## Thu Oct 17 09:02:59 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/LZS3_bin.116.fa -m mmseqs --itype genome -o LZS3_bin.116 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/LZS3_bin.116 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
LZS3_k127_1024827_2	44454.NF84_03255	1.028e-21	98.0	COG0599@1|root,COG0599@2|Bacteria,2IFMB@201174|Actinobacteria,238R6@1762|Mycobacteriaceae	201174|Actinobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
LZS3_k127_1024827_1	1122604.JONR01000022_gene634	3.496e-54	201.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1X9FG@135614|Xanthomonadales	135614|Xanthomonadales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
LZS3_k127_1024827_0	1229780.BN381_170020	1.227e-145	473.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	cyp123A3	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_1043072_2	1123070.KB899254_gene1284	6.38e-31	124.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS3_k127_1043072_0	264462.Bd0368	3.355e-76	270.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2MUP9@213481|Bdellovibrionales,2WMIS@28221|Deltaproteobacteria	213481|Bdellovibrionales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
LZS3_k127_1043072_1	869210.Marky_0290	3.755e-41	160.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
LZS3_k127_1043236_1	391625.PPSIR1_19754	2.536e-46	177.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,431ED@68525|delta/epsilon subdivisions,2WWZ0@28221|Deltaproteobacteria,2YVD5@29|Myxococcales	28221|Deltaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
LZS3_k127_1043236_0	1283300.ATXB01000001_gene444	1.127e-98	332.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,1XDYA@135618|Methylococcales	135618|Methylococcales	Q	Flavin containing amine oxidoreductase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS3_k127_1047536_3	1282876.BAOK01000001_gene1825	2.74e-29	128.0	COG0625@1|root,COG0625@2|Bacteria,1R6UY@1224|Proteobacteria,2U1WS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
LZS3_k127_1047536_2	588932.JHOF01000023_gene1903	1.596e-31	136.0	2E0BU@1|root,32VYY@2|Bacteria,1N1HC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1047536_1	1280946.HY29_16665	1.709e-33	133.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,43WFY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_1047536_0	1280952.HJA_05882	1.162e-53	195.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,43WFY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_10485_4	56780.SYN_01692	5.593e-42	167.0	COG0204@1|root,COG0204@2|Bacteria,1P3XM@1224|Proteobacteria	1224|Proteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS3_k127_10485_7	889378.Spiaf_2287	4.286e-15	78.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS3_k127_10485_0	56780.SYN_01694	2.983e-157	513.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2MQ97@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_10485_6	56780.SYN_01695	3.338e-33	133.0	COG0764@1|root,COG0764@2|Bacteria,1N0HJ@1224|Proteobacteria,42ZU6@68525|delta/epsilon subdivisions,2WV96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	FabA-like domain	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
LZS3_k127_10485_2	56780.SYN_01696	2.344e-79	281.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2MQF5@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_10485_3	889378.Spiaf_2284	8.059e-74	254.0	COG0764@1|root,COG0764@2|Bacteria	2|Bacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	fabA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019171,GO:0019752,GO:0032787,GO:0034017,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b0954,iB21_1397.B21_00965,iBWG_1329.BWG_0806,iE2348C_1286.E2348C_0940,iEC042_1314.EC042_1039,iECBD_1354.ECBD_2641,iECB_1328.ECB_00958,iECDH10B_1368.ECDH10B_1024,iECD_1391.ECD_00958,iECED1_1282.ECED1_0977,iECH74115_1262.ECH74115_1118,iECIAI1_1343.ECIAI1_0995,iECIAI39_1322.ECIAI39_2193,iECNA114_1301.ECNA114_1032,iECO103_1326.ECO103_1000,iECO111_1330.ECO111_1022,iECO26_1355.ECO26_1081,iECOK1_1307.ECOK1_1013,iECS88_1305.ECS88_0975,iECSF_1327.ECSF_0868,iECSP_1301.ECSP_1060,iECUMN_1333.ECUMN_1143,iECW_1372.ECW_m1064,iECs_1301.ECs1038,iEKO11_1354.EKO11_2876,iETEC_1333.ETEC_1024,iEcE24377_1341.EcE24377A_1068,iEcHS_1320.EcHS_A1063,iEcSMS35_1347.EcSMS35_2166,iEcolC_1368.EcolC_2642,iG2583_1286.G2583_1189,iJO1366.b0954,iJR904.b0954,iLF82_1304.LF82_0604,iSBO_1134.SBO_2277,iSDY_1059.SDY_0927,iSF_1195.SF0954,iSSON_1240.SSON_0958,iSbBS512_1146.SbBS512_E2362,iUMNK88_1353.UMNK88_1108,iWFL_1372.ECW_m1064,iY75_1357.Y75_RS04955,iZ_1308.Z1304,ic_1306.c1090	FabA
LZS3_k127_10485_1	439235.Dalk_1753	1.121e-106	356.0	COG0300@1|root,COG0623@1|root,COG0300@2|Bacteria,COG0623@2|Bacteria,1R090@1224|Proteobacteria,43CRU@68525|delta/epsilon subdivisions,2X7ZF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_10485_5	714943.Mucpa_3155	5.009e-38	151.0	COG1028@1|root,COG1028@2|Bacteria,4P0BT@976|Bacteroidetes,1IWK3@117747|Sphingobacteriia	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_1061332_1	1347086.CCBA010000044_gene2410	2.419e-13	78.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,1ZH54@1386|Bacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
LZS3_k127_1061332_0	525897.Dbac_3352	5.447e-109	374.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria,2M8AC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
LZS3_k127_1063612_3	697303.Thewi_2565	0.0002456	48.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,42GD3@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS3_k127_1063612_0	644282.Deba_0727	3.608e-121	397.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
LZS3_k127_1063612_1	1121468.AUBR01000004_gene200	1.388e-45	173.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,42G72@68295|Thermoanaerobacterales	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
LZS3_k127_1063612_2	1380394.JADL01000001_gene2623	3.018e-11	65.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,2JRYN@204441|Rhodospirillales	204441|Rhodospirillales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
LZS3_k127_1063637_0	1123242.JH636434_gene3443	2.301e-107	361.0	COG4412@1|root,COG4412@2|Bacteria,2J16X@203682|Planctomycetes	203682|Planctomycetes	O	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
LZS3_k127_1064841_0	290397.Adeh_3944	5.629e-170	546.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2YWVA@29|Myxococcales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS3_k127_1064841_1	330214.NIDE0014	4.517e-110	368.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_1064841_7	1156844.KB891801_gene2794	9.182e-05	55.0	COG3631@1|root,COG3631@2|Bacteria,2IJQH@201174|Actinobacteria	201174|Actinobacteria	S	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
LZS3_k127_1064841_6	713586.KB900536_gene2513	1.095e-08	63.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,1S1FB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
LZS3_k127_1064841_5	436229.JOEH01000008_gene4199	1.073e-14	87.0	COG0477@1|root,COG2814@2|Bacteria,2GJF6@201174|Actinobacteria,2NGVR@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1064841_2	187272.Mlg_2074	2.091e-36	143.0	COG0517@1|root,COG0517@2|Bacteria,1N2XI@1224|Proteobacteria,1SA5K@1236|Gammaproteobacteria,1WZKX@135613|Chromatiales	135613|Chromatiales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS
LZS3_k127_1064841_3	1121033.AUCF01000006_gene4087	1.979e-33	135.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2U3AB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Belongs to the ribose-phosphate pyrophosphokinase family	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
LZS3_k127_1079480_0	292459.STH1547	1.456e-118	391.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS3_k127_1084682_1	1211815.CBYP010000063_gene1911	3.195e-224	721.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4EU7X@85013|Frankiales	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
LZS3_k127_1084682_0	1211815.CBYP010000063_gene1912	8.458e-269	840.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
LZS3_k127_1085036_2	1128427.KB904821_gene4098	4.712e-10	67.0	COG0483@1|root,COG0483@2|Bacteria,1G2AN@1117|Cyanobacteria,1H75P@1150|Oscillatoriales	1117|Cyanobacteria	G	Inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
LZS3_k127_1085036_1	1207063.P24_09251	6.311e-147	480.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,2VC6I@28211|Alphaproteobacteria,2JXZW@204441|Rhodospirillales	204441|Rhodospirillales	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS3_k127_1085036_0	1207063.P24_09256	1.019e-187	632.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria	1224|Proteobacteria	P	transport system permease component	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS3_k127_1117786_4	936455.KI421499_gene2698	2.91e-08	61.0	2E3ZS@1|root,32YWP@2|Bacteria,1NAZV@1224|Proteobacteria,2UGW3@28211|Alphaproteobacteria,3K0DR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1117786_5	1247963.JPHU01000001_gene1797	1.382e-07	55.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,2UJXH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1117786_0	1121861.KB899936_gene348	2.152e-234	738.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,2JRX0@204441|Rhodospirillales	204441|Rhodospirillales	O	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
LZS3_k127_1117786_2	870187.Thini_3469	7.494e-53	214.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
LZS3_k127_1117786_3	1219045.BV98_000213	1.127e-18	94.0	COG1309@1|root,COG1309@2|Bacteria,1NM2A@1224|Proteobacteria,2VE44@28211|Alphaproteobacteria,2K3MQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
LZS3_k127_1117786_1	557599.MKAN_07645	3.778e-122	414.0	COG2124@1|root,COG2124@2|Bacteria,2GKKN@201174|Actinobacteria,23477@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.15.13	ko:K17474	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
LZS3_k127_1138223_0	1123261.AXDW01000007_gene2293	5.005e-52	195.0	COG0657@1|root,COG0657@2|Bacteria,1Q14N@1224|Proteobacteria,1RZIY@1236|Gammaproteobacteria,1X7DR@135614|Xanthomonadales	135614|Xanthomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
LZS3_k127_1138223_2	713587.THITH_17370	2.216e-14	81.0	COG0575@1|root,COG0575@2|Bacteria	2|Bacteria	I	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41,2.7.7.67	ko:K00981,ko:K19664	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799,R08966	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1397	CTP_transf_1,CarS-like
LZS3_k127_1138223_1	266117.Rxyl_1135	3.506e-16	83.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS3_k127_1147569_1	525909.Afer_0297	1.245e-35	151.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4CNVW@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS3_k127_1147569_0	1429046.RR21198_4793	0.0	1150.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4G9H7@85025|Nocardiaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	adhE	-	1.1.1.1,1.2.1.10,1.2.1.81	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
LZS3_k127_1147973_1	1242864.D187_002019	2.534e-44	169.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS3_k127_1147973_0	1278073.MYSTI_04606	5.325e-55	201.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2YVUS@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_1147973_2	1121106.JQKB01000012_gene4569	1.215e-06	57.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,2JPF3@204441|Rhodospirillales	204441|Rhodospirillales	D	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
LZS3_k127_1148812_0	446470.Snas_3073	6.505e-119	399.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
LZS3_k127_1148812_1	103733.JNYO01000080_gene5009	0.0003096	53.0	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria,4EC3N@85010|Pseudonocardiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_1164983_0	448385.sce0176	1.287e-101	340.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42PRS@68525|delta/epsilon subdivisions,2X5EU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS3_k127_1164983_1	710687.KI912270_gene1022	2.018e-34	153.0	COG2114@1|root,COG2909@1|root,COG3629@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3629@2|Bacteria,2GJAR@201174|Actinobacteria,2349V@1762|Mycobacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
LZS3_k127_1166553_1	316274.Haur_3798	1.066e-93	321.0	COG0318@1|root,COG0318@2|Bacteria,2G5K4@200795|Chloroflexi,3758A@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_1166553_0	575540.Isop_1639	3.148e-118	394.0	COG0399@1|root,COG0399@2|Bacteria,2IXRE@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_1174058_7	1254432.SCE1572_12540	6.792e-19	97.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria,42Y1U@68525|delta/epsilon subdivisions,2WNPK@28221|Deltaproteobacteria,2Z01S@29|Myxococcales	28221|Deltaproteobacteria	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
LZS3_k127_1174058_6	1123256.KB907932_gene2877	2.664e-31	132.0	COG2834@1|root,COG2834@2|Bacteria,1PD04@1224|Proteobacteria,1SY69@1236|Gammaproteobacteria,1X79C@135614|Xanthomonadales	135614|Xanthomonadales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
LZS3_k127_1174058_1	570268.ANBB01000058_gene4272	7.664e-112	407.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria,4EJ4K@85012|Streptosporangiales	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
LZS3_k127_1174058_5	1229780.BN381_150064	4.007e-36	158.0	COG1409@1|root,COG1409@2|Bacteria,2IDNH@201174|Actinobacteria	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos,Pur_ac_phosph_N
LZS3_k127_1174058_2	1229780.BN381_40090	1.202e-92	346.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_1174058_3	228405.HNE_0924	3.854e-79	272.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,43XCC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	IQ	short chain dehydrogenase reductase family	-	-	1.1.1.304,1.1.1.76	ko:K18009	ko00650,map00650	-	R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
LZS3_k127_1174058_4	1380394.JADL01000013_gene690	7.027e-54	197.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria,2JSP4@204441|Rhodospirillales	204441|Rhodospirillales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_1174058_0	1282876.BAOK01000002_gene668	8.921e-179	582.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2TU6Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_118518_1	31234.CRE29745	2.393e-12	77.0	KOG3546@1|root,KOG3546@2759|Eukaryota,38I1B@33154|Opisthokonta,3BAXZ@33208|Metazoa,3CTMW@33213|Bilateria,40BNX@6231|Nematoda,1KUQP@119089|Chromadorea,40W2V@6236|Rhabditida	33208|Metazoa	W	Collagenase NC10 and Endostatin	cle-1	GO:0000902,GO:0000904,GO:0001764,GO:0003008,GO:0003012,GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005581,GO:0005604,GO:0006928,GO:0006935,GO:0006996,GO:0007005,GO:0007154,GO:0007267,GO:0007268,GO:0007271,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0008045,GO:0008104,GO:0008150,GO:0009605,GO:0009653,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0014732,GO:0014887,GO:0014888,GO:0014889,GO:0014891,GO:0014899,GO:0016043,GO:0016477,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030054,GO:0030154,GO:0030182,GO:0030198,GO:0030246,GO:0031012,GO:0031175,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0035418,GO:0040011,GO:0040039,GO:0042221,GO:0042330,GO:0043062,GO:0043500,GO:0043501,GO:0044421,GO:0048468,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050808,GO:0050896,GO:0051179,GO:0051674,GO:0061564,GO:0062023,GO:0065007,GO:0071711,GO:0071840,GO:0097485,GO:0098916,GO:0099536,GO:0099537,GO:0120036,GO:0120039,GO:2001044,GO:2001046	-	ko:K06823,ko:K08135	ko04974,map04974	-	-	-	ko00000,ko00001,ko00535,ko00536,ko04147,ko04516	-	-	-	Collagen,Endostatin,fn3
LZS3_k127_118518_0	1254432.SCE1572_44220	1.817e-94	317.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,42PXZ@68525|delta/epsilon subdivisions,2X667@28221|Deltaproteobacteria,2Z33M@29|Myxococcales	28221|Deltaproteobacteria	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
LZS3_k127_120147_0	1123258.AQXZ01000011_gene1655	7.985e-135	447.0	COG1132@1|root,COG1132@2|Bacteria,2GJYK@201174|Actinobacteria,4G01K@85025|Nocardiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS3_k127_1209323_1	69395.JQLZ01000008_gene2447	2.301e-07	62.0	2C39R@1|root,32UYY@2|Bacteria,1N8ND@1224|Proteobacteria,2UFIK@28211|Alphaproteobacteria,2KJJV@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1209323_0	1122604.JONR01000016_gene4468	7.523e-92	324.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1X35S@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
LZS3_k127_1213065_0	338966.Ppro_3691	7.243e-15	84.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42QPB@68525|delta/epsilon subdivisions,2WTIH@28221|Deltaproteobacteria,43UCI@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_1227327_1	671143.DAMO_0264	1.884e-134	456.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606,ko:K20997	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
LZS3_k127_1227327_2	1125863.JAFN01000001_gene909	1.866e-91	311.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
LZS3_k127_1227327_0	671143.DAMO_1541	2.73e-143	466.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
LZS3_k127_1227327_3	867903.ThesuDRAFT_00621	4.57e-07	55.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3WD6Q@538999|Clostridiales incertae sedis	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
LZS3_k127_1230278_0	159087.Daro_1562	3.477e-114	374.0	COG1668@1|root,COG1668@2|Bacteria,1QWGC@1224|Proteobacteria,2WGYV@28216|Betaproteobacteria,2KZQ1@206389|Rhodocyclales	206389|Rhodocyclales	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
LZS3_k127_1238733_3	1121943.KB900004_gene2890	6.261e-13	70.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1XJPI@135619|Oceanospirillales	135619|Oceanospirillales	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
LZS3_k127_1238733_2	1229780.BN381_210089	1.9e-158	512.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,3UWAM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
LZS3_k127_1238733_0	243231.GSU3262	1.149e-279	900.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,43U9W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
LZS3_k127_1238733_1	1125863.JAFN01000001_gene1129	4.368e-163	537.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
LZS3_k127_1262964_9	502025.Hoch_4835	2.503e-30	126.0	COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,42NV8@68525|delta/epsilon subdivisions,2WJIW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DEAD_2	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
LZS3_k127_1262964_6	1232410.KI421418_gene2200	7.733e-72	254.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,439XF@68525|delta/epsilon subdivisions,2X9PG@28221|Deltaproteobacteria,43SVQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS3_k127_1262964_4	485913.Krac_4258	5.309e-83	290.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS3_k127_1262964_1	240016.ABIZ01000001_gene4417	5.226e-220	699.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,2ITSM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_1262964_7	744872.Spica_2691	1.189e-45	171.0	COG0440@1|root,COG0440@2|Bacteria,2J7CQ@203691|Spirochaetes	203691|Spirochaetes	E	Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
LZS3_k127_1262964_0	395493.BegalDRAFT_1084	3.137e-265	861.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,4608Q@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
LZS3_k127_1262964_2	1168065.DOK_08889	1.763e-202	675.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1J5AG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
LZS3_k127_1262964_11	1267005.KB911255_gene2398	9.847e-26	119.0	2BZCJ@1|root,32R4T@2|Bacteria,1N45I@1224|Proteobacteria,2U9A8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1262964_5	1380394.JADL01000009_gene3338	2.208e-79	274.0	COG3128@1|root,COG3128@2|Bacteria,1NZ60@1224|Proteobacteria,2TV1H@28211|Alphaproteobacteria,2JSX7@204441|Rhodospirillales	204441|Rhodospirillales	S	2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1262964_3	876044.IMCC3088_7	2.546e-84	300.0	COG1024@1|root,COG1024@2|Bacteria,1R3Q4@1224|Proteobacteria,1RQ45@1236|Gammaproteobacteria,1JA3K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_1262964_10	1157637.KB892091_gene5518	1.033e-27	132.0	COG1520@1|root,COG3420@1|root,COG1520@2|Bacteria,COG3420@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
LZS3_k127_1262964_8	330214.NIDE1927	1.416e-30	134.0	COG0589@1|root,COG0589@2|Bacteria,3J1A7@40117|Nitrospirae	40117|Nitrospirae	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_1297423_2	34007.IT40_14415	3.229e-05	52.0	COG2050@1|root,COG2050@2|Bacteria,1RHK6@1224|Proteobacteria,2U72Z@28211|Alphaproteobacteria,2PWWE@265|Paracoccus	28211|Alphaproteobacteria	Q	Thioesterase superfamily	MA20_04725	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS3_k127_1297423_0	366602.Caul_5303	1.031e-158	518.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,2KF1F@204458|Caulobacterales	204458|Caulobacterales	E	Converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_1297423_1	316055.RPE_2080	8.049e-53	194.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,3JSY1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS3_k127_1304144_0	1121405.dsmv_2190	2.215e-82	288.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,2MIMN@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Peptidoglycan-binding domain 1 protein	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
LZS3_k127_1304144_1	717605.Theco_1606	1.171e-40	162.0	COG5146@1|root,COG5146@2|Bacteria,1V2R2@1239|Firmicutes,4HG04@91061|Bacilli,26X2U@186822|Paenibacillaceae	91061|Bacilli	H	Fumble	coaW	-	2.7.1.33	ko:K09680	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumble
LZS3_k127_1311713_8	1552758.NC00_15145	9.71e-20	106.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Autotransporter,Big_3_2,CAP,Calx-beta,DUF11,DUF4347,Exo_endo_phos,He_PIG,fn3
LZS3_k127_1311713_3	1121937.AUHJ01000005_gene2226	3.395e-90	329.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,1SWMP@1236|Gammaproteobacteria,46975@72275|Alteromonadaceae	1224|Proteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_1311713_2	1313172.YM304_41580	2.155e-135	444.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	fabH	-	2.3.1.180,2.3.1.207	ko:K00648,ko:K16872	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iIT341.HP0202	ACP_syn_III,ACP_syn_III_C
LZS3_k127_1311713_1	1123284.KB899048_gene1589	2.412e-154	509.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,26NEF@186821|Sporolactobacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_1311713_0	1123256.KB907932_gene2876	4.009e-169	564.0	COG0664@1|root,COG1033@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1X3P5@135614|Xanthomonadales	135614|Xanthomonadales	T	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	-	-	-	-	-	-	-	-	-	MMPL,cNMP_binding
LZS3_k127_1311713_6	290397.Adeh_0078	1.075e-41	162.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1311713_4	1120936.KB907226_gene2797	9.496e-56	203.0	COG4689@1|root,COG4689@2|Bacteria,2GJWN@201174|Actinobacteria,4EI2S@85012|Streptosporangiales	201174|Actinobacteria	Q	Acetoacetate decarboxylase (ADC)	-	-	-	-	-	-	-	-	-	-	-	-	ADC
LZS3_k127_1311713_7	378806.STAUR_1349	1.964e-27	127.0	COG2259@1|root,COG2259@2|Bacteria,1NCQT@1224|Proteobacteria,42WUM@68525|delta/epsilon subdivisions	2|Bacteria	S	DoxX	Z012_09115	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
LZS3_k127_1311713_9	1123277.KB893172_gene717	1.353e-07	63.0	COG2010@1|root,COG2010@2|Bacteria,4PPRH@976|Bacteroidetes,47YQV@768503|Cytophagia	976|Bacteroidetes	C	Copper type II ascorbate-dependent monooxygenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C
LZS3_k127_13133_4	469383.Cwoe_1065	2.478e-71	264.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4CS06@84995|Rubrobacteria	84995|Rubrobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_13133_3	1122197.ATWI01000016_gene2198	2.325e-90	331.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,1RQ2R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	3-beta hydroxysteroid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_13133_1	1229780.BN381_310101	7.612e-209	664.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,3UXSH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_13133_2	381666.H16_A1980	2.489e-91	334.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2VJYK@28216|Betaproteobacteria,1K220@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_13133_11	180281.CPCC7001_1775	8.316e-19	101.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1G0CZ@1117|Cyanobacteria,22TAG@167375|Cyanobium	1117|Cyanobacteria	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
LZS3_k127_13133_5	1240349.ANGC01000053_gene4174	5.256e-69	253.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4G55D@85025|Nocardiaceae	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS3_k127_13133_7	78245.Xaut_2895	2.818e-38	151.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2UCDT@28211|Alphaproteobacteria,3EZR0@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
LZS3_k127_13133_8	1131813.AQVT01000001_gene3586	2.988e-36	149.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2U99K@28211|Alphaproteobacteria,1JV5Y@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	-
LZS3_k127_13133_10	1463855.JOHV01000046_gene250	4.14e-19	99.0	COG0607@1|root,COG0607@2|Bacteria,2IB6H@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
LZS3_k127_13133_6	666684.AfiDRAFT_1076	1.197e-47	186.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2U66N@28211|Alphaproteobacteria,3JYD3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
LZS3_k127_13133_9	404589.Anae109_3112	4.46e-23	103.0	2BW7N@1|root,32Z97@2|Bacteria,1P2ZF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_13133_0	404589.Anae109_1631	2.002e-256	803.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2YUEB@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
LZS3_k127_13133_12	448385.sce3166	1.955e-17	86.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42MK8@68525|delta/epsilon subdivisions,2WMI7@28221|Deltaproteobacteria,2YY33@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS3_k127_1322060_1	1232410.KI421424_gene1723	7.807e-135	439.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ central domain	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS3_k127_1322060_0	56780.SYN_01983	1.111e-255	801.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MR7D@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS3_k127_1322060_3	338963.Pcar_0108	2.815e-30	138.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria,43US5@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	GrpE	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS3_k127_1322060_2	340.xcc-b100_2801	1.081e-48	188.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1X44P@135614|Xanthomonadales	135614|Xanthomonadales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
LZS3_k127_1333465_0	1191523.MROS_2334	4.299e-104	349.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
LZS3_k127_1392770_1	472759.Nhal_0690	3.069e-99	337.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,1WWK5@135613|Chromatiales	135613|Chromatiales	O	FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
LZS3_k127_1392770_0	1183438.GKIL_1933	2.79e-161	537.0	COG0520@1|root,COG0520@2|Bacteria,1G15D@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
LZS3_k127_1392770_2	251221.35211938	1.127e-49	198.0	COG0822@1|root,COG0822@2|Bacteria,1G590@1117|Cyanobacteria	1117|Cyanobacteria	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
LZS3_k127_1400786_3	471852.Tcur_1029	1.06e-56	210.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4EHBK@85012|Streptosporangiales	201174|Actinobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
LZS3_k127_1400786_5	1125863.JAFN01000001_gene169	1.734e-26	115.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,42VYV@68525|delta/epsilon subdivisions,2WRGQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcription regulator MerR DNA binding	-	-	-	ko:K21902	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
LZS3_k127_1400786_1	1031711.RSPO_c03162	4.389e-88	316.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VGZU@28216|Betaproteobacteria,1K0VY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Dehydrogenase	paaH1	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
LZS3_k127_1400786_0	1254432.SCE1572_41455	8.108e-143	464.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2YUF5@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	bamN	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_1400786_2	1125863.JAFN01000001_gene573	1.301e-68	249.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
LZS3_k127_1400786_4	864563.HMPREF9166_0481	4.019e-47	178.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4H2IB@909932|Negativicutes	909932|Negativicutes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
LZS3_k127_1420120_1	1038858.AXBA01000002_gene3865	1.695e-24	119.0	COG1216@1|root,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,2U8FN@28211|Alphaproteobacteria,3F15B@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
LZS3_k127_1420120_0	861299.J421_2420	1.064e-85	294.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_1446709_1	671143.DAMO_2786	3.861e-17	85.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
LZS3_k127_1446709_0	1242864.D187_003593	1.095e-91	312.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2YU1B@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_1498540_0	1283299.AUKG01000002_gene4966	8.89e-116	392.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_1499179_1	1121438.JNJA01000004_gene646	2.178e-65	234.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MG1S@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
LZS3_k127_1499179_0	404589.Anae109_4145	2.103e-83	287.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YUTC@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS3_k127_1507264_2	1232437.KL662039_gene2065	1.486e-106	350.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MHPV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS3_k127_1507264_0	1125863.JAFN01000001_gene304	8.716e-157	502.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,42NWK@68525|delta/epsilon subdivisions,2WM2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
LZS3_k127_1507264_6	1280681.AUJZ01000013_gene1983	1.5e-79	284.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,4BW0I@830|Butyrivibrio	186801|Clostridia	E	ATPases associated with a variety of cellular activities	livF1	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
LZS3_k127_1507264_5	58123.JOFJ01000001_gene2973	9.427e-82	280.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4EIB3@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
LZS3_k127_1507264_4	1379698.RBG1_1C00001G1349	7.53e-86	308.0	COG4177@1|root,COG4177@2|Bacteria,2NPMP@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS3_k127_1507264_3	1122947.FR7_4232	1.669e-95	322.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4H29T@909932|Negativicutes	909932|Negativicutes	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
LZS3_k127_1507264_1	1379698.RBG1_1C00001G1351	1.295e-129	424.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS3_k127_1526238_1	1403819.BATR01000112_gene3805	5.579e-96	317.0	COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia,2ITM1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
LZS3_k127_1526238_3	880072.Desac_2383	2.142e-30	128.0	COG1226@1|root,32Y28@2|Bacteria,1PVKD@1224|Proteobacteria,4379F@68525|delta/epsilon subdivisions,2X2D3@28221|Deltaproteobacteria,2MSI0@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
LZS3_k127_1526238_0	460265.Mnod_2274	1.24e-223	708.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria,1JR06@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
LZS3_k127_1526238_2	398525.KB900701_gene4156	1.18e-71	254.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,2TTM8@28211|Alphaproteobacteria,3JW7P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
LZS3_k127_1552653_6	525368.HMPREF0591_0913	3.556e-32	133.0	2AU5M@1|root,31JSH@2|Bacteria,2IJSM@201174|Actinobacteria,239KJ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1552653_4	1207063.P24_03930	3.532e-78	270.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,2JRJC@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_1552653_3	1210884.HG799463_gene10045	1.162e-78	276.0	COG1253@1|root,COG1253@2|Bacteria,2IYEG@203682|Planctomycetes	203682|Planctomycetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
LZS3_k127_1552653_7	765869.BDW_08960	1.347e-14	86.0	2AIQT@1|root,3197J@2|Bacteria,1Q1ZE@1224|Proteobacteria,437MA@68525|delta/epsilon subdivisions,2MU3U@213481|Bdellovibrionales,2WYMC@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1552653_5	649638.Trad_1635	9.1e-67	246.0	COG0534@1|root,COG0534@2|Bacteria,1WKWJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	COGs COG0534 Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
LZS3_k127_1552653_1	1071679.BG57_16530	6.941e-121	414.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,1K01W@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
LZS3_k127_1552653_2	316055.RPE_4451	1.86e-108	381.0	COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,2TSHG@28211|Alphaproteobacteria,3K09N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
LZS3_k127_1552653_0	380358.XALC_2501	1.39e-122	403.0	COG2230@1|root,COG2230@2|Bacteria,1MUW5@1224|Proteobacteria,1RPUC@1236|Gammaproteobacteria,1X38D@135614|Xanthomonadales	135614|Xanthomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS3_k127_1552653_8	65497.JODV01000004_gene1500	6.888e-13	81.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria,4E2HK@85010|Pseudonocardiales	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	ko:K16431	ko01055,ko01059,ko01130,map01055,map01059,map01130	M00827,M00828,M00832	R11368,R11393	RC00949,RC03431	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
LZS3_k127_1581079_4	357808.RoseRS_2972	2.167e-39	150.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_1581079_0	383372.Rcas_1888	4.533e-122	406.0	COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi,3763W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_1581079_5	1499967.BAYZ01000118_gene3298	1.801e-13	83.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_25,Trm112p
LZS3_k127_1581079_2	58123.JOFJ01000006_gene240	4.483e-58	220.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4EGJA@85012|Streptosporangiales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
LZS3_k127_1581079_1	1382359.JIAL01000001_gene1927	1.297e-59	215.0	COG0745@1|root,COG0745@2|Bacteria,3Y4FA@57723|Acidobacteria,2JJ3P@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_1581079_3	1340493.JNIF01000003_gene3270	1.566e-53	201.0	COG5002@1|root,COG5002@2|Bacteria,3Y99C@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_1581079_6	420662.Mpe_A2269	2.902e-11	73.0	28J5I@1|root,2Z91C@2|Bacteria,1QVI2@1224|Proteobacteria,2VN9N@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
LZS3_k127_158951_1	1121861.KB899915_gene1809	8.384e-87	307.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JP9V@204441|Rhodospirillales	204441|Rhodospirillales	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS3_k127_158951_0	1131269.AQVV01000020_gene2195	3.407e-118	387.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	appC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS3_k127_1592510_1	1125863.JAFN01000001_gene292	1.071e-29	135.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
LZS3_k127_1592510_0	338963.Pcar_2579	1.178e-143	464.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,43S6R@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Aldehyde dehydrogenase family	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_1595090_0	448385.sce6663	1.412e-94	324.0	COG2267@1|root,COG2267@2|Bacteria,1MYEX@1224|Proteobacteria,43CP1@68525|delta/epsilon subdivisions,2X7WC@28221|Deltaproteobacteria,2Z2N6@29|Myxococcales	28221|Deltaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_1595090_2	290397.Adeh_3413	3.631e-59	226.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,42U1I@68525|delta/epsilon subdivisions,2WQQV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_core,Transglut_i_TM
LZS3_k127_1595090_1	713586.KB900536_gene1727	2.279e-65	255.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,1RR7D@1236|Gammaproteobacteria,1X01T@135613|Chromatiales	135613|Chromatiales	HJ	TIGRFAM alpha-L-glutamate ligase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
LZS3_k127_1599342_2	743719.PaelaDRAFT_4372	0.0002799	46.0	COG1082@1|root,COG1082@2|Bacteria,1TY9X@1239|Firmicutes,4I7DJ@91061|Bacilli,26WGF@186822|Paenibacillaceae	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_1599342_0	1463820.JOGW01000005_gene3336	8.199e-113	376.0	COG0111@1|root,COG0111@2|Bacteria,2GKN6@201174|Actinobacteria	201174|Actinobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_1599342_1	1260251.SPISAL_07880	4.265e-67	233.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,1X078@135613|Chromatiales	135613|Chromatiales	C	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
LZS3_k127_1626111_1	583355.Caka_2946	5.363e-38	163.0	COG0139@1|root,COG0139@2|Bacteria,46SZA@74201|Verrucomicrobia,3K7YM@414999|Opitutae	414999|Opitutae	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
LZS3_k127_1626111_0	1120950.KB892799_gene2145	1.372e-52	203.0	COG3119@1|root,COG3119@2|Bacteria,2IEA2@201174|Actinobacteria,4DWI5@85009|Propionibacteriales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_1626111_3	1123242.JH636435_gene1533	2.058e-27	115.0	COG2329@1|root,COG2329@2|Bacteria,2J0PW@203682|Planctomycetes	203682|Planctomycetes	S	enzyme involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
LZS3_k127_1626111_2	903818.KI912269_gene538	1.703e-34	150.0	COG1199@1|root,COG1199@2|Bacteria	2|Bacteria	L	ATP-dependent helicase activity	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
LZS3_k127_1629858_0	1210884.HG799475_gene15269	6.351e-243	762.0	COG0033@1|root,COG0033@2|Bacteria,2IYG0@203682|Planctomycetes	203682|Planctomycetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS3_k127_1629858_1	1192034.CAP_5764	1.835e-127	442.0	COG4690@1|root,COG4690@2|Bacteria,1RBRZ@1224|Proteobacteria	1224|Proteobacteria	E	dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
LZS3_k127_1640448_0	426117.M446_6162	3.676e-82	278.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,1JRJU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	MA20_36630	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
LZS3_k127_1640448_2	1048339.KB913029_gene4673	2.402e-17	95.0	2E8P5@1|root,3330B@2|Bacteria,2GRP1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1640448_1	1163408.UU9_08625	5.863e-59	214.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1X3ZV@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
LZS3_k127_1650564_1	344747.PM8797T_10429	1.073e-99	338.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS3_k127_1650564_0	1123368.AUIS01000003_gene1570	1.297e-124	424.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,1RNET@1236|Gammaproteobacteria,2ND4M@225057|Acidithiobacillales	225057|Acidithiobacillales	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
LZS3_k127_1655848_1	95619.PM1_0210770	2.445e-69	246.0	COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,1S58V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS3_k127_1655848_0	247633.GP2143_16891	2.261e-69	247.0	COG4990@1|root,COG4990@2|Bacteria,1MVC4@1224|Proteobacteria,1RS1H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
LZS3_k127_1660863_0	857087.Metme_2515	7.206e-33	149.0	COG1305@1|root,COG3209@1|root,COG1305@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SZFX@1236|Gammaproteobacteria,1XGJC@135618|Methylococcales	1236|Gammaproteobacteria	EM	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,Transglut_core
LZS3_k127_1678144_0	1123024.AUII01000012_gene4102	2.277e-84	289.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria,4E39N@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_1678144_1	1229780.BN381_410015	4.114e-63	224.0	COG0045@1|root,COG0045@2|Bacteria,2I3K9@201174|Actinobacteria	201174|Actinobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5
LZS3_k127_1692659_0	1179773.BN6_39980	1.148e-140	462.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DXK8@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS3_k127_1692659_1	1292373.H640_03473	0.0001884	47.0	COG1893@1|root,COG1893@2|Bacteria,2I3AM@201174|Actinobacteria,4DUY3@85009|Propionibacteriales	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS3_k127_1710273_1	391625.PPSIR1_20719	2.161e-33	140.0	COG1408@1|root,COG1408@2|Bacteria,1Q3AY@1224|Proteobacteria,43923@68525|delta/epsilon subdivisions,2X47Q@28221|Deltaproteobacteria,2YYFK@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_1710273_0	323261.Noc_2973	1.209e-111	380.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,1T2RV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam Transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1725519_0	391625.PPSIR1_01774	1.931e-218	691.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42QKW@68525|delta/epsilon subdivisions,2WKH1@28221|Deltaproteobacteria,2YWTQ@29|Myxococcales	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_1725519_1	1283299.AUKG01000002_gene4966	5.939e-46	172.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_1735820_3	221359.RS9916_38442	0.0005626	51.0	COG0438@1|root,COG0438@2|Bacteria,1GCNR@1117|Cyanobacteria,1GYNC@1129|Synechococcus	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
LZS3_k127_1735820_0	105559.Nwat_2381	3.649e-78	280.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1WXMD@135613|Chromatiales	135613|Chromatiales	GM	pfam abc	-	-	-	ko:K01990,ko:K09691	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC_tran,Wzt_C
LZS3_k127_1735820_2	1444711.CCJF01000005_gene621	5.504e-22	106.0	COG1682@1|root,COG1682@2|Bacteria,2JGGU@204428|Chlamydiae	204428|Chlamydiae	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
LZS3_k127_1735820_1	644282.Deba_0611	7.143e-69	244.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,42P3H@68525|delta/epsilon subdivisions,2WK0J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_1736503_0	1415780.JPOG01000001_gene2579	1.1e-124	422.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1X4DT@135614|Xanthomonadales	135614|Xanthomonadales	G	Na melibiose symporter and related transporters	ynaJ	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
LZS3_k127_1736503_2	68223.JNZY01000010_gene1991	5.871e-100	347.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA5	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_1736503_1	656024.FsymDg_2021	2.019e-117	382.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4ERHV@85013|Frankiales	201174|Actinobacteria	H	Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_1739793_2	631454.N177_0892	0.0006373	44.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria,1JNB6@119043|Rhodobiaceae	28211|Alphaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS3_k127_1739793_0	338966.Ppro_1343	6.476e-157	535.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
LZS3_k127_1739793_1	404589.Anae109_2111	2.892e-43	165.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2Z0ST@29|Myxococcales	28221|Deltaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
LZS3_k127_1742916_1	398767.Glov_1922	2.73e-39	165.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
LZS3_k127_1742916_0	1242864.D187_006569	2.45e-78	280.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,2YV0E@29|Myxococcales	28221|Deltaproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
LZS3_k127_1742916_2	290397.Adeh_0665	1.98e-29	127.0	2E2XW@1|root,32XYS@2|Bacteria,1N3ID@1224|Proteobacteria,42UFM@68525|delta/epsilon subdivisions,2WQKF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1743997_1	1122951.ATUE01000005_gene2162	2.411e-24	111.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,3NN8J@468|Moraxellaceae	1236|Gammaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
LZS3_k127_1743997_0	391625.PPSIR1_39025	6.352e-86	309.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,2YUQX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
LZS3_k127_1749651_0	215803.DB30_0854	4.478e-125	411.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2X1W0@28221|Deltaproteobacteria,2YUZR@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_1749651_1	671143.DAMO_2352	9.213e-81	291.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yeeZ	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
LZS3_k127_1749651_3	663932.KB902575_gene412	4.453e-35	156.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VG90@28211|Alphaproteobacteria,2JYRN@204441|Rhodospirillales	204441|Rhodospirillales	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
LZS3_k127_1749651_2	215803.DB30_3165	1.575e-66	248.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria,2YV5K@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_1749651_4	502025.Hoch_5602	1.937e-32	132.0	COG3011@1|root,COG3011@2|Bacteria,1N0YV@1224|Proteobacteria,42VUX@68525|delta/epsilon subdivisions,2WW8H@28221|Deltaproteobacteria,2Z1U7@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
LZS3_k127_1761687_1	247639.MGP2080_01155	2.299e-210	671.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1RMHR@1236|Gammaproteobacteria,1J7YQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2015 Alkyl sulfatase and related hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
LZS3_k127_1761687_3	237368.SCABRO_03600	4.363e-36	148.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1761687_2	754477.Q7C_308	9.889e-103	336.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,460A6@72273|Thiotrichales	72273|Thiotrichales	O	Alkyl hydroperoxide reductase	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
LZS3_k127_1761687_0	1095769.CAHF01000018_gene775	1.122e-218	691.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2VJ01@28216|Betaproteobacteria,473AQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Alkyl hydroperoxide reductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
LZS3_k127_1761687_4	1313172.YM304_12960	3.496e-31	129.0	COG2267@1|root,COG2267@2|Bacteria,2I79Z@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_1809814_0	864051.BurJ1DRAFT_3207	1.115e-97	348.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,2VQRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
LZS3_k127_1809814_2	1255043.TVNIR_0032	3.243e-08	65.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075,ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
LZS3_k127_1809814_1	557599.MKAN_25710	5.696e-92	306.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,234PM@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_1810662_3	1313172.YM304_13950	1.586e-35	150.0	COG4188@1|root,COG4188@2|Bacteria,2GZAJ@201174|Actinobacteria	201174|Actinobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
LZS3_k127_1810662_0	1121937.AUHJ01000003_gene3358	2.545e-167	542.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,1RQ1C@1236|Gammaproteobacteria,466HP@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_1810662_2	644282.Deba_0505	6.322e-69	253.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,42PZH@68525|delta/epsilon subdivisions,2WJ0T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
LZS3_k127_1810662_1	1174684.EBMC1_01405	4.098e-118	391.0	COG0412@1|root,COG0412@2|Bacteria,1PSEB@1224|Proteobacteria,2TTN4@28211|Alphaproteobacteria,2K4IX@204457|Sphingomonadales	204457|Sphingomonadales	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
LZS3_k127_1815130_1	1304874.JAFY01000002_gene335	6.873e-241	766.0	COG2943@1|root,COG2943@2|Bacteria,3TAHN@508458|Synergistetes	508458|Synergistetes	M	Glycosyl transferase family 21	-	-	-	ko:K03669	-	-	-	-	ko00000,ko01000,ko01003,ko02000	4.D.3.1.1	GT2	-	Glyco_trans_2_3,Glycos_transf_2
LZS3_k127_1815130_0	246197.MXAN_0988	0.0	1359.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
LZS3_k127_1815130_2	1283300.ATXB01000001_gene135	4.672e-91	309.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1XE3F@135618|Methylococcales	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23,HlyD_D4,YtkA
LZS3_k127_181796_0	35754.JNYJ01000003_gene6567	2.464e-138	450.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria,4DMI0@85008|Micromonosporales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_181796_1	290397.Adeh_0078	1.656e-37	149.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1846945_2	1379270.AUXF01000001_gene2608	3.264e-60	216.0	COG3597@1|root,COG3597@2|Bacteria	2|Bacteria	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	DUF533,DUF697,TerB
LZS3_k127_1846945_0	557599.MKAN_07990	2.31e-200	647.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,23361@1762|Mycobacteriaceae	201174|Actinobacteria	P	flavoprotein involved in K transport	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase,Pyr_redox_3
LZS3_k127_1846945_1	886293.Sinac_1559	3.784e-162	517.0	COG1132@1|root,COG1132@2|Bacteria,2IYCU@203682|Planctomycetes	2|Bacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
LZS3_k127_1849512_0	748247.AZKH_1882	1.944e-124	428.0	COG1231@1|root,COG1231@2|Bacteria,1P3D9@1224|Proteobacteria,2VPAN@28216|Betaproteobacteria,2KYE7@206389|Rhodocyclales	206389|Rhodocyclales	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS3_k127_1849512_4	945713.IALB_0196	1.549e-42	160.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,Haem_bd,PSD1
LZS3_k127_1849512_1	1415754.JQMK01000012_gene1033	1.062e-76	264.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,1RNXU@1236|Gammaproteobacteria,466HZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	ZIP Zinc transporter	zupT	GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	iECIAI39_1322.ECIAI39_3536	Zip
LZS3_k127_1849512_3	1192034.CAP_6619	1.842e-45	180.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,DLH
LZS3_k127_1849512_2	339670.Bamb_5833	3.247e-72	257.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2VH3I@28216|Betaproteobacteria,1K4JP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	hydrolase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS3_k127_1849512_5	643867.Ftrac_0043	1.948e-41	165.0	COG0457@1|root,COG0457@2|Bacteria,4NQY3@976|Bacteroidetes,47VUI@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
LZS3_k127_1849512_6	382464.ABSI01000006_gene844	7.206e-19	89.0	COG1704@1|root,COG1704@2|Bacteria,46V9M@74201|Verrucomicrobia,2IVY8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
LZS3_k127_1856012_3	330214.NIDE1740	1.233e-05	58.0	COG2251@1|root,COG2251@2|Bacteria	2|Bacteria	-	-	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF2779,HHH_5,KH_5,NusA_N,S1
LZS3_k127_1856012_2	370438.PTH_1997	1.057e-38	161.0	arCOG09742@1|root,2ZBGR@2|Bacteria,1V0RW@1239|Firmicutes,24AYH@186801|Clostridia,263KV@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1856012_0	414684.RC1_1522	1.866e-116	387.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,2JPTG@204441|Rhodospirillales	204441|Rhodospirillales	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
LZS3_k127_1856012_1	1122599.AUGR01000010_gene1086	7.602e-89	302.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1XJ0A@135619|Oceanospirillales	135619|Oceanospirillales	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
LZS3_k127_1865022_0	264462.Bd0967	1.652e-142	476.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42NID@68525|delta/epsilon subdivisions,2MSNJ@213481|Bdellovibrionales,2WJ4P@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
LZS3_k127_1865022_2	1254432.SCE1572_38255	4.157e-96	324.0	COG0278@1|root,COG0316@1|root,COG0607@1|root,COG0278@2|Bacteria,COG0316@2|Bacteria,COG0607@2|Bacteria,1MZ4V@1224|Proteobacteria,43154@68525|delta/epsilon subdivisions,2WWCI@28221|Deltaproteobacteria,2YVCT@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin,Rhodanese
LZS3_k127_1865022_3	502025.Hoch_5033	1.975e-10	68.0	COG0271@1|root,COG0271@2|Bacteria,1P2CW@1224|Proteobacteria,4353E@68525|delta/epsilon subdivisions,2X94Y@28221|Deltaproteobacteria,2Z1YU@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
LZS3_k127_1865022_1	391625.PPSIR1_32512	5.811e-136	443.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2YVBI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
LZS3_k127_188189_1	545276.KB898728_gene147	1.6e-08	65.0	2ERTY@1|root,33JD5@2|Bacteria,1NIJV@1224|Proteobacteria,1SIGE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4412
LZS3_k127_188189_0	502025.Hoch_2512	7.128e-12	73.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1903544_0	1499967.BAYZ01000026_gene1569	4.932e-274	856.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS3_k127_1903544_3	1128421.JAGA01000003_gene2832	3.1e-11	74.0	COG0071@1|root,COG0071@2|Bacteria,2NRTA@2323|unclassified Bacteria	2|Bacteria	O	Hsp20/alpha crystallin family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS3_k127_1903544_1	391625.PPSIR1_12563	7.65e-256	819.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS3_k127_1903544_2	1125863.JAFN01000001_gene972	1.895e-33	143.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
LZS3_k127_1919578_0	391625.PPSIR1_29720	1.515e-122	408.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YUCI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
LZS3_k127_1919578_1	909613.UO65_5824	1.495e-54	196.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria,4DZWK@85010|Pseudonocardiales	201174|Actinobacteria	EH	PFAM Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
LZS3_k127_1930775_0	765911.Thivi_1747	3.687e-120	412.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1WX9W@135613|Chromatiales	135613|Chromatiales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
LZS3_k127_1930775_1	118161.KB235922_gene2421	5.533e-38	150.0	COG0589@1|root,COG0589@2|Bacteria,1G75A@1117|Cyanobacteria,3VKQZ@52604|Pleurocapsales	1117|Cyanobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_1932456_3	330214.NIDE0342	6.764e-50	204.0	COG1305@1|root,COG1305@2|Bacteria,3J150@40117|Nitrospirae	40117|Nitrospirae	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,Transglut_core
LZS3_k127_1932456_2	448385.sce8272	6.472e-56	219.0	COG1721@1|root,COG1721@2|Bacteria,1N8IQ@1224|Proteobacteria,42S2K@68525|delta/epsilon subdivisions,2WNA2@28221|Deltaproteobacteria,2YVGE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS3_k127_1932456_0	1499967.BAYZ01000105_gene3512	4.128e-97	329.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS3_k127_1932456_4	861299.J421_2658	9.645e-41	165.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
LZS3_k127_1932456_5	1540221.JQNI01000002_gene741	2.183e-29	129.0	COG2264@1|root,COG2264@2|Bacteria,1WJ0S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
LZS3_k127_1932456_1	1357272.AVEO02000003_gene3736	3.428e-61	222.0	COG0451@1|root,COG0451@2|Bacteria,1MVPZ@1224|Proteobacteria,1SBJD@1236|Gammaproteobacteria,1Z9K8@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS3_k127_1936502_0	1125863.JAFN01000001_gene244	4.669e-133	448.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC transporter	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS3_k127_1936502_1	290397.Adeh_0078	1.395e-07	55.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1938654_2	1192034.CAP_2083	1.713e-06	60.0	COG0402@1|root,COG0402@2|Bacteria	2|Bacteria	F	S-adenosylhomocysteine deaminase activity	MA20_26585	-	3.5.2.18	ko:K01305,ko:K15358	ko00760,ko01120,map00760,map01120	-	R07984	RC01933	ko00000,ko00001,ko01000,ko01002	-	-	-	Amidohydro_1,Atu4866
LZS3_k127_1938654_1	1304877.KI519400_gene1366	5.798e-70	249.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2TSNX@28211|Alphaproteobacteria,3JQUD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Dehydrogenase	MA20_18560	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_1938654_0	1333998.M2A_2721	1.006e-105	358.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TRWW@28211|Alphaproteobacteria,4BR2E@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_1952064_0	502025.Hoch_6864	1.475e-187	600.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
LZS3_k127_1952064_1	1128421.JAGA01000003_gene2779	1.574e-116	407.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS3_k127_1956019_2	1348657.M622_02690	6.641e-72	250.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2VI6W@28216|Betaproteobacteria,2KUDQ@206389|Rhodocyclales	28216|Betaproteobacteria	C	Electron transfer flavoprotein alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
LZS3_k127_1956019_4	1348657.M622_02685	6.176e-32	130.0	COG1545@1|root,COG1545@2|Bacteria,1RIV9@1224|Proteobacteria	1224|Proteobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
LZS3_k127_1956019_0	1348657.M622_02680	2.304e-167	541.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2VM0D@28216|Betaproteobacteria,2KYPK@206389|Rhodocyclales	206389|Rhodocyclales	I	Thiolase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_1956019_1	1437824.BN940_14226	2.802e-125	421.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2VRSD@28216|Betaproteobacteria,3T726@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,DAO,NAD_binding_8
LZS3_k127_1956019_3	1313172.YM304_13620	9.907e-62	223.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_1956019_5	1120970.AUBZ01000064_gene3390	1.278e-09	66.0	COG2979@1|root,COG2979@2|Bacteria,1R95E@1224|Proteobacteria,1S2WZ@1236|Gammaproteobacteria,467M2@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF533)	yebE	-	-	-	-	-	-	-	-	-	-	-	DUF533
LZS3_k127_1963161_4	1122247.C731_2682	1.54e-20	102.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,233UW@1762|Mycobacteriaceae	201174|Actinobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS3_k127_1963161_1	517418.Ctha_2180	5.209e-120	402.0	COG1249@1|root,COG1249@2|Bacteria,1FDB4@1090|Chlorobi	1090|Chlorobi	C	pyridine nucleotide-disulphide oxidoreductase dimerisation region	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS3_k127_1963161_2	713587.THITH_10380	3.158e-66	234.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
LZS3_k127_1963161_3	526225.Gobs_4045	1.527e-43	170.0	COG1183@1|root,COG1183@2|Bacteria,2IC3M@201174|Actinobacteria	201174|Actinobacteria	I	phosphatidylcholine synthase	pcs	-	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS3_k127_1963161_0	215803.DB30_0835	3.143e-123	416.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,2YY0V@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
LZS3_k127_1967643_1	986075.CathTA2_3060	2.39e-27	124.0	COG1653@1|root,COG1653@2|Bacteria,1UM42@1239|Firmicutes	1239|Firmicutes	G	PFAM Bacterial extracellular solute-binding	-	-	-	ko:K17311	ko02010,map02010	M00604	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.15	-	-	SBP_bac_8
LZS3_k127_1967643_0	1380350.JIAP01000010_gene6100	4.047e-28	124.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TSH3@28211|Alphaproteobacteria,43NPQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	thuF	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
LZS3_k127_2018782_2	1158760.AQXP01000054_gene1578	1.34e-66	238.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales	135613|Chromatiales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
LZS3_k127_2018782_0	1232410.KI421418_gene2263	1.526e-85	304.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS3_k127_2018782_3	518766.Rmar_0010	2.08e-50	185.0	COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,1FJBB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
LZS3_k127_2018782_1	562970.Btus_1529	4.834e-76	271.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli,2787R@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
LZS3_k127_2018782_4	69042.WH5701_14321	1.084e-07	63.0	COG0743@1|root,COG0743@2|Bacteria,1G2CU@1117|Cyanobacteria,1GYKR@1129|Synechococcus	1117|Cyanobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
LZS3_k127_2049397_0	518766.Rmar_0138	7.751e-82	283.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1FIT8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS3_k127_2049397_1	518766.Rmar_0139	1.278e-48	194.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1FJ8V@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
LZS3_k127_2049397_2	1382306.JNIM01000001_gene3979	3.615e-13	72.0	COG1167@1|root,COG1167@2|Bacteria,2G5XE@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
LZS3_k127_205054_4	263358.VAB18032_04455	2.202e-18	94.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4DG1Z@85008|Micromonosporales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
LZS3_k127_205054_6	1122939.ATUD01000013_gene889	7.489e-13	78.0	COG0594@1|root,COG0594@2|Bacteria,2GR42@201174|Actinobacteria,4CQCA@84995|Rubrobacteria	84995|Rubrobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
LZS3_k127_205054_5	1357275.AVEL02000097_gene3418	3.694e-14	74.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
LZS3_k127_205054_3	269799.Gmet_0002	9.216e-103	346.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,43T1D@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
LZS3_k127_205054_1	398767.Glov_0004	1.745e-273	865.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
LZS3_k127_205054_0	1408254.T458_26210	4.39e-289	914.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,26SZ3@186822|Paenibacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS3_k127_205054_2	1385517.N800_02700	9.412e-154	532.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1X3C9@135614|Xanthomonadales	135614|Xanthomonadales	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_205054_7	522772.Dacet_0463	0.0003809	48.0	COG5336@1|root,COG5336@2|Bacteria,2GG0Q@200930|Deferribacteres	200930|Deferribacteres	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
LZS3_k127_2067276_0	502025.Hoch_1910	9.569e-102	341.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,42NHC@68525|delta/epsilon subdivisions,2WJQJ@28221|Deltaproteobacteria,2YUHD@29|Myxococcales	28221|Deltaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
LZS3_k127_2067276_1	926554.KI912616_gene4641	1.461e-51	194.0	COG0483@1|root,COG0483@2|Bacteria,1WN4P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
LZS3_k127_2067276_2	1123322.KB904634_gene2366	2.801e-45	174.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
LZS3_k127_2101983_0	1192034.CAP_7535	1.377e-142	462.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales	28221|Deltaproteobacteria	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
LZS3_k127_2101983_1	392499.Swit_0804	5.419e-60	224.0	COG2197@1|root,COG2197@2|Bacteria,1R2TM@1224|Proteobacteria,2TU4S@28211|Alphaproteobacteria,2K6MF@204457|Sphingomonadales	204457|Sphingomonadales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_2101983_2	1415779.JOMH01000001_gene2953	6.115e-37	158.0	COG4585@1|root,COG4585@2|Bacteria,1R1TC@1224|Proteobacteria,1S4C7@1236|Gammaproteobacteria,1X7VC@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM
LZS3_k127_2108571_2	1128421.JAGA01000003_gene3286	7.968e-40	160.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
LZS3_k127_2108571_0	1123368.AUIS01000007_gene2752	3.292e-154	514.0	COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,1RS00@1236|Gammaproteobacteria,2NCHK@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
LZS3_k127_2108571_3	314254.OA2633_04676	6.736e-14	85.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,43YKY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
LZS3_k127_2108571_1	518766.Rmar_2306	5.076e-76	271.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
LZS3_k127_2108571_4	945713.IALB_0844	0.0002067	52.0	COG0046@1|root,COG0046@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS3_k127_2111303_6	935866.JAER01000002_gene1912	4.945e-05	50.0	COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria	201174|Actinobacteria	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
LZS3_k127_2111303_2	251221.35214021	9.241e-46	171.0	COG0346@1|root,COG0346@2|Bacteria,1G5ZT@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_2111303_1	247633.GP2143_17626	7.229e-85	290.0	COG1028@1|root,COG1028@2|Bacteria,1R6DD@1224|Proteobacteria,1SYUP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_2111303_7	77586.LPERR08G10120.1	0.0002712	52.0	COG5641@1|root,KOG1601@2759|Eukaryota,37VIQ@33090|Viridiplantae,3GJR8@35493|Streptophyta,3M6VU@4447|Liliopsida,3IICN@38820|Poales	35493|Streptophyta	K	cytokinin-activated signaling pathway	-	-	-	ko:K14492	ko04075,map04075	-	-	-	ko00000,ko00001	-	-	-	Response_reg
LZS3_k127_2111303_0	661478.OP10G_4808	1.281e-119	407.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
LZS3_k127_2111303_4	479433.Caci_3580	5.414e-17	95.0	COG2755@1|root,COG2755@2|Bacteria,2GP5V@201174|Actinobacteria	201174|Actinobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Ricin_B_lectin
LZS3_k127_2111303_5	55529.EKX39833	9.32e-16	90.0	COG2363@1|root,KOG3472@2759|Eukaryota	2759|Eukaryota	J	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
LZS3_k127_2111303_3	1132509.C447_15131	2.484e-26	114.0	COG1208@1|root,arCOG00666@2157|Archaea,2XUA6@28890|Euryarchaeota,23SNR@183963|Halobacteria	183963|Halobacteria	M	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	graD4b	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS3_k127_2112037_2	661478.OP10G_1774	2.654e-10	71.0	2C7PP@1|root,33K9Q@2|Bacteria	2|Bacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	ko:K19295	-	-	-	-	ko00000	-	-	-	ALGX
LZS3_k127_2112037_0	1254432.SCE1572_06770	3.52e-162	528.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2WJ85@28221|Deltaproteobacteria,2Z32S@29|Myxococcales	28221|Deltaproteobacteria	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
LZS3_k127_2112037_1	1408418.JNJH01000008_gene2531	4.68e-57	209.0	COG3551@1|root,COG3551@2|Bacteria,1RB2G@1224|Proteobacteria,2U7MV@28211|Alphaproteobacteria,2JT3X@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2113477_1	1121448.DGI_2122	0.0003243	54.0	COG1807@1|root,COG1807@2|Bacteria,1NTFE@1224|Proteobacteria,42Z1W@68525|delta/epsilon subdivisions,2WTMJ@28221|Deltaproteobacteria,2M8VB@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_2113477_0	1217720.ALOX01000031_gene3762	1.453e-19	101.0	COG1835@1|root,COG1835@2|Bacteria,1N1UP@1224|Proteobacteria,2UCGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
LZS3_k127_2114944_0	1120948.KB903244_gene2941	3.524e-136	444.0	COG3616@1|root,COG3616@2|Bacteria,2GK0N@201174|Actinobacteria,4E1C7@85010|Pseudonocardiales	201174|Actinobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
LZS3_k127_2149155_2	452637.Oter_3284	7.061e-21	105.0	COG2909@1|root,COG3710@1|root,COG2909@2|Bacteria,COG3710@2|Bacteria,46UY3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	PFAM transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
LZS3_k127_2149155_0	82654.Pse7367_1114	9.847e-132	431.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria,1H8KG@1150|Oscillatoriales	1117|Cyanobacteria	M	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS3_k127_2149155_1	44454.NF84_19260	5.478e-80	275.0	COG2020@1|root,COG2020@2|Bacteria,2GN9N@201174|Actinobacteria,2336J@1762|Mycobacteriaceae	201174|Actinobacteria	O	NnrU protein	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU
LZS3_k127_215285_0	404589.Anae109_1884	7.132e-116	397.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
LZS3_k127_215285_1	1123253.AUBD01000006_gene788	5.784e-89	300.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1X40X@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
LZS3_k127_2153095_4	84531.JMTZ01000010_gene3185	1.252e-51	191.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,1X61F@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_2153095_3	309801.trd_0216	1.611e-63	234.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi,27XG5@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
LZS3_k127_2153095_0	1121861.KB899953_gene2383	5.446e-201	666.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,2TVN2@28211|Alphaproteobacteria,2JVBX@204441|Rhodospirillales	204441|Rhodospirillales	HP	MoeA C-terminal region (domain IV)	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
LZS3_k127_2153095_1	1192034.CAP_2432	3.595e-134	464.0	COG0303@1|root,COG0303@2|Bacteria	2|Bacteria	H	'Molybdopterin	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS3_k127_2153095_2	1125863.JAFN01000001_gene802	1.175e-131	441.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42MZJ@68525|delta/epsilon subdivisions,2WJK1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
LZS3_k127_2153095_5	547144.HydHO_0121	1.761e-11	68.0	COG1977@1|root,COG1977@2|Bacteria,2G563@200783|Aquificae	200783|Aquificae	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS3_k127_2183931_5	305900.GV64_19225	1.175e-39	168.0	COG1960@1|root,COG1960@2|Bacteria,1P4V3@1224|Proteobacteria,1RZBS@1236|Gammaproteobacteria,1XPUB@135619|Oceanospirillales	135619|Oceanospirillales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_2183931_0	83406.HDN1F_27440	2.711e-185	593.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPW2@1236|Gammaproteobacteria,1J4YX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_2183931_4	1472716.KBK24_0100785	3.894e-83	299.0	COG1024@1|root,COG1024@2|Bacteria,1PSRK@1224|Proteobacteria,2VKV4@28216|Betaproteobacteria,1K365@119060|Burkholderiaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_2183931_2	1121937.AUHJ01000006_gene2499	1.174e-117	404.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,1RPZN@1236|Gammaproteobacteria,469T4@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
LZS3_k127_2183931_3	298654.FraEuI1c_1921	5.425e-89	315.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4EWSD@85013|Frankiales	201174|Actinobacteria	H	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS3_k127_2183931_1	105425.BBPL01000024_gene350	1.46e-125	409.0	COG1788@1|root,COG1788@2|Bacteria,2GK61@201174|Actinobacteria,2NG4Q@228398|Streptacidiphilus	201174|Actinobacteria	I	Coenzyme A transferase	cotA	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS3_k127_2183931_6	1280941.HY2_13260	7.329e-38	152.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TUFX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.7	ko:K15868	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_2205908_1	1177928.TH2_05318	1.13e-06	52.0	COG5525@1|root,COG5525@2|Bacteria,1MVS3@1224|Proteobacteria,2TRW8@28211|Alphaproteobacteria,2JTCJ@204441|Rhodospirillales	204441|Rhodospirillales	L	COG5525 Bacteriophage tail assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_GpA
LZS3_k127_2205908_0	1415780.JPOG01000001_gene2508	8.432e-231	738.0	2DBUU@1|root,2ZB7U@2|Bacteria,1R8WF@1224|Proteobacteria,1SMN0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
LZS3_k127_2205908_2	395495.Lcho_4330	0.0005401	43.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2VJ1D@28216|Betaproteobacteria,1KN9R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Fibronectin type III-like domain	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
LZS3_k127_2208631_0	1232410.KI421420_gene3182	7.111e-253	799.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,43SCA@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TRCF	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
LZS3_k127_2208631_1	530564.Psta_3400	6.16e-33	143.0	COG0750@1|root,COG0793@1|root,COG2234@1|root,COG0750@2|Bacteria,COG0793@2|Bacteria,COG2234@2|Bacteria,2IXR2@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M28
LZS3_k127_222983_0	1121935.AQXX01000136_gene4063	4.13e-05	53.0	COG3117@1|root,COG3117@2|Bacteria,1NGCC@1224|Proteobacteria,1SGDP@1236|Gammaproteobacteria,1XMNP@135619|Oceanospirillales	135619|Oceanospirillales	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
LZS3_k127_2249987_0	1240349.ANGC01000009_gene2811	0.0	1251.0	COG4770@1|root,COG4799@1|root,COG4770@2|Bacteria,COG4799@2|Bacteria,2GIZP@201174|Actinobacteria,4FVN8@85025|Nocardiaceae	201174|Actinobacteria	I	Acetyl-CoA carboxylase, central region	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
LZS3_k127_2249987_1	1122236.KB905141_gene1204	1.391e-73	285.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,2KKEP@206350|Nitrosomonadales	206350|Nitrosomonadales	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
LZS3_k127_2254807_2	1122176.KB903538_gene1453	2.004e-12	78.0	COG1032@1|root,COG1032@2|Bacteria,4NH8Y@976|Bacteroidetes,1IRE5@117747|Sphingobacteriia	2|Bacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS3_k127_2254807_0	1094184.KWO_0108870	2.568e-43	173.0	COG0402@1|root,COG0402@2|Bacteria,1NFUA@1224|Proteobacteria,1TBWR@1236|Gammaproteobacteria,1X9DY@135614|Xanthomonadales	135614|Xanthomonadales	F	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS3_k127_2254807_1	204669.Acid345_2569	1.447e-17	89.0	298YX@1|root,2ZW2P@2|Bacteria	2|Bacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2255090_0	63737.Npun_R6387	4.164e-122	418.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1G45B@1117|Cyanobacteria,1HJ94@1161|Nostocales	1117|Cyanobacteria	PT	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
LZS3_k127_2255090_1	1469245.JFBG01000086_gene1610	8.903e-62	222.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,1T26M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Xanthine dehydrogenase	xdhB	GO:0000166,GO:0003674,GO:0003824,GO:0004854,GO:0005488,GO:0006139,GO:0006144,GO:0006145,GO:0006150,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009114,GO:0009987,GO:0016491,GO:0016725,GO:0016726,GO:0019439,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046100,GO:0046113,GO:0046483,GO:0046700,GO:0048037,GO:0050660,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071949,GO:0072521,GO:0072523,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575	1.17.1.4,1.3.99.8	ko:K13479,ko:K16878	ko00230,ko00365,ko01100,ko01120,map00230,map00365,map01100,map01120	M00546	R01768,R02103,R02987	RC00143,RC01856	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2444,iNRG857_1313.NRG857_14070,iS_1188.S3069	CO_deh_flav_C,FAD_binding_5
LZS3_k127_231401_0	1125863.JAFN01000001_gene3405	1.802e-88	311.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
LZS3_k127_231401_1	880072.Desac_2720	1.137e-72	251.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2MQF7@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
LZS3_k127_2332736_2	1123242.JH636434_gene4133	1.485e-32	140.0	COG1186@1|root,COG1186@2|Bacteria,2J05G@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
LZS3_k127_2332736_1	1120936.KB907210_gene5519	1.787e-116	381.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4EGKE@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_2332736_0	1219035.NT2_05_04640	8.978e-157	504.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2K2DM@204457|Sphingomonadales	204457|Sphingomonadales	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
LZS3_k127_2335823_2	269799.Gmet_2328	2.458e-32	130.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,43TKR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Stationary phase survival protein, YicC family, YicC_N and DUF1732 domain-containing	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
LZS3_k127_2335823_3	665942.HMPREF1022_00616	1.51e-26	111.0	COG2052@1|root,COG2052@2|Bacteria,1N0KP@1224|Proteobacteria,42TSK@68525|delta/epsilon subdivisions,2WQHH@28221|Deltaproteobacteria,2MCH0@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the UPF0296 family	-	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
LZS3_k127_2335823_1	768671.ThimaDRAFT_2735	7.496e-53	193.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1WY9P@135613|Chromatiales	135613|Chromatiales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
LZS3_k127_2335823_0	1192034.CAP_2384	6.828e-156	501.0	COG1899@1|root,COG1899@2|Bacteria,1MVC6@1224|Proteobacteria,4385P@68525|delta/epsilon subdivisions,2X9YE@28221|Deltaproteobacteria,2YUXU@29|Myxococcales	28221|Deltaproteobacteria	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
LZS3_k127_2336437_1	1123256.KB907927_gene1540	4.404e-80	271.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1X3E9@135614|Xanthomonadales	135614|Xanthomonadales	G	COG3459 Cellobiose phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
LZS3_k127_2336437_0	1442599.JAAN01000026_gene1170	2.814e-96	327.0	COG3408@1|root,COG3408@2|Bacteria,1QU1Q@1224|Proteobacteria,1RRX2@1236|Gammaproteobacteria,1X4YN@135614|Xanthomonadales	135614|Xanthomonadales	G	coagulation factor 5 8 type	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,F5_F8_type_C,GDE_C
LZS3_k127_2345595_3	1449048.JQKU01000021_gene1815	5.12e-40	153.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria,234CU@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_2345595_2	298654.FraEuI1c_2554	1.103e-84	301.0	COG0683@1|root,COG0683@2|Bacteria,2IAAV@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
LZS3_k127_2345595_0	365528.KB891240_gene6073	1.315e-115	384.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_2345595_4	1297742.A176_00410	2.013e-09	69.0	COG0793@1|root,COG3577@1|root,COG0793@2|Bacteria,COG3577@2|Bacteria,1N5HU@1224|Proteobacteria	1224|Proteobacteria	M	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,PDZ_2
LZS3_k127_2345595_5	794903.OPIT5_23720	5.286e-07	60.0	COG2374@1|root,COG2374@2|Bacteria,46YQE@74201|Verrucomicrobia,3KA00@414999|Opitutae	414999|Opitutae	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2345595_1	1123320.KB889562_gene6741	4.948e-98	324.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_2346115_1	1122247.C731_1920	1.621e-55	207.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,23F9C@1762|Mycobacteriaceae	201174|Actinobacteria	K	PFAM transcriptional regulator domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
LZS3_k127_2346115_3	435908.IDSA_06180	1.839e-11	78.0	COG3089@1|root,COG3089@2|Bacteria,1N6TM@1224|Proteobacteria,1SCDE@1236|Gammaproteobacteria,2QGER@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Belongs to the UPF0270 family	yheU	-	-	ko:K09898	-	-	-	-	ko00000	-	-	-	UPF0270
LZS3_k127_2346115_0	561175.KB894096_gene435	3.355e-230	725.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4EH87@85012|Streptosporangiales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
LZS3_k127_2346115_2	243233.MCA2966	1.405e-43	169.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1XEI4@135618|Methylococcales	135618|Methylococcales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
LZS3_k127_23495_0	582899.Hden_3175	2.053e-175	564.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
LZS3_k127_23495_1	63737.Npun_F1181	1.759e-10	63.0	COG0697@1|root,COG0697@2|Bacteria,1G29Y@1117|Cyanobacteria,1HKK6@1161|Nostocales	1117|Cyanobacteria	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_2358286_1	1206743.BAGM01000101_gene2583	1.144e-33	134.0	COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria,4G0CF@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
LZS3_k127_2358286_0	1229780.BN381_150017	1.28e-169	547.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,3UXGG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	NMO
LZS3_k127_2377673_1	391937.NA2_14832	3.718e-12	72.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2TVKC@28211|Alphaproteobacteria,43JFG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	MA20_22745	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
LZS3_k127_2377673_0	1458427.BAWN01000006_gene464	9.622e-213	684.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VK56@28216|Betaproteobacteria,4A9ZV@80864|Comamonadaceae	28216|Betaproteobacteria	CP	Na H antiporter MnhB subunit-related protein	-	-	-	ko:K05559,ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
LZS3_k127_2384705_2	390874.Tpet_1323	2.295e-06	54.0	COG1940@1|root,COG1940@2|Bacteria,2GCCT@200918|Thermotogae	200918|Thermotogae	G	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS3_k127_2384705_0	378806.STAUR_6565	2.812e-69	258.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
LZS3_k127_2384705_1	1161401.ASJA01000008_gene1626	5.661e-51	186.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,43WIJ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
LZS3_k127_2385998_2	1185876.BN8_04178	0.0006324	48.0	28TH6@1|root,2ZFR3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2385998_0	1288494.EBAPG3_3000	3.679e-19	96.0	2EFX2@1|root,339PA@2|Bacteria,1NGKD@1224|Proteobacteria,2VY14@28216|Betaproteobacteria,374HM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
LZS3_k127_2385998_1	335543.Sfum_3525	3.016e-10	65.0	COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria,42Z3E@68525|delta/epsilon subdivisions,2WU93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
LZS3_k127_2388342_0	1125863.JAFN01000001_gene1858	2.463e-91	317.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_2388342_1	1121949.AQXT01000002_gene2815	3.106e-91	319.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2TVI8@28211|Alphaproteobacteria,43XT1@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
LZS3_k127_2388342_2	1449350.OCH239_10510	0.0001945	46.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria	1224|Proteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
LZS3_k127_238934_1	402881.Plav_2700	4.469e-50	183.0	COG0494@1|root,COG0494@2|Bacteria,1NTFG@1224|Proteobacteria,2U0I4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Hydrolase	MA20_35615	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS3_k127_238934_0	886293.Sinac_4097	4.611e-54	212.0	COG3394@1|root,COG3394@2|Bacteria,2IWVW@203682|Planctomycetes	203682|Planctomycetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
LZS3_k127_238934_2	1519464.HY22_09520	2.618e-41	173.0	COG0483@1|root,COG0483@2|Bacteria,1FDDF@1090|Chlorobi	1090|Chlorobi	G	TIGRFAM histidinol-phosphate phosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
LZS3_k127_2400416_1	1121106.JQKB01000035_gene6092	3.546e-16	79.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,2TT6S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
LZS3_k127_2400416_0	1123393.KB891327_gene335	6.236e-169	542.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
LZS3_k127_2400995_0	234267.Acid_7035	1.252e-209	665.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS3_k127_2402079_2	1123392.AQWL01000006_gene656	4.348e-48	186.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,1KSX6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS3_k127_2402079_1	926550.CLDAP_04870	1.3e-124	431.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_2402079_4	1540221.JQNI01000002_gene1912	3.252e-24	115.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_2402079_0	794903.OPIT5_01950	2.325e-157	520.0	COG1055@1|root,COG1055@2|Bacteria,46S61@74201|Verrucomicrobia,3K7MJ@414999|Opitutae	414999|Opitutae	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
LZS3_k127_2402079_3	246196.MSMEI_0327	3.889e-38	149.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,23761@1762|Mycobacteriaceae	201174|Actinobacteria	I	Biotin carboxylase	-	-	6.4.1.3,6.4.1.4	ko:K01965,ko:K01968	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00036,M00373,M00741	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
LZS3_k127_2406520_2	1283300.ATXB01000001_gene2084	9.56e-70	245.0	COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,1S4WV@1236|Gammaproteobacteria,1XFER@135618|Methylococcales	135618|Methylococcales	M	Domain of unknown function (DUF4398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
LZS3_k127_2406520_4	290397.Adeh_0078	5.957e-18	95.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2406520_5	502025.Hoch_2512	7.473e-15	80.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2406520_1	1229780.BN381_60006	3.618e-146	488.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,3UXF8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
LZS3_k127_2406520_3	391625.PPSIR1_08202	9.822e-27	123.0	KOG1584@1|root,32BW5@2|Bacteria,1PW91@1224|Proteobacteria,42YNQ@68525|delta/epsilon subdivisions,2WTQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
LZS3_k127_2406520_0	1166018.FAES_1227	1.401e-174	571.0	COG0438@1|root,COG0438@2|Bacteria,4PKQN@976|Bacteroidetes,47K56@768503|Cytophagia	976|Bacteroidetes	M	PFAM glycogen synthase	-	-	2.4.1.11	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	-	R00292	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3	-	Glycogen_syn
LZS3_k127_2406520_6	1205680.CAKO01000037_gene1298	3.457e-14	78.0	COG0439@1|root,COG1038@1|root,COG4799@1|root,COG0439@2|Bacteria,COG1038@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2TWYZ@28211|Alphaproteobacteria,2JZ2C@204441|Rhodospirillales	204441|Rhodospirillales	I	Biotin carboxylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
LZS3_k127_2412404_0	1210884.HG799465_gene12267	1.126e-102	370.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,CarboxypepD_reg,IAT_beta,Invasin_D3,PPC
LZS3_k127_2412404_4	696747.NIES39_C00400	0.0001606	55.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4114,DUF5122,HemolysinCabind,Lectin_C,PPC,PQQ_2,P_proprotein,Peptidase_S8,SBBP,VCBS
LZS3_k127_2412404_1	251221.35212827	5.076e-54	205.0	2DMEM@1|root,32R0F@2|Bacteria,1GHES@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2412404_3	335543.Sfum_3623	1.957e-13	82.0	COG2374@1|root,COG2374@2|Bacteria,1NMB6@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2412404_2	357808.RoseRS_2348	2.098e-33	146.0	COG2885@1|root,COG5492@1|root,COG2885@2|Bacteria,COG5492@2|Bacteria,2GBMA@200795|Chloroflexi,377D0@32061|Chloroflexia	32061|Chloroflexia	M	Polymorphic membrane protein, Chlamydia	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2420523_0	56780.SYN_01427	5.97e-67	237.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42PIH@68525|delta/epsilon subdivisions,2WJH2@28221|Deltaproteobacteria,2MRI5@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
LZS3_k127_2420523_1	292459.STH1933	1.96e-54	211.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia	186801|Clostridia	HP	Abc transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
LZS3_k127_2420523_3	1504672.669784555	2.57e-09	61.0	COG2002@1|root,COG2002@2|Bacteria,1NBUR@1224|Proteobacteria	1224|Proteobacteria	K	transcriptional regulator, AbrB	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
LZS3_k127_2420523_2	370438.PTH_0499	5.682e-20	96.0	COG1848@1|root,COG1848@2|Bacteria,1VKNI@1239|Firmicutes,24VDB@186801|Clostridia,266AG@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS3_k127_2421034_0	702113.PP1Y_AT23375	1.962e-136	451.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,2K0DW@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
LZS3_k127_2445502_1	1411123.JQNH01000001_gene776	1.313e-102	345.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TS80@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CBS domain containing protein	tlyC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
LZS3_k127_2445502_0	1108045.GORHZ_075_00200	3.196e-142	461.0	COG5361@1|root,COG5361@2|Bacteria,2HES3@201174|Actinobacteria,4GH56@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
LZS3_k127_2445502_2	247634.GPB2148_3614	6.825e-96	327.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	GO:0003674,GO:0003824,GO:0005575,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016782,GO:0031224,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044425,GO:0046505,GO:0046506,GO:0071704,GO:1901576	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
LZS3_k127_245232_0	247634.GPB2148_2703	2.296e-108	362.0	COG0438@1|root,COG0438@2|Bacteria,1QW8R@1224|Proteobacteria	1224|Proteobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
LZS3_k127_245232_1	349521.HCH_03035	2.426e-18	100.0	COG2340@1|root,COG5640@1|root,COG2340@2|Bacteria,COG5640@2|Bacteria,1MZ84@1224|Proteobacteria,1S99N@1236|Gammaproteobacteria,1XKMP@135619|Oceanospirillales	135619|Oceanospirillales	O	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,PPC
LZS3_k127_2454093_2	1122604.JONR01000004_gene805	9.081e-32	128.0	COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,1RYCC@1236|Gammaproteobacteria,1X7WF@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_2454093_0	443218.AS9A_0960	2.929e-122	399.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,2335C@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_2454093_1	1463854.JOHT01000006_gene6755	8.894e-81	271.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	fadA6	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_2461646_0	1121013.P873_00375	2.537e-235	743.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,OmpA
LZS3_k127_2461646_4	1121013.P873_00380	8.175e-63	243.0	2C4KT@1|root,340PA@2|Bacteria,1NYVI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2461646_1	1121013.P873_00385	3.089e-217	691.0	COG0464@1|root,COG0464@2|Bacteria,1RCHW@1224|Proteobacteria	1224|Proteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
LZS3_k127_2461646_3	1380391.JIAS01000011_gene5180	8.852e-101	337.0	COG1842@1|root,COG1842@2|Bacteria,1NNUD@1224|Proteobacteria	1224|Proteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
LZS3_k127_2461646_2	357808.RoseRS_0765	3.101e-108	365.0	COG2124@1|root,COG2124@2|Bacteria,2G7SX@200795|Chloroflexi,3771I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_2470509_1	1122247.C731_1096	9.882e-91	318.0	COG0616@1|root,COG0616@2|Bacteria,2HQDG@201174|Actinobacteria,2358Q@1762|Mycobacteriaceae	201174|Actinobacteria	OU	signal peptide peptidase SppA, 67K type	sppA	-	-	ko:K04773,ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS3_k127_2470509_0	1095769.CAHF01000006_gene1763	7.367e-145	472.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2VIJB@28216|Betaproteobacteria,4724J@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_2491231_3	661478.OP10G_3205	6.796e-11	73.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
LZS3_k127_2491231_2	204669.Acid345_3527	6.513e-13	76.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_3527|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2491231_0	500153.JOEK01000003_gene847	2.271e-83	282.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria	201174|Actinobacteria	L	o-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2218,Methyltransf_3
LZS3_k127_2491231_1	264462.Bd3044	1.089e-16	81.0	COG2036@1|root,COG2036@2|Bacteria,1N3S6@1224|Proteobacteria,42UYX@68525|delta/epsilon subdivisions,2MU6K@213481|Bdellovibrionales,2WQE4@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	protein heterodimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2500102_2	502025.Hoch_2200	3.482e-36	158.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
LZS3_k127_2500102_0	330214.NIDE4040	6.771e-100	349.0	COG0247@1|root,COG1146@1|root,COG0247@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	glpC	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.1.5.3,1.2.7.3	ko:K00113,ko:K00176,ko:K05524,ko:K13795,ko:K13796	ko00020,ko00564,ko00720,ko01100,ko01110,ko01120,ko01200,map00020,map00564,map00720,map01100,map01110,map01120,map01200	M00009,M00011,M00173,M00620	R00848,R01197	RC00004,RC00029,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,DUF3470,DUF3501,Fer4,Fer4_8
LZS3_k127_2500102_3	876269.ARWA01000001_gene1282	4.539e-16	78.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2U5EA@28211|Alphaproteobacteria,3NBYW@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS3_k127_2500102_1	502025.Hoch_2201	4.727e-48	176.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2YV2V@29|Myxococcales	28221|Deltaproteobacteria	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
LZS3_k127_2500439_0	1541065.JRFE01000026_gene2195	2.468e-60	227.0	COG1028@1|root,COG1028@2|Bacteria,1GCUE@1117|Cyanobacteria,3VM0W@52604|Pleurocapsales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_2500439_1	243231.GSU3376	5.784e-37	148.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria,43V13@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
LZS3_k127_2501359_2	1123377.AUIV01000005_gene1739	1.918e-55	202.0	COG1262@1|root,COG1262@2|Bacteria,1RAP4@1224|Proteobacteria,1RQ7C@1236|Gammaproteobacteria,1X5A7@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS3_k127_2501359_3	1384054.N790_02820	1.925e-33	145.0	COG1999@1|root,COG1999@2|Bacteria,1N5E3@1224|Proteobacteria,1SEFK@1236|Gammaproteobacteria,1X6YE@135614|Xanthomonadales	135614|Xanthomonadales	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS3_k127_2501359_1	448385.sce7568	8.157e-84	288.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,42SG1@68525|delta/epsilon subdivisions,2WP1E@28221|Deltaproteobacteria,2YUU8@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
LZS3_k127_2501359_0	335543.Sfum_2676	1.091e-169	562.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MR6F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
LZS3_k127_2502423_1	113395.AXAI01000002_gene5235	9.778e-56	212.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,3JWDH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_2502423_0	1333998.M2A_2551	6.945e-110	370.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRIH@28211|Alphaproteobacteria,4BQEZ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	MA20_16365	-	4.2.1.149	ko:K08299	-	-	R10675	RC01095	ko00000,ko01000	-	-	-	ECH_1
LZS3_k127_2502423_2	1469607.KK073768_gene4395	6.008e-10	69.0	COG4113@1|root,COG4113@2|Bacteria,1G6NY@1117|Cyanobacteria,1HPH0@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS3_k127_2507197_4	553385.JEMF01000047_gene3323	4.119e-07	54.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1XHW3@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
LZS3_k127_2507197_2	227377.CBU_1323	6.687e-38	145.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1JEHD@118969|Legionellales	118969|Legionellales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
LZS3_k127_2507197_3	1408823.AXUS01000006_gene7	5.547e-10	64.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,25RWU@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
LZS3_k127_2507197_1	1158318.ATXC01000001_gene271	1.417e-49	186.0	COG0290@1|root,COG0290@2|Bacteria,2G432@200783|Aquificae	200783|Aquificae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
LZS3_k127_2507197_0	1121920.AUAU01000033_gene2756	9.482e-201	646.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
LZS3_k127_251098_1	1449069.JMLO01000015_gene647	2.86e-162	532.0	COG2937@1|root,COG2937@2|Bacteria,2GMQF@201174|Actinobacteria,4FWRE@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_251098_2	383372.Rcas_1854	1.775e-36	158.0	COG2343@1|root,COG2343@2|Bacteria,2G79F@200795|Chloroflexi,377I0@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
LZS3_k127_251098_0	118166.JH976537_gene4640	3.261e-217	693.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1G40A@1117|Cyanobacteria,1HI0P@1150|Oscillatoriales	1117|Cyanobacteria	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
LZS3_k127_251522_1	1120934.KB894415_gene3946	1.073e-79	277.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4E0AR@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_251522_4	797209.ZOD2009_13251	7.914e-36	144.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2XY9V@28890|Euryarchaeota,23W96@183963|Halobacteria	183963|Halobacteria	S	Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
LZS3_k127_251522_2	243231.GSU2320	1.609e-48	183.0	COG3572@1|root,COG3572@2|Bacteria	2|Bacteria	H	ergothioneine biosynthetic process	-	-	6.3.2.2	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
LZS3_k127_251522_0	483219.LILAB_15970	5.731e-118	402.0	COG1232@1|root,COG1232@2|Bacteria,1R7EY@1224|Proteobacteria	1224|Proteobacteria	H	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS3_k127_251522_3	502025.Hoch_2213	1.686e-37	161.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,43AJU@68525|delta/epsilon subdivisions,2X600@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,MerR_1
LZS3_k127_2517860_0	237368.SCABRO_03724	1.642e-189	605.0	COG1389@1|root,COG1389@2|Bacteria,2J2A8@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
LZS3_k127_2517860_1	237368.SCABRO_03725	4.466e-158	508.0	COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
LZS3_k127_2517860_2	251221.35211030	1.063e-119	409.0	COG1209@1|root,COG1209@2|Bacteria,1G091@1117|Cyanobacteria	1117|Cyanobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS3_k127_2517860_4	1123368.AUIS01000003_gene1679	4.467e-60	226.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,2NCIQ@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
LZS3_k127_2517860_3	1123242.JH636434_gene4425	4.067e-77	278.0	COG1028@1|root,COG1028@2|Bacteria,2IYKS@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_2520474_3	378806.STAUR_3121	5.251e-60	228.0	COG0807@1|root,COG0807@2|Bacteria,1QZI6@1224|Proteobacteria,43CJ9@68525|delta/epsilon subdivisions,2X7TM@28221|Deltaproteobacteria,2Z35A@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	-	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
LZS3_k127_2520474_2	316058.RPB_3598	9.445e-85	291.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2TSSU@28211|Alphaproteobacteria,3JTWK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	MA20_16345	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_2520474_1	402881.Plav_3077	1.153e-88	307.0	28M2T@1|root,2ZAH6@2|Bacteria,1R6GW@1224|Proteobacteria,2U25T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2520474_0	1192034.CAP_3447	1.655e-104	353.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,42RUS@68525|delta/epsilon subdivisions,2WNWT@28221|Deltaproteobacteria,2YWXA@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
LZS3_k127_2530868_0	497964.CfE428DRAFT_4095	2.909e-178	580.0	COG1696@1|root,COG1696@2|Bacteria,46TUI@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM membrane bound O-acyl transferase MBOAT family protein	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
LZS3_k127_2530868_1	1254432.SCE1572_18520	1.461e-49	181.0	COG2267@1|root,COG2267@2|Bacteria,1QZUV@1224|Proteobacteria	1224|Proteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2536212_0	1211115.ALIQ01000030_gene2227	1.987e-176	581.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,3NAT0@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.321	ko:K13688,ko:K18786	-	-	R10832	RC00397	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
LZS3_k127_2540151_2	1123320.KB889585_gene1873	6.978e-44	165.0	COG1960@1|root,COG1960@2|Bacteria,2GK9C@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE27	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_2540151_0	1123320.KB889585_gene1872	9.364e-164	524.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_2540151_1	1123320.KB889562_gene6832	1.684e-50	185.0	COG2141@1|root,COG2141@2|Bacteria,2IB78@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_2545269_3	292459.STH1952	1.558e-30	130.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
LZS3_k127_2545269_0	247634.GPB2148_1995	3.383e-75	267.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RY4R@1236|Gammaproteobacteria,1J7ZG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	adh	-	1.1.1.303,1.1.1.4	ko:K00004	ko00650,map00650	-	R02855,R02946,R10504	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
LZS3_k127_2545269_2	1123072.AUDH01000029_gene1042	1.927e-50	186.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,2JRTF@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
LZS3_k127_2545269_1	378806.STAUR_4753	8.026e-68	235.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS3_k127_255235_0	768671.ThimaDRAFT_4173	2.821e-92	309.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
LZS3_k127_255235_1	765911.Thivi_4548	4.31e-51	190.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1WY34@135613|Chromatiales	135613|Chromatiales	S	pfam ammecr1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
LZS3_k127_255235_2	1047013.AQSP01000095_gene2301	8.78e-06	56.0	2DS9E@1|root,32VU1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_255859_0	448385.sce5497	1.543e-197	636.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,42Q4K@68525|delta/epsilon subdivisions,2WKQ1@28221|Deltaproteobacteria,2Z1M7@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase type-B family	polB	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
LZS3_k127_255859_1	1380387.JADM01000004_gene3004	4.462e-129	422.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1XIDG@135619|Oceanospirillales	135619|Oceanospirillales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
LZS3_k127_255859_2	869210.Marky_0500	8.807e-95	326.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_2565815_2	502025.Hoch_1713	5.46e-08	55.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
LZS3_k127_2565815_0	509190.Cseg_3784	5.407e-26	121.0	COG2267@1|root,COG2267@2|Bacteria,1N8UK@1224|Proteobacteria,2U35V@28211|Alphaproteobacteria,2KG36@204458|Caulobacterales	204458|Caulobacterales	I	PFAM alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
LZS3_k127_2565815_1	926550.CLDAP_22580	6.526e-18	97.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
LZS3_k127_2566940_0	861299.J421_3048	4.121e-294	924.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
LZS3_k127_256818_2	671143.DAMO_1390	2.085e-08	59.0	COG0742@1|root,COG0742@2|Bacteria,2NPTA@2323|unclassified Bacteria	2|Bacteria	L	Conserved hypothetical protein 95	rsmD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
LZS3_k127_256818_1	497964.CfE428DRAFT_3893	9.022e-50	183.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS3_k127_256818_0	396588.Tgr7_0102	3.791e-105	356.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
LZS3_k127_2568491_1	1121904.ARBP01000013_gene393	2.022e-16	88.0	COG4784@1|root,COG4784@2|Bacteria,4PM59@976|Bacteroidetes,47MK2@768503|Cytophagia	976|Bacteroidetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_2568491_0	383372.Rcas_1705	3.833e-102	351.0	COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_2570348_1	1147.D082_18440	1.128e-190	603.0	COG0017@1|root,COG0017@2|Bacteria,1G015@1117|Cyanobacteria,1H4FG@1142|Synechocystis	1117|Cyanobacteria	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS3_k127_2570348_6	926554.KI912640_gene1380	1.197e-22	107.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	ttgR	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
LZS3_k127_2570348_5	497321.C664_04966	1.427e-46	188.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,2KVQF@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
LZS3_k127_2570348_0	378806.STAUR_4411	3.77e-221	738.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX7V@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
LZS3_k127_2570348_2	656024.FsymDg_0509	1.436e-174	553.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4ESAE@85013|Frankiales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.24,4.1.3.25	ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200	M00346,M00373,M00376	R00237,R00473,R00934	RC00307,RC00308,RC00311,RC00407,RC00502,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
LZS3_k127_2570348_4	247633.GP2143_17996	9.837e-68	241.0	COG0346@1|root,COG0346@2|Bacteria,1MW8Z@1224|Proteobacteria	1224|Proteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
LZS3_k127_2570348_3	298653.Franean1_2322	4.48e-70	257.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4ESZE@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_2580605_4	861299.J421_1179	5.31e-32	128.0	COG1079@1|root,COG1079@2|Bacteria,1ZSUD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
LZS3_k127_2580605_0	1313172.YM304_24680	1.343e-118	398.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS3_k127_2580605_6	290397.Adeh_0078	1.61e-19	102.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2580605_1	172088.AUGA01000010_gene1565	2.86e-113	377.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,3JU10@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
LZS3_k127_2580605_3	448385.sce2780	3.113e-37	146.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2Z1SG@29|Myxococcales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS3_k127_2580605_2	909663.KI867150_gene2735	1.966e-73	250.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2MRAR@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS3_k127_2587880_3	1500257.JQNM01000002_gene4825	9.171e-12	71.0	COG4671@1|root,COG4671@2|Bacteria,1NE6T@1224|Proteobacteria,2U08G@28211|Alphaproteobacteria,4B7JS@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	glycosyl transferase	redA	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
LZS3_k127_2587880_5	446466.Cfla_0393	4.934e-05	54.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,4F24J@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
LZS3_k127_2587880_4	882086.SacxiDRAFT_0264	4.111e-11	74.0	2FI2W@1|root,349VN@2|Bacteria,2IRHN@201174|Actinobacteria,4E7PJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2587880_2	1120966.AUBU01000002_gene2099	9.573e-22	111.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_2587880_1	756067.MicvaDRAFT_2450	5.261e-46	188.0	COG0438@1|root,COG0457@1|root,COG0463@1|root,COG2518@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0463@2|Bacteria,COG2518@2|Bacteria,1GR5V@1117|Cyanobacteria	1117|Cyanobacteria	H	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11,Methyltransf_21
LZS3_k127_2587880_0	713586.KB900536_gene1954	6.235e-143	471.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1SAC7@1236|Gammaproteobacteria,1X121@135613|Chromatiales	135613|Chromatiales	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS3_k127_2588670_7	335543.Sfum_2922	4.184e-05	57.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS3_k127_2588670_1	1380394.JADL01000007_gene4528	2.247e-146	474.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,2JPTH@204441|Rhodospirillales	204441|Rhodospirillales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS3_k127_2588670_5	118173.KB235914_gene2476	1.543e-39	156.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_2588670_0	402881.Plav_2593	2.993e-208	677.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,1JPPK@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
LZS3_k127_2588670_3	113395.AXAI01000008_gene1102	4.296e-120	412.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,2U1M9@28211|Alphaproteobacteria,3JWED@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
LZS3_k127_2588670_2	113395.AXAI01000008_gene1103	1.293e-142	476.0	COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria,2U06R@28211|Alphaproteobacteria,3JRXQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
LZS3_k127_2588670_4	1335757.SPICUR_08865	4.5e-95	329.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Acyl-CoA synthetase (NDP forming)	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
LZS3_k127_2603416_1	1121918.ARWE01000001_gene2578	1.757e-64	230.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,42RV7@68525|delta/epsilon subdivisions,2WNZT@28221|Deltaproteobacteria,43RZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Kinase/pyrophosphorylase	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
LZS3_k127_2603416_0	717605.Theco_2421	0.0	1059.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,26QCH@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
LZS3_k127_2603416_2	234267.Acid_7374	7.698e-25	107.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ABM
LZS3_k127_2608631_0	243231.GSU2079	4.982e-158	518.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Penicillin-binding protein 2	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
LZS3_k127_2614241_3	1278073.MYSTI_07697	9.065e-35	148.0	2C36Y@1|root,331F9@2|Bacteria,1P3S7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2614241_0	1229780.BN381_30038	4.965e-98	332.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2614241_2	1449069.JMLO01000008_gene3497	3.73e-76	279.0	COG1028@1|root,COG1028@2|Bacteria,2GMAG@201174|Actinobacteria,4FU2T@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_2614241_1	324057.Pjdr2_2579	6.074e-93	325.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	gtfB	GO:0005575,GO:0005576	2.4.1.5	ko:K00689	ko00500,ko02020,map00500,map02020	-	R02120,R06066	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,CW_binding_1,Glyco_hydro_70
LZS3_k127_2627630_1	497964.CfE428DRAFT_4096	1.271e-17	89.0	2D25X@1|root,32TC5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2627630_0	316067.Geob_2145	2.61e-200	644.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,43SZI@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
LZS3_k127_2628827_0	640511.BC1002_0514	9.578e-109	366.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1K2VU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS3_k127_2628827_1	317619.ANKN01000228_gene970	1.815e-05	49.0	COG1215@1|root,COG3222@1|root,COG1215@2|Bacteria,COG3222@2|Bacteria,1GDJY@1117|Cyanobacteria,1MKT4@1212|Prochloraceae	1117|Cyanobacteria	M	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_2629694_3	1234364.AMSF01000005_gene730	1.399e-49	181.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,1S67S@1236|Gammaproteobacteria,1X75K@135614|Xanthomonadales	135614|Xanthomonadales	E	Lactoylglutathione lyase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_2629694_2	1121920.AUAU01000022_gene2498	1.277e-69	244.0	COG2518@1|root,COG2518@2|Bacteria,3Y5EB@57723|Acidobacteria	57723|Acidobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	PCMT
LZS3_k127_2629694_4	1033802.SSPSH_000666	1.736e-43	169.0	2A4CF@1|root,30SY3@2|Bacteria,1RFXP@1224|Proteobacteria,1SP3W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2629694_1	1304872.JAGC01000003_gene2351	1.264e-79	281.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMQ@68525|delta/epsilon subdivisions,2X6ZS@28221|Deltaproteobacteria,2M8YU@213115|Desulfovibrionales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS3_k127_2629694_0	1394178.AWOO02000016_gene6820	2.141e-196	622.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EFMP@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS3_k127_2634528_0	1316936.K678_05498	1.898e-07	63.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2TUKE@28211|Alphaproteobacteria,2JS30@204441|Rhodospirillales	204441|Rhodospirillales	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
LZS3_k127_2635262_2	709032.Sulku_0782	9.922e-13	73.0	COG1704@1|root,COG1704@2|Bacteria,1N0DU@1224|Proteobacteria,43B6Y@68525|delta/epsilon subdivisions,2YPB4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
LZS3_k127_2635262_1	497964.CfE428DRAFT_2480	1.588e-44	169.0	2AEIE@1|root,314DU@2|Bacteria,46WQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2635262_0	1229780.BN381_400016	2.916e-45	169.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_2635550_3	290397.Adeh_2480	1.272e-44	166.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
LZS3_k127_2635550_7	1139996.OMQ_01893	9.442e-12	73.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli,4B081@81852|Enterococcaceae	91061|Bacilli	D	DivIVA protein	divIVA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
LZS3_k127_2635550_8	1123501.KB902316_gene3006	8.807e-05	55.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
LZS3_k127_2635550_6	765913.ThidrDRAFT_0855	1.351e-12	77.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria,1WYXS@135613|Chromatiales	135613|Chromatiales	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
LZS3_k127_2635550_2	404589.Anae109_2522	9.137e-117	390.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
LZS3_k127_2635550_4	1125863.JAFN01000001_gene1140	7.381e-43	171.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
LZS3_k127_2635550_1	404589.Anae109_2524	9.426e-135	444.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria,2YYEJ@29|Myxococcales	28221|Deltaproteobacteria	F	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS3_k127_2635550_0	671143.DAMO_0707	1.237e-198	652.0	COG1003@1|root,COG1003@2|Bacteria,2NNSG@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
LZS3_k127_2635550_5	1121434.AULY01000006_gene409	8.791e-37	162.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,2M953@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
LZS3_k127_2636901_0	330214.NIDE1740	8.538e-81	285.0	COG2251@1|root,COG2251@2|Bacteria	2|Bacteria	-	-	nusA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF2779,HHH_5,KH_5,NusA_N,S1
LZS3_k127_2636901_1	1123355.JHYO01000031_gene1566	9.458e-11	74.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,2UK9W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2639214_0	1333998.M2A_2016	1.221e-191	611.0	COG2072@1|root,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,2TRG4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,Pyr_redox_3
LZS3_k127_2639214_1	903818.KI912268_gene1318	2.724e-186	618.0	COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
LZS3_k127_2639214_2	639030.JHVA01000001_gene519	2.526e-100	357.0	COG0580@1|root,COG0580@2|Bacteria,3Y3SK@57723|Acidobacteria,2JHX3@204432|Acidobacteriia	204432|Acidobacteriia	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
LZS3_k127_2639214_3	247634.GPB2148_1669	2.967e-46	189.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPM3@1236|Gammaproteobacteria,1JBRD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Sulfatase	ydeN	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
LZS3_k127_2641055_0	1120936.KB907216_gene3853	0.0	1275.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4EHHS@85012|Streptosporangiales	201174|Actinobacteria	C	2-oxoglutarate dehydrogenase C-terminal	kgd	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
LZS3_k127_2641055_3	706587.Desti_2057	3.097e-32	130.0	COG1598@1|root,COG1598@2|Bacteria,1RIRX@1224|Proteobacteria,42W3D@68525|delta/epsilon subdivisions,2WRPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
LZS3_k127_2641055_4	573370.DMR_04540	1.998e-21	97.0	COG1724@1|root,COG1724@2|Bacteria,1N7S3@1224|Proteobacteria,432J7@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
LZS3_k127_2641055_6	502025.Hoch_2512	3.719e-07	60.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2641055_5	1379270.AUXF01000007_gene972	1.84e-08	60.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	AhpC-TSA,Redoxin
LZS3_k127_2641055_1	1121013.P873_04940	2.318e-198	622.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1RNQ4@1236|Gammaproteobacteria,1X3UT@135614|Xanthomonadales	135614|Xanthomonadales	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	adhC	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_2641055_2	1510531.JQJJ01000004_gene4626	8.205e-89	304.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,3JSMX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA thioesterase	tesB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
LZS3_k127_2641055_7	502025.Hoch_6864	0.0006879	45.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
LZS3_k127_2647617_1	1382356.JQMP01000004_gene561	9.759e-11	68.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,27XPZ@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_2647617_0	1205753.A989_00090	2.457e-39	156.0	COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS3_k127_2647617_2	292459.STH2650	1.459e-08	68.0	COG3595@1|root,COG3595@2|Bacteria,1VB9T@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
LZS3_k127_267968_1	1140.Synpcc7942_0467	6.225e-07	61.0	COG5549@1|root,COG5549@2|Bacteria,1G4CD@1117|Cyanobacteria,1H0BQ@1129|Synechococcus	1117|Cyanobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
LZS3_k127_267968_0	1051632.TPY_1815	2.85e-103	350.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfaG	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	iSDY_1059.SDY_4061	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_2680808_2	754252.PFREUD_03340	1.922e-56	212.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DQX3@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
LZS3_k127_2680808_1	1123371.ATXH01000003_gene1979	2.225e-171	560.0	COG0137@1|root,COG0137@2|Bacteria,2GGZY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
LZS3_k127_2680808_9	1266909.AUAG01000002_gene1304	6.452e-05	55.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9
LZS3_k127_2680808_7	290397.Adeh_2688	2.464e-11	77.0	2DHU7@1|root,300Z2@2|Bacteria,1Q940@1224|Proteobacteria,433U6@68525|delta/epsilon subdivisions,2X3GR@28221|Deltaproteobacteria,2YW0V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
LZS3_k127_2680808_0	335543.Sfum_1036	3.778e-204	653.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2MR7D@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS3_k127_2680808_4	1278073.MYSTI_03474	2.925e-22	110.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,1MVIW@1224|Proteobacteria,43C2N@68525|delta/epsilon subdivisions,2X7D8@28221|Deltaproteobacteria,2YVWI@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_8
LZS3_k127_2680808_5	380394.Lferr_0674	1.057e-17	91.0	2DQEC@1|root,336A8@2|Bacteria,1NDSR@1224|Proteobacteria,1SI3R@1236|Gammaproteobacteria,2NDVU@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
LZS3_k127_2680808_3	768671.ThimaDRAFT_4375	1.165e-24	104.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,1WZ7T@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
LZS3_k127_2680808_6	697281.Mahau_0201	1.965e-12	76.0	COG1708@1|root,COG1708@2|Bacteria,1VCPX@1239|Firmicutes,24PE0@186801|Clostridia,42H2N@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM DNA polymerase beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
LZS3_k127_2680808_8	1090318.ATTI01000001_gene3095	2.662e-05	48.0	COG4118@1|root,COG4118@2|Bacteria,1NME9@1224|Proteobacteria,2UMMS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
LZS3_k127_2697479_1	290397.Adeh_3956	4.984e-22	101.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2697479_0	381666.H16_B0673	2.214e-54	197.0	COG1028@1|root,COG1028@2|Bacteria,1P48D@1224|Proteobacteria,2VQPV@28216|Betaproteobacteria,1KFSX@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.357	ko:K19811	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
LZS3_k127_2701795_1	378806.STAUR_3118	4.473e-12	75.0	2EQIM@1|root,33I4N@2|Bacteria,1NJZ4@1224|Proteobacteria,42XX4@68525|delta/epsilon subdivisions,2WST7@28221|Deltaproteobacteria,2YZ1I@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
LZS3_k127_2701795_2	502025.Hoch_3125	0.00074	52.0	2A5Z5@1|root,30URA@2|Bacteria,1PVG3@1224|Proteobacteria,434XN@68525|delta/epsilon subdivisions,2WZ8E@28221|Deltaproteobacteria,2Z1JW@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2701795_0	292459.STH463	1.562e-95	322.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia	186801|Clostridia	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS3_k127_271202_0	760568.Desku_1651	1.529e-138	457.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
LZS3_k127_273138_5	502025.Hoch_2213	3.025e-18	93.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,43AJU@68525|delta/epsilon subdivisions,2X600@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,MerR_1
LZS3_k127_273138_3	84588.SYNW0759	1.378e-31	146.0	COG0652@1|root,COG0652@2|Bacteria,1G3Y9@1117|Cyanobacteria,1H3G4@1129|Synechococcus	1117|Cyanobacteria	G	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802,ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Cadherin,HemolysinCabind,Pro_isomerase
LZS3_k127_273138_0	338969.Rfer_3895	4.749e-242	767.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria	28216|Betaproteobacteria	G	alpha-glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
LZS3_k127_273138_2	1123257.AUFV01000008_gene763	1.589e-75	264.0	COG3752@1|root,COG3752@2|Bacteria,1R4MV@1224|Proteobacteria,1S0DP@1236|Gammaproteobacteria,1X5SX@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
LZS3_k127_273138_1	640081.Dsui_2150	1.801e-81	287.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,2KU66@206389|Rhodocyclales	206389|Rhodocyclales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_273138_4	765912.Thimo_1591	1.117e-24	108.0	COG0266@1|root,COG0266@2|Bacteria,1N1J5@1224|Proteobacteria,1RNS9@1236|Gammaproteobacteria,1WYFP@135613|Chromatiales	135613|Chromatiales	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	4.2.99.18	ko:K05522	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
LZS3_k127_274159_1	523841.HFX_1253	7.424e-23	100.0	COG0633@1|root,arCOG02987@2157|Archaea,2XYZQ@28890|Euryarchaeota,23WV2@183963|Halobacteria	183963|Halobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
LZS3_k127_274159_0	1333856.L686_01265	8.16e-160	514.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1Z0CB@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	U	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS3_k127_2776609_1	713586.KB900536_gene2820	6.164e-101	341.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS3_k127_2776609_0	768671.ThimaDRAFT_3432	9.52e-109	364.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS3_k127_2792097_0	749414.SBI_03482	3.235e-104	349.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_2792097_1	404589.Anae109_2933	7.005e-46	172.0	2CK59@1|root,32RQ2@2|Bacteria,1NX6Z@1224|Proteobacteria,430FH@68525|delta/epsilon subdivisions,2WVZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2792097_2	1205680.CAKO01000026_gene4554	3.324e-31	127.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2U9NV@28211|Alphaproteobacteria,2JTV5@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
LZS3_k127_2792097_3	1120936.KB907212_gene5113	2.494e-28	124.0	COG0346@1|root,COG0346@2|Bacteria,2IFUM@201174|Actinobacteria,4EJD3@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_279322_3	247156.NFA_15720	3.299e-34	136.0	COG2021@1|root,COG2021@2|Bacteria,2H373@201174|Actinobacteria,4G9AT@85025|Nocardiaceae	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_279322_1	1123368.AUIS01000023_gene925	2.706e-102	349.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS3_k127_279322_0	644282.Deba_1492	9.713e-154	499.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,42NUM@68525|delta/epsilon subdivisions,2WKR2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 2-nitropropane dioxygenase NPD	-	-	-	-	-	-	-	-	-	-	-	-	NMO
LZS3_k127_279322_5	1292020.H483_0105925	1.44e-30	126.0	2DJ5J@1|root,32UCF@2|Bacteria,2II98@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_279322_2	1122604.JONR01000025_gene4607	5.62e-60	212.0	COG3791@1|root,COG3791@2|Bacteria,1N3P3@1224|Proteobacteria,1S57G@1236|Gammaproteobacteria,1X8YJ@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
LZS3_k127_279322_4	861299.J421_2420	7.061e-34	144.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_2796838_1	1123320.KB889585_gene1873	4.469e-44	164.0	COG1960@1|root,COG1960@2|Bacteria,2GK9C@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE27	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_2796838_0	1121374.KB891575_gene1051	3.694e-105	349.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,1RRVQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
LZS3_k127_2796838_2	1219035.NT2_05_04590	1.351e-24	116.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,1QV6D@1224|Proteobacteria,2TTB1@28211|Alphaproteobacteria,2K8G7@204457|Sphingomonadales	204457|Sphingomonadales	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_28219_2	349521.HCH_01986	9.532e-31	131.0	COG0393@1|root,COG0393@2|Bacteria,1N6BK@1224|Proteobacteria,1SAFJ@1236|Gammaproteobacteria,1XMNR@135619|Oceanospirillales	135619|Oceanospirillales	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS3_k127_28219_1	118161.KB235922_gene644	3.415e-44	163.0	COG0393@1|root,COG0393@2|Bacteria,1G7AD@1117|Cyanobacteria,3VK2F@52604|Pleurocapsales	1117|Cyanobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS3_k127_28219_0	1122611.KB903956_gene211	3.004e-66	233.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4EHBH@85012|Streptosporangiales	201174|Actinobacteria	S	Reductase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Reductase_C
LZS3_k127_2828988_1	1197130.BAFM01000002_gene584	2.271e-48	201.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
LZS3_k127_2828988_0	861299.J421_3119	6.123e-80	304.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_2828988_2	379066.GAU_1245	1.587e-47	195.0	COG0392@1|root,COG0392@2|Bacteria,1ZT5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS3_k127_2828988_3	1121406.JAEX01000016_gene1883	8.513e-22	103.0	COG2227@1|root,COG2227@2|Bacteria,1RKH0@1224|Proteobacteria,42Q2I@68525|delta/epsilon subdivisions,2WJME@28221|Deltaproteobacteria,2M9G0@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
LZS3_k127_2832850_2	1229780.BN381_70071	8.995e-27	124.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,Polysacc_synt_3,Polysacc_synt_C
LZS3_k127_2832850_1	391735.Veis_4953	2.171e-116	386.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,Polysacc_synt_3,Polysacc_synt_C
LZS3_k127_2832850_3	344747.PM8797T_07122	5.189e-21	108.0	COG2365@1|root,COG2365@2|Bacteria,2J0XH@203682|Planctomycetes	203682|Planctomycetes	T	Protein tyrosine serine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc,Y_phosphatase3
LZS3_k127_2832850_0	1245469.S58_47850	1.853e-245	771.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TRNK@28211|Alphaproteobacteria,3JVXA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS3_k127_2833894_0	257310.BB1447	6.563e-293	917.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,3T1KP@506|Alcaligenaceae	28216|Betaproteobacteria	F	Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
LZS3_k127_2833894_3	1125863.JAFN01000001_gene353	4.848e-141	473.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
LZS3_k127_2833894_5	1125863.JAFN01000001_gene352	2.008e-131	443.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
LZS3_k127_2833894_4	338963.Pcar_1614	8.184e-140	464.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,43TVY@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS3_k127_2833894_6	1232410.KI421413_gene593	2.013e-112	370.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS3_k127_2833894_7	1121468.AUBR01000026_gene2950	2.867e-57	206.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,42G0W@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
LZS3_k127_2833894_9	338963.Pcar_1617	1.284e-37	164.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,43SF5@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
LZS3_k127_2833894_1	1123354.AUDR01000020_gene1996	2.147e-233	752.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,1KRFE@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
LZS3_k127_2833894_2	518766.Rmar_1858	8.894e-142	457.0	COG0451@1|root,COG0451@2|Bacteria,4NEZX@976|Bacteroidetes,1FIS7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS3_k127_2833894_8	42256.RradSPS_0235	5.023e-53	196.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,4CPVG@84995|Rubrobacteria	84995|Rubrobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS3_k127_283679_1	404380.Gbem_3350	8.859e-73	271.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
LZS3_k127_283679_0	1121468.AUBR01000014_gene2228	1.005e-167	547.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,42EWK@68295|Thermoanaerobacterales	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_283679_2	748247.AZKH_3109	7.355e-35	145.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,2KU7Q@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
LZS3_k127_283679_3	479434.Sthe_1875	5.362e-26	110.0	COG0134@1|root,COG0134@2|Bacteria,2G6GG@200795|Chloroflexi,27XGP@189775|Thermomicrobia	189775|Thermomicrobia	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
LZS3_k127_2858823_0	1146883.BLASA_1297	6.677e-51	190.0	COG1131@1|root,COG1131@2|Bacteria,2IH0X@201174|Actinobacteria	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_2865840_0	396595.TK90_2515	8.954e-161	529.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS3_k127_2865840_1	83406.HDN1F_05510	1.33e-56	209.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,1RXG4@1236|Gammaproteobacteria,1J9BT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2869894_1	483219.LILAB_28305	2.628e-96	344.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2YUC9@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_2869894_0	1125863.JAFN01000001_gene760	1.268e-103	350.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
LZS3_k127_288135_0	339670.Bamb_5588	1.448e-31	136.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VPRV@28216|Betaproteobacteria,1K3CH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS3_k127_288135_1	118173.KB235914_gene3372	6.243e-08	61.0	COG1834@1|root,COG1915@1|root,COG1834@2|Bacteria,COG1915@2|Bacteria,1G2AU@1117|Cyanobacteria,1H7S0@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf,Saccharop_dh_N
LZS3_k127_2891202_2	1173026.Glo7428_0590	1.024e-74	260.0	COG1216@1|root,COG1216@2|Bacteria,1FZX3@1117|Cyanobacteria	1117|Cyanobacteria	KT	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_2891202_1	869210.Marky_0500	8.345e-89	329.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_2891202_0	871585.BDGL_003043	6.083e-118	416.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,3NM9J@468|Moraxellaceae	1236|Gammaproteobacteria	GM	Outer membrane lipoprotein-sorting protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	LolA_like,MMPL,Polyketide_cyc2
LZS3_k127_2892328_1	402881.Plav_1539	4.61e-94	318.0	COG0346@1|root,COG0346@2|Bacteria,1PNKN@1224|Proteobacteria,2V9TG@28211|Alphaproteobacteria,1JQJD@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_2892328_0	402881.Plav_0131	2.846e-114	387.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TRHJ@28211|Alphaproteobacteria,1JQ3J@119043|Rhodobiaceae	28211|Alphaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS3_k127_2903652_0	1388763.O165_021170	2.422e-111	373.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,1RMPP@1236|Gammaproteobacteria,1YV38@136845|Pseudomonas putida group	1236|Gammaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF2	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_2904288_1	57918.XP_004290012.1	1.548e-05	57.0	KOG0406@1|root,KOG0406@2759|Eukaryota,37SHI@33090|Viridiplantae,3GH2W@35493|Streptophyta,4JT9S@91835|fabids	35493|Streptophyta	O	Glutathione transferase GST 23-like	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N
LZS3_k127_2904288_0	1122612.AUBA01000002_gene1747	9.669e-110	362.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria,2KE98@204457|Sphingomonadales	204457|Sphingomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_2911619_2	1121918.ARWE01000001_gene180	6.705e-27	113.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,42V21@68525|delta/epsilon subdivisions,2WRFF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
LZS3_k127_2911619_1	756272.Plabr_3437	7.118e-37	146.0	COG2010@1|root,COG2010@2|Bacteria,2J3TA@203682|Planctomycetes	203682|Planctomycetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
LZS3_k127_2911619_3	237368.SCABRO_02550	8.603e-15	80.0	COG2303@1|root,COG3485@1|root,COG2303@2|Bacteria,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	choD_1	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	CarboxypepD_reg,FAD_oxidored,GMC_oxred_C,GMC_oxred_N,PhoD
LZS3_k127_2911619_0	448385.sce0567	2.59e-40	159.0	COG3973@1|root,COG3973@2|Bacteria,1P638@1224|Proteobacteria,42MXR@68525|delta/epsilon subdivisions,2WK1Z@28221|Deltaproteobacteria,2Z32G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD_C_2
LZS3_k127_2918740_0	1121019.AUMN01000012_gene2314	3.853e-169	558.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
LZS3_k127_2918740_5	1462527.CCDM010000001_gene2522	8.167e-127	451.0	COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,4HBKB@91061|Bacilli	91061|Bacilli	EQ	COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit	-	-	3.5.2.14,6.4.1.6	ko:K01474,ko:K10854	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
LZS3_k127_2918740_9	1121019.AUMN01000012_gene2312	1.128e-51	192.0	COG4647@1|root,COG4647@2|Bacteria,2GRZS@201174|Actinobacteria	201174|Actinobacteria	Q	acetone carboxylase	-	-	6.4.1.6	ko:K10856	-	-	-	-	ko00000,ko01000	-	-	-	Acetone_carb_G
LZS3_k127_2918740_4	1348657.M622_02815	1.368e-130	437.0	COG1804@1|root,COG1804@2|Bacteria	2|Bacteria	C	formyl-CoA transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_2918740_1	1348657.M622_02810	1.624e-148	502.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KXPJ@206389|Rhodocyclales	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_2918740_3	1348657.M622_02765	2.779e-144	490.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KXPJ@206389|Rhodocyclales	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_2918740_2	1348657.M622_02805	5.551e-148	473.0	COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,2VJ36@28216|Betaproteobacteria,2KW1N@206389|Rhodocyclales	28216|Betaproteobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_2918740_7	309801.trd_A0777	2.538e-81	294.0	COG1319@1|root,COG1319@2|Bacteria,2G7KW@200795|Chloroflexi,27Z00@189775|Thermomicrobia	189775|Thermomicrobia	C	CO dehydrogenase flavoprotein domain protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS3_k127_2918740_8	1382306.JNIM01000001_gene2084	1.196e-60	221.0	COG2080@1|root,COG2080@2|Bacteria,2G8E9@200795|Chloroflexi	200795|Chloroflexi	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
LZS3_k127_2918740_6	1348657.M622_02760	2.661e-92	318.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS3_k127_2933768_1	358823.DF19_30565	1.015e-15	81.0	2BXSN@1|root,32R1X@2|Bacteria,2GN1N@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4243
LZS3_k127_2933768_0	378806.STAUR_2989	2.924e-117	392.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2YU80@29|Myxococcales	28221|Deltaproteobacteria	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
LZS3_k127_2954945_0	1313172.YM304_06620	3.817e-56	208.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS3_k127_2954945_1	479434.Sthe_1357	5.112e-42	168.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,27YSI@189775|Thermomicrobia	189775|Thermomicrobia	E	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
LZS3_k127_2955713_0	644282.Deba_2373	3.076e-165	538.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS3_k127_2960344_0	215803.DB30_7958	8.203e-56	215.0	COG3391@1|root,COG3391@2|Bacteria,1P80Y@1224|Proteobacteria,43959@68525|delta/epsilon subdivisions,2X4BM@28221|Deltaproteobacteria,2YYPB@29|Myxococcales	1224|Proteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2960483_0	335543.Sfum_3063	5.659e-118	394.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2MQ40@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PDZ domain (Also known as DHR or GLGF)	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS3_k127_2960483_1	1242864.D187_006567	1.714e-32	130.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2YVR8@29|Myxococcales	28221|Deltaproteobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
LZS3_k127_2961466_0	1382306.JNIM01000001_gene999	8.373e-64	236.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
LZS3_k127_2961466_1	1229780.BN381_10319	2.462e-34	144.0	COG2050@1|root,COG2050@2|Bacteria,2I11Y@201174|Actinobacteria,3UXR4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS3_k127_2973127_0	556267.HWAG_00749	6.318e-24	118.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2YM7Z@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Fibronectin type 3 domain-containing protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
LZS3_k127_2973127_1	1246626.BleG1_3070	7.272e-06	54.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Glucosaminidase,SH3_3
LZS3_k127_2974560_0	469383.Cwoe_3478	8.359e-109	370.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_2974560_1	1123504.JQKD01000006_gene1649	3.047e-60	224.0	COG0500@1|root,COG2226@2|Bacteria,1MVXG@1224|Proteobacteria,2VM9F@28216|Betaproteobacteria,4ADEU@80864|Comamonadaceae	28216|Betaproteobacteria	H	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
LZS3_k127_2977842_2	430998.XP_007672735.1	2.982e-60	218.0	COG0491@1|root,KOG0813@2759|Eukaryota,38BZ4@33154|Opisthokonta,3P10J@4751|Fungi,3QKGV@4890|Ascomycota,1ZXW2@147541|Dothideomycetes,3MGE5@451867|Dothideomycetidae	4751|Fungi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_2977842_1	330214.NIDE1515	6.892e-110	385.0	COG0312@1|root,COG0312@2|Bacteria,3J0P7@40117|Nitrospirae	40117|Nitrospirae	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS3_k127_2977842_0	765912.Thimo_2604	1.741e-166	530.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales	135613|Chromatiales	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS3_k127_298550_1	395495.Lcho_1398	6.471e-72	251.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KN02@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_298550_0	1307759.JOMJ01000004_gene2863	2.514e-129	419.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2M80I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS3_k127_298550_2	448385.sce0856	3.251e-18	94.0	COG0484@1|root,COG2206@1|root,COG0484@2|Bacteria,COG2206@2|Bacteria,1QX6J@1224|Proteobacteria,43BZ5@68525|delta/epsilon subdivisions,2X79W@28221|Deltaproteobacteria,2Z3EH@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
LZS3_k127_2989031_3	234267.Acid_7037	3.787e-18	93.0	COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria	57723|Acidobacteria	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
LZS3_k127_2989031_0	713586.KB900536_gene2819	1.018e-123	411.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS3_k127_2989031_1	713586.KB900536_gene2820	2.078e-93	335.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS3_k127_2989031_2	404589.Anae109_1962	4.212e-80	271.0	COG0500@1|root,COG2226@2|Bacteria,1NV2S@1224|Proteobacteria,43AKS@68525|delta/epsilon subdivisions,2X60S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_2989031_4	314278.NB231_13081	6.154e-18	89.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1WY36@135613|Chromatiales	135613|Chromatiales	E	PFAM lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
LZS3_k127_3002947_2	234621.RER_58640	2.22e-19	92.0	COG0596@1|root,COG0596@2|Bacteria,2I9EM@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
LZS3_k127_3002947_0	502025.Hoch_5960	1.741e-62	226.0	COG1752@1|root,COG1752@2|Bacteria,1PEH4@1224|Proteobacteria,42XKH@68525|delta/epsilon subdivisions,2WTA6@28221|Deltaproteobacteria,2YUHG@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS3_k127_3005119_1	338969.Rfer_0691	4.859e-79	294.0	COG2244@1|root,COG2244@2|Bacteria,1MUMD@1224|Proteobacteria,2WEWR@28216|Betaproteobacteria,4AJNX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
LZS3_k127_3005119_0	1156937.MFUM_730010	1.24e-95	332.0	COG1611@1|root,COG1611@2|Bacteria,46SEG@74201|Verrucomicrobia,37G67@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
LZS3_k127_3005119_3	648996.Theam_1352	8.441e-17	89.0	COG4968@1|root,COG4968@2|Bacteria,2G5IB@200783|Aquificae	200783|Aquificae	NU	Pfam:N_methyl_2	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
LZS3_k127_3005119_2	479431.Namu_4273	4.341e-21	95.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EU7W@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_3025657_0	391625.PPSIR1_15000	2.97e-115	379.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2WQU9@28221|Deltaproteobacteria,2YXHW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
LZS3_k127_3025657_1	1121920.AUAU01000004_gene849	2.136e-113	375.0	COG0861@1|root,COG0861@2|Bacteria,3Y37C@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
LZS3_k127_3029013_2	1123322.KB904701_gene320	1.153e-23	115.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
LZS3_k127_3029013_3	1122239.AULS01000012_gene1075	5.986e-13	81.0	COG1051@1|root,COG2062@1|root,COG1051@2|Bacteria,COG2062@2|Bacteria,2I2N2@201174|Actinobacteria,4FMSI@85023|Microbacteriaceae	201174|Actinobacteria	FT	Phosphoglycerate mutase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
LZS3_k127_3029013_0	477641.MODMU_4459	6.744e-225	716.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,4ERTG@85013|Frankiales	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
LZS3_k127_3029013_1	1121033.AUCF01000005_gene5372	5.966e-30	124.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2TQRV@28211|Alphaproteobacteria,2JQ4S@204441|Rhodospirillales	204441|Rhodospirillales	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
LZS3_k127_3033607_3	448385.sce0906	5.002e-29	122.0	COG0122@1|root,COG0350@1|root,COG0122@2|Bacteria,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,43ARM@68525|delta/epsilon subdivisions,2X65K@28221|Deltaproteobacteria,2Z392@29|Myxococcales	28221|Deltaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,HhH-GPD
LZS3_k127_3033607_0	685727.REQ_06870	1.581e-83	302.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4FZKA@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_3033607_1	479434.Sthe_3020	3.327e-48	180.0	COG1670@1|root,COG1670@2|Bacteria,2G6UG@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
LZS3_k127_3033607_2	1150599.MPHLEI_07459	5.88e-30	128.0	2EJXJ@1|root,33DN7@2|Bacteria,2I988@201174|Actinobacteria,237DZ@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
LZS3_k127_3049669_2	439235.Dalk_1847	1.642e-122	405.0	COG1960@1|root,COG1960@2|Bacteria,1P7WH@1224|Proteobacteria,42QKR@68525|delta/epsilon subdivisions,2WM93@28221|Deltaproteobacteria,2MJM8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3049669_4	1348657.M622_04425	7.119e-85	289.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS3_k127_3049669_1	1245471.PCA10_29470	3.603e-154	510.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,1S0KG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_3049669_0	1348657.M622_04415	1.619e-193	619.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2VR64@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_3049669_3	83406.HDN1F_20090	2.811e-102	366.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,1T2GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1,1.8.5.3	ko:K00370,ko:K07306,ko:K17050	ko00910,ko00920,ko01120,ko02020,map00910,map00920,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497,R09501	RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
LZS3_k127_3058180_0	1313172.YM304_00950	1.553e-216	686.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_3059186_0	234267.Acid_6183	9.263e-41	171.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_3063359_0	1254432.SCE1572_46990	1.054e-96	321.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
LZS3_k127_3063359_2	395493.BegalDRAFT_1938	3.313e-36	150.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
LZS3_k127_3063359_1	1123400.KB904747_gene576	5.626e-45	166.0	2B3E9@1|root,31W34@2|Bacteria,1MZ95@1224|Proteobacteria,1SA6A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3063359_4	1144307.PMI04_02913	3.598e-12	76.0	COG2146@1|root,COG2146@2|Bacteria,1N4ER@1224|Proteobacteria,2UEP2@28211|Alphaproteobacteria,2K6B0@204457|Sphingomonadales	204457|Sphingomonadales	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
LZS3_k127_3063359_3	247634.GPB2148_2062	3.073e-21	105.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria,1SG78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3064176_5	688269.Theth_1407	2.278e-05	48.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
LZS3_k127_3064176_3	1168059.KB899087_gene3133	3.795e-07	54.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS3_k127_3064176_0	1122604.JONR01000034_gene418	1.005e-39	162.0	295V1@1|root,2ZT62@2|Bacteria,1P75A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3064176_2	867845.KI911784_gene2170	8.366e-08	57.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07061	-	-	-	-	ko00000,ko02048	-	-	-	NTP_transf_2
LZS3_k127_3064176_1	1125863.JAFN01000001_gene2136	2.53e-21	102.0	COG2250@1|root,COG2250@2|Bacteria,1P4MX@1224|Proteobacteria	1224|Proteobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
LZS3_k127_3068735_1	391008.Smal_3909	8.371e-74	252.0	COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,1RMCB@1236|Gammaproteobacteria,1X4MA@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_3068735_0	1254432.SCE1572_37245	6.322e-126	420.0	COG0644@1|root,COG0644@2|Bacteria,1MZ3Z@1224|Proteobacteria,433ZE@68525|delta/epsilon subdivisions,2X47M@28221|Deltaproteobacteria,2Z01K@29|Myxococcales	28221|Deltaproteobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Trp_halogenase
LZS3_k127_3098221_0	1192034.CAP_8276	4.177e-112	394.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,1R0E4@1224|Proteobacteria,43EEC@68525|delta/epsilon subdivisions,2X84M@28221|Deltaproteobacteria,2YUU3@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
LZS3_k127_3098221_1	864051.BurJ1DRAFT_4983	1.33e-29	134.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,SGL
LZS3_k127_3111085_2	935565.JAEM01000010_gene1930	3.179e-53	192.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TSKH@28211|Alphaproteobacteria,2PXB7@265|Paracoccus	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_3111085_0	1292034.OR37_01982	3.762e-109	366.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria,2KHX3@204458|Caulobacterales	204458|Caulobacterales	C	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3111085_1	710421.Mycch_0546	5.08e-93	316.0	COG0451@1|root,COG0451@2|Bacteria,2HS3E@201174|Actinobacteria,23D32@1762|Mycobacteriaceae	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,F420H2_quin_red
LZS3_k127_311661_0	448385.sce7772	1.024e-107	374.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,439SK@68525|delta/epsilon subdivisions,2X55M@28221|Deltaproteobacteria,2Z05C@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_311661_2	290397.Adeh_0402	5.288e-79	299.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42S2Z@68525|delta/epsilon subdivisions,2X5JB@28221|Deltaproteobacteria,2Z35Y@29|Myxococcales	28221|Deltaproteobacteria	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
LZS3_k127_311661_3	1163409.UUA_12545	3.717e-65	239.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,1T04E@1236|Gammaproteobacteria,1XCYS@135614|Xanthomonadales	135614|Xanthomonadales	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
LZS3_k127_311661_1	469383.Cwoe_1310	9.007e-107	358.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4CSBE@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_3116815_0	1121033.AUCF01000036_gene3969	2.781e-82	282.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,2JSE3@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_3117492_0	1283299.AUKG01000002_gene4966	6.039e-116	391.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_3121372_7	402626.Rpic_4367	2.861e-18	100.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,1KBW0@119060|Burkholderiaceae	28216|Betaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
LZS3_k127_3121372_0	1173024.KI912148_gene3732	1.761e-283	897.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_3121372_2	395495.Lcho_4268	2.115e-101	340.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJ7G@28216|Betaproteobacteria,1KJCW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_3121372_1	1262914.BN533_02200	5.746e-190	608.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4H1XW@909932|Negativicutes	909932|Negativicutes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
LZS3_k127_3121372_5	290397.Adeh_0078	1.517e-39	155.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3121372_6	404589.Anae109_3186	6.137e-34	152.0	COG3040@1|root,COG3040@2|Bacteria,1RIHP@1224|Proteobacteria,42SSW@68525|delta/epsilon subdivisions,2X6M9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
LZS3_k127_3121372_3	1123261.AXDW01000013_gene3499	1.339e-58	215.0	COG0491@1|root,COG0491@2|Bacteria,1N3G4@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_3121372_4	1385519.N801_11735	1.391e-54	210.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4FFET@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_3121372_8	319225.Plut_1457	0.00025	45.0	COG0068@1|root,COG0068@2|Bacteria,1FDST@1090|Chlorobi	1090|Chlorobi	O	Belongs to the carbamoyltransferase HypF family	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
LZS3_k127_312614_1	472759.Nhal_0313	8.64e-133	452.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1RNID@1236|Gammaproteobacteria,1WX07@135613|Chromatiales	135613|Chromatiales	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS3_k127_312614_2	1458275.AZ34_07525	1.383e-83	284.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,4AARP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
LZS3_k127_312614_0	1458275.AZ34_07530	2.29e-148	480.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,4AAI7@80864|Comamonadaceae	28216|Betaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase
LZS3_k127_3126363_2	1476583.DEIPH_ctg040orf0071	1.369e-36	142.0	COG2329@1|root,COG2329@2|Bacteria,1WN1E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Antibiotic biosynthesis monooxygenase	yczJ	-	-	-	-	-	-	-	-	-	-	-	ABM
LZS3_k127_3126363_0	63737.Npun_R1245	4.746e-52	190.0	2D8VC@1|root,32TS1@2|Bacteria,1G8H1@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3126363_3	1238450.VIBNISOn1_1900022	1.071e-06	60.0	2A0YP@1|root,30P3X@2|Bacteria,1NDHJ@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
LZS3_k127_3126363_1	1254432.SCE1572_06490	6.496e-44	161.0	COG0122@1|root,COG0350@1|root,COG0122@2|Bacteria,COG0350@2|Bacteria,1MVF7@1224|Proteobacteria,43ARM@68525|delta/epsilon subdivisions,2X65K@28221|Deltaproteobacteria,2Z392@29|Myxococcales	28221|Deltaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,HhH-GPD
LZS3_k127_3136593_1	671143.DAMO_0884	2.734e-56	207.0	COG2887@1|root,COG2887@2|Bacteria,2NQTZ@2323|unclassified Bacteria	2|Bacteria	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1
LZS3_k127_3136593_0	1123072.AUDH01000010_gene3443	1.793e-69	243.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
LZS3_k127_3136593_3	644282.Deba_1384	2.771e-16	86.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
LZS3_k127_3136593_2	767817.Desgi_4196	6.071e-20	96.0	COG3339@1|root,COG3339@2|Bacteria,1V7PK@1239|Firmicutes,2493Y@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
LZS3_k127_3140161_0	1449976.KALB_3405	1.051e-189	607.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,4E0V7@85010|Pseudonocardiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_3140161_1	519989.ECTPHS_04493	1.022e-178	578.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1WX2K@135613|Chromatiales	135613|Chromatiales	P	sulphate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
LZS3_k127_3149973_1	56780.SYN_00535	2.224e-61	217.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2WKG9@28221|Deltaproteobacteria,2MS0Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
LZS3_k127_3149973_3	1401064.HMPREF2129_04610	7.7e-05	55.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,22M4R@1653|Corynebacteriaceae	201174|Actinobacteria	T	FHA domain	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
LZS3_k127_3149973_2	644282.Deba_1036	1.002e-47	184.0	COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,43B3M@68525|delta/epsilon subdivisions,2X6HF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_3149973_0	1280954.HPO_07687	2.145e-104	358.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,43W8Z@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4994,Sulfatase
LZS3_k127_3154528_2	1267535.KB906767_gene5001	2.865e-53	207.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
LZS3_k127_3154528_0	671143.DAMO_0812	7.636e-204	657.0	COG0210@1|root,COG0210@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS3_k127_3154528_1	452637.Oter_1765	6.487e-106	364.0	COG1215@1|root,COG1215@2|Bacteria,46SRA@74201|Verrucomicrobia,3K7C7@414999|Opitutae	414999|Opitutae	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_3154528_5	1001585.MDS_0728	2.919e-49	196.0	COG2227@1|root,COG2227@2|Bacteria,1N6SE@1224|Proteobacteria,1SCC1@1236|Gammaproteobacteria,1YEEZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
LZS3_k127_3154528_3	290397.Adeh_3051	8.658e-52	201.0	COG1216@1|root,COG1216@2|Bacteria,1QW1K@1224|Proteobacteria,43BRI@68525|delta/epsilon subdivisions,2WN0V@28221|Deltaproteobacteria,2Z30Y@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_3154528_6	443143.GM18_0979	9.212e-05	50.0	COG2456@1|root,COG2456@2|Bacteria,1NF5Z@1224|Proteobacteria,42VNI@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
LZS3_k127_3154528_4	760568.Desku_3526	3.632e-50	196.0	COG3119@1|root,COG3119@2|Bacteria,1VAJC@1239|Firmicutes,24C1C@186801|Clostridia	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_3165518_0	2074.JNYD01000001_gene5846	2.598e-71	265.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2H57H@201174|Actinobacteria,4EF5W@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
LZS3_k127_3177357_1	1177181.T9A_00389	4.977e-48	183.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,1RPBQ@1236|Gammaproteobacteria,1XPNY@135619|Oceanospirillales	135619|Oceanospirillales	E	COG2303 Choline dehydrogenase and related flavoproteins	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
LZS3_k127_3177357_0	1282876.BAOK01000002_gene507	5.078e-99	342.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria	1224|Proteobacteria	V	Mate efflux family protein	yeeO	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
LZS3_k127_3177357_2	1121468.AUBR01000026_gene2916	1.845e-20	102.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,24I2P@186801|Clostridia,42GMX@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	acuB	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
LZS3_k127_3177357_3	1201290.M902_3135	7.521e-05	51.0	2CIY5@1|root,2ZET1@2|Bacteria,1P8MM@1224|Proteobacteria,4330I@68525|delta/epsilon subdivisions,2MUET@213481|Bdellovibrionales,2WXKY@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3177396_0	237368.SCABRO_03967	4.947e-109	372.0	COG1132@1|root,COG1132@2|Bacteria,2IXKY@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS3_k127_317882_3	118173.KB235914_gene3485	0.0005385	54.0	COG2833@1|root,COG2833@2|Bacteria,1GQKS@1117|Cyanobacteria,1HI36@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
LZS3_k127_317882_2	1458357.BG58_09135	2.427e-35	139.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2WEPY@28216|Betaproteobacteria,1KH72@119060|Burkholderiaceae	28216|Betaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
LZS3_k127_317882_0	1183438.GKIL_3129	4.418e-287	895.0	COG0365@1|root,COG0365@2|Bacteria,1G0E7@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS3_k127_317882_1	1122951.ATUE01000005_gene1809	2.356e-90	303.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,3NJMZ@468|Moraxellaceae	1236|Gammaproteobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
LZS3_k127_3215128_0	1121035.AUCH01000005_gene101	8.251e-29	126.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,2KVW3@206389|Rhodocyclales	206389|Rhodocyclales	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
LZS3_k127_3218409_7	1042877.GQS_07260	4.772e-06	59.0	COG0392@1|root,arCOG00899@2157|Archaea,2XTI1@28890|Euryarchaeota,243F4@183968|Thermococci	183968|Thermococci	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS3_k127_3218409_0	1157943.KB892705_gene3119	3.262e-188	612.0	COG0370@1|root,COG0370@2|Bacteria,2GTV2@201174|Actinobacteria,235FD@1762|Mycobacteriaceae	201174|Actinobacteria	P	Ferrous iron transport protein B C terminus	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
LZS3_k127_3218409_6	521393.JH806632_gene761	1.733e-14	76.0	COG1918@1|root,COG1918@2|Bacteria,2GX6H@201174|Actinobacteria,4D611@85005|Actinomycetales	201174|Actinobacteria	P	FeoA domain protein	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
LZS3_k127_3218409_3	1242864.D187_000160	3.564e-96	336.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,2YTWZ@29|Myxococcales	28221|Deltaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
LZS3_k127_3218409_5	1131269.AQVV01000018_gene1933	5.141e-35	146.0	COG0838@1|root,COG0838@2|Bacteria	2|Bacteria	C	NADH dehydrogenase (ubiquinone) activity	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
LZS3_k127_3218409_4	1238182.C882_4188	2.7e-36	149.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,2JRYM@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1905 NADH ubiquinone oxidoreductase 24 kD subunit	nuoE	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
LZS3_k127_3218409_1	671143.DAMO_2696	3.072e-153	495.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
LZS3_k127_3218409_2	945713.IALB_0893	2.096e-97	326.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
LZS3_k127_3223336_1	797304.Natgr_0948	6.322e-27	113.0	COG0169@1|root,arCOG01033@2157|Archaea,2XV7K@28890|Euryarchaeota,23SSE@183963|Halobacteria	183963|Halobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
LZS3_k127_3223336_2	1159870.KB907784_gene2251	3.454e-22	98.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,3T4TJ@506|Alcaligenaceae	28216|Betaproteobacteria	J	there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
LZS3_k127_3223336_3	469383.Cwoe_1351	2.628e-18	90.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4CQNC@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
LZS3_k127_3223336_0	243233.MCA3015	3.012e-151	489.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,1RPE8@1236|Gammaproteobacteria,1XDW4@135618|Methylococcales	135618|Methylococcales	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_3223594_2	1242864.D187_003435	1.857e-105	350.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2WNI2@28221|Deltaproteobacteria,2YU7J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C,Haem_bd,Pkinase
LZS3_k127_3223594_4	96561.Dole_1053	2.115e-61	228.0	COG2128@1|root,COG2128@2|Bacteria,1PSNE@1224|Proteobacteria,42XCT@68525|delta/epsilon subdivisions,2WSJD@28221|Deltaproteobacteria,2MP2A@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS3_k127_3223594_3	378806.STAUR_1936	1.545e-82	280.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2WMP7@28221|Deltaproteobacteria,2YUHQ@29|Myxococcales	28221|Deltaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
LZS3_k127_3223594_1	509190.Cseg_1260	6.171e-123	423.0	COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,2TT9T@28211|Alphaproteobacteria,2KG3G@204458|Caulobacterales	204458|Caulobacterales	I	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_3223594_0	1282876.BAOK01000001_gene2536	2.901e-147	478.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,4BT82@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3226368_0	522306.CAP2UW1_3413	2.597e-125	408.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,2VJGG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_5
LZS3_k127_3226368_1	1163617.SCD_n00356	3.229e-97	325.0	COG1131@1|root,COG1131@2|Bacteria,1MXHE@1224|Proteobacteria,2VN8A@28216|Betaproteobacteria	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_3237252_0	866536.Belba_0418	8.524e-154	501.0	COG0119@1|root,COG0119@2|Bacteria,4NF3N@976|Bacteroidetes,47JWF@768503|Cytophagia	976|Bacteroidetes	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA_1	-	2.3.1.182	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	M00535	R07399	RC00004,RC01205	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
LZS3_k127_3239480_0	187272.Mlg_2359	5.182e-185	592.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,1S7F7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit	-	-	-	ko:K15060	ko00627,ko01120,map00627,map01120	-	R09275	RC00392,RC01533	ko00000,ko00001	-	-	-	Rieske
LZS3_k127_3239480_1	713586.KB900536_gene1948	2.585e-37	143.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RVXM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
LZS3_k127_3245598_0	398767.Glov_1013	2.129e-124	403.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_3245598_1	272134.KB731326_gene304	4.268e-57	205.0	COG0500@1|root,COG2226@2|Bacteria,1GCN5@1117|Cyanobacteria	1117|Cyanobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS3_k127_3245598_2	2903.EOD28111	7.458e-28	127.0	COG2057@1|root,KOG3822@2759|Eukaryota	2759|Eukaryota	I	3-oxoacid CoA-transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
LZS3_k127_3245652_1	644282.Deba_1905	9.488e-106	371.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
LZS3_k127_3245652_0	1192034.CAP_6585	1.676e-118	387.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42MTW@68525|delta/epsilon subdivisions,2WJ0J@28221|Deltaproteobacteria,2YUI8@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
LZS3_k127_3246352_2	1278078.G419_22534	1.687e-90	318.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4G5JR@85025|Nocardiaceae	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_3246352_4	1458357.BG58_25605	1.974e-31	141.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2W1GH@28216|Betaproteobacteria,1K71F@119060|Burkholderiaceae	28216|Betaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
LZS3_k127_3246352_1	1121468.AUBR01000035_gene1382	2.972e-110	383.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42HW8@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_3246352_0	96561.Dole_0194	5.67e-234	756.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,43BQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	ddhA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3	ko:K00370,ko:K07306,ko:K10700,ko:K16964,ko:K17050	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500,R09501	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8,5.A.3.9	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
LZS3_k127_3246352_3	378806.STAUR_4406	1.215e-40	169.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WMD0@28221|Deltaproteobacteria,2YZDI@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS3_k127_3247355_2	1121439.dsat_0613	1.602e-06	60.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42PKZ@68525|delta/epsilon subdivisions,2WIQZ@28221|Deltaproteobacteria,2MACK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
LZS3_k127_3247355_0	1121406.JAEX01000002_gene1118	1.451e-117	392.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2M8VR@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
LZS3_k127_3247355_1	709797.CSIRO_3104	1.807e-07	55.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2TU0F@28211|Alphaproteobacteria,3JQNI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS3_k127_3267400_5	1123274.KB899416_gene2555	2.109e-13	83.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HAMP,HATPase_c,HisKA,PAS,dCache_3
LZS3_k127_3267400_2	1123274.KB899416_gene2554	1.68e-64	228.0	COG0745@1|root,COG0745@2|Bacteria	1123274.KB899416_gene2554|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3267400_0	485913.Krac_11289	1.199e-88	299.0	COG3363@1|root,COG3363@2|Bacteria	2|Bacteria	F	IMP cyclohydrolase activity	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	IMP_cyclohyd
LZS3_k127_3267400_3	267377.MMP1550	1.583e-41	171.0	COG2085@1|root,arCOG00457@2157|Archaea,2XUD2@28890|Euryarchaeota,23QAN@183939|Methanococci	183939|Methanococci	C	PFAM NADP oxidoreductase coenzyme F420-dependent	-	GO:0000041,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006826,GO:0008150,GO:0008152,GO:0008823,GO:0015677,GO:0015682,GO:0016020,GO:0016021,GO:0016491,GO:0016722,GO:0016723,GO:0030001,GO:0031224,GO:0031226,GO:0033216,GO:0034220,GO:0034755,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0052851,GO:0055085,GO:0055114,GO:0071944,GO:0072512,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098706,GO:0098711,GO:0098739,GO:0099587	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
LZS3_k127_3267400_4	1131269.AQVV01000011_gene2520	9.599e-28	117.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
LZS3_k127_3267400_1	570952.ATVH01000013_gene3000	8.405e-71	246.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2TWGV@28211|Alphaproteobacteria,2JPC5@204441|Rhodospirillales	204441|Rhodospirillales	G	Acetyl-coenzyme A transporter 1	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
LZS3_k127_3269677_2	1379698.RBG1_1C00001G1745	2.037e-36	147.0	COG1100@1|root,COG1100@2|Bacteria,2NPDD@2323|unclassified Bacteria	2|Bacteria	K	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
LZS3_k127_3269677_1	1144275.COCOR_03823	8.763e-50	192.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3269677_0	1121459.AQXE01000007_gene611	5.391e-121	400.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2M8C5@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	elongation factor G domain IV	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS3_k127_3283499_2	1075090.GOAMR_20_01620	1.329e-16	87.0	COG1020@1|root,COG1020@2|Bacteria,2IGNH@201174|Actinobacteria,4GFU6@85026|Gordoniaceae	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_3283499_1	425104.Ssed_2247	1.574e-136	447.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,1RMRF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine	patA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R01155,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECIAI1_1343.ECIAI1_3220,iECSF_1327.ECSF_2916,iECs_1301.ECs3955,iZ_1308.Z4426	Aminotran_3
LZS3_k127_3283499_0	502025.Hoch_1494	4.962e-167	551.0	2CC7E@1|root,2Z7WG@2|Bacteria,1R77M@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3290041_0	1254432.SCE1572_34940	0.0	1232.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS3_k127_3290041_1	1403819.BATR01000137_gene4890	0.0005504	53.0	COG1011@1|root,COG1011@2|Bacteria,46T57@74201|Verrucomicrobia,2IUUA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS3_k127_3313550_0	1297742.A176_06899	9.559e-31	138.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
LZS3_k127_3314006_4	1030157.AFMP01000009_gene3656	1.792e-54	197.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,1QV6D@1224|Proteobacteria,2TTB1@28211|Alphaproteobacteria,2K8G7@204457|Sphingomonadales	204457|Sphingomonadales	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3314006_1	1030157.AFMP01000009_gene3655	1.881e-182	579.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,2K3PM@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_3314006_5	1248916.ANFY01000007_gene2330	6.877e-47	178.0	COG1024@1|root,COG1024@2|Bacteria,1MVPQ@1224|Proteobacteria,2TTJ4@28211|Alphaproteobacteria,2K20K@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_3314006_0	383372.Rcas_1863	9.544e-279	873.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi,376PZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
LZS3_k127_3314006_6	383372.Rcas_1862	3.041e-20	93.0	COG1977@1|root,COG1977@2|Bacteria,2G9DU@200795|Chloroflexi,377DC@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS3_k127_3314006_3	1380394.JADL01000018_gene1896	1.206e-55	222.0	2EX4W@1|root,33QFX@2|Bacteria,1NRWJ@1224|Proteobacteria,2UNPH@28211|Alphaproteobacteria,2JVSM@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3314006_2	1123320.KB889585_gene1895	1.491e-146	473.0	COG1960@1|root,COG1960@2|Bacteria,2ICK3@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3314006_7	1268072.PSAB_04300	1.212e-11	76.0	COG1216@1|root,COG1216@2|Bacteria,1UKQU@1239|Firmicutes,4IRE1@91061|Bacilli,276R4@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
LZS3_k127_3315824_2	1131269.AQVV01000032_gene310	9.175e-11	74.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K20306	-	-	-	-	ko00000,ko04131	-	-	-	Lipase_GDSL,Lipase_GDSL_2
LZS3_k127_3315824_0	661478.OP10G_3758	1.605e-188	602.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
LZS3_k127_3315824_1	883078.HMPREF9695_01831	2.166e-100	335.0	COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,2TVBC@28211|Alphaproteobacteria,3JSPF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_3315824_3	338969.Rfer_0524	1.032e-06	53.0	COG3327@1|root,COG3327@2|Bacteria,1RABS@1224|Proteobacteria,2VS49@28216|Betaproteobacteria,4AGRP@80864|Comamonadaceae	28216|Betaproteobacteria	K	PaaX-like protein C-terminal domain	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
LZS3_k127_3333181_2	272943.RSP_3322	7.312e-06	51.0	COG3284@1|root,COG3284@2|Bacteria,1MVRZ@1224|Proteobacteria,2TSRW@28211|Alphaproteobacteria,1FCQP@1060|Rhodobacter	28211|Alphaproteobacteria	K	GAF domain	acoR	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	GAF,HTH_8
LZS3_k127_3333181_0	40373.F991_02347	2.284e-64	241.0	COG3239@1|root,COG3239@2|Bacteria,1MUHK@1224|Proteobacteria,1RYA7@1236|Gammaproteobacteria,3NJ8D@468|Moraxellaceae	1236|Gammaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
LZS3_k127_3333181_1	1415779.JOMH01000001_gene1099	6.085e-29	122.0	COG3327@1|root,COG3327@2|Bacteria,1RABS@1224|Proteobacteria,1S2WE@1236|Gammaproteobacteria,1X6K8@135614|Xanthomonadales	135614|Xanthomonadales	K	PaaX-like protein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PaaX,PaaX_C
LZS3_k127_3335321_0	251221.35211117	3.944e-166	548.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,1G2CB@1117|Cyanobacteria	1117|Cyanobacteria	G	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,Lectin_C
LZS3_k127_3359815_4	1396141.BATP01000021_gene172	1.332e-19	96.0	COG4262@1|root,COG4262@2|Bacteria,46WK6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3359815_3	886293.Sinac_2910	1.127e-44	173.0	COG0596@1|root,COG0596@2|Bacteria,2J1GA@203682|Planctomycetes	203682|Planctomycetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3359815_0	404589.Anae109_3758	1.079e-104	342.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
LZS3_k127_3359815_2	1144275.COCOR_01950	4.287e-58	217.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,2YV9Q@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
LZS3_k127_3359815_1	404589.Anae109_3760	5.189e-65	229.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2YYNH@29|Myxococcales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
LZS3_k127_3359815_5	1121918.ARWE01000001_gene240	7.679e-14	81.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,43SPV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	YbaB/EbfC DNA-binding family	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
LZS3_k127_3359815_6	1121405.dsmv_1578	2.6e-05	53.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2MHZQ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
LZS3_k127_3366326_12	1218075.BAYA01000059_gene7028	2.779e-14	77.0	COG0789@1|root,COG0789@2|Bacteria,1RFQI@1224|Proteobacteria,2VS80@28216|Betaproteobacteria,1K7HC@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
LZS3_k127_3366326_10	748247.AZKH_4232	2.075e-37	150.0	COG3671@1|root,COG3671@2|Bacteria,1N51H@1224|Proteobacteria,2VUKZ@28216|Betaproteobacteria,2KWZK@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3366326_7	349124.Hhal_0101	2.425e-62	219.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1WXZK@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS3_k127_3366326_11	290397.Adeh_0078	1.692e-21	99.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3366326_5	13689.BV96_03926	2.164e-89	308.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2TU8W@28211|Alphaproteobacteria,2K0IC@204457|Sphingomonadales	204457|Sphingomonadales	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_3366326_9	1236959.BAMT01000005_gene21	1.637e-40	162.0	COG5592@1|root,COG5592@2|Bacteria,1RI8J@1224|Proteobacteria,2VS4H@28216|Betaproteobacteria,2KNUH@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
LZS3_k127_3366326_3	1267534.KB906755_gene4103	4.498e-158	532.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
LZS3_k127_3366326_2	1123368.AUIS01000027_gene1350	1.317e-160	528.0	COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,1RPYU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	homoserine dehydrogenase	strU	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_3
LZS3_k127_3366326_8	225937.HP15_1900	6.948e-55	220.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,465GN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rmlC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
LZS3_k127_3366326_4	1286631.X805_32130	1.358e-124	403.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VIQG@28216|Betaproteobacteria	28216|Betaproteobacteria	JM	Glucose-1-phosphate cytidylyltransferase	rfbF	-	2.7.7.33,2.7.7.71	ko:K00978,ko:K15669	ko00500,ko00520,ko00540,ko01100,map00500,map00520,map00540,map01100	-	R00956,R09772	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
LZS3_k127_3366326_1	443598.AUFA01000015_gene6818	3.574e-171	566.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,3JTIE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS3_k127_3366326_0	443598.AUFA01000015_gene6819	1.965e-182	579.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2TRM0@28211|Alphaproteobacteria,3JR0I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	GM	epimerase dehydratase	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS3_k127_3366326_6	443598.AUFA01000015_gene6820	1.539e-83	286.0	COG2120@1|root,COG2120@2|Bacteria,1MX2V@1224|Proteobacteria,2TT5F@28211|Alphaproteobacteria,3JVNZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_3370791_0	471852.Tcur_2580	2.718e-184	598.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_3370791_1	1298863.AUEP01000006_gene3336	4.577e-38	149.0	COG4221@1|root,COG4221@2|Bacteria,2I8VU@201174|Actinobacteria,4DPNG@85009|Propionibacteriales	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_3382766_1	572477.Alvin_2520	4.506e-07	60.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales	135613|Chromatiales	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS3_k127_3382766_0	1337936.IJ00_07850	1.12e-147	497.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G3NP@1117|Cyanobacteria,1HIUE@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
LZS3_k127_338335_2	643562.Daes_0764	1.215e-21	98.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,42TGI@68525|delta/epsilon subdivisions,2WQJU@28221|Deltaproteobacteria,2MBCC@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
LZS3_k127_338335_0	326424.FRAAL5790	7.265e-78	266.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,4ERT5@85013|Frankiales	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
LZS3_k127_338335_1	760568.Desku_2140	8.925e-41	158.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,261ZW@186807|Peptococcaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
LZS3_k127_3387351_0	882083.SacmaDRAFT_3928	7.063e-205	646.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,4DZDX@85010|Pseudonocardiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.3.1.86	ko:K17829	ko00650,ko01120,ko01130,ko01200,map00650,map01120,map01130,map01200	-	R09738	RC00076	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_3387351_1	469383.Cwoe_4214	2.198e-162	520.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	-	-	6.2.1.18	ko:K15232	ko00720,ko01100,ko01120,ko01200,map00720,map01100,map01120,map01200	M00173	R01322	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2
LZS3_k127_3387351_2	1283299.AUKG01000002_gene4334	1.988e-138	445.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CSIF@84995|Rubrobacteria	84995|Rubrobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Succ_CoA_lig
LZS3_k127_3387351_3	502025.Hoch_5221	1.444e-129	432.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,2YTVB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
LZS3_k127_3387351_4	216594.MMAR_1542	1.887e-45	170.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	MA20_16915	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_3,Glyoxalase_4
LZS3_k127_3387439_1	1232410.KI421418_gene2186	6.689e-05	49.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,43SHT@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Recombination protein O C terminal	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
LZS3_k127_3387439_0	880073.Calab_2803	1.221e-156	512.0	COG0423@1|root,COG0423@2|Bacteria,2NNN9@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
LZS3_k127_3389823_0	1266909.AUAG01000054_gene393	4.07e-09	70.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR,Peptidase_S8
LZS3_k127_3400676_2	1123257.AUFV01000003_gene1121	4.507e-28	119.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,1S990@1236|Gammaproteobacteria,1X7H2@135614|Xanthomonadales	135614|Xanthomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
LZS3_k127_3400676_3	390989.JOEG01000001_gene5184	1.042e-19	99.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4DAWX@85008|Micromonosporales	201174|Actinobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
LZS3_k127_3400676_0	290397.Adeh_3956	2.328e-44	169.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3400676_1	291985.CCSI01000003_gene409	2.592e-42	162.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,2K4ZJ@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
LZS3_k127_3400680_0	1333998.M2A_2221	3.834e-121	410.0	COG0625@1|root,COG0625@2|Bacteria,1Q9ND@1224|Proteobacteria,2TT22@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0625 Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
LZS3_k127_3400680_1	1254432.SCE1572_44215	1.008e-96	321.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,42MXW@68525|delta/epsilon subdivisions,2WK94@28221|Deltaproteobacteria,2YWE8@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
LZS3_k127_3404433_0	639282.DEFDS_0343	1.564e-148	483.0	COG0436@1|root,COG0436@2|Bacteria,2GEJ2@200930|Deferribacteres	200930|Deferribacteres	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS3_k127_3404433_1	177437.HRM2_32490	1.16e-99	338.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,42PNZ@68525|delta/epsilon subdivisions,2WM13@28221|Deltaproteobacteria,2MJSE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
LZS3_k127_3412672_0	404589.Anae109_1170	0.0	1198.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2YUJ6@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS3_k127_3412672_1	1123242.JH636434_gene3281	6.219e-73	274.0	COG1024@1|root,COG1024@2|Bacteria,2IZFF@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_3412672_2	290397.Adeh_3956	5.806e-38	151.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_341735_0	134676.ACPL_2123	2.954e-74	254.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4DI2D@85008|Micromonosporales	201174|Actinobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_341735_1	502025.Hoch_0349	2.7e-52	194.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.11,5.4.2.12	ko:K01834,ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
LZS3_k127_341735_2	1403819.BATR01000092_gene2760	4.153e-20	102.0	2DDF4@1|root,2ZHTC@2|Bacteria	2|Bacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
LZS3_k127_3424865_0	316274.Haur_1430	9.67e-63	244.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
LZS3_k127_3426552_0	882083.SacmaDRAFT_5567	1.072e-71	250.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4DYN3@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
LZS3_k127_3426552_1	36809.MAB_3271	1.096e-41	157.0	COG2141@1|root,COG2141@2|Bacteria,2HVKH@201174|Actinobacteria,233F9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_3427799_0	713587.THITH_16340	4.535e-112	373.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1WW3A@135613|Chromatiales	135613|Chromatiales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
LZS3_k127_3427799_2	187272.Mlg_0035	3.562e-16	80.0	COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria,1WZ84@135613|Chromatiales	135613|Chromatiales	H	TIGRFAM thiamine biosynthesis protein ThiS	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS3_k127_3427799_1	290397.Adeh_2518	3.293e-94	315.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,2YUEF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
LZS3_k127_3444456_0	1333998.M2A_1988	4.112e-179	574.0	COG2141@1|root,COG2141@2|Bacteria,1NKS6@1224|Proteobacteria,2TT87@28211|Alphaproteobacteria,4BRU8@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	1.14.13.107	ko:K14733	ko00903,map00903	-	R06398,R09385,R09389,R09393	RC01506	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
LZS3_k127_3444456_1	68260.JOAY01000010_gene419	1.173e-47	177.0	COG1167@1|root,COG1167@2|Bacteria,2GM6I@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	ptsJ	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
LZS3_k127_3451698_5	1144342.PMI40_04177	6.902e-07	59.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,472BF@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS3_k127_3451698_3	1192034.CAP_3786	1.949e-120	394.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,2YUIU@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
LZS3_k127_3451698_0	886293.Sinac_2546	4.686e-172	550.0	COG0019@1|root,COG0019@2|Bacteria,2IX3R@203682|Planctomycetes	203682|Planctomycetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
LZS3_k127_3451698_4	1173025.GEI7407_3302	2.214e-47	181.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1H8P0@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
LZS3_k127_3451698_2	1380390.JIAT01000001_gene5136	1.857e-141	486.0	COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4CR16@84995|Rubrobacteria	84995|Rubrobacteria	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
LZS3_k127_3451698_1	1278073.MYSTI_02771	1.751e-152	494.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,42MN0@68525|delta/epsilon subdivisions,2WMBS@28221|Deltaproteobacteria,2YWEV@29|Myxococcales	28221|Deltaproteobacteria	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
LZS3_k127_3462140_0	443143.GM18_1988	6.731e-154	494.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
LZS3_k127_3462140_9	742159.HMPREF0004_4765	6.961e-07	61.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,2VJ9J@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,Glyco_trans_1_4,NAD_binding_8
LZS3_k127_3462140_8	1173263.Syn7502_00221	4.141e-15	81.0	COG0605@1|root,COG0605@2|Bacteria,1G0N2@1117|Cyanobacteria,1GZSS@1129|Synechococcus	1117|Cyanobacteria	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
LZS3_k127_3462140_7	318161.Sden_3712	6.063e-16	81.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,1SCVB@1236|Gammaproteobacteria,2QCUK@267890|Shewanellaceae	1236|Gammaproteobacteria	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
LZS3_k127_3462140_1	159450.NH14_13160	2.564e-147	480.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1K375@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	zraR	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_3462140_5	1306174.JODP01000006_gene3129	1.742e-22	112.0	COG0745@1|root,COG0745@2|Bacteria,2ISP7@201174|Actinobacteria	1306174.JODP01000006_gene3129|-	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3462140_4	1123508.JH636449_gene7420	1.979e-43	170.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,2IZ70@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
LZS3_k127_3462140_2	1192034.CAP_3789	2.463e-88	318.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42ZDX@68525|delta/epsilon subdivisions,2WU5K@28221|Deltaproteobacteria,2Z2X0@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,RsbRD_N
LZS3_k127_3462140_3	1232410.KI421413_gene478	1.248e-69	259.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,42UYG@68525|delta/epsilon subdivisions,2WR4P@28221|Deltaproteobacteria,43V2Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS3_k127_3462140_6	443144.GM21_3445	6.599e-18	90.0	COG3652@1|root,COG3652@2|Bacteria,1N6QU@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
LZS3_k127_3463110_2	1123360.thalar_02889	1.923e-09	65.0	2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2UVJC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3463110_0	1205680.CAKO01000030_gene4799	1.283e-59	217.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,2JPAB@204441|Rhodospirillales	204441|Rhodospirillales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
LZS3_k127_3463110_1	595537.Varpa_2393	3.154e-17	97.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VPR2@28216|Betaproteobacteria,4ADP5@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_3463110_3	1163617.SCD_n00446	2.242e-07	58.0	COG4243@1|root,COG4243@2|Bacteria,1MW9C@1224|Proteobacteria,2VPG2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3468729_1	1219049.SP5_101_00100	5.175e-12	69.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,2K19H@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS3_k127_3468729_0	1121920.AUAU01000008_gene1560	6.842e-203	654.0	COG1154@1|root,COG1154@2|Bacteria,3Y327@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
LZS3_k127_3471016_0	1125863.JAFN01000001_gene809	1.194e-98	336.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_3475076_1	644282.Deba_1045	1.643e-111	379.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS3_k127_3475076_5	1303518.CCALI_02840	0.0004157	50.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	ko:K05554,ko:K15885	ko01056,ko01130,map01056,map01130	M00778	R09265,R09268	RC02546,RC02547	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Polyketide_cyc,Polyketide_cyc2
LZS3_k127_3475076_3	96561.Dole_0563	1.549e-40	162.0	2A4CF@1|root,30SY3@2|Bacteria,1RFXP@1224|Proteobacteria,42RIM@68525|delta/epsilon subdivisions,2WNS6@28221|Deltaproteobacteria,2MNMZ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
LZS3_k127_3475076_0	404589.Anae109_3091	3.486e-198	650.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
LZS3_k127_3475076_2	391625.PPSIR1_16065	1.847e-65	243.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	CP_0018	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
LZS3_k127_3500357_0	56780.SYN_00640	3.269e-124	413.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2MQ50@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
LZS3_k127_3500357_1	378806.STAUR_5850	3.083e-35	139.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,2YX0Q@29|Myxococcales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
LZS3_k127_3500357_2	378806.STAUR_5849	3.18e-25	109.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria,2YVPB@29|Myxococcales	28221|Deltaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
LZS3_k127_3500357_4	398767.Glov_2607	4.831e-18	93.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2WRDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
LZS3_k127_3500357_3	448385.sce7066	2.766e-22	111.0	COG1506@1|root,COG1506@2|Bacteria,1R0DH@1224|Proteobacteria	1224|Proteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
LZS3_k127_3501429_4	391625.PPSIR1_06823	5.735e-05	51.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YY04@29|Myxococcales	28221|Deltaproteobacteria	KT	GAF domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
LZS3_k127_3501429_0	981223.AIED01000040_gene3680	7.608e-103	343.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,3NJA7@468|Moraxellaceae	1236|Gammaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.7.2.8	ko:K00930,ko:K22478	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00259,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_2508,iB21_1397.B21_03793,iEC55989_1330.EC55989_4441,iECB_1328.ECB_03844,iECDH10B_1368.ECDH10B_4147,iECDH1ME8569_1439.ECDH1ME8569_3827,iECD_1391.ECD_03844,iECH74115_1262.ECH74115_5419,iECIAI1_1343.ECIAI1_4167,iECO103_1326.ECO103_4715,iECOK1_1307.ECOK1_4431,iECS88_1305.ECS88_4414,iECSE_1348.ECSE_4252,iETEC_1333.ETEC_4227,iEcE24377_1341.EcE24377A_4498,iEcHS_1320.EcHS_A4193,iEcolC_1368.EcolC_4057,iSbBS512_1146.SbBS512_E4445,iUMN146_1321.UM146_20050,iUMNK88_1353.UMNK88_4797,iUTI89_1310.UTI89_C4550,iY75_1357.Y75_RS17255	AA_kinase,NAT
LZS3_k127_3501429_1	326427.Cagg_2339	1.675e-90	324.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi,3765Z@32061|Chloroflexia	32061|Chloroflexia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS3_k127_3501429_2	1330700.JQNC01000001_gene2205	6.761e-20	97.0	COG3744@1|root,COG3744@2|Bacteria,1WK7R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS3_k127_3501429_3	1207063.P24_04230	1.207e-05	49.0	COG2161@1|root,COG2161@2|Bacteria,1R2Q0@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
LZS3_k127_3516791_9	1301098.PKB_4249	4.472e-56	199.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,1S9S5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3516791_3	1245471.PCA10_13800	5.048e-102	339.0	COG1028@1|root,COG1028@2|Bacteria,1P1U4@1224|Proteobacteria,1RR3M@1236|Gammaproteobacteria,1YJ2B@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_3516791_2	420324.KI912037_gene2397	1.995e-138	454.0	COG1073@1|root,COG2114@1|root,COG1073@2|Bacteria,COG2114@2|Bacteria,1QWKB@1224|Proteobacteria,2TX0H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE,Guanylate_cyc,Hydrolase_4
LZS3_k127_3516791_4	582899.Hden_2200	1.759e-91	312.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2TQRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_3516791_8	1304885.AUEY01000047_gene84	2.577e-57	206.0	29CZA@1|root,2ZZXB@2|Bacteria,1RFNE@1224|Proteobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3516791_6	1219035.NT2_08_01320	9.078e-86	296.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,2K3NY@204457|Sphingomonadales	204457|Sphingomonadales	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_3516791_7	83406.HDN1F_02500	1.047e-64	225.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,1S0DD@1236|Gammaproteobacteria,1J5PB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl dehydratase	nodN	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
LZS3_k127_3516791_5	40571.JOEA01000009_gene3383	3.142e-91	340.0	COG1028@1|root,COG1028@2|Bacteria,2GN3D@201174|Actinobacteria,4E0YS@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_3516791_1	1149133.ppKF707_2639	1.162e-163	530.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPZ9@1236|Gammaproteobacteria,1YIBT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3516791_0	1301098.PKB_4315	5.384e-214	684.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_3516791_10	1283299.AUKG01000002_gene5035	3.698e-31	127.0	COG3945@1|root,COG3945@2|Bacteria,2I4J6@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
LZS3_k127_3521217_0	246197.MXAN_3504	5.565e-23	107.0	COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2Z1RM@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3521217_1	68570.DC74_6642	2.29e-16	88.0	COG2340@1|root,COG2340@2|Bacteria,2IE0J@201174|Actinobacteria	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
LZS3_k127_3552917_1	1237500.ANBA01000023_gene5018	2.339e-41	159.0	COG3467@1|root,COG3467@2|Bacteria,2IIAS@201174|Actinobacteria,4EKI3@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
LZS3_k127_3552917_2	1196083.SALWKB12_1943	3.426e-16	87.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,2KRP7@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
LZS3_k127_3552917_0	1041930.Mtc_0688	7.316e-84	289.0	COG4992@1|root,arCOG00914@2157|Archaea,2XTKV@28890|Euryarchaeota,2N98X@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_3561787_0	203119.Cthe_1007	5.041e-205	654.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3WGEU@541000|Ruminococcaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
LZS3_k127_3561787_1	1297742.A176_04163	4.489e-79	273.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YUTC@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS3_k127_3572351_0	234267.Acid_3577	5.169e-74	255.0	COG0249@1|root,COG0249@2|Bacteria,3Y48T@57723|Acidobacteria	57723|Acidobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
LZS3_k127_3572351_1	1419583.V466_16805	3.033e-11	75.0	COG1409@1|root,COG1409@2|Bacteria,1NXRI@1224|Proteobacteria,1S1N6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Acid phosphatase	-	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
LZS3_k127_3572351_2	1403819.BATR01000112_gene3845	5.668e-09	68.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	arnT	-	2.4.2.43	ko:K07264	ko01503,map01503	M00721	R09773,R09774,R09781	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	-	PMT,PMT_2
LZS3_k127_3574524_2	1101189.AQUO01000002_gene492	1.931e-10	74.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2TU59@28211|Alphaproteobacteria,2PV71@265|Paracoccus	28211|Alphaproteobacteria	V	ABC-2 family transporter protein	MA20_09460	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS3_k127_3574524_1	666685.R2APBS1_2948	1.526e-37	162.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1X3TB@135614|Xanthomonadales	135614|Xanthomonadales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS3_k127_3574524_0	518766.Rmar_1780	6.389e-65	235.0	COG1131@1|root,COG1131@2|Bacteria,4NFW9@976|Bacteroidetes,1FIPW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_3581391_1	378806.STAUR_6465	2.004e-39	164.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1MVCU@1224|Proteobacteria,42N57@68525|delta/epsilon subdivisions,2WJ82@28221|Deltaproteobacteria,2YX92@29|Myxococcales	28221|Deltaproteobacteria	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2,RNase_T,ResIII
LZS3_k127_3581391_0	644966.Tmar_1342	1.997e-163	531.0	COG0028@1|root,COG0028@2|Bacteria,1UYHG@1239|Firmicutes,24FP1@186801|Clostridia	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_359860_1	584708.Apau_2405	4.894e-33	145.0	COG2110@1|root,COG2110@2|Bacteria,3TB5Z@508458|Synergistetes	508458|Synergistetes	S	C-terminal domain of histone	-	-	-	-	-	-	-	-	-	-	-	-	Macro
LZS3_k127_359860_0	177437.HRM2_35930	1.459e-100	340.0	COG1899@1|root,COG1899@2|Bacteria,1R3WQ@1224|Proteobacteria,42M57@68525|delta/epsilon subdivisions,2WJ6N@28221|Deltaproteobacteria,2MHW7@213118|Desulfobacterales	28221|Deltaproteobacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_360202_0	237368.SCABRO_00780	7.052e-41	170.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_3610751_4	1238182.C882_1024	4.563e-23	102.0	COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,2UCCK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_3610751_6	717773.Thicy_1110	5.238e-19	97.0	2E8DE@1|root,332RW@2|Bacteria,1N96Q@1224|Proteobacteria,1TATG@1236|Gammaproteobacteria,462WE@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3610751_0	1089547.KB913013_gene439	8.435e-209	664.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
LZS3_k127_3610751_3	945713.IALB_0721	5.225e-56	222.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	ccoO	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600	1.9.3.1	ko:K00404,ko:K00405,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144,iIT341.HP0145	COX1,FixO
LZS3_k127_3610751_5	1408433.JHXV01000049_gene1899	5.639e-22	106.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1HZ3Y@117743|Flavobacteriia,2PAXX@246874|Cryomorphaceae	976|Bacteroidetes	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit III	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
LZS3_k127_3610751_1	246197.MXAN_5538	1.607e-88	311.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2WNZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
LZS3_k127_3610751_2	1232410.KI421424_gene1642	7.908e-74	265.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WMJD@28221|Deltaproteobacteria,43UCJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Putative metal-binding domain of cation transport ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
LZS3_k127_3615735_0	1121935.AQXX01000066_gene2370	2.561e-06	60.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR,Glyco_hydro_16
LZS3_k127_3618283_1	1242864.D187_000606	4.402e-20	90.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2X24A@28221|Deltaproteobacteria,2Z1T0@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_3618283_0	1142394.PSMK_18670	0.0	1251.0	COG1048@1|root,COG1048@2|Bacteria,2IY29@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
LZS3_k127_363105_1	402777.KB235904_gene3959	5.213e-69	242.0	COG0697@1|root,COG0697@2|Bacteria,1G29Y@1117|Cyanobacteria,1H9R1@1150|Oscillatoriales	1117|Cyanobacteria	EG	Drug metabolite transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_363105_0	1168065.DOK_05550	2.855e-107	362.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,1T3IW@1236|Gammaproteobacteria,1J86D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_363105_2	1192034.CAP_3175	8.348e-66	251.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,43AER@68525|delta/epsilon subdivisions,2X5UG@28221|Deltaproteobacteria,2YUH1@29|Myxococcales	28221|Deltaproteobacteria	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,NHL,RHS_repeat
LZS3_k127_364085_1	1313172.YM304_07200	3.09e-33	147.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria	201174|Actinobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
LZS3_k127_364085_0	234267.Acid_5780	5.055e-57	221.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
LZS3_k127_3686791_1	1123320.KB889585_gene1895	2.972e-175	571.0	COG1960@1|root,COG1960@2|Bacteria,2ICK3@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3686791_3	1123320.KB889585_gene1894	4.121e-141	458.0	COG1804@1|root,COG1804@2|Bacteria,2IEU2@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_3686791_6	479433.Caci_5358	8.407e-60	236.0	COG2030@1|root,COG2030@2|Bacteria,2ICZR@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
LZS3_k127_3686791_5	479433.Caci_5359	4.155e-61	223.0	COG2030@1|root,COG2030@2|Bacteria,2IPFP@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
LZS3_k127_3686791_2	1123320.KB889585_gene1891	6.025e-147	473.0	COG1960@1|root,COG1960@2|Bacteria,2I8MN@201174|Actinobacteria	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_3686791_0	1123320.KB889585_gene1796	2.538e-182	597.0	COG1804@1|root,COG1804@2|Bacteria,2I8ZJ@201174|Actinobacteria	201174|Actinobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_3686791_7	717774.Marme_1713	5.162e-12	72.0	2AEMB@1|root,314H8@2|Bacteria,1QSBT@1224|Proteobacteria,1SQG9@1236|Gammaproteobacteria,1XPS0@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
LZS3_k127_3686791_4	1116232.AHBF01000084_gene7630	5.645e-97	332.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_3704177_1	1301098.PKB_4319	1.567e-95	342.0	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RQZ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	kshB	-	1.14.13.142	ko:K02613,ko:K15983	ko00360,ko00984,ko01100,ko01120,map00360,map00984,map01100,map01120	-	R09838,R09860	RC02690,RC02691	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1
LZS3_k127_3704177_0	1382306.JNIM01000001_gene3950	1.415e-115	386.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
LZS3_k127_3704566_1	1123242.JH636434_gene3585	9.014e-07	58.0	COG1595@1|root,COG1595@2|Bacteria,2J0K1@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
LZS3_k127_3704566_0	1254432.SCE1572_19595	3.774e-46	187.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,438BB@68525|delta/epsilon subdivisions,2X3KN@28221|Deltaproteobacteria,2YWFV@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_3716643_0	1123242.JH636434_gene4081	2.404e-302	936.0	COG0422@1|root,COG0422@2|Bacteria,2IWV7@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
LZS3_k127_3716643_1	1166018.FAES_0539	9.67e-21	105.0	COG4857@1|root,COG4857@2|Bacteria,4NHKI@976|Bacteroidetes,47JME@768503|Cytophagia	976|Bacteroidetes	S	Phosphotransferase enzyme family	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
LZS3_k127_3735664_2	338963.Pcar_3065	5.013e-19	95.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43SCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
LZS3_k127_3735664_0	1232410.KI421412_gene411	8.469e-90	320.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS3_k127_3735664_1	1469245.JFBG01000002_gene466	3.519e-22	97.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1WVWF@135613|Chromatiales	135613|Chromatiales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
LZS3_k127_3737378_5	570268.ANBB01000046_gene1431	1.354e-55	212.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4EHK1@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_3737378_7	1151061.CAJY01000033_gene1942	1.451e-40	165.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.3.1.1	ko:K00537,ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,ArsC,C_GCAxxG_C_C
LZS3_k127_3737378_0	1382356.JQMP01000001_gene875	9.245e-102	347.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,27Z35@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_3737378_9	345341.KUTG_04140	5.509e-10	65.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3737378_8	446470.Snas_1947	1.836e-21	104.0	COG1733@1|root,COG3255@1|root,COG1733@2|Bacteria,COG3255@2|Bacteria,2GMK5@201174|Actinobacteria,4EYGH@85014|Glycomycetales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
LZS3_k127_3737378_3	316274.Haur_0959	8.16e-92	316.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3737378_1	96561.Dole_3102	5.055e-100	341.0	COG1960@1|root,COG1960@2|Bacteria,1NCCF@1224|Proteobacteria,42YB2@68525|delta/epsilon subdivisions,2WUMQ@28221|Deltaproteobacteria,2MMJJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
LZS3_k127_3737378_2	570268.ANBB01000057_gene4149	1.833e-94	336.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4EGJ1@85012|Streptosporangiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
LZS3_k127_3737378_6	556268.OFAG_00103	1.067e-48	178.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,4741A@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
LZS3_k127_3737378_4	1278073.MYSTI_03678	1.152e-57	208.0	COG1024@1|root,COG1024@2|Bacteria,1MWGT@1224|Proteobacteria,4314E@68525|delta/epsilon subdivisions,2WWTK@28221|Deltaproteobacteria,2Z3AC@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_3743719_1	1192034.CAP_4015	2.353e-23	117.0	COG1073@1|root,COG1073@2|Bacteria,1NKA5@1224|Proteobacteria,438I9@68525|delta/epsilon subdivisions,2X9SF@28221|Deltaproteobacteria,2YX1V@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3743719_0	886293.Sinac_1560	2.951e-138	449.0	COG1132@1|root,COG1132@2|Bacteria,2IYCU@203682|Planctomycetes	2|Bacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
LZS3_k127_3784343_1	563192.HMPREF0179_02558	1.333e-23	107.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2M8H0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS3_k127_3813152_1	1121033.AUCF01000026_gene2973	1.165e-61	220.0	COG2191@1|root,COG2191@2|Bacteria,1RD60@1224|Proteobacteria,2U4T2@28211|Alphaproteobacteria,2JWWZ@204441|Rhodospirillales	204441|Rhodospirillales	C	Formylmethanofuran dehydrogenase, subunit e	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3813152_0	1123261.AXDW01000001_gene1115	3.539e-83	295.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,1T0YG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3813152_2	1137799.GZ78_16070	5.151e-14	81.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1XMWY@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
LZS3_k127_381903_0	472759.Nhal_2864	4.665e-66	232.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRA1@1236|Gammaproteobacteria,1WWUF@135613|Chromatiales	135613|Chromatiales	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS3_k127_3831828_4	479434.Sthe_2018	1.329e-21	104.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,27Y04@189775|Thermomicrobia	189775|Thermomicrobia	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS3_k127_3831828_1	1429916.X566_04075	8.78e-167	533.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,3JU2P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3831828_3	1122604.JONR01000048_gene1010	1.961e-46	178.0	COG1309@1|root,COG1309@2|Bacteria,1MV2V@1224|Proteobacteria,1SZ3F@1236|Gammaproteobacteria,1X6R6@135614|Xanthomonadales	135614|Xanthomonadales	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
LZS3_k127_3831828_0	1120936.KB907217_gene3684	6.864e-236	751.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4EHDG@85012|Streptosporangiales	201174|Actinobacteria	I	Carboxyl transferase domain	accD2	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
LZS3_k127_3831828_2	1429046.RR21198_5874	9.315e-143	468.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,4FWEF@85025|Nocardiaceae	201174|Actinobacteria	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
LZS3_k127_3846717_1	671143.DAMO_0676	4.612e-40	156.0	COG0815@1|root,COG0815@2|Bacteria,2NP0R@2323|unclassified Bacteria	2|Bacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS3_k127_3846717_0	1158318.ATXC01000001_gene1139	4.169e-112	372.0	COG1186@1|root,COG1186@2|Bacteria,2G3P3@200783|Aquificae	200783|Aquificae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS3_k127_3847115_2	706587.Desti_3865	1.214e-06	55.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WJ0U@28221|Deltaproteobacteria,2MQ46@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS3_k127_3847115_1	187272.Mlg_1686	4.906e-11	69.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1S5VA@1236|Gammaproteobacteria,1WXYI@135613|Chromatiales	135613|Chromatiales	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
LZS3_k127_3847115_0	234267.Acid_4232	1.825e-164	542.0	COG1138@1|root,COG1138@2|Bacteria,3Y40N@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
LZS3_k127_384780_0	926550.CLDAP_12240	6.467e-298	950.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G6K4@200795|Chloroflexi	200795|Chloroflexi	H	phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS3_k127_384780_1	867845.KI911784_gene1685	5.958e-105	351.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS3_k127_384780_2	1184607.AUCHE_05_04270	4.887e-104	344.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,2I995@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS3_k127_3895861_0	667014.Thein_1737	7.407e-107	356.0	COG0382@1|root,COG0382@2|Bacteria,2GI94@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
LZS3_k127_393397_1	1121106.JQKB01000055_gene5579	2.709e-69	243.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TVBB@28211|Alphaproteobacteria,2JZCU@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_393397_0	1125863.JAFN01000001_gene1119	1.922e-79	278.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
LZS3_k127_3934721_3	290397.Adeh_0236	0.0002544	44.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2YVCY@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
LZS3_k127_3934721_0	1232410.KI421412_gene402	2.386e-169	556.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,43T5X@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
LZS3_k127_3934721_1	1492922.GY26_12530	4.621e-26	115.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
LZS3_k127_3934721_2	243231.GSU3210	1.45e-10	64.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,43TVZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
LZS3_k127_3940539_0	1283300.ATXB01000002_gene2962	3.108e-204	664.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1XENZ@135618|Methylococcales	135618|Methylococcales	S	ABC transporter C-terminal domain	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS3_k127_3940539_1	404589.Anae109_1819	3.814e-73	257.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
LZS3_k127_3960895_3	247634.GPB2148_1970	3.279e-12	70.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,1RMNY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	ydjJ	-	1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4,1.1.1.9	ko:K00004,ko:K00008,ko:K05351,ko:K08322	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	M00014	R00875,R01896,R02855,R02946,R10504,R10848	RC00085,RC00102,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_3960895_0	1243664.CAVL020000045_gene2121	7.992e-150	484.0	COG1960@1|root,COG1960@2|Bacteria,1UK89@1239|Firmicutes,4HAR5@91061|Bacilli,1ZE5H@1386|Bacillus	91061|Bacilli	I	COG1960 Acyl-CoA dehydrogenases	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3960895_1	1123072.AUDH01000033_gene1983	6.276e-71	247.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2TUHN@28211|Alphaproteobacteria,2JS08@204441|Rhodospirillales	204441|Rhodospirillales	H	ABC-type tungstate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
LZS3_k127_3960895_2	1244869.H261_13154	1.765e-18	88.0	COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2TSCU@28211|Alphaproteobacteria,2JRVW@204441|Rhodospirillales	204441|Rhodospirillales	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS3_k127_396337_2	1121396.KB892957_gene3252	4.543e-47	176.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,42TER@68525|delta/epsilon subdivisions,2WPKW@28221|Deltaproteobacteria,2MK8J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
LZS3_k127_396337_3	420324.KI911972_gene3029	4.211e-33	141.0	COG1999@1|root,COG1999@2|Bacteria,1N6WC@1224|Proteobacteria,2VFHX@28211|Alphaproteobacteria	1224|Proteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	AhpC-TSA,SCO1-SenC
LZS3_k127_396337_4	1144672.F966_00163	1.066e-08	66.0	COG5569@1|root,COG5569@2|Bacteria,1NGSZ@1224|Proteobacteria,1SGPW@1236|Gammaproteobacteria,3NNQR@468|Moraxellaceae	1236|Gammaproteobacteria	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07810	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.6.1.4	-	-	CusF_Ec
LZS3_k127_396337_0	247634.GPB2148_479	3.913e-123	424.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1J4GG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	tas	GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_396337_1	1095769.CAHF01000017_gene17	7.224e-94	324.0	COG4257@1|root,COG4257@2|Bacteria,1R448@1224|Proteobacteria,2W139@28216|Betaproteobacteria	28216|Betaproteobacteria	V	COG4257 Streptogramin lyase	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	CarboxypepD_reg
LZS3_k127_3963732_0	926569.ANT_28670	2.437e-145	473.0	COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS3_k127_3963732_2	639030.JHVA01000001_gene1310	6.209e-89	304.0	COG0158@1|root,COG0158@2|Bacteria,3Y70S@57723|Acidobacteria,2JKY5@204432|Acidobacteriia	204432|Acidobacteriia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
LZS3_k127_3963732_1	502025.Hoch_3149	7.02e-106	368.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YWIW@29|Myxococcales	28221|Deltaproteobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
LZS3_k127_3982666_3	1203554.HMPREF1476_02113	4.648e-14	83.0	COG0515@1|root,COG0515@2|Bacteria,1N75K@1224|Proteobacteria,2W05P@28216|Betaproteobacteria,4PQYC@995019|Sutterellaceae	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3982666_1	401053.AciPR4_3583	1.864e-16	89.0	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria,2JJ89@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_3982666_2	314260.PB2503_11699	6.727e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2TVKC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	MA20_22745	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
LZS3_k127_3982666_0	243231.GSU0580	0.0	1157.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43TQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS3_k127_3993099_5	582402.Hbal_0078	5.249e-18	85.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,2UAWF@28211|Alphaproteobacteria,43X26@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
LZS3_k127_3993099_2	562970.Btus_0350	1.052e-77	274.0	COG1960@1|root,COG1960@2|Bacteria,1TPVK@1239|Firmicutes,4HA7B@91061|Bacilli,278UF@186823|Alicyclobacillaceae	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	B4168_2380	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_3993099_4	1381751.JAJB01000035_gene648	1.329e-28	133.0	COG0461@1|root,COG0461@2|Bacteria,2GKUQ@201174|Actinobacteria,4F9EH@85019|Brevibacteriaceae	201174|Actinobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS3_k127_3993099_1	1382356.JQMP01000004_gene488	3.511e-285	887.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
LZS3_k127_3993099_0	269796.Rru_A1606	1.849e-293	955.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2TRVS@28211|Alphaproteobacteria,2JQKB@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS3_k127_3993099_3	1333856.L686_08230	1.333e-36	150.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1S2R7@1236|Gammaproteobacteria,1Z2V1@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
LZS3_k127_4003480_0	187272.Mlg_1309	1.492e-28	118.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1WWQ4@135613|Chromatiales	135613|Chromatiales	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
LZS3_k127_4021980_0	404380.Gbem_0159	8.039e-168	546.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
LZS3_k127_4033224_0	671143.DAMO_0105	2.331e-90	309.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	atoC	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_4033224_1	78245.Xaut_1075	2.518e-11	75.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VEXA@28211|Alphaproteobacteria,3F174@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_4044094_1	1167006.UWK_02223	2.651e-73	272.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2MHS5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS3_k127_4044094_0	1499967.BAYZ01000139_gene140	2.38e-78	287.0	COG1680@1|root,COG1680@2|Bacteria,2NPA1@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
LZS3_k127_4044094_2	292459.STH2808	3.422e-62	224.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia	186801|Clostridia	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
LZS3_k127_4057215_6	1396418.BATQ01000151_gene2293	1.774e-49	186.0	COG0500@1|root,COG2226@2|Bacteria,46XQZ@74201|Verrucomicrobia,2IWE6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_4057215_3	1304872.JAGC01000003_gene2874	3.797e-129	424.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,42ZMZ@68525|delta/epsilon subdivisions,2X27A@28221|Deltaproteobacteria,2M8TC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_4057215_1	234267.Acid_2163	7.522e-157	526.0	COG1215@1|root,COG1215@2|Bacteria,3Y74D@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_4057215_2	1313172.YM304_32850	1.517e-134	440.0	COG0451@1|root,COG0451@2|Bacteria,2GP0W@201174|Actinobacteria	201174|Actinobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
LZS3_k127_4057215_5	1197906.CAJQ02000023_gene2169	1.247e-57	226.0	COG2520@1|root,COG2520@2|Bacteria,1RK9Q@1224|Proteobacteria	1224|Proteobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
LZS3_k127_4057215_7	1122201.AUAZ01000009_gene2847	2.692e-28	120.0	COG3584@1|root,COG3584@2|Bacteria,1MZPJ@1224|Proteobacteria,1SBH0@1236|Gammaproteobacteria,46BSK@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	3D domain protein	DR0488	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4057215_11	765911.Thivi_2564	6.681e-05	45.0	2E3KF@1|root,32YIQ@2|Bacteria,1NC3P@1224|Proteobacteria,1SD8X@1236|Gammaproteobacteria,1WZDZ@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4057215_4	1121033.AUCF01000004_gene5015	6.096e-59	226.0	COG2982@1|root,COG2982@2|Bacteria,1QY0F@1224|Proteobacteria,2TY3Y@28211|Alphaproteobacteria,2JYZF@204441|Rhodospirillales	204441|Rhodospirillales	M	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
LZS3_k127_4057215_9	1197719.A464_1682	2.818e-12	80.0	2E371@1|root,32Y6T@2|Bacteria,1N8D8@1224|Proteobacteria,1SCAF@1236|Gammaproteobacteria,3ZMNK@590|Salmonella	1236|Gammaproteobacteria	M	YnbE-like lipoprotein	ynbE	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
LZS3_k127_4057215_8	1122951.ATUE01000007_gene812	6.161e-20	97.0	COG3784@1|root,COG3784@2|Bacteria,1N6R1@1224|Proteobacteria,1SC8V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ydbL	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
LZS3_k127_4057215_0	450851.PHZ_p0170	5.795e-207	658.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,2KIPI@204458|Caulobacterales	204458|Caulobacterales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.321	ko:K13688,ko:K18786	-	-	R10832	RC00397	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36
LZS3_k127_405834_0	1121124.JNIX01000005_gene1281	3.411e-28	127.0	2E0BU@1|root,32VYY@2|Bacteria,1N1HC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_405834_2	1144275.COCOR_08067	3.03e-05	57.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2WKGT@28221|Deltaproteobacteria,2YYF0@29|Myxococcales	28221|Deltaproteobacteria	S	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
LZS3_k127_4066151_5	1532557.JL37_13475	2.006e-64	247.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VN0B@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-transferase family III	bbsE	-	2.8.3.15	ko:K07543	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
LZS3_k127_4066151_4	1348657.M622_02740	4.115e-82	297.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2VHSP@28216|Betaproteobacteria,2KYCR@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_4066151_3	357808.RoseRS_1121	1.078e-89	328.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,376CU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_4066151_0	1301098.PKB_4330	5.89e-190	611.0	COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,1RNYN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Succinate dehydrogenase fumarate reductase, flavoprotein subunit	-	-	1.3.99.4	ko:K05898	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09884	RC00991	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
LZS3_k127_4066151_6	1348657.M622_05000	5.417e-50	186.0	COG2010@1|root,COG2010@2|Bacteria,1PE1B@1224|Proteobacteria,2W4M1@28216|Betaproteobacteria,2KZ62@206389|Rhodocyclales	206389|Rhodocyclales	C	Ethylbenzene dehydrogenase	-	-	-	ko:K17052	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	EB_dh
LZS3_k127_4066151_1	1348657.M622_05005	2.678e-179	579.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,2VJ1V@28216|Betaproteobacteria,2KVJ5@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S dicluster domain	-	-	-	ko:K17048,ko:K17051	ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220	-	R05745	RC00275	ko00000,ko00001,ko02000	5.A.3.8,5.A.3.9	-	-	Fer4_11
LZS3_k127_4066151_2	1348657.M622_05010	1.116e-101	346.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,2WGS4@28216|Betaproteobacteria,2KU8N@206389|Rhodocyclales	206389|Rhodocyclales	C	Molydopterin dinucleotide binding domain	-	-	1.17.99.2	ko:K10700,ko:K17050	ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220	-	R05745	RC00275	ko00000,ko00001,ko01000,ko02000	5.A.3.8,5.A.3.9	-	-	Molybdopterin,Molydop_binding
LZS3_k127_409221_2	1385519.N801_17210	2.86e-08	63.0	2EVIQ@1|root,33NYW@2|Bacteria,2IIIZ@201174|Actinobacteria	201174|Actinobacteria	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
LZS3_k127_409221_0	234267.Acid_4518	2.29e-24	119.0	2ANCT@1|root,31DBC@2|Bacteria,3Y69A@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
LZS3_k127_409221_1	56107.Cylst_1538	1.174e-16	83.0	COG3225@1|root,COG3225@2|Bacteria,1G0JN@1117|Cyanobacteria,1HMIS@1161|Nostocales	1117|Cyanobacteria	N	transport system involved in gliding motility, auxiliary component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
LZS3_k127_4116557_0	309801.trd_1931	0.0	1366.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
LZS3_k127_4116557_1	448385.sce0351	3.38e-37	163.0	COG1640@1|root,COG1640@2|Bacteria,1QTDU@1224|Proteobacteria,437WN@68525|delta/epsilon subdivisions,2X36B@28221|Deltaproteobacteria,2YUHJ@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-glucanotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_77
LZS3_k127_4120453_2	1380390.JIAT01000009_gene1919	2.249e-52	197.0	2AV96@1|root,31M03@2|Bacteria,2HPQD@201174|Actinobacteria,4CR3C@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4120453_1	926562.Oweho_2055	1.256e-54	210.0	COG2982@1|root,COG2982@2|Bacteria,4NIE2@976|Bacteroidetes,1HZC9@117743|Flavobacteriia,2PAV2@246874|Cryomorphaceae	976|Bacteroidetes	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
LZS3_k127_4120453_0	1173024.KI912149_gene5907	1.717e-73	265.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1JGV5@1189|Stigonemataceae	1117|Cyanobacteria	S	Virulence factor BrkB	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS3_k127_4120453_5	1219045.BV98_002485	2.788e-19	90.0	COG3668@1|root,32ZH9@2|Bacteria,1N7YH@1224|Proteobacteria,2UC0X@28211|Alphaproteobacteria,2K645@204457|Sphingomonadales	204457|Sphingomonadales	S	Plasmid stabilization	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4120453_6	187303.BN69_2422	2.154e-13	84.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
LZS3_k127_4120453_3	1123255.JHYS01000017_gene1388	3.492e-42	163.0	COG4273@1|root,COG4273@2|Bacteria,1MZED@1224|Proteobacteria,2VV77@28216|Betaproteobacteria,4AEQ0@80864|Comamonadaceae	28216|Betaproteobacteria	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
LZS3_k127_4120453_4	402777.KB235904_gene2694	3.899e-32	145.0	COG1807@1|root,COG1807@2|Bacteria,1GI8H@1117|Cyanobacteria,1HETH@1150|Oscillatoriales	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_4132825_0	706587.Desti_2026	1.354e-114	388.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Spermine spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
LZS3_k127_4133239_5	648996.Theam_1352	6.553e-18	93.0	COG4968@1|root,COG4968@2|Bacteria,2G5IB@200783|Aquificae	200783|Aquificae	NU	Pfam:N_methyl_2	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
LZS3_k127_4133239_4	215803.DB30_5163	3.422e-21	105.0	COG0457@1|root,COG0457@2|Bacteria,1MZCR@1224|Proteobacteria,42R7I@68525|delta/epsilon subdivisions,2WMT6@28221|Deltaproteobacteria,2YW4K@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	pilG	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4133239_0	290397.Adeh_0636	4.879e-73	276.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YXY8@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_4133239_3	118163.Ple7327_3746	1.253e-42	177.0	COG1277@1|root,COG1277@2|Bacteria,1G09F@1117|Cyanobacteria,3VIM9@52604|Pleurocapsales	1117|Cyanobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
LZS3_k127_4133239_2	316067.Geob_3081	1.339e-48	184.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
LZS3_k127_4133239_1	1123242.JH636435_gene833	2.047e-72	259.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
LZS3_k127_4144905_2	1121272.KB903249_gene1700	2.007e-15	92.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2GJYH@201174|Actinobacteria,4DBUI@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
LZS3_k127_4144905_0	251221.35211117	9.193e-164	560.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,1G2CB@1117|Cyanobacteria	1117|Cyanobacteria	G	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,Laminin_G_3,Lectin_C
LZS3_k127_4144905_1	404589.Anae109_4442	2.618e-21	109.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
LZS3_k127_4162521_0	1267535.KB906767_gene3770	6.813e-47	177.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS3_k127_4162521_1	177437.HRM2_09660	2.959e-44	168.0	COG0697@1|root,COG2371@1|root,COG0697@2|Bacteria,COG2371@2|Bacteria,1N3FA@1224|Proteobacteria,42RW0@68525|delta/epsilon subdivisions,2WNEH@28221|Deltaproteobacteria,2MMWS@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_4164038_3	335543.Sfum_2006	7.89e-32	144.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2WJAU@28221|Deltaproteobacteria,2MQKF@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_9,Response_reg
LZS3_k127_4164038_2	690850.Desaf_1136	6.055e-69	241.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2M9HT@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_4164038_5	583355.Caka_1725	1.313e-28	124.0	COG3952@1|root,COG3952@2|Bacteria	2|Bacteria	S	lipid-A-disaccharide synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
LZS3_k127_4164038_0	1192034.CAP_7313	2.211e-166	566.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
LZS3_k127_4164038_1	269084.syc0444_d	5.635e-117	393.0	COG0489@1|root,COG0489@2|Bacteria,1G1I7@1117|Cyanobacteria,1GZNR@1129|Synechococcus	1117|Cyanobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
LZS3_k127_4164038_4	1340493.JNIF01000003_gene1667	4.19e-31	131.0	COG0351@1|root,COG0351@2|Bacteria,3Y4DB@57723|Acidobacteria	57723|Acidobacteria	H	TIGRFAM Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
LZS3_k127_4165318_0	2055.JNXA01000007_gene951	2.067e-25	110.0	COG1804@1|root,COG1804@2|Bacteria,2GMIW@201174|Actinobacteria,4GFVG@85026|Gordoniaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_4170929_0	323848.Nmul_A1604	7.297e-110	368.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,3720W@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
LZS3_k127_4170929_2	161156.JQKW01000012_gene110	5.426e-19	96.0	COG1399@1|root,COG1399@2|Bacteria,2GHV8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
LZS3_k127_4170929_3	644966.Tmar_0944	1.676e-13	81.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3WCP9@538999|Clostridiales incertae sedis	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
LZS3_k127_4170929_1	1356854.N007_03215	2.154e-50	184.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,2784M@186823|Alicyclobacillaceae	91061|Bacilli	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
LZS3_k127_4178962_3	1121920.AUAU01000015_gene1129	3.543e-50	199.0	COG3647@1|root,COG3647@2|Bacteria,3Y8PM@57723|Acidobacteria	57723|Acidobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2238
LZS3_k127_4178962_5	1229780.BN381_450062	3.576e-29	126.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS3_k127_4178962_4	1123400.KB904755_gene2629	7.608e-35	138.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,1S8J5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Domain of unknown function (DUF1924)	shp	-	-	-	-	-	-	-	-	-	-	-	DUF1924
LZS3_k127_4178962_6	580332.Slit_2568	2.958e-21	99.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Di-haem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
LZS3_k127_4178962_2	626418.bglu_2g10710	1.1e-64	236.0	COG2217@1|root,COG3658@1|root,COG2217@2|Bacteria,COG3658@2|Bacteria,1MU08@1224|Proteobacteria,2VMIN@28216|Betaproteobacteria,1K4WF@119060|Burkholderiaceae	28216|Betaproteobacteria	P	p-type atpase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
LZS3_k127_4178962_1	395494.Galf_0850	5.566e-80	290.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria,44WDR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_4178962_0	1123368.AUIS01000019_gene1206	6.125e-97	342.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,1RPG9@1236|Gammaproteobacteria,2NCE0@225057|Acidithiobacillales	225057|Acidithiobacillales	T	His Kinase A (phospho-acceptor) domain	-	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
LZS3_k127_4187464_0	1379698.RBG1_1C00001G1725	2.978e-276	900.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
LZS3_k127_4187464_4	511.JT27_19725	2.65e-50	195.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,3T39E@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA_2	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
LZS3_k127_4187464_1	1282876.BAOK01000001_gene2284	1.38e-184	600.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,4BPZN@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_4187464_3	76114.ebA3466	2.548e-78	293.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,2VHDT@28216|Betaproteobacteria,2KVYK@206389|Rhodocyclales	206389|Rhodocyclales	E	phosphoserine phosphatase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
LZS3_k127_4187464_2	1313172.YM304_27360	6.595e-160	514.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMUC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
LZS3_k127_4190240_0	479434.Sthe_2091	1.001e-55	218.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
LZS3_k127_4192322_2	404589.Anae109_4183	1.853e-32	136.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QS7@68525|delta/epsilon subdivisions,2X74U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
LZS3_k127_4192322_4	1242864.D187_001136	0.0007178	51.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpM	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding,ketoacyl-synt
LZS3_k127_4192322_1	1254432.SCE1572_12650	1.819e-57	221.0	COG1755@1|root,COG1755@2|Bacteria,1N00M@1224|Proteobacteria,42V8A@68525|delta/epsilon subdivisions,2WRUF@28221|Deltaproteobacteria,2YUY3@29|Myxococcales	28221|Deltaproteobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
LZS3_k127_4192322_0	1144275.COCOR_07209	6.213e-138	447.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42S7Y@68525|delta/epsilon subdivisions,2WNF3@28221|Deltaproteobacteria,2YZHC@29|Myxococcales	28221|Deltaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	2.3.1.233	ko:K16167,ko:K19580	-	-	R10965	RC00004	ko00000,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
LZS3_k127_4192322_3	1040986.ATYO01000009_gene2345	4.897e-16	83.0	COG3568@1|root,COG3568@2|Bacteria,1P2WU@1224|Proteobacteria,2U2FR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS3_k127_420466_6	644282.Deba_0294	0.000314	48.0	COG3027@1|root,COG3027@2|Bacteria,1Q3I5@1224|Proteobacteria,42XCY@68525|delta/epsilon subdivisions,2WSR7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Cell division protein ZapA	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
LZS3_k127_420466_2	1205680.CAKO01000029_gene5245	1.539e-179	575.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,2JQ6Q@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
LZS3_k127_420466_0	517418.Ctha_2166	0.0	1808.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1FDQP@1090|Chlorobi	1090|Chlorobi	C	glutamate synthase, alpha subunit domain protein	-	-	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
LZS3_k127_420466_5	1304888.ATWF01000001_gene2116	5.07e-27	126.0	COG1522@1|root,COG1522@2|Bacteria,2GFM8@200930|Deferribacteres	200930|Deferribacteres	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24
LZS3_k127_420466_4	1121342.AUCO01000019_gene1194	2.088e-41	171.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,36F9I@31979|Clostridiaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
LZS3_k127_420466_1	644966.Tmar_1638	4.354e-203	643.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WCWS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
LZS3_k127_420466_3	1410618.JNKI01000001_gene1269	3.6e-76	259.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4H1WP@909932|Negativicutes	909932|Negativicutes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
LZS3_k127_4205584_3	671143.DAMO_1981	2.156e-36	141.0	COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
LZS3_k127_4205584_1	671143.DAMO_1982	3.853e-68	241.0	COG1120@1|root,COG1120@2|Bacteria	2|Bacteria	HP	ATPase activity	hmuV	-	3.6.3.34	ko:K02013,ko:K09817	ko02010,map02010	M00240,M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14,3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
LZS3_k127_4205584_2	671143.DAMO_1983	1.044e-54	211.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
LZS3_k127_4205584_0	247634.GPB2148_2560	2.247e-110	373.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1S56F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_4205584_4	309807.SRU_1452	4.877e-19	100.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4218955_1	1125863.JAFN01000001_gene1045	1.254e-59	234.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	A	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
LZS3_k127_4218955_0	1125863.JAFN01000001_gene2828	2.7e-133	443.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,43AW1@68525|delta/epsilon subdivisions,2X6A7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_4218955_2	1346791.M529_13010	8.266e-19	88.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2U6NR@28211|Alphaproteobacteria,2K2XA@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
LZS3_k127_4238836_1	290397.Adeh_3956	2.496e-36	145.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4238836_0	589865.DaAHT2_2567	1.67e-56	203.0	COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,42VBZ@68525|delta/epsilon subdivisions,2WS0K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
LZS3_k127_4246044_2	2074.JNYD01000010_gene998	6.87e-76	269.0	COG1063@1|root,COG1063@2|Bacteria,2GNFX@201174|Actinobacteria,4E2BI@85010|Pseudonocardiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_4246044_1	1122939.ATUD01000007_gene2126	6.187e-85	308.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria,4CPZF@84995|Rubrobacteria	84995|Rubrobacteria	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS3_k127_4246044_4	1229172.JQFA01000004_gene1664	4.179e-09	70.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,1GHDU@1117|Cyanobacteria,1H7K6@1150|Oscillatoriales	1117|Cyanobacteria	Q	Endonuclease/Exonuclease/phosphatase family	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,HemolysinCabind,LTD
LZS3_k127_4246044_0	450851.PHZ_c1574	1.138e-123	415.0	COG0183@1|root,COG0183@2|Bacteria,1MVPC@1224|Proteobacteria,2VEVD@28211|Alphaproteobacteria,2KF3X@204458|Caulobacterales	204458|Caulobacterales	I	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
LZS3_k127_4246044_3	404589.Anae109_2428	1.559e-39	153.0	COG3945@1|root,COG3945@2|Bacteria,1NG3G@1224|Proteobacteria,42WHU@68525|delta/epsilon subdivisions,2WRK5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
LZS3_k127_4246044_5	1415780.JPOG01000001_gene3153	6.046e-05	46.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,1RX69@1236|Gammaproteobacteria,1XASM@135614|Xanthomonadales	135614|Xanthomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_4275199_0	1122603.ATVI01000008_gene2232	1.234e-80	296.0	COG0664@1|root,COG1033@1|root,COG0664@2|Bacteria,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1X3P5@135614|Xanthomonadales	135614|Xanthomonadales	T	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	-	-	-	-	-	-	-	-	-	MMPL,cNMP_binding
LZS3_k127_4275199_1	665571.STHERM_c14210	3.757e-21	104.0	COG3026@1|root,COG3026@2|Bacteria,2J61M@203691|Spirochaetes	203691|Spirochaetes	T	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
LZS3_k127_4277307_1	452637.Oter_2265	2.916e-28	134.0	COG3391@1|root,COG3391@2|Bacteria,46UA2@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3,NHL
LZS3_k127_4277307_2	112098.XP_008608261.1	3.351e-07	64.0	KOG1217@1|root,KOG1217@2759|Eukaryota	2759|Eukaryota	O	calcium ion binding	-	-	-	ko:K02599	ko01522,ko04320,ko04330,ko04658,ko04919,ko05020,ko05165,ko05200,ko05206,ko05224,map01522,map04320,map04330,map04658,map04919,map05020,map05165,map05200,map05206,map05224	M00682	-	-	ko00000,ko00001,ko00002	-	-	-	LCCL,NHL
LZS3_k127_4308773_3	1307759.JOMJ01000004_gene2979	2.477e-56	220.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2M7XX@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
LZS3_k127_4308773_2	883.DvMF_2674	2.86e-60	230.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2M80N@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
LZS3_k127_4308773_0	1232410.KI421421_gene3690	1.896e-94	319.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,43S6P@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS3_k127_4308773_1	292415.Tbd_0491	3.327e-84	295.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria	28216|Betaproteobacteria	O	serine protease	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
LZS3_k127_431620_2	644282.Deba_3091	1.973e-08	63.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	eight transmembrane protein EpsH	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
LZS3_k127_431620_0	1123073.KB899241_gene2212	1.897e-163	526.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,1RMM2@1236|Gammaproteobacteria,1X3QG@135614|Xanthomonadales	135614|Xanthomonadales	G	COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
LZS3_k127_431620_1	756067.MicvaDRAFT_2438	2.014e-27	130.0	COG0457@1|root,COG0457@2|Bacteria,1G9RM@1117|Cyanobacteria,1HF94@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
LZS3_k127_4331049_1	1333998.M2A_0424	8.636e-81	274.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,2TTDK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
LZS3_k127_4331049_0	1123368.AUIS01000033_gene1374	6.317e-156	507.0	COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,1RMEB@1236|Gammaproteobacteria,2NCM6@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)	-	-	-	ko:K03670	-	-	-	-	ko00000	-	-	-	MdoG
LZS3_k127_4331049_2	1397527.Q670_10125	7.163e-21	98.0	COG0454@1|root,COG0456@2|Bacteria,1N4JC@1224|Proteobacteria,1SDHV@1236|Gammaproteobacteria,1XMSM@135619|Oceanospirillales	135619|Oceanospirillales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_435339_0	357808.RoseRS_2422	3.134e-28	122.0	COG0500@1|root,COG2226@2|Bacteria,2GBT7@200795|Chloroflexi,375QW@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_435339_1	596152.DesU5LDRAFT_0890	3.812e-24	118.0	COG1807@1|root,COG1807@2|Bacteria,1NTFE@1224|Proteobacteria,42Z1W@68525|delta/epsilon subdivisions,2WTMJ@28221|Deltaproteobacteria,2M8VB@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_435671_0	1056820.KB900637_gene164	2.974e-296	942.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,2PNCX@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_5_12_2,Cytochrome_CBB3,GSDH,He_PIG,PA14
LZS3_k127_4373200_3	290397.Adeh_0640	1.551e-10	68.0	COG1396@1|root,COG1396@2|Bacteria,1QYFR@1224|Proteobacteria,43CBW@68525|delta/epsilon subdivisions,2X7MR@28221|Deltaproteobacteria,2Z2CU@29|Myxococcales	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
LZS3_k127_4373200_0	443144.GM21_1703	2.827e-154	523.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,43UG1@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	TIGRFAM phosphoenolpyruvate-protein phosphotransferase	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
LZS3_k127_4373200_1	396595.TK90_2100	1.643e-19	92.0	COG2026@1|root,COG2026@2|Bacteria,1N80B@1224|Proteobacteria,1SDK6@1236|Gammaproteobacteria,1WZ7U@135613|Chromatiales	135613|Chromatiales	DJ	PFAM plasmid	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
LZS3_k127_4373200_2	525897.Dbac_0824	2.717e-11	66.0	2E9PU@1|root,333W6@2|Bacteria,1N6VC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_3
LZS3_k127_4398486_2	1121920.AUAU01000002_gene2137	7.825e-18	92.0	COG5000@1|root,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS3_k127_4398486_0	477974.Daud_2039	5.025e-32	134.0	COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,24HXX@186801|Clostridia,262JG@186807|Peptococcaceae	186801|Clostridia	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_4398486_1	404589.Anae109_0165	1.878e-23	103.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2YUTZ@29|Myxococcales	28221|Deltaproteobacteria	M	Mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
LZS3_k127_4402120_0	240015.ACP_1964	2.749e-23	115.0	COG2208@1|root,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
LZS3_k127_4408747_0	1120936.KB907212_gene5172	1.324e-168	549.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4EGU0@85012|Streptosporangiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_4408747_1	314287.GB2207_03559	9.334e-33	137.0	COG2930@1|root,COG2930@2|Bacteria,1RCH3@1224|Proteobacteria,1S2SV@1236|Gammaproteobacteria,1J6Q3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Las17-binding protein actin regulator	VPA0371	-	-	-	-	-	-	-	-	-	-	-	Ysc84
LZS3_k127_441662_0	1382306.JNIM01000001_gene1613	1.751e-40	154.0	COG0247@1|root,COG0247@2|Bacteria,2G5V8@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
LZS3_k127_445052_1	1125863.JAFN01000001_gene746	7.732e-124	416.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Y98@68525|delta/epsilon subdivisions,2WTXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_445052_2	290397.Adeh_1668	1.214e-36	151.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS3_k127_445052_0	1125863.JAFN01000001_gene929	6.607e-172	576.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS3_k127_448699_1	404589.Anae109_4145	1.882e-75	285.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YUTC@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS3_k127_448699_0	404589.Anae109_4146	8.956e-80	282.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42TCH@68525|delta/epsilon subdivisions,2WPEI@28221|Deltaproteobacteria,2YU8R@29|Myxococcales	28221|Deltaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS3_k127_448699_9	398525.KB900701_gene1105	1.223e-24	112.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
LZS3_k127_448699_12	1122919.KB905567_gene2782	1.546e-06	54.0	COG0236@1|root,COG0236@2|Bacteria,1VPEA@1239|Firmicutes,4I065@91061|Bacilli,26ZFI@186822|Paenibacillaceae	91061|Bacilli	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS3_k127_448699_11	1000565.METUNv1_03930	3.301e-08	65.0	COG0110@1|root,COG0110@2|Bacteria,1RADJ@1224|Proteobacteria,2VQFY@28216|Betaproteobacteria,2KZ1K@206389|Rhodocyclales	206389|Rhodocyclales	S	maltose O-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_448699_2	106370.Francci3_1241	2.095e-67	236.0	COG0491@1|root,COG0491@2|Bacteria,2GNS6@201174|Actinobacteria	201174|Actinobacteria	P	PFAM Metallo-beta-lactamase superfamily	gloB	GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_448699_6	234267.Acid_1166	1.237e-63	228.0	COG2086@1|root,COG2086@2|Bacteria,3Y2PD@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
LZS3_k127_448699_5	1121920.AUAU01000023_gene2418	4.433e-64	242.0	COG2025@1|root,COG2025@2|Bacteria,3Y4SJ@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
LZS3_k127_448699_4	635013.TherJR_1731	3.047e-66	247.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,261EB@186807|Peptococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
LZS3_k127_448699_3	439235.Dalk_4932	3.87e-67	241.0	COG2378@1|root,COG2378@2|Bacteria,1P2ZE@1224|Proteobacteria,42QIS@68525|delta/epsilon subdivisions,2WMK0@28221|Deltaproteobacteria,2MKS9@213118|Desulfobacterales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
LZS3_k127_448699_7	1280944.HY17_04800	4.275e-47	190.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2U55H@28211|Alphaproteobacteria,43XPN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	COG0208 Ribonucleotide reductase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	AurF
LZS3_k127_448699_10	1131814.JAFO01000001_gene3505	3.017e-16	88.0	COG1309@1|root,COG1309@2|Bacteria,1R5AI@1224|Proteobacteria,2U5HX@28211|Alphaproteobacteria,3EZM3@335928|Xanthobacteraceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
LZS3_k127_448699_8	880072.Desac_1624	4.905e-37	147.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WR3G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_4490452_0	266117.Rxyl_0960	3.452e-148	482.0	COG0722@1|root,COG0722@2|Bacteria,2GMVF@201174|Actinobacteria,4CSEZ@84995|Rubrobacteria	84995|Rubrobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS3_k127_4490452_1	29581.BW37_01460	3.16e-53	209.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,476K9@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PAS fold	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_9
LZS3_k127_4496250_0	439235.Dalk_2989	1.663e-120	401.0	COG3119@1|root,COG3119@2|Bacteria,1PFYE@1224|Proteobacteria,43A2J@68525|delta/epsilon subdivisions,2WQC7@28221|Deltaproteobacteria,2MNWS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_4496250_2	1206732.BAGD01000091_gene4000	4.659e-37	154.0	COG0500@1|root,COG2226@2|Bacteria,2HFGE@201174|Actinobacteria,4FV65@85025|Nocardiaceae	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_4496250_1	391625.PPSIR1_01774	6.878e-71	244.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42QKW@68525|delta/epsilon subdivisions,2WKH1@28221|Deltaproteobacteria,2YWTQ@29|Myxococcales	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_4505090_1	247639.MGP2080_01966	7.084e-163	526.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,1SZ21@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
LZS3_k127_4505090_0	1192034.CAP_6838	2.367e-183	593.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42Z9H@68525|delta/epsilon subdivisions,2WUIK@28221|Deltaproteobacteria,2YUAX@29|Myxococcales	28221|Deltaproteobacteria	K	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
LZS3_k127_4510972_0	391165.GbCGDNIH1_2401	6.879e-172	550.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TRFJ@28211|Alphaproteobacteria,2JRB5@204441|Rhodospirillales	204441|Rhodospirillales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS3_k127_4510972_1	266265.Bxe_B0386	1.797e-18	94.0	COG3394@1|root,COG3394@2|Bacteria,1MX3P@1224|Proteobacteria,2VSK0@28216|Betaproteobacteria,1K15V@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM YdjC family protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
LZS3_k127_4511773_0	15368.BRADI1G34190.2	7.814e-56	221.0	COG0661@1|root,KOG1235@2759|Eukaryota,37N5M@33090|Viridiplantae,3GF6V@35493|Streptophyta,3KKZJ@4447|Liliopsida,3I4GY@38820|Poales	35493|Streptophyta	S	Beta-lactamase	-	-	-	ko:K08869	-	-	-	-	ko00000,ko01001	-	-	-	ABC1,Beta-lactamase,WaaY
LZS3_k127_4511773_1	1333998.M2A_2494	3.034e-54	204.0	2EXDM@1|root,33QQ7@2|Bacteria,1NTQ6@1224|Proteobacteria,2UQVJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4511773_2	345341.KUTG_08007	1.132e-08	58.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4E0P3@85010|Pseudonocardiales	201174|Actinobacteria	C	ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes	calB	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_4518213_0	869210.Marky_1772	0.0004408	52.0	COG2304@1|root,COG2304@2|Bacteria,1WJG3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA_2
LZS3_k127_4521003_0	88036.EFJ33292	2.791e-126	417.0	COG0626@1|root,KOG0053@2759|Eukaryota,37K09@33090|Viridiplantae,3G79I@35493|Streptophyta	35493|Streptophyta	E	Cystathionine gamma-synthase	-	GO:0000096,GO:0000097,GO:0001887,GO:0003674,GO:0003824,GO:0003962,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
LZS3_k127_4521190_2	525897.Dbac_2229	2.198e-24	115.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria,2M919@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
LZS3_k127_4521190_0	1313172.YM304_06500	8.833e-91	307.0	COG2141@1|root,COG2141@2|Bacteria,2H89R@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_4521190_1	749414.SBI_02500	1.698e-79	270.0	COG0693@1|root,COG0693@2|Bacteria,2H6FV@201174|Actinobacteria	201174|Actinobacteria	S	ThiJ PfpI	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
LZS3_k127_4521190_3	1137269.AZWL01000003_gene1568	7.272e-18	87.0	COG1167@1|root,COG1167@2|Bacteria,2GM6I@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	ptsJ	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
LZS3_k127_4524236_0	1254432.SCE1572_51875	1.734e-280	879.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2X7DH@28221|Deltaproteobacteria,2YUKN@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
LZS3_k127_4524236_2	1238182.C882_3050	3.61e-24	113.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria,2JPKA@204441|Rhodospirillales	204441|Rhodospirillales	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
LZS3_k127_4524236_1	402881.Plav_1983	1.514e-137	451.0	COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,2TRU9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
LZS3_k127_4524907_0	573370.DMR_44650	1.546e-169	551.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2M832@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS3_k127_4524907_1	401526.TcarDRAFT_0073	1.448e-05	49.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H2UN@909932|Negativicutes	909932|Negativicutes	S	ABC transporter, ATP-binding protein	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS3_k127_4552262_1	469383.Cwoe_3478	1.418e-58	212.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_4552262_0	1380390.JIAT01000010_gene4575	2.121e-110	384.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_4552262_2	472759.Nhal_2790	1.376e-05	51.0	2E41E@1|root,32YY1@2|Bacteria,1NGB3@1224|Proteobacteria,1SDTK@1236|Gammaproteobacteria,1X1PQ@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398
LZS3_k127_4560293_0	745411.B3C1_03705	4.447e-137	456.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RQH7@1236|Gammaproteobacteria,1J59S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_4560293_1	1283300.ATXB01000002_gene2858	1.815e-07	60.0	COG4648@1|root,COG4648@2|Bacteria,1P3DU@1224|Proteobacteria,1SR7N@1236|Gammaproteobacteria,1XFTB@135618|Methylococcales	135618|Methylococcales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4570784_1	1280689.AUJC01000001_gene2531	2.239e-72	251.0	COG0451@1|root,COG0451@2|Bacteria,1VP6I@1239|Firmicutes,251A8@186801|Clostridia,36UJ5@31979|Clostridiaceae	186801|Clostridia	M	NAD-dependent epimerase dehydratase	capI	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS3_k127_4570784_0	370438.PTH_1095	1.25e-101	351.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,261N7@186807|Peptococcaceae	186801|Clostridia	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.20,5.1.3.7	ko:K01784,ko:K02473,ko:K03274	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	M00064,M00361,M00362,M00632	R00291,R00418,R02984,R05176	RC00289,RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,GDP_Man_Dehyd
LZS3_k127_4570784_2	591019.Shell_0881	2.028e-09	63.0	COG0451@1|root,arCOG01369@2157|Archaea,2XPYT@28889|Crenarchaeota	28889|Crenarchaeota	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS3_k127_4601050_0	1382356.JQMP01000001_gene1159	2.969e-196	629.0	COG0318@1|root,COG0318@2|Bacteria,2G5NE@200795|Chloroflexi,27YYW@189775|Thermomicrobia	189775|Thermomicrobia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_4601050_1	1163617.SCD_n02093	4.836e-102	339.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
LZS3_k127_4601050_2	861299.J421_0923	5.085e-06	59.0	COG1234@1|root,COG1234@2|Bacteria,1ZUWE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS3_k127_462036_4	1123024.AUII01000023_gene262	0.0002962	49.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
LZS3_k127_462036_3	1267533.KB906738_gene2151	1.515e-30	129.0	COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria,2JJ7J@204432|Acidobacteriia	204432|Acidobacteriia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
LZS3_k127_462036_2	1128421.JAGA01000002_gene275	2.702e-37	144.0	COG0251@1|root,COG0251@2|Bacteria,2NPSA@2323|unclassified Bacteria	2|Bacteria	J	Endoribonuclease L-PSP	rutC	GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.99.10	ko:K09021,ko:K09022	ko00240,ko01100,map00240,map01100	-	R09982,R11098,R11099	RC02768,RC03275,RC03354	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
LZS3_k127_462036_1	1089551.KE386572_gene1863	3.887e-47	175.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,4BQAH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
LZS3_k127_462036_0	1042377.AFPJ01000037_gene2939	2.79e-51	199.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1SZ0N@1236|Gammaproteobacteria,46CIY@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
LZS3_k127_4620671_0	469383.Cwoe_0601	4.906e-145	477.0	COG2114@1|root,COG2909@1|root,COG3899@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria	201174|Actinobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc
LZS3_k127_462326_3	1454010.JEOE01000029_gene3027	3.123e-26	113.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4F1DC@85016|Cellulomonadaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS3_k127_462326_0	246197.MXAN_5885	1.621e-55	209.0	COG3917@1|root,COG3917@2|Bacteria,1RA6I@1224|Proteobacteria,43DNK@68525|delta/epsilon subdivisions,2X6M0@28221|Deltaproteobacteria,2Z3BP@29|Myxococcales	28221|Deltaproteobacteria	G	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
LZS3_k127_462326_2	471852.Tcur_2668	3.072e-47	184.0	COG5485@1|root,COG5485@2|Bacteria,2GMYI@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
LZS3_k127_462326_1	204669.Acid345_2346	5.599e-52	193.0	COG1560@1|root,COG1560@2|Bacteria,3Y2RW@57723|Acidobacteria,2JIMS@204432|Acidobacteriia	204432|Acidobacteriia	M	lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
LZS3_k127_462544_0	1048339.KB913029_gene2594	2.756e-106	356.0	COG1168@1|root,COG1168@2|Bacteria,2GJFQ@201174|Actinobacteria,4ESK6@85013|Frankiales	201174|Actinobacteria	E	PFAM Aminotransferase class I and II	aecD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	4.4.1.8	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_462544_1	1356852.N008_00185	2.653e-45	190.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	peaD	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Rhomboid
LZS3_k127_462605_0	1123256.KB907925_gene1298	1.866e-129	437.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1X36Z@135614|Xanthomonadales	135614|Xanthomonadales	E	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS3_k127_462605_1	443143.GM18_1204	7.469e-55	204.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42PGP@68525|delta/epsilon subdivisions,2WMGP@28221|Deltaproteobacteria,43TG9@69541|Desulfuromonadales	28221|Deltaproteobacteria	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,Methyltransf_11
LZS3_k127_4655600_0	195105.CN97_17610	0.0004664	53.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2TUPX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
LZS3_k127_4661593_4	760192.Halhy_3973	2.336e-06	59.0	COG0760@1|root,COG0760@2|Bacteria,4NEW0@976|Bacteroidetes,1IQB4@117747|Sphingobacteriia	976|Bacteroidetes	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
LZS3_k127_4661593_0	264732.Moth_0255	0.0	1042.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS3_k127_4661593_3	357808.RoseRS_1100	6.33e-14	84.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
LZS3_k127_4661593_1	1123242.JH636434_gene4961	9.854e-63	235.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
LZS3_k127_4661593_2	583355.Caka_2620	9.386e-25	117.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
LZS3_k127_4669338_0	357808.RoseRS_3083	3.719e-124	426.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS3_k127_4669338_1	497964.CfE428DRAFT_0933	7.791e-99	332.0	COG0318@1|root,COG0318@2|Bacteria,46T54@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_4675359_0	313624.NSP_46940	1.896e-162	523.0	COG0671@1|root,COG0671@2|Bacteria,1G24P@1117|Cyanobacteria,1HK6H@1161|Nostocales	1117|Cyanobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4675359_1	1379698.RBG1_1C00001G0624	7.421e-30	126.0	COG0842@1|root,COG0842@2|Bacteria,2NPA6@2323|unclassified Bacteria	2|Bacteria	V	ABC-type multidrug transport system, permease component	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS3_k127_4676234_1	1396418.BATQ01000120_gene3056	4.362e-130	421.0	COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia,2ITM1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
LZS3_k127_4676234_2	335543.Sfum_1456	1.51e-111	395.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WK44@28221|Deltaproteobacteria,2MQ56@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	MFS_1,OEP
LZS3_k127_4676234_0	335543.Sfum_1457	0.0	1270.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MR4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Protein export membrane protein	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
LZS3_k127_4676234_3	335543.Sfum_1458	1.158e-107	379.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MR8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS3_k127_4676234_4	28229.ND2E_3822	2.108e-35	148.0	COG2207@1|root,COG2207@2|Bacteria,1Q3UX@1224|Proteobacteria,1RS88@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
LZS3_k127_4676234_5	634497.HAH_4380	0.0005081	44.0	COG3174@1|root,arCOG04203@2157|Archaea,2XT0W@28890|Euryarchaeota,23UFT@183963|Halobacteria	183963|Halobacteria	P	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
LZS3_k127_471470_2	867903.ThesuDRAFT_00620	2.514e-41	158.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WD56@538999|Clostridiales incertae sedis	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
LZS3_k127_471470_3	521393.JH806632_gene532	4.363e-35	149.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4D5SI@85005|Actinomycetales	201174|Actinobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	GO:0003674,GO:0003824,GO:0004068,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
LZS3_k127_471470_1	1278073.MYSTI_02351	6.901e-86	295.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2WJ19@28221|Deltaproteobacteria,2YUVT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
LZS3_k127_471470_0	477974.Daud_0100	9.759e-87	299.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
LZS3_k127_4740026_0	365046.Rta_22760	3.057e-72	265.0	COG1541@1|root,COG1541@2|Bacteria,1QZDY@1224|Proteobacteria,2VIX3@28216|Betaproteobacteria,4ABQT@80864|Comamonadaceae	28216|Betaproteobacteria	H	Acyl-protein synthetase, LuxE	-	-	6.2.1.19	ko:K06046	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	LuxE
LZS3_k127_4740026_1	1123070.KB899254_gene1284	9.327e-55	199.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS3_k127_4741477_1	1173028.ANKO01000044_gene677	1.68e-05	51.0	COG2027@1|root,COG2027@2|Bacteria,1G06E@1117|Cyanobacteria,1H79I@1150|Oscillatoriales	1117|Cyanobacteria	M	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
LZS3_k127_4741477_0	305700.B447_07137	1.666e-229	720.0	COG2211@1|root,COG2211@2|Bacteria,1MWSH@1224|Proteobacteria,2VJEQ@28216|Betaproteobacteria,2KUQ3@206389|Rhodocyclales	206389|Rhodocyclales	G	BT1 family	-	-	-	-	-	-	-	-	-	-	-	-	BT1
LZS3_k127_4746119_1	1089553.Tph_c06940	7.077e-162	521.0	COG4303@1|root,COG4303@2|Bacteria,1TP15@1239|Firmicutes,248P5@186801|Clostridia	186801|Clostridia	E	PFAM Ethanolamine ammonia lyase large subunit	eutB	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
LZS3_k127_4746119_4	684949.ATTJ01000001_gene2880	2.751e-22	109.0	2DC00@1|root,2ZC4V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4746119_2	1121920.AUAU01000017_gene1220	3.784e-70	247.0	COG5587@1|root,COG5587@2|Bacteria,3Y4D4@57723|Acidobacteria	57723|Acidobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
LZS3_k127_4746119_3	1254432.SCE1572_50495	1.226e-54	198.0	COG5628@1|root,COG5628@2|Bacteria,1PEIJ@1224|Proteobacteria,432V3@68525|delta/epsilon subdivisions,2WXD7@28221|Deltaproteobacteria,2Z02A@29|Myxococcales	28221|Deltaproteobacteria	S	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_4746119_5	903818.KI912269_gene535	3.645e-10	69.0	COG5460@1|root,COG5460@2|Bacteria,3Y57J@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
LZS3_k127_4746119_0	1242864.D187_006651	6.181e-177	576.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2YV8R@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
LZS3_k127_4746825_0	1144275.COCOR_07906	1.616e-19	94.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
LZS3_k127_4746825_1	215803.DB30_3401	6.237e-12	78.0	COG4191@1|root,COG4191@2|Bacteria,1QTMQ@1224|Proteobacteria,437ZP@68525|delta/epsilon subdivisions,2X9TE@28221|Deltaproteobacteria,2YUZV@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
LZS3_k127_4747509_0	1298867.AUES01000015_gene3847	1.952e-50	187.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,2TSTP@28211|Alphaproteobacteria,3JU6V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_4747509_2	225849.swp_3620	5.62e-06	55.0	2FCZD@1|root,33QTZ@2|Bacteria,1NU91@1224|Proteobacteria,1SMIR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4747509_1	246197.MXAN_2256	1.146e-06	56.0	COG0526@1|root,COG2849@1|root,COG0526@2|Bacteria,COG2849@2|Bacteria,1PP8W@1224|Proteobacteria,4392Y@68525|delta/epsilon subdivisions,2X48S@28221|Deltaproteobacteria,2YYI3@29|Myxococcales	28221|Deltaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
LZS3_k127_4757034_0	937777.Deipe_1317	2.266e-66	235.0	COG2059@1|root,COG2059@2|Bacteria,1WKSK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	COG2059 Chromate transport protein ChrA	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
LZS3_k127_4757034_1	269799.Gmet_1056	6.392e-25	113.0	COG4914@1|root,COG4914@2|Bacteria,1N49U@1224|Proteobacteria,42WH5@68525|delta/epsilon subdivisions,2WRDY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
LZS3_k127_4764125_2	697281.Mahau_1428	1.685e-56	214.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,42FNE@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM multi antimicrobial extrusion protein MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
LZS3_k127_4764125_1	1313172.YM304_41020	1.228e-73	258.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4CNUE@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_4764125_0	1121439.dsat_0880	3.799e-276	874.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2M92I@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	ATP-dependent Clp protease ATP-binding subunit ClpA	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS3_k127_4764125_3	1232410.KI421421_gene3814	6.021e-26	111.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,43SN3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ATP-dependent Clp protease adaptor protein ClpS	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
LZS3_k127_4770894_3	999541.bgla_2g26870	6.783e-15	81.0	COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,2VQPY@28216|Betaproteobacteria,1K41Q@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
LZS3_k127_4770894_2	247490.KSU1_C1420	3.352e-20	106.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	ydiY	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF3078,DUF481
LZS3_k127_4770894_1	1029823.AFIE01000001_gene2055	2.456e-80	301.0	COG3239@1|root,COG3239@2|Bacteria,1N2FA@1224|Proteobacteria,1SC1D@1236|Gammaproteobacteria,3NIQR@468|Moraxellaceae	1236|Gammaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
LZS3_k127_4770894_0	236097.ADG881_2831	9.277e-241	764.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,1XR7R@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_4810825_0	266117.Rxyl_2540	4.568e-121	403.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria	84995|Rubrobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
LZS3_k127_4810825_1	1123399.AQVE01000006_gene3450	5.203e-18	89.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,1RN7Z@1236|Gammaproteobacteria,461KC@72273|Thiotrichales	72273|Thiotrichales	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
LZS3_k127_48263_1	1499967.BAYZ01000048_gene2700	1.975e-74	267.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2,MFS_3
LZS3_k127_48263_0	1068980.ARVW01000001_gene7819	9.247e-117	397.0	COG2141@1|root,COG2141@2|Bacteria,2GNQ1@201174|Actinobacteria,4E1GS@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_48263_2	420324.KI911961_gene1644	2.149e-33	135.0	COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria,2U3M0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4242,Guanylate_cyc
LZS3_k127_4826496_1	96561.Dole_1367	6.44e-62	233.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MHTH@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
LZS3_k127_4826496_0	880072.Desac_2046	3.158e-86	296.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria,2MQRC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
LZS3_k127_4826496_2	1232410.KI421421_gene3474	1.297e-06	55.0	COG3215@1|root,COG3215@2|Bacteria,1NW7J@1224|Proteobacteria,43C0W@68525|delta/epsilon subdivisions,2WVFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
LZS3_k127_4829109_2	1121448.DGI_0655	1.984e-25	113.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS3_k127_4829109_0	479434.Sthe_0748	1.622e-53	202.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
LZS3_k127_4829109_1	1122921.KB898185_gene3953	8.908e-29	119.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,4HH5V@91061|Bacilli,26VDH@186822|Paenibacillaceae	91061|Bacilli	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
LZS3_k127_4829109_3	1499967.BAYZ01000088_gene5132	1.016e-11	66.0	COG0521@1|root,COG0521@2|Bacteria,2NR7Z@2323|unclassified Bacteria	2|Bacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
LZS3_k127_484928_1	1234364.AMSF01000005_gene803	2.413e-61	224.0	COG1524@1|root,COG1524@2|Bacteria,1N5SF@1224|Proteobacteria,1RS7W@1236|Gammaproteobacteria,1X350@135614|Xanthomonadales	135614|Xanthomonadales	S	proteins of the AP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_484928_3	1305732.JAGG01000001_gene2114	9.869e-49	180.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria,4FSI4@85023|Microbacteriaceae	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
LZS3_k127_484928_0	7994.ENSAMXP00000019514	3.25e-191	612.0	KOG1406@1|root,KOG4170@1|root,KOG1406@2759|Eukaryota,KOG4170@2759|Eukaryota,38CKQ@33154|Opisthokonta,3BDZX@33208|Metazoa,3CUCP@33213|Bilateria,483XX@7711|Chordata,48ZBY@7742|Vertebrata,49WEN@7898|Actinopterygii	33208|Metazoa	I	Belongs to the thiolase family	SCP2	GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911	2.3.1.176	ko:K08764	ko00120,ko01100,ko03320,ko04146,map00120,map01100,map03320,map04146	M00104	R03719,R04811	RC00004,RC00405,RC02725	ko00000,ko00001,ko00002,ko01000	-	-	-	SCP2,Thiolase_C,Thiolase_N
LZS3_k127_484928_4	378806.STAUR_1007	7.215e-31	134.0	COG0546@1|root,COG0546@2|Bacteria,1Q3MM@1224|Proteobacteria,439F0@68525|delta/epsilon subdivisions,2X4Q9@28221|Deltaproteobacteria,2YZDY@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS3_k127_484928_2	1149133.ppKF707_2584	4.359e-51	185.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,1RN1W@1236|Gammaproteobacteria,1YD2G@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
LZS3_k127_4880804_2	675635.Psed_5472	4.772e-36	153.0	COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EF7B@85010|Pseudonocardiales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
LZS3_k127_4880804_0	1313172.YM304_02290	7.651e-101	346.0	COG0654@1|root,COG0654@2|Bacteria,2I901@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,NAD_binding_8,Trp_halogenase
LZS3_k127_4880804_1	1168065.DOK_02681	6.893e-68	243.0	COG1262@1|root,COG3509@1|root,COG1262@2|Bacteria,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	CE1	-	Abhydrolase_2,Esterase_phd,FGE-sulfatase,VPEP
LZS3_k127_4913330_0	1123023.JIAI01000019_gene2233	2.041e-198	630.0	COG0526@1|root,COG0526@2|Bacteria,2IET9@201174|Actinobacteria,4EASN@85010|Pseudonocardiales	201174|Actinobacteria	CO	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4913330_1	526225.Gobs_2419	3.221e-30	124.0	2E6FA@1|root,3312Q@2|Bacteria,2GUWJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4913330_2	1323663.AROI01000026_gene1885	3.099e-16	80.0	2DS3D@1|root,33EC4@2|Bacteria,1P2RI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4913330_3	1041146.ATZB01000034_gene597	4.262e-11	71.0	COG3678@1|root,COG3678@2|Bacteria,1N0SB@1224|Proteobacteria,2UDWY@28211|Alphaproteobacteria,4BAUZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	NPTU	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
LZS3_k127_4913330_4	1485544.JQKP01000001_gene1265	0.000601	43.0	COG0745@1|root,COG0745@2|Bacteria,1PFQS@1224|Proteobacteria,2W982@28216|Betaproteobacteria,44WHJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483,ko:K07662	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_4916194_1	290397.Adeh_0260	4.28e-05	51.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_16
LZS3_k127_4916194_0	1120985.AUMI01000011_gene577	5.278e-87	308.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H355@909932|Negativicutes	909932|Negativicutes	P	Transporter DASS family	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS3_k127_4934509_0	1192034.CAP_5082	1.015e-05	59.0	COG3055@1|root,COG5184@1|root,COG3055@2|Bacteria,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2Z3A7@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
LZS3_k127_4934509_1	338966.Ppro_2037	0.0008313	49.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS3_k127_4988683_3	290397.Adeh_1902	2.068e-17	94.0	2CDR8@1|root,32ZSF@2|Bacteria,1NCBG@1224|Proteobacteria,42V4S@68525|delta/epsilon subdivisions,2WSDP@28221|Deltaproteobacteria,2YVN6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4988683_2	502025.Hoch_3643	1.504e-21	109.0	COG0455@1|root,COG0484@1|root,COG1426@1|root,COG0455@2|Bacteria,COG0484@2|Bacteria,COG1426@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2YUZU@29|Myxococcales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
LZS3_k127_4988683_1	589865.DaAHT2_2396	8.609e-63	228.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2MKRR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
LZS3_k127_4988683_0	290397.Adeh_1905	3.964e-77	265.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,437B2@68525|delta/epsilon subdivisions,2X2FR@28221|Deltaproteobacteria,2Z0QW@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
LZS3_k127_4988683_4	266117.Rxyl_1983	5.25e-06	50.0	COG1921@1|root,COG1921@2|Bacteria,2HFGK@201174|Actinobacteria,4CPAR@84995|Rubrobacteria	84995|Rubrobacteria	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
LZS3_k127_4989812_2	1278073.MYSTI_00215	1.394e-34	153.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	ybaP	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
LZS3_k127_4989812_1	522306.CAP2UW1_2502	9.844e-93	329.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2VJ1C@28216|Betaproteobacteria,1KR7Q@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_4989812_5	391625.PPSIR1_09036	4.91e-24	104.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2Z1V1@29|Myxococcales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
LZS3_k127_4989812_4	391625.PPSIR1_09041	2.057e-24	106.0	COG0254@1|root,COG0254@2|Bacteria	2|Bacteria	J	rRNA binding	rpmE2	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
LZS3_k127_4989812_6	1380391.JIAS01000018_gene846	8.663e-23	104.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,2JT8U@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
LZS3_k127_4989812_0	383372.Rcas_2554	6.913e-135	445.0	COG3669@1|root,COG3669@2|Bacteria,2G801@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 29 (alpha-L-fucosidase)	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
LZS3_k127_4989812_3	1394178.AWOO02000051_gene6020	3.992e-31	126.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,4EG5H@85012|Streptosporangiales	201174|Actinobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
LZS3_k127_4999072_1	479434.Sthe_3486	1.269e-74	283.0	COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia	189775|Thermomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4999072_0	479434.Sthe_3485	3.784e-172	552.0	COG1239@1|root,COG1239@2|Bacteria,2GB7G@200795|Chloroflexi,27XRK@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
LZS3_k127_4999072_3	197221.22296037	6.527e-37	150.0	COG4783@1|root,COG4783@2|Bacteria,1G1TE@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_4999072_2	648996.Theam_0110	1.338e-64	232.0	COG2074@1|root,COG2074@2|Bacteria,2G4F4@200783|Aquificae	200783|Aquificae	G	ATP cone domain	-	-	-	ko:K05715	-	-	R02664	RC00002,RC00017	ko00000,ko01000	-	-	-	ATP-cone
LZS3_k127_5003968_1	867903.ThesuDRAFT_02285	2.697e-35	150.0	COG3852@1|root,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,24IAZ@186801|Clostridia,3WD9X@538999|Clostridiales incertae sedis	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K07710	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9
LZS3_k127_5003968_0	404589.Anae109_1798	7.571e-113	392.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_5018286_1	66429.JOFL01000024_gene5953	6.936e-20	103.0	COG1254@1|root,COG1254@2|Bacteria	2|Bacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
LZS3_k127_5018286_0	1907.SGLAU_02090	1.986e-127	424.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria	201174|Actinobacteria	M	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_5024396_2	290397.Adeh_0078	3.173e-40	157.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5024396_4	319003.Bra1253DRAFT_01363	4.961e-05	52.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2U1EH@28211|Alphaproteobacteria,3K65K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_5024396_0	290397.Adeh_2510	4.619e-141	462.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,42PEB@68525|delta/epsilon subdivisions,2WM0Y@28221|Deltaproteobacteria,2Z349@29|Myxococcales	28221|Deltaproteobacteria	G	DeoC/LacD family aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
LZS3_k127_5024396_1	1232410.KI421421_gene3567	3.078e-65	230.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,42RI1@68525|delta/epsilon subdivisions,2WNBG@28221|Deltaproteobacteria,43UG5@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
LZS3_k127_5024396_3	404589.Anae109_4245	1.718e-17	85.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2X1W0@28221|Deltaproteobacteria,2YUZR@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_5024930_1	713587.THITH_17135	3.405e-73	257.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales	135613|Chromatiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS3_k127_5024930_3	671143.DAMO_1529	7.151e-12	79.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_5024930_2	313606.M23134_02270	3.284e-16	87.0	COG1309@1|root,COG1309@2|Bacteria,4NTB4@976|Bacteroidetes,47RD7@768503|Cytophagia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
LZS3_k127_5024930_0	99598.Cal7507_0165	2.589e-131	426.0	COG0031@1|root,COG0031@2|Bacteria,1G1AB@1117|Cyanobacteria,1HIG6@1161|Nostocales	1117|Cyanobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_5024930_4	1123253.AUBD01000008_gene339	2.17e-06	51.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,1RPRF@1236|Gammaproteobacteria,1X371@135614|Xanthomonadales	135614|Xanthomonadales	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
LZS3_k127_5026939_2	1231190.NA8A_24034	3.616e-10	73.0	COG4625@1|root,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,43IXV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	TIGRFAM outer membrane autotransporter barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR
LZS3_k127_5026939_0	886293.Sinac_5925	6.019e-111	380.0	COG0621@1|root,COG0621@2|Bacteria,2IWTE@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
LZS3_k127_5026939_1	1144275.COCOR_04461	2.885e-70	244.0	COG0346@1|root,COG0346@2|Bacteria,1RA9H@1224|Proteobacteria,439N8@68525|delta/epsilon subdivisions,2X4ZH@28221|Deltaproteobacteria,2YZW4@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase_4
LZS3_k127_503496_0	391165.GbCGDNIH1_0909	3.497e-100	347.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria,2JQS2@204441|Rhodospirillales	204441|Rhodospirillales	C	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate	cysI	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
LZS3_k127_5038346_1	443598.AUFA01000014_gene6948	1.681e-20	106.0	COG3753@1|root,COG3753@2|Bacteria,1N7FF@1224|Proteobacteria,2UI50@28211|Alphaproteobacteria,3JQQU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
LZS3_k127_5038346_0	483219.LILAB_20575	2.555e-40	163.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
LZS3_k127_5039566_2	1300345.LF41_282	5.602e-43	165.0	COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,1SEDW@1236|Gammaproteobacteria,1X95U@135614|Xanthomonadales	135614|Xanthomonadales	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
LZS3_k127_5039566_0	1286632.P278_31310	5.402e-196	631.0	28HMZ@1|root,2Z7WD@2|Bacteria,4P095@976|Bacteroidetes	2|Bacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
LZS3_k127_5039566_1	1380347.JNII01000005_gene3108	4.474e-46	173.0	COG1917@1|root,COG2114@1|root,COG1917@2|Bacteria,COG2114@2|Bacteria,2IASU@201174|Actinobacteria	201174|Actinobacteria	IT	Pfam Adenylate and Guanylate cyclase catalytic domain	lipJ	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc
LZS3_k127_5061931_1	1380393.JHVP01000002_gene1796	7.155e-27	119.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria,4EV9G@85013|Frankiales	201174|Actinobacteria	S	Putative serine esterase (DUF676)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,DUF676,PGAP1
LZS3_k127_5061931_0	493475.GARC_4235	1.6e-63	240.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
LZS3_k127_5073479_1	557599.MKAN_22810	4.459e-17	90.0	COG1848@1|root,COG1848@2|Bacteria,2IK8U@201174|Actinobacteria,2396G@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
LZS3_k127_5073479_0	710696.Intca_0703	1.974e-138	452.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria,4FEY3@85021|Intrasporangiaceae	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS3_k127_5085928_0	768671.ThimaDRAFT_3477	1.943e-133	438.0	COG1232@1|root,COG1232@2|Bacteria,1QX3T@1224|Proteobacteria,1T36E@1236|Gammaproteobacteria,1WYQD@135613|Chromatiales	135613|Chromatiales	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS3_k127_5085928_1	584708.Apau_0250	2.425e-125	442.0	COG5427@1|root,COG5427@2|Bacteria,3TBW1@508458|Synergistetes	508458|Synergistetes	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
LZS3_k127_5085928_2	926550.CLDAP_04870	5.775e-86	312.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_5155_1	330084.JNYZ01000013_gene5881	9.432e-99	329.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4E2Y1@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_5155_0	330214.NIDE3178	6.155e-168	542.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
LZS3_k127_5165122_1	502025.Hoch_6104	1.807e-98	336.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,43F2R@68525|delta/epsilon subdivisions,2X35T@28221|Deltaproteobacteria,2YUDS@29|Myxococcales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
LZS3_k127_5165122_2	1229780.BN381_100200	3.604e-70	261.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria,3UXBY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
LZS3_k127_5165122_3	391625.PPSIR1_28283	1.095e-67	245.0	COG0204@1|root,COG0204@2|Bacteria,1RF5A@1224|Proteobacteria,4300N@68525|delta/epsilon subdivisions,2WVIK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS3_k127_5165122_0	247634.GPB2148_2386	5.279e-108	358.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,1RN4Z@1236|Gammaproteobacteria,1J7IT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	3.1.4.54	ko:K13985	ko04723,map04723	-	-	-	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
LZS3_k127_5167635_1	1175306.GWL_30730	2.173e-48	194.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2VHP0@28216|Betaproteobacteria,4735E@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
LZS3_k127_5167635_0	1118235.CAJH01000046_gene2948	8.44e-49	184.0	COG0204@1|root,COG0204@2|Bacteria,1RDN7@1224|Proteobacteria,1S4Z5@1236|Gammaproteobacteria,1X4GD@135614|Xanthomonadales	135614|Xanthomonadales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS3_k127_517395_2	1333998.M2A_1299	7.581e-06	49.0	2EGAZ@1|root,33A2U@2|Bacteria,1NMCB@1224|Proteobacteria,2UMCZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_517395_1	946362.XP_004996893.1	2.798e-18	98.0	COG2335@1|root,KOG1225@1|root,KOG1225@2759|Eukaryota,KOG1437@2759|Eukaryota	2759|Eukaryota	M	regulation of chemokine (C-C motif) ligand 2 secretion	-	-	-	ko:K01691,ko:K19519	ko04310,map04310	-	-	-	ko00000,ko00001,ko04516	-	-	-	Cadherin,EGF_2,EGF_3,F5_F8_type_C,Fasciclin,TIG,WIF,Xlink
LZS3_k127_517395_0	1282876.BAOK01000002_gene502	2.322e-124	411.0	COG0208@1|root,COG0208@2|Bacteria,1R4T3@1224|Proteobacteria,2U55H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
LZS3_k127_521707_12	227377.CBU_1820	3.397e-06	56.0	2BHMV@1|root,32BQM@2|Bacteria,1N9I1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_521707_7	227377.CBU_1821	7.509e-28	119.0	COG4453@1|root,COG4453@2|Bacteria	2|Bacteria	K	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
LZS3_k127_521707_13	118173.KB235910_gene4948	1.814e-05	57.0	2CX21@1|root,32T0Y@2|Bacteria,1G8F6@1117|Cyanobacteria,1HFXN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_521707_4	1173020.Cha6605_2546	2.178e-51	187.0	28KW4@1|root,2ZACH@2|Bacteria,1G2SE@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_521707_1	1000565.METUNv1_02811	1.257e-74	275.0	COG4585@1|root,COG4585@2|Bacteria,1R1TC@1224|Proteobacteria,2VHUA@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3
LZS3_k127_521707_5	381666.H16_B2299	5.417e-50	186.0	COG2197@1|root,COG2197@2|Bacteria,1R2TM@1224|Proteobacteria,2VS9J@28216|Betaproteobacteria,1K8QA@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_521707_3	390989.JOEG01000004_gene3861	2.792e-53	198.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria,4DFX0@85008|Micromonosporales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	bar	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
LZS3_k127_521707_8	247634.GPB2148_2980	1.002e-25	118.0	COG1950@1|root,COG1950@2|Bacteria	2|Bacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
LZS3_k127_521707_9	194439.CT1335	3.64e-22	101.0	COG4704@1|root,COG4704@2|Bacteria,1FFAT@1090|Chlorobi	1090|Chlorobi	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
LZS3_k127_521707_2	156889.Mmc1_2110	2.084e-73	268.0	COG1453@1|root,COG1453@2|Bacteria,1RAU3@1224|Proteobacteria	1224|Proteobacteria	S	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
LZS3_k127_521707_6	67257.JODR01000025_gene3325	1.546e-34	138.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
LZS3_k127_521707_0	682795.AciX8_3645	1.278e-132	454.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,3Y3QY@57723|Acidobacteria,2JHPJ@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
LZS3_k127_521707_11	1379698.RBG1_1C00001G0140	1.572e-09	67.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD,Excalibur
LZS3_k127_5238349_1	448385.sce4283	3.472e-69	246.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42UM2@68525|delta/epsilon subdivisions,2WR61@28221|Deltaproteobacteria,2YVAU@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS3_k127_5238349_0	502025.Hoch_3215	2.844e-78	277.0	COG0204@1|root,COG0204@2|Bacteria,1N01J@1224|Proteobacteria,42UM7@68525|delta/epsilon subdivisions,2WQN9@28221|Deltaproteobacteria,2Z3CW@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS3_k127_5238349_2	326427.Cagg_0064	3.47e-19	95.0	COG3937@1|root,COG5394@1|root,COG3937@2|Bacteria,COG5394@2|Bacteria,2G77C@200795|Chloroflexi,375VS@32061|Chloroflexia	32061|Chloroflexia	K	PFAM PHA accumulation regulator DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
LZS3_k127_52469_3	47839.CCAU010000009_gene1532	1.465e-137	452.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria,233FN@1762|Mycobacteriaceae	201174|Actinobacteria	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
LZS3_k127_52469_5	1280941.HY2_15200	1.867e-97	349.0	COG1960@1|root,COG1960@2|Bacteria,1R7HF@1224|Proteobacteria,2U3BJ@28211|Alphaproteobacteria,43ZJ8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_52469_1	402881.Plav_1872	3.39e-150	485.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_52469_7	1429916.X566_06320	1.242e-79	274.0	28HG7@1|root,2Z7S3@2|Bacteria,1R60A@1224|Proteobacteria,2U0U9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
LZS3_k127_52469_6	1313172.YM304_18790	5.381e-84	287.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,4CNAF@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
LZS3_k127_52469_9	298654.FraEuI1c_2880	7.726e-73	263.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4ESJA@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_52469_2	1120705.FG95_00410	2.287e-143	471.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,1MY51@1224|Proteobacteria,2UI5H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51,3.1.3.3	ko:K15781	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,HAD
LZS3_k127_52469_4	1250006.JHZZ01000001_gene2037	5.192e-128	417.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1I7FP@117743|Flavobacteriia,3VW20@52959|Polaribacter	976|Bacteroidetes	C	Ketopantoate reductase PanE/ApbA	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
LZS3_k127_52469_8	1137799.GZ78_06900	4.837e-75	264.0	COG4221@1|root,COG4221@2|Bacteria,1MV0A@1224|Proteobacteria,1RSK5@1236|Gammaproteobacteria,1XNGS@135619|Oceanospirillales	135619|Oceanospirillales	S	KR domain	-	-	1.1.1.56	ko:K00039	ko00040,ko01100,map00040,map01100	-	R01895	RC00102	ko00000,ko00001,ko01000	-	-	-	adh_short
LZS3_k127_52469_0	1120936.KB907210_gene5949	1.209e-154	518.0	COG1073@1|root,COG1073@2|Bacteria,2I52S@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5266024_2	928724.SacglDRAFT_02074	2.855e-22	111.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,4DYBI@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.106	ko:K16436	ko00523,ko01055,ko01130,map00523,map01055,map01130	M00797,M00800,M00803	R06426,R06631,R08928	RC00006,RC01514,RC03347	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_5266024_1	1304872.JAGC01000003_gene3787	2.522e-90	309.0	COG0463@1|root,COG0463@2|Bacteria,1RCVF@1224|Proteobacteria,43CNQ@68525|delta/epsilon subdivisions,2WUDG@28221|Deltaproteobacteria,2M9JR@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
LZS3_k127_5266024_0	316274.Haur_3899	1.498e-107	361.0	COG0451@1|root,COG0451@2|Bacteria,2G7KN@200795|Chloroflexi,375A6@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS3_k127_5266553_0	243231.GSU3075	2.909e-110	381.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
LZS3_k127_5284921_0	1192034.CAP_1429	1.471e-70	249.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
LZS3_k127_5284921_1	290397.Adeh_0884	4.575e-58	210.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
LZS3_k127_5285811_7	1244869.H261_02246	1.16e-57	214.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1N17V@1224|Proteobacteria,2TS69@28211|Alphaproteobacteria,2JYVY@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
LZS3_k127_5285811_0	290397.Adeh_1613	0.0	1190.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
LZS3_k127_5285811_6	330214.NIDE2543	1.128e-74	286.0	COG0616@1|root,COG0616@2|Bacteria,3J13W@40117|Nitrospirae	40117|Nitrospirae	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS3_k127_5285811_10	1121406.JAEX01000005_gene2858	2.91e-09	66.0	295U0@1|root,2ZT54@2|Bacteria,1NN8F@1224|Proteobacteria,42X18@68525|delta/epsilon subdivisions,2WSKP@28221|Deltaproteobacteria,2MDYX@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5285811_5	215803.DB30_0080	1.354e-76	265.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2YZ2M@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_5285811_3	644282.Deba_1067	3.53e-102	367.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS3_k127_5285811_9	644282.Deba_1061	3.944e-17	94.0	COG3746@1|root,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria	1224|Proteobacteria	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
LZS3_k127_5285811_8	204669.Acid345_2971	6.389e-40	156.0	COG0704@1|root,COG0704@2|Bacteria,3Y4DI@57723|Acidobacteria,2JJ5M@204432|Acidobacteriia	204432|Acidobacteriia	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
LZS3_k127_5285811_2	1499967.BAYZ01000068_gene1918	2.58e-130	423.0	COG1117@1|root,COG1117@2|Bacteria,2NP2B@2323|unclassified Bacteria	2|Bacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
LZS3_k127_5285811_1	1207063.P24_09261	2.295e-219	694.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,2JQA8@204441|Rhodospirillales	204441|Rhodospirillales	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
LZS3_k127_5285811_4	706587.Desti_4848	5.229e-80	269.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,43CG2@68525|delta/epsilon subdivisions,2X7R2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS3_k127_5286688_0	479434.Sthe_2395	1.121e-20	98.0	COG2120@1|root,COG2120@2|Bacteria,2GB97@200795|Chloroflexi,27XJ6@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_5287824_6	1123256.KB907925_gene1434	0.0001398	49.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,1X4K1@135614|Xanthomonadales	135614|Xanthomonadales	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
LZS3_k127_5287824_5	862908.BMS_1027	7.06e-20	96.0	COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2MTD6@213481|Bdellovibrionales,2WRCE@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS3_k127_5287824_4	404589.Anae109_0394	3.331e-27	127.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,42YY2@68525|delta/epsilon subdivisions,2WUI6@28221|Deltaproteobacteria,2Z0E8@29|Myxococcales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS3_k127_5287824_3	29875.EHK26981	1.326e-30	141.0	29M6E@1|root,2RUFR@2759|Eukaryota,38Y2G@33154|Opisthokonta,3PW5F@4751|Fungi,3RQG1@4890|Ascomycota,21JZ5@147550|Sordariomycetes,3TR07@5125|Hypocreales,3U45W@5129|Hypocreaceae	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5287824_0	765912.Thimo_1107	6.702e-100	338.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RYHN@1236|Gammaproteobacteria,1WXIV@135613|Chromatiales	135613|Chromatiales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
LZS3_k127_5287824_1	335543.Sfum_2415	6.15e-98	327.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,2MQ9V@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
LZS3_k127_5287824_2	1232410.KI421426_gene1462	8.478e-47	189.0	COG1463@1|root,COG1463@2|Bacteria,1Q6ZU@1224|Proteobacteria,42RZ3@68525|delta/epsilon subdivisions,2WNF0@28221|Deltaproteobacteria,43VBW@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
LZS3_k127_5290412_0	7237.FBpp0279540	1.951e-190	615.0	COG1877@1|root,KOG1050@2759|Eukaryota,38EGS@33154|Opisthokonta,3BMA5@33208|Metazoa,3CWD5@33213|Bilateria,41VGH@6656|Arthropoda,3SJ1W@50557|Insecta,451ME@7147|Diptera,45R56@7214|Drosophilidae	33208|Metazoa	G	Catalytic activity. It is involved in the biological process described with trehalose biosynthetic process	Tps1	GO:0003674,GO:0003824,GO:0004805,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044464,GO:0046351,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:1901576	2.4.1.15,3.1.3.12	ko:K01087,ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20,Trehalose_PPase
LZS3_k127_5290412_3	1030157.AFMP01000023_gene867	1.305e-89	306.0	COG2141@1|root,COG2141@2|Bacteria,1R9CH@1224|Proteobacteria,2U46T@28211|Alphaproteobacteria,2K3SC@204457|Sphingomonadales	204457|Sphingomonadales	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_5290412_4	1209984.BN978_03159	6.179e-42	161.0	29XZA@1|root,30JS0@2|Bacteria,2IM0A@201174|Actinobacteria,23F3F@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
LZS3_k127_5290412_5	446468.Ndas_5571	1.206e-14	83.0	COG1051@1|root,COG1051@2|Bacteria,2IKKB@201174|Actinobacteria,4EKZN@85012|Streptosporangiales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS3_k127_5290412_1	1123242.JH636434_gene3342	1.881e-114	378.0	COG0040@1|root,COG0040@2|Bacteria,2IXEV@203682|Planctomycetes	203682|Planctomycetes	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
LZS3_k127_5290412_2	290397.Adeh_1289	1.189e-96	343.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2Z2SY@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_5298624_2	706587.Desti_2982	5.75e-16	92.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
LZS3_k127_5298624_1	889378.Spiaf_1426	8.583e-48	185.0	COG1131@1|root,COG1131@2|Bacteria,2J5JM@203691|Spirochaetes	203691|Spirochaetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_5298624_0	1210884.HG799465_gene12171	6.176e-52	188.0	COG0128@1|root,COG0128@2|Bacteria,2IXRF@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
LZS3_k127_5306768_2	1347369.CCAD010000086_gene1738	4.812e-101	337.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,1ZB27@1386|Bacillus	91061|Bacilli	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
LZS3_k127_5306768_6	264462.Bd3594	3.031e-08	56.0	COG0625@1|root,COG0625@2|Bacteria,1PEUK@1224|Proteobacteria,437SY@68525|delta/epsilon subdivisions,2MUK6@213481|Bdellovibrionales,2X324@28221|Deltaproteobacteria	213481|Bdellovibrionales	H	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N
LZS3_k127_5306768_7	1223544.GSI01S_01_00350	1.586e-05	59.0	COG2706@1|root,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dabb,Lactonase,PKD,VCBS
LZS3_k127_5306768_0	1123320.KB889687_gene951	1.987e-179	582.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_5306768_3	1229780.BN381_10085	5.363e-50	185.0	COG1011@1|root,COG1011@2|Bacteria,2HP8I@201174|Actinobacteria,3UWYW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS3_k127_5306768_1	471852.Tcur_3975	3.421e-123	407.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4EM9F@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5306768_4	1121439.dsat_2036	1.308e-44	184.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YTZ@68525|delta/epsilon subdivisions,2WU37@28221|Deltaproteobacteria,2MHFF@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein, histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_5306768_5	1216976.AX27061_0788	1.426e-16	81.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VHAW@28216|Betaproteobacteria,3T2QW@506|Alcaligenaceae	28216|Betaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	glxR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
LZS3_k127_5312126_0	1128421.JAGA01000002_gene850	9.022e-133	433.0	COG3044@1|root,COG3044@2|Bacteria,2NNSZ@2323|unclassified Bacteria	2|Bacteria	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
LZS3_k127_5312126_1	1286631.X805_30960	1.444e-26	119.0	COG1404@1|root,COG1520@1|root,COG5640@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K14645,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,PQQ_2,Peptidase_S8,SBBP
LZS3_k127_5321976_0	309801.trd_0082	2.081e-172	574.0	COG0366@1|root,COG0366@2|Bacteria,2G5NW@200795|Chloroflexi,27Z45@189775|Thermomicrobia	189775|Thermomicrobia	G	Domain of unknown function (DUF3459)	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
LZS3_k127_5321976_1	596154.Alide2_1233	2.475e-118	396.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VH1N@28216|Betaproteobacteria	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_5326084_0	309801.trd_0260	3.874e-94	319.0	COG0277@1|root,COG0277@2|Bacteria,2G5TM@200795|Chloroflexi,27XF8@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS3_k127_5326084_2	404589.Anae109_1471	5.367e-47	183.0	COG0457@1|root,COG0457@2|Bacteria,1QX47@1224|Proteobacteria,42Y0X@68525|delta/epsilon subdivisions,2WT7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,Zincin_1
LZS3_k127_5326084_4	1519464.HY22_04135	4.456e-12	77.0	COG1309@1|root,COG1309@2|Bacteria,1FFPT@1090|Chlorobi	1090|Chlorobi	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
LZS3_k127_5326084_3	745014.OMB55_00020020	5.262e-14	82.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS3_k127_5326084_1	502025.Hoch_5604	1.495e-87	306.0	COG2211@1|root,COG2211@2|Bacteria,1R0NK@1224|Proteobacteria,43CZ9@68525|delta/epsilon subdivisions,2X87H@28221|Deltaproteobacteria,2Z3MJ@29|Myxococcales	28221|Deltaproteobacteria	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_5327923_1	247634.GPB2148_1774	1.787e-75	263.0	COG1028@1|root,COG1028@2|Bacteria,1R6NY@1224|Proteobacteria,1S0VU@1236|Gammaproteobacteria,1JAJQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	IQR COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_5327923_0	391625.PPSIR1_15265	4.858e-86	291.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
LZS3_k127_5344388_0	1128421.JAGA01000003_gene3049	8.338e-95	321.0	COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS3_k127_5344388_1	1157490.EL26_16960	3.446e-59	222.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,4HAY4@91061|Bacilli,2785U@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
LZS3_k127_5344388_4	767817.Desgi_3791	4.384e-06	54.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
LZS3_k127_5344388_2	290397.Adeh_0078	3.587e-38	149.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5344388_3	502025.Hoch_0054	3.97e-14	81.0	COG0457@1|root,COG0789@1|root,COG0457@2|Bacteria,COG0789@2|Bacteria,1PQD2@1224|Proteobacteria,4323R@68525|delta/epsilon subdivisions,2WXJB@28221|Deltaproteobacteria,2Z10C@29|Myxococcales	28221|Deltaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_1,TPR_17,TPR_8
LZS3_k127_5351358_2	1502850.FG91_01894	2.172e-20	94.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,2K947@204457|Sphingomonadales	204457|Sphingomonadales	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
LZS3_k127_5351358_1	326424.FRAAL0708	1.616e-91	308.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
LZS3_k127_5352818_1	1217720.ALOX01000087_gene3033	2.173e-70	247.0	COG4427@1|root,COG4427@2|Bacteria,1R4EV@1224|Proteobacteria,2TRVP@28211|Alphaproteobacteria,2JWMB@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
LZS3_k127_5352818_6	1123257.AUFV01000005_gene1312	4.339e-36	151.0	COG2329@1|root,COG2329@2|Bacteria,1MZKW@1224|Proteobacteria,1S9N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
LZS3_k127_5352818_7	1411685.U062_00372	1.142e-34	140.0	COG4270@1|root,COG4270@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX,DoxX_2
LZS3_k127_5352818_3	247633.GP2143_13861	5.253e-51	193.0	COG3568@1|root,COG3568@2|Bacteria,1R8HG@1224|Proteobacteria,1SCI2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS3_k127_5352818_0	1476876.JOJO01000010_gene2950	1.518e-92	312.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	rhlG	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
LZS3_k127_5352818_4	1177179.A11A3_11052	1.86e-47	181.0	COG0625@1|root,COG0625@2|Bacteria,1RJVR@1224|Proteobacteria,1S81N@1236|Gammaproteobacteria,1XKSH@135619|Oceanospirillales	135619|Oceanospirillales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3,GST_N_3
LZS3_k127_5352818_8	1038859.AXAU01000011_gene2413	2.389e-33	138.0	COG1733@1|root,COG1733@2|Bacteria,1R6MK@1224|Proteobacteria,2U2KM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,HxlR,SCP2
LZS3_k127_5352818_2	1499967.BAYZ01000048_gene2700	9.362e-67	246.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2,MFS_3
LZS3_k127_5352818_5	502025.Hoch_0331	9.787e-46	172.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,42SD7@68525|delta/epsilon subdivisions,2WPI5@28221|Deltaproteobacteria,2YVK5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
LZS3_k127_5361375_3	1089553.Tph_c08050	2.797e-103	351.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,42I0X@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	nuoF2	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
LZS3_k127_5361375_0	405948.SACE_2432	4.362e-239	786.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4DZUH@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
LZS3_k127_5361375_4	926569.ANT_29930	7.658e-99	360.0	COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi	200795|Chloroflexi	P	Formate/nitrite transporter	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
LZS3_k127_5361375_2	1348663.KCH_16670	1.349e-111	388.0	COG1215@1|root,COG1215@2|Bacteria,2GJZI@201174|Actinobacteria,2M1HV@2063|Kitasatospora	201174|Actinobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS3_k127_5361375_1	1267535.KB906767_gene2263	3.967e-157	502.0	COG0535@1|root,COG0535@2|Bacteria,3Y2JV@57723|Acidobacteria,2JI93@204432|Acidobacteriia	204432|Acidobacteriia	S	TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
LZS3_k127_5366968_0	1379270.AUXF01000005_gene464	2.127e-229	721.0	COG4147@1|root,COG4147@2|Bacteria,1ZUA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sodium:solute symporter family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
LZS3_k127_5366968_1	1278073.MYSTI_06469	5.474e-20	92.0	COG3162@1|root,COG3162@2|Bacteria	2|Bacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
LZS3_k127_5368325_1	751994.AGIG01000007_gene1205	4.299e-46	173.0	COG4764@1|root,COG4764@2|Bacteria,1MVRK@1224|Proteobacteria,1RQ79@1236|Gammaproteobacteria,1J5V9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SLT
LZS3_k127_5368325_0	1385519.N801_11735	1.307e-52	212.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4FFET@85021|Intrasporangiaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_5371371_2	1329516.JPST01000014_gene640	6.895e-46	181.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli,27BZC@186824|Thermoactinomycetaceae	91061|Bacilli	H	SNO glutamine amidotransferase family	pdxT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
LZS3_k127_5371371_0	880073.Calab_3060	4.539e-123	402.0	COG0214@1|root,COG0214@2|Bacteria,2NNZ6@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
LZS3_k127_5371371_1	525897.Dbac_0439	1.262e-68	248.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,43ADQ@68525|delta/epsilon subdivisions,2X5TK@28221|Deltaproteobacteria,2MAD4@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Alanine-glyoxylate amino-transferase	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
LZS3_k127_5391902_6	1828.JOKB01000028_gene2096	0.0001072	53.0	COG2937@1|root,COG2937@2|Bacteria,2GMQF@201174|Actinobacteria,4FWRE@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the GPAT DAPAT family	plsB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_5391902_2	1429916.X566_02405	3.12e-75	266.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,2TUTU@28211|Alphaproteobacteria,3JVSJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	MA20_15935	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_5391902_1	1122604.JONR01000005_gene987	1.631e-101	347.0	COG1073@1|root,COG1073@2|Bacteria,1PQAX@1224|Proteobacteria,1RZIS@1236|Gammaproteobacteria,1X4J1@135614|Xanthomonadales	135614|Xanthomonadales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
LZS3_k127_5391902_5	338966.Ppro_0395	3.173e-18	92.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,42XWP@68525|delta/epsilon subdivisions,2WSIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5391902_0	83406.HDN1F_10410	5.342e-176	566.0	COG1960@1|root,COG1960@2|Bacteria,1R81V@1224|Proteobacteria,1SM92@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_5391902_3	1380391.JIAS01000012_gene4176	4.349e-47	190.0	COG3115@1|root,COG3115@2|Bacteria,1QVM5@1224|Proteobacteria,2TWI6@28211|Alphaproteobacteria,2JZ72@204441|Rhodospirillales	28211|Alphaproteobacteria	D	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
LZS3_k127_5391902_4	768671.ThimaDRAFT_0223	6.137e-31	130.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,1RN1W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
LZS3_k127_5395268_1	1120953.AUBH01000007_gene1851	5.566e-71	246.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,1RZZS@1236|Gammaproteobacteria,4666H@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N_3
LZS3_k127_5395268_0	448385.sce2973	9.92e-167	546.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,43A4M@68525|delta/epsilon subdivisions,2WYKE@28221|Deltaproteobacteria,2Z0NN@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
LZS3_k127_5398138_2	1229780.BN381_410039	6.733e-57	208.0	COG2267@1|root,COG2267@2|Bacteria,2GKPK@201174|Actinobacteria,3UXF2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
LZS3_k127_5398138_1	1121920.AUAU01000005_gene1063	7.097e-103	357.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria	57723|Acidobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
LZS3_k127_5398138_3	321332.CYB_1340	1.387e-41	172.0	COG0328@1|root,COG0328@2|Bacteria,1G12J@1117|Cyanobacteria,1GYK3@1129|Synechococcus	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
LZS3_k127_5398138_0	1120971.AUCA01000026_gene630	6.925e-127	417.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,277Y5@186823|Alicyclobacillaceae	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
LZS3_k127_5440686_3	864051.BurJ1DRAFT_1621	1.053e-45	172.0	COG0406@1|root,COG0406@2|Bacteria,1N83T@1224|Proteobacteria,2VY3M@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
LZS3_k127_5440686_0	1229780.BN381_10333	2.482e-166	530.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,3UWNW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
LZS3_k127_5440686_4	1379698.RBG1_1C00001G0868	1.687e-16	88.0	COG0741@1|root,COG0741@2|Bacteria,2NPKN@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
LZS3_k127_5440686_1	485913.Krac_9502	9.686e-109	374.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	fadB5	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
LZS3_k127_5440686_2	1254432.SCE1572_30730	2.014e-80	290.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,2YZ69@29|Myxococcales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
LZS3_k127_5464855_1	246197.MXAN_0153	1.842e-10	70.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
LZS3_k127_5464855_2	452662.SJA_C1-16730	1.602e-08	67.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_5464855_0	215803.DB30_3401	5.735e-28	130.0	COG4191@1|root,COG4191@2|Bacteria,1QTMQ@1224|Proteobacteria,437ZP@68525|delta/epsilon subdivisions,2X9TE@28221|Deltaproteobacteria,2YUZV@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
LZS3_k127_5464855_3	1168059.KB899087_gene3783	0.0004226	45.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2TSS0@28211|Alphaproteobacteria,3EYQ4@335928|Xanthobacteraceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	MA20_39990	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
LZS3_k127_5471831_2	469383.Cwoe_3159	2.818e-37	143.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,4CSHW@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
LZS3_k127_5471831_0	1108045.GORHZ_022_00020	5.927e-172	566.0	COG2936@1|root,COG2936@2|Bacteria,2IAA6@201174|Actinobacteria,4GA2U@85026|Gordoniaceae	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
LZS3_k127_5471831_1	247634.GPB2148_3291	1.224e-101	363.0	2B7EF@1|root,320I7@2|Bacteria,1NDV8@1224|Proteobacteria,1SG78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5471831_3	479432.Sros_6660	8.252e-30	127.0	2BXSN@1|root,2ZAB3@2|Bacteria,2I1VJ@201174|Actinobacteria,4EPCA@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF4243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4243
LZS3_k127_5472458_4	713586.KB900536_gene696	3.199e-14	83.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad,TadE
LZS3_k127_5472458_2	941449.dsx2_1892	4.17e-94	328.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,42PA6@68525|delta/epsilon subdivisions,2WIIY@28221|Deltaproteobacteria,2M858@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
LZS3_k127_5472458_3	56780.SYN_01491	8.345e-37	149.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,42S07@68525|delta/epsilon subdivisions,2WNR0@28221|Deltaproteobacteria,2MQDE@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	SAF	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ChapFlgA,RcpC,SAF
LZS3_k127_5472458_7	56780.SYN_01494	1.607e-09	69.0	COG4961@1|root,COG4961@2|Bacteria,1N76N@1224|Proteobacteria,42VUR@68525|delta/epsilon subdivisions,2WRQU@28221|Deltaproteobacteria,2MS4W@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS3_k127_5472458_5	555088.DealDRAFT_0815	3.106e-11	72.0	COG4960@1|root,COG4960@2|Bacteria,1UPNE@1239|Firmicutes,24T5Y@186801|Clostridia	186801|Clostridia	OU	PFAM peptidase A24A, prepilin type IV	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
LZS3_k127_5472458_1	1280954.HPO_01942	1.576e-113	373.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	SMP-30 Gluconolaconase	MA20_01275	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
LZS3_k127_5472458_0	639030.JHVA01000001_gene2494	2.67e-125	415.0	COG0443@1|root,COG0443@2|Bacteria,3Y3QN@57723|Acidobacteria,2JIM6@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
LZS3_k127_5476464_7	292459.STH1774	6.766e-05	51.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
LZS3_k127_5476464_2	338963.Pcar_2978	7.205e-39	154.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria,43S1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	aglX	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
LZS3_k127_5476464_4	1144275.COCOR_06247	1.359e-28	129.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2YVFC@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
LZS3_k127_5476464_6	335543.Sfum_0754	2.57e-11	74.0	COG0810@1|root,COG0810@2|Bacteria,1Q5Z4@1224|Proteobacteria,43A9M@68525|delta/epsilon subdivisions,2X230@28221|Deltaproteobacteria,2MQPN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
LZS3_k127_5476464_1	338966.Ppro_3323	4.618e-60	233.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,43UDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS3_k127_5476464_5	1125863.JAFN01000001_gene2298	2.696e-19	99.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42T19@68525|delta/epsilon subdivisions,2WQ0M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
LZS3_k127_5476464_3	404589.Anae109_1309	3.086e-30	123.0	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria,2YVJ6@29|Myxococcales	28221|Deltaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS3_k127_5476464_0	671143.DAMO_2531	2.837e-74	256.0	COG0533@1|root,COG0533@2|Bacteria,2NNXP@2323|unclassified Bacteria	2|Bacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	R10648	RC00070,RC00416	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Peptidase_M22
LZS3_k127_547802_0	1121438.JNJA01000011_gene1841	8.738e-33	147.0	COG4485@1|root,COG4485@2|Bacteria,1QAT5@1224|Proteobacteria,435A8@68525|delta/epsilon subdivisions,2X97C@28221|Deltaproteobacteria,2MFT4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5493673_1	1279019.ARQK01000059_gene922	1.617e-17	96.0	COG2187@1|root,COG2187@2|Bacteria,1R98V@1224|Proteobacteria,1T025@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5493673_0	502025.Hoch_5545	2.196e-78	276.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,1PEHA@1224|Proteobacteria,43A38@68525|delta/epsilon subdivisions,2X24Q@28221|Deltaproteobacteria,2YW67@29|Myxococcales	28221|Deltaproteobacteria	P	TrkA-C domain	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	TrkA_C,TrkA_N
LZS3_k127_5506710_0	309801.trd_A0900	4.156e-110	366.0	COG1060@1|root,COG1060@2|Bacteria,2G7YI@200795|Chloroflexi,27YSR@189775|Thermomicrobia	189775|Thermomicrobia	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
LZS3_k127_5506710_1	398527.Bphyt_4252	1.511e-108	380.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,2VZW4@28216|Betaproteobacteria,1K2DF@119060|Burkholderiaceae	28216|Betaproteobacteria	H	PFAM Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
LZS3_k127_5506710_2	1356854.N007_06615	1.663e-58	216.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,277VV@186823|Alicyclobacillaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS3_k127_5511630_4	1144275.COCOR_05700	6.712e-41	159.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,437FF@68525|delta/epsilon subdivisions,2X2N2@28221|Deltaproteobacteria,2YZX8@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_5511630_5	1211777.BN77_2484	5.773e-24	109.0	2C8CT@1|root,315IS@2|Bacteria,1R3CJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
LZS3_k127_5511630_0	1333998.M2A_0895	2.464e-227	717.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS3_k127_5511630_3	1379698.RBG1_1C00001G1403	1.723e-86	327.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
LZS3_k127_5511630_1	472759.Nhal_1236	5.183e-146	502.0	COG1033@1|root,COG1033@2|Bacteria,1QW3H@1224|Proteobacteria,1RZA3@1236|Gammaproteobacteria,1X2NT@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
LZS3_k127_5511630_2	1125863.JAFN01000001_gene1933	7.385e-97	325.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	AAA ATPase, central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
LZS3_k127_5521405_5	987059.RBXJA2T_00809	4.431e-36	140.0	COG0346@1|root,COG0454@1|root,COG0346@2|Bacteria,COG0456@2|Bacteria,1RI45@1224|Proteobacteria,2WE8E@28216|Betaproteobacteria	28216|Betaproteobacteria	EK	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Glyoxalase
LZS3_k127_5521405_3	215803.DB30_6914	1.086e-61	226.0	COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,43811@68525|delta/epsilon subdivisions,2X3B3@28221|Deltaproteobacteria,2YV70@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4336)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4336
LZS3_k127_5521405_4	1101190.ARWB01000001_gene1992	4.257e-45	173.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2U997@28211|Alphaproteobacteria,36YDP@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Uncharacterized BCR, YaiI/YqxD family COG1671	MA20_27470	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
LZS3_k127_5521405_6	1173020.Cha6605_2234	3.321e-30	126.0	COG1670@1|root,COG1670@2|Bacteria,1G7ZC@1117|Cyanobacteria	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_8
LZS3_k127_5521405_1	247634.GPB2148_3359	1.747e-93	328.0	2DMXI@1|root,32U9G@2|Bacteria,1NFAA@1224|Proteobacteria,1SRGT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5521405_0	472759.Nhal_2234	5.679e-120	406.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1X2AD@135613|Chromatiales	135613|Chromatiales	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_3_3,Peptidase_S8
LZS3_k127_5521405_7	1121403.AUCV01000059_gene3347	2.538e-20	100.0	2DGQ0@1|root,2ZWWC@2|Bacteria,1P87I@1224|Proteobacteria	1224|Proteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
LZS3_k127_5521405_2	404589.Anae109_2417	2.362e-77	273.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,Peptidase_M1
LZS3_k127_5522103_2	1382230.ASAP_1315	0.0002559	46.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,2JQ38@204441|Rhodospirillales	204441|Rhodospirillales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
LZS3_k127_5522103_0	251221.35214644	6.66e-235	742.0	COG1166@1|root,COG1166@2|Bacteria,1G1C4@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
LZS3_k127_5522103_1	1313172.YM304_26210	3.864e-175	562.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4CMW5@84992|Acidimicrobiia	201174|Actinobacteria	CJ	CoA binding domain	acdA1	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
LZS3_k127_5533773_1	1229780.BN381_290057	4.124e-67	237.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,3UXH6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_5533773_0	402881.Plav_2519	2.067e-189	605.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,1JPX5@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Sulfatase	pehA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_5548431_2	1121861.KB899937_gene4028	3.149e-17	94.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JP9V@204441|Rhodospirillales	28211|Alphaproteobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
LZS3_k127_5548431_1	1183438.GKIL_1123	3.851e-73	269.0	COG1173@1|root,COG1173@2|Bacteria,1G0CD@1117|Cyanobacteria	1117|Cyanobacteria	P	'ABC-type dipeptide oligopeptide nickel transport	appC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
LZS3_k127_5548431_0	1123256.KB907928_gene1936	3.133e-78	272.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1X5Q2@135614|Xanthomonadales	135614|Xanthomonadales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
LZS3_k127_5579869_1	439235.Dalk_2065	6.994e-16	80.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,42N51@68525|delta/epsilon subdivisions,2WKBV@28221|Deltaproteobacteria,2MIQE@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_5579869_0	460265.Mnod_1226	1.367e-171	549.0	COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,2TQRB@28211|Alphaproteobacteria,1JQZ4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
LZS3_k127_560507_5	880072.Desac_1820	9.754e-13	74.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DNA_circ_N,Gram_pos_anchor
LZS3_k127_560507_6	357808.RoseRS_1743	9.324e-10	70.0	COG4932@1|root,COG4932@2|Bacteria,2G7MG@200795|Chloroflexi,376NW@32061|Chloroflexia	32061|Chloroflexia	M	PFAM Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_560507_1	1382303.JPOM01000001_gene1759	1.994e-81	289.0	COG1804@1|root,COG1804@2|Bacteria,1MWPB@1224|Proteobacteria,2U1YE@28211|Alphaproteobacteria,2KFDM@204458|Caulobacterales	204458|Caulobacterales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_560507_3	1142394.PSMK_09430	2.919e-69	249.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Cellulase,Glyco_hydro_32C,Glyco_hydro_32N,RicinB_lectin_2
LZS3_k127_560507_0	1123368.AUIS01000033_gene1370	9.057e-100	334.0	COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria	1224|Proteobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_560507_2	1168065.DOK_06849	2.633e-80	278.0	COG0451@1|root,COG0451@2|Bacteria,1R2A6@1224|Proteobacteria,1SIAD@1236|Gammaproteobacteria,1J9KK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_560507_4	1380390.JIAT01000009_gene1919	7.162e-15	78.0	2AV96@1|root,31M03@2|Bacteria,2HPQD@201174|Actinobacteria,4CR3C@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_560538_1	1320556.AVBP01000015_gene905	7.032e-69	242.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2TSQC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	MA20_16655	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,DUF676,Hydrolase_4
LZS3_k127_560538_2	1211815.CBYP010000062_gene3190	6.443e-46	181.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4ERRT@85013|Frankiales	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
LZS3_k127_560538_0	479432.Sros_5575	5.132e-103	376.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria,4EHY7@85012|Streptosporangiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS3_k127_560538_3	1121952.ATXT01000004_gene1127	3.435e-11	76.0	COG2373@1|root,COG3468@1|root,COG2373@2|Bacteria,COG3468@2|Bacteria,2HCJX@201174|Actinobacteria,4FTDJ@85023|Microbacteriaceae	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
LZS3_k127_561066_0	1242864.D187_005763	9.667e-197	633.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS3_k127_561066_1	706587.Desti_1416	5.269e-84	291.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MQ9Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
LZS3_k127_561066_2	1049564.TevJSym_be00090	4.146e-27	117.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,1J63F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
LZS3_k127_5619251_0	1206726.BAFV01000018_gene1167	2.879e-107	359.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4FUI3@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_5619251_1	1123279.ATUS01000003_gene460	1.634e-52	188.0	COG1545@1|root,COG1545@2|Bacteria,1RIV9@1224|Proteobacteria,1S7WJ@1236|Gammaproteobacteria,1J60Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
LZS3_k127_5619251_2	1123320.KB889562_gene6879	3.285e-24	119.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N,ketoacyl-synt
LZS3_k127_564264_2	384676.PSEEN0347	4.571e-18	97.0	COG4706@1|root,COG4706@2|Bacteria,1N00A@1224|Proteobacteria,1S9E9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	3-hydroxylacyl-(Acyl carrier protein) dehydratase	fabA1	-	-	-	-	-	-	-	-	-	-	-	FabA
LZS3_k127_564264_1	1249634.D781_0861	2.021e-71	267.0	COG1216@1|root,COG4261@1|root,COG1216@2|Bacteria,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,1RNKV@1236|Gammaproteobacteria,400M5@613|Serratia	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	ycdQ	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Lip_A_acyltrans
LZS3_k127_564264_0	266264.Rmet_4381	6.977e-88	306.0	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,2VIYA@28216|Betaproteobacteria,1JZSG@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	amp-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
LZS3_k127_5657003_0	204669.Acid345_2471	3.514e-119	394.0	COG1960@1|root,COG1960@2|Bacteria,3Y2NA@57723|Acidobacteria,2JII2@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_5657003_1	926550.CLDAP_10880	6.793e-33	145.0	COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi	200795|Chloroflexi	K	Fibronectin-binding A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
LZS3_k127_5657003_2	1385515.N791_09215	8.792e-10	68.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
LZS3_k127_5667256_10	118173.KB235914_gene2476	2.401e-49	184.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_5667256_9	883078.HMPREF9695_02589	1.977e-50	202.0	COG1835@1|root,COG1835@2|Bacteria,1R4CU@1224|Proteobacteria,2U2AF@28211|Alphaproteobacteria,3JXBG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
LZS3_k127_5667256_2	290397.Adeh_0870	1.413e-130	435.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,42MWU@68525|delta/epsilon subdivisions,2WKCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
LZS3_k127_5667256_0	1267535.KB906767_gene3396	3.964e-213	666.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
LZS3_k127_5667256_11	1123024.AUII01000016_gene1273	1.943e-30	136.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4E613@85010|Pseudonocardiales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
LZS3_k127_5667256_7	1157708.KB907457_gene2563	1.022e-68	237.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,2VRWE@28216|Betaproteobacteria,4AEHP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
LZS3_k127_5667256_6	1192034.CAP_6386	7.44e-84	286.0	COG0625@1|root,COG0625@2|Bacteria,1R7YC@1224|Proteobacteria	1224|Proteobacteria	O	COG0695 glutaredoxin and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
LZS3_k127_5667256_5	1048339.KB913029_gene1045	5.179e-84	299.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria,4EV45@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_5667256_3	1121272.KB903254_gene6617	1.198e-120	411.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,4D9A0@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839,PD40
LZS3_k127_5667256_4	861299.J421_5736	5.229e-97	323.0	KOG1573@1|root,2Z822@2|Bacteria	2|Bacteria	S	Inositol oxygenase	-	-	1.13.99.1	ko:K00469	ko00053,ko00562,map00053,map00562	-	R01184	RC00465	ko00000,ko00001,ko01000	-	-	-	MIOX
LZS3_k127_5667256_13	314278.NB231_01898	9.869e-17	95.0	28N07@1|root,2ZB6S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5667256_12	1343739.PAP_04595	1.331e-17	96.0	COG1011@1|root,arCOG02291@2157|Archaea,2XUJR@28890|Euryarchaeota,2431M@183968|Thermococci	183968|Thermococci	S	haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS3_k127_5667256_1	575540.Isop_2691	6.024e-149	482.0	COG0172@1|root,COG0172@2|Bacteria,2IXGP@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
LZS3_k127_5667256_8	243231.GSU0102	1.216e-67	233.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,43TPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
LZS3_k127_5669452_1	880072.Desac_1499	6.124e-28	124.0	COG2204@1|root,COG3605@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3605@2|Bacteria,COG4191@2|Bacteria,1MU0N@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_5669452_0	1232410.KI421428_gene1165	2.685e-110	363.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,42M48@68525|delta/epsilon subdivisions,2WISV@28221|Deltaproteobacteria,43S1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
LZS3_k127_5671224_1	1124780.ANNU01000003_gene1417	2.473e-24	108.0	COG0821@1|root,COG0821@2|Bacteria,4NE63@976|Bacteroidetes,47KGW@768503|Cytophagia	976|Bacteroidetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
LZS3_k127_5671224_0	1125863.JAFN01000001_gene3028	1.392e-306	962.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS3_k127_5671224_2	1121439.dsat_1262	4.537e-16	87.0	2ARE9@1|root,31GQB@2|Bacteria,1QEDX@1224|Proteobacteria,43EE7@68525|delta/epsilon subdivisions,2X0FZ@28221|Deltaproteobacteria,2MC7I@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
LZS3_k127_5674047_0	861299.J421_1168	4.463e-87	299.0	COG1744@1|root,COG1744@2|Bacteria,1ZSMV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
LZS3_k127_5674897_3	366602.Caul_2669	1.31e-14	78.0	COG1309@1|root,COG1309@2|Bacteria,1N208@1224|Proteobacteria,2UDE9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_5674897_0	1333998.M2A_0798	2.121e-86	303.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2U0BA@28211|Alphaproteobacteria,4BT4A@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B,Lactamase_B_2
LZS3_k127_5674897_1	1163617.SCD_n02288	3.871e-60	236.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_9,Response_reg
LZS3_k127_5674897_2	748247.AZKH_2026	5.4e-60	235.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV5M@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,Response_reg
LZS3_k127_5703054_0	653733.Selin_1133	9.081e-121	406.0	COG2255@1|root,COG2255@2|Bacteria	2|Bacteria	L	four-way junction helicase activity	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
LZS3_k127_5703054_1	234267.Acid_0956	3.95e-37	147.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria	57723|Acidobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
LZS3_k127_5713532_0	338963.Pcar_1922	2.691e-25	122.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,43S9U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted permease YjgP/YjgQ family	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
LZS3_k127_5713532_1	1293054.HSACCH_02547	2.693e-17	91.0	COG0859@1|root,COG0859@2|Bacteria,1TRN2@1239|Firmicutes,24W0F@186801|Clostridia,3WB26@53433|Halanaerobiales	186801|Clostridia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_5714134_2	933262.AXAM01000008_gene1922	3.259e-54	200.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MHPT@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS3_k127_5714134_0	1395587.P364_0129145	2.557e-88	312.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,26RR9@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
LZS3_k127_5714134_1	1144275.COCOR_03821	2.683e-69	245.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
LZS3_k127_5726069_4	876044.IMCC3088_2203	1.029e-09	71.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Stress-induced protein	yicC	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
LZS3_k127_5726069_2	118005.AWNK01000006_gene1328	1.968e-64	248.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
LZS3_k127_5726069_0	404589.Anae109_3216	3.594e-126	430.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,42R49@68525|delta/epsilon subdivisions,2WNEZ@28221|Deltaproteobacteria,2YU32@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
LZS3_k127_5726069_1	237368.SCABRO_02247	1.597e-72	260.0	COG1216@1|root,COG1216@2|Bacteria,2J0AR@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS3_k127_5726069_3	237368.SCABRO_03096	2.147e-17	85.0	COG0859@1|root,COG0859@2|Bacteria,2IXD5@203682|Planctomycetes	203682|Planctomycetes	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_572940_1	716928.AJQT01000094_gene4412	4.333e-48	194.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria,4B9EZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	ABC transporter, ATP-binding protein	ybhF	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_572940_5	1144275.COCOR_01445	1.704e-21	109.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42NC1@68525|delta/epsilon subdivisions,2WMKG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS3_k127_572940_4	882.DVU_0057	1.098e-25	123.0	COG1309@1|root,COG1309@2|Bacteria,1NDME@1224|Proteobacteria,42MYP@68525|delta/epsilon subdivisions,2WKKZ@28221|Deltaproteobacteria,2MCQF@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Transcriptional regulator TetR	-	-	-	-	-	-	-	-	-	-	-	-	DUF1956,TetR_N
LZS3_k127_572940_7	685727.REQ_36880	1.371e-08	66.0	COG2030@1|root,COG2030@2|Bacteria,2IFCJ@201174|Actinobacteria,4FVTB@85025|Nocardiaceae	201174|Actinobacteria	I	MaoC like domain	hadA	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
LZS3_k127_572940_8	595537.Varpa_2254	1.507e-06	61.0	COG2030@1|root,COG2030@2|Bacteria,1RJ2Z@1224|Proteobacteria,2VT2I@28216|Betaproteobacteria,4AEQB@80864|Comamonadaceae	28216|Betaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
LZS3_k127_572940_3	748247.AZKH_2144	7.444e-26	121.0	COG0613@1|root,COG0613@2|Bacteria,1RF04@1224|Proteobacteria,2W16S@28216|Betaproteobacteria,2KYJS@206389|Rhodocyclales	206389|Rhodocyclales	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
LZS3_k127_572940_2	1123321.KB905816_gene2717	3.5e-28	131.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria	201174|Actinobacteria	EGP	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
LZS3_k127_572940_0	1382306.JNIM01000001_gene1425	2.071e-113	383.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_572940_6	47716.JOFH01000015_gene5782	9.005e-11	66.0	COG0599@1|root,COG2021@1|root,COG0599@2|Bacteria,COG2021@2|Bacteria,2GITB@201174|Actinobacteria	201174|Actinobacteria	I	decarboxylase	pcaC	-	3.1.1.24,4.1.1.44	ko:K01607,ko:K14727	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991,R03470	RC00825,RC00938	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,CMD
LZS3_k127_574051_1	1237149.C900_03017	3.401e-32	135.0	COG0457@1|root,COG0457@2|Bacteria,4PPR7@976|Bacteroidetes	976|Bacteroidetes	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_574051_0	411684.HPDFL43_18427	7.561e-67	244.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,43GZQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	Acyl-CoA thioesterase	tesB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
LZS3_k127_5752696_3	1123052.AUDF01000004_gene1995	0.0008134	46.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4FMGH@85023|Microbacteriaceae	201174|Actinobacteria	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
LZS3_k127_5752696_2	1121405.dsmv_3287	3.385e-19	94.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	CP_0026	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
LZS3_k127_5752696_0	96561.Dole_2118	1.159e-141	472.0	COG0318@1|root,COG0318@2|Bacteria,1NUXN@1224|Proteobacteria	1224|Proteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
LZS3_k127_5752696_1	290397.Adeh_2386	8.38e-20	96.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS3_k127_5763914_2	1453501.JELR01000002_gene374	8.393e-28	117.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,4642K@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_3924,iPC815.YPO3501	Pterin_bind
LZS3_k127_5763914_0	1232410.KI421415_gene3040	3.374e-238	773.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,43S6Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	FtsH Extracellular	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS3_k127_5763914_1	1163671.JAGI01000002_gene3528	9.936e-45	175.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,36EWX@31979|Clostridiaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
LZS3_k127_5763914_3	47716.JOFH01000005_gene1370	6.987e-18	94.0	COG2030@1|root,COG2030@2|Bacteria,2GXE5@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
LZS3_k127_5765298_0	82654.Pse7367_3071	1.058e-155	506.0	COG0082@1|root,COG0082@2|Bacteria,1G12S@1117|Cyanobacteria,1H8F2@1150|Oscillatoriales	1117|Cyanobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.aroC	Chorismate_synt
LZS3_k127_5765298_1	1282876.BAOK01000001_gene3166	4.147e-106	351.0	COG0673@1|root,COG0673@2|Bacteria,1MXDE@1224|Proteobacteria,2TSGR@28211|Alphaproteobacteria,4BRMC@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_5768483_1	555793.WSK_4000	5.411e-50	186.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4RU@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
LZS3_k127_5768483_2	1123024.AUII01000015_gene3758	1.602e-21	95.0	COG1141@1|root,COG1141@2|Bacteria,2GT1Y@201174|Actinobacteria	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	fdxD_2	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
LZS3_k127_5768483_0	1313172.YM304_12040	9.901e-95	323.0	COG0491@1|root,COG0491@2|Bacteria,2IBQF@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
LZS3_k127_5768483_3	1192034.CAP_8078	3.756e-21	107.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2YV8N@29|Myxococcales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
LZS3_k127_5776676_0	644966.Tmar_1144	1.033e-69	251.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,3WCCS@538999|Clostridiales incertae sedis	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
LZS3_k127_5776676_1	861299.J421_2993	6.863e-15	84.0	COG4704@1|root,COG4704@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	DUF2141,MipA
LZS3_k127_5782958_1	383372.Rcas_1497	4.942e-60	215.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,374X4@32061|Chloroflexia	32061|Chloroflexia	E	PFAM gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_5782958_0	717785.HYPMC_2111	3.882e-73	255.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,3N8SM@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.1.1.41,4.2.1.17	ko:K01692,ko:K11264	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R00923,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00097,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_5782958_2	398767.Glov_3469	4.941e-29	125.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
LZS3_k127_5799959_0	316055.RPE_2080	2.133e-142	455.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,3JSY1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS3_k127_5799959_1	1313172.YM304_41440	3.081e-59	212.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4CNYR@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_582007_0	378806.STAUR_2110	2.565e-168	546.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2YU9T@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS3_k127_582007_1	862908.BMS_1327	2.687e-96	347.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2MSQV@213481|Bdellovibrionales,2WIJN@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS3_k127_5837513_4	1499967.BAYZ01000171_gene5600	6.133e-26	124.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS3_k127_5837513_0	1122611.KB903945_gene1369	6.106e-96	330.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4EFWM@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	fadE36	-	-	-	-	-	-	-	-	-	-	-	APH
LZS3_k127_5837513_1	96561.Dole_1514	6.569e-66	241.0	COG2200@1|root,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,42N7E@68525|delta/epsilon subdivisions,2WK3K@28221|Deltaproteobacteria,2MM49@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
LZS3_k127_5837513_2	72019.SARC_06571T0	3.553e-49	183.0	COG1011@1|root,COG3173@1|root,KOG1469@2759|Eukaryota,KOG3085@2759|Eukaryota,38BWX@33154|Opisthokonta	33154|Opisthokonta	I	very-long-chain-acyl-CoA dehydrogenase activity	ACAD10	GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.3.8.7	ko:K00249,ko:K11729	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,HAD_2,Hydrolase
LZS3_k127_5837513_5	1232410.KI421421_gene3696	5.893e-05	55.0	COG0745@1|root,COG0745@2|Bacteria,1QZ5N@1224|Proteobacteria,4307W@68525|delta/epsilon subdivisions,2X7RC@28221|Deltaproteobacteria,43UV3@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
LZS3_k127_5837513_3	493475.GARC_1156	3.116e-34	138.0	COG3788@1|root,COG3788@2|Bacteria,1NBHH@1224|Proteobacteria,1SBVZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
LZS3_k127_5837513_6	713586.KB900536_gene2820	0.0001032	45.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS3_k127_5864730_2	2074.JNYD01000018_gene2760	5.246e-13	72.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4DXU7@85010|Pseudonocardiales	201174|Actinobacteria	H	TIGRFAM molybdenum cofactor synthesis domain	moeA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS3_k127_5864730_1	269799.Gmet_2562	3.636e-62	228.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
LZS3_k127_5864730_0	243231.GSU1003	6.927e-136	467.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_5867060_3	1379698.RBG1_1C00001G0682	8.197e-13	82.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K20306	-	-	-	-	ko00000,ko04131	-	-	-	Lipase_GDSL,Lipase_GDSL_2
LZS3_k127_5867060_0	1313172.YM304_15410	3.916e-146	486.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_5867060_1	1144275.COCOR_02898	1.11e-66	245.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_5867060_2	1336245.JAGO01000010_gene697	7.34e-59	214.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1XI6F@135619|Oceanospirillales	135619|Oceanospirillales	Q	ABC transporter maintaining outer membrane lipid asymmetry	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
LZS3_k127_5871353_0	6500.XP_005103394.1	1.849e-261	814.0	COG1838@1|root,2QT04@2759|Eukaryota,39WD1@33154|Opisthokonta,3BI53@33208|Metazoa,3D3TJ@33213|Bilateria	33208|Metazoa	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
LZS3_k127_5871353_4	326424.FRAAL4491	2.976e-77	271.0	COG0583@1|root,COG0583@2|Bacteria,2H6E4@201174|Actinobacteria,4EWHP@85013|Frankiales	201174|Actinobacteria	K	LysR substrate binding domain	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
LZS3_k127_5871353_5	1218084.BBJK01000083_gene5674	1.076e-55	201.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,1K08S@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
LZS3_k127_5871353_3	502025.Hoch_5653	1.882e-91	311.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,42NY7@68525|delta/epsilon subdivisions,2WIXK@28221|Deltaproteobacteria,2Z364@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
LZS3_k127_5871353_6	251229.Chro_5138	2.16e-49	193.0	28JE3@1|root,2Z98B@2|Bacteria,1G13G@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5871353_8	1278078.G419_10507	3.107e-31	128.0	COG2050@1|root,COG2050@2|Bacteria,2IKTU@201174|Actinobacteria,4G1AK@85025|Nocardiaceae	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS3_k127_5871353_2	1370120.AUWR01000072_gene911	4.311e-112	375.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,234PV@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_5871353_9	251221.35213029	8.49e-29	122.0	COG2020@1|root,COG2020@2|Bacteria,1GB2G@1117|Cyanobacteria	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
LZS3_k127_5871353_1	1000565.METUNv1_04052	2.22e-124	417.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
LZS3_k127_5871353_7	1485545.JQLW01000007_gene828	1.08e-34	141.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdxA	GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
LZS3_k127_5871353_10	1521187.JPIM01000164_gene923	2.149e-25	107.0	COG3118@1|root,COG3118@2|Bacteria,2G90Y@200795|Chloroflexi,376KV@32061|Chloroflexia	32061|Chloroflexia	O	PFAM Thioredoxin domain	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
LZS3_k127_5912111_1	448385.sce2228	1.824e-57	203.0	COG1408@1|root,COG1408@2|Bacteria,1Q3AY@1224|Proteobacteria,43923@68525|delta/epsilon subdivisions,2X47Q@28221|Deltaproteobacteria,2YYFK@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_5912111_0	240015.ACP_3313	2.078e-118	405.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JMQ0@204432|Acidobacteriia	204432|Acidobacteriia	F	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
LZS3_k127_5912111_4	331869.BAL199_25019	1.322e-09	70.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,4BQWJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS3_k127_5912111_3	266834.SMc03822	1.144e-12	80.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,4BF34@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS3_k127_5912111_2	269796.Rru_A2354	2.229e-31	137.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2TQRV@28211|Alphaproteobacteria,2JQ4S@204441|Rhodospirillales	204441|Rhodospirillales	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
LZS3_k127_5912236_2	1313172.YM304_04470	1.969e-34	135.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
LZS3_k127_5912236_0	243231.GSU0496	5.7e-86	299.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,43SP7@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
LZS3_k127_5912236_1	330214.NIDE1083	4.627e-55	197.0	COG1136@1|root,COG1136@2|Bacteria,3J10N@40117|Nitrospirae	40117|Nitrospirae	V	Evidence 2b Function of strongly homologous gene	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_5926611_1	1232410.KI421418_gene2158	1.496e-121	422.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,43UC5@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Bacterial type II/III secretion system short domain	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
LZS3_k127_5926611_0	290397.Adeh_0685	4.359e-181	594.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YUKY@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
LZS3_k127_5926611_2	404589.Anae109_0728	2.914e-107	361.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
LZS3_k127_5926611_4	396588.Tgr7_0231	5.592e-36	156.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,1WY8U@135613|Chromatiales	135613|Chromatiales	U	general secretion pathway protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
LZS3_k127_5926611_7	1121918.ARWE01000001_gene733	6.919e-06	58.0	COG2165@1|root,COG2165@2|Bacteria,1NZKC@1224|Proteobacteria,430RG@68525|delta/epsilon subdivisions,2WVSQ@28221|Deltaproteobacteria,43V4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5926611_6	745014.OMB55_00004790	9.528e-11	75.0	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,1S2N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG3156 Type II secretory pathway component PulK	gspK	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
LZS3_k127_5926611_3	290397.Adeh_0678	1.184e-43	178.0	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2YVKD@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilus assembly protein PilM;	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
LZS3_k127_5926611_5	1125863.JAFN01000001_gene2024	1.951e-12	81.0	COG3149@1|root,COG3149@2|Bacteria,1NEZ3@1224|Proteobacteria,42WMP@68525|delta/epsilon subdivisions,2WSE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
LZS3_k127_592674_1	768671.ThimaDRAFT_4173	3.606e-86	292.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
LZS3_k127_592674_0	765911.Thivi_3073	3.575e-160	509.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales	135613|Chromatiales	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS3_k127_5932039_0	1304878.AUGD01000003_gene2748	1.04e-54	208.0	COG0596@1|root,COG0596@2|Bacteria,1Q4C8@1224|Proteobacteria,2TTW5@28211|Alphaproteobacteria,3JTEC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	MA20_23630	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_5975451_0	876044.IMCC3088_1489	8.724e-140	462.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,1RRN8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	ygcU	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS3_k127_5975451_1	1283283.ATXA01000007_gene3841	4.456e-05	48.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4ES07@85013|Frankiales	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
LZS3_k127_5979572_1	290397.Adeh_0078	1.564e-36	145.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5979572_0	1229780.BN381_250119	1.338e-128	419.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,3UX8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
LZS3_k127_5979572_2	59538.XP_005978164.1	1.733e-14	78.0	COG0596@1|root,KOG4409@2759|Eukaryota	2759|Eukaryota	EH	1-acylglycerol-3-phosphate O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
LZS3_k127_5980169_2	1396141.BATP01000023_gene675	1.425e-10	65.0	2DDIT@1|root,2ZI99@2|Bacteria,46WMJ@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS3_k127_5980169_0	1116472.MGMO_20c00270	1.25e-98	336.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,1XDKP@135618|Methylococcales	1236|Gammaproteobacteria	C	Tryptophan halogenase	pltM	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
LZS3_k127_5980169_1	656024.FsymDg_3050	4.195e-29	134.0	COG1233@1|root,COG1233@2|Bacteria,2GP0A@201174|Actinobacteria	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS3_k127_5986964_1	44056.XP_009032174.1	1.076e-10	71.0	COG0484@1|root,KOG0712@2759|Eukaryota	2759|Eukaryota	O	heat shock protein binding	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C
LZS3_k127_5986964_0	316274.Haur_1559	7.887e-102	342.0	COG3173@1|root,COG3173@2|Bacteria,2G5RM@200795|Chloroflexi	200795|Chloroflexi	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
LZS3_k127_6000434_1	1265313.HRUBRA_02184	1.209e-06	58.0	COG3105@1|root,COG3105@2|Bacteria,1N25P@1224|Proteobacteria,1SE1A@1236|Gammaproteobacteria,1J6VW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09908	-	-	-	-	ko00000	-	-	-	DUF1043
LZS3_k127_6000434_0	886293.Sinac_1421	1.152e-146	472.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.1.5	ko:K00128,ko:K00129	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_6000510_2	404589.Anae109_1145	2.402e-28	119.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
LZS3_k127_6000510_0	269799.Gmet_1591	1.338e-230	736.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,43TFC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
LZS3_k127_6000510_1	1123060.JONP01000003_gene223	2.802e-52	188.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2JS8T@204441|Rhodospirillales	204441|Rhodospirillales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
LZS3_k127_6002248_2	449447.MAE_48630	3.814e-20	93.0	COG1598@1|root,COG1598@2|Bacteria,1GF2K@1117|Cyanobacteria	1117|Cyanobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
LZS3_k127_6002248_1	1499967.BAYZ01000096_gene4319	1.374e-28	115.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
LZS3_k127_6002248_0	1192034.CAP_6595	5.147e-79	274.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2YUH9@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS3_k127_6014371_1	710686.Mycsm_00629	1.723e-39	157.0	COG1309@1|root,COG1309@2|Bacteria,2IGNJ@201174|Actinobacteria,238R0@1762|Mycobacteriaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
LZS3_k127_6014371_0	1101190.ARWB01000001_gene2313	1.572e-128	436.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria,3719A@31993|Methylocystaceae	28211|Alphaproteobacteria	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
LZS3_k127_6014371_2	443218.AS9A_3702	1.157e-07	64.0	COG2050@1|root,COG2050@2|Bacteria,2HT7R@201174|Actinobacteria,235NN@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
LZS3_k127_602107_2	63737.Npun_R6586	3.54e-10	72.0	COG2706@1|root,COG2706@2|Bacteria,1G8VQ@1117|Cyanobacteria,1HTQN@1161|Nostocales	1117|Cyanobacteria	G	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,Lactonase
LZS3_k127_602107_1	926690.KE386573_gene1933	6.411e-46	192.0	COG2820@1|root,arCOG01324@2157|Archaea,2XSWN@28890|Euryarchaeota,23SKE@183963|Halobacteria	183963|Halobacteria	F	Uridine phosphorylase	udp2	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS3_k127_602107_0	1123354.AUDR01000012_gene1738	1.855e-186	629.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,1KSHC@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Bacterial DNA topoisomeraes I ATP-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
LZS3_k127_6021521_2	871963.Desdi_2145	1.086e-08	64.0	COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,24HXX@186801|Clostridia,262JG@186807|Peptococcaceae	186801|Clostridia	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_6021521_1	331869.BAL199_03239	2.2e-34	144.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2U3H2@28211|Alphaproteobacteria,4BQXD@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_6021521_0	76114.c1A84	7.221e-103	349.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
LZS3_k127_6029692_1	1123320.KB889717_gene7662	4.037e-127	430.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	cyp	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
LZS3_k127_6029692_0	1205680.CAKO01000040_gene876	7.439e-196	621.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JPPM@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_6029692_2	1125863.JAFN01000001_gene533	8.354e-73	278.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,43BK5@68525|delta/epsilon subdivisions,2X6Y1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6029692_3	1283300.ATXB01000001_gene1884	1.437e-15	89.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Cu-binding_MopE,DUF4214,Glyco_hydro_16,Peptidase_M10
LZS3_k127_6030914_1	290397.Adeh_1694	4.727e-43	167.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2Z0ST@29|Myxococcales	28221|Deltaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
LZS3_k127_6030914_0	191610.CATYP_08455	7.308e-75	271.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,22K6P@1653|Corynebacteriaceae	201174|Actinobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
LZS3_k127_6030914_2	525897.Dbac_2834	2.074e-10	72.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MB1P@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
LZS3_k127_6046311_0	1242864.D187_000606	1.167e-78	271.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2X24A@28221|Deltaproteobacteria,2Z1T0@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_6046311_1	1458357.BG58_25900	1.222e-39	158.0	COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,2VPHU@28216|Betaproteobacteria,1KGYJ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
LZS3_k127_6059377_4	1437882.AZRU01000102_gene3871	1.141e-47	181.0	COG2404@1|root,COG2404@2|Bacteria,1MXEH@1224|Proteobacteria,1SADM@1236|Gammaproteobacteria,1YI8A@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	phosphoesterase DHHA1	-	-	-	-	-	-	-	-	-	-	-	-	DHHA1
LZS3_k127_6059377_1	1108045.GORHZ_141_00840	2.321e-121	402.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4GCJP@85026|Gordoniaceae	201174|Actinobacteria	V	Beta-lactamase	lipL	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_6059377_3	1292034.OR37_04025	7.402e-86	323.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria,2KHIG@204458|Caulobacterales	204458|Caulobacterales	I	PFAM alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_6059377_0	926550.CLDAP_05760	1.489e-165	550.0	COG1501@1|root,COG1501@2|Bacteria,2G5TX@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
LZS3_k127_6059377_5	477184.KYC_09240	1.612e-19	96.0	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,2VUB0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
LZS3_k127_6059377_8	338966.Ppro_3123	3.589e-07	57.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,42V7U@68525|delta/epsilon subdivisions,2WS0W@28221|Deltaproteobacteria,43W28@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6059377_10	35128.Thaps24962	0.0005325	51.0	2EQX7@1|root,2SG2S@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6059377_2	1198452.Jab_2c15870	2.961e-110	370.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2WEEX@28216|Betaproteobacteria,478W4@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_6059377_9	1121448.DGI_1222	3.648e-05	51.0	COG0715@1|root,COG5002@1|root,COG0715@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria,2MH9G@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg,dCache_3
LZS3_k127_6059377_7	290397.Adeh_3888	9.645e-09	66.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WJNC@28221|Deltaproteobacteria,2Z30Z@29|Myxococcales	28221|Deltaproteobacteria	EH	Anthranilate synthase component I, N terminal region	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
LZS3_k127_6082621_1	351627.Csac_2528	1.38e-106	366.0	COG3934@1|root,COG3934@2|Bacteria,1V19K@1239|Firmicutes,24DHA@186801|Clostridia	186801|Clostridia	G	hydrolase family 5	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	CBM_11,CBM_X2,Cellulase,Dockerin_1,fn3
LZS3_k127_6082621_0	1123023.JIAI01000010_gene8577	6.744e-114	377.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4E43A@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
LZS3_k127_6083542_0	1118054.CAGW01000068_gene1896	1.203e-141	460.0	COG1960@1|root,COG1960@2|Bacteria,1TSN3@1239|Firmicutes,4HB0T@91061|Bacilli,2725X@186822|Paenibacillaceae	91061|Bacilli	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_6087524_1	1379270.AUXF01000002_gene1843	7.741e-11	65.0	COG4191@1|root,COG4191@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
LZS3_k127_6087524_0	526225.Gobs_2081	1.656e-88	302.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4EUBM@85013|Frankiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
LZS3_k127_6091119_2	1125863.JAFN01000001_gene358	4.881e-25	108.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
LZS3_k127_6091119_1	240015.ACP_2970	3.743e-94	323.0	COG0167@1|root,COG0167@2|Bacteria,3Y2K1@57723|Acidobacteria,2JHXE@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS3_k127_6091119_3	1200792.AKYF01000011_gene3438	1.511e-22	107.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli,26R8B@186822|Paenibacillaceae	91061|Bacilli	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
LZS3_k127_6091119_0	880072.Desac_2286	3.838e-138	463.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2MQWA@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
LZS3_k127_6096304_3	443144.GM21_0765	2.555e-41	169.0	COG2199@1|root,COG3706@2|Bacteria,1MZZV@1224|Proteobacteria,42UXH@68525|delta/epsilon subdivisions,2WVP3@28221|Deltaproteobacteria,43SMM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver domain	cheY40H-4	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
LZS3_k127_6096304_2	1232410.KI421413_gene806	1.175e-71	266.0	COG2203@1|root,COG2203@2|Bacteria,1RJ35@1224|Proteobacteria,42T0K@68525|delta/epsilon subdivisions,2WPIM@28221|Deltaproteobacteria,43T60@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3
LZS3_k127_6096304_0	443143.GM18_3602	2.962e-99	351.0	COG2201@1|root,COG2201@2|Bacteria,1R5IM@1224|Proteobacteria,42Q4X@68525|delta/epsilon subdivisions,2WMDB@28221|Deltaproteobacteria,43T38@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB40H-1	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
LZS3_k127_6096304_1	243231.GSU2215	5.483e-85	295.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,43UG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
LZS3_k127_6096304_4	977880.RALTA_B2024	4.649e-05	48.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,2VQ82@28216|Betaproteobacteria,1KHI1@119060|Burkholderiaceae	28216|Betaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
LZS3_k127_6097260_1	404589.Anae109_0019	1.682e-13	75.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,42TD5@68525|delta/epsilon subdivisions,2WP3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF5011,HYR,OMP_b-brl,OmpA,TSP_3
LZS3_k127_6097260_0	195253.Syn6312_2738	1.747e-104	350.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1GYG1@1129|Synechococcus	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS3_k127_6099106_0	1232410.KI421415_gene3124	1.427e-177	582.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS domain	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
LZS3_k127_6099106_1	404380.Gbem_3286	4.388e-165	535.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6105102_5	1146883.BLASA_1986	1.56e-44	182.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4EUAJ@85013|Frankiales	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_6105102_3	1240349.ANGC01000013_gene525	3.119e-52	200.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4FWE4@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
LZS3_k127_6105102_4	469383.Cwoe_0838	9.919e-48	178.0	COG0491@1|root,COG0491@2|Bacteria,2HPJA@201174|Actinobacteria,4CQWR@84995|Rubrobacteria	84995|Rubrobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6105102_1	471852.Tcur_2583	4.264e-139	456.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
LZS3_k127_6105102_2	2002.JOEQ01000005_gene3373	1.457e-134	441.0	28KAT@1|root,2Z9XX@2|Bacteria,2GNVW@201174|Actinobacteria,4ENJ3@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6105102_8	873517.HMPREF1977_0096	0.0009763	52.0	COG3391@1|root,COG4935@1|root,COG3391@2|Bacteria,COG4935@2|Bacteria,4NEN7@976|Bacteroidetes,1HWMS@117743|Flavobacteriia,1ER48@1016|Capnocytophaga	976|Bacteroidetes	O	Thrombospondin type 3	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,P_proprotein,Reprolysin_4,TSP_3
LZS3_k127_6105102_0	946362.XP_004997743.1	1.378e-169	571.0	COG2132@1|root,2QR4X@2759|Eukaryota,38BK4@33154|Opisthokonta	33154|Opisthokonta	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
LZS3_k127_6105102_7	1192034.CAP_8119	2.697e-09	72.0	COG5184@1|root,COG5184@2|Bacteria,1QUHA@1224|Proteobacteria,42VF6@68525|delta/epsilon subdivisions,2WR7F@28221|Deltaproteobacteria,2YV9Z@29|Myxococcales	28221|Deltaproteobacteria	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
LZS3_k127_6106423_2	1047013.AQSP01000078_gene2052	3.312e-50	191.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans
LZS3_k127_6106423_1	67356.KL575644_gene1929	5.328e-74	260.0	COG3751@1|root,COG3751@2|Bacteria,2HN62@201174|Actinobacteria	201174|Actinobacteria	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
LZS3_k127_6106423_0	316057.RPD_2209	1.827e-146	477.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,3JQWG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	MA20_17095	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_6106423_3	118166.JH976537_gene4539	6.37e-14	86.0	COG2027@1|root,COG2027@2|Bacteria,1G06E@1117|Cyanobacteria,1H79I@1150|Oscillatoriales	1117|Cyanobacteria	M	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
LZS3_k127_6110977_0	1282876.BAOK01000002_gene695	3.089e-95	319.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	MA20_06735	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_6110977_1	215803.DB30_0854	9.02e-90	304.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2X1W0@28221|Deltaproteobacteria,2YUZR@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_6113559_2	1192034.CAP_4238	1.429e-33	148.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria,2YYYG@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_6113559_0	1333998.M2A_2401	1.001e-148	498.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TQRA@28211|Alphaproteobacteria,4BP67@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_6113559_1	85643.Tmz1t_1778	7.308e-115	377.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,2KU8H@206389|Rhodocyclales	206389|Rhodocyclales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
LZS3_k127_6135892_2	314285.KT71_04445	9.752e-14	75.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,1RNQR@1236|Gammaproteobacteria,1J861@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Alpha/beta hydrolase family	ynbC	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Methyltransf_20
LZS3_k127_6135892_0	264732.Moth_2134	1.927e-43	169.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,42GMY@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
LZS3_k127_6135892_1	215803.DB30_0034	1.155e-32	136.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YWN4@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_6135892_3	981383.AEWH01000075_gene3806	2.765e-05	55.0	COG5662@1|root,COG5662@2|Bacteria,1V6C7@1239|Firmicutes,4HFTK@91061|Bacilli	91061|Bacilli	K	anti-sigma factor	rsiW	GO:0005575,GO:0016020	-	-	-	-	-	-	-	-	-	-	Bactofilin,zf-HC2
LZS3_k127_6138948_1	667014.Thein_0885	5.088e-31	125.0	COG0261@1|root,COG0261@2|Bacteria,2GHY6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
LZS3_k127_6138948_2	1307759.JOMJ01000003_gene1096	4.355e-28	122.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2MCGT@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
LZS3_k127_6138948_0	935261.JAGL01000021_gene463	5.645e-102	345.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,43IS4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
LZS3_k127_6142541_0	1245475.ANAE01000182_gene1035	2.935e-74	267.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria,4EFZS@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_6142541_1	330214.NIDE0386	8.894e-65	234.0	COG2377@1|root,COG2377@2|Bacteria,3J126@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
LZS3_k127_6168403_0	1329516.JPST01000019_gene2688	1.38e-87	305.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,27BB2@186824|Thermoactinomycetaceae	91061|Bacilli	I	Thiolase, C-terminal domain	pcaF	-	2.3.1.174,2.3.1.223,2.3.1.9	ko:K00626,ko:K02615	ko00071,ko00072,ko00280,ko00310,ko00360,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00360,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R00829,R01177,R09839	RC00004,RC00326,RC03003	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_6168403_1	383372.Rcas_4359	5.211e-21	95.0	COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi,376BW@32061|Chloroflexia	32061|Chloroflexia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_6173758_0	886293.Sinac_2608	4.079e-108	382.0	COG0075@1|root,COG0075@2|Bacteria,2IYEK@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
LZS3_k127_6173758_1	381666.H16_A3433	1.251e-97	353.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,1K15K@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
LZS3_k127_6173758_2	290397.Adeh_1133	9.912e-32	128.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
LZS3_k127_617776_1	443143.GM18_3946	1.425e-57	213.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,43W1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_617776_3	1232410.KI421425_gene1566	2.154e-36	148.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2X7M4@28221|Deltaproteobacteria,43VY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_617776_0	1380386.JIAW01000025_gene6827	3.349e-154	499.0	COG0183@1|root,COG0183@2|Bacteria,2IDAP@201174|Actinobacteria,233A4@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_617776_2	316274.Haur_0959	5.481e-48	181.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_617799_0	1242864.D187_009298	5.116e-51	190.0	COG0637@1|root,COG0637@2|Bacteria,1QX9J@1224|Proteobacteria,43C2S@68525|delta/epsilon subdivisions,2X7DC@28221|Deltaproteobacteria,2Z3FR@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD
LZS3_k127_617799_2	29581.BW37_03134	7.749e-06	58.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria	28216|Betaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
LZS3_k127_617799_1	65093.PCC7418_2903	1.478e-10	74.0	COG3049@1|root,COG3049@2|Bacteria,1GCTV@1117|Cyanobacteria	1117|Cyanobacteria	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
LZS3_k127_6185262_1	1125863.JAFN01000001_gene683	1.423e-50	194.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase, family 39	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_6185262_0	383372.Rcas_2618	1.384e-159	522.0	COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi,376KP@32061|Chloroflexia	32061|Chloroflexia	G	PFAM Xylose isomerase domain protein TIM barrel	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
LZS3_k127_6185410_2	1121920.AUAU01000033_gene2765	2.291e-52	210.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,3Y6AK@57723|Acidobacteria	57723|Acidobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS3_k127_6185410_3	1499967.BAYZ01000080_gene894	4.921e-19	102.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
LZS3_k127_6185410_1	1282876.BAOK01000001_gene2836	2.802e-89	311.0	COG4943@1|root,COG4943@2|Bacteria,1QZSA@1224|Proteobacteria,2TYDN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
LZS3_k127_6185410_0	1268068.PG5_34260	2.49e-95	319.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1RY5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_6212605_3	243231.GSU2224	2.18e-31	136.0	COG0745@1|root,COG0745@2|Bacteria,1N9YT@1224|Proteobacteria,42W15@68525|delta/epsilon subdivisions,2WS2V@28221|Deltaproteobacteria,43T56@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	regulator, PATAN and FRGAF domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
LZS3_k127_6212605_2	243231.GSU2223	3.273e-33	146.0	COG0745@1|root,COG0745@2|Bacteria,1N1TA@1224|Proteobacteria,42V03@68525|delta/epsilon subdivisions,2WPZR@28221|Deltaproteobacteria,43V4S@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	cheY40H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
LZS3_k127_6212605_0	398767.Glov_2123	9.491e-165	554.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,43S5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
LZS3_k127_6212605_4	635013.TherJR_0110	1.933e-20	108.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,2623N@186807|Peptococcaceae	186801|Clostridia	NT	PFAM CheW domain protein	CheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS3_k127_6212605_5	1121423.JONT01000006_gene2474	6.068e-17	89.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,261WX@186807|Peptococcaceae	186801|Clostridia	NT	Chemotaxis signal transduction protein	CheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS3_k127_6212605_1	290397.Adeh_0058	1.616e-66	258.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
LZS3_k127_6212605_6	338963.Pcar_2546	1.254e-08	58.0	2AKQ6@1|root,31BGX@2|Bacteria,1RCS3@1224|Proteobacteria,43CF4@68525|delta/epsilon subdivisions,2WP3G@28221|Deltaproteobacteria,43SKD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4
LZS3_k127_6218221_0	330214.NIDE1585	2.97e-121	404.0	COG2204@1|root,COG2204@2|Bacteria,3J0C2@40117|Nitrospirae	2|Bacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6229894_0	1205680.CAKO01000037_gene1298	9.291e-237	740.0	COG0439@1|root,COG1038@1|root,COG4799@1|root,COG0439@2|Bacteria,COG1038@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2TWYZ@28211|Alphaproteobacteria,2JZ2C@204441|Rhodospirillales	204441|Rhodospirillales	I	Biotin carboxylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
LZS3_k127_6250885_2	1280946.HY29_16265	1.306e-06	62.0	COG1960@1|root,COG1960@2|Bacteria,1R7HF@1224|Proteobacteria,2U3BJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_6250885_1	478741.JAFS01000001_gene2211	5.282e-81	274.0	COG1225@1|root,COG1225@2|Bacteria,46SWU@74201|Verrucomicrobia,37GJJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
LZS3_k127_6250885_0	1123368.AUIS01000026_gene1471	2.846e-228	716.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,2NCBF@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
LZS3_k127_6268124_0	378806.STAUR_6435	6.644e-50	203.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
LZS3_k127_6268124_1	502025.Hoch_0255	1.433e-49	183.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria,2YVRN@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
LZS3_k127_6268124_2	443143.GM18_1393	7.391e-13	79.0	COG2018@1|root,COG2018@2|Bacteria,1NG1T@1224|Proteobacteria,42VP4@68525|delta/epsilon subdivisions,2WS9A@28221|Deltaproteobacteria,43V7Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6268124_3	398767.Glov_1593	1.672e-05	54.0	COG4783@1|root,COG4783@2|Bacteria,1QZ64@1224|Proteobacteria,43CH3@68525|delta/epsilon subdivisions,2X7SA@28221|Deltaproteobacteria,43VYR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6270075_2	1122609.AUGT01000011_gene3568	2.18e-15	78.0	COG0526@1|root,COG0526@2|Bacteria,2HZTZ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_6270075_0	861299.J421_2862	1.598e-254	792.0	COG0499@1|root,COG0499@2|Bacteria,1ZTEF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS3_k127_6270075_1	1121937.AUHJ01000001_gene813	7.783e-103	353.0	COG0451@1|root,COG0451@2|Bacteria,1RGHF@1224|Proteobacteria,1RQTC@1236|Gammaproteobacteria,4696K@72275|Alteromonadaceae	1236|Gammaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_6270772_1	335543.Sfum_1753	7.85e-57	214.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria,2MRB3@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transport system involved in gliding motility auxiliary component-like	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
LZS3_k127_6270772_3	1382359.JIAL01000001_gene1268	9.228e-37	158.0	COG1277@1|root,COG1277@2|Bacteria,3Y6D0@57723|Acidobacteria	57723|Acidobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
LZS3_k127_6270772_0	1125863.JAFN01000001_gene2142	1.066e-71	263.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_6270772_2	215803.DB30_0318	2.241e-44	169.0	COG1309@1|root,COG1309@2|Bacteria,1NQ0S@1224|Proteobacteria,43AGR@68525|delta/epsilon subdivisions,2WN8X@28221|Deltaproteobacteria,2YX94@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K13770	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_4,TetR_N
LZS3_k127_6285571_0	928724.SacglDRAFT_02786	9.707e-74	258.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4DX4D@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
LZS3_k127_6285571_2	1227739.Hsw_PA0081	0.0001071	54.0	COG0477@1|root,COG2814@2|Bacteria,4PMD0@976|Bacteroidetes,47V52@768503|Cytophagia	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_6285571_1	649638.Trad_0291	6.982e-07	56.0	COG1983@1|root,COG1983@2|Bacteria,1WKSH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
LZS3_k127_6285571_3	298655.KI912266_gene5090	0.0002316	45.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_6293280_1	522373.Smlt1680	1.009e-20	98.0	COG3832@1|root,COG3832@2|Bacteria,1REDB@1224|Proteobacteria,1S3Z4@1236|Gammaproteobacteria,1XDA6@135614|Xanthomonadales	135614|Xanthomonadales	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
LZS3_k127_6293280_2	396588.Tgr7_3066	4.523e-18	91.0	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,1SCNZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	DnaK suppressor protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
LZS3_k127_6293280_0	408672.NBCG_00750	2.374e-88	299.0	COG1236@1|root,COG1236@2|Bacteria,2HEXB@201174|Actinobacteria,4DQ4R@85009|Propionibacteriales	201174|Actinobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL
LZS3_k127_6298514_7	1316936.K678_12030	9.085e-08	64.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2TTBW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
LZS3_k127_6298514_5	935839.JAGJ01000003_gene1438	7.973e-19	100.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4F42F@85017|Promicromonosporaceae	201174|Actinobacteria	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA,Wzz
LZS3_k127_6298514_2	1123073.KB899241_gene2322	1.464e-64	234.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1X4ZI@135614|Xanthomonadales	135614|Xanthomonadales	U	AAA domain	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
LZS3_k127_6298514_4	1122185.N792_09625	8.485e-23	107.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,1S35N@1236|Gammaproteobacteria,1X60X@135614|Xanthomonadales	135614|Xanthomonadales	M	Sugar ABC transporter substrate-binding protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
LZS3_k127_6298514_6	378806.STAUR_2817	1.013e-16	83.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,431UR@68525|delta/epsilon subdivisions,2WWZQ@28221|Deltaproteobacteria,2YU65@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
LZS3_k127_6298514_1	246197.MXAN_2064	1.092e-78	271.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42T24@68525|delta/epsilon subdivisions,2WPF8@28221|Deltaproteobacteria,2YV09@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
LZS3_k127_6298514_3	1232437.KL662001_gene4572	1.366e-39	160.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIX8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07714,ko:K07715	ko02020,ko02024,map02020,map02024	M00500,M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6298514_0	84531.JMTZ01000034_gene378	3.94e-93	317.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1X4XY@135614|Xanthomonadales	135614|Xanthomonadales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
LZS3_k127_6300819_0	264462.Bd3432	4.912e-150	495.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2MSND@213481|Bdellovibrionales,2WIT0@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	two component, sigma54 specific, transcriptional regulator, Fis family	fgrM	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6300819_1	404589.Anae109_4152	1.522e-111	377.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YX5F@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	nla19	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6337145_0	1254432.SCE1572_18520	4.076e-90	302.0	COG2267@1|root,COG2267@2|Bacteria,1QZUV@1224|Proteobacteria	1224|Proteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6337145_1	89187.ISM_11615	1.619e-17	90.0	COG0818@1|root,COG0818@2|Bacteria,1Q2K5@1224|Proteobacteria,2UIPU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
LZS3_k127_6337145_2	1245471.PCA10_43640	1.277e-06	56.0	COG1028@1|root,COG1028@2|Bacteria,1PHKF@1224|Proteobacteria,1RX6C@1236|Gammaproteobacteria,1YHY0@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_6341343_5	1380394.JADL01000018_gene1896	1.579e-56	218.0	2EX4W@1|root,33QFX@2|Bacteria,1NRWJ@1224|Proteobacteria,2UNPH@28211|Alphaproteobacteria,2JVSM@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6341343_13	1288298.rosmuc_00275	8.556e-06	57.0	COG2755@1|root,COG2755@2|Bacteria,1RBUM@1224|Proteobacteria,2URAI@28211|Alphaproteobacteria,46RMZ@74030|Roseovarius	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6341343_3	439235.Dalk_0906	3.751e-119	403.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,42NCG@68525|delta/epsilon subdivisions,2WK7N@28221|Deltaproteobacteria,2MIZV@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	-	-	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
LZS3_k127_6341343_4	1121403.AUCV01000004_gene2046	1.065e-100	344.0	COG4775@1|root,COG4775@2|Bacteria,1RDM0@1224|Proteobacteria,42S2Q@68525|delta/epsilon subdivisions,2WNSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
LZS3_k127_6341343_9	697282.Mettu_2351	2.159e-22	101.0	2DP6U@1|root,330T2@2|Bacteria,1N7R9@1224|Proteobacteria,1SDI8@1236|Gammaproteobacteria,1XFBA@135618|Methylococcales	135618|Methylococcales	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
LZS3_k127_6341343_6	398767.Glov_2394	1.516e-50	196.0	COG3203@1|root,COG3203@2|Bacteria,1RIIY@1224|Proteobacteria,430MU@68525|delta/epsilon subdivisions,2WVSM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6341343_0	234267.Acid_5793	6.077e-190	610.0	COG1757@1|root,COG1757@2|Bacteria	2|Bacteria	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
LZS3_k127_6341343_2	1380355.JNIJ01000001_gene3927	2.608e-152	520.0	COG0651@1|root,COG0651@2|Bacteria,1N6BY@1224|Proteobacteria,2TUZY@28211|Alphaproteobacteria,3JXRH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
LZS3_k127_6341343_1	395965.Msil_1037	1.57e-173	563.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria,3NCZI@45404|Beijerinckiaceae	28211|Alphaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
LZS3_k127_6341343_8	395965.Msil_1036	1.58e-34	138.0	COG1006@1|root,COG1006@2|Bacteria,1N7TX@1224|Proteobacteria,2UHUU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	PFAM NADH-ubiquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
LZS3_k127_6341343_10	622637.KE124774_gene2188	6.743e-13	69.0	COG2111@1|root,COG2111@2|Bacteria,1QVK4@1224|Proteobacteria,2TWGZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Domain of unknown function (DUF4040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040,MnhB
LZS3_k127_6344125_0	243233.MCA1944	3.708e-104	364.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RM9E@1236|Gammaproteobacteria,1XGYY@135618|Methylococcales	135618|Methylococcales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
LZS3_k127_6344125_1	1284352.AOIG01000028_gene616	3.335e-90	312.0	COG3459@1|root,COG3459@2|Bacteria	2|Bacteria	G	carbohydrate binding	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	DUF3131,Glyco_hydro_36,Glyco_transf_36,Glycoamylase
LZS3_k127_6356891_1	710111.FraQA3DRAFT_5921	1.279e-37	153.0	COG2365@1|root,COG2365@2|Bacteria,2GK28@201174|Actinobacteria,4EVXB@85013|Frankiales	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
LZS3_k127_6356891_0	1499967.BAYZ01000194_gene3127	1.23e-62	229.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
LZS3_k127_6356891_2	1254432.SCE1572_10850	2.27e-24	104.0	COG0372@1|root,COG0789@1|root,COG0372@2|Bacteria,COG0789@2|Bacteria,1MXFW@1224|Proteobacteria,43B14@68525|delta/epsilon subdivisions,2X6FA@28221|Deltaproteobacteria,2YX0F@29|Myxococcales	28221|Deltaproteobacteria	C	Helix-turn-helix domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
LZS3_k127_6363151_0	545276.KB898736_gene1268	2.359e-178	593.0	COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,1RZXX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,PDDEXK_1,RNase_H_2
LZS3_k127_6363151_1	379066.GAU_3626	3.651e-31	124.0	COG1538@1|root,COG1538@2|Bacteria,1ZUIP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_636545_0	66875.JODY01000006_gene2209	2.336e-123	415.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	amiC_1	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
LZS3_k127_6387041_2	880072.Desac_0168	6.949e-36	143.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2MS32@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS3_k127_6387041_1	391625.PPSIR1_30893	1.196e-37	161.0	COG0560@1|root,COG0560@2|Bacteria,1MWTU@1224|Proteobacteria,43BHJ@68525|delta/epsilon subdivisions,2X6W0@28221|Deltaproteobacteria,2Z3D8@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
LZS3_k127_6387041_0	443144.GM21_1758	1.641e-100	340.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,43TZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
LZS3_k127_6387570_0	78245.Xaut_1004	1.074e-163	535.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2TSPJ@28211|Alphaproteobacteria,3F1GM@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	PFAM phenylalanine histidine ammonia-lyase	hutH	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009698,GO:0009699,GO:0009987,GO:0016043,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044550,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052883,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
LZS3_k127_6387570_1	391625.PPSIR1_04478	1.377e-21	98.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,42V26@68525|delta/epsilon subdivisions,2WQ0Y@28221|Deltaproteobacteria,2Z2KY@29|Myxococcales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS3_k127_6387570_2	640512.BC1003_2659	1.591e-11	71.0	COG0236@1|root,COG0236@2|Bacteria,1N7Q1@1224|Proteobacteria,2VVRR@28216|Betaproteobacteria,1K9MR@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpM	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS3_k127_6400353_2	62928.azo2142	2.947e-18	96.0	COG2905@1|root,COG2905@2|Bacteria,1N7MU@1224|Proteobacteria,2VVGU@28216|Betaproteobacteria,2KZVZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_6400353_4	448385.sce6562	1.942e-10	73.0	2AN96@1|root,31D78@2|Bacteria,1QAAX@1224|Proteobacteria,434Y2@68525|delta/epsilon subdivisions,2WZ8X@28221|Deltaproteobacteria,2Z1KT@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
LZS3_k127_6400353_0	1303518.CCALI_01155	3.64e-119	392.0	COG1064@1|root,COG1064@2|Bacteria	2|Bacteria	P	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_6400353_3	1463936.JOJI01000006_gene4283	9.335e-17	90.0	COG0546@1|root,COG0546@2|Bacteria,2I9X5@201174|Actinobacteria	201174|Actinobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAD
LZS3_k127_6400353_1	412597.AEPN01000004_gene3171	2.519e-40	168.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,2PV48@265|Paracoccus	28211|Alphaproteobacteria	O	Scaffold protein Nfu/NifU N terminal	nifU	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
LZS3_k127_6415363_1	215803.DB30_2905	3.092e-25	113.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
LZS3_k127_6415363_0	706587.Desti_3193	7.05e-34	138.0	2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria,42ZVK@68525|delta/epsilon subdivisions,2WV6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	-	-	1.21.4.1	ko:K10794	ko00330,map00330	-	R02825	RC00790	ko00000,ko00001,ko01000	-	-	-	GRDB
LZS3_k127_641621_0	483219.LILAB_02345	3.444e-152	505.0	COG2170@1|root,COG2170@2|Bacteria,1MXET@1224|Proteobacteria,43BYB@68525|delta/epsilon subdivisions,2X798@28221|Deltaproteobacteria,2YX02@29|Myxococcales	28221|Deltaproteobacteria	S	glutamate--cysteine ligase	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
LZS3_k127_641621_1	1283299.AUKG01000002_gene4966	5.408e-57	208.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_642030_0	290397.Adeh_0078	1.421e-31	139.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_642030_1	335541.Swol_0642	1.645e-26	118.0	COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,24IHI@186801|Clostridia,42KRZ@68298|Syntrophomonadaceae	186801|Clostridia	E	Putative Phosphatase	mtnX	-	-	-	-	-	-	-	-	-	-	-	HAD,Put_Phosphatase
LZS3_k127_6434201_0	443143.GM18_3369	1.17e-112	371.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6438271_1	580332.Slit_2920	2.645e-112	368.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,44VJP@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
LZS3_k127_6438271_0	330214.NIDE1084	4.269e-125	416.0	COG0577@1|root,COG0577@2|Bacteria,3J0EW@40117|Nitrospirae	40117|Nitrospirae	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_6438271_2	671143.DAMO_3154	5.342e-19	88.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_6441229_2	1280946.HY29_07010	5e-17	96.0	COG1309@1|root,COG1309@2|Bacteria,1N208@1224|Proteobacteria,2UDE9@28211|Alphaproteobacteria,43ZPV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_6441229_0	1168065.DOK_13194	1.851e-137	451.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria,1RQYQ@1236|Gammaproteobacteria,1J5B4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_6441229_1	1192034.CAP_4257	7.998e-77	263.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2YU21@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
LZS3_k127_6457093_0	67267.JNXT01000011_gene975	1.14e-31	127.0	COG0526@1|root,COG0526@2|Bacteria,2HZTZ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_6457093_1	479433.Caci_0867	9.205e-25	108.0	COG0526@1|root,COG0526@2|Bacteria,2HZTZ@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_6457093_2	1469613.JT55_01685	5.696e-22	104.0	2DPFX@1|root,331WC@2|Bacteria,1NEA1@1224|Proteobacteria,2UIWR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6476509_2	1411123.JQNH01000001_gene1061	3.741e-28	122.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
LZS3_k127_6476509_1	290398.Csal_2676	2.956e-59	212.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,1XJ75@135619|Oceanospirillales	135619|Oceanospirillales	P	(ABC) transporter	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
LZS3_k127_6476509_0	1525715.IX54_02225	1.315e-63	245.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,2PUIK@265|Paracoccus	28211|Alphaproteobacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
LZS3_k127_6476509_3	550540.Fbal_3382	8.232e-20	91.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Transglycosylase-associated protein	yeaQ	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
LZS3_k127_6549307_6	575540.Isop_2077	1.641e-07	56.0	COG1641@1|root,COG1641@2|Bacteria,2IXMJ@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
LZS3_k127_6549307_1	404380.Gbem_3625	7.774e-76	261.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
LZS3_k127_6549307_5	697284.ERIC2_c21440	3.728e-18	100.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,4HB40@91061|Bacilli,26TGH@186822|Paenibacillaceae	91061|Bacilli	NT	chemotaxis protein	cheC	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC,CheX
LZS3_k127_6549307_0	404589.Anae109_4461	5.18e-78	286.0	COG0643@1|root,COG0643@2|Bacteria,1NW7P@1224|Proteobacteria,42PGY@68525|delta/epsilon subdivisions,2WM89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	difE	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
LZS3_k127_6549307_4	243231.GSU3199	4.263e-22	100.0	COG0643@1|root,COG0643@2|Bacteria,1NW7P@1224|Proteobacteria,42PGY@68525|delta/epsilon subdivisions,2WM89@28221|Deltaproteobacteria,43T85@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	difE	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
LZS3_k127_6549307_3	771875.Ferpe_0479	7.981e-36	150.0	COG2201@1|root,COG2201@2|Bacteria,2GCZV@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
LZS3_k127_6549307_7	1219084.AP014508_gene701	0.0004912	51.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	cheW2	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
LZS3_k127_6549307_2	243231.GSU3196	1.176e-61	229.0	COG0840@1|root,COG0840@2|Bacteria,1RA20@1224|Proteobacteria,42QNV@68525|delta/epsilon subdivisions,2WMT1@28221|Deltaproteobacteria,43T7D@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
LZS3_k127_6579440_2	985054.JQEZ01000001_gene2494	0.000316	44.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,2TQXY@28211|Alphaproteobacteria,4NDRU@97050|Ruegeria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
LZS3_k127_6579440_1	631454.N177_2840	4.122e-08	63.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,2U93G@28211|Alphaproteobacteria,1JPFZ@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
LZS3_k127_6579440_0	326424.FRAAL3740	1.719e-143	466.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria	201174|Actinobacteria	K	epoxide hydrolase	-	-	3.3.2.9	ko:K01253	ko00980,ko04976,ko05204,map00980,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
LZS3_k127_6614623_0	1254432.SCE1572_01860	3.263e-267	856.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R66T@1224|Proteobacteria	1224|Proteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6623815_3	1479237.JMLY01000001_gene538	4.739e-69	237.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,1RRN8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	ygcU	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS3_k127_6623815_2	402881.Plav_2677	2.831e-101	346.0	COG5285@1|root,COG5285@2|Bacteria,1QRDD@1224|Proteobacteria,2U0EC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS3_k127_6623815_1	1125863.JAFN01000001_gene2316	1.107e-167	536.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_6623815_4	1323663.AROI01000002_gene1227	8.478e-51	185.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,1RSMY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
LZS3_k127_6623815_0	395493.BegalDRAFT_0585	7.696e-249	782.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,45ZW1@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
LZS3_k127_6623815_5	234267.Acid_7234	1.042e-15	89.0	COG0457@1|root,COG0457@2|Bacteria,3Y5ID@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6625095_0	667014.Thein_1300	2.243e-152	498.0	COG0165@1|root,COG0165@2|Bacteria,2GGV2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
LZS3_k127_6625095_2	1122951.ATUE01000005_gene1760	3.503e-77	277.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,3NIIS@468|Moraxellaceae	1236|Gammaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
LZS3_k127_6625095_1	1125863.JAFN01000001_gene2756	2.112e-100	352.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS3_k127_6639542_2	1089455.MOPEL_135_00950	2.315e-17	86.0	COG0644@1|root,COG0644@2|Bacteria,2GM2M@201174|Actinobacteria	201174|Actinobacteria	C	FAD dependent oxidoreductase	srsC	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
LZS3_k127_6639542_1	234267.Acid_1354	9.346e-33	144.0	COG2353@1|root,COG2353@2|Bacteria,3Y5DX@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
LZS3_k127_6639542_0	398580.Dshi_3401	1.985e-75	262.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
LZS3_k127_6639756_1	68223.JNZY01000049_gene3450	8.282e-22	108.0	COG0789@1|root,COG0789@2|Bacteria,2GKSZ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
LZS3_k127_6639756_0	479432.Sros_6142	4.61e-60	215.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EHHD@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_6647745_0	290397.Adeh_2009	9.165e-111	372.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
LZS3_k127_6647745_1	1144275.COCOR_04880	7.308e-91	308.0	COG1801@1|root,COG1801@2|Bacteria,1MXIQ@1224|Proteobacteria,42XHB@68525|delta/epsilon subdivisions,2WSKY@28221|Deltaproteobacteria,2YVC2@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS3_k127_6669152_0	62928.azo1687	9.006e-177	571.0	COG0744@1|root,COG0744@2|Bacteria,1NRPB@1224|Proteobacteria,2VJ7F@28216|Betaproteobacteria,2KVVR@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0744 Membrane carboxypeptidase (penicillin-binding protein)	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
LZS3_k127_6683790_2	682795.AciX8_3879	7.691e-07	62.0	COG0707@1|root,COG0707@2|Bacteria,3Y48B@57723|Acidobacteria,2JIYA@204432|Acidobacteriia	204432|Acidobacteriia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
LZS3_k127_6683790_0	1121918.ARWE01000001_gene872	1.232e-56	215.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,43TAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
LZS3_k127_6683790_1	1304275.C41B8_04716	1.147e-19	90.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097	Mur_ligase_C,Mur_ligase_M
LZS3_k127_6692639_3	1278073.MYSTI_05802	4.299e-54	195.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
LZS3_k127_6692639_1	1254432.SCE1572_09510	2.195e-204	644.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
LZS3_k127_6692639_0	469383.Cwoe_4211	2.603e-285	889.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4CQXA@84995|Rubrobacteria	84995|Rubrobacteria	C	Phosphoenolpyruvate carboxykinase C-terminal P-loop domain	-	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
LZS3_k127_6692639_4	1123256.KB907942_gene39	3.286e-40	168.0	COG0346@1|root,COG0346@2|Bacteria,1N1D4@1224|Proteobacteria,1S7IY@1236|Gammaproteobacteria,1X7V3@135614|Xanthomonadales	135614|Xanthomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_6692639_2	1265313.HRUBRA_00422	1.469e-108	363.0	COG0604@1|root,COG0604@2|Bacteria,1QUNT@1224|Proteobacteria,1T25R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
LZS3_k127_669674_0	745014.OMB55_00019940	1.157e-127	446.0	COG3391@1|root,COG3391@2|Bacteria,1R66T@1224|Proteobacteria	1224|Proteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
LZS3_k127_669674_1	1121920.AUAU01000018_gene1786	1.959e-51	192.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
LZS3_k127_669674_3	633149.Bresu_0564	9.979e-06	60.0	COG1309@1|root,COG1309@2|Bacteria,1PA7Z@1224|Proteobacteria,2UUB8@28211|Alphaproteobacteria,2KHD3@204458|Caulobacterales	204458|Caulobacterales	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_669674_2	319003.Bra1253DRAFT_06628	4.952e-30	134.0	COG0457@1|root,COG3710@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2U2S9@28211|Alphaproteobacteria,3JX6E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Trans_reg_C
LZS3_k127_6699466_5	330214.NIDE1146	5.687e-29	129.0	COG1249@1|root,COG1249@2|Bacteria,3J0IM@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS3_k127_6699466_4	317619.ANKN01000172_gene1147	1.385e-49	184.0	COG0398@1|root,COG0398@2|Bacteria,1GC4B@1117|Cyanobacteria,1MMHD@1212|Prochloraceae	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS3_k127_6699466_3	471852.Tcur_3579	3.117e-59	227.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4EGF3@85012|Streptosporangiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
LZS3_k127_6699466_0	1205680.CAKO01000002_gene2850	3.965e-146	473.0	COG1633@1|root,COG1633@2|Bacteria,1R02H@1224|Proteobacteria,2TYHQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
LZS3_k127_6699466_1	402881.Plav_1544	1.102e-117	392.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TU15@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome P-450	-	-	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_6699466_2	886293.Sinac_0922	1.58e-76	283.0	COG2271@1|root,COG2271@2|Bacteria,2IYNX@203682|Planctomycetes	203682|Planctomycetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_6701068_0	309801.trd_A0275	1.307e-98	343.0	COG1351@1|root,COG1351@2|Bacteria,2G9ZK@200795|Chloroflexi,27XV1@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
LZS3_k127_6713844_4	671143.DAMO_2979	9.494e-40	161.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF616,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_2,Glyphos_transf,NTP_transf_5
LZS3_k127_6713844_3	671143.DAMO_2980	4.488e-60	231.0	COG1216@1|root,COG1216@2|Bacteria,2NP6P@2323|unclassified Bacteria	2|Bacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6713844_1	1541065.JRFE01000014_gene1221	2.116e-66	251.0	COG0438@1|root,COG0438@2|Bacteria,1GIUV@1117|Cyanobacteria,3VKMD@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
LZS3_k127_6713844_2	671143.DAMO_2981	3.63e-66	239.0	COG1493@1|root,COG1493@2|Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
LZS3_k127_6713844_7	195253.Syn6312_2320	9.335e-21	103.0	2DRDY@1|root,33BC0@2|Bacteria	2|Bacteria	S	PFAM Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
LZS3_k127_6713844_0	671143.DAMO_2983	2.459e-98	333.0	COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	2.4.1.11,2.4.1.345	ko:K08256,ko:K16150	ko00500,ko01100,map00500,map01100	-	R00292,R11702	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_6713844_6	62928.azo3253	3.169e-26	123.0	COG0438@1|root,COG0438@2|Bacteria,1PVZ8@1224|Proteobacteria,2VPK3@28216|Betaproteobacteria,2KXQZ@206389|Rhodocyclales	206389|Rhodocyclales	M	COG0438 Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6713844_5	1121406.JAEX01000016_gene1873	1.21e-27	131.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_3_5,Polysacc_deac_1
LZS3_k127_6715729_2	414684.RC1_1548	4.873e-51	199.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TRD3@28211|Alphaproteobacteria,2JPVK@204441|Rhodospirillales	204441|Rhodospirillales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS3_k127_6715729_3	1123256.KB907925_gene1293	7.325e-38	149.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1T07B@1236|Gammaproteobacteria,1X8T2@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1255
LZS3_k127_6715729_4	1479238.JQMZ01000001_gene1301	6.607e-32	141.0	COG3591@1|root,COG3591@2|Bacteria,1NQI1@1224|Proteobacteria,2U5SD@28211|Alphaproteobacteria,43XDT@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6715729_6	439235.Dalk_2007	1.049e-20	104.0	COG2755@1|root,COG2755@2|Bacteria,1NJHS@1224|Proteobacteria,42Y0B@68525|delta/epsilon subdivisions,2WTGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6715729_0	479434.Sthe_1507	2.547e-106	360.0	COG0477@1|root,COG2814@2|Bacteria,2G8DX@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_6715729_5	278963.ATWD01000001_gene3833	2.138e-28	120.0	COG0251@1|root,COG0251@2|Bacteria,3Y57T@57723|Acidobacteria,2JJQ3@204432|Acidobacteriia	204432|Acidobacteriia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
LZS3_k127_6715729_1	1160137.KB907307_gene2345	1.694e-53	194.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_6718425_1	13035.Dacsa_3537	1.843e-95	351.0	COG0438@1|root,COG0438@2|Bacteria,1G1J6@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	sqdX	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_6718425_2	1071085.KK033114_gene799	3.019e-80	299.0	COG0154@1|root,arCOG01717@2157|Archaea,2XT5W@28890|Euryarchaeota,23S2Y@183963|Halobacteria	183963|Halobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
LZS3_k127_6718425_3	1385935.N836_09745	8.972e-79	290.0	COG2816@1|root,COG2816@2|Bacteria,1G3EM@1117|Cyanobacteria	1117|Cyanobacteria	L	Belongs to the Nudix hydrolase family. NudC subfamily	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
LZS3_k127_6718425_0	953739.SVEN_0524	1.658e-103	377.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipP	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_6718425_5	240015.ACP_0207	5.098e-36	155.0	COG1765@1|root,COG1765@2|Bacteria,3Y7VV@57723|Acidobacteria,2JN4F@204432|Acidobacteriia	204432|Acidobacteriia	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
LZS3_k127_6718425_4	649638.Trad_2090	1.39e-65	239.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_6721333_1	397278.JOJN01000003_gene1816	8.177e-24	108.0	COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria,4DRP0@85009|Propionibacteriales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
LZS3_k127_6721333_2	572477.Alvin_0423	2.349e-09	70.0	COG0674@1|root,COG0674@2|Bacteria,1QVAZ@1224|Proteobacteria,1S0VA@1236|Gammaproteobacteria,1WVZZ@135613|Chromatiales	135613|Chromatiales	C	pyruvate-flavodoxin oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6721333_0	1304885.AUEY01000007_gene1329	9.159e-68	254.0	COG0467@1|root,COG0467@2|Bacteria,1RFBT@1224|Proteobacteria,42QWP@68525|delta/epsilon subdivisions,2WMB2@28221|Deltaproteobacteria,2MISH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6725450_1	1121403.AUCV01000030_gene2741	2.618e-90	308.0	COG2340@1|root,COG2340@2|Bacteria,1RCX9@1224|Proteobacteria,42Z5E@68525|delta/epsilon subdivisions,2WUJM@28221|Deltaproteobacteria,2MN5A@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6725450_0	1121930.AQXG01000001_gene1141	1.388e-162	524.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1IPKZ@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_6727164_1	292459.STH604	2.918e-38	147.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,247KZ@186801|Clostridia	186801|Clostridia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
LZS3_k127_6727164_0	247633.GP2143_09450	6.292e-131	434.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,1RR6Y@1236|Gammaproteobacteria,1J7P2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2124 Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_6727899_0	384765.SIAM614_07448	3.345e-44	181.0	COG3420@1|root,COG3420@2|Bacteria,1RM1G@1224|Proteobacteria,2VGVG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
LZS3_k127_6729485_0	56780.SYN_00558	5.036e-161	525.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2MQAG@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
LZS3_k127_6729485_1	1254432.SCE1572_22705	4.085e-45	186.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2YUWH@29|Myxococcales	28221|Deltaproteobacteria	L	TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
LZS3_k127_6737458_0	404380.Gbem_3713	6.313e-202	637.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,43T9E@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
LZS3_k127_6737458_2	644966.Tmar_0155	6.275e-120	396.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WCCP@538999|Clostridiales incertae sedis	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS3_k127_6737458_3	706587.Desti_3951	1.01e-63	244.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2MQKB@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
LZS3_k127_6737458_1	1341151.ASZU01000008_gene1597	2.426e-121	413.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,27B6V@186824|Thermoactinomycetaceae	91061|Bacilli	E	Histidinol dehydrogenase	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU34910	Histidinol_dh
LZS3_k127_6737458_4	1238182.C882_3261	6.717e-60	230.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,2JPDI@204441|Rhodospirillales	204441|Rhodospirillales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
LZS3_k127_6737458_5	1121472.AQWN01000002_gene2274	5.243e-55	207.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,260M0@186807|Peptococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS3_k127_6737458_7	667014.Thein_1211	1.69e-11	76.0	2E6CS@1|root,3310E@2|Bacteria,2GH18@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6737458_6	195250.CM001776_gene1037	2.018e-23	115.0	COG0106@1|root,COG0106@2|Bacteria,1G1S9@1117|Cyanobacteria,1GYXA@1129|Synechococcus	1117|Cyanobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS3_k127_6740527_0	335543.Sfum_3567	1.494e-76	280.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,2MSID@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS3_k127_6748354_1	338966.Ppro_0966	7.345e-64	229.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,43UI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
LZS3_k127_6748354_2	76114.ebA5842	1.399e-15	86.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,2KWPI@206389|Rhodocyclales	206389|Rhodocyclales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
LZS3_k127_6748354_3	867845.KI911784_gene1347	2.15e-14	85.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi,375YB@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
LZS3_k127_6748354_0	1125863.JAFN01000001_gene1429	1.546e-209	670.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
LZS3_k127_6766617_2	1292020.H483_0102515	1.356e-43	164.0	COG3945@1|root,COG3945@2|Bacteria,2I4J6@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
LZS3_k127_6766617_3	1445613.JALM01000042_gene1756	6.303e-33	145.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4DZDD@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_6766617_0	404589.Anae109_1335	2.321e-99	328.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,43BC6@68525|delta/epsilon subdivisions,2X255@28221|Deltaproteobacteria,2YY92@29|Myxococcales	28221|Deltaproteobacteria	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
LZS3_k127_6766617_4	1283300.ATXB01000002_gene3058	5.985e-13	74.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
LZS3_k127_6766617_1	113395.AXAI01000006_gene1825	6.061e-86	311.0	COG2141@1|root,COG2141@2|Bacteria,1MWDV@1224|Proteobacteria,2TV51@28211|Alphaproteobacteria,3JWDH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_6774827_1	391625.PPSIR1_04508	1.583e-26	116.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
LZS3_k127_6774827_0	391625.PPSIR1_04523	2.353e-141	484.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,42P70@68525|delta/epsilon subdivisions,2WJGD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
LZS3_k127_6799341_7	1128421.JAGA01000004_gene2699	2.574e-32	128.0	COG0384@1|root,COG0384@2|Bacteria,2NR2U@2323|unclassified Bacteria	2|Bacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
LZS3_k127_6799341_1	485913.Krac_11808	5.88e-94	327.0	COG0473@1|root,COG0473@2|Bacteria,2G66J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.87	ko:K05824	ko00300,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map01100,map01120,map01130,map01210,map01230	M00030,M00433	R01934,R01936,R04862	RC00084,RC00114,RC00626	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS3_k127_6799341_5	867903.ThesuDRAFT_01082	1.032e-39	158.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3WD25@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
LZS3_k127_6799341_0	429009.Adeg_1100	1.452e-99	370.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,42FQ2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
LZS3_k127_6799341_2	1232683.ADIMK_0558	8.809e-62	226.0	COG2334@1|root,COG2334@2|Bacteria,1PGM7@1224|Proteobacteria,1RNPA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	homoserine kinase type II (Protein kinase fold)	-	-	-	-	-	-	-	-	-	-	-	-	APH
LZS3_k127_6799341_8	1476583.DEIPH_ctg004orf0092	1.612e-30	129.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Esterase
LZS3_k127_6799341_6	290397.Adeh_3805	2.035e-36	143.0	COG2020@1|root,COG2020@2|Bacteria,1RBJE@1224|Proteobacteria,42XPQ@68525|delta/epsilon subdivisions,2WT34@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
LZS3_k127_6799341_9	161528.ED21_18852	4.092e-14	82.0	COG4094@1|root,COG4094@2|Bacteria,1RDF9@1224|Proteobacteria,2U7NM@28211|Alphaproteobacteria,2K2CX@204457|Sphingomonadales	204457|Sphingomonadales	S	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
LZS3_k127_6799341_3	439235.Dalk_3909	2.872e-61	217.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QX@1224|Proteobacteria,431N8@68525|delta/epsilon subdivisions,2WWXI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
LZS3_k127_6799341_4	439235.Dalk_3908	3.572e-61	213.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QU@1224|Proteobacteria,431N3@68525|delta/epsilon subdivisions,2WWWX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
LZS3_k127_6815263_1	706587.Desti_0925	1.126e-67	248.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
LZS3_k127_6815263_0	656024.FsymDg_1675	6.26e-75	262.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS3_k127_6830604_4	83406.HDN1F_25480	3.818e-05	53.0	COG2866@1|root,COG2866@2|Bacteria,1PE32@1224|Proteobacteria,1TBWG@1236|Gammaproteobacteria,1JBBW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
LZS3_k127_6830604_3	1244869.H261_06806	2.193e-21	104.0	COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,2UE4Y@28211|Alphaproteobacteria,2JTCI@204441|Rhodospirillales	204441|Rhodospirillales	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6830604_1	909663.KI867149_gene3370	4.501e-148	494.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
LZS3_k127_6830604_0	1173021.ALWA01000035_gene3933	6.211e-159	546.0	COG0004@1|root,COG0004@2|Bacteria,1G0S8@1117|Cyanobacteria	1117|Cyanobacteria	P	ammonium transporteR	amt1	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS3_k127_6830604_2	158500.BV97_02415	2.09e-49	182.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,2K4IQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
LZS3_k127_6859676_0	272560.BPSS2021	1.038e-170	555.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,2W26D@28216|Betaproteobacteria,1KADQ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	to Mus musculus sphingosine-1-phosphate lyase Sgpl1 SWALL O54955 (EMBL AF036894) (568 aa) fasta scores E()	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
LZS3_k127_6859676_2	1434929.X946_727	2.123e-121	407.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VPTU@28216|Betaproteobacteria,1KDJU@119060|Burkholderiaceae	28216|Betaproteobacteria	G	FGGY family of carbohydrate kinase, N-terminal domain protein	xylB2	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
LZS3_k127_6859676_7	1403819.BATR01000133_gene4709	1.259e-30	135.0	2941A@1|root,2ZRG3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6859676_8	768671.ThimaDRAFT_1551	2.762e-18	98.0	COG1216@1|root,COG1216@2|Bacteria,1RIUC@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6859676_4	861299.J421_2419	1.331e-77	278.0	2C4I0@1|root,32SKD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6859676_9	946362.XP_004997351.1	3.3e-14	84.0	28K45@1|root,2QSIP@2759|Eukaryota,38E3S@33154|Opisthokonta	33154|Opisthokonta	T	regulation of lateral motor column neuron migration	RELN	GO:0000902,GO:0000904,GO:0001101,GO:0001764,GO:0001932,GO:0001934,GO:0001941,GO:0003002,GO:0003008,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0006950,GO:0006996,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007416,GO:0007417,GO:0007420,GO:0007494,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007616,GO:0007626,GO:0008104,GO:0008150,GO:0008152,GO:0008306,GO:0008347,GO:0009410,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010001,GO:0010033,GO:0010035,GO:0010038,GO:0010226,GO:0010243,GO:0010468,GO:0010469,GO:0010556,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0014066,GO:0014068,GO:0014070,GO:0016043,GO:0016310,GO:0016358,GO:0016477,GO:0017085,GO:0018108,GO:0018193,GO:0018212,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0021510,GO:0021511,GO:0021517,GO:0021536,GO:0021537,GO:0021542,GO:0021543,GO:0021761,GO:0021766,GO:0021769,GO:0021795,GO:0021799,GO:0021800,GO:0021801,GO:0021819,GO:0021854,GO:0021885,GO:0021987,GO:0022008,GO:0022029,GO:0022030,GO:0022603,GO:0022604,GO:0022607,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030154,GO:0030182,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030900,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031326,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031503,GO:0031644,GO:0031646,GO:0031960,GO:0032006,GO:0032008,GO:0032268,GO:0032270,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032570,GO:0032793,GO:0032870,GO:0032879,GO:0032989,GO:0032990,GO:0033036,GO:0033555,GO:0033674,GO:0033993,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035176,GO:0035295,GO:0035418,GO:0035690,GO:0036211,GO:0036477,GO:0038026,GO:0040011,GO:0040012,GO:0040017,GO:0042063,GO:0042221,GO:0042325,GO:0042327,GO:0042330,GO:0042391,GO:0042493,GO:0042995,GO:0043005,GO:0043025,GO:0043085,GO:0043113,GO:0043170,GO:0043200,GO:0043204,GO:0043269,GO:0043270,GO:0043412,GO:0043549,GO:0044057,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044421,GO:0044424,GO:0044463,GO:0044464,GO:0045471,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045859,GO:0045860,GO:0045937,GO:0046677,GO:0048167,GO:0048265,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048565,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048667,GO:0048678,GO:0048699,GO:0048731,GO:0048812,GO:0048814,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050730,GO:0050731,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050803,GO:0050804,GO:0050806,GO:0050807,GO:0050808,GO:0050877,GO:0050890,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051057,GO:0051090,GO:0051091,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051270,GO:0051272,GO:0051338,GO:0051347,GO:0051384,GO:0051385,GO:0051412,GO:0051602,GO:0051641,GO:0051668,GO:0051674,GO:0051703,GO:0051704,GO:0051705,GO:0051716,GO:0051960,GO:0051962,GO:0051966,GO:0051968,GO:0055123,GO:0060255,GO:0060284,GO:0060291,GO:0060322,GO:0060998,GO:0060999,GO:0061001,GO:0061003,GO:0061024,GO:0061097,GO:0061098,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070325,GO:0070326,GO:0070542,GO:0070727,GO:0070887,GO:0070925,GO:0071310,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072578,GO:0072657,GO:0080090,GO:0090128,GO:0090129,GO:0097106,GO:0097107,GO:0097114,GO:0097119,GO:0097120,GO:0097305,GO:0097327,GO:0097447,GO:0097458,GO:0097475,GO:0097476,GO:0097477,GO:0097485,GO:0098698,GO:0098815,GO:0099068,GO:0099084,GO:0099173,GO:0099175,GO:0099177,GO:0099601,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:1900006,GO:1900271,GO:1900273,GO:1900449,GO:1900451,GO:1901564,GO:1901654,GO:1901655,GO:1901698,GO:1901700,GO:1901701,GO:1902076,GO:1902078,GO:1902531,GO:1902533,GO:1903506,GO:1904062,GO:1904064,GO:1904861,GO:1905483,GO:1905485,GO:2000026,GO:2000112,GO:2000145,GO:2000147,GO:2000273,GO:2000310,GO:2000311,GO:2000463,GO:2000969,GO:2001141,GO:2001222,GO:2001224,GO:2001257,GO:2001259	-	ko:K06249	ko04151,ko04510,ko04512,ko05165,map04151,map04510,map04512,map05165	-	-	-	ko00000,ko00001,ko01000,ko04516	-	-	-	EGF_2,Reeler
LZS3_k127_6859676_3	452637.Oter_2323	4.048e-85	300.0	COG3203@1|root,COG3203@2|Bacteria,46SY8@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
LZS3_k127_6859676_5	1313172.YM304_12960	3.681e-53	213.0	COG2267@1|root,COG2267@2|Bacteria,2I79Z@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_6859676_10	498848.TaqDRAFT_4507	8.934e-14	78.0	COG4423@1|root,COG4423@2|Bacteria,1WKIR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Rv0623-like transcription factor	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	PSK_trans_fac
LZS3_k127_6859676_6	1089544.KB912942_gene3115	1.28e-38	152.0	COG3742@1|root,COG3742@2|Bacteria,2IS39@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K19686	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
LZS3_k127_6859676_1	1282876.BAOK01000002_gene509	4.43e-161	518.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TRWW@28211|Alphaproteobacteria,4BR2E@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Cytochrome P450	MA20_04495	-	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_6869367_0	177437.HRM2_06900	7.8e-67	239.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2MIG5@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
LZS3_k127_6869367_1	378806.STAUR_6607	2.126e-16	88.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
LZS3_k127_6895275_0	479434.Sthe_2092	2.395e-103	375.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.1.12.1,3.6.4.12	ko:K01144,ko:K07464,ko:K16898	-	-	-	-	ko00000,ko01000,ko02048,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS3_k127_6895275_1	1034347.CAHJ01000055_gene1133	1.524e-15	84.0	COG3857@1|root,COG3857@2|Bacteria,1TS95@1239|Firmicutes,4I3G2@91061|Bacilli,1ZD3K@1386|Bacillus	91061|Bacilli	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
LZS3_k127_6926233_0	1219084.AP014508_gene244	1.754e-64	241.0	COG2211@1|root,COG2211@2|Bacteria,2GCKM@200918|Thermotogae	200918|Thermotogae	G	MFS/sugar transport protein	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_2
LZS3_k127_6926233_4	414684.RC1_2053	1.341e-17	93.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2UAPV@28211|Alphaproteobacteria,2JSSQ@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
LZS3_k127_6926233_2	314278.NB231_08908	1.602e-40	165.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1WW1D@135613|Chromatiales	135613|Chromatiales	M	PFAM VacJ family lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
LZS3_k127_6926233_3	640511.BC1002_2827	2.229e-30	125.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1K3MD@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
LZS3_k127_6926233_1	243365.CV_0448	1.977e-58	210.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,2KQEA@206351|Neisseriales	206351|Neisseriales	Q	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
LZS3_k127_6939655_0	247633.GP2143_09790	2.419e-159	549.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS3_k127_6939655_1	330214.NIDE3743	3.785e-86	310.0	COG1132@1|root,COG1132@2|Bacteria,3J0X8@40117|Nitrospirae	40117|Nitrospirae	V	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS3_k127_6942192_1	290397.Adeh_1291	1.124e-71	264.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2YWFP@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ C terminal domain	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
LZS3_k127_6942192_2	1142394.PSMK_18350	5.305e-20	100.0	COG1430@1|root,COG1430@2|Bacteria,2J462@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
LZS3_k127_6942192_0	584708.Apau_0519	1.185e-92	323.0	COG1680@1|root,COG1680@2|Bacteria,3TAZG@508458|Synergistetes	508458|Synergistetes	V	PFAM Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_6945462_1	83406.HDN1F_20090	2.909e-87	311.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,1T2GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1,1.8.5.3	ko:K00370,ko:K07306,ko:K17050	ko00910,ko00920,ko01120,ko02020,map00910,map00920,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497,R09501	RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
LZS3_k127_6945462_2	1120973.AQXL01000134_gene1527	3.906e-09	70.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,278A2@186823|Alicyclobacillaceae	91061|Bacilli	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
LZS3_k127_6945462_0	1348657.M622_13650	8.201e-110	375.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,2WGS4@28216|Betaproteobacteria,2KU8N@206389|Rhodocyclales	206389|Rhodocyclales	C	Molydopterin dinucleotide binding domain	-	-	1.17.99.2	ko:K10700,ko:K17050	ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220	-	R05745	RC00275	ko00000,ko00001,ko01000,ko02000	5.A.3.8,5.A.3.9	-	-	Molybdopterin,Molydop_binding
LZS3_k127_6950056_1	926550.CLDAP_28990	1.658e-115	391.0	COG0464@1|root,COG0464@2|Bacteria,2G87K@200795|Chloroflexi	200795|Chloroflexi	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
LZS3_k127_6950056_0	215803.DB30_6707	1.82e-175	576.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria,2YYUH@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
LZS3_k127_6950056_2	234267.Acid_2763	6.211e-15	79.0	COG3291@1|root,COG4625@1|root,COG3291@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	2|Bacteria	M	PKD domain containing protein	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_5,DUF1080,He_PIG,PATR
LZS3_k127_6966957_0	1322246.BN4_11597	3.018e-135	439.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2M8YQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
LZS3_k127_6966957_1	871968.DESME_12360	7.538e-18	86.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,260TC@186807|Peptococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS3_k127_6968023_2	1131269.AQVV01000043_gene1793	1.906e-14	85.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	Asp_protease_2,TPR_19,gag-asp_proteas
LZS3_k127_6968023_0	552811.Dehly_0593	9.48e-56	211.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi,34CZJ@301297|Dehalococcoidia	301297|Dehalococcoidia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
LZS3_k127_6968023_1	1232410.KI421420_gene3180	1.057e-15	79.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,43SSF@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	mttA/Hcf106 family	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
LZS3_k127_6972113_0	1192034.CAP_5247	9.448e-110	371.0	COG3973@1|root,COG3973@2|Bacteria,1P638@1224|Proteobacteria,42MXR@68525|delta/epsilon subdivisions,2WK1Z@28221|Deltaproteobacteria,2Z32G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD_C_2
LZS3_k127_6972113_1	266117.Rxyl_2043	2.295e-36	157.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
LZS3_k127_6976044_3	71139.XP_010062236.1	5.688e-145	483.0	COG0265@1|root,KOG1421@2759|Eukaryota,37M01@33090|Viridiplantae,3G8IE@35493|Streptophyta	35493|Streptophyta	O	protease do-like	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009642,GO:0009644,GO:0009892,GO:0010109,GO:0010205,GO:0016787,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0042548,GO:0043155,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043467,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1905156	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
LZS3_k127_6976044_6	429009.Adeg_1981	2.137e-51	191.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,42GDH@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
LZS3_k127_6976044_1	326427.Cagg_1836	2.63e-189	623.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_6976044_4	85643.Tmz1t_2578	2.586e-119	416.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,2KV2B@206389|Rhodocyclales	206389|Rhodocyclales	E	homoserine dehydrogenase	thrA	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
LZS3_k127_6976044_2	335543.Sfum_1219	3.911e-169	542.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria,2MQW6@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_6976044_5	452637.Oter_3914	1.479e-80	285.0	COG0531@1|root,COG0531@2|Bacteria,46SPF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS3_k127_6976044_0	159087.Daro_3203	5.18e-221	706.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,2KV9E@206389|Rhodocyclales	206389|Rhodocyclales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
LZS3_k127_6988541_2	1207063.P24_02601	1.665e-43	162.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,2JPAY@204441|Rhodospirillales	204441|Rhodospirillales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,His_biosynth
LZS3_k127_6988541_1	1000565.METUNv1_02436	5.199e-98	330.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,2KV5N@206389|Rhodocyclales	206389|Rhodocyclales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS3_k127_6988541_3	338966.Ppro_3053	7.24e-17	85.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria,43VKN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
LZS3_k127_6988541_0	1232410.KI421412_gene98	7.756e-101	344.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,43RZN@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	zinc finger	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
LZS3_k127_6991046_2	1122919.KB905551_gene1801	7.067e-31	132.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,26XF4@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778,ko:K13531	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
LZS3_k127_6991046_1	768671.ThimaDRAFT_0205	1.395e-102	350.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1WWNR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS3_k127_6991046_0	671143.DAMO_1316	4.3e-142	467.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714,ko:K19641	ko02020,map02020	M00500,M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6999751_0	404589.Anae109_3740	1.359e-99	335.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS3_k127_6999751_2	1283287.KB822587_gene979	6.299e-27	121.0	COG2267@1|root,COG2267@2|Bacteria,2I94I@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
LZS3_k127_6999751_1	404589.Anae109_2516	4.235e-35	151.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,2Z0ZJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7069708_1	765913.ThidrDRAFT_2375	5.954e-41	157.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales	135613|Chromatiales	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
LZS3_k127_7069708_0	1232410.KI421424_gene1829	6.452e-73	265.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,43S7G@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
LZS3_k127_7069708_2	1254432.SCE1572_01640	2.521e-35	143.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K02624,ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
LZS3_k127_7074444_0	595536.ADVE02000001_gene1914	1.46e-57	222.0	COG2866@1|root,COG2866@2|Bacteria,1N6CX@1224|Proteobacteria,2U3MG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
LZS3_k127_7084806_2	96561.Dole_0593	1.147e-48	186.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
LZS3_k127_7084806_0	1131269.AQVV01000021_gene2138	3.631e-141	462.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
LZS3_k127_7084806_3	290397.Adeh_2501	1.201e-48	196.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS3_k127_7084806_1	1382359.JIAL01000001_gene1505	2.907e-64	243.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	204432|Acidobacteriia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_709646_0	1125863.JAFN01000001_gene3277	6.168e-82	288.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,dCache_3
LZS3_k127_709646_1	159087.Daro_0970	3.883e-16	92.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,2VIT3@28216|Betaproteobacteria,2KUC5@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
LZS3_k127_709658_0	1123320.KB889717_gene7662	5.622e-39	147.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	cyp	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
LZS3_k127_709658_2	316067.Geob_0257	0.0002279	49.0	2CJPZ@1|root,345ET@2|Bacteria,1NY5K@1224|Proteobacteria,430QV@68525|delta/epsilon subdivisions,2WW5D@28221|Deltaproteobacteria,43VVK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
LZS3_k127_709658_1	1232410.KI421428_gene1212	1.544e-18	100.0	COG0457@1|root,COG0457@2|Bacteria,1R7XY@1224|Proteobacteria,42NFC@68525|delta/epsilon subdivisions,2WMA4@28221|Deltaproteobacteria,43S9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
LZS3_k127_7108431_0	1333523.L593_04960	2.747e-47	189.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_7142159_0	448385.sce6427	2.527e-131	440.0	COG0515@1|root,COG2267@1|root,COG0515@2|Bacteria,COG2267@2|Bacteria,1PEH3@1224|Proteobacteria,430NV@68525|delta/epsilon subdivisions,2WW17@28221|Deltaproteobacteria,2YTSZ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
LZS3_k127_7142714_0	1487953.JMKF01000053_gene1809	3.56e-64	229.0	COG0412@1|root,COG0412@2|Bacteria,1G3JS@1117|Cyanobacteria,1HA80@1150|Oscillatoriales	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
LZS3_k127_7142714_1	1121937.AUHJ01000006_gene2410	1.556e-63	226.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria,467SS@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
LZS3_k127_7142714_2	765910.MARPU_09430	4.79e-47	177.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RPI1@1236|Gammaproteobacteria,1WWK2@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS3_k127_7182001_2	880073.Calab_0209	1.105e-96	335.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	-	-	1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13	ko:K00123,ko:K00317,ko:K00528,ko:K09835	ko00630,ko00680,ko00906,ko01100,ko01110,ko01120,ko01200,map00630,map00680,map00906,map01100,map01110,map01120,map01200	M00097	R00519,R01588,R02511,R07512,R10159	RC00185,RC00556,RC00557,RC00732,RC01960,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4_20,NAD_binding_8,Oxidored_FMN,Pyr_redox_2
LZS3_k127_7182001_0	436229.JOEH01000010_gene5212	6.177e-138	450.0	COG0138@1|root,COG0138@2|Bacteria,2I8U6@201174|Actinobacteria,2NKXY@228398|Streptacidiphilus	201174|Actinobacteria	F	AICARFT/IMPCHase bienzyme	-	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
LZS3_k127_7182001_1	1038869.AXAN01000051_gene5560	1.637e-107	355.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,1K180@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the pyruvate kinase family	ttuE	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
LZS3_k127_7207098_3	580340.Tlie_0592	1.714e-16	94.0	COG0136@1|root,COG0136@2|Bacteria,3TA62@508458|Synergistetes	508458|Synergistetes	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS3_k127_7207098_1	637389.Acaty_c2004	4.272e-118	407.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,2NC1Y@225057|Acidithiobacillales	225057|Acidithiobacillales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS3_k127_7207098_0	289376.THEYE_A0650	7.715e-189	616.0	COG0119@1|root,COG0119@2|Bacteria,3J0F7@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
LZS3_k127_7207098_2	322710.Avin_42490	2.314e-51	192.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
LZS3_k127_7224683_0	1121013.P873_00735	1.056e-89	300.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1X2YU@135614|Xanthomonadales	135614|Xanthomonadales	P	Reversible hydration of carbon dioxide	yadF	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
LZS3_k127_7224683_1	1380355.JNIJ01000027_gene760	0.0004775	50.0	COG1670@1|root,COG1670@2|Bacteria,1R4VC@1224|Proteobacteria,2UEQW@28211|Alphaproteobacteria,3JVY7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Siderophore biosynthesis protein domain	-	-	2.3.1.82	ko:K00663	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_8
LZS3_k127_7263369_2	42256.RradSPS_0259	8.544e-23	110.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CQHA@84995|Rubrobacteria	84995|Rubrobacteria	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS3_k127_7263369_1	1177928.TH2_06338	1.113e-28	127.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,2JP9Y@204441|Rhodospirillales	204441|Rhodospirillales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
LZS3_k127_7263369_4	272134.KB731324_gene2936	0.0003042	51.0	COG0457@1|root,COG5653@1|root,COG0457@2|Bacteria,COG5653@2|Bacteria,1G4MI@1117|Cyanobacteria,1HF7T@1150|Oscillatoriales	1117|Cyanobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS3_k127_7263369_3	399739.Pmen_4121	9.117e-21	106.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1T1K1@1236|Gammaproteobacteria,1YJHF@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	hrp1	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_7263369_0	290397.Adeh_3302	1.062e-83	286.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,4376B@68525|delta/epsilon subdivisions,2X25W@28221|Deltaproteobacteria,2YZ9U@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS3_k127_7266617_1	1123256.KB907925_gene1523	2.333e-42	164.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,1S48Y@1236|Gammaproteobacteria,1XCCY@135614|Xanthomonadales	135614|Xanthomonadales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_7266617_0	665952.HMPREF1015_00799	4.917e-46	175.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1ZCDY@1386|Bacillus	91061|Bacilli	IQ	reductase	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
LZS3_k127_7278666_0	1122176.KB903587_gene4418	6.684e-36	154.0	28KVV@1|root,2ZACB@2|Bacteria,4NHPI@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7320396_1	759362.KVU_0350	0.0005898	51.0	COG3255@1|root,COG3255@2|Bacteria,1N0RD@1224|Proteobacteria,2UBXK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
LZS3_k127_7320396_0	1125863.JAFN01000001_gene985	4.104e-78	271.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
LZS3_k127_7321626_1	13035.Dacsa_0686	0.0006968	44.0	COG0412@1|root,COG0412@2|Bacteria,1G0PH@1117|Cyanobacteria	1117|Cyanobacteria	Q	dienelactone hydrolase	clcD	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
LZS3_k127_7321626_2	1200567.JNKD01000026_gene1431	0.0008302	53.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C,TonB_N
LZS3_k127_7321626_0	555779.Dthio_PD2848	1.808e-65	248.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,43D2X@68525|delta/epsilon subdivisions,2X8A2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
LZS3_k127_7341497_3	1173029.JH980292_gene3118	2.543e-06	54.0	COG1502@1|root,COG1555@1|root,COG1502@2|Bacteria,COG1555@2|Bacteria,1G01I@1117|Cyanobacteria,1H79E@1150|Oscillatoriales	1117|Cyanobacteria	I	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comA	-	-	-	-	-	-	-	-	-	-	-	HHH_3,PLDc_2
LZS3_k127_7341497_1	1397528.Q671_02715	1.749e-35	144.0	COG2885@1|root,COG2885@2|Bacteria,1RENP@1224|Proteobacteria,1S4IW@1236|Gammaproteobacteria,1XJ8G@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the ompA family	oprF	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
LZS3_k127_7341497_0	269799.Gmet_2779	6.302e-76	271.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
LZS3_k127_7341497_2	426117.M446_5110	3.525e-24	108.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,1JRC5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	PFAM aminotransferase class V	nifS	GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS3_k127_7342103_1	1123504.JQKD01000031_gene4537	3.539e-27	113.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,4AAQ4@80864|Comamonadaceae	28216|Betaproteobacteria	C	pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
LZS3_k127_7342103_0	765912.Thimo_1087	0.0	1309.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
LZS3_k127_7357532_3	502025.Hoch_0064	2.076e-17	91.0	COG1309@1|root,COG1309@2|Bacteria,1NP72@1224|Proteobacteria,42T8H@68525|delta/epsilon subdivisions,2WPNA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
LZS3_k127_7357532_0	1120936.KB907209_gene1507	6.073e-91	323.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria,4EFU2@85012|Streptosporangiales	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
LZS3_k127_7357532_2	404589.Anae109_0806	7.025e-21	100.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,2Z1J6@29|Myxococcales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_7357532_1	671143.DAMO_2148	1.257e-48	179.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
LZS3_k127_7357532_4	478741.JAFS01000002_gene501	1.058e-14	87.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
LZS3_k127_7368516_2	1169154.KB897783_gene4658	5.33e-11	70.0	COG3217@1|root,COG3217@2|Bacteria,2GPWY@201174|Actinobacteria	201174|Actinobacteria	S	MOSC domain protein beta barrel domain protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
LZS3_k127_7368516_1	290397.Adeh_0547	3.02e-69	243.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,42X9X@68525|delta/epsilon subdivisions,2X3AH@28221|Deltaproteobacteria,2YV4Q@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
LZS3_k127_7368516_0	1380394.JADL01000023_gene48	1.878e-86	296.0	COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,2VEUG@28211|Alphaproteobacteria,2JRY8@204441|Rhodospirillales	204441|Rhodospirillales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS3_k127_7375007_0	309801.trd_1756	8.361e-166	533.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi,27Y0A@189775|Thermomicrobia	189775|Thermomicrobia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS3_k127_7375007_1	42256.RradSPS_0719	7.005e-42	174.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,4CP9F@84995|Rubrobacteria	84995|Rubrobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
LZS3_k127_7388354_1	290397.Adeh_0070	3.921e-45	175.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2WPQK@28221|Deltaproteobacteria,2Z324@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
LZS3_k127_7388354_2	290397.Adeh_0015	1.448e-18	93.0	COG3266@1|root,COG3266@2|Bacteria,1N9VA@1224|Proteobacteria,42VXQ@68525|delta/epsilon subdivisions,2WSBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7388354_3	880073.Calab_0230	7.053e-18	95.0	COG0355@1|root,COG0355@2|Bacteria,2NPSQ@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195,iJN746.PP_5412,iSbBS512_1146.SbBS512_E4190	ATP-synt_DE,ATP-synt_DE_N
LZS3_k127_7388354_0	1121918.ARWE01000001_gene3512	4.607e-106	346.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,43S0H@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS3_k127_7426738_0	589865.DaAHT2_0078	6.787e-127	413.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MJ0G@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
LZS3_k127_7426738_1	1132509.C447_07518	1.505e-12	76.0	COG1011@1|root,arCOG02291@2157|Archaea,2XT5H@28890|Euryarchaeota,23V2M@183963|Halobacteria	183963|Halobacteria	S	hydrolase (HAD superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS3_k127_7428867_3	1121920.AUAU01000001_gene2220	2.7e-06	59.0	COG4313@1|root,COG4313@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
LZS3_k127_7428867_2	631362.Thi970DRAFT_04016	7.913e-16	91.0	COG0526@1|root,COG0526@2|Bacteria,1RJUZ@1224|Proteobacteria,1S6Y0@1236|Gammaproteobacteria,1WYNQ@135613|Chromatiales	135613|Chromatiales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_7428867_0	595460.RRSWK_07231	3.176e-49	182.0	COG4914@1|root,COG4914@2|Bacteria,2J4D4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7428867_1	1286106.MPL1_07443	8.352e-49	180.0	COG3040@1|root,COG3040@2|Bacteria,1RIKA@1224|Proteobacteria,1T0AA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer Membrane Lipoprotein	blc4	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
LZS3_k127_743153_7	243231.GSU1870	2.321e-08	66.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2WMIG@28221|Deltaproteobacteria,43W33@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
LZS3_k127_743153_1	670487.Ocepr_1994	1.054e-126	415.0	COG0686@1|root,COG0686@2|Bacteria,1WIQ6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
LZS3_k127_743153_0	521674.Plim_1772	6.561e-141	459.0	COG2046@1|root,COG2046@2|Bacteria,2J517@203682|Planctomycetes	203682|Planctomycetes	H	sulfate adenylyltransferase	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
LZS3_k127_743153_4	1502770.JQMG01000001_gene522	2.803e-14	86.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,2KKVW@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS3_k127_743153_5	1131269.AQVV01000016_gene1868	5.472e-13	78.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	2.7.7.80,2.8.1.11,3.13.1.6	ko:K21140,ko:K21147	ko04122,map04122	-	R07459,R07461,R11524	RC00043,RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,Rhodanese,ThiF
LZS3_k127_743153_2	631362.Thi970DRAFT_03186	1.499e-36	153.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,1X0B5@135613|Chromatiales	135613|Chromatiales	M	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
LZS3_k127_743153_6	439235.Dalk_2127	1.17e-09	70.0	COG5276@1|root,COG5492@1|root,COG5276@2|Bacteria,COG5492@2|Bacteria,1R8Z4@1224|Proteobacteria,42U3Q@68525|delta/epsilon subdivisions,2WQZX@28221|Deltaproteobacteria,2MKPP@213118|Desulfobacterales	28221|Deltaproteobacteria	N	PFAM Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566,Peptidase_C13
LZS3_k127_743153_3	1125863.JAFN01000001_gene2869	1.1e-22	106.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,42V63@68525|delta/epsilon subdivisions,2WPE9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	transcriptional regulator	iscR-2	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
LZS3_k127_7438219_2	1122604.JONR01000025_gene4558	1.54e-29	129.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,1S2MJ@1236|Gammaproteobacteria,1X6B4@135614|Xanthomonadales	135614|Xanthomonadales	S	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_7438219_0	471852.Tcur_0349	5.511e-109	362.0	COG3250@1|root,COG3250@2|Bacteria,2HF52@201174|Actinobacteria,4EMA2@85012|Streptosporangiales	201174|Actinobacteria	G	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
LZS3_k127_7438219_1	247634.GPB2148_2309	6.118e-80	273.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,1RNEZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_7442149_0	706587.Desti_2514	5.885e-156	507.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1QU0I@1224|Proteobacteria,42M4R@68525|delta/epsilon subdivisions,2WK1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	yprA	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C,RNase_H_2
LZS3_k127_7445613_1	1446473.JHWH01000020_gene3873	1.013e-77	271.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2PU7H@265|Paracoccus	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
LZS3_k127_7445613_3	29486.NJ56_01865	9.728e-11	74.0	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,1S3W5@1236|Gammaproteobacteria,41G2W@629|Yersinia	1236|Gammaproteobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008177,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016627,GO:0016635,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	iPC815.YPO0357,ic_1306.c5239	Fumarate_red_D
LZS3_k127_7445613_4	243365.CV_3367	0.0003	49.0	COG3029@1|root,COG3029@2|Bacteria,1RD34@1224|Proteobacteria,2VTQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Fumarate reductase subunit C	frdC	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
LZS3_k127_7445613_0	1137799.GZ78_02265	1.366e-86	301.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1XI5Y@135619|Oceanospirillales	135619|Oceanospirillales	C	Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration	-	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
LZS3_k127_7445613_2	71421.HI_0835	1.801e-29	123.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1Y7RE@135625|Pasteurellales	135625|Pasteurellales	C	fumarate reductase, flavoprotein subunit	frdA	GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0022900,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS3_k127_7452649_3	926569.ANT_15860	4.959e-30	140.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
LZS3_k127_7452649_0	357808.RoseRS_0780	1.408e-211	677.0	COG0438@1|root,COG0500@1|root,COG0438@2|Bacteria,COG2226@2|Bacteria,2G84C@200795|Chloroflexi,375HH@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11
LZS3_k127_7452649_2	1173020.Cha6605_4673	7.758e-35	144.0	COG1215@1|root,COG1215@2|Bacteria,1G7KN@1117|Cyanobacteria	1117|Cyanobacteria	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
LZS3_k127_7452649_1	1280952.HJA_05892	1.237e-92	347.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2TSS4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	5.1.1.20,5.5.1.1	ko:K01856,ko:K19802	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229,R10938	RC00903,RC01038,RC01108,RC01321,RC01356,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_7452649_4	246200.SPO2830	5.919e-17	96.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TXAW@28211|Alphaproteobacteria,4NBEB@97050|Ruegeria	28211|Alphaproteobacteria	S	hmm pf01979	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_7455573_1	518766.Rmar_0135	2.652e-55	200.0	COG1181@1|root,COG1181@2|Bacteria,4PEAY@976|Bacteroidetes,1FIPX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
LZS3_k127_7455573_0	518766.Rmar_0136	5.039e-161	525.0	COG1509@1|root,COG1509@2|Bacteria,4NJ79@976|Bacteroidetes,1FJ3Z@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Lysine-2,3-aminomutase	ablA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
LZS3_k127_7457556_6	318996.AXAZ01000044_gene2115	8.658e-34	142.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,2TRG9@28211|Alphaproteobacteria,3JSZK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	MA20_14090	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_7457556_7	1121035.AUCH01000004_gene249	4.982e-20	93.0	COG2261@1|root,COG2261@2|Bacteria,1NE11@1224|Proteobacteria	1224|Proteobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
LZS3_k127_7457556_0	234267.Acid_5780	2.121e-253	834.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
LZS3_k127_7457556_5	1440774.Y900_019020	2.49e-34	154.0	COG2114@1|root,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria,234SY@1762|Mycobacteriaceae	201174|Actinobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
LZS3_k127_7457556_1	663610.JQKO01000003_gene1467	3.233e-195	625.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2U43Z@28211|Alphaproteobacteria,3NCZF@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	TrkA-N domain	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
LZS3_k127_7457556_2	1121015.N789_03295	4.569e-109	365.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,1X61U@135614|Xanthomonadales	135614|Xanthomonadales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
LZS3_k127_7457556_4	469383.Cwoe_1310	3.169e-90	325.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4CSBE@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_7457556_8	261292.Nit79A3_0082	1.51e-19	88.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2VVYY@28216|Betaproteobacteria,374GW@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
LZS3_k127_7457556_3	414684.RC1_3798	4.053e-93	319.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TSHC@28211|Alphaproteobacteria,2JR9C@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS3_k127_7458064_0	1120972.AUMH01000007_gene1741	7.098e-72	257.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF_1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_7458064_2	224324.aq_1717a	2.379e-26	118.0	COG0236@1|root,COG0236@2|Bacteria,2G491@200783|Aquificae	200783|Aquificae	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS3_k127_7458064_1	483219.LILAB_31805	3.643e-43	162.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,2YU16@29|Myxococcales	28221|Deltaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
LZS3_k127_7460500_0	1033743.CAES01000019_gene3302	8.341e-130	436.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26QQ1@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
LZS3_k127_7469400_0	1236973.JCM9157_1472	1.689e-49	190.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,1ZBXG@1386|Bacillus	91061|Bacilli	D	COG1192 ATPases involved in chromosome partitioning	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS3_k127_7469400_1	502025.Hoch_0054	1.839e-21	104.0	COG0457@1|root,COG0789@1|root,COG0457@2|Bacteria,COG0789@2|Bacteria,1PQD2@1224|Proteobacteria,4323R@68525|delta/epsilon subdivisions,2WXJB@28221|Deltaproteobacteria,2Z10C@29|Myxococcales	28221|Deltaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_1,TPR_17,TPR_8
LZS3_k127_7475058_0	1469245.JFBG01000086_gene1608	1.416e-186	597.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,1RN40@1236|Gammaproteobacteria,1X2WW@135613|Chromatiales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	yagR	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS3_k127_7483260_2	246197.MXAN_0153	6.275e-05	53.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
LZS3_k127_7483260_3	1144275.COCOR_06953	0.0004775	50.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg,RsbRD_N
LZS3_k127_7483260_1	1122611.KB903996_gene7554	4.545e-05	51.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria,4EFFN@85012|Streptosporangiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
LZS3_k127_7483260_0	67352.JODS01000010_gene4801	7.993e-06	53.0	COG2021@1|root,COG2021@2|Bacteria,2IA6N@201174|Actinobacteria	201174|Actinobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_7492118_2	290397.Adeh_0078	1.057e-39	158.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7492118_3	671143.DAMO_1287	7.629e-08	65.0	COG2801@1|root,COG2801@2|Bacteria,2NQ4I@2323|unclassified Bacteria	2|Bacteria	L	Homeodomain-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
LZS3_k127_7492118_1	1123258.AQXZ01000019_gene3359	5.133e-68	256.0	COG1024@1|root,COG1024@2|Bacteria,2H2U8@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_7492118_0	502025.Hoch_6012	1.363e-95	327.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2WKJY@28221|Deltaproteobacteria,2Z2YT@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS3_k127_7499496_0	398767.Glov_2702	9.906e-170	546.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
LZS3_k127_7504930_0	595460.RRSWK_03757	0.0	1187.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,2IYDT@203682|Planctomycetes	203682|Planctomycetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS3_k127_7504930_2	1121396.KB893052_gene3387	1.669e-16	95.0	COG1102@1|root,COG1102@2|Bacteria,1RCTZ@1224|Proteobacteria,42R0B@68525|delta/epsilon subdivisions,2WMVD@28221|Deltaproteobacteria,2MJH5@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
LZS3_k127_7504930_1	290397.Adeh_0078	2.619e-38	149.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7525866_0	592015.HMPREF1705_00550	1.468e-112	384.0	COG1004@1|root,COG1004@2|Bacteria,3TA84@508458|Synergistetes	508458|Synergistetes	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS3_k127_7525866_1	1125863.JAFN01000001_gene322	4.147e-92	311.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS3_k127_7559436_0	1519464.HY22_07040	2.105e-163	533.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1FEF9@1090|Chlorobi	1090|Chlorobi	C	electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
LZS3_k127_7559436_3	290397.Adeh_1041	1.072e-35	140.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2X3DV@28221|Deltaproteobacteria,2YVMF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
LZS3_k127_7559436_4	909663.KI867150_gene1264	1.245e-15	89.0	2C469@1|root,33HZ0@2|Bacteria,1NNDA@1224|Proteobacteria,42R4S@68525|delta/epsilon subdivisions,2WMQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7559436_5	391625.PPSIR1_24539	2.673e-12	76.0	COG1309@1|root,COG1309@2|Bacteria,1Q5BW@1224|Proteobacteria,42TMA@68525|delta/epsilon subdivisions,2WZPQ@28221|Deltaproteobacteria,2Z2HA@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
LZS3_k127_7559436_1	1146883.BLASA_1876	1.921e-49	187.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS3_k127_7559436_2	264462.Bd3648	2.126e-47	191.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9,dCache_1
LZS3_k127_7568513_3	629773.AORY01000005_gene2605	4.124e-19	99.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2TSW4@28211|Alphaproteobacteria,2K1BG@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
LZS3_k127_7568513_0	402881.Plav_0960	2.2e-250	822.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,1JN93@119043|Rhodobiaceae	28211|Alphaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_7568513_4	1157708.KB907454_gene3010	2.734e-17	92.0	COG5517@1|root,COG5517@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
LZS3_k127_7568513_1	644966.Tmar_0478	1.709e-156	523.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
LZS3_k127_7568513_2	1348657.M622_02865	1.904e-30	124.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.2.5.3	ko:K03520,ko:K09386	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	COXG
LZS3_k127_7592099_4	1123386.AUIW01000009_gene1812	3.328e-23	110.0	COG1848@1|root,COG1848@2|Bacteria,1WKJ4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7592099_5	1449976.KALB_8753	0.000255	47.0	COG4118@1|root,COG4118@2|Bacteria,2HPA7@201174|Actinobacteria,4E7WH@85010|Pseudonocardiales	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
LZS3_k127_7592099_1	292459.STH2651	6.015e-80	286.0	COG0665@1|root,COG0665@2|Bacteria,1TR1R@1239|Firmicutes	1239|Firmicutes	CE	FAD dependent oxidoreductase	puuB	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
LZS3_k127_7592099_2	216594.MMAR_3134	1.526e-70	248.0	COG1305@1|root,COG1305@2|Bacteria,2GMGI@201174|Actinobacteria,236SX@1762|Mycobacteriaceae	201174|Actinobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
LZS3_k127_7592099_0	402881.Plav_1165	1.006e-270	855.0	COG2072@1|root,COG2072@2|Bacteria,1NSY9@1224|Proteobacteria,2TUSD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Flavoprotein involved in K transport	MA20_26775	-	1.14.13.22	ko:K03379	ko00930,ko01120,ko01220,map00930,map01120,map01220	-	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko01000	-	-	-	NAD_binding_8,Pyr_redox_2,Pyr_redox_3
LZS3_k127_7592099_3	1122622.ATWJ01000008_gene2980	6.313e-58	212.0	COG1506@1|root,COG1506@2|Bacteria,2HFMK@201174|Actinobacteria,4FJMA@85021|Intrasporangiaceae	201174|Actinobacteria	E	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
LZS3_k127_7616710_0	443143.GM18_0717	1.679e-53	199.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS3_k127_7616710_4	1122180.Lokhon_00983	7.085e-08	64.0	COG3360@1|root,COG3360@2|Bacteria,1PURT@1224|Proteobacteria,2V0YH@28211|Alphaproteobacteria,2P9ZI@245186|Loktanella	28211|Alphaproteobacteria	S	Dodecin	-	-	-	-	-	-	-	-	-	-	-	-	Dodecin
LZS3_k127_7616710_3	1122180.Lokhon_00983	1.185e-09	64.0	COG3360@1|root,COG3360@2|Bacteria,1PURT@1224|Proteobacteria,2V0YH@28211|Alphaproteobacteria,2P9ZI@245186|Loktanella	28211|Alphaproteobacteria	S	Dodecin	-	-	-	-	-	-	-	-	-	-	-	-	Dodecin
LZS3_k127_7616710_1	1131269.AQVV01000016_gene1841	3.843e-32	138.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS3_k127_7616710_2	926566.Terro_3779	3.683e-10	72.0	COG0354@1|root,COG0354@2|Bacteria,3Y2PI@57723|Acidobacteria,2JJ3H@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
LZS3_k127_7647988_1	1144312.PMI09_04044	8.044e-16	83.0	COG0395@1|root,COG0395@2|Bacteria,1R8V2@1224|Proteobacteria,2U3FE@28211|Alphaproteobacteria,4B7PM@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter permease	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS3_k127_7647988_0	290397.Adeh_4137	2.828e-90	316.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.20	ko:K05816,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
LZS3_k127_7647988_2	64363.EME42152	0.0001109	46.0	COG1877@1|root,KOG1050@2759|Eukaryota,38EGS@33154|Opisthokonta,3NUM3@4751|Fungi,3QP00@4890|Ascomycota,1ZZPD@147541|Dothideomycetes,3MF1V@451867|Dothideomycetidae	4751|Fungi	G	UDP-glucose-glucosephosphate glucosyltransferase	TPS1	GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0003825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005946,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0006974,GO:0006979,GO:0007049,GO:0007154,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009266,GO:0009269,GO:0009311,GO:0009312,GO:0009405,GO:0009408,GO:0009409,GO:0009414,GO:0009415,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009653,GO:0009987,GO:0009991,GO:0010035,GO:0016051,GO:0016311,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0030447,GO:0031668,GO:0032502,GO:0032505,GO:0032991,GO:0033554,GO:0034293,GO:0034599,GO:0034605,GO:0034614,GO:0034637,GO:0035251,GO:0035690,GO:0036168,GO:0036180,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0042578,GO:0042631,GO:0043934,GO:0043935,GO:0044182,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0046351,GO:0046527,GO:0046677,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0051321,GO:0051704,GO:0051716,GO:0070301,GO:0070413,GO:0070414,GO:0070415,GO:0070417,GO:0070887,GO:0071214,GO:0071229,GO:0071236,GO:0071462,GO:0071465,GO:0071496,GO:0071704,GO:0090441,GO:0097237,GO:0104004,GO:1901576,GO:1901700,GO:1901701,GO:1902494,GO:1903046,GO:1990234	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
LZS3_k127_7649121_0	471852.Tcur_2583	1.051e-95	337.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
LZS3_k127_7649121_1	1219035.NT2_04_00120	4.002e-28	122.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
LZS3_k127_7695691_1	1168065.DOK_03638	9.912e-72	259.0	COG1028@1|root,COG1028@2|Bacteria,1R6W8@1224|Proteobacteria,1RY7D@1236|Gammaproteobacteria,1J8ZG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_7695691_0	1123368.AUIS01000033_gene1374	1.62e-161	527.0	COG3131@1|root,COG3131@2|Bacteria,1MUNX@1224|Proteobacteria,1RMEB@1236|Gammaproteobacteria,2NCM6@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)	-	-	-	ko:K03670	-	-	-	-	ko00000	-	-	-	MdoG
LZS3_k127_7696992_0	502025.Hoch_0348	2.378e-78	276.0	COG1621@1|root,COG1621@2|Bacteria,1RCMP@1224|Proteobacteria,432Y7@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7696992_1	1121861.KB899917_gene3614	3.446e-73	267.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,2JQMB@204441|Rhodospirillales	204441|Rhodospirillales	L	COG2818 3-methyladenine DNA glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
LZS3_k127_7696992_2	945713.IALB_1077	2.082e-45	168.0	COG1970@1|root,COG1970@2|Bacteria	2|Bacteria	M	mechanosensitive ion channel activity	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
LZS3_k127_7696992_3	660470.Theba_1301	5.615e-27	114.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS3_k127_7698134_1	448385.sce0666	1.301e-89	306.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YZGR@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
LZS3_k127_7698134_3	768671.ThimaDRAFT_1314	7.248e-09	62.0	2EC1X@1|root,33612@2|Bacteria,1NER9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HicB
LZS3_k127_7698134_2	671143.DAMO_0814	1.959e-32	137.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
LZS3_k127_7698134_0	596151.DesfrDRAFT_3282	0.0	1059.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2M817@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
LZS3_k127_7699639_2	1128421.JAGA01000001_gene2034	2.309e-27	128.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
LZS3_k127_7699639_0	1048339.KB913029_gene4599	2.766e-76	282.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4ERC7@85013|Frankiales	201174|Actinobacteria	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
LZS3_k127_7699639_1	251221.35211954	1.085e-67	243.0	COG0003@1|root,COG0003@2|Bacteria,1G1UB@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM arsenite-activated ATPase ArsA	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
LZS3_k127_7718125_1	350054.Mflv_5002	2.757e-09	70.0	COG0589@1|root,COG0589@2|Bacteria,2ICPM@201174|Actinobacteria,233J9@1762|Mycobacteriaceae	201174|Actinobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_7718125_0	1127134.NOCYR_1614	2.955e-152	492.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,4FWXS@85025|Nocardiaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
LZS3_k127_7726163_1	1385935.N836_20445	1.093e-05	57.0	COG2351@1|root,COG2931@1|root,COG3409@1|root,COG5306@1|root,COG5434@1|root,COG2351@2|Bacteria,COG2931@2|Bacteria,COG3409@2|Bacteria,COG5306@2|Bacteria,COG5434@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
LZS3_k127_7726163_2	443143.GM18_0916	1.446e-05	57.0	COG2133@1|root,COG4447@1|root,COG4733@1|root,COG2133@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,1PFCA@1224|Proteobacteria,42WUH@68525|delta/epsilon subdivisions,2WT3I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
LZS3_k127_7726163_3	1385935.N836_20445	0.0007048	51.0	COG2351@1|root,COG2931@1|root,COG3409@1|root,COG5306@1|root,COG5434@1|root,COG2351@2|Bacteria,COG2931@2|Bacteria,COG3409@2|Bacteria,COG5306@2|Bacteria,COG5434@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
LZS3_k127_7726163_0	1254432.SCE1572_50735	7.159e-07	60.0	COG0625@1|root,COG0625@2|Bacteria,1MX33@1224|Proteobacteria,439KN@68525|delta/epsilon subdivisions,2X4XG@28221|Deltaproteobacteria,2YZSS@29|Myxococcales	28221|Deltaproteobacteria	O	Glutathione S-transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_6,GST_N_4
LZS3_k127_7735772_2	1265310.CCBD010000038_gene2330	2.181e-07	55.0	COG1960@1|root,COG1960@2|Bacteria,2HXD5@201174|Actinobacteria,235J6@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_7735772_0	1280953.HOC_14008	1.485e-137	454.0	COG1960@1|root,COG1960@2|Bacteria,1P8I7@1224|Proteobacteria,2U0AW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_7735772_1	1292034.OR37_01184	6.612e-14	76.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2U3E8@28211|Alphaproteobacteria,2KFD0@204458|Caulobacterales	204458|Caulobacterales	J	pseudouridine synthase	-	-	5.4.99.24,5.4.99.28,5.4.99.29	ko:K06177,ko:K06179	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
LZS3_k127_7750434_3	1215092.PA6_008_00700	3.765e-73	253.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,1RPB1@1236|Gammaproteobacteria,1YF9J@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	dedA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
LZS3_k127_7750434_1	404589.Anae109_2790	1.352e-130	430.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,42MZ6@68525|delta/epsilon subdivisions,2WJXZ@28221|Deltaproteobacteria,2YUTQ@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
LZS3_k127_7750434_2	768671.ThimaDRAFT_2796	7.063e-84	285.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,1WXDY@135613|Chromatiales	135613|Chromatiales	V	pfam abc	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_7750434_5	269799.Gmet_2406	3.238e-51	209.0	COG4591@1|root,COG4591@2|Bacteria,1QXNJ@1224|Proteobacteria,43C4I@68525|delta/epsilon subdivisions,2X7EY@28221|Deltaproteobacteria,43TJA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_7750434_4	886293.Sinac_1758	3.369e-66	240.0	COG0577@1|root,COG0577@2|Bacteria,2IZAQ@203682|Planctomycetes	203682|Planctomycetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS3_k127_7750434_6	1163408.UU9_07491	4.782e-45	189.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,1X3ST@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS3_k127_7750434_7	290397.Adeh_0078	3.537e-40	159.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7750434_0	530564.Psta_1035	6.135e-186	590.0	COG1055@1|root,COG1055@2|Bacteria,2IY4X@203682|Planctomycetes	203682|Planctomycetes	P	COG1055 Na H antiporter NhaD and related arsenite	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
LZS3_k127_7754223_0	867903.ThesuDRAFT_02283	1.614e-175	569.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WCD6@538999|Clostridiales incertae sedis	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS3_k127_7759724_3	1242864.D187_003811	0.0005692	43.0	COG1986@1|root,COG1986@2|Bacteria,1Q6S4@1224|Proteobacteria,433PP@68525|delta/epsilon subdivisions,2WX89@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Protein of unknown function DUF84	-	-	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
LZS3_k127_7759724_0	991905.SL003B_3490	1.633e-128	426.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,4BPE3@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	TIGRFAM glutamate--cysteine ligase, plant type	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
LZS3_k127_7759724_2	1535422.ND16A_2142	3.656e-26	115.0	COG3339@1|root,COG3339@2|Bacteria,1RAN7@1224|Proteobacteria,1S291@1236|Gammaproteobacteria,2Q6RN@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
LZS3_k127_7759724_1	443144.GM21_2368	3.385e-33	145.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42R7R@68525|delta/epsilon subdivisions,2WMT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS,Response_reg
LZS3_k127_7765414_3	1030157.AFMP01000040_gene1452	1.536e-60	238.0	COG2141@1|root,COG2141@2|Bacteria,1PGTP@1224|Proteobacteria,2UZFT@28211|Alphaproteobacteria,2K8SR@204457|Sphingomonadales	204457|Sphingomonadales	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_7765414_6	1173023.KE650771_gene2163	3.708e-24	119.0	2E8PN@1|root,3330T@2|Bacteria,1GFR6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7765414_2	1219035.NT2_07_01520	1.088e-69	252.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	cyp191A3	-	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_7765414_5	1121924.ATWH01000004_gene2316	2.779e-28	134.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944	-	ko:K16260	ko00680,ko01120,map00680,map01120	-	-	-	ko00000,ko00001	-	-	-	Polyketide_cyc2
LZS3_k127_7765414_0	1206731.BAGB01000147_gene4240	1.915e-139	465.0	COG1053@1|root,COG1053@2|Bacteria,2IA7Q@201174|Actinobacteria,4G5SH@85025|Nocardiaceae	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
LZS3_k127_7765414_4	1030157.AFMP01000009_gene3648	1.54e-39	155.0	COG1309@1|root,COG1309@2|Bacteria,1RCFF@1224|Proteobacteria,2UB62@28211|Alphaproteobacteria,2KDHX@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
LZS3_k127_7765414_1	1123320.KB889687_gene937	5.924e-118	389.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_7775767_1	765910.MARPU_14455	4.278e-29	133.0	COG3379@1|root,COG3379@2|Bacteria,1PWC6@1224|Proteobacteria,1TKB0@1236|Gammaproteobacteria,1X1DI@135613|Chromatiales	135613|Chromatiales	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_7775767_2	1198232.CYCME_1386	7.636e-29	121.0	2E31J@1|root,32Y1Y@2|Bacteria,1N745@1224|Proteobacteria,1SCMM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
LZS3_k127_7775767_0	370438.PTH_0501	3.264e-77	273.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,2602H@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS3_k127_7781279_2	713586.KB900536_gene961	7.345e-14	72.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1WWDG@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_7781279_1	1411123.JQNH01000001_gene3809	2.425e-193	614.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_7781279_0	1254432.SCE1572_10845	6.259e-230	731.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2YXPN@29|Myxococcales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
LZS3_k127_7782346_2	511062.GU3_12000	3.375e-125	415.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria,1Y586@135624|Aeromonadales	135624|Aeromonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.113	ko:K12256	ko00330,ko01100,map00330,map01100	-	R08714	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_7782346_1	1192034.CAP_2487	1.123e-135	444.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,42UMU@68525|delta/epsilon subdivisions,2WQA5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
LZS3_k127_7794048_1	1131269.AQVV01000017_gene1971	3.41e-30	132.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cytochrom_C
LZS3_k127_7794048_0	1125863.JAFN01000001_gene2661	9.46e-33	132.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS3_k127_7794048_2	1123261.AXDW01000009_gene180	3.776e-20	102.0	COG4076@1|root,COG4076@2|Bacteria,1RB85@1224|Proteobacteria,1S2XE@1236|Gammaproteobacteria,1X9U1@135614|Xanthomonadales	135614|Xanthomonadales	S	PRMT5 arginine-N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31,PRMT5_C
LZS3_k127_7794916_3	1042375.AFPL01000022_gene2566	1.768e-12	79.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1RPRP@1236|Gammaproteobacteria,464U8@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG2366 Protein related to penicillin acylase	pac	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
LZS3_k127_7794916_2	525897.Dbac_1126	5.73e-22	101.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WP5S@28221|Deltaproteobacteria,2MC10@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS
LZS3_k127_7794916_0	1396418.BATQ01000178_gene2839	3.976e-105	366.0	COG0180@1|root,COG0180@2|Bacteria,46SA6@74201|Verrucomicrobia,2ITQN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS3_k127_7794916_1	156889.Mmc1_1863	8.542e-43	169.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS3_k127_7802778_0	298654.FraEuI1c_1911	1.134e-165	543.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria,4ETUQ@85013|Frankiales	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS3_k127_7802778_1	1340493.JNIF01000003_gene3120	1.224e-57	216.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
LZS3_k127_7803657_5	573370.DMR_p1_00380	5.478e-16	87.0	2904E@1|root,2ZMUC@2|Bacteria,1P5ZS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7803657_3	156889.Mmc1_0613	6.456e-85	310.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2TRRT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Epimerase,Glycos_transf_2
LZS3_k127_7803657_0	118166.JH976537_gene4476	6.453e-213	672.0	COG1032@1|root,COG1032@2|Bacteria,1G3ZK@1117|Cyanobacteria,1HH76@1150|Oscillatoriales	1117|Cyanobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
LZS3_k127_7803657_1	118166.JH976537_gene4475	7.293e-172	568.0	COG0399@1|root,COG0399@2|Bacteria,1G36Q@1117|Cyanobacteria,1H7A2@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_7803657_2	1210884.HG799466_gene12407	1.198e-162	524.0	COG0022@1|root,COG0022@2|Bacteria,2IYRX@203682|Planctomycetes	203682|Planctomycetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS3_k127_7803657_4	118166.JH976537_gene4474	4.438e-35	137.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1G5IK@1117|Cyanobacteria,1HEEQ@1150|Oscillatoriales	1117|Cyanobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
LZS3_k127_7868204_2	760568.Desku_3024	1.737e-61	223.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,260XQ@186807|Peptococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
LZS3_k127_7868204_3	156889.Mmc1_0246	3.071e-51	187.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
LZS3_k127_7868204_4	1121448.DGI_3287	1.522e-41	160.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2MBIE@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS3_k127_7868204_1	269799.Gmet_0608	2.206e-97	330.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,43TEU@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS3_k127_7868204_5	1050202.KB913024_gene1350	6.338e-28	122.0	COG0647@1|root,COG1051@1|root,COG0647@2|Bacteria,COG1051@2|Bacteria,2GJG6@201174|Actinobacteria	2|Bacteria	G	Belongs to the HAD-like hydrolase superfamily	-	-	3.1.3.41,3.6.1.55	ko:K01101,ko:K03574	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000,ko03400	-	-	-	Hydrolase_6,Hydrolase_like,NUDIX
LZS3_k127_7868204_0	1125863.JAFN01000001_gene910	5.557e-245	769.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
LZS3_k127_7881475_1	31954.BPSP_0768	0.0006818	51.0	COG2304@1|root,COG2304@2|Bacteria,2I2FN@201174|Actinobacteria,4D2UT@85004|Bifidobacteriales	201174|Actinobacteria	Q	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	Cna_B,FctA,VWA,VWA_2
LZS3_k127_7881475_0	1232437.KL662010_gene1640	3.579e-14	85.0	COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2MN1B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7881936_2	1144275.COCOR_03204	2.413e-06	56.0	COG3031@1|root,COG3031@2|Bacteria,1RFDB@1224|Proteobacteria,42WP0@68525|delta/epsilon subdivisions,2X6P7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	General secretion pathway protein C	-	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
LZS3_k127_7881936_1	1219049.SP5_089_00160	3.501e-12	78.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2U17R@28211|Alphaproteobacteria,2K18P@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OmpA
LZS3_k127_7881936_0	342113.DM82_5997	1.942e-73	252.0	COG0220@1|root,COG0220@2|Bacteria,1QTX5@1224|Proteobacteria,2WH0A@28216|Betaproteobacteria,1K3DS@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
LZS3_k127_7891435_0	1116472.MGMO_162c00110	4.411e-69	256.0	2A2RR@1|root,30R50@2|Bacteria,1N915@1224|Proteobacteria,1SJ4K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alginate export	-	-	-	ko:K16081	-	-	-	-	ko00000,ko02000	1.B.13.1	-	-	Alginate_exp
LZS3_k127_7891435_1	1121920.AUAU01000004_gene915	1.069e-32	134.0	COG2771@1|root,COG2771@2|Bacteria	2|Bacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
LZS3_k127_7903046_0	1047013.AQSP01000106_gene1773	2.408e-45	182.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
LZS3_k127_7910111_2	1385515.N791_12100	1.277e-59	212.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1X4AQ@135614|Xanthomonadales	135614|Xanthomonadales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
LZS3_k127_7910111_3	465541.ATCJ01000005_gene7212	6.95e-39	152.0	COG0454@1|root,COG1024@1|root,COG0456@2|Bacteria,COG1024@2|Bacteria,2I9Y3@201174|Actinobacteria	201174|Actinobacteria	K	histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS3_k127_7910111_1	1410620.SHLA_25c000620	8.812e-77	280.0	COG0673@1|root,COG0673@2|Bacteria,1PHV2@1224|Proteobacteria,2V8E5@28211|Alphaproteobacteria,4BJ04@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_7910111_4	502025.Hoch_3156	9.952e-27	124.0	2E13Z@1|root,32WJ8@2|Bacteria,1NYI6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7910111_7	452637.Oter_1519	3.8e-11	70.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
LZS3_k127_7910111_6	1173264.KI913949_gene116	3.643e-16	91.0	COG4276@1|root,COG4276@2|Bacteria,1G939@1117|Cyanobacteria,1HCVY@1150|Oscillatoriales	1117|Cyanobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7910111_0	1384056.N787_03315	4.231e-145	471.0	COG2755@1|root,COG2755@2|Bacteria,1NRYP@1224|Proteobacteria,1RWGJ@1236|Gammaproteobacteria,1X3SX@135614|Xanthomonadales	135614|Xanthomonadales	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7910111_5	378806.STAUR_4449	1.03e-20	96.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase,HATPase_c,HisKA,Response_reg
LZS3_k127_792698_2	391625.PPSIR1_23549	1.125e-27	121.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42Z9H@68525|delta/epsilon subdivisions,2WUIK@28221|Deltaproteobacteria,2YUAX@29|Myxococcales	28221|Deltaproteobacteria	K	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
LZS3_k127_792698_1	1278307.KB906967_gene2425	2.416e-28	123.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	yfdE	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_7935920_0	909663.KI867150_gene2934	8.703e-55	213.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MR1G@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
LZS3_k127_7946308_0	391625.PPSIR1_05638	2.414e-137	456.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2YUHB@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
LZS3_k127_7946308_2	469383.Cwoe_1576	2.001e-10	74.0	COG4770@1|root,COG4770@2|Bacteria,2I2DF@201174|Actinobacteria	201174|Actinobacteria	I	biotin lipoyl attachment domain-containing protein	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
LZS3_k127_7946308_3	369723.Strop_1353	3.182e-08	65.0	COG3393@1|root,COG3393@2|Bacteria,2GMD2@201174|Actinobacteria,4D8PZ@85008|Micromonosporales	201174|Actinobacteria	S	Gcn5-related n-acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,DUF4081,FR47
LZS3_k127_7946308_1	1254432.SCE1572_17640	1.265e-87	298.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_7946308_4	880072.Desac_1025	0.0001851	48.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2MR0U@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_7951314_0	1121033.AUCF01000003_gene3110	4.156e-259	840.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2JPCA@204441|Rhodospirillales	204441|Rhodospirillales	E	NAD-specific glutamate dehydrogenase	gdhA	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
LZS3_k127_7957168_3	368408.Tpen_1195	1.469e-06	53.0	COG2120@1|root,arCOG03460@2157|Archaea,2XQXY@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM LmbE family protein	-	-	-	ko:K22408	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
LZS3_k127_7957168_1	395019.Bmul_1434	5.631e-111	370.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VN57@28216|Betaproteobacteria,1K0T4@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Pfam Dehydrogenase E1 component	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
LZS3_k127_7957168_0	1295642.H839_05929	3.274e-123	403.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli,1WFNM@129337|Geobacillus	91061|Bacilli	C	Transketolase, pyrimidine binding domain	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS3_k127_7957168_2	945021.TEH_01240	2.795e-10	73.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli,4B0T0@81852|Enterococcaceae	91061|Bacilli	C	e3 binding domain	acoC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS3_k127_7961183_2	215803.DB30_2139	1.389e-53	201.0	COG2267@1|root,COG2267@2|Bacteria,1RJ4X@1224|Proteobacteria,42WRI@68525|delta/epsilon subdivisions,2WRZ1@28221|Deltaproteobacteria,2YWGU@29|Myxococcales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
LZS3_k127_7961183_0	1313172.YM304_13350	9.136e-179	576.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria	201174|Actinobacteria	Q	dioxygenase	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
LZS3_k127_7961183_3	215803.DB30_6542	6.719e-39	154.0	COG0500@1|root,COG2226@2|Bacteria,1RC36@1224|Proteobacteria,42UDA@68525|delta/epsilon subdivisions,2WQHW@28221|Deltaproteobacteria,2YV8X@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS3_k127_7961183_1	1333998.M2A_1441	1.238e-85	299.0	COG2128@1|root,COG2128@2|Bacteria,1PMH5@1224|Proteobacteria,2TVAY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS3_k127_7965985_1	368407.Memar_0814	6.587e-58	225.0	COG1108@1|root,arCOG01006@2157|Archaea,2XTNB@28890|Euryarchaeota,2N9BQ@224756|Methanomicrobia	224756|Methanomicrobia	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	iAF692.Mbar_A0996	ABC-3
LZS3_k127_7965985_0	1148.1652187	5.841e-85	299.0	COG1121@1|root,COG1121@2|Bacteria,1G2EJ@1117|Cyanobacteria,1H6B7@1142|Synechocystis	1117|Cyanobacteria	P	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
LZS3_k127_7965985_2	584708.Apau_0163	6.739e-35	143.0	COG0803@1|root,COG0803@2|Bacteria,3TB3X@508458|Synergistetes	508458|Synergistetes	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
LZS3_k127_7970802_1	1192034.CAP_6174	8.905e-61	216.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YX2C@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS3_k127_7970802_3	518766.Rmar_2743	2.4e-47	191.0	COG0438@1|root,COG0438@2|Bacteria,4PB7A@976|Bacteroidetes,1FK5B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
LZS3_k127_7970802_4	290397.Adeh_0078	4.059e-35	153.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7970802_2	1333998.M2A_2590	1.193e-47	196.0	2C6CV@1|root,33W8F@2|Bacteria,1RM05@1224|Proteobacteria,2U9CX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7970802_0	402881.Plav_0360	1.473e-267	833.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,1JQ85@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase,Sulfatase_C
LZS3_k127_7970802_5	1122223.KB890687_gene2612	4.578e-35	145.0	COG0384@1|root,COG0384@2|Bacteria,1WJW5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
LZS3_k127_7983089_0	1234595.C725_1311	3.967e-147	479.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,4BPJW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
LZS3_k127_7983089_1	1286093.C266_08540	0.0004455	46.0	COG1605@1|root,COG1605@2|Bacteria,1N4I1@1224|Proteobacteria,2WG3Z@28216|Betaproteobacteria,1KG1T@119060|Burkholderiaceae	28216|Betaproteobacteria	M	chorismate mutase	-	-	5.4.99.5	ko:K04093	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
LZS3_k127_7998050_8	345341.KUTG_08461	4.435e-31	125.0	COG3415@1|root,COG3415@2|Bacteria,2I2W7@201174|Actinobacteria,4EE1Z@85010|Pseudonocardiales	201174|Actinobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
LZS3_k127_7998050_3	765911.Thivi_0637	7.859e-70	269.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,1RNV1@1236|Gammaproteobacteria,1X2HJ@135613|Chromatiales	135613|Chromatiales	I	acyl-CoA dehydrogenase	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N,AcylCoA_dehyd_C
LZS3_k127_7998050_6	1125863.JAFN01000001_gene2355	1.084e-50	196.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1PFJ7@1224|Proteobacteria,42WVE@68525|delta/epsilon subdivisions	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7998050_2	1313172.YM304_15130	9.419e-111	370.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_7998050_0	685727.REQ_15410	1.216e-131	432.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria,4FZEY@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_7998050_7	1267535.KB906767_gene3861	6.81e-34	140.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
LZS3_k127_7998050_11	290397.Adeh_0078	3.495e-12	77.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7998050_1	450851.PHZ_c2788	2.066e-122	411.0	COG0477@1|root,COG0477@2|Bacteria,1QWSX@1224|Proteobacteria,2TX4I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Sugar (and other) transporter	MA20_07500	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
LZS3_k127_7998050_10	404589.Anae109_3600	3.328e-25	110.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2YW4G@29|Myxococcales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
LZS3_k127_7998050_5	448385.sce0673	1.234e-60	232.0	COG0657@1|root,COG0657@2|Bacteria,1MVRE@1224|Proteobacteria,42XSE@68525|delta/epsilon subdivisions,2WTGG@28221|Deltaproteobacteria,2YYH0@29|Myxococcales	28221|Deltaproteobacteria	I	Pectinacetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	PAE
LZS3_k127_7998050_4	404589.Anae109_3016	6.308e-69	246.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS3_k127_7998050_9	1366050.N234_32130	4.38e-30	123.0	COG0457@1|root,COG0457@2|Bacteria,1NP3J@1224|Proteobacteria,2WF80@28216|Betaproteobacteria,1KHZG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_11,TPR_16,TPR_6,TPR_8
LZS3_k127_8051221_0	886293.Sinac_7280	6.13e-108	359.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_8051221_1	1382306.JNIM01000001_gene3774	1.482e-102	351.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
LZS3_k127_8051221_2	1340493.JNIF01000003_gene1791	1.102e-84	289.0	COG1606@1|root,COG1606@2|Bacteria,3Y30C@57723|Acidobacteria	57723|Acidobacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
LZS3_k127_808644_0	391625.PPSIR1_34807	6.886e-150	487.0	COG1752@1|root,COG1752@2|Bacteria,1R7RX@1224|Proteobacteria,4379P@68525|delta/epsilon subdivisions,2X9XU@28221|Deltaproteobacteria,2Z1Y1@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
LZS3_k127_808644_2	358396.C445_14699	2.669e-42	165.0	COG3332@1|root,arCOG06429@2157|Archaea,2XU65@28890|Euryarchaeota,23UCP@183963|Halobacteria	183963|Halobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
LZS3_k127_808644_1	498761.HM1_2748	5.08e-48	181.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS3_k127_8088861_1	59538.XP_005964126.1	9.233e-05	54.0	COG0329@1|root,2QWNS@2759|Eukaryota,399HY@33154|Opisthokonta,3BGNT@33208|Metazoa,3CUM9@33213|Bilateria	33208|Metazoa	E	4-hydroxy-2-oxoglutarate aldolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
LZS3_k127_8088861_0	1245471.PCA10_23420	2.698e-72	259.0	COG3391@1|root,COG3391@2|Bacteria,1R8X0@1224|Proteobacteria,1S1R2@1236|Gammaproteobacteria,1YFM8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Methylamine dehydrogenase heavy chain (MADH)	mauB	-	1.4.9.1	ko:K15229	ko00680,ko01120,map00680,map01120	-	R00606	RC00189	ko00000,ko00001,ko01000	-	-	-	Me-amine-dh_H
LZS3_k127_8095884_0	448385.sce2503	2.279e-203	643.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YUB7@29|Myxococcales	28221|Deltaproteobacteria	KL	Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
LZS3_k127_8122994_1	518766.Rmar_0923	8.555e-276	860.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,1FIM5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EI	ArgK protein	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
LZS3_k127_8122994_0	414684.RC1_3119	5e-324	1005.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JP9C@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
LZS3_k127_8122994_5	414684.RC1_3097	8.36e-98	335.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,2JP84@204441|Rhodospirillales	204441|Rhodospirillales	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
LZS3_k127_8122994_8	290397.Adeh_4322	9.826e-64	227.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,42R57@68525|delta/epsilon subdivisions,2WN5Y@28221|Deltaproteobacteria,2YUYK@29|Myxococcales	28221|Deltaproteobacteria	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
LZS3_k127_8122994_2	1125863.JAFN01000001_gene29	1.228e-179	573.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
LZS3_k127_8122994_3	326427.Cagg_0759	4.412e-119	392.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,374WI@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
LZS3_k127_8122994_7	215803.DB30_5420	1.024e-79	295.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,42QBK@68525|delta/epsilon subdivisions,2WITZ@28221|Deltaproteobacteria,2YW16@29|Myxococcales	28221|Deltaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
LZS3_k127_8122994_4	887898.HMPREF0551_0176	3.059e-116	392.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,1K092@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
LZS3_k127_8122994_6	290397.Adeh_0571	2.368e-87	312.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1P2AZ@1224|Proteobacteria,4312R@68525|delta/epsilon subdivisions,2WWR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS3_k127_8122994_9	1297742.A176_02040	3.04e-50	194.0	COG0745@1|root,COG0745@2|Bacteria,1NQ8U@1224|Proteobacteria,42QWX@68525|delta/epsilon subdivisions,2WN80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
LZS3_k127_8136819_1	234621.RER_58640	1.112e-22	113.0	COG0596@1|root,COG0596@2|Bacteria,2I9EM@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
LZS3_k127_8136819_2	243090.RB9985	2.302e-05	54.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8136819_0	522373.Smlt1599	1.63e-69	241.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,1X3TB@135614|Xanthomonadales	135614|Xanthomonadales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS3_k127_8166796_0	765912.Thimo_3089	6.841e-25	122.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1WX1E@135613|Chromatiales	135613|Chromatiales	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
LZS3_k127_8166865_0	404589.Anae109_0596	7.502e-87	290.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,42MJI@68525|delta/epsilon subdivisions,2WJQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	6-phosphogluconate dehydrogenase (decarboxylating)	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2620	6PGD,NAD_binding_2
LZS3_k127_8166865_1	247634.GPB2148_549	4.701e-18	96.0	COG1073@1|root,COG1073@2|Bacteria,1PQAX@1224|Proteobacteria,1S02C@1236|Gammaproteobacteria,1J81R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF2048
LZS3_k127_8167605_0	561175.KB894094_gene2054	7.356e-107	361.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4EFPE@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
LZS3_k127_8167605_1	882083.SacmaDRAFT_3837	2.569e-81	297.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4E83P@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	hdhA	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
LZS3_k127_8169220_0	1173026.Glo7428_1706	5.571e-150	492.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria	1117|Cyanobacteria	S	tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
LZS3_k127_8169220_1	1123020.AUIE01000033_gene3474	3.386e-39	160.0	COG2094@1|root,COG2094@2|Bacteria,1R95J@1224|Proteobacteria,1T0WF@1236|Gammaproteobacteria,1YE59@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
LZS3_k127_8207392_0	1125863.JAFN01000001_gene1090	2.045e-79	283.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
LZS3_k127_8207392_1	1278309.KB907107_gene1655	7.202e-26	124.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1XH8Y@135619|Oceanospirillales	135619|Oceanospirillales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
LZS3_k127_8211272_3	1401065.HMPREF2130_08885	1.381e-08	57.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,3T1J5@506|Alcaligenaceae	28216|Betaproteobacteria	DM	Lysin motif	nlpD_2	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
LZS3_k127_8211272_1	2423.NA23_0207425	1.088e-44	173.0	COG0639@1|root,COG0639@2|Bacteria,2GCVZ@200918|Thermotogae	200918|Thermotogae	T	PFAM metallophosphoesterase	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
LZS3_k127_8211272_0	686340.Metal_1936	1.159e-84	304.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1XE4Q@135618|Methylococcales	135618|Methylococcales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
LZS3_k127_8211272_2	94624.Bpet4321	4.78e-31	130.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,3T1QF@506|Alcaligenaceae	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
LZS3_k127_8220838_1	1449976.KALB_2441	9.652e-110	363.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4E07A@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_8220838_0	1297742.A176_02167	1.99e-121	403.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS3_k127_8266910_0	479434.Sthe_2867	4.517e-39	153.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi,27Y50@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_8266910_1	1123279.ATUS01000006_gene3453	1.101e-10	64.0	COG3119@1|root,COG3119@2|Bacteria,1MX3Z@1224|Proteobacteria,1RSAF@1236|Gammaproteobacteria,1J9C8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_8272329_0	1234664.AMRO01000028_gene1514	6.813e-117	400.0	COG2272@1|root,COG2272@2|Bacteria,1UXY5@1239|Firmicutes,4HCKV@91061|Bacilli,1WEY8@129337|Geobacillus	91061|Bacilli	I	Carboxylesterase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
LZS3_k127_8272329_3	1449069.JMLO01000031_gene280	4.406e-26	125.0	COG4308@1|root,COG4308@2|Bacteria,2IP4X@201174|Actinobacteria,4G2E2@85025|Nocardiaceae	201174|Actinobacteria	Q	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	LEH
LZS3_k127_8272329_1	1292034.OR37_03396	4.643e-103	357.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,2TSUK@28211|Alphaproteobacteria,2KFTH@204458|Caulobacterales	204458|Caulobacterales	E	PFAM Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
LZS3_k127_8272329_2	357808.RoseRS_3480	5.652e-103	342.0	COG1472@1|root,COG1472@2|Bacteria,2G639@200795|Chloroflexi,374XN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
LZS3_k127_8282593_0	1173021.ALWA01000028_gene1996	6.513e-44	167.0	COG4276@1|root,COG4276@2|Bacteria,1G60I@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
LZS3_k127_8322947_1	706587.Desti_3189	6.614e-185	590.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42MBP@68525|delta/epsilon subdivisions,2WJAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	lpdA-4	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS3_k127_8322947_2	1254432.SCE1572_04375	3.785e-44	169.0	COG0467@1|root,COG0467@2|Bacteria,1RFBT@1224|Proteobacteria,42QWP@68525|delta/epsilon subdivisions,2WMB2@28221|Deltaproteobacteria,2YTTP@29|Myxococcales	28221|Deltaproteobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8322947_0	1125863.JAFN01000001_gene1028	2.514e-320	993.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42NDG@68525|delta/epsilon subdivisions,2WKYU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS3_k127_8347934_0	1137799.GZ78_22325	4.734e-202	648.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria,1XMWY@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
LZS3_k127_8347934_2	379066.GAU_3713	1.172e-07	59.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	Fer4,HTH_3,HTH_31
LZS3_k127_8347934_3	684949.ATTJ01000001_gene686	0.000111	51.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
LZS3_k127_8347934_1	509191.AEDB02000075_gene2832	3.533e-34	148.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_8348272_0	1348657.M622_02760	1.92e-225	711.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS3_k127_8348272_4	1348657.M622_02785	1.67e-145	467.0	COG2159@1|root,COG2159@2|Bacteria,1PUZA@1224|Proteobacteria,2VXX6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_8348272_7	290397.Adeh_1738	1.891e-42	177.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH,HNH_4
LZS3_k127_8348272_10	545264.KB898745_gene1354	3.133e-23	102.0	2DNRM@1|root,32YT2@2|Bacteria,1N8BS@1224|Proteobacteria,1T0VB@1236|Gammaproteobacteria,1WZ7K@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
LZS3_k127_8348272_8	83406.HDN1F_03130	9.597e-27	110.0	2C5EY@1|root,32YQJ@2|Bacteria,1N8K7@1224|Proteobacteria,1SDU6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
LZS3_k127_8348272_9	67257.JODR01000006_gene2528	5.135e-24	118.0	COG3467@1|root,COG3467@2|Bacteria,2IIAS@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
LZS3_k127_8348272_5	247634.GPB2148_3742	8.682e-116	385.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,1RNB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA transferases carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_8348272_1	1348657.M622_02730	4.559e-176	564.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VJ3K@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	2.8.3.15	ko:K07544	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
LZS3_k127_8348272_2	1348657.M622_02725	4.647e-157	526.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VN0B@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
LZS3_k127_8348272_3	1348657.M622_02900	8.265e-151	484.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2VQG6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
LZS3_k127_8348272_6	1348657.M622_02910	6.003e-70	248.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	ygcR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
LZS3_k127_8351713_0	1121013.P873_11225	3.922e-83	288.0	COG3975@1|root,COG3975@2|Bacteria,1QX25@1224|Proteobacteria,1RWD8@1236|Gammaproteobacteria,1X9T6@135614|Xanthomonadales	135614|Xanthomonadales	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8351713_2	472759.Nhal_1698	6.76e-06	57.0	29FX1@1|root,34453@2|Bacteria,1P3CX@1224|Proteobacteria,1SVJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8351713_1	257310.BB3268	2.674e-12	78.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,2VU1J@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
LZS3_k127_8359467_5	1235790.C805_00437	3.382e-11	71.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
LZS3_k127_8359467_2	1254432.SCE1572_52465	6.855e-111	365.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,42PMI@68525|delta/epsilon subdivisions,2WN46@28221|Deltaproteobacteria,2YVR3@29|Myxococcales	28221|Deltaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
LZS3_k127_8359467_0	1192034.CAP_2437	4.51e-119	424.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,42M6K@68525|delta/epsilon subdivisions,2WKQC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Required for the activity of the bacterial periplasmic transport system of putrescine	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
LZS3_k127_8359467_3	1192034.CAP_2438	4.898e-93	314.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,42MIJ@68525|delta/epsilon subdivisions,2WJKS@28221|Deltaproteobacteria,2YVFN@29|Myxococcales	28221|Deltaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	potC2	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
LZS3_k127_8359467_1	497964.CfE428DRAFT_2872	2.913e-115	393.0	COG0123@1|root,COG0123@2|Bacteria,46T7E@74201|Verrucomicrobia	74201|Verrucomicrobia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS3_k127_8359467_4	497964.CfE428DRAFT_2873	8.651e-46	177.0	2FED1@1|root,346CU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8367906_3	292459.STH2818	1.29e-13	73.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
LZS3_k127_8367906_1	1219045.BV98_003257	1.525e-42	161.0	COG5517@1|root,COG5517@2|Bacteria,1RGXR@1224|Proteobacteria,2U8B0@28211|Alphaproteobacteria,2K4PY@204457|Sphingomonadales	204457|Sphingomonadales	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
LZS3_k127_8367906_0	1380386.JIAW01000004_gene209	3.003e-59	221.0	COG1335@1|root,COG1335@2|Bacteria,2I81Y@201174|Actinobacteria,2355H@1762|Mycobacteriaceae	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
LZS3_k127_8367906_2	883.DvMF_0195	7.834e-27	114.0	COG0724@1|root,COG0724@2|Bacteria,1N0P8@1224|Proteobacteria,43B6G@68525|delta/epsilon subdivisions,2WQ1E@28221|Deltaproteobacteria,2MH3Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_8376610_0	338963.Pcar_1946	8.491e-66	244.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43TY0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
LZS3_k127_8376610_1	1232410.KI421421_gene3663	3.051e-46	178.0	COG1192@1|root,COG1192@2|Bacteria,1NPCB@1224|Proteobacteria,42Y7J@68525|delta/epsilon subdivisions,2WUHN@28221|Deltaproteobacteria,43T7Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
LZS3_k127_840410_2	765420.OSCT_0889	1.585e-22	109.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS3_k127_840410_1	1121405.dsmv_1897	1.96e-23	104.0	COG1225@1|root,COG1225@2|Bacteria,1NN23@1224|Proteobacteria,42XJF@68525|delta/epsilon subdivisions,2WTAE@28221|Deltaproteobacteria,2MNXB@213118|Desulfobacterales	28221|Deltaproteobacteria	O	AhpC/TSA antioxidant enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA_2
LZS3_k127_840410_0	886293.Sinac_4737	9.91e-175	561.0	COG1164@1|root,COG1164@2|Bacteria,2IWWZ@203682|Planctomycetes	203682|Planctomycetes	E	oligoendopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
LZS3_k127_8406239_0	338966.Ppro_2604	1.039e-203	649.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,43T3K@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS3_k127_8408038_3	1125701.HMPREF1221_00130	2.828e-08	60.0	COG2334@1|root,COG2334@2|Bacteria,2J750@203691|Spirochaetes	203691|Spirochaetes	S	PFAM Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
LZS3_k127_8408038_0	1160137.KB907307_gene2654	2.318e-156	509.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4FUI3@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_8408038_2	402881.Plav_0485	4.802e-61	225.0	COG0625@1|root,COG0625@2|Bacteria,1R3VG@1224|Proteobacteria,2U50H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0625 Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
LZS3_k127_8408038_1	2055.JNXA01000020_gene3646	8.892e-64	234.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4GACK@85026|Gordoniaceae	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.8.1.20	ko:K22347	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
LZS3_k127_841140_3	1254432.SCE1572_36750	6.234e-19	92.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	glsA	GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	CBS,Glutaminase,MS_channel,STAS,cNMP_binding
LZS3_k127_841140_5	216142.LT40_12310	7.875e-05	48.0	2EGUJ@1|root,33AKQ@2|Bacteria	2|Bacteria	S	Chromosome partitioning protein ParA	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
LZS3_k127_841140_4	472759.Nhal_3598	1.426e-10	68.0	2EHHF@1|root,33B9C@2|Bacteria,1NM2H@1224|Proteobacteria,1SGI5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_841140_0	1229780.BN381_290075	1.031e-110	377.0	COG0208@1|root,COG0208@2|Bacteria	2|Bacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	Ald_deCOase
LZS3_k127_841140_1	1229780.BN381_290074	3.253e-78	270.0	COG0208@1|root,COG0208@2|Bacteria	2|Bacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	-	-	-	-	-	-	-	-	-	-	Ald_deCOase
LZS3_k127_8414892_0	1073999.BN137_1081	2.727e-107	373.0	COG1541@1|root,COG1541@2|Bacteria,1NR5G@1224|Proteobacteria,1RRCG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	acyl-protein synthetase	-	-	6.2.1.19	ko:K06046	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	LuxE
LZS3_k127_8414892_1	1123487.KB892839_gene117	6.038e-91	309.0	COG0318@1|root,COG0318@2|Bacteria,1MWJ6@1224|Proteobacteria,2VJVE@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
LZS3_k127_842075_1	1242864.D187_005496	6.991e-78	276.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,42UK8@68525|delta/epsilon subdivisions,2WQG7@28221|Deltaproteobacteria,2Z0U2@29|Myxococcales	28221|Deltaproteobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	2.4.1.310	ko:K16444	ko01055,map01055	-	-	-	ko00000,ko00001,ko01000	-	GT1	-	Glyco_transf_28,UDPGT
LZS3_k127_842075_4	1487953.JMKF01000074_gene3690	0.0002028	49.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G1PT@1117|Cyanobacteria,1H7NV@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,PAS,PAS_8,PAS_9
LZS3_k127_842075_2	977880.RALTA_A2293	2.555e-32	145.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,1K1R1@119060|Burkholderiaceae	28216|Betaproteobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa2	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS3_k127_842075_0	1396141.BATP01000003_gene5111	2.661e-103	351.0	COG0745@1|root,COG1235@1|root,COG2203@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,COG2203@2|Bacteria,46UKB@74201|Verrucomicrobia,2IVU2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Response_reg
LZS3_k127_842075_3	1196323.ALKF01000202_gene3929	2.122e-26	128.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1UYB2@1239|Firmicutes,4HIMD@91061|Bacilli,26TDP@186822|Paenibacillaceae	91061|Bacilli	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
LZS3_k127_8424590_0	331869.BAL199_16228	2.587e-257	805.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2TT3C@28211|Alphaproteobacteria,4BPZW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	GMC oxidoreductase	MA20_17575	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
LZS3_k127_8440893_2	561175.KB894097_gene277	7.343e-59	215.0	COG3268@1|root,COG3268@2|Bacteria,2GNGH@201174|Actinobacteria,4EG5H@85012|Streptosporangiales	201174|Actinobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
LZS3_k127_8440893_1	1229780.BN381_10279	7.071e-106	379.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria	201174|Actinobacteria	Q	diacylglycerol O-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
LZS3_k127_8440893_0	648757.Rvan_2904	7.969e-152	505.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	dioxygenase	-	-	1.13.11.82	ko:K11159,ko:K21822	-	-	-	-	ko00000,ko01000	-	-	-	RPE65
LZS3_k127_8440893_3	215803.DB30_2464	4.83e-16	86.0	COG1752@1|root,COG1752@2|Bacteria,1PEH4@1224|Proteobacteria,42XKH@68525|delta/epsilon subdivisions,2WTA6@28221|Deltaproteobacteria,2YUHG@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS3_k127_8487059_1	1097668.BYI23_A012230	1.613e-32	131.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,1K2RJ@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
LZS3_k127_8487059_2	330214.NIDE4120	3.57e-21	103.0	COG0802@1|root,COG0802@2|Bacteria,3J1AZ@40117|Nitrospirae	40117|Nitrospirae	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
LZS3_k127_8487059_0	1125863.JAFN01000001_gene2152	8.245e-148	479.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
LZS3_k127_8499198_5	1206743.BAGM01000027_gene2997	6.384e-06	57.0	COG1960@1|root,COG1960@2|Bacteria,2HY6H@201174|Actinobacteria,4FVKT@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE21	-	-	ko:K00257	-	-	R04547,R04592	RC01942	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_8499198_4	1440774.Y900_009765	5.275e-19	96.0	COG1309@1|root,COG1309@2|Bacteria,2IC2M@201174|Actinobacteria,238AC@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_8499198_2	1245471.PCA10_29480	7.234e-111	371.0	COG1960@1|root,COG1960@2|Bacteria,1P7WH@1224|Proteobacteria,1RNZQ@1236|Gammaproteobacteria,1YHJ5@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
LZS3_k127_8499198_3	1348657.M622_04425	1.045e-79	299.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS3_k127_8499198_1	1245471.PCA10_29470	7.845e-139	466.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,1S0KG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_8499198_0	1348657.M622_04415	4.099e-178	570.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2VR64@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_8500535_1	997346.HMPREF9374_0159	1.07e-262	825.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,27BJQ@186824|Thermoactinomycetaceae	91061|Bacilli	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
LZS3_k127_8500535_0	1056820.KB900637_gene164	1.575e-301	964.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,2PNCX@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_5_12_2,Cytochrome_CBB3,GSDH,He_PIG,PA14
LZS3_k127_8522682_0	1121028.ARQE01000004_gene1210	2.123e-93	311.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,2PKIR@255475|Aurantimonadaceae	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	MA20_25935	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
LZS3_k127_8522682_2	398767.Glov_1520	4.83e-27	119.0	COG2519@1|root,COG3119@1|root,COG2519@2|Bacteria,COG3119@2|Bacteria,1NIZU@1224|Proteobacteria,42Z5U@68525|delta/epsilon subdivisions,2WU2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_8522682_1	290397.Adeh_2975	3.422e-80	289.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PNX@68525|delta/epsilon subdivisions,2WK8F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
LZS3_k127_8539920_3	1048339.KB913029_gene3082	1.378e-11	78.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,4EU4V@85013|Frankiales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_8539920_1	1197906.CAJQ02000053_gene4284	8.245e-84	289.0	COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,2TTQ1@28211|Alphaproteobacteria,3JT0H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	MA20_19270	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_8539920_0	1123320.KB889562_gene6740	7.479e-87	294.0	COG1024@1|root,COG1024@2|Bacteria,2IAFJ@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_8539920_2	1341679.P253_02322	3.708e-17	81.0	COG3465@1|root,COG3465@2|Bacteria,1R0IQ@1224|Proteobacteria,1T535@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
LZS3_k127_8568343_0	2074.JNYD01000001_gene5846	3.027e-109	387.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2H57H@201174|Actinobacteria,4EF5W@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
LZS3_k127_8568770_0	1394178.AWOO02000073_gene2274	3.67e-30	136.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EGFA@85012|Streptosporangiales	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS3_k127_8569576_1	429009.Adeg_1160	9.641e-88	308.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42EK5@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
LZS3_k127_8569576_2	497964.CfE428DRAFT_0598	1.069e-66	253.0	COG0512@1|root,COG0512@2|Bacteria,46SN1@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	PFAM glutamine amidotransferase class-I	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS3_k127_8569576_0	243231.GSU2383	2.368e-157	548.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43TZF@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
LZS3_k127_8569576_4	909663.KI867150_gene2384	4.81e-40	171.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,2MQEF@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
LZS3_k127_8569576_6	290397.Adeh_1256	4.842e-21	106.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2WT4M@28221|Deltaproteobacteria,2YVRK@29|Myxococcales	28221|Deltaproteobacteria	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
LZS3_k127_8569576_5	1267535.KB906767_gene4961	1.34e-24	119.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
LZS3_k127_8569576_3	266779.Meso_1771	6.065e-57	209.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,43IUX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
LZS3_k127_8569576_7	1283300.ATXB01000001_gene259	1.817e-05	50.0	2DGQ2@1|root,2ZWWE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8571342_1	1121935.AQXX01000064_gene3298	2.539e-122	404.0	COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,1RRAQ@1236|Gammaproteobacteria,1XKF1@135619|Oceanospirillales	135619|Oceanospirillales	I	alpha/beta hydrolase fold	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
LZS3_k127_8571342_4	96561.Dole_2248	1.07e-89	304.0	COG1024@1|root,COG1024@2|Bacteria,1MVPQ@1224|Proteobacteria,42ZK8@68525|delta/epsilon subdivisions,2WUST@28221|Deltaproteobacteria,2MNI2@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_8571342_0	1448389.BAVQ01000090_gene2088	2.437e-122	417.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_8571342_2	1194972.MVAC_11087	4.039e-99	337.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,234N3@1762|Mycobacteriaceae	201174|Actinobacteria	C	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
LZS3_k127_8571342_6	537972.ABQU01000030_gene424	3.188e-05	47.0	2A4CB@1|root,30SXZ@2|Bacteria,1PCGS@1224|Proteobacteria,42W82@68525|delta/epsilon subdivisions,2YQMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8571342_8	565045.NOR51B_2339	0.00024	55.0	COG1361@1|root,COG2374@1|root,COG4409@1|root,COG4886@1|root,COG1361@2|Bacteria,COG2374@2|Bacteria,COG4409@2|Bacteria,COG4886@2|Bacteria,1R0YK@1224|Proteobacteria,1T4RP@1236|Gammaproteobacteria	2|Bacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Big_5,LRR_5,LTD,P_proprotein,Peptidase_S8,TSP_3
LZS3_k127_8571342_3	335543.Sfum_3567	1.79e-93	337.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,2MSID@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS3_k127_8571342_5	316067.Geob_3174	1.611e-59	231.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,43T10@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
LZS3_k127_8579061_4	269799.Gmet_3410	5.56e-14	80.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,43V2P@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
LZS3_k127_8579061_3	439235.Dalk_3629	2.325e-32	140.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,2MJKI@213118|Desulfobacterales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
LZS3_k127_8579061_0	316067.Geob_0449	6.047e-230	722.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,43T4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS3_k127_8579061_2	404589.Anae109_4496	1.164e-66	237.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2YUV1@29|Myxococcales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
LZS3_k127_8579061_1	316067.Geob_0447	3.022e-156	498.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,43TRP@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS3_k127_8585719_1	216594.MMAR_3470	7.152e-61	214.0	COG1028@1|root,COG1028@2|Bacteria,2GM3I@201174|Actinobacteria,2368D@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_8585719_0	1229780.BN381_360022	2.641e-99	337.0	COG1680@1|root,COG1680@2|Bacteria,2HEWU@201174|Actinobacteria,3UXIA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_8585719_2	246197.MXAN_5515	1.062e-10	64.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WM9S@28221|Deltaproteobacteria,2YZVS@29|Myxococcales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
LZS3_k127_8596215_1	1207076.ALAT01000204_gene1776	4.095e-25	123.0	COG2188@1|root,COG3746@1|root,COG2188@2|Bacteria,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria,1T5CM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
LZS3_k127_8596215_0	1114970.PSF113_2623	6.826e-26	119.0	COG2831@1|root,COG2831@2|Bacteria,1PRBP@1224|Proteobacteria,1RZKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
LZS3_k127_8600088_0	760568.Desku_1838	1.068e-113	382.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
LZS3_k127_8603130_1	345341.KUTG_00417	2.172e-29	131.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_35,CBM_6
LZS3_k127_8603130_0	1303518.CCALI_00206	4.536e-57	222.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	-	-	2.7.1.168,2.7.1.36	ko:K00869,ko:K07031	ko00540,ko00900,ko01100,ko01110,ko01130,ko04146,map00540,map00900,map01100,map01110,map01130,map04146	M00095	R02245,R09770	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS3_k127_8617614_1	666685.R2APBS1_3632	1.827e-165	537.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,1RNG8@1236|Gammaproteobacteria,1X4AG@135614|Xanthomonadales	135614|Xanthomonadales	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
LZS3_k127_8617614_2	1282876.BAOK01000001_gene2767	5.183e-94	322.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_8617614_6	1227457.C451_15508	1.169e-22	114.0	arCOG06256@1|root,arCOG06256@2157|Archaea,2XUA8@28890|Euryarchaeota,23TAD@183963|Halobacteria	183963|Halobacteria	S	phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
LZS3_k127_8617614_0	321332.CYB_0327	6.836e-223	698.0	COG0065@1|root,COG0065@2|Bacteria,1G1J0@1117|Cyanobacteria,1GZ9E@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
LZS3_k127_8617614_4	671143.DAMO_0873	1.478e-61	238.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
LZS3_k127_8617614_3	760568.Desku_1234	3.928e-66	246.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,26121@186807|Peptococcaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
LZS3_k127_8617614_5	1282876.BAOK01000001_gene2732	4.388e-28	132.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,2U0NZ@28211|Alphaproteobacteria,4BSP2@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1499)	MA20_07395	-	-	-	-	-	-	-	-	-	-	-	DUF1499
LZS3_k127_8629570_0	266117.Rxyl_0743	2.588e-134	440.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CPTD@84995|Rubrobacteria	84995|Rubrobacteria	HP	UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
LZS3_k127_8630518_0	667014.Thein_0074	1.647e-177	579.0	COG1109@1|root,COG1109@2|Bacteria,2GGQT@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS3_k127_8630518_1	1307759.JOMJ01000003_gene503	1.895e-18	94.0	COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,2MC38@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
LZS3_k127_8632336_0	1121405.dsmv_1858	5.814e-245	767.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2MHVD@213118|Desulfobacterales	28221|Deltaproteobacteria	J	TIGRFAM glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
LZS3_k127_8635699_2	43759.JNWK01000083_gene3326	3.902e-125	429.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
LZS3_k127_8635699_0	1394178.AWOO02000005_gene3693	1.691e-173	573.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria,4EHB7@85012|Streptosporangiales	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
LZS3_k127_8635699_1	1278073.MYSTI_04818	5.881e-132	447.0	COG0183@1|root,COG0183@2|Bacteria,1PSXC@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
LZS3_k127_8635699_3	1122609.AUGT01000003_gene2398	4.363e-95	327.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria,4DMZC@85009|Propionibacteriales	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
LZS3_k127_8635699_4	1449355.JQNR01000003_gene511	0.0005673	46.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
LZS3_k127_8635973_3	702113.PP1Y_Mpl2790	4.624e-34	134.0	COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,2TT9T@28211|Alphaproteobacteria,2KCQ7@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
LZS3_k127_8635973_2	1150599.MPHLEI_07534	4.282e-85	299.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,235W7@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_8635973_1	338969.Rfer_1098	1.866e-138	452.0	COG0475@1|root,COG0475@2|Bacteria,1MVGV@1224|Proteobacteria,2VJ0E@28216|Betaproteobacteria,4AEN9@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
LZS3_k127_8635973_4	1123368.AUIS01000001_gene2008	2.18e-16	90.0	COG0271@1|root,COG0271@2|Bacteria,1QCW4@1224|Proteobacteria,1T8PS@1236|Gammaproteobacteria,2ND8D@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Belongs to the BolA IbaG family	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
LZS3_k127_8635973_0	1313172.YM304_21870	6.41e-140	453.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria	201174|Actinobacteria	T	2-nitropropane dioxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
LZS3_k127_863791_0	1206729.BAFZ01000034_gene4934	8.599e-138	451.0	COG0654@1|root,COG0654@2|Bacteria,2GK88@201174|Actinobacteria,4FUR2@85025|Nocardiaceae	201174|Actinobacteria	CH	FAD binding domain	mhpA	-	1.14.13.219,1.14.13.220	ko:K20943,ko:K20944	ko00362,ko01120,map00362,map01120	-	R05249,R11347	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
LZS3_k127_863791_1	1463879.JOHP01000002_gene1742	5.024e-100	334.0	COG0346@1|root,COG0346@2|Bacteria,2GN2E@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_863791_2	207954.MED92_14528	1.222e-93	313.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,1XHXA@135619|Oceanospirillales	135619|Oceanospirillales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
LZS3_k127_8640760_0	42256.RradSPS_2095	7.795e-76	276.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CR6S@84995|Rubrobacteria	84995|Rubrobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
LZS3_k127_8653988_2	83406.HDN1F_09800	1.133e-20	95.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
LZS3_k127_8653988_0	1283300.ATXB01000001_gene1912	3.047e-61	231.0	COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria,1XF6V@135618|Methylococcales	135618|Methylococcales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
LZS3_k127_8653988_1	880073.Calab_0502	2.097e-21	106.0	COG1402@1|root,COG1402@2|Bacteria,2NRF3@2323|unclassified Bacteria	2|Bacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS3_k127_8653988_3	1123320.KB889677_gene2722	1.748e-07	61.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria	201174|Actinobacteria	E	Dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
LZS3_k127_8658236_0	316058.RPB_2657	5.811e-124	406.0	COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria,2TVH8@28211|Alphaproteobacteria,3JS6S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	KR domain	MA20_36825	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_8667638_1	450380.JPSY01000004_gene3047	9.957e-33	130.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,4FNR9@85023|Microbacteriaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
LZS3_k127_8667638_0	697281.Mahau_2374	9.946e-44	174.0	COG2199@1|root,COG3706@2|Bacteria,1VADD@1239|Firmicutes,25E7Q@186801|Clostridia,42J5P@68295|Thermoanaerobacterales	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_9,Response_reg,TPR_8
LZS3_k127_8671613_4	604331.AUHY01000085_gene159	2.329e-05	52.0	COG1708@1|root,COG1708@2|Bacteria,1WKG4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Nucleotidyltransferase domain	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
LZS3_k127_8671613_3	368407.Memar_1589	1.112e-15	84.0	COG2445@1|root,arCOG02109@2157|Archaea,2Y25T@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
LZS3_k127_8671613_2	1238182.C882_1024	1.018e-17	92.0	COG2010@1|root,COG2010@2|Bacteria,1NAGW@1224|Proteobacteria,2UCCK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_8671613_0	219305.MCAG_05011	1.127e-154	512.0	COG1233@1|root,COG1233@2|Bacteria,2GP0A@201174|Actinobacteria,4DENF@85008|Micromonosporales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,FAD_binding_6,Fer2,NAD_binding_1
LZS3_k127_8671613_1	1333998.M2A_2882	9.268e-21	108.0	COG3631@1|root,COG3631@2|Bacteria,1RHRD@1224|Proteobacteria,2UEU1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
LZS3_k127_8680369_8	1206741.BAFX01000050_gene2228	1.154e-09	62.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4FXVR@85025|Nocardiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_8680369_4	1238182.C882_0864	1.064e-67	244.0	COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,2TQX4@28211|Alphaproteobacteria,2JRGJ@204441|Rhodospirillales	204441|Rhodospirillales	S	May be involved in the transport of PQQ or its precursor to the periplasm	pqqB	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
LZS3_k127_8680369_3	66875.JODY01000006_gene2183	2.728e-77	271.0	COG5424@1|root,COG5424@2|Bacteria,2I9SS@201174|Actinobacteria	201174|Actinobacteria	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
LZS3_k127_8680369_1	1121861.KB899919_gene2757	3.472e-108	376.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2TTS5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	biosynthesis protein E	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS3_k127_8680369_2	330214.NIDE0204	1.259e-104	353.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,3J13F@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
LZS3_k127_8680369_0	383372.Rcas_4411	1.813e-132	451.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi,375BT@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
LZS3_k127_8680369_7	504472.Slin_4456	1.034e-18	89.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
LZS3_k127_8680369_6	1283300.ATXB01000001_gene2139	1.116e-20	96.0	COG1598@1|root,COG1598@2|Bacteria,1NPTZ@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8690627_0	1128421.JAGA01000003_gene3323	6.836e-181	584.0	COG1472@1|root,COG1472@2|Bacteria,2NNZB@2323|unclassified Bacteria	2|Bacteria	G	Glycoside hydrolase family 3 domain protein	bxlA	-	3.2.1.21	ko:K05349,ko:K17641	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
LZS3_k127_8690627_1	1116232.AHBF01000116_gene4499	1.747e-21	105.0	COG2755@1|root,COG2755@2|Bacteria,2GP5V@201174|Actinobacteria	201174|Actinobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Ricin_B_lectin
LZS3_k127_8696353_1	1125863.JAFN01000001_gene685	1.795e-65	242.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,43BKJ@68525|delta/epsilon subdivisions,2WIZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_8696353_7	1156937.MFUM_390011	3.92e-23	111.0	COG3288@1|root,COG3288@2|Bacteria,46T7S@74201|Verrucomicrobia,37H24@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
LZS3_k127_8696353_0	234267.Acid_3373	3.402e-181	586.0	COG1282@1|root,COG1282@2|Bacteria,3Y42H@57723|Acidobacteria	57723|Acidobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
LZS3_k127_8696353_3	290397.Adeh_0078	2.06e-33	135.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8696353_6	287.DR97_2190	6.194e-25	109.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,1YGA1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Translation initiation factor	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
LZS3_k127_8696353_4	670487.Ocepr_0311	1.206e-32	137.0	COG1832@1|root,COG1832@2|Bacteria,1WJSJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
LZS3_k127_8696353_2	404589.Anae109_1972	2.961e-53	198.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42Z0A@68525|delta/epsilon subdivisions,2WUAC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_8700301_3	330214.NIDE2765	1.379e-15	80.0	COG4235@1|root,COG4235@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	cycH	-	3.4.21.105	ko:K02200,ko:K04018,ko:K19225,ko:K20543,ko:K21007	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.55.3	-	-	TPR_16,TPR_19,TPR_2,TPR_8
LZS3_k127_8700301_0	880073.Calab_2811	3.697e-159	529.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2NPC4@2323|unclassified Bacteria	2|Bacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	iAF987.Gmet_3470	CBS,TrkA_C,Voltage_CLC
LZS3_k127_8700301_2	1125863.JAFN01000001_gene1790	7.694e-42	171.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS3_k127_8700301_1	1238182.C882_2738	2.946e-91	341.0	COG3961@1|root,COG3961@2|Bacteria,1MW2F@1224|Proteobacteria,2TRXT@28211|Alphaproteobacteria,2JRNM@204441|Rhodospirillales	204441|Rhodospirillales	GH	Belongs to the TPP enzyme family	-	-	4.1.1.1,4.1.1.74	ko:K01568,ko:K04103	ko00010,ko00380,ko01100,ko01110,ko01130,map00010,map00380,map01100,map01110,map01130	-	R00014,R00755,R01974	RC00027,RC00375,RC00506,RC02744	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_8700301_4	1121377.KB906404_gene2858	1.22e-09	63.0	COG3393@1|root,COG3393@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,FR47,GNAT_acetyltran
LZS3_k127_8709257_1	314230.DSM3645_26649	3.102e-17	95.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
LZS3_k127_8709257_0	1144275.COCOR_06170	2.656e-22	111.0	COG0737@1|root,COG0737@2|Bacteria,1NDBC@1224|Proteobacteria,42V2W@68525|delta/epsilon subdivisions,2WS9M@28221|Deltaproteobacteria,2YV8Z@29|Myxococcales	28221|Deltaproteobacteria	F	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
LZS3_k127_8709257_2	751945.Theos_1606	0.0001406	54.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
LZS3_k127_8712634_2	402881.Plav_2502	2.09e-07	64.0	2EGAZ@1|root,33A2U@2|Bacteria,1NMCB@1224|Proteobacteria,2UMCZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8712634_0	450851.PHZ_c3034	2.886e-133	434.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2U36X@28211|Alphaproteobacteria,2KI9G@204458|Caulobacterales	204458|Caulobacterales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
LZS3_k127_8712634_1	391625.PPSIR1_01914	1.069e-26	118.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,Pup_ligase
LZS3_k127_8714907_4	404589.Anae109_0934	0.0001147	45.0	COG1585@1|root,COG1585@2|Bacteria,1PJH9@1224|Proteobacteria,42WNG@68525|delta/epsilon subdivisions,2WRM8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
LZS3_k127_8714907_1	404589.Anae109_0935	2.031e-119	391.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WKYT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
LZS3_k127_8714907_3	1380390.JIAT01000012_gene3188	1.825e-13	83.0	COG2706@1|root,COG3291@1|root,COG2706@2|Bacteria,COG3291@2|Bacteria,2HRFM@201174|Actinobacteria,4CTEG@84995|Rubrobacteria	84995|Rubrobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,PKD
LZS3_k127_8714907_0	1121937.AUHJ01000001_gene365	1.124e-147	474.0	COG2141@1|root,COG2141@2|Bacteria,1R76K@1224|Proteobacteria	1224|Proteobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
LZS3_k127_8714907_2	1313172.YM304_23300	4.317e-55	203.0	COG0657@1|root,COG0657@2|Bacteria,2I8XP@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
LZS3_k127_8723982_0	713586.KB900536_gene1951	6.14e-98	346.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,1WVY0@135613|Chromatiales	135613|Chromatiales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS3_k127_8723982_1	326427.Cagg_2504	4.029e-36	141.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi,375JU@32061|Chloroflexia	32061|Chloroflexia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
LZS3_k127_8724768_0	589865.DaAHT2_0063	0.0	1120.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2MHW3@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS3_k127_8752437_1	349521.HCH_01321	2.122e-09	69.0	COG1075@1|root,COG1075@2|Bacteria,1N2AK@1224|Proteobacteria,1S99T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF915
LZS3_k127_8752437_0	1056820.KB900647_gene2971	2.435e-10	73.0	2EBVP@1|root,335V3@2|Bacteria,1N9Z5@1224|Proteobacteria,1SF91@1236|Gammaproteobacteria,2PQ63@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8759030_3	290397.Adeh_0078	2.726e-05	49.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8759030_0	1458275.AZ34_06480	4.931e-69	245.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VPM0@28216|Betaproteobacteria,4ACTH@80864|Comamonadaceae	28216|Betaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_8759030_1	1341646.CBMO010000083_gene205	6.198e-59	221.0	COG1028@1|root,COG1028@2|Bacteria,2I4ES@201174|Actinobacteria,2361T@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_8759030_2	555079.Toce_2076	2.364e-37	144.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia,42GT3@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_8760957_1	197221.22295422	4.519e-44	184.0	COG1489@1|root,COG1489@2|Bacteria,1G1PM@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
LZS3_k127_8760957_0	880072.Desac_0027	2.877e-75	278.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS3_k127_8760957_2	391625.PPSIR1_36482	7.327e-25	121.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	cobC	-	3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
LZS3_k127_8761990_2	52598.EE36_06018	6.046e-05	46.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,3ZVBK@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ywrD	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_8761990_0	518766.Rmar_0596	1.269e-109	372.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
LZS3_k127_8761990_1	1282876.BAOK01000001_gene1455	1.585e-16	80.0	2DNUQ@1|root,32Z94@2|Bacteria,1N0SS@1224|Proteobacteria,2UFSC@28211|Alphaproteobacteria,4BT1H@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
LZS3_k127_889740_0	290397.Adeh_1310	4.497e-140	457.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2YXGJ@29|Myxococcales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS3_k127_889740_1	502025.Hoch_4931	6.336e-40	158.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_908054_0	1191523.MROS_2438	1.963e-148	479.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	gcdH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_908054_1	1112209.AHVZ01000032_gene2771	5.008e-134	455.0	COG2267@1|root,COG2267@2|Bacteria,1PARD@1224|Proteobacteria	1224|Proteobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_915198_3	1140.Synpcc7942_0638	1.126e-58	205.0	COG0346@1|root,COG0346@2|Bacteria,1G504@1117|Cyanobacteria,1H0G4@1129|Synechococcus	1117|Cyanobacteria	E	Lactoylglutathione lyase	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
LZS3_k127_915198_4	479434.Sthe_1363	5.462e-54	216.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi,27Y8N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
LZS3_k127_915198_2	1122223.KB890699_gene616	1.11e-91	309.0	COG0685@1|root,COG0685@2|Bacteria,1WI80@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	5,10-methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
LZS3_k127_915198_0	713586.KB900536_gene2290	4.85e-98	331.0	COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,1WZWK@135613|Chromatiales	135613|Chromatiales	G	pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS3_k127_915198_1	671143.DAMO_2569	4.831e-92	329.0	COG0530@1|root,COG0530@2|Bacteria,2NPSH@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS3_k127_915198_5	1380394.JADL01000016_gene399	3.595e-49	199.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2TU6K@28211|Alphaproteobacteria,2JQVK@204441|Rhodospirillales	204441|Rhodospirillales	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
LZS3_k127_918520_0	251221.35211202	1.243e-106	362.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
LZS3_k127_918520_1	656024.FsymDg_1573	8.722e-31	124.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_923171_7	10224.XP_002736701.1	0.0001025	46.0	COG1012@1|root,KOG2452@2759|Eukaryota,39MAJ@33154|Opisthokonta,3BCUT@33208|Metazoa,3CY12@33213|Bilateria	33208|Metazoa	F	belongs to the aldehyde dehydrogenase family	ALDH1L2	GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009109,GO:0009256,GO:0009258,GO:0009396,GO:0009397,GO:0009987,GO:0016053,GO:0016054,GO:0016155,GO:0016491,GO:0016620,GO:0016645,GO:0016646,GO:0016903,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019752,GO:0031974,GO:0032991,GO:0033721,GO:0034641,GO:0042219,GO:0042398,GO:0042558,GO:0042559,GO:0042560,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046394,GO:0046395,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046700,GO:0051186,GO:0051187,GO:0051188,GO:0055114,GO:0070013,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	1.5.1.6	ko:K00289	ko00670,map00670	-	R00941	RC00026	ko00000,ko00001,ko01000	-	-	-	Aldedh,Formyl_trans_C,Formyl_trans_N,PP-binding
LZS3_k127_923171_5	1121445.ATUZ01000014_gene1441	3.073e-18	94.0	COG0110@1|root,COG0110@2|Bacteria,1N6SQ@1224|Proteobacteria,42PE2@68525|delta/epsilon subdivisions,2WKVK@28221|Deltaproteobacteria,2MAU9@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
LZS3_k127_923171_4	644282.Deba_1242	1.624e-19	93.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42WGE@68525|delta/epsilon subdivisions,2WRF1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
LZS3_k127_923171_0	330214.NIDE3942	7.034e-132	435.0	COG2204@1|root,COG2204@2|Bacteria,3J10B@40117|Nitrospirae	40117|Nitrospirae	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_923171_2	671143.DAMO_1544	5.096e-46	185.0	COG4191@1|root,COG4191@2|Bacteria,2NPGF@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS3_k127_923171_3	448385.sce4091	6.92e-25	120.0	COG1366@1|root,COG1366@2|Bacteria,1MVPW@1224|Proteobacteria	1224|Proteobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	PAS_4,Protoglobin,STAS
LZS3_k127_923171_1	1125863.JAFN01000001_gene1039	2.042e-99	335.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
LZS3_k127_933267_1	148814.JI66_02925	2.465e-06	49.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,4HAKZ@91061|Bacilli,3F48D@33958|Lactobacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
LZS3_k127_933267_0	290397.Adeh_4214	1.564e-245	777.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2YUCV@29|Myxococcales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
LZS3_k127_944100_4	1205680.CAKO01000007_gene4314	1.908e-13	75.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2JPKU@204441|Rhodospirillales	204441|Rhodospirillales	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
LZS3_k127_944100_0	1304880.JAGB01000002_gene2026	2.193e-135	445.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
LZS3_k127_944100_1	1125863.JAFN01000001_gene2499	3.53e-134	438.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
LZS3_k127_944100_2	404589.Anae109_2280	1.427e-77	278.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,2YU88@29|Myxococcales	28221|Deltaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
LZS3_k127_944100_3	706587.Desti_0054	2.302e-21	106.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2MS60@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
LZS3_k127_945474_7	319795.Dgeo_1459	0.0007219	46.0	COG2323@1|root,COG2323@2|Bacteria,1WK27@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
LZS3_k127_945474_6	1254432.SCE1572_01740	0.0005579	50.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,43AJA@68525|delta/epsilon subdivisions,2X5ZM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_945474_5	1287276.X752_00150	1.006e-14	76.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2UGKQ@28211|Alphaproteobacteria,43M5D@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
LZS3_k127_945474_0	472759.Nhal_1977	3.931e-129	448.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T216@1236|Gammaproteobacteria,1X2RD@135613|Chromatiales	135613|Chromatiales	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS3_k127_945474_4	1095769.CAHF01000006_gene1856	1.513e-62	232.0	COG5637@1|root,COG5637@2|Bacteria,1RCEX@1224|Proteobacteria,2VQP4@28216|Betaproteobacteria,4771P@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
LZS3_k127_945474_1	649638.Trad_1839	1.146e-116	415.0	2CC7E@1|root,2Z7WG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_945474_3	1210884.HG799465_gene11494	1.738e-72	269.0	COG0329@1|root,COG0329@2|Bacteria,2IXAY@203682|Planctomycetes	203682|Planctomycetes	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_945474_2	314230.DSM3645_05780	2.12e-104	348.0	COG1902@1|root,COG1902@2|Bacteria,2IXBM@203682|Planctomycetes	203682|Planctomycetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
LZS3_k127_953291_0	926566.Terro_2657	3.622e-122	412.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
LZS3_k127_955222_1	1169152.AXVD01000009_gene30	6.82e-05	52.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4FW56@85025|Nocardiaceae	201174|Actinobacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
LZS3_k127_955222_0	941449.dsx2_1642	1.195e-135	453.0	COG4178@1|root,COG4178@2|Bacteria,1MW09@1224|Proteobacteria,43D2A@68525|delta/epsilon subdivisions,2WJNX@28221|Deltaproteobacteria,2MA4Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM ABC transporter	-	-	-	ko:K02471	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.203.11,3.A.1.203.4	-	-	ABC_membrane_2,ABC_tran
LZS3_k127_9590_1	1229780.BN381_400016	4.625e-41	173.0	COG1960@1|root,COG1960@2|Bacteria,2GITF@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_9590_0	1229780.BN381_400017	5.182e-177	568.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_9590_2	247633.GP2143_01735	2.452e-12	69.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,1S574@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
LZS3_k127_971426_0	1123267.JONN01000001_gene2208	5.263e-26	118.0	COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,2K0QK@204457|Sphingomonadales	204457|Sphingomonadales	S	to the N-terminal domain of Lon protease	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
LZS3_k127_971426_1	1384054.N790_12365	5.713e-06	58.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1X424@135614|Xanthomonadales	135614|Xanthomonadales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS3_k127_972559_1	1333998.M2A_2586	1.78e-35	156.0	COG0625@1|root,COG0625@2|Bacteria,1R696@1224|Proteobacteria,2U201@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
LZS3_k127_972559_0	1300345.LF41_281	8.348e-109	362.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RRHA@1236|Gammaproteobacteria,1XAP3@135614|Xanthomonadales	135614|Xanthomonadales	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
LZS3_k127_974543_2	1382359.JIAL01000001_gene1245	5.874e-20	96.0	COG0357@1|root,COG0357@2|Bacteria,3Y4W7@57723|Acidobacteria,2JJG7@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
LZS3_k127_974543_0	243231.GSU0106	5.208e-92	315.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,43T9A@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS3_k127_974543_1	555079.Toce_2275	5.444e-66	236.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,42FPF@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
LZS3_k127_974543_3	292459.STH3326	5.88e-10	71.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia	186801|Clostridia	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS3_k127_974543_4	1125863.JAFN01000001_gene2676	0.0002961	52.0	COG0711@1|root,COG0711@2|Bacteria,1NA9K@1224|Proteobacteria,42VN2@68525|delta/epsilon subdivisions,2WR8C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpX	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
## 2703 queries scanned
## Total time (seconds): 72.38426113128662
## Rate: 37.34 q/s