127_6778299_0	313606.M23134_05227	6.453e-135	462.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
LZS2_k127_6792017_8	604354.TSIB_1517	4.224e-74	258.0	COG0243@1|root,COG0493@1|root,COG1141@1|root,arCOG00349@2157|Archaea,arCOG01292@2157|Archaea,arCOG04862@2157|Archaea,2Y8AC@28890|Euryarchaeota,242J5@183968|Thermococci	183968|Thermococci	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20,Pyr_redox_2
LZS2_k127_6792017_9	1125863.JAFN01000001_gene2836	1.898e-60	214.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WNNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
LZS2_k127_6792017_11	1047013.AQSP01000139_gene2337	1.473e-53	196.0	COG1392@1|root,COG1392@2|Bacteria	2|Bacteria	P	Protein of unknown function DUF47	CP_0066	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
LZS2_k127_6792017_5	944479.JQLX01000012_gene1135	3.666e-131	430.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2WM6R@28221|Deltaproteobacteria,2M6XC@213113|Desulfurellales	28221|Deltaproteobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS2_k127_6792017_3	926550.CLDAP_16500	2.933e-150	482.0	COG0158@1|root,COG0158@2|Bacteria	2|Bacteria	G	fructose 1,6-bisphosphate 1-phosphatase activity	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C4836,ic_1306.c5329	FBPase
LZS2_k127_6792017_12	204669.Acid345_3322	3.261e-08	65.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia	204432|Acidobacteriia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6792017_4	237368.SCABRO_02835	7.518e-142	458.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,2IZ67@203682|Planctomycetes	203682|Planctomycetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
LZS2_k127_6792017_0	1047013.AQSP01000105_gene1443	0.0	1621.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2NQEH@2323|unclassified Bacteria	2|Bacteria	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
LZS2_k127_6792017_7	886293.Sinac_7496	2.316e-93	324.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS2_k127_6792017_6	765911.Thivi_2776	3.338e-106	349.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RSQ8@1236|Gammaproteobacteria,1WWKV@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM Succinate dehydrogenase fumarate reductase iron-sulphur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
LZS2_k127_6792017_1	1049564.TevJSym_ah01000	8.432e-287	892.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1J4I0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS2_k127_6792017_10	768671.ThimaDRAFT_4091	1.103e-55	201.0	COG2009@1|root,COG2009@2|Bacteria,1R7RY@1224|Proteobacteria,1RSM4@1236|Gammaproteobacteria,1WWTS@135613|Chromatiales	135613|Chromatiales	C	succinate dehydrogenase	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
LZS2_k127_6792017_2	313606.M23134_02452	2.058e-196	629.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,47KZ5@768503|Cytophagia	976|Bacteroidetes	G	PFAM Glycosyl Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_92
LZS2_k127_6802219_6	886293.Sinac_3436	8.48e-76	264.0	COG3228@1|root,COG3228@2|Bacteria,2IZES@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90,SEC-C
LZS2_k127_6802219_8	59374.Fisuc_2892	7.715e-28	127.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS2_k127_6802219_0	1121405.dsmv_1838	0.0	1112.0	COG0123@1|root,COG0454@1|root,COG0123@2|Bacteria,COG0456@2|Bacteria,1MU7P@1224|Proteobacteria,42NAQ@68525|delta/epsilon subdivisions,2WJPX@28221|Deltaproteobacteria,2MK5E@213118|Desulfobacterales	28221|Deltaproteobacteria	BKQ	Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Hist_deacetyl
LZS2_k127_6802219_4	1121405.dsmv_1837	4.443e-103	350.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,2MHWK@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
LZS2_k127_6802219_3	1121405.dsmv_1836	3.472e-153	491.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,2MIAX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
LZS2_k127_6802219_1	1121405.dsmv_1835	6.298e-179	569.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42MNR@68525|delta/epsilon subdivisions,2WJ70@28221|Deltaproteobacteria,2MICE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM lysine 2,3-aminomutase YodO family protein	kamA2	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
LZS2_k127_6802219_11	203119.Cthe_1756	6.946e-05	49.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3WGMI@541000|Ruminococcaceae	186801|Clostridia	L	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zf-ribbon_3,zinc_ribbon_2
LZS2_k127_6802219_10	247490.KSU1_C1294	1.848e-07	56.0	2DXHV@1|root,3453D@2|Bacteria,2J43G@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6802219_5	1167006.UWK_01691	4.299e-81	280.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,42NZ8@68525|delta/epsilon subdivisions,2WK0Y@28221|Deltaproteobacteria,2MPFD@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258,ko:K07262	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
LZS2_k127_6802219_2	521011.Mpal_1867	8.699e-160	520.0	COG0469@1|root,arCOG04120@2157|Archaea,2XU34@28890|Euryarchaeota,2N9DV@224756|Methanomicrobia	224756|Methanomicrobia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
LZS2_k127_6802219_7	469383.Cwoe_3127	9.07e-52	197.0	28NWQ@1|root,2ZBUI@2|Bacteria,2IGY4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6802219_12	1128421.JAGA01000002_gene365	0.0001851	48.0	COG0823@1|root,COG0823@2|Bacteria,2NPZ0@2323|unclassified Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
LZS2_k127_6802219_9	326427.Cagg_0924	2.709e-08	57.0	COG0823@1|root,COG0823@2|Bacteria,2GAJ0@200795|Chloroflexi,376FZ@32061|Chloroflexia	32061|Chloroflexia	U	PFAM WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS2_k127_6804123_2	331678.Cphamn1_1855	2.543e-41	162.0	COG0493@1|root,COG0493@2|Bacteria,1FDFY@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2
LZS2_k127_6804123_0	1125863.JAFN01000001_gene2834	1.375e-133	437.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
LZS2_k127_6804123_1	1125863.JAFN01000001_gene2833	1.229e-119	391.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
LZS2_k127_6819335_0	690850.Desaf_0617	4.277e-231	743.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
LZS2_k127_6819335_1	671143.DAMO_2824	3.41e-64	232.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
LZS2_k127_6825654_7	338963.Pcar_0686	6.691e-12	65.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,43U9V@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS2_k127_6825654_6	880072.Desac_1470	1.301e-17	82.0	COG0267@1|root,COG0267@2|Bacteria,1NJ67@1224|Proteobacteria,42V5X@68525|delta/epsilon subdivisions,2WSIR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
LZS2_k127_6825654_8	1121405.dsmv_3651	1.773e-06	51.0	COG0690@1|root,COG0690@2|Bacteria,1Q1BI@1224|Proteobacteria,42X4Z@68525|delta/epsilon subdivisions,2WSQ8@28221|Deltaproteobacteria,2MKUQ@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
LZS2_k127_6825654_3	1379698.RBG1_1C00001G1610	1.754e-55	205.0	COG0250@1|root,COG0250@2|Bacteria,2NPAP@2323|unclassified Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
LZS2_k127_6825654_2	1161902.HMPREF0378_1568	2.288e-60	211.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WCHH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
LZS2_k127_6825654_1	401526.TcarDRAFT_0987	1.081e-86	299.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4H228@909932|Negativicutes	909932|Negativicutes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
LZS2_k127_6825654_4	373903.Hore_01070	1.355e-37	147.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WANA@53433|Halanaerobiales	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
LZS2_k127_6825654_5	56780.SYN_00066	5.552e-37	143.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,42SHZ@68525|delta/epsilon subdivisions,2WPFZ@28221|Deltaproteobacteria,2MQJ9@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
LZS2_k127_6825654_0	1379698.RBG1_1C00001G1605	4.875e-205	651.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
LZS2_k127_6825654_9	1123401.JHYQ01000019_gene1462	1.963e-05	47.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,46008@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
LZS2_k127_6854698_6	880073.Calab_1130	3.461e-88	304.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
LZS2_k127_6854698_12	1121396.KB893095_gene4378	1.357e-21	102.0	COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,42TZJ@68525|delta/epsilon subdivisions,2WQB8@28221|Deltaproteobacteria,2MKJH@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Tripartite ATP-independent periplasmic transporter, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
LZS2_k127_6854698_2	1167006.UWK_01424	5.971e-147	478.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MI9P@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
LZS2_k127_6854698_10	945713.IALB_2117	1.128e-29	139.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C10,Phage-tail_3,Prophage_tail,SLH
LZS2_k127_6854698_13	326424.FRAAL2217	3.86e-19	104.0	COG1073@1|root,COG1520@1|root,COG1073@2|Bacteria,COG1520@2|Bacteria,2IJK1@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050
LZS2_k127_6854698_1	269799.Gmet_1637	4.723e-297	932.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
LZS2_k127_6854698_3	1125863.JAFN01000001_gene1760	2.007e-124	415.0	COG3581@1|root,COG3581@2|Bacteria,1PDHS@1224|Proteobacteria,43DP1@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
LZS2_k127_6854698_0	1125863.JAFN01000001_gene1761	0.0	1076.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
LZS2_k127_6854698_9	246194.CHY_0658	2.549e-51	193.0	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,24BG9@186801|Clostridia,42FWE@68295|Thermoanaerobacterales	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
LZS2_k127_6854698_5	204669.Acid345_4032	3.253e-88	307.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria,2JHT4@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,His_kinase
LZS2_k127_6854698_15	313628.LNTAR_09304	2.387e-06	61.0	COG1636@1|root,COG1636@2|Bacteria	2|Bacteria	C	queuosine biosynthetic process	queH	-	1.17.99.6,3.1.26.4	ko:K03470,ko:K09765	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03032	-	-	-	DUF208
LZS2_k127_6854698_14	880073.Calab_2549	2.252e-14	88.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS2_k127_6854698_4	1379698.RBG1_1C00001G1345	5.489e-111	380.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
LZS2_k127_6854698_11	574087.Acear_1887	7.059e-24	103.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,24R29@186801|Clostridia	186801|Clostridia	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NifU
LZS2_k127_6854698_7	1121033.AUCF01000001_gene2558	1.94e-86	300.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2JP8N@204441|Rhodospirillales	204441|Rhodospirillales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
LZS2_k127_6854698_16	717606.PaecuDRAFT_2023	0.0007134	52.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,26QKX@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS2_k127_6854698_8	404380.Gbem_2718	1.958e-79	295.0	COG1361@1|root,COG2885@1|root,COG4719@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,COG4719@2|Bacteria,1QW22@1224|Proteobacteria	1224|Proteobacteria	M	Ompa motb domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA,SdrD_B
LZS2_k127_6890141_0	1379698.RBG1_1C00001G1428	4.46e-63	239.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NS5I@2323|unclassified Bacteria	2|Bacteria	U	FlgD Ig-like domain	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,FlgD_ig,PKD,SLH
LZS2_k127_6890141_2	1120973.AQXL01000119_gene533	4.368e-55	211.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,279NS@186823|Alicyclobacillaceae	91061|Bacilli	L	IMS family HHH motif	dinB	GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
LZS2_k127_6890141_1	1379698.RBG1_1C00001G0684	2.837e-60	213.0	COG0277@1|root,COG0277@2|Bacteria,2NP1E@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104,ko:K18930	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS2_k127_696593_2	869210.Marky_1886	2.277e-84	289.0	COG0178@1|root,COG0178@2|Bacteria,1WI7J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS2_k127_696593_6	671143.DAMO_0447	1.138e-53	201.0	COG1694@1|root,COG3956@2|Bacteria,2NP9V@2323|unclassified Bacteria	2|Bacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	iJN678.sll1005	MazG,TP_methylase
LZS2_k127_696593_5	502025.Hoch_4033	4.51e-59	227.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2YZ61@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS2_k127_696593_13	1379698.RBG1_1C00001G0404	1.561e-19	93.0	2EAFJ@1|root,334IY@2|Bacteria,2NRZR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
LZS2_k127_696593_12	1078085.HMPREF1210_01598	7.827e-21	99.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,4HKN5@91061|Bacilli,26G71@186818|Planococcaceae	91061|Bacilli	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
LZS2_k127_696593_10	656519.Halsa_2112	5.174e-26	115.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,3WAYK@53433|Halanaerobiales	186801|Clostridia	K	PFAM Cupin	ydcN	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
LZS2_k127_696593_7	1125863.JAFN01000001_gene536	4.321e-43	170.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS2_k127_696593_3	1499967.BAYZ01000089_gene5013	1.699e-78	284.0	COG1519@1|root,COG1519@2|Bacteria,2NP5A@2323|unclassified Bacteria	2|Bacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	waaA	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K03439	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03016	-	GT30	-	Glycos_transf_N
LZS2_k127_696593_9	338966.Ppro_2754	4.619e-33	139.0	COG0535@1|root,COG0535@2|Bacteria,1RG5U@1224|Proteobacteria,42RKR@68525|delta/epsilon subdivisions,2WNUX@28221|Deltaproteobacteria,43VVF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
LZS2_k127_696593_11	883067.HMPREF9237_00086	1.422e-23	108.0	COG0009@1|root,COG0009@2|Bacteria,2GK2X@201174|Actinobacteria,4D3PC@85005|Actinomycetales	201174|Actinobacteria	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
LZS2_k127_696593_8	1229517.AMFD01000025_gene897	6.51e-37	149.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,1YBNQ@1357|Lactococcus	91061|Bacilli	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
LZS2_k127_696593_0	1125863.JAFN01000001_gene568	1.194e-138	455.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
LZS2_k127_696593_4	269799.Gmet_3244	1.915e-60	225.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43B2T@68525|delta/epsilon subdivisions,2X6GN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	larA	-	-	-	-	-	-	-	-	-	-	-	DUF2088
LZS2_k127_696593_1	1232410.KI421413_gene725	2.255e-104	347.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,42M16@68525|delta/epsilon subdivisions,2WM0V@28221|Deltaproteobacteria,43UMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Amino acid kinase family	cpkA	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS2_k127_6975267_11	1396418.BATQ01000141_gene3408	1.516e-22	110.0	COG1680@1|root,COG1680@2|Bacteria,46T7M@74201|Verrucomicrobia,2IWEF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS2_k127_6975267_1	1047013.AQSP01000139_gene2321	1.103e-205	653.0	COG1233@1|root,COG1233@2|Bacteria,2NQ26@2323|unclassified Bacteria	2|Bacteria	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13	ko:K09835,ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04787,R04798,R04800,R07512,R09691,R09692	RC01214,RC01960,RC02088,RC02605	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS2_k127_6975267_14	1279009.ADICEAN_00024	4.449e-06	53.0	COG1520@1|root,COG1520@2|Bacteria,4PNAK@976|Bacteroidetes,47YAF@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6975267_12	382464.ABSI01000012_gene2039	1.973e-08	62.0	COG3386@1|root,COG3386@2|Bacteria,46VF6@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6975267_10	309807.SRU_0707	5.571e-33	138.0	2BFSX@1|root,329MV@2|Bacteria,4P7GD@976|Bacteroidetes	309807.SRU_0707|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6975267_5	479434.Sthe_2389	3.937e-84	284.0	COG4122@1|root,COG4122@2|Bacteria,2G990@200795|Chloroflexi,27ZCN@189775|Thermomicrobia	189775|Thermomicrobia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
LZS2_k127_6975267_4	1047013.AQSP01000099_gene1506	6.519e-104	351.0	COG1355@1|root,COG1355@2|Bacteria,2NQS3@2323|unclassified Bacteria	2|Bacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
LZS2_k127_6975267_2	1121875.KB907555_gene370	1.916e-177	563.0	COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes,1HZ0Q@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM DeoC LacD family aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
LZS2_k127_6975267_13	1524467.IV04_21815	7.682e-07	63.0	COG3391@1|root,COG3391@2|Bacteria,1PDS2@1224|Proteobacteria,1RPZQ@1236|Gammaproteobacteria,401ZQ@613|Serratia	1236|Gammaproteobacteria	S	PQQ-like domain	yncE	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS2_k127_6975267_3	880073.Calab_3366	3.127e-122	401.0	COG2248@1|root,COG2248@2|Bacteria	2|Bacteria	-	-	VP1164	-	-	ko:K07022,ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
LZS2_k127_6975267_6	1121405.dsmv_3202	2.594e-74	253.0	COG5561@1|root,COG5561@2|Bacteria,1RFC4@1224|Proteobacteria,42S7T@68525|delta/epsilon subdivisions,2WNU0@28221|Deltaproteobacteria,2MJYT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
LZS2_k127_6975267_8	329726.AM1_4632	2.61e-54	206.0	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
LZS2_k127_6975267_0	234267.Acid_5088	1.937e-214	677.0	COG1012@1|root,COG1012@2|Bacteria,3Y3CY@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS2_k127_6975267_9	234267.Acid_4599	1.855e-40	154.0	COG0393@1|root,COG0393@2|Bacteria,3Y50H@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS2_k127_6975267_7	1047013.AQSP01000126_gene2741	5.315e-61	212.0	COG0339@1|root,COG0339@2|Bacteria,2NP9Q@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M3	prlC	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
LZS2_k127_6995591_2	1121428.DESHY_30086___1	1.624e-158	506.0	COG2221@1|root,COG2221@2|Bacteria,1TZD2@1239|Firmicutes,24DEF@186801|Clostridia,2610K@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM sulfite reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
LZS2_k127_6995591_1	387631.Asulf_00916	8.313e-173	550.0	COG2221@1|root,arCOG02057@2157|Archaea	2157|Archaea	C	PFAM nitrite and sulphite reductase 4Fe-4S	-	GO:0005575,GO:0016020	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
LZS2_k127_6995591_3	706587.Desti_2669	3.931e-155	498.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2MQS4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	dsrP	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
LZS2_k127_6995591_4	335543.Sfum_1149	7.807e-86	291.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MQSD@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
LZS2_k127_6995591_5	555779.Dthio_PD1008	2.053e-36	144.0	arCOG10385@1|root,32SEM@2|Bacteria,1N1IG@1224|Proteobacteria,42TMW@68525|delta/epsilon subdivisions,2WQBW@28221|Deltaproteobacteria,2MC03@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_6995591_0	706587.Desti_2672	1.587e-206	646.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,42M60@68525|delta/epsilon subdivisions,2WITJ@28221|Deltaproteobacteria,2MQT6@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrK	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
LZS2_k127_6999175_1	338969.Rfer_4082	6.543e-39	156.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,2VM47@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Decaheme c-type cytochrome, DmsE family	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS2_k127_6999175_0	234267.Acid_1495	5.488e-81	280.0	COG1131@1|root,COG1131@2|Bacteria,3Y7MA@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_6999175_2	523791.Kkor_1780	1.888e-18	94.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,1PM1H@1224|Proteobacteria,1RUN8@1236|Gammaproteobacteria,1XQN3@135619|Oceanospirillales	135619|Oceanospirillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_7020551_2	1408473.JHXO01000001_gene2146	1.616e-99	339.0	COG1453@1|root,COG1453@2|Bacteria,4NJU2@976|Bacteroidetes,2G2UD@200643|Bacteroidia	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
LZS2_k127_7020551_4	879212.DespoDRAFT_00348	2.822e-18	94.0	2AR2D@1|root,31GBD@2|Bacteria,1QE32@1224|Proteobacteria,432R1@68525|delta/epsilon subdivisions,2WXPH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4412)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
LZS2_k127_7020551_5	1168034.FH5T_14775	1.425e-17	89.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7020551_3	1406840.Q763_16015	3.028e-21	102.0	2A9HF@1|root,30YPN@2|Bacteria,4PCJF@976|Bacteroidetes,1I9PE@117743|Flavobacteriia,2NXBX@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7020551_6	1267534.KB906754_gene3483	1.931e-05	56.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF11,VCBS
LZS2_k127_7020551_1	452637.Oter_2107	7.005e-210	662.0	COG0034@1|root,COG0034@2|Bacteria,46SSU@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
LZS2_k127_7020551_0	1047013.AQSP01000105_gene1461	8.305e-231	744.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	dap2	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
LZS2_k127_704176_6	525904.Tter_1673	1.232e-39	149.0	COG2185@1|root,COG2185@2|Bacteria,2NPGA@2323|unclassified Bacteria	2|Bacteria	I	Cobalamin B12-binding	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
LZS2_k127_704176_4	1499683.CCFF01000015_gene3339	2.713e-139	452.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,36DR1@31979|Clostridiaceae	186801|Clostridia	I	acyl-CoA dehydrogenase	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS2_k127_704176_3	216595.PFLU_2150	1.06e-147	477.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1YM4C@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	I	Belongs to the thiolase family	atoB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS2_k127_704176_5	869210.Marky_0879	1.289e-111	368.0	COG1250@1|root,COG1250@2|Bacteria,1WIN8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
LZS2_k127_704176_12	1408813.AYMG01000023_gene2034	3.433e-05	48.0	2APBA@1|root,31EDH@2|Bacteria,4NSFA@976|Bacteroidetes,1ITSE@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
LZS2_k127_704176_8	215803.DB30_0733	1.18e-31	128.0	COG2840@1|root,COG2840@2|Bacteria,1QX48@1224|Proteobacteria,43BWQ@68525|delta/epsilon subdivisions,2X77I@28221|Deltaproteobacteria,2Z3DP@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
LZS2_k127_704176_10	1008457.BAEX01000079_gene3067	2.925e-14	81.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia,47IUJ@76831|Myroides	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
LZS2_k127_704176_7	880072.Desac_0969	1.087e-31	132.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria,2MRYD@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
LZS2_k127_704176_1	1304284.L21TH_0800	1.683e-213	677.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,36H9W@31979|Clostridiaceae	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS2_k127_704176_9	469618.FVAG_02486	2.746e-15	83.0	COG0511@1|root,COG0511@2|Bacteria,37A9G@32066|Fusobacteria	32066|Fusobacteria	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
LZS2_k127_704176_2	1313301.AUGC01000001_gene1642	5.163e-162	527.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS2_k127_704176_0	485913.Krac_12092	1.054e-233	733.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS2_k127_704176_11	1294265.JCM21738_4808	9.105e-06	56.0	COG4412@1|root,COG4412@2|Bacteria,1UYZF@1239|Firmicutes,4HBRX@91061|Bacilli,1ZERF@1386|Bacillus	91061|Bacilli	S	Immune inhibitor A peptidase M6	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M6
LZS2_k127_7049783_5	1090318.ATTI01000001_gene1125	8.815e-43	169.0	2ARG0@1|root,31GS6@2|Bacteria,1P9KI@1224|Proteobacteria,2UXWA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7049783_1	1232410.KI421418_gene2118	0.0	1093.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,42MY0@68525|delta/epsilon subdivisions,2WM7X@28221|Deltaproteobacteria,43SYK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Monomeric isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
LZS2_k127_7049783_4	1384056.N787_09610	6.97e-108	372.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1X4VE@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
LZS2_k127_7049783_0	575540.Isop_1210	0.0	1365.0	COG4447@1|root,COG4447@2|Bacteria,2J1J5@203682|Planctomycetes	203682|Planctomycetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
LZS2_k127_7049783_2	1123508.JH636439_gene1271	3.914e-150	481.0	COG1064@1|root,COG1064@2|Bacteria,2IY4H@203682|Planctomycetes	203682|Planctomycetes	C	alcohol dehydrogenase	-	-	-	ko:K12957	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS2_k127_7049783_6	690850.Desaf_1072	1.597e-33	134.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MGUH@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS2_k127_7049783_3	1047013.AQSP01000105_gene1439	3.787e-114	382.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	MA20_31530	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS2_k127_7049783_7	1254432.SCE1572_24695	2.776e-33	141.0	COG0500@1|root,COG2226@2|Bacteria,1PVPS@1224|Proteobacteria,43DGN@68525|delta/epsilon subdivisions,2X8NF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7050211_1	1379698.RBG1_1C00001G1616	1.003e-116	411.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS2_k127_7050211_2	1121918.ARWE01000001_gene2968	6.597e-97	334.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2X75V@28221|Deltaproteobacteria,43UEH@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Single cache domain 3	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD,HD_5,sCache_3_2
LZS2_k127_7050211_4	1122244.AUGF01000008_gene136	1.866e-05	48.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,3NM4V@468|Moraxellaceae	1236|Gammaproteobacteria	M	Lipocalin-like domain	blc	GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
LZS2_k127_7050211_0	1123400.KB904791_gene46	2.99e-277	868.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,463MN@72273|Thiotrichales	72273|Thiotrichales	I	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS2_k127_7097797_0	1379698.RBG1_1C00001G0278	5.137e-231	729.0	COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS2_k127_7097797_11	1078083.HMPREF1208_01358	0.0002677	44.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli,4GXR5@90964|Staphylococcaceae	91061|Bacilli	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
LZS2_k127_7097797_10	880073.Calab_1441	1.588e-09	71.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
LZS2_k127_7097797_5	1499967.BAYZ01000076_gene842	2.098e-62	242.0	COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
LZS2_k127_7097797_2	1123401.JHYQ01000010_gene2451	6.071e-74	259.0	COG2227@1|root,COG2227@2|Bacteria,1NJV4@1224|Proteobacteria,1T1GP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
LZS2_k127_7097797_4	1379698.RBG1_1C00001G1205	1.564e-71	259.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_7097797_8	1333523.L593_00415	6.73e-12	74.0	COG0500@1|root,arCOG04989@2157|Archaea,2Y79A@28890|Euryarchaeota,23ZQ6@183963|Halobacteria	183963|Halobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7097797_6	1517682.HW49_07105	2.529e-17	94.0	COG3919@1|root,COG3919@2|Bacteria,4NMVY@976|Bacteroidetes,2FS4C@200643|Bacteroidia	976|Bacteroidetes	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,CPSase_L_D2,Dala_Dala_lig_C
LZS2_k127_7097797_9	1379698.RBG1_1C00001G0993	2.369e-11	75.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
LZS2_k127_7097797_3	1379698.RBG1_1C00001G1206	1.264e-71	254.0	COG1215@1|root,COG1215@2|Bacteria,2NQN7@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS2_k127_7097797_1	1304885.AUEY01000054_gene184	3.457e-131	430.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2MIIQ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS2_k127_7097797_7	477974.Daud_1110	3.315e-17	85.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,2606G@186807|Peptococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS2_k127_7123451_1	1158318.ATXC01000001_gene1138	8.166e-108	355.0	COG0215@1|root,COG0215@2|Bacteria,2G3JG@200783|Aquificae	200783|Aquificae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
LZS2_k127_7123451_2	1379698.RBG1_1C00001G0842	3.234e-74	263.0	COG1181@1|root,COG1181@2|Bacteria,2NPB2@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
LZS2_k127_7123451_0	370438.PTH_0293	1.38e-136	450.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,26070@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
LZS2_k127_7164084_1	1121430.JMLG01000012_gene1991	4.066e-43	170.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,2602M@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
LZS2_k127_7164084_2	1200792.AKYF01000019_gene4698	8.566e-11	67.0	COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli	91061|Bacilli	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
LZS2_k127_7164084_0	1379698.RBG1_1C00001G1123	4.617e-174	560.0	COG1418@1|root,COG1418@2|Bacteria,2NNU5@2323|unclassified Bacteria	2|Bacteria	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
LZS2_k127_7167823_5	1379270.AUXF01000007_gene1013	4.666e-60	231.0	COG0708@1|root,COG1404@1|root,COG0708@2|Bacteria,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.24.3	ko:K01387,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Autotransporter,Exo_endo_phos,He_PIG,Peptidase_S8
LZS2_k127_7167823_0	404589.Anae109_3441	5.834e-223	707.0	COG4690@1|root,COG4690@2|Bacteria,1R4YQ@1224|Proteobacteria,42NQZ@68525|delta/epsilon subdivisions,2WMGS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM peptidase U34 dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
LZS2_k127_7167823_2	344747.PM8797T_05550	8.019e-129	420.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,2IZS3@203682|Planctomycetes	203682|Planctomycetes	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
LZS2_k127_7167823_4	1379698.RBG1_1C00001G0518	3.158e-95	347.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS2_k127_7167823_3	485916.Dtox_1611	2.129e-112	370.0	COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS2_k127_7167823_1	309807.SRU_0349	6.556e-146	483.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
LZS2_k127_7234756_9	1347086.CCBA010000012_gene2030	2.886e-10	63.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7234756_2	1195236.CTER_1970	5.659e-83	291.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_7234756_8	459349.CLOAM1790	1.204e-21	111.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
LZS2_k127_7234756_1	926550.CLDAP_04870	7.21e-102	364.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS2_k127_7234756_3	1219065.VPR01S_07_00490	3.751e-78	277.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,1S0BA@1236|Gammaproteobacteria,1XVYM@135623|Vibrionales	135623|Vibrionales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_7234756_5	997884.HMPREF1068_02552	1.131e-64	233.0	COG0535@1|root,COG0535@2|Bacteria,4NEKZ@976|Bacteroidetes,2FNV0@200643|Bacteroidia,4AP4J@815|Bacteroidaceae	976|Bacteroidetes	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS2_k127_7234756_4	1304872.JAGC01000009_gene650	7.093e-65	236.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WPW4@28221|Deltaproteobacteria,2MCTH@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_7234756_6	1122182.KB903814_gene3226	1.047e-55	202.0	COG0110@1|root,COG0110@2|Bacteria,2H5M0@201174|Actinobacteria,4DF0N@85008|Micromonosporales	201174|Actinobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
LZS2_k127_7234756_0	1267533.KB906735_gene4487	1.165e-107	359.0	COG0673@1|root,COG0673@2|Bacteria,3Y486@57723|Acidobacteria,2JHJI@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS2_k127_7234756_7	309801.trd_A0816	8.317e-25	104.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
LZS2_k127_7241325_1	237368.SCABRO_03144	4.449e-155	503.0	COG3379@1|root,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_7241325_3	247490.KSU1_C1247	3.16e-64	225.0	COG0529@1|root,COG0529@2|Bacteria,2IYUQ@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
LZS2_k127_7241325_2	1047013.AQSP01000067_gene2199	6.11e-123	410.0	COG3379@1|root,COG3379@2|Bacteria,2NQEW@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_7241325_0	502025.Hoch_2285	1.094e-202	651.0	COG0696@1|root,COG3379@1|root,COG0696@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42PUB@68525|delta/epsilon subdivisions,2WMH5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS2_k127_7256349_0	1191523.MROS_1723	4.313e-193	619.0	COG1185@1|root,COG1185@2|Bacteria	2|Bacteria	J	polyribonucleotide nucleotidyltransferase activity	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
LZS2_k127_7256349_1	1379698.RBG1_1C00001G1161	1.356e-90	313.0	COG0612@1|root,COG0612@2|Bacteria,2NNW3@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_7256349_2	1379698.RBG1_1C00001G1162	2.672e-41	163.0	COG0726@1|root,COG0726@2|Bacteria,2NPY1@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Polysacc_deac_1
LZS2_k127_7256349_3	1313304.CALK_0827	6.851e-34	143.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.133,2.5.1.39,2.5.1.62	ko:K03179,ko:K04040	ko00130,ko00860,ko01100,ko01110,map00130,map00860,map01100,map01110	M00117	R05000,R05615,R06284,R09067,R11514,R11517	RC00020,RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS2_k127_7256349_4	1379281.AVAG01000094_gene676	4.905e-07	61.0	COG0484@1|root,COG0484@2|Bacteria,1QXUZ@1224|Proteobacteria,43C7N@68525|delta/epsilon subdivisions,2X7HY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
LZS2_k127_7263877_1	880073.Calab_3212	4.046e-266	838.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
LZS2_k127_7263877_6	153948.NAL212_1226	8.6e-10	66.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,3733X@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
LZS2_k127_7263877_0	373903.Hore_14590	2e-275	873.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WA6Y@53433|Halanaerobiales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
LZS2_k127_7263877_4	368408.Tpen_1449	2.139e-32	137.0	COG0382@1|root,arCOG00476@2157|Archaea,2XQXW@28889|Crenarchaeota	28889|Crenarchaeota	H	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	-	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
LZS2_k127_7263877_5	1379698.RBG1_1C00001G1726	2.963e-25	121.0	29YZ1@1|root,30KVZ@2|Bacteria,2NRNQ@2323|unclassified Bacteria	2|Bacteria	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
LZS2_k127_7263877_3	237368.SCABRO_03253	4.492e-36	154.0	COG0457@1|root,COG0457@2|Bacteria	237368.SCABRO_03253|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7263877_2	639282.DEFDS_0024	5.482e-39	158.0	COG1100@1|root,COG1100@2|Bacteria,2GEYH@200930|Deferribacteres	200930|Deferribacteres	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
LZS2_k127_7300375_0	1379698.RBG1_1C00001G0474	3.544e-31	128.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
LZS2_k127_7300375_1	481448.Minf_1433	1.796e-13	81.0	COG0392@1|root,COG0392@2|Bacteria,46YYT@74201|Verrucomicrobia,37GP8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS2_k127_7303894_0	720554.Clocl_2233	6.851e-140	454.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS2_k127_7303894_6	1443665.JACA01000053_gene3281	1.915e-44	184.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia,2YHH1@290174|Aquimarina	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS2_k127_7303894_7	717231.Flexsi_1568	1.008e-33	149.0	COG0760@1|root,COG0760@2|Bacteria,2GEX1@200930|Deferribacteres	200930|Deferribacteres	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
LZS2_k127_7303894_8	635013.TherJR_1115	7.072e-11	65.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,24V8A@186801|Clostridia,262T4@186807|Peptococcaceae	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
LZS2_k127_7303894_9	525903.Taci_0893	9.396e-07	57.0	COG1316@1|root,COG1316@2|Bacteria,3TA77@508458|Synergistetes	508458|Synergistetes	K	TIGRFAM cell envelope-related function transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
LZS2_k127_7303894_5	1183377.Py04_0129	1.36e-46	173.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,242M1@183968|Thermococci	183968|Thermococci	F	Hit family	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
LZS2_k127_7303894_3	194439.CT0251	1.773e-69	244.0	COG1207@1|root,COG1207@2|Bacteria,1FDEZ@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.23	ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
LZS2_k127_7303894_2	1382304.JNIL01000001_gene811	1.177e-82	283.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,2784W@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
LZS2_k127_7303894_1	643648.Slip_0136	7.302e-100	333.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,42JSG@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
LZS2_k127_7303894_4	671143.DAMO_2311	1.745e-60	216.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
LZS2_k127_7333315_0	247490.KSU1_B0006	6.784e-243	776.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,2IXFM@203682|Planctomycetes	203682|Planctomycetes	C	COG0493 NADPH-dependent glutamate synthase beta chain and	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
LZS2_k127_7333315_2	316056.RPC_1006	1.161e-28	124.0	COG0493@1|root,COG0543@1|root,COG1633@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,COG1633@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
LZS2_k127_7333315_1	880073.Calab_1976	1.214e-66	235.0	COG1387@1|root,COG1387@2|Bacteria,2NNNK@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase X family	dpx	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
LZS2_k127_7376410_0	589924.Ferp_0317	5.341e-229	730.0	COG0458@1|root,arCOG01594@2157|Archaea,2XTVE@28890|Euryarchaeota,245PG@183980|Archaeoglobi	183980|Archaeoglobi	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
LZS2_k127_7376410_1	292415.Tbd_0747	2.759e-62	223.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,1KSGX@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
LZS2_k127_7376410_2	304371.MCP_0893	1.388e-25	120.0	COG0438@1|root,arCOG01403@2157|Archaea,2XXCQ@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_7376410_3	936136.ARRT01000006_gene1773	8.033e-17	84.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,2U8DY@28211|Alphaproteobacteria,4B9JJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
LZS2_k127_7385001_2	742738.HMPREF9460_01577	6.219e-05	47.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,2699G@186813|unclassified Clostridiales	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
LZS2_k127_7385001_0	517418.Ctha_1205	5.945e-95	324.0	COG0075@1|root,COG0075@2|Bacteria,1FEKT@1090|Chlorobi	1090|Chlorobi	H	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS2_k127_7385001_1	1125863.JAFN01000001_gene1833	1.401e-90	310.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
LZS2_k127_7388031_2	518766.Rmar_2366	3.606e-158	516.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1FIKX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS2_k127_7388031_0	85643.Tmz1t_1473	2.323e-190	619.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,2KUW0@206389|Rhodocyclales	206389|Rhodocyclales	M	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
LZS2_k127_7388031_4	1094980.Mpsy_0078	2.111e-32	130.0	COG0432@1|root,arCOG04214@2157|Archaea,2XXSW@28890|Euryarchaeota,2NATS@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS2_k127_7388031_1	945713.IALB_2167	3.747e-189	606.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64,VWA
LZS2_k127_7388031_7	1278073.MYSTI_03079	1.022e-13	78.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7388031_8	1122222.AXWR01000037_gene279	1.007e-09	74.0	COG2372@1|root,COG4733@1|root,COG2372@2|Bacteria,COG4733@2|Bacteria,1WN17@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
LZS2_k127_7388031_10	1209984.BN978_06112	2.579e-05	59.0	COG3391@1|root,COG5295@1|root,COG3391@2|Bacteria,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K11904,ko:K12287,ko:K21449	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.40.2,3.A.23.1	-	-	YadA_stalk
LZS2_k127_7388031_9	313606.M23134_01445	1.96e-05	60.0	COG3291@1|root,COG5184@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,4NPFW@976|Bacteroidetes,47X9T@768503|Cytophagia	976|Bacteroidetes	DZ	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	DUF5013,TIG
LZS2_k127_7388031_5	1123322.KB904677_gene3136	1.234e-16	97.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase,TIG
LZS2_k127_7388031_6	880073.Calab_3213	8.941e-14	87.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Arylsulfotrans,PQQ_2
LZS2_k127_7403099_5	1434325.AZQN01000003_gene2172	3.966e-12	71.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS2_k127_7403099_3	56780.SYN_02874	3.456e-97	328.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,42M1U@68525|delta/epsilon subdivisions,2WKK5@28221|Deltaproteobacteria,2MRYB@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	pfkB family carbohydrate kinase	-	-	2.7.1.15,2.7.1.4	ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS2_k127_7403099_2	1408473.JHXO01000008_gene2803	1.458e-118	387.0	COG0648@1|root,COG0648@2|Bacteria,4NJDP@976|Bacteroidetes,2FPM6@200643|Bacteroidia	976|Bacteroidetes	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
LZS2_k127_7403099_0	1519464.HY22_10360	2.952e-209	664.0	COG0154@1|root,COG0154@2|Bacteria,1FDMC@1090|Chlorobi	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS2_k127_7403099_6	1045009.AFXQ01000005_gene1356	1.071e-06	58.0	COG3402@1|root,COG3402@2|Bacteria,2IR88@201174|Actinobacteria,1W9M1@1268|Micrococcaceae	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
LZS2_k127_7403099_1	1121930.AQXG01000001_gene1202	8.988e-186	617.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_7403099_4	1121104.AQXH01000001_gene1412	3.583e-68	238.0	COG0841@1|root,COG0841@2|Bacteria,4NGCI@976|Bacteroidetes	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_742325_6	1168289.AJKI01000001_gene3677	1.463e-39	156.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes,2G0E5@200643|Bacteroidia,3XKPR@558415|Marinilabiliaceae	976|Bacteroidetes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS2_k127_742325_4	383372.Rcas_1763	7.09e-65	239.0	COG1131@1|root,COG1131@2|Bacteria,2G7Q5@200795|Chloroflexi,376MI@32061|Chloroflexia	32061|Chloroflexia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_742325_1	517417.Cpar_1049	1.159e-86	292.0	COG1131@1|root,COG1131@2|Bacteria,1FDTT@1090|Chlorobi	1090|Chlorobi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_742325_3	1047013.AQSP01000139_gene2333	7.891e-83	290.0	COG0842@1|root,COG0842@2|Bacteria,2NPA6@2323|unclassified Bacteria	2|Bacteria	V	ABC-type multidrug transport system, permease component	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_742325_2	96561.Dole_0811	2.744e-85	307.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2MJ98@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS2_k127_742325_0	1379698.RBG1_1C00001G0607	2.733e-92	325.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS2_k127_742325_5	593750.Metfor_1976	1.574e-48	199.0	COG2208@1|root,arCOG02362@1|root,arCOG02362@2157|Archaea,arCOG06893@2157|Archaea,2Y2MD@28890|Euryarchaeota	2157|Archaea	T	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
LZS2_k127_7435760_6	96561.Dole_2408	3.135e-34	138.0	COG2194@1|root,COG2194@2|Bacteria,1NJEC@1224|Proteobacteria	1224|Proteobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7435760_0	272134.KB731324_gene5867	3.166e-268	846.0	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,1H71F@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
LZS2_k127_7435760_7	118173.KB235914_gene2268	2.607e-23	101.0	COG0298@1|root,COG0298@2|Bacteria,1G9FZ@1117|Cyanobacteria,1HDBE@1150|Oscillatoriales	1117|Cyanobacteria	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
LZS2_k127_7435760_2	518766.Rmar_2595	1.532e-162	518.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes	976|Bacteroidetes	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
LZS2_k127_7435760_4	518766.Rmar_2596	2.501e-133	434.0	COG0309@1|root,COG0309@2|Bacteria,4NG57@976|Bacteroidetes	976|Bacteroidetes	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
LZS2_k127_7435760_3	502025.Hoch_1910	2.299e-144	468.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,42NHC@68525|delta/epsilon subdivisions,2WJQJ@28221|Deltaproteobacteria,2YUHD@29|Myxococcales	28221|Deltaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
LZS2_k127_7435760_5	1191523.MROS_2381	1.2e-35	139.0	COG3288@1|root,COG3288@2|Bacteria	2|Bacteria	C	NAD(P)+ transhydrogenase (AB-specific) activity	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
LZS2_k127_7435760_1	889378.Spiaf_2787	5.73e-169	542.0	COG1282@1|root,COG1282@2|Bacteria,2J693@203691|Spirochaetes	203691|Spirochaetes	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
LZS2_k127_743609_2	1280681.AUJZ01000001_gene1067	9.195e-125	408.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,4BWA6@830|Butyrivibrio	186801|Clostridia	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
LZS2_k127_743609_3	1321786.HMPREF1992_01327	3.361e-93	318.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H28V@909932|Negativicutes	909932|Negativicutes	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
LZS2_k127_743609_4	1384054.N790_14195	1.873e-53	192.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1X5Z3@135614|Xanthomonadales	135614|Xanthomonadales	S	Nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
LZS2_k127_743609_0	1144275.COCOR_01282	1.564e-222	711.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,2YUNF@29|Myxococcales	28221|Deltaproteobacteria	K	Tex-like protein N-terminal domain	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
LZS2_k127_743609_1	96561.Dole_3023	1e-132	436.0	COG1032@1|root,COG1032@2|Bacteria,1PTN9@1224|Proteobacteria,42MG9@68525|delta/epsilon subdivisions,2WJYU@28221|Deltaproteobacteria,2MIRY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_7443349_3	1121370.AQUY01000002_gene1562	2.984e-15	83.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,22JMQ@1653|Corynebacteriaceae	201174|Actinobacteria	I	Acetyl propionyl-CoA carboxylase, alpha	accA1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01965,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2501c	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
LZS2_k127_7443349_1	760142.Hipma_0822	1.852e-166	537.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,2M6KR@213113|Desulfurellales	28221|Deltaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS2_k127_7443349_2	1123033.ARNF01000083_gene1694	8.084e-72	252.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,3NIIF@468|Moraxellaceae	1236|Gammaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	liuC	-	4.2.1.18,5.3.3.18	ko:K13766,ko:K15866	ko00280,ko00360,ko01100,ko01120,map00280,map00360,map01100,map01120	M00036	R02085,R09837,R09839	RC00004,RC00326,RC02416,RC02689,RC03003	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS2_k127_7443349_0	1382306.JNIM01000001_gene2570	7.165e-244	762.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS2_k127_7469809_0	1047013.AQSP01000091_gene642	0.0	1128.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	sfrB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944	1.12.1.3,1.17.1.10,1.6.5.3	ko:K00335,ko:K15022,ko:K18331	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_2080	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
LZS2_k127_7469809_2	1047013.AQSP01000091_gene643	2.288e-80	277.0	COG3383@1|root,COG3383@2|Bacteria,2NNXH@2323|unclassified Bacteria	2|Bacteria	C	Iron hydrogenase small subunit	-	-	1.12.1.3,1.17.1.9,1.6.5.3	ko:K00123,ko:K00336,ko:K18332	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iHN637.CLJU_RS03470	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_21,Fer4_7,NADH-G_4Fe-4S_3
LZS2_k127_7469809_1	1047013.AQSP01000091_gene644	7.927e-246	769.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	yahG	-	-	-	-	-	-	-	-	-	-	-	DUF1116,FMN_dh,Glu_synthase
LZS2_k127_7479703_6	1304872.JAGC01000009_gene382	2.016e-45	178.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,42QEH@68525|delta/epsilon subdivisions,2WKVC@28221|Deltaproteobacteria,2MAS2@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CBP_BcsQ,ParA,Response_reg
LZS2_k127_7479703_1	748280.NH8B_2376	1.198e-165	533.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2VJWJ@28216|Betaproteobacteria,2KTWA@206351|Neisseriales	206351|Neisseriales	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS2_k127_7479703_5	1232437.KL662063_gene3998	6.515e-55	204.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,42QS0@68525|delta/epsilon subdivisions,2WMU6@28221|Deltaproteobacteria,2MK5B@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS2_k127_7479703_4	279714.FuraDRAFT_0830	9.047e-60	218.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2VIA4@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type II secretion system	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS2_k127_7479703_7	1191523.MROS_2238	1.11e-22	115.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	CBM_6,fn3
LZS2_k127_7479703_2	945713.IALB_2321	3.25e-121	423.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
LZS2_k127_7479703_3	935948.KE386494_gene944	8.203e-103	351.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS2_k127_7479703_0	485915.Dret_1750	2.37e-179	576.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
LZS2_k127_7503982_1	1379270.AUXF01000001_gene1861	2.659e-24	115.0	COG1404@1|root,COG2247@1|root,COG5492@1|root,COG1404@2|Bacteria,COG2247@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.4.24.3	ko:K01387,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Peptidase_S8,SLH
LZS2_k127_7503982_3	1187848.AJYQ01000128_gene580	2.15e-15	79.0	COG0471@1|root,COG0471@2|Bacteria,1R6QF@1224|Proteobacteria,1RQIG@1236|Gammaproteobacteria,1XTZX@135623|Vibrionales	135623|Vibrionales	P	COG0471 Di- and tricarboxylate transporters	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS2_k127_7503982_0	290402.Cbei_2963	2.71e-38	156.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,2495M@186801|Clostridia,36DFU@31979|Clostridiaceae	186801|Clostridia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
LZS2_k127_7503982_2	1296416.JACB01000057_gene1495	5.518e-23	103.0	COG0526@1|root,COG0526@2|Bacteria,4NQI3@976|Bacteroidetes,1I2TH@117743|Flavobacteriia,2YHR4@290174|Aquimarina	976|Bacteroidetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_9
LZS2_k127_7508605_4	880073.Calab_1777	2.487e-11	76.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.2.1.99	ko:K06113,ko:K12685	-	-	-	-	ko00000,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Cu_amine_oxidN1,Peptidase_S8,SLH
LZS2_k127_7508605_1	945713.IALB_0461	1.559e-115	398.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS2_k127_7508605_0	243231.GSU0580	0.0	1151.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43TQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS2_k127_7508605_2	1121403.AUCV01000005_gene233	1.761e-17	89.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2MHV1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
LZS2_k127_7508605_6	319795.Dgeo_1746	5.58e-07	61.0	COG0366@1|root,COG3391@1|root,COG0366@2|Bacteria,COG3391@2|Bacteria,1WK9J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CarboxypepD_reg
LZS2_k127_7508605_3	1519464.HY22_08670	7.237e-15	87.0	COG1555@1|root,COG1555@2|Bacteria,1FE73@1090|Chlorobi	1090|Chlorobi	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
LZS2_k127_7508605_5	771875.Ferpe_1782	4.272e-10	72.0	COG0296@1|root,COG4945@1|root,COG0296@2|Bacteria,COG4945@2|Bacteria,2GC51@200918|Thermotogae	200918|Thermotogae	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Glucodextran_C,Glyco_hydro_57
LZS2_k127_7517206_1	331678.Cphamn1_0905	2.743e-134	438.0	COG0265@1|root,COG0265@2|Bacteria,1FDIE@1090|Chlorobi	1090|Chlorobi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_7517206_8	1379698.RBG1_1C00001G0053	1.802e-19	94.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2,Rhodanese,Rubrerythrin
LZS2_k127_7517206_6	700598.Niako_0486	1.434e-57	214.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
LZS2_k127_7517206_3	477974.Daud_0439	3.448e-101	338.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia,262MF@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS2_k127_7517206_4	879212.DespoDRAFT_00589	1.441e-100	342.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS2_k127_7517206_2	945713.IALB_1030	9.195e-109	368.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	nagB	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
LZS2_k127_7517206_5	1408473.JHXO01000008_gene2653	1.776e-69	241.0	COG2120@1|root,COG2120@2|Bacteria,4NM6J@976|Bacteroidetes	976|Bacteroidetes	S	PFAM GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS2_k127_7517206_0	1408473.JHXO01000008_gene2652	2.962e-200	628.0	COG0438@1|root,COG0438@2|Bacteria,4NKIM@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
LZS2_k127_7517206_7	485917.Phep_1537	5.482e-23	111.0	COG3408@1|root,COG3408@2|Bacteria,4NGZM@976|Bacteroidetes,1IVM9@117747|Sphingobacteriia	976|Bacteroidetes	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100,S6PP
LZS2_k127_7518397_31	1125712.HMPREF1316_0265	6.766e-05	51.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CUM8@84998|Coriobacteriia	84998|Coriobacteriia	D	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS2_k127_7518397_23	665571.STHERM_c10790	3.485e-07	62.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
LZS2_k127_7518397_30	574087.Acear_0772	3.639e-05	55.0	COG0810@1|root,COG0810@2|Bacteria,1VN7X@1239|Firmicutes,25413@186801|Clostridia,3WC1R@53433|Halanaerobiales	186801|Clostridia	M	TIGRFAM TonB family protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
LZS2_k127_7518397_21	1349767.GJA_399	3.952e-09	63.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VSVW@28216|Betaproteobacteria,4780C@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Biopolymer transport	exbD	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS2_k127_7518397_22	1040989.AWZU01000030_gene823	2.137e-07	58.0	COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,2U77T@28211|Alphaproteobacteria,3JZ71@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	Outer membrane transport energization protein ExbD	exbD	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS2_k127_7518397_12	1026882.MAMP_01033	6.246e-23	109.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,460KS@72273|Thiotrichales	72273|Thiotrichales	U	MotA TolQ ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS2_k127_7518397_20	1156937.MFUM_260033	4.637e-12	80.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,46T9I@74201|Verrucomicrobia,37GFA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS2_k127_7518397_28	867903.ThesuDRAFT_00041	1.956e-05	57.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM26,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
LZS2_k127_7518397_16	880073.Calab_2182	2.181e-15	89.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
LZS2_k127_7518397_25	1278073.MYSTI_06441	1.878e-06	62.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,438GF@68525|delta/epsilon subdivisions,2X3RA@28221|Deltaproteobacteria,2YWWZ@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial Ig-like domain (group 1)	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,LTD
LZS2_k127_7518397_11	880073.Calab_2082	3.989e-24	120.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
LZS2_k127_7518397_8	7070.TC009448-PA	1.594e-32	148.0	COG4870@1|root,KOG1543@2759|Eukaryota,38I5R@33154|Opisthokonta,3BF68@33208|Metazoa,3CWSV@33213|Bilateria,41WFX@6656|Arthropoda,3SJWJ@50557|Insecta	33208|Metazoa	O	Cysteine-type peptidase activity. It is involved in the biological process described with proteolysis	-	GO:0000003,GO:0000323,GO:0002376,GO:0003674,GO:0003824,GO:0004175,GO:0004177,GO:0004197,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0006508,GO:0006807,GO:0006915,GO:0006919,GO:0006955,GO:0008047,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008238,GO:0008656,GO:0009056,GO:0009057,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0016504,GO:0016505,GO:0016787,GO:0019222,GO:0019538,GO:0023051,GO:0023056,GO:0030162,GO:0030163,GO:0030234,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0032501,GO:0032504,GO:0042981,GO:0043028,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043280,GO:0043281,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051603,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0098772,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:2000116,GO:2001056,GO:2001233,GO:2001235	3.4.22.15,3.4.22.27,3.4.22.38	ko:K01365,ko:K01368,ko:K01371	ko04140,ko04142,ko04145,ko04210,ko04380,ko04612,ko04620,ko05152,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04380,map04612,map04620,map05152,map05205,map05323,map05418	-	-	-	ko00000,ko00001,ko00537,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I29,Peptidase_C1
LZS2_k127_7518397_9	1047013.AQSP01000139_gene2368	2.623e-32	134.0	COG0730@1|root,COG0730@2|Bacteria,2NRZN@2323|unclassified Bacteria	2|Bacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_7518397_17	373903.Hore_22330	1.029e-13	73.0	2DG7P@1|root,2ZUUE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7518397_10	13616.ENSMODP00000025779	2.086e-24	105.0	COG0529@1|root,KOG4238@2759|Eukaryota,38GMU@33154|Opisthokonta,3BDIX@33208|Metazoa,3CVIK@33213|Bilateria,485PB@7711|Chordata,493E8@7742|Vertebrata,3J2A4@40674|Mammalia,4K1TF@9263|Metatheria	33208|Metazoa	F	3'-phosphoadenosine 5'-phosphosulfate synthase 1	PAPSS1	GO:0000103,GO:0001501,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009336,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032501,GO:0032502,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034641,GO:0034654,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0046983,GO:0048731,GO:0048856,GO:0050427,GO:0050428,GO:0055086,GO:0061695,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
LZS2_k127_7518397_5	109760.SPPG_04254T0	1.918e-48	177.0	COG0529@1|root,KOG0635@2759|Eukaryota,39J77@33154|Opisthokonta,3NW9X@4751|Fungi	4751|Fungi	F	Catalyzes the synthesis of activated sulfate	MET14	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0055114,GO:0071704,GO:1901564	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YKL001C,iND750.YKL001C	APS_kinase
LZS2_k127_7518397_2	1167006.UWK_01677	1.092e-81	286.0	COG0477@1|root,COG2814@2|Bacteria,1QWMM@1224|Proteobacteria,42PZZ@68525|delta/epsilon subdivisions,2WJ1J@28221|Deltaproteobacteria,2MIYY@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
LZS2_k127_7518397_4	1114856.C496_19275	1.37e-54	202.0	arCOG14740@1|root,arCOG14740@2157|Archaea,2Y46U@28890|Euryarchaeota	28890|Euryarchaeota	S	TupA-like ATPgrasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_TupA
LZS2_k127_7518397_3	404380.Gbem_3444	1.822e-76	274.0	COG2006@1|root,COG2006@2|Bacteria,1NS70@1224|Proteobacteria,42Y7Z@68525|delta/epsilon subdivisions,2WTXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_7518397_27	1499685.CCFJ01000046_gene3047	1.569e-05	47.0	2AWWS@1|root,31NUA@2|Bacteria,1TZQC@1239|Firmicutes,4II4H@91061|Bacilli,1ZKNB@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7518397_26	1123073.KB899241_gene1839	8.218e-06	53.0	2ATJ5@1|root,31J35@2|Bacteria,1QGTA@1224|Proteobacteria,1TE8Y@1236|Gammaproteobacteria,1X946@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7518397_24	1379270.AUXF01000005_gene679	1.168e-06	60.0	2DUTE@1|root,33S5W@2|Bacteria,1ZSMI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7518397_1	702437.HMPREF9432_00784	6.167e-87	301.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4H2P5@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
LZS2_k127_7518397_15	313612.L8106_15749	7.652e-17	93.0	COG0457@1|root,COG4421@1|root,COG0457@2|Bacteria,COG4421@2|Bacteria,1G22H@1117|Cyanobacteria,1H8WY@1150|Oscillatoriales	1117|Cyanobacteria	G	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF563,TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_7,TPR_8
LZS2_k127_7518397_19	63737.Npun_R1867	1.87e-13	79.0	COG0457@1|root,COG0457@2|Bacteria,1G39E@1117|Cyanobacteria,1HQX3@1161|Nostocales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
LZS2_k127_7518397_29	28258.KP05_16800	3.085e-05	56.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,1RQZJ@1236|Gammaproteobacteria,1XJ8A@135619|Oceanospirillales	135619|Oceanospirillales	I	Long-chain fatty acid transport protein	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
LZS2_k127_7518397_18	1173027.Mic7113_5806	1.163e-13	77.0	COG0848@1|root,COG0848@2|Bacteria,1G71E@1117|Cyanobacteria,1HBT5@1150|Oscillatoriales	1117|Cyanobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS2_k127_7518397_6	880073.Calab_1219	2.489e-46	175.0	COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB2	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
LZS2_k127_7518397_13	880073.Calab_1220	2.255e-19	98.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	tonB3	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
LZS2_k127_7518397_7	1203606.HMPREF1526_00005	1.286e-40	162.0	COG0500@1|root,COG2226@2|Bacteria,1TR7I@1239|Firmicutes,24FG4@186801|Clostridia	186801|Clostridia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS2_k127_7518397_14	1156937.MFUM_70018	2.346e-18	90.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia,37GYP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
LZS2_k127_7518397_0	518766.Rmar_2194	1.104e-155	503.0	COG0160@1|root,COG0160@2|Bacteria,4NGPB@976|Bacteroidetes,1FITF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.36	ko:K03918	ko01100,map01100	-	R00457	RC00006,RC00062	ko00000,ko01000,ko01007	-	-	-	Aminotran_3
LZS2_k127_7576235_1	880073.Calab_3660	2.565e-62	231.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
LZS2_k127_7576235_0	1122927.KB895418_gene2740	1.977e-84	287.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,26S2E@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
LZS2_k127_7588879_5	1395513.P343_00530	1.945e-16	85.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,4HKA1@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_7588879_1	880073.Calab_1153	1.807e-102	349.0	COG0591@1|root,COG0591@2|Bacteria,2NRJT@2323|unclassified Bacteria	2|Bacteria	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS2_k127_7588879_3	688269.Theth_0209	1.482e-31	129.0	COG0394@1|root,COG0394@2|Bacteria,2GDH0@200918|Thermotogae	200918|Thermotogae	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS2_k127_7588879_2	517417.Cpar_1315	1.008e-53	207.0	COG1538@1|root,COG1538@2|Bacteria,1FE66@1090|Chlorobi	1090|Chlorobi	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS2_k127_7588879_4	1123278.KB893570_gene2461	4.854e-17	93.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,47MFI@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS2_k127_7588879_0	1499967.BAYZ01000028_gene1227	4.235e-171	567.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_7591987_2	237368.SCABRO_01223	1.478e-51	201.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
LZS2_k127_7591987_1	555088.DealDRAFT_0283	7.866e-84	291.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,42JHX@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
LZS2_k127_7591987_0	760568.Desku_1902	2.315e-92	308.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
LZS2_k127_7595538_1	880073.Calab_2683	3.712e-59	213.0	COG1007@1|root,COG1007@2|Bacteria,2NNMY@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS2_k127_7595538_3	1457250.BBMO01000001_gene1924	1.992e-05	49.0	arCOG02989@1|root,arCOG02989@2157|Archaea,2Y00B@28890|Euryarchaeota,23XHN@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1931
LZS2_k127_7595538_0	926569.ANT_11190	4.729e-98	324.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
LZS2_k127_7595538_2	459349.CLOAM0442	1.813e-26	111.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
LZS2_k127_7647261_2	56780.SYN_02059	1.041e-92	313.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MQHV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS2_k127_7647261_0	56780.SYN_02058	1.864e-149	491.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MSKF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
LZS2_k127_7647261_1	1408422.JHYF01000010_gene3332	1.416e-109	368.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,36DYZ@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
LZS2_k127_7647417_1	1499967.BAYZ01000123_gene2533	3.402e-33	142.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_7647417_0	340177.Cag_1863	2.329e-57	214.0	COG0438@1|root,COG0438@2|Bacteria,1FE7C@1090|Chlorobi	1090|Chlorobi	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
LZS2_k127_7647417_2	1047013.AQSP01000057_gene1924	3.525e-09	66.0	2A6YD@1|root,30VTC@2|Bacteria,2NQ0X@2323|unclassified Bacteria	2|Bacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
LZS2_k127_7667591_3	1047013.AQSP01000083_gene1194	1.432e-44	172.0	COG1994@1|root,COG1994@2|Bacteria,2NPQP@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	ywhC	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
LZS2_k127_7667591_4	1123511.KB905853_gene3721	1.128e-42	168.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4H3BM@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
LZS2_k127_7667591_5	1121468.AUBR01000032_gene1172	9.678e-32	130.0	COG2029@1|root,COG2029@2|Bacteria,1V5P0@1239|Firmicutes,24IRW@186801|Clostridia,42GR7@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF366)	-	-	-	ko:K09139	-	-	-	-	ko00000	-	-	-	DUF366
LZS2_k127_7667591_2	370438.PTH_1402	2.1e-47	178.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,261GZ@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
LZS2_k127_7667591_8	879310.HMPREF9162_1344	9.234e-22	99.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes	1239|Firmicutes	H	PFAM 6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
LZS2_k127_7667591_9	74547.PMT_1811	1.658e-16	92.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_11,TPR_16,TPR_2,TPR_8
LZS2_k127_7667591_7	523791.Kkor_1114	1.362e-22	101.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1XM5A@135619|Oceanospirillales	135619|Oceanospirillales	K	cold-shock protein	cspG	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS2_k127_7667591_6	1485545.JQLW01000006_gene295	3.997e-26	123.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria	1224|Proteobacteria	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
LZS2_k127_7667591_1	1131269.AQVV01000001_gene1314	2.631e-51	190.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
LZS2_k127_7667591_0	1379698.RBG1_1C00001G1613	7.85e-73	268.0	COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria	2|Bacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,PEGA,Pkinase
LZS2_k127_7667591_10	545264.KB898746_gene791	5.728e-11	68.0	COG0859@1|root,COG0859@2|Bacteria,1NG5A@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS2_k127_7670070_9	1255043.TVNIR_2912	8.351e-20	90.0	COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,1S2T5@1236|Gammaproteobacteria,1WYYI@135613|Chromatiales	135613|Chromatiales	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_7670070_6	1121920.AUAU01000006_gene301	2.876e-46	173.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7670070_10	869213.JCM21142_181	4.725e-19	93.0	2DBJC@1|root,2Z9K5@2|Bacteria,4P1C2@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolase family 47	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_47
LZS2_k127_7670070_0	929556.Solca_2801	5e-323	1012.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IPRD@117747|Sphingobacteriia	976|Bacteroidetes	G	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
LZS2_k127_7670070_5	313595.P700755_001844	2.565e-49	186.0	COG0454@1|root,COG0454@2|Bacteria,4PM9D@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
LZS2_k127_7670070_8	1121918.ARWE01000001_gene3574	2.369e-38	147.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,42U1P@68525|delta/epsilon subdivisions,2WQF3@28221|Deltaproteobacteria,43STN@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
LZS2_k127_7670070_4	1123508.JH636446_gene6211	6.545e-71	247.0	COG0177@1|root,COG0177@2|Bacteria,2IYYT@203682|Planctomycetes	203682|Planctomycetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
LZS2_k127_7670070_1	96561.Dole_1370	7.86e-177	566.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2MJ0H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS2_k127_7670070_3	96561.Dole_1371	1.349e-73	255.0	COG5002@1|root,COG5002@2|Bacteria,1R6WE@1224|Proteobacteria,42P99@68525|delta/epsilon subdivisions,2WK5E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11383	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8
LZS2_k127_7670070_2	554065.XP_005849456.1	8.076e-84	300.0	COG0616@1|root,2QQH5@2759|Eukaryota,37JSU@33090|Viridiplantae,34JKR@3041|Chlorophyta	3041|Chlorophyta	OU	protease IV	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS2_k127_7670070_7	1047013.AQSP01000128_gene444	9.792e-39	156.0	2CK1R@1|root,32V4M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7692793_14	368407.Memar_1765	3.692e-39	150.0	COG1047@1|root,arCOG00981@2157|Archaea,2XXFW@28890|Euryarchaeota,2NAZY@224756|Methanomicrobia	224756|Methanomicrobia	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
LZS2_k127_7692793_8	870187.Thini_2540	5.122e-133	436.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,460KI@72273|Thiotrichales	72273|Thiotrichales	P	Biological Process cation transport (GO 0006812), Molecular Function solute hydrogen antiporter activity (GO 0015299), Cellular Component integral to membrane (GO 0016021), Biological Process transmembrane transport (GO 0055085)	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
LZS2_k127_7692793_17	765952.PUV_11500	6.326e-34	138.0	2BSIE@1|root,314AF@2|Bacteria,2JGCI@204428|Chlamydiae	204428|Chlamydiae	S	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
LZS2_k127_7692793_2	1121920.AUAU01000007_gene506	5.536e-196	619.0	COG0477@1|root,COG2814@2|Bacteria,3Y6YQ@57723|Acidobacteria	57723|Acidobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS2_k127_7692793_13	1121468.AUBR01000038_gene1975	9.44e-62	230.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,42EV3@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
LZS2_k127_7692793_22	1231241.Mc24_01489	0.0005491	44.0	COG0820@1|root,COG0820@2|Bacteria,2GC4T@200918|Thermotogae	200918|Thermotogae	J	PFAM Radical SAM domain protein	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	-
LZS2_k127_7692793_6	489825.LYNGBM3L_61280	3.071e-136	446.0	COG2855@1|root,COG2855@2|Bacteria,1G0H4@1117|Cyanobacteria,1H7QS@1150|Oscillatoriales	1117|Cyanobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
LZS2_k127_7692793_7	96561.Dole_0304	2.364e-135	442.0	COG0823@1|root,COG0823@2|Bacteria,1MX4U@1224|Proteobacteria,42PEP@68525|delta/epsilon subdivisions,2WJUC@28221|Deltaproteobacteria,2MIWM@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	tmcD	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS2_k127_7692793_11	706587.Desti_5333	1.019e-67	236.0	COG2181@1|root,COG2181@2|Bacteria,1RERF@1224|Proteobacteria,42RXQ@68525|delta/epsilon subdivisions,2WN8Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
LZS2_k127_7692793_1	706587.Desti_5332	1.452e-211	664.0	COG0247@1|root,COG1150@1|root,COG0247@2|Bacteria,COG1150@2|Bacteria,1MUMH@1224|Proteobacteria,42N9U@68525|delta/epsilon subdivisions,2WINY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	tmcB	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
LZS2_k127_7692793_5	1121405.dsmv_0146	1.748e-139	461.0	COG0484@1|root,COG0484@2|Bacteria,1R72H@1224|Proteobacteria,42NCE@68525|delta/epsilon subdivisions,2WKDN@28221|Deltaproteobacteria,2MKP5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
LZS2_k127_7692793_4	485915.Dret_0876	6.139e-140	453.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2M9HU@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	hmcB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
LZS2_k127_7692793_3	1304885.AUEY01000001_gene3189	1.091e-175	558.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42P2Q@68525|delta/epsilon subdivisions,2WKC2@28221|Deltaproteobacteria,2MJCP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	hmcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	NrfD
LZS2_k127_7692793_18	706587.Desti_5336	3.856e-31	127.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_7692793_9	706587.Desti_4208	3.139e-73	267.0	COG3852@1|root,COG5000@1|root,COG3852@2|Bacteria,COG5000@2|Bacteria,1R1JU@1224|Proteobacteria,43DA4@68525|delta/epsilon subdivisions,2X8GR@28221|Deltaproteobacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	regM	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
LZS2_k127_7692793_20	706587.Desti_0283	2.766e-22	104.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_7692793_19	706587.Desti_5336	2.108e-30	124.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_7692793_12	693661.Arcve_1696	6.699e-66	237.0	COG2181@1|root,arCOG02196@2157|Archaea	2157|Archaea	C	PFAM Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
LZS2_k127_7692793_0	693661.Arcve_1697	6.289e-216	682.0	COG0247@1|root,arCOG00333@2157|Archaea	2157|Archaea	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K18501	-	-	-	-	ko00000	-	-	-	CCG,Fer4_8
LZS2_k127_7692793_15	1485545.JQLW01000009_gene154	4.726e-37	156.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria	1224|Proteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_1375,iECSF_1327.ECSF_1186,iUTI89_1310.UTI89_C1404	GlutR_N,GlutR_dimer,Shikimate_DH
LZS2_k127_7692793_16	1122176.KB903531_gene3072	2.419e-34	143.0	COG0642@1|root,COG2205@2|Bacteria,4NK58@976|Bacteroidetes,1IPNM@117747|Sphingobacteriia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS2_k127_7692793_10	649638.Trad_0223	1.387e-69	244.0	COG0745@1|root,COG0745@2|Bacteria,1WM7Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS2_k127_770621_1	1123037.AUDE01000022_gene1493	3.453e-07	61.0	COG2244@1|root,COG2244@2|Bacteria,4NGVA@976|Bacteroidetes,1IJ0M@117743|Flavobacteriia	976|Bacteroidetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS2_k127_770621_0	247490.KSU1_C1548	2.411e-118	400.0	COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes	203682|Planctomycetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
LZS2_k127_7722055_2	933262.AXAM01000016_gene190	1.145e-76	262.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2MI4N@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_7722055_1	933262.AXAM01000016_gene189	8.042e-91	306.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2MIHA@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
LZS2_k127_7722055_0	1047013.AQSP01000113_gene743	1.218e-225	729.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
LZS2_k127_7722055_3	1047013.AQSP01000113_gene742	1.598e-67	241.0	28V7D@1|root,2ZHAI@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
LZS2_k127_7736312_0	1379698.RBG1_1C00001G1367	9.747e-44	165.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_7804194_0	1379698.RBG1_1C00001G1061	1.394e-125	410.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
LZS2_k127_7804194_1	243231.GSU0351	3.93e-111	377.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS2_k127_7813846_1	1237149.C900_01169	9.073e-131	428.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,47JQ6@768503|Cytophagia	976|Bacteroidetes	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
LZS2_k127_7813846_8	1124780.ANNU01000017_gene1934	0.0001358	49.0	COG2120@1|root,COG2120@2|Bacteria,4NMM2@976|Bacteroidetes,47WAX@768503|Cytophagia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS2_k127_7813846_4	491915.Aflv_0876	3.475e-93	311.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,21V6K@150247|Anoxybacillus	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
LZS2_k127_7813846_3	945713.IALB_0230	3.165e-129	428.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	hemG	-	1.14.19.9,1.3.3.15,1.3.3.4	ko:K00231,ko:K14266	ko00404,ko00860,ko01100,ko01110,ko01130,map00404,map00860,map01100,map01110,map01130	M00121,M00789,M00790	R03222,R04178,R09570	RC00885,RC00949	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09325	Amino_oxidase
LZS2_k127_7813846_5	1191523.MROS_0607	1.508e-81	282.0	COG0276@1|root,COG0276@2|Bacteria	2|Bacteria	H	ferrochelatase activity	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1540,iECS88_1305.ECS88_0472,iEcE24377_1341.EcE24377A_0515	Ferrochelatase
LZS2_k127_7813846_0	292415.Tbd_0635	3.387e-155	503.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,1KRH5@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
LZS2_k127_7813846_2	945713.IALB_0539	2.75e-130	424.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3734,iSBO_1134.SBO_4018	URO-D
LZS2_k127_7813846_6	1163409.UUA_16398	9.231e-45	166.0	COG0454@1|root,COG0456@2|Bacteria,1RJ1K@1224|Proteobacteria,1S6RV@1236|Gammaproteobacteria,1X6U1@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS2_k127_7813846_7	573370.DMR_06800	2.068e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2M91R@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
LZS2_k127_7891684_3	247490.KSU1_B0631	4.297e-24	114.0	COG0265@1|root,COG0265@2|Bacteria,2IY5I@203682|Planctomycetes	203682|Planctomycetes	O	PDZ domain (Also known as DHR	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS2_k127_7891684_5	1304883.KI912532_gene2918	3.662e-09	60.0	COG0367@1|root,COG0367@2|Bacteria,1PRFK@1224|Proteobacteria,2VJKQ@28216|Betaproteobacteria,2KV2F@206389|Rhodocyclales	206389|Rhodocyclales	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS2_k127_7891684_1	395495.Lcho_3085	1.098e-60	225.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2VMU1@28216|Betaproteobacteria,1KMEA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	PFAM Glycosyl transferases group 1	epsN	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_7891684_4	1348114.OM33_15960	3.498e-12	79.0	COG3307@1|root,COG3307@2|Bacteria,1RBK5@1224|Proteobacteria,1S2Y8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS2_k127_7891684_2	880073.Calab_0612	2.963e-40	164.0	COG3206@1|root,COG3206@2|Bacteria,2NQ0K@2323|unclassified Bacteria	2|Bacteria	M	Chain length determinant protein	-	-	3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1	-	-	GNVR,Wzz
LZS2_k127_7891684_0	1121481.AUAS01000005_gene1995	5.15e-75	267.0	COG1215@1|root,COG1215@2|Bacteria,4NEG0@976|Bacteroidetes,47KET@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS2_k127_7891684_6	1384054.N790_11490	9.29e-09	68.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,1X5VS@135614|Xanthomonadales	135614|Xanthomonadales	T	two-component system sensor-response regulator hybrid protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
LZS2_k127_7933531_4	861299.J421_1911	1.251e-30	122.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS2_k127_7933531_1	926692.AZYG01000085_gene806	3.943e-130	428.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3WBI1@53433|Halanaerobiales	186801|Clostridia	S	PFAM HI0933 family protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
LZS2_k127_7933531_3	1267534.KB906754_gene3807	4.234e-65	248.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	7TMR-DISM_7TM,HAMP,Peripla_BP_3,SpoIIE
LZS2_k127_7933531_2	396588.Tgr7_1190	4.259e-117	383.0	COG1432@1|root,COG1432@2|Bacteria,1PQBD@1224|Proteobacteria,1T9WF@1236|Gammaproteobacteria,1X1QQ@135613|Chromatiales	135613|Chromatiales	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
LZS2_k127_7933531_0	1163617.SCD_n00025	1.491e-160	515.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria	1224|Proteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_7960377_0	880073.Calab_0065	5.154e-197	641.0	COG0249@1|root,COG0249@2|Bacteria,2NNN6@2323|unclassified Bacteria	2|Bacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
LZS2_k127_7960377_16	1379698.RBG1_1C00001G0158	9.831e-10	72.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
LZS2_k127_7960377_1	1379698.RBG1_1C00001G1139	3.265e-122	416.0	COG0323@1|root,COG0323@2|Bacteria,2NNP7@2323|unclassified Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
LZS2_k127_7960377_10	585530.HMPREF0183_1110	3.255e-54	205.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4F92W@85019|Brevibacteriaceae	201174|Actinobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
LZS2_k127_7960377_19	485916.Dtox_3982	4.902e-06	57.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,Big_3_2,Cadherin-like,DUF4347,He_PIG,HemolysinCabind,Laminin_G_3,SLH
LZS2_k127_7960377_4	429009.Adeg_1225	6.831e-82	289.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,42EX0@68295|Thermoanaerobacterales	186801|Clostridia	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
LZS2_k127_7960377_2	479434.Sthe_1284	3.915e-115	385.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi,27XGH@189775|Thermomicrobia	189775|Thermomicrobia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	-	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
LZS2_k127_7960377_12	1403819.BATR01000094_gene2952	8.496e-45	170.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,2IUDC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Glycerol-3-phosphate acyltransferase	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
LZS2_k127_7960377_3	857293.CAAU_1295	9.044e-105	351.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,36EG4@31979|Clostridiaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
LZS2_k127_7960377_14	1379698.RBG1_1C00001G1177	4.898e-26	111.0	COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	ko:K19591,ko:K22491	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR_1
LZS2_k127_7960377_15	247490.KSU1_C1386	2.447e-22	108.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K20543,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	1.B.55.3	-	-	Lip_A_acyltrans,TPR_19
LZS2_k127_7960377_11	1379698.RBG1_1C00001G1176	2.389e-49	184.0	COG1216@1|root,COG1216@2|Bacteria,2NS4X@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase family 2	XK27_08075	-	-	-	-	-	-	-	-	-	-	-	DUF2062,Glycos_transf_2,GtrA,Lip_A_acyltrans
LZS2_k127_7960377_6	289376.THEYE_A1499	2.759e-61	221.0	COG0496@1|root,COG0496@2|Bacteria,3J0IG@40117|Nitrospirae	40117|Nitrospirae	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
LZS2_k127_7960377_8	667014.Thein_1148	1.017e-55	202.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS2_k127_7960377_13	1094980.Mpsy_1210	1.824e-36	145.0	COG2426@1|root,arCOG01330@2157|Archaea,2XZ2Y@28890|Euryarchaeota,2NAQX@224756|Methanomicrobia	224756|Methanomicrobia	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
LZS2_k127_7960377_21	1122226.AUHX01000001_gene895	0.0001275	48.0	2EMJ4@1|root,33F7P@2|Bacteria,4NYXT@976|Bacteroidetes,1I5IS@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7960377_5	867903.ThesuDRAFT_00741	6.531e-63	228.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WCCM@538999|Clostridiales incertae sedis	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS2_k127_7960377_7	96561.Dole_2619	6.69e-58	206.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,2MJM5@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
LZS2_k127_7960377_9	1047013.AQSP01000109_gene2428	3.048e-55	211.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
LZS2_k127_7960377_20	1210884.HG799466_gene12912	6.514e-06	53.0	2E7TZ@1|root,33290@2|Bacteria,2J410@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_7981024_8	1123284.KB899043_gene249	2.483e-22	98.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,26NAA@186821|Sporolactobacillaceae	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
LZS2_k127_7981024_4	335543.Sfum_1414	9.473e-96	325.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS2_k127_7981024_5	1123376.AUIU01000014_gene532	2.136e-92	313.0	COG0601@1|root,COG0601@2|Bacteria,3J12R@40117|Nitrospirae	40117|Nitrospirae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS2_k127_7981024_1	335543.Sfum_1411	9.833e-128	430.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2MQ6I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
LZS2_k127_7981024_6	529818.AMSG_09105T0	1.42e-26	122.0	COG2234@1|root,KOG2195@2759|Eukaryota	2759|Eukaryota	L	exopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS2_k127_7981024_0	177437.HRM2_07790	3.861e-140	465.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,2MJA8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS2_k127_7981024_9	449447.MAE_46550	3.085e-09	63.0	COG2165@1|root,COG2165@2|Bacteria,1G7YC@1117|Cyanobacteria	1117|Cyanobacteria	NU	PFAM Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_GH
LZS2_k127_7981024_10	682795.AciX8_1786	1.012e-08	63.0	COG2165@1|root,COG2165@2|Bacteria,3Y4ZX@57723|Acidobacteria,2JJN5@204432|Acidobacteriia	204432|Acidobacteriia	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
LZS2_k127_7981024_3	880073.Calab_1323	1.897e-118	387.0	COG0330@1|root,COG0330@2|Bacteria,2NP2X@2323|unclassified Bacteria	2|Bacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
LZS2_k127_7981024_2	880073.Calab_1322	3.205e-120	395.0	COG0330@1|root,COG0330@2|Bacteria,2NP3W@2323|unclassified Bacteria	2|Bacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
LZS2_k127_7981024_7	247490.KSU1_C0780	1.602e-23	117.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	ko:K07289,ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA,AsmA_1,AsmA_2,DUF3971,DctA-YdbH
LZS2_k127_7987111_1	665571.STHERM_c02830	6.215e-90	298.0	COG0174@1|root,COG0174@2|Bacteria,2J6JS@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
LZS2_k127_7987111_0	1232410.KI421413_gene501	2.071e-120	419.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
LZS2_k127_7987111_4	235985.BBPN01000010_gene4384	7.899e-80	300.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,2NEN3@228398|Streptacidiphilus	201174|Actinobacteria	OT	Glutamate-ammonia ligase adenylyltransferase	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
LZS2_k127_7987111_5	648996.Theam_0628	6.92e-47	170.0	COG0347@1|root,COG0347@2|Bacteria,2G43N@200783|Aquificae	200783|Aquificae	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
LZS2_k127_7987111_3	396588.Tgr7_3016	8.521e-86	297.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1WWRX@135613|Chromatiales	135613|Chromatiales	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
LZS2_k127_7987111_2	273068.TTE1717	7.472e-86	295.0	COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,42FF0@68295|Thermoanaerobacterales	186801|Clostridia	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS2_k127_7987111_6	1458462.JNLK01000001_gene1165	0.0004016	49.0	COG0642@1|root,COG2205@2|Bacteria,1UZ8S@1239|Firmicutes,25BJP@186801|Clostridia,27PAN@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS2_k127_8006502_6	264462.Bd2801	2.966e-26	111.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2MU0J@213481|Bdellovibrionales,2WQYK@28221|Deltaproteobacteria	213481|Bdellovibrionales	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
LZS2_k127_8006502_0	379066.GAU_1219	4.85e-107	355.0	COG0462@1|root,COG0462@2|Bacteria,1ZT7Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
LZS2_k127_8006502_4	926561.KB900617_gene2256	2.682e-39	155.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3WBPT@53433|Halanaerobiales	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
LZS2_k127_8006502_2	517417.Cpar_1258	1.8e-45	171.0	COG0193@1|root,COG0193@2|Bacteria,1FES3@1090|Chlorobi	1090|Chlorobi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
LZS2_k127_8006502_7	748727.CLJU_c42790	5.622e-22	100.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,36JK5@31979|Clostridiaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
LZS2_k127_8006502_8	1408437.JNJN01000012_gene315	6.835e-21	94.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,25WV7@186806|Eubacteriaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
LZS2_k127_8006502_3	880073.Calab_2408	5.498e-44	165.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
LZS2_k127_8006502_1	1191523.MROS_0017	1.236e-91	313.0	COG0836@1|root,COG0836@2|Bacteria	2|Bacteria	M	mannose-1-phosphate guanylyltransferase activity	manC	-	2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00940	MannoseP_isomer,NTP_transferase
LZS2_k127_8006502_9	1347369.CCAD010000013_gene2543	5.463e-13	81.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,4IQKZ@91061|Bacilli,1ZRKZ@1386|Bacillus	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
LZS2_k127_8006502_10	1122176.KB903554_gene3803	2.319e-05	56.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	LysM,TPR_16,TPR_6,YfiO
LZS2_k127_8006502_5	439235.Dalk_2411	5.403e-34	136.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2MJT1@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
LZS2_k127_8043710_7	1499967.BAYZ01000061_gene5954	4.485e-37	158.0	COG1533@1|root,COG1533@2|Bacteria,2NPZ9@2323|unclassified Bacteria	2|Bacteria	L	DNA photolyase activity	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
LZS2_k127_8043710_4	868864.Dester_0185	4.698e-67	237.0	COG0705@1|root,COG0705@2|Bacteria,2G438@200783|Aquificae	200783|Aquificae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS2_k127_8043710_9	324602.Caur_1299	7.82e-25	117.0	COG3222@1|root,COG3222@2|Bacteria,2G988@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
LZS2_k127_8043710_5	1244531.CIG1485E_0172	3.346e-65	230.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2YMUT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
LZS2_k127_8043710_8	1131269.AQVV01000018_gene1932	1.079e-30	128.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
LZS2_k127_8043710_1	653733.Selin_0888	2.159e-145	476.0	COG0649@1|root,COG0649@2|Bacteria	2|Bacteria	C	NAD binding	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
LZS2_k127_8043710_6	760154.Sulba_0412	3.183e-42	160.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SRI@68525|delta/epsilon subdivisions,2YQ7X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH-quinone oxidoreductase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
LZS2_k127_8043710_0	653733.Selin_0886	8.975e-170	548.0	COG1894@1|root,COG1894@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
LZS2_k127_8043710_3	118005.AWNK01000006_gene1205	1.17e-101	357.0	COG1034@1|root,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
LZS2_k127_8043710_2	118005.AWNK01000006_gene1206	7.544e-115	383.0	COG1005@1|root,COG1005@2|Bacteria	2|Bacteria	C	quinone binding	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS2_k127_8093327_1	243090.RB5098	8.214e-71	243.0	COG1045@1|root,COG1045@2|Bacteria,2IX5K@203682|Planctomycetes	203682|Planctomycetes	E	COG1045 Serine acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
LZS2_k127_8093327_7	379066.GAU_2794	1.666e-05	58.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
LZS2_k127_8093327_0	226186.BT_2374	2.685e-106	372.0	COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,2FPYJ@200643|Bacteroidia,4APBK@815|Bacteroidaceae	976|Bacteroidetes	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
LZS2_k127_8093327_8	1121374.KB891576_gene686	0.0008048	52.0	COG2304@1|root,COG2304@2|Bacteria,1NBG1@1224|Proteobacteria	1224|Proteobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8093327_4	880073.Calab_0648	1.632e-15	91.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
LZS2_k127_8093327_3	1131462.DCF50_p1620	7.804e-21	105.0	COG0265@1|root,COG0265@2|Bacteria,1TRQS@1239|Firmicutes,24E3C@186801|Clostridia,260WW@186807|Peptococcaceae	186801|Clostridia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S7,Trypsin
LZS2_k127_8093327_6	644281.MFS40622_0774	1.252e-08	59.0	arCOG13418@1|root,arCOG13418@2157|Archaea,2Y5VK@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8093327_2	686340.Metal_3843	2.586e-68	250.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,1T460@1236|Gammaproteobacteria,1XEF0@135618|Methylococcales	135618|Methylococcales	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8100682_5	1449350.OCH239_04425	6.735e-06	53.0	COG0500@1|root,COG2890@1|root,COG2226@2|Bacteria,COG2890@2|Bacteria,1R5JA@1224|Proteobacteria,2TXTJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS2_k127_8100682_1	331678.Cphamn1_0104	5.448e-83	277.0	COG2406@1|root,COG2406@2|Bacteria,1FE1U@1090|Chlorobi	1090|Chlorobi	S	PFAM Ferritin, Dps family protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
LZS2_k127_8100682_4	550540.Fbal_2154	1.015e-23	103.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	endonuclease containing a URI domain	yhbQ	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
LZS2_k127_8100682_3	1131462.DCF50_p1700	2.424e-24	110.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24P0N@186801|Clostridia,2632C@186807|Peptococcaceae	186801|Clostridia	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
LZS2_k127_8100682_2	1298858.AUEL01000011_gene5538	5.181e-50	186.0	COG0500@1|root,COG2226@2|Bacteria,1REUM@1224|Proteobacteria,2U75Q@28211|Alphaproteobacteria,43JP9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Putative methyltransferase	btaB	-	-	ko:K13623	ko00564,map00564	-	R09073	RC00003,RC02308	ko00000,ko00001	-	-	-	Methyltransf_23,Methyltransf_25
LZS2_k127_8100682_0	1499967.BAYZ01000038_gene2261	1.011e-103	340.0	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS2_k127_814630_2	742740.HMPREF9474_02562	6.062e-31	121.0	2AU0F@1|root,31JKB@2|Bacteria,1V6XX@1239|Firmicutes,24KKM@186801|Clostridia,220GB@1506553|Lachnoclostridium	186801|Clostridia	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_814630_4	449673.BACSTE_03846	2.436e-06	52.0	2AHEJ@1|root,317RR@2|Bacteria,4P93N@976|Bacteroidetes,2FZC5@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_814630_0	1449126.JQKL01000008_gene293	4.571e-195	623.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,267RV@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
LZS2_k127_814630_1	1121405.dsmv_0379	9.915e-54	193.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
LZS2_k127_8154230_5	1382358.JHVN01000001_gene1078	1.031e-06	61.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4IQJY@91061|Bacilli,21XD6@150247|Anoxybacillus	1239|Firmicutes	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
LZS2_k127_8154230_3	1379698.RBG1_1C00001G0634	1.758e-46	173.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
LZS2_k127_8154230_2	1144275.COCOR_04873	1.412e-52	209.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
LZS2_k127_8154230_0	648996.Theam_0349	7.673e-88	301.0	COG0136@1|root,COG0136@2|Bacteria,2G3QW@200783|Aquificae	200783|Aquificae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS2_k127_8154230_6	1334046.AYTB01000008_gene2367	1.084e-05	56.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,26DDD@186818|Planococcaceae	91061|Bacilli	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
LZS2_k127_8154230_1	555079.Toce_0152	4.463e-63	224.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,42FMH@68295|Thermoanaerobacterales	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
LZS2_k127_8154230_4	1408422.JHYF01000012_gene3213	1.35e-21	95.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,36EK7@31979|Clostridiaceae	186801|Clostridia	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
LZS2_k127_8181093_4	768671.ThimaDRAFT_3982	1.052e-91	312.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1WZ19@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
LZS2_k127_8181093_1	926550.CLDAP_29660	8.205e-142	460.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
LZS2_k127_8181093_3	1121447.JONL01000004_gene2931	8.683e-115	377.0	COG0730@1|root,COG0730@2|Bacteria,1PYDH@1224|Proteobacteria,42P28@68525|delta/epsilon subdivisions,2WK6D@28221|Deltaproteobacteria,2M87J@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS2_k127_8181093_5	675812.VHA_001467	5.449e-48	175.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,1SH2H@1236|Gammaproteobacteria,1XXXJ@135623|Vibrionales	135623|Vibrionales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
LZS2_k127_8181093_2	1121920.AUAU01000018_gene1800	3.56e-129	428.0	COG0436@1|root,COG0436@2|Bacteria,3Y5C9@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS2_k127_8181093_0	1121405.dsmv_1573	4.035e-214	681.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MIKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
LZS2_k127_8181093_6	935567.JAES01000016_gene1510	7.512e-08	55.0	COG2095@1|root,COG2095@2|Bacteria,1N689@1224|Proteobacteria,1RPV0@1236|Gammaproteobacteria,1X4BK@135614|Xanthomonadales	135614|Xanthomonadales	U	UPF0056 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	MarC
LZS2_k127_8192244_0	997884.HMPREF1068_00362	3.907e-116	421.0	COG1361@1|root,COG1520@1|root,COG4870@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia,4ATRZ@815|Bacteroidaceae	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
LZS2_k127_8192244_2	42256.RradSPS_1688	1.281e-29	135.0	COG1807@1|root,COG1807@2|Bacteria,2GNPY@201174|Actinobacteria	201174|Actinobacteria	M	capsule polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8192244_1	1211115.ALIQ01000032_gene1979	3.984e-69	249.0	COG3118@1|root,COG3118@2|Bacteria,1QTZ9@1224|Proteobacteria,2TYBF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
LZS2_k127_8200036_5	644282.Deba_0361	4.506e-07	60.0	2CG1Y@1|root,32WID@2|Bacteria,1N01A@1224|Proteobacteria,42UK0@68525|delta/epsilon subdivisions,2WQED@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573,PapD-like
LZS2_k127_8200036_2	906968.Trebr_1593	7.213e-34	141.0	COG0847@1|root,COG0847@2|Bacteria,2J80N@203691|Spirochaetes	203691|Spirochaetes	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
LZS2_k127_8200036_1	1396418.BATQ01000113_gene4691	7.138e-50	190.0	COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS2_k127_8200036_0	518766.Rmar_0611	2.168e-62	224.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS2_k127_8200036_3	518766.Rmar_0610	2.283e-21	95.0	COG3034@1|root,COG3034@2|Bacteria,4NU5W@976|Bacteroidetes	976|Bacteroidetes	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS2_k127_8222107_5	401526.TcarDRAFT_1408	9.57e-48	179.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4H1VY@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS2_k127_8222107_1	1379698.RBG1_1C00001G1326	3.844e-159	508.0	COG2006@1|root,COG2006@2|Bacteria,2NPTK@2323|unclassified Bacteria	2|Bacteria	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
LZS2_k127_8222107_4	1499967.BAYZ01000193_gene3921	6.349e-73	255.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
LZS2_k127_8222107_6	1128111.HMPREF0870_00657	3.486e-46	173.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes,4H4BA@909932|Negativicutes	909932|Negativicutes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
LZS2_k127_8222107_3	1047013.AQSP01000144_gene874	4.826e-133	432.0	COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria	2|Bacteria	M	Nucleotidyl transferase	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS2_k127_8222107_7	443143.GM18_1429	1.011e-41	172.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42M62@68525|delta/epsilon subdivisions,2WJ83@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Polysaccharide export protein	-	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
LZS2_k127_8222107_0	667014.Thein_2079	1.063e-224	726.0	COG0013@1|root,COG0013@2|Bacteria,2GH36@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS2_k127_8222107_10	717605.Theco_2025	4.794e-10	68.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HM0B@91061|Bacilli,26U1A@186822|Paenibacillaceae	91061|Bacilli	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
LZS2_k127_8222107_2	278963.ATWD01000001_gene2099	2.122e-144	469.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
LZS2_k127_8222107_8	580340.Tlie_0852	1.649e-28	121.0	COG1514@1|root,COG1514@2|Bacteria,3TBEC@508458|Synergistetes	508458|Synergistetes	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
LZS2_k127_8222107_9	362976.HQ_1238A	1.802e-10	63.0	COG1546@1|root,arCOG04589@2157|Archaea,2XUK6@28890|Euryarchaeota,23UF0@183963|Halobacteria	183963|Halobacteria	S	protein (competence- and mitomycin-induced)	cinA3	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
LZS2_k127_8294504_2	267608.RSp0820	1.062e-18	94.0	COG2706@1|root,COG3391@1|root,COG2706@2|Bacteria,COG3391@2|Bacteria,1RB38@1224|Proteobacteria,2VSAM@28216|Betaproteobacteria,1KHW5@119060|Burkholderiaceae	28216|Betaproteobacteria	G	3-carboxymuconate cyclase quinoprotein amine dehydrogenase, beta chain-like	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
LZS2_k127_8294504_1	1123393.KB891316_gene1611	3.832e-58	212.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,1KSVU@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
LZS2_k127_8294504_0	1123393.KB891316_gene1612	2.538e-214	696.0	COG3637@1|root,COG5338@1|root,COG3637@2|Bacteria,COG5338@2|Bacteria,1PFWT@1224|Proteobacteria	1224|Proteobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2,OMP_b-brl
LZS2_k127_8304229_0	264732.Moth_1132	1.246e-140	463.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
LZS2_k127_8304229_4	1267535.KB906767_gene3589	0.0001917	53.0	COG2385@1|root,COG2385@2|Bacteria,3Y370@57723|Acidobacteria,2JM3F@204432|Acidobacteriia	204432|Acidobacteriia	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
LZS2_k127_8304229_1	1123373.ATXI01000008_gene1648	2.388e-107	362.0	COG0059@1|root,COG0059@2|Bacteria,2GH4M@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
LZS2_k127_8304229_2	1089553.Tph_c26820	4.982e-56	213.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,42F58@68295|Thermoanaerobacterales	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
LZS2_k127_8307656_4	880073.Calab_1286	1.78e-29	138.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
LZS2_k127_8307656_0	518766.Rmar_2753	2.646e-93	316.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1FIKZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
LZS2_k127_8307656_1	237368.SCABRO_00403	3.021e-84	294.0	COG2377@1|root,COG2377@2|Bacteria,2IZ2P@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
LZS2_k127_8307656_2	1379698.RBG1_1C00001G0322	9.072e-57	214.0	COG2385@1|root,COG2385@2|Bacteria,2NPRR@2323|unclassified Bacteria	2|Bacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
LZS2_k127_8307656_3	1499968.TCA2_3907	6.623e-51	201.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
LZS2_k127_8410025_5	477974.Daud_1728	8.676e-37	146.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG3605@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
LZS2_k127_8410025_2	644282.Deba_2013	2.15e-76	276.0	COG0745@1|root,COG2203@1|root,COG2206@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
LZS2_k127_8410025_1	667014.Thein_0626	3.472e-133	459.0	COG0612@1|root,COG0612@2|Bacteria,2GH66@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS2_k127_8410025_3	880073.Calab_1372	1.213e-71	250.0	COG1624@1|root,COG1624@2|Bacteria,2NPQS@2323|unclassified Bacteria	2|Bacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N,YojJ
LZS2_k127_8410025_4	1286106.MPL1_09065	2.418e-70	249.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,46031@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
LZS2_k127_8410025_0	1191523.MROS_0436	5.776e-200	632.0	COG0465@1|root,COG0465@2|Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS2_k127_8417011_3	869210.Marky_1666	1.419e-40	169.0	COG0438@1|root,COG2244@1|root,COG0438@2|Bacteria,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS2_k127_8417011_5	298654.FraEuI1c_0132	5.98e-36	149.0	COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria,4EUBX@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
LZS2_k127_8417011_1	5759.rna_EHI_111610-1	7.523e-111	375.0	COG3033@1|root,2QU0C@2759|Eukaryota,3X8H9@554915|Amoebozoa	554915|Amoebozoa	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS2_k127_8417011_0	485913.Krac_3042	4.409e-278	869.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
LZS2_k127_8417011_4	1185876.BN8_02959	1.783e-38	157.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF4440,SnoaL_2,SnoaL_3,YkuD
LZS2_k127_8417011_2	880073.Calab_1414	4.69e-102	339.0	COG0388@1|root,COG0388@2|Bacteria,2NPKU@2323|unclassified Bacteria	2|Bacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
LZS2_k127_8443144_3	1345695.CLSA_c20640	4.584e-09	62.0	COG2893@1|root,COG2893@2|Bacteria,1VB2D@1239|Firmicutes,24JJ1@186801|Clostridia,36N3B@31979|Clostridiaceae	186801|Clostridia	G	TIGRFAM PTS system, mannose fructose sorbose family, IIA	-	-	2.7.1.191	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
LZS2_k127_8443144_0	1379698.RBG1_1C00001G0555	1.771e-36	143.0	COG3444@1|root,COG3444@2|Bacteria,2NQ0P@2323|unclassified Bacteria	2|Bacteria	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794,ko:K19507	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276,M00764	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.19	-	-	PTSIIB_sorb
LZS2_k127_8443144_1	290397.Adeh_0151	1.261e-12	72.0	COG3716@1|root,COG3716@2|Bacteria,1P02J@1224|Proteobacteria,42RPH@68525|delta/epsilon subdivisions,2WNQI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system mannose fructose sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
LZS2_k127_8562072_3	314262.MED193_06354	1.487e-08	59.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,2UM3F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
LZS2_k127_8562072_4	269084.syc0681_c	1.064e-05	59.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1G0VR@1117|Cyanobacteria,1GZQK@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	ko:K06596,ko:K11526	ko02020,ko02025,map02020,map02025	M00507,M00508	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
LZS2_k127_8562072_1	56780.SYN_00478	4.9e-70	246.0	COG0388@1|root,COG0388@2|Bacteria,1MX4I@1224|Proteobacteria,42N4T@68525|delta/epsilon subdivisions,2WJK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
LZS2_k127_8562072_5	247490.KSU1_A0080	0.0004205	51.0	2DWWN@1|root,32V2B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8562072_2	857293.CAAU_0054	5.587e-17	91.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,24HZH@186801|Clostridia,36G4R@31979|Clostridiaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
LZS2_k127_8562072_0	580327.Tthe_2116	4.638e-195	619.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,42EYV@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
LZS2_k127_8563534_1	313628.LNTAR_20803	4.912e-15	77.0	COG0853@1|root,COG0853@2|Bacteria	2|Bacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
LZS2_k127_8563534_2	888055.HMPREF9015_01825	6.735e-09	68.0	COG4775@1|root,COG4775@2|Bacteria,378TB@32066|Fusobacteria	32066|Fusobacteria	M	Outer membrane protein, OMP85 family	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS2_k127_8563534_0	706587.Desti_0516	2.063e-42	163.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2MQBE@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS2_k127_8564691_11	546271.Selsp_0363	7.652e-38	150.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes	909932|Negativicutes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
LZS2_k127_8564691_3	945713.IALB_2642	4.612e-139	453.0	COG0172@1|root,COG0172@2|Bacteria	2|Bacteria	J	seryl-tRNA aminoacylation	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
LZS2_k127_8564691_7	1379698.RBG1_1C00001G1544	1.888e-88	307.0	COG4191@1|root,COG4191@2|Bacteria,2NPC5@2323|unclassified Bacteria	2|Bacteria	T	Integral membrane sensor signal transduction histidine kinase	vicK	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07709,ko:K13924	ko02020,ko02030,map02020,map02030	M00499,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
LZS2_k127_8564691_1	1379698.RBG1_1C00001G1545	5.498e-173	556.0	COG0745@1|root,COG0745@2|Bacteria,2NNXK@2323|unclassified Bacteria	2|Bacteria	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
LZS2_k127_8564691_16	243164.DET0396	3.571e-25	111.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,34CZN@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
LZS2_k127_8564691_18	269799.Gmet_1258	1.355e-21	104.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,43UMP@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
LZS2_k127_8564691_13	1121428.DESHY_160203___1	7.44e-31	127.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,26220@186807|Peptococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS2_k127_8564691_14	1379270.AUXF01000003_gene3573	6.691e-29	127.0	COG0005@1|root,COG0005@2|Bacteria,1ZTGZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS2_k127_8564691_4	880073.Calab_0770	2.769e-105	350.0	COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria	2|Bacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Carboxyl_trans
LZS2_k127_8564691_9	518766.Rmar_2308	7.51e-57	215.0	COG0285@1|root,COG0285@2|Bacteria,4NES8@976|Bacteroidetes,1FJ13@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS2_k127_8564691_10	1449126.JQKL01000070_gene3530	1.307e-56	214.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
LZS2_k127_8564691_5	1379698.RBG1_1C00001G0864	7.999e-101	367.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744,ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA,OstA_C
LZS2_k127_8564691_17	701521.PECL_908	7.049e-25	106.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,3F6YN@33958|Lactobacillaceae	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS2_k127_8564691_12	1131269.AQVV01000002_gene1187	4.983e-37	155.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	mnuA	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
LZS2_k127_8564691_19	867845.KI911784_gene3418	4.067e-18	100.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Arylsulfotran_2,Arylsulfotrans
LZS2_k127_8564691_24	1191523.MROS_2237	2.914e-05	57.0	COG0823@1|root,COG4733@1|root,COG0823@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.45	ko:K01201,ko:K13669	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000,ko01003	-	GH30,GT87	-	CBM_6,GT87,PD40
LZS2_k127_8564691_22	945713.IALB_2290	4.588e-10	66.0	2AQ71@1|root,31FCR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8564691_20	1238450.VIBNISOn1_110002	3.129e-13	79.0	COG2204@1|root,COG2204@2|Bacteria,1QUG8@1224|Proteobacteria,1T1Y0@1236|Gammaproteobacteria,1XT04@135623|Vibrionales	135623|Vibrionales	T	COG0784 FOG CheY-like receiver	rssB	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS2_k127_8564691_23	273057.SSO2796	5.043e-09	68.0	COG0457@1|root,arCOG03428@2157|Archaea	2157|Archaea	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
LZS2_k127_8564691_8	1379698.RBG1_1C00001G0815	2.627e-62	222.0	COG2316@1|root,COG2316@2|Bacteria,2NP8E@2323|unclassified Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
LZS2_k127_8564691_2	1267533.KB906736_gene1076	8.325e-151	497.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
LZS2_k127_8564691_0	880073.Calab_1578	6.649e-187	601.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS2_k127_8564691_25	717774.Marme_3765	0.0001971	53.0	2EIP2@1|root,33CEF@2|Bacteria,1QX6D@1224|Proteobacteria,1T4Z1@1236|Gammaproteobacteria,1XQUQ@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
LZS2_k127_8564691_15	1121447.JONL01000007_gene1297	1.09e-28	120.0	COG1661@1|root,COG1661@2|Bacteria,1RJC1@1224|Proteobacteria,42X02@68525|delta/epsilon subdivisions,2WT2B@28221|Deltaproteobacteria,2MFZS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
LZS2_k127_8564691_21	882083.SacmaDRAFT_1919	3.905e-12	72.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
LZS2_k127_8564691_6	429009.Adeg_0304	3.221e-93	314.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
LZS2_k127_8565284_11	123214.PERMA_0831	5.797e-30	121.0	28N7F@1|root,2ZBC4@2|Bacteria,2G4MS@200783|Aquificae	200783|Aquificae	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
LZS2_k127_8565284_6	631362.Thi970DRAFT_04903	1.42e-74	256.0	COG0310@1|root,COG0310@2|Bacteria,1RJRC@1224|Proteobacteria,1S6H0@1236|Gammaproteobacteria,1WX9R@135613|Chromatiales	135613|Chromatiales	P	PFAM Cobalt uptake substrate-specific transmembrane region	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
LZS2_k127_8565284_10	123214.PERMA_0828	3.706e-31	130.0	COG0619@1|root,COG0619@2|Bacteria,2G581@200783|Aquificae	200783|Aquificae	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	-
LZS2_k127_8565284_5	1158338.JNLJ01000001_gene1259	6.433e-99	329.0	COG1122@1|root,COG1122@2|Bacteria,2G44Q@200783|Aquificae	200783|Aquificae	P	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
LZS2_k127_8565284_7	572477.Alvin_0510	1.031e-49	181.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,1S44Q@1236|Gammaproteobacteria,1WY0B@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
LZS2_k127_8565284_1	1191523.MROS_0843	2.684e-197	623.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	cydA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iPC815.YPO1117,iSBO_1134.SBO_2253,iSFxv_1172.SFxv_0621,iS_1188.S0577,iSbBS512_1146.SbBS512_E2337	Cyt_bd_oxida_I
LZS2_k127_8565284_3	1191523.MROS_0842	2.912e-134	435.0	COG1294@1|root,COG1294@2|Bacteria	2|Bacteria	C	oxidative phosphorylation	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120	Cyt_bd_oxida_II
LZS2_k127_8565284_9	866895.HBHAL_1922	5.207e-41	164.0	COG3264@1|root,COG3264@2|Bacteria,1UIZT@1239|Firmicutes,4HCE1@91061|Bacilli,3NFFG@45667|Halobacillus	91061|Bacilli	M	Mechanosensitive ion channel	-	-	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	MS_channel
LZS2_k127_8565284_4	396588.Tgr7_0569	1.26e-106	352.0	COG0668@1|root,COG0668@2|Bacteria,1QU7U@1224|Proteobacteria,1T1Q9@1236|Gammaproteobacteria,1WZXW@135613|Chromatiales	135613|Chromatiales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS2_k127_8565284_8	1158165.KB898874_gene1660	1.861e-44	169.0	COG2430@1|root,COG2430@2|Bacteria,1N0R1@1224|Proteobacteria,1SQ9A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8565284_2	1047013.AQSP01000110_gene67	6.863e-138	447.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS2_k127_8565284_0	1191523.MROS_2800	1.036e-232	726.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
LZS2_k127_8565284_12	1095752.HMPREF9969_0579	0.0005154	48.0	COG0574@1|root,COG2197@1|root,COG0574@2|Bacteria,COG2197@2|Bacteria,4NGSQ@976|Bacteroidetes,2FM60@200643|Bacteroidia	976|Bacteroidetes	GKT	Pyruvate phosphate dikinase, PEP pyruvate binding domain	ppsA	-	-	-	-	-	-	-	-	-	-	-	PPDK_N,Response_reg
LZS2_k127_8575352_3	526227.Mesil_0662	9.231e-28	120.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	dat	-	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS2_k127_8575352_0	880073.Calab_1275	1.056e-132	431.0	COG0039@1|root,COG0039@2|Bacteria,2NNY8@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1360	Ldh_1_C,Ldh_1_N
LZS2_k127_8575352_1	357808.RoseRS_4078	2.16e-125	409.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS2_k127_8575352_2	459349.CLOAM0656	2.223e-68	239.0	COG1208@1|root,COG1208@2|Bacteria,2NPHW@2323|unclassified Bacteria	2|Bacteria	JM	Nucleotidyl transferase	mpg2	-	2.7.7.13	ko:K00966,ko:K21210	ko00051,ko00520,ko01059,ko01100,ko01110,ko01130,map00051,map00520,map01059,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R11429	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS2_k127_8575352_4	1210884.HG799467_gene13148	5.841e-08	56.0	COG0451@1|root,COG0451@2|Bacteria,2IYBF@203682|Planctomycetes	203682|Planctomycetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
LZS2_k127_8611018_3	1158146.KB907131_gene1308	3.508e-47	171.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales	135613|Chromatiales	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
LZS2_k127_8611018_2	589865.DaAHT2_0018	1.428e-60	235.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
LZS2_k127_8611018_1	335543.Sfum_1996	3.41e-125	419.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
LZS2_k127_8611018_0	1047013.AQSP01000128_gene446	3.56e-128	416.0	COG1180@1|root,COG1180@2|Bacteria,2NNMV@2323|unclassified Bacteria	2|Bacteria	O	Elongator protein 3, MiaB family, Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS2_k127_8615470_7	1123373.ATXI01000011_gene1095	3.457e-14	78.0	COG2001@1|root,COG2001@2|Bacteria,2GGT9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
LZS2_k127_8615470_5	207559.Dde_1034	3.222e-68	243.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,2M7ZZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
LZS2_k127_8615470_2	935948.KE386493_gene2325	7.998e-107	373.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,42FD0@68295|Thermoanaerobacterales	186801|Clostridia	M	TIGRFAM stage V sporulation protein D	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
LZS2_k127_8615470_1	868595.Desca_2347	1.464e-120	405.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,260X6@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_8615470_4	1121472.AQWN01000005_gene2388	1.297e-84	298.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,260TC@186807|Peptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS2_k127_8615470_0	1379698.RBG1_1C00001G0393	6.686e-153	492.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
LZS2_k127_8615470_3	671143.DAMO_2299	7.03e-97	332.0	COG0771@1|root,COG0771@2|Bacteria,2NP27@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097	Mur_ligase_C,Mur_ligase_M
LZS2_k127_8615470_6	999411.HMPREF1092_01184	3.919e-17	88.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,36EE6@31979|Clostridiaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
LZS2_k127_8635769_1	96561.Dole_2408	7.8e-67	239.0	COG2194@1|root,COG2194@2|Bacteria,1NJEC@1224|Proteobacteria	1224|Proteobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8635769_0	215803.DB30_7050	4.787e-150	486.0	COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria,439AJ@68525|delta/epsilon subdivisions,2X4I4@28221|Deltaproteobacteria,2YZ2B@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8641716_0	518766.Rmar_1363	1.878e-183	600.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS2_k127_8641716_1	1047013.AQSP01000134_gene1338	5.194e-158	522.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
LZS2_k127_8641716_6	1120985.AUMI01000016_gene1981	6.255e-21	102.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,4H3ZU@909932|Negativicutes	909932|Negativicutes	E	Vitamin B12 dependent methionine synthase activation	-	-	-	-	-	-	-	-	-	-	-	-	Met_synt_B12
LZS2_k127_8641716_3	177437.HRM2_43970	2.407e-64	232.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,43BU7@68525|delta/epsilon subdivisions,2X757@28221|Deltaproteobacteria,2MJ6M@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10,2.1.1.13	ko:K00297,ko:K00547,ko:K00548	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523	M00017,M00377	R00650,R00946,R01224,R07168,R09365	RC00003,RC00035,RC00081,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
LZS2_k127_8641716_4	1047013.AQSP01000134_gene1339	2.004e-62	221.0	COG5012@1|root,COG5012@2|Bacteria,2NQTJ@2323|unclassified Bacteria	2|Bacteria	S	B12 binding domain	-	-	-	ko:K14084	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124	RC00035,RC00732,RC02984	ko00000,ko00001,ko00002	-	-	-	B12-binding,B12-binding_2
LZS2_k127_8641716_2	1158318.ATXC01000001_gene377	5.056e-73	253.0	COG0177@1|root,COG0177@2|Bacteria,2G3TX@200783|Aquificae	200783|Aquificae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
LZS2_k127_8641716_7	1104324.P186_0653	7.689e-11	69.0	COG0456@1|root,arCOG00833@2157|Archaea	2157|Archaea	C	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.1,2.3.1.178	ko:K06718,ko:K22477	ko00220,ko00260,ko01100,ko01120,ko01210,ko01230,map00220,map00260,map01100,map01120,map01210,map01230	M00028,M00033	R00259,R06978	RC00004,RC00064,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
LZS2_k127_8641716_5	665571.STHERM_c19690	2.658e-46	180.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS2_k127_8686609_1	756272.Plabr_1344	1.029e-54	201.0	COG2148@1|root,COG2148@2|Bacteria,2IX7E@203682|Planctomycetes	203682|Planctomycetes	M	involved in lipopolysaccharide	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
LZS2_k127_8686609_0	1234364.AMSF01000010_gene552	2.758e-110	368.0	2DBFX@1|root,2Z917@2|Bacteria,1P4PR@1224|Proteobacteria,1RWCW@1236|Gammaproteobacteria,1X36T@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8686609_3	1163408.UU9_04192	2.073e-40	167.0	COG3307@1|root,COG3307@2|Bacteria,1N4HJ@1224|Proteobacteria,1SWM6@1236|Gammaproteobacteria,1X57W@135614|Xanthomonadales	135614|Xanthomonadales	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS2_k127_8686609_5	1227739.Hsw_1662	1.21e-35	152.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
LZS2_k127_8686609_2	797209.ZOD2009_15156	6.907e-48	185.0	COG0438@1|root,arCOG01415@2157|Archaea,2XUVW@28890|Euryarchaeota,23UTV@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS2_k127_8686609_4	1078085.HMPREF1210_00701	6.217e-37	148.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,26DQ3@186818|Planococcaceae	91061|Bacilli	D	COG0489 ATPases involved in chromosome partitioning	ywqD	-	2.7.10.2	ko:K00903	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,ParA
LZS2_k127_8686609_6	1449126.JQKL01000027_gene2465	2.482e-09	66.0	COG3206@1|root,COG3206@2|Bacteria,1TSJG@1239|Firmicutes,249MI@186801|Clostridia	186801|Clostridia	M	PFAM lipopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
LZS2_k127_8698689_1	1379698.RBG1_1C00001G1605	4.036e-289	902.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
LZS2_k127_8698689_0	1379698.RBG1_1C00001G1604	0.0	1875.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
LZS2_k127_8698689_2	880073.Calab_2121	1.486e-60	211.0	COG0048@1|root,COG0048@2|Bacteria,2NPA7@2323|unclassified Bacteria	2|Bacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
LZS2_k127_8698689_3	290397.Adeh_1949	1.134e-58	210.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2YUYC@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
LZS2_k127_876080_0	309807.SRU_0564	7.308e-66	233.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1FIJS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS2_k127_876080_2	667632.KB890176_gene4687	1.125e-25	123.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,1K03X@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5,Glyco_transf_41,TPR_1,TPR_10,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
LZS2_k127_876080_1	1304885.AUEY01000047_gene79	1.799e-62	231.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2MI8S@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS2_k127_8762595_5	1379698.RBG1_1C00001G0311	4.056e-28	117.0	COG0799@1|root,COG0799@2|Bacteria,2NPYI@2323|unclassified Bacteria	2|Bacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	2.7.7.18	ko:K00969,ko:K09710	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RsfS
LZS2_k127_8762595_0	656519.Halsa_0380	1.529e-135	451.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,3WAQ7@53433|Halanaerobiales	186801|Clostridia	J	Arginyl tRNA synthetase N terminal domain	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
LZS2_k127_8762595_2	378806.STAUR_4220	4.836e-89	303.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
LZS2_k127_8762595_6	246194.CHY_0159	1.704e-26	118.0	2DMAW@1|root,32EM1@2|Bacteria,1UPNC@1239|Firmicutes,25HJQ@186801|Clostridia,42JH2@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8762595_4	635013.TherJR_2774	6.883e-76	271.0	COG3437@1|root,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,267DF@186807|Peptococcaceae	186801|Clostridia	KT	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,Hpt,Response_reg
LZS2_k127_8762595_1	1379698.RBG1_1C00001G0378	3.234e-102	349.0	COG0150@1|root,COG0150@2|Bacteria,2NNUJ@2323|unclassified Bacteria	2|Bacteria	F	AIR synthase related protein, N-terminal domain	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.1,6.3.4.13	ko:K01933,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844,iECSF_1327.ECSF_2340	AIRS,AIRS_C
LZS2_k127_8762595_3	237368.SCABRO_01504	3.819e-88	298.0	COG0659@1|root,COG0659@2|Bacteria,2IX8K@203682|Planctomycetes	203682|Planctomycetes	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
LZS2_k127_8791188_6	945713.IALB_1510	6.746e-80	281.0	COG0860@1|root,COG5492@1|root,COG0860@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.5.1.28	ko:K01448,ko:K21471	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036	-	-	-	Amidase_3,CHAP,Cu_amine_oxidN1,GBS_Bsp-like,TIG
LZS2_k127_8791188_1	1191523.MROS_2644	1.68e-179	597.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug,TonB_dep_Rec
LZS2_k127_8791188_2	1379698.RBG1_1C00001G0518	3.188e-160	529.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS2_k127_8791188_5	1121405.dsmv_2612	5.88e-140	453.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2MJ2T@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS2_k127_8791188_0	1121405.dsmv_2611	2.347e-309	966.0	COG0603@1|root,COG1402@1|root,COG0603@2|Bacteria,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2X9RQ@28221|Deltaproteobacteria,2MPA0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS2_k127_8791188_3	1121405.dsmv_2609	4.466e-153	494.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,42PSH@68525|delta/epsilon subdivisions,2WJYZ@28221|Deltaproteobacteria,2MIFM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
LZS2_k127_8791188_4	1121405.dsmv_2608	9.488e-151	487.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	-	-	2.5.1.76,4.2.3.1	ko:K01733,ko:K15527	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,PALP
LZS2_k127_8791188_7	1158338.JNLJ01000001_gene1009	7.067e-61	225.0	COG5266@1|root,COG5266@2|Bacteria	2|Bacteria	P	PFAM Nickel transport complex, NikM subunit, transmembrane	cbiK	-	-	ko:K10094	ko02010,map02010	M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.22	-	-	DUF4198
LZS2_k127_8791188_8	631362.Thi970DRAFT_04905	1.073e-33	135.0	COG5266@1|root,COG5266@2|Bacteria,1NBJ8@1224|Proteobacteria,1SGZC@1236|Gammaproteobacteria,1X2PI@135613|Chromatiales	135613|Chromatiales	P	PFAM Nickel transport complex, NikM subunit, transmembrane	-	-	-	ko:K16915	ko02010,map02010	M00246	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	-
LZS2_k127_8792283_6	525309.HMPREF0494_1821	1.964e-28	119.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
LZS2_k127_8792283_0	880073.Calab_2050	9.75e-152	491.0	COG0541@1|root,COG0541@2|Bacteria,2NNT9@2323|unclassified Bacteria	2|Bacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
LZS2_k127_8792283_3	1131730.BAVI_20154	1.163e-66	236.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1ZCUF@1386|Bacillus	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
LZS2_k127_8792283_8	59374.Fisuc_1629	1.206e-19	99.0	COG2815@1|root,COG2815@2|Bacteria	2|Bacteria	G	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS2_k127_8792283_2	269799.Gmet_3339	1.25e-80	280.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
LZS2_k127_8792283_4	232348.ADXL01000034_gene1391	2.672e-37	147.0	COG0242@1|root,COG0242@2|Bacteria,1G1FB@1117|Cyanobacteria,1GZM4@1129|Synechococcus	1117|Cyanobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
LZS2_k127_8792283_7	1121405.dsmv_0961	4.336e-22	100.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2MKCK@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
LZS2_k127_8792283_1	1191523.MROS_2719	2.63e-134	438.0	COG0343@1|root,COG0343@2|Bacteria	2|Bacteria	F	queuine tRNA-ribosyltransferase activity	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
LZS2_k127_8792283_5	373994.Riv7116_0788	8.76e-37	142.0	COG0809@1|root,COG0809@2|Bacteria,1G02D@1117|Cyanobacteria,1HJ1X@1161|Nostocales	1117|Cyanobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
LZS2_k127_8814901_2	1121468.AUBR01000045_gene1808	1.439e-36	147.0	COG1413@1|root,COG1413@2|Bacteria,1VFIG@1239|Firmicutes,24STM@186801|Clostridia,42H7D@68295|Thermoanaerobacterales	186801|Clostridia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_EZ
LZS2_k127_8814901_1	378806.STAUR_1526	1.322e-54	202.0	COG0702@1|root,COG0702@2|Bacteria,1PGSR@1224|Proteobacteria,438XT@68525|delta/epsilon subdivisions,2X43B@28221|Deltaproteobacteria,2YY5A@29|Myxococcales	28221|Deltaproteobacteria	GM	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
LZS2_k127_8814901_0	1047013.AQSP01000106_gene1757	6.508e-233	737.0	COG4690@1|root,COG4690@2|Bacteria,2NQBZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
LZS2_k127_8814901_4	880073.Calab_2214	3.776e-05	57.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	-
LZS2_k127_8814901_3	595460.RRSWK_05435	2.302e-09	70.0	2EYTK@1|root,33S0U@2|Bacteria,2IYA9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1
LZS2_k127_8833434_3	584708.Apau_1447	2.243e-32	136.0	COG0406@1|root,COG0406@2|Bacteria,3TAZ5@508458|Synergistetes	508458|Synergistetes	G	phosphoglycerate mutase family	-	-	3.1.3.3	ko:K22305	ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130	-	R00582	RC00017	ko00000,ko00001,ko01000	-	-	-	His_Phos_1
LZS2_k127_8833434_1	706587.Desti_2460	4.23e-62	219.0	299T8@1|root,2ZWVF@2|Bacteria,1N5QA@1224|Proteobacteria,42ZI5@68525|delta/epsilon subdivisions,2WV28@28221|Deltaproteobacteria,2MRN5@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_8833434_2	1454004.AW11_00145	7.136e-46	174.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,2WGT1@28216|Betaproteobacteria,1KQVZ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS2_k127_8833434_0	552811.Dehly_1422	8.406e-78	268.0	COG0500@1|root,COG2226@2|Bacteria,2G6GD@200795|Chloroflexi,34CS0@301297|Dehalococcoidia	301297|Dehalococcoidia	Q	Ribosomal protein L11 methyltransferase (PrmA)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
LZS2_k127_8874171_2	1379698.RBG1_1C00001G1345	1.267e-50	196.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
LZS2_k127_8874171_3	883156.HMPREF9282_01551	1.513e-27	117.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4H4P5@909932|Negativicutes	909932|Negativicutes	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
LZS2_k127_8874171_1	671143.DAMO_2059	4.424e-64	232.0	COG1559@1|root,COG1559@2|Bacteria,2NP75@2323|unclassified Bacteria	2|Bacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
LZS2_k127_8874171_0	204669.Acid345_0159	1.526e-72	256.0	COG1606@1|root,COG1606@2|Bacteria,3Y30C@57723|Acidobacteria,2JKD3@204432|Acidobacteriia	204432|Acidobacteriia	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
LZS2_k127_8874171_4	880073.Calab_1286	7.784e-15	87.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
LZS2_k127_8932315_4	1077285.AGDG01000004_gene2316	0.0003137	54.0	COG0457@1|root,COG1729@1|root,COG4105@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,COG4105@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia,4AM5H@815|Bacteroidaceae	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
LZS2_k127_8932315_0	1379698.RBG1_1C00001G0659	0.0	1181.0	COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS2_k127_8932315_2	373903.Hore_23440	2.141e-108	362.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,3WBC4@53433|Halanaerobiales	186801|Clostridia	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
LZS2_k127_8932315_3	1121104.AQXH01000001_gene1089	1.265e-41	156.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,1IT1E@117747|Sphingobacteriia	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
LZS2_k127_8932315_1	457570.Nther_2749	3.773e-134	441.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS2_k127_917651_4	880073.Calab_0505	3.683e-49	181.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS2_k127_917651_0	1379698.RBG1_1C00001G0509	8.346e-203	653.0	COG1042@1|root,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria	2|Bacteria	C	synthetase (ADP forming), alpha	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
LZS2_k127_917651_5	517418.Ctha_0672	1.766e-28	126.0	2DS9E@1|root,32VU1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_917651_1	1379270.AUXF01000001_gene1951	4.097e-150	488.0	COG0577@1|root,COG0577@2|Bacteria,1ZSUJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS2_k127_917651_3	1379270.AUXF01000001_gene1950	2.821e-92	309.0	COG1136@1|root,COG1136@2|Bacteria,1ZUSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS2_k127_917651_2	379066.GAU_0845	6.746e-100	340.0	COG0845@1|root,COG0845@2|Bacteria,1ZU07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
LZS2_k127_917651_6	1408473.JHXO01000001_gene2337	8.027e-11	65.0	COG1595@1|root,COG1595@2|Bacteria,4NQTP@976|Bacteroidetes,2FU81@200643|Bacteroidia	976|Bacteroidetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS2_k127_92013_3	1267533.KB906735_gene4820	4.367e-12	69.0	2DRFV@1|root,33BJD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
LZS2_k127_92013_1	926550.CLDAP_29650	2.231e-35	144.0	COG1503@1|root,COG1503@2|Bacteria,2G6UJ@200795|Chloroflexi	200795|Chloroflexi	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_92013_0	373903.Hore_13580	3.72e-97	332.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
LZS2_k127_930292_1	1379698.RBG1_1C00001G1334	3.75e-33	146.0	COG2067@1|root,COG2067@2|Bacteria,2NQKU@2323|unclassified Bacteria	2|Bacteria	I	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
LZS2_k127_930292_0	880073.Calab_0681	6.543e-171	591.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	pkn5	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1
LZS2_k127_930292_2	880073.Calab_0680	1.244e-18	103.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS2_k127_930292_3	1379698.RBG1_1C00001G1332	2.08e-15	92.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS2_k127_930292_4	502025.Hoch_4669	2.022e-13	72.0	COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS2_k127_954981_1	880073.Calab_1544	1.071e-38	151.0	COG3342@1|root,COG3342@2|Bacteria,2NP87@2323|unclassified Bacteria	2|Bacteria	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,TPR_16,TPR_19
LZS2_k127_954981_0	420324.KI912037_gene2370	1.124e-129	432.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,1JXS3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	the N-terminal amino acid	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
LZS2_k127_96199_7	511051.CSE_05780	7.238e-07	51.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
LZS2_k127_96199_1	861299.J421_3894	1.093e-101	347.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS2_k127_96199_5	333138.LQ50_04240	2.097e-22	102.0	COG0789@1|root,COG0789@2|Bacteria,1UV89@1239|Firmicutes,4I2YZ@91061|Bacilli,1ZI3D@1386|Bacillus	91061|Bacilli	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
LZS2_k127_96199_2	1182590.BN5_02402	1.194e-100	345.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K11914	-	-	-	-	ko00000,ko02044,ko03000	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
LZS2_k127_96199_4	768671.ThimaDRAFT_4336	3.068e-35	141.0	2C9YI@1|root,337RN@2|Bacteria,1NBDR@1224|Proteobacteria,1SW2H@1236|Gammaproteobacteria,1X203@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_96199_6	665571.STHERM_c10960	4.504e-10	70.0	COG3829@1|root,COG3829@2|Bacteria,2J63K@203691|Spirochaetes	203691|Spirochaetes	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
LZS2_k127_96199_0	177439.DP1964	4.25e-122	426.0	COG1470@1|root,COG4932@1|root,COG1470@2|Bacteria,COG4932@2|Bacteria,1R7QK@1224|Proteobacteria,42Z8R@68525|delta/epsilon subdivisions,2WTWG@28221|Deltaproteobacteria,2MMY9@213118|Desulfobacterales	28221|Deltaproteobacteria	M	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_96199_3	1121405.dsmv_1672	4.823e-65	232.0	COG3121@1|root,COG3121@2|Bacteria,1RCF5@1224|Proteobacteria,42Y7D@68525|delta/epsilon subdivisions,2WTKP@28221|Deltaproteobacteria,2MMT2@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS2_k127_96199_8	76114.ebA2787	5.724e-05	46.0	2C9YI@1|root,337RN@2|Bacteria,1NBDR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 2423 queries scanned
## Total time (seconds): 250.85379266738892
## Rate: 9.66 q/s