## Tue Feb 17 19:11:34 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/LZS3_bin.77.fa -m mmseqs --output LZS3_bin.77 --output_dir /data/result/bins/wyx/eggqs50+/LZS3_bin.77 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
LZS3_k127_1011661_11	96561.Dole_3155	1.767e-18	86.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MI9P@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
LZS3_k127_1011661_6	364733.XP_007799964.1	4.016e-47	190.0	COG0666@1|root,KOG0504@2759|Eukaryota,39YNX@33154|Opisthokonta,3Q6DZ@4751|Fungi,3RPDM@4890|Ascomycota	4751|Fungi	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
LZS3_k127_1011661_10	880072.Desac_2175	8.25e-22	101.0	2EM1D@1|root,33EQX@2|Bacteria,1R81Q@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1011661_12	880072.Desac_2175	1.616e-17	95.0	2EM1D@1|root,33EQX@2|Bacteria,1R81Q@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1011661_3	234267.Acid_2874	4.787e-116	384.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
LZS3_k127_1011661_2	1267535.KB906767_gene829	8.59e-143	478.0	COG0457@1|root,COG0457@2|Bacteria,3Y35N@57723|Acidobacteria,2JHIM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
LZS3_k127_1011661_5	1267535.KB906767_gene427	1.017e-68	239.0	2F161@1|root,33U75@2|Bacteria,3Y7M8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1011661_8	525897.Dbac_1018	7.227e-36	146.0	COG0388@1|root,COG0388@2|Bacteria,1NMSE@1224|Proteobacteria	1224|Proteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
LZS3_k127_1011661_7	234267.Acid_0652	2.585e-37	143.0	COG1695@1|root,COG1695@2|Bacteria,3Y5K9@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
LZS3_k127_1011661_4	1267535.KB906767_gene3339	3.535e-99	332.0	COG3279@1|root,COG3279@2|Bacteria,3Y3HR@57723|Acidobacteria,2JIXA@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component transcriptional regulator, LytTR family	-	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
LZS3_k127_1011661_1	402881.Plav_1121	2.023e-143	467.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS3_k127_1011661_0	926550.CLDAP_04390	2.781e-214	681.0	COG0114@1|root,COG0114@2|Bacteria,2GBNI@200795|Chloroflexi	200795|Chloroflexi	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS3_k127_1011661_15	582744.Msip34_1538	1.699e-06	55.0	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,2VY3B@28216|Betaproteobacteria,2KNXC@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1011661_14	675814.VIC_001392	6.332e-08	62.0	2AXAA@1|root,31P9D@2|Bacteria,1QKZJ@1224|Proteobacteria,1TJ61@1236|Gammaproteobacteria,1Y0NB@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1011661_16	402626.Rpic_2742	1.219e-05	52.0	2DGA3@1|root,32U6X@2|Bacteria,1N1ID@1224|Proteobacteria,2W2GF@28216|Betaproteobacteria,1K8MJ@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1011661_9	85643.Tmz1t_1390	1.736e-34	153.0	COG5652@1|root,COG5652@2|Bacteria,1R7IX@1224|Proteobacteria,2WEH7@28216|Betaproteobacteria,2KY9X@206389|Rhodocyclales	206389|Rhodocyclales	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III,VanZ
LZS3_k127_104528_0	1156844.KB891812_gene5070	3.741e-109	371.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,2GPPN@201174|Actinobacteria	201174|Actinobacteria	P	Chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
LZS3_k127_104528_3	314254.OA2633_14950	2.308e-11	76.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,43X8X@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	dop	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_104528_1	1122223.KB890696_gene471	7.848e-93	315.0	COG2421@1|root,COG2421@2|Bacteria	2|Bacteria	C	formamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
LZS3_k127_104528_2	404589.Anae109_0475	9.327e-55	199.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
LZS3_k127_1046732_5	867903.ThesuDRAFT_02222	3.365e-101	347.0	COG3378@1|root,COG5519@1|root,COG3378@2|Bacteria,COG5519@2|Bacteria,1TQP9@1239|Firmicutes,24AY6@186801|Clostridia	186801|Clostridia	L	Phage plasmid primase, P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5,PriCT_1,Prim-Pol
LZS3_k127_1046732_11	861299.J421_0021	6.735e-06	53.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
LZS3_k127_1046732_3	1267535.KB906767_gene2309	4.936e-110	363.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	kdgD	-	4.2.1.41	ko:K01707	ko00053,ko01100,map00053,map01100	-	R02279	RC00678	ko00000,ko00001,ko01000	-	-	-	DHDPS
LZS3_k127_1046732_6	1205680.CAKO01000027_gene4720	1.872e-69	246.0	COG5285@1|root,COG5285@2|Bacteria,1R7DG@1224|Proteobacteria,2TTB2@28211|Alphaproteobacteria,2JVYR@204441|Rhodospirillales	204441|Rhodospirillales	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS3_k127_1046732_1	1449063.JMLS01000013_gene6102	2.706e-134	442.0	COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,26R87@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_1046732_2	1267535.KB906767_gene3525	1.478e-119	407.0	COG1940@1|root,COG1940@2|Bacteria,3Y3B2@57723|Acidobacteria,2JIYY@204432|Acidobacteriia	204432|Acidobacteriia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS3_k127_1046732_8	234267.Acid_1025	8.214e-23	111.0	COG0738@1|root,COG0738@2|Bacteria,3Y6YP@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_1046732_7	1255043.TVNIR_3688	2.568e-30	123.0	COG3874@1|root,COG3874@2|Bacteria,1N4RT@1224|Proteobacteria,1SQI8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
LZS3_k127_1046732_9	338969.Rfer_0174	9.136e-22	102.0	2E21G@1|root,32X98@2|Bacteria,1N21H@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2953)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
LZS3_k127_1046732_4	1408473.JHXO01000009_gene3488	5.504e-103	353.0	COG0667@1|root,COG0667@2|Bacteria,4P42C@976|Bacteroidetes	976|Bacteroidetes	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_1110796_3	234267.Acid_7445	9.355e-49	181.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria	57723|Acidobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_1110796_1	234267.Acid_7350	1.22e-140	455.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria	57723|Acidobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS3_k127_1110796_0	1267535.KB906767_gene2936	3.247e-161	522.0	COG1351@1|root,COG1351@2|Bacteria,3Y3AY@57723|Acidobacteria,2JHXW@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
LZS3_k127_1110796_2	1123507.ATVQ01000001_gene1317	4.086e-137	451.0	COG0174@1|root,COG0174@2|Bacteria,2GK8A@201174|Actinobacteria,1W8DP@1268|Micrococcaceae	201174|Actinobacteria	E	Glutamine synthetase, catalytic domain	glnT	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
LZS3_k127_1112426_16	1267534.KB906754_gene3647	1.773e-12	76.0	COG2318@1|root,COG2318@2|Bacteria,3Y7GV@57723|Acidobacteria,2JMUY@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS3_k127_1112426_7	1267535.KB906767_gene4068	3.491e-54	199.0	COG1018@1|root,COG1018@2|Bacteria,3Y4SB@57723|Acidobacteria,2JJAW@204432|Acidobacteriia	204432|Acidobacteriia	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
LZS3_k127_1112426_15	234267.Acid_7485	2.513e-27	116.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
LZS3_k127_1112426_2	234267.Acid_2598	1.31e-122	400.0	COG0331@1|root,COG0331@2|Bacteria,3Y2TE@57723|Acidobacteria	57723|Acidobacteria	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
LZS3_k127_1112426_4	1340493.JNIF01000004_gene817	6.865e-87	294.0	COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria	57723|Acidobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_1112426_11	671143.DAMO_1603	9.75e-38	147.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS3_k127_1112426_14	234267.Acid_1194	6.507e-31	126.0	COG4911@1|root,COG4911@2|Bacteria,3Y4VB@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
LZS3_k127_1112426_10	926566.Terro_4138	1.641e-38	150.0	COG3303@1|root,COG3303@2|Bacteria,3Y7PT@57723|Acidobacteria,2JMPS@204432|Acidobacteriia	204432|Acidobacteriia	P	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
LZS3_k127_1112426_13	671143.DAMO_1603	1.618e-32	134.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS3_k127_1112426_9	378806.STAUR_1093	1.924e-44	169.0	2DK2X@1|root,3089T@2|Bacteria,1RF89@1224|Proteobacteria,439W6@68525|delta/epsilon subdivisions,2X5AE@28221|Deltaproteobacteria,2Z0C0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1112426_8	1121035.AUCH01000005_gene10	6.611e-47	182.0	2DBRJ@1|root,2ZAMD@2|Bacteria,1R498@1224|Proteobacteria,2VMV1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
LZS3_k127_1112426_0	215803.DB30_6572	2.53e-147	499.0	COG2304@1|root,COG2304@2|Bacteria,1MX4C@1224|Proteobacteria,439DU@68525|delta/epsilon subdivisions,2X4NR@28221|Deltaproteobacteria,2YZBD@29|Myxococcales	28221|Deltaproteobacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
LZS3_k127_1112426_5	1187851.A33M_1873	7.238e-76	264.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,3FD0Q@34008|Rhodovulum	28211|Alphaproteobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
LZS3_k127_1112426_12	1128421.JAGA01000001_gene2145	1.474e-34	138.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_05735	-	-	-	-	-	-	-	-	-	-	-	HTH_34
LZS3_k127_1112426_6	1128421.JAGA01000001_gene2144	3.04e-62	220.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_1112426_1	1396418.BATQ01000025_gene5256	9.201e-130	433.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_1112426_3	1340493.JNIF01000003_gene4351	3.669e-113	390.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1126916_0	234267.Acid_7711	5.113e-137	443.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria	57723|Acidobacteria	T	PFAM PhoH family protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
LZS3_k127_1126916_2	1089544.KB912942_gene2511	3.262e-87	299.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS3_k127_1126916_1	886293.Sinac_5669	2.722e-98	328.0	COG1657@1|root,COG3653@1|root,COG1657@2|Bacteria,COG3653@2|Bacteria,2IXWQ@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS3_k127_1128724_6	1340493.JNIF01000003_gene2887	1.433e-13	79.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HH@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1128724_3	247490.KSU1_B0364	7.619e-57	221.0	COG4191@1|root,COG4191@2|Bacteria,2J2BM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_1128724_4	1123487.KB892866_gene1770	2.558e-50	194.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KUJN@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Hemerythrin,HisKA,PAS_4,PAS_9
LZS3_k127_1128724_5	1265503.KB905162_gene3708	1.719e-17	95.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,2Q6B3@267889|Colwelliaceae	1236|Gammaproteobacteria	T	Bacterial regulatory protein, Fis family	fleR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_1128724_2	234267.Acid_0669	1.631e-79	278.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
LZS3_k127_1128724_1	234267.Acid_0669	1.957e-82	287.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
LZS3_k127_1128724_0	1123248.KB893359_gene2156	1.272e-266	853.0	COG1413@1|root,COG2133@1|root,COG3474@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,4NGAU@976|Bacteroidetes,1IWXQ@117747|Sphingobacteriia	976|Bacteroidetes	CG	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS3_k127_1128724_8	1121396.KB893121_gene3060	0.000729	44.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,42Q95@68525|delta/epsilon subdivisions,2WKM2@28221|Deltaproteobacteria,2MIMV@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_5,Phage_integrase
LZS3_k127_1128724_7	1121287.AUMU01000013_gene434	2.042e-05	46.0	2ABY9@1|root,311FK@2|Bacteria,4PG8Z@976|Bacteroidetes,1IMWF@117743|Flavobacteriia,3ZT0Q@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_115467_3	596152.DesU5LDRAFT_3930	2.413e-13	72.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42VSP@68525|delta/epsilon subdivisions,2WRGT@28221|Deltaproteobacteria,2MCUX@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM regulatory protein ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
LZS3_k127_115467_1	1122223.KB890696_gene368	1.74e-42	157.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
LZS3_k127_115467_5	330214.NIDE3826	4.958e-07	55.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,3J0XX@40117|Nitrospirae	40117|Nitrospirae	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
LZS3_k127_115467_0	266117.Rxyl_1929	3.169e-265	839.0	COG1067@1|root,COG1067@2|Bacteria,2H2TE@201174|Actinobacteria	201174|Actinobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
LZS3_k127_115467_6	319225.Plut_0297	5.687e-06	57.0	COG0589@1|root,COG0589@2|Bacteria,1FF41@1090|Chlorobi	1090|Chlorobi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_115467_2	478741.JAFS01000001_gene1448	9.167e-21	95.0	28P28@1|root,2ZBYC@2|Bacteria,46V4V@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_118804_8	28072.Nos7524_5414	0.0005876	47.0	COG1216@1|root,COG1216@2|Bacteria,1G3T8@1117|Cyanobacteria,1HNFR@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
LZS3_k127_118804_5	880073.Calab_1746	6.754e-44	163.0	2CIU6@1|root,32S8H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_118804_0	1267535.KB906767_gene218	1.217e-153	508.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_118804_2	234267.Acid_3188	1.287e-108	359.0	COG0037@1|root,COG0037@2|Bacteria,3Y548@57723|Acidobacteria	57723|Acidobacteria	D	PP-loop family	-	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
LZS3_k127_118804_6	234267.Acid_3187	1.629e-42	163.0	COG1392@1|root,COG1392@2|Bacteria,3Y58U@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
LZS3_k127_118804_1	234267.Acid_3186	1.104e-121	401.0	COG0306@1|root,COG0306@2|Bacteria,3Y3ZW@57723|Acidobacteria	57723|Acidobacteria	P	PFAM phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS3_k127_118804_7	314345.SPV1_09593	3.845e-31	130.0	2ETWY@1|root,32VZU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_118804_4	234267.Acid_7025	1.961e-48	184.0	2F5GG@1|root,33Y23@2|Bacteria,3Y7UU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_118804_3	234267.Acid_7859	2.106e-51	188.0	COG1565@1|root,COG1565@2|Bacteria,3Y583@57723|Acidobacteria	57723|Acidobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
LZS3_k127_1206847_0	1118054.CAGW01000082_gene3042	1.299e-152	502.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,4HC37@91061|Bacilli,26TMF@186822|Paenibacillaceae	91061|Bacilli	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
LZS3_k127_1206847_3	909663.KI867150_gene1927	2.3e-05	57.0	COG2304@1|root,COG4655@1|root,COG2304@2|Bacteria,COG4655@2|Bacteria,1QRPU@1224|Proteobacteria,4377D@68525|delta/epsilon subdivisions,2X288@28221|Deltaproteobacteria,2MR1Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad,VWA
LZS3_k127_1206847_2	1219072.VHA01S_023_00190	5.631e-06	55.0	COG4961@1|root,COG4961@2|Bacteria,1NMP4@1224|Proteobacteria,1SHEM@1236|Gammaproteobacteria,1XX8N@135623|Vibrionales	135623|Vibrionales	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS3_k127_1221606_0	639030.JHVA01000001_gene3222	2.305e-174	561.0	COG4993@1|root,COG4993@2|Bacteria,3Y6BH@57723|Acidobacteria	57723|Acidobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
LZS3_k127_1221606_1	518766.Rmar_1790	2.713e-117	392.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes	976|Bacteroidetes	Q	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS3_k127_1221606_2	1108045.GORHZ_066_00020	2.126e-12	73.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1248651_19	1267535.KB906767_gene5183	1.707e-18	87.0	COG0802@1|root,COG0802@2|Bacteria,3Y4WF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0079, ATPase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
LZS3_k127_1248651_3	234267.Acid_2158	1.565e-147	484.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,3Y3XN@57723|Acidobacteria	57723|Acidobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
LZS3_k127_1248651_11	861299.J421_5600	1.678e-92	316.0	COG1172@1|root,COG1172@2|Bacteria,1ZUX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10553	ko02010,map02010	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	BPD_transp_2
LZS3_k127_1248651_7	521674.Plim_1852	1.592e-107	356.0	COG0614@1|root,COG0614@2|Bacteria,2IXWX@203682|Planctomycetes	203682|Planctomycetes	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
LZS3_k127_1248651_9	234267.Acid_6406	1.452e-101	338.0	COG4974@1|root,COG4974@2|Bacteria,3Y3D0@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS3_k127_1248651_16	234267.Acid_6405	4.357e-45	171.0	2C62N@1|root,32TCB@2|Bacteria,3Y55K@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1248651_10	234267.Acid_5763	4.544e-96	322.0	COG0247@1|root,COG0247@2|Bacteria,3Y4IR@57723|Acidobacteria	57723|Acidobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
LZS3_k127_1248651_1	234267.Acid_5762	2.623e-177	570.0	COG1139@1|root,COG1139@2|Bacteria,3Y3R8@57723|Acidobacteria	57723|Acidobacteria	C	cluster binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
LZS3_k127_1248651_14	234267.Acid_5761	4.19e-56	203.0	COG1556@1|root,COG1556@2|Bacteria,3Y5T6@57723|Acidobacteria	57723|Acidobacteria	S	Pfam:DUF162	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
LZS3_k127_1248651_0	1340493.JNIF01000004_gene177	2.245e-186	619.0	COG1657@1|root,COG3391@1|root,COG1657@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K14647,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	-	-	-
LZS3_k127_1248651_17	1340493.JNIF01000003_gene1957	1.062e-34	138.0	2DB97@1|root,32TX2@2|Bacteria,3Y59S@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1248651_18	234267.Acid_7046	3.845e-32	127.0	2FF7H@1|root,3475G@2|Bacteria,3Y8K8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1248651_5	483219.LILAB_27285	3.656e-128	421.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
LZS3_k127_1248651_8	204669.Acid345_1955	2.716e-103	346.0	COG3253@1|root,COG3253@2|Bacteria,3Y39D@57723|Acidobacteria,2JK6X@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Chlorite dismutase	-	-	-	-	-	-	-	-	-	-	-	-	Chlor_dismutase
LZS3_k127_1248651_20	1502851.FG93_02086	6.021e-15	82.0	COG4319@1|root,COG4319@2|Bacteria,1RII1@1224|Proteobacteria,2UDKT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
LZS3_k127_1248651_13	234267.Acid_0123	1.317e-81	279.0	COG2096@1|root,COG2096@2|Bacteria,3Y77H@57723|Acidobacteria	57723|Acidobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
LZS3_k127_1248651_4	234267.Acid_6722	1.554e-131	428.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS3_k127_1248651_12	234267.Acid_6723	1.957e-87	293.0	COG0299@1|root,COG0299@2|Bacteria,3Y49G@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
LZS3_k127_1248651_2	234267.Acid_6707	2.602e-175	558.0	COG0162@1|root,COG0162@2|Bacteria,3Y2NC@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
LZS3_k127_1248651_6	243090.RB3767	6.1e-125	411.0	COG0473@1|root,COG0473@2|Bacteria,2IXJZ@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS3_k127_1248651_15	330084.JNYZ01000066_gene4988	9.816e-54	199.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_1249286_0	234267.Acid_1744	1.459e-267	863.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941,ko:K06350	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D,SLH
LZS3_k127_1249286_8	1267535.KB906767_gene2129	3.561e-41	165.0	COG0457@1|root,COG0457@2|Bacteria,3Y4MA@57723|Acidobacteria,2JJBW@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
LZS3_k127_1249286_3	1382359.JIAL01000001_gene1301	1.493e-175	570.0	COG0457@1|root,COG0457@2|Bacteria,3Y3VT@57723|Acidobacteria,2JHXZ@204432|Acidobacteriia	204432|Acidobacteriia	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
LZS3_k127_1249286_1	452637.Oter_2327	2.932e-198	644.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2327|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1249286_5	234267.Acid_6483	3.225e-127	426.0	COG1538@1|root,COG1538@2|Bacteria,3Y7Q2@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_1249286_2	234267.Acid_6484	1.488e-187	597.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	macB_1	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_1249286_6	234267.Acid_6485	1.296e-125	424.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	lprD	-	-	ko:K02005,ko:K02022	-	-	-	-	ko00000	-	-	-	HlyD_3
LZS3_k127_1249286_7	234267.Acid_6486	1.16e-123	409.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
LZS3_k127_1249286_4	1340493.JNIF01000003_gene4723	9.886e-157	520.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1,3.1.6.8	ko:K01130,ko:K01134	ko00140,ko00600,ko04142,map00140,map00600,map04142	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4976,Sulfatase
LZS3_k127_1272425_1	589865.DaAHT2_1228	8.154e-41	157.0	28P28@1|root,2ZBYC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1272425_0	1385935.N836_20045	0.0	1044.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1H7PF@1150|Oscillatoriales	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
LZS3_k127_1298609_8	1340493.JNIF01000003_gene3901	0.000946	44.0	COG0111@1|root,COG0111@2|Bacteria,3Y3VD@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_1298609_6	1207063.P24_04230	0.0004837	51.0	COG2161@1|root,COG2161@2|Bacteria,1R2Q0@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
LZS3_k127_1298609_5	1454004.AW11_03844	1.459e-08	64.0	COG1483@1|root,COG1483@2|Bacteria,1MX1G@1224|Proteobacteria,2VHB3@28216|Betaproteobacteria,1KQ8Z@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF499)	-	-	-	ko:K06922	-	-	-	-	ko00000	-	-	-	DUF499
LZS3_k127_1298609_1	1340493.JNIF01000003_gene3439	2.599e-155	503.0	COG4948@1|root,COG4948@2|Bacteria,3Y403@57723|Acidobacteria	2|Bacteria	M	mandelate racemase muconate lactonizing	-	GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_1298609_4	1340493.JNIF01000003_gene3896	1.164e-44	165.0	COG1703@1|root,COG1703@2|Bacteria,3Y40X@57723|Acidobacteria	57723|Acidobacteria	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,Glyoxalase_4
LZS3_k127_1298609_2	204669.Acid345_2365	2.555e-93	317.0	COG1703@1|root,COG1703@2|Bacteria,3Y40X@57723|Acidobacteria,2JHW8@204432|Acidobacteriia	204432|Acidobacteriia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
LZS3_k127_1298609_0	1267535.KB906767_gene5472	3.21e-184	582.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_1298609_3	502025.Hoch_5119	2.863e-62	220.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales	28221|Deltaproteobacteria	C	Sulfite reductase	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
LZS3_k127_1301735_17	228410.NE0622	7.265e-23	103.0	COG0662@1|root,COG0662@2|Bacteria,1RFTK@1224|Proteobacteria,2WG1F@28216|Betaproteobacteria,374QB@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_1301735_4	886293.Sinac_5956	2.155e-135	438.0	COG1052@1|root,COG1052@2|Bacteria,2IXCE@203682|Planctomycetes	203682|Planctomycetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.26,1.1.1.29	ko:K00015,ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_1301735_23	518766.Rmar_1232	0.0005146	47.0	COG3676@1|root,COG3677@1|root,COG3676@2|Bacteria,COG3677@2|Bacteria,4NS7V@976|Bacteroidetes	976|Bacteroidetes	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
LZS3_k127_1301735_22	661478.OP10G_2396	0.0004566	43.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
LZS3_k127_1301735_3	234267.Acid_3122	2.417e-145	486.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	2|Bacteria	G	PQQ-like domain	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
LZS3_k127_1301735_0	926549.KI421517_gene1092	1.921e-274	857.0	COG3420@1|root,COG3420@2|Bacteria,4P1XP@976|Bacteroidetes,47UIA@768503|Cytophagia	976|Bacteroidetes	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1301735_5	378806.STAUR_0034	1.03e-127	418.0	COG2267@1|root,COG2267@2|Bacteria,1MZG8@1224|Proteobacteria,42P0T@68525|delta/epsilon subdivisions,2WJ45@28221|Deltaproteobacteria,2YU6Y@29|Myxococcales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
LZS3_k127_1301735_9	1007103.AFHW01000025_gene338	7.527e-80	274.0	COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,26Y28@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
LZS3_k127_1301735_8	237368.SCABRO_02413	3.572e-82	286.0	29MQ2@1|root,308MT@2|Bacteria,2J179@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1301735_1	338963.Pcar_2933	1.471e-234	740.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,43S1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
LZS3_k127_1301735_16	234267.Acid_7304	3.454e-25	106.0	COG1828@1|root,COG1828@2|Bacteria,3Y5NE@57723|Acidobacteria	57723|Acidobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
LZS3_k127_1301735_2	234267.Acid_1088	4.272e-165	533.0	COG0486@1|root,COG0486@2|Bacteria,3Y3QJ@57723|Acidobacteria	57723|Acidobacteria	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
LZS3_k127_1301735_11	1267535.KB906767_gene3478	4.402e-46	171.0	COG1847@1|root,COG1847@2|Bacteria,3Y52C@57723|Acidobacteria,2JJF9@204432|Acidobacteriia	204432|Acidobacteriia	S	R3H domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	R3H
LZS3_k127_1301735_6	1340493.JNIF01000003_gene3082	9.295e-126	423.0	COG0706@1|root,COG0706@2|Bacteria,3Y3TD@57723|Acidobacteria	57723|Acidobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
LZS3_k127_1301735_18	545695.TREAZ_2141	2.441e-22	101.0	COG0759@1|root,COG0759@2|Bacteria,2J8TC@203691|Spirochaetes	203691|Spirochaetes	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
LZS3_k127_1301735_21	639030.JHVA01000001_gene2466	1.661e-14	79.0	COG0594@1|root,COG0594@2|Bacteria,3Y5EK@57723|Acidobacteria,2JJTR@204432|Acidobacteriia	204432|Acidobacteriia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
LZS3_k127_1301735_20	684949.ATTJ01000001_gene1893	3.525e-15	77.0	COG0230@1|root,COG0230@2|Bacteria,1WKP1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
LZS3_k127_1301735_19	234267.Acid_2006	3.207e-21	100.0	2DWVU@1|root,3424P@2|Bacteria,3Y8CU@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1301735_14	234267.Acid_5662	9.38e-29	121.0	COG1576@1|root,COG1576@2|Bacteria,3Y54B@57723|Acidobacteria	57723|Acidobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
LZS3_k127_1301735_13	1267535.KB906767_gene3549	4.428e-29	128.0	COG0799@1|root,COG0799@2|Bacteria,3Y5SD@57723|Acidobacteria	57723|Acidobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
LZS3_k127_1301735_7	1267535.KB906767_gene4930	7.15e-123	406.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS3_k127_1301735_15	1340493.JNIF01000004_gene260	9.476e-28	119.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	MA20_44825	-	-	-	-	-	-	-	-	-	-	-	DUF4440
LZS3_k127_1301735_10	234267.Acid_7906	2.864e-50	183.0	COG0629@1|root,COG0629@2|Bacteria,3Y4D2@57723|Acidobacteria	57723|Acidobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS3_k127_1316277_13	42099.EPrPV00000015083	1.083e-05	59.0	2D0Y8@1|root,2SG03@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_72
LZS3_k127_1316277_11	234267.Acid_4029	4.359e-14	87.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	ppe2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K22390	-	-	-	-	ko00000	-	-	-	Metallophos,Pur_ac_phosph_N,TAT_signal
LZS3_k127_1316277_8	234267.Acid_0414	8.498e-47	172.0	COG0756@1|root,COG0756@2|Bacteria,3Y58S@57723|Acidobacteria	57723|Acidobacteria	F	dUTPase	-	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
LZS3_k127_1316277_5	518766.Rmar_1570	7.417e-51	192.0	COG0345@1|root,COG0345@2|Bacteria,4NE6F@976|Bacteroidetes,1FIZF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
LZS3_k127_1316277_6	1173027.Mic7113_5573	3.996e-48	190.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
LZS3_k127_1316277_3	234267.Acid_1946	1.098e-75	267.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_1946|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1316277_0	1267535.KB906767_gene223	3.707e-311	989.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_1316277_1	1340493.JNIF01000003_gene3829	2.428e-264	853.0	COG1629@1|root,COG1629@2|Bacteria,3Y6CT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_1316277_4	406817.XNC1_4334	2.325e-52	193.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1RP9U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
LZS3_k127_1316277_7	870187.Thini_1087	1.916e-47	186.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVS@1236|Gammaproteobacteria,4634K@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
LZS3_k127_1316277_2	234267.Acid_5241	1.509e-91	308.0	COG1262@1|root,COG1262@2|Bacteria	234267.Acid_5241|-	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1316277_12	1047013.AQSP01000076_gene1470	4.761e-07	55.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_1316277_9	1047013.AQSP01000076_gene1470	5.881e-46	176.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_1316277_10	622637.KE124774_gene1497	1.057e-42	163.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2183 Transcriptional accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_1324128_9	1267535.KB906767_gene1063	5.305e-148	479.0	COG3684@1|root,COG3684@2|Bacteria,3Y33H@57723|Acidobacteria,2JIH2@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
LZS3_k127_1324128_15	234267.Acid_1839	5.859e-87	299.0	COG0196@1|root,COG0196@2|Bacteria,3Y34N@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
LZS3_k127_1324128_12	234267.Acid_1840	8.291e-101	336.0	COG1235@1|root,COG1235@2|Bacteria,3Y40S@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
LZS3_k127_1324128_23	234267.Acid_1841	2.609e-18	93.0	29CGV@1|root,2ZZF9@2|Bacteria,3Y4JX@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
LZS3_k127_1324128_16	234267.Acid_1543	6.193e-80	290.0	2EM41@1|root,33ETI@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
LZS3_k127_1324128_14	1267535.KB906767_gene1304	5.961e-88	299.0	COG1131@1|root,COG1131@2|Bacteria,3Y394@57723|Acidobacteria,2JINE@204432|Acidobacteriia	204432|Acidobacteriia	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_1324128_10	1267535.KB906767_gene399	4.999e-137	444.0	COG0533@1|root,COG0533@2|Bacteria,3Y2PN@57723|Acidobacteria,2JHJ0@204432|Acidobacteriia	204432|Acidobacteriia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
LZS3_k127_1324128_8	1267535.KB906767_gene477	4.935e-152	494.0	COG3119@1|root,COG3119@2|Bacteria,3Y3PF@57723|Acidobacteria,2JIZB@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_1324128_4	1267533.KB906738_gene2186	4.261e-237	755.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
LZS3_k127_1324128_17	234267.Acid_7218	1.073e-52	192.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
LZS3_k127_1324128_21	234267.Acid_0607	1.452e-32	131.0	COG3824@1|root,COG3824@2|Bacteria,3Y8W9@57723|Acidobacteria	57723|Acidobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
LZS3_k127_1324128_7	1340493.JNIF01000003_gene4759	3.451e-174	554.0	COG2355@1|root,COG2355@2|Bacteria,3Y3RS@57723|Acidobacteria	57723|Acidobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
LZS3_k127_1324128_11	639030.JHVA01000001_gene2021	4.139e-118	393.0	COG1858@1|root,COG1858@2|Bacteria,3Y46D@57723|Acidobacteria,2JJVZ@204432|Acidobacteriia	204432|Acidobacteriia	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS3_k127_1324128_20	909663.KI867151_gene3025	1.837e-34	142.0	COG4627@1|root,COG4627@2|Bacteria,1NKXY@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
LZS3_k127_1324128_18	751945.Theos_1306	1.1e-52	199.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase,UPF0020
LZS3_k127_1324128_19	1116472.MGMO_106c00080	1.308e-47	183.0	2EBDH@1|root,335E6@2|Bacteria,1NGH0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1324128_13	653733.Selin_2304	9.084e-90	308.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
LZS3_k127_1324128_3	234267.Acid_0830	8.111e-268	838.0	COG2936@1|root,COG2936@2|Bacteria,3Y2WR@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
LZS3_k127_1324128_6	1120973.AQXL01000113_gene753	7.503e-203	637.0	COG1960@1|root,COG1960@2|Bacteria,1UK89@1239|Firmicutes,4HAR5@91061|Bacilli,279JU@186823|Alicyclobacillaceae	91061|Bacilli	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_1324128_1	716928.AJQT01000079_gene991	1.087e-320	1007.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,4BI55@82115|Rhizobiaceae	28211|Alphaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C_2,Acyltransferase,PP-binding
LZS3_k127_1324128_2	234267.Acid_1744	2.221e-274	885.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941,ko:K06350	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D,SLH
LZS3_k127_1324128_0	1267535.KB906767_gene5042	0.0	1053.0	COG1629@1|root,COG1629@2|Bacteria,3Y2ZC@57723|Acidobacteria,2JK8R@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_1324128_5	1121472.AQWN01000011_gene1225	4.65e-227	712.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,26131@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh,Pro_dh
LZS3_k127_1335397_12	313603.FB2170_04530	1.363e-107	360.0	COG0385@1|root,COG0385@2|Bacteria,4NEIM@976|Bacteroidetes,1HY0F@117743|Flavobacteriia,2PGR5@252356|Maribacter	976|Bacteroidetes	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
LZS3_k127_1335397_24	234267.Acid_7407	9.962e-53	196.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,3Y4FC@57723|Acidobacteria	57723|Acidobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
LZS3_k127_1335397_17	204669.Acid345_3269	8.092e-93	315.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HZ@57723|Acidobacteria,2JI47@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_1335397_20	237368.SCABRO_03097	3.856e-78	279.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_16,TPR_8
LZS3_k127_1335397_16	234267.Acid_7409	5.81e-95	325.0	COG0438@1|root,COG0438@2|Bacteria,3Y68S@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_1335397_27	234267.Acid_7919	6.337e-46	177.0	COG2834@1|root,COG2834@2|Bacteria,3Y4A1@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
LZS3_k127_1335397_15	204669.Acid345_0559	6.158e-96	326.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,LolA_like,MacB_PCD
LZS3_k127_1335397_18	234267.Acid_7921	1.241e-87	294.0	COG1136@1|root,COG1136@2|Bacteria,3Y2QD@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_1335397_7	234267.Acid_1008	1.67e-178	574.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria	57723|Acidobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_1335397_10	1267535.KB906767_gene978	8.147e-159	519.0	COG0358@1|root,COG0358@2|Bacteria,3Y366@57723|Acidobacteria,2JIHT@204432|Acidobacteriia	204432|Acidobacteriia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
LZS3_k127_1335397_0	234267.Acid_5456	0.0	2318.0	COG0086@1|root,COG0086@2|Bacteria,3Y2FZ@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
LZS3_k127_1335397_1	234267.Acid_5457	0.0	2263.0	COG0085@1|root,COG0085@2|Bacteria,3Y36G@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
LZS3_k127_1335397_5	234267.Acid_6976	4.448e-211	679.0	28JZQ@1|root,2Z9PN@2|Bacteria,3Y4UW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1335397_33	1267535.KB906767_gene5066	1.752e-21	99.0	COG0784@1|root,COG0784@2|Bacteria,3Y8JB@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1335397_6	240015.ACP_2461	9.235e-193	611.0	COG0015@1|root,COG0015@2|Bacteria,3Y2QW@57723|Acidobacteria,2JIAC@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
LZS3_k127_1335397_19	234267.Acid_2439	2.036e-87	295.0	COG1235@1|root,COG1235@2|Bacteria,3Y3DW@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS3_k127_1335397_21	1340493.JNIF01000004_gene1042	7.964e-77	270.0	2DUZM@1|root,33T72@2|Bacteria,3Y7AK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1335397_30	472759.Nhal_1885	9.522e-30	123.0	COG0517@1|root,COG0517@2|Bacteria,1QTVM@1224|Proteobacteria,1SFWU@1236|Gammaproteobacteria,1X1W5@135613|Chromatiales	135613|Chromatiales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_1335397_3	266117.Rxyl_1929	1.799e-250	799.0	COG1067@1|root,COG1067@2|Bacteria,2H2TE@201174|Actinobacteria	201174|Actinobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
LZS3_k127_1335397_34	1121861.KB899911_gene1306	3.519e-08	64.0	2EVJY@1|root,33P02@2|Bacteria,1NMNA@1224|Proteobacteria,2UMPN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1335397_11	1396418.BATQ01000136_gene3721	3.022e-136	449.0	28P28@1|root,2ZBYC@2|Bacteria,46V4V@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1335397_31	478741.JAFS01000001_gene1447	2.169e-29	130.0	COG1082@1|root,COG1082@2|Bacteria,46VY2@74201|Verrucomicrobia,37GRU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	iolE	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_1335397_4	234267.Acid_0177	4.88e-248	776.0	COG0119@1|root,COG0119@2|Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
LZS3_k127_1335397_8	234267.Acid_0178	6.837e-163	519.0	COG0059@1|root,COG0059@2|Bacteria,3Y34M@57723|Acidobacteria	57723|Acidobacteria	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
LZS3_k127_1335397_25	234267.Acid_0179	8.625e-47	176.0	COG0440@1|root,COG0440@2|Bacteria,3Y580@57723|Acidobacteria	57723|Acidobacteria	E	Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
LZS3_k127_1335397_2	234267.Acid_0180	6.806e-253	792.0	COG0028@1|root,COG0028@2|Bacteria,3Y3GJ@57723|Acidobacteria	57723|Acidobacteria	EH	PFAM Thiamine pyrophosphate	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_1335397_28	234267.Acid_7429	1.099e-39	154.0	2F82T@1|root,340G8@2|Bacteria,3Y8B9@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1335397_29	1131269.AQVV01000028_gene41	5.938e-34	145.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
LZS3_k127_1335397_26	1089550.ATTH01000001_gene332	2.417e-46	183.0	COG0654@1|root,COG0654@2|Bacteria,4PM2V@976|Bacteroidetes,1FJWJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Pyr_redox_2
LZS3_k127_1335397_32	1394178.AWOO02000026_gene5192	1.663e-22	107.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Laminin_G_3
LZS3_k127_1335397_14	1340493.JNIF01000003_gene4381	7.81e-100	334.0	COG0546@1|root,COG0546@2|Bacteria,3Y621@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase
LZS3_k127_1335397_23	234267.Acid_4335	1.663e-54	199.0	COG0671@1|root,COG0671@2|Bacteria,3Y5XF@57723|Acidobacteria	57723|Acidobacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
LZS3_k127_1335397_13	661478.OP10G_1553	3.771e-105	359.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_1335397_9	670292.JH26_16730	2.335e-160	518.0	COG1541@1|root,COG1541@2|Bacteria,1R7WG@1224|Proteobacteria,2U4M0@28211|Alphaproteobacteria,1JWE6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
LZS3_k127_1335397_22	1121406.JAEX01000005_gene3125	7.425e-56	203.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2M8CP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS3_k127_1341140_10	234267.Acid_7890	3.908e-69	243.0	COG0134@1|root,COG0134@2|Bacteria,3Y3TH@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
LZS3_k127_1341140_12	1267535.KB906767_gene286	9.528e-48	178.0	COG0135@1|root,COG0135@2|Bacteria,3Y50K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
LZS3_k127_1341140_4	1267535.KB906767_gene285	4.255e-188	596.0	COG0133@1|root,COG0133@2|Bacteria,3Y45B@57723|Acidobacteria,2JIVM@204432|Acidobacteriia	204432|Acidobacteriia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_1341140_7	1267535.KB906767_gene284	1.235e-92	311.0	COG0159@1|root,COG0159@2|Bacteria,3Y3X2@57723|Acidobacteria,2JI7C@204432|Acidobacteriia	204432|Acidobacteriia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
LZS3_k127_1341140_14	234267.Acid_7886	2.989e-18	89.0	COG1605@1|root,COG1605@2|Bacteria,3Y53J@57723|Acidobacteria	57723|Acidobacteria	E	chorismate mutase	-	-	-	-	-	-	-	-	-	-	-	-	CM_2
LZS3_k127_1341140_9	234267.Acid_7884	6.532e-70	246.0	COG0287@1|root,COG0287@2|Bacteria,3Y4CK@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
LZS3_k127_1341140_15	1121904.ARBP01000002_gene7107	4.5e-17	91.0	COG0664@1|root,COG0664@2|Bacteria,4NKW5@976|Bacteroidetes,47N83@768503|Cytophagia	976|Bacteroidetes	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_1341140_3	234267.Acid_1490	5.362e-217	691.0	COG3276@1|root,COG3276@2|Bacteria,3Y6R2@57723|Acidobacteria	57723|Acidobacteria	J	Elongation factor SelB, winged helix	-	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
LZS3_k127_1341140_13	1033802.SSPSH_000734	7.688e-42	156.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,1S644@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2288,iAF1260.b2288,iAPECO1_1312.APECO1_4277,iB21_1397.B21_02173,iBWG_1329.BWG_2062,iE2348C_1286.E2348C_2428,iEC042_1314.EC042_2529,iEC55989_1330.EC55989_2532,iECABU_c1320.ECABU_c26200,iECBD_1354.ECBD_1373,iECB_1328.ECB_02213,iECDH10B_1368.ECDH10B_2450,iECDH1ME8569_1439.ECDH1ME8569_2225,iECD_1391.ECD_02213,iECED1_1282.ECED1_2752,iECH74115_1262.ECH74115_3427,iECIAI1_1343.ECIAI1_2362,iECIAI39_1322.ECIAI39_2435,iECO103_1326.ECO103_2752,iECO26_1355.ECO26_3276,iECOK1_1307.ECOK1_2521,iECP_1309.ECP_2327,iECS88_1305.ECS88_2435,iECSE_1348.ECSE_2545,iECSP_1301.ECSP_3162,iECUMN_1333.ECUMN_2627,iECW_1372.ECW_m2476,iECs_1301.ECs3172,iEKO11_1354.EKO11_1479,iETEC_1333.ETEC_2423,iEcDH1_1363.EcDH1_1369,iEcE24377_1341.EcE24377A_2581,iEcHS_1320.EcHS_A2437,iEcSMS35_1347.EcSMS35_2442,iEcolC_1368.EcolC_1364,iG2583_1286.G2583_2825,iJN746.PP_4119,iJO1366.b2288,iJR904.b2288,iLF82_1304.LF82_1539,iNRG857_1313.NRG857_11585,iSBO_1134.SBO_2321,iSDY_1059.SDY_2484,iSFV_1184.SFV_2355,iSF_1195.SF2364,iSFxv_1172.SFxv_2608,iSSON_1240.SSON_2345,iS_1188.S2499,iSbBS512_1146.SbBS512_E2664,iUMN146_1321.UM146_05375,iUTI89_1310.UTI89_C2568,iWFL_1372.ECW_m2476,iY75_1357.Y75_RS11995,ic_1306.c2829	Oxidored_q4
LZS3_k127_1341140_6	472759.Nhal_2141	4.4e-107	351.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
LZS3_k127_1341140_1	1267535.KB906767_gene57	1.254e-303	938.0	COG0649@1|root,COG0649@2|Bacteria,3Y3N1@57723|Acidobacteria,2JIDU@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
LZS3_k127_1341140_11	1123368.AUIS01000006_gene658	1.377e-66	233.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,2NCTW@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
LZS3_k127_1341140_2	1267535.KB906767_gene59	1.901e-222	698.0	COG1894@1|root,COG1894@2|Bacteria,3Y2NM@57723|Acidobacteria,2JI09@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
LZS3_k127_1341140_0	1266925.JHVX01000004_gene1249	0.0	1150.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,373XN@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
LZS3_k127_1341140_5	1267535.KB906767_gene61	5.201e-162	516.0	COG1005@1|root,COG1005@2|Bacteria,3Y3VS@57723|Acidobacteria,2JHQZ@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
LZS3_k127_1341140_8	1267535.KB906767_gene62	5.075e-91	300.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2281,iAF1260.b2281,iAPECO1_1312.APECO1_4284,iB21_1397.B21_02166,iBWG_1329.BWG_2055,iE2348C_1286.E2348C_2421,iEC042_1314.EC042_2522,iEC55989_1330.EC55989_2525,iECABU_c1320.ECABU_c26130,iECBD_1354.ECBD_1380,iECB_1328.ECB_02206,iECDH10B_1368.ECDH10B_2443,iECDH1ME8569_1439.ECDH1ME8569_2218,iECD_1391.ECD_02206,iECED1_1282.ECED1_2745,iECH74115_1262.ECH74115_3420,iECIAI1_1343.ECIAI1_2355,iECIAI39_1322.ECIAI39_2428,iECNA114_1301.ECNA114_2371,iECO103_1326.ECO103_2745,iECO111_1330.ECO111_3029,iECO26_1355.ECO26_3269,iECOK1_1307.ECOK1_2514,iECP_1309.ECP_2320,iECS88_1305.ECS88_2428,iECSE_1348.ECSE_2538,iECSF_1327.ECSF_2158,iECSP_1301.ECSP_3155,iECUMN_1333.ECUMN_2620,iECW_1372.ECW_m2469,iECs_1301.ECs3165,iEKO11_1354.EKO11_1486,iETEC_1333.ETEC_2416,iEcDH1_1363.EcDH1_1376,iEcE24377_1341.EcE24377A_2574,iEcHS_1320.EcHS_A2430,iEcSMS35_1347.EcSMS35_2435,iEcolC_1368.EcolC_1371,iG2583_1286.G2583_2818,iJO1366.b2281,iJR904.b2281,iLF82_1304.LF82_1546,iNRG857_1313.NRG857_11550,iPC815.YPO2548,iSBO_1134.SBO_2314,iSFV_1184.SFV_2348,iSF_1195.SF2357,iSFxv_1172.SFxv_2601,iS_1188.S2492,iSbBS512_1146.SbBS512_E2657,iUMN146_1321.UM146_05410,iUMNK88_1353.UMNK88_2831,iUTI89_1310.UTI89_C2561,iWFL_1372.ECW_m2469,iY75_1357.Y75_RS11960,iZ_1308.Z3540,ic_1306.c2822	Fer4
LZS3_k127_135755_6	240015.ACP_0450	7.914e-51	186.0	COG2801@1|root,COG2801@2|Bacteria,3Y6NP@57723|Acidobacteria,2JNG9@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_135755_0	234267.Acid_5892	4.321e-230	724.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
LZS3_k127_135755_2	234267.Acid_6421	1.656e-92	310.0	COG0500@1|root,COG2226@2|Bacteria,3Y8SA@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_135755_3	768671.ThimaDRAFT_0596	5.874e-73	261.0	COG3126@1|root,COG3187@1|root,COG3650@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,COG3650@2|Bacteria,1MXIV@1224|Proteobacteria,1T10X@1236|Gammaproteobacteria,1X2MW@135613|Chromatiales	135613|Chromatiales	O	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	-	-	-	-	-	-	-	-	-	META,YscW
LZS3_k127_135755_7	1121396.KB893061_gene2686	3.155e-14	86.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WKBS@28221|Deltaproteobacteria,2MIDZ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
LZS3_k127_135755_5	1267535.KB906767_gene34	1.291e-61	218.0	COG0632@1|root,COG0632@2|Bacteria,3Y4KI@57723|Acidobacteria,2JJCJ@204432|Acidobacteriia	204432|Acidobacteriia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
LZS3_k127_135755_1	234267.Acid_0957	3.484e-152	487.0	COG2255@1|root,COG2255@2|Bacteria,3Y2RP@57723|Acidobacteria	57723|Acidobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
LZS3_k127_135755_4	204669.Acid345_4748	2.63e-71	246.0	COG1428@1|root,COG1428@2|Bacteria,3Y759@57723|Acidobacteria,2JMB9@204432|Acidobacteriia	204432|Acidobacteriia	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
LZS3_k127_1358090_6	246197.MXAN_7200	1.988e-06	61.0	COG0708@1|root,COG0708@2|Bacteria,1QXVQ@1224|Proteobacteria,43C8I@68525|delta/epsilon subdivisions,2X7IX@28221|Deltaproteobacteria,2YTYF@29|Myxococcales	28221|Deltaproteobacteria	L	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,He_PIG,LTD
LZS3_k127_1358090_7	391596.PBAL39_25275	2.943e-05	57.0	COG0018@1|root,COG3210@1|root,COG3266@1|root,COG4409@1|root,COG0018@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG4409@2|Bacteria,4NQ80@976|Bacteroidetes	976|Bacteroidetes	G	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
LZS3_k127_1358090_3	234267.Acid_0274	2.374e-16	93.0	COG2911@1|root,COG2911@2|Bacteria,3Y8JR@57723|Acidobacteria	57723|Acidobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1358090_0	880070.Cycma_4444	2.751e-169	549.0	COG5476@1|root,COG5476@2|Bacteria,4NKYT@976|Bacteroidetes,47XQY@768503|Cytophagia	976|Bacteroidetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
LZS3_k127_1358090_4	1121405.dsmv_0101	1.508e-10	68.0	COG3216@1|root,COG3216@2|Bacteria,1QEG2@1224|Proteobacteria,42VUY@68525|delta/epsilon subdivisions,2WRD1@28221|Deltaproteobacteria,2MM28@213118|Desulfobacterales	28221|Deltaproteobacteria	S	protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
LZS3_k127_1358090_1	1267535.KB906767_gene2266	5.351e-45	175.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS3_k127_1358090_2	234267.Acid_0380	7.026e-27	116.0	COG1502@1|root,COG1502@2|Bacteria,3Y2GD@57723|Acidobacteria	57723|Acidobacteria	I	PLD-like domain	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS3_k127_1358090_5	204669.Acid345_0495	2.233e-10	61.0	COG1502@1|root,COG1502@2|Bacteria,3Y2GD@57723|Acidobacteria,2JKZ7@204432|Acidobacteriia	204432|Acidobacteriia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS3_k127_137223_5	234267.Acid_7682	7.331e-90	304.0	COG2133@1|root,COG2133@2|Bacteria,3Y6W0@57723|Acidobacteria	57723|Acidobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
LZS3_k127_137223_12	2325.TKV_c11310	2.483e-11	69.0	COG3071@1|root,COG3071@2|Bacteria,1UHZ2@1239|Firmicutes,25E7P@186801|Clostridia,42JFQ@68295|Thermoanaerobacterales	186801|Clostridia	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
LZS3_k127_137223_1	504472.Slin_4601	2.229e-218	682.0	COG1063@1|root,COG1063@2|Bacteria,4NIU2@976|Bacteroidetes,47MH0@768503|Cytophagia	976|Bacteroidetes	E	Alcohol dehydrogenase GroES-like domain	-	-	1.2.1.46	ko:K00148	ko00625,ko00680,ko01100,ko01120,ko01200,map00625,map00680,map01100,map01120,map01200	-	R00604	RC00188	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_137223_4	1210884.HG799475_gene15229	7.181e-122	407.0	COG3119@1|root,COG3119@2|Bacteria,2IYGF@203682|Planctomycetes	203682|Planctomycetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_137223_6	234267.Acid_5279	1.223e-67	238.0	COG0363@1|root,COG0363@2|Bacteria,3Y430@57723|Acidobacteria	57723|Acidobacteria	G	PFAM glucosamine galactosamine-6-phosphate isomerase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
LZS3_k127_137223_0	1340493.JNIF01000004_gene597	4.33e-232	755.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_137223_10	234267.Acid_1062	4.14e-37	144.0	COG2165@1|root,COG2165@2|Bacteria,3Y4ZX@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
LZS3_k127_137223_9	1267535.KB906767_gene847	1.688e-38	157.0	COG2165@1|root,COG2165@2|Bacteria,3Y4RJ@57723|Acidobacteria,2JJB4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
LZS3_k127_137223_2	234267.Acid_1060	9.421e-182	597.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,3Y2G2@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N,TPR_8
LZS3_k127_137223_8	234267.Acid_1059	1.343e-45	188.0	COG0691@1|root,COG0691@2|Bacteria,3Y4CC@57723|Acidobacteria	57723|Acidobacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
LZS3_k127_137223_13	1337936.IJ00_09775	0.0004827	44.0	COG0111@1|root,COG0111@2|Bacteria,1G5A9@1117|Cyanobacteria,1HJAY@1161|Nostocales	1117|Cyanobacteria	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_137223_3	1340493.JNIF01000003_gene2187	8.672e-123	411.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_137223_7	68570.DC74_7630	3.425e-62	226.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria	201174|Actinobacteria	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
LZS3_k127_137223_11	111780.Sta7437_4007	1.482e-12	68.0	COG2442@1|root,COG2442@2|Bacteria,1GA44@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
LZS3_k127_1388132_2	439235.Dalk_3479	2.656e-82	291.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,42MA2@68525|delta/epsilon subdivisions,2WKBM@28221|Deltaproteobacteria,2MHN3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
LZS3_k127_1388132_4	1469607.KK073768_gene1009	4.665e-20	104.0	COG3039@1|root,COG3039@2|Bacteria,1G3YX@1117|Cyanobacteria	1117|Cyanobacteria	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
LZS3_k127_1388132_1	234267.Acid_7937	6.764e-123	397.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_1388132_0	1340493.JNIF01000003_gene3066	8.171e-133	443.0	COG1566@1|root,COG1566@2|Bacteria,3Y9B7@57723|Acidobacteria	57723|Acidobacteria	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
LZS3_k127_1388132_3	234267.Acid_2225	9.067e-69	239.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	coxS	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
LZS3_k127_1395226_18	762903.Pedsa_0685	3.922e-48	183.0	COG2942@1|root,COG2942@2|Bacteria,4NEFV@976|Bacteroidetes	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
LZS3_k127_1395226_1	330214.NIDE3701	3.065e-160	512.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
LZS3_k127_1395226_17	330214.NIDE0159	1.433e-49	183.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	yurZ	-	2.3.1.12,4.1.1.44	ko:K00627,ko:K01607	ko00010,ko00020,ko00362,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00020,map00362,map00620,map01100,map01110,map01120,map01130,map01200,map01220	M00307	R00209,R02569,R03470	RC00004,RC00938,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CMD
LZS3_k127_1395226_12	234267.Acid_0316	2.284e-72	252.0	COG2094@1|root,COG2094@2|Bacteria,3Y5DM@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
LZS3_k127_1395226_16	1379698.RBG1_1C00001G0813	3.504e-53	208.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
LZS3_k127_1395226_4	234267.Acid_7344	9.383e-119	393.0	COG0337@1|root,COG0337@2|Bacteria,3Y2T4@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
LZS3_k127_1395226_13	234267.Acid_7345	4.017e-72	254.0	COG0500@1|root,COG2226@2|Bacteria,3Y44I@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
LZS3_k127_1395226_22	240015.ACP_3066	5.145e-16	88.0	29C91@1|root,33WJ9@2|Bacteria,3Y7U7@57723|Acidobacteria,2JN2M@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1395226_9	118168.MC7420_1134	1.229e-76	264.0	COG0317@1|root,COG0317@2|Bacteria,1G0F8@1117|Cyanobacteria,1HA1X@1150|Oscillatoriales	1117|Cyanobacteria	KT	PFAM Metal-dependent phosphohydrolase, HD	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
LZS3_k127_1395226_14	1267535.KB906767_gene3453	2.295e-64	241.0	COG0673@1|root,COG0673@2|Bacteria,3Y4RG@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_1395226_2	234267.Acid_1822	2.675e-142	467.0	COG0531@1|root,COG0531@2|Bacteria,3Y7AX@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS3_k127_1395226_8	616991.JPOO01000003_gene2353	3.404e-81	287.0	COG1921@1|root,COG1921@2|Bacteria,4NIIG@976|Bacteroidetes,1I090@117743|Flavobacteriia	976|Bacteroidetes	H	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
LZS3_k127_1395226_21	234267.Acid_0422	2.871e-22	105.0	292F3@1|root,2ZPZC@2|Bacteria,3Y90G@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1395226_20	234267.Acid_0470	1.525e-26	126.0	COG1361@1|root,COG3391@1|root,COG4625@1|root,COG1361@2|Bacteria,COG3391@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	57723|Acidobacteria	M	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
LZS3_k127_1395226_3	497964.CfE428DRAFT_5616	9.485e-120	402.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DLH,DUF1929,Glyoxal_oxid_N
LZS3_k127_1395226_11	402777.KB235903_gene1331	1.272e-72	250.0	COG0225@1|root,COG0225@2|Bacteria,1G4A7@1117|Cyanobacteria,1HEC0@1150|Oscillatoriales	1117|Cyanobacteria	O	Peptide methionine sulfoxide reductase	msrA2	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
LZS3_k127_1395226_5	1210884.HG799466_gene12576	1.996e-96	343.0	COG0222@1|root,COG0222@2|Bacteria,2J50P@203682|Planctomycetes	203682|Planctomycetes	J	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
LZS3_k127_1395226_23	1267535.KB906767_gene1061	6.547e-09	69.0	COG0457@1|root,COG0457@2|Bacteria,3Y4E6@57723|Acidobacteria,2JKG2@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2
LZS3_k127_1395226_25	1121439.dsat_1309	1.217e-05	53.0	COG2204@1|root,COG2204@2|Bacteria,1MVWX@1224|Proteobacteria,42MIB@68525|delta/epsilon subdivisions,2WJQK@28221|Deltaproteobacteria,2M8JJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Sigma54_activat
LZS3_k127_1395226_19	42256.RradSPS_2497	1.2e-33	138.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	ahyR	-	-	ko:K07782,ko:K15852	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	Autoind_bind,GerE
LZS3_k127_1395226_6	1408813.AYMG01000013_gene1271	2.934e-94	314.0	COG0684@1|root,COG0684@2|Bacteria,4NHRR@976|Bacteroidetes,1IWQG@117747|Sphingobacteriia	976|Bacteroidetes	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
LZS3_k127_1395226_7	1340493.JNIF01000003_gene1444	6.845e-94	318.0	COG1082@1|root,COG1082@2|Bacteria,3Y69B@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_1395226_24	716928.AJQT01000035_gene840	4.709e-08	66.0	COG0508@1|root,COG0790@1|root,COG1196@1|root,COG3409@1|root,COG0508@2|Bacteria,COG0790@2|Bacteria,COG1196@2|Bacteria,COG3409@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,4B8SF@82115|Rhizobiaceae	28211|Alphaproteobacteria	DM	FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	PG_binding_1,Sel1
LZS3_k127_1395226_0	1185876.BN8_04111	1.759e-166	539.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,47KNU@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS3_k127_1395226_15	1123023.JIAI01000005_gene727	1.57e-63	245.0	COG0823@1|root,COG0823@2|Bacteria,2ID3I@201174|Actinobacteria	201174|Actinobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1395226_10	234267.Acid_1067	2.022e-75	261.0	COG0329@1|root,COG0329@2|Bacteria,3Y30K@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.1.3.16	ko:K18123	ko00330,ko00630,ko01100,map00330,map00630,map01100	-	R00470,R00471	RC00307,RC00308	ko00000,ko00001,ko01000	-	-	-	DHDPS
LZS3_k127_1444756_4	485917.Phep_1497	8.986e-12	78.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_1444756_3	156889.Mmc1_2786	5.495e-13	71.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_1444756_0	1340493.JNIF01000003_gene3842	0.0	1064.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
LZS3_k127_1444756_1	1123242.JH636436_gene263	2.534e-218	689.0	COG3119@1|root,COG3119@2|Bacteria,2IX1H@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_1444756_2	706439.HMPREF9057_01292	3.502e-51	202.0	COG0515@1|root,COG0515@2|Bacteria,2IAIB@201174|Actinobacteria,4D749@85005|Actinomycetales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_1462745_1	240016.ABIZ01000001_gene4353	1.718e-198	635.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
LZS3_k127_1462745_3	861299.J421_0248	3.415e-162	557.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1ZUXK@142182|Gemmatimonadetes	2|Bacteria	T	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
LZS3_k127_1462745_5	1131269.AQVV01000013_gene1768	6.087e-66	233.0	COG0602@1|root,COG0602@2|Bacteria	2|Bacteria	H	queuosine metabolic process	queE	-	1.97.1.4,4.3.99.3	ko:K04068,ko:K10026	ko00790,ko01100,map00790,map01100	-	R04710,R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
LZS3_k127_1462745_4	1340493.JNIF01000003_gene1816	8.506e-110	369.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	He_PIG,NHL,SGL
LZS3_k127_1462745_6	1340493.JNIF01000003_gene3786	2.521e-59	209.0	COG0041@1|root,COG0041@2|Bacteria,3Y4MB@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
LZS3_k127_1462745_2	314345.SPV1_13042	5.344e-179	577.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria	1224|Proteobacteria	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
LZS3_k127_1462745_9	690850.Desaf_0178	3.928e-13	74.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,42RI1@68525|delta/epsilon subdivisions,2WNBG@28221|Deltaproteobacteria,2MB6T@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
LZS3_k127_1462745_11	80884.CCF32859	1.741e-06	60.0	COG3940@1|root,2SM7B@2759|Eukaryota,39B73@33154|Opisthokonta,3P051@4751|Fungi,3QRQM@4890|Ascomycota,216KX@147550|Sordariomycetes,1F19U@1028384|Glomerellales	4751|Fungi	G	Glycosyl hydrolase family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32N,Glyco_hydro_43,Laminin_G_3
LZS3_k127_1462745_7	670487.Ocepr_0476	8.81e-25	111.0	COG0789@1|root,COG0789@2|Bacteria,1WK2F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Transcription regulator MerR DNA binding	-	-	-	ko:K13638	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
LZS3_k127_1462745_0	1121423.JONT01000011_gene219	2.029e-230	747.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,2608V@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS3_k127_1462745_10	1340493.JNIF01000004_gene233	3.523e-10	60.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_1485641_14	749222.Nitsa_1722	1.22e-15	89.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
LZS3_k127_1485641_10	1313301.AUGC01000001_gene1578	4.148e-55	207.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes	976|Bacteroidetes	M	Pfam Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
LZS3_k127_1485641_11	563192.HMPREF0179_02400	1.643e-52	202.0	COG0438@1|root,COG0438@2|Bacteria,1P24Q@1224|Proteobacteria	1224|Proteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1485641_6	234267.Acid_2500	6.848e-115	381.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,3Y4I2@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
LZS3_k127_1485641_4	1229909.NSED_09945	3.282e-132	434.0	COG0451@1|root,arCOG04762@2157|Archaea	2157|Archaea	GM	PFAM NAD-dependent epimerase dehydratase	sqdB	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
LZS3_k127_1485641_1	1267535.KB906767_gene2208	1.008e-158	531.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,3Y2V7@57723|Acidobacteria,2JIYH@204432|Acidobacteriia	204432|Acidobacteriia	D	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR
LZS3_k127_1485641_12	1267535.KB906767_gene4540	1.415e-35	144.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601,ko:K05785	-	-	-	-	ko00000,ko03000,ko03009,ko03021	-	-	-	KOW,NusG
LZS3_k127_1485641_2	756272.Plabr_3240	1.124e-153	498.0	COG3119@1|root,COG3386@1|root,COG3119@2|Bacteria,COG3386@2|Bacteria,2J1T1@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_1485641_3	234267.Acid_3254	3.451e-137	445.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_1485641_5	234267.Acid_3716	3.334e-127	417.0	COG0520@1|root,COG0520@2|Bacteria,3Y632@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS3_k127_1485641_0	323848.Nmul_A1969	9.73e-198	631.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2VKEE@28216|Betaproteobacteria,372CG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
LZS3_k127_1485641_7	234267.Acid_4555	1.367e-81	293.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_4555|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1485641_13	517418.Ctha_1380	9.873e-25	109.0	COG0711@1|root,COG0711@2|Bacteria,1FDW3@1090|Chlorobi	1090|Chlorobi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
LZS3_k127_1485641_15	1075399.BLBCPU_530	0.0003092	53.0	COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,1I53G@117743|Flavobacteriia,3IVK8@39782|Blattabacteriaceae	976|Bacteroidetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
LZS3_k127_1485641_9	1191523.MROS_0276	1.274e-56	212.0	COG0356@1|root,COG0356@2|Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
LZS3_k127_1485641_16	291985.CCSI01000001_gene2600	0.0005261	46.0	COG5336@1|root,COG5336@2|Bacteria,1N2ME@1224|Proteobacteria,2UCBR@28211|Alphaproteobacteria,2K62W@204457|Sphingomonadales	204457|Sphingomonadales	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
LZS3_k127_1485641_8	207559.Dde_2029	2.301e-71	256.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2M8CP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS3_k127_1486648_7	234267.Acid_6604	2.354e-11	65.0	COG1413@1|root,COG1413@2|Bacteria,3Y6AH@57723|Acidobacteria	57723|Acidobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
LZS3_k127_1486648_0	234267.Acid_0588	9.474e-205	648.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
LZS3_k127_1486648_8	1267535.KB906767_gene5115	1.229e-10	67.0	COG2823@1|root,COG2823@2|Bacteria,3Y8T3@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
LZS3_k127_1486648_4	234267.Acid_7714	3.26e-96	326.0	COG1159@1|root,COG1159@2|Bacteria,3Y2GE@57723|Acidobacteria	57723|Acidobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
LZS3_k127_1486648_3	1267535.KB906767_gene5117	1.504e-102	349.0	COG1253@1|root,COG1253@2|Bacteria,3Y3MC@57723|Acidobacteria,2JIF9@204432|Acidobacteriia	204432|Acidobacteriia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
LZS3_k127_1486648_5	234267.Acid_7712	6.327e-32	129.0	COG0319@1|root,COG0319@2|Bacteria,3Y53R@57723|Acidobacteria	57723|Acidobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
LZS3_k127_1486648_2	234267.Acid_7711	1.921e-134	438.0	COG1702@1|root,COG1702@2|Bacteria,3Y3RM@57723|Acidobacteria	57723|Acidobacteria	T	PFAM PhoH family protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
LZS3_k127_1486648_1	1267535.KB906767_gene1239	5.194e-143	464.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_7,DLH,Peptidase_S9
LZS3_k127_1486648_10	1089547.KB913013_gene1310	7.552e-06	55.0	COG1629@1|root,COG1629@2|Bacteria,4NF88@976|Bacteroidetes,47JEF@768503|Cytophagia	976|Bacteroidetes	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3
LZS3_k127_1486648_6	520709.F985_03245	5.233e-28	115.0	2DNZB@1|root,32ZW6@2|Bacteria,1QMYQ@1224|Proteobacteria,1TM15@1236|Gammaproteobacteria,3NPJ4@468|Moraxellaceae	1236|Gammaproteobacteria	S	Cysteine-rich CPCC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPCC
LZS3_k127_1490427_1	1267535.KB906767_gene7	1.482e-213	683.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS
LZS3_k127_1490427_0	234267.Acid_3484	0.0	1088.0	COG0457@1|root,COG0457@2|Bacteria,3Y2Q7@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
LZS3_k127_1644518_0	1121403.AUCV01000012_gene4116	7.205e-244	762.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2MI5G@213118|Desulfobacterales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS3_k127_1644518_1	1267535.KB906767_gene3229	2.117e-178	565.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria,2JJ0A@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
LZS3_k127_1644518_2	247490.KSU1_C0714	2.96e-151	507.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
LZS3_k127_1644518_4	626418.bglu_1g23100	6.735e-09	63.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2VI1Z@28216|Betaproteobacteria,1K385@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Di-haem cytochrome c peroxidase	ccp	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS3_k127_1644518_3	235909.GK2149	7.206e-35	137.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,1WEBS@129337|Geobacillus	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS3_k127_1662867_10	1340493.JNIF01000003_gene1392	1.509e-76	271.0	COG0515@1|root,COG0515@2|Bacteria	1340493.JNIF01000003_gene1392|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1662867_6	1382306.JNIM01000001_gene2669	2.589e-99	346.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_1662867_4	1267535.KB906767_gene3349	7.909e-141	455.0	COG1063@1|root,COG1063@2|Bacteria,3Y6II@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_1662867_13	880070.Cycma_1900	3.143e-69	251.0	COG3616@1|root,COG3616@2|Bacteria	2|Bacteria	E	Alanine racemase, N-terminal domain	dhaa	-	4.1.2.42,4.1.3.41	ko:K18425,ko:K19967	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
LZS3_k127_1662867_14	234267.Acid_3440	1.656e-67	236.0	28NN4@1|root,2ZBNJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1662867_21	1069080.KB913028_gene1707	1.091e-20	105.0	COG1086@1|root,COG1086@2|Bacteria,1U3RH@1239|Firmicutes,4H5VJ@909932|Negativicutes	909932|Negativicutes	GM	Methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
LZS3_k127_1662867_2	861299.J421_0786	2.009e-167	554.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZT4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
LZS3_k127_1662867_24	1463934.JOCF01000081_gene5657	6.89e-10	70.0	COG0346@1|root,COG0346@2|Bacteria,2IHXI@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
LZS3_k127_1662867_11	1340493.JNIF01000003_gene4762	3.938e-73	258.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C,PA14
LZS3_k127_1662867_5	234267.Acid_7883	2.101e-117	396.0	COG1432@1|root,COG1432@2|Bacteria,3Y64C@57723|Acidobacteria	57723|Acidobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
LZS3_k127_1662867_20	1340493.JNIF01000003_gene2471	5.553e-24	106.0	2EE2F@1|root,337X5@2|Bacteria,3Y5GQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1662867_3	1340493.JNIF01000003_gene4457	3.307e-144	472.0	COG1167@1|root,COG1167@2|Bacteria,3Y3WK@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
LZS3_k127_1662867_19	1340493.JNIF01000003_gene4456	5.858e-25	108.0	COG1917@1|root,COG1917@2|Bacteria,3Y93N@57723|Acidobacteria	57723|Acidobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_1662867_18	1403819.BATR01000004_gene133	5.459e-31	128.0	COG2259@1|root,COG2259@2|Bacteria,46WDH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1662867_25	1198114.AciX9_1289	1.809e-09	63.0	2CBGA@1|root,32RQS@2|Bacteria,3Y57E@57723|Acidobacteria,2JJT7@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1662867_7	234267.Acid_7145	1.031e-91	323.0	COG2204@1|root,COG2204@2|Bacteria,3Y6BK@57723|Acidobacteria	57723|Acidobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
LZS3_k127_1662867_12	234267.Acid_6207	1.467e-71	254.0	COG1191@1|root,COG1191@2|Bacteria,3Y6IE@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
LZS3_k127_1662867_0	204669.Acid345_4656	2.5e-237	768.0	COG0272@1|root,COG0272@2|Bacteria,3Y2UR@57723|Acidobacteria,2JHN1@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS3_k127_1662867_17	1267535.KB906767_gene2508	3.248e-52	210.0	COG1597@1|root,COG1597@2|Bacteria,3Y58A@57723|Acidobacteria,2JP23@204432|Acidobacteriia	204432|Acidobacteriia	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
LZS3_k127_1662867_16	234267.Acid_2715	2.472e-58	224.0	COG1988@1|root,COG1988@2|Bacteria,3Y305@57723|Acidobacteria	57723|Acidobacteria	S	membrane-bound metal-dependent hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
LZS3_k127_1662867_22	1408254.T458_08445	1.874e-10	69.0	COG1238@1|root,COG1238@2|Bacteria,1V63I@1239|Firmicutes,4HHFZ@91061|Bacilli,26W23@186822|Paenibacillaceae	91061|Bacilli	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS3_k127_1662867_9	530564.Psta_2542	3.358e-86	302.0	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_1662867_15	196490.AUEZ01000036_gene6081	5.744e-62	230.0	COG3828@1|root,COG3828@2|Bacteria,1R5XA@1224|Proteobacteria,2U51F@28211|Alphaproteobacteria,3K5VQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	GSDH,ThuA
LZS3_k127_1662867_1	909663.KI867150_gene357	5.872e-227	724.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MR6X@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS3_k127_1662867_8	1033743.CAES01000009_gene1904	1.073e-88	303.0	COG0001@1|root,COG0001@2|Bacteria,1V0P3@1239|Firmicutes,4HUXC@91061|Bacilli,26U1F@186822|Paenibacillaceae	91061|Bacilli	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS3_k127_167673_1	1120956.JHZK01000001_gene3449	4.468e-298	931.0	29ISC@1|root,2Z7VE@2|Bacteria,1MWUK@1224|Proteobacteria,2TTFU@28211|Alphaproteobacteria,1JPZS@119043|Rhodobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
LZS3_k127_167673_5	204669.Acid345_0056	8.537e-172	566.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3V0@57723|Acidobacteria,2JHN3@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
LZS3_k127_167673_3	1121374.KB891575_gene1258	4.551e-196	620.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	iECH74115_1262.ECH74115_2481,iECSP_1301.ECSP_2329,iECs_1301.ECs2467,iG2583_1286.G2583_2207,iPC815.YPO3971,iSDY_1059.SDY_1514,iYL1228.KPN_01210,iZ_1308.Z2793	ELFV_dehydrog,ELFV_dehydrog_N
LZS3_k127_167673_11	246194.CHY_1273	7.012e-41	162.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia,42G3H@68295|Thermoanaerobacterales	186801|Clostridia	K	Transcriptional regulator IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
LZS3_k127_167673_0	1267535.KB906767_gene223	2.95e-311	989.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_167673_6	886377.Murru_2673	1.129e-106	353.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
LZS3_k127_167673_7	344747.PM8797T_26465	6.21e-105	353.0	COG2706@1|root,COG2706@2|Bacteria,2IY02@203682|Planctomycetes	203682|Planctomycetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
LZS3_k127_167673_12	335543.Sfum_3204	4.793e-26	114.0	COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,430JJ@68525|delta/epsilon subdivisions,2WVQQ@28221|Deltaproteobacteria,2MRZH@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
LZS3_k127_167673_4	641524.ADICYQ_0168	9.515e-183	585.0	COG5476@1|root,COG5476@2|Bacteria,4NKYT@976|Bacteroidetes,47XQY@768503|Cytophagia	976|Bacteroidetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
LZS3_k127_167673_8	234267.Acid_7929	3.06e-91	310.0	COG0491@1|root,COG0491@2|Bacteria,3Y4DN@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_167673_9	234267.Acid_7931	1.336e-67	242.0	COG0354@1|root,COG0354@2|Bacteria,3Y2PI@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
LZS3_k127_167673_10	1267535.KB906767_gene2969	3.789e-53	196.0	COG0631@1|root,COG0631@2|Bacteria,3Y4SV@57723|Acidobacteria,2JJFU@204432|Acidobacteriia	204432|Acidobacteriia	T	Protein phosphatase 2C	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS3_k127_167673_15	641491.DND132_1914	2.733e-06	55.0	COG1639@1|root,COG1639@2|Bacteria,1RKNA@1224|Proteobacteria,42TE8@68525|delta/epsilon subdivisions,2WPCE@28221|Deltaproteobacteria,2M9GH@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
LZS3_k127_167673_2	234267.Acid_0069	1.679e-243	786.0	COG1391@1|root,COG1391@2|Bacteria,3Y72J@57723|Acidobacteria	57723|Acidobacteria	H	Glutamate-ammonia ligase adenylyltransferase	-	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
LZS3_k127_1776813_2	234267.Acid_0264	1.482e-147	487.0	COG1044@1|root,COG1044@2|Bacteria,3Y4K5@57723|Acidobacteria	57723|Acidobacteria	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
LZS3_k127_1776813_0	234267.Acid_0265	3.497e-191	629.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906,VCBS
LZS3_k127_1776813_6	1122194.AUHU01000003_gene2083	4.046e-67	238.0	COG0668@1|root,COG0668@2|Bacteria,1Q8BJ@1224|Proteobacteria,1S0HZ@1236|Gammaproteobacteria,46CZW@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS3_k127_1776813_5	1267535.KB906767_gene3534	2.763e-82	297.0	COG0760@1|root,COG0760@2|Bacteria,3Y3BW@57723|Acidobacteria,2JIP1@204432|Acidobacteriia	204432|Acidobacteriia	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
LZS3_k127_1776813_1	1144275.COCOR_03626	2.792e-150	495.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
LZS3_k127_1776813_9	1267535.KB906767_gene9	6.118e-10	65.0	COG0810@1|root,COG0810@2|Bacteria,3Y4BU@57723|Acidobacteria,2JJ3R@204432|Acidobacteriia	204432|Acidobacteriia	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
LZS3_k127_1776813_4	1267535.KB906767_gene1161	1.225e-92	318.0	COG1921@1|root,COG1921@2|Bacteria	2|Bacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
LZS3_k127_1776813_3	234267.Acid_7823	1.509e-107	359.0	COG2017@1|root,COG2017@2|Bacteria,3Y4YM@57723|Acidobacteria	57723|Acidobacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1776813_8	2045.KR76_26530	5.922e-12	70.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4DNDD@85009|Propionibacteriales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS3_k127_1776813_10	28176.CF66_2044	5.305e-05	49.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1XSPW@135623|Vibrionales	135623|Vibrionales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS3_k127_1778952_4	204669.Acid345_0001	8.455e-33	133.0	COG0593@1|root,COG0593@2|Bacteria,3Y2HA@57723|Acidobacteria,2JHN7@204432|Acidobacteriia	204432|Acidobacteriia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS3_k127_1778952_3	1177154.Y5S_00615	7.625e-36	139.0	COG1474@1|root,COG1474@2|Bacteria,1MX0Q@1224|Proteobacteria,1RQSI@1236|Gammaproteobacteria,1XMWW@135619|Oceanospirillales	135619|Oceanospirillales	LO	DNA polymerase III	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
LZS3_k127_1778952_7	555779.Dthio_PD2105	6.707e-07	57.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,43B03@68525|delta/epsilon subdivisions,2X6E6@28221|Deltaproteobacteria,2MH1Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
LZS3_k127_1778952_6	399739.Pmen_0080	1.38e-15	78.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,1SGD7@1236|Gammaproteobacteria,1YH07@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	UPF0391 membrane protein	ytjA	-	-	-	-	-	-	-	-	-	-	-	DUF1328
LZS3_k127_1778952_2	247490.KSU1_C0634	3.19e-58	216.0	COG0628@1|root,COG0628@2|Bacteria,2J2TA@203682|Planctomycetes	203682|Planctomycetes	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS3_k127_1778952_5	1266925.JHVX01000001_gene2456	1.255e-22	103.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2VH0E@28216|Betaproteobacteria,373K9@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_1778952_8	1280947.HY30_03885	0.0006279	48.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,43WCX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	COG0744 Membrane carboxypeptidase (penicillin-binding protein)	pbp	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
LZS3_k127_1778952_1	204669.Acid345_1065	1.199e-59	215.0	COG0744@1|root,COG0744@2|Bacteria,3Y42I@57723|Acidobacteria,2JI7Q@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
LZS3_k127_1778952_0	1267535.KB906767_gene5335	2.915e-140	458.0	COG3328@1|root,COG3328@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Transposase_mut
LZS3_k127_1791605_5	234267.Acid_4835	3.42e-85	287.0	COG1573@1|root,COG1573@2|Bacteria,3Y4AT@57723|Acidobacteria	57723|Acidobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS3_k127_1791605_10	1267535.KB906767_gene4881	1.323e-17	90.0	COG1734@1|root,COG1734@2|Bacteria,3Y85W@57723|Acidobacteria	57723|Acidobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS3_k127_1791605_6	234267.Acid_6578	2.215e-36	142.0	COG0251@1|root,COG0251@2|Bacteria,3Y8KT@57723|Acidobacteria	57723|Acidobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
LZS3_k127_1791605_2	357808.RoseRS_3113	1.765e-185	588.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi,375CE@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS3_k127_1791605_7	1211112.ALJC01000075_gene3056	1.011e-22	107.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,1S3H1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
LZS3_k127_1791605_3	926554.KI912627_gene1165	6.946e-125	409.0	COG3173@1|root,COG3173@2|Bacteria,1WJ1R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
LZS3_k127_1791605_11	2423.NA23_0205735	3.819e-12	71.0	COG1555@1|root,COG1555@2|Bacteria,2GD8U@200918|Thermotogae	200918|Thermotogae	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
LZS3_k127_1791605_8	1121918.ARWE01000001_gene2237	1.248e-20	102.0	COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,42PJR@68525|delta/epsilon subdivisions,2WPBQ@28221|Deltaproteobacteria,43UP6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
LZS3_k127_1791605_0	1267535.KB906767_gene2115	0.0	1038.0	COG0556@1|root,COG0556@2|Bacteria,3Y31K@57723|Acidobacteria,2JHY9@204432|Acidobacteriia	204432|Acidobacteriia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
LZS3_k127_1791605_1	234267.Acid_4968	9.227e-190	621.0	COG0308@1|root,COG0308@2|Bacteria,3Y31F@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
LZS3_k127_1791605_4	234267.Acid_3254	6.824e-121	397.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_1791605_9	682795.AciX8_3257	4.774e-19	94.0	COG3485@1|root,COG3485@2|Bacteria,3Y3R9@57723|Acidobacteria,2JHNH@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_1839935_1	1122137.AQXF01000003_gene2094	2.82e-84	297.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,2VGDT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS3_k127_1839935_0	1249627.D779_2280	2.538e-122	412.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1WWYZ@135613|Chromatiales	135613|Chromatiales	E	PFAM Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
LZS3_k127_1839935_2	717606.PaecuDRAFT_1144	8.683e-66	232.0	2DBMF@1|root,2Z9YG@2|Bacteria,1VYCA@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1839935_5	1437824.BN940_00211	8.652e-11	64.0	COG2337@1|root,COG2337@2|Bacteria,1N0JV@1224|Proteobacteria,2VV5S@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
LZS3_k127_1839935_6	118173.KB235914_gene2798	3.188e-05	47.0	2EAQB@1|root,334SJ@2|Bacteria,1GF8A@1117|Cyanobacteria,1HGBB@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1839935_4	234267.Acid_4830	3.08e-39	169.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1900304_1	1267535.KB906767_gene719	1.074e-156	499.0	COG1262@1|root,COG1262@2|Bacteria,3Y4J6@57723|Acidobacteria,2JM73@204432|Acidobacteriia	204432|Acidobacteriia	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS3_k127_1900304_3	1267535.KB906767_gene720	8.828e-71	250.0	COG0760@1|root,COG0760@2|Bacteria,3Y8EB@57723|Acidobacteria,2JNN9@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM PPIC-type	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
LZS3_k127_1900304_4	456442.Mboo_0852	1.376e-14	77.0	COG1598@1|root,arCOG02412@2157|Archaea	2157|Archaea	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1900304_5	388467.A19Y_1337	7.211e-06	52.0	COG1724@1|root,COG1724@2|Bacteria,1G7VM@1117|Cyanobacteria,1HGH4@1150|Oscillatoriales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
LZS3_k127_1900304_0	379066.GAU_3508	1.01e-203	647.0	COG4584@1|root,COG4584@2|Bacteria,1ZV8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
LZS3_k127_1900304_2	379066.GAU_3509	7.747e-108	356.0	COG1484@1|root,COG1484@2|Bacteria,1ZV5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
LZS3_k127_1954609_12	234267.Acid_6604	2.488e-96	330.0	COG1413@1|root,COG1413@2|Bacteria,3Y6AH@57723|Acidobacteria	57723|Acidobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
LZS3_k127_1954609_10	1340493.JNIF01000003_gene2827	2.064e-109	361.0	COG2107@1|root,COG2107@2|Bacteria,3Y31U@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
LZS3_k127_1954609_24	1267535.KB906767_gene3024	4.464e-18	91.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	frzZ	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_1954609_5	1280952.HJA_06147	1.823e-141	464.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,HemolysinCabind,VCBS
LZS3_k127_1954609_15	1267535.KB906767_gene3961	4.776e-68	243.0	COG1409@1|root,COG1409@2|Bacteria,3Y7IU@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_1954609_23	1033810.HLPCO_001631	3.295e-22	102.0	COG2314@1|root,COG2314@2|Bacteria,2NRTY@2323|unclassified Bacteria	2|Bacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
LZS3_k127_1954609_25	1120949.KB903303_gene6694	4.86e-17	93.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,4DB5S@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.361	ko:K18652	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_1954609_18	1201288.M900_2565	1.831e-39	163.0	COG0621@1|root,COG0621@2|Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.3,2.8.4.5	ko:K06168,ko:K18707	-	-	R10645,R10646,R10647,R10649	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
LZS3_k127_1954609_9	344747.PM8797T_27502	1.045e-109	370.0	COG4409@1|root,COG4409@2|Bacteria,2J2E2@203682|Planctomycetes	203682|Planctomycetes	G	Neuraminidase (sialidase)	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
LZS3_k127_1954609_2	204669.Acid345_1052	7.265e-154	516.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
LZS3_k127_1954609_7	344747.PM8797T_15948	6.287e-135	443.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_1954609_4	234267.Acid_7134	7.306e-145	476.0	COG4365@1|root,COG4365@2|Bacteria,3Y4D6@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the BshC family	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
LZS3_k127_1954609_8	234267.Acid_5926	2.807e-121	400.0	COG0635@1|root,COG0635@2|Bacteria,3Y2ZB@57723|Acidobacteria	57723|Acidobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
LZS3_k127_1954609_26	1340493.JNIF01000003_gene2185	2.406e-14	76.0	COG2197@1|root,COG2197@2|Bacteria,3Y2WY@57723|Acidobacteria	57723|Acidobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_1954609_16	383372.Rcas_2743	1.12e-51	198.0	COG2227@1|root,COG2227@2|Bacteria,2GAP4@200795|Chloroflexi,376X2@32061|Chloroflexia	32061|Chloroflexia	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
LZS3_k127_1954609_14	1499967.BAYZ01000050_gene2785	2.402e-87	311.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,2NPQ4@2323|unclassified Bacteria	2|Bacteria	J	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_11
LZS3_k127_1954609_21	1340493.JNIF01000003_gene1837	2.497e-33	136.0	COG0735@1|root,COG0735@2|Bacteria,3Y4W2@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS3_k127_1954609_13	251221.35214867	1.617e-94	312.0	COG2406@1|root,COG2406@2|Bacteria,1G4NT@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the Dps family	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
LZS3_k127_1954609_20	1173026.Glo7428_2182	1.719e-33	132.0	COG2146@1|root,COG2146@2|Bacteria,1G9AZ@1117|Cyanobacteria	1117|Cyanobacteria	P	of nitrite reductase and ring-hydroxylating dioxygenase	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
LZS3_k127_1954609_19	266117.Rxyl_2043	2.07e-39	149.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
LZS3_k127_1954609_11	344747.PM8797T_21408	4.182e-100	340.0	COG1520@1|root,COG1520@2|Bacteria,2IYZY@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_1954609_6	344747.PM8797T_21413	2.256e-138	452.0	COG1454@1|root,COG1454@2|Bacteria,2IXD7@203682|Planctomycetes	203682|Planctomycetes	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
LZS3_k127_1954609_3	1210884.HG799464_gene11021	1.002e-152	490.0	COG1541@1|root,COG1541@2|Bacteria,2IWUR@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1954609_0	756272.Plabr_1285	3.651e-186	593.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_1954609_1	344747.PM8797T_21603	2.06e-175	575.0	COG1520@1|root,COG1520@2|Bacteria,2IX37@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_1954609_22	234267.Acid_7858	7.464e-26	112.0	2C8EQ@1|root,3497J@2|Bacteria,3Y8QF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1954609_17	234267.Acid_7859	1.024e-42	162.0	COG1565@1|root,COG1565@2|Bacteria,3Y583@57723|Acidobacteria	57723|Acidobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
LZS3_k127_1983132_8	1232410.KI421412_gene454	5.416e-60	210.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,43SKN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	D-Tyr-tRNA(Tyr) deacylase	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
LZS3_k127_1983132_13	234267.Acid_4758	4.143e-10	63.0	2C7DG@1|root,2ZTXV@2|Bacteria,3Y94Z@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1983132_5	234267.Acid_0954	5.908e-86	299.0	COG1408@1|root,COG1408@2|Bacteria,3Y5PS@57723|Acidobacteria	57723|Acidobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
LZS3_k127_1983132_6	234267.Acid_0953	5.812e-74	257.0	COG0639@1|root,COG0639@2|Bacteria,3Y3U2@57723|Acidobacteria	57723|Acidobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
LZS3_k127_1983132_7	204669.Acid345_1150	5.614e-69	243.0	arCOG09454@1|root,31B41@2|Bacteria,3Y8HD@57723|Acidobacteria,2JNG1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1983132_0	1382356.JQMP01000001_gene1242	1.799e-178	567.0	COG1454@1|root,COG1454@2|Bacteria,2G6IU@200795|Chloroflexi,27YUC@189775|Thermomicrobia	189775|Thermomicrobia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.99.24	ko:K11173	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
LZS3_k127_1983132_11	998674.ATTE01000001_gene213	1.227e-32	132.0	COG0393@1|root,COG0393@2|Bacteria,1N6BK@1224|Proteobacteria,1SAFJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS3_k127_1983132_10	1173029.JH980292_gene4214	2.346e-42	157.0	COG0393@1|root,COG0393@2|Bacteria,1G7AD@1117|Cyanobacteria,1HC1G@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS3_k127_1983132_4	1340493.JNIF01000003_gene4604	3.161e-96	327.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	DUF3500
LZS3_k127_1983132_1	56110.Oscil6304_3528	2.432e-115	383.0	COG0451@1|root,COG0451@2|Bacteria,1G0QH@1117|Cyanobacteria,1H7R6@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	4.1.1.35,5.1.3.2	ko:K01784,ko:K08678	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01384,R02984	RC00289,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS3_k127_1983132_2	373994.Riv7116_2168	2.135e-112	376.0	COG0438@1|root,COG0438@2|Bacteria,1G4DC@1117|Cyanobacteria,1HQ2H@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
LZS3_k127_1983132_3	1142394.PSMK_05030	4.393e-111	366.0	COG0388@1|root,COG0388@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
LZS3_k127_1983132_9	1142394.PSMK_05040	7.674e-54	198.0	COG0388@1|root,COG0388@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_1983132_12	1265313.HRUBRA_00780	1.697e-14	81.0	COG2133@1|root,COG2133@2|Bacteria,1R8DY@1224|Proteobacteria	1224|Proteobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_199263_12	867903.ThesuDRAFT_00902	2.62e-10	65.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WD7W@538999|Clostridiales incertae sedis	186801|Clostridia	GK	Transcriptional regulator sugar kinase	-	-	-	-	-	-	-	-	-	-	-	-	ROK
LZS3_k127_199263_1	443143.GM18_4243	1.596e-98	333.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,42M3Z@68525|delta/epsilon subdivisions,2WJIR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
LZS3_k127_199263_11	1340493.JNIF01000003_gene1455	1.9e-20	100.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
LZS3_k127_199263_8	1434929.X946_2570	3.57e-35	145.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,2VJR1@28216|Betaproteobacteria,1K0XF@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
LZS3_k127_199263_6	1340493.JNIF01000003_gene4446	6.171e-47	181.0	COG2087@1|root,COG2087@2|Bacteria,3Y746@57723|Acidobacteria	57723|Acidobacteria	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	-	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
LZS3_k127_199263_2	1340493.JNIF01000003_gene4444	3.639e-87	298.0	COG0609@1|root,COG0609@2|Bacteria,3Y7KJ@57723|Acidobacteria	57723|Acidobacteria	P	FecCD transport family	-	-	-	-	-	-	-	-	-	-	-	-	FecCD
LZS3_k127_199263_5	268739.Nmlp_3091	6.819e-54	202.0	COG1120@1|root,arCOG00199@2157|Archaea,2XTTV@28890|Euryarchaeota,23SRW@183963|Halobacteria	183963|Halobacteria	E	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components	btuD	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
LZS3_k127_199263_4	1340493.JNIF01000003_gene4442	1.059e-69	248.0	COG0614@1|root,COG0614@2|Bacteria,3Y7Z8@57723|Acidobacteria	57723|Acidobacteria	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
LZS3_k127_199263_0	1340493.JNIF01000003_gene4439	1.587e-144	476.0	COG1492@1|root,COG1492@2|Bacteria,3Y64K@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
LZS3_k127_199263_9	886293.Sinac_2108	4.601e-34	138.0	COG5485@1|root,COG5485@2|Bacteria,2J0V1@203682|Planctomycetes	203682|Planctomycetes	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
LZS3_k127_199263_3	1121022.ABENE_12395	3.968e-86	295.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,2KHRA@204458|Caulobacterales	204458|Caulobacterales	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
LZS3_k127_199263_7	266265.Bxe_A0367	2.661e-46	175.0	2CGTY@1|root,32S4K@2|Bacteria,1N4C2@1224|Proteobacteria,2WCZ5@28216|Betaproteobacteria,1K8TT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_199263_10	1297569.MESS2_130038	9.932e-27	118.0	COG1848@1|root,COG1848@2|Bacteria,1NDJE@1224|Proteobacteria,2UHGN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_199263_13	216432.CA2559_06360	1.841e-05	52.0	2FDT9@1|root,345TZ@2|Bacteria,4P5PU@976|Bacteroidetes,1IAD0@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2022471_3	1565129.JSFF01000017_gene2952	3.391e-42	160.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q8ZE@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS3_k127_2022471_4	660470.Theba_0308	5.299e-27	123.0	COG2035@1|root,COG2035@2|Bacteria,2GDA0@200918|Thermotogae	200918|Thermotogae	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
LZS3_k127_2022471_1	886293.Sinac_6965	2.358e-104	365.0	COG0739@1|root,COG1506@1|root,COG3291@1|root,COG0739@2|Bacteria,COG1506@2|Bacteria,COG3291@2|Bacteria,2IYE5@203682|Planctomycetes	203682|Planctomycetes	E	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
LZS3_k127_2022471_5	1340493.JNIF01000003_gene3608	4.997e-12	80.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Lectin_C
LZS3_k127_2022471_0	1123248.KB893339_gene2701	1.051e-124	432.0	COG4932@1|root,COG5276@1|root,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_3_2,Big_3_5,Big_5,DUF3494
LZS3_k127_2022471_2	378806.STAUR_3895	5.24e-50	204.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,1R85W@1224|Proteobacteria	1224|Proteobacteria	M	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
LZS3_k127_203924_5	234267.Acid_2629	4.341e-22	112.0	COG3485@1|root,COG3485@2|Bacteria,3Y9A8@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_203924_6	391625.PPSIR1_12803	6.582e-05	55.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_203924_0	234267.Acid_4748	7.166e-148	485.0	COG1858@1|root,COG1858@2|Bacteria,3Y7FY@57723|Acidobacteria	57723|Acidobacteria	P	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
LZS3_k127_203924_1	234267.Acid_7665	8.385e-85	305.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
LZS3_k127_203924_2	1340493.JNIF01000003_gene1755	3.935e-60	227.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_203924_3	330214.NIDE1190	1.991e-55	203.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS3_k127_203924_4	314230.DSM3645_21432	6.932e-44	166.0	COG0025@1|root,COG0025@2|Bacteria,2IX74@203682|Planctomycetes	203682|Planctomycetes	P	COG0025 NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
LZS3_k127_218309_3	234267.Acid_5201	3.687e-102	343.0	COG1477@1|root,COG1477@2|Bacteria,3Y4B0@57723|Acidobacteria	57723|Acidobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
LZS3_k127_218309_7	1267535.KB906767_gene3291	2.624e-21	96.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
LZS3_k127_218309_0	234267.Acid_5181	4.826e-288	912.0	COG0532@1|root,COG3266@1|root,COG0532@2|Bacteria,COG3266@2|Bacteria,3Y3UG@57723|Acidobacteria	57723|Acidobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
LZS3_k127_218309_2	234267.Acid_5180	6.616e-182	586.0	COG0195@1|root,COG0195@2|Bacteria,3Y379@57723|Acidobacteria	57723|Acidobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
LZS3_k127_218309_6	204669.Acid345_4219	9.418e-42	158.0	COG0779@1|root,COG0779@2|Bacteria,3Y528@57723|Acidobacteria,2JJHJ@204432|Acidobacteriia	204432|Acidobacteriia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
LZS3_k127_218309_4	234267.Acid_2233	1.305e-93	315.0	COG1082@1|root,COG1082@2|Bacteria,3Y2PT@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_218309_5	556267.HWAG_01508	1.389e-52	196.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2YMY7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
LZS3_k127_218309_1	986075.CathTA2_2241	1.815e-184	593.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli	91061|Bacilli	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
LZS3_k127_2242934_2	1173026.Glo7428_3942	4.051e-52	195.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
LZS3_k127_2242934_3	485913.Krac_1511	4.858e-38	148.0	COG3316@1|root,COG3316@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
LZS3_k127_2242934_0	1434325.AZQN01000003_gene2832	9.136e-275	861.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,47P31@768503|Cytophagia	976|Bacteroidetes	P	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14,Sulfatase
LZS3_k127_2242934_1	1267534.KB906754_gene3673	2.358e-115	382.0	28HBM@1|root,2Z7NK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2248264_10	1267535.KB906767_gene4164	3.825e-11	64.0	COG1722@1|root,COG1722@2|Bacteria,3Y5RT@57723|Acidobacteria	57723|Acidobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
LZS3_k127_2248264_5	1460635.JCM19038_788	4.448e-112	371.0	COG0826@1|root,COG0826@2|Bacteria,1TT8S@1239|Firmicutes,4HCNE@91061|Bacilli	91061|Bacilli	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
LZS3_k127_2248264_4	234267.Acid_0902	1.147e-112	370.0	COG0083@1|root,COG0083@2|Bacteria,3Y2ZV@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS3_k127_2248264_7	1340493.JNIF01000003_gene1333	1.842e-46	183.0	COG4963@1|root,COG4963@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
LZS3_k127_2248264_1	1382359.JIAL01000001_gene2525	1.145e-137	446.0	COG2957@1|root,COG2957@2|Bacteria,3Y2W5@57723|Acidobacteria,2JIKF@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
LZS3_k127_2248264_2	886293.Sinac_3542	7.657e-131	425.0	COG0388@1|root,COG0388@2|Bacteria,2IX91@203682|Planctomycetes	203682|Planctomycetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
LZS3_k127_2248264_6	234267.Acid_0312	2.573e-70	244.0	COG1595@1|root,COG1595@2|Bacteria,3Y2V2@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_2248264_8	234267.Acid_0315	1.891e-46	178.0	COG1514@1|root,COG1514@2|Bacteria,3Y5S7@57723|Acidobacteria	57723|Acidobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
LZS3_k127_2248264_3	234267.Acid_1510	3.001e-127	429.0	COG3485@1|root,COG3485@2|Bacteria,3Y44E@57723|Acidobacteria	57723|Acidobacteria	Q	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_2248264_0	1340493.JNIF01000003_gene4121	2.447e-199	636.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2260687_33	1232410.KI421413_gene484	1.151e-25	108.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,437CT@68525|delta/epsilon subdivisions,2XA0U@28221|Deltaproteobacteria,43VKC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
LZS3_k127_2260687_1	639282.DEFDS_0463	2.354e-268	843.0	COG3808@1|root,COG3808@2|Bacteria,2GFAJ@200930|Deferribacteres	200930|Deferribacteres	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
LZS3_k127_2260687_17	1340493.JNIF01000003_gene3849	3.127e-82	285.0	COG2304@1|root,COG2304@2|Bacteria,3Y6QE@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
LZS3_k127_2260687_22	234267.Acid_6713	5.947e-60	211.0	COG0864@1|root,COG0864@2|Bacteria,3Y83A@57723|Acidobacteria	57723|Acidobacteria	K	NikR C terminal nickel binding domain	-	-	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
LZS3_k127_2260687_19	1120950.KB892756_gene6656	1.503e-62	234.0	COG1312@1|root,COG1312@2|Bacteria,2H319@201174|Actinobacteria,4DS9M@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the dehydration of D-mannonate	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
LZS3_k127_2260687_5	317936.Nos7107_1598	1.616e-168	560.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1HJE5@1161|Nostocales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS3_k127_2260687_8	886293.Sinac_3668	1.746e-137	451.0	COG0534@1|root,COG0534@2|Bacteria,2IX5Q@203682|Planctomycetes	203682|Planctomycetes	V	COG0534 Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
LZS3_k127_2260687_25	552811.Dehly_0440	5.728e-52	192.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
LZS3_k127_2260687_2	1267535.KB906767_gene1021	3.126e-258	812.0	COG0173@1|root,COG0173@2|Bacteria,3Y3SP@57723|Acidobacteria,2JIRC@204432|Acidobacteriia	204432|Acidobacteriia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS3_k127_2260687_27	653045.Strvi_3477	1.972e-45	173.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria	201174|Actinobacteria	K	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
LZS3_k127_2260687_31	1541065.JRFE01000024_gene846	2.592e-29	127.0	COG4293@1|root,COG4293@2|Bacteria,1G555@1117|Cyanobacteria,3VJTM@52604|Pleurocapsales	1117|Cyanobacteria	S	Domain of unknown function (DUF1802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1802
LZS3_k127_2260687_10	234267.Acid_6462	7.653e-112	376.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_4
LZS3_k127_2260687_12	1340493.JNIF01000004_gene438	3.9e-96	318.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria	57723|Acidobacteria	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_2260687_39	502025.Hoch_3247	9.018e-06	59.0	COG0457@1|root,COG0457@2|Bacteria	502025.Hoch_3247|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2260687_20	1123242.JH636434_gene5244	2.362e-62	241.0	2E55N@1|root,32ZYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2260687_13	1028801.RG1141_PA04350	7.815e-91	314.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,4BBEI@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_2260687_11	234267.Acid_7868	1.879e-101	339.0	COG1230@1|root,COG1230@2|Bacteria,3Y32W@57723|Acidobacteria	57723|Acidobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
LZS3_k127_2260687_36	391008.Smal_0515	1.169e-09	71.0	2DXB8@1|root,3447X@2|Bacteria,1P1UM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2260687_23	234267.Acid_0268	4.449e-55	205.0	COG1295@1|root,COG1295@2|Bacteria,3Y4P8@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ribonuclease	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS3_k127_2260687_24	234267.Acid_5883	1.139e-52	189.0	COG1959@1|root,COG1959@2|Bacteria,3Y87Y@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS3_k127_2260687_6	697282.Mettu_2273	3.689e-142	460.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XDN6@135618|Methylococcales	135618|Methylococcales	H	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_2260687_15	1120985.AUMI01000002_gene2392	1.459e-89	306.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,4H4TK@909932|Negativicutes	909932|Negativicutes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_2260687_7	481448.Minf_0010	2.419e-140	461.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS3_k127_2260687_9	234267.Acid_1441	4.698e-115	383.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_2260687_14	234267.Acid_2141	9.077e-91	310.0	COG0111@1|root,COG0111@2|Bacteria,3Y3VD@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
LZS3_k127_2260687_16	234267.Acid_1508	4.223e-89	306.0	COG2421@1|root,COG2421@2|Bacteria	2|Bacteria	C	formamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
LZS3_k127_2260687_18	1288963.ADIS_0328	2.508e-69	251.0	COG1921@1|root,COG1921@2|Bacteria,4NIIG@976|Bacteroidetes,47NJD@768503|Cytophagia	976|Bacteroidetes	E	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
LZS3_k127_2260687_37	1123386.AUIW01000002_gene1258	2.704e-07	56.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	nbaC	GO:0000334,GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0044237,GO:0044248,GO:0051213,GO:0055114	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO,Cupin_2
LZS3_k127_2260687_35	754035.Mesau_04697	7.811e-15	79.0	COG1917@1|root,COG1917@2|Bacteria,1N1ZP@1224|Proteobacteria,2UE27@28211|Alphaproteobacteria,43PMM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Ethanolamine utilisation protein EutQ	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_2260687_40	1267535.KB906767_gene2743	3.552e-05	53.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,PG_binding_1
LZS3_k127_2260687_30	1382359.JIAL01000001_gene2547	3.279e-36	151.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
LZS3_k127_2260687_29	204669.Acid345_2567	1.165e-39	165.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria,2JI98@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_2260687_38	926566.Terro_3558	9.63e-07	57.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria,2JIN1@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS3_k127_2260687_3	1267535.KB906767_gene940	4.872e-209	663.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,3Y3QY@57723|Acidobacteria,2JHPJ@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
LZS3_k127_2260687_32	1232410.KI421413_gene473	4.963e-28	123.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,42VAD@68525|delta/epsilon subdivisions,2WRMT@28221|Deltaproteobacteria,43SM5@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,TehB
LZS3_k127_2260687_28	1267535.KB906767_gene3221	1.975e-44	164.0	COG0316@1|root,COG0316@2|Bacteria,3Y4ZB@57723|Acidobacteria,2JJEX@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the HesB IscA family	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
LZS3_k127_2260687_4	1340493.JNIF01000004_gene1087	6.047e-185	587.0	COG4102@1|root,COG4102@2|Bacteria	1340493.JNIF01000004_gene1087|-	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2260687_0	1340493.JNIF01000004_gene1086	1.557e-288	911.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2
LZS3_k127_2260687_26	1340493.JNIF01000004_gene1085	3.414e-47	179.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K06370	-	-	-	-	ko00000	-	-	-	CW_binding_1,Flg_new,GGDEF,Gram_pos_anchor,LysM,WD40
LZS3_k127_226210_6	234267.Acid_0849	5.226e-50	183.0	COG0494@1|root,COG0494@2|Bacteria,3Y4N9@57723|Acidobacteria	57723|Acidobacteria	L	PFAM NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
LZS3_k127_226210_8	485915.Dret_0243	1.749e-09	71.0	COG0457@1|root,COG0457@2|Bacteria,1R438@1224|Proteobacteria,42PQ9@68525|delta/epsilon subdivisions,2WJ0C@28221|Deltaproteobacteria,2M83F@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
LZS3_k127_226210_2	1121918.ARWE01000001_gene746	1.908e-128	439.0	COG0457@1|root,COG0457@2|Bacteria,1R1JQ@1224|Proteobacteria,4377S@68525|delta/epsilon subdivisions,2WTFW@28221|Deltaproteobacteria,43U9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS3_k127_226210_0	234267.Acid_0848	1.218e-230	727.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,3Y2SH@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase X	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
LZS3_k127_226210_3	1185876.BN8_03987	3.429e-84	295.0	COG2021@1|root,COG2021@2|Bacteria,4NHJ4@976|Bacteroidetes,47NTI@768503|Cytophagia	976|Bacteroidetes	E	alpha/beta hydrolase fold	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
LZS3_k127_226210_5	479434.Sthe_0370	1.583e-50	185.0	2DW90@1|root,33Z49@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_226210_7	452637.Oter_4607	1.953e-45	169.0	COG3005@1|root,COG3005@2|Bacteria,46T0N@74201|Verrucomicrobia,3K8D9@414999|Opitutae	414999|Opitutae	C	TIGRFAM cytochrome c nitrate reductase, small subunit	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
LZS3_k127_226210_1	247490.KSU1_B0055	8.653e-183	580.0	COG3303@1|root,COG3303@2|Bacteria,2IYGG@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
LZS3_k127_226210_4	227377.CBU_0773	4.391e-56	201.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,1S5YT@1236|Gammaproteobacteria,1JF2S@118969|Legionellales	118969|Legionellales	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
LZS3_k127_226210_9	1183438.GKIL_2944	8.943e-07	55.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG
LZS3_k127_2268632_0	1267535.KB906767_gene3315	4.402e-281	878.0	COG0627@1|root,COG0627@2|Bacteria,3Y8MG@57723|Acidobacteria	57723|Acidobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
LZS3_k127_2268632_1	1267535.KB906767_gene3453	8.873e-15	79.0	COG0673@1|root,COG0673@2|Bacteria,3Y4RG@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_2270458_24	1082933.MEA186_28762	3.301e-22	98.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.156,4.2.1.42	ko:K20023	ko00053,map00053	-	R05608	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_2270458_27	1094715.CM001373_gene1606	3.993e-09	67.0	COG1073@1|root,COG2885@1|root,COG1073@2|Bacteria,COG2885@2|Bacteria,1RFNW@1224|Proteobacteria,1SBNT@1236|Gammaproteobacteria,1JE7U@118969|Legionellales	118969|Legionellales	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2270458_12	926566.Terro_3979	5.435e-71	255.0	COG0520@1|root,COG0520@2|Bacteria,3Y3UN@57723|Acidobacteria,2JK05@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
LZS3_k127_2270458_5	344747.PM8797T_14594	3.316e-133	441.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_2270458_7	234267.Acid_5626	2.531e-124	432.0	COG5549@1|root,COG5549@2|Bacteria	234267.Acid_5626|-	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2270458_26	1238184.CM001792_gene3223	3.379e-13	82.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli,23KNV@182709|Oceanobacillus	91061|Bacilli	J	Endoribonuclease L-PSP	yabJ	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS3_k127_2270458_25	518766.Rmar_0815	2.125e-21	108.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,1FJEF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Endoribonuclease L-PSP	yjgF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS3_k127_2270458_4	497964.CfE428DRAFT_4945	2.1e-139	456.0	COG1541@1|root,COG1541@2|Bacteria,46SVW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
LZS3_k127_2270458_18	497964.CfE428DRAFT_4947	5.717e-41	157.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
LZS3_k127_2270458_2	497964.CfE428DRAFT_5041	1.371e-169	541.0	COG0644@1|root,COG0644@2|Bacteria,46U5W@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
LZS3_k127_2270458_22	1403819.BATR01000118_gene4175	3.032e-25	113.0	COG3161@1|root,COG3161@2|Bacteria,46WDJ@74201|Verrucomicrobia	74201|Verrucomicrobia	H	chorismate lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2270458_1	240016.ABIZ01000001_gene3202	7.232e-171	550.0	COG0635@1|root,COG0635@2|Bacteria,46U2R@74201|Verrucomicrobia,2IWKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS3_k127_2270458_21	1173023.KE650771_gene413	3.327e-34	140.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria,1JIJJ@1189|Stigonemataceae	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_2270458_3	1123508.JH636447_gene8042	6.331e-159	547.0	COG0457@1|root,COG0457@2|Bacteria	1123508.JH636447_gene8042|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2270458_0	886293.Sinac_7278	4.469e-202	652.0	COG4993@1|root,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
LZS3_k127_2270458_29	452863.Achl_2644	6.672e-07	60.0	COG4961@1|root,COG4961@2|Bacteria,2IS3K@201174|Actinobacteria	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS3_k127_2270458_30	1121456.ATVA01000014_gene768	4.589e-06	57.0	COG4961@1|root,COG4961@2|Bacteria,1PZKX@1224|Proteobacteria,42XHM@68525|delta/epsilon subdivisions,2X24C@28221|Deltaproteobacteria,2MD5I@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS3_k127_2270458_19	526225.Gobs_0746	1.407e-38	151.0	COG1262@1|root,COG3170@1|root,COG1262@2|Bacteria,COG3170@2|Bacteria,2IBYZ@201174|Actinobacteria	201174|Actinobacteria	NU	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	PknH_C,TIR_2
LZS3_k127_2270458_11	1250232.JQNJ01000001_gene3548	2.134e-71	252.0	2EWAU@1|root,33PPI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2270458_31	1530186.JQEY01000001_gene893	0.0006215	44.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS3_k127_2270458_13	661478.OP10G_0756	3.352e-50	187.0	COG0745@1|root,COG0745@2|Bacteria	661478.OP10G_0756|-	T	phosphorelay signal transduction system	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
LZS3_k127_2270458_8	671143.DAMO_0479	1.017e-117	387.0	COG3437@1|root,COG3437@2|Bacteria,2NPBP@2323|unclassified Bacteria	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
LZS3_k127_2270458_9	395493.BegalDRAFT_1106	9.559e-114	408.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,1T2D4@1236|Gammaproteobacteria,463V1@72273|Thiotrichales	1236|Gammaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF,HATPase_c,HisKA,Response_reg
LZS3_k127_2270458_20	1267535.KB906767_gene2892	2.824e-34	135.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	divK	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
LZS3_k127_2270458_10	269482.Bcep1808_6110	2.536e-100	337.0	COG1388@1|root,COG1388@2|Bacteria,1MY1S@1224|Proteobacteria,2VZIM@28216|Betaproteobacteria,1K4M4@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Domain of Unknown Function (DUF1259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1529
LZS3_k127_2270458_6	234267.Acid_1153	6.11e-127	411.0	COG0774@1|root,COG0774@2|Bacteria,3Y40I@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
LZS3_k127_2270458_15	234267.Acid_3580	3.231e-44	163.0	COG0838@1|root,COG0838@2|Bacteria,3Y59B@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
LZS3_k127_2270458_28	1123226.KB899299_gene3388	1.192e-08	64.0	COG3861@1|root,COG3861@2|Bacteria,1V5RZ@1239|Firmicutes,4HHAU@91061|Bacilli,26SHD@186822|Paenibacillaceae	91061|Bacilli	S	Heat induced stress protein YflT	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,YflT
LZS3_k127_2270458_16	1205680.CAKO01000002_gene2312	2.964e-43	171.0	COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,2UC22@28211|Alphaproteobacteria,2JTWE@204441|Rhodospirillales	204441|Rhodospirillales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
LZS3_k127_2270458_14	136273.GY22_04940	5.576e-50	188.0	COG0596@1|root,COG0596@2|Bacteria,2IDI0@201174|Actinobacteria,1WABF@1268|Micrococcaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
LZS3_k127_2270458_17	234267.Acid_4914	2.642e-41	157.0	COG0531@1|root,COG0531@2|Bacteria,3Y3Z8@57723|Acidobacteria	2|Bacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
LZS3_k127_2283290_15	1121930.AQXG01000005_gene710	2.367e-12	70.0	COG2197@1|root,COG2197@2|Bacteria,4NN0B@976|Bacteroidetes,1IZ64@117747|Sphingobacteriia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_2283290_7	471854.Dfer_3350	1.09e-96	331.0	COG3964@1|root,COG3964@2|Bacteria,4NI4W@976|Bacteroidetes,47MS7@768503|Cytophagia	976|Bacteroidetes	S	PFAM amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_2283290_5	574087.Acear_1925	1.3e-108	366.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia	186801|Clostridia	EG	Gluconate	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
LZS3_k127_2283290_1	700598.Niako_3776	1.823e-158	512.0	COG0001@1|root,COG0001@2|Bacteria,4NK1U@976|Bacteroidetes,1IW3U@117747|Sphingobacteriia	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_2283290_6	886293.Sinac_2092	6.74e-97	338.0	28KEJ@1|root,2ZA0T@2|Bacteria,2J2GX@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2283290_8	272134.KB731324_gene4384	3.617e-73	258.0	COG3386@1|root,COG3386@2|Bacteria,1G2S8@1117|Cyanobacteria,1H7NZ@1150|Oscillatoriales	1117|Cyanobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
LZS3_k127_2283290_10	368407.Memar_1119	1.304e-50	195.0	COG1672@1|root,arCOG03172@2157|Archaea	2157|Archaea	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2283290_3	402777.KB235898_gene5099	4.364e-116	407.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2,TPR_1,TPR_8
LZS3_k127_2283290_0	234267.Acid_6681	3.958e-208	655.0	COG1271@1|root,COG1271@2|Bacteria,3Y44V@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
LZS3_k127_2283290_2	234267.Acid_6682	1.135e-151	493.0	COG1294@1|root,COG1294@2|Bacteria,3Y3UT@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome d ubiquinol oxidase, subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
LZS3_k127_2283290_9	234267.Acid_0319	3.921e-62	223.0	COG0705@1|root,COG0705@2|Bacteria,3Y4GU@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
LZS3_k127_2283290_4	234267.Acid_0320	2.987e-111	368.0	COG0235@1|root,COG0235@2|Bacteria,3Y4E0@57723|Acidobacteria	57723|Acidobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
LZS3_k127_2283290_11	880073.Calab_1623	1.74e-37	142.0	COG4577@1|root,COG4577@2|Bacteria,2NRBW@2323|unclassified Bacteria	2|Bacteria	CQ	COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	eutM	GO:0003674,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0031469,GO:0031471,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464	-	ko:K04027,ko:K04028	-	-	-	-	ko00000	-	-	-	BMC
LZS3_k127_2283290_12	234267.Acid_0322	2.326e-36	139.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028,ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
LZS3_k127_2283290_14	234267.Acid_0323	3.115e-24	104.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
LZS3_k127_2283290_13	234267.Acid_0324	1.136e-32	130.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	eutN	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
LZS3_k127_228510_4	525919.Apre_0042	6.603e-09	67.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,22GK1@1570339|Peptoniphilaceae	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
LZS3_k127_228510_0	234267.Acid_1620	5.237e-116	412.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,PEGA,Plug,TonB_dep_Rec
LZS3_k127_228510_3	234267.Acid_2587	4.714e-18	93.0	COG1595@1|root,COG1595@2|Bacteria,3Y87A@57723|Acidobacteria	57723|Acidobacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
LZS3_k127_228510_5	886293.Sinac_7031	6.446e-05	52.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS3_k127_228510_2	234267.Acid_1395	1.835e-22	108.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
LZS3_k127_2289673_11	1267533.KB906740_gene378	9.561e-08	53.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	MA20_40075	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
LZS3_k127_2289673_8	204669.Acid345_1119	4.336e-23	103.0	COG2823@1|root,COG2823@2|Bacteria,3Y8FT@57723|Acidobacteria,2JNE8@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS3_k127_2289673_4	1267533.KB906733_gene3080	2.998e-71	246.0	COG3861@1|root,COG3861@2|Bacteria,3Y5WZ@57723|Acidobacteria,2JM78@204432|Acidobacteriia	204432|Acidobacteriia	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS3_k127_2289673_9	204669.Acid345_2776	1.799e-19	94.0	COG1943@1|root,COG1943@2|Bacteria,3Y81S@57723|Acidobacteria,2JN69@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA binding domain with preference for A/T rich regions	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS3_k127_2289673_7	1380391.JIAS01000019_gene1108	2.859e-23	100.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,2JUNU@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
LZS3_k127_2289673_5	1121405.dsmv_3081	4.788e-51	184.0	2C8DW@1|root,32RKY@2|Bacteria,1MZUD@1224|Proteobacteria,432NJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function (DUF3597)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3597
LZS3_k127_2289673_3	76114.ebA4980	2.249e-78	268.0	COG5403@1|root,COG5403@2|Bacteria,1N0H4@1224|Proteobacteria,2W217@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
LZS3_k127_2289673_0	1121405.dsmv_3003	0.0	4115.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
LZS3_k127_2289673_6	204669.Acid345_1266	3.536e-40	158.0	COG2834@1|root,COG2834@2|Bacteria,3Y8R6@57723|Acidobacteria,2JNE5@204432|Acidobacteriia	204432|Acidobacteriia	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2289673_1	1267535.KB906767_gene3728	4.613e-201	644.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS3_k127_2289673_10	1267535.KB906767_gene2743	4.59e-19	99.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25,PG_binding_1
LZS3_k127_2289673_2	1267535.KB906767_gene3727	2.503e-100	338.0	COG2930@1|root,COG2930@2|Bacteria,3Y6Q0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
LZS3_k127_2292154_0	765911.Thivi_3037	1.302e-163	531.0	COG0471@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1WXUN@135613|Chromatiales	135613|Chromatiales	P	TrkA-C domain	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
LZS3_k127_2292154_3	234267.Acid_6633	1.157e-54	205.0	COG1493@1|root,COG1493@2|Bacteria,3Y4YI@57723|Acidobacteria	57723|Acidobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2292154_1	1340493.JNIF01000004_gene838	6.656e-96	322.0	COG0684@1|root,COG0684@2|Bacteria,3Y7HG@57723|Acidobacteria	57723|Acidobacteria	M	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
LZS3_k127_2292154_6	1267535.KB906767_gene223	4.923e-19	94.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_2292154_5	1397527.Q670_04325	3.99e-19	93.0	2DR7K@1|root,33AJE@2|Bacteria,1NEYA@1224|Proteobacteria	1224|Proteobacteria	S	Cysteine-rich CPCC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPCC
LZS3_k127_2292154_11	1114964.L485_04575	9.557e-05	54.0	COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria,2K09X@204457|Sphingomonadales	204457|Sphingomonadales	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
LZS3_k127_2292154_8	234267.Acid_1140	1.532e-08	59.0	COG4980@1|root,COG4980@2|Bacteria,3Y8W2@57723|Acidobacteria	57723|Acidobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS3_k127_2292154_2	56780.SYN_02762	2.357e-72	260.0	COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
LZS3_k127_2292154_12	1163671.JAGI01000002_gene2396	0.0007961	48.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,36HY7@31979|Clostridiaceae	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_2301507_21	1120973.AQXL01000104_gene2585	3.827e-12	70.0	COG5285@1|root,COG5285@2|Bacteria,1UZS3@1239|Firmicutes,4HA3M@91061|Bacilli	91061|Bacilli	Q	Phytanoyl-CoA dioxygenase (PhyH)	ectD	-	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
LZS3_k127_2301507_10	1042375.AFPL01000040_gene2755	1.614e-50	185.0	COG1917@1|root,COG1917@2|Bacteria,1RDGQ@1224|Proteobacteria,1S41A@1236|Gammaproteobacteria,4674S@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
LZS3_k127_2301507_0	644282.Deba_1357	1.387e-183	587.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42N1V@68525|delta/epsilon subdivisions,2WKME@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_2301507_11	1122212.AULO01000011_gene520	6.548e-47	174.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria,1XJYH@135619|Oceanospirillales	135619|Oceanospirillales	K	L-2,4-diaminobutyric acid acetyltransferase	ectA	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
LZS3_k127_2301507_12	1232410.KI421417_gene2728	1.115e-41	160.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,43AC3@68525|delta/epsilon subdivisions,2X5RZ@28221|Deltaproteobacteria,43UX1@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
LZS3_k127_2301507_8	909663.KI867150_gene69	9.909e-62	220.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2301507_18	909663.KI867150_gene1862	3.609e-16	79.0	COG1917@1|root,COG1917@2|Bacteria,1RJX2@1224|Proteobacteria,42TVK@68525|delta/epsilon subdivisions,2WQ2T@28221|Deltaproteobacteria,2MQJ4@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_2301507_22	304371.MCP_1478	2.358e-05	49.0	COG1917@1|root,arCOG03004@2157|Archaea,2XYUR@28890|Euryarchaeota,2NB2H@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_2301507_14	314264.ROS217_02295	1.835e-25	111.0	COG2820@1|root,COG2820@2|Bacteria,1PN5U@1224|Proteobacteria,2TTHM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
LZS3_k127_2301507_4	768671.ThimaDRAFT_3236	1.239e-81	283.0	COG1215@1|root,COG1215@2|Bacteria,1QUG1@1224|Proteobacteria,1RZH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_2301507_9	1121405.dsmv_3670	3.605e-61	227.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,42Q95@68525|delta/epsilon subdivisions,2WKM2@28221|Deltaproteobacteria,2MIMV@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_5,Phage_integrase
LZS3_k127_2301507_20	991905.SL003B_1681	4.535e-14	79.0	COG3740@1|root,COG3740@2|Bacteria,1NQP7@1224|Proteobacteria,2UQRP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Caudovirus prohead serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78
LZS3_k127_2301507_15	240292.Ava_3256	1.222e-24	114.0	2E6E7@1|root,3311P@2|Bacteria,1GDDS@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2301507_19	927677.ALVU02000001_gene2140	1.438e-15	83.0	COG1715@1|root,COG1715@2|Bacteria	2|Bacteria	V	Restriction endonuclease	-	-	2.1.1.72	ko:K00571,ko:K07448	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5,Mrr_N,Mrr_cat
LZS3_k127_2301507_17	927677.ALVU02000001_gene2139	1.438e-16	86.0	2CI7Y@1|root,3309I@2|Bacteria,1G995@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2301507_1	234267.Acid_7329	2.867e-137	445.0	COG0535@1|root,COG0535@2|Bacteria,3Y2KT@57723|Acidobacteria	57723|Acidobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS3_k127_2301507_7	234267.Acid_3322	2.574e-66	234.0	COG2846@1|root,COG2846@2|Bacteria,3Y4SU@57723|Acidobacteria	57723|Acidobacteria	C	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
LZS3_k127_2301507_13	945713.IALB_1656	1.669e-27	119.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
LZS3_k127_2301507_3	1267535.KB906767_gene3880	1.427e-83	297.0	arCOG02075@1|root,33AGA@2|Bacteria,3Y7D5@57723|Acidobacteria	57723|Acidobacteria	S	NnrS protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrS
LZS3_k127_2301507_5	234267.Acid_7867	9.008e-71	251.0	COG0664@1|root,COG0664@2|Bacteria,3Y4WU@57723|Acidobacteria	57723|Acidobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_2301507_6	247490.KSU1_B0185	9.932e-69	256.0	COG2846@1|root,COG2846@2|Bacteria,2J23U@203682|Planctomycetes	203682|Planctomycetes	D	NnrS protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,NnrS
LZS3_k127_2301507_2	234267.Acid_0187	1.125e-87	304.0	COG3637@1|root,COG3637@2|Bacteria,3Y783@57723|Acidobacteria	57723|Acidobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
LZS3_k127_2320860_8	56780.SYN_03092	1.633e-21	98.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42S30@68525|delta/epsilon subdivisions,2WQ5S@28221|Deltaproteobacteria,2MRTS@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
LZS3_k127_2320860_3	1267535.KB906767_gene5141	1.151e-119	410.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y3FE@57723|Acidobacteria	57723|Acidobacteria	KU	WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
LZS3_k127_2320860_0	1267535.KB906767_gene4837	0.0	1238.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_2320860_5	1267535.KB906767_gene4839	4.376e-79	276.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene4839|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2320860_7	1267535.KB906767_gene53	1.357e-32	144.0	COG0457@1|root,COG0457@2|Bacteria,3Y7EV@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
LZS3_k127_2320860_4	1267535.KB906767_gene53	1.406e-87	308.0	COG0457@1|root,COG0457@2|Bacteria,3Y7EV@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
LZS3_k127_2320860_1	1267535.KB906767_gene3809	1.249e-251	797.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3809|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2320860_2	1267535.KB906767_gene3810	5.664e-205	651.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene3810|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2320860_6	1267535.KB906767_gene4836	2.991e-50	183.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene4836|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_233481_1	1340493.JNIF01000003_gene1856	1.161e-185	591.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
LZS3_k127_233481_6	1340493.JNIF01000003_gene3802	5.494e-65	227.0	COG0328@1|root,COG0328@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
LZS3_k127_233481_2	234267.Acid_6679	4.022e-148	475.0	COG0042@1|root,COG0042@2|Bacteria,3Y3XE@57723|Acidobacteria	57723|Acidobacteria	J	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Dus
LZS3_k127_233481_7	1340493.JNIF01000004_gene559	4.005e-62	218.0	COG2193@1|root,COG2193@2|Bacteria,3Y56Z@57723|Acidobacteria	57723|Acidobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
LZS3_k127_233481_4	1379270.AUXF01000001_gene1895	1.245e-107	359.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS3_k127_233481_0	1267535.KB906767_gene3340	3.799e-217	680.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria,2JIPN@204432|Acidobacteriia	204432|Acidobacteriia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
LZS3_k127_233481_5	234267.Acid_4403	5.032e-81	290.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	pglZ	-	-	-	-	-	-	-	-	-	-	-	PglZ,Phosphodiest
LZS3_k127_233481_3	234267.Acid_4402	1.799e-129	427.0	COG0167@1|root,COG0167@2|Bacteria,3Y2K1@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS3_k127_233481_8	397278.JOJN01000001_gene2904	2.934e-45	172.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4DNET@85009|Propionibacteriales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
LZS3_k127_233481_9	278963.ATWD01000001_gene3794	1.218e-24	108.0	COG1950@1|root,COG1950@2|Bacteria,3Y5FT@57723|Acidobacteria,2JJY4@204432|Acidobacteriia	204432|Acidobacteriia	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
LZS3_k127_2348837_0	1122605.KB893637_gene3269	8.026e-207	677.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
LZS3_k127_2348837_3	1123277.KB893174_gene5952	3.532e-153	499.0	COG3540@1|root,COG3540@2|Bacteria,4PIVI@976|Bacteroidetes,47SNE@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
LZS3_k127_2348837_2	1123277.KB893174_gene5952	1.532e-156	508.0	COG3540@1|root,COG3540@2|Bacteria,4PIVI@976|Bacteroidetes,47SNE@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
LZS3_k127_2348837_4	401053.AciPR4_1228	2.822e-71	256.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	-	-	2.3.1.209,2.7.7.23,2.7.7.83	ko:K00972,ko:K21379	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
LZS3_k127_2348837_1	234267.Acid_4756	3.957e-192	613.0	COG0013@1|root,COG0013@2|Bacteria,3Y359@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS3_k127_2354046_23	639030.JHVA01000001_gene2666	4.675e-06	49.0	COG1502@1|root,COG1502@2|Bacteria,3Y2GD@57723|Acidobacteria,2JKZ7@204432|Acidobacteriia	204432|Acidobacteriia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS3_k127_2354046_16	1196322.A370_02909	1.046e-32	130.0	COG4249@1|root,COG4249@2|Bacteria,1UA57@1239|Firmicutes,24CYB@186801|Clostridia,36PAI@31979|Clostridiaceae	186801|Clostridia	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
LZS3_k127_2354046_19	641524.ADICYQ_0168	8.44e-21	98.0	COG5476@1|root,COG5476@2|Bacteria,4NKYT@976|Bacteroidetes,47XQY@768503|Cytophagia	976|Bacteroidetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
LZS3_k127_2354046_17	1250006.JHZZ01000001_gene550	2.302e-24	121.0	COG1672@1|root,COG1672@2|Bacteria,4PB0S@976|Bacteroidetes,1IMNC@117743|Flavobacteriia,3VXEN@52959|Polaribacter	976|Bacteroidetes	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2354046_11	518766.Rmar_0141	4.957e-58	213.0	COG0668@1|root,COG0668@2|Bacteria,4NMNE@976|Bacteroidetes	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS3_k127_2354046_24	1042375.AFPL01000010_gene457	0.0004452	53.0	COG1196@1|root,COG1196@2|Bacteria,1R4SX@1224|Proteobacteria,1RVI9@1236|Gammaproteobacteria,466HF@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Domain of Unknown Function (DUF349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF349
LZS3_k127_2354046_21	278963.ATWD01000001_gene3174	1.739e-11	78.0	2EKZZ@1|root,33EPG@2|Bacteria,3Y5U9@57723|Acidobacteria,2JKFN@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Lipase_GDSL_2
LZS3_k127_2354046_22	1343740.M271_23420	1.205e-07	65.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
LZS3_k127_2354046_20	1267535.KB906767_gene4996	5.631e-18	99.0	2EKZZ@1|root,33EPG@2|Bacteria,3Y5U9@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Lipase_GDSL_2
LZS3_k127_2354046_15	497964.CfE428DRAFT_4524	3.195e-37	144.0	COG0454@1|root,COG0456@2|Bacteria,46VJ5@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
LZS3_k127_2354046_0	234267.Acid_6443	0.0	1266.0	COG0178@1|root,COG0178@2|Bacteria,3Y3PA@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS3_k127_2354046_5	69395.JQLZ01000005_gene3819	4.711e-140	456.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_2354046_14	1499967.BAYZ01000014_gene6411	1.195e-37	154.0	COG0407@1|root,COG0407@2|Bacteria,2NPIC@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
LZS3_k127_2354046_10	1499967.BAYZ01000101_gene3592	2.934e-73	261.0	COG1816@1|root,COG1816@2|Bacteria	2|Bacteria	F	deaminase activity	add	-	3.5.4.2,3.5.4.4	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01244,R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
LZS3_k127_2354046_13	309803.CTN_0650	2.422e-38	151.0	COG0801@1|root,COG0801@2|Bacteria,2GDA7@200918|Thermotogae	200918|Thermotogae	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0041	HPPK
LZS3_k127_2354046_18	1121422.AUMW01000011_gene110	6.469e-22	102.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,24MN5@186801|Clostridia,262E7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
LZS3_k127_2354046_8	926560.KE387023_gene2862	2.073e-83	286.0	COG0294@1|root,COG0294@2|Bacteria,1WJ2K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
LZS3_k127_2354046_3	641524.ADICYQ_0168	1.315e-214	677.0	COG5476@1|root,COG5476@2|Bacteria,4NKYT@976|Bacteroidetes,47XQY@768503|Cytophagia	976|Bacteroidetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
LZS3_k127_2354046_4	1267535.KB906767_gene186	5.605e-161	522.0	COG2721@1|root,COG2721@2|Bacteria,3Y6SX@57723|Acidobacteria	57723|Acidobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
LZS3_k127_2354046_12	1267005.KB911259_gene3953	1.756e-39	158.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
LZS3_k127_2354046_9	1267535.KB906767_gene2132	4.449e-80	284.0	COG5616@1|root,COG5616@2|Bacteria,3Y9AR@57723|Acidobacteria,2JP78@204432|Acidobacteriia	204432|Acidobacteriia	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2354046_1	1267535.KB906767_gene5042	0.0	1084.0	COG1629@1|root,COG1629@2|Bacteria,3Y2ZC@57723|Acidobacteria,2JK8R@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_2354046_2	1267535.KB906767_gene1802	5.321e-240	752.0	COG2225@1|root,COG2225@2|Bacteria,3Y4MK@57723|Acidobacteria,2JKQY@204432|Acidobacteriia	204432|Acidobacteriia	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
LZS3_k127_2354046_6	264732.Moth_1590	1.824e-106	364.0	COG2271@1|root,COG2271@2|Bacteria,1V0WU@1239|Firmicutes,25E6S@186801|Clostridia,42GB3@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
LZS3_k127_2354046_7	383372.Rcas_0698	2.867e-103	347.0	COG1893@1|root,COG1893@2|Bacteria,2GAI6@200795|Chloroflexi,376A7@32061|Chloroflexia	32061|Chloroflexia	H	2-dehydropantoate 2-reductase	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS3_k127_2374896_3	204669.Acid345_1253	1.799e-20	94.0	COG0346@1|root,COG0346@2|Bacteria,3Y5V6@57723|Acidobacteria,2JNV6@204432|Acidobacteriia	204432|Acidobacteriia	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2374896_2	682795.AciX8_1019	1.737e-23	108.0	COG1664@1|root,COG1664@2|Bacteria,3Y49V@57723|Acidobacteria,2JJ4E@204432|Acidobacteriia	204432|Acidobacteriia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS3_k127_2374896_0	204669.Acid345_3543	1.054e-194	620.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR
LZS3_k127_2374896_1	926560.KE387023_gene2039	6.856e-102	344.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_2376388_1	1048983.EL17_09250	1.383e-123	409.0	COG1228@1|root,COG1228@2|Bacteria,4NGGD@976|Bacteroidetes,47R4K@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,SnoaL_2
LZS3_k127_2376388_2	886293.Sinac_1894	5.719e-95	324.0	29CVJ@1|root,2ZZTQ@2|Bacteria,2IZ72@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2376388_8	1197130.BAFM01000021_gene2849	1.625e-07	61.0	COG0662@1|root,arCOG03003@2157|Archaea,2XX6B@28890|Euryarchaeota,23WEI@183963|Halobacteria	183963|Halobacteria	G	COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_2376388_0	1379698.RBG1_1C00001G0607	1.313e-184	602.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS3_k127_2376388_3	344747.PM8797T_25126	8.665e-63	233.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS3_k127_2376388_6	391625.PPSIR1_16480	2.495e-24	105.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria,2Z0RF@29|Myxococcales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
LZS3_k127_2376388_7	335659.S23_40110	3.166e-09	59.0	2EGMY@1|root,33AE3@2|Bacteria,1NGG3@1224|Proteobacteria,2UY3I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2376388_4	234267.Acid_7029	7.382e-53	197.0	COG1295@1|root,COG1295@2|Bacteria,3Y3AJ@57723|Acidobacteria	57723|Acidobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS3_k127_2376388_5	234267.Acid_4060	3.577e-30	124.0	COG4102@1|root,COG4102@2|Bacteria,3Y6RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_2386998_12	177437.HRM2_22780	3.274e-24	105.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria	1224|Proteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_3
LZS3_k127_2386998_13	156889.Mmc1_2624	7.014e-22	101.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_2386998_2	1340493.JNIF01000003_gene4303	4.415e-118	390.0	COG3616@1|root,COG3616@2|Bacteria,3Y7EX@57723|Acidobacteria	57723|Acidobacteria	E	Putative serine dehydratase domain	-	-	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
LZS3_k127_2386998_5	1126627.BAWE01000002_gene699	1.859e-81	286.0	COG3964@1|root,COG3964@2|Bacteria,1MVC7@1224|Proteobacteria,2TSUD@28211|Alphaproteobacteria,3JSBJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase family	MA20_40145	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_2386998_6	1071073.KI530549_gene3504	8.891e-80	284.0	COG0591@1|root,COG0591@2|Bacteria,1TQCK@1239|Firmicutes,4HB5K@91061|Bacilli	91061|Bacilli	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS3_k127_2386998_9	234267.Acid_7150	7.461e-39	158.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,3Y3WP@57723|Acidobacteria	57723|Acidobacteria	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
LZS3_k127_2386998_8	515635.Dtur_0404	2.683e-52	196.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase
LZS3_k127_2386998_7	530564.Psta_4263	5.464e-54	209.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	psrP1	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHU_C,GSDH,Malectin
LZS3_k127_2386998_11	205918.Psyr_3156	3.268e-37	153.0	COG0583@1|root,COG0583@2|Bacteria,1NSNV@1224|Proteobacteria,1RPNG@1236|Gammaproteobacteria,1Z852@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	cysL_1	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS3_k127_2386998_1	234267.Acid_0194	7.064e-160	542.0	COG1629@1|root,COG4771@2|Bacteria,3Y7GJ@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_2386998_15	616991.JPOO01000001_gene2853	9.816e-14	83.0	COG4409@1|root,COG4409@2|Bacteria,4PAPR@976|Bacteroidetes,1IF7B@117743|Flavobacteriia,23HKK@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
LZS3_k127_2386998_16	1267535.KB906767_gene5472	9.04e-08	54.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_2386998_4	1267535.KB906767_gene5472	4.466e-88	297.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_2386998_17	1313301.AUGC01000020_gene692	2.59e-07	55.0	COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes	976|Bacteroidetes	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_2386998_3	886293.Sinac_6966	8.622e-112	372.0	COG0726@1|root,COG0726@2|Bacteria,2IXYV@203682|Planctomycetes	203682|Planctomycetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS3_k127_2386998_0	234267.Acid_5704	3.276e-254	791.0	COG0119@1|root,COG0119@2|Bacteria,3Y2WT@57723|Acidobacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10690,iYO844.BSU28280	HMGL-like,LeuA_dimer
LZS3_k127_2386998_14	156889.Mmc1_2624	4.921e-16	81.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_2388017_2	1123070.KB899262_gene1677	9.987e-30	136.0	COG0412@1|root,COG1404@1|root,COG2755@1|root,COG3317@1|root,COG0412@2|Bacteria,COG1404@2|Bacteria,COG2755@2|Bacteria,COG3317@2|Bacteria,46WFV@74201|Verrucomicrobia,2IUW0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
LZS3_k127_2388017_0	1123248.KB893318_gene4130	3.361e-314	1008.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1IUSY@117747|Sphingobacteriia	976|Bacteroidetes	G	family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
LZS3_k127_2388017_1	1142394.PSMK_05960	8.169e-49	189.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,BNR_4
LZS3_k127_2450725_0	1232410.KI421424_gene1799	3.172e-165	535.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,43SUE@69541|Desulfuromonadales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
LZS3_k127_2450725_1	234267.Acid_1065	8.361e-156	499.0	COG2876@1|root,COG2876@2|Bacteria,3Y64W@57723|Acidobacteria	57723|Acidobacteria	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS3_k127_2450725_2	234267.Acid_1440	1.797e-75	267.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2,RNA_lig_T4_1
LZS3_k127_2450725_3	1108045.GORHZ_084_00430	2.162e-23	101.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4GEP0@85026|Gordoniaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
LZS3_k127_2458523_6	886293.Sinac_4980	4.115e-82	285.0	COG3266@1|root,COG3266@2|Bacteria,2IZFW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
LZS3_k127_2458523_13	1305735.JAFT01000005_gene2489	6.8e-07	58.0	COG0715@1|root,COG0715@2|Bacteria,1NF3S@1224|Proteobacteria,2TREQ@28211|Alphaproteobacteria,2PDFM@252301|Oceanicola	28211|Alphaproteobacteria	P	NMT1-like family	MA20_40210	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
LZS3_k127_2458523_5	497964.CfE428DRAFT_6367	2.382e-96	323.0	COG0426@1|root,COG0426@2|Bacteria,46UCH@74201|Verrucomicrobia	74201|Verrucomicrobia	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2458523_0	234267.Acid_6445	2.818e-300	946.0	COG1615@1|root,COG1615@2|Bacteria,3Y6XA@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
LZS3_k127_2458523_1	234267.Acid_5513	3.27e-182	581.0	COG0044@1|root,COG0044@2|Bacteria,3Y34R@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS3_k127_2458523_3	234267.Acid_5512	3.016e-141	455.0	COG0540@1|root,COG0540@2|Bacteria,3Y3KK@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS3_k127_2458523_11	1379698.RBG1_1C00001G0607	9.9e-12	72.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS3_k127_2458523_9	1303518.CCALI_02277	4.908e-12	77.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	ulaG	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
LZS3_k127_2458523_7	234267.Acid_0770	3.888e-63	226.0	2F1JK@1|root,33UK0@2|Bacteria,3Y7KY@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2458523_4	1267535.KB906767_gene4237	6.119e-126	413.0	COG0451@1|root,COG0451@2|Bacteria,3Y6G4@57723|Acidobacteria,2JM4D@204432|Acidobacteriia	204432|Acidobacteriia	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_2458523_2	717605.Theco_1235	5.257e-142	459.0	COG0329@1|root,COG0329@2|Bacteria,1UNIU@1239|Firmicutes,4HAWE@91061|Bacilli,26TG8@186822|Paenibacillaceae	91061|Bacilli	EM	dihydrodipicolinate synthetase	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
LZS3_k127_2458523_8	319003.Bra1253DRAFT_07766	4.644e-59	216.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2U66N@28211|Alphaproteobacteria,3JYD3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
LZS3_k127_2459649_14	243231.GSU2816	3.23e-28	117.0	COG2204@1|root,COG4191@1|root,COG5000@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,43TMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS3_k127_2459649_11	1267535.KB906767_gene3496	7.03e-52	188.0	COG1943@1|root,COG1943@2|Bacteria,3Y84T@57723|Acidobacteria	57723|Acidobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS3_k127_2459649_3	234267.Acid_5378	7.213e-189	596.0	COG0436@1|root,COG0436@2|Bacteria,3Y6EJ@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_2459649_10	234267.Acid_7450	2.729e-63	227.0	COG1706@1|root,COG1706@2|Bacteria,3Y2UQ@57723|Acidobacteria	57723|Acidobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
LZS3_k127_2459649_19	234267.Acid_7464	5.857e-12	70.0	COG1377@1|root,COG1377@2|Bacteria,3Y4JK@57723|Acidobacteria	57723|Acidobacteria	NU	FlhB HrpN YscU SpaS Family	-	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
LZS3_k127_2459649_22	582744.Msip34_0791	2.356e-07	53.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria,2KMIP@206350|Nitrosomonadales	206350|Nitrosomonadales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
LZS3_k127_2459649_24	243231.GSU0426	1.888e-05	50.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2WJIQ@28221|Deltaproteobacteria,43UG3@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
LZS3_k127_2459649_17	234267.Acid_7464	3.462e-13	72.0	COG1377@1|root,COG1377@2|Bacteria,3Y4JK@57723|Acidobacteria	57723|Acidobacteria	NU	FlhB HrpN YscU SpaS Family	-	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
LZS3_k127_2459649_8	1267535.KB906767_gene3924	5.3e-84	286.0	COG1298@1|root,COG1298@2|Bacteria,3Y3YR@57723|Acidobacteria,2JIRD@204432|Acidobacteriia	204432|Acidobacteriia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
LZS3_k127_2459649_21	1321781.HMPREF1985_02064	9.595e-10	64.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H2XV@909932|Negativicutes	909932|Negativicutes	N	Flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
LZS3_k127_2459649_7	1340493.JNIF01000003_gene3261	1.16e-90	306.0	COG1191@1|root,COG1191@2|Bacteria,3Y4Q5@57723|Acidobacteria	57723|Acidobacteria	K	TIGRFAM RNA polymerase sigma factor, FliA WhiG family	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_2459649_18	1267535.KB906767_gene1749	1.977e-12	67.0	COG1868@1|root,COG1868@2|Bacteria,3Y49R@57723|Acidobacteria,2JJ4N@204432|Acidobacteriia	204432|Acidobacteriia	N	flagellar motor switch protein FliM	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
LZS3_k127_2459649_23	234267.Acid_5365	2.754e-06	57.0	COG1868@1|root,COG1868@2|Bacteria,3Y49R@57723|Acidobacteria	57723|Acidobacteria	N	flagellar motor switch protein FliM	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
LZS3_k127_2459649_1	869210.Marky_0378	2.357e-209	665.0	COG1509@1|root,COG1509@2|Bacteria,1WKKI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM KamA family protein	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C,Radical_SAM
LZS3_k127_2459649_6	234267.Acid_3047	2.044e-111	372.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
LZS3_k127_2459649_20	1210884.HG799462_gene8125	5.03e-10	66.0	2EH81@1|root,33AZW@2|Bacteria,2J1J2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2459649_9	1340493.JNIF01000003_gene2370	3.151e-64	230.0	COG3597@1|root,COG3597@2|Bacteria,3Y7Z9@57723|Acidobacteria	57723|Acidobacteria	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2459649_5	1340493.JNIF01000004_gene702	1.562e-154	505.0	COG0728@1|root,COG0728@2|Bacteria,3Y31G@57723|Acidobacteria	57723|Acidobacteria	S	virulence factor MVIN family protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
LZS3_k127_2459649_4	266117.Rxyl_1685	1.532e-159	518.0	COG1070@1|root,COG1070@2|Bacteria,2GISK@201174|Actinobacteria,4CPQB@84995|Rubrobacteria	84995|Rubrobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
LZS3_k127_2459649_2	234267.Acid_0738	2.071e-193	648.0	COG5316@1|root,COG5316@2|Bacteria,3Y46P@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
LZS3_k127_2459649_0	1340493.JNIF01000003_gene4764	4.434e-252	796.0	arCOG10801@1|root,2Z9IC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2459649_13	247490.KSU1_A0074	6.616e-32	135.0	COG0664@1|root,COG0664@2|Bacteria,2J0N9@203682|Planctomycetes	203682|Planctomycetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
LZS3_k127_2459649_12	1267535.KB906767_gene3861	1.939e-51	188.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
LZS3_k127_2459649_16	1123240.ATVO01000006_gene1400	2.006e-13	79.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TUI2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	L-aminopeptidase D-esterase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
LZS3_k127_2466671_15	1267535.KB906767_gene110	1.937e-18	89.0	2DF3Q@1|root,2ZQCR@2|Bacteria,3Y8YJ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2466671_5	1267535.KB906767_gene3460	1.165e-98	330.0	COG1721@1|root,COG1721@2|Bacteria,3Y6DV@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS3_k127_2466671_3	234267.Acid_5744	7.571e-117	402.0	COG2304@1|root,COG2304@2|Bacteria,3Y6TM@57723|Acidobacteria	57723|Acidobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
LZS3_k127_2466671_0	234267.Acid_5743	4.467e-267	846.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,3Y6PH@57723|Acidobacteria	57723|Acidobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA
LZS3_k127_2466671_13	240015.ACP_0992	1.072e-29	124.0	COG0457@1|root,COG0457@2|Bacteria	240015.ACP_0992|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2466671_17	1267535.KB906767_gene4783	1.668e-05	51.0	293BI@1|root,2ZQU6@2|Bacteria,3Y92V@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2466671_8	1267535.KB906767_gene4784	2.635e-69	239.0	COG1595@1|root,COG1595@2|Bacteria,3Y6DK@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_2466671_2	1267535.KB906767_gene218	1.826e-152	494.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2466671_11	234267.Acid_0789	3.789e-53	205.0	COG3595@1|root,COG3595@2|Bacteria,3Y3K3@57723|Acidobacteria	57723|Acidobacteria	C	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
LZS3_k127_2466671_12	234267.Acid_0791	2.36e-39	158.0	2DMGW@1|root,32REM@2|Bacteria,3Y4XX@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
LZS3_k127_2466671_14	234267.Acid_0792	2.628e-21	103.0	COG5662@1|root,COG5662@2|Bacteria,3Y4S0@57723|Acidobacteria	57723|Acidobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS3_k127_2466671_10	234267.Acid_0793	1.486e-62	222.0	COG1595@1|root,COG1595@2|Bacteria,3Y4HK@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_2466671_7	234267.Acid_0794	1.002e-72	258.0	COG0392@1|root,COG0392@2|Bacteria,3Y3SG@57723|Acidobacteria	57723|Acidobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS3_k127_2466671_9	234267.Acid_0795	3.278e-67	233.0	COG1327@1|root,COG1327@2|Bacteria,3Y4GA@57723|Acidobacteria	57723|Acidobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
LZS3_k127_2466671_1	1267535.KB906767_gene1045	1.238e-184	593.0	COG0568@1|root,COG0568@2|Bacteria,3Y2XG@57723|Acidobacteria,2JHX1@204432|Acidobacteriia	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_2466671_6	234267.Acid_1035	4.863e-78	268.0	COG0463@1|root,COG0463@2|Bacteria,3Y982@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_2490294_12	926569.ANT_24800	4.961e-12	69.0	COG3303@1|root,COG3303@2|Bacteria,2GBNG@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
LZS3_k127_2490294_9	234267.Acid_5333	7.371e-104	358.0	COG0154@1|root,COG0154@2|Bacteria,3Y6E5@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS3_k127_2490294_3	1340493.JNIF01000004_gene505	2.318e-129	424.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
LZS3_k127_2490294_10	1128421.JAGA01000003_gene2807	4.938e-42	159.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	-
LZS3_k127_2490294_4	69395.JQLZ01000005_gene3818	3.836e-127	420.0	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	-	-	-	ko:K03535	-	-	-	-	ko00000,ko02000	2.A.1.14.1	-	-	MFS_1
LZS3_k127_2490294_5	682795.AciX8_1155	6.743e-113	383.0	COG0745@1|root,COG0745@2|Bacteria,3Y2I8@57723|Acidobacteria,2JMD7@204432|Acidobacteriia	204432|Acidobacteriia	KT	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Malectin
LZS3_k127_2490294_1	1267535.KB906767_gene1639	2.045e-203	672.0	COG4775@1|root,COG4775@2|Bacteria,3Y9FK@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_2490294_2	1267535.KB906767_gene4930	6.592e-134	436.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS3_k127_2490294_7	234267.Acid_4467	1.841e-111	374.0	COG1363@1|root,COG1363@2|Bacteria,3Y2Y3@57723|Acidobacteria	57723|Acidobacteria	G	PFAM peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
LZS3_k127_2490294_11	351160.RCIX1292	1.539e-19	92.0	COG1695@1|root,arCOG00001@2157|Archaea	2157|Archaea	K	Transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
LZS3_k127_2490294_6	234267.Acid_2633	3.85e-112	381.0	COG1957@1|root,COG1957@2|Bacteria,3Y6U8@57723|Acidobacteria	57723|Acidobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
LZS3_k127_2490294_8	1303518.CCALI_02067	2.336e-109	368.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7
LZS3_k127_2490294_0	1267534.KB906754_gene3673	4.795e-246	777.0	28HBM@1|root,2Z7NK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2495280_4	1121403.AUCV01000003_gene1689	1.398e-121	403.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MHSV@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
LZS3_k127_2495280_3	1340493.JNIF01000004_gene280	7.258e-140	458.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC4_WD40,PD40,PSCyt1,WD40
LZS3_k127_2495280_2	1340493.JNIF01000004_gene279	8.147e-143	482.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TIR_2,WD40
LZS3_k127_2495280_1	1340493.JNIF01000004_gene278	2.149e-291	915.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PD40,PSCyt1,PSCyt2,PSD1,WD40
LZS3_k127_2495280_9	234267.Acid_5130	7.533e-85	290.0	COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
LZS3_k127_2495280_5	1267535.KB906767_gene5475	2.256e-121	395.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MA@57723|Acidobacteria,2JI5Q@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
LZS3_k127_2495280_12	1210884.HG799462_gene8541	5.921e-46	186.0	COG1262@1|root,COG1262@2|Bacteria,2IXQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FGE-sulfatase,TPR_11
LZS3_k127_2495280_19	234267.Acid_1014	1.388e-12	78.0	2FHG9@1|root,349AB@2|Bacteria,3Y8GZ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2495280_0	234267.Acid_6470	0.0	1069.0	COG4775@1|root,COG4775@2|Bacteria,3Y2Q9@57723|Acidobacteria	57723|Acidobacteria	M	Surface antigen variable number	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS3_k127_2495280_13	1382359.JIAL01000001_gene806	4.201e-26	115.0	COG2825@1|root,COG2825@2|Bacteria,3Y4WC@57723|Acidobacteria,2JJHF@204432|Acidobacteriia	204432|Acidobacteriia	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
LZS3_k127_2495280_8	391589.RGAI101_2339	9.953e-96	333.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_2495280_14	234267.Acid_3193	3.048e-24	111.0	COG2199@1|root,COG3706@2|Bacteria,3Y5QC@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_2495280_10	1267535.KB906767_gene2255	5.758e-57	203.0	COG1666@1|root,COG1666@2|Bacteria,3Y4I3@57723|Acidobacteria,2JJ8P@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
LZS3_k127_2495280_11	234267.Acid_3195	1.607e-56	208.0	COG2945@1|root,COG2945@2|Bacteria,3Y35I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
LZS3_k127_2495280_15	204669.Acid345_2776	6.601e-24	109.0	COG1943@1|root,COG1943@2|Bacteria,3Y81S@57723|Acidobacteria,2JN69@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA binding domain with preference for A/T rich regions	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS3_k127_2495280_20	537970.HCAN_0138	4.835e-05	51.0	2ES7M@1|root,33JSC@2|Bacteria,1NN1J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2495280_6	671143.DAMO_1295	5.903e-110	360.0	COG4422@1|root,COG4422@2|Bacteria	2|Bacteria	F	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
LZS3_k127_2495280_7	926569.ANT_23830	1.258e-107	360.0	COG4422@1|root,COG4422@2|Bacteria,2G8KX@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2495280_17	1121286.AUMT01000003_gene2121	1.541e-13	81.0	2AKU0@1|root,31BM2@2|Bacteria,4PIPJ@976|Bacteroidetes,1IKZ3@117743|Flavobacteriia,3ZT9X@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2495280_16	879212.DespoDRAFT_03732	3.897e-17	87.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria,2MJPT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS3_k127_2495280_18	344747.PM8797T_30581	7.072e-13	76.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4433,MR_MLE_C
LZS3_k127_252104_3	344747.PM8797T_30581	8.692e-118	394.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4433,MR_MLE_C
LZS3_k127_252104_11	1382359.JIAL01000001_gene1913	6.042e-12	76.0	COG1714@1|root,COG1714@2|Bacteria,3Y5I9@57723|Acidobacteria,2JJVV@204432|Acidobacteriia	204432|Acidobacteriia	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
LZS3_k127_252104_6	234267.Acid_3780	1.358e-51	191.0	COG1496@1|root,COG1496@2|Bacteria,3Y3J1@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
LZS3_k127_252104_4	1267535.KB906767_gene3324	1.467e-89	310.0	COG0805@1|root,COG0805@2|Bacteria,3Y3UC@57723|Acidobacteria,2JISU@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
LZS3_k127_252104_8	1340493.JNIF01000003_gene2257	5.808e-27	115.0	COG1826@1|root,COG1826@2|Bacteria,3Y5TY@57723|Acidobacteria	57723|Acidobacteria	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
LZS3_k127_252104_0	234267.Acid_7728	6.218e-173	552.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_252104_5	234267.Acid_6669	3.042e-64	229.0	COG2890@1|root,COG2890@2|Bacteria,3Y4KU@57723|Acidobacteria	57723|Acidobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
LZS3_k127_252104_1	234267.Acid_6670	5.392e-151	499.0	COG0216@1|root,COG0216@2|Bacteria,3Y2N9@57723|Acidobacteria	57723|Acidobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS3_k127_252104_2	234267.Acid_6671	4.034e-122	401.0	COG3872@1|root,COG3872@2|Bacteria,3Y66K@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
LZS3_k127_252104_7	234267.Acid_6507	4.977e-38	151.0	COG2834@1|root,COG2834@2|Bacteria,3Y51N@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA,LolA_like
LZS3_k127_252104_10	640081.Dsui_1657	1.3e-13	84.0	COG3659@1|root,COG3659@2|Bacteria,1Q8C7@1224|Proteobacteria,2VJFC@28216|Betaproteobacteria,2KURR@206389|Rhodocyclales	206389|Rhodocyclales	M	Carbohydrate-selective porin, OprB family	-	-	-	-	-	-	-	-	-	-	-	-	OprB
LZS3_k127_252104_12	290398.Csal_2792	0.0003006	46.0	COG1247@1|root,COG1247@2|Bacteria,1REV2@1224|Proteobacteria,1S893@1236|Gammaproteobacteria,1XRI2@135619|Oceanospirillales	135619|Oceanospirillales	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
LZS3_k127_253023_3	234267.Acid_4940	2.976e-139	472.0	COG1409@1|root,COG1657@1|root,COG4412@1|root,COG1409@2|Bacteria,COG1657@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K14647,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	-	-	CARDB,Peptidase_M30
LZS3_k127_253023_0	234267.Acid_1951	0.0	1124.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
LZS3_k127_253023_8	1267535.KB906767_gene889	1.46e-48	181.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	ermC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
LZS3_k127_253023_5	234267.Acid_7122	1.415e-73	270.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_7122|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_253023_6	234267.Acid_7083	1.627e-60	214.0	COG1778@1|root,COG1778@2|Bacteria,3Y5BY@57723|Acidobacteria	57723|Acidobacteria	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
LZS3_k127_253023_2	234267.Acid_3165	8.18e-156	512.0	COG2812@1|root,COG2812@2|Bacteria,3Y3C4@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
LZS3_k127_253023_9	1267535.KB906767_gene4256	3.231e-35	137.0	COG0718@1|root,COG0718@2|Bacteria,3Y5CB@57723|Acidobacteria	57723|Acidobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
LZS3_k127_253023_4	1340493.JNIF01000003_gene4003	9.796e-78	264.0	COG0353@1|root,COG0353@2|Bacteria,3Y31E@57723|Acidobacteria	57723|Acidobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
LZS3_k127_253023_1	1487953.JMKF01000028_gene1253	2.151e-179	597.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H9JN@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GAF,GGDEF,PAS_3,PAS_9,Response_reg
LZS3_k127_253023_10	1340493.JNIF01000003_gene2509	3.292e-05	49.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,OmpA,Plug,RHS_repeat
LZS3_k127_2538359_2	1121104.AQXH01000005_gene189	1.173e-165	533.0	COG0025@1|root,COG0025@2|Bacteria,4PKJ5@976|Bacteroidetes	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
LZS3_k127_2538359_3	243231.GSU3428	1.097e-34	142.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,42VS9@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
LZS3_k127_2538359_0	1267535.KB906767_gene470	2.66e-175	559.0	COG0247@1|root,COG0247@2|Bacteria,3Y6NT@57723|Acidobacteria	57723|Acidobacteria	C	Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
LZS3_k127_2538359_4	1267533.KB906734_gene3984	1.731e-31	130.0	COG1664@1|root,COG1664@2|Bacteria,3Y49V@57723|Acidobacteria,2JJ4E@204432|Acidobacteriia	204432|Acidobacteriia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS3_k127_2538359_1	234267.Acid_1514	1.897e-174	571.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2550002_5	485913.Krac_2852	1.983e-123	406.0	COG2046@1|root,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of activated sulfate	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
LZS3_k127_2550002_8	234267.Acid_7933	3.225e-85	296.0	COG0175@1|root,COG0529@1|root,COG0175@2|Bacteria,COG0529@2|Bacteria,3Y5BG@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	1.8.4.10,1.8.4.8,2.7.1.25	ko:K00390,ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R02021,R04928	RC00002,RC00007,RC00078,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
LZS3_k127_2550002_9	234267.Acid_7933	2.722e-84	282.0	COG0175@1|root,COG0529@1|root,COG0175@2|Bacteria,COG0529@2|Bacteria,3Y5BG@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	1.8.4.10,1.8.4.8,2.7.1.25	ko:K00390,ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R02021,R04928	RC00002,RC00007,RC00078,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
LZS3_k127_2550002_12	1134413.ANNK01000085_gene430	6.355e-41	162.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,4HB6B@91061|Bacilli,1ZDNY@1386|Bacillus	91061|Bacilli	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
LZS3_k127_2550002_6	572477.Alvin_0992	8.143e-110	363.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,1RMPE@1236|Gammaproteobacteria,1WWZS@135613|Chromatiales	135613|Chromatiales	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
LZS3_k127_2550002_14	234267.Acid_3845	2.448e-32	134.0	COG0558@1|root,COG0558@2|Bacteria,3Y4S5@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS3_k127_2550002_11	234267.Acid_3846	5.455e-56	201.0	2FCIR@1|root,344N3@2|Bacteria,3Y8MF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2550002_13	234267.Acid_3847	9.681e-38	151.0	COG1434@1|root,COG1434@2|Bacteria,3Y8M4@57723|Acidobacteria	57723|Acidobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
LZS3_k127_2550002_4	234267.Acid_3848	3.667e-189	611.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
LZS3_k127_2550002_3	234267.Acid_0453	1.5e-229	729.0	COG1132@1|root,COG1132@2|Bacteria,3Y2ZR@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter transmembrane	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
LZS3_k127_2550002_17	1201290.M902_0663	4.05e-08	56.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
LZS3_k127_2550002_10	1123508.JH636439_gene1827	5.091e-71	254.0	COG3055@1|root,COG3055@2|Bacteria,2IY7R@203682|Planctomycetes	203682|Planctomycetes	E	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
LZS3_k127_2550002_7	768671.ThimaDRAFT_4597	2.977e-94	329.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,1R0C0@1224|Proteobacteria,1SE9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2550002_2	1267535.KB906767_gene605	3.355e-234	735.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,3Y2I9@57723|Acidobacteria,2JHNT@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
LZS3_k127_2550002_1	344747.PM8797T_12748	6.058e-251	812.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2IYHP@203682|Planctomycetes	203682|Planctomycetes	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS3_k127_2550002_16	243090.RB1156	2.735e-10	72.0	COG4961@1|root,COG4961@2|Bacteria,2IXIS@203682|Planctomycetes	203682|Planctomycetes	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
LZS3_k127_2550002_0	234267.Acid_7204	0.0	1023.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y2P5@57723|Acidobacteria	57723|Acidobacteria	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS3_k127_2590540_7	234267.Acid_6618	3.189e-38	153.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	GNVR,Wzz
LZS3_k127_2590540_5	644282.Deba_0611	1.067e-92	318.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,42P3H@68525|delta/epsilon subdivisions,2WK0J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_2590540_6	234267.Acid_7178	3.239e-57	216.0	COG0728@1|root,COG0728@2|Bacteria	2|Bacteria	M	peptidoglycan biosynthetic process	pslK	-	-	ko:K21004	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	MVIN
LZS3_k127_2590540_2	234267.Acid_6619	4.62e-113	381.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	PglL_A,Wzy_C,Wzy_C_2
LZS3_k127_2590540_4	234267.Acid_6620	1.01e-93	325.0	COG0438@1|root,COG0438@2|Bacteria,3Y4F9@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_2590540_9	661478.OP10G_4515	1.124e-11	78.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_2590540_1	1340493.JNIF01000004_gene1020	1.221e-156	505.0	COG2223@1|root,COG2223@2|Bacteria,3Y3PZ@57723|Acidobacteria	57723|Acidobacteria	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_2590540_3	880070.Cycma_4442	2.053e-104	350.0	28KEJ@1|root,2Z9QB@2|Bacteria,4P1U9@976|Bacteroidetes,47TF2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2590540_8	1232410.KI421416_gene2621	2.077e-23	107.0	2EF9T@1|root,3392P@2|Bacteria,1P8J3@1224|Proteobacteria,4324V@68525|delta/epsilon subdivisions,2WYC0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2590540_0	1123242.JH636434_gene3703	5.862e-182	589.0	arCOG10801@1|root,2Z9IC@2|Bacteria,2J23R@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2590540_11	118168.MC7420_445	4.8e-06	58.0	COG1215@1|root,COG1215@2|Bacteria,1FZZM@1117|Cyanobacteria,1H7GF@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_2590540_10	754477.Q7C_2297	3.847e-06	53.0	COG0438@1|root,COG0438@2|Bacteria,1RJJE@1224|Proteobacteria	1224|Proteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
LZS3_k127_2594372_2	1340493.JNIF01000004_gene1085	8.259e-22	100.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K06370	-	-	-	-	ko00000	-	-	-	CW_binding_1,Flg_new,GGDEF,Gram_pos_anchor,LysM,WD40
LZS3_k127_2594372_0	1340493.JNIF01000004_gene1086	1.951e-282	893.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2
LZS3_k127_2594372_1	1340493.JNIF01000004_gene1087	1.11e-176	563.0	COG4102@1|root,COG4102@2|Bacteria	1340493.JNIF01000004_gene1087|-	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2659540_7	1267535.KB906767_gene2658	1.184e-66	250.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cadherin-like,DUF4091,F5_F8_type_C,Laminin_G_3,SLH
LZS3_k127_2659540_11	869210.Marky_1921	1.551e-33	133.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_2659540_3	472759.Nhal_3495	3.478e-155	505.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,1WZJC@135613|Chromatiales	135613|Chromatiales	E	PFAM peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
LZS3_k127_2659540_1	1340493.JNIF01000003_gene3900	3.757e-197	627.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_2659540_13	1267535.KB906767_gene3045	6.381e-22	103.0	2FHZB@1|root,349S8@2|Bacteria,3Y8KS@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2659540_10	234267.Acid_6678	1.406e-47	184.0	COG2823@1|root,COG2823@2|Bacteria,3Y7ZV@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2659540_15	34839.XP_005403306.1	0.0008324	47.0	KOG0980@1|root,KOG0980@2759|Eukaryota,38H1K@33154|Opisthokonta,3BBY2@33208|Metazoa,3CR9H@33213|Bilateria,47Z4J@7711|Chordata,49505@7742|Vertebrata,3J5G6@40674|Mammalia,35F4X@314146|Euarchontoglires,4PS6U@9989|Rodentia	33208|Metazoa	Z	Huntingtin-interacting protein 1-related protein	HIP1R	GO:0001726,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005543,GO:0005546,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005886,GO:0005905,GO:0005938,GO:0006810,GO:0006839,GO:0006897,GO:0006898,GO:0006919,GO:0006996,GO:0007005,GO:0007006,GO:0007275,GO:0008064,GO:0008092,GO:0008150,GO:0008289,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010604,GO:0010638,GO:0010639,GO:0010640,GO:0010641,GO:0010646,GO:0010647,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012505,GO:0012506,GO:0014069,GO:0016020,GO:0016043,GO:0016192,GO:0016324,GO:0017124,GO:0019222,GO:0019904,GO:0022607,GO:0023051,GO:0023056,GO:0030100,GO:0030135,GO:0030136,GO:0030162,GO:0030276,GO:0030425,GO:0030659,GO:0030662,GO:0030665,GO:0030674,GO:0030832,GO:0030833,GO:0030837,GO:0031090,GO:0031252,GO:0031253,GO:0031256,GO:0031323,GO:0031325,GO:0031333,GO:0031334,GO:0031410,GO:0031647,GO:0031982,GO:0032051,GO:0032092,GO:0032268,GO:0032270,GO:0032271,GO:0032272,GO:0032279,GO:0032501,GO:0032502,GO:0032535,GO:0032587,GO:0032838,GO:0032839,GO:0032879,GO:0032956,GO:0032970,GO:0033043,GO:0034315,GO:0034316,GO:0034622,GO:0035091,GO:0035615,GO:0036477,GO:0038024,GO:0042058,GO:0042802,GO:0042803,GO:0042981,GO:0042995,GO:0043005,GO:0043025,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043167,GO:0043168,GO:0043197,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043254,GO:0043280,GO:0043281,GO:0043325,GO:0043393,GO:0043933,GO:0044057,GO:0044058,GO:0044085,GO:0044087,GO:0044089,GO:0044093,GO:0044297,GO:0044309,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044877,GO:0045177,GO:0045202,GO:0045742,GO:0045807,GO:0045862,GO:0046902,GO:0046982,GO:0046983,GO:0048259,GO:0048260,GO:0048268,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0051015,GO:0051046,GO:0051049,GO:0051050,GO:0051098,GO:0051099,GO:0051125,GO:0051126,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051493,GO:0051494,GO:0052547,GO:0052548,GO:0055123,GO:0060090,GO:0060255,GO:0060453,GO:0060548,GO:0060627,GO:0061024,GO:0065003,GO:0065007,GO:0065008,GO:0065009,GO:0071840,GO:0071944,GO:0080025,GO:0080090,GO:0090066,GO:0090559,GO:0097060,GO:0097447,GO:0097458,GO:0097708,GO:0098588,GO:0098590,GO:0098657,GO:0098748,GO:0098794,GO:0098805,GO:0098984,GO:0099568,GO:0099572,GO:0110053,GO:0120025,GO:0120038,GO:0120111,GO:1901028,GO:1901030,GO:1901184,GO:1901186,GO:1901981,GO:1902903,GO:1902904,GO:1902936,GO:1905443,GO:1905445,GO:2000116,GO:2000369,GO:2000370,GO:2000586,GO:2000588,GO:2001056,GO:2001233,GO:2001235	-	ko:K04559,ko:K20040	ko05016,map05016	-	-	-	ko00000,ko00001,ko04131	-	-	-	ANTH,HIP1_clath_bdg,I_LWEQ
LZS3_k127_2659540_9	234267.Acid_3472	1.67e-56	203.0	COG0500@1|root,COG2226@2|Bacteria,3Y5QZ@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_2659540_5	234267.Acid_3715	4.633e-89	316.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_2659540_6	234267.Acid_4025	4.209e-78	270.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	CheW,NMT1,NMT1_2,OmpA,Phosphonate-bd,Response_reg,Sigma70_r2
LZS3_k127_2659540_12	1340493.JNIF01000003_gene2579	3.834e-28	124.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	Abi
LZS3_k127_2659540_4	234267.Acid_1486	3.453e-138	452.0	COG0182@1|root,COG0182@2|Bacteria,3Y2TR@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
LZS3_k127_2659540_2	1267535.KB906767_gene480	1.638e-180	578.0	COG2204@1|root,COG2204@2|Bacteria,3Y3T2@57723|Acidobacteria,2JIG9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_2659540_0	234267.Acid_1646	6.822e-269	858.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,3Y3X4@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
LZS3_k127_266843_4	1449126.JQKL01000011_gene3561	1.348e-59	223.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,247X6@186801|Clostridia,269PS@186813|unclassified Clostridiales	186801|Clostridia	S	Conserved hypothetical protein 698	yeiH	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
LZS3_k127_266843_1	330214.NIDE1821	1.322e-109	363.0	COG0031@1|root,COG0031@2|Bacteria,3J0HD@40117|Nitrospirae	40117|Nitrospirae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_266843_3	644282.Deba_2007	4.452e-65	232.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,42N2E@68525|delta/epsilon subdivisions,2WJFV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF4339
LZS3_k127_266843_2	215803.DB30_1759	3.55e-94	329.0	COG2234@1|root,COG2234@2|Bacteria,1R77P@1224|Proteobacteria,438J4@68525|delta/epsilon subdivisions,2X8TJ@28221|Deltaproteobacteria,2YX3Q@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS3_k127_266843_0	1340493.JNIF01000003_gene4382	3.542e-132	435.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_266843_5	1515746.HR45_16670	7.333e-30	136.0	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,1RP7I@1236|Gammaproteobacteria,2QBH7@267890|Shewanellaceae	1236|Gammaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_2674180_3	1123242.JH636434_gene5302	2.51e-66	244.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2674180_4	506534.Rhein_3069	0.0001728	51.0	COG5646@1|root,COG5646@2|Bacteria,1N8IH@1224|Proteobacteria,1SDPM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
LZS3_k127_2674180_2	1047013.AQSP01000125_gene2637	3.451e-95	334.0	COG0823@1|root,COG4946@1|root,COG0823@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidohydro_1,PD40,PG_binding_1,Pkinase,TolB_N
LZS3_k127_2674180_0	204669.Acid345_2828	3.782e-231	731.0	COG1132@1|root,COG1132@2|Bacteria,3Y2XY@57723|Acidobacteria,2JHZ0@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
LZS3_k127_2674180_1	1047013.AQSP01000105_gene1463	9.547e-151	488.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase,FCD
LZS3_k127_2678395_7	1219035.NT2_01_05540	6.524e-135	442.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,2KCTY@204457|Sphingomonadales	204457|Sphingomonadales	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6,4.2.1.8,5.1.2.2	ko:K01684,ko:K01781,ko:K08323	ko00040,ko00052,ko00627,ko01100,ko01120,map00040,map00052,map00627,map01100,map01120	M00061,M00552	R03033,R03791,R04161,R05606	RC00543,RC00998	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_2678395_6	251221.35212852	1.395e-135	452.0	COG4715@1|root,COG4715@2|Bacteria	2|Bacteria	S	zinc ion binding	CP_1020	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
LZS3_k127_2678395_4	1210884.HG799468_gene13690	1.117e-181	584.0	COG3653@1|root,COG3653@2|Bacteria,2IXWQ@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS3_k127_2678395_13	1185876.BN8_03564	6.595e-83	290.0	COG1312@1|root,COG1312@2|Bacteria,4NIMS@976|Bacteroidetes,47JVK@768503|Cytophagia	976|Bacteroidetes	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
LZS3_k127_2678395_15	926566.Terro_3979	9.177e-71	258.0	COG0520@1|root,COG0520@2|Bacteria,3Y3UN@57723|Acidobacteria,2JK05@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
LZS3_k127_2678395_12	1089544.KB912942_gene2511	1.151e-90	310.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS3_k127_2678395_20	1267535.KB906767_gene3547	5.924e-36	143.0	COG0576@1|root,COG0576@2|Bacteria,3Y54K@57723|Acidobacteria,2JJMY@204432|Acidobacteriia	204432|Acidobacteriia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS3_k127_2678395_10	1123392.AQWL01000007_gene926	3.889e-130	427.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,1KRI6@119069|Hydrogenophilales	119069|Hydrogenophilales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS3_k127_2678395_23	344747.PM8797T_30581	6.031e-31	136.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4433,MR_MLE_C
LZS3_k127_2678395_27	1121930.AQXG01000010_gene3062	5.742e-23	103.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_2678395_9	1121930.AQXG01000010_gene3062	8.924e-132	427.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_2678395_21	29581.BW37_01975	7.517e-33	134.0	COG3339@1|root,COG3339@2|Bacteria,1MZR5@1224|Proteobacteria,2VV8K@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
LZS3_k127_2678395_32	1267535.KB906767_gene4779	1.249e-11	74.0	2DFMP@1|root,2ZSBB@2|Bacteria,3Y8UP@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2678395_3	234267.Acid_0040	2.943e-194	612.0	COG1960@1|root,COG1960@2|Bacteria,3Y2FM@57723|Acidobacteria	57723|Acidobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_2678395_22	1173028.ANKO01000075_gene2969	8.493e-33	133.0	COG3631@1|root,COG3631@2|Bacteria,1GAK6@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
LZS3_k127_2678395_28	234267.Acid_0338	1.394e-21	97.0	COG1558@1|root,COG1558@2|Bacteria,3Y538@57723|Acidobacteria	57723|Acidobacteria	N	flagellar basal-body rod protein FlgC	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
LZS3_k127_2678395_30	234267.Acid_0327	1.469e-20	97.0	COG1344@1|root,COG1344@2|Bacteria,3Y4AW@57723|Acidobacteria	57723|Acidobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
LZS3_k127_2678395_14	338963.Pcar_1476	1.499e-80	287.0	28N9P@1|root,2ZBDN@2|Bacteria,1R70P@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
LZS3_k127_2678395_26	1433126.BN938_1424	1.652e-28	128.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	XK27_03530	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,rRNA_methylase
LZS3_k127_2678395_25	234267.Acid_7539	2.425e-29	119.0	COG0724@1|root,COG0724@2|Bacteria,3Y59V@57723|Acidobacteria	57723|Acidobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_2678395_11	264732.Moth_0831	7.03e-112	378.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,42IC3@68295|Thermoanaerobacterales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
LZS3_k127_2678395_8	1123242.JH636438_gene5875	6.844e-134	440.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_2678395_19	1267533.KB906733_gene2860	4.397e-39	160.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
LZS3_k127_2678395_17	1101192.KB910516_gene3343	3.573e-49	187.0	COG2227@1|root,COG2227@2|Bacteria,1RI5H@1224|Proteobacteria,2U966@28211|Alphaproteobacteria,1JRAM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
LZS3_k127_2678395_2	552811.Dehly_1510	4.001e-199	632.0	COG4108@1|root,COG4108@2|Bacteria	2|Bacteria	J	protein-containing complex disassembly	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837,ko:K07133	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
LZS3_k127_2678395_31	1238182.C882_0930	2.977e-18	89.0	COG1734@1|root,COG1734@2|Bacteria,1N7D8@1224|Proteobacteria,2UHGM@28211|Alphaproteobacteria,2JTAS@204441|Rhodospirillales	204441|Rhodospirillales	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS3_k127_2678395_24	999541.bgla_1g26300	8.071e-31	132.0	COG3618@1|root,COG3618@2|Bacteria,1R3QY@1224|Proteobacteria,2WFBV@28216|Betaproteobacteria,1K6JV@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_2678395_5	1267535.KB906767_gene5242	1.218e-157	500.0	COG3119@1|root,COG3119@2|Bacteria,3Y654@57723|Acidobacteria	57723|Acidobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_2678395_0	234267.Acid_6181	1.08e-286	900.0	COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_2678395_1	234267.Acid_6180	6.341e-240	761.0	COG3379@1|root,COG3379@2|Bacteria,3Y7CR@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_2678395_16	234267.Acid_6179	4.861e-64	229.0	2DZX2@1|root,32VM6@2|Bacteria,3Y88Y@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2678395_18	314266.SKA58_06240	5.528e-44	174.0	COG4206@1|root,COG4206@2|Bacteria,1MUZG@1224|Proteobacteria,2TUNP@28211|Alphaproteobacteria,2K1AW@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
LZS3_k127_2683150_16	1210884.HG799463_gene10078	4.851e-05	46.0	COG1228@1|root,COG1228@2|Bacteria,2J1M0@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS3_k127_2683150_3	1340493.JNIF01000004_gene553	6.157e-93	315.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
LZS3_k127_2683150_4	1340493.JNIF01000004_gene554	1.009e-88	310.0	COG1052@1|root,COG1052@2|Bacteria,3Y2MD@57723|Acidobacteria	2|Bacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_2683150_2	1267535.KB906767_gene18	2.976e-164	535.0	COG0038@1|root,COG0038@2|Bacteria,3Y2G4@57723|Acidobacteria,2JIJC@204432|Acidobacteriia	204432|Acidobacteriia	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
LZS3_k127_2683150_8	1267535.KB906767_gene19	6.534e-55	209.0	COG0457@1|root,COG0457@2|Bacteria	1267535.KB906767_gene19|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2683150_12	234267.Acid_6313	1.11e-23	103.0	COG1639@1|root,COG1639@2|Bacteria,3Y8JW@57723|Acidobacteria	57723|Acidobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
LZS3_k127_2683150_14	234267.Acid_6313	1.242e-18	88.0	COG1639@1|root,COG1639@2|Bacteria,3Y8JW@57723|Acidobacteria	57723|Acidobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
LZS3_k127_2683150_10	234267.Acid_2812	5.229e-34	143.0	COG0822@1|root,COG0822@2|Bacteria,3Y4B9@57723|Acidobacteria	57723|Acidobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
LZS3_k127_2683150_6	309807.SRU_0977	2.498e-82	295.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2683150_15	1089550.ATTH01000001_gene1889	1.16e-17	96.0	COG0729@1|root,COG0729@2|Bacteria,4PF0B@976|Bacteroidetes,1FJXS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
LZS3_k127_2683150_5	1123508.JH636439_gene1117	2.358e-88	302.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS3_k127_2683150_0	1123023.JIAI01000001_gene6504	6.513e-221	694.0	COG0591@1|root,COG0591@2|Bacteria,2HEKH@201174|Actinobacteria,4DZCV@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS3_k127_2683150_7	1123023.JIAI01000001_gene6507	5.666e-70	248.0	COG2971@1|root,COG2971@2|Bacteria,2HURV@201174|Actinobacteria,4E7XW@85010|Pseudonocardiales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
LZS3_k127_2683150_1	1267535.KB906767_gene2890	5.732e-173	548.0	COG1063@1|root,COG1063@2|Bacteria,3Y3UU@57723|Acidobacteria,2JI46@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_2683150_13	240015.ACP_2535	2.168e-20	97.0	COG0071@1|root,COG0071@2|Bacteria,3Y8FE@57723|Acidobacteria,2JNDQ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934,HSP20
LZS3_k127_2683150_9	234267.Acid_7445	7.116e-54	203.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria	57723|Acidobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_2683150_11	525897.Dbac_1192	8.785e-24	101.0	COG1226@1|root,COG1226@2|Bacteria,1R97G@1224|Proteobacteria,42Y5Z@68525|delta/epsilon subdivisions,2WUMH@28221|Deltaproteobacteria,2METD@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Ion transport protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans
LZS3_k127_2703145_11	324057.Pjdr2_0960	5.049e-92	312.0	COG1262@1|root,COG1262@2|Bacteria,1TT4R@1239|Firmicutes,4HA8D@91061|Bacilli,26RR0@186822|Paenibacillaceae	91061|Bacilli	S	Sulfatase-modifying factor enzyme 1	pkn1	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
LZS3_k127_2703145_6	1303518.CCALI_01261	3.292e-139	454.0	COG3186@1|root,COG3186@2|Bacteria	2|Bacteria	E	Phenylalanine-4-hydroxylase	phhA	GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0006082,GO:0006520,GO:0006558,GO:0006559,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016714,GO:0017144,GO:0019439,GO:0019752,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902221,GO:1902222	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
LZS3_k127_2703145_10	207559.Dde_0462	1.29e-93	327.0	COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,42P3P@68525|delta/epsilon subdivisions,2WK16@28221|Deltaproteobacteria,2MAPY@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_2703145_7	234267.Acid_7363	2.139e-129	428.0	COG3359@1|root,COG3359@2|Bacteria,3Y6WT@57723|Acidobacteria	57723|Acidobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
LZS3_k127_2703145_0	234267.Acid_0769	0.0	1122.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,3Y61D@57723|Acidobacteria	57723|Acidobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
LZS3_k127_2703145_23	679926.Mpet_1489	2.8e-07	59.0	COG0639@1|root,COG5607@1|root,arCOG01143@2157|Archaea,arCOG05139@2157|Archaea,2XUDG@28890|Euryarchaeota,2NAJW@224756|Methanomicrobia	224756|Methanomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,Metallophos_2
LZS3_k127_2703145_21	1267535.KB906767_gene3692	3.197e-13	75.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
LZS3_k127_2703145_4	234267.Acid_6686	1.723e-170	550.0	COG0248@1|root,COG0248@2|Bacteria,3Y3H5@57723|Acidobacteria	57723|Acidobacteria	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
LZS3_k127_2703145_12	485913.Krac_9228	1.11e-86	292.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
LZS3_k127_2703145_16	485913.Krac_9227	4.676e-64	228.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
LZS3_k127_2703145_17	1254432.SCE1572_39420	7.775e-59	211.0	COG0398@1|root,COG0398@2|Bacteria,1N8PZ@1224|Proteobacteria,42R8S@68525|delta/epsilon subdivisions,2WNPD@28221|Deltaproteobacteria,2YVAY@29|Myxococcales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS3_k127_2703145_8	555088.DealDRAFT_0546	2.852e-110	370.0	COG1680@1|root,COG1680@2|Bacteria,1V18R@1239|Firmicutes	1239|Firmicutes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_2703145_19	234267.Acid_0739	1.512e-36	161.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,3Y3S3@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	NHL
LZS3_k127_2703145_2	1382359.JIAL01000001_gene1736	1.64e-219	685.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
LZS3_k127_2703145_3	234267.Acid_0912	3.973e-186	592.0	COG1249@1|root,COG1249@2|Bacteria,3Y2M8@57723|Acidobacteria	57723|Acidobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS3_k127_2703145_13	234267.Acid_0913	6.595e-75	259.0	COG0321@1|root,COG0321@2|Bacteria,3Y448@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
LZS3_k127_2703145_9	1121920.AUAU01000004_gene789	9.256e-107	367.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS3_k127_2703145_14	1382304.JNIL01000001_gene1207	2.714e-72	254.0	COG0179@1|root,COG0179@2|Bacteria,1TUD1@1239|Firmicutes,4HBI1@91061|Bacilli	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
LZS3_k127_2703145_5	1267535.KB906767_gene3130	2.359e-160	515.0	COG2271@1|root,COG2271@2|Bacteria,3Y5MH@57723|Acidobacteria,2JMY4@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_2703145_15	1340493.JNIF01000003_gene1949	9.998e-72	255.0	COG0526@1|root,COG0526@2|Bacteria,3Y64J@57723|Acidobacteria	57723|Acidobacteria	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_2703145_1	1340493.JNIF01000004_gene277	3.642e-238	745.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_2703145_18	1340493.JNIF01000003_gene4261	1.543e-55	200.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
LZS3_k127_2703145_22	1340493.JNIF01000003_gene4260	8.304e-11	68.0	COG4233@1|root,COG4233@2|Bacteria	2|Bacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084,ko:K06888	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
LZS3_k127_2720791_9	1267535.KB906767_gene4506	1.204e-31	125.0	COG0103@1|root,COG0103@2|Bacteria,3Y4IK@57723|Acidobacteria,2JJ7P@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS3_k127_2720791_3	1267535.KB906767_gene4505	2.931e-110	363.0	COG0052@1|root,COG0052@2|Bacteria,3Y3K2@57723|Acidobacteria,2JI0A@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
LZS3_k127_2720791_5	234267.Acid_0905	3.251e-80	274.0	COG0264@1|root,COG0264@2|Bacteria,3Y3BT@57723|Acidobacteria	57723|Acidobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
LZS3_k127_2720791_6	264462.Bd3783	4.567e-78	269.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2MSR9@213481|Bdellovibrionales,2WJDF@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS3_k127_2720791_7	234267.Acid_0903	3.583e-68	236.0	COG0233@1|root,COG0233@2|Bacteria,3Y4AP@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
LZS3_k127_2720791_4	1379270.AUXF01000005_gene644	1.163e-80	274.0	28NKC@1|root,2ZBM7@2|Bacteria,1ZUHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2720791_1	340099.Teth39_0432	2.086e-156	509.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,42FA0@68295|Thermoanaerobacterales	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
LZS3_k127_2720791_2	234267.Acid_4935	4.283e-119	401.0	COG1253@1|root,COG1253@2|Bacteria,3Y2KE@57723|Acidobacteria	57723|Acidobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
LZS3_k127_2720791_0	497964.CfE428DRAFT_2120	1.944e-309	962.0	COG4993@1|root,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
LZS3_k127_2727516_11	1047013.AQSP01000128_gene418	2.27e-44	164.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
LZS3_k127_2727516_13	760192.Halhy_1003	4.328e-42	169.0	2DBK2@1|root,2Z9Q1@2|Bacteria,4NET4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2727516_16	234267.Acid_1755	8.235e-38	150.0	COG2197@1|root,COG2197@2|Bacteria,3Y2WY@57723|Acidobacteria	57723|Acidobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_2727516_6	1125863.JAFN01000001_gene3056	8.366e-87	298.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2WK0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
LZS3_k127_2727516_19	1122927.KB895414_gene4953	5.768e-35	143.0	COG2345@1|root,COG2345@2|Bacteria,1V5Q5@1239|Firmicutes,4HHMX@91061|Bacilli,26U3B@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,HTH_DeoR
LZS3_k127_2727516_17	1267535.KB906767_gene197	5.769e-37	141.0	COG0316@1|root,COG0316@2|Bacteria,3Y518@57723|Acidobacteria,2JJGN@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
LZS3_k127_2727516_5	747365.Thena_1710	2.115e-97	331.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,42F86@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
LZS3_k127_2727516_4	1267535.KB906767_gene1295	2.393e-98	328.0	COG1692@1|root,COG1692@2|Bacteria,3Y3YJ@57723|Acidobacteria,2JIAY@204432|Acidobacteriia	204432|Acidobacteriia	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
LZS3_k127_2727516_21	562970.Btus_2299	2.203e-07	57.0	COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,278K2@186823|Alicyclobacillaceae	91061|Bacilli	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
LZS3_k127_2727516_22	204669.Acid345_0719	6.113e-05	49.0	2ESG3@1|root,33K0W@2|Bacteria,3Y5YI@57723|Acidobacteria,2JK4B@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2727516_1	204669.Acid345_0718	1.012e-168	553.0	COG0072@1|root,COG0072@2|Bacteria,3Y353@57723|Acidobacteria,2JIM2@204432|Acidobacteriia	204432|Acidobacteriia	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB
LZS3_k127_2727516_3	880073.Calab_3704	3.6e-104	357.0	COG0016@1|root,COG0016@2|Bacteria,2NNNT@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415,iJN746.PP_2469,iSSON_1240.SSON_1444,iYL1228.KPN_02176	Phe_tRNA-synt_N,tRNA-synt_2d
LZS3_k127_2727516_15	204669.Acid345_0715	4.092e-39	151.0	COG0292@1|root,COG0292@2|Bacteria,3Y4SW@57723|Acidobacteria,2JJJ2@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
LZS3_k127_2727516_20	56780.SYN_01719	3.97e-14	75.0	COG0291@1|root,COG0291@2|Bacteria,1QDQ4@1224|Proteobacteria,42VSG@68525|delta/epsilon subdivisions,2WREY@28221|Deltaproteobacteria,2MSHX@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
LZS3_k127_2727516_24	28072.Nos7524_3008	0.0004311	48.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3452@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3452@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1HMEM@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
LZS3_k127_2727516_9	519989.ECTPHS_09233	1.59e-62	233.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria,1WZ40@135613|Chromatiales	135613|Chromatiales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
LZS3_k127_2727516_18	344747.PM8797T_13433	1.19e-36	145.0	2E13H@1|root,32WIX@2|Bacteria,2J0HQ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2727516_7	1005048.CFU_1088	1.905e-84	295.0	COG0644@1|root,COG0644@2|Bacteria,1PQI2@1224|Proteobacteria,2VUCT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS3_k127_2727516_8	1131814.JAFO01000001_gene4810	2.916e-77	269.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,2TT9D@28211|Alphaproteobacteria,3EXYN@335928|Xanthobacteraceae	28211|Alphaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
LZS3_k127_2727516_23	67373.JOBF01000001_gene5984	0.0001088	45.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
LZS3_k127_2727516_14	1123242.JH636434_gene4245	3.509e-40	155.0	COG3795@1|root,COG3795@2|Bacteria,2J10A@203682|Planctomycetes	203682|Planctomycetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
LZS3_k127_2727516_2	1117379.BABA_04409	6.547e-157	499.0	COG3865@1|root,COG3865@2|Bacteria,1TP7B@1239|Firmicutes,4HDPM@91061|Bacilli,1ZR5K@1386|Bacillus	91061|Bacilli	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
LZS3_k127_2727516_10	1047013.AQSP01000076_gene1470	3.071e-46	178.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_2727516_0	1114970.PSF113_1697	7.239e-169	535.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,1RNNH@1236|Gammaproteobacteria,1YSUC@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
LZS3_k127_2727516_12	391626.OAN307_c18160	2.07e-43	164.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2U05W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
LZS3_k127_2736910_5	234267.Acid_4033	1.276e-33	150.0	COG2304@1|root,COG2304@2|Bacteria,3Y3DR@57723|Acidobacteria	57723|Acidobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2736910_0	1267535.KB906767_gene4473	4.498e-112	395.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF389,FecR,Laminin_G_3
LZS3_k127_2736910_3	1267534.KB906758_gene2227	7.422e-67	236.0	COG3571@1|root,COG3571@2|Bacteria,3Y7N8@57723|Acidobacteria,2JMUD@204432|Acidobacteriia	204432|Acidobacteriia	S	Alpha/beta hydrolase family	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	-
LZS3_k127_2736910_1	682795.AciX8_1498	8.011e-106	358.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	capM	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_2736910_4	204669.Acid345_0263	1.451e-40	162.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
LZS3_k127_2736910_6	234267.Acid_0823	7.012e-27	113.0	COG1278@1|root,COG1278@2|Bacteria,3Y8IF@57723|Acidobacteria	57723|Acidobacteria	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS3_k127_2736910_2	204669.Acid345_1043	2.687e-101	346.0	COG2379@1|root,COG2379@2|Bacteria,3Y2XC@57723|Acidobacteria,2JID2@204432|Acidobacteriia	204432|Acidobacteriia	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
LZS3_k127_2794628_0	234267.Acid_6135	1.098e-218	688.0	COG0457@1|root,COG0457@2|Bacteria,3Y3WM@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
LZS3_k127_2794628_1	234267.Acid_1306	1.582e-191	638.0	COG1629@1|root,COG1629@2|Bacteria,3Y99U@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_2794628_2	1340493.JNIF01000004_gene980	5.89e-54	195.0	COG2823@1|root,COG2823@2|Bacteria,3Y41W@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS3_k127_2796872_6	1417296.U879_17160	3.228e-110	372.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
LZS3_k127_2796872_12	1267535.KB906767_gene4949	7.86e-08	59.0	2FIG5@1|root,34A8B@2|Bacteria,3Y8GN@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2796872_5	240015.ACP_1704	3.102e-116	384.0	COG0668@1|root,COG0668@2|Bacteria,3Y4K3@57723|Acidobacteria,2JJAD@204432|Acidobacteriia	57723|Acidobacteria	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
LZS3_k127_2796872_3	1267533.KB906739_gene2541	3.692e-155	497.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
LZS3_k127_2796872_1	234267.Acid_7693	5.214e-281	876.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
LZS3_k127_2796872_7	886293.Sinac_3667	1.709e-94	313.0	COG3880@1|root,COG3880@2|Bacteria,2IYYJ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
LZS3_k127_2796872_0	886293.Sinac_3666	0.0	1234.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2IXNQ@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase, iron-sulfur binding subunit	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
LZS3_k127_2796872_2	1128421.JAGA01000003_gene2871	3.655e-223	699.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	nrfD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
LZS3_k127_2796872_9	1128421.JAGA01000003_gene2872	7.159e-70	240.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS3_k127_2796872_10	1340493.JNIF01000004_gene149	2.138e-67	235.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS3_k127_2796872_4	1128421.JAGA01000003_gene2874	5.943e-136	444.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2796872_8	234267.Acid_0496	6.236e-88	298.0	COG1999@1|root,COG1999@2|Bacteria,3Y3XH@57723|Acidobacteria	57723|Acidobacteria	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS3_k127_2915355_7	1267535.KB906767_gene4999	2.324e-106	350.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,CarboxypepD_reg,DUF1080,F5_F8_type_C,G5,G8,Glyco_hyd_101C,Glyco_hydro_101,Trypsin_2,YSIRK_signal,fn3
LZS3_k127_2915355_12	1121861.KB899926_gene2603	1.338e-42	164.0	COG2030@1|root,COG2030@2|Bacteria,1REMU@1224|Proteobacteria,2U7CT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
LZS3_k127_2915355_4	240016.ABIZ01000001_gene764	3.454e-152	497.0	COG3119@1|root,COG3119@2|Bacteria,46ZJS@74201|Verrucomicrobia,2IVBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_2915355_3	234267.Acid_3250	1.26e-164	526.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	megL	-	2.5.1.48,2.5.1.49,4.4.1.11,4.4.1.8	ko:K01739,ko:K01740,ko:K01760,ko:K01761,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01287,R01288,R02408,R02508,R03217,R03260,R04770,R04859,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02821,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
LZS3_k127_2915355_16	204669.Acid345_0985	1.08e-06	53.0	COG0266@1|root,COG0266@2|Bacteria,3Y71J@57723|Acidobacteria,2JKGK@204432|Acidobacteriia	204432|Acidobacteriia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
LZS3_k127_2915355_5	760192.Halhy_1186	6.153e-151	489.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,1IVTA@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	3.5.1.32	ko:K01436,ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_2915355_1	143224.JQMD01000002_gene209	2.026e-201	646.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
LZS3_k127_2915355_2	251221.35214774	2.22e-165	554.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
LZS3_k127_2915355_14	1340493.JNIF01000004_gene670	4.494e-22	113.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_2,Calx-beta,Laminin_G_3,PA14,VPEP
LZS3_k127_2915355_13	797209.ZOD2009_21492	2.602e-34	146.0	COG1402@1|root,arCOG04536@2157|Archaea,2XWZU@28890|Euryarchaeota,23VFZ@183963|Halobacteria	183963|Halobacteria	H	protein, putative amidase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS3_k127_2915355_8	234267.Acid_4933	4.442e-81	284.0	COG2370@1|root,COG2370@2|Bacteria	2|Bacteria	O	cobalamin-transporting ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ,NicO
LZS3_k127_2915355_9	234267.Acid_7101	2.108e-78	269.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	lolD	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran
LZS3_k127_2915355_0	1340493.JNIF01000003_gene2715	8.465e-232	745.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	salY	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_2915355_6	234267.Acid_1435	2.551e-113	376.0	COG5621@1|root,COG5621@2|Bacteria	2|Bacteria	S	spheroidene biosynthetic process	attH	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
LZS3_k127_2915355_15	234267.Acid_7286	1.464e-14	77.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS3_k127_2915355_10	443152.MDG893_15295	4.059e-50	192.0	COG3181@1|root,COG3181@2|Bacteria,1N3HN@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
LZS3_k127_2917315_11	314285.KT71_15399	1.065e-40	162.0	2DC2A@1|root,2ZCM4@2|Bacteria,1RBXZ@1224|Proteobacteria,1SDKK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2917315_9	323850.Shew_1307	9.114e-59	219.0	2BRAN@1|root,32K96@2|Bacteria,1P197@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2917315_15	1267535.KB906767_gene5151	8.782e-05	48.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
LZS3_k127_2917315_13	1347086.CCBA010000012_gene2030	3.172e-06	49.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2917315_7	1340493.JNIF01000003_gene4787	7.875e-79	278.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
LZS3_k127_2917315_2	204669.Acid345_3774	6.76e-227	728.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria,2JI1K@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
LZS3_k127_2917315_5	530564.Psta_3944	5.166e-98	332.0	COG1858@1|root,COG1858@2|Bacteria,2IY7G@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS3_k127_2917315_10	344747.PM8797T_12993	1.471e-41	165.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS3_k127_2917315_1	234267.Acid_0223	3.14e-250	818.0	COG3523@1|root,COG3523@2|Bacteria,3Y3IQ@57723|Acidobacteria	57723|Acidobacteria	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
LZS3_k127_2917315_8	234267.Acid_0224	1.505e-62	223.0	COG3455@1|root,COG3455@2|Bacteria,3Y4ZZ@57723|Acidobacteria	57723|Acidobacteria	S	Type VI secretion system protein DotU	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU
LZS3_k127_2917315_3	234267.Acid_0225	2.883e-162	524.0	COG3522@1|root,COG3522@2|Bacteria,3Y3ZI@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
LZS3_k127_2917315_6	234267.Acid_0222	4.243e-89	323.0	COG0515@1|root,COG0515@2|Bacteria,3Y6PF@57723|Acidobacteria	57723|Acidobacteria	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_2917315_4	234267.Acid_7147	6.636e-130	425.0	COG0714@1|root,COG0714@2|Bacteria,3Y6Z3@57723|Acidobacteria	57723|Acidobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
LZS3_k127_2917315_0	234267.Acid_7146	2.795e-251	793.0	COG1916@1|root,COG1916@2|Bacteria,3Y6KT@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2933492_3	1267535.KB906767_gene5502	9.422e-113	374.0	COG1052@1|root,COG1052@2|Bacteria,3Y8C1@57723|Acidobacteria,2JNCS@204432|Acidobacteriia	204432|Acidobacteriia	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_2933492_1	1340493.JNIF01000003_gene3625	1.551e-123	403.0	COG2084@1|root,COG2084@2|Bacteria,3Y45W@57723|Acidobacteria	57723|Acidobacteria	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
LZS3_k127_2933492_0	234267.Acid_3343	2.975e-202	640.0	COG4948@1|root,COG4948@2|Bacteria,3Y61U@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_2933492_6	1267535.KB906767_gene349	1.251e-17	85.0	COG1254@1|root,COG1254@2|Bacteria,3Y55N@57723|Acidobacteria	57723|Acidobacteria	C	acylphosphatase activity	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
LZS3_k127_2933492_4	926566.Terro_0241	2.669e-66	238.0	COG0503@1|root,COG0503@2|Bacteria,3Y30R@57723|Acidobacteria,2JHP2@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
LZS3_k127_2933492_5	234267.Acid_7097	8.941e-65	233.0	COG1947@1|root,COG1947@2|Bacteria,3Y55D@57723|Acidobacteria	57723|Acidobacteria	I	GHMP kinases N terminal domain	-	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS3_k127_2933492_2	234267.Acid_7096	3.527e-120	391.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria	57723|Acidobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
LZS3_k127_2980426_1	1163389.OOM_0821	2.669e-132	435.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria	1224|Proteobacteria	Q	Non-ribosomal peptide synthetase modules and related proteins	-	-	6.3.2.14	ko:K02364	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R07644	RC00162,RC03046	ko00000,ko00001,ko01000,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
LZS3_k127_2980426_2	1038867.AXAY01000010_gene977	5.832e-55	204.0	COG0110@1|root,COG0110@2|Bacteria,1RAKB@1224|Proteobacteria,2U3JX@28211|Alphaproteobacteria,3K1GC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
LZS3_k127_2980426_5	1384049.CD29_20020	1.795e-20	102.0	COG1670@1|root,COG1670@2|Bacteria,1UZR2@1239|Firmicutes,4HC5N@91061|Bacilli,3IY61@400634|Lysinibacillus	91061|Bacilli	J	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
LZS3_k127_2980426_4	1173026.Glo7428_3718	1.212e-44	181.0	COG1749@1|root,COG1749@2|Bacteria,1G2ZW@1117|Cyanobacteria	1117|Cyanobacteria	N	Ig domain protein group 1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,DUF4082
LZS3_k127_2980426_3	1120948.KB903243_gene2394	4.322e-45	177.0	2E29A@1|root,30QXH@2|Bacteria,2H74E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2980426_6	1408310.JHUW01000001_gene1221	8.332e-19	96.0	COG0346@1|root,COG0346@2|Bacteria,4NV3A@976|Bacteroidetes,2FV4F@200643|Bacteroidia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
LZS3_k127_2980426_0	156889.Mmc1_0150	2.254e-153	504.0	COG3882@1|root,COG3882@2|Bacteria,1PNPC@1224|Proteobacteria,2TUY2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	HAD-superfamily phosphatase subfamily IIIC	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2982750_6	857087.Metme_2999	4.117e-38	147.0	29DWE@1|root,300UA@2|Bacteria,1RDK5@1224|Proteobacteria,1S3V9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
LZS3_k127_2982750_5	1340493.JNIF01000004_gene205	1.036e-62	229.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	strN	-	2.7.1.72,2.7.1.89	ko:K04343,ko:K07251,ko:K18844	ko00730,ko01100,map00730,map01100	M00766	R02134,R02225	RC00002,RC00017,RC00078	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	APH,Choline_kinase
LZS3_k127_2982750_7	1123386.AUIW01000003_gene1045	9.095e-14	77.0	COG1403@1|root,COG1403@2|Bacteria,1WICD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
LZS3_k127_2982750_3	936136.ARRT01000007_gene1060	6.712e-91	316.0	COG2333@1|root,COG2333@2|Bacteria,1RE10@1224|Proteobacteria,2U7SC@28211|Alphaproteobacteria,4BI87@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_2982750_1	1041159.AZUW01000062_gene3637	7.459e-190	616.0	COG1404@1|root,COG1404@2|Bacteria,1PSEZ@1224|Proteobacteria,2V4M5@28211|Alphaproteobacteria,4BFDK@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS3_k127_2982750_0	234267.Acid_7732	0.0	1576.0	COG0514@1|root,COG0550@1|root,COG0514@2|Bacteria,COG0550@2|Bacteria,3Y363@57723|Acidobacteria	57723|Acidobacteria	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	-	-	3.6.4.12,5.99.1.2	ko:K03169,ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RecQ_Zn_bind
LZS3_k127_2982750_4	926566.Terro_3979	2.518e-72	258.0	COG0520@1|root,COG0520@2|Bacteria,3Y3UN@57723|Acidobacteria,2JK05@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
LZS3_k127_2982750_2	1163409.UUA_08346	2.598e-105	372.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,1RXYW@1236|Gammaproteobacteria,1XD03@135614|Xanthomonadales	135614|Xanthomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS3_k127_3014587_41	234267.Acid_5978	1.036e-07	60.0	2EU62@1|root,33MNN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
LZS3_k127_3014587_1	1267535.KB906767_gene5437	8.869e-221	713.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,3Y2VV@57723|Acidobacteria,2JIJ7@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA ligase D, 3'-phosphoesterase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
LZS3_k127_3014587_24	1340493.JNIF01000003_gene2519	8.95e-56	211.0	COG0457@1|root,COG0457@2|Bacteria,3Y7UM@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS3_k127_3014587_14	401053.AciPR4_1374	2.099e-103	346.0	COG0535@1|root,COG0535@2|Bacteria,3Y3TY@57723|Acidobacteria,2JHZQ@204432|Acidobacteriia	204432|Acidobacteriia	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS3_k127_3014587_10	1267535.KB906767_gene656	5.385e-120	403.0	COG1032@1|root,COG1032@2|Bacteria,3Y2FN@57723|Acidobacteria,2JI6W@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS3_k127_3014587_3	1123073.KB899241_gene3063	5.778e-194	610.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,1RPIT@1236|Gammaproteobacteria,1X4XS@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_3014587_26	204669.Acid345_3850	7.496e-53	193.0	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria,2JJ89@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_3014587_39	682795.AciX8_0312	4.217e-15	83.0	COG5662@1|root,COG5662@2|Bacteria,3Y4JS@57723|Acidobacteria,2JJ7U@204432|Acidobacteriia	204432|Acidobacteriia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS3_k127_3014587_30	1340493.JNIF01000003_gene1921	5.268e-40	165.0	COG2885@1|root,COG2885@2|Bacteria,3Y425@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS3_k127_3014587_27	1340493.JNIF01000003_gene2789	3.515e-52	195.0	COG0030@1|root,COG0030@2|Bacteria,3Y3RQ@57723|Acidobacteria	57723|Acidobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
LZS3_k127_3014587_11	234267.Acid_4553	1.823e-119	396.0	COG0836@1|root,COG0836@2|Bacteria,3Y2W2@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
LZS3_k127_3014587_13	234267.Acid_4552	2.632e-108	361.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
LZS3_k127_3014587_5	471854.Dfer_0651	8.227e-155	503.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,47TDH@768503|Cytophagia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
LZS3_k127_3014587_2	234267.Acid_4453	4.583e-216	679.0	COG4948@1|root,COG4948@2|Bacteria,3Y6X2@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3014587_6	1122605.KB893637_gene3269	1.424e-152	516.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
LZS3_k127_3014587_22	234267.Acid_2963	8.48e-76	264.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS3_k127_3014587_9	1267535.KB906767_gene1678	1.035e-123	406.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_3014587_32	1298858.AUEL01000017_gene2818	2.467e-35	149.0	COG1649@1|root,COG1649@2|Bacteria,1R6SN@1224|Proteobacteria,2U2S1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3014587_8	661478.OP10G_3858	1.143e-124	410.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yrbE	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_3014587_37	1340493.JNIF01000003_gene1428	1.176e-18	92.0	COG4980@1|root,COG4980@2|Bacteria,3Y5IA@57723|Acidobacteria	57723|Acidobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS3_k127_3014587_19	357808.RoseRS_3864	2.231e-85	297.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi	200795|Chloroflexi	E	PFAM alanine racemase domain protein	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
LZS3_k127_3014587_17	234267.Acid_5361	4.435e-91	305.0	COG3910@1|root,COG3910@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
LZS3_k127_3014587_31	234267.Acid_3123	3.598e-38	154.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_3014587_4	234267.Acid_4577	1.735e-191	613.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
LZS3_k127_3014587_34	243231.GSU1762	1.019e-21	109.0	COG0457@1|root,COG0457@2|Bacteria,1QXNU@1224|Proteobacteria,43C4R@68525|delta/epsilon subdivisions,2X7F5@28221|Deltaproteobacteria,43SFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_2,TPR_8
LZS3_k127_3014587_21	234267.Acid_4237	1.226e-76	266.0	COG2386@1|root,COG2386@2|Bacteria,3Y3G1@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c-type biogenesis protein CcmB	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
LZS3_k127_3014587_23	234267.Acid_4236	8.245e-65	230.0	COG1131@1|root,COG1131@2|Bacteria,3Y4M9@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
LZS3_k127_3014587_28	1340493.JNIF01000003_gene4702	1.716e-50	198.0	28K54@1|root,2Z9TW@2|Bacteria,3Y3Z7@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3014587_33	1267535.KB906767_gene3998	7.4e-23	102.0	2EFR0@1|root,339H2@2|Bacteria,3Y5M9@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3014587_0	234267.Acid_4232	1.529e-281	880.0	COG1138@1|root,COG1138@2|Bacteria,3Y40N@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
LZS3_k127_3014587_29	234267.Acid_4231	4.813e-43	163.0	COG2332@1|root,COG2332@2|Bacteria,3Y57C@57723|Acidobacteria	57723|Acidobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
LZS3_k127_3014587_7	880070.Cycma_4442	4.376e-150	485.0	28KEJ@1|root,2Z9QB@2|Bacteria,4P1U9@976|Bacteroidetes,47TF2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3014587_12	1340493.JNIF01000003_gene1323	6.274e-109	365.0	COG4105@1|root,COG4105@2|Bacteria,3Y36S@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6,YfiO
LZS3_k127_3014587_38	1340493.JNIF01000003_gene1323	5.181e-17	88.0	COG4105@1|root,COG4105@2|Bacteria,3Y36S@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM Outer membrane assembly lipoprotein YfiO	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6,YfiO
LZS3_k127_3014587_20	639030.JHVA01000001_gene3142	1.489e-81	276.0	COG0036@1|root,COG0036@2|Bacteria,3Y3YN@57723|Acidobacteria,2JIFX@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the ribulose-phosphate 3-epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
LZS3_k127_3014587_18	234267.Acid_3190	3.653e-90	311.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,3Y2NW@57723|Acidobacteria	57723|Acidobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
LZS3_k127_3014587_40	1128421.JAGA01000001_gene2037	1.198e-14	82.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2NRQE@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
LZS3_k127_3014587_36	1244869.H261_16957	2.394e-19	91.0	COG1366@1|root,COG1366@2|Bacteria,1N6U1@1224|Proteobacteria,2UFPK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS3_k127_3014587_16	1267533.KB906745_gene67	1.102e-91	308.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	2|Bacteria	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
LZS3_k127_3014587_15	1267533.KB906745_gene68	1.855e-93	316.0	COG1127@1|root,COG1127@2|Bacteria,3Y45H@57723|Acidobacteria,2JHWI@204432|Acidobacteriia	2|Bacteria	Q	pfam abc	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
LZS3_k127_3014587_35	1499967.BAYZ01000135_gene86	2.639e-20	99.0	COG1463@1|root,COG1463@2|Bacteria,2NQ4Z@2323|unclassified Bacteria	2|Bacteria	Q	MlaD protein	pqiB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009987,GO:0010876,GO:0016043,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044464,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071840,GO:0120009	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
LZS3_k127_3037905_1	649638.Trad_0899	9.779e-206	652.0	COG1249@1|root,COG1249@2|Bacteria,1WI3A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS3_k127_3037905_9	457415.HMPREF1006_02394	5.399e-15	89.0	2BXG3@1|root,2Z82R@2|Bacteria	2|Bacteria	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
LZS3_k127_3037905_8	234267.Acid_4213	8.395e-17	81.0	2DG6A@1|root,2ZUQ0@2|Bacteria,3Y8Y2@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3037905_6	234267.Acid_4214	2.109e-47	173.0	2B6R1@1|root,31ZPU@2|Bacteria,3Y4VP@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3037905_0	1267535.KB906767_gene3187	2.098e-266	853.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,CarbopepD_reg_2,Plug
LZS3_k127_3037905_2	1267535.KB906767_gene2214	2.026e-101	347.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	vioA	GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771	2.6.1.33	ko:K13308,ko:K20429	ko00523,ko01130,map00523,map01130	M00797	R02773	RC00006,RC00781	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_3037905_3	1340493.JNIF01000003_gene3413	1.557e-60	222.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
LZS3_k127_3037905_11	1121472.AQWN01000002_gene2206	0.0006831	50.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,26220@186807|Peptococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS3_k127_3037905_5	1121440.AUMA01000016_gene152	7.331e-54	198.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria,2M9N9@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	epsL	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
LZS3_k127_3037905_10	649831.L083_2812	1.843e-13	83.0	2DQDN@1|root,3365G@2|Bacteria,2H0XJ@201174|Actinobacteria	201174|Actinobacteria	S	O-antigen polysaccharide polymerase Wzy	-	-	-	-	-	-	-	-	-	-	-	-	O-ag_pol_Wzy
LZS3_k127_3037905_7	483219.LILAB_31320	2.493e-40	170.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
LZS3_k127_3043197_0	234267.Acid_5618	8.519e-180	571.0	COG1915@1|root,COG1915@2|Bacteria,3Y6MM@57723|Acidobacteria	57723|Acidobacteria	S	LOR/SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
LZS3_k127_3043197_2	1267535.KB906767_gene30	4.767e-95	320.0	COG0061@1|root,COG0061@2|Bacteria,3Y3E6@57723|Acidobacteria,2JIH5@204432|Acidobacteriia	204432|Acidobacteriia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
LZS3_k127_3043197_3	1123371.ATXH01000012_gene1416	2.804e-79	277.0	COG1189@1|root,COG1189@2|Bacteria,2GGSK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
LZS3_k127_3043197_1	1340493.JNIF01000004_gene102	1.05e-107	356.0	COG0142@1|root,COG0142@2|Bacteria,3Y2HS@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS3_k127_3043197_4	204669.Acid345_3427	1.217e-17	84.0	COG1722@1|root,COG1722@2|Bacteria,3Y5H0@57723|Acidobacteria,2JK24@204432|Acidobacteriia	204432|Acidobacteriia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
LZS3_k127_3048154_4	1340493.JNIF01000003_gene3118	3.595e-51	193.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,Plug,TonB_dep_Rec
LZS3_k127_3048154_3	1210884.HG799468_gene13566	1.62e-108	357.0	COG4221@1|root,COG4221@2|Bacteria,2IYGT@203682|Planctomycetes	203682|Planctomycetes	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_3048154_2	240015.ACP_2642	1.14e-110	385.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,3Y6NA@57723|Acidobacteria,2JKSZ@204432|Acidobacteriia	204432|Acidobacteriia	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
LZS3_k127_3048154_0	234267.Acid_6623	9.114e-262	813.0	COG1032@1|root,COG1032@2|Bacteria,3Y34B@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS3_k127_3048154_1	1267534.KB906755_gene4055	1.324e-172	557.0	COG1032@1|root,COG1032@2|Bacteria,3Y6NQ@57723|Acidobacteria,2JK90@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS3_k127_3061842_2	234267.Acid_1717	2.93e-67	234.0	COG0688@1|root,COG0688@2|Bacteria,3Y4AZ@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
LZS3_k127_3061842_1	234267.Acid_1718	1.641e-78	271.0	COG1183@1|root,COG1183@2|Bacteria,3Y3I7@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
LZS3_k127_3061842_4	1340493.JNIF01000003_gene2302	1.069e-38	151.0	COG2980@1|root,COG2980@2|Bacteria,3Y4V4@57723|Acidobacteria	57723|Acidobacteria	M	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
LZS3_k127_3061842_3	234267.Acid_1721	2.242e-63	230.0	COG1466@1|root,COG1466@2|Bacteria,3Y2XE@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
LZS3_k127_3061842_5	187303.BN69_3666	1.411e-11	68.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria,36YU4@31993|Methylocystaceae	28211|Alphaproteobacteria	J	Ribosomal protein S20	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
LZS3_k127_3061842_0	234267.Acid_2122	3.611e-145	465.0	COG0524@1|root,COG0524@2|Bacteria,3Y6VV@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
LZS3_k127_3064285_0	467661.RKLH11_3282	8.959e-68	254.0	28HYV@1|root,2Z846@2|Bacteria,1MXJ9@1224|Proteobacteria,2UI3G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_313317_5	1235835.C814_01547	3.583e-128	424.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,3WGCZ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	-	-	2.3.3.13,2.3.3.14	ko:K01649,ko:K02594	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R00271,R01213	RC00004,RC00067,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
LZS3_k127_313317_6	1267535.KB906767_gene347	2.586e-106	353.0	COG2159@1|root,COG2159@2|Bacteria,3Y6P0@57723|Acidobacteria	57723|Acidobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_313317_1	1267535.KB906767_gene223	0.0	1030.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_313317_0	1267535.KB906767_gene223	0.0	1032.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_313317_4	1267535.KB906767_gene1184	1.882e-137	461.0	COG0247@1|root,COG0247@2|Bacteria,3Y3K8@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
LZS3_k127_313317_2	935863.AWZR01000001_gene1664	5.992e-160	548.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,1RRUE@1236|Gammaproteobacteria,1X52B@135614|Xanthomonadales	135614|Xanthomonadales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
LZS3_k127_313317_3	171693.BN988_03540	1.407e-139	459.0	COG3119@1|root,COG3119@2|Bacteria,1V6NF@1239|Firmicutes,4ICAZ@91061|Bacilli,23K8G@182709|Oceanobacillus	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_313317_7	269799.Gmet_3291	4.918e-87	293.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,42S4C@68525|delta/epsilon subdivisions,2WNXY@28221|Deltaproteobacteria,43T1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_3146407_0	234267.Acid_7102	5.581e-153	510.0	COG1073@1|root,COG1073@2|Bacteria,3Y6D7@57723|Acidobacteria	57723|Acidobacteria	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
LZS3_k127_3146407_3	1340493.JNIF01000004_gene633	1.1e-10	75.0	COG4386@1|root,COG4386@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Phage_sheath_1,Phage_sheath_1C
LZS3_k127_3146407_2	1459636.NTE_00699	2.877e-108	379.0	COG3391@1|root,arCOG02562@2157|Archaea	2157|Archaea	Q	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,FG-GAP_2
LZS3_k127_3146407_1	204669.Acid345_0099	1.439e-109	363.0	COG0709@1|root,COG0709@2|Bacteria,3Y6V3@57723|Acidobacteria,2JM9D@204432|Acidobacteriia	204432|Acidobacteriia	E	AIR synthase related protein, C-terminal domain	-	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
LZS3_k127_3227006_5	234267.Acid_7436	8.494e-91	312.0	COG2227@1|root,COG3206@1|root,COG2227@2|Bacteria,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K03561,ko:K07011,ko:K20444	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	1.A.30.2.1,4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS3_k127_3227006_3	234267.Acid_5620	7.209e-122	409.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25
LZS3_k127_3227006_6	234267.Acid_1862	1.115e-75	264.0	COG1211@1|root,COG1211@2|Bacteria,3Y3VR@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
LZS3_k127_3227006_2	204669.Acid345_0189	1.785e-137	445.0	COG4956@1|root,COG4956@2|Bacteria,3Y2RT@57723|Acidobacteria,2JKNZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
LZS3_k127_3227006_4	1379698.RBG1_1C00001G0709	1.754e-99	335.0	COG1899@1|root,COG1899@2|Bacteria,2NR8I@2323|unclassified Bacteria	2|Bacteria	O	Deoxyhypusine synthase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
LZS3_k127_3227006_0	234267.Acid_1347	1.963e-292	921.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,3Y3X3@57723|Acidobacteria	57723|Acidobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS3_k127_3227006_1	1340493.JNIF01000003_gene4764	4.835e-279	879.0	arCOG10801@1|root,2Z9IC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3227006_7	864702.OsccyDRAFT_1780	1.8e-13	78.0	COG1409@1|root,COG1409@2|Bacteria,1G1BZ@1117|Cyanobacteria,1H9HQ@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Calcineurin-like phosphoesterase	phoA	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_3278715_0	234267.Acid_5837	1.077e-283	887.0	COG1201@1|root,COG1201@2|Bacteria,3Y348@57723|Acidobacteria	57723|Acidobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
LZS3_k127_3278715_15	1123256.KB907932_gene2950	4.068e-11	72.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1X715@135614|Xanthomonadales	135614|Xanthomonadales	P	subunit of a heme lyase	ccmH1	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
LZS3_k127_3278715_2	1121439.dsat_0488	1.773e-246	767.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,43EW7@68525|delta/epsilon subdivisions,2WM9U@28221|Deltaproteobacteria,2MASI@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3278715_14	234267.Acid_6001	4.588e-12	79.0	COG3055@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4447@2|Bacteria,3Y5BB@57723|Acidobacteria	57723|Acidobacteria	N	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4
LZS3_k127_3278715_11	234267.Acid_3694	1.595e-64	246.0	COG1075@1|root,COG1075@2|Bacteria,3Y8K4@57723|Acidobacteria	57723|Acidobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3278715_7	1122137.AQXF01000003_gene2094	1.516e-141	479.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,2VGDT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS3_k127_3278715_8	926566.Terro_3979	6.563e-90	311.0	COG0520@1|root,COG0520@2|Bacteria,3Y3UN@57723|Acidobacteria,2JK05@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
LZS3_k127_3278715_5	234267.Acid_5690	3e-180	576.0	COG1007@1|root,COG1007@2|Bacteria,3Y43Y@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS3_k127_3278715_3	234267.Acid_5689	4.88e-221	696.0	COG1008@1|root,COG1008@2|Bacteria,3Y3VX@57723|Acidobacteria	57723|Acidobacteria	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS3_k127_3278715_1	234267.Acid_5688	9.958e-267	838.0	COG1009@1|root,COG1009@2|Bacteria,3Y2VS@57723|Acidobacteria	2|Bacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
LZS3_k127_3278715_13	234267.Acid_5687	2.612e-43	162.0	COG0713@1|root,COG0713@2|Bacteria,3Y54E@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
LZS3_k127_3278715_12	234267.Acid_5686	1.369e-45	171.0	COG0839@1|root,COG0839@2|Bacteria,3Y5QU@57723|Acidobacteria	57723|Acidobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
LZS3_k127_3278715_9	234267.Acid_5685	1.836e-75	255.0	COG1143@1|root,COG1143@2|Bacteria,3Y529@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
LZS3_k127_3278715_6	234267.Acid_5691	9.498e-152	490.0	COG1005@1|root,COG1005@2|Bacteria,3Y3XZ@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS3_k127_3278715_4	234267.Acid_5684	2.82e-206	645.0	COG0649@1|root,COG0649@2|Bacteria,3Y3AB@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
LZS3_k127_3278715_10	234267.Acid_5683	1.83e-69	240.0	COG0852@1|root,COG0852@2|Bacteria,3Y5E8@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
LZS3_k127_3287338_8	379066.GAU_0007	6.712e-41	159.0	COG0461@1|root,COG0461@2|Bacteria,1ZTMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS3_k127_3287338_2	1121468.AUBR01000014_gene2225	6.75e-108	360.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42EK5@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
LZS3_k127_3287338_0	1267535.KB906767_gene3553	1.494e-175	557.0	COG0045@1|root,COG0045@2|Bacteria,3Y36X@57723|Acidobacteria,2JHR1@204432|Acidobacteriia	204432|Acidobacteriia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
LZS3_k127_3287338_1	264462.Bd3811	1.181e-125	408.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2MSQU@213481|Bdellovibrionales,2WJBV@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
LZS3_k127_3287338_7	234267.Acid_3376	1.068e-46	185.0	COG0105@1|root,COG0105@2|Bacteria,3Y4MW@57723|Acidobacteria	57723|Acidobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
LZS3_k127_3287338_11	522373.Smlt3111	4.346e-05	49.0	2EAVJ@1|root,334WZ@2|Bacteria,1NEMG@1224|Proteobacteria,1ST2E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3287338_9	224325.AF_0635	6.691e-24	114.0	COG2358@1|root,arCOG01801@2157|Archaea,2XTR3@28890|Euryarchaeota,246YE@183980|Archaeoglobi	183980|Archaeoglobi	S	TRAP transporter solute receptor, TAXI family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
LZS3_k127_3287338_6	330084.JNYZ01000038_gene4138	9.263e-53	196.0	COG1809@1|root,COG1809@2|Bacteria	2|Bacteria	S	phosphosulfolactate synthase activity	comA	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
LZS3_k127_3287338_4	234267.Acid_5911	1.07e-78	269.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,3Y519@57723|Acidobacteria	57723|Acidobacteria	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
LZS3_k127_3287338_5	1340493.JNIF01000003_gene4084	2.073e-73	261.0	COG2304@1|root,COG2304@2|Bacteria,3Y38P@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
LZS3_k127_3287338_10	204669.Acid345_2059	5.313e-14	75.0	COG1923@1|root,COG1923@2|Bacteria,3Y5PK@57723|Acidobacteria,2JJYT@204432|Acidobacteriia	204432|Acidobacteriia	S	Hfq protein	-	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
LZS3_k127_3287338_3	234267.Acid_5909	1.047e-102	341.0	COG0483@1|root,COG0483@2|Bacteria,3Y3GD@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
LZS3_k127_3301289_25	400682.PAC_15728068	1.043e-06	57.0	COG4948@1|root,2QRKX@2759|Eukaryota,38HCT@33154|Opisthokonta,3BYW6@33208|Metazoa	33208|Metazoa	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_3301289_4	234267.Acid_1856	1.174e-156	512.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y45M@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,SpoIIE
LZS3_k127_3301289_17	1267535.KB906767_gene2420	4.512e-60	212.0	COG0735@1|root,COG0735@2|Bacteria,3Y5IN@57723|Acidobacteria	57723|Acidobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS3_k127_3301289_3	1267535.KB906767_gene2657	5.409e-157	502.0	COG1088@1|root,COG1088@2|Bacteria,3Y3E7@57723|Acidobacteria,2JIRI@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS3_k127_3301289_13	234267.Acid_6227	3.39e-74	254.0	COG1898@1|root,COG1898@2|Bacteria,3Y5V0@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
LZS3_k127_3301289_14	234267.Acid_0601	4.087e-70	249.0	COG1912@1|root,COG1912@2|Bacteria,3Y50E@57723|Acidobacteria	57723|Acidobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
LZS3_k127_3301289_6	234267.Acid_0600	1.499e-142	462.0	COG1104@1|root,COG1104@2|Bacteria,3Y389@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS3_k127_3301289_2	1267535.KB906767_gene1561	3.823e-159	509.0	COG0482@1|root,COG0482@2|Bacteria,3Y2JX@57723|Acidobacteria,2JHKV@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
LZS3_k127_3301289_10	234267.Acid_7928	1.467e-85	299.0	COG1064@1|root,COG1064@2|Bacteria,3Y3X1@57723|Acidobacteria	57723|Acidobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_3301289_19	1340493.JNIF01000003_gene2101	2.407e-48	184.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	CMAS,MTS,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS3_k127_3301289_8	1267535.KB906767_gene365	7.758e-123	406.0	COG2017@1|root,COG2017@2|Bacteria,3Y4YM@57723|Acidobacteria	57723|Acidobacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3301289_16	1340493.JNIF01000004_gene910	4.831e-64	231.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS3_k127_3301289_1	234267.Acid_7871	1.395e-166	541.0	COG0616@1|root,COG0616@2|Bacteria,3Y3M1@57723|Acidobacteria	57723|Acidobacteria	OU	PFAM peptidase S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS3_k127_3301289_7	1267535.KB906767_gene3338	8.147e-131	431.0	COG1446@1|root,COG1446@2|Bacteria,3Y2Y8@57723|Acidobacteria,2JIW3@204432|Acidobacteriia	204432|Acidobacteriia	E	Asparaginase	-	-	3.5.1.26	ko:K01444	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Asparaginase_2
LZS3_k127_3301289_5	1122137.AQXF01000003_gene2094	2.192e-152	511.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,2VGDT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS3_k127_3301289_23	338963.Pcar_1382	5.114e-09	58.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
LZS3_k127_3301289_12	243233.MCA1427	8.839e-77	269.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2
LZS3_k127_3301289_11	768671.ThimaDRAFT_3236	5.703e-77	270.0	COG1215@1|root,COG1215@2|Bacteria,1QUG1@1224|Proteobacteria,1RZH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_3301289_26	1112214.AHIS01000101_gene1663	4.049e-05	55.0	COG1807@1|root,COG1807@2|Bacteria,1RM6R@1224|Proteobacteria,2USPP@28211|Alphaproteobacteria,2K8AC@204457|Sphingomonadales	204457|Sphingomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_3301289_24	1307759.JOMJ01000004_gene2508	3.742e-08	61.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria,42XKF@68525|delta/epsilon subdivisions,2WT6J@28221|Deltaproteobacteria,2M8UX@213115|Desulfovibrionales	28221|Deltaproteobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
LZS3_k127_3301289_18	1380355.JNIJ01000052_gene2180	4.008e-54	207.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,2U2KK@28211|Alphaproteobacteria,3K1BY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	lgtF	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_3301289_20	882083.SacmaDRAFT_1146	4.941e-47	173.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria,4E4MC@85010|Pseudonocardiales	201174|Actinobacteria	S	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_3301289_21	306281.AJLK01000110_gene2680	1.549e-44	173.0	COG5637@1|root,COG5637@2|Bacteria,1G2FS@1117|Cyanobacteria,1JI0E@1189|Stigonemataceae	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Polyketide_cyc
LZS3_k127_3301289_9	592015.HMPREF1705_00495	1.341e-112	369.0	COG0428@1|root,COG0428@2|Bacteria,3T9UW@508458|Synergistetes	508458|Synergistetes	P	PFAM zinc iron permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
LZS3_k127_3301289_0	518766.Rmar_0629	3.123e-224	732.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
LZS3_k127_3301289_15	1267535.KB906767_gene98	1.295e-69	244.0	COG0265@1|root,COG0265@2|Bacteria,3Y2WB@57723|Acidobacteria,2JI8Y@204432|Acidobacteriia	204432|Acidobacteriia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_3302993_5	497964.CfE428DRAFT_4770	3.115e-58	220.0	COG3119@1|root,COG3119@2|Bacteria,46UNC@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_3302993_1	1123248.KB893325_gene1154	3.847e-190	612.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	2|Bacteria	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
LZS3_k127_3302993_7	926566.Terro_4138	5.152e-44	167.0	COG3303@1|root,COG3303@2|Bacteria,3Y7PT@57723|Acidobacteria,2JMPS@204432|Acidobacteriia	204432|Acidobacteriia	P	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
LZS3_k127_3302993_0	316056.RPC_1039	1.131e-238	749.0	COG3177@1|root,COG3177@2|Bacteria,1MVW0@1224|Proteobacteria,2TU9A@28211|Alphaproteobacteria,3JV8G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
LZS3_k127_3302993_6	234267.Acid_3573	2.627e-54	204.0	COG0457@1|root,COG0457@2|Bacteria,3Y3JH@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS3_k127_3302993_8	1267535.KB906767_gene1512	1.409e-30	129.0	COG0500@1|root,COG0500@2|Bacteria,3Y5HU@57723|Acidobacteria	57723|Acidobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3302993_9	234267.Acid_1037	8.475e-30	126.0	COG1664@1|root,COG1664@2|Bacteria,3Y49V@57723|Acidobacteria	57723|Acidobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS3_k127_3302993_10	1123405.AUMM01000032_gene1763	3.423e-24	109.0	COG0494@1|root,COG0494@2|Bacteria,1V9FI@1239|Firmicutes,4HJ1A@91061|Bacilli	91061|Bacilli	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
LZS3_k127_3302993_3	1254432.SCE1572_34750	6.559e-99	340.0	COG3866@1|root,COG3866@2|Bacteria,1MUT3@1224|Proteobacteria,42S47@68525|delta/epsilon subdivisions,2WND1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
LZS3_k127_3302993_12	401053.AciPR4_3976	1.345e-05	52.0	COG2010@1|root,COG2010@2|Bacteria,3Y5PY@57723|Acidobacteria,2JJWQ@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS3_k127_3302993_2	234267.Acid_1914	3.498e-189	600.0	COG0304@1|root,COG0304@2|Bacteria,3Y43C@57723|Acidobacteria	57723|Acidobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_3302993_4	118173.KB235914_gene2353	1.182e-68	241.0	COG1732@1|root,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria,1H9PY@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
LZS3_k127_3306354_0	204669.Acid345_4736	3.167e-283	883.0	COG0441@1|root,COG0441@2|Bacteria,3Y2V0@57723|Acidobacteria,2JHV7@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
LZS3_k127_3306354_4	234267.Acid_4787	7.891e-25	109.0	COG2331@1|root,COG2331@2|Bacteria,3Y5KN@57723|Acidobacteria	57723|Acidobacteria	S	Regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
LZS3_k127_3306354_2	240015.ACP_0435	6.565e-177	593.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria,2JMKF@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_3306354_5	234267.Acid_0101	2.199e-19	92.0	2C5W1@1|root,2ZWMD@2|Bacteria,3Y8VN@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3306354_3	65393.PCC7424_1030	1.941e-77	267.0	COG3217@1|root,COG3217@2|Bacteria,1G15T@1117|Cyanobacteria,3KG3D@43988|Cyanothece	1117|Cyanobacteria	S	MOSC domain protein beta barrel domain protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
LZS3_k127_3306354_7	234267.Acid_0129	4.025e-11	69.0	COG0745@1|root,COG0745@2|Bacteria	234267.Acid_0129|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3306354_1	1267535.KB906767_gene2722	9.711e-210	665.0	COG0138@1|root,COG0138@2|Bacteria,3Y2QI@57723|Acidobacteria,2JHSU@204432|Acidobacteriia	204432|Acidobacteriia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
LZS3_k127_3306584_10	1449350.OCH239_15655	1.63e-21	102.0	COG1215@1|root,COG1215@2|Bacteria,1RIJ7@1224|Proteobacteria,2U1KG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase, family 2	exoU	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_3306584_8	1280948.HY36_14660	2.321e-59	218.0	COG1215@1|root,COG1215@2|Bacteria,1R4P3@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS3_k127_3306584_1	1267535.KB906767_gene1051	4.035e-106	354.0	COG1533@1|root,COG1533@2|Bacteria	2|Bacteria	L	DNA photolyase activity	M1-769	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS3_k127_3306584_7	234267.Acid_2835	1.994e-62	225.0	COG1322@1|root,COG1322@2|Bacteria,3Y3JC@57723|Acidobacteria	57723|Acidobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3306584_11	1077285.AGDG01000039_gene4081	6.994e-17	83.0	COG1983@1|root,COG1983@2|Bacteria,4NX1N@976|Bacteroidetes,2FUW2@200643|Bacteroidia,4ARR3@815|Bacteroidaceae	976|Bacteroidetes	KT	PspC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PspC
LZS3_k127_3306584_2	1340493.JNIF01000003_gene3778	1.443e-96	329.0	2DBN7@1|root,2ZA2Y@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
LZS3_k127_3306584_6	1267535.KB906767_gene293	5.281e-74	267.0	COG1921@1|root,COG1921@2|Bacteria,3Y2SF@57723|Acidobacteria,2JKWG@204432|Acidobacteriia	204432|Acidobacteriia	E	L-seryl-tRNASec selenium transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3306584_4	234267.Acid_7863	1.272e-80	278.0	COG0179@1|root,COG0179@2|Bacteria,3Y30T@57723|Acidobacteria	57723|Acidobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
LZS3_k127_3306584_3	234267.Acid_7863	9.819e-91	307.0	COG0179@1|root,COG0179@2|Bacteria,3Y30T@57723|Acidobacteria	57723|Acidobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
LZS3_k127_3306584_0	1340493.JNIF01000003_gene2092	1.946e-209	664.0	COG2303@1|root,COG2303@2|Bacteria,3Y41Y@57723|Acidobacteria	2|Bacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
LZS3_k127_3306584_9	309807.SRU_2528	3.221e-38	151.0	2CISN@1|root,2Z7MB@2|Bacteria,4NFJX@976|Bacteroidetes,1FJQ0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
LZS3_k127_3306584_5	1267535.KB906767_gene2426	1.828e-76	259.0	COG0696@1|root,COG0696@2|Bacteria,3Y2YH@57723|Acidobacteria,2JIZ0@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
LZS3_k127_3308625_18	1336243.JAEA01000003_gene2476	1.179e-52	188.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria,1JUR8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
LZS3_k127_3308625_23	401053.AciPR4_1484	1.254e-27	126.0	COG2304@1|root,COG2304@2|Bacteria,3Y3QQ@57723|Acidobacteria,2JHV1@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
LZS3_k127_3308625_12	710685.MycrhN_5567	5.727e-73	264.0	COG1414@1|root,COG1414@2|Bacteria,2I3CC@201174|Actinobacteria,2337H@1762|Mycobacteriaceae	201174|Actinobacteria	K	PFAM O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
LZS3_k127_3308625_25	352165.HMPREF7215_1840	2.138e-21	99.0	COG0251@1|root,COG0251@2|Bacteria,3TBCD@508458|Synergistetes	508458|Synergistetes	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS3_k127_3308625_28	1280946.HY29_15175	2.15e-08	67.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria,43WYB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8
LZS3_k127_3308625_4	987059.RBXJA2T_01380	3.442e-139	455.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2VK83@28216|Betaproteobacteria,1KMBQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	hmsR	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
LZS3_k127_3308625_30	1300345.LF41_2603	8.485e-06	55.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1X3E5@135614|Xanthomonadales	135614|Xanthomonadales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
LZS3_k127_3308625_21	211586.SO_3775	2.521e-32	135.0	arCOG07807@1|root,32S82@2|Bacteria,1RDIN@1224|Proteobacteria,1SDFY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
LZS3_k127_3308625_0	234267.Acid_1922	2.548e-191	610.0	COG2204@1|root,COG2204@2|Bacteria,3Y38J@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_3308625_9	234267.Acid_1921	6.072e-89	308.0	COG3852@1|root,COG3852@2|Bacteria,3Y9A1@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_3308625_14	880072.Desac_0526	1.139e-67	237.0	2BC31@1|root,325MS@2|Bacteria,1NBYV@1224|Proteobacteria,431MW@68525|delta/epsilon subdivisions,2WWTC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3308625_22	1340493.JNIF01000004_gene946	8.258e-30	126.0	COG0637@1|root,COG0637@2|Bacteria,3Y49E@57723|Acidobacteria	57723|Acidobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS3_k127_3308625_15	1123242.JH636435_gene2790	3.175e-58	212.0	COG3828@1|root,COG3828@2|Bacteria,2IZ1Z@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_3308625_3	234267.Acid_5573	7.916e-142	455.0	COG0115@1|root,COG0115@2|Bacteria,3Y32X@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS3_k127_3308625_24	1340493.JNIF01000004_gene670	4.203e-24	120.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_2,Calx-beta,Laminin_G_3,PA14,VPEP
LZS3_k127_3308625_17	1210884.HG799462_gene7850	3.182e-54	200.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pcaD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
LZS3_k127_3308625_6	1340493.JNIF01000004_gene942	6.673e-124	407.0	COG1820@1|root,COG1820@2|Bacteria,3Y3NQ@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
LZS3_k127_3308625_11	1121448.DGI_1524	2.863e-77	289.0	COG3291@1|root,COG3291@2|Bacteria,1PHGX@1224|Proteobacteria,437VV@68525|delta/epsilon subdivisions,2X1BB@28221|Deltaproteobacteria,2MEPR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_5
LZS3_k127_3308625_13	234267.Acid_0627	1.196e-71	272.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHU_C,Cadherin-like,ChW,F5_F8_type_C,fn3
LZS3_k127_3308625_10	886293.Sinac_2845	2.698e-80	280.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
LZS3_k127_3308625_8	886293.Sinac_5380	2.69e-97	332.0	28PTH@1|root,2ZCER@2|Bacteria,2IZHG@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3308625_5	234267.Acid_2729	7.369e-130	425.0	28K3C@1|root,2Z9SH@2|Bacteria,3Y7UF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3308625_16	1340493.JNIF01000003_gene2086	8.431e-58	211.0	2CMWR@1|root,32SFR@2|Bacteria,3Y7WI@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3308625_20	926566.Terro_0373	1.733e-40	157.0	COG1595@1|root,COG1595@2|Bacteria,3Y59D@57723|Acidobacteria,2JNBN@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_3308625_1	1267535.KB906767_gene1057	1.261e-178	587.0	COG1629@1|root,COG4771@2|Bacteria,3Y36N@57723|Acidobacteria,2JI4W@204432|Acidobacteriia	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_3308625_7	234267.Acid_7358	9.358e-106	348.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria	57723|Acidobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100,4.2.1.17	ko:K01715,ko:K07537	ko00362,ko00650,ko01100,ko01120,ko01200,ko01220,map00362,map00650,map01100,map01120,map01200,map01220	M00541	R03026,R05597	RC00831,RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_3308625_19	234267.Acid_0308	1.533e-46	171.0	COG3118@1|root,COG3118@2|Bacteria,3Y53D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS3_k127_3308625_2	204669.Acid345_3349	4.766e-167	538.0	COG0297@1|root,COG0297@2|Bacteria,3Y3IH@57723|Acidobacteria,2JHNU@204432|Acidobacteriia	204432|Acidobacteriia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
LZS3_k127_3326727_1	671143.DAMO_2373	1.198e-163	527.0	COG1012@1|root,COG1012@2|Bacteria,2NNW6@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_3326727_0	215803.DB30_6435	6.944e-262	833.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,437F0@68525|delta/epsilon subdivisions,2XA2R@28221|Deltaproteobacteria,2YTSS@29|Myxococcales	28221|Deltaproteobacteria	E	ERAP1-like C-terminal domain	-	-	3.4.11.14	ko:K01263	-	-	-	-	ko00000,ko01000	-	-	-	ERAP1_C,Peptidase_M1
LZS3_k127_3326727_2	344747.PM8797T_12598	1.877e-90	303.0	COG0684@1|root,COG0684@2|Bacteria,2IYU5@203682|Planctomycetes	203682|Planctomycetes	H	Demethylmenaquinone methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
LZS3_k127_3326727_6	204669.Acid345_1709	8.527e-32	141.0	COG0491@1|root,COG0491@2|Bacteria,3Y4D7@57723|Acidobacteria,2JKB5@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_3326727_3	98439.AJLL01000100_gene502	2.087e-67	233.0	COG1839@1|root,COG1839@2|Bacteria,1G575@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
LZS3_k127_3326727_4	316274.Haur_1472	3.112e-53	209.0	COG5617@1|root,COG5617@2|Bacteria,2GAHU@200795|Chloroflexi,3767W@32061|Chloroflexia	32061|Chloroflexia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3326727_5	1094980.Mpsy_2844	5.764e-32	130.0	arCOG03338@1|root,arCOG03338@2157|Archaea,2XXKV@28890|Euryarchaeota,2NA0P@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3329236_12	234267.Acid_7349	1.146e-64	227.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS3_k127_3329236_4	234267.Acid_0746	2.586e-169	581.0	COG2911@1|root,COG2911@2|Bacteria,3Y3A6@57723|Acidobacteria	57723|Acidobacteria	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
LZS3_k127_3329236_20	234267.Acid_0747	6.636e-22	105.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	nifM	-	2.3.1.39,5.2.1.8	ko:K00645,ko:K01802,ko:K02597,ko:K03769,ko:K03770,ko:K03771	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS3_k127_3329236_1	234267.Acid_0748	1.997e-238	769.0	COG4775@1|root,COG4775@2|Bacteria,3Y2RF@57723|Acidobacteria	57723|Acidobacteria	M	Surface antigen variable number	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
LZS3_k127_3329236_7	1267535.KB906767_gene879	5.422e-161	524.0	COG0612@1|root,COG0612@2|Bacteria,3Y3XF@57723|Acidobacteria,2JHR4@204432|Acidobacteriia	204432|Acidobacteriia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_3329236_3	1267535.KB906767_gene880	3.232e-181	594.0	COG0612@1|root,COG0612@2|Bacteria,3Y2FB@57723|Acidobacteria,2JHWY@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
LZS3_k127_3329236_16	472759.Nhal_1657	1.997e-29	122.0	COG4097@1|root,COG4097@2|Bacteria	2|Bacteria	P	nitric oxide dioxygenase activity	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_8,Ferric_reduct,NAD_binding_1
LZS3_k127_3329236_9	1340493.JNIF01000004_gene523	8.984e-130	432.0	COG0265@1|root,COG0265@2|Bacteria,3Y2SD@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_3329236_15	671143.DAMO_0611	3.834e-32	141.0	COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
LZS3_k127_3329236_2	204669.Acid345_2904	1.343e-184	593.0	COG1215@1|root,COG1215@2|Bacteria,3Y31I@57723|Acidobacteria,2JIKW@204432|Acidobacteriia	204432|Acidobacteriia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
LZS3_k127_3329236_24	234267.Acid_1396	7.76e-06	55.0	2FE1U@1|root,34620@2|Bacteria,3Y8MC@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3329236_23	1397696.KK211189_gene2233	7.749e-08	61.0	COG1514@1|root,COG1514@2|Bacteria,1V2F3@1239|Firmicutes,4HG6P@91061|Bacilli	91061|Bacilli	J	Belongs to the 2H phosphoesterase superfamily. YjcG family	yjcG	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
LZS3_k127_3329236_10	1340493.JNIF01000003_gene2431	9.644e-95	330.0	COG1524@1|root,COG1524@2|Bacteria,3Y4MJ@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_3329236_19	926566.Terro_1010	6.801e-23	105.0	2EA3B@1|root,3348D@2|Bacteria,3Y5J1@57723|Acidobacteria,2JJZE@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3329236_6	1267535.KB906767_gene108	2.273e-165	536.0	COG0617@1|root,COG0617@2|Bacteria,3Y3B8@57723|Acidobacteria,2JIIS@204432|Acidobacteriia	204432|Acidobacteriia	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
LZS3_k127_3329236_0	215803.DB30_4063	1.548e-240	755.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS3_k127_3329236_5	234267.Acid_0850	7.225e-168	537.0	COG0389@1|root,COG0389@2|Bacteria,3Y3NY@57723|Acidobacteria	57723|Acidobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
LZS3_k127_3329236_17	502025.Hoch_2238	3.705e-27	114.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,2YVHC@29|Myxococcales	28221|Deltaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
LZS3_k127_3329236_14	240015.ACP_2746	2.426e-36	138.0	COG0211@1|root,COG0211@2|Bacteria,3Y5D8@57723|Acidobacteria,2JJPG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
LZS3_k127_3329236_8	234267.Acid_3160	1.688e-146	472.0	COG0536@1|root,COG0536@2|Bacteria,3Y2J7@57723|Acidobacteria	57723|Acidobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
LZS3_k127_3329236_13	1267535.KB906767_gene4537	1.916e-48	181.0	COG0328@1|root,COG1057@1|root,COG0328@2|Bacteria,COG1057@2|Bacteria,3Y5D2@57723|Acidobacteria,2JJNT@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS3_k127_3329236_18	1267535.KB906767_gene3901	1.254e-26	123.0	2DYK5@1|root,34A5U@2|Bacteria,3Y8GF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
LZS3_k127_3329236_11	234267.Acid_3334	8.292e-65	239.0	COG3391@1|root,COG3391@2|Bacteria,3Y3R3@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
LZS3_k127_3329236_21	886293.Sinac_0608	1.302e-09	63.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NB-ARC,cNMP_binding
LZS3_k127_3366002_2	237368.SCABRO_01554	1.694e-69	251.0	COG1538@1|root,COG1538@2|Bacteria,2IZPU@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_3366002_1	335543.Sfum_2436	2.013e-101	349.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2MRTA@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
LZS3_k127_3366002_0	246197.MXAN_0988	3.29e-309	968.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
LZS3_k127_3377873_7	123899.JPQP01000004_gene528	1.911e-111	366.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2VM24@28216|Betaproteobacteria,3T1BF@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Ectoine hydroxylase	thpD	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
LZS3_k127_3377873_19	338963.Pcar_3027	1.519e-08	64.0	COG2095@1|root,COG2095@2|Bacteria	2|Bacteria	U	MarC family integral membrane protein	yhgN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
LZS3_k127_3377873_2	314345.SPV1_04443	1.739e-164	531.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
LZS3_k127_3377873_5	1267535.KB906767_gene4240	1.493e-115	394.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Trans_reg_C
LZS3_k127_3377873_18	234267.Acid_2463	1.758e-12	78.0	COG2133@1|root,COG2133@2|Bacteria,3Y81J@57723|Acidobacteria	57723|Acidobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_3377873_10	1379698.RBG1_1C00001G1616	9.596e-84	308.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS3_k127_3377873_14	247490.KSU1_C1644	6.523e-70	243.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS3_k127_3377873_9	1379698.RBG1_1C00001G1616	1.282e-91	314.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS3_k127_3377873_4	869210.Marky_0500	1.17e-118	408.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_3377873_15	234267.Acid_2879	6.949e-41	173.0	COG4386@1|root,COG4386@2|Bacteria,3Y76B@57723|Acidobacteria	57723|Acidobacteria	S	tail sheath protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3377873_1	886293.Sinac_6965	3.273e-189	605.0	COG0739@1|root,COG1506@1|root,COG3291@1|root,COG0739@2|Bacteria,COG1506@2|Bacteria,COG3291@2|Bacteria,2IYE5@203682|Planctomycetes	203682|Planctomycetes	E	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
LZS3_k127_3377873_3	1267535.KB906767_gene5243	3.743e-159	515.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_3377873_6	118168.MC7420_6398	3.631e-115	379.0	COG4301@1|root,COG4301@2|Bacteria,1G2JI@1117|Cyanobacteria,1H739@1150|Oscillatoriales	1117|Cyanobacteria	S	conserved protein (DUF2260)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
LZS3_k127_3377873_0	1487953.JMKF01000036_gene3253	1.271e-193	612.0	COG1262@1|root,COG1262@2|Bacteria,1G0FF@1117|Cyanobacteria,1H8UZ@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
LZS3_k127_3377873_16	1267535.KB906767_gene4647	4.707e-40	162.0	COG4449@1|root,COG4449@2|Bacteria,3Y84G@57723|Acidobacteria	57723|Acidobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
LZS3_k127_3377873_11	234267.Acid_0555	2.894e-77	266.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
LZS3_k127_3377873_13	1150399.AQYK01000001_gene1084	1.055e-71	251.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4FKZ2@85023|Microbacteriaceae	201174|Actinobacteria	GM	ATPases associated with a variety of cellular activities	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
LZS3_k127_3377873_17	1267535.KB906767_gene4421	1.939e-20	96.0	2EN0M@1|root,33FNU@2|Bacteria,3Y60X@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3377873_8	234267.Acid_6703	5.449e-96	320.0	COG0176@1|root,COG0176@2|Bacteria,3Y4BN@57723|Acidobacteria	57723|Acidobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
LZS3_k127_3377873_21	1454007.JAUG01000002_gene2905	0.0008264	43.0	COG1649@1|root,COG1649@2|Bacteria,4NFKQ@976|Bacteroidetes,1IP9B@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
LZS3_k127_3391160_23	32057.KB217478_gene7346	2.978e-19	101.0	COG5652@1|root,COG5652@2|Bacteria,1GC2R@1117|Cyanobacteria,1HM2P@1161|Nostocales	1117|Cyanobacteria	S	PFAM VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
LZS3_k127_3391160_8	234267.Acid_4658	8.043e-136	448.0	COG0472@1|root,COG0472@2|Bacteria,3Y5GB@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
LZS3_k127_3391160_12	706587.Desti_4570	2.239e-88	304.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,42PIY@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyltransferase like family 2	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS3_k127_3391160_14	1223410.KN050846_gene2771	7.113e-74	263.0	COG0438@1|root,COG0438@2|Bacteria,4NHHN@976|Bacteroidetes,1HZQ0@117743|Flavobacteriia	976|Bacteroidetes	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_3391160_3	1267535.KB906767_gene2208	3.783e-163	541.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,3Y2V7@57723|Acidobacteria,2JIYH@204432|Acidobacteriia	204432|Acidobacteriia	D	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,GNVR
LZS3_k127_3391160_15	1267535.KB906767_gene2207	5.381e-71	253.0	COG1596@1|root,COG1596@2|Bacteria,3Y57H@57723|Acidobacteria,2JJNS@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
LZS3_k127_3391160_24	1041522.MCOL_V203750	2.018e-14	83.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,234XR@1762|Mycobacteriaceae	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_3391160_7	344747.PM8797T_25641	2.267e-144	473.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
LZS3_k127_3391160_18	234267.Acid_2904	1.072e-53	208.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
LZS3_k127_3391160_6	314230.DSM3645_08512	8.978e-157	504.0	COG2170@1|root,COG2170@2|Bacteria,2IXAU@203682|Planctomycetes	203682|Planctomycetes	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
LZS3_k127_3391160_10	314230.DSM3645_08507	2.813e-117	391.0	COG1473@1|root,COG1473@2|Bacteria,2IY78@203682|Planctomycetes	203682|Planctomycetes	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_3391160_26	292459.STH1297	4.957e-07	57.0	COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,24B59@186801|Clostridia	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
LZS3_k127_3391160_22	1173024.KI912149_gene5584	3.122e-21	96.0	2DRDY@1|root,33BC0@2|Bacteria,1G9R7@1117|Cyanobacteria,1JMI1@1189|Stigonemataceae	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
LZS3_k127_3391160_19	1121939.L861_02695	1.471e-43	173.0	COG1493@1|root,COG1493@2|Bacteria,1NN8Y@1224|Proteobacteria,1SGEG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3391160_9	1121939.L861_02680	1.767e-119	407.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.3.6,6.3.5.4	ko:K01953,ko:K18316	ko00250,ko00332,ko01100,ko01110,ko01130,ko02024,map00250,map00332,map01100,map01110,map01130,map02024	M00675	R00578,R10556	RC00010,RC03195	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Asn_synthase,DUF1933,GATase_7
LZS3_k127_3391160_27	397291.C804_00531	0.0005623	44.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_24,TylF
LZS3_k127_3391160_4	42256.RradSPS_0959	1.102e-161	521.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,4CPHW@84995|Rubrobacteria	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
LZS3_k127_3391160_2	143224.JQMD01000002_gene1596	1.358e-165	536.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1HZA1@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_3391160_20	861299.J421_0777	3.049e-28	119.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
LZS3_k127_3391160_13	1296416.JACB01000027_gene4076	1.231e-87	299.0	2BWKA@1|root,32QZQ@2|Bacteria,4P163@976|Bacteroidetes,1I86M@117743|Flavobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
LZS3_k127_3391160_1	234267.Acid_6537	7.042e-179	582.0	COG1073@1|root,COG1073@2|Bacteria,3Y6M5@57723|Acidobacteria	57723|Acidobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3391160_5	880070.Cycma_3618	3.736e-158	526.0	arCOG10801@1|root,2Z9IC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3391160_16	1521187.JPIM01000188_gene1946	2.13e-69	249.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi,3767C@32061|Chloroflexia	32061|Chloroflexia	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3391160_17	234267.Acid_1271	4.575e-65	243.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS3_k127_3391160_0	497964.CfE428DRAFT_5247	2.53e-237	767.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
LZS3_k127_3420416_0	1123514.KB905900_gene2162	0.0	1075.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales	72273|Thiotrichales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
LZS3_k127_3420416_32	240016.ABIZ01000001_gene5379	0.0003641	43.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	cadA	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hemerythrin,Hydrolase
LZS3_k127_3420416_2	266779.Meso_2458	4.849e-236	745.0	COG0500@1|root,COG2267@1|root,COG2226@2|Bacteria,COG2267@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
LZS3_k127_3420416_4	404589.Anae109_3668	1.938e-230	724.0	COG2197@1|root,COG2197@2|Bacteria,1R03J@1224|Proteobacteria	1224|Proteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
LZS3_k127_3420416_16	926566.Terro_2385	2.773e-100	341.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria,2JKDV@204432|Acidobacteriia	204432|Acidobacteriia	S	amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
LZS3_k127_3420416_10	1267535.KB906767_gene2122	2.824e-122	401.0	COG2171@1|root,COG2171@2|Bacteria,3Y2Z3@57723|Acidobacteria,2JIDV@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the transferase hexapeptide repeat family	-	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep_2,THDPS_N_2
LZS3_k127_3420416_29	1123073.KB899241_gene2458	4.089e-16	80.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,1SSZE@1236|Gammaproteobacteria,1X8JS@135614|Xanthomonadales	135614|Xanthomonadales	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
LZS3_k127_3420416_19	234267.Acid_5587	1.347e-80	290.0	28NCT@1|root,2ZBFR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3420416_25	234267.Acid_1195	1.626e-35	145.0	COG1437@1|root,COG1437@2|Bacteria,3Y4V3@57723|Acidobacteria	57723|Acidobacteria	F	CYTH	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
LZS3_k127_3420416_12	234267.Acid_3351	2.722e-120	396.0	COG0142@1|root,COG0142@2|Bacteria,3Y2VJ@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS3_k127_3420416_18	1340493.JNIF01000003_gene3781	2.31e-81	281.0	COG0084@1|root,COG0084@2|Bacteria,3Y4DK@57723|Acidobacteria	57723|Acidobacteria	L	Hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
LZS3_k127_3420416_1	234267.Acid_3353	6.656e-264	829.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3Y2I2@57723|Acidobacteria	57723|Acidobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
LZS3_k127_3420416_11	1267535.KB906767_gene5356	1.862e-121	402.0	COG1641@1|root,COG1641@2|Bacteria,3Y42R@57723|Acidobacteria,2JI6G@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function DUF111	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
LZS3_k127_3420416_15	1123070.KB899268_gene2418	1.556e-100	344.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA,VCBS
LZS3_k127_3420416_9	460265.Mnod_2965	1.143e-142	462.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TUT7@28211|Alphaproteobacteria,1JSXA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM 2-nitropropane dioxygenase NPD	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
LZS3_k127_3420416_14	234267.Acid_4908	9.326e-102	341.0	COG0673@1|root,COG0673@2|Bacteria,3Y6XR@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_3420416_17	1340493.JNIF01000004_gene113	2.768e-91	310.0	COG1082@1|root,COG1082@2|Bacteria,3Y6ZI@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_3420416_28	309801.trd_1920	3.905e-16	90.0	COG5624@1|root,COG5624@2|Bacteria,2G94N@200795|Chloroflexi	200795|Chloroflexi	K	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3420416_22	330214.NIDE4060	2.959e-45	189.0	COG1858@1|root,COG1858@2|Bacteria,3J0GH@40117|Nitrospirae	40117|Nitrospirae	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS3_k127_3420416_20	234267.Acid_2904	3.329e-51	209.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
LZS3_k127_3420416_27	234267.Acid_5579	1.26e-23	106.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
LZS3_k127_3420416_26	396588.Tgr7_2522	3.875e-32	135.0	COG1320@1|root,COG1320@2|Bacteria,1RH17@1224|Proteobacteria,1S8X0@1236|Gammaproteobacteria,1WZ0J@135613|Chromatiales	135613|Chromatiales	P	Na+/H+ antiporter subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
LZS3_k127_3420416_30	768066.HELO_3508	1.603e-15	80.0	COG2212@1|root,COG2212@2|Bacteria,1N7BC@1224|Proteobacteria,1SE0C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Multiple resistance and pH regulation protein F	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
LZS3_k127_3420416_21	765914.ThisiDRAFT_0602	3.106e-47	174.0	COG1863@1|root,COG1863@2|Bacteria,1RHD2@1224|Proteobacteria,1S690@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Na+/H+ ion antiporter subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
LZS3_k127_3420416_6	1232410.KI421420_gene3165	2.732e-195	621.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,42PD3@68525|delta/epsilon subdivisions,2WJ58@28221|Deltaproteobacteria,43SD6@69541|Desulfuromonadales	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	mrpD	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
LZS3_k127_3420416_23	756272.Plabr_3037	1.508e-40	153.0	COG1006@1|root,COG1006@2|Bacteria,2J0V2@203682|Planctomycetes	203682|Planctomycetes	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
LZS3_k127_3420416_24	396588.Tgr7_2528	1.149e-39	151.0	COG2111@1|root,COG2111@2|Bacteria,1REGG@1224|Proteobacteria,1S6WN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Na H antiporter, MnhB	mnhB	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
LZS3_k127_3420416_3	383372.Rcas_1768	6.364e-232	741.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2G67I@200795|Chloroflexi,3770I@32061|Chloroflexia	32061|Chloroflexia	C	NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,Proton_antipo_M,Proton_antipo_N
LZS3_k127_3420416_8	338966.Ppro_1684	5.377e-150	491.0	COG0668@1|root,COG0668@2|Bacteria,1MXH4@1224|Proteobacteria	1224|Proteobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
LZS3_k127_3420416_7	290512.Paes_0606	1.444e-161	520.0	COG0189@1|root,COG0189@2|Bacteria,1FEIE@1090|Chlorobi	1090|Chlorobi	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
LZS3_k127_3420416_5	237368.SCABRO_01667	3.002e-203	651.0	COG3930@1|root,COG3930@2|Bacteria,2J4QT@203682|Planctomycetes	203682|Planctomycetes	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
LZS3_k127_3420416_13	1173026.Glo7428_4776	4.491e-107	353.0	COG3741@1|root,COG3741@2|Bacteria	2|Bacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
LZS3_k127_3422284_4	247490.KSU1_B0100	9.756e-170	541.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
LZS3_k127_3422284_39	1122211.JMLW01000057_gene2449	1.78e-08	68.0	COG1403@1|root,COG1403@2|Bacteria,1RATU@1224|Proteobacteria,1S87T@1236|Gammaproteobacteria,1XPK0@135619|Oceanospirillales	135619|Oceanospirillales	L	HNH nucleases	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
LZS3_k127_3422284_33	32049.SYNPCC7002_A1754	3.164e-27	129.0	COG3440@1|root,COG3440@2|Bacteria,1GPU1@1117|Cyanobacteria,1H3VK@1129|Synechococcus	1117|Cyanobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2
LZS3_k127_3422284_41	330214.NIDE2279	1.239e-07	57.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
LZS3_k127_3422284_27	886293.Sinac_1359	1.555e-59	216.0	COG1028@1|root,COG1028@2|Bacteria,2IYKS@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_3422284_2	234267.Acid_1653	2.826e-205	646.0	COG0372@1|root,COG0372@2|Bacteria,3Y32J@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS3_k127_3422284_20	1121859.KB890738_gene2915	8.892e-95	325.0	COG1621@1|root,COG1621@2|Bacteria,4NJ8X@976|Bacteroidetes,47N6D@768503|Cytophagia	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3422284_1	1340493.JNIF01000003_gene1982	2.215e-262	833.0	COG3127@1|root,COG3127@2|Bacteria,3Y2PA@57723|Acidobacteria	57723|Acidobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_3422284_18	63737.Npun_R0239	2.853e-116	384.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
LZS3_k127_3422284_23	1340493.JNIF01000004_gene222	2.698e-80	280.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	2|Bacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_3422284_46	1117318.PRUB_14046	0.0002849	54.0	COG2374@1|root,COG2374@2|Bacteria,1R5QF@1224|Proteobacteria,1SHRH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3422284_30	1340493.JNIF01000003_gene4476	2.004e-50	205.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K07004,ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	ASH,CHU_C,DUF11,SGL
LZS3_k127_3422284_28	926560.KE387023_gene1920	1.522e-57	227.0	COG2374@1|root,COG2374@2|Bacteria,1WM95@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	PFAM Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
LZS3_k127_3422284_36	1122147.AUEH01000057_gene2550	2.833e-21	101.0	COG1340@1|root,COG1340@2|Bacteria,1UI94@1239|Firmicutes,4HFS7@91061|Bacilli,3FBT5@33958|Lactobacillaceae	91061|Bacilli	J	Ion channel	-	-	2.1.1.172	ko:K00564,ko:K10716	-	-	R07234	RC00003	ko00000,ko01000,ko02000,ko03009	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
LZS3_k127_3422284_0	1232410.KI421421_gene3825	0.0	1110.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43U53@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_3422284_29	1232410.KI421421_gene3826	2.499e-57	213.0	COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42T1D@68525|delta/epsilon subdivisions,2X5J9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS3_k127_3422284_14	234267.Acid_1122	7.062e-137	450.0	COG1506@1|root,COG1506@2|Bacteria,3Y3MA@57723|Acidobacteria	57723|Acidobacteria	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
LZS3_k127_3422284_38	765420.OSCT_1590	2.448e-13	82.0	COG0840@1|root,COG1366@1|root,COG0840@2|Bacteria,COG1366@2|Bacteria,2GBRS@200795|Chloroflexi,375NB@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	HAMP,STAS
LZS3_k127_3422284_9	234267.Acid_0798	1.357e-147	488.0	COG4805@1|root,COG4805@2|Bacteria,3Y468@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
LZS3_k127_3422284_15	234267.Acid_7307	1.003e-125	418.0	COG0206@1|root,COG0206@2|Bacteria,3Y2WG@57723|Acidobacteria	57723|Acidobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS3_k127_3422284_24	1267535.KB906767_gene2558	4.766e-78	277.0	COG0849@1|root,COG0849@2|Bacteria,3Y432@57723|Acidobacteria,2JI1Q@204432|Acidobacteriia	204432|Acidobacteriia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
LZS3_k127_3422284_32	234267.Acid_7309	2.914e-36	148.0	COG1589@1|root,COG1589@2|Bacteria,3Y3BQ@57723|Acidobacteria	57723|Acidobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
LZS3_k127_3422284_6	682795.AciX8_3875	1.809e-160	519.0	COG0773@1|root,COG0773@2|Bacteria,3Y304@57723|Acidobacteria,2JIHZ@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS3_k127_3422284_19	234267.Acid_7311	5.523e-100	338.0	COG0707@1|root,COG0707@2|Bacteria,3Y48B@57723|Acidobacteria	57723|Acidobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
LZS3_k127_3422284_22	204669.Acid345_3630	9.653e-83	287.0	COG0772@1|root,COG0772@2|Bacteria,3Y330@57723|Acidobacteria,2JHW0@204432|Acidobacteriia	204432|Acidobacteriia	D	Belongs to the SEDS family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
LZS3_k127_3422284_12	234267.Acid_7313	1.532e-143	470.0	COG0771@1|root,COG0771@2|Bacteria,3Y2JK@57723|Acidobacteria	57723|Acidobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS3_k127_3422284_7	1340493.JNIF01000003_gene3728	3.926e-159	512.0	COG0472@1|root,COG0472@2|Bacteria,3Y2ZH@57723|Acidobacteria	57723|Acidobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
LZS3_k127_3422284_17	1267535.KB906767_gene2565	1.82e-122	409.0	COG0770@1|root,COG0770@2|Bacteria,3Y3I2@57723|Acidobacteria,2JHW4@204432|Acidobacteriia	204432|Acidobacteriia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS3_k127_3422284_5	234267.Acid_7316	6.302e-169	548.0	COG0769@1|root,COG0769@2|Bacteria,3Y38W@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS3_k127_3422284_8	204669.Acid345_3635	7.046e-148	494.0	COG0768@1|root,COG0768@2|Bacteria,3Y2XX@57723|Acidobacteria,2JHPS@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
LZS3_k127_3422284_40	234267.Acid_7318	5.773e-08	62.0	COG2919@1|root,COG2919@2|Bacteria,3Y4JZ@57723|Acidobacteria	57723|Acidobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	DivIC,FtsL
LZS3_k127_3422284_21	1267535.KB906767_gene2569	8.052e-85	289.0	COG0275@1|root,COG0275@2|Bacteria,3Y31S@57723|Acidobacteria,2JHM1@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
LZS3_k127_3422284_34	1382359.JIAL01000001_gene1949	2.036e-26	113.0	COG2001@1|root,COG2001@2|Bacteria,3Y4NF@57723|Acidobacteria,2JJA0@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
LZS3_k127_3422284_3	886293.Sinac_7086	6.497e-182	605.0	COG0330@1|root,COG2217@1|root,COG0330@2|Bacteria,COG2217@2|Bacteria,2IWRY@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	Band_7,E1-E2_ATPase,Hydrolase
LZS3_k127_3422284_25	1487923.DP73_10970	7.411e-71	252.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
LZS3_k127_3422284_26	1123368.AUIS01000001_gene2076	3.04e-64	233.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,2NC5W@225057|Acidithiobacillales	225057|Acidithiobacillales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
LZS3_k127_3422284_43	1261545.MBE-HAL_1529	7.547e-07	59.0	COG0461@1|root,arCOG00029@2157|Archaea,2XVNG@28890|Euryarchaeota,23VBE@183963|Halobacteria	183963|Halobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS3_k127_3422284_10	1267535.KB906767_gene5212	2.327e-145	479.0	COG0318@1|root,COG0318@2|Bacteria,3Y68M@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_3422284_31	1340493.JNIF01000003_gene1477	4.817e-38	159.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,NACHT
LZS3_k127_3422284_11	234267.Acid_0594	2.702e-144	464.0	COG0823@1|root,COG0823@2|Bacteria,3Y36H@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS3_k127_3422284_13	1242864.D187_001763	2.107e-140	490.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2YU45@29|Myxococcales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
LZS3_k127_3422284_44	589865.DaAHT2_1072	1.046e-06	53.0	COG4980@1|root,COG4980@2|Bacteria,1NB49@1224|Proteobacteria,42W0M@68525|delta/epsilon subdivisions,2WRVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS3_k127_3422284_16	344747.PM8797T_20758	1.672e-123	412.0	COG2610@1|root,COG2610@2|Bacteria,2J1TI@203682|Planctomycetes	203682|Planctomycetes	EG	COG2610 H gluconate symporter and related permeases	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
LZS3_k127_3422284_37	1297570.MESS4_260032	1.982e-16	81.0	COG2944@1|root,COG2944@2|Bacteria,1N97N@1224|Proteobacteria,2UJ0U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3422284_35	1267535.KB906767_gene1683	6.197e-24	108.0	COG2942@1|root,COG2942@2|Bacteria	2|Bacteria	G	2-epimerase	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim,Prenyltrans
LZS3_k127_3422539_14	883080.HMPREF9697_02104	9.311e-29	117.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2TWPT@28211|Alphaproteobacteria,3JXB2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_3422539_9	1267535.KB906767_gene809	7.545e-58	213.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,PKD_3
LZS3_k127_3422539_15	1379698.RBG1_1C00001G0517	2.635e-21	109.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
LZS3_k127_3422539_5	671143.DAMO_2385	5.637e-120	396.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
LZS3_k127_3422539_11	234267.Acid_7705	4.359e-51	185.0	COG1959@1|root,COG1959@2|Bacteria,3Y7VG@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS3_k127_3422539_12	671143.DAMO_2378	2.946e-33	131.0	COG2151@1|root,COG2151@2|Bacteria,2NPUI@2323|unclassified Bacteria	2|Bacteria	S	Pfam:DUF59	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
LZS3_k127_3422539_10	671143.DAMO_2379	2.56e-54	199.0	COG0822@1|root,COG0822@2|Bacteria,2NPXN@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
LZS3_k127_3422539_3	671143.DAMO_2380	6.702e-181	575.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
LZS3_k127_3422539_4	1382359.JIAL01000001_gene680	4.568e-121	403.0	COG0719@1|root,COG0719@2|Bacteria,3Y4EK@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
LZS3_k127_3422539_7	472759.Nhal_0689	1.212e-115	377.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,1WWC1@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
LZS3_k127_3422539_1	1267535.KB906767_gene4695	3.387e-278	859.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
LZS3_k127_3422539_16	1267534.KB906757_gene928	2.944e-16	86.0	2C9TJ@1|root,2ZFZD@2|Bacteria,3Y970@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3422539_8	1198114.AciX9_2892	1.024e-104	370.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
LZS3_k127_3422539_0	1123508.JH636443_gene4822	0.0	1148.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
LZS3_k127_3422539_2	1123242.JH636436_gene263	2.81e-238	744.0	COG3119@1|root,COG3119@2|Bacteria,2IX1H@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_3422539_13	1380394.JADL01000020_gene1841	3.328e-32	142.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.38	ko:K00666,ko:K21909	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,AP_endonuc_2,BNR_4
LZS3_k127_3422539_6	1274374.CBLK010000070_gene1292	1.607e-116	391.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
LZS3_k127_3427920_23	1128421.JAGA01000003_gene3456	9.721e-12	65.0	COG2873@1|root,COG2873@2|Bacteria,2NQN4@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
LZS3_k127_3427920_9	880070.Cycma_4907	2.602e-85	301.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,47K2H@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_3427920_11	234267.Acid_5395	6.313e-58	208.0	COG1434@1|root,COG1434@2|Bacteria,3Y4FT@57723|Acidobacteria	57723|Acidobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
LZS3_k127_3427920_17	1382359.JIAL01000001_gene2757	5.164e-44	168.0	COG0009@1|root,COG0009@2|Bacteria,3Y43Z@57723|Acidobacteria,2JI37@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
LZS3_k127_3427920_10	234267.Acid_5394	7.344e-68	247.0	COG0566@1|root,COG0566@2|Bacteria,3Y4GM@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
LZS3_k127_3427920_3	234267.Acid_5393	4.774e-183	582.0	COG2256@1|root,COG2256@2|Bacteria,3Y3F7@57723|Acidobacteria	57723|Acidobacteria	L	AAA ATPase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
LZS3_k127_3427920_12	234267.Acid_7285	9.017e-58	222.0	COG4585@1|root,COG4585@2|Bacteria,3Y8CF@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
LZS3_k127_3427920_22	234267.Acid_2904	4.409e-34	153.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
LZS3_k127_3427920_4	1173024.KI912149_gene6404	7.837e-125	435.0	COG1404@1|root,COG1404@2|Bacteria,1G2F0@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
LZS3_k127_3427920_18	518766.Rmar_0180	1.967e-42	158.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,1FJEP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS3_k127_3427920_21	243231.GSU3442	1.005e-40	154.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,42U37@68525|delta/epsilon subdivisions,2WQ9M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
LZS3_k127_3427920_13	1380394.JADL01000020_gene1841	6.107e-55	199.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.38	ko:K00666,ko:K21909	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,AP_endonuc_2,BNR_4
LZS3_k127_3427920_2	234267.Acid_1107	5.041e-191	613.0	COG0591@1|root,COG0591@2|Bacteria,3Y6FC@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS3_k127_3427920_24	435591.BDI_2307	5.65e-06	57.0	COG1082@1|root,COG1082@2|Bacteria,4NHGW@976|Bacteroidetes,2FNTZ@200643|Bacteroidia,22ZMA@171551|Porphyromonadaceae	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
LZS3_k127_3427920_0	1267535.KB906767_gene3310	5.093e-207	667.0	COG2234@1|root,COG2234@2|Bacteria,3Y6K6@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS3_k127_3427920_1	1267535.KB906767_gene2310	4.015e-195	616.0	COG4948@1|root,COG4948@2|Bacteria,3Y4P2@57723|Acidobacteria,2JP41@204432|Acidobacteriia	204432|Acidobacteriia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_3427920_7	179408.Osc7112_6245	2.965e-90	314.0	COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HH3F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
LZS3_k127_3427920_15	1122164.JHWF01000019_gene482	1.042e-46	174.0	COG3437@1|root,COG3437@2|Bacteria,1QXI4@1224|Proteobacteria	1224|Proteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_3427920_5	272123.Anacy_4124	1.303e-94	323.0	COG4251@1|root,COG4251@2|Bacteria,1GHC4@1117|Cyanobacteria,1HK8D@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY
LZS3_k127_3427920_19	1469607.KK073768_gene1965	1.42e-41	168.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1HJAX@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS3_k127_3427920_16	1242864.D187_001838	6.733e-45	167.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42T9C@68525|delta/epsilon subdivisions,2WP3Z@28221|Deltaproteobacteria,2Z0F7@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_3427920_6	251229.Chro_1594	4.127e-93	324.0	COG2199@1|root,COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,3VKZX@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PAS_3,PAS_9,PHY,Response_reg
LZS3_k127_3427920_14	1173027.Mic7113_0261	8.74e-51	185.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria,1HBA2@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_3427920_8	1173026.Glo7428_2700	3.021e-87	314.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg
LZS3_k127_3427920_20	1297742.A176_04659	5.088e-41	156.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42VIG@68525|delta/epsilon subdivisions,2WS98@28221|Deltaproteobacteria,2YV93@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_3443594_3	234267.Acid_0024	3.305e-162	544.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y3FE@57723|Acidobacteria	2|Bacteria	KU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
LZS3_k127_3443594_16	1038866.KB902791_gene3250	8.559e-38	148.0	COG1846@1|root,COG1846@2|Bacteria,1N6YD@1224|Proteobacteria,2U0SG@28211|Alphaproteobacteria,3JSZ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	MA20_36885	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
LZS3_k127_3443594_15	1267533.KB906733_gene3467	8.731e-41	160.0	COG0204@1|root,COG0204@2|Bacteria,3Y49D@57723|Acidobacteria,2JJ6K@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_3443594_4	234267.Acid_7160	1.705e-146	478.0	COG0154@1|root,COG0154@2|Bacteria,3Y6WA@57723|Acidobacteria	57723|Acidobacteria	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
LZS3_k127_3443594_18	234267.Acid_2465	1.205e-06	60.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3443594_2	357808.RoseRS_4510	1.077e-195	620.0	COG0370@1|root,COG0370@2|Bacteria,2GBTA@200795|Chloroflexi,37667@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
LZS3_k127_3443594_7	357808.RoseRS_4511	5.233e-110	364.0	COG0370@1|root,COG0370@2|Bacteria,2GAJB@200795|Chloroflexi,376HM@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_N
LZS3_k127_3443594_8	357808.RoseRS_4512	2.941e-103	347.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
LZS3_k127_3443594_12	1267534.KB906760_gene1605	4.034e-64	227.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,3Y7PK@57723|Acidobacteria,2JMSU@204432|Acidobacteriia	204432|Acidobacteriia	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
LZS3_k127_3443594_6	234267.Acid_5638	8.969e-120	391.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	CcmA5	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_3443594_5	1267534.KB906755_gene4364	1.367e-142	487.0	COG1680@1|root,COG1680@2|Bacteria,3Y72Z@57723|Acidobacteria	57723|Acidobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3443594_14	91464.S7335_427	4.778e-48	198.0	COG0596@1|root,COG0596@2|Bacteria,1GQGS@1117|Cyanobacteria,1H229@1129|Synechococcus	1117|Cyanobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
LZS3_k127_3443594_1	1267535.KB906767_gene4718	0.0	1045.0	COG0525@1|root,COG0525@2|Bacteria,3Y2JY@57723|Acidobacteria,2JIBS@204432|Acidobacteriia	204432|Acidobacteriia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
LZS3_k127_3443594_10	1340493.JNIF01000004_gene948	1.086e-98	329.0	COG0157@1|root,COG0157@2|Bacteria,3Y2H5@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
LZS3_k127_3443594_13	1382359.JIAL01000001_gene2572	5.628e-55	204.0	COG0340@1|root,COG0340@2|Bacteria,3Y4PB@57723|Acidobacteria,2JJAU@204432|Acidobacteriia	204432|Acidobacteriia	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
LZS3_k127_3443594_9	234267.Acid_7558	4.115e-99	329.0	COG1521@1|root,COG1521@2|Bacteria,3Y398@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
LZS3_k127_3443594_0	1267535.KB906767_gene3483	0.0	1218.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_3443594_11	234267.Acid_1600	1.918e-72	266.0	COG1450@1|root,COG1450@2|Bacteria,3Y6Z6@57723|Acidobacteria	57723|Acidobacteria	NU	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
LZS3_k127_3467527_8	1549858.MC45_15140	5.579e-05	56.0	COG1807@1|root,COG1807@2|Bacteria,1QYQP@1224|Proteobacteria,2TXW3@28211|Alphaproteobacteria,2KETQ@204457|Sphingomonadales	204457|Sphingomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3467527_2	641524.ADICYQ_1665	2.101e-136	451.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes	976|Bacteroidetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_3467527_1	344747.PM8797T_00362	1.045e-139	467.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	-	-	-	-	-	-	-	-	-	-	PHP
LZS3_k127_3467527_9	314278.NB231_16448	5.85e-05	47.0	2DSUP@1|root,33HGU@2|Bacteria	2|Bacteria	-	-	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3467527_0	886293.Sinac_6095	1.488e-240	770.0	COG1073@1|root,COG1073@2|Bacteria,2IYEI@203682|Planctomycetes	203682|Planctomycetes	Q	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
LZS3_k127_3467527_3	1121382.JQKG01000018_gene1099	3.3e-54	196.0	COG2318@1|root,COG2318@2|Bacteria,1WKI3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
LZS3_k127_3467527_4	335543.Sfum_1483	6.443e-43	171.0	COG0484@1|root,COG0484@2|Bacteria,1RHHJ@1224|Proteobacteria,42SMN@68525|delta/epsilon subdivisions,2WPJN@28221|Deltaproteobacteria,2MRYE@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
LZS3_k127_3467527_6	1267535.KB906767_gene2482	5.085e-36	143.0	COG2154@1|root,COG2154@2|Bacteria,3Y8RH@57723|Acidobacteria	57723|Acidobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
LZS3_k127_3467527_7	331869.BAL199_13955	6.98e-06	50.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,4BSI7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2183 Transcriptional accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_3467527_5	102129.Lepto7375DRAFT_2535	3.478e-40	155.0	2DDZV@1|root,32U2A@2|Bacteria,1G7V6@1117|Cyanobacteria,1HCAN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3482289_2	1227266.HMPREF1551_01606	1.256e-22	99.0	COG4282@1|root,COG4282@2|Bacteria,4P56F@976|Bacteroidetes,1IEIX@117743|Flavobacteriia,1EQB5@1016|Capnocytophaga	976|Bacteroidetes	G	hmm pf09346	-	-	-	-	-	-	-	-	-	-	-	-	SMI1_KNR4
LZS3_k127_3482289_0	1385935.N836_20445	1.197e-73	284.0	COG2351@1|root,COG2931@1|root,COG3409@1|root,COG5306@1|root,COG5434@1|root,COG2351@2|Bacteria,COG2931@2|Bacteria,COG3409@2|Bacteria,COG5306@2|Bacteria,COG5434@2|Bacteria,1G4CU@1117|Cyanobacteria,1H7ZW@1150|Oscillatoriales	1117|Cyanobacteria	M	Salmonella virulence plasmid 28.1kDa A protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VRP1
LZS3_k127_3482289_3	81824.XP_001742590.1	3.917e-20	108.0	COG2133@1|root,2QQKP@2759|Eukaryota,38FIA@33154|Opisthokonta	33154|Opisthokonta	G	scavenger receptor activity	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH,PKD
LZS3_k127_3482289_5	1298860.AUEM01000007_gene1815	0.000301	55.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
LZS3_k127_3482289_4	1192034.CAP_0825	3.688e-14	88.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3482289_1	330214.NIDE4326	2.694e-36	145.0	2CK1C@1|root,32SJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3489245_3	1267535.KB906767_gene4753	2.525e-17	95.0	COG0419@1|root,COG0515@1|root,COG0419@2|Bacteria,COG0515@2|Bacteria	2|Bacteria	KLT	protein kinase activity	-	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	AAA_15,AAA_21,DUF4339,TMP_2,Tubulin_2
LZS3_k127_3489245_2	1267535.KB906767_gene3957	5.992e-71	243.0	COG0242@1|root,COG0242@2|Bacteria,3Y4HY@57723|Acidobacteria	57723|Acidobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
LZS3_k127_3489245_1	234267.Acid_2747	2.699e-107	356.0	COG0223@1|root,COG0223@2|Bacteria,3Y32C@57723|Acidobacteria	57723|Acidobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
LZS3_k127_3489245_0	234267.Acid_2748	4.012e-124	409.0	COG1364@1|root,COG1364@2|Bacteria,3Y2PH@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
LZS3_k127_3495949_0	1128421.JAGA01000003_gene3456	4.682e-225	704.0	COG2873@1|root,COG2873@2|Bacteria,2NQN4@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	cysD	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
LZS3_k127_3495949_2	1128421.JAGA01000003_gene3455	1.789e-66	244.0	COG1832@1|root,COG1832@2|Bacteria,2NRIH@2323|unclassified Bacteria	2|Bacteria	S	CoA binding domain	yccU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
LZS3_k127_3495949_3	604331.AUHY01000030_gene978	1.056e-32	132.0	COG0797@1|root,COG0797@2|Bacteria,1WJRE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,LysM
LZS3_k127_3495949_1	1303518.CCALI_02179	5.609e-98	328.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
LZS3_k127_3495949_4	1340493.JNIF01000003_gene4260	7.292e-17	83.0	COG4233@1|root,COG4233@2|Bacteria	2|Bacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084,ko:K06888	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
LZS3_k127_350311_17	596151.DesfrDRAFT_2898	4.104e-09	68.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS3_k127_350311_5	234267.Acid_4566	1.465e-147	489.0	COG0457@1|root,COG0457@2|Bacteria,3Y6HC@57723|Acidobacteria	57723|Acidobacteria	C	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1,TPR_16,TPR_4
LZS3_k127_350311_0	13035.Dacsa_0755	0.0	1320.0	COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria	1117|Cyanobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
LZS3_k127_350311_15	266117.Rxyl_2792	2.607e-42	162.0	COG0819@1|root,COG0819@2|Bacteria,2IGXQ@201174|Actinobacteria	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)	-	-	-	ko:K20896	ko00730,ko01100,map00730,map01100	-	R09993,R11313	RC00197,RC02832	ko00000,ko00001,ko01000	-	-	-	TENA_THI-4
LZS3_k127_350311_12	710685.MycrhN_1732	1.714e-60	221.0	COG0819@1|root,COG0819@2|Bacteria,2IA0S@201174|Actinobacteria,235FM@1762|Mycobacteriaceae	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
LZS3_k127_350311_8	234267.Acid_1226	2.381e-85	289.0	COG0351@1|root,COG0351@2|Bacteria,3Y4DB@57723|Acidobacteria	57723|Acidobacteria	H	TIGRFAM Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
LZS3_k127_350311_16	266748.HY04_14705	1.31e-10	75.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HWM8@117743|Flavobacteriia,3ZRAU@59732|Chryseobacterium	976|Bacteroidetes	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
LZS3_k127_350311_13	575540.Isop_2795	3.191e-51	205.0	COG1409@1|root,COG1409@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
LZS3_k127_350311_6	1267535.KB906767_gene310	3.352e-101	344.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_350311_10	32057.KB217478_gene1096	1.278e-68	237.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria,1HMWG@1161|Nostocales	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS3_k127_350311_2	641524.ADICYQ_3703	5.435e-212	674.0	COG2936@1|root,COG2936@2|Bacteria,4NHJU@976|Bacteroidetes,47XH7@768503|Cytophagia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
LZS3_k127_350311_1	234267.Acid_6976	7.121e-217	694.0	28JZQ@1|root,2Z9PN@2|Bacteria,3Y4UW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_350311_4	234267.Acid_3103	5.706e-171	546.0	COG4948@1|root,COG4948@2|Bacteria,3Y46A@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
LZS3_k127_350311_14	28583.AMAG_11518T0	4.643e-46	177.0	COG2301@1|root,2QQPK@2759|Eukaryota,38GJH@33154|Opisthokonta,3NXCF@4751|Fungi	4751|Fungi	F	Citrate lyase	-	-	-	ko:K11390	-	-	-	-	ko00000,ko01000	-	-	-	HpcH_HpaI
LZS3_k127_350311_11	1382306.JNIM01000001_gene713	3.815e-61	214.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
LZS3_k127_350311_9	1231057.AMGD01000004_gene2899	5.751e-71	249.0	COG0363@1|root,COG0363@2|Bacteria,1TQK7@1239|Firmicutes	1239|Firmicutes	G	Psort location Cytoplasmic, score 8.87	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	-
LZS3_k127_350311_3	756272.Plabr_1060	6.339e-173	552.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
LZS3_k127_350311_7	497964.CfE428DRAFT_2558	3.582e-95	324.0	COG0673@1|root,COG0673@2|Bacteria,46TTF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_3513146_10	1266925.JHVX01000014_gene1591	2.52e-25	116.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2WHQF@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
LZS3_k127_3513146_4	344747.PM8797T_16228	4.612e-68	246.0	COG1680@1|root,COG1680@2|Bacteria,2IZJ5@203682|Planctomycetes	203682|Planctomycetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_3513146_6	113395.AXAI01000018_gene4844	3.09e-38	150.0	COG0662@1|root,COG0662@2|Bacteria,1N56T@1224|Proteobacteria,2UCUS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_3513146_3	1382356.JQMP01000001_gene698	1.347e-96	332.0	COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi,27XRM@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS3_k127_3513146_1	234267.Acid_2632	4.177e-126	417.0	COG0737@1|root,COG0737@2|Bacteria,3Y82P@57723|Acidobacteria	57723|Acidobacteria	F	5'-nucleotidase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos
LZS3_k127_3513146_7	234267.Acid_6303	5.614e-29	128.0	COG1426@1|root,COG1426@2|Bacteria,3Y5KP@57723|Acidobacteria	57723|Acidobacteria	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
LZS3_k127_3513146_5	1340493.JNIF01000003_gene2805	8.817e-53	191.0	COG1607@1|root,COG1607@2|Bacteria,3Y53T@57723|Acidobacteria	57723|Acidobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS3_k127_3513146_11	234267.Acid_0134	1.704e-20	96.0	295WJ@1|root,2ZT7G@2|Bacteria,3Y8RM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3513146_8	234267.Acid_0135	5.773e-28	120.0	COG0457@1|root,COG0457@2|Bacteria,3Y99M@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3513146_0	1173028.ANKO01000250_gene2314	2.896e-278	868.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
LZS3_k127_3513146_2	1340493.JNIF01000004_gene359	3.511e-125	415.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_03425	-	3.1.6.14	ko:K01137,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
LZS3_k127_3513146_9	1340493.JNIF01000004_gene703	2.388e-27	112.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_352232_1	1232410.KI421421_gene3883	1.177e-57	212.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria,43UI6@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
LZS3_k127_352232_3	85643.Tmz1t_2649	7.099e-33	132.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KWBT@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_352232_2	1191523.MROS_1860	5.752e-42	170.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
LZS3_k127_352232_0	234267.Acid_2270	3.875e-87	308.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3541779_20	1267535.KB906767_gene1049	2.276e-23	100.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
LZS3_k127_3541779_18	1267535.KB906767_gene2728	8.283e-35	135.0	COG0234@1|root,COG0234@2|Bacteria,3Y4VQ@57723|Acidobacteria	57723|Acidobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS3_k127_3541779_2	1267535.KB906767_gene2727	1.526e-255	796.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria,2JIV1@204432|Acidobacteriia	204432|Acidobacteriia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS3_k127_3541779_9	234267.Acid_4451	3.336e-110	370.0	COG0673@1|root,COG0673@2|Bacteria,3Y71T@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_3541779_5	234267.Acid_6148	7.99e-134	444.0	COG1921@1|root,COG1921@2|Bacteria,3Y6KN@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3541779_7	234267.Acid_6148	2.385e-118	400.0	COG1921@1|root,COG1921@2|Bacteria,3Y6KN@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3541779_13	1340493.JNIF01000003_gene1795	1.194e-75	259.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria	57723|Acidobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
LZS3_k127_3541779_21	204669.Acid345_4505	1.124e-22	105.0	COG0236@1|root,COG0236@2|Bacteria,3Y54V@57723|Acidobacteria,2JJPU@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS3_k127_3541779_3	234267.Acid_1167	4.87e-201	633.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_3541779_11	234267.Acid_1166	1.236e-93	314.0	COG2086@1|root,COG2086@2|Bacteria,3Y2PD@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
LZS3_k127_3541779_6	234267.Acid_1165	8.932e-125	407.0	COG2025@1|root,COG2025@2|Bacteria,3Y4SJ@57723|Acidobacteria	57723|Acidobacteria	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
LZS3_k127_3541779_14	192952.MM_0501	3.917e-68	234.0	COG3865@1|root,arCOG09469@2157|Archaea,2Y3A8@28890|Euryarchaeota,2NB0H@224756|Methanomicrobia	224756|Methanomicrobia	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
LZS3_k127_3541779_0	1267535.KB906767_gene223	6.023e-313	996.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_3541779_16	1249627.D779_1825	1.993e-48	189.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1SYV1@1236|Gammaproteobacteria,1X2IS@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
LZS3_k127_3541779_1	1047013.AQSP01000118_gene1236	4.004e-288	917.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_3541779_10	234267.Acid_0702	1.23e-105	359.0	COG0673@1|root,COG0673@2|Bacteria,3Y2KV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_3541779_17	1122603.ATVI01000005_gene3042	1.029e-41	164.0	COG0668@1|root,COG0668@2|Bacteria,1N4UN@1224|Proteobacteria,1T9TX@1236|Gammaproteobacteria,1XBUR@135614|Xanthomonadales	135614|Xanthomonadales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
LZS3_k127_3541779_22	251221.35212492	1.844e-20	101.0	COG2239@1|root,COG2239@2|Bacteria,1G0CN@1117|Cyanobacteria	1117|Cyanobacteria	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS3_k127_3541779_8	1122603.ATVI01000005_gene3040	4.728e-116	387.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1X4NW@135614|Xanthomonadales	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS3_k127_3541779_4	1340493.JNIF01000004_gene204	2.782e-147	478.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	-	-	-	-	-	-	-	-	-	-	Enolase_C,Enolase_N
LZS3_k127_3541779_12	234267.Acid_1440	2.423e-76	266.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2,RNA_lig_T4_1
LZS3_k127_3541779_15	234267.Acid_4014	1.463e-64	235.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_3541779_23	1111728.ATYS01000003_gene1872	1.456e-07	57.0	2DRAG@1|root,33AYH@2|Bacteria,1P6TA@1224|Proteobacteria,1SUCI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3582259_4	1037409.BJ6T_24690	1.983e-42	159.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2TWPT@28211|Alphaproteobacteria,3JVV3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
LZS3_k127_3582259_1	760117.JN27_17825	1.941e-158	511.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2VI1T@28216|Betaproteobacteria,47403@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Mo-co oxidoreductase dimerisation domain	-	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
LZS3_k127_3582259_3	1219084.AP014508_gene136	2.376e-72	257.0	COG3181@1|root,COG3181@2|Bacteria	2|Bacteria	E	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
LZS3_k127_3582259_2	204669.Acid345_2071	4.705e-144	484.0	COG4206@1|root,COG4206@2|Bacteria,3Y30M@57723|Acidobacteria,2JI7U@204432|Acidobacteriia	204432|Acidobacteriia	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
LZS3_k127_3582259_0	204669.Acid345_2819	1.566e-238	768.0	COG2234@1|root,COG2234@2|Bacteria,3Y435@57723|Acidobacteria,2JKND@204432|Acidobacteriia	204432|Acidobacteriia	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
LZS3_k127_3583294_4	1163409.UUA_03593	1.187e-135	443.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1X3GS@135614|Xanthomonadales	135614|Xanthomonadales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	ko:K14660	-	-	-	-	ko00000,ko01000	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_3583294_9	1267533.KB906736_gene1074	1.294e-16	85.0	COG0236@1|root,COG0236@2|Bacteria,3Y8JV@57723|Acidobacteria,2JNHU@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS3_k127_3583294_8	1267535.KB906767_gene4265	7.279e-25	106.0	2FHRB@1|root,349IU@2|Bacteria,3Y8GP@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3583294_7	497964.CfE428DRAFT_4946	3.432e-48	182.0	2EK8J@1|root,33DYX@2|Bacteria,46VTQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3583294_0	234267.Acid_1174	1.784e-270	854.0	COG0210@1|root,COG0210@2|Bacteria,3Y2W8@57723|Acidobacteria	57723|Acidobacteria	L	PFAM UvrD REP helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS3_k127_3583294_1	234267.Acid_1175	2.092e-234	738.0	COG0531@1|root,COG0531@2|Bacteria,3Y2R3@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS3_k127_3583294_5	234267.Acid_1399	1.647e-93	320.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
LZS3_k127_3583294_2	234267.Acid_7159	2.624e-163	530.0	COG0169@1|root,COG0710@1|root,COG0169@2|Bacteria,COG0710@2|Bacteria,3Y2Y4@57723|Acidobacteria	57723|Acidobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	1.1.1.25,4.2.1.10	ko:K00014,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
LZS3_k127_3583294_3	574087.Acear_1870	1.581e-153	499.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3WBGE@53433|Halanaerobiales	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
LZS3_k127_3583294_6	635013.TherJR_1606	5.038e-66	228.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,261J7@186807|Peptococcaceae	186801|Clostridia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS3_k127_3603822_2	156889.Mmc1_2548	3.629e-78	266.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_3603822_3	1042209.HK44_016080	7.188e-56	203.0	2EE1U@1|root,337WK@2|Bacteria,1NXPV@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3303)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3303
LZS3_k127_3603822_0	234267.Acid_5012	6.289e-280	869.0	COG0008@1|root,COG0008@2|Bacteria,3Y7DS@57723|Acidobacteria	57723|Acidobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	-	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
LZS3_k127_3603822_1	234267.Acid_5011	7.102e-206	649.0	COG0008@1|root,COG0008@2|Bacteria,3Y465@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
LZS3_k127_3648775_4	502025.Hoch_4995	3.443e-142	465.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,2Z2W5@29|Myxococcales	28221|Deltaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS3_k127_3648775_0	649638.Trad_0897	0.0	1219.0	COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	dehydrogenase e1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
LZS3_k127_3648775_7	639030.JHVA01000001_gene2540	6.991e-114	376.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_3648775_8	1403819.BATR01000090_gene2637	4.527e-110	370.0	2DV29@1|root,33TNQ@2|Bacteria	2|Bacteria	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3648775_9	1242864.D187_008439	7.279e-77	265.0	COG5634@1|root,COG5634@2|Bacteria,1Q8ZX@1224|Proteobacteria,42Z0W@68525|delta/epsilon subdivisions,2WU0S@28221|Deltaproteobacteria,2YYU6@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2278)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2278
LZS3_k127_3648775_15	667014.Thein_1735	3.824e-27	129.0	COG3533@1|root,COG3533@2|Bacteria,2GIE0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3648775_1	1267535.KB906767_gene1639	5.807e-204	674.0	COG4775@1|root,COG4775@2|Bacteria,3Y9FK@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_3648775_13	1340493.JNIF01000004_gene926	4.239e-33	149.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM_assoc,PEGA
LZS3_k127_3648775_21	314265.R2601_04438	1.21e-06	62.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
LZS3_k127_3648775_11	195250.CM001776_gene539	2.406e-68	246.0	COG0665@1|root,COG0665@2|Bacteria,1G4DH@1117|Cyanobacteria,1GYZP@1129|Synechococcus	1117|Cyanobacteria	C	Sarcosine oxidase	solA	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2
LZS3_k127_3648775_12	234267.Acid_1760	5.283e-64	224.0	COG0566@1|root,COG0566@2|Bacteria,3Y4WG@57723|Acidobacteria	57723|Acidobacteria	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
LZS3_k127_3648775_19	234267.Acid_4740	1.32e-09	66.0	COG0745@1|root,COG0745@2|Bacteria	234267.Acid_4740|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3648775_14	357808.RoseRS_4464	8.908e-29	119.0	COG1917@1|root,COG1917@2|Bacteria,2G7C7@200795|Chloroflexi,377HW@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3648775_17	1101195.Meth11DRAFT_1951	5.451e-14	74.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,2KN2F@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
LZS3_k127_3648775_16	471854.Dfer_0363	1.964e-17	87.0	COG1917@1|root,COG1917@2|Bacteria,4PC6H@976|Bacteroidetes,47WW5@768503|Cytophagia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3648775_3	1267533.KB906737_gene1877	8.1e-153	499.0	COG0154@1|root,COG0154@2|Bacteria,3Y41H@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
LZS3_k127_3648775_10	518766.Rmar_0958	6.49e-73	251.0	COG3828@1|root,COG3828@2|Bacteria,4PND4@976|Bacteroidetes	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_3648775_2	1267535.KB906767_gene5169	1.344e-192	613.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS3_k127_3648775_6	1340493.JNIF01000003_gene4564	4.061e-115	385.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	ubiG	-	2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181	ko:K00568,ko:K18827	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781,R10657,R10658	RC00002,RC00003,RC00078,RC00392,RC01895,RC03220	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS3_k127_3648775_20	1173029.JH980292_gene2739	1.129e-08	67.0	COG2755@1|root,COG2755@2|Bacteria,1G33R@1117|Cyanobacteria,1H91S@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like lipase acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS3_k127_3661035_5	748247.AZKH_3960	4.116e-60	230.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KVXP@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_7,PAS_9,Response_reg
LZS3_k127_3661035_8	395961.Cyan7425_0749	2.012e-16	87.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS_8,PAS_9,Response_reg,SpoIIE
LZS3_k127_3661035_7	573413.Spirs_1697	4.507e-28	119.0	COG0745@1|root,COG0745@2|Bacteria,2J7CK@203691|Spirochaetes	203691|Spirochaetes	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07657,ko:K07658,ko:K18941	ko02020,map02020	M00434,M00716,M00717	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_3661035_1	234267.Acid_6148	6.05e-114	385.0	COG1921@1|root,COG1921@2|Bacteria,3Y6KN@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3661035_3	234267.Acid_6148	7.176e-107	369.0	COG1921@1|root,COG1921@2|Bacteria,3Y6KN@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3661035_2	1341151.ASZU01000001_gene725	6.384e-109	362.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,27AU9@186824|Thermoactinomycetaceae	91061|Bacilli	S	AAA domain, putative AbiEii toxin, Type IV TA system	drrA1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_3661035_6	635013.TherJR_1109	8.385e-52	196.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,24B28@186801|Clostridia,26718@186807|Peptococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
LZS3_k127_3661035_9	1396141.BATP01000001_gene5356	5.797e-14	78.0	COG2382@1|root,COG2382@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
LZS3_k127_3661035_0	314230.DSM3645_20627	2.039e-130	431.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_3661035_4	234267.Acid_1297	1.344e-98	331.0	COG0324@1|root,COG0324@2|Bacteria,3Y3CE@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
LZS3_k127_3708073_16	639030.JHVA01000001_gene2705	1.953e-20	104.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_3708073_15	1267535.KB906767_gene3824	8.712e-30	131.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_3708073_18	278963.ATWD01000001_gene2540	1.035e-19	100.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_3708073_8	234267.Acid_0971	9.165e-69	239.0	COG1704@1|root,COG1704@2|Bacteria,3Y4QG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
LZS3_k127_3708073_10	234267.Acid_0972	2.595e-49	184.0	COG1708@1|root,COG1708@2|Bacteria,3Y7NX@57723|Acidobacteria	57723|Acidobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3708073_11	204669.Acid345_1517	1.287e-44	172.0	COG1512@1|root,COG1512@2|Bacteria,3Y4JT@57723|Acidobacteria,2JJBI@204432|Acidobacteriia	204432|Acidobacteriia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
LZS3_k127_3708073_7	234267.Acid_1849	4.863e-85	289.0	COG1028@1|root,COG1028@2|Bacteria,3Y6JP@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_3708073_3	1279038.KB907341_gene1895	3.076e-107	357.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,2UAJA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
LZS3_k127_3708073_1	1267535.KB906767_gene473	1.309e-116	387.0	28JXN@1|root,30T38@2|Bacteria,3Y61P@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
LZS3_k127_3708073_2	1340493.JNIF01000003_gene1832	3.046e-112	372.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
LZS3_k127_3708073_17	84531.JMTZ01000168_gene725	2.402e-20	97.0	290G0@1|root,2ZN55@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3708073_20	204669.Acid345_1753	1.356e-08	61.0	2EQAC@1|root,33HWH@2|Bacteria,3Y5W6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3708073_19	1206744.BAGL01000007_gene3901	1.305e-09	70.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,4FX2G@85025|Nocardiaceae	201174|Actinobacteria	S	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
LZS3_k127_3708073_4	1340493.JNIF01000003_gene3944	1.957e-98	344.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
LZS3_k127_3708073_14	1267535.KB906767_gene5098	1.775e-32	132.0	2FGSP@1|root,348N1@2|Bacteria,3Y8G3@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3708073_13	1340493.JNIF01000003_gene3768	3.926e-35	145.0	2CBEY@1|root,33YTG@2|Bacteria,3Y88I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3708073_9	1123237.Salmuc_03926	1.633e-52	198.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria	2|Bacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.1.1.199	ko:K03438,ko:K13292	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	LGT
LZS3_k127_3708073_0	1340493.JNIF01000003_gene3306	1.444e-117	391.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_3708073_5	344747.PM8797T_25646	1.689e-89	302.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
LZS3_k127_3708073_6	1411123.JQNH01000001_gene3166	5.623e-86	303.0	COG4948@1|root,COG4948@2|Bacteria,1MV2S@1224|Proteobacteria,2TTFB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
LZS3_k127_3708073_12	1340493.JNIF01000003_gene3484	2.582e-41	154.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
LZS3_k127_3726785_3	1267535.KB906767_gene1983	8.825e-155	494.0	COG0798@1|root,COG0798@2|Bacteria,3Y69M@57723|Acidobacteria,2JP2H@204432|Acidobacteriia	57723|Acidobacteria	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
LZS3_k127_3726785_4	234267.Acid_6234	1.574e-125	415.0	COG1682@1|root,COG1682@2|Bacteria,3Y8HI@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
LZS3_k127_3726785_0	234267.Acid_6233	1.499e-216	702.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25
LZS3_k127_3726785_5	234267.Acid_6226	8.459e-122	395.0	COG1209@1|root,COG1209@2|Bacteria,3Y2ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS3_k127_3726785_8	1267535.KB906767_gene2836	3.47e-89	317.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS3_k127_3726785_16	1267535.KB906767_gene5109	6.915e-44	162.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
LZS3_k127_3726785_10	234267.Acid_7174	4.097e-72	255.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_3726785_12	1382359.JIAL01000001_gene1618	7.494e-64	228.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_3726785_17	234267.Acid_7290	3.154e-22	98.0	COG5660@1|root,COG5660@2|Bacteria,3Y5KK@57723|Acidobacteria	57723|Acidobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS3_k127_3726785_13	234267.Acid_1315	8.22e-46	174.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	1.8.1.9	ko:K00384,ko:K10914	ko00450,ko02020,ko02024,ko02025,ko02026,ko05111,map00450,map02020,map02024,map02025,map02026,map05111	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_3726785_2	234267.Acid_2209	5.179e-184	583.0	COG4867@1|root,COG4867@2|Bacteria,3Y2VU@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
LZS3_k127_3726785_1	278963.ATWD01000001_gene4056	6.708e-212	668.0	COG1239@1|root,COG1239@2|Bacteria,3Y3FM@57723|Acidobacteria,2JHY2@204432|Acidobacteriia	204432|Acidobacteriia	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Sigma54_activat
LZS3_k127_3726785_9	234267.Acid_1756	2.244e-85	290.0	COG1378@1|root,COG1378@2|Bacteria,3Y66F@57723|Acidobacteria	57723|Acidobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
LZS3_k127_3726785_7	639030.JHVA01000001_gene1899	5.415e-98	330.0	COG0662@1|root,COG1917@1|root,COG0662@2|Bacteria,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	Cupin_2,NeuB
LZS3_k127_3726785_15	234267.Acid_5838	1.323e-45	173.0	COG2606@1|root,COG2606@2|Bacteria,3Y54I@57723|Acidobacteria	57723|Acidobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
LZS3_k127_3726785_6	794903.OPIT5_11955	8.297e-119	397.0	COG2327@1|root,COG2327@2|Bacteria,46YBH@74201|Verrucomicrobia,3K99B@414999|Opitutae	414999|Opitutae	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
LZS3_k127_3726785_11	479434.Sthe_3482	4.539e-69	238.0	COG2041@1|root,COG2041@2|Bacteria,2GB1N@200795|Chloroflexi,27Z7Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
LZS3_k127_3727176_7	1123242.JH636438_gene5875	4.053e-139	458.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_3727176_5	665952.HMPREF1015_00186	3.548e-162	526.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,1ZC6M@1386|Bacillus	91061|Bacilli	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
LZS3_k127_3727176_8	886293.Sinac_1624	1.016e-103	345.0	COG0546@1|root,COG0546@2|Bacteria,2IYT6@203682|Planctomycetes	203682|Planctomycetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS3_k127_3727176_2	344747.PM8797T_30566	1.866e-186	594.0	COG1012@1|root,COG1012@2|Bacteria,2IXUV@203682|Planctomycetes	203682|Planctomycetes	C	COG1012 NAD-dependent aldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS3_k127_3727176_4	926566.Terro_1497	3.342e-163	526.0	COG0004@1|root,COG0004@2|Bacteria,3Y2VR@57723|Acidobacteria,2JHMR@204432|Acidobacteriia	204432|Acidobacteriia	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
LZS3_k127_3727176_9	234267.Acid_7189	5.683e-50	180.0	COG0347@1|root,COG0347@2|Bacteria,3Y4TF@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
LZS3_k127_3727176_1	234267.Acid_7188	9.376e-208	674.0	COG2844@1|root,COG2844@2|Bacteria,3Y2FJ@57723|Acidobacteria	57723|Acidobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
LZS3_k127_3727176_0	1340493.JNIF01000003_gene2321	0.0	1202.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,3Y6I3@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_3727176_6	1267535.KB906767_gene3579	7.433e-145	467.0	COG1312@1|root,COG1312@2|Bacteria,3Y6WX@57723|Acidobacteria	57723|Acidobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
LZS3_k127_3727176_10	118173.KB235914_gene3364	1.39e-16	83.0	COG4974@1|root,COG4974@2|Bacteria,1G224@1117|Cyanobacteria,1H8SW@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS3_k127_3727176_3	344747.PM8797T_03274	7.793e-180	583.0	COG3593@1|root,COG3593@2|Bacteria,2J4IU@203682|Planctomycetes	203682|Planctomycetes	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3727176_11	330214.NIDE2614	1.561e-11	64.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218,ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin,UPF0066,YafQ_toxin
LZS3_k127_3742370_8	497964.CfE428DRAFT_2042	8.671e-72	248.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS3_k127_3742370_2	1267535.KB906767_gene218	5.67e-193	609.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3742370_1	1379270.AUXF01000002_gene1544	4.064e-211	671.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS3_k127_3742370_4	234267.Acid_2025	1.806e-123	409.0	COG0544@1|root,COG0544@2|Bacteria,3Y45D@57723|Acidobacteria	57723|Acidobacteria	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
LZS3_k127_3742370_6	204669.Acid345_1560	2.114e-93	312.0	COG0740@1|root,COG0740@2|Bacteria,3Y2SY@57723|Acidobacteria,2JHPB@204432|Acidobacteriia	204432|Acidobacteriia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS3_k127_3742370_9	653733.Selin_2132	2.515e-52	193.0	2CAZH@1|root,2Z7RU@2|Bacteria	2|Bacteria	-	-	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
LZS3_k127_3742370_0	324602.Caur_1881	0.0	1027.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS3_k127_3742370_5	926550.CLDAP_30830	8.842e-116	377.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
LZS3_k127_3742370_7	518766.Rmar_1923	1.169e-82	287.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1FISB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
LZS3_k127_3742370_10	234267.Acid_5970	3.216e-50	197.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT,PGAP1
LZS3_k127_3742370_3	713586.KB900536_gene2395	5.919e-145	465.0	COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,1S93R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
LZS3_k127_3742370_11	234267.Acid_0297	6.644e-32	135.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT,PGAP1
LZS3_k127_3742370_12	590998.Celf_3522	3.112e-08	66.0	COG3468@1|root,COG4932@1|root,COG3468@2|Bacteria,COG4932@2|Bacteria,2HCJX@201174|Actinobacteria	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	B_lectin,CHAP,TIG
LZS3_k127_3742370_13	391625.PPSIR1_12803	8.377e-07	61.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_3785544_3	1267535.KB906767_gene2388	0.0002943	51.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
LZS3_k127_3785544_1	1267535.KB906767_gene215	1.236e-91	313.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria,2JKP5@204432|Acidobacteriia	204432|Acidobacteriia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
LZS3_k127_3785544_0	1163617.SCD_n00025	4.446e-188	596.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria	1224|Proteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_3800282_0	1227499.C493_09383	1.431e-45	189.0	2DZ85@1|root,2N5HN@2157|Archaea,2Y0TM@28890|Euryarchaeota,23Y9H@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
LZS3_k127_382706_3	1340493.JNIF01000004_gene436	5.162e-23	101.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	psbV	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797	-	ko:K02720	ko00195,ko01100,map00195,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	iJN678.psbV	Cytochrom_C,Cytochrom_C550,Cytochrom_CIII,Cytochrome_C7
LZS3_k127_382706_1	269799.Gmet_1810	9.208e-112	388.0	COG0243@1|root,COG0243@2|Bacteria,1R4RR@1224|Proteobacteria,42PA5@68525|delta/epsilon subdivisions,2WM0K@28221|Deltaproteobacteria,43W1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	qrcB	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_382706_2	443143.GM18_3947	2.919e-95	317.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,43TY6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_382706_0	269799.Gmet_1812	7.813e-142	464.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
LZS3_k127_382706_4	443143.GM18_3949	5.617e-07	58.0	2DSXF@1|root,33HTI@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS3_k127_382706_5	570967.JMLV01000020_gene406	1.692e-06	57.0	COG2010@1|root,COG2010@2|Bacteria,1N7JQ@1224|Proteobacteria,2UMJP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS3_k127_3842848_16	1267535.KB906767_gene1940	5.591e-33	129.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	VY92_08690	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
LZS3_k127_3842848_13	1288963.ADIS_4387	1.385e-59	222.0	COG4948@1|root,COG4948@2|Bacteria,4NEPP@976|Bacteroidetes,47M8J@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_3842848_10	234267.Acid_2964	1.562e-70	250.0	COG2930@1|root,COG2930@2|Bacteria,3Y6Q0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
LZS3_k127_3842848_19	525897.Dbac_2186	1.1e-16	82.0	2DRFV@1|root,33BJD@2|Bacteria,1NM2T@1224|Proteobacteria,42WGX@68525|delta/epsilon subdivisions,2WR8G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3842848_8	1340493.JNIF01000004_gene944	5.399e-96	330.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_3842848_15	1267534.KB906756_gene712	1.836e-35	142.0	2A3BS@1|root,30RTX@2|Bacteria,3Y943@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3842848_2	234267.Acid_4101	2.475e-197	623.0	COG0577@1|root,COG0577@2|Bacteria,3Y6CK@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_3842848_4	234267.Acid_4102	1.522e-139	460.0	COG0845@1|root,COG0845@2|Bacteria,3Y6E7@57723|Acidobacteria	57723|Acidobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3842848_5	234267.Acid_4103	8.865e-133	439.0	COG0845@1|root,COG0845@2|Bacteria,3Y7DU@57723|Acidobacteria	57723|Acidobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
LZS3_k127_3842848_9	1267535.KB906767_gene2305	7.257e-95	323.0	COG0845@1|root,COG0845@2|Bacteria,3Y6UQ@57723|Acidobacteria	57723|Acidobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3842848_7	1340493.JNIF01000003_gene2002	1.288e-116	391.0	28KEJ@1|root,2Z9QB@2|Bacteria,3Y7P1@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3842848_21	595460.RRSWK_06791	1.68e-10	70.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2,Sulfatase
LZS3_k127_3842848_14	234267.Acid_1280	1.249e-43	168.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS3_k127_3842848_0	234267.Acid_1055	2.89e-216	681.0	COG0277@1|root,COG0277@2|Bacteria,3Y68N@57723|Acidobacteria	57723|Acidobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS3_k127_3842848_3	1267535.KB906767_gene4275	7.531e-174	567.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,3Y3VV@57723|Acidobacteria,2JHRV@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
LZS3_k127_3842848_6	1122223.KB890687_gene2492	1.656e-122	419.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_3842848_12	234267.Acid_3219	1.238e-59	231.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3842848_1	234267.Acid_4698	3.02e-210	671.0	COG0405@1|root,COG0405@2|Bacteria,3Y6KV@57723|Acidobacteria	57723|Acidobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_3916239_3	234267.Acid_0907	1.691e-50	183.0	COG0103@1|root,COG0103@2|Bacteria,3Y4IK@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS3_k127_3916239_2	234267.Acid_0908	1.042e-52	189.0	COG0102@1|root,COG0102@2|Bacteria,3Y4U5@57723|Acidobacteria	57723|Acidobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
LZS3_k127_3916239_4	234267.Acid_1042	6.31e-48	172.0	COG1146@1|root,COG1146@2|Bacteria,3Y59N@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4
LZS3_k127_3916239_1	497964.CfE428DRAFT_1973	3.954e-190	607.0	COG1488@1|root,COG1488@2|Bacteria,46SAG@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
LZS3_k127_3916239_0	234267.Acid_3590	1.982e-320	1020.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF11,DUF4384,Flg_new,TonB_dep_Rec
LZS3_k127_3945760_2	234267.Acid_0020	1.061e-121	411.0	COG0457@1|root,COG0457@2|Bacteria,3Y6VN@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3945760_1	234267.Acid_0019	1.265e-183	595.0	2EY4D@1|root,33RD9@2|Bacteria,3Y6DM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3945760_5	234267.Acid_0018	8.121e-33	133.0	COG0789@1|root,COG0789@2|Bacteria,3Y56I@57723|Acidobacteria	57723|Acidobacteria	K	regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
LZS3_k127_3945760_4	1128421.JAGA01000004_gene2613	4.922e-59	213.0	COG0496@1|root,COG0496@2|Bacteria,2NPCG@2323|unclassified Bacteria	2|Bacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	iSFxv_1172.SFxv_3035	SurE
LZS3_k127_3945760_3	1379270.AUXF01000005_gene474	6.232e-113	390.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSZA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
LZS3_k127_3945760_0	1519464.HY22_07105	1.128e-300	945.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
LZS3_k127_3945760_6	391625.PPSIR1_13043	2.312e-19	93.0	COG2606@1|root,COG2606@2|Bacteria,1R9YR@1224|Proteobacteria,42SA8@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	YbaK proline--tRNA ligase associated domain protein	yeaK	GO:0002161,GO:0002196,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006417,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0045727,GO:0045903,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:2000112	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
LZS3_k127_3960924_20	56110.Oscil6304_4373	7.785e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1HAC0@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_11,TPR_2,TPR_8
LZS3_k127_3960924_4	1340493.JNIF01000004_gene935	5.109e-98	326.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_3960924_1	518766.Rmar_1535	2.027e-265	834.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1FIZ6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	heavy metal translocating P-type ATPase	copB	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS3_k127_3960924_3	1267535.KB906767_gene661	3.696e-110	368.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
LZS3_k127_3960924_12	1089550.ATTH01000001_gene224	7.32e-34	138.0	COG0789@1|root,COG0789@2|Bacteria,4NW77@976|Bacteroidetes,1FK6E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	MerR, DNA binding	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR_1
LZS3_k127_3960924_14	426114.THI_3081	2.872e-23	103.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF836
LZS3_k127_3960924_2	880070.Cycma_1902	4.892e-206	664.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3960924_7	1033743.CAES01000046_gene265	8.977e-61	222.0	COG0673@1|root,COG0673@2|Bacteria,1UUTP@1239|Firmicutes,4HYQG@91061|Bacilli	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_3960924_10	639030.JHVA01000001_gene2115	1.085e-46	181.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y8N8@57723|Acidobacteria,2JNIX@204432|Acidobacteriia	204432|Acidobacteriia	EG	L-rhamnose-proton symport protein (RhaT)	-	-	-	-	-	-	-	-	-	-	-	-	RhaT
LZS3_k127_3960924_5	1340493.JNIF01000003_gene4759	1.474e-97	334.0	COG2355@1|root,COG2355@2|Bacteria,3Y3RS@57723|Acidobacteria	57723|Acidobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
LZS3_k127_3960924_9	314230.DSM3645_22434	2.366e-53	200.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS3_k127_3960924_17	324602.Caur_1104	7.605e-20	98.0	COG2942@1|root,COG2942@2|Bacteria,2G8X6@200795|Chloroflexi,375Z3@32061|Chloroflexia	32061|Chloroflexia	G	PFAM N-acylglucosamine 2-epimerase	-	-	5.1.3.11,5.1.3.8	ko:K01787,ko:K16213	ko00520,map00520	-	R01207,R01445,R10810	RC00289,RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
LZS3_k127_3960924_11	762903.Pedsa_0685	1.193e-37	154.0	COG2942@1|root,COG2942@2|Bacteria,4NEFV@976|Bacteroidetes	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
LZS3_k127_3960924_0	1267535.KB906767_gene5123	0.0	1543.0	COG1038@1|root,COG1038@2|Bacteria	2|Bacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
LZS3_k127_3960924_8	247490.KSU1_C0634	3.782e-58	218.0	COG0628@1|root,COG0628@2|Bacteria,2J2TA@203682|Planctomycetes	203682|Planctomycetes	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS3_k127_3960924_16	1379698.RBG1_1C00001G1452	1.475e-20	94.0	COG0011@1|root,COG0011@2|Bacteria	2|Bacteria	H	TIGRFAM Protein of	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
LZS3_k127_3960924_15	1042375.AFPL01000026_gene3631	6.528e-21	102.0	2DQ0H@1|root,33480@2|Bacteria,1R1FF@1224|Proteobacteria,1T50R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
LZS3_k127_3960924_6	1121943.KB899992_gene2278	7.386e-65	232.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XICI@135619|Oceanospirillales	135619|Oceanospirillales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04691,ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
LZS3_k127_3975183_8	234267.Acid_7718	1.606e-24	104.0	COG1193@1|root,COG1193@2|Bacteria,3Y2Z2@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
LZS3_k127_3975183_6	1499967.BAYZ01000154_gene1455	2.112e-43	169.0	COG1357@1|root,COG1357@2|Bacteria,2NPTJ@2323|unclassified Bacteria	2|Bacteria	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS3_k127_3975183_1	593750.Metfor_0262	3.361e-113	369.0	COG1533@1|root,arCOG01290@2157|Archaea,2Y1RJ@28890|Euryarchaeota,2NAHF@224756|Methanomicrobia	224756|Methanomicrobia	L	Pfam:Gp37_Gp68	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
LZS3_k127_3975183_7	240292.Ava_0171	1.069e-35	147.0	2BWMX@1|root,2ZIUW@2|Bacteria,1G304@1117|Cyanobacteria,1HSNA@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3975183_3	344747.PM8797T_03234	9.04e-69	243.0	COG2230@1|root,COG2230@2|Bacteria,2J0X9@203682|Planctomycetes	203682|Planctomycetes	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.103	ko:K05929	ko00564,map00564	-	R02037,R06868,R06869	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000	-	-	-	-
LZS3_k127_3975183_0	234267.Acid_2447	1.348e-122	402.0	COG3391@1|root,COG3391@2|Bacteria,3Y8A0@57723|Acidobacteria	57723|Acidobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS3_k127_3975183_5	641524.ADICYQ_5450	1.538e-48	185.0	COG3618@1|root,COG3618@2|Bacteria,4NHCW@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_3975183_4	641524.ADICYQ_5450	3.362e-51	193.0	COG3618@1|root,COG3618@2|Bacteria,4NHCW@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_3975183_2	309807.SRU_0977	9.027e-80	287.0	2AB2F@1|root,310G6@2|Bacteria,4PEZP@976|Bacteroidetes,1FJWS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3975183_11	1338011.BD94_0829	1.146e-06	61.0	COG4775@1|root,COG4775@2|Bacteria,4NE80@976|Bacteroidetes,1HXIH@117743|Flavobacteriia,34PXP@308865|Elizabethkingia	976|Bacteroidetes	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
LZS3_k127_3975183_10	639030.JHVA01000001_gene845	3.507e-21	100.0	COG1629@1|root,COG4771@2|Bacteria,3Y2ZK@57723|Acidobacteria,2JICG@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_4007017_0	383372.Rcas_2979	2.767e-257	802.0	COG0129@1|root,COG0129@2|Bacteria,2G67Z@200795|Chloroflexi,377Z0@32061|Chloroflexia	32061|Chloroflexia	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
LZS3_k127_4007017_1	204669.Acid345_1052	1.293e-157	523.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
LZS3_k127_4007017_5	204669.Acid345_1083	7.983e-46	171.0	COG2318@1|root,COG2318@2|Bacteria,3Y8H7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
LZS3_k127_4007017_6	204669.Acid345_1083	4.26e-40	157.0	COG2318@1|root,COG2318@2|Bacteria,3Y8H7@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
LZS3_k127_4007017_2	1042375.AFPL01000013_gene2466	5.042e-148	485.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,1RMR4@1236|Gammaproteobacteria,464HF@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
LZS3_k127_4007017_7	1121406.JAEX01000007_gene2380	3.023e-35	136.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,42WKN@68525|delta/epsilon subdivisions,2WRXH@28221|Deltaproteobacteria,2MCPQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
LZS3_k127_4007017_4	1121406.JAEX01000007_gene2379	1.355e-127	418.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,42NHC@68525|delta/epsilon subdivisions,2WJQJ@28221|Deltaproteobacteria,2MGAK@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
LZS3_k127_4007017_3	234267.Acid_0880	2.326e-134	443.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS3_k127_403554_1	1379698.RBG1_1C00001G1218	4.511e-71	252.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS3_k127_403554_3	401053.AciPR4_2718	9.032e-38	155.0	COG3710@1|root,COG3710@2|Bacteria,3Y7KB@57723|Acidobacteria,2JMW2@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
LZS3_k127_403554_2	234267.Acid_5749	5.377e-57	224.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
LZS3_k127_403554_4	240015.ACP_0451	5.215e-24	106.0	COG2963@1|root,COG2963@2|Bacteria,3Y92H@57723|Acidobacteria	57723|Acidobacteria	L	PFAM transposase IS3 IS911 family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
LZS3_k127_403554_0	240015.ACP_0450	2.09e-109	361.0	COG2801@1|root,COG2801@2|Bacteria,3Y6NP@57723|Acidobacteria,2JNG9@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_408908_4	1297569.MESS2_130038	1.839e-29	125.0	COG1848@1|root,COG1848@2|Bacteria,1NDJE@1224|Proteobacteria,2UHGN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_408908_3	234267.Acid_2157	1.392e-37	146.0	COG0802@1|root,COG0802@2|Bacteria,3Y4WF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0079, ATPase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
LZS3_k127_408908_0	1267535.KB906767_gene4930	5.041e-132	432.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS3_k127_408908_1	530564.Psta_4263	5.602e-44	179.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	psrP1	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHU_C,GSDH,Malectin
LZS3_k127_408908_2	2002.JOEQ01000011_gene3934	4.519e-38	152.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4EH55@85012|Streptosporangiales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903136	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS3_k127_4107197_8	234267.Acid_3850	1.869e-113	370.0	COG0107@1|root,COG0107@2|Bacteria,3Y2MG@57723|Acidobacteria	57723|Acidobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS3_k127_4107197_13	1267535.KB906767_gene5525	2.823e-71	248.0	COG0118@1|root,COG0118@2|Bacteria,3Y5DZ@57723|Acidobacteria,2JKDU@204432|Acidobacteriia	204432|Acidobacteriia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS3_k127_4107197_9	234267.Acid_3852	4.48e-97	322.0	COG0131@1|root,COG0131@2|Bacteria,3Y3DU@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
LZS3_k127_4107197_18	1267535.KB906767_gene5528	1.229e-54	201.0	COG0546@1|root,COG0546@2|Bacteria,3Y7JG@57723|Acidobacteria	57723|Acidobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K11777	-	-	-	-	ko00000	-	-	-	HAD_2
LZS3_k127_4107197_7	234267.Acid_3854	5.417e-116	384.0	COG0079@1|root,COG0079@2|Bacteria,3Y3M6@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_4107197_4	234267.Acid_3855	1.287e-164	527.0	COG0141@1|root,COG0141@2|Bacteria,3Y2N7@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
LZS3_k127_4107197_20	234267.Acid_3857	7.296e-47	174.0	COG0139@1|root,COG0139@2|Bacteria,3Y4SN@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	-	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
LZS3_k127_4107197_10	234267.Acid_6489	2.097e-88	300.0	COG1354@1|root,COG1354@2|Bacteria,3Y458@57723|Acidobacteria	57723|Acidobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
LZS3_k127_4107197_17	234267.Acid_6490	4.966e-65	231.0	COG1386@1|root,COG1386@2|Bacteria,3Y3E0@57723|Acidobacteria	57723|Acidobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
LZS3_k127_4107197_11	234267.Acid_6491	9.517e-78	267.0	COG1187@1|root,COG1187@2|Bacteria,3Y3CQ@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS3_k127_4107197_21	204669.Acid345_2337	2.6e-40	153.0	COG1832@1|root,COG1832@2|Bacteria,3Y566@57723|Acidobacteria,2JJFN@204432|Acidobacteriia	204432|Acidobacteriia	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
LZS3_k127_4107197_3	926549.KI421517_gene77	2.512e-218	691.0	COG1921@1|root,COG1921@2|Bacteria,4PN21@976|Bacteroidetes,47Y5Q@768503|Cytophagia	976|Bacteroidetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,Cys_Met_Meta_PP
LZS3_k127_4107197_6	234267.Acid_6258	1.801e-125	430.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K16648	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	DUF3367,PMT_2
LZS3_k127_4107197_5	1340493.JNIF01000003_gene1307	2.447e-151	490.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
LZS3_k127_4107197_12	234267.Acid_0159	1.39e-77	267.0	COG1707@1|root,COG1707@2|Bacteria,3Y6KK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	ko:K06862	-	-	-	-	ko00000	-	-	-	-
LZS3_k127_4107197_15	314230.DSM3645_22434	7.757e-66	237.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS3_k127_4107197_14	234267.Acid_7557	5.312e-67	238.0	COG3468@1|root,COG3468@2|Bacteria,3Y4NE@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4107197_1	234267.Acid_1640	1.115e-275	872.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
LZS3_k127_4107197_0	240015.ACP_2022	0.0	1247.0	COG1048@1|root,COG1048@2|Bacteria,3Y34Q@57723|Acidobacteria,2JHMV@204432|Acidobacteriia	204432|Acidobacteriia	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
LZS3_k127_4107197_16	204669.Acid345_0278	1.765e-65	235.0	COG1624@1|root,COG1624@2|Bacteria,3Y7NU@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
LZS3_k127_4107197_22	204669.Acid345_0277	8.164e-30	127.0	COG4856@1|root,COG4856@2|Bacteria,3Y8QK@57723|Acidobacteria	57723|Acidobacteria	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
LZS3_k127_4107197_19	1210884.HG799465_gene11606	2.261e-48	178.0	COG3153@1|root,COG3153@2|Bacteria,2IZPX@203682|Planctomycetes	203682|Planctomycetes	S	Acetyltransferase (GNAT) family	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
LZS3_k127_4107197_2	234267.Acid_1536	8.589e-270	850.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
LZS3_k127_4143789_1	1047013.AQSP01000140_gene2497	5.734e-116	393.0	COG2866@1|root,COG2866@2|Bacteria,2NQNH@2323|unclassified Bacteria	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
LZS3_k127_4143789_0	1267535.KB906767_gene820	5.023e-147	471.0	COG0214@1|root,COG0214@2|Bacteria,3Y3ST@57723|Acidobacteria,2JKN5@204432|Acidobacteriia	204432|Acidobacteriia	H	Belongs to the PdxS SNZ family	-	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
LZS3_k127_4143789_3	234267.Acid_0289	3.844e-68	237.0	COG0311@1|root,COG0311@2|Bacteria,3Y4GN@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
LZS3_k127_4143789_4	1340493.JNIF01000003_gene4617	2.088e-27	117.0	COG0394@1|root,COG0394@2|Bacteria,3Y8RC@57723|Acidobacteria	57723|Acidobacteria	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
LZS3_k127_4143789_2	234267.Acid_3817	3.159e-74	261.0	COG0583@1|root,COG0583@2|Bacteria,3Y74M@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS3_k127_416915_2	483219.LILAB_07305	1.956e-69	256.0	COG3291@1|root,COG3291@2|Bacteria,1QU15@1224|Proteobacteria,4336P@68525|delta/epsilon subdivisions,2WYD6@28221|Deltaproteobacteria,2YX7G@29|Myxococcales	28221|Deltaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_416915_1	234267.Acid_6284	1.597e-92	309.0	COG0745@1|root,COG0745@2|Bacteria	234267.Acid_6284|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_416915_3	767817.Desgi_4028	1.113e-55	210.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
LZS3_k127_416915_0	1267535.KB906767_gene4246	1.11e-98	339.0	COG3119@1|root,COG3119@2|Bacteria,3Y679@57723|Acidobacteria	57723|Acidobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
LZS3_k127_4180900_16	1267535.KB906767_gene3656	1.49e-21	101.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
LZS3_k127_4180900_15	234267.Acid_2675	9.643e-38	148.0	COG1943@1|root,COG1943@2|Bacteria,3Y8QI@57723|Acidobacteria	57723|Acidobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
LZS3_k127_4180900_18	1122169.AREN01000044_gene2480	1.313e-09	60.0	COG1943@1|root,COG1943@2|Bacteria,1QC63@1224|Proteobacteria,1T7V3@1236|Gammaproteobacteria,1JFWA@118969|Legionellales	118969|Legionellales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
LZS3_k127_4180900_7	234267.Acid_1598	3.388e-131	428.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	glmD	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
LZS3_k127_4180900_11	443144.GM21_2612	7.721e-97	323.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,43TJ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM DAHP synthetase I KDSA	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
LZS3_k127_4180900_2	1123371.ATXH01000022_gene976	4.914e-224	707.0	COG0504@1|root,COG0504@2|Bacteria,2GHMU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
LZS3_k127_4180900_8	234267.Acid_6217	9.154e-122	404.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
LZS3_k127_4180900_12	1340493.JNIF01000003_gene2459	6.421e-87	297.0	COG2304@1|root,COG2304@2|Bacteria,3Y483@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
LZS3_k127_4180900_17	1267535.KB906767_gene625	7.057e-20	93.0	2EKYQ@1|root,33EN7@2|Bacteria,3Y5T5@57723|Acidobacteria,2JK2W@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4180900_14	1121434.AULY01000009_gene1971	5.438e-48	191.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2M8K7@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_4180900_10	1232410.KI421413_gene649	1.63e-108	368.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,43SBG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
LZS3_k127_4180900_0	338963.Pcar_1714	0.0	1377.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,43S9Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
LZS3_k127_4180900_20	1132442.KB889752_gene344	9.716e-05	53.0	COG1349@1|root,COG1349@2|Bacteria,1V2NI@1239|Firmicutes,4HG3I@91061|Bacilli,1ZGG8@1386|Bacillus	91061|Bacilli	K	COG1349 Transcriptional regulators of sugar metabolism	ycnK	-	-	ko:K21601	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,NosL
LZS3_k127_4180900_1	1382359.JIAL01000001_gene807	1.351e-294	914.0	COG0481@1|root,COG0481@2|Bacteria,3Y3EX@57723|Acidobacteria,2JI4G@204432|Acidobacteriia	204432|Acidobacteriia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
LZS3_k127_4180900_6	1379698.RBG1_1C00001G0608	6.015e-135	457.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
LZS3_k127_4180900_3	234267.Acid_1915	4.569e-170	552.0	COG0539@1|root,COG0539@2|Bacteria,3Y3P3@57723|Acidobacteria	57723|Acidobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
LZS3_k127_4180900_9	861299.J421_4303	6.286e-109	366.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	gnl	GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
LZS3_k127_4180900_13	65393.PCC7424_2894	2.974e-70	247.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,3KGMC@43988|Cyanothece	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
LZS3_k127_4180900_5	234267.Acid_7476	5.561e-147	475.0	COG0381@1|root,COG0381@2|Bacteria,3Y50B@57723|Acidobacteria	57723|Acidobacteria	M	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS3_k127_4180900_4	1340493.JNIF01000003_gene3829	1.765e-163	552.0	COG1629@1|root,COG1629@2|Bacteria,3Y6CT@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_4262275_1	497964.CfE428DRAFT_2531	3.327e-172	554.0	COG1216@1|root,COG4976@1|root,COG1216@2|Bacteria,COG4976@2|Bacteria,46W0C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_4262275_7	1340493.JNIF01000003_gene4182	8.13e-90	303.0	COG1028@1|root,COG1028@2|Bacteria	1340493.JNIF01000003_gene4182|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4262275_9	886293.Sinac_4639	5.223e-77	267.0	COG1082@1|root,COG1082@2|Bacteria,2IZR0@203682|Planctomycetes	2|Bacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
LZS3_k127_4262275_4	497964.CfE428DRAFT_5616	3.992e-122	407.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DLH,DUF1929,Glyoxal_oxid_N
LZS3_k127_4262275_8	756272.Plabr_4452	1.037e-88	303.0	arCOG12117@1|root,2Z9N1@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3891
LZS3_k127_4262275_0	1267535.KB906767_gene4757	1.192e-200	632.0	COG2115@1|root,COG2115@2|Bacteria,3Y841@57723|Acidobacteria,2JNHR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the xylose isomerase family	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
LZS3_k127_4262275_6	234267.Acid_4805	2.349e-93	313.0	COG2120@1|root,COG2120@2|Bacteria,3Y3NP@57723|Acidobacteria	57723|Acidobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
LZS3_k127_4262275_12	1266909.AUAG01000014_gene2255	3.459e-14	74.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	DUF836,Thioredoxin
LZS3_k127_4262275_10	706587.Desti_0005	1.039e-64	228.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2MRXV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
LZS3_k127_4262275_2	234267.Acid_4808	4.409e-137	442.0	COG0524@1|root,COG0524@2|Bacteria,3Y659@57723|Acidobacteria	57723|Acidobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.184	ko:K18478	-	-	R10970	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
LZS3_k127_4262275_11	1128421.JAGA01000003_gene2786	1.529e-58	207.0	COG1881@1|root,COG1881@2|Bacteria,2NPMM@2323|unclassified Bacteria	2|Bacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
LZS3_k127_4262275_3	1123073.KB899243_gene509	1.04e-124	417.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1X944@135614|Xanthomonadales	135614|Xanthomonadales	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_4262275_5	1340493.JNIF01000003_gene1948	7.592e-102	341.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_4262275_14	935863.AWZR01000014_gene2989	5.475e-06	57.0	2EHSB@1|root,33BI2@2|Bacteria	2|Bacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
LZS3_k127_4262275_15	1303518.CCALI_00738	0.0001018	53.0	2EHSB@1|root,33BI2@2|Bacteria	2|Bacteria	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
LZS3_k127_4313002_4	1123278.KB893551_gene3661	1.691e-06	53.0	COG2271@1|root,COG2271@2|Bacteria,4NGCR@976|Bacteroidetes,47JNU@768503|Cytophagia	976|Bacteroidetes	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_4313002_2	1267535.KB906767_gene4262	2.056e-112	376.0	COG2271@1|root,COG2271@2|Bacteria,3Y6AJ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_4313002_0	1304275.C41B8_03591	1.666e-190	612.0	COG0165@1|root,COG0165@2|Bacteria,1MUB6@1224|Proteobacteria,1SM3E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Argininosuccinate lyase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	ASL_C2,Lyase_1
LZS3_k127_4313002_3	195250.CM001776_gene345	7.156e-42	175.0	COG2319@1|root,COG3064@1|root,COG2319@2|Bacteria,COG3064@2|Bacteria,1FZVW@1117|Cyanobacteria,1GZQ3@1129|Synechococcus	1117|Cyanobacteria	M	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
LZS3_k127_4313002_1	1267535.KB906767_gene5244	2.198e-156	506.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
LZS3_k127_4329902_1	234267.Acid_1908	3.119e-154	495.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,3Y339@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
LZS3_k127_4329902_2	251229.Chro_2173	4.435e-59	216.0	COG3386@1|root,COG3386@2|Bacteria,1G2S8@1117|Cyanobacteria,3VMV4@52604|Pleurocapsales	1117|Cyanobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
LZS3_k127_4329902_4	588581.Cpap_0488	1.121e-05	56.0	COG2159@1|root,COG2159@2|Bacteria,1TRU0@1239|Firmicutes,248VZ@186801|Clostridia	186801|Clostridia	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_4329902_3	1120936.KB907213_gene4680	5.17e-17	92.0	COG2159@1|root,COG2159@2|Bacteria,2H1B2@201174|Actinobacteria,4ENU3@85012|Streptosporangiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_4329902_0	234267.Acid_1817	1.226e-170	550.0	COG4206@1|root,COG4206@2|Bacteria,3Y8AK@57723|Acidobacteria	57723|Acidobacteria	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
LZS3_k127_4347761_3	234267.Acid_3783	5.986e-09	59.0	COG5010@1|root,COG5010@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K13486	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Acetyltransf_6,DUF1570,Response_reg,TPR_16,TPR_19
LZS3_k127_4347761_2	204669.Acid345_1954	1.777e-89	301.0	COG0177@1|root,COG0177@2|Bacteria,3Y3QD@57723|Acidobacteria,2JI6M@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
LZS3_k127_4347761_1	1123508.JH636443_gene4540	3.825e-98	335.0	28KEJ@1|root,2Z9XE@2|Bacteria,2IX1V@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4347761_0	1122137.AQXF01000004_gene1784	2.964e-184	591.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_4394250_0	234267.Acid_1189	7.732e-124	416.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_4394250_1	1267535.KB906767_gene4918	2.265e-113	384.0	COG1233@1|root,COG1233@2|Bacteria,3Y9B4@57723|Acidobacteria	57723|Acidobacteria	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
LZS3_k127_4394250_2	113395.AXAI01000006_gene1646	3.186e-35	138.0	COG0346@1|root,COG0346@2|Bacteria,1RG1A@1224|Proteobacteria,2U7AV@28211|Alphaproteobacteria,3JZ8P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_4400351_4	1340493.JNIF01000004_gene944	1.886e-12	75.0	COG4783@1|root,COG4783@2|Bacteria,3Y6B5@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_4400351_0	234267.Acid_0752	6.407e-41	156.0	COG0517@1|root,COG0517@2|Bacteria,3Y8IB@57723|Acidobacteria	57723|Acidobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_4400351_3	404380.Gbem_0454	9.732e-15	74.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,43VXN@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4400351_2	234267.Acid_0309	1.546e-22	101.0	COG1734@1|root,COG1734@2|Bacteria,3Y5PJ@57723|Acidobacteria	57723|Acidobacteria	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS3_k127_4400351_1	1267535.KB906767_gene4539	1.182e-32	135.0	COG2823@1|root,COG2823@2|Bacteria,3Y7ZV@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4420202_8	322710.Avin_05350	3.05e-09	68.0	COG3307@1|root,COG3307@2|Bacteria,1RBK5@1224|Proteobacteria,1S2Y8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS3_k127_4420202_6	749222.Nitsa_1720	2.432e-71	258.0	COG0438@1|root,COG0438@2|Bacteria,1PGU4@1224|Proteobacteria,43AB9@68525|delta/epsilon subdivisions,2YQX4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
LZS3_k127_4420202_4	1121904.ARBP01000015_gene188	2.155e-98	344.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,47JR5@768503|Cytophagia	976|Bacteroidetes	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
LZS3_k127_4420202_5	926569.ANT_26100	7.706e-78	273.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_4420202_1	670292.JH26_16730	9.852e-145	481.0	COG1541@1|root,COG1541@2|Bacteria,1R7WG@1224|Proteobacteria,2U4M0@28211|Alphaproteobacteria,1JWE6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
LZS3_k127_4420202_7	395495.Lcho_3510	3.719e-69	249.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2VIY4@28216|Betaproteobacteria,1KJZ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	TIGRFAM sugar transferase, PEP-CTERM system associated	wcaJ	-	2.7.8.40	ko:K21303	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3
LZS3_k127_4420202_2	240015.ACP_2205	1.766e-121	398.0	COG0010@1|root,COG0010@2|Bacteria,3Y46E@57723|Acidobacteria,2JIPY@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
LZS3_k127_4420202_0	886293.Sinac_7090	1.636e-169	565.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4420202_3	344747.PM8797T_04565	5.51e-111	372.0	COG0673@1|root,COG0673@2|Bacteria,2IXYP@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_4446396_7	234267.Acid_1761	1.663e-94	316.0	COG1355@1|root,COG1355@2|Bacteria,3Y5Z0@57723|Acidobacteria	57723|Acidobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
LZS3_k127_4446396_8	314230.DSM3645_07485	4.381e-69	246.0	COG0673@1|root,COG0673@2|Bacteria,2J216@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_4446396_3	1131269.AQVV01000001_gene1356	2.933e-164	531.0	COG0471@1|root,COG0471@2|Bacteria	2|Bacteria	P	metal ion transport	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS3_k127_4446396_10	234267.Acid_4046	7.323e-66	237.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_4046|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4446396_6	234267.Acid_1310	1.264e-112	370.0	COG0382@1|root,COG0382@2|Bacteria,3Y3CW@57723|Acidobacteria	57723|Acidobacteria	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS3_k127_4446396_11	1123278.KB893544_gene4865	8.385e-06	50.0	COG5450@1|root,COG5450@2|Bacteria,4NXNG@976|Bacteroidetes,47SQW@768503|Cytophagia	976|Bacteroidetes	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
LZS3_k127_4446396_1	234267.Acid_1309	9.648e-196	616.0	COG1060@1|root,COG1060@2|Bacteria,3Y331@57723|Acidobacteria	57723|Acidobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
LZS3_k127_4446396_5	1267535.KB906767_gene801	4.921e-141	466.0	COG4992@1|root,COG4992@2|Bacteria,3Y36P@57723|Acidobacteria,2JISH@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_4446396_2	240016.ABIZ01000001_gene1332	2.66e-185	590.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_4446396_9	1280954.HPO_17776	3.294e-66	242.0	COG0520@1|root,COG0520@2|Bacteria,1R6VV@1224|Proteobacteria,2VFZ3@28211|Alphaproteobacteria,43ZAX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS3_k127_4446396_4	234267.Acid_1144	3.302e-153	501.0	COG3391@1|root,COG3391@2|Bacteria,3Y98W@57723|Acidobacteria	57723|Acidobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS3_k127_4446396_0	608538.HTH_0199	6.67e-204	644.0	COG0422@1|root,COG0422@2|Bacteria,2G3RS@200783|Aquificae	200783|Aquificae	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
LZS3_k127_4448275_1	1123248.KB893325_gene1154	7.144e-70	241.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	2|Bacteria	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
LZS3_k127_4448275_4	639030.JHVA01000001_gene2970	1.543e-52	197.0	COG1028@1|root,COG1028@2|Bacteria,3Y2YB@57723|Acidobacteria,2JII9@204432|Acidobacteriia	204432|Acidobacteriia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_4448275_3	208439.AJAP_07130	9.123e-66	231.0	COG2043@1|root,COG2043@2|Bacteria,2ISFS@201174|Actinobacteria,4EB4E@85010|Pseudonocardiales	201174|Actinobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
LZS3_k127_4448275_5	565045.NOR51B_2532	2.913e-49	184.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,1S9IZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP	acpH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576	3.1.4.14	ko:K08682	ko00770,map00770	-	R01623	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426	ACP_PD
LZS3_k127_4448275_2	497964.CfE428DRAFT_6276	1.33e-68	259.0	COG2755@1|root,COG2755@2|Bacteria,46SVE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS3_k127_4448275_7	1449063.JMLS01000009_gene2209	3.145e-13	83.0	28H6M@1|root,2Z7J0@2|Bacteria	2|Bacteria	G	Pectate lyase	pelY	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase_2
LZS3_k127_4448275_0	234267.Acid_7263	0.0	1341.0	COG0178@1|root,COG0178@2|Bacteria,3Y3G9@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS3_k127_4448275_8	251221.35211983	6.735e-05	46.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_4484339_1	234267.Acid_4059	4.136e-136	449.0	COG2010@1|root,COG2010@2|Bacteria,3Y6T1@57723|Acidobacteria	57723|Acidobacteria	C	cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
LZS3_k127_4484339_0	269799.Gmet_2332	1.387e-165	531.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42N6P@68525|delta/epsilon subdivisions,2WJVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_4484339_2	1187848.AJYQ01000004_gene177	6.079e-64	229.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,1RQJT@1236|Gammaproteobacteria,1XY81@135623|Vibrionales	135623|Vibrionales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_4484339_3	397291.C804_00527	3.079e-21	102.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,27J8X@186928|unclassified Lachnospiraceae	186801|Clostridia	Q	AMP-binding enzyme	bacA	-	-	ko:K04784,ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,Thioesterase
LZS3_k127_4488793_16	1267535.KB906767_gene272	1.136e-57	207.0	2DG4T@1|root,2ZUHN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4488793_27	69395.JQLZ01000002_gene1490	3.458e-13	83.0	COG5010@1|root,COG5010@2|Bacteria,1R7S3@1224|Proteobacteria,2U39S@28211|Alphaproteobacteria,2KHNH@204458|Caulobacterales	204458|Caulobacterales	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570
LZS3_k127_4488793_6	1267535.KB906767_gene2591	1.153e-120	397.0	COG4106@1|root,COG4106@2|Bacteria,3Y6KU@57723|Acidobacteria	57723|Acidobacteria	S	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
LZS3_k127_4488793_24	1121015.N789_04820	2.46e-19	97.0	COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,1SCJF@1236|Gammaproteobacteria,1X7ZV@135614|Xanthomonadales	135614|Xanthomonadales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
LZS3_k127_4488793_12	1122222.AXWR01000029_gene2235	1.289e-68	240.0	COG0521@1|root,COG0521@2|Bacteria,1WIRM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Molybdenum cofactor biosynthesis protein B	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
LZS3_k127_4488793_11	234267.Acid_2012	1.227e-87	304.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	sumf2	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_11,Methyltransf_14,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS3_k127_4488793_13	234267.Acid_2011	5.355e-67	234.0	COG0325@1|root,COG0325@2|Bacteria,3Y4CY@57723|Acidobacteria	57723|Acidobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
LZS3_k127_4488793_15	234267.Acid_7330	2.684e-58	214.0	COG0125@1|root,COG0125@2|Bacteria,3Y562@57723|Acidobacteria	57723|Acidobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS3_k127_4488793_9	234267.Acid_7331	1.807e-89	309.0	COG0470@1|root,COG0470@2|Bacteria,3Y6V7@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
LZS3_k127_4488793_22	234267.Acid_0132	5.247e-31	128.0	COG1923@1|root,COG1923@2|Bacteria,3Y5JI@57723|Acidobacteria	57723|Acidobacteria	S	Hfq protein	-	-	-	-	-	-	-	-	-	-	-	-	Hfq
LZS3_k127_4488793_4	1340493.JNIF01000003_gene2091	1.877e-167	546.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y708@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
LZS3_k127_4488793_19	1340493.JNIF01000003_gene3836	1.531e-38	158.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
LZS3_k127_4488793_5	234267.Acid_0796	1.418e-131	438.0	COG0568@1|root,COG0568@2|Bacteria,3Y6Z7@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 3	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_4488793_18	391624.OIHEL45_16561	1.013e-40	161.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,2U683@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRC
LZS3_k127_4488793_26	575540.Isop_1163	3.199e-13	83.0	COG0366@1|root,COG0438@1|root,COG3115@1|root,COG0366@2|Bacteria,COG0438@2|Bacteria,COG3115@2|Bacteria,2IYAN@203682|Planctomycetes	203682|Planctomycetes	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
LZS3_k127_4488793_2	1121904.ARBP01000008_gene3234	2.398e-188	608.0	COG5492@1|root,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,47TBW@768503|Cytophagia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
LZS3_k127_4488793_10	344747.PM8797T_14519	5.943e-88	303.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
LZS3_k127_4488793_1	234267.Acid_7662	5.903e-201	646.0	COG0160@1|root,COG0160@2|Bacteria,3Y4EV@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.55	ko:K00823,ko:K15372	ko00250,ko00410,ko00430,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00430,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R01684	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_4488793_20	234267.Acid_7737	3.255e-36	142.0	COG0662@1|root,COG0662@2|Bacteria,3Y7HE@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_4488793_14	234267.Acid_6149	3.817e-62	218.0	COG0251@1|root,COG0251@2|Bacteria,3Y4PU@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
LZS3_k127_4488793_7	401053.AciPR4_2596	2.464e-107	376.0	COG1363@1|root,COG1363@2|Bacteria,3Y2Y3@57723|Acidobacteria,2JKCI@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
LZS3_k127_4488793_0	1340493.JNIF01000003_gene2091	4.164e-240	770.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y708@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
LZS3_k127_4488793_8	1267535.KB906767_gene544	5.338e-98	355.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_4488793_17	861299.J421_0153	1.103e-43	175.0	COG4409@1|root,COG4409@2|Bacteria,1ZUI0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4488793_25	886293.Sinac_3156	1.29e-18	93.0	COG0526@1|root,COG0526@2|Bacteria,2J0JE@203682|Planctomycetes	203682|Planctomycetes	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
LZS3_k127_4488793_23	234267.Acid_5392	8.665e-22	100.0	2CTSB@1|root,32SU2@2|Bacteria,3Y567@57723|Acidobacteria	57723|Acidobacteria	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_4488793_29	1267533.KB906734_gene4216	4.15e-06	51.0	arCOG13401@1|root,33MMV@2|Bacteria,3Y5TE@57723|Acidobacteria,2JNR5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
LZS3_k127_4488793_3	1340493.JNIF01000004_gene556	6.051e-171	544.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_4535297_2	671143.DAMO_0264	5.398e-55	211.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606,ko:K20997	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
LZS3_k127_4535297_1	234267.Acid_6617	1.829e-117	404.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
LZS3_k127_4535297_3	234267.Acid_6616	2.203e-41	165.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4535297_0	234267.Acid_2710	6.998e-123	421.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,3Y2UJ@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,YfiO
LZS3_k127_4535297_4	234267.Acid_2708	1.029e-33	135.0	COG4221@1|root,COG4221@2|Bacteria,3Y4DX@57723|Acidobacteria	57723|Acidobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_4572591_8	234267.Acid_7651	1.53e-28	128.0	COG1637@1|root,COG1637@2|Bacteria,3Y5TD@57723|Acidobacteria	57723|Acidobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	NucS
LZS3_k127_4572591_7	1173023.KE650771_gene5116	6.065e-41	166.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS3_k127_4572591_2	1487953.JMKF01000028_gene1253	4.882e-166	540.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H9JN@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GAF,GGDEF,PAS_3,PAS_9,Response_reg
LZS3_k127_4572591_4	1267535.KB906767_gene2719	6.996e-114	395.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.102	ko:K06978,ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	AXE1,Big_5,LTD,Peptidase_S9,Tannase
LZS3_k127_4572591_0	1267535.KB906767_gene4970	0.0	1270.0	COG0653@1|root,COG0653@2|Bacteria,3Y34P@57723|Acidobacteria,2JHSP@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
LZS3_k127_4572591_6	234267.Acid_4488	1.484e-52	199.0	29QWH@1|root,30BWY@2|Bacteria,3Y4SG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4572591_3	1198114.AciX9_2792	5.534e-133	439.0	COG0469@1|root,COG0469@2|Bacteria,3Y36V@57723|Acidobacteria,2JHY5@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
LZS3_k127_4572591_5	316274.Haur_4323	1.758e-97	333.0	COG0451@1|root,COG0451@2|Bacteria,2GBWQ@200795|Chloroflexi,3774S@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_4572591_1	756067.MicvaDRAFT_2506	0.0	1202.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H9T8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
LZS3_k127_4572626_0	221288.JH992901_gene3910	0.0	1144.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIN@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,TauD,Thioesterase
LZS3_k127_4609187_0	745411.B3C1_15919	2.022e-142	460.0	COG1680@1|root,COG1680@2|Bacteria,1RIU7@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_4609187_4	329726.AM1_3279	8.758e-29	118.0	2CSD0@1|root,32SQY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4609187_3	1249997.JHZW01000003_gene2076	9.647e-45	166.0	2DSUT@1|root,33HH9@2|Bacteria,4PQ2D@976|Bacteroidetes,1IKYU@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4609187_2	391625.PPSIR1_30656	4.126e-57	208.0	COG0500@1|root,COG2226@2|Bacteria,1PARM@1224|Proteobacteria,4358M@68525|delta/epsilon subdivisions,2WZJQ@28221|Deltaproteobacteria,2Z29Z@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_4609187_1	1120983.KB894574_gene795	7.342e-97	320.0	COG0695@1|root,COG0695@2|Bacteria,1MXQW@1224|Proteobacteria,2TT7R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	COG0695 glutaredoxin and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin,MauE
LZS3_k127_460932_4	1121035.AUCH01000009_gene882	1.913e-17	89.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,2VI8F@28216|Betaproteobacteria,2KW3F@206389|Rhodocyclales	206389|Rhodocyclales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS3_k127_460932_6	204669.Acid345_0079	1.474e-05	53.0	COG0265@1|root,COG0265@2|Bacteria,3Y7Q3@57723|Acidobacteria,2JMRR@204432|Acidobacteriia	204432|Acidobacteriia	O	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
LZS3_k127_460932_5	1121022.ABENE_07780	1.509e-09	68.0	2EJVC@1|root,33DK2@2|Bacteria,1N9WN@1224|Proteobacteria,2UHCD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_460932_0	502025.Hoch_1944	2.15e-217	685.0	COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,42N8Z@68525|delta/epsilon subdivisions,2WTR2@28221|Deltaproteobacteria,2YU56@29|Myxococcales	28221|Deltaproteobacteria	H	AbgT putative transporter family	abgT	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
LZS3_k127_460932_3	861299.J421_5632	3.513e-27	117.0	COG2010@1|root,COG2010@2|Bacteria,1ZU5I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS3_k127_460932_1	234267.Acid_2703	8.898e-131	434.0	28N30@1|root,2ZB8S@2|Bacteria,3Y2XH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_460932_2	1340493.JNIF01000003_gene1910	2.46e-35	143.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,rRNA_methylase
LZS3_k127_4615979_27	35128.Thaps32882	1.358e-75	264.0	COG4948@1|root,2QRKX@2759|Eukaryota,2XFGI@2836|Bacillariophyta	2836|Bacillariophyta	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_4615979_37	420324.KI911965_gene470	4.99e-27	123.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2TRE1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS3_k127_4615979_23	768671.ThimaDRAFT_3236	2.003e-89	307.0	COG1215@1|root,COG1215@2|Bacteria,1QUG1@1224|Proteobacteria,1RZH7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_4615979_40	1340493.JNIF01000003_gene3542	6.438e-19	91.0	2C9TJ@1|root,2ZFZD@2|Bacteria,3Y970@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4615979_9	1340493.JNIF01000003_gene2437	6.12e-154	497.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
LZS3_k127_4615979_31	234267.Acid_7422	4.911e-57	202.0	COG0615@1|root,COG0615@2|Bacteria,3Y5F4@57723|Acidobacteria	57723|Acidobacteria	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
LZS3_k127_4615979_0	639030.JHVA01000001_gene2701	0.0	1031.0	COG1197@1|root,COG1197@2|Bacteria,3Y3IE@57723|Acidobacteria,2JIHQ@204432|Acidobacteriia	204432|Acidobacteriia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
LZS3_k127_4615979_21	324057.Pjdr2_0782	2.371e-99	340.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,26VB1@186822|Paenibacillaceae	91061|Bacilli	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_4615979_32	266117.Rxyl_2043	9.851e-46	167.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
LZS3_k127_4615979_35	1304284.L21TH_0963	2.403e-33	145.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS3_k127_4615979_15	234267.Acid_0726	2.87e-122	400.0	COG0303@1|root,COG0303@2|Bacteria,3Y6V2@57723|Acidobacteria	57723|Acidobacteria	H	'Molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4615979_25	234267.Acid_0724	1.251e-85	291.0	COG0548@1|root,COG0548@2|Bacteria,3Y2IF@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
LZS3_k127_4615979_14	234267.Acid_0723	6.031e-138	447.0	COG0002@1|root,COG0002@2|Bacteria,3Y450@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS3_k127_4615979_34	234267.Acid_4928	1.024e-34	142.0	29ZWG@1|root,30MXU@2|Bacteria,3Y5VK@57723|Acidobacteria	57723|Acidobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS3_k127_4615979_19	344747.PM8797T_16665	5.777e-105	360.0	COG1520@1|root,COG1520@2|Bacteria,2J2HQ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_4615979_12	530564.Psta_3677	2.375e-142	489.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IYJR@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2
LZS3_k127_4615979_17	1121481.AUAS01000018_gene474	1.178e-107	364.0	COG3964@1|root,COG3964@2|Bacteria,4NI4W@976|Bacteroidetes,47M3B@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_4615979_28	1340493.JNIF01000003_gene2855	2.276e-72	256.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Copper-bind,Cytochrom_C,Laminin_G_3
LZS3_k127_4615979_5	234267.Acid_7184	1.181e-181	587.0	COG1044@1|root,COG1044@2|Bacteria,3Y2ZS@57723|Acidobacteria	57723|Acidobacteria	M	SpoIVB peptidase S55	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
LZS3_k127_4615979_2	234267.Acid_7185	9.514e-204	658.0	COG3386@1|root,COG3386@2|Bacteria,3Y2G7@57723|Acidobacteria	57723|Acidobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4615979_41	572546.Arcpr_1056	1.355e-14	83.0	COG1184@1|root,arCOG01125@2157|Archaea	2157|Archaea	J	Belongs to the eIF-2B alpha beta delta subunits family	-	-	-	ko:K03680	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	IF-2B
LZS3_k127_4615979_16	945713.IALB_1976	2.268e-114	396.0	COG0348@1|root,COG0492@1|root,COG0348@2|Bacteria,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	trxB_2	-	1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Fer4_5,Fer4_9,Pyr_redox_3
LZS3_k127_4615979_13	570952.ATVH01000019_gene835	4.661e-139	456.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2U3S7@28211|Alphaproteobacteria,2JR3P@204441|Rhodospirillales	204441|Rhodospirillales	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS3_k127_4615979_8	1173026.Glo7428_4012	2.526e-163	527.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
LZS3_k127_4615979_4	234267.Acid_1559	3.128e-191	606.0	COG0498@1|root,COG0498@2|Bacteria,3Y3G4@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_4615979_26	331869.BAL199_06519	3.126e-84	286.0	COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2TTDD@28211|Alphaproteobacteria,4BT86@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA_1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
LZS3_k127_4615979_30	1177181.T9A_02805	8.986e-64	225.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1XKH1@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	ApbA,ApbA_C,SelR
LZS3_k127_4615979_36	1340493.JNIF01000003_gene3797	1.618e-27	115.0	COG0745@1|root,COG0745@2|Bacteria,3Y55U@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
LZS3_k127_4615979_7	1340493.JNIF01000003_gene2091	4.301e-168	544.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y708@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
LZS3_k127_4615979_33	639030.JHVA01000001_gene3791	4.987e-42	166.0	COG2010@1|root,COG2010@2|Bacteria,3Y7NP@57723|Acidobacteria,2JMS9@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_4615979_6	234267.Acid_0526	5.614e-170	544.0	COG0460@1|root,COG0460@2|Bacteria,3Y2VY@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
LZS3_k127_4615979_1	234267.Acid_6602	1.778e-237	758.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,3Y2QH@57723|Acidobacteria	57723|Acidobacteria	M	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
LZS3_k127_4615979_11	344747.PM8797T_00362	6.714e-146	479.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	-	-	-	-	-	-	-	-	-	-	PHP
LZS3_k127_4615979_18	344747.PM8797T_06275	2.25e-106	354.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
LZS3_k127_4615979_43	1173022.Cri9333_1432	0.0001367	48.0	COG2402@1|root,COG2402@2|Bacteria,1G63K@1117|Cyanobacteria,1HHI5@1150|Oscillatoriales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
LZS3_k127_4615979_22	1123242.JH636434_gene3868	1.282e-98	338.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene3868|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4615979_29	1163409.UUA_06454	5.947e-65	224.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,1S69N@1236|Gammaproteobacteria,1X6M5@135614|Xanthomonadales	135614|Xanthomonadales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
LZS3_k127_4615979_3	479434.Sthe_2955	9.091e-194	619.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_4615979_39	234267.Acid_6643	1.808e-19	93.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ANAPC5,TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
LZS3_k127_4615979_42	1120950.KB892707_gene4612	2.65e-11	76.0	COG2309@1|root,COG2309@2|Bacteria,2IDIQ@201174|Actinobacteria	201174|Actinobacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4615979_10	1267535.KB906767_gene2670	1.026e-146	492.0	COG4485@1|root,COG4485@2|Bacteria,3Y74P@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS3_k127_4615979_24	1123242.JH636434_gene3868	2.126e-89	312.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene3868|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4615979_20	1123242.JH636434_gene5302	8.719e-105	360.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4628785_1	234267.Acid_0872	5.346e-79	282.0	COG1629@1|root,COG4771@2|Bacteria,3Y2QR@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_4628785_0	756272.Plabr_1845	6.657e-107	363.0	COG2358@1|root,COG5493@1|root,COG2358@2|Bacteria,COG5493@2|Bacteria,2IY5Z@203682|Planctomycetes	203682|Planctomycetes	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
LZS3_k127_4636824_11	313624.NSP_12230	3.025e-69	238.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1HMIT@1161|Nostocales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS3_k127_4636824_13	326423.RBAM_006060	2.596e-19	99.0	COG0697@1|root,COG0697@2|Bacteria,1UH2I@1239|Firmicutes,4HCFV@91061|Bacilli,1ZCXY@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	gmT1	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_4636824_9	697282.Mettu_2234	1.224e-71	263.0	COG0491@1|root,COG0491@2|Bacteria,1R6GR@1224|Proteobacteria,1SHXM@1236|Gammaproteobacteria,1XEX1@135618|Methylococcales	135618|Methylococcales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_4636824_4	641524.ADICYQ_2511	1.241e-138	458.0	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
LZS3_k127_4636824_0	886293.Sinac_1153	0.0	1103.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
LZS3_k127_4636824_2	886293.Sinac_1154	1.346e-236	738.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
LZS3_k127_4636824_3	886293.Sinac_1155	4.375e-183	587.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
LZS3_k127_4636824_6	204669.Acid345_3040	2.437e-127	422.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS3_k127_4636824_1	1340493.JNIF01000003_gene1861	8.395e-246	790.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
LZS3_k127_4636824_7	1340493.JNIF01000003_gene3435	7.106e-124	407.0	COG1312@1|root,COG1312@2|Bacteria,3Y6UB@57723|Acidobacteria	57723|Acidobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
LZS3_k127_4636824_5	1123242.JH636435_gene2134	1.609e-130	433.0	COG1914@1|root,COG1914@2|Bacteria,2IYEM@203682|Planctomycetes	2|Bacteria	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4636824_12	706587.Desti_1672	1.14e-44	168.0	COG0432@1|root,COG0432@2|Bacteria,1N5SN@1224|Proteobacteria,42SJC@68525|delta/epsilon subdivisions,2WP9F@28221|Deltaproteobacteria,2MRXI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS3_k127_4636824_8	1340493.JNIF01000003_gene3299	5.815e-91	314.0	COG2064@1|root,COG2064@2|Bacteria,3Y4FI@57723|Acidobacteria	57723|Acidobacteria	NU	type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS3_k127_4636824_10	1340493.JNIF01000003_gene3298	1.398e-69	239.0	COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria	57723|Acidobacteria	U	type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS3_k127_4669970_54	234267.Acid_3850	1.698e-20	91.0	COG0107@1|root,COG0107@2|Bacteria,3Y2MG@57723|Acidobacteria	57723|Acidobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS3_k127_4669970_52	1128421.JAGA01000002_gene563	8.651e-26	113.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS3_k127_4669970_22	1267535.KB906767_gene5523	1.869e-91	310.0	COG0106@1|root,COG0106@2|Bacteria,3Y4TG@57723|Acidobacteria,2JKDT@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
LZS3_k127_4669970_50	234267.Acid_1164	5.161e-29	120.0	COG1734@1|root,COG1734@2|Bacteria,3Y5PJ@57723|Acidobacteria	57723|Acidobacteria	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS3_k127_4669970_39	234267.Acid_2193	1.396e-48	182.0	COG1595@1|root,COG1595@2|Bacteria,3Y863@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_4669970_53	234267.Acid_2192	6.507e-23	109.0	COG4944@1|root,COG4944@2|Bacteria	2|Bacteria	K	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
LZS3_k127_4669970_62	203122.Sde_0090	3.884e-06	52.0	COG1225@1|root,COG1225@2|Bacteria,1MZN4@1224|Proteobacteria,1SG3M@1236|Gammaproteobacteria,46CDH@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_4669970_49	745014.OMB55_00013700	5.586e-31	132.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
LZS3_k127_4669970_16	448385.sce5875	1.3e-106	354.0	COG0491@1|root,COG0491@2|Bacteria,1PJNG@1224|Proteobacteria,437NT@68525|delta/epsilon subdivisions,2X2X1@28221|Deltaproteobacteria,2YZNC@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
LZS3_k127_4669970_17	234267.Acid_5905	4.83e-101	336.0	COG1082@1|root,COG1082@2|Bacteria,3Y7EJ@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_4669970_65	105425.BBPL01000009_gene1402	0.0008567	50.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,2NHUJ@228398|Streptacidiphilus	201174|Actinobacteria	S	YceI-like domain	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
LZS3_k127_4669970_19	1340493.JNIF01000003_gene2611	7.333e-101	337.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_4669970_46	314230.DSM3645_07450	3.569e-35	141.0	COG0727@1|root,COG0727@2|Bacteria,2IZU5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
LZS3_k127_4669970_0	1267535.KB906767_gene604	0.0	1581.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,3Y37Y@57723|Acidobacteria,2JI9E@204432|Acidobacteriia	204432|Acidobacteriia	E	Vitamin B12 dependent methionine synthase activation	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS3_k127_4669970_5	1267535.KB906767_gene3137	1.482e-198	647.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
LZS3_k127_4669970_57	1047013.AQSP01000088_gene1637	1.656e-14	77.0	COG2026@1|root,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
LZS3_k127_4669970_26	471854.Dfer_0652	1.647e-80	284.0	28KEJ@1|root,2Z9QB@2|Bacteria,4P1U9@976|Bacteroidetes,47TF2@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4669970_45	234267.Acid_2228	5.893e-38	153.0	COG3427@1|root,COG3427@2|Bacteria	2|Bacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
LZS3_k127_4669970_30	234267.Acid_2227	6.501e-75	261.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS3_k127_4669970_2	644966.Tmar_0545	9.449e-253	804.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain	-	-	1.17.1.4,1.2.5.3	ko:K03520,ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
LZS3_k127_4669970_29	234267.Acid_2225	5.131e-75	256.0	COG2080@1|root,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	coxS	-	1.2.5.3,1.3.99.16	ko:K03518,ko:K07302,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
LZS3_k127_4669970_1	234267.Acid_7927	2.7e-321	1009.0	COG0365@1|root,COG0365@2|Bacteria,3Y39K@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS3_k127_4669970_34	1286106.MPL1_06074	1.778e-62	225.0	COG0683@1|root,COG0683@2|Bacteria,1MWGW@1224|Proteobacteria,1RQ5G@1236|Gammaproteobacteria,461M9@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
LZS3_k127_4669970_15	1026882.MAMP_01710	9.912e-111	371.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RQZK@1236|Gammaproteobacteria,460F7@72273|Thiotrichales	72273|Thiotrichales	S	PQQ-dependent catabolism-associated beta-propeller protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
LZS3_k127_4669970_31	530564.Psta_3944	1.432e-73	261.0	COG1858@1|root,COG1858@2|Bacteria,2IY7G@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS3_k127_4669970_11	1267535.KB906767_gene3469	5.752e-160	515.0	COG0183@1|root,COG0183@2|Bacteria,3Y2U4@57723|Acidobacteria,2JIS1@204432|Acidobacteriia	204432|Acidobacteriia	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_4669970_6	1267535.KB906767_gene3470	3.837e-191	613.0	COG1960@1|root,COG1960@2|Bacteria,3Y2NA@57723|Acidobacteria,2JII2@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_4669970_42	1382359.JIAL01000001_gene206	1.929e-39	156.0	COG4639@1|root,COG4639@2|Bacteria,3Y3YS@57723|Acidobacteria,2JI4H@204432|Acidobacteriia	204432|Acidobacteriia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
LZS3_k127_4669970_33	1340493.JNIF01000004_gene504	4.901e-68	239.0	COG0705@1|root,COG0705@2|Bacteria,3Y45U@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS3_k127_4669970_58	234267.Acid_1010	4.594e-13	71.0	COG1826@1|root,COG1826@2|Bacteria,3Y5V7@57723|Acidobacteria	57723|Acidobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
LZS3_k127_4669970_48	1267535.KB906767_gene3018	7.302e-32	127.0	COG0776@1|root,COG0776@2|Bacteria,3Y5E1@57723|Acidobacteria,2JJN0@204432|Acidobacteriia	204432|Acidobacteriia	L	Bacterial DNA-binding protein	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS3_k127_4669970_8	234267.Acid_0346	2.141e-175	561.0	COG1206@1|root,COG1206@2|Bacteria,3Y2KD@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
LZS3_k127_4669970_24	234267.Acid_0347	7.866e-84	291.0	COG4974@1|root,COG4974@2|Bacteria,3Y2VX@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the 'phage' integrase family. XerC subfamily	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS3_k127_4669970_12	1123242.JH636435_gene2922	2.401e-148	481.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_4669970_7	234267.Acid_3181	1.352e-185	592.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,3Y4W1@57723|Acidobacteria	57723|Acidobacteria	H	synthase	-	-	2.1.1.107,4.2.1.75	ko:K01719,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
LZS3_k127_4669970_21	1340493.JNIF01000004_gene762	1.237e-92	314.0	COG1879@1|root,COG1879@2|Bacteria,3Y872@57723|Acidobacteria	57723|Acidobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
LZS3_k127_4669970_64	234267.Acid_7411	0.0004181	48.0	28WCX@1|root,2ZID8@2|Bacteria,3Y8ZH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4669970_32	1120965.AUBV01000006_gene2233	1.725e-70	249.0	COG2518@1|root,COG2518@2|Bacteria,4NMTP@976|Bacteroidetes,47MH9@768503|Cytophagia	976|Bacteroidetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS3_k127_4669970_41	927677.ALVU02000001_gene1596	1.224e-47	175.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria	1117|Cyanobacteria	J	translation initiation inhibitor, yjgF family	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
LZS3_k127_4669970_38	1123023.JIAI01000011_gene8860	8.421e-52	193.0	COG1225@1|root,COG1225@2|Bacteria,2H4Y3@201174|Actinobacteria	201174|Actinobacteria	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
LZS3_k127_4669970_10	1340493.JNIF01000003_gene2091	3.498e-162	530.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,3Y708@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
LZS3_k127_4669970_44	1340493.JNIF01000003_gene3836	3.686e-38	156.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria	2|Bacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.2.9,1.1.5.5,1.1.9.1,1.17.2.2	ko:K00114,ko:K17760,ko:K20936,ko:K21676,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
LZS3_k127_4669970_28	266117.Rxyl_2097	3.182e-76	265.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4CPC0@84995|Rubrobacteria	84995|Rubrobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
LZS3_k127_4669970_63	529818.AMSG_06255T0	8.98e-06	54.0	2CCHR@1|root,2SX87@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4669970_13	1267535.KB906767_gene4810	3.142e-146	475.0	COG0673@1|root,COG0673@2|Bacteria,3Y2KV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_4669970_36	215803.DB30_4653	8.728e-56	198.0	COG0662@1|root,COG0662@2|Bacteria,1N1T5@1224|Proteobacteria,42V1T@68525|delta/epsilon subdivisions,2WRU3@28221|Deltaproteobacteria,2YVWP@29|Myxococcales	28221|Deltaproteobacteria	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_4669970_3	234267.Acid_2315	5.762e-246	791.0	COG2120@1|root,COG2120@2|Bacteria,3Y3BV@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_4669970_25	234267.Acid_3878	2.237e-83	282.0	COG1045@1|root,COG1045@2|Bacteria,3Y4HF@57723|Acidobacteria	57723|Acidobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
LZS3_k127_4669970_47	645991.Sgly_0859	9.745e-33	141.0	COG0535@1|root,COG0535@2|Bacteria,1UXWS@1239|Firmicutes,247NG@186801|Clostridia	186801|Clostridia	C	Radical SAM	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
LZS3_k127_4669970_51	234267.Acid_4588	5.814e-27	118.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77,4.6.1.17	ko:K03637,ko:K03752,ko:K13818	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372,R11581	RC03425	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
LZS3_k127_4669970_9	278963.ATWD01000001_gene2409	8.114e-163	523.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria,2JI6Q@204432|Acidobacteriia	57723|Acidobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	-	-	-	-	-	-	-	-	-	-	Enolase_C,Enolase_N
LZS3_k127_4669970_43	234267.Acid_6515	4.194e-39	166.0	COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria,3Y2EZ@57723|Acidobacteria	2|Bacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF11,DUF4347,DUF5122,He_PIG,SBBP
LZS3_k127_4669970_61	218851.Aquca_002_00329.1	7.405e-07	62.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37MB0@33090|Viridiplantae,3GFCB@35493|Streptophyta	35493|Streptophyta	O	Belongs to the peptidase M10A family	-	-	-	ko:K08002,ko:K08006	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
LZS3_k127_4669970_4	1340493.JNIF01000003_gene1861	7.224e-241	774.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_dep_Rec
LZS3_k127_4669970_20	234267.Acid_5311	6.224e-95	318.0	28M4B@1|root,2ZAI9@2|Bacteria,3Y3NA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4669970_14	234267.Acid_0426	1.579e-120	409.0	COG3829@1|root,COG3829@2|Bacteria,3Y988@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
LZS3_k127_4669970_27	857087.Metme_4431	8.121e-78	274.0	COG2203@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,1RZAF@1236|Gammaproteobacteria,1XFZE@135618|Methylococcales	1236|Gammaproteobacteria	T	PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA_2,PAS_4,PAS_9
LZS3_k127_4669970_40	234267.Acid_5458	1.905e-48	175.0	COG0222@1|root,COG0222@2|Bacteria,3Y50J@57723|Acidobacteria	57723|Acidobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
LZS3_k127_4669970_37	234267.Acid_5459	4.794e-55	198.0	COG0244@1|root,COG0244@2|Bacteria,3Y4N2@57723|Acidobacteria	57723|Acidobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
LZS3_k127_4669970_18	1267535.KB906767_gene4466	5.29e-101	333.0	COG0081@1|root,COG0081@2|Bacteria,3Y2HX@57723|Acidobacteria,2JITV@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
LZS3_k127_4669970_35	1382359.JIAL01000001_gene1826	8.194e-60	214.0	COG0080@1|root,COG0080@2|Bacteria,3Y4PQ@57723|Acidobacteria,2JJ82@204432|Acidobacteriia	204432|Acidobacteriia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
LZS3_k127_4669970_23	234267.Acid_6325	7.401e-86	289.0	COG0250@1|root,COG0250@2|Bacteria,3Y3ZR@57723|Acidobacteria	57723|Acidobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
LZS3_k127_4669970_59	1340493.JNIF01000003_gene3826	2.987e-09	63.0	COG0690@1|root,COG0690@2|Bacteria,3Y5R4@57723|Acidobacteria	57723|Acidobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
LZS3_k127_4669970_56	189425.PGRAT_11670	1.558e-14	74.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,4HNIM@91061|Bacilli,26ZXX@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
LZS3_k127_4669970_55	289376.THEYE_A1448	2.342e-15	75.0	COG0050@1|root,COG0050@2|Bacteria,3J0DG@40117|Nitrospirae	40117|Nitrospirae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS3_k127_4674427_5	1121423.JONT01000003_gene1087	3.53e-35	135.0	COG2221@1|root,COG2221@2|Bacteria,1TRP0@1239|Firmicutes,24A5T@186801|Clostridia,260BJ@186807|Peptococcaceae	186801|Clostridia	C	PFAM nitrite and sulphite reductase 4Fe-4S	dsrA	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
LZS3_k127_4674427_12	661367.LLO_2905	2.054e-17	85.0	COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,1RMAQ@1236|Gammaproteobacteria,1JF9E@118969|Legionellales	118969|Legionellales	L	Transposase IS116/IS110/IS902 family	-	GO:0003674,GO:0003824,GO:0004803,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0032196,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140097,GO:1901360	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
LZS3_k127_4674427_10	1121396.KB893120_gene3067	1.124e-20	94.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4674427_6	156889.Mmc1_2864	1.655e-29	125.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_4674427_7	1173022.Cri9333_3853	1.626e-26	110.0	2E5P1@1|root,330DP@2|Bacteria,1G84E@1117|Cyanobacteria,1HCXI@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
LZS3_k127_4674427_9	497965.Cyan7822_4394	4.683e-21	93.0	2E3EN@1|root,32YDN@2|Bacteria,1G85N@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
LZS3_k127_4674427_11	1303518.CCALI_00449	9.855e-20	91.0	COG1743@1|root,COG1743@2|Bacteria	2|Bacteria	L	DNA methylAse	-	-	-	-	-	-	-	-	-	-	-	-	DUF1156
LZS3_k127_4674427_8	1340493.JNIF01000003_gene1500	2.37e-25	113.0	COG1595@1|root,COG1595@2|Bacteria,3Y8Q7@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_4674427_0	1340493.JNIF01000003_gene1501	7.65e-129	441.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR,VIT,VWA_3
LZS3_k127_4674427_2	1340493.JNIF01000003_gene1502	1.887e-111	369.0	COG1131@1|root,COG1131@2|Bacteria,3Y6U6@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_4674427_4	1340493.JNIF01000003_gene1503	7.353e-66	234.0	COG1277@1|root,COG1277@2|Bacteria,3Y839@57723|Acidobacteria	57723|Acidobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
LZS3_k127_4674427_1	1340493.JNIF01000003_gene1504	4.726e-113	374.0	COG1131@1|root,COG1131@2|Bacteria,3Y4YH@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_4674427_3	1340493.JNIF01000003_gene1505	5.219e-74	262.0	2F2X8@1|root,33VSU@2|Bacteria,3Y7XB@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4674427_13	1189612.A33Q_2788	2.823e-06	52.0	28P7W@1|root,2ZC23@2|Bacteria,4NNAG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4674427_14	768671.ThimaDRAFT_4529	0.0009424	46.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
LZS3_k127_4741900_0	485915.Dret_0373	2.825e-76	268.0	COG3464@1|root,COG3464@2|Bacteria,1R4DH@1224|Proteobacteria,43AQ4@68525|delta/epsilon subdivisions,2X63W@28221|Deltaproteobacteria,2MGXP@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM transposase IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
LZS3_k127_4741900_7	452637.Oter_0063	1.173e-10	66.0	COG2823@1|root,COG2823@2|Bacteria,46XV8@74201|Verrucomicrobia,3K8D0@414999|Opitutae	414999|Opitutae	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS3_k127_4741900_5	1205680.CAKO01000002_gene2477	1.626e-18	85.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2UGKQ@28211|Alphaproteobacteria,2JUN0@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
LZS3_k127_4741900_2	414684.RC1_3454	3.78e-27	123.0	COG0517@1|root,COG0517@2|Bacteria,1NMH1@1224|Proteobacteria,2U9D8@28211|Alphaproteobacteria,2JT6V@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_4741900_1	234267.Acid_4407	3.988e-72	256.0	COG3861@1|root,COG3861@2|Bacteria,3Y5WZ@57723|Acidobacteria	57723|Acidobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS3_k127_4741900_6	1267533.KB906733_gene3079	3.028e-15	86.0	COG2823@1|root,COG2823@2|Bacteria,3Y8FT@57723|Acidobacteria,2JNE8@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS3_k127_4741900_3	156889.Mmc1_2864	2.014e-20	98.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_4742308_22	204669.Acid345_3426	1.983e-05	49.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria,2JIG8@204432|Acidobacteriia	204432|Acidobacteriia	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
LZS3_k127_4742308_16	1089550.ATTH01000001_gene1178	3.817e-47	179.0	COG0454@1|root,COG0456@2|Bacteria,4NT3M@976|Bacteroidetes,1FK4C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_4742308_6	1267535.KB906767_gene1544	6.729e-169	539.0	COG0436@1|root,COG0436@2|Bacteria,3Y3DG@57723|Acidobacteria,2JMAM@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS3_k127_4742308_8	1267535.KB906767_gene1521	2.345e-146	505.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,TonB_dep_Rec
LZS3_k127_4742308_14	1200567.JNKD01000002_gene2226	8.024e-93	335.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1Y47Q@135624|Aeromonadales	135624|Aeromonadales	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
LZS3_k127_4742308_12	1267535.KB906767_gene757	4.385e-125	410.0	COG0772@1|root,COG0772@2|Bacteria,3Y3DZ@57723|Acidobacteria,2JINX@204432|Acidobacteriia	204432|Acidobacteriia	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
LZS3_k127_4742308_1	1340493.JNIF01000003_gene3682	7.848e-202	646.0	COG0768@1|root,COG0768@2|Bacteria,3Y3MX@57723|Acidobacteria	57723|Acidobacteria	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
LZS3_k127_4742308_19	1267533.KB906733_gene3088	1.618e-24	113.0	2CM1I@1|root,32SDF@2|Bacteria,3Y571@57723|Acidobacteria,2JJRW@204432|Acidobacteriia	204432|Acidobacteriia	S	shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
LZS3_k127_4742308_15	234267.Acid_3812	6.623e-67	246.0	COG1792@1|root,COG1792@2|Bacteria,3Y3CK@57723|Acidobacteria	57723|Acidobacteria	M	Rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
LZS3_k127_4742308_3	234267.Acid_3811	8.996e-189	593.0	COG1077@1|root,COG1077@2|Bacteria,3Y3VC@57723|Acidobacteria	57723|Acidobacteria	D	TIGRFAM Cell shape determining protein MreB Mrl	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
LZS3_k127_4742308_17	234267.Acid_5628	1.06e-45	175.0	COG1214@1|root,COG1214@2|Bacteria,3Y5ED@57723|Acidobacteria	57723|Acidobacteria	O	PFAM Peptidase M22, glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
LZS3_k127_4742308_7	234267.Acid_5629	7.24e-156	515.0	COG5512@1|root,COG5512@2|Bacteria,3Y7CI@57723|Acidobacteria	57723|Acidobacteria	S	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
LZS3_k127_4742308_5	234267.Acid_0384	3.113e-169	549.0	COG0608@1|root,COG0608@2|Bacteria,3Y3HI@57723|Acidobacteria	57723|Acidobacteria	L	single-stranded-DNA-specific exonuclease RecJ	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
LZS3_k127_4742308_2	234267.Acid_0382	6.645e-190	611.0	COG1012@1|root,COG1012@2|Bacteria,3Y3MS@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.1.1.1,1.2.1.10,1.2.1.81	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
LZS3_k127_4742308_18	1191523.MROS_1898	1.044e-34	135.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
LZS3_k127_4742308_4	344747.PM8797T_08574	2.184e-181	598.0	COG4225@1|root,COG4225@2|Bacteria,2IZFK@203682|Planctomycetes	203682|Planctomycetes	S	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
LZS3_k127_4742308_9	1340493.JNIF01000004_gene375	6.202e-143	477.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
LZS3_k127_4742308_13	234267.Acid_3254	5.099e-120	396.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_4742308_0	1382359.JIAL01000001_gene788	2.113e-218	688.0	COG1884@1|root,COG1884@2|Bacteria,3Y2QA@57723|Acidobacteria,2JKR7@204432|Acidobacteriia	204432|Acidobacteriia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS3_k127_4742308_11	1219084.AP014508_gene789	2.772e-127	432.0	COG4666@1|root,COG4666@2|Bacteria	2|Bacteria	P	Tripartite ATP-independent periplasmic transporter, DctM component	siaT_1	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
LZS3_k127_4742308_10	1267535.KB906767_gene1102	9.454e-131	435.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS3_k127_4742308_21	1267535.KB906767_gene1103	3.266e-11	66.0	COG0745@1|root,COG0745@2|Bacteria	1267535.KB906767_gene1103|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4757067_15	1340493.JNIF01000003_gene1818	1.425e-30	130.0	COG0457@1|root,COG0457@2|Bacteria	1340493.JNIF01000003_gene1818|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4757067_0	1340493.JNIF01000003_gene1819	0.0	1433.0	COG2911@1|root,COG4775@1|root,COG2911@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277,ko:K09800	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	AsmA_2,Bac_surface_Ag,DUF748,POTRA,TamB
LZS3_k127_4757067_11	1173028.ANKO01000170_gene3346	5.698e-89	302.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Ribonuclease BN-like family	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS3_k127_4757067_8	1210884.HG799462_gene8794	6.915e-98	354.0	COG4191@1|root,COG4191@2|Bacteria,2J2PC@203682|Planctomycetes	203682|Planctomycetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
LZS3_k127_4757067_2	143224.JQMD01000002_gene209	1.782e-195	634.0	COG3540@1|root,COG3540@2|Bacteria	2|Bacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
LZS3_k127_4757067_18	1340493.JNIF01000003_gene2900	9.736e-14	85.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	ko:K07004,ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	ASH,CHU_C,DUF11,SGL
LZS3_k127_4757067_7	1173028.ANKO01000244_gene3949	9.691e-111	363.0	COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1HHDU@1150|Oscillatoriales	1117|Cyanobacteria	S	Phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
LZS3_k127_4757067_10	552811.Dehly_1170	9.228e-90	314.0	COG0501@1|root,COG0501@2|Bacteria,2G6UV@200795|Chloroflexi,34D0W@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
LZS3_k127_4757067_13	945713.IALB_2434	1.232e-70	243.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
LZS3_k127_4757067_17	945713.IALB_2435	1.657e-15	84.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
LZS3_k127_4757067_1	690850.Desaf_3621	2.398e-300	954.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M7S1@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_4757067_12	1340493.JNIF01000003_gene2863	7.591e-86	299.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K06889	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Asp_protease_2,Chlorophyllase2,DLH
LZS3_k127_4757067_6	234267.Acid_6980	4.833e-121	394.0	COG0329@1|root,COG0329@2|Bacteria,3Y3V8@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS3_k127_4757067_9	234267.Acid_6981	7.813e-97	323.0	COG0289@1|root,COG0289@2|Bacteria,3Y50R@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DapB family	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
LZS3_k127_4757067_3	234267.Acid_6982	3.386e-169	542.0	COG0527@1|root,COG0527@2|Bacteria,3Y34W@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
LZS3_k127_4757067_4	234267.Acid_6983	6.968e-155	496.0	COG0136@1|root,COG0136@2|Bacteria,3Y346@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS3_k127_4757067_5	234267.Acid_6984	2.945e-121	398.0	COG0624@1|root,COG0624@2|Bacteria,3Y2K0@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_4757067_14	756272.Plabr_2698	6.995e-58	219.0	COG2960@1|root,COG2960@2|Bacteria,2IX87@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
LZS3_k127_4757067_16	1254432.SCE1572_17845	1.778e-26	115.0	COG5297@1|root,COG5297@2|Bacteria,1MV16@1224|Proteobacteria,430JB@68525|delta/epsilon subdivisions,2WVTU@28221|Deltaproteobacteria,2YWQ0@29|Myxococcales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF1592)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
LZS3_k127_4779024_0	177437.HRM2_15540	1.229e-266	839.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2MIHW@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
LZS3_k127_4779024_6	1123508.JH636439_gene1117	8.069e-59	216.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS3_k127_4779024_3	234267.Acid_1508	3.731e-90	308.0	COG2421@1|root,COG2421@2|Bacteria	2|Bacteria	C	formamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
LZS3_k127_4779024_8	1200792.AKYF01000021_gene5396	1.456e-35	152.0	COG4927@1|root,COG4927@2|Bacteria,1UEAE@1239|Firmicutes,4HCWI@91061|Bacilli	91061|Bacilli	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	ko:K19200	ko00311,ko01100,ko01130,map00311,map01100,map01130	-	-	-	ko00000,ko00001,ko01002	-	-	-	AAT
LZS3_k127_4779024_9	1433126.BN938_1424	8.967e-26	119.0	COG2520@1|root,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	XK27_03530	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,rRNA_methylase
LZS3_k127_4779024_7	1158760.AQXP01000033_gene974	5.233e-55	216.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales	135613|Chromatiales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_4779024_4	290318.Cvib_0174	1.337e-85	293.0	COG3264@1|root,COG3264@2|Bacteria,1FD9A@1090|Chlorobi	1090|Chlorobi	M	PFAM MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS3_k127_4779024_5	234267.Acid_7823	9.932e-70	251.0	COG2017@1|root,COG2017@2|Bacteria,3Y4YM@57723|Acidobacteria	57723|Acidobacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4779024_2	1340493.JNIF01000003_gene2935	8.555e-100	332.0	COG0179@1|root,COG0179@2|Bacteria,3Y6BP@57723|Acidobacteria	57723|Acidobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
LZS3_k127_4779024_1	234267.Acid_0968	9.337e-217	679.0	COG1012@1|root,COG1012@2|Bacteria,3Y3V5@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.28	ko:K00141,ko:K22187	ko00040,ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00040,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667,R11768	RC00075,RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_4822093_5	404589.Anae109_2667	8.005e-107	354.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
LZS3_k127_4822093_9	204669.Acid345_0722	1.219e-86	304.0	COG0577@1|root,COG0577@2|Bacteria,3Y3XI@57723|Acidobacteria,2JI94@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_4822093_6	1267533.KB906740_gene380	4.167e-99	337.0	COG0577@1|root,COG0577@2|Bacteria,3Y2MV@57723|Acidobacteria,2JI8C@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_4822093_3	1340493.JNIF01000003_gene3900	1.464e-120	405.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_4822093_13	204669.Acid345_0118	1.767e-53	194.0	2CK1C@1|root,32SJA@2|Bacteria,3Y543@57723|Acidobacteria,2JJTF@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4822093_11	429009.Adeg_1589	3.1e-56	206.0	COG1801@1|root,COG1801@2|Bacteria,1TPX4@1239|Firmicutes,24IAX@186801|Clostridia,42GB4@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS3_k127_4822093_0	671143.DAMO_2917	8.945e-211	676.0	COG0667@1|root,COG1331@1|root,COG0667@2|Bacteria,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,GlcNAc_2-epim,Thioredox_DsbH
LZS3_k127_4822093_4	234267.Acid_7881	1.734e-118	389.0	COG0812@1|root,COG0812@2|Bacteria,3Y3AT@57723|Acidobacteria	57723|Acidobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
LZS3_k127_4822093_10	234267.Acid_7882	1.195e-66	235.0	COG5587@1|root,COG5587@2|Bacteria,3Y4D4@57723|Acidobacteria	57723|Acidobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
LZS3_k127_4822093_15	643648.Slip_1876	3.008e-37	147.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,42K2U@68298|Syntrophomonadaceae	186801|Clostridia	N	OmpA family	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
LZS3_k127_4822093_2	1227739.Hsw_4060	4.618e-136	443.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	MFS_MOT1
LZS3_k127_4822093_12	1499967.BAYZ01000007_gene5399	1.029e-55	205.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
LZS3_k127_4822093_7	234267.Acid_2075	5.357e-91	324.0	COG3356@1|root,COG3356@2|Bacteria,3Y5I7@57723|Acidobacteria	57723|Acidobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
LZS3_k127_4822093_8	1123508.JH636439_gene1117	2.659e-88	303.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS3_k127_4822093_14	745411.B3C1_02980	7.458e-50	188.0	COG0431@1|root,COG0431@2|Bacteria	745411.B3C1_02980|-	S	FMN reductase (NADPH) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4822093_1	234267.Acid_3333	5.195e-138	451.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	OmpA,PD40,PI-PLC-X,Pectate_lyase22,TIR_2
LZS3_k127_4822093_16	234267.Acid_1189	1.143e-08	61.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_4828129_5	886293.Sinac_0923	2.16e-86	307.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPU@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS3_k127_4828129_2	234267.Acid_5310	9.163e-172	546.0	COG1960@1|root,COG1960@2|Bacteria,3Y32R@57723|Acidobacteria	57723|Acidobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_4828129_7	234267.Acid_0817	4.282e-53	196.0	COG1579@1|root,COG1579@2|Bacteria,3Y509@57723|Acidobacteria	57723|Acidobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
LZS3_k127_4828129_10	1382359.JIAL01000001_gene1971	8.32e-22	98.0	COG1923@1|root,COG1923@2|Bacteria,3Y59T@57723|Acidobacteria,2JJSQ@204432|Acidobacteriia	204432|Acidobacteriia	S	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
LZS3_k127_4828129_3	1267535.KB906767_gene4617	1.495e-130	432.0	COG2262@1|root,COG2262@2|Bacteria,3Y2FK@57723|Acidobacteria,2JI0F@204432|Acidobacteriia	204432|Acidobacteriia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS3_k127_4828129_8	204669.Acid345_4037	1.837e-34	142.0	COG0741@1|root,COG0741@2|Bacteria,3Y4SM@57723|Acidobacteria,2JJJQ@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
LZS3_k127_4828129_1	1340493.JNIF01000003_gene1702	2.872e-178	566.0	COG0498@1|root,COG0498@2|Bacteria,3Y2GX@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM Threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_4828129_6	1123242.JH636435_gene2640	1.07e-56	208.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	MA20_16785	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4828129_0	103690.17135536	9.019e-247	797.0	COG0642@1|root,COG0784@1|root,COG1196@1|root,COG1352@1|root,COG2201@1|root,COG0784@2|Bacteria,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HIYG@1161|Nostocales	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
LZS3_k127_4828129_4	243231.GSU2816	2.423e-97	338.0	COG2204@1|root,COG4191@1|root,COG5000@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,43TMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
LZS3_k127_4852446_27	1267534.KB906754_gene2730	0.0004302	48.0	COG0154@1|root,COG0154@2|Bacteria,3Y41H@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
LZS3_k127_4852446_10	391625.PPSIR1_15265	1.12e-112	371.0	COG0258@1|root,COG0258@2|Bacteria,1QV40@1224|Proteobacteria,43BZM@68525|delta/epsilon subdivisions,2X7AE@28221|Deltaproteobacteria,2YUE3@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
LZS3_k127_4852446_18	1267535.KB906767_gene2266	1.888e-46	179.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS3_k127_4852446_19	204669.Acid345_4082	2.515e-44	175.0	28QZS@1|root,2ZDEJ@2|Bacteria,3Y4BV@57723|Acidobacteria,2JKG1@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4852446_20	330214.NIDE3217	5.068e-40	159.0	COG1678@1|root,COG1678@2|Bacteria	2|Bacteria	K	ribonucleoside-diphosphate reductase activity	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
LZS3_k127_4852446_15	1267535.KB906767_gene3727	6.064e-72	249.0	COG2930@1|root,COG2930@2|Bacteria,3Y6Q0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
LZS3_k127_4852446_24	756272.Plabr_2212	2.768e-18	91.0	COG4886@1|root,COG4886@2|Bacteria,2J0RN@203682|Planctomycetes	203682|Planctomycetes	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
LZS3_k127_4852446_7	1047013.AQSP01000076_gene1470	1.853e-141	462.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_4852446_26	1380600.AUYN01000006_gene519	1.918e-13	73.0	COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,1HZEG@117743|Flavobacteriia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PSCyt1
LZS3_k127_4852446_22	1189612.A33Q_3360	3.444e-32	139.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,PKD,SprB
LZS3_k127_4852446_5	1403819.BATR01000181_gene6201	2.394e-183	584.0	COG0477@1|root,COG0477@2|Bacteria,46TSP@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_4852446_21	1267535.KB906767_gene2728	1.075e-38	146.0	COG0234@1|root,COG0234@2|Bacteria,3Y4VQ@57723|Acidobacteria	57723|Acidobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS3_k127_4852446_0	234267.Acid_6747	1.856e-261	814.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria	57723|Acidobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS3_k127_4852446_8	497964.CfE428DRAFT_6614	7.937e-132	436.0	2BZ9C@1|root,2Z998@2|Bacteria,46S4U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS3_k127_4852446_13	234267.Acid_1383	6.482e-84	285.0	COG1028@1|root,COG1028@2|Bacteria,3Y4WX@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.175	ko:K00059,ko:K22185	ko00040,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00040,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R01429,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00066,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_4852446_11	65093.PCC7418_1345	1.574e-90	310.0	COG0276@1|root,COG0276@2|Bacteria,1G1UI@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Chloroa_b-bind,Ferrochelatase
LZS3_k127_4852446_6	234267.Acid_2435	1.57e-174	559.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_4852446_2	234267.Acid_5088	4.498e-205	649.0	COG1012@1|root,COG1012@2|Bacteria,3Y3CY@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_4852446_17	234267.Acid_7300	6.823e-60	211.0	COG0432@1|root,COG0432@2|Bacteria,3Y4YD@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS3_k127_4852446_23	357808.RoseRS_1412	4.527e-32	136.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi,377N7@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
LZS3_k127_4852446_1	1267535.KB906767_gene3777	4.54e-242	756.0	COG4102@1|root,COG4102@2|Bacteria,3Y6RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_4852446_9	204669.Acid345_4646	1.168e-126	417.0	COG0303@1|root,COG0303@2|Bacteria,3Y3F0@57723|Acidobacteria,2JICE@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS3_k127_4852446_16	234267.Acid_1404	6.58e-62	216.0	COG0315@1|root,COG0315@2|Bacteria,3Y4IY@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
LZS3_k127_4852446_14	234267.Acid_1402	2.102e-72	258.0	COG2304@1|root,COG2304@2|Bacteria,3Y99W@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
LZS3_k127_4852446_3	671143.DAMO_1547	2.245e-191	625.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	pgcA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS3_k127_4852446_25	756272.Plabr_2308	5.488e-17	84.0	2EJH6@1|root,33D83@2|Bacteria,2J1HK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
LZS3_k127_4852446_4	314230.DSM3645_18936	4.208e-187	598.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS3_k127_4852446_12	1123508.JH636441_gene3736	9.408e-87	298.0	COG0438@1|root,COG0438@2|Bacteria,2IXZX@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_4925360_32	404589.Anae109_0475	4.099e-67	241.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
LZS3_k127_4925360_43	671143.DAMO_0603	8.716e-15	76.0	2C2YU@1|root,33M8J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4925360_23	278963.ATWD01000002_gene751	1.139e-81	290.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
LZS3_k127_4925360_7	1379698.RBG1_1C00001G0607	5.571e-178	585.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS3_k127_4925360_5	1340493.JNIF01000003_gene2866	1.286e-197	622.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_4925360_2	234267.Acid_4486	5.306e-235	740.0	COG0595@1|root,COG0595@2|Bacteria,3Y2NH@57723|Acidobacteria	57723|Acidobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
LZS3_k127_4925360_39	1232437.KL662011_gene1449	2.45e-43	170.0	COG0484@1|root,COG0484@2|Bacteria,1RHHJ@1224|Proteobacteria,42SMN@68525|delta/epsilon subdivisions,2WPJN@28221|Deltaproteobacteria,2MNCE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
LZS3_k127_4925360_12	66692.ABC3604	4.224e-140	464.0	COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,4HADN@91061|Bacilli,1ZBVK@1386|Bacillus	91061|Bacilli	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
LZS3_k127_4925360_21	234267.Acid_0773	3.027e-86	290.0	COG1011@1|root,COG1011@2|Bacteria,3Y4BM@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS3_k127_4925360_40	234267.Acid_0774	5.519e-34	151.0	COG0810@1|root,COG0810@2|Bacteria,3Y8PD@57723|Acidobacteria	57723|Acidobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
LZS3_k127_4925360_29	234267.Acid_3418	1.088e-73	254.0	COG1403@1|root,COG1403@2|Bacteria,3Y3PW@57723|Acidobacteria	57723|Acidobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
LZS3_k127_4925360_37	243231.GSU0124	2.004e-48	183.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,43UT3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
LZS3_k127_4925360_42	1047013.AQSP01000139_gene2379	1.391e-22	101.0	COG1734@1|root,COG1734@2|Bacteria,2NQ6S@2323|unclassified Bacteria	2|Bacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS3_k127_4925360_11	335543.Sfum_2312	2.638e-153	493.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,42RTY@68525|delta/epsilon subdivisions,2WNFS@28221|Deltaproteobacteria,2MRVF@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1,3.5.5.7	ko:K01501,ko:K01502	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05358,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC01336,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
LZS3_k127_4925360_45	234267.Acid_2817	1.304e-06	58.0	290IJ@1|root,2ZN7C@2|Bacteria,3Y95B@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4925360_34	234267.Acid_7275	5.698e-60	211.0	COG0669@1|root,COG0669@2|Bacteria,3Y4B6@57723|Acidobacteria	57723|Acidobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS3_k127_4925360_8	234267.Acid_7274	7.114e-166	530.0	COG0436@1|root,COG0436@2|Bacteria,3Y2IZ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM aminotransferase, class I	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_4925360_31	1304880.JAGB01000002_gene1921	8.177e-69	248.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,2487K@186801|Clostridia	186801|Clostridia	G	mannose-6-phosphate isomerase, class I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS19425	PMI_typeI
LZS3_k127_4925360_38	1267535.KB906767_gene4740	1.348e-47	183.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria,2JI38@204432|Acidobacteriia	204432|Acidobacteriia	M	TIGRFAM TonB	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS3_k127_4925360_14	1340493.JNIF01000004_gene17	5.62e-137	452.0	COG1680@1|root,COG1680@2|Bacteria,3Y8A8@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_4925360_25	3694.POPTR_0003s06720.1	1.991e-80	282.0	COG1304@1|root,KOG0538@2759|Eukaryota,37Q8R@33090|Viridiplantae,3GEWX@35493|Streptophyta,4JNSE@91835|fabids	35493|Streptophyta	C	(S)-2-hydroxy-acid oxidase	-	GO:0003674,GO:0003824,GO:0003973,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0008150,GO:0008152,GO:0008891,GO:0009853,GO:0009987,GO:0010109,GO:0016032,GO:0016491,GO:0016614,GO:0016899,GO:0019048,GO:0019222,GO:0031323,GO:0035821,GO:0042579,GO:0043094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044003,GO:0044237,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051817,GO:0055114,GO:0065007	1.1.3.15	ko:K11517	ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00630,map01100,map01110,map01120,map01130,map01200,map04146	M00532	R00475	RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
LZS3_k127_4925360_20	1267534.KB906756_gene415	2.377e-87	295.0	COG1738@1|root,COG1738@2|Bacteria,3Y35H@57723|Acidobacteria,2JIRA@204432|Acidobacteriia	204432|Acidobacteriia	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
LZS3_k127_4925360_3	1267535.KB906767_gene3954	1.441e-225	711.0	COG4799@1|root,COG4799@2|Bacteria,3Y3DC@57723|Acidobacteria,2JIP2@204432|Acidobacteriia	204432|Acidobacteriia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
LZS3_k127_4925360_35	216142.LT40_01795	1.522e-53	198.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,1RNY2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_4925360_24	234267.Acid_0222	1.603e-81	300.0	COG0515@1|root,COG0515@2|Bacteria,3Y6PF@57723|Acidobacteria	57723|Acidobacteria	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_4925360_6	344747.PM8797T_09724	2.13e-188	600.0	COG2355@1|root,COG2355@2|Bacteria,2IXP4@203682|Planctomycetes	203682|Planctomycetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
LZS3_k127_4925360_17	1267535.KB906767_gene659	3.035e-108	358.0	COG1273@1|root,COG1273@2|Bacteria,3Y4E7@57723|Acidobacteria,2JNYV@204432|Acidobacteriia	204432|Acidobacteriia	L	Ku70/Ku80 beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Ku
LZS3_k127_4925360_15	344747.PM8797T_30581	1.069e-125	420.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4433,MR_MLE_C
LZS3_k127_4925360_28	177437.HRM2_23690	2.545e-76	271.0	COG0575@1|root,COG1408@1|root,COG0575@2|Bacteria,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WIMQ@28221|Deltaproteobacteria,2MHZJ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	CDP-archaeol synthase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	CarS-like,Metallophos
LZS3_k127_4925360_4	1303518.CCALI_02688	2.41e-201	639.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
LZS3_k127_4925360_0	234267.Acid_3816	0.0	2065.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,3Y2JQ@57723|Acidobacteria	57723|Acidobacteria	E	glutamate synthase alpha subunit	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
LZS3_k127_4925360_19	1123242.JH636434_gene5302	5.934e-97	334.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene5302|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4925360_18	1267535.KB906767_gene1277	5.89e-106	352.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria,2JIRB@204432|Acidobacteriia	204432|Acidobacteriia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
LZS3_k127_4925360_36	234267.Acid_4383	4.133e-49	186.0	COG1612@1|root,COG1612@2|Bacteria	2|Bacteria	O	heme a metabolic process	ctaA	-	-	ko:K02259,ko:K03110	ko00190,ko00860,ko01100,ko01110,ko02020,ko02024,ko03060,ko03070,ko04714,map00190,map00860,map01100,map01110,map02020,map02024,map03060,map03070,map04714	M00154,M00335	R07412	RC00769	ko00000,ko00001,ko00002,ko02044,ko03029	3.A.5.1,3.A.5.2,3.A.5.7,3.D.4.4	-	-	COX15-CtaA
LZS3_k127_4925360_26	234267.Acid_4384	3.447e-80	276.0	COG3794@1|root,COG3794@2|Bacteria,3Y4A0@57723|Acidobacteria	57723|Acidobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_4925360_1	234267.Acid_4385	0.0	1103.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
LZS3_k127_4925360_9	234267.Acid_4386	4.313e-156	496.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
LZS3_k127_4925360_10	234267.Acid_4387	2.563e-153	488.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
LZS3_k127_4925360_30	234267.Acid_4388	4.568e-72	248.0	COG0723@1|root,COG0723@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on diphenols and related substances as donors	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
LZS3_k127_4925360_27	1499967.BAYZ01000089_gene5015	2.661e-77	281.0	COG1212@1|root,COG1212@2|Bacteria,2NP8R@2323|unclassified Bacteria	2|Bacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
LZS3_k127_4925360_22	234267.Acid_1845	7.229e-85	290.0	COG1694@1|root,COG3956@2|Bacteria,3Y46M@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM MazG family protein	-	-	3.6.1.66,3.6.1.9	ko:K02428,ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R01855,R02100,R02720,R03004,R03036,R03531,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
LZS3_k127_4925360_33	1267535.KB906767_gene874	2.178e-66	239.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4925360_13	204669.Acid345_2187	5.257e-139	456.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria,2JITG@204432|Acidobacteriia	204432|Acidobacteriia	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_4925360_41	234267.Acid_6884	1.031e-23	117.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
LZS3_k127_4925360_16	234267.Acid_6881	2.318e-117	420.0	COG1361@1|root,COG3534@1|root,COG4625@1|root,COG1361@2|Bacteria,COG3534@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	2|Bacteria	M	PKD domain containing protein	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,DUF4347,Glyco_hydro_43,He_PIG,P_proprotein,Peptidase_S8,TIG
LZS3_k127_4941444_8	234267.Acid_7441	2.875e-26	117.0	COG1216@1|root,COG1216@2|Bacteria,3Y7JI@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
LZS3_k127_4941444_6	1267535.KB906767_gene3849	1.484e-53	201.0	COG1216@1|root,COG1216@2|Bacteria,3Y80R@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_4941444_5	234267.Acid_5385	4.249e-67	243.0	COG1063@1|root,COG1063@2|Bacteria,3Y6GC@57723|Acidobacteria	57723|Acidobacteria	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_4941444_0	216591.BCAL0206	2.179e-301	962.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,1K37E@119060|Burkholderiaceae	28216|Betaproteobacteria	C	oxidoreductase	porG	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
LZS3_k127_4941444_2	1382306.JNIM01000001_gene1966	5.497e-153	500.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
LZS3_k127_4941444_3	1329516.JPST01000013_gene263	6.814e-152	491.0	COG3007@1|root,COG3007@2|Bacteria,1TWIF@1239|Firmicutes,4HCSV@91061|Bacilli,27BD1@186824|Thermoactinomycetaceae	91061|Bacilli	I	NAD(P)H binding domain of trans-2-enoyl-CoA reductase	fabV	-	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
LZS3_k127_4941444_4	234267.Acid_7340	1.747e-76	259.0	COG5405@1|root,COG5405@2|Bacteria,3Y42U@57723|Acidobacteria	57723|Acidobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
LZS3_k127_4941444_1	234267.Acid_7339	5.712e-227	709.0	COG1220@1|root,COG1220@2|Bacteria,3Y2K2@57723|Acidobacteria	57723|Acidobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
LZS3_k127_4941444_7	1340493.JNIF01000003_gene1488	1.045e-41	168.0	COG4733@1|root,COG4733@2|Bacteria,3Y53H@57723|Acidobacteria	57723|Acidobacteria	S	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4946331_8	1121939.L861_02680	4.331e-90	309.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.3.6,6.3.5.4	ko:K01953,ko:K18316	ko00250,ko00332,ko01100,ko01110,ko01130,ko02024,map00250,map00332,map01100,map01110,map01130,map02024	M00675	R00578,R10556	RC00010,RC03195	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Asn_synthase,DUF1933,GATase_7
LZS3_k127_4946331_4	1123508.JH636445_gene6791	2.018e-132	440.0	COG0405@1|root,COG0405@2|Bacteria,2IWWP@203682|Planctomycetes	2|Bacteria	E	gamma-glutamyltransferase	MA20_09815	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_4946331_9	1380394.JADL01000013_gene577	2.077e-70	249.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JSGW@204441|Rhodospirillales	204441|Rhodospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	ko:K22303	-	-	-	-	ko00000,ko01000	-	-	-	TauD
LZS3_k127_4946331_0	1340493.JNIF01000003_gene4575	9.914e-207	673.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PSCyt1,PSCyt2,PSD1
LZS3_k127_4946331_3	1340493.JNIF01000003_gene4574	1.138e-166	538.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_4946331_6	234267.Acid_6335	2.946e-125	414.0	COG2706@1|root,COG2706@2|Bacteria,3Y4KD@57723|Acidobacteria	57723|Acidobacteria	G	PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
LZS3_k127_4946331_13	531844.FIC_00803	1.232e-25	113.0	COG0662@1|root,COG0662@2|Bacteria,4PNAM@976|Bacteroidetes	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_4946331_10	452637.Oter_1109	1.782e-53	192.0	COG4276@1|root,COG4276@2|Bacteria,46X6Q@74201|Verrucomicrobia,3K9Y1@414999|Opitutae	414999|Opitutae	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4946331_2	1123242.JH636435_gene793	2.284e-179	574.0	COG0415@1|root,COG0415@2|Bacteria,2IZKY@203682|Planctomycetes	203682|Planctomycetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
LZS3_k127_4946331_1	903818.KI912268_gene1318	6.034e-197	630.0	COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
LZS3_k127_4946331_11	756272.Plabr_3042	3.652e-51	185.0	COG3476@1|root,COG3476@2|Bacteria,2J03F@203682|Planctomycetes	203682|Planctomycetes	T	PFAM TspO MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
LZS3_k127_4946331_5	1267535.KB906767_gene5103	2.231e-125	409.0	COG0667@1|root,COG0667@2|Bacteria,3Y2TN@57723|Acidobacteria,2JMH3@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_4946331_14	1340493.JNIF01000003_gene3111	1.197e-23	113.0	2EJ55@1|root,33CWC@2|Bacteria	2|Bacteria	S	Intracellular proteinase inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI
LZS3_k127_4946331_7	234267.Acid_1898	2.505e-117	392.0	28JXC@1|root,2Z8EX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4946331_12	648885.KB316282_gene1480	4.319e-36	138.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria,1JUR8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	MA20_22790	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
LZS3_k127_4953527_17	344747.PM8797T_27694	8.46e-29	117.0	2FJV6@1|root,34BHQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4953527_22	1283300.ATXB01000001_gene1694	2.085e-20	98.0	COG0055@1|root,COG0055@2|Bacteria,1N6UZ@1224|Proteobacteria,1RNQW@1236|Gammaproteobacteria,1XFZ1@135618|Methylococcales	135618|Methylococcales	C	ATP synthase alpha/beta chain, C terminal domain	-	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS3_k127_4953527_7	1210884.HG799464_gene11097	1.822e-96	349.0	COG2010@1|root,COG2010@2|Bacteria,2IXIX@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
LZS3_k127_4953527_0	502025.Hoch_0335	1.031e-169	544.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2YVFZ@29|Myxococcales	28221|Deltaproteobacteria	S	Major facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
LZS3_k127_4953527_24	1089453.GOSPT_129_00150	6.789e-12	70.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4GANG@85026|Gordoniaceae	201174|Actinobacteria	T	ANTAR	pdtaR	GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
LZS3_k127_4953527_20	382464.ABSI01000013_gene1931	6.466e-23	108.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_4953527_29	1267535.KB906767_gene1333	0.0002592	49.0	COG0745@1|root,COG0745@2|Bacteria,3Y8Y3@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_4953527_18	648757.Rvan_1510	2.771e-24	109.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2U0JP@28211|Alphaproteobacteria,3N71U@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_4953527_19	1201293.AKXQ01000009_gene898	5.419e-24	107.0	COG2010@1|root,COG2010@2|Bacteria,1N5P8@1224|Proteobacteria,1S9K3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS3_k127_4953527_4	502025.Hoch_5800	7.451e-115	386.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2YU1M@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
LZS3_k127_4953527_5	595460.RRSWK_05252	5.508e-111	372.0	COG3174@1|root,COG3174@2|Bacteria,2J41N@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
LZS3_k127_4953527_11	331678.Cphamn1_2116	3.316e-60	211.0	COG2606@1|root,COG2606@2|Bacteria,1FF46@1090|Chlorobi	1090|Chlorobi	S	PFAM YbaK prolyl-tRNA synthetase associated region	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
LZS3_k127_4953527_9	706587.Desti_2130	1.211e-66	239.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,43AV8@68525|delta/epsilon subdivisions,2X69B@28221|Deltaproteobacteria,2MSKC@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_4953527_12	1267533.KB906737_gene1727	6.438e-51	206.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,MASE1,PAS,PAS_3,PAS_4,PAS_9,Peripla_BP_3,Response_reg,dCache_2
LZS3_k127_4953527_21	667632.KB890194_gene3502	2.766e-22	113.0	COG0840@1|root,COG4251@1|root,COG0840@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VJGY@28216|Betaproteobacteria,1KGEK@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_9,TarH
LZS3_k127_4953527_26	204669.Acid345_1853	8.721e-11	70.0	2EBAA@1|root,335AW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
LZS3_k127_4953527_14	1379698.RBG1_1C00001G0781	8.34e-43	161.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
LZS3_k127_4953527_2	1379698.RBG1_1C00001G0780	2.676e-132	431.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
LZS3_k127_4953527_6	671143.DAMO_0822	3.007e-107	373.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
LZS3_k127_4953527_15	1125863.JAFN01000001_gene1841	1.115e-41	171.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
LZS3_k127_4953527_1	204669.Acid345_2710	1.609e-134	437.0	COG0535@1|root,COG0641@1|root,COG0535@2|Bacteria,COG0641@2|Bacteria,3Y2KT@57723|Acidobacteria,2JIDX@204432|Acidobacteriia	204432|Acidobacteriia	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS3_k127_4953527_3	234267.Acid_3343	4.132e-127	423.0	COG4948@1|root,COG4948@2|Bacteria,3Y61U@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_4953527_8	1267535.KB906767_gene2720	7.762e-85	298.0	COG0673@1|root,COG0673@2|Bacteria,3Y66I@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_4953527_13	720555.BATR1942_19875	2.434e-50	194.0	COG0329@1|root,COG0329@2|Bacteria,1UHED@1239|Firmicutes,4HAUA@91061|Bacilli,1ZASZ@1386|Bacillus	91061|Bacilli	EM	5-dehydro-4-deoxyglucarate dehydratase activity	ycbC	-	4.2.1.41	ko:K01707	ko00053,ko01100,map00053,map01100	-	R02279	RC00678	ko00000,ko00001,ko01000	-	-	-	DHDPS
LZS3_k127_4953527_10	234267.Acid_1540	1.828e-66	235.0	COG4798@1|root,COG4798@2|Bacteria,3Y5JR@57723|Acidobacteria	57723|Acidobacteria	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
LZS3_k127_4953527_27	926550.CLDAP_28810	1.051e-07	57.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
LZS3_k127_4972382_14	1340493.JNIF01000003_gene1333	7.317e-35	148.0	COG4963@1|root,COG4963@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
LZS3_k127_4972382_12	234267.Acid_6428	2.461e-53	191.0	COG0590@1|root,COG0590@2|Bacteria,3Y4KB@57723|Acidobacteria	57723|Acidobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	DUF3175,MafB19-deam
LZS3_k127_4972382_4	234267.Acid_1820	1.252e-155	503.0	COG2271@1|root,COG2271@2|Bacteria,3Y6PG@57723|Acidobacteria	57723|Acidobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_4972382_10	234267.Acid_4223	1.417e-86	291.0	COG0307@1|root,COG0307@2|Bacteria,3Y4EE@57723|Acidobacteria	57723|Acidobacteria	H	riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
LZS3_k127_4972382_9	234267.Acid_4123	4.743e-95	328.0	COG3307@1|root,COG3307@2|Bacteria,3Y67G@57723|Acidobacteria	57723|Acidobacteria	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS3_k127_4972382_8	1079460.ATTQ01000051_gene6378	6.197e-104	352.0	COG2041@1|root,COG2041@2|Bacteria,1QT0I@1224|Proteobacteria,2V9JK@28211|Alphaproteobacteria,4BGN1@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
LZS3_k127_4972382_17	348824.LPU83_4145	4.121e-24	107.0	2C19F@1|root,32ZRH@2|Bacteria,1NJ8W@1224|Proteobacteria,2V4D2@28211|Alphaproteobacteria,4BFUV@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972382_3	344747.PM8797T_15706	5.697e-182	581.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_4972382_18	90371.CY43_14860	1.263e-08	66.0	2EE8J@1|root,33831@2|Bacteria,1ND96@1224|Proteobacteria,1SED2@1236|Gammaproteobacteria,3ZMT1@590|Salmonella	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972382_11	1085623.GNIT_2999	1.571e-86	294.0	COG0428@1|root,COG0428@2|Bacteria,1PMN8@1224|Proteobacteria,1TKCY@1236|Gammaproteobacteria,46BX1@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
LZS3_k127_4972382_16	401053.AciPR4_4195	1.865e-30	131.0	COG3509@1|root,COG3509@2|Bacteria,3Y3SY@57723|Acidobacteria,2JKA4@204432|Acidobacteriia	204432|Acidobacteriia	Q	Carbohydrate-binding family 9	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
LZS3_k127_4972382_5	1267535.KB906767_gene2982	1.791e-143	484.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
LZS3_k127_4972382_0	234267.Acid_5546	1.901e-224	722.0	COG1024@1|root,COG1250@1|root,COG3033@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,COG3033@2|Bacteria,3Y2RB@57723|Acidobacteria	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
LZS3_k127_4972382_6	234267.Acid_0771	1.097e-129	424.0	COG0763@1|root,COG0763@2|Bacteria,3Y34H@57723|Acidobacteria	57723|Acidobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
LZS3_k127_4972382_1	234267.Acid_0772	2.965e-217	694.0	COG0308@1|root,COG0457@1|root,COG0308@2|Bacteria,COG0457@2|Bacteria,3Y3C5@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1,TPR_11,TPR_16
LZS3_k127_4972382_15	504728.K649_10275	1.739e-34	139.0	COG1943@1|root,COG1943@2|Bacteria,1WKUD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972382_7	1173026.Glo7428_3832	1.281e-122	412.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG5278@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG5278@2|Bacteria,1FZWU@1117|Cyanobacteria	1117|Cyanobacteria	T	Diguanylate cyclase with PAS PAC and GAF sensors	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_4,PAS_9
LZS3_k127_4972382_2	478741.JAFS01000001_gene1421	3.347e-196	625.0	COG0146@1|root,COG0146@2|Bacteria,46UMR@74201|Verrucomicrobia,37G2Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	EQ	Hydantoinase B/oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
LZS3_k127_4972382_13	1232410.KI421424_gene1799	4.214e-40	154.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,42NFP@68525|delta/epsilon subdivisions,2WK64@28221|Deltaproteobacteria,43SUE@69541|Desulfuromonadales	28221|Deltaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
LZS3_k127_5037012_2	378806.STAUR_3356	9.638e-31	133.0	COG3509@1|root,COG3509@2|Bacteria,1PI9N@1224|Proteobacteria,439C2@68525|delta/epsilon subdivisions,2X4K6@28221|Deltaproteobacteria,2YVGR@29|Myxococcales	28221|Deltaproteobacteria	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
LZS3_k127_5037012_4	582402.Hbal_2373	7.065e-09	68.0	COG0726@1|root,COG0726@2|Bacteria,1RBMV@1224|Proteobacteria,2URX3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS3_k127_5037012_3	309801.trd_A0610	4.436e-12	77.0	COG1506@1|root,COG1506@2|Bacteria,2G8QF@200795|Chloroflexi,27YT1@189775|Thermomicrobia	189775|Thermomicrobia	E	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
LZS3_k127_5037012_0	1340493.JNIF01000003_gene4574	4.193e-166	535.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_5037012_1	1123508.JH636446_gene6327	1.936e-84	291.0	COG4654@1|root,COG4654@2|Bacteria,2J55W@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
LZS3_k127_504993_2	686340.Metal_2759	5.421e-65	232.0	COG1018@1|root,COG1018@2|Bacteria,1RAS4@1224|Proteobacteria,1SXIT@1236|Gammaproteobacteria,1XG2E@135618|Methylococcales	135618|Methylococcales	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_1
LZS3_k127_504993_0	105559.Nwat_1376	2.987e-276	867.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS3_k127_504993_1	1267535.KB906767_gene221	1.833e-69	248.0	COG1082@1|root,COG1082@2|Bacteria,3Y65C@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_504993_4	1267535.KB906767_gene221	3.881e-57	212.0	COG1082@1|root,COG1082@2|Bacteria,3Y65C@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_504993_6	4641.GSMUA_Achr11P09960_001	7.288e-06	59.0	COG0457@1|root,KOG1124@2759|Eukaryota,37Q48@33090|Viridiplantae,3GA62@35493|Streptophyta,3KM8F@4447|Liliopsida	35493|Streptophyta	CO	Tetratricopeptide repeat	-	GO:0003002,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0008150,GO:0009628,GO:0009719,GO:0009725,GO:0009733,GO:0009734,GO:0009741,GO:0009742,GO:0009755,GO:0009987,GO:0010033,GO:0010051,GO:0010305,GO:0014070,GO:0023052,GO:0032501,GO:0032502,GO:0032870,GO:0033993,GO:0042221,GO:0043401,GO:0048545,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071310,GO:0071365,GO:0071367,GO:0071383,GO:0071396,GO:0071407,GO:0071495,GO:1901700,GO:1901701	-	ko:K09527	-	-	-	-	ko00000,ko03110	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8,Thioredoxin
LZS3_k127_504993_3	1123242.JH636434_gene5244	1.968e-59	229.0	2E55N@1|root,32ZYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_504993_5	1268072.PSAB_21170	8.514e-39	161.0	COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,2750F@186822|Paenibacillaceae	91061|Bacilli	E	Peptidase dimerisation domain	dapE_3	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS3_k127_5052879_6	237368.SCABRO_01838	5.135e-44	163.0	COG3741@1|root,COG3741@2|Bacteria	2|Bacteria	E	N-formylglutamate amidohydrolase	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
LZS3_k127_5052879_5	1123508.JH636448_gene7663	7.544e-67	237.0	COG1402@1|root,COG1402@2|Bacteria,2IYP1@203682|Planctomycetes	203682|Planctomycetes	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
LZS3_k127_5052879_0	1128421.JAGA01000002_gene1399	1.996e-168	540.0	COG1032@1|root,COG1032@2|Bacteria,2NQJQ@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS3_k127_5052879_2	290397.Adeh_2440	8.21e-115	383.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
LZS3_k127_5052879_4	234267.Acid_2237	1.206e-76	262.0	COG0279@1|root,COG0279@2|Bacteria,3Y7D7@57723|Acidobacteria	57723|Acidobacteria	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
LZS3_k127_5052879_3	234267.Acid_3554	1.346e-105	353.0	COG2870@1|root,COG2870@2|Bacteria,3Y680@57723|Acidobacteria	57723|Acidobacteria	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS3_k127_5052879_1	1267535.KB906767_gene3575	4.619e-153	489.0	COG1915@1|root,COG1915@2|Bacteria,3Y7FB@57723|Acidobacteria	57723|Acidobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5052879_8	497964.CfE428DRAFT_4947	3.402e-20	96.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
LZS3_k127_5052879_7	1210884.HG799465_gene11439	2.959e-22	100.0	COG0438@1|root,COG0438@2|Bacteria,2IXZX@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_50787_0	1340493.JNIF01000003_gene3297	1.602e-208	656.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria	57723|Acidobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS3_k127_50787_3	1340493.JNIF01000003_gene3296	7.361e-72	257.0	COG4963@1|root,COG4963@2|Bacteria,3Y44H@57723|Acidobacteria	57723|Acidobacteria	U	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
LZS3_k127_50787_4	1340493.JNIF01000003_gene3294	2.043e-53	199.0	COG3745@1|root,COG3745@2|Bacteria,3Y4HR@57723|Acidobacteria	57723|Acidobacteria	U	PFAM SAF domain	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
LZS3_k127_50787_5	1340493.JNIF01000004_gene207	2.645e-37	150.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02479,ko:K07684,ko:K07685	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS3_k127_50787_1	234267.Acid_4757	2.353e-144	464.0	COG0492@1|root,COG0492@2|Bacteria,3Y2NX@57723|Acidobacteria	57723|Acidobacteria	O	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
LZS3_k127_50787_2	234267.Acid_3050	3.585e-90	301.0	COG2318@1|root,COG2318@2|Bacteria,3Y73Z@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
LZS3_k127_5090743_2	234267.Acid_0432	4.181e-174	557.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
LZS3_k127_5090743_1	234267.Acid_0431	4.291e-175	568.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
LZS3_k127_5090743_0	234267.Acid_5023	5.335e-199	641.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5090743_6	234267.Acid_7896	8.214e-93	314.0	COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS3_k127_5090743_4	234267.Acid_7895	8.92e-134	449.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5090743_5	234267.Acid_7894	7.532e-94	322.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
LZS3_k127_5090743_3	344747.PM8797T_05420	2.693e-173	552.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5107981_1	1131269.AQVV01000014_gene194	2.642e-203	644.0	COG1008@1|root,COG1008@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoM	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
LZS3_k127_5107981_3	1265313.HRUBRA_02426	1.933e-187	608.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1J4U3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CP	CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	nuoL	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2278,iAF1260.b2278,iBWG_1329.BWG_2052,iECDH10B_1368.ECDH10B_2440,iECDH1ME8569_1439.ECDH1ME8569_2215,iEcDH1_1363.EcDH1_1379,iJN746.PP_4129,iJO1366.b2278,iJR904.b2278,iY75_1357.Y75_RS11945	Proton_antipo_M,Proton_antipo_N
LZS3_k127_5107981_5	1265313.HRUBRA_02425	2.348e-147	481.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RQBG@1236|Gammaproteobacteria,1J4RJ@118884|unclassified Gammaproteobacteria	1224|Proteobacteria	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
LZS3_k127_5107981_20	1265313.HRUBRA_02424	2.284e-44	164.0	COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria	1224|Proteobacteria	P	COG1006 Multisubunit Na H antiporter, MnhC subunit	mnhC	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
LZS3_k127_5107981_18	1265313.HRUBRA_02423	3.156e-50	183.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria	1224|Proteobacteria	P	Na H antiporter, MnhB	mnhB	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
LZS3_k127_5107981_14	1265313.HRUBRA_02422	9.051e-63	220.0	COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria	2|Bacteria	P	Na H antiporter, MnhB	mnhB	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB
LZS3_k127_5107981_23	1265313.HRUBRA_02421	1.251e-28	117.0	COG1320@1|root,COG1320@2|Bacteria	2|Bacteria	P	monovalent cation:proton antiporter activity	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
LZS3_k127_5107981_22	1265313.HRUBRA_02420	1.144e-32	129.0	COG2212@1|root,COG2212@2|Bacteria,1N2PU@1224|Proteobacteria	1224|Proteobacteria	P	Pfam Multiple resistance and pH regulation protein F	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
LZS3_k127_5107981_21	1131269.AQVV01000014_gene186	9.083e-33	132.0	COG1863@1|root,COG1863@2|Bacteria	2|Bacteria	P	multisubunit Na H antiporter MnhE subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
LZS3_k127_5107981_0	1131269.AQVV01000014_gene185	0.0	1200.0	COG3002@1|root,COG3002@2|Bacteria	2|Bacteria	P	Belongs to the UPF0753 family	-	-	-	ko:K09822	-	-	-	-	ko00000	-	-	-	DUF2309
LZS3_k127_5107981_2	237368.SCABRO_01609	1.081e-200	640.0	COG0659@1|root,COG0659@2|Bacteria,2IXYR@203682|Planctomycetes	203682|Planctomycetes	P	Sulfate transporter family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
LZS3_k127_5107981_17	1121957.ATVL01000008_gene4538	4.364e-54	201.0	COG2067@1|root,COG2067@2|Bacteria,4NJB3@976|Bacteroidetes,47JGU@768503|Cytophagia	976|Bacteroidetes	I	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
LZS3_k127_5107981_4	261292.Nit79A3_1298	2.389e-148	480.0	COG0425@1|root,COG0425@2|Bacteria,1R8DP@1224|Proteobacteria,2WFJB@28216|Betaproteobacteria,373Y3@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	AurF
LZS3_k127_5107981_7	261292.Nit79A3_1297	1.232e-122	400.0	COG3221@1|root,COG3221@2|Bacteria,1N92V@1224|Proteobacteria,2WBUH@28216|Betaproteobacteria,373TX@32003|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
LZS3_k127_5107981_6	261292.Nit79A3_1296	4.773e-139	454.0	COG1960@1|root,COG1960@2|Bacteria,1R9RG@1224|Proteobacteria,2WDMG@28216|Betaproteobacteria,3745S@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_5107981_16	886293.Sinac_7584	3.668e-60	224.0	COG0715@1|root,COG0715@2|Bacteria,2IX2Y@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
LZS3_k127_5107981_11	926566.Terro_3979	5.881e-74	265.0	COG0520@1|root,COG0520@2|Bacteria,3Y3UN@57723|Acidobacteria,2JK05@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
LZS3_k127_5107981_9	383372.Rcas_3855	5.549e-110	369.0	COG4948@1|root,COG4948@2|Bacteria,2G83T@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_5107981_15	1499680.CCFE01000021_gene2037	4.517e-61	222.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,1ZHG0@1386|Bacillus	91061|Bacilli	EH	Acetohydroxy acid isomeroreductase, NADPH-binding domain	serA3	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_5107981_12	1340493.JNIF01000004_gene1119	2.522e-67	238.0	COG0451@1|root,COG0451@2|Bacteria,3Y95U@57723|Acidobacteria	57723|Acidobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_5107981_8	278963.ATWD01000002_gene751	3.051e-111	377.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
LZS3_k127_5107981_13	292459.STH1014	7.713e-67	247.0	COG0028@1|root,COG0028@2|Bacteria,1UYHG@1239|Firmicutes,24FP1@186801|Clostridia	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_5107981_10	1340493.JNIF01000003_gene3109	4.532e-94	311.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_517884_1	204669.Acid345_3040	2.656e-49	179.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS3_k127_517884_0	913865.DOT_4956	4.701e-142	462.0	COG0668@1|root,COG0668@2|Bacteria,1TSHU@1239|Firmicutes,249AB@186801|Clostridia,26155@186807|Peptococcaceae	186801|Clostridia	M	Mechanosensitive ion channel	-	-	-	ko:K16053	-	-	-	-	ko00000,ko02000	1.A.23.4.5	-	-	MS_channel
LZS3_k127_517884_3	234267.Acid_2717	4.624e-14	81.0	28TDW@1|root,2ZFN7@2|Bacteria,3Y8WA@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_517884_2	1340493.JNIF01000003_gene2990	6.094e-48	178.0	2FERC@1|root,346QE@2|Bacteria,3Y8RE@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5283987_0	234267.Acid_6302	1.11e-117	388.0	COG1216@1|root,COG1216@2|Bacteria,3Y5FE@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_5283987_1	234267.Acid_6301	8.692e-97	329.0	COG2227@1|root,COG2227@2|Bacteria,3Y8XU@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
LZS3_k127_5283987_3	234267.Acid_6300	1.294e-71	248.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25,Methyltransf_31,TehB
LZS3_k127_5283987_2	1267535.KB906767_gene4620	3.991e-77	268.0	COG2234@1|root,COG2234@2|Bacteria,3Y406@57723|Acidobacteria,2JIRZ@204432|Acidobacteriia	204432|Acidobacteriia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS3_k127_5283987_4	1134912.AJTV01000002_gene1748	1.053e-56	208.0	2AC8B@1|root,311T0@2|Bacteria,1NK0P@1224|Proteobacteria,2VD5M@28211|Alphaproteobacteria,3713U@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5283987_5	926550.CLDAP_33250	2.858e-23	106.0	COG5485@1|root,COG5485@2|Bacteria,2G7DA@200795|Chloroflexi	200795|Chloroflexi	P	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
LZS3_k127_5291007_2	234267.Acid_7718	6.739e-191	621.0	COG1193@1|root,COG1193@2|Bacteria,3Y2Z2@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
LZS3_k127_5291007_10	1382359.JIAL01000001_gene2746	2.219e-49	179.0	COG1051@1|root,COG1051@2|Bacteria,3Y5BM@57723|Acidobacteria,2JJTC@204432|Acidobacteriia	204432|Acidobacteriia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
LZS3_k127_5291007_3	1267535.KB906767_gene984	2.904e-143	466.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
LZS3_k127_5291007_1	1499967.BAYZ01000139_gene157	1.027e-259	825.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS3_k127_5291007_7	234267.Acid_7054	3.311e-100	336.0	COG0077@1|root,COG0077@2|Bacteria,3Y49H@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
LZS3_k127_5291007_6	562970.Btus_1769	5.019e-118	397.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
LZS3_k127_5291007_8	1267535.KB906767_gene1028	3.234e-75	266.0	COG1559@1|root,COG1559@2|Bacteria,3Y2RD@57723|Acidobacteria,2JIQ0@204432|Acidobacteriia	204432|Acidobacteriia	M	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
LZS3_k127_5291007_11	234267.Acid_7012	2.487e-43	162.0	COG0816@1|root,COG0816@2|Bacteria,3Y59A@57723|Acidobacteria	57723|Acidobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
LZS3_k127_5291007_4	1267535.KB906767_gene4530	2.12e-140	458.0	COG3875@1|root,COG3875@2|Bacteria,3Y6SH@57723|Acidobacteria,2JKUN@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
LZS3_k127_5291007_9	234267.Acid_6700	3.582e-75	260.0	COG0266@1|root,COG0266@2|Bacteria,3Y39U@57723|Acidobacteria	57723|Acidobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
LZS3_k127_5291007_13	861299.J421_1875	3.663e-12	75.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
LZS3_k127_5291007_5	1403819.BATR01000090_gene2617	1.129e-137	454.0	COG1520@1|root,COG1520@2|Bacteria,46TM3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_5291007_0	886293.Sinac_7042	0.0	1158.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
LZS3_k127_5291007_12	234267.Acid_6535	4.765e-35	140.0	COG1082@1|root,COG1082@2|Bacteria,3Y65C@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_5298889_10	1121939.L861_02680	6.021e-26	111.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.3.6,6.3.5.4	ko:K01953,ko:K18316	ko00250,ko00332,ko01100,ko01110,ko01130,ko02024,map00250,map00332,map01100,map01110,map01130,map02024	M00675	R00578,R10556	RC00010,RC03195	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Asn_synthase,DUF1933,GATase_7
LZS3_k127_5298889_2	1123508.JH636439_gene1018	7.459e-146	470.0	COG3391@1|root,COG3391@2|Bacteria,2J27D@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS3_k127_5298889_5	1210884.HG799462_gene7948	6.437e-58	212.0	COG4785@1|root,COG4785@2|Bacteria,2IZYN@203682|Planctomycetes	203682|Planctomycetes	S	May be involved in cell division	-	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_16
LZS3_k127_5298889_0	886293.Sinac_1739	1.276e-255	825.0	COG2010@1|root,COG2010@2|Bacteria,2IXBU@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
LZS3_k127_5298889_1	497964.CfE428DRAFT_6606	8.885e-217	683.0	COG1368@1|root,COG1368@2|Bacteria	2|Bacteria	M	sulfuric ester hydrolase activity	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	PMT_2,Sulfatase,Wzy_C
LZS3_k127_5298889_12	344747.PM8797T_21768	6.789e-05	49.0	COG2010@1|root,COG2010@2|Bacteria,2IXDW@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
LZS3_k127_5298889_3	234267.Acid_4804	1.433e-90	315.0	COG2008@1|root,COG2008@2|Bacteria,3Y7Q8@57723|Acidobacteria	57723|Acidobacteria	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS3_k127_5298889_8	935837.JAEK01000028_gene1814	7.067e-27	115.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,1ZHDQ@1386|Bacillus	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
LZS3_k127_5298889_6	1131814.JAFO01000001_gene2573	8.936e-52	185.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
LZS3_k127_5298889_11	420662.Mpe_A3023	5.78e-18	90.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2VHDW@28216|Betaproteobacteria,1KJUH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	AI-2E family transporter	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS3_k127_5298889_4	519989.ECTPHS_11984	1.193e-82	284.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,1RRWT@1236|Gammaproteobacteria,1WXVN@135613|Chromatiales	135613|Chromatiales	G	PfkB domain protein	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS3_k127_5298889_9	1267535.KB906767_gene5200	1.33e-26	113.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rpbA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_5298889_7	368407.Memar_1765	1.225e-51	187.0	COG1047@1|root,arCOG00981@2157|Archaea,2XXFW@28890|Euryarchaeota,2NAZY@224756|Methanomicrobia	224756|Methanomicrobia	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
LZS3_k127_5375162_5	344747.PM8797T_11229	2.502e-197	625.0	COG3119@1|root,COG3119@2|Bacteria,2IX69@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_5375162_22	234267.Acid_2219	1.571e-32	132.0	COG0784@1|root,COG0784@2|Bacteria,3Y4W5@57723|Acidobacteria	57723|Acidobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_5375162_12	234267.Acid_3917	1.809e-90	303.0	COG2220@1|root,COG2220@2|Bacteria,3Y4RK@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
LZS3_k127_5375162_9	204669.Acid345_2780	4.872e-101	342.0	COG1820@1|root,COG1820@2|Bacteria,3Y3NQ@57723|Acidobacteria,2JIST@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
LZS3_k127_5375162_10	234267.Acid_7426	1.328e-96	325.0	COG2103@1|root,COG2103@2|Bacteria,3Y378@57723|Acidobacteria	57723|Acidobacteria	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS_2
LZS3_k127_5375162_6	234267.Acid_4783	1.324e-166	535.0	COG0531@1|root,COG0531@2|Bacteria,3Y2T1@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS3_k127_5375162_0	234267.Acid_3631	1.178e-273	864.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,3Y2UC@57723|Acidobacteria	57723|Acidobacteria	V	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF1343,SSF
LZS3_k127_5375162_4	264732.Moth_1850	1.349e-200	647.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
LZS3_k127_5375162_20	994573.T472_0219720	3.373e-46	175.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
LZS3_k127_5375162_14	1231185.BAMP01000054_gene4805	1.592e-76	270.0	COG1921@1|root,COG1921@2|Bacteria,1MW8F@1224|Proteobacteria,2TSR8@28211|Alphaproteobacteria,43RP0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	L-seryl-tRNA selenium transferase	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
LZS3_k127_5375162_23	622312.ROSEINA2194_00031	2.607e-28	118.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia	186801|Clostridia	S	THIoesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
LZS3_k127_5375162_19	1267534.KB906754_gene2561	5.892e-47	173.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	2.3.1.82	ko:K03830,ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS3_k127_5375162_1	1340493.JNIF01000004_gene294	3.925e-240	756.0	COG0591@1|root,COG0591@2|Bacteria,3Y4WN@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS3_k127_5375162_17	102129.Lepto7375DRAFT_6681	9.023e-62	220.0	COG1846@1|root,COG1846@2|Bacteria,1G6G4@1117|Cyanobacteria,1HGTR@1150|Oscillatoriales	1117|Cyanobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
LZS3_k127_5375162_11	472759.Nhal_2068	6.593e-96	316.0	arCOG04078@1|root,2Z8UN@2|Bacteria,1NUZV@1224|Proteobacteria,1SNQJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protoglobin	-	-	-	-	-	-	-	-	-	-	-	-	Protoglobin
LZS3_k127_5375162_15	1449063.JMLS01000003_gene2005	3.322e-64	236.0	COG0823@1|root,COG0823@2|Bacteria,1V8I5@1239|Firmicutes,4HSYG@91061|Bacilli,26UTS@186822|Paenibacillaceae	1239|Firmicutes	U	Oligogalacturonate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase22
LZS3_k127_5375162_8	1123368.AUIS01000004_gene245	9.401e-141	464.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,2NCQ4@225057|Acidithiobacillales	225057|Acidithiobacillales	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
LZS3_k127_5375162_7	616991.JPOO01000001_gene4353	1.918e-156	520.0	COG2091@1|root,COG2091@2|Bacteria,4NFQ6@976|Bacteroidetes,1HZHJ@117743|Flavobacteriia,23GZ2@178469|Arenibacter	976|Bacteroidetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
LZS3_k127_5375162_2	234267.Acid_3122	4.213e-230	726.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	2|Bacteria	G	PQQ-like domain	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
LZS3_k127_5375162_18	234267.Acid_3123	8.07e-60	218.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_5375162_21	886293.Sinac_3180	6.661e-42	165.0	COG0671@1|root,COG0671@2|Bacteria,2J3BG@203682|Planctomycetes	203682|Planctomycetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5375162_24	234267.Acid_1557	5.786e-27	120.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,TPR_8
LZS3_k127_5375162_3	1267535.KB906767_gene1708	1.535e-224	707.0	COG1032@1|root,COG1032@2|Bacteria,3Y2V1@57723|Acidobacteria,2JKBR@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS3_k127_5375162_13	234267.Acid_6627	3.723e-85	294.0	COG0500@1|root,COG2226@2|Bacteria,3Y46W@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_5382184_3	1340493.JNIF01000003_gene3109	2.735e-75	260.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_5382184_1	1123368.AUIS01000023_gene925	7.658e-129	421.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,1RMRD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS3_k127_5382184_2	1210884.HG799474_gene15182	6.546e-82	278.0	COG1136@1|root,COG1136@2|Bacteria,2IZ2X@203682|Planctomycetes	203682|Planctomycetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
LZS3_k127_5382184_0	1340493.JNIF01000003_gene2854	2.138e-132	432.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_54003_2	479434.Sthe_3482	1.886e-95	317.0	COG2041@1|root,COG2041@2|Bacteria,2GB1N@200795|Chloroflexi,27Z7Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
LZS3_k127_54003_3	595460.RRSWK_03276	1.514e-71	260.0	COG0642@1|root,COG2205@2|Bacteria,2J565@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_54003_4	215803.DB30_6335	4.524e-59	209.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42VIG@68525|delta/epsilon subdivisions,2WS98@28221|Deltaproteobacteria,2YV93@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_54003_0	1173028.ANKO01000056_gene2163	5.897e-127	452.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1HH3F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
LZS3_k127_54003_1	1124780.ANNU01000063_gene608	1.476e-103	381.0	COG1409@1|root,COG2133@1|root,COG3291@1|root,COG3488@1|root,COG4932@1|root,COG1409@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3488@2|Bacteria,COG4932@2|Bacteria,4NG9B@976|Bacteroidetes,47U64@768503|Cytophagia	976|Bacteroidetes	CG	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,PKD
LZS3_k127_54003_5	526222.Desal_0888	5.957e-28	134.0	COG1404@1|root,COG1404@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria,2MAVV@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
LZS3_k127_5452110_1	105559.Nwat_1376	9.372e-311	958.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS3_k127_5452110_4	1266908.AQPB01000033_gene1661	2.433e-14	81.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,1RS4U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glucoamylase and related glycosyl hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
LZS3_k127_5452110_2	234267.Acid_7221	1.044e-99	340.0	COG2271@1|root,COG2271@2|Bacteria,3Y2VG@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
LZS3_k127_5452110_3	991905.SL003B_3944	7.904e-51	194.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,2TTSG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	beta-lactamase	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
LZS3_k127_5452110_5	744872.Spica_2485	0.0002146	49.0	COG2204@1|root,COG2204@2|Bacteria,2J5NY@203691|Spirochaetes	203691|Spirochaetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_5452110_0	118168.MC7420_603	2.29e-321	1004.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1HAES@1150|Oscillatoriales	1117|Cyanobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
LZS3_k127_5480987_13	204669.Acid345_1853	8.096e-15	83.0	2EBAA@1|root,335AW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
LZS3_k127_5480987_10	234267.Acid_1213	3.871e-27	114.0	COG2127@1|root,COG2127@2|Bacteria,3Y85A@57723|Acidobacteria	57723|Acidobacteria	S	ATP-dependent Clp protease adaptor protein ClpS	-	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
LZS3_k127_5480987_0	204669.Acid345_3965	4.014e-233	749.0	COG0557@1|root,COG0557@2|Bacteria,3Y3TF@57723|Acidobacteria,2JIM3@204432|Acidobacteriia	204432|Acidobacteriia	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
LZS3_k127_5480987_4	439235.Dalk_0155	1.515e-83	287.0	COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,42NRY@68525|delta/epsilon subdivisions,2WJBD@28221|Deltaproteobacteria,2MHY7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
LZS3_k127_5480987_8	366602.Caul_2370	3.538e-50	193.0	COG2819@1|root,COG2819@2|Bacteria,1RB1X@1224|Proteobacteria,2U9NE@28211|Alphaproteobacteria,2KJ56@204458|Caulobacterales	204458|Caulobacterales	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
LZS3_k127_5480987_5	1267535.KB906767_gene4329	4.528e-78	266.0	COG0807@1|root,COG0807@2|Bacteria,3Y2I4@57723|Acidobacteria,2JHSG@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydro2
LZS3_k127_5480987_1	234267.Acid_2181	1.051e-130	432.0	COG2972@1|root,COG2972@2|Bacteria,3Y3NH@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase internal region	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,HATPase_c,His_kinase
LZS3_k127_5480987_2	204669.Acid345_0343	1.524e-98	335.0	COG1085@1|root,COG1085@2|Bacteria,3Y41K@57723|Acidobacteria,2JMKJ@204432|Acidobacteriia	204432|Acidobacteriia	C	Domain of unknown function (DUF4921)	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C
LZS3_k127_5480987_9	297246.lpp0851	1.538e-44	168.0	COG1943@1|root,COG1943@2|Bacteria,1QC63@1224|Proteobacteria,1T7V3@1236|Gammaproteobacteria,1JFWA@118969|Legionellales	118969|Legionellales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
LZS3_k127_5480987_11	234267.Acid_2433	4.311e-25	111.0	COG0792@1|root,COG0792@2|Bacteria,3Y56J@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
LZS3_k127_5480987_3	1340493.JNIF01000004_gene222	5.563e-84	289.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	2|Bacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_5480987_6	293826.Amet_0505	6.967e-61	222.0	COG3836@1|root,COG3836@2|Bacteria,1UZZG@1239|Firmicutes,24DTX@186801|Clostridia,36JVT@31979|Clostridiaceae	186801|Clostridia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
LZS3_k127_5480987_7	1340493.JNIF01000003_gene3494	1.193e-59	214.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.102	ko:K06978,ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	AXE1,Big_5,LTD,Peptidase_S9,Tannase
LZS3_k127_5482653_1	234267.Acid_0755	6.685e-175	557.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria	57723|Acidobacteria	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
LZS3_k127_5482653_6	1340493.JNIF01000003_gene1671	6.349e-32	127.0	COG1977@1|root,COG1977@2|Bacteria,3Y546@57723|Acidobacteria	57723|Acidobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS3_k127_5482653_5	1267535.KB906767_gene1048	4.343e-58	208.0	COG1310@1|root,COG1310@2|Bacteria,3Y4PH@57723|Acidobacteria	57723|Acidobacteria	S	Mov34 MPN PAD-1	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
LZS3_k127_5482653_2	234267.Acid_0758	1.266e-129	421.0	COG0031@1|root,COG0031@2|Bacteria,3Y39M@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_5482653_4	1340493.JNIF01000003_gene3795	7.147e-91	310.0	COG1028@1|root,COG1028@2|Bacteria,3Y67C@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
LZS3_k127_5482653_0	1123242.JH636436_gene121	3.604e-178	583.0	COG4122@1|root,COG4122@2|Bacteria,2IXSM@203682|Planctomycetes	203682|Planctomycetes	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5482653_3	1122605.KB893637_gene3269	4.327e-93	333.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
LZS3_k127_5499975_8	1125863.JAFN01000001_gene2973	2.035e-18	88.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,42VWR@68525|delta/epsilon subdivisions,2WS4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
LZS3_k127_5499975_0	234267.Acid_4151	0.0	1388.0	COG0841@1|root,COG0841@2|Bacteria,3Y2SK@57723|Acidobacteria	57723|Acidobacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS3_k127_5499975_5	234267.Acid_4152	1.047e-75	270.0	COG0845@1|root,COG0845@2|Bacteria,3Y4YK@57723|Acidobacteria	57723|Acidobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS3_k127_5499975_4	234267.Acid_4153	1.38e-101	347.0	COG1538@1|root,COG1538@2|Bacteria,3Y5F3@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_5499975_6	589865.DaAHT2_2101	2.822e-32	128.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ybzH	-	-	-	-	-	-	-	-	-	-	-	DUF43,HTH_20,HTH_5
LZS3_k127_5499975_7	330214.NIDE3895	1.333e-23	107.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	ymaD	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
LZS3_k127_5499975_2	1121468.AUBR01000045_gene1811	1.545e-124	415.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,42EYR@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
LZS3_k127_5499975_1	1267535.KB906767_gene5021	1.357e-208	655.0	COG0017@1|root,COG0017@2|Bacteria,3Y350@57723|Acidobacteria,2JI7K@204432|Acidobacteriia	204432|Acidobacteriia	J	class II (D K	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS3_k127_5499975_3	234267.Acid_2806	1.042e-104	346.0	COG1082@1|root,COG1082@2|Bacteria,3Y4EN@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_5500013_16	1267535.KB906767_gene290	5.799e-66	235.0	COG2948@1|root,COG2948@2|Bacteria,3Y6SY@57723|Acidobacteria	57723|Acidobacteria	U	multi-organism process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5500013_3	234267.Acid_3414	3.979e-166	548.0	COG5000@1|root,COG5000@2|Bacteria,3Y32D@57723|Acidobacteria	57723|Acidobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8
LZS3_k127_5500013_1	234267.Acid_3413	1.825e-210	663.0	COG2204@1|root,COG2204@2|Bacteria,3Y2J1@57723|Acidobacteria	57723|Acidobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_5500013_17	1120950.KB892753_gene6102	6.85e-57	207.0	COG4813@1|root,COG4813@2|Bacteria,2I8EC@201174|Actinobacteria,4DTRT@85009|Propionibacteriales	2|Bacteria	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
LZS3_k127_5500013_4	234267.Acid_0484	1.846e-150	484.0	COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria	57723|Acidobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
LZS3_k127_5500013_18	1047013.AQSP01000128_gene453	2.128e-49	181.0	COG0509@1|root,COG0509@2|Bacteria,2NPMR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
LZS3_k127_5500013_2	234267.Acid_0482	1.928e-192	610.0	COG0403@1|root,COG0403@2|Bacteria,3Y2WZ@57723|Acidobacteria	57723|Acidobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS3_k127_5500013_0	234267.Acid_0481	9.199e-249	775.0	COG1003@1|root,COG1003@2|Bacteria,3Y2UZ@57723|Acidobacteria	57723|Acidobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS3_k127_5500013_5	234267.Acid_0480	8.164e-127	428.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_5500013_21	1340493.JNIF01000003_gene1793	4.662e-46	181.0	2EHBQ@1|root,33B3J@2|Bacteria,3Y7KU@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
LZS3_k127_5500013_20	706587.Desti_3511	1.227e-47	174.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
LZS3_k127_5500013_13	1047013.AQSP01000076_gene1470	3.108e-78	276.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_5500013_19	622637.KE124774_gene1497	3.571e-48	177.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2183 Transcriptional accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_5500013_7	639030.JHVA01000001_gene2540	3.391e-106	355.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_5500013_12	234267.Acid_7119	4.153e-86	295.0	COG1216@1|root,COG1216@2|Bacteria,3Y7YU@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5500013_14	234267.Acid_7120	1.736e-77	269.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
LZS3_k127_5500013_15	234267.Acid_4244	1.832e-68	249.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_5500013_6	1267535.KB906767_gene219	1.168e-109	364.0	COG3618@1|root,COG3618@2|Bacteria	2|Bacteria	H	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_5500013_10	479434.Sthe_3474	2.944e-88	305.0	COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi,27XRM@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS3_k127_5500013_9	479434.Sthe_3474	8.324e-93	322.0	COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi,27XRM@189775|Thermomicrobia	189775|Thermomicrobia	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS3_k127_5500013_22	1033802.SSPSH_000725	5.968e-45	170.0	COG0494@1|root,COG0494@2|Bacteria,1RI3B@1224|Proteobacteria,1S6HR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA mismatch repair protein MutT	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
LZS3_k127_5500013_11	760192.Halhy_5705	2.426e-86	290.0	COG1335@1|root,COG1335@2|Bacteria,4NKPP@976|Bacteroidetes,1IRUE@117747|Sphingobacteriia	976|Bacteroidetes	Q	Isochorismatase family	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
LZS3_k127_5500013_23	243233.MCA0776	2.483e-29	126.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
LZS3_k127_5500013_8	234267.Acid_1391	1.565e-96	333.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	CTP_transf_3,HNH_4,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS3_k127_5500013_25	1356852.N008_13115	2.36e-17	96.0	COG0166@1|root,COG0166@2|Bacteria	2|Bacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
LZS3_k127_550617_9	234267.Acid_7761	3.647e-29	123.0	2FHZ5@1|root,349S3@2|Bacteria,3Y8GI@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_550617_4	1340493.JNIF01000003_gene4303	9.71e-116	385.0	COG3616@1|root,COG3616@2|Bacteria,3Y7EX@57723|Acidobacteria	57723|Acidobacteria	E	Putative serine dehydratase domain	-	-	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
LZS3_k127_550617_8	234267.Acid_0591	1.005e-35	145.0	COG0251@1|root,COG0251@2|Bacteria,3Y5DN@57723|Acidobacteria	57723|Acidobacteria	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
LZS3_k127_550617_3	204669.Acid345_2796	1.097e-188	610.0	COG0493@1|root,COG0493@2|Bacteria,3Y3EA@57723|Acidobacteria,2JJCC@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	M00046	R00093,R00114,R00248,R00977,R01414,R10159,R11026	RC00006,RC00010,RC00072,RC00123,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
LZS3_k127_550617_6	204669.Acid345_2795	1.18e-83	286.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	gltA	-	1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,Pyr_redox_2
LZS3_k127_550617_7	1121957.ATVL01000006_gene2545	1.067e-63	224.0	COG1670@1|root,COG1670@2|Bacteria,4NMRH@976|Bacteroidetes,47QKT@768503|Cytophagia	976|Bacteroidetes	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
LZS3_k127_550617_2	1123248.KB893359_gene2156	6.907e-217	711.0	COG1413@1|root,COG2133@1|root,COG3474@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3474@2|Bacteria,4NGAU@976|Bacteroidetes,1IWXQ@117747|Sphingobacteriia	976|Bacteroidetes	CG	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS3_k127_550617_1	1340493.JNIF01000003_gene3160	5.57e-286	919.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941,ko:K06350	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D,SLH
LZS3_k127_550617_5	234267.Acid_7075	2.359e-104	357.0	COG0037@1|root,COG0037@2|Bacteria,3Y2F2@57723|Acidobacteria	57723|Acidobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
LZS3_k127_550617_0	234267.Acid_7074	2.766e-289	900.0	COG0465@1|root,COG0465@2|Bacteria,3Y2UK@57723|Acidobacteria	57723|Acidobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS3_k127_550617_12	118161.KB235922_gene589	7.428e-07	58.0	COG5305@1|root,COG5305@2|Bacteria,1G2NQ@1117|Cyanobacteria,3VIWI@52604|Pleurocapsales	1117|Cyanobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_5514848_7	1267535.KB906767_gene2008	5.39e-107	359.0	COG0845@1|root,COG0845@2|Bacteria,3Y2U2@57723|Acidobacteria,2JMFW@204432|Acidobacteriia	204432|Acidobacteriia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS3_k127_5514848_0	234267.Acid_5518	0.0	1125.0	COG0841@1|root,COG0841@2|Bacteria,3Y478@57723|Acidobacteria	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS3_k127_5514848_5	234267.Acid_5886	3.782e-113	381.0	COG1538@1|root,COG1538@2|Bacteria,3Y3KB@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_5514848_18	387631.Asulf_00825	8.431e-22	102.0	COG1695@1|root,arCOG00001@2157|Archaea,2Y0JW@28890|Euryarchaeota,24784@183980|Archaeoglobi	183980|Archaeoglobi	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
LZS3_k127_5514848_19	1121085.AUCI01000002_gene4020	1.796e-17	84.0	2BFS6@1|root,329M0@2|Bacteria,1UBZZ@1239|Firmicutes,4INFW@91061|Bacilli,1ZNF2@1386|Bacillus	91061|Bacilli	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
LZS3_k127_5514848_24	929713.NIASO_13265	0.0004646	47.0	28UGW@1|root,2ZGMQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5514848_16	859657.RPSI07_mp1307	7.142e-32	128.0	2EBPV@1|root,335PY@2|Bacteria,1NK03@1224|Proteobacteria,2VY2U@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1360
LZS3_k127_5514848_1	204669.Acid345_2336	2.222e-232	733.0	COG1032@1|root,COG1032@2|Bacteria,3Y7D8@57723|Acidobacteria,2JMKA@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS3_k127_5514848_10	278963.ATWD01000001_gene1668	8.348e-89	308.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria,2JI4A@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_5514848_15	1340493.JNIF01000003_gene1793	5.564e-38	158.0	2EHBQ@1|root,33B3J@2|Bacteria,3Y7KU@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
LZS3_k127_5514848_22	448385.sce4537	2.923e-10	71.0	COG0500@1|root,COG2226@2|Bacteria,1RASQ@1224|Proteobacteria,42QTY@68525|delta/epsilon subdivisions,2WMN2@28221|Deltaproteobacteria,2YWX8@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
LZS3_k127_5514848_23	573370.DMR_10870	1.241e-06	61.0	COG5305@1|root,COG5305@2|Bacteria,1NAW4@1224|Proteobacteria	1224|Proteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_5514848_13	1340493.JNIF01000003_gene3291	2.334e-63	226.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02479,ko:K07684,ko:K07685	ko02020,map02020	M00471,M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS3_k127_5514848_20	247490.KSU1_D0904	3.639e-15	89.0	COG1807@1|root,COG1807@2|Bacteria,2J1H1@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_5514848_6	1340493.JNIF01000003_gene3292	7.215e-112	381.0	COG1287@1|root,COG1287@2|Bacteria,3Y5FJ@57723|Acidobacteria	57723|Acidobacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5514848_17	1340493.JNIF01000003_gene3293	1.977e-28	120.0	COG1989@1|root,COG1989@2|Bacteria,3Y9FS@57723|Acidobacteria	57723|Acidobacteria	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
LZS3_k127_5514848_14	1340493.JNIF01000003_gene3294	4.129e-59	215.0	COG3745@1|root,COG3745@2|Bacteria,3Y4HR@57723|Acidobacteria	57723|Acidobacteria	U	PFAM SAF domain	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
LZS3_k127_5514848_4	1340493.JNIF01000003_gene3295	5.703e-122	407.0	COG4964@1|root,COG4964@2|Bacteria,3Y3DF@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the GSP D family	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
LZS3_k127_5514848_9	1340493.JNIF01000003_gene3296	1.633e-92	317.0	COG4963@1|root,COG4963@2|Bacteria,3Y44H@57723|Acidobacteria	57723|Acidobacteria	U	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
LZS3_k127_5514848_2	1340493.JNIF01000003_gene3297	1.57e-215	677.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria	57723|Acidobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS3_k127_5514848_11	1340493.JNIF01000003_gene3298	2.745e-84	290.0	COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria	57723|Acidobacteria	U	type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS3_k127_5514848_8	1340493.JNIF01000003_gene3299	7.586e-94	316.0	COG2064@1|root,COG2064@2|Bacteria,3Y4FI@57723|Acidobacteria	57723|Acidobacteria	NU	type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS3_k127_5514848_12	234267.Acid_2270	8.853e-67	247.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5536623_9	234267.Acid_2556	7.383e-32	126.0	COG2252@1|root,COG2252@2|Bacteria,3Y2I3@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Xanthine uracil vitamin C permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
LZS3_k127_5536623_8	243231.GSU0538	2.855e-34	136.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,43UXA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS3_k127_5536623_0	1382359.JIAL01000001_gene892	0.0	1101.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria,2JIAE@204432|Acidobacteriia	204432|Acidobacteriia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS3_k127_5536623_3	1123368.AUIS01000011_gene1139	4.13e-114	412.0	COG1404@1|root,COG1404@2|Bacteria,1R90Q@1224|Proteobacteria,1S01H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
LZS3_k127_5536623_7	234267.Acid_0422	3.597e-41	162.0	292F3@1|root,2ZPZC@2|Bacteria,3Y90G@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5536623_1	234267.Acid_5976	6.046e-232	740.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,3Y77C@57723|Acidobacteria	57723|Acidobacteria	G	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_2,WD40
LZS3_k127_5536623_6	234267.Acid_5978	2.677e-50	192.0	2EU62@1|root,33MNN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
LZS3_k127_5536623_5	42256.RradSPS_0023	1.85e-58	226.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,4CPU4@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS3_k127_5536623_12	1267535.KB906767_gene1596	6.351e-07	63.0	2A0FS@1|root,30NJK@2|Bacteria,3Y8KG@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5536623_2	234267.Acid_0227	8.198e-188	596.0	COG3522@1|root,COG3522@2|Bacteria,3Y3ZF@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
LZS3_k127_5556054_27	234267.Acid_4244	1.756e-05	47.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_5556054_16	1340493.JNIF01000003_gene2217	9.679e-66	232.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	2.3.1.157,2.7.7.13,2.7.7.23,5.4.2.8	ko:K04042,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00416,R00885,R01818,R05332	RC00002,RC00004,RC00166,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS3_k127_5556054_14	251229.Chro_2173	3.147e-70	249.0	COG3386@1|root,COG3386@2|Bacteria,1G2S8@1117|Cyanobacteria,3VMV4@52604|Pleurocapsales	1117|Cyanobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
LZS3_k127_5556054_10	1009370.ALO_18390	3.792e-114	382.0	COG1055@1|root,COG1055@2|Bacteria,1TRZC@1239|Firmicutes,4H1XG@909932|Negativicutes	909932|Negativicutes	P	Dicarboxylate carrier MatC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MatC_N
LZS3_k127_5556054_23	929712.KI912613_gene952	7.558e-28	116.0	COG1146@1|root,COG1146@2|Bacteria,2IKVN@201174|Actinobacteria,4CQEK@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
LZS3_k127_5556054_11	234267.Acid_2167	6.152e-112	375.0	COG0477@1|root,COG2814@2|Bacteria,3Y47I@57723|Acidobacteria	57723|Acidobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
LZS3_k127_5556054_9	69279.BG36_06490	8.295e-184	592.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,43J3W@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
LZS3_k127_5556054_18	1214101.BN159_4302	3.848e-49	183.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
LZS3_k127_5556054_17	1227453.C444_19322	1.228e-55	204.0	COG1402@1|root,arCOG04536@2157|Archaea,2XTXE@28890|Euryarchaeota,23T8H@183963|Halobacteria	183963|Halobacteria	H	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS3_k127_5556054_12	1382306.JNIM01000001_gene2592	6.811e-82	282.0	COG1028@1|root,COG1028@2|Bacteria,2G8S6@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_5556054_15	234267.Acid_6714	1.139e-68	239.0	COG0310@1|root,COG0310@2|Bacteria,3Y8I6@57723|Acidobacteria	57723|Acidobacteria	P	Cobalt uptake substrate-specific transmembrane region	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
LZS3_k127_5556054_26	1385518.N798_10985	3.108e-08	58.0	COG0310@1|root,COG0310@2|Bacteria,2GRUA@201174|Actinobacteria,4FHVG@85021|Intrasporangiaceae	201174|Actinobacteria	P	PDGLE domain	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	PDGLE
LZS3_k127_5556054_20	234267.Acid_6715	2.91e-45	172.0	COG0619@1|root,COG0619@2|Bacteria,3Y92N@57723|Acidobacteria	57723|Acidobacteria	P	Cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
LZS3_k127_5556054_13	234267.Acid_6716	2.995e-78	268.0	COG1122@1|root,COG1122@2|Bacteria,3Y84B@57723|Acidobacteria	57723|Acidobacteria	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
LZS3_k127_5556054_5	1040989.AWZU01000008_gene3770	4.931e-293	909.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2TRMQ@28211|Alphaproteobacteria,3JRQ3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
LZS3_k127_5556054_1	1232410.KI421426_gene1372	0.0	1104.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,42Q4Z@68525|delta/epsilon subdivisions,2WM28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase
LZS3_k127_5556054_8	472759.Nhal_3182	6.395e-186	595.0	COG0637@1|root,COG1554@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,COG1877@2|Bacteria,1MWJE@1224|Proteobacteria,1RPN6@1236|Gammaproteobacteria,1X03I@135613|Chromatiales	135613|Chromatiales	G	Glycosyl hydrolase family 65 central catalytic domain	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Trehalose_PPase
LZS3_k127_5556054_6	697282.Mettu_0566	1.118e-292	933.0	COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,1T1IP@1236|Gammaproteobacteria,1XDND@135618|Methylococcales	135618|Methylococcales	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
LZS3_k127_5556054_7	886293.Sinac_2834	3.788e-234	741.0	COG0296@1|root,COG0296@2|Bacteria,2IXPW@203682|Planctomycetes	203682|Planctomycetes	G	Alpha amylase, catalytic domain	-	-	3.2.1.1,3.2.1.141	ko:K01176,ko:K01236	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	M00565	R02108,R02112,R09995,R11256,R11262	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459,S6PP
LZS3_k127_5556054_3	247490.KSU1_C1305	3.852e-313	968.0	COG0296@1|root,COG0296@2|Bacteria,2IXS1@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
LZS3_k127_5556054_2	575540.Isop_2400	0.0	1067.0	COG1523@1|root,COG1523@2|Bacteria,2IX65@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
LZS3_k127_5556054_0	1267533.KB906739_gene2644	0.0	1406.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,3Y2RE@57723|Acidobacteria,2JHM7@204432|Acidobacteriia	204432|Acidobacteriia	G	Maltogenic Amylase, C-terminal domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
LZS3_k127_5556054_4	1173027.Mic7113_3737	8.86e-294	914.0	COG0296@1|root,COG0366@1|root,COG0296@2|Bacteria,COG0366@2|Bacteria,1G2ZI@1117|Cyanobacteria,1H9FE@1150|Oscillatoriales	1117|Cyanobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
LZS3_k127_5556054_22	661478.OP10G_2579	4.556e-30	132.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	slp	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
LZS3_k127_5556054_24	570952.ATVH01000014_gene2014	6.638e-27	114.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,2JTJ7@204441|Rhodospirillales	204441|Rhodospirillales	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
LZS3_k127_5556054_25	926549.KI421517_gene438	8.614e-26	115.0	2E7ZG@1|root,332DV@2|Bacteria,4P625@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4864)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4864
LZS3_k127_5556054_21	234267.Acid_7348	4.752e-32	130.0	COG4031@1|root,COG4031@2|Bacteria,3Y8JK@57723|Acidobacteria	57723|Acidobacteria	S	Predicted metal-binding protein (DUF2103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2103
LZS3_k127_5556054_19	1340493.JNIF01000003_gene4321	9.144e-48	173.0	COG2234@1|root,COG2234@2|Bacteria,3Y4CJ@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS3_k127_5565904_3	1267535.KB906767_gene444	3.867e-108	359.0	COG0673@1|root,COG0673@2|Bacteria,3Y4BF@57723|Acidobacteria,2JKZN@204432|Acidobacteriia	204432|Acidobacteriia	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5565904_5	204669.Acid345_2208	3.04e-79	271.0	COG0302@1|root,COG0302@2|Bacteria,3Y2SP@57723|Acidobacteria,2JIR1@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
LZS3_k127_5565904_9	1267535.KB906767_gene3987	1.206e-40	154.0	COG0720@1|root,COG0720@2|Bacteria,3Y56Y@57723|Acidobacteria,2JJNB@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM 6-pyruvoyl tetrahydropterin	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
LZS3_k127_5565904_6	234267.Acid_1563	1.646e-54	194.0	COG0720@1|root,COG0720@2|Bacteria,3Y4K2@57723|Acidobacteria	57723|Acidobacteria	H	PFAM 6-pyruvoyl tetrahydropterin	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
LZS3_k127_5565904_8	1267535.KB906767_gene3985	6.018e-41	156.0	COG0526@1|root,COG0526@2|Bacteria,3Y4UN@57723|Acidobacteria	57723|Acidobacteria	CO	PFAM Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
LZS3_k127_5565904_2	1340493.JNIF01000003_gene1978	1.322e-136	449.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_5565904_1	290397.Adeh_2523	1.255e-145	478.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YXKT@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_5565904_10	234267.Acid_5312	3.482e-30	120.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
LZS3_k127_5565904_7	1121877.JQKF01000007_gene981	7.203e-50	187.0	COG1398@1|root,COG1398@2|Bacteria,2GJJF@201174|Actinobacteria	201174|Actinobacteria	I	PFAM Fatty acid desaturase	desC	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS3_k127_5565904_4	234267.Acid_4969	3.873e-108	355.0	COG1028@1|root,COG1028@2|Bacteria,3Y3CD@57723|Acidobacteria	57723|Acidobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_5565904_0	240016.ABIZ01000001_gene3432	5.215e-217	701.0	COG0304@1|root,COG0304@2|Bacteria	2|Bacteria	I	3-oxoacyl-[acyl-carrier-protein] synthase activity	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
LZS3_k127_5565904_11	234267.Acid_4127	1.268e-24	106.0	COG0429@1|root,COG0429@2|Bacteria,3Y3MP@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_6
LZS3_k127_5566853_12	1122179.KB890431_gene4230	1.986e-31	123.0	COG0412@1|root,COG0412@2|Bacteria,4NEUX@976|Bacteroidetes,1IPA9@117747|Sphingobacteriia	976|Bacteroidetes	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
LZS3_k127_5566853_0	1499967.BAYZ01000104_gene3700	3.363e-284	894.0	COG1082@1|root,COG3291@1|root,COG1082@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2,UnbV_ASPIC,VCBS
LZS3_k127_5566853_11	1267535.KB906767_gene71	1.542e-34	134.0	COG2924@1|root,COG2924@2|Bacteria,3Y4ZS@57723|Acidobacteria	57723|Acidobacteria	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
LZS3_k127_5566853_14	1380600.AUYN01000009_gene1075	3.407e-07	59.0	COG5652@1|root,COG5652@2|Bacteria,4PP4C@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
LZS3_k127_5566853_8	234267.Acid_2124	3.41e-80	285.0	COG0531@1|root,COG0531@2|Bacteria,3Y6HV@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS3_k127_5566853_4	1340493.JNIF01000003_gene2039	1.049e-155	498.0	2E9F7@1|root,333NI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5566853_13	861299.J421_6042	1.734e-11	65.0	2EGPU@1|root,31UHV@2|Bacteria,1ZV7H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5566853_9	1340493.JNIF01000003_gene4787	1.747e-79	279.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
LZS3_k127_5566853_2	234267.Acid_6438	6.018e-218	701.0	COG1572@1|root,COG2304@1|root,COG5426@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG5426@2|Bacteria,3Y6YC@57723|Acidobacteria	57723|Acidobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
LZS3_k127_5566853_10	234267.Acid_6437	2.057e-66	242.0	COG4249@1|root,COG4249@2|Bacteria,3Y6DQ@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
LZS3_k127_5566853_3	234267.Acid_6436	7.921e-192	625.0	COG0457@1|root,COG0457@2|Bacteria,3Y6C4@57723|Acidobacteria	57723|Acidobacteria	E	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
LZS3_k127_5566853_6	234267.Acid_6435	6.939e-136	441.0	COG0714@1|root,COG0714@2|Bacteria,3Y3BH@57723|Acidobacteria	57723|Acidobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS3_k127_5566853_7	234267.Acid_6434	3.425e-100	334.0	COG1721@1|root,COG1721@2|Bacteria,3Y5XW@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS3_k127_5566853_5	234267.Acid_6433	1.112e-152	513.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
LZS3_k127_5566853_1	234267.Acid_6432	6.887e-237	778.0	COG0497@1|root,COG3266@1|root,COG0497@2|Bacteria,COG3266@2|Bacteria,3Y6KC@57723|Acidobacteria	57723|Acidobacteria	L	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5568186_3	497964.CfE428DRAFT_0984	7.969e-93	316.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_5568186_1	383372.Rcas_3628	3.832e-108	368.0	COG0399@1|root,COG0399@2|Bacteria,2G7WW@200795|Chloroflexi,37751@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_5568186_4	1463920.JOGB01000065_gene4271	2.013e-70	273.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,2GMQS@201174|Actinobacteria	201174|Actinobacteria	E	peptidase M36	-	-	-	ko:K01417	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,Peptidase_M36
LZS3_k127_5568186_6	591157.SSLG_05142	1.157e-11	79.0	COG2755@1|root,COG3534@1|root,COG2755@2|Bacteria,COG3534@2|Bacteria,2GK5H@201174|Actinobacteria	201174|Actinobacteria	E	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
LZS3_k127_5568186_7	908340.HMPREF9406_4171	5.638e-06	57.0	COG3836@1|root,COG3836@2|Bacteria,1UZZG@1239|Firmicutes,24DTX@186801|Clostridia,36JVT@31979|Clostridiaceae	186801|Clostridia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.20,4.1.2.52	ko:K01630,ko:K02510	ko00053,ko00350,ko01120,map00053,map00350,map01120	-	R01645,R01647,R02754,R03277	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
LZS3_k127_5568186_2	1340493.JNIF01000003_gene4787	2.778e-93	314.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y62R@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
LZS3_k127_5568186_5	1267535.KB906767_gene1327	8.927e-48	177.0	2F1AE@1|root,33UBD@2|Bacteria,3Y7PJ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5568186_0	1267535.KB906767_gene1026	2.812e-163	527.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_5570089_18	1267535.KB906767_gene221	3.639e-66	231.0	COG1082@1|root,COG1082@2|Bacteria,3Y65C@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_5570089_24	419947.MRA_2623A	1.223e-14	76.0	COG2002@1|root,COG2002@2|Bacteria,2HANT@201174|Actinobacteria	201174|Actinobacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5570089_26	1385521.N803_10960	1.019e-08	63.0	COG1848@1|root,COG1848@2|Bacteria,2IR37@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	PIN
LZS3_k127_5570089_19	234267.Acid_2502	1.095e-65	232.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_5570089_10	234267.Acid_5529	3.36e-142	466.0	COG1312@1|root,COG1312@2|Bacteria,3Y693@57723|Acidobacteria	57723|Acidobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
LZS3_k127_5570089_6	234267.Acid_2022	2.413e-183	583.0	COG0104@1|root,COG0104@2|Bacteria,3Y2Z9@57723|Acidobacteria	57723|Acidobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
LZS3_k127_5570089_25	525904.Tter_1427	3.163e-12	79.0	COG1716@1|root,COG1716@2|Bacteria,2NQ4X@2323|unclassified Bacteria	2|Bacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
LZS3_k127_5570089_23	909663.KI867150_gene1783	2.678e-33	146.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2MQFP@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Lysin motif	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
LZS3_k127_5570089_17	179408.Osc7112_0805	6.092e-69	246.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HBKK@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
LZS3_k127_5570089_1	1469607.KK073768_gene2203	8.428e-304	966.0	COG1020@1|root,COG3321@1|root,COG1020@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,1HIST@1161|Nostocales	1117|Cyanobacteria	Q	acyl transferase domain	-	-	-	ko:K16129	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Aminotran_3,Bac_luciferase,Condensation,KAsynt_C_assoc,Ketoacyl-synt_C,Methyltransf_12,PP-binding,ketoacyl-synt
LZS3_k127_5570089_8	56107.Cylst_1620	4.685e-167	548.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G3NP@1117|Cyanobacteria,1HIUE@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
LZS3_k127_5570089_0	306281.AJLK01000081_gene1682	0.0	1146.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
LZS3_k127_5570089_15	204669.Acid345_1181	9.93e-85	287.0	COG2930@1|root,COG2930@2|Bacteria,3Y4GG@57723|Acidobacteria,2JKH3@204432|Acidobacteriia	204432|Acidobacteriia	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
LZS3_k127_5570089_4	234267.Acid_4088	3.575e-203	663.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS3_k127_5570089_21	1340493.JNIF01000003_gene2296	2.963e-38	158.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	ko:K18106	ko00040,ko01100,map00040,map01100	M00630	R07676,R10565	RC00108	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_5570089_5	1340493.JNIF01000003_gene2295	5.547e-188	597.0	COG0160@1|root,COG0160@2|Bacteria,3Y3P2@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS3_k127_5570089_14	234267.Acid_4834	3.235e-91	313.0	COG0768@1|root,COG0768@2|Bacteria,3Y3EP@57723|Acidobacteria	57723|Acidobacteria	M	PFAM penicillin-binding protein transpeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
LZS3_k127_5570089_2	234267.Acid_7040	2.878e-247	782.0	COG0323@1|root,COG0323@2|Bacteria,3Y2T3@57723|Acidobacteria	57723|Acidobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
LZS3_k127_5570089_16	1340493.JNIF01000004_gene838	1.302e-75	265.0	COG0684@1|root,COG0684@2|Bacteria,3Y7HG@57723|Acidobacteria	57723|Acidobacteria	M	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
LZS3_k127_5570089_13	1340493.JNIF01000004_gene838	2.743e-100	335.0	COG0684@1|root,COG0684@2|Bacteria,3Y7HG@57723|Acidobacteria	57723|Acidobacteria	M	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
LZS3_k127_5570089_9	391625.PPSIR1_24429	7.856e-164	527.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,42M3J@68525|delta/epsilon subdivisions,2WJZA@28221|Deltaproteobacteria,2YZ8X@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
LZS3_k127_5570089_20	1267535.KB906767_gene2139	6.63e-52	194.0	COG0352@1|root,COG0352@2|Bacteria,3Y4Y5@57723|Acidobacteria,2JJM3@204432|Acidobacteriia	204432|Acidobacteriia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
LZS3_k127_5570089_11	1267535.KB906767_gene4528	1.516e-115	381.0	COG0078@1|root,COG0078@2|Bacteria,3Y4R3@57723|Acidobacteria,2JP1M@204432|Acidobacteriia	204432|Acidobacteriia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
LZS3_k127_5570089_3	1267535.KB906767_gene4529	8.363e-205	643.0	COG0137@1|root,COG0137@2|Bacteria,3Y4Y9@57723|Acidobacteria,2JJKA@204432|Acidobacteriia	204432|Acidobacteriia	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
LZS3_k127_5570089_7	234267.Acid_2504	7.488e-183	584.0	COG0165@1|root,COG0165@2|Bacteria,3Y36Y@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
LZS3_k127_5570089_22	1267535.KB906767_gene562	2.831e-37	149.0	COG1438@1|root,COG1438@2|Bacteria,3Y551@57723|Acidobacteria	57723|Acidobacteria	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
LZS3_k127_5570089_27	313624.NSP_3840	0.0006324	48.0	COG1598@1|root,COG1598@2|Bacteria,1GHQ1@1117|Cyanobacteria,1HPRV@1161|Nostocales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5570089_12	1267535.KB906767_gene3126	2.902e-101	344.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS3_k127_5570516_9	323261.Noc_1350	4.332e-39	153.0	2BQC7@1|root,32J7B@2|Bacteria,1RJJJ@1224|Proteobacteria,1SQUV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5570516_7	234267.Acid_7445	1.387e-46	179.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria	57723|Acidobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_5570516_13	1403819.BATR01000018_gene574	5.823e-06	58.0	COG0673@1|root,COG0673@2|Bacteria,46U48@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_5570516_6	1123023.JIAI01000007_gene1829	1.835e-49	181.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	pdxH	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
LZS3_k127_5570516_8	234267.Acid_5899	2.58e-43	177.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
LZS3_k127_5570516_12	404380.Gbem_1552	2.184e-10	73.0	COG0823@1|root,COG3794@1|root,COG4625@1|root,COG0823@2|Bacteria,COG3794@2|Bacteria,COG4625@2|Bacteria,1QU2X@1224|Proteobacteria	1224|Proteobacteria	G	outer membrane autotransporter barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Big_3_5,Calx-beta,He_PIG,TIG
LZS3_k127_5570516_0	234267.Acid_3952	0.0	1180.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
LZS3_k127_5570516_10	1499967.BAYZ01000154_gene1455	2.206e-35	147.0	COG1357@1|root,COG1357@2|Bacteria,2NPTJ@2323|unclassified Bacteria	2|Bacteria	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS3_k127_5570516_1	1267534.KB906759_gene1728	3.976e-243	764.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1164	PFOR_II,POR,POR_N,Transketolase_C
LZS3_k127_5570516_2	1267534.KB906759_gene1729	2.367e-119	391.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	2|Bacteria	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
LZS3_k127_5570516_3	1123508.JH636446_gene6317	2.879e-92	316.0	COG3618@1|root,COG3618@2|Bacteria,2IY4K@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_5570516_4	321327.CYA_0606	2.404e-89	313.0	COG0378@1|root,COG0378@2|Bacteria,1G0GT@1117|Cyanobacteria,1GYI8@1129|Synechococcus	1117|Cyanobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	iJN678.ureG	cobW
LZS3_k127_5570516_5	1499967.BAYZ01000123_gene2554	1.942e-83	289.0	COG0309@1|root,COG0309@2|Bacteria	2|Bacteria	O	Hydrogenase expression formation protein (HypE)	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
LZS3_k127_5570516_11	1463845.JOIG01000005_gene3272	1.168e-14	76.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
LZS3_k127_5591691_19	1267535.KB906767_gene1639	1.024e-31	129.0	COG4775@1|root,COG4775@2|Bacteria,3Y9FK@57723|Acidobacteria	57723|Acidobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_5591691_7	479434.Sthe_0453	1.863e-89	304.0	COG1409@1|root,COG1409@2|Bacteria,2G88X@200795|Chloroflexi,27Z25@189775|Thermomicrobia	189775|Thermomicrobia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_5591691_22	879212.DespoDRAFT_03569	1.695e-15	87.0	COG3409@1|root,COG3409@2|Bacteria,1NGZT@1224|Proteobacteria	1224|Proteobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
LZS3_k127_5591691_20	471874.PROSTU_03539	1.015e-22	102.0	2EDJ0@1|root,337EV@2|Bacteria,1N9QM@1224|Proteobacteria,1ST0P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5591691_4	518766.Rmar_2417	6.035e-131	432.0	COG3191@1|root,COG3191@2|Bacteria,4NGDT@976|Bacteroidetes,1FJRD@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
LZS3_k127_5591691_3	234267.Acid_1276	4.809e-165	526.0	COG0343@1|root,COG0343@2|Bacteria,3Y3CP@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
LZS3_k127_5591691_21	234267.Acid_1277	2.541e-21	97.0	COG1862@1|root,COG1862@2|Bacteria,3Y5GK@57723|Acidobacteria	57723|Acidobacteria	U	Preprotein translocase, YajC	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
LZS3_k127_5591691_1	1340493.JNIF01000003_gene1851	7.213e-187	599.0	COG0342@1|root,COG0342@2|Bacteria,3Y37S@57723|Acidobacteria	57723|Acidobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS3_k127_5591691_5	234267.Acid_1279	5.09e-115	383.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria	57723|Acidobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS3_k127_5591691_9	234267.Acid_1280	5.776e-86	291.0	COG0810@1|root,COG0810@2|Bacteria,3Y31T@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS3_k127_5591691_6	234267.Acid_1281	7.598e-114	371.0	COG0811@1|root,COG0811@2|Bacteria,3Y2M4@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
LZS3_k127_5591691_14	234267.Acid_1282	1.482e-51	186.0	COG0848@1|root,COG0848@2|Bacteria,3Y4TE@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS3_k127_5591691_17	234267.Acid_1283	7.279e-41	155.0	COG0848@1|root,COG0848@2|Bacteria,3Y5AP@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS3_k127_5591691_12	234267.Acid_1284	1.249e-73	256.0	COG0457@1|root,COG0457@2|Bacteria,3Y3N5@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
LZS3_k127_5591691_0	234267.Acid_1285	5.304e-302	943.0	COG0317@1|root,COG0317@2|Bacteria,3Y38Q@57723|Acidobacteria	57723|Acidobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
LZS3_k127_5591691_24	1524467.IV04_15780	8.598e-12	71.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S9VR@1236|Gammaproteobacteria,40512@613|Serratia	1236|Gammaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
LZS3_k127_5591691_2	204669.Acid345_0153	3.079e-174	563.0	COG0439@1|root,COG0439@2|Bacteria,3Y3FH@57723|Acidobacteria,2JKRD@204432|Acidobacteriia	204432|Acidobacteriia	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS3_k127_5591691_18	234267.Acid_1859	5.924e-36	143.0	COG4770@1|root,COG4770@2|Bacteria,3Y5QJ@57723|Acidobacteria	57723|Acidobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
LZS3_k127_5591691_10	1267535.KB906767_gene2417	9.13e-84	285.0	COG1484@1|root,COG1484@2|Bacteria,3Y3EK@57723|Acidobacteria,2JI9M@204432|Acidobacteriia	204432|Acidobacteriia	L	IstB-like ATP binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
LZS3_k127_5591691_11	404589.Anae109_3258	2.551e-74	255.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,42SBN@68525|delta/epsilon subdivisions,2WP4A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Rhodanese domain protein	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,Rhodanese
LZS3_k127_5591691_8	1255043.TVNIR_1705	4.517e-86	299.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS3_k127_5591691_16	1255043.TVNIR_1704	1.058e-42	159.0	COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,1S809@1236|Gammaproteobacteria,1WZQ6@135613|Chromatiales	135613|Chromatiales	P	DsrE/DsrF-like family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
LZS3_k127_5591691_13	1089550.ATTH01000002_gene84	7.939e-67	240.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
LZS3_k127_5612748_14	373994.Riv7116_4184	1.214e-23	112.0	COG0438@1|root,COG0438@2|Bacteria,1GISW@1117|Cyanobacteria,1HRDW@1161|Nostocales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
LZS3_k127_5612748_6	1267534.KB906756_gene619	2.253e-83	285.0	2DBQG@1|root,2ZADX@2|Bacteria	2|Bacteria	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_5612748_10	1267535.KB906767_gene1709	1.886e-46	175.0	COG0500@1|root,COG2226@2|Bacteria,3Y89Z@57723|Acidobacteria	57723|Acidobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_5612748_11	502025.Hoch_5782	9.463e-41	160.0	COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,42RKD@68525|delta/epsilon subdivisions,2WNAE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
LZS3_k127_5612748_7	1237149.C900_03855	4.015e-72	261.0	COG2170@1|root,COG2170@2|Bacteria,4NGA3@976|Bacteroidetes	976|Bacteroidetes	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
LZS3_k127_5612748_5	572477.Alvin_2830	1.921e-99	344.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,1RNXP@1236|Gammaproteobacteria,1WX7Y@135613|Chromatiales	135613|Chromatiales	HJ	Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,RLAN,RimK
LZS3_k127_5612748_8	382464.ABSI01000010_gene3272	1.199e-59	220.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06992	-	-	-	-	ko00000	-	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2
LZS3_k127_5612748_0	880073.Calab_3769	1.537e-286	897.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS3_k127_5612748_4	234267.Acid_5133	2.353e-101	341.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	serA5	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_5612748_12	234267.Acid_1452	5.158e-36	145.0	COG2134@1|root,COG2134@2|Bacteria,3Y7SW@57723|Acidobacteria	57723|Acidobacteria	I	cdp-diacylglycerol pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5612748_1	234267.Acid_5363	1.074e-128	421.0	COG0232@1|root,COG0232@2|Bacteria,3Y2S2@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
LZS3_k127_5612748_15	234267.Acid_5362	1.234e-23	109.0	COG2976@1|root,COG2976@2|Bacteria,3Y9AW@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
LZS3_k127_5612748_3	1340493.JNIF01000003_gene2613	4.285e-109	372.0	COG4585@1|root,COG4585@2|Bacteria,3Y59R@57723|Acidobacteria	57723|Acidobacteria	T	PFAM ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
LZS3_k127_5612748_2	1340493.JNIF01000003_gene2614	1.642e-109	357.0	COG2197@1|root,COG2197@2|Bacteria,3Y669@57723|Acidobacteria	57723|Acidobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_5612748_9	639030.JHVA01000001_gene3810	4.895e-56	199.0	COG2133@1|root,COG2133@2|Bacteria,3Y6W0@57723|Acidobacteria,2JKWW@204432|Acidobacteriia	204432|Acidobacteriia	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
LZS3_k127_5616418_0	1340493.JNIF01000004_gene234	9.652e-240	772.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
LZS3_k127_5616418_1	1340493.JNIF01000004_gene233	5.326e-183	584.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_5618482_0	266117.Rxyl_0238	1.073e-189	602.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4CPJR@84995|Rubrobacteria	84995|Rubrobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
LZS3_k127_5618482_3	234267.Acid_4515	1.459e-128	419.0	COG1131@1|root,COG1131@2|Bacteria,3Y6FZ@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_5618482_6	1382359.JIAL01000001_gene1268	4.756e-89	305.0	COG1277@1|root,COG1277@2|Bacteria,3Y6D0@57723|Acidobacteria	57723|Acidobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
LZS3_k127_5618482_4	1382359.JIAL01000001_gene1267	9.159e-112	377.0	COG3225@1|root,COG3225@2|Bacteria,3Y6WR@57723|Acidobacteria	57723|Acidobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
LZS3_k127_5618482_7	234267.Acid_4518	2.495e-80	286.0	2ANCT@1|root,31DBC@2|Bacteria,3Y69A@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
LZS3_k127_5618482_1	1340493.JNIF01000003_gene1813	1.113e-165	539.0	COG3119@1|root,COG3119@2|Bacteria,3Y3PF@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_5618482_5	234267.Acid_1287	3.417e-92	317.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS3_k127_5618482_2	234267.Acid_1807	1.251e-145	469.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Thioredoxin_7
LZS3_k127_5618482_8	234267.Acid_1806	1.114e-05	53.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IP@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS3_k127_5653614_0	1123368.AUIS01000004_gene115	2.027e-98	331.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2NDJD@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,Response_reg
LZS3_k127_5653614_1	1123242.JH636434_gene4908	3.223e-53	203.0	COG0412@1|root,COG0412@2|Bacteria,2IXM6@203682|Planctomycetes	203682|Planctomycetes	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
LZS3_k127_565910_4	1267535.KB906767_gene5074	2.142e-46	181.0	COG2193@1|root,COG2193@2|Bacteria,3Y56Z@57723|Acidobacteria,2JMWM@204432|Acidobacteriia	204432|Acidobacteriia	C	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
LZS3_k127_565910_8	443143.GM18_3649	4.455e-27	115.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
LZS3_k127_565910_5	338963.Pcar_0982	1.523e-38	151.0	COG1993@1|root,COG1993@2|Bacteria,1N0EM@1224|Proteobacteria,42TZK@68525|delta/epsilon subdivisions,2WQ2E@28221|Deltaproteobacteria,43SQ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	CBS,DUF190
LZS3_k127_565910_9	234267.Acid_1993	0.0009967	46.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB2	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
LZS3_k127_565910_2	1459636.NTE_03328	1.365e-75	260.0	COG1741@1|root,arCOG02935@2157|Archaea	2157|Archaea	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
LZS3_k127_565910_6	1340493.JNIF01000003_gene2692	3.086e-33	136.0	COG2825@1|root,COG2825@2|Bacteria,3Y8ID@57723|Acidobacteria	57723|Acidobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
LZS3_k127_565910_0	234267.Acid_7135	1.323e-133	439.0	COG0750@1|root,COG0750@2|Bacteria,3Y2KN@57723|Acidobacteria	57723|Acidobacteria	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
LZS3_k127_565910_1	234267.Acid_7136	5.844e-129	423.0	COG0743@1|root,COG0743@2|Bacteria,3Y30J@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
LZS3_k127_565910_3	756272.Plabr_4030	9.831e-59	211.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	ywlC1	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS3_k127_5660361_3	502025.Hoch_6445	2.104e-213	674.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR
LZS3_k127_5660361_17	118161.KB235922_gene5337	5.343e-20	98.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1GC8T@1117|Cyanobacteria	1117|Cyanobacteria	Q	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Lactonase
LZS3_k127_5660361_2	861299.J421_0887	4.232e-217	706.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1ZUNU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_5660361_12	234267.Acid_7677	3.266e-61	216.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
LZS3_k127_5660361_21	639030.JHVA01000001_gene2001	0.0002886	51.0	COG2823@1|root,COG2823@2|Bacteria,3Y4E1@57723|Acidobacteria,2JJ50@204432|Acidobacteriia	204432|Acidobacteriia	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5660361_11	234267.Acid_2953	4.549e-64	234.0	COG2304@1|root,COG2304@2|Bacteria,3Y7U1@57723|Acidobacteria	2|Bacteria	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	FHA,VWA,VWA_2
LZS3_k127_5660361_19	335543.Sfum_0262	2.054e-10	70.0	COG0789@1|root,COG0789@2|Bacteria,1Q2SA@1224|Proteobacteria,438DW@68525|delta/epsilon subdivisions,2WXRH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_2
LZS3_k127_5660361_18	56780.SYN_00029	5.384e-19	92.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2MRYF@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS3_k127_5660361_4	886293.Sinac_5715	3.349e-195	623.0	COG3356@1|root,COG3356@2|Bacteria,2J2EY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5660361_8	1104324.P186_1129	5.301e-106	360.0	COG2031@1|root,arCOG04315@2157|Archaea,2XRZD@28889|Crenarchaeota	28889|Crenarchaeota	I	Short chain fatty acid transporter	-	-	-	ko:K02106	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.73.1	-	-	SCFA_trans
LZS3_k127_5660361_5	234267.Acid_1085	1.973e-120	394.0	COG0123@1|root,COG0123@2|Bacteria,3Y46F@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS3_k127_5660361_7	234267.Acid_1084	2.433e-109	362.0	COG0280@1|root,COG0280@2|Bacteria,3Y6AD@57723|Acidobacteria	57723|Acidobacteria	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
LZS3_k127_5660361_10	204669.Acid345_4694	1.949e-74	261.0	COG0611@1|root,COG0611@2|Bacteria,3Y30U@57723|Acidobacteria,2JHT0@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS3_k127_5660361_9	234267.Acid_3567	2.285e-76	268.0	COG0739@1|root,COG0739@2|Bacteria,3Y3N4@57723|Acidobacteria	57723|Acidobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS3_k127_5660361_15	234267.Acid_1446	5.852e-35	148.0	COG3437@1|root,COG3437@2|Bacteria,3Y907@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
LZS3_k127_5660361_6	1121859.KB890738_gene3329	2.187e-113	381.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
LZS3_k127_5660361_0	1340493.JNIF01000003_gene3494	1.981e-235	750.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.102	ko:K06978,ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	AXE1,Big_5,LTD,Peptidase_S9,Tannase
LZS3_k127_5660361_1	471854.Dfer_2454	9.101e-218	693.0	COG2936@1|root,COG2936@2|Bacteria,4NFFB@976|Bacteroidetes,47JKV@768503|Cytophagia	976|Bacteroidetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
LZS3_k127_5660361_13	234267.Acid_7823	1.034e-58	219.0	COG2017@1|root,COG2017@2|Bacteria,3Y4YM@57723|Acidobacteria	57723|Acidobacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5660361_20	1340493.JNIF01000003_gene4251	3.647e-10	70.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	FHA,VWA,VWA_2
LZS3_k127_5660361_14	234267.Acid_2835	4.05e-48	184.0	COG1322@1|root,COG1322@2|Bacteria,3Y3JC@57723|Acidobacteria	57723|Acidobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5678361_8	1267535.KB906767_gene3483	3.973e-87	299.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_5678361_7	382464.ABSI01000010_gene3488	6.519e-91	319.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS3_k127_5678361_1	379066.GAU_3550	7.997e-125	415.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
LZS3_k127_5678361_2	639030.JHVA01000001_gene2855	2.23e-105	354.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
LZS3_k127_5678361_9	269482.Bcep1808_3375	6.002e-32	130.0	COG1439@1|root,COG1439@2|Bacteria,1N0N0@1224|Proteobacteria,2W55H@28216|Betaproteobacteria,1KC1U@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4411)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4411
LZS3_k127_5678361_3	449447.MAE_50260	3.7e-101	342.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1GAYI@1117|Cyanobacteria	1117|Cyanobacteria	K	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
LZS3_k127_5678361_0	234267.Acid_7210	1.775e-173	550.0	COG0500@1|root,COG2226@2|Bacteria,3Y6R8@57723|Acidobacteria	57723|Acidobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
LZS3_k127_5678361_10	1500897.JQNA01000002_gene1348	3.956e-24	119.0	COG1078@1|root,COG1078@2|Bacteria,1R5S2@1224|Proteobacteria	1224|Proteobacteria	S	HD superfamily	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
LZS3_k127_5678361_4	1340493.JNIF01000004_gene759	8.187e-98	328.0	COG0667@1|root,COG0667@2|Bacteria,3Y6M9@57723|Acidobacteria	57723|Acidobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_5678361_6	395961.Cyan7425_1987	6.047e-96	319.0	COG0284@1|root,COG0284@2|Bacteria,1G2ED@1117|Cyanobacteria,3KGCY@43988|Cyanothece	1117|Cyanobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
LZS3_k127_5678361_5	1121875.KB907546_gene2715	4.128e-97	329.0	COG1082@1|root,COG1082@2|Bacteria,4NIDT@976|Bacteroidetes,1I800@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_5687294_3	204669.Acid345_4105	5.345e-27	111.0	COG0776@1|root,COG0776@2|Bacteria,3Y56V@57723|Acidobacteria,2JJMF@204432|Acidobacteriia	204432|Acidobacteriia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS3_k127_5687294_1	234267.Acid_4300	7.971e-65	225.0	COG0537@1|root,COG0537@2|Bacteria,3Y4CN@57723|Acidobacteria	57723|Acidobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
LZS3_k127_5687294_5	644966.Tmar_1212	1.012e-08	63.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS3_k127_5687294_2	1126627.BAWE01000004_gene1916	2.529e-40	165.0	COG4961@1|root,COG4961@2|Bacteria,1QV5Z@1224|Proteobacteria,2TWAQ@28211|Alphaproteobacteria,3JSGE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
LZS3_k127_5687294_0	1123277.KB893172_gene951	6.763e-200	648.0	COG2133@1|root,COG3386@1|root,COG4386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,COG4386@2|Bacteria,4PNUT@976|Bacteroidetes,47YJ9@768503|Cytophagia	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS3_k127_5687294_4	1227497.C491_17454	3.127e-09	70.0	COG0737@1|root,arCOG02832@2157|Archaea,2XTTH@28890|Euryarchaeota,23TVH@183963|Halobacteria	183963|Halobacteria	F	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases	ush	-	3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
LZS3_k127_5696342_3	1265505.ATUG01000002_gene955	6.396e-31	135.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,42SGW@68525|delta/epsilon subdivisions,2WPC6@28221|Deltaproteobacteria,2MPZ5@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_5696342_4	398578.Daci_1076	2.136e-29	134.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,2VNEM@28216|Betaproteobacteria,4ABEV@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_5696342_5	1458357.BG58_01710	5.093e-28	127.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,2VNEM@28216|Betaproteobacteria,1K5AJ@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_5696342_1	1183438.GKIL_3640	0.0	1023.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1GBPU@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
LZS3_k127_5696342_2	234267.Acid_4597	4.384e-186	591.0	COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS3_k127_5696342_0	65393.PCC7424_5756	0.0	1205.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,3KJ4W@43988|Cyanothece	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,TauD,Thioesterase
LZS3_k127_5699135_8	944479.JQLX01000012_gene985	2.962e-07	58.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2M6RY@213113|Desulfurellales	28221|Deltaproteobacteria	Q	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
LZS3_k127_5699135_7	278963.ATWD01000001_gene4021	7.985e-37	148.0	2E19M@1|root,2ZCDB@2|Bacteria,3Y4DH@57723|Acidobacteria,2JJ2T@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5699135_3	1121013.P873_06340	4.428e-71	257.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1X3PM@135614|Xanthomonadales	135614|Xanthomonadales	E	acid dehydrogenase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
LZS3_k127_5699135_4	234267.Acid_2934	5.165e-55	198.0	COG3945@1|root,COG3945@2|Bacteria,3Y5T8@57723|Acidobacteria	57723|Acidobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
LZS3_k127_5699135_2	1297742.A176_05066	6.394e-99	342.0	COG4531@1|root,COG4531@2|Bacteria,1REHQ@1224|Proteobacteria,42TZ1@68525|delta/epsilon subdivisions,2WQ6N@28221|Deltaproteobacteria,2YY91@29|Myxococcales	28221|Deltaproteobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5699135_5	246197.MXAN_5554	1.968e-51	189.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS3_k127_5699135_6	483219.LILAB_35255	1.165e-46	177.0	COG2010@1|root,COG2010@2|Bacteria,1RDVX@1224|Proteobacteria,42WYA@68525|delta/epsilon subdivisions,2WT1Y@28221|Deltaproteobacteria,2Z0GX@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS3_k127_5699135_0	483219.LILAB_35260	6.297e-213	671.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2YU0I@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
LZS3_k127_5699135_1	1278073.MYSTI_06132	2.291e-99	330.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	iron-sulfur binding	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_5707786_13	3988.XP_002539122.1	1.216e-24	110.0	COG0344@1|root,2SVTS@2759|Eukaryota	2759|Eukaryota	I	Glycerol-3-phosphate acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	G3P_acyltransf
LZS3_k127_5707786_10	404589.Anae109_1214	6.029e-54	197.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,42TQ7@68525|delta/epsilon subdivisions,2WS2Q@28221|Deltaproteobacteria,2Z36A@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
LZS3_k127_5707786_1	502025.Hoch_3629	2.256e-204	650.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43957@68525|delta/epsilon subdivisions,2X4BI@28221|Deltaproteobacteria,2YYP6@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
LZS3_k127_5707786_8	404589.Anae109_1211	6.224e-79	277.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
LZS3_k127_5707786_9	290397.Adeh_2527	4.163e-59	217.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
LZS3_k127_5707786_3	1267535.KB906767_gene1183	1.225e-136	441.0	COG0451@1|root,COG0451@2|Bacteria,3Y3T4@57723|Acidobacteria,2JIDC@204432|Acidobacteriia	204432|Acidobacteriia	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
LZS3_k127_5707786_5	395961.Cyan7425_4676	4.688e-88	304.0	COG0842@1|root,COG0842@2|Bacteria,1G259@1117|Cyanobacteria	1117|Cyanobacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS3_k127_5707786_4	221288.JH992901_gene4685	6.632e-95	324.0	COG0842@1|root,COG0842@2|Bacteria,1G1MT@1117|Cyanobacteria,1JJ7B@1189|Stigonemataceae	1117|Cyanobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
LZS3_k127_5707786_0	118163.Ple7327_1671	8.005e-218	700.0	COG1131@1|root,COG1131@2|Bacteria,1G1P6@1117|Cyanobacteria,3VHUZ@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_5707786_6	1267535.KB906767_gene2095	2.773e-84	295.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	yhiI	-	-	ko:K01993,ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS3_k127_5707786_11	234267.Acid_5987	2.85e-46	186.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_5707786_2	1185876.BN8_04442	4.098e-181	577.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	2|Bacteria	M	mandelate racemase muconate lactonizing	rspA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0047929,GO:0071704,GO:1901575	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_5707786_12	1267535.KB906767_gene3216	4.991e-42	167.0	COG2823@1|root,COG2823@2|Bacteria,3Y3MJ@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS3_k127_5707786_7	1198114.AciX9_0376	4.734e-84	291.0	COG4591@1|root,COG4591@2|Bacteria,3Y3DS@57723|Acidobacteria,2JHS5@204432|Acidobacteriia	204432|Acidobacteriia	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_5710068_19	234267.Acid_7445	2.893e-19	91.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria	57723|Acidobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_5710068_6	234267.Acid_5538	3.021e-121	396.0	COG3828@1|root,COG3828@2|Bacteria,3Y61V@57723|Acidobacteria	57723|Acidobacteria	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
LZS3_k127_5710068_5	234267.Acid_3254	1.632e-127	419.0	COG4783@1|root,COG4783@2|Bacteria,3Y3GF@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_5710068_18	204669.Acid345_1584	2.641e-34	133.0	2E8MJ@1|root,32S5J@2|Bacteria,3Y53W@57723|Acidobacteria,2JNZ2@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
LZS3_k127_5710068_2	1056820.KB900663_gene3775	2.193e-176	572.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,2PPKQ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	OPT oligopeptide transporter protein	oliA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	OPT
LZS3_k127_5710068_15	1499967.BAYZ01000154_gene1455	2.864e-53	209.0	COG1357@1|root,COG1357@2|Bacteria,2NPTJ@2323|unclassified Bacteria	2|Bacteria	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
LZS3_k127_5710068_1	28072.Nos7524_1679	3.451e-197	627.0	arCOG06766@1|root,2Z87F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5710068_0	1170562.Cal6303_4456	0.0	1180.0	COG2303@1|root,COG4757@1|root,COG2303@2|Bacteria,COG4757@2|Bacteria,1G5DG@1117|Cyanobacteria,1HRGW@1161|Nostocales	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
LZS3_k127_5710068_11	1192034.CAP_7964	4.538e-72	261.0	COG3540@1|root,COG3540@2|Bacteria,1NWMQ@1224|Proteobacteria,4382N@68525|delta/epsilon subdivisions,2X3CQ@28221|Deltaproteobacteria,2YVFX@29|Myxococcales	28221|Deltaproteobacteria	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5710068_14	378806.STAUR_6820	2.119e-53	197.0	2CDDP@1|root,33XZD@2|Bacteria,1NVRR@1224|Proteobacteria,4380H@68525|delta/epsilon subdivisions,2X3AJ@28221|Deltaproteobacteria,2YV52@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5710068_17	1245469.S58_07740	9.748e-35	134.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,3K02Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
LZS3_k127_5710068_16	880072.Desac_0145	2.546e-38	149.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WRF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
LZS3_k127_5710068_13	1499967.BAYZ01000068_gene1971	1.16e-66	237.0	COG1994@1|root,COG1994@2|Bacteria,2NP89@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
LZS3_k127_5710068_23	1298593.TOL_0243	0.0001022	49.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,1SDBT@1236|Gammaproteobacteria,1XM5F@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
LZS3_k127_5710068_22	903818.KI912268_gene2009	5.064e-10	64.0	2E3CB@1|root,32YBM@2|Bacteria,3Y8J2@57723|Acidobacteria	2|Bacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
LZS3_k127_5710068_7	756272.Plabr_2749	6.109e-112	374.0	COG1520@1|root,COG1520@2|Bacteria,2IXSV@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_5710068_4	1209989.TepiRe1_1967	6.561e-148	486.0	COG4670@1|root,COG4670@2|Bacteria,1TP5H@1239|Firmicutes,247ZG@186801|Clostridia,42FS5@68295|Thermoanaerobacterales	186801|Clostridia	I	Coenzyme A transferase	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
LZS3_k127_5710068_8	234267.Acid_6664	1.845e-103	351.0	COG2271@1|root,COG2271@2|Bacteria,3Y2VG@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
LZS3_k127_5710068_3	1174528.JH992893_gene5855	2.025e-161	528.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
LZS3_k127_5710068_12	530564.Psta_3193	1.506e-67	244.0	COG4886@1|root,COG4886@2|Bacteria,2IZUK@203682|Planctomycetes	203682|Planctomycetes	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
LZS3_k127_5710068_20	204669.Acid345_1853	9.987e-16	85.0	2EBAA@1|root,335AW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
LZS3_k127_5710068_10	795666.MW7_1725	3.511e-72	266.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNBG@28216|Betaproteobacteria,1K297@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Pfam Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
LZS3_k127_5710068_9	234267.Acid_5004	7.354e-98	331.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
LZS3_k127_571569_1	1379698.RBG1_1C00001G0607	1.639e-131	442.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS3_k127_571569_6	1082933.MEA186_06086	3.02e-45	175.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1R20U@1224|Proteobacteria,2U3F2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_6
LZS3_k127_571569_7	1379698.RBG1_1C00001G0518	1.979e-33	135.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS3_k127_571569_5	1379698.RBG1_1C00001G0607	9.194e-60	217.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS3_k127_571569_4	1434929.X946_1416	5.351e-67	248.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2VZN8@28216|Betaproteobacteria,1KGFG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17
LZS3_k127_571569_8	234267.Acid_6765	4.102e-29	122.0	COG1314@1|root,COG1314@2|Bacteria,3Y56S@57723|Acidobacteria	57723|Acidobacteria	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
LZS3_k127_571569_3	234267.Acid_6502	1.709e-97	325.0	COG0149@1|root,COG0149@2|Bacteria,3Y2YS@57723|Acidobacteria	57723|Acidobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
LZS3_k127_571569_2	1340493.JNIF01000004_gene779	2.31e-123	411.0	COG1921@1|root,COG1921@2|Bacteria,3Y2SF@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
LZS3_k127_571569_10	1408444.JHYC01000003_gene646	9.344e-07	54.0	2ENCP@1|root,33G06@2|Bacteria,1P756@1224|Proteobacteria,1SU1K@1236|Gammaproteobacteria,1JF0F@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_571569_9	1260251.SPISAL_00715	1.049e-28	118.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1WYZ3@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
LZS3_k127_571569_0	234267.Acid_5711	2.853e-196	641.0	COG2319@1|root,COG2319@2|Bacteria,3Y69Q@57723|Acidobacteria	57723|Acidobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_571569_11	886293.Sinac_1517	1.681e-05	48.0	COG2010@1|root,COG2319@1|root,COG2010@2|Bacteria,COG2319@2|Bacteria,2IXWG@203682|Planctomycetes	203682|Planctomycetes	C	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
LZS3_k127_573397_3	314230.DSM3645_24005	4.701e-13	70.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_573397_0	243090.RB4667	6.512e-126	417.0	COG1520@1|root,COG1520@2|Bacteria	243090.RB4667|-	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_573397_2	1123242.JH636434_gene5600	2.715e-20	101.0	COG3618@1|root,COG3618@2|Bacteria,2IY4K@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_573397_1	1267535.KB906767_gene4416	7.659e-120	392.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria,2JI06@204432|Acidobacteriia	57723|Acidobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_11,Hexapep
LZS3_k127_5734053_13	1499967.BAYZ01000095_gene4126	3.813e-130	423.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
LZS3_k127_5734053_36	1167006.UWK_01962	9.368e-61	228.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
LZS3_k127_5734053_52	1121378.KB899742_gene3637	2.741e-05	48.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS3_k127_5734053_7	234267.Acid_3623	6.02e-201	639.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria	57723|Acidobacteria	Q	D-aminoacylase domain protein	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
LZS3_k127_5734053_30	479434.Sthe_2500	9.476e-72	250.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi,27XFS@189775|Thermomicrobia	189775|Thermomicrobia	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
LZS3_k127_5734053_45	1122939.ATUD01000012_gene3152	1.449e-23	111.0	COG1920@1|root,COG1920@2|Bacteria,2HNVD@201174|Actinobacteria,4CQ43@84995|Rubrobacteria	84995|Rubrobacteria	S	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
LZS3_k127_5734053_22	485913.Krac_0981	1.075e-93	318.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
LZS3_k127_5734053_39	1220534.B655_0507	2.923e-49	183.0	COG2085@1|root,arCOG00457@2157|Archaea,2XUD2@28890|Euryarchaeota,23PI0@183925|Methanobacteria	183925|Methanobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
LZS3_k127_5734053_33	1382356.JQMP01000001_gene1164	3.9e-68	244.0	COG0697@1|root,COG0697@2|Bacteria,2GBDJ@200795|Chloroflexi,27YYR@189775|Thermomicrobia	189775|Thermomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_5734053_16	234267.Acid_6225	2.105e-113	374.0	COG2120@1|root,COG2120@2|Bacteria,3Y7FS@57723|Acidobacteria	57723|Acidobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_5734053_0	1125863.JAFN01000001_gene663	0.0	1611.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS3_k127_5734053_14	118168.MC7420_6517	1.277e-117	394.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1H82U@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS3_k127_5734053_37	643473.KB235930_gene3513	4.102e-58	214.0	COG3386@1|root,COG3386@2|Bacteria,1G05C@1117|Cyanobacteria,1HMYE@1161|Nostocales	1117|Cyanobacteria	G	SMP-30 Gluconolaconase LRE domain protein	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
LZS3_k127_5734053_23	1267535.KB906767_gene4929	1.853e-90	312.0	28KEJ@1|root,2ZA0T@2|Bacteria,3Y6AA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5734053_43	1267535.KB906767_gene4829	3.902e-37	145.0	2FHXP@1|root,349QN@2|Bacteria,3Y8M3@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5734053_27	1340493.JNIF01000003_gene4277	3.104e-82	281.0	COG1396@1|root,COG1396@2|Bacteria,3Y5UK@57723|Acidobacteria	57723|Acidobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5734053_34	234267.Acid_7053	1.125e-63	223.0	COG0163@1|root,COG0163@2|Bacteria,3Y2S8@57723|Acidobacteria	57723|Acidobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	-	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
LZS3_k127_5734053_21	324602.Caur_0549	2.881e-96	329.0	COG2128@1|root,COG2128@2|Bacteria,2G7WP@200795|Chloroflexi,376HC@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
LZS3_k127_5734053_53	1292034.OR37_02840	8.558e-05	47.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2KEZ4@204458|Caulobacterales	204458|Caulobacterales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
LZS3_k127_5734053_15	234267.Acid_6726	5.097e-114	378.0	COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS3_k127_5734053_17	1340493.JNIF01000003_gene1663	3.296e-112	387.0	28MCK@1|root,2ZAQP@2|Bacteria,3Y41I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5734053_51	1457393.AZ09_08110	3.749e-10	65.0	COG1598@1|root,COG1598@2|Bacteria,1RIRX@1224|Proteobacteria,2U92H@28211|Alphaproteobacteria,2JTTT@204441|Rhodospirillales	204441|Rhodospirillales	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
LZS3_k127_5734053_50	1336235.JAEG01000007_gene1637	6.359e-14	76.0	COG1598@1|root,COG1598@2|Bacteria,1RIRX@1224|Proteobacteria,2U92H@28211|Alphaproteobacteria,4BEZ8@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
LZS3_k127_5734053_26	1267535.KB906767_gene5001	3.257e-86	318.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
LZS3_k127_5734053_9	234267.Acid_3577	8.891e-194	623.0	COG0249@1|root,COG0249@2|Bacteria,3Y48T@57723|Acidobacteria	57723|Acidobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
LZS3_k127_5734053_44	1340493.JNIF01000003_gene3456	6.869e-29	127.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
LZS3_k127_5734053_8	1340493.JNIF01000004_gene597	2.991e-196	641.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_5734053_24	1267535.KB906767_gene1253	6.195e-90	307.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS3_k127_5734053_3	234267.Acid_6472	8.871e-236	739.0	COG1884@1|root,COG1884@2|Bacteria,3Y2PQ@57723|Acidobacteria	57723|Acidobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS3_k127_5734053_40	665956.HMPREF1032_00931	1.151e-48	193.0	COG3119@1|root,COG3119@2|Bacteria,1TY23@1239|Firmicutes,24XZD@186801|Clostridia	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_5734053_11	1123057.P872_24845	1.467e-172	569.0	COG4772@1|root,COG4772@2|Bacteria,4NH5V@976|Bacteroidetes,47KFP@768503|Cytophagia	976|Bacteroidetes	P	PFAM TonB-dependent Receptor	fecA	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
LZS3_k127_5734053_5	861299.J421_3809	5.817e-216	685.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
LZS3_k127_5734053_29	1040989.AWZU01000023_gene4857	1.323e-72	254.0	COG1028@1|root,COG1028@2|Bacteria,1MWIJ@1224|Proteobacteria,2U290@28211|Alphaproteobacteria,3JSB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.100,1.1.1.173,1.1.1.377,1.1.1.378	ko:K00059,ko:K18337	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	M00083,M00572	R03942,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10788,R10995,R11671	RC00029,RC00066,RC00117,RC00161	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_5734053_32	1267535.KB906767_gene3264	5.113e-70	248.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
LZS3_k127_5734053_19	204669.Acid345_2220	9.429e-106	355.0	COG1131@1|root,COG1131@2|Bacteria,3Y3I9@57723|Acidobacteria,2JIPJ@204432|Acidobacteriia	204432|Acidobacteriia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_5734053_12	234267.Acid_3170	7.49e-165	532.0	COG0621@1|root,COG0621@2|Bacteria,3Y41R@57723|Acidobacteria	57723|Acidobacteria	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
LZS3_k127_5734053_46	401053.AciPR4_3696	6.714e-23	99.0	COG0828@1|root,COG0828@2|Bacteria,3Y5J9@57723|Acidobacteria,2JJWG@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
LZS3_k127_5734053_10	234267.Acid_4372	8.048e-178	567.0	COG0448@1|root,COG0448@2|Bacteria,3Y35M@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS3_k127_5734053_20	886293.Sinac_6422	4.057e-102	354.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria,2IYZX@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
LZS3_k127_5734053_18	234267.Acid_7016	8.488e-108	364.0	COG0438@1|root,COG0438@2|Bacteria,3Y58K@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_5734053_4	1340493.JNIF01000003_gene2993	2.567e-231	728.0	COG0442@1|root,COG0442@2|Bacteria,3Y329@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
LZS3_k127_5734053_2	234267.Acid_2004	9.017e-243	778.0	COG0744@1|root,COG0744@2|Bacteria,3Y42I@57723|Acidobacteria	57723|Acidobacteria	M	PFAM glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
LZS3_k127_5734053_35	1340493.JNIF01000003_gene3823	1.289e-62	226.0	COG0457@1|root,COG0457@2|Bacteria,3Y5A8@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
LZS3_k127_5734053_31	234267.Acid_5454	9.594e-71	249.0	COG0511@1|root,COG1413@1|root,COG0511@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	pcmV	-	2.3.1.12	ko:K00627,ko:K02160,ko:K07402	ko00010,ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00010,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00307,M00376	R00209,R00742,R02569	RC00004,RC00040,RC00367,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,MDMPI_C,MDMPI_N,XdhC_C,XdhC_CoxI
LZS3_k127_5734053_25	234267.Acid_7398	4.569e-88	304.0	COG0787@1|root,COG0787@2|Bacteria,3Y2U3@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
LZS3_k127_5734053_48	1382359.JIAL01000001_gene581	1.459e-15	86.0	2A1NT@1|root,30PX5@2|Bacteria,3Y4KT@57723|Acidobacteria,2JJA5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5734053_42	1267535.KB906767_gene4292	7.014e-38	149.0	COG2802@1|root,COG2802@2|Bacteria,3Y7UX@57723|Acidobacteria	57723|Acidobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LON_substr_bdg
LZS3_k127_5734053_38	234267.Acid_0776	3.879e-56	206.0	COG0300@1|root,COG0300@2|Bacteria,3Y5F6@57723|Acidobacteria	57723|Acidobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_5734053_41	1340493.JNIF01000003_gene1559	6.78e-45	168.0	COG0703@1|root,COG0703@2|Bacteria,3Y4R0@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,TMP-TENI
LZS3_k127_5734053_28	234267.Acid_2277	1.552e-76	262.0	COG1136@1|root,COG1136@2|Bacteria,3Y412@57723|Acidobacteria	57723|Acidobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
LZS3_k127_5734053_1	234267.Acid_2278	0.0	1371.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria	57723|Acidobacteria	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS3_k127_5734053_6	861299.J421_3809	2.374e-215	686.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
LZS3_k127_5734053_54	864069.MicloDRAFT_00004920	0.0001025	49.0	2AGJR@1|root,316ST@2|Bacteria,1NGZF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5734053_49	1089553.Tph_c22910	1.818e-14	86.0	COG3385@1|root,COG3385@2|Bacteria,1UKR9@1239|Firmicutes,25G1P@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
LZS3_k127_5740868_1	1254432.SCE1572_40965	4.767e-95	317.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,42MUY@68525|delta/epsilon subdivisions,2X6WF@28221|Deltaproteobacteria,2YWNJ@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M3	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
LZS3_k127_5740868_0	1267533.KB906741_gene578	9.689e-169	543.0	COG1104@1|root,COG1104@2|Bacteria,3Y3CG@57723|Acidobacteria,2JI55@204432|Acidobacteriia	204432|Acidobacteriia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS3_k127_5740868_2	65093.PCC7418_3763	1.716e-82	290.0	COG1503@1|root,COG1503@2|Bacteria,1GADA@1117|Cyanobacteria	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5740868_3	1192034.CAP_3819	8.856e-80	283.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,42QEQ@68525|delta/epsilon subdivisions,2WQEB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
LZS3_k127_5740868_5	1192034.CAP_8537	2.484e-53	196.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,42PKE@68525|delta/epsilon subdivisions,2X99A@28221|Deltaproteobacteria,2Z2QS@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
LZS3_k127_5740868_4	397948.Cmaq_0585	1.687e-54	204.0	COG0620@1|root,arCOG01876@2157|Archaea,2XPKF@28889|Crenarchaeota	28889|Crenarchaeota	E	Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
LZS3_k127_5748357_3	314285.KT71_17691	1.755e-23	104.0	COG0500@1|root,COG2226@2|Bacteria,1PF7G@1224|Proteobacteria,1TH7V@1236|Gammaproteobacteria,1JAWQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS3_k127_5748357_2	234267.Acid_5665	2.933e-58	207.0	COG0634@1|root,COG0634@2|Bacteria,3Y2FD@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
LZS3_k127_5748357_0	1280952.HJA_06147	7.934e-148	483.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,HemolysinCabind,VCBS
LZS3_k127_5748357_1	234267.Acid_3608	1.425e-79	280.0	COG0318@1|root,COG0318@2|Bacteria,3Y74C@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_5786416_4	234267.Acid_2600	8.273e-42	158.0	COG2404@1|root,COG2404@2|Bacteria,3Y98M@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5786416_0	608538.HTH_0199	7.46e-202	638.0	COG0422@1|root,COG0422@2|Bacteria,2G3RS@200783|Aquificae	200783|Aquificae	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
LZS3_k127_5786416_5	1457250.BBMO01000002_gene2994	3.234e-20	100.0	arCOG01781@1|root,arCOG01781@2157|Archaea,2XSY0@28890|Euryarchaeota,23RWZ@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	scm	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_5786416_3	234267.Acid_6710	5.008e-50	183.0	COG0782@1|root,COG0782@2|Bacteria,3Y49X@57723|Acidobacteria	57723|Acidobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
LZS3_k127_5786416_2	1267535.KB906767_gene3789	6.458e-75	259.0	COG0558@1|root,COG0558@2|Bacteria,3Y427@57723|Acidobacteria,2JID7@204432|Acidobacteriia	204432|Acidobacteriia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS3_k127_5786416_9	1536775.H70737_09100	0.0006269	52.0	COG4894@1|root,COG4894@2|Bacteria,1VUCV@1239|Firmicutes,4I6QC@91061|Bacilli,26U9X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5786416_7	1340493.JNIF01000003_gene3542	2.726e-09	63.0	2C9TJ@1|root,2ZFZD@2|Bacteria,3Y970@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5786416_8	1289387.AUKW01000006_gene3835	1.115e-06	56.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
LZS3_k127_5786416_1	240015.ACP_1233	3.786e-103	347.0	COG4974@1|root,COG4974@2|Bacteria,3Y2RA@57723|Acidobacteria,2JHWR@204432|Acidobacteriia	204432|Acidobacteriia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
LZS3_k127_5786843_6	1163398.AJJP01000169_gene1153	3.295e-88	324.0	COG4928@1|root,COG4928@2|Bacteria	2|Bacteria	G	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
LZS3_k127_5786843_15	399739.Pmen_3474	6.561e-15	83.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria,1YIE9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
LZS3_k127_5786843_1	95619.PM1_0223685	1.589e-183	606.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,1RQKR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the GcvT family	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
LZS3_k127_5786843_14	1122614.JHZF01000016_gene545	3.831e-15	83.0	COG4311@1|root,COG4311@2|Bacteria,1N8ED@1224|Proteobacteria,2UFIN@28211|Alphaproteobacteria,2PES2@252301|Oceanicola	28211|Alphaproteobacteria	E	Sarcosine oxidase, delta subunit family	soxD_2	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
LZS3_k127_5786843_0	886293.Sinac_0843	3.149e-221	692.0	COG0069@1|root,COG0069@2|Bacteria,2J28V@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the glutamate synthase family	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Glu_synthase
LZS3_k127_5786843_10	886293.Sinac_0842	1.802e-57	211.0	COG2218@1|root,COG2218@2|Bacteria,2J49X@203682|Planctomycetes	203682|Planctomycetes	C	GXGXG motif	-	-	2.1.1.21	ko:K22082	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GXGXG
LZS3_k127_5786843_8	886293.Sinac_0841	1.057e-81	282.0	COG0034@1|root,COG0034@2|Bacteria	2|Bacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	glxB	-	2.1.1.21	ko:K22081	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	GATase_6
LZS3_k127_5786843_9	221288.JH992901_gene2820	2.777e-61	215.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
LZS3_k127_5786843_2	234267.Acid_7731	1.006e-127	411.0	COG2022@1|root,COG2022@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
LZS3_k127_5786843_16	671143.DAMO_2462	0.0007066	46.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K12065,ko:K13052	-	-	-	-	ko00000,ko02044,ko03036	3.A.7.11.1	-	-	DivIC
LZS3_k127_5786843_12	234267.Acid_6359	2.022e-32	130.0	COG1324@1|root,COG1324@2|Bacteria,3Y5P7@57723|Acidobacteria	57723|Acidobacteria	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
LZS3_k127_5786843_4	234267.Acid_6345	2.605e-101	342.0	COG1533@1|root,COG1533@2|Bacteria,3Y2S5@57723|Acidobacteria	57723|Acidobacteria	L	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS3_k127_5786843_5	234267.Acid_1521	1.311e-97	332.0	2EXCM@1|root,33QP8@2|Bacteria,3Y730@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5786843_3	204669.Acid345_3224	4.084e-103	351.0	COG0006@1|root,COG0006@2|Bacteria,3Y36W@57723|Acidobacteria,2JI54@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
LZS3_k127_5786843_7	1121405.dsmv_2565	1.017e-84	298.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42P9R@68525|delta/epsilon subdivisions,2WJAD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS3_k127_5786843_11	1340493.JNIF01000003_gene3955	5.058e-43	162.0	COG2322@1|root,COG2322@2|Bacteria,3Y5H4@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
LZS3_k127_5786843_13	448385.sce1012	3.685e-25	106.0	COG2021@1|root,COG2021@2|Bacteria,1PG00@1224|Proteobacteria,439DK@68525|delta/epsilon subdivisions,2X4NG@28221|Deltaproteobacteria,2YZAN@29|Myxococcales	28221|Deltaproteobacteria	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_5797294_1	234267.Acid_4121	3.687e-257	811.0	COG4733@1|root,COG4733@2|Bacteria,3Y67A@57723|Acidobacteria	57723|Acidobacteria	S	Putative phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage-tail_3
LZS3_k127_5797294_9	234267.Acid_4120	3.413e-38	153.0	28VY7@1|root,3470P@2|Bacteria,3Y8J4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_12	234267.Acid_4119	8.777e-24	108.0	28VY7@1|root,2ZHZF@2|Bacteria,3Y97D@57723|Acidobacteria	57723|Acidobacteria	S	Conserved hypothetical protein 2217 (DUF2460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
LZS3_k127_5797294_10	927658.AJUM01000042_gene1500	1.499e-35	153.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565,SLH
LZS3_k127_5797294_15	196490.AUEZ01000004_gene3991	1.954e-12	72.0	2A6W9@1|root,30VQZ@2|Bacteria,1P4EB@1224|Proteobacteria,2UYHQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_17	234267.Acid_4118	1.046e-10	73.0	297ZP@1|root,2ZV5T@2|Bacteria,3Y972@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_13	1267535.KB906767_gene2471	5.147e-20	95.0	299A7@1|root,2ZWDD@2|Bacteria,3Y8TK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_7	234267.Acid_4115	3.485e-112	374.0	2EVZF@1|root,33PCY@2|Bacteria,3Y6QQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_14	234267.Acid_4114	3.779e-18	91.0	2CDPF@1|root,349CP@2|Bacteria,3Y8RA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_8	234267.Acid_4113	1.244e-48	186.0	2CB8V@1|root,342T5@2|Bacteria,3Y892@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_16	1267535.KB906767_gene2467	1.065e-11	71.0	2CB8U@1|root,2ZFXN@2|Bacteria,3Y96M@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_5	234267.Acid_4111	3.164e-151	482.0	2BKJ2@1|root,32F0A@2|Bacteria,3Y70Q@57723|Acidobacteria	57723|Acidobacteria	S	P22 coat protein - gene protein 5	-	-	-	-	-	-	-	-	-	-	-	-	P22_CoatProtein
LZS3_k127_5797294_11	1267535.KB906767_gene2465	7.473e-34	138.0	2F354@1|root,33VZU@2|Bacteria,3Y7X0@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_4	234267.Acid_4109	1.725e-153	507.0	2BQIP@1|root,32JEF@2|Bacteria,3Y6MF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_3	234267.Acid_4108	2.825e-163	526.0	COG1783@1|root,COG1783@2|Bacteria,3Y64R@57723|Acidobacteria	57723|Acidobacteria	S	phage Terminase large subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5797294_2	234267.Acid_5708	2.144e-232	729.0	COG4102@1|root,COG4102@2|Bacteria,3Y793@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_5797294_0	234267.Acid_5709	1.35e-296	936.0	COG5492@1|root,COG5492@2|Bacteria,3Y7DV@57723|Acidobacteria	57723|Acidobacteria	N	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt2,PSD1
LZS3_k127_5797294_6	1267535.KB906767_gene2951	3.919e-138	454.0	COG2319@1|root,COG2319@2|Bacteria,3Y5JS@57723|Acidobacteria,2JKYH@204432|Acidobacteriia	204432|Acidobacteriia	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
LZS3_k127_5801288_0	237368.SCABRO_01840	6.395e-251	793.0	COG0624@1|root,COG1181@1|root,COG0624@2|Bacteria,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
LZS3_k127_5801288_1	682795.AciX8_1432	2.999e-161	516.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_5801288_7	41431.PCC8801_0005	2.746e-87	295.0	COG2020@1|root,COG2020@2|Bacteria,1G4HN@1117|Cyanobacteria,3KGIV@43988|Cyanothece	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
LZS3_k127_5801288_8	1089550.ATTH01000001_gene2237	7.801e-46	175.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
LZS3_k127_5801288_4	344747.PM8797T_16917	1.752e-142	459.0	COG0276@1|root,COG0276@2|Bacteria,2IX75@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
LZS3_k127_5801288_9	234267.Acid_5849	7.44e-43	164.0	COG2068@1|root,COG2068@2|Bacteria	2|Bacteria	NU	MobA-Related Protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
LZS3_k127_5801288_5	234267.Acid_5850	1.845e-130	422.0	COG1975@1|root,COG1975@2|Bacteria,3Y54Y@57723|Acidobacteria	57723|Acidobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
LZS3_k127_5801288_2	234267.Acid_2440	1.156e-151	486.0	COG0604@1|root,COG0604@2|Bacteria,3Y3PP@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_5801288_6	1379698.RBG1_1C00001G0520	2.693e-104	355.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	CHASE2,GAF,GAF_2,HATPase_c_2,SpoIIE
LZS3_k127_5801288_3	1267535.KB906767_gene2761	1.106e-150	483.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria,2JIAZ@204432|Acidobacteriia	2|Bacteria	S	Radical SAM	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS3_k127_5801288_10	1382359.JIAL01000001_gene2414	3.865e-37	142.0	COG1146@1|root,COG1146@2|Bacteria,3Y59N@57723|Acidobacteria,2JJRG@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4
LZS3_k127_5801288_11	443144.GM21_0052	4.276e-26	110.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS3_k127_5808404_3	1140.Synpcc7942_0180	1.235e-36	145.0	28IEA@1|root,2Z8GC@2|Bacteria,1G3PM@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF4435)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4435
LZS3_k127_5808404_6	1267535.KB906767_gene1980	0.0004861	48.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_37
LZS3_k127_5808404_4	411684.HPDFL43_04590	2.641e-32	127.0	COG4679@1|root,COG4679@2|Bacteria,1MZ3N@1224|Proteobacteria,2UBYT@28211|Alphaproteobacteria,43PYG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
LZS3_k127_5808404_1	243090.RB2092	9.128e-74	279.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_5808404_0	926550.CLDAP_25940	1.155e-101	339.0	COG3246@1|root,COG3246@2|Bacteria,2G81V@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:Kce	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
LZS3_k127_5808404_2	543632.JOJL01000017_gene9962	2.886e-71	252.0	COG1250@1|root,COG1250@2|Bacteria,2HFZI@201174|Actinobacteria,4DJEU@85008|Micromonosporales	201174|Actinobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
LZS3_k127_5808404_5	794903.OPIT5_20450	1.394e-10	66.0	COG4409@1|root,COG4409@2|Bacteria,46ZCY@74201|Verrucomicrobia,3K99K@414999|Opitutae	414999|Opitutae	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
LZS3_k127_5809155_7	156889.Mmc1_2782	4.148e-09	57.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_5809155_3	1267535.KB906767_gene3826	3.448e-113	383.0	COG1921@1|root,COG1921@2|Bacteria,3Y6KN@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5809155_4	472759.Nhal_2724	4.564e-79	271.0	COG2324@1|root,COG2324@2|Bacteria	2|Bacteria	S	Carotenoid biosynthesis protein	cruF	-	5.5.1.19	ko:K22502	ko00906,map00906	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	Caroten_synth
LZS3_k127_5809155_2	886293.Sinac_1155	1.398e-150	491.0	COG0666@1|root,COG0666@2|Bacteria,2J1F8@203682|Planctomycetes	203682|Planctomycetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
LZS3_k127_5809155_1	886293.Sinac_1154	3.882e-199	629.0	COG2960@1|root,COG2960@2|Bacteria,2J2KP@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
LZS3_k127_5809155_0	886293.Sinac_1153	1.406e-297	935.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	CBM60,PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5,zf-C4_Topoisom
LZS3_k127_5809155_8	1121396.KB893120_gene3067	6.736e-08	56.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5809155_6	177437.HRM2_44510	5.215e-13	74.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	rve
LZS3_k127_5809155_5	709986.Deima_2348	2.348e-38	160.0	COG2199@1|root,COG3706@2|Bacteria,1WIYY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
LZS3_k127_5815888_11	1123508.JH636449_gene7410	4.594e-54	207.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999,LptC,NLPC_P60,SH3_3
LZS3_k127_5815888_10	756499.Desde_0505	1.166e-66	251.0	COG5373@1|root,COG5373@2|Bacteria,1UUGX@1239|Firmicutes,24EBQ@186801|Clostridia,26413@186807|Peptococcaceae	186801|Clostridia	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
LZS3_k127_5815888_5	234267.Acid_7284	1.287e-106	356.0	COG2152@1|root,COG2152@2|Bacteria	2|Bacteria	G	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
LZS3_k127_5815888_0	234267.Acid_6757	2.583e-194	629.0	COG0526@1|root,COG4232@1|root,COG0526@2|Bacteria,COG4232@2|Bacteria,3Y2KW@57723|Acidobacteria	57723|Acidobacteria	CO	Thioredoxin-like	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
LZS3_k127_5815888_19	309799.DICTH_1277	8.167e-10	68.0	COG3216@1|root,COG3216@2|Bacteria	2|Bacteria	M	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
LZS3_k127_5815888_16	1340493.JNIF01000003_gene3800	7.685e-32	133.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS3_k127_5815888_20	1304885.AUEY01000019_gene1161	6.092e-07	57.0	29YUB@1|root,30KQQ@2|Bacteria,1N803@1224|Proteobacteria,437DA@68525|delta/epsilon subdivisions,2WT39@28221|Deltaproteobacteria,2MMEQ@213118|Desulfobacterales	1304885.AUEY01000019_gene1161|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5815888_4	1340493.JNIF01000004_gene404	3.989e-140	458.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
LZS3_k127_5815888_1	1267535.KB906767_gene1463	1.768e-168	550.0	COG4206@1|root,COG4206@2|Bacteria,3Y3IJ@57723|Acidobacteria,2JHQY@204432|Acidobacteriia	204432|Acidobacteriia	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_5815888_12	204669.Acid345_0630	3.289e-52	202.0	COG1721@1|root,COG1721@2|Bacteria,3Y5V9@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS3_k127_5815888_8	760568.Desku_2556	2.075e-86	305.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,260D7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
LZS3_k127_5815888_13	234267.Acid_3240	6.609e-52	195.0	COG4589@1|root,COG4589@2|Bacteria,3Y59Y@57723|Acidobacteria	57723|Acidobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
LZS3_k127_5815888_9	1267534.KB906757_gene995	1.594e-79	282.0	COG1312@1|root,COG1312@2|Bacteria	2|Bacteria	G	mannonate dehydratase activity	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
LZS3_k127_5815888_6	1121904.ARBP01000021_gene3609	1.701e-88	305.0	COG0657@1|root,COG0657@2|Bacteria,4NWD5@976|Bacteroidetes	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
LZS3_k127_5815888_18	1267535.KB906767_gene4759	1.03e-12	73.0	COG1629@1|root,COG1629@2|Bacteria,3Y2N1@57723|Acidobacteria,2JIIP@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_5815888_3	1121104.AQXH01000001_gene1376	4.725e-154	506.0	COG1249@1|root,COG1249@2|Bacteria,4NGUU@976|Bacteroidetes,1IVFB@117747|Sphingobacteriia	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	merA1	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS3_k127_5815888_17	1121104.AQXH01000001_gene1377	2.524e-28	128.0	2CIUH@1|root,32S8I@2|Bacteria,4NWAC@976|Bacteroidetes,1IYW7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5815888_15	1124780.ANNU01000006_gene2903	2.699e-35	149.0	COG0398@1|root,COG0398@2|Bacteria,4NIT2@976|Bacteroidetes,47KFE@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
LZS3_k127_5815888_14	240015.ACP_1219	2.621e-44	168.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_5815888_2	682795.AciX8_2885	4.096e-160	510.0	COG1023@1|root,COG1023@2|Bacteria,3Y2ZP@57723|Acidobacteria,2JJT6@204432|Acidobacteriia	204432|Acidobacteriia	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
LZS3_k127_5815888_7	1038860.AXAP01000029_gene686	6.966e-87	297.0	COG0546@1|root,COG0546@2|Bacteria,1QEY0@1224|Proteobacteria,2U4WX@28211|Alphaproteobacteria,3JU1D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_58207_12	234267.Acid_5311	1.113e-89	303.0	28M4B@1|root,2ZAI9@2|Bacteria,3Y3NA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_58207_17	234267.Acid_3885	7.77e-52	185.0	COG1245@1|root,COG1245@2|Bacteria	2|Bacteria	C	4Fe-4S binding domain	rnfB	-	1.8.99.2	ko:K00395,ko:K02572,ko:K03616	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FeS,Fer4,Fer4_4,Fer4_7
LZS3_k127_58207_16	234267.Acid_4576	6.534e-54	198.0	COG2010@1|root,COG2010@2|Bacteria,3Y846@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_58207_1	234267.Acid_4577	1.549e-210	668.0	COG4993@1|root,COG4993@2|Bacteria,3Y696@57723|Acidobacteria	57723|Acidobacteria	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ_2
LZS3_k127_58207_28	1335757.SPICUR_07905	3.466e-21	96.0	COG2835@1|root,COG2835@2|Bacteria,1P6IM@1224|Proteobacteria,1SV7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
LZS3_k127_58207_8	234267.Acid_1259	5.373e-129	420.0	COG0761@1|root,COG0761@2|Bacteria,3Y40M@57723|Acidobacteria	57723|Acidobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB,UbiA
LZS3_k127_58207_30	886293.Sinac_2969	9.072e-14	82.0	COG0775@1|root,COG0775@2|Bacteria,2IZY2@203682|Planctomycetes	203682|Planctomycetes	F	phosphorylase	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
LZS3_k127_58207_5	234267.Acid_1263	1.402e-144	467.0	COG1063@1|root,COG1063@2|Bacteria,3Y2H8@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_58207_4	234267.Acid_1264	6.753e-147	472.0	COG1063@1|root,COG1063@2|Bacteria,3Y30Y@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Alcohol dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_58207_10	234267.Acid_1265	1.262e-103	349.0	COG1562@1|root,COG1562@2|Bacteria,3Y3ZV@57723|Acidobacteria	57723|Acidobacteria	I	PFAM Squalene phytoene synthase	-	-	-	-	-	-	-	-	-	-	-	-	SQS_PSY
LZS3_k127_58207_11	234267.Acid_1266	2.068e-93	323.0	COG1562@1|root,COG1562@2|Bacteria,3Y3YX@57723|Acidobacteria	57723|Acidobacteria	I	PFAM Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
LZS3_k127_58207_7	234267.Acid_3564	1.369e-137	451.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria,3Y3PB@57723|Acidobacteria	57723|Acidobacteria	Q	FAD dependent oxidoreductase	-	-	1.3.5.6	ko:K00514	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04798,R04800,R07511,R09656,R09658	RC01214,RC01959	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS3_k127_58207_24	264201.pc0888	7.211e-31	137.0	COG4886@1|root,COG4886@2|Bacteria,2JGIV@204428|Chlamydiae	204428|Chlamydiae	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTB,LRR_1,LRR_6
LZS3_k127_58207_18	225117.XP_009358539.1	7.483e-51	203.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37ICC@33090|Viridiplantae,3G9ZF@35493|Streptophyta,4JMQP@91835|fabids	35493|Streptophyta	S	F-box LRR-repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,LRR_6,LRR_8
LZS3_k127_58207_25	1380600.AUYN01000001_gene2880	1.922e-25	109.0	2EFIY@1|root,339BC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_58207_22	1123258.AQXZ01000019_gene3484	1.483e-31	127.0	COG3631@1|root,COG3631@2|Bacteria,2HK7T@201174|Actinobacteria,4G7ZQ@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
LZS3_k127_58207_0	1340493.JNIF01000003_gene1440	1.009e-306	950.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
LZS3_k127_58207_23	1157637.KB892091_gene5497	2.741e-31	135.0	COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria	201174|Actinobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
LZS3_k127_58207_2	234267.Acid_1018	4.27e-209	659.0	COG0312@1|root,COG0312@2|Bacteria,3Y2TY@57723|Acidobacteria	57723|Acidobacteria	H	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	CoaE,PmbA_TldD
LZS3_k127_58207_3	234267.Acid_1017	2.581e-163	525.0	COG0312@1|root,COG0312@2|Bacteria,3Y39N@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
LZS3_k127_58207_20	234267.Acid_1016	1.35e-32	132.0	2DNWY@1|root,32UJU@2|Bacteria,3Y584@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2393)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2393
LZS3_k127_58207_13	471854.Dfer_5616	9.859e-78	275.0	COG1735@1|root,COG1735@2|Bacteria,4NJYF@976|Bacteroidetes,47NZQ@768503|Cytophagia	976|Bacteroidetes	S	Phosphotriesterase family	php	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
LZS3_k127_58207_6	1267535.KB906767_gene2632	2.065e-139	460.0	COG1570@1|root,COG1570@2|Bacteria,3Y3DP@57723|Acidobacteria,2JIQN@204432|Acidobacteriia	204432|Acidobacteriia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
LZS3_k127_58207_27	234267.Acid_3522	3.565e-24	113.0	2DKN8@1|root,32UFB@2|Bacteria,3Y55I@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
LZS3_k127_58207_31	1267535.KB906767_gene3331	3.399e-08	60.0	2ERSC@1|root,33JBJ@2|Bacteria,3Y5XV@57723|Acidobacteria,2JK5S@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_58207_19	234267.Acid_3520	9.896e-35	142.0	COG1595@1|root,COG1595@2|Bacteria,3Y5BF@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_58207_14	234267.Acid_1005	7.343e-60	214.0	COG1073@1|root,COG1073@2|Bacteria,3Y5MV@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
LZS3_k127_58207_15	661478.OP10G_4092	3.226e-54	194.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2621	LacAB_rpiB
LZS3_k127_58207_26	671143.DAMO_0384	2.078e-24	106.0	2DD3Z@1|root,2ZGDH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_58207_9	1267535.KB906767_gene2749	1.441e-119	392.0	COG3620@1|root,COG3620@2|Bacteria,3Y6X6@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
LZS3_k127_58207_21	1267535.KB906767_gene1545	4.863e-32	128.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_5843554_5	1267534.KB906756_gene313	2.151e-21	106.0	COG2304@1|root,COG2304@2|Bacteria,3Y6C6@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
LZS3_k127_5843554_2	234267.Acid_2809	6.797e-87	295.0	COG0566@1|root,COG0566@2|Bacteria,3Y3XM@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
LZS3_k127_5843554_0	1267535.KB906767_gene3956	1.98e-185	586.0	COG0082@1|root,COG0082@2|Bacteria,3Y2Z8@57723|Acidobacteria,2JINW@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
LZS3_k127_5843554_1	234267.Acid_4705	8.172e-141	455.0	COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
LZS3_k127_5843554_4	755732.Fluta_3454	2.268e-27	119.0	COG3963@1|root,COG3963@2|Bacteria,4NPMV@976|Bacteroidetes,1I1YR@117743|Flavobacteriia,2PBV6@246874|Cryomorphaceae	976|Bacteroidetes	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	MTS,Methyltransf_12,Methyltransf_25,RrnaAD
LZS3_k127_5843554_3	935836.JAEL01000014_gene2018	2.533e-61	222.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,4HDII@91061|Bacilli,1ZAWY@1386|Bacillus	91061|Bacilli	S	transport system, permease component	M1-957	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
LZS3_k127_5846225_2	344747.PM8797T_00417	3.067e-115	382.0	COG2706@1|root,COG2706@2|Bacteria,2IYTU@203682|Planctomycetes	203682|Planctomycetes	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
LZS3_k127_5846225_1	204669.Acid345_2676	1.521e-161	524.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
LZS3_k127_5846225_6	1122138.AQUZ01000017_gene6597	3.234e-07	59.0	COG2931@1|root,COG2931@2|Bacteria,2I3VG@201174|Actinobacteria	201174|Actinobacteria	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,DUF3455
LZS3_k127_5846225_3	234267.Acid_3256	6.866e-55	206.0	COG2259@1|root,COG2259@2|Bacteria,3Y7PU@57723|Acidobacteria	57723|Acidobacteria	S	Doxx family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5846225_5	937777.Deipe_3584	3.039e-10	71.0	COG2137@1|root,COG2137@2|Bacteria,1WKKC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
LZS3_k127_5846225_0	234267.Acid_4756	9.916e-184	580.0	COG0013@1|root,COG0013@2|Bacteria,3Y359@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS3_k127_5855875_6	575540.Isop_0360	7.884e-85	296.0	COG1215@1|root,COG1215@2|Bacteria,2J55A@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_5855875_11	1379698.RBG1_1C00001G0993	1.594e-30	134.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
LZS3_k127_5855875_12	644968.DFW101_2110	1.394e-14	87.0	COG1807@1|root,COG1807@2|Bacteria,1NTFE@1224|Proteobacteria,42Z1W@68525|delta/epsilon subdivisions,2WTMJ@28221|Deltaproteobacteria,2M8VB@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_5855875_10	1340493.JNIF01000003_gene1911	1.556e-58	217.0	28J3W@1|root,2Z900@2|Bacteria,3Y47Q@57723|Acidobacteria	57723|Acidobacteria	S	pfam nipsnap	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
LZS3_k127_5855875_4	383372.Rcas_0496	6.829e-120	397.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
LZS3_k127_5855875_3	234267.Acid_1587	3.168e-139	453.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria	57723|Acidobacteria	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS3_k127_5855875_8	1459636.NTE_01285	4.752e-74	260.0	COG0702@1|root,arCOG03015@2157|Archaea	2157|Archaea	GM	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
LZS3_k127_5855875_13	1122963.AUHB01000011_gene1472	5.896e-06	56.0	COG0454@1|root,COG0456@2|Bacteria,1RK56@1224|Proteobacteria,2UZJE@28211|Alphaproteobacteria,36YRR@31993|Methylocystaceae	28211|Alphaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5855875_0	234267.Acid_5844	0.0	1143.0	COG0495@1|root,COG0495@2|Bacteria,3Y37K@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
LZS3_k127_5855875_7	234267.Acid_5984	3.096e-83	288.0	COG0648@1|root,COG0648@2|Bacteria,3Y35C@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
LZS3_k127_5855875_2	234267.Acid_4306	9.494e-234	731.0	COG2960@1|root,COG2960@2|Bacteria,3Y7EA@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
LZS3_k127_5855875_1	234267.Acid_4307	0.0	1050.0	COG0551@1|root,COG0551@2|Bacteria,3Y7FR@57723|Acidobacteria	57723|Acidobacteria	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
LZS3_k127_5855875_9	1173021.ALWA01000037_gene3499	4.115e-65	231.0	COG2890@1|root,COG2890@2|Bacteria,1G51W@1117|Cyanobacteria	1117|Cyanobacteria	J	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS3_k127_5855875_5	1541065.JRFE01000010_gene4343	1.806e-104	371.0	COG3291@1|root,COG3828@1|root,COG3291@2|Bacteria,COG3828@2|Bacteria,1GHAI@1117|Cyanobacteria,3VMJ1@52604|Pleurocapsales	1117|Cyanobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
LZS3_k127_5855875_14	1254432.SCE1572_08085	0.0006809	53.0	COG3250@1|root,COG3509@1|root,COG3250@2|Bacteria,COG3509@2|Bacteria,1R16M@1224|Proteobacteria	1224|Proteobacteria	Q	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
LZS3_k127_5872498_10	713586.KB900536_gene1937	1.877e-53	191.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1WWC9@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
LZS3_k127_5872498_8	1541065.JRFE01000024_gene811	3.307e-72	258.0	COG0834@1|root,COG0834@2|Bacteria,1G36J@1117|Cyanobacteria,3VIEX@52604|Pleurocapsales	1117|Cyanobacteria	ET	Ligand-gated ion channel	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	Ion_trans_2,Lig_chan,SBP_bac_3
LZS3_k127_5872498_6	1123242.JH636434_gene3868	7.174e-99	341.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	1123242.JH636434_gene3868|-	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5872498_12	1121378.KB899706_gene1495	2.164e-43	162.0	COG0831@1|root,COG0832@1|root,COG0831@2|Bacteria,COG0832@2|Bacteria	2|Bacteria	E	Belongs to the urease beta subunit family	ureB	GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016787,GO:0016810,GO:0016811,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575	3.5.1.5	ko:K01427,ko:K01428,ko:K01429,ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	iECH74115_1262.ECH74115_1321,iECH74115_1262.ECH74115_1322,iECO103_1326.ECO103_3797,iECO103_1326.ECO103_3798,iECO111_1330.ECO111_1227,iECO111_1330.ECO111_1228,iECO26_1355.ECO26_1280,iECSP_1301.ECSP_1249,iECSP_1301.ECSP_1250,iECs_1301.ECs1322,iECs_1301.ECs1323,iUMNK88_1353.UMNK88_1199,iUMNK88_1353.UMNK88_1200,iZ_1308.Z1143,iZ_1308.Z1144,iZ_1308.Z1582,iZ_1308.Z1583	Urease_beta,Urease_gamma
LZS3_k127_5872498_11	638303.Thal_0721	1.378e-43	161.0	COG0832@1|root,COG0832@2|Bacteria	2|Bacteria	E	Belongs to the urease beta subunit family	ureB	GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0019627,GO:0034641,GO:0042221,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
LZS3_k127_5872498_0	321327.CYA_0603	1.558e-293	908.0	COG0804@1|root,COG0804@2|Bacteria,1G12D@1117|Cyanobacteria,1GZ2M@1129|Synechococcus	1117|Cyanobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
LZS3_k127_5872498_15	1173026.Glo7428_0524	2.749e-23	112.0	COG4122@1|root,COG4122@2|Bacteria,1G2Y6@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM O-methyltransferase, family 3	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
LZS3_k127_5872498_5	1380355.JNIJ01000102_gene3019	7.477e-113	374.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3K3JQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
LZS3_k127_5872498_7	530564.Psta_3944	4.331e-77	271.0	COG1858@1|root,COG1858@2|Bacteria,2IY7G@203682|Planctomycetes	203682|Planctomycetes	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS3_k127_5872498_1	1267535.KB906767_gene3825	3.181e-221	724.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_5872498_3	234267.Acid_7856	2.309e-173	558.0	COG0305@1|root,COG0305@2|Bacteria,3Y335@57723|Acidobacteria	57723|Acidobacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
LZS3_k127_5872498_9	234267.Acid_5084	9.695e-72	249.0	COG0744@1|root,COG0744@2|Bacteria,3Y48X@57723|Acidobacteria	57723|Acidobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
LZS3_k127_5872498_4	1340493.JNIF01000004_gene75	7.288e-158	506.0	COG0686@1|root,COG0686@2|Bacteria,3Y3Y9@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
LZS3_k127_5872498_13	768671.ThimaDRAFT_4684	9.317e-40	158.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,1S3RM@1236|Gammaproteobacteria,1WYEW@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5872498_2	497964.CfE428DRAFT_1242	1.993e-179	572.0	COG0823@1|root,COG0823@2|Bacteria,46SJJ@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5872498_17	644966.Tmar_1212	1.167e-11	72.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS3_k127_5872498_16	1267533.KB906738_gene2052	2.899e-15	82.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,TadE
LZS3_k127_5872498_14	1282360.ABAC460_03495	4.267e-38	160.0	COG4655@1|root,COG4655@2|Bacteria,1RGJG@1224|Proteobacteria,2U32U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
LZS3_k127_5905395_3	234267.Acid_6283	2.631e-115	393.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,3Y3AX@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_7
LZS3_k127_5905395_6	234267.Acid_6282	1.841e-86	291.0	COG0745@1|root,COG0745@2|Bacteria,3Y38C@57723|Acidobacteria	57723|Acidobacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483,ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_5905395_4	497964.CfE428DRAFT_3577	2.467e-112	375.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S9
LZS3_k127_5905395_0	518766.Rmar_0089	0.0	1188.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1FIP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_5905395_2	234267.Acid_4606	3.787e-117	401.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,3Y2MP@57723|Acidobacteria	57723|Acidobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
LZS3_k127_5905395_7	234267.Acid_2446	6.401e-68	243.0	COG0329@1|root,COG0329@2|Bacteria,3Y8R8@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
LZS3_k127_5905395_5	502025.Hoch_3248	1.682e-88	312.0	COG0204@1|root,COG0236@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
LZS3_k127_5905395_1	1395571.TMS3_0104735	1.056e-208	686.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyltransferase,Aminotran_1_2,NAD_binding_4,PP-binding,Thioesterase
LZS3_k127_5967247_1	234267.Acid_3588	7.028e-84	290.0	COG1611@1|root,COG1611@2|Bacteria,3Y2MR@57723|Acidobacteria	57723|Acidobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
LZS3_k127_5967247_2	1267535.KB906767_gene216	6.318e-64	235.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
LZS3_k127_5967247_0	1122137.AQXF01000001_gene2997	6.27e-157	512.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_603646_4	661478.OP10G_4550	6.755e-29	121.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
LZS3_k127_603646_2	1267534.KB906755_gene4336	9.299e-42	163.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
LZS3_k127_603646_5	1032480.MLP_35720	2.065e-19	95.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria,4DS8M@85009|Propionibacteriales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
LZS3_k127_603646_6	1267535.KB906767_gene3656	1.803e-08	58.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6C0@57723|Acidobacteria	57723|Acidobacteria	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
LZS3_k127_603646_1	240015.ACP_1739	8.528e-123	405.0	COG0809@1|root,COG0809@2|Bacteria,3Y336@57723|Acidobacteria,2JI3K@204432|Acidobacteriia	204432|Acidobacteriia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
LZS3_k127_603646_0	1198452.Jab_1c25830	0.0	1306.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,473K1@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Linear gramicidin synthase subunit	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
LZS3_k127_603646_3	742740.HMPREF9474_04451	1.122e-30	134.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,21Y63@1506553|Lachnoclostridium	186801|Clostridia	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
LZS3_k127_6080664_2	886293.Sinac_6095	1.893e-173	557.0	COG1073@1|root,COG1073@2|Bacteria,2IYEI@203682|Planctomycetes	203682|Planctomycetes	Q	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
LZS3_k127_6080664_11	234267.Acid_3899	3.331e-32	131.0	COG1959@1|root,COG1959@2|Bacteria,3Y8ZE@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS3_k127_6080664_3	1379270.AUXF01000004_gene3094	4.495e-167	543.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
LZS3_k127_6080664_7	1191523.MROS_1971	7.241e-66	232.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS3_k127_6080664_4	234267.Acid_7028	2.217e-138	454.0	COG0154@1|root,COG0154@2|Bacteria	2|Bacteria	J	amidase activity	gatA3	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS3_k127_6080664_0	234267.Acid_3687	1.599e-302	946.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
LZS3_k127_6080664_5	748247.AZKH_1671	1.376e-126	416.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TIGRFAM efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
LZS3_k127_6080664_1	56780.SYN_00284	1.646e-269	850.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,42PQC@68525|delta/epsilon subdivisions,2WJ8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_6080664_6	396588.Tgr7_1479	6.04e-107	351.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria,1WXTU@135613|Chromatiales	135613|Chromatiales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_6080664_8	237368.SCABRO_01444	4.078e-40	156.0	2A4CF@1|root,30SY3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
LZS3_k127_6080664_12	1046627.BZARG_8	8.728e-26	117.0	2EW6R@1|root,33PJP@2|Bacteria,4P0EV@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6080664_9	1227457.C451_03909	8.086e-40	158.0	arCOG06802@1|root,arCOG06802@2157|Archaea,2XVYT@28890|Euryarchaeota,23TZE@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6080664_10	1340493.JNIF01000003_gene2576	1.378e-34	152.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF11,VCBS
LZS3_k127_6080664_13	443143.GM18_2399	1.447e-16	87.0	2AVTU@1|root,31MME@2|Bacteria,1NQ7V@1224|Proteobacteria,42XCN@68525|delta/epsilon subdivisions,2WTFJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6142554_42	204669.Acid345_2506	4.707e-28	130.0	COG2304@1|root,COG2304@2|Bacteria,3Y2IE@57723|Acidobacteria,2JI1J@204432|Acidobacteriia	204432|Acidobacteriia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
LZS3_k127_6142554_1	215803.DB30_4199	0.0	1107.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria,2YWJW@29|Myxococcales	28221|Deltaproteobacteria	P	Cytochrome C and Quinol oxidase polypeptide I	norZ	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
LZS3_k127_6142554_39	1123023.JIAI01000032_gene4146	5.418e-31	128.0	29J5I@1|root,3062Y@2|Bacteria,2I9N8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6142554_43	234267.Acid_6606	1.395e-23	105.0	2BXJ9@1|root,2ZNPM@2|Bacteria,3Y966@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6142554_23	1382304.JNIL01000001_gene3204	9.48e-80	270.0	COG2041@1|root,COG2041@2|Bacteria,1V1P9@1239|Firmicutes,4HFQC@91061|Bacilli,278B0@186823|Alicyclobacillaceae	91061|Bacilli	S	Oxidoreductase molybdopterin binding domain	yuiH	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
LZS3_k127_6142554_38	234267.Acid_3372	4.511e-32	129.0	COG1547@1|root,COG1547@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
LZS3_k127_6142554_46	518766.Rmar_0549	1.52e-06	50.0	COG5450@1|root,COG5450@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
LZS3_k127_6142554_4	1100720.ALKN01000035_gene1001	1.442e-186	597.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
LZS3_k127_6142554_0	671143.DAMO_0621	0.0	1332.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
LZS3_k127_6142554_22	1340493.JNIF01000003_gene2685	6.588e-82	282.0	COG1475@1|root,COG1475@2|Bacteria,3Y40Y@57723|Acidobacteria	57723|Acidobacteria	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
LZS3_k127_6142554_19	1382359.JIAL01000001_gene1244	1.466e-96	322.0	COG1192@1|root,COG1192@2|Bacteria,3Y2Y2@57723|Acidobacteria,2JI26@204432|Acidobacteriia	204432|Acidobacteriia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS3_k127_6142554_41	1382359.JIAL01000001_gene1245	1.944e-28	122.0	COG0357@1|root,COG0357@2|Bacteria,3Y4W7@57723|Acidobacteria,2JJG7@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
LZS3_k127_6142554_3	204669.Acid345_0080	4.521e-264	827.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
LZS3_k127_6142554_6	648996.Theam_0942	1.206e-141	461.0	COG0151@1|root,COG0151@2|Bacteria,2G3J3@200783|Aquificae	200783|Aquificae	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
LZS3_k127_6142554_9	234267.Acid_1518	1.531e-133	433.0	COG0673@1|root,COG0673@2|Bacteria,3Y74B@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_6142554_13	243090.RB7879	1.065e-115	391.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
LZS3_k127_6142554_10	234267.Acid_1026	6.113e-129	432.0	COG2027@1|root,COG2027@2|Bacteria,3Y3WF@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
LZS3_k127_6142554_5	234267.Acid_2458	3.98e-146	468.0	COG0113@1|root,COG0113@2|Bacteria,3Y2VK@57723|Acidobacteria	57723|Acidobacteria	H	PFAM delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
LZS3_k127_6142554_18	1267535.KB906767_gene4089	9.328e-101	336.0	COG0217@1|root,COG0217@2|Bacteria,3Y2UW@57723|Acidobacteria,2JIJW@204432|Acidobacteriia	204432|Acidobacteriia	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
LZS3_k127_6142554_29	234267.Acid_5949	4.948e-55	198.0	COG0817@1|root,COG0817@2|Bacteria,3Y5FH@57723|Acidobacteria	57723|Acidobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
LZS3_k127_6142554_27	234267.Acid_6708	1.944e-65	235.0	COG0294@1|root,COG0294@2|Bacteria,3Y4JJ@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
LZS3_k127_6142554_20	1267535.KB906767_gene222	1.115e-94	322.0	COG4948@1|root,COG4948@2|Bacteria,3Y2QQ@57723|Acidobacteria,2JITG@204432|Acidobacteriia	2|Bacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
LZS3_k127_6142554_28	1267535.KB906767_gene4236	3.553e-57	209.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS3_k127_6142554_36	1094508.Tsac_2628	7.354e-36	145.0	COG0398@1|root,COG0398@2|Bacteria,1V3DJ@1239|Firmicutes,24G6T@186801|Clostridia,42G3B@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
LZS3_k127_6142554_44	204669.Acid345_0871	2.512e-21	107.0	COG3058@1|root,COG3058@2|Bacteria,3Y87B@57723|Acidobacteria	57723|Acidobacteria	O	protein involved in formate dehydrogenase formation	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
LZS3_k127_6142554_31	234267.Acid_0835	5.776e-51	189.0	COG2864@1|root,COG2864@2|Bacteria,3Y884@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome b/b6/petB	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
LZS3_k127_6142554_14	234267.Acid_0836	7.806e-111	365.0	COG0437@1|root,COG0437@2|Bacteria,3Y65I@57723|Acidobacteria	57723|Acidobacteria	C	Formate dehydrogenase N, transmembrane	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Form-deh_trans
LZS3_k127_6142554_2	393305.YE4135	6.303e-282	887.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,1RN6N@1236|Gammaproteobacteria,41F3J@629|Yersinia	1236|Gammaproteobacteria	C	formate dehydrogenase	fdoG	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:1902494	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	iECW_1372.ECW_m4203,iWFL_1372.ECW_m4203,iYL1228.KPN_04190	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_6142554_26	234267.Acid_0838	1.407e-67	237.0	COG0243@1|root,COG0243@2|Bacteria,3Y7US@57723|Acidobacteria	57723|Acidobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
LZS3_k127_6142554_30	1267535.KB906767_gene1813	4.882e-52	198.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria,2JKP5@204432|Acidobacteriia	204432|Acidobacteriia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
LZS3_k127_6142554_17	398511.BpOF4_07190	4.201e-102	348.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,4H9T7@91061|Bacilli,1ZCSU@1386|Bacillus	91061|Bacilli	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
LZS3_k127_6142554_33	234267.Acid_3615	9.925e-43	161.0	2E6AT@1|root,330YQ@2|Bacteria,3Y5M7@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6142554_12	344747.PM8797T_25751	7.517e-125	407.0	COG0388@1|root,COG0388@2|Bacteria,2IWZ6@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
LZS3_k127_6142554_8	234267.Acid_1043	2.237e-136	439.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
LZS3_k127_6142554_24	234267.Acid_3177	8.563e-78	268.0	COG4137@1|root,COG4137@2|Bacteria,3Y9FX@57723|Acidobacteria	57723|Acidobacteria	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
LZS3_k127_6142554_7	234267.Acid_3178	5.731e-140	460.0	COG0373@1|root,COG0373@2|Bacteria,3Y3DQ@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS3_k127_6142554_21	234267.Acid_3179	2.202e-87	299.0	COG0181@1|root,COG0181@2|Bacteria,3Y3RY@57723|Acidobacteria	57723|Acidobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
LZS3_k127_6142554_15	234267.Acid_7368	7.537e-109	361.0	COG2220@1|root,COG2220@2|Bacteria,3Y2TV@57723|Acidobacteria	57723|Acidobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS3_k127_6142554_25	234267.Acid_7179	8.039e-69	239.0	COG2077@1|root,COG2077@2|Bacteria,3Y5DK@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
LZS3_k127_6142554_11	234267.Acid_2474	2.202e-127	420.0	COG0624@1|root,COG0624@2|Bacteria,3Y2XS@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS3_k127_6142554_16	234267.Acid_4252	1.196e-107	360.0	COG0613@1|root,COG0613@2|Bacteria,3Y2US@57723|Acidobacteria	57723|Acidobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6142554_40	1173028.ANKO01000158_gene4530	1.394e-30	128.0	2EWB0@1|root,33PPQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6142554_37	344747.PM8797T_05625	1.519e-33	140.0	2E6E7@1|root,3311P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6142554_45	1232410.KI421421_gene3262	2.519e-10	65.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria,43SJH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS3_k127_6142554_35	234267.Acid_0722	2.53e-38	148.0	COG4818@1|root,COG4818@2|Bacteria,3Y8T8@57723|Acidobacteria	57723|Acidobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6142554_32	1340493.JNIF01000003_gene4236	7.937e-51	190.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
LZS3_k127_6150244_3	234267.Acid_5816	1.069e-217	683.0	COG0339@1|root,COG0339@2|Bacteria,3Y3U9@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase	-	-	3.4.15.5,3.4.24.70	ko:K01284,ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
LZS3_k127_6150244_4	234267.Acid_4068	2.667e-178	564.0	COG0473@1|root,COG0473@2|Bacteria,3Y38Z@57723|Acidobacteria	57723|Acidobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS3_k127_6150244_5	1340493.JNIF01000003_gene4560	1.334e-165	529.0	COG0119@1|root,COG0119@2|Bacteria,3Y2WT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
LZS3_k127_6150244_9	234267.Acid_4066	4.059e-114	375.0	COG0583@1|root,COG0583@2|Bacteria,3Y31P@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS3_k127_6150244_10	237368.SCABRO_03425	2.178e-65	234.0	COG0463@1|root,COG0463@2|Bacteria,2IZV0@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6150244_1	234267.Acid_6547	1.289e-301	949.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
LZS3_k127_6150244_2	234267.Acid_6548	3.37e-221	694.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_6150244_11	1210884.HG799466_gene12574	4.172e-45	168.0	2EDAV@1|root,33776@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6150244_7	204669.Acid345_1385	1.902e-130	419.0	COG0479@1|root,COG0479@2|Bacteria,3Y70A@57723|Acidobacteria,2JM7N@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
LZS3_k127_6150244_0	1267533.KB906735_gene4585	5.626e-311	962.0	COG1053@1|root,COG1053@2|Bacteria,3Y6IU@57723|Acidobacteria,2JKAD@204432|Acidobacteriia	204432|Acidobacteriia	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS3_k127_6150244_8	1210884.HG799466_gene12570	3.366e-125	405.0	2CEY7@1|root,2Z8CG@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6150244_12	1408415.JHXL01000003_gene1060	7.04e-40	163.0	COG2871@1|root,COG2871@2|Bacteria,3WU3S@544448|Tenericutes	544448|Tenericutes	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
LZS3_k127_6150244_14	234267.Acid_4414	1.643e-19	92.0	COG1872@1|root,COG1872@2|Bacteria,3Y5S4@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
LZS3_k127_6150244_6	234267.Acid_4415	1.543e-149	482.0	COG0006@1|root,COG0006@2|Bacteria,3Y3I4@57723|Acidobacteria	57723|Acidobacteria	E	PFAM peptidase M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
LZS3_k127_6150244_13	269799.Gmet_3073	1.844e-35	143.0	COG3222@1|root,COG3222@2|Bacteria,1RHCP@1224|Proteobacteria,43B9I@68525|delta/epsilon subdivisions,2X6NN@28221|Deltaproteobacteria,43SK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Guanylyl transferase CofC like	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
LZS3_k127_6150244_15	264732.Moth_1685	7.168e-12	70.0	COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,248A1@186801|Clostridia,42EQ9@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Substrate-binding region of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
LZS3_k127_6192847_8	1123057.P872_13075	6.73e-37	148.0	COG4122@1|root,COG4122@2|Bacteria,4PBU1@976|Bacteroidetes,47WBZ@768503|Cytophagia	976|Bacteroidetes	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
LZS3_k127_6192847_4	243231.GSU0928	5.426e-86	304.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WNZ3@28221|Deltaproteobacteria,43SW2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_6192847_1	1379698.RBG1_1C00001G0712	9.218e-108	370.0	COG0612@1|root,COG0612@2|Bacteria,2NQPM@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_6192847_9	765912.Thimo_0407	3.311e-10	63.0	COG3742@1|root,COG3742@2|Bacteria,1N937@1224|Proteobacteria,1SBDZ@1236|Gammaproteobacteria,1WYY1@135613|Chromatiales	135613|Chromatiales	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K19686	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
LZS3_k127_6192847_10	1125863.JAFN01000001_gene1985	2.848e-05	47.0	COG4423@1|root,COG4423@2|Bacteria	2|Bacteria	S	positive regulation of growth	vapB30	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	PSK_trans_fac
LZS3_k127_6192847_3	886293.Sinac_0431	1.064e-96	331.0	COG2133@1|root,COG2133@2|Bacteria,2J52Q@203682|Planctomycetes	203682|Planctomycetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_6192847_5	886293.Sinac_0496	1.762e-48	176.0	COG1742@1|root,COG1742@2|Bacteria,2J0XN@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterised BCR, YnfA/UPF0060 family	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
LZS3_k127_6192847_0	309807.SRU_2272	1.211e-129	432.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,4NGF6@976|Bacteroidetes,1FJIA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
LZS3_k127_6192847_2	309807.SRU_2273	1.231e-104	360.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,Na_H_Exchanger,TrkA_N
LZS3_k127_6192847_6	886293.Sinac_7114	1.969e-48	190.0	COG3119@1|root,COG3119@2|Bacteria,2IXUK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
LZS3_k127_6192847_7	1089547.KB913013_gene1008	9.068e-44	175.0	COG4948@1|root,COG4948@2|Bacteria,4NP0T@976|Bacteroidetes,47XKQ@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_6201067_3	234267.Acid_7441	8.949e-53	193.0	COG1216@1|root,COG1216@2|Bacteria,3Y7JI@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
LZS3_k127_6201067_1	234267.Acid_7442	4.648e-150	481.0	COG1216@1|root,COG1216@2|Bacteria,3Y7CJ@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6201067_2	234267.Acid_7443	1.985e-131	438.0	COG0438@1|root,COG0438@2|Bacteria,3Y6A8@57723|Acidobacteria	57723|Acidobacteria	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glyco_trans_1_4
LZS3_k127_6201067_5	1449347.JQLN01000007_gene1150	1.829e-41	167.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,2M1F5@2063|Kitasatospora	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
LZS3_k127_6201067_0	243231.GSU2675	4.275e-262	826.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,42P5Q@68525|delta/epsilon subdivisions,2WKD3@28221|Deltaproteobacteria,43TC9@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
LZS3_k127_6201067_4	234267.Acid_3885	1.244e-50	190.0	COG1245@1|root,COG1245@2|Bacteria	2|Bacteria	C	4Fe-4S binding domain	rnfB	-	1.8.99.2	ko:K00395,ko:K02572,ko:K03616	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FeS,Fer4,Fer4_4,Fer4_7
LZS3_k127_6239854_18	240015.ACP_0450	6.021e-19	89.0	COG2801@1|root,COG2801@2|Bacteria,3Y6NP@57723|Acidobacteria,2JNG9@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6239854_5	292415.Tbd_1051	2.654e-112	379.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VKYV@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS3_k127_6239854_20	1340493.JNIF01000004_gene904	5.288e-10	68.0	2EMD6@1|root,33F24@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6239854_13	1000565.METUNv1_01086	2.714e-66	234.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2WH0E@28216|Betaproteobacteria,2KZYC@206389|Rhodocyclales	28216|Betaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
LZS3_k127_6239854_17	1463855.JOHV01000001_gene1700	1.407e-21	107.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
LZS3_k127_6239854_15	1038860.AXAP01000032_gene4402	3.204e-55	202.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria,3JV2Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	BPD_transp_1
LZS3_k127_6239854_0	290397.Adeh_2253	1.476e-221	704.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales	28221|Deltaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
LZS3_k127_6239854_11	1121405.dsmv_1693	6.291e-75	257.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,2MMB5@213118|Desulfobacterales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
LZS3_k127_6239854_3	56107.Cylst_1620	3.07e-156	515.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G3NP@1117|Cyanobacteria,1HIUE@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
LZS3_k127_6239854_2	1267535.KB906767_gene5243	3.443e-175	560.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_6239854_16	1382356.JQMP01000001_gene940	1.279e-52	198.0	COG3718@1|root,COG3718@2|Bacteria,2G708@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Myo-inositol catabolism IolB domain protein	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
LZS3_k127_6239854_8	234267.Acid_5289	1.663e-91	306.0	COG0800@1|root,COG0800@2|Bacteria,3Y4HZ@57723|Acidobacteria	57723|Acidobacteria	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
LZS3_k127_6239854_10	234267.Acid_2356	2.373e-76	268.0	COG0859@1|root,COG0859@2|Bacteria,3Y616@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_6239854_1	234267.Acid_2355	3.511e-212	678.0	COG1132@1|root,COG1132@2|Bacteria,3Y2Y9@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
LZS3_k127_6239854_14	234267.Acid_2354	2.85e-64	235.0	COG1561@1|root,COG1561@2|Bacteria,3Y2HQ@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
LZS3_k127_6239854_12	1267535.KB906767_gene1436	2.6e-69	240.0	COG0194@1|root,COG0194@2|Bacteria,3Y2JW@57723|Acidobacteria,2JJ0I@204432|Acidobacteriia	204432|Acidobacteriia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
LZS3_k127_6239854_19	234267.Acid_2352	2.592e-14	76.0	COG1758@1|root,COG1758@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
LZS3_k127_6239854_4	1267535.KB906767_gene1438	7.462e-138	452.0	COG0452@1|root,COG0452@2|Bacteria,3Y2QJ@57723|Acidobacteria,2JIK5@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
LZS3_k127_6239854_7	1267535.KB906767_gene4168	1.202e-95	320.0	COG1573@1|root,COG1573@2|Bacteria,3Y43G@57723|Acidobacteria,2JJ46@204432|Acidobacteriia	204432|Acidobacteriia	L	TIGRFAM Phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS3_k127_6239854_9	1123242.JH636434_gene4022	6.255e-81	275.0	COG2738@1|root,COG2738@2|Bacteria,2IZDM@203682|Planctomycetes	203682|Planctomycetes	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
LZS3_k127_6239854_6	1382356.JQMP01000001_gene964	2.497e-101	346.0	COG4948@1|root,COG4948@2|Bacteria,2G69R@200795|Chloroflexi,27YY3@189775|Thermomicrobia	189775|Thermomicrobia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_6244681_10	1267535.KB906767_gene3869	1.388e-10	65.0	COG3637@1|root,COG3637@2|Bacteria,3Y783@57723|Acidobacteria	57723|Acidobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
LZS3_k127_6244681_9	1382356.JQMP01000001_gene797	2.571e-24	108.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
LZS3_k127_6244681_7	1121920.AUAU01000008_gene1620	2.016e-42	167.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0328	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_6244681_0	1121920.AUAU01000008_gene1619	0.0	1825.0	COG5013@1|root,COG5013@2|Bacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	iSBO_1134.SBO_1842,iUMN146_1321.UM146_09685	Molybdopterin,Molydop_binding,Nitr_red_alph_N
LZS3_k127_6244681_2	1121920.AUAU01000008_gene1618	9.278e-232	725.0	COG1140@1|root,COG1140@2|Bacteria	2|Bacteria	C	nitrate reductase beta subunit	narH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057	1.7.5.1	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	iAF987.Gmet_1021,iEcE24377_1341.EcE24377A_1376,iEcolC_1368.EcolC_2189	Fer4_11,Nitr_red_bet_C
LZS3_k127_6244681_8	1121920.AUAU01000008_gene1617	5.39e-28	122.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K17052	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
LZS3_k127_6244681_5	1121920.AUAU01000008_gene1616	1.95e-57	208.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	narI	GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204	1.7.5.1	ko:K00370,ko:K00374,ko:K02575	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00615,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.1.8,5.A.3.1	-	iEC042_1314.EC042_1594,iECABU_c1320.ECABU_c17020,iECUMN_1333.ECUMN_1718,iNJ661.Rv1164,iSF_1195.SF1230,ic_1306.c1897	Nitrate_red_gam
LZS3_k127_6244681_3	1121920.AUAU01000008_gene1622	2.788e-197	627.0	COG2223@1|root,COG2223@2|Bacteria,3Y68U@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Major Facilitator Superfamily	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
LZS3_k127_6244681_4	1049564.TevJSym_ag00810	3.785e-194	620.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,1RMUK@1236|Gammaproteobacteria,1J96M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	nitrate nitrite transporter	narK	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
LZS3_k127_6244681_6	1348583.ATLH01000029_gene1340	2.894e-56	204.0	COG4654@1|root,COG4654@2|Bacteria,4PMBX@976|Bacteroidetes,1IJR5@117743|Flavobacteriia,1F803@104264|Cellulophaga	976|Bacteroidetes	C	PFAM Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C7
LZS3_k127_6244681_1	1121920.AUAU01000008_gene1614	4.307e-295	937.0	COG0437@1|root,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria	2|Bacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molydop_binding
LZS3_k127_6265470_0	1174528.JH992898_gene1851	2.207e-201	641.0	COG3540@1|root,COG3540@2|Bacteria,1G0C9@1117|Cyanobacteria,1JKIQ@1189|Stigonemataceae	1117|Cyanobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
LZS3_k127_6265470_3	240015.ACP_2764	7.875e-05	48.0	COG4980@1|root,COG4980@2|Bacteria,3Y5HP@57723|Acidobacteria,2JJWE@204432|Acidobacteriia	204432|Acidobacteriia	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS3_k127_6265470_2	234267.Acid_7033	9.475e-26	116.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
LZS3_k127_6265470_1	1313301.AUGC01000004_gene2344	8.533e-138	473.0	COG1629@1|root,COG1629@2|Bacteria,4PKRK@976|Bacteroidetes	976|Bacteroidetes	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
LZS3_k127_6278863_9	1340493.JNIF01000003_gene2268	1.774e-54	203.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_6278863_2	1267535.KB906767_gene5001	6.237e-285	895.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
LZS3_k127_6278863_10	1340493.JNIF01000003_gene2519	2.108e-45	179.0	COG0457@1|root,COG0457@2|Bacteria,3Y7UM@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS3_k127_6278863_0	1267535.KB906767_gene5002	0.0	1193.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_6278863_1	1267535.KB906767_gene5002	0.0	1183.0	COG1629@1|root,COG4771@2|Bacteria,3Y6ZH@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_6278863_3	234267.Acid_2483	1.056e-196	620.0	COG0172@1|root,COG0172@2|Bacteria,3Y2UD@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
LZS3_k127_6278863_8	1121472.AQWN01000007_gene1144	9.48e-81	291.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_6278863_6	234267.Acid_5208	2.873e-103	346.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,3Y3HP@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM glutamate formiminotransferase	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
LZS3_k127_6278863_5	1267535.KB906767_gene769	5.438e-127	423.0	COG1109@1|root,COG1109@2|Bacteria,3Y36F@57723|Acidobacteria,2JHU9@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS3_k127_6278863_11	673860.AciM339_0328	8.689e-12	77.0	COG0535@1|root,arCOG00938@2157|Archaea,2XZ9M@28890|Euryarchaeota,3F34T@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Radical_SAM,SPASM
LZS3_k127_6278863_7	1137269.AZWL01000005_gene2155	3.874e-90	309.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
LZS3_k127_6278863_4	234267.Acid_0052	7.038e-174	559.0	COG0527@1|root,COG0527@2|Bacteria,3Y62M@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,Homoserine_dh,NAD_binding_3
LZS3_k127_6307563_1	1340493.JNIF01000004_gene371	3.905e-60	235.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
LZS3_k127_6307563_0	639030.JHVA01000001_gene95	3.704e-71	254.0	COG1312@1|root,COG1312@2|Bacteria,3Y6UB@57723|Acidobacteria	57723|Acidobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
LZS3_k127_6307563_2	344747.PM8797T_00417	2.045e-08	55.0	COG2706@1|root,COG2706@2|Bacteria,2IYTU@203682|Planctomycetes	203682|Planctomycetes	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
LZS3_k127_6323815_3	1125863.JAFN01000001_gene3383	9.836e-10	59.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
LZS3_k127_6323815_2	234267.Acid_6705	2.427e-81	273.0	COG1259@1|root,COG1259@2|Bacteria,3Y4QD@57723|Acidobacteria	57723|Acidobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
LZS3_k127_6323815_0	234267.Acid_6704	1.712e-191	612.0	COG0621@1|root,COG0621@2|Bacteria,3Y2GT@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
LZS3_k127_6323815_1	471854.Dfer_3350	2.29e-103	351.0	COG3964@1|root,COG3964@2|Bacteria,4NI4W@976|Bacteroidetes,47MS7@768503|Cytophagia	976|Bacteroidetes	S	PFAM amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_635713_19	583345.Mmol_0999	3.072e-18	87.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,2VTXT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
LZS3_k127_635713_8	234267.Acid_0027	2.29e-87	301.0	COG1082@1|root,COG1082@2|Bacteria,3Y6EB@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
LZS3_k127_635713_11	1173024.KI912149_gene6319	9.175e-71	245.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	ppaX_1	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS3_k127_635713_2	234267.Acid_5623	2.733e-147	481.0	COG4948@1|root,COG4948@2|Bacteria,3Y6CG@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_635713_1	1340493.JNIF01000003_gene3950	9.124e-157	510.0	COG0471@1|root,COG0471@2|Bacteria,3Y6TC@57723|Acidobacteria	57723|Acidobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
LZS3_k127_635713_10	42256.RradSPS_1723	9.696e-75	269.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
LZS3_k127_635713_5	448385.sce7110	1.561e-136	439.0	COG0454@1|root,COG0456@2|Bacteria,1PWDA@1224|Proteobacteria,43586@68525|delta/epsilon subdivisions,2WZJ8@28221|Deltaproteobacteria,2Z296@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_635713_20	1250232.JQNJ01000001_gene751	1.62e-11	69.0	COG0662@1|root,COG3837@1|root,COG0662@2|Bacteria,COG3837@2|Bacteria,4NHX8@976|Bacteroidetes	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_635713_9	1210884.HG799463_gene9554	9.942e-84	285.0	COG2120@1|root,COG2120@2|Bacteria,2IYPC@203682|Planctomycetes	203682|Planctomycetes	S	LmbE homologs	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_635713_12	1267535.KB906767_gene4064	9.131e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,3Y4CH@57723|Acidobacteria,2JJ6R@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
LZS3_k127_635713_17	204669.Acid345_4526	2.139e-34	145.0	COG1413@1|root,COG5662@1|root,COG1413@2|Bacteria,COG5662@2|Bacteria,3Y2TB@57723|Acidobacteria,2JHKS@204432|Acidobacteriia	204432|Acidobacteriia	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,zf-HC2
LZS3_k127_635713_15	234267.Acid_5722	2.073e-42	171.0	COG3595@1|root,COG3595@2|Bacteria,3Y8P5@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_635713_14	234267.Acid_5723	1.998e-48	185.0	COG0265@1|root,COG0265@2|Bacteria,3Y4AJ@57723|Acidobacteria	57723|Acidobacteria	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
LZS3_k127_635713_13	234267.Acid_6754	8.382e-54	207.0	29UCR@1|root,30FP6@2|Bacteria,3Y4J8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_635713_6	1340493.JNIF01000003_gene2136	6.01e-95	319.0	COG1028@1|root,COG1028@2|Bacteria,3Y2YB@57723|Acidobacteria	57723|Acidobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_635713_0	1267535.KB906767_gene2727	4.786e-262	816.0	COG0459@1|root,COG0459@2|Bacteria,3Y37I@57723|Acidobacteria,2JIV1@204432|Acidobacteriia	204432|Acidobacteriia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS3_k127_635713_16	1267535.KB906767_gene2728	1.686e-37	143.0	COG0234@1|root,COG0234@2|Bacteria,3Y4VQ@57723|Acidobacteria	57723|Acidobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS3_k127_635713_18	380749.HY04AAS1_0735	1.046e-18	91.0	COG0071@1|root,COG0071@2|Bacteria,2G4AZ@200783|Aquificae	200783|Aquificae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS3_k127_635713_3	1267535.KB906767_gene2157	3.864e-146	482.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
LZS3_k127_635713_4	1045855.DSC_13360	6.694e-146	482.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RRY3@1236|Gammaproteobacteria,1XBYN@135614|Xanthomonadales	135614|Xanthomonadales	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_635713_7	234267.Acid_3483	1.86e-91	319.0	COG0457@1|root,COG0457@2|Bacteria,3Y2IK@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8,UnbV_ASPIC,VCBS
LZS3_k127_6402094_10	1123489.AUAN01000022_gene40	8.6e-10	66.0	2ERMT@1|root,33J79@2|Bacteria,1VKZE@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6402094_6	517722.AEUE01000010_gene626	1.585e-23	109.0	2C6BD@1|root,2ZZIY@2|Bacteria,1NWJY@1224|Proteobacteria,2USK5@28211|Alphaproteobacteria,2KAE8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6402094_2	234267.Acid_4782	8.852e-105	353.0	COG0265@1|root,COG0265@2|Bacteria,3Y3HE@57723|Acidobacteria	57723|Acidobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_6402094_5	234267.Acid_4781	4.1e-63	222.0	COG0237@1|root,COG0237@2|Bacteria,3Y4R2@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
LZS3_k127_6402094_1	204669.Acid345_4424	5.857e-125	407.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JIT2@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
LZS3_k127_6402094_0	1267535.KB906767_gene451	8.254e-136	437.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	cysA2	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
LZS3_k127_6402094_3	234267.Acid_7116	2.112e-78	267.0	COG0009@1|root,COG0009@2|Bacteria,3Y43Z@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the SUA5 family	-	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
LZS3_k127_6402094_4	1267535.KB906767_gene1558	2.951e-68	243.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,3Y3YD@57723|Acidobacteria,2JIG8@204432|Acidobacteriia	204432|Acidobacteriia	E	homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
LZS3_k127_641_6	1448389.BAVQ01000006_gene3258	9.182e-20	89.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria	201174|Actinobacteria	KLT	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS3_k127_641_2	886377.Murru_2671	1.542e-109	361.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
LZS3_k127_641_0	551789.ATVJ01000002_gene2689	7.6e-140	466.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VF3C@28211|Alphaproteobacteria,43WX5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
LZS3_k127_641_4	234267.Acid_0376	1.85e-82	288.0	COG0454@1|root,COG0456@2|Bacteria,3Y3VJ@57723|Acidobacteria	57723|Acidobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_641_5	292564.Cyagr_2511	1.188e-39	157.0	COG0398@1|root,COG0398@2|Bacteria,1G3R9@1117|Cyanobacteria,22TBM@167375|Cyanobium	1117|Cyanobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
LZS3_k127_641_7	234267.Acid_0485	6.277e-13	76.0	COG0745@1|root,COG0745@2|Bacteria	234267.Acid_0485|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_641_1	234267.Acid_1438	8.675e-119	398.0	COG1807@1|root,COG1807@2|Bacteria,3Y2K3@57723|Acidobacteria	57723|Acidobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_641_3	234267.Acid_0596	2.734e-95	322.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
LZS3_k127_641_8	1265505.ATUG01000001_gene3238	0.0001857	44.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
LZS3_k127_6483325_5	234267.Acid_7757	8.034e-24	104.0	COG1430@1|root,COG1430@2|Bacteria,3Y5J5@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
LZS3_k127_6483325_3	1340493.JNIF01000003_gene2288	2.864e-27	115.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_6483325_1	234267.Acid_4451	5.021e-139	452.0	COG0673@1|root,COG0673@2|Bacteria,3Y71T@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_6483325_0	234267.Acid_7425	1.745e-170	548.0	COG0766@1|root,COG0766@2|Bacteria,3Y2IC@57723|Acidobacteria	57723|Acidobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
LZS3_k127_6483325_2	1340493.JNIF01000004_gene237	3.463e-46	181.0	2EHBQ@1|root,33B3J@2|Bacteria,3Y7KU@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
LZS3_k127_6483325_4	1192034.CAP_5903	2.979e-24	114.0	2DNQQ@1|root,32YKT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
LZS3_k127_6582375_2	1380393.JHVP01000004_gene276	1.025e-81	280.0	COG0604@1|root,COG0604@2|Bacteria,2GK7Y@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_6582375_0	234267.Acid_3201	5.335e-170	549.0	COG2755@1|root,COG2755@2|Bacteria,3Y2P4@57723|Acidobacteria	57723|Acidobacteria	E	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
LZS3_k127_6582375_6	309807.SRU_1410	4.365e-07	57.0	291YZ@1|root,2ZPIG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6582375_3	1340493.JNIF01000003_gene1333	9.539e-31	137.0	COG4963@1|root,COG4963@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
LZS3_k127_6582375_1	1340493.JNIF01000003_gene2539	3.436e-117	385.0	COG2041@1|root,COG2041@2|Bacteria,3Y2X4@57723|Acidobacteria	2|Bacteria	S	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
LZS3_k127_6582375_4	1267534.KB906754_gene2999	1.975e-17	89.0	COG0454@1|root,COG0456@2|Bacteria,3Y5KS@57723|Acidobacteria,2JJY0@204432|Acidobacteriia	204432|Acidobacteriia	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
LZS3_k127_6582375_5	1267535.KB906767_gene2205	5.49e-09	62.0	2ETRB@1|root,33M8W@2|Bacteria,3Y5ZS@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
LZS3_k127_6586961_5	344747.PM8797T_20763	7.949e-118	405.0	COG1331@1|root,COG1331@2|Bacteria,2IXCB@203682|Planctomycetes	203682|Planctomycetes	O	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
LZS3_k127_6586961_1	886293.Sinac_0608	7.853e-184	625.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NB-ARC,cNMP_binding
LZS3_k127_6586961_6	1267535.KB906767_gene3454	1.354e-113	378.0	COG4299@1|root,COG4299@2|Bacteria,3Y3Q4@57723|Acidobacteria	2|Bacteria	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
LZS3_k127_6586961_10	234267.Acid_5619	1.133e-51	186.0	COG0780@1|root,COG0780@2|Bacteria,3Y4ND@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
LZS3_k127_6586961_8	234267.Acid_4341	2.976e-70	252.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888,ko:K20948	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_88
LZS3_k127_6586961_9	1278073.MYSTI_07636	1.014e-55	201.0	COG3386@1|root,COG3386@2|Bacteria,1NFEJ@1224|Proteobacteria,43BX0@68525|delta/epsilon subdivisions,2X77S@28221|Deltaproteobacteria,2YVY8@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6586961_15	1077972.ARGLB_047_00760	9.697e-05	55.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria	201174|Actinobacteria	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_6586961_4	234267.Acid_5906	3.047e-124	406.0	COG0451@1|root,COG0451@2|Bacteria,3Y3ZG@57723|Acidobacteria	57723|Acidobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS3_k127_6586961_12	1340493.JNIF01000003_gene3800	2.506e-34	142.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS3_k127_6586961_2	234267.Acid_3614	3.07e-179	565.0	COG1060@1|root,COG1060@2|Bacteria,3Y2IA@57723|Acidobacteria	57723|Acidobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
LZS3_k127_6586961_7	234267.Acid_6764	4.567e-79	274.0	COG1427@1|root,COG1427@2|Bacteria,3Y3PU@57723|Acidobacteria	57723|Acidobacteria	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
LZS3_k127_6586961_3	234267.Acid_2400	7.01e-140	456.0	COG0322@1|root,COG0758@1|root,COG0322@2|Bacteria,COG0758@2|Bacteria,3Y42M@57723|Acidobacteria	57723|Acidobacteria	LU	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
LZS3_k127_6586961_0	1340493.JNIF01000003_gene1955	0.0	1071.0	COG0550@1|root,COG0550@2|Bacteria,3Y343@57723|Acidobacteria	57723|Acidobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
LZS3_k127_6586961_14	411467.BACCAP_04464	1.255e-08	62.0	2EPJ6@1|root,33H5U@2|Bacteria	2|Bacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6600653_38	1123389.ATXJ01000032_gene1671	0.0008684	44.0	COG4118@1|root,COG4118@2|Bacteria,1WKUE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
LZS3_k127_6600653_17	1054860.KB913030_gene325	2.357e-115	380.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria	201174|Actinobacteria	E	ornithine cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
LZS3_k127_6600653_18	234267.Acid_7935	2.576e-115	379.0	COG0825@1|root,COG0825@2|Bacteria,3Y34D@57723|Acidobacteria	57723|Acidobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
LZS3_k127_6600653_0	234267.Acid_0012	0.0	1550.0	COG0587@1|root,COG0587@2|Bacteria,3Y2TS@57723|Acidobacteria	57723|Acidobacteria	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
LZS3_k127_6600653_6	1185876.BN8_00442	9.736e-195	621.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47JC1@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_6600653_32	671143.DAMO_2130	1.415e-43	164.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	sscB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
LZS3_k127_6600653_22	1157490.EL26_17490	2.108e-92	320.0	COG0667@1|root,COG0667@2|Bacteria,1V53W@1239|Firmicutes,4HTG5@91061|Bacilli	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_6600653_3	1267535.KB906767_gene3394	3.028e-249	781.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria,2JIK1@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
LZS3_k127_6600653_35	1121405.dsmv_0797	4.694e-25	113.0	COG0484@1|root,COG0484@2|Bacteria,1RHHJ@1224|Proteobacteria,42SMN@68525|delta/epsilon subdivisions,2WPJN@28221|Deltaproteobacteria,2MNCE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
LZS3_k127_6600653_5	234267.Acid_5065	7.706e-243	772.0	COG1674@1|root,COG1674@2|Bacteria,3Y3CJ@57723|Acidobacteria	57723|Acidobacteria	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
LZS3_k127_6600653_26	1340493.JNIF01000003_gene2346	4.13e-81	280.0	COG1968@1|root,COG1968@2|Bacteria,3Y6B6@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
LZS3_k127_6600653_9	234267.Acid_5147	3.236e-161	518.0	COG2768@1|root,COG2768@2|Bacteria,3Y61G@57723|Acidobacteria	57723|Acidobacteria	C	binding domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6600653_25	383372.Rcas_3343	5.315e-83	285.0	COG2084@1|root,COG2084@2|Bacteria,2G6B3@200795|Chloroflexi,376B1@32061|Chloroflexia	32061|Chloroflexia	I	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
LZS3_k127_6600653_7	1123248.KB893325_gene1154	6.655e-191	619.0	COG4993@1|root,COG4993@2|Bacteria,4NFK0@976|Bacteroidetes,1IQUR@117747|Sphingobacteriia	2|Bacteria	C	Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
LZS3_k127_6600653_21	489825.LYNGBM3L_16970	2.794e-95	317.0	COG1225@1|root,COG1225@2|Bacteria,1G0JC@1117|Cyanobacteria,1H7GR@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_6600653_12	234267.Acid_7048	3.714e-142	459.0	COG0332@1|root,COG0332@2|Bacteria,3Y2Z5@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS3_k127_6600653_24	497964.CfE428DRAFT_0572	8.125e-88	303.0	COG3488@1|root,COG3488@2|Bacteria,46T3U@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
LZS3_k127_6600653_37	1217718.ALOU01000021_gene2445	3.653e-13	74.0	COG1622@1|root,COG1622@2|Bacteria,1NEC9@1224|Proteobacteria,2VWA0@28216|Betaproteobacteria,1K8PX@119060|Burkholderiaceae	28216|Betaproteobacteria	C	cytochrome C oxidase	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1
LZS3_k127_6600653_28	1121011.AUCB01000004_gene2825	7.196e-66	242.0	COG1730@1|root,COG1730@2|Bacteria,4NHZT@976|Bacteroidetes,1HZM3@117743|Flavobacteriia,23GBX@178469|Arenibacter	976|Bacteroidetes	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
LZS3_k127_6600653_2	234267.Acid_6644	3.568e-266	834.0	COG0322@1|root,COG0322@2|Bacteria,3Y2Y7@57723|Acidobacteria	57723|Acidobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
LZS3_k127_6600653_1	234267.Acid_3731	0.0	1096.0	2EXAB@1|root,33QKZ@2|Bacteria,3Y6WS@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6600653_16	1340493.JNIF01000004_gene551	3.838e-120	398.0	COG2304@1|root,COG2304@2|Bacteria,3Y6RY@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
LZS3_k127_6600653_31	1144319.PMI16_00693	3.792e-50	183.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2VQFV@28216|Betaproteobacteria,474FZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Acyl dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
LZS3_k127_6600653_11	756272.Plabr_0323	5.748e-146	470.0	COG1082@1|root,COG1082@2|Bacteria,2IXXS@203682|Planctomycetes	203682|Planctomycetes	G	PFAM AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
LZS3_k127_6600653_20	234267.Acid_0451	6.798e-99	340.0	COG0277@1|root,COG0277@2|Bacteria,3Y6TT@57723|Acidobacteria	57723|Acidobacteria	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
LZS3_k127_6600653_33	234267.Acid_6444	6.722e-39	157.0	2F776@1|root,33ZNH@2|Bacteria,3Y8A6@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6600653_23	330214.NIDE1125	5.138e-90	316.0	COG0301@1|root,COG0301@2|Bacteria	2|Bacteria	H	tRNA thio-modification	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
LZS3_k127_6600653_10	234267.Acid_4413	1.946e-157	506.0	COG1134@1|root,COG1134@2|Bacteria,3Y72D@57723|Acidobacteria	57723|Acidobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
LZS3_k127_6600653_14	1121937.AUHJ01000003_gene3210	5.002e-134	441.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,1RY6X@1236|Gammaproteobacteria,469JX@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Malonyl-CoA decarboxylase N-terminal domain	-	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
LZS3_k127_6600653_13	761193.Runsl_0206	4.83e-134	444.0	COG2133@1|root,COG2133@2|Bacteria,4NI97@976|Bacteroidetes,47M2X@768503|Cytophagia	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_6600653_19	1121448.DGI_0438	2.926e-104	350.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QGX@68525|delta/epsilon subdivisions,2WJPU@28221|Deltaproteobacteria,2M8JN@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6600653_34	555793.WSK_1483	2.507e-27	119.0	COG1403@1|root,COG1403@2|Bacteria,1REGI@1224|Proteobacteria,2U8AZ@28211|Alphaproteobacteria,2K9WA@204457|Sphingomonadales	204457|Sphingomonadales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6600653_15	234267.Acid_0301	2.014e-126	414.0	COG0123@1|root,COG0123@2|Bacteria,3Y5CR@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS3_k127_6600653_30	234267.Acid_1414	2.32e-52	199.0	COG2064@1|root,COG2064@2|Bacteria,3Y4FI@57723|Acidobacteria	2|Bacteria	NU	type II secretion system	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS3_k127_6600653_29	1340493.JNIF01000003_gene1287	5.247e-62	226.0	COG4965@1|root,COG4965@2|Bacteria,3Y4RR@57723|Acidobacteria	57723|Acidobacteria	U	type II secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
LZS3_k127_6600653_8	234267.Acid_1412	3.51e-165	530.0	COG4962@1|root,COG4962@2|Bacteria,3Y360@57723|Acidobacteria	57723|Acidobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
LZS3_k127_6600653_36	1121456.ATVA01000014_gene764	2.736e-23	110.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,42S07@68525|delta/epsilon subdivisions,2WNR0@28221|Deltaproteobacteria,2M87M@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	TIGRFAM Flp pilus assembly protein CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ChapFlgA,RcpC,SAF
LZS3_k127_6600653_4	1267535.KB906767_gene2631	7.576e-247	772.0	COG0174@1|root,COG0174@2|Bacteria,3Y2P8@57723|Acidobacteria,2JHXX@204432|Acidobacteriia	204432|Acidobacteriia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
LZS3_k127_6600653_27	234267.Acid_1189	6.623e-73	267.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_6601030_3	234267.Acid_6881	5.905e-41	166.0	COG1361@1|root,COG3534@1|root,COG4625@1|root,COG1361@2|Bacteria,COG3534@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	2|Bacteria	M	PKD domain containing protein	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,DUF4347,Glyco_hydro_43,He_PIG,P_proprotein,Peptidase_S8,TIG
LZS3_k127_6601030_4	234267.Acid_0422	1.782e-34	141.0	292F3@1|root,2ZPZC@2|Bacteria,3Y90G@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6601030_2	234267.Acid_4660	9.217e-44	166.0	COG0250@1|root,COG0250@2|Bacteria,3Y83Z@57723|Acidobacteria	57723|Acidobacteria	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
LZS3_k127_6601030_0	1267535.KB906767_gene2207	3.516e-80	280.0	COG1596@1|root,COG1596@2|Bacteria,3Y57H@57723|Acidobacteria,2JJNS@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
LZS3_k127_6601030_1	429009.Adeg_0700	1.855e-73	256.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS3_k127_6601030_6	688269.Theth_1656	8.743e-05	55.0	COG1470@1|root,COG1470@2|Bacteria,2GCQ8@200918|Thermotogae	200918|Thermotogae	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
LZS3_k127_662683_1	314278.NB231_00260	1.285e-142	463.0	KOG2165@1|root,2Z911@2|Bacteria,1N8JM@1224|Proteobacteria,1RR9Z@1236|Gammaproteobacteria,1WWIT@135613|Chromatiales	135613|Chromatiales	S	ubiquitin protein ligase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_662683_0	472759.Nhal_3586	0.0	1082.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1X0IX@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
LZS3_k127_662683_5	1340493.JNIF01000003_gene2793	6.992e-23	103.0	COG2930@1|root,COG2930@2|Bacteria	2|Bacteria	S	regulation of ruffle assembly	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
LZS3_k127_662683_3	439235.Dalk_1318	7.456e-32	128.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,43BHF@68525|delta/epsilon subdivisions,2WQUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS3_k127_662683_2	760568.Desku_1126	4.585e-41	166.0	COG1475@1|root,COG4725@1|root,COG1475@2|Bacteria,COG4725@2|Bacteria,1TT7N@1239|Firmicutes,24D10@186801|Clostridia	186801|Clostridia	L	ParB-like nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
LZS3_k127_662683_6	348780.NP_0052A	4.914e-19	97.0	COG0476@1|root,arCOG01676@2157|Archaea,2XTYV@28890|Euryarchaeota,23TM2@183963|Halobacteria	183963|Halobacteria	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	ubaA	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
LZS3_k127_662683_4	65093.PCC7418_3045	4.019e-28	117.0	COG2337@1|root,COG2337@2|Bacteria,1G80Y@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM PemK-like protein	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
LZS3_k127_6634176_2	1267535.KB906767_gene265	3.067e-170	548.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	hscA	-	-	-	-	-	-	-	-	-	-	-	HSP70,RNase_Zc3h12a
LZS3_k127_6634176_8	1267535.KB906767_gene874	8.927e-79	271.0	COG3375@1|root,COG3375@2|Bacteria,3Y41E@57723|Acidobacteria,2JI86@204432|Acidobacteriia	204432|Acidobacteriia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6634176_3	1267535.KB906767_gene1686	5.78e-160	518.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
LZS3_k127_6634176_4	1121904.ARBP01000013_gene373	4.861e-124	417.0	COG2730@1|root,COG2730@2|Bacteria,4P1NI@976|Bacteroidetes,47TT8@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
LZS3_k127_6634176_12	644966.Tmar_1212	1.591e-11	71.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS3_k127_6634176_14	867903.ThesuDRAFT_00034	4.959e-08	61.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
LZS3_k127_6634176_13	243090.RB1156	1.053e-08	67.0	COG4961@1|root,COG4961@2|Bacteria,2IXIS@203682|Planctomycetes	203682|Planctomycetes	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
LZS3_k127_6634176_11	1267533.KB906738_gene2053	4.81e-36	153.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	Tad
LZS3_k127_6634176_10	886293.Sinac_0868	1.883e-39	152.0	COG5507@1|root,COG5507@2|Bacteria,2J071@203682|Planctomycetes	203682|Planctomycetes	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
LZS3_k127_6634176_6	234267.Acid_1454	2.075e-92	314.0	COG1651@1|root,COG1651@2|Bacteria,3Y2G9@57723|Acidobacteria	57723|Acidobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DsbC_N,Thioredoxin_4
LZS3_k127_6634176_0	204669.Acid345_3483	2.52e-218	693.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,3Y46R@57723|Acidobacteria,2JICT@204432|Acidobacteriia	204432|Acidobacteriia	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
LZS3_k127_6634176_1	1267535.KB906767_gene693	4.265e-214	685.0	COG0308@1|root,COG0308@2|Bacteria,3Y2XM@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
LZS3_k127_6634176_9	1116472.MGMO_79c00070	2.456e-78	271.0	COG3193@1|root,COG3193@2|Bacteria,1R215@1224|Proteobacteria,1S4R1@1236|Gammaproteobacteria,1XF9H@135618|Methylococcales	135618|Methylococcales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
LZS3_k127_6634176_5	314230.DSM3645_24005	2.229e-96	331.0	COG1520@1|root,COG1520@2|Bacteria,2IYEA@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_6634176_7	1379698.RBG1_1C00001G0608	6.564e-84	299.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
LZS3_k127_6639480_23	639030.JHVA01000001_gene118	8.19e-32	133.0	COG1268@1|root,COG1268@2|Bacteria,3Y5K4@57723|Acidobacteria,2JJWF@204432|Acidobacteriia	204432|Acidobacteriia	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
LZS3_k127_6639480_16	937777.Deipe_2722	3.135e-61	230.0	COG1404@1|root,COG1404@2|Bacteria,1WKW6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	S53, subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS3_k127_6639480_22	525903.Taci_1499	2.418e-34	140.0	COG2105@1|root,COG2105@2|Bacteria,3TCD7@508458|Synergistetes	508458|Synergistetes	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
LZS3_k127_6639480_9	401053.AciPR4_1374	7.039e-104	350.0	COG0535@1|root,COG0535@2|Bacteria,3Y3TY@57723|Acidobacteria,2JHZQ@204432|Acidobacteriia	204432|Acidobacteriia	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS3_k127_6639480_15	497964.CfE428DRAFT_5266	3.069e-63	233.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_6639480_18	330214.NIDE0745	3.146e-50	191.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
LZS3_k127_6639480_5	1340493.JNIF01000003_gene3743	2.223e-122	401.0	COG1172@1|root,COG1172@2|Bacteria,3Y5DG@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
LZS3_k127_6639480_4	999541.bgla_2g08310	5.343e-138	454.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2VHRA@28216|Betaproteobacteria,1JZXK@119060|Burkholderiaceae	28216|Betaproteobacteria	P	import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
LZS3_k127_6639480_25	234267.Acid_1907	0.0001385	53.0	2FA03@1|root,34298@2|Bacteria,3Y84H@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6639480_17	857293.CAAU_2259	4.392e-53	191.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,36HZE@31979|Clostridiaceae	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
LZS3_k127_6639480_2	526222.Desal_1305	3.979e-199	630.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2M9J9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
LZS3_k127_6639480_20	234267.Acid_0514	2.927e-38	156.0	COG1729@1|root,COG1729@2|Bacteria,3Y3H6@57723|Acidobacteria	57723|Acidobacteria	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
LZS3_k127_6639480_11	234267.Acid_0513	2.113e-77	266.0	COG2885@1|root,COG2885@2|Bacteria,3Y3ZY@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
LZS3_k127_6639480_7	1267535.KB906767_gene573	1.174e-119	399.0	COG0823@1|root,COG0823@2|Bacteria,3Y2RC@57723|Acidobacteria,2JIV3@204432|Acidobacteriia	204432|Acidobacteriia	U	WD40-like Beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS3_k127_6639480_21	1267535.KB906767_gene574	6.125e-36	146.0	COG0810@1|root,COG0810@2|Bacteria,3Y4WH@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
LZS3_k127_6639480_24	234267.Acid_0510	9.257e-27	115.0	COG0848@1|root,COG0848@2|Bacteria,3Y4QV@57723|Acidobacteria	57723|Acidobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS3_k127_6639480_13	234267.Acid_0509	1.187e-64	230.0	COG0811@1|root,COG0811@2|Bacteria,3Y2T8@57723|Acidobacteria	57723|Acidobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
LZS3_k127_6639480_3	234267.Acid_0508	3.254e-153	503.0	COG0497@1|root,COG0497@2|Bacteria,3Y2J4@57723|Acidobacteria	57723|Acidobacteria	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
LZS3_k127_6639480_10	278963.ATWD01000001_gene1679	5.209e-83	293.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HZ@57723|Acidobacteria,2JI47@204432|Acidobacteriia	204432|Acidobacteriia	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6639480_1	1340493.JNIF01000003_gene3652	1.922e-236	751.0	COG1200@1|root,COG1200@2|Bacteria,3Y31Z@57723|Acidobacteria	57723|Acidobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
LZS3_k127_6639480_19	234267.Acid_7762	7.061e-45	169.0	COG0742@1|root,COG0742@2|Bacteria,3Y4K0@57723|Acidobacteria	57723|Acidobacteria	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
LZS3_k127_6639480_0	1340493.JNIF01000004_gene558	1.983e-249	829.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Cytochrom_C,DUF1080,DUF4132,Pkinase
LZS3_k127_6639480_6	1500257.JQNM01000001_gene3364	1.161e-120	403.0	COG0520@1|root,COG0520@2|Bacteria,1MXH1@1224|Proteobacteria,2TQUT@28211|Alphaproteobacteria,4BD1H@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS3_k127_6639480_12	926550.CLDAP_33320	1.257e-65	227.0	2DKWS@1|root,30N64@2|Bacteria,2G8KD@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4188
LZS3_k127_6639480_8	886293.Sinac_5845	4.082e-114	377.0	COG1453@1|root,COG1453@2|Bacteria,2IZF3@203682|Planctomycetes	203682|Planctomycetes	S	aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_6639480_14	234267.Acid_4899	2.811e-64	233.0	COG1376@1|root,COG1376@2|Bacteria,3Y5WR@57723|Acidobacteria	57723|Acidobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS3_k127_6639750_12	1294143.H681_07825	3.849e-19	93.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria	1224|Proteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
LZS3_k127_6639750_3	1346791.M529_04545	5.214e-124	411.0	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2TTHW@28211|Alphaproteobacteria,2K02B@204457|Sphingomonadales	204457|Sphingomonadales	G	Major Facilitator Superfamily	-	-	-	ko:K03535	-	-	-	-	ko00000,ko02000	2.A.1.14.1	-	-	MFS_1
LZS3_k127_6639750_8	1340493.JNIF01000003_gene4590	4.524e-77	273.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FMN_dh
LZS3_k127_6639750_7	1340493.JNIF01000003_gene4590	7.022e-79	278.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FMN_dh
LZS3_k127_6639750_15	161156.JQKW01000006_gene1257	0.0002215	51.0	COG3043@1|root,COG3043@2|Bacteria	2|Bacteria	C	anaerobic respiration	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS3_k127_6639750_2	243231.GSU0474	9.72e-126	431.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg
LZS3_k127_6639750_9	335543.Sfum_1483	3.289e-41	164.0	COG0484@1|root,COG0484@2|Bacteria,1RHHJ@1224|Proteobacteria,42SMN@68525|delta/epsilon subdivisions,2WPJN@28221|Deltaproteobacteria,2MRYE@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
LZS3_k127_6639750_0	234267.Acid_2707	3.305e-133	436.0	COG0542@1|root,COG0542@2|Bacteria,3Y463@57723|Acidobacteria	57723|Acidobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
LZS3_k127_6639750_1	1340493.JNIF01000003_gene3093	5.102e-133	432.0	COG0714@1|root,COG0714@2|Bacteria,3Y4G8@57723|Acidobacteria	57723|Acidobacteria	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS3_k127_6639750_11	1340493.JNIF01000003_gene1319	7.701e-20	98.0	2BZ8T@1|root,33VM1@2|Bacteria,3Y7Y3@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6639750_13	234267.Acid_1753	8.282e-18	93.0	2BZ8T@1|root,33VM1@2|Bacteria,3Y7Y3@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6639750_5	204669.Acid345_2619	1.735e-107	370.0	COG3975@1|root,COG3975@2|Bacteria,3Y411@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
LZS3_k127_6639750_4	700598.Niako_6295	5.759e-124	407.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IWYY@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_6639750_6	886293.Sinac_7190	1.629e-104	359.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,2IXFD@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
LZS3_k127_6685942_14	1089550.ATTH01000001_gene1251	2.415e-12	73.0	COG0286@1|root,COG0286@2|Bacteria,4NH2U@976|Bacteroidetes	976|Bacteroidetes	L	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,Mrr_cat_2,N6_Mtase,ResIII
LZS3_k127_6685942_7	326427.Cagg_3338	3.895e-119	400.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,Peptidase_M56,TPR_19,TPR_8
LZS3_k127_6685942_6	326427.Cagg_3337	1.065e-127	417.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113,2.1.1.37	ko:K00558,ko:K00590	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	Mrr_N,N6_N4_Mtase
LZS3_k127_6685942_13	388467.A19Y_1211	3.948e-18	85.0	COG0286@1|root,COG0286@2|Bacteria,1G36A@1117|Cyanobacteria,1H9DU@1150|Oscillatoriales	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
LZS3_k127_6685942_5	886293.Sinac_2678	1.1e-141	466.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_6685942_12	880073.Calab_2319	1.891e-27	123.0	COG1216@1|root,COG1216@2|Bacteria,2NR8Z@2323|unclassified Bacteria	2|Bacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6685942_11	1142394.PSMK_19720	3.889e-29	130.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6685942_9	234267.Acid_0462	4.268e-49	181.0	COG0712@1|root,COG0712@2|Bacteria,3Y4Z4@57723|Acidobacteria	57723|Acidobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
LZS3_k127_6685942_0	234267.Acid_0463	1.465e-255	796.0	COG0056@1|root,COG0056@2|Bacteria,3Y2R6@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS3_k127_6685942_8	234267.Acid_0464	1.414e-96	324.0	COG0224@1|root,COG0224@2|Bacteria,3Y3MN@57723|Acidobacteria	57723|Acidobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
LZS3_k127_6685942_1	1267535.KB906767_gene3118	3.719e-253	788.0	COG0055@1|root,COG0055@2|Bacteria,3Y2PU@57723|Acidobacteria,2JIDM@204432|Acidobacteriia	204432|Acidobacteriia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS3_k127_6685942_10	234267.Acid_0466	5.219e-34	135.0	COG0355@1|root,COG0355@2|Bacteria,3Y5VV@57723|Acidobacteria	57723|Acidobacteria	C	ATP synthase, Delta/Epsilon chain, beta-sandwich domain	-	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
LZS3_k127_6685942_15	1123487.KB892849_gene277	3.121e-12	71.0	COG2149@1|root,COG2149@2|Bacteria,1NGFR@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
LZS3_k127_6685942_2	1212548.B381_11411	1.485e-191	616.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,1RMI1@1236|Gammaproteobacteria,1Z08C@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	Sodium sulfate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
LZS3_k127_6685942_3	234267.Acid_7666	4.104e-154	499.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_6685942_4	234267.Acid_7665	2.685e-147	490.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
LZS3_k127_6692282_3	1340493.JNIF01000003_gene3901	1.232e-146	470.0	COG0111@1|root,COG0111@2|Bacteria,3Y3VD@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_6692282_0	234267.Acid_7288	5.377e-172	551.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,3Y4NX@57723|Acidobacteria	57723|Acidobacteria	GM	CoA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
LZS3_k127_6692282_5	497964.CfE428DRAFT_2702	3.436e-113	377.0	COG1878@1|root,COG1878@2|Bacteria	2|Bacteria	S	arylformamidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
LZS3_k127_6692282_2	64471.sync_2679	2.108e-154	501.0	COG0154@1|root,COG0154@2|Bacteria,1G0HS@1117|Cyanobacteria,1GZCX@1129|Synechococcus	1117|Cyanobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS3_k127_6692282_11	1123371.ATXH01000003_gene1945	5.016e-15	87.0	COG0760@1|root,COG0760@2|Bacteria,2GHMC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
LZS3_k127_6692282_7	234267.Acid_0449	4.276e-94	315.0	COG1801@1|root,COG1801@2|Bacteria,3Y2F1@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS3_k127_6692282_6	1123242.JH636435_gene2940	3.262e-110	373.0	COG0673@1|root,COG0673@2|Bacteria,2J1QN@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_6692282_8	234267.Acid_6247	2.541e-88	307.0	COG0673@1|root,COG0673@2|Bacteria,3Y39X@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_6692282_9	234267.Acid_0371	2.635e-76	271.0	2C5RF@1|root,33T7W@2|Bacteria,3Y6IQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6692282_14	234267.Acid_0370	5.472e-08	66.0	2C5RD@1|root,2ZUCI@2|Bacteria,3Y91D@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6692282_10	234267.Acid_0369	3.202e-57	204.0	COG1595@1|root,COG1595@2|Bacteria,3Y7JF@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, luxR family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_6692282_1	1267535.KB906767_gene5217	9.905e-162	517.0	COG0183@1|root,COG0183@2|Bacteria,3Y7RP@57723|Acidobacteria	57723|Acidobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_6692282_13	243232.MJ_1552	6.869e-11	70.0	COG1545@1|root,arCOG01285@2157|Archaea,2XXGF@28890|Euryarchaeota,23QWX@183939|Methanococci	183939|Methanococci	V	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
LZS3_k127_6692282_12	406818.XBJ1_0454	2.582e-12	71.0	COG0553@1|root,COG0553@2|Bacteria,1MX26@1224|Proteobacteria,1RZZU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
LZS3_k127_6692282_4	105559.Nwat_0423	7.594e-120	389.0	COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,1S3TR@1236|Gammaproteobacteria,1X0Z8@135613|Chromatiales	135613|Chromatiales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_6711839_0	1379698.RBG1_1C00001G1218	1.07e-85	305.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS3_k127_6711839_2	502025.Hoch_1576	1.352e-55	203.0	COG1595@1|root,COG1595@2|Bacteria,1RINW@1224|Proteobacteria,4385N@68525|delta/epsilon subdivisions,2X3FI@28221|Deltaproteobacteria,2YVVV@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
LZS3_k127_6711839_4	1379698.RBG1_1C00001G0608	1.381e-10	62.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
LZS3_k127_6711839_6	234267.Acid_1428	3.538e-05	47.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
LZS3_k127_6711839_1	1379698.RBG1_1C00001G1616	8.549e-64	231.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS3_k127_6711839_3	401053.AciPR4_2718	6.717e-39	158.0	COG3710@1|root,COG3710@2|Bacteria,3Y7KB@57723|Acidobacteria,2JMW2@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
LZS3_k127_6733312_9	1487953.JMKF01000053_gene1756	3.166e-134	444.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GAF,GGDEF,PAS_3,Response_reg
LZS3_k127_6733312_7	234267.Acid_7841	2.434e-142	498.0	COG1629@1|root,COG1629@2|Bacteria,3Y78S@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_6733312_5	886293.Sinac_5138	3.455e-177	567.0	COG1690@1|root,COG1690@2|Bacteria,2IWY4@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
LZS3_k127_6733312_17	671143.DAMO_3152	6.443e-28	120.0	COG1371@1|root,COG1371@2|Bacteria,2NPX9@2323|unclassified Bacteria	2|Bacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
LZS3_k127_6733312_12	234267.Acid_0066	5.727e-97	334.0	COG0313@1|root,COG0313@2|Bacteria,3Y32N@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
LZS3_k127_6733312_14	234267.Acid_6142	1.364e-81	276.0	COG1793@1|root,COG1793@2|Bacteria,3Y75X@57723|Acidobacteria	57723|Acidobacteria	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_6733312_13	234267.Acid_6142	4.35e-87	293.0	COG1793@1|root,COG1793@2|Bacteria,3Y75X@57723|Acidobacteria	57723|Acidobacteria	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_6733312_16	1232410.KI421428_gene1022	1.223e-48	187.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,42W88@68525|delta/epsilon subdivisions,2WRBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
LZS3_k127_6733312_15	1340493.JNIF01000003_gene3499	5.31e-52	199.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	pepQ	-	3.5.3.3	ko:K08688	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566	RC00548,RC00549	ko00000,ko00001,ko01000	-	-	-	Creatinase_N,Peptidase_M24
LZS3_k127_6733312_3	344747.PM8797T_10489	5.08e-213	675.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2IXEZ@203682|Planctomycetes	203682|Planctomycetes	P	COG0491 Zn-dependent	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
LZS3_k127_6733312_4	234267.Acid_7276	9.812e-185	594.0	COG0028@1|root,COG0028@2|Bacteria,3Y3GJ@57723|Acidobacteria	2|Bacteria	EH	PFAM Thiamine pyrophosphate	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_6733312_2	234267.Acid_0003	0.0	1114.0	COG0187@1|root,COG0187@2|Bacteria,3Y369@57723|Acidobacteria	57723|Acidobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
LZS3_k127_6733312_10	1267535.KB906767_gene3182	3.334e-127	417.0	COG0592@1|root,COG0592@2|Bacteria,3Y2WE@57723|Acidobacteria,2JI4X@204432|Acidobacteriia	204432|Acidobacteriia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
LZS3_k127_6733312_6	234267.Acid_0001	1.149e-158	512.0	COG0593@1|root,COG0593@2|Bacteria,3Y2HA@57723|Acidobacteria	57723|Acidobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS3_k127_6733312_11	234267.Acid_3974	2.639e-123	400.0	COG1606@1|root,COG1606@2|Bacteria,3Y30C@57723|Acidobacteria	57723|Acidobacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
LZS3_k127_6733312_1	234267.Acid_3975	0.0	1122.0	COG0188@1|root,COG0188@2|Bacteria,3Y2G5@57723|Acidobacteria	57723|Acidobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS3_k127_6733312_8	1340493.JNIF01000003_gene1313	2.702e-140	460.0	COG0673@1|root,COG0673@2|Bacteria,3Y4RG@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_6733312_0	234267.Acid_0587	0.0	1254.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
LZS3_k127_6737591_2	234267.Acid_7047	2.681e-70	255.0	2F7Z0@1|root,340CS@2|Bacteria,3Y88S@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6737591_0	247490.KSU1_C0714	3.959e-149	507.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
LZS3_k127_6737591_3	234267.Acid_2904	4.668e-39	169.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
LZS3_k127_6737591_1	391600.ABRU01000008_gene2773	4.094e-85	296.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,2TTUZ@28211|Alphaproteobacteria,2KFTZ@204458|Caulobacterales	204458|Caulobacterales	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
LZS3_k127_6751059_0	886293.Sinac_5110	2.003e-235	740.0	COG3119@1|root,COG3119@2|Bacteria,2IXSN@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_6751059_1	886293.Sinac_0388	8.752e-132	428.0	COG1621@1|root,COG1621@2|Bacteria,2IZ2Q@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6751059_3	1267535.KB906767_gene343	2.123e-19	91.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS3_k127_6751059_2	1340493.JNIF01000003_gene2519	1.717e-63	234.0	COG0457@1|root,COG0457@2|Bacteria,3Y7UM@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS3_k127_6751059_4	1267535.KB906767_gene703	1.466e-18	97.0	28MK6@1|root,33VBX@2|Bacteria,3Y7JM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6763621_7	525268.HMPREF0308_0203	0.0009645	43.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
LZS3_k127_6763621_2	1267535.KB906767_gene4901	3.273e-156	508.0	COG0468@1|root,COG0468@2|Bacteria,3Y3Y1@57723|Acidobacteria,2JHU1@204432|Acidobacteriia	204432|Acidobacteriia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
LZS3_k127_6763621_4	234267.Acid_7266	1.55e-103	345.0	COG2304@1|root,COG2304@2|Bacteria,3Y30G@57723|Acidobacteria	57723|Acidobacteria	S	PFAM von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
LZS3_k127_6763621_5	1267535.KB906767_gene4449	4.95e-98	329.0	COG0564@1|root,COG0564@2|Bacteria,3Y3G8@57723|Acidobacteria,2JHXC@204432|Acidobacteriia	204432|Acidobacteriia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS3_k127_6763621_1	324602.Caur_3724	4.287e-162	523.0	COG2239@1|root,COG2239@2|Bacteria,2G6H7@200795|Chloroflexi,376RI@32061|Chloroflexia	32061|Chloroflexia	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
LZS3_k127_6763621_3	234267.Acid_7362	2.458e-113	373.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	2|Bacteria	M	PFAM Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
LZS3_k127_6763621_6	156889.Mmc1_2788	1.7e-37	158.0	COG1262@1|root,COG4461@1|root,COG1262@2|Bacteria,COG4461@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
LZS3_k127_6802172_3	234267.Acid_1440	2.112e-47	176.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	6.5.1.3	ko:K14680	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos_2,RNA_lig_T4_1
LZS3_k127_6802172_0	234267.Acid_6640	2.952e-132	442.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,3Y2V9@57723|Acidobacteria	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	ko:K02584,ko:K07713,ko:K15836,ko:K21009	ko02020,ko02025,map02020,map02025	M00499	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	GAF,GAF_2,HTH_8,PocR,Sigma54_activat,Yop-YscD_cpl
LZS3_k127_6802172_2	1379698.RBG1_1C00001G1218	2.838e-91	332.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS3_k127_6802172_1	1379698.RBG1_1C00001G1616	3.615e-94	321.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS3_k127_6812500_2	1267535.KB906767_gene361	5.241e-140	458.0	COG0673@1|root,COG0673@2|Bacteria,3Y6Q3@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_6812500_0	234267.Acid_1533	0.0	1052.0	COG2866@1|root,COG2866@2|Bacteria,3Y416@57723|Acidobacteria	57723|Acidobacteria	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
LZS3_k127_6812500_1	234267.Acid_7215	1.194e-182	584.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_6812500_3	58344.JOEL01000020_gene5134	1.201e-39	151.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria	201174|Actinobacteria	E	gamma-glutamyltransferase	ggt1	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_6821536_28	1121921.KB898706_gene2406	2.006e-06	61.0	COG0729@1|root,COG0729@2|Bacteria,1R5Y3@1224|Proteobacteria,1RPB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
LZS3_k127_6821536_17	682795.AciX8_3485	3.391e-64	248.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
LZS3_k127_6821536_13	682795.AciX8_3484	1.89e-72	258.0	COG1127@1|root,COG1127@2|Bacteria,3Y45H@57723|Acidobacteria,2JHWI@204432|Acidobacteriia	204432|Acidobacteriia	Q	pfam abc	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
LZS3_k127_6821536_12	682795.AciX8_3483	1.581e-76	264.0	COG0767@1|root,COG0767@2|Bacteria,3Y43S@57723|Acidobacteria,2JI8E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Belongs to the MlaE permease family	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
LZS3_k127_6821536_5	1340493.JNIF01000003_gene3118	7.665e-150	514.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,Plug,TonB_dep_Rec
LZS3_k127_6821536_23	234267.Acid_7037	1.332e-28	128.0	COG0468@1|root,COG0468@2|Bacteria,3Y4QB@57723|Acidobacteria	57723|Acidobacteria	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
LZS3_k127_6821536_19	278963.ATWD01000001_gene1106	1.971e-49	201.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria,2JIUC@204432|Acidobacteriia	204432|Acidobacteriia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
LZS3_k127_6821536_25	1198114.AciX9_0248	3.141e-15	78.0	COG1848@1|root,COG1848@2|Bacteria,3Y5NW@57723|Acidobacteria,2JJY1@204432|Acidobacteriia	204432|Acidobacteriia	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS3_k127_6821536_29	1184609.KILIM_084_00210	0.0002768	48.0	2DGZX@1|root,2ZXWY@2|Bacteria,2HDW7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6821536_0	234267.Acid_7035	0.0	1128.0	COG0587@1|root,COG0587@2|Bacteria,3Y3YK@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the DNA polymerase type-C family. DnaE2 subfamily	-	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS3_k127_6821536_3	886293.Sinac_5344	2.491e-231	739.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81,3.5.2.3	ko:K01465,ko:K06015	ko00240,ko01100,map00240,map01100	M00051	R01993,R02192	RC00064,RC00328,RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
LZS3_k127_6821536_21	234267.Acid_5858	1.198e-30	127.0	COG0500@1|root,COG0500@2|Bacteria,3Y94A@57723|Acidobacteria	57723|Acidobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6821536_7	234267.Acid_7936	4.792e-136	447.0	COG1566@1|root,COG1566@2|Bacteria,3Y9B7@57723|Acidobacteria	57723|Acidobacteria	V	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
LZS3_k127_6821536_9	234267.Acid_7937	8.582e-123	403.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria	57723|Acidobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_6821536_10	1267535.KB906767_gene4898	8.696e-116	381.0	COG0667@1|root,COG0667@2|Bacteria,3Y2KB@57723|Acidobacteria,2JJ0N@204432|Acidobacteriia	2|Bacteria	C	aldo keto reductase	fdh	-	1.1.1.316	ko:K17744	ko00053,ko01100,ko01110,map00053,map01100,map01110	M00114	R07675	RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
LZS3_k127_6821536_6	234267.Acid_1905	5.223e-137	470.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
LZS3_k127_6821536_4	234267.Acid_1906	2.093e-180	605.0	COG1074@1|root,COG1074@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase activity	-	-	3.1.11.5,3.6.4.12	ko:K01144,ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF3799,PDDEXK_1,UvrD-helicase,UvrD_C
LZS3_k127_6821536_24	234267.Acid_5251	2.252e-26	117.0	COG1286@1|root,COG1286@2|Bacteria,3Y8DX@57723|Acidobacteria	57723|Acidobacteria	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
LZS3_k127_6821536_8	204669.Acid345_2258	3.782e-124	406.0	COG0152@1|root,COG0152@2|Bacteria,3Y2KX@57723|Acidobacteria,2JIG6@204432|Acidobacteriia	204432|Acidobacteriia	F	SAICAR synthetase	purC	-	6.3.2.6,6.3.4.13	ko:K01923,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
LZS3_k127_6821536_18	1192034.CAP_6382	1.201e-54	203.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,4309M@68525|delta/epsilon subdivisions,2WV9K@28221|Deltaproteobacteria,2Z3A1@29|Myxococcales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
LZS3_k127_6821536_2	204669.Acid345_0762	8.26e-236	749.0	COG1529@1|root,COG1529@2|Bacteria,3Y2ME@57723|Acidobacteria,2JIZI@204432|Acidobacteriia	204432|Acidobacteriia	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS3_k127_6821536_11	234267.Acid_2421	7.89e-114	378.0	COG1319@1|root,COG1319@2|Bacteria,3Y3NU@57723|Acidobacteria	57723|Acidobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS3_k127_6821536_20	204669.Acid345_0765	2.098e-46	176.0	COG5588@1|root,COG5588@2|Bacteria,3Y7RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
LZS3_k127_6821536_22	234267.Acid_7948	5.646e-30	127.0	2E6AH@1|root,330YD@2|Bacteria,3Y8MQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6821536_16	204669.Acid345_1221	1.322e-67	233.0	COG0048@1|root,COG0048@2|Bacteria,3Y4JQ@57723|Acidobacteria,2JJ7D@204432|Acidobacteriia	204432|Acidobacteriia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
LZS3_k127_6821536_15	1267535.KB906767_gene2708	6.466e-68	235.0	COG0049@1|root,COG0049@2|Bacteria,3Y3FF@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
LZS3_k127_6821536_1	204669.Acid345_1223	1.343e-319	990.0	COG0480@1|root,COG0480@2|Bacteria,3Y2YX@57723|Acidobacteria,2JIQP@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS3_k127_6821536_27	1267533.KB906734_gene3641	1.515e-10	61.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria,2JKFY@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS3_k127_6853646_0	234267.Acid_2975	1.712e-131	454.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_6853646_1	1198452.Jab_1c19640	5.24e-21	109.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,2WBDI@28216|Betaproteobacteria,475K6@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
LZS3_k127_6853646_2	1267533.KB906738_gene2307	4.209e-08	66.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS3_k127_6854642_1	234267.Acid_3736	6.883e-112	380.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,GSu_C4xC__C2xCH,SdrD_B
LZS3_k127_6854642_4	401053.AciPR4_4121	5.041e-33	133.0	COG3727@1|root,COG3727@2|Bacteria	2|Bacteria	L	T/G mismatch-specific endonuclease activity	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,Vsr
LZS3_k127_6854642_0	483219.LILAB_25350	9.952e-148	473.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,42TVH@68525|delta/epsilon subdivisions,2WR7Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
LZS3_k127_6854642_3	204669.Acid345_1129	8.353e-72	251.0	COG1403@1|root,COG1403@2|Bacteria,3Y79S@57723|Acidobacteria,2JMDD@204432|Acidobacteriia	204432|Acidobacteriia	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS3_k127_6854642_2	234267.Acid_6291	1.311e-78	272.0	COG0457@1|root,COG0789@1|root,COG0457@2|Bacteria,COG0789@2|Bacteria,3Y3EM@57723|Acidobacteria	57723|Acidobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS3_k127_6854642_5	1229203.KI301992_gene798	6.092e-32	127.0	COG1376@1|root,COG1376@2|Bacteria,2GJBA@201174|Actinobacteria	201174|Actinobacteria	L	ErfK YbiS YcfS YnhG family protein	lppS	-	-	-	-	-	-	-	-	-	-	-	YkuD
LZS3_k127_6867387_7	1173022.Cri9333_4514	1.739e-53	198.0	COG2215@1|root,COG2215@2|Bacteria,1G36H@1117|Cyanobacteria,1H9XA@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	-	-	-	ko:K08970	-	-	-	-	ko00000,ko02000	2.A.52.2	-	-	DsbD_2,NicO
LZS3_k127_6867387_3	1122223.KB890698_gene952	1.87e-110	365.0	COG0111@1|root,COG0111@2|Bacteria,1WJ6E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.310	ko:K16843	ko00270,map00270	-	R05693	RC00031	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_6867387_2	1267535.KB906767_gene1747	8.298e-120	390.0	COG0777@1|root,COG0777@2|Bacteria,3Y2U9@57723|Acidobacteria,2JI81@204432|Acidobacteriia	204432|Acidobacteriia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS3_k127_6867387_1	234267.Acid_5660	3.457e-121	402.0	COG0285@1|root,COG0285@2|Bacteria,3Y3ZA@57723|Acidobacteria	57723|Acidobacteria	H	Mur ligase, middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS3_k127_6867387_6	1267535.KB906767_gene3783	2.423e-62	222.0	COG0204@1|root,COG0204@2|Bacteria,3Y4EM@57723|Acidobacteria,2JJ6E@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_6867387_0	234267.Acid_4069	5.867e-227	711.0	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
LZS3_k127_6867387_5	1128421.JAGA01000002_gene1557	3.726e-79	277.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
LZS3_k127_6867387_4	234267.Acid_0818	7.274e-83	285.0	COG1105@1|root,COG1105@2|Bacteria,3Y5F9@57723|Acidobacteria	57723|Acidobacteria	G	Phosphomethylpyrimidine kinase	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
LZS3_k127_6867387_9	1267533.KB906745_gene70	1.324e-30	135.0	COG3218@1|root,COG3218@2|Bacteria	2|Bacteria	Q	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
LZS3_k127_6867387_10	706587.Desti_4742	2.2e-21	96.0	2EH48@1|root,33AW7@2|Bacteria,1NIYU@1224|Proteobacteria,42XKK@68525|delta/epsilon subdivisions,2WSKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6867387_8	1268072.PSAB_20225	7.133e-51	195.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,26VB1@186822|Paenibacillaceae	91061|Bacilli	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_6867387_11	1205680.CAKO01000040_gene680	0.0009916	48.0	COG2329@1|root,COG2329@2|Bacteria,1NDM8@1224|Proteobacteria,2UG48@28211|Alphaproteobacteria,2JY9Y@204441|Rhodospirillales	204441|Rhodospirillales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6885824_3	234267.Acid_5979	8.113e-228	727.0	COG2366@1|root,COG2366@2|Bacteria,3Y2PX@57723|Acidobacteria	2|Bacteria	S	PFAM peptidase S45 penicillin amidase	penA	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
LZS3_k127_6885824_4	234267.Acid_6424	9.564e-153	517.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,3Y3VQ@57723|Acidobacteria	57723|Acidobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
LZS3_k127_6885824_0	234267.Acid_1665	0.0	1500.0	COG0209@1|root,COG0209@2|Bacteria,3Y3Q1@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
LZS3_k127_6885824_1	234267.Acid_3106	3.28e-318	990.0	28HBM@1|root,2Z7NK@2|Bacteria,3Y6H0@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6885824_2	1267535.KB906767_gene3483	3.527e-303	964.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_6912458_5	498761.HM1_0559	2.07e-112	379.0	COG0745@1|root,COG0784@1|root,COG2770@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS3_k127_6912458_8	234267.Acid_6753	3.041e-90	308.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria,3Y4DW@57723|Acidobacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	rsbW	-	2.7.11.1,3.4.21.53	ko:K01338,ko:K04757,ko:K06379,ko:K08282,ko:K17752	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01001,ko01002,ko03021	-	-	-	HATPase_c_2,HTH_8,Response_reg
LZS3_k127_6912458_14	1121405.dsmv_1389	2.992e-51	197.0	COG0477@1|root,COG2814@2|Bacteria,1QUTR@1224|Proteobacteria,42RH5@68525|delta/epsilon subdivisions,2X73Z@28221|Deltaproteobacteria,2MHZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
LZS3_k127_6912458_19	515635.Dtur_1556	3.632e-16	91.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6912458_16	1267535.KB906767_gene3595	2.175e-46	179.0	COG2885@1|root,COG2885@2|Bacteria,3Y2WJ@57723|Acidobacteria,2JJYF@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS3_k127_6912458_17	240015.ACP_3082	1.363e-29	119.0	COG0254@1|root,COG0254@2|Bacteria,3Y5BI@57723|Acidobacteria,2JP2A@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
LZS3_k127_6912458_9	886377.Murru_2673	3.821e-84	288.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
LZS3_k127_6912458_0	234267.Acid_6709	3.305e-223	730.0	COG1404@1|root,COG1404@2|Bacteria,3Y5WB@57723|Acidobacteria	57723|Acidobacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
LZS3_k127_6912458_21	1267535.KB906767_gene1155	2.806e-07	56.0	290CR@1|root,2ZN27@2|Bacteria,3Y8Z2@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6912458_20	234267.Acid_2524	1.992e-09	60.0	2E0FE@1|root,32W1M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
LZS3_k127_6912458_7	886293.Sinac_2371	5.976e-94	319.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	DUF294,NTP_transf_2
LZS3_k127_6912458_12	1267535.KB906767_gene1969	1.491e-68	239.0	COG1082@1|root,COG1708@1|root,COG1082@2|Bacteria,COG1708@2|Bacteria,3Y811@57723|Acidobacteria,2JMZ0@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6912458_1	1123242.JH636434_gene4865	2.847e-157	503.0	COG4948@1|root,COG4948@2|Bacteria,2IYKA@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_6912458_4	886293.Sinac_6961	1.355e-117	394.0	COG2271@1|root,COG2271@2|Bacteria,2IYAW@203682|Planctomycetes	203682|Planctomycetes	G	Major facilitator superfamily	-	-	-	ko:K03535,ko:K08194	-	-	-	-	ko00000,ko02000	2.A.1.14.1,2.A.1.14.7	-	-	MFS_1
LZS3_k127_6912458_15	234267.Acid_7367	5.599e-48	184.0	COG1266@1|root,COG1266@2|Bacteria,3Y4ED@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS3_k127_6912458_11	1340493.JNIF01000003_gene2960	1.342e-68	245.0	2D61V@1|root,32TKB@2|Bacteria,3Y5CF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6912458_2	234267.Acid_7375	1.975e-150	482.0	COG0057@1|root,COG0057@2|Bacteria,3Y2QC@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
LZS3_k127_6912458_3	234267.Acid_4421	1.394e-148	479.0	COG0126@1|root,COG0126@2|Bacteria,3Y2T7@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
LZS3_k127_6912458_6	1357399.HMPREF2087_00802	5.118e-97	322.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA,Methyltransf_23,Methyltransf_31
LZS3_k127_6912458_10	234267.Acid_0701	4.996e-73	251.0	COG1413@1|root,COG1413@2|Bacteria,3Y7N7@57723|Acidobacteria	57723|Acidobacteria	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_6912458_13	1408424.JHYI01000004_gene3561	4.062e-59	210.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HGYP@91061|Bacilli,1ZQBI@1386|Bacillus	91061|Bacilli	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
LZS3_k127_6912458_18	278963.ATWD01000002_gene260	4.754e-18	88.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KD@57723|Acidobacteria,2JIB2@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_6925508_27	794903.OPIT5_15790	3.797e-21	95.0	COG2271@1|root,COG2271@2|Bacteria,46UQA@74201|Verrucomicrobia,3K8MQ@414999|Opitutae	414999|Opitutae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_6925508_21	886293.Sinac_6105	8.717e-64	227.0	COG4221@1|root,COG4221@2|Bacteria,2IYVR@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_6925508_34	1267535.KB906767_gene4029	2.639e-05	50.0	2CHJJ@1|root,2ZDZ3@2|Bacteria,3Y94T@57723|Acidobacteria	57723|Acidobacteria	S	PFAM type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6925508_12	1267535.KB906767_gene5504	3.418e-106	353.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_6925508_7	1340493.JNIF01000004_gene393	1.676e-129	430.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
LZS3_k127_6925508_14	314230.DSM3645_21427	3.04e-96	329.0	COG1387@1|root,COG2755@1|root,COG1387@2|Bacteria,COG2755@2|Bacteria,2IXFZ@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_6925508_2	401053.AciPR4_2853	1.023e-171	569.0	COG1629@1|root,COG4771@2|Bacteria,3Y461@57723|Acidobacteria,2JHPM@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_6925508_22	1173026.Glo7428_4141	9.839e-59	222.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS3_k127_6925508_8	429009.Adeg_0173	4.655e-124	412.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6925508_11	700598.Niako_0563	1.46e-114	381.0	COG4409@1|root,COG4409@2|Bacteria,4NFNK@976|Bacteroidetes,1IRAJ@117747|Sphingobacteriia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
LZS3_k127_6925508_13	1382306.JNIM01000001_gene2669	8.238e-104	359.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_6925508_6	1123242.JH636435_gene1875	6.868e-131	429.0	COG3964@1|root,COG3964@2|Bacteria	2|Bacteria	S	amidohydrolase	dho	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_6925508_5	1267535.KB906767_gene216	1.912e-134	440.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
LZS3_k127_6925508_3	641524.ADICYQ_0168	2.179e-168	543.0	COG5476@1|root,COG5476@2|Bacteria,4NKYT@976|Bacteroidetes,47XQY@768503|Cytophagia	976|Bacteroidetes	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
LZS3_k127_6925508_26	1267535.KB906767_gene1676	2.363e-36	150.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS3_k127_6925508_17	234267.Acid_7049	2.769e-78	271.0	COG1451@1|root,COG1451@2|Bacteria,3Y2SM@57723|Acidobacteria	57723|Acidobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6925508_9	234267.Acid_6381	2.215e-115	390.0	COG0859@1|root,COG0859@2|Bacteria,3Y6NF@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_6925508_1	234267.Acid_6497	5.45e-176	580.0	COG1519@1|root,COG1663@1|root,COG1519@2|Bacteria,COG1663@2|Bacteria,3Y3X5@57723|Acidobacteria	57723|Acidobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N,LpxK
LZS3_k127_6925508_29	330214.NIDE3521	7.287e-14	83.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HDOD,HisKA,Response_reg
LZS3_k127_6925508_35	1227352.C173_31821	0.0005419	53.0	COG4689@1|root,COG4689@2|Bacteria,1VW7Z@1239|Firmicutes,4I17W@91061|Bacilli,26RSZ@186822|Paenibacillaceae	91061|Bacilli	Q	Acetoacetate decarboxylase (ADC)	adc	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
LZS3_k127_6925508_33	105422.BBPM01000003_gene5658	1.115e-05	58.0	COG4689@1|root,COG4689@2|Bacteria,2I8M2@201174|Actinobacteria,2NF7T@228398|Streptacidiphilus	201174|Actinobacteria	Q	Acetoacetate decarboxylase (ADC)	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
LZS3_k127_6925508_32	1123024.AUII01000006_gene4727	1.502e-08	58.0	2DS3D@1|root,33EC4@2|Bacteria,2GXNR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6925508_31	1205680.CAKO01000035_gene261	5.269e-12	70.0	2E6FA@1|root,3312Q@2|Bacteria,1NCPQ@1224|Proteobacteria,2UKWD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6925508_23	234267.Acid_1597	1.097e-53	199.0	COG2930@1|root,COG2930@2|Bacteria	2|Bacteria	S	regulation of ruffle assembly	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
LZS3_k127_6925508_16	272134.KB731324_gene4206	3.686e-86	295.0	COG1125@1|root,COG1125@2|Bacteria,1G21Q@1117|Cyanobacteria,1HA99@1150|Oscillatoriales	1117|Cyanobacteria	E	SMART ATPase, AAA type, core	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
LZS3_k127_6925508_19	118173.KB235914_gene3320	1.669e-72	250.0	COG1174@1|root,COG1174@2|Bacteria,1G2ZA@1117|Cyanobacteria,1HAQ8@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
LZS3_k127_6925508_25	1267533.KB906737_gene1775	1.261e-39	151.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
LZS3_k127_6925508_24	379066.GAU_0459	4.017e-45	169.0	COG1846@1|root,COG1846@2|Bacteria,1ZU5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
LZS3_k127_6925508_0	234267.Acid_3891	3.537e-180	585.0	COG1228@1|root,COG4642@1|root,COG1228@2|Bacteria,COG4642@2|Bacteria,3Y539@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS3_k127_6925508_18	335543.Sfum_2673	7.369e-74	263.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
LZS3_k127_6925508_20	382464.ABSI01000013_gene1504	1.277e-69	248.0	COG1638@1|root,COG1638@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
LZS3_k127_6925508_4	290397.Adeh_3981	4.941e-156	511.0	COG1593@1|root,COG3090@1|root,COG1593@2|Bacteria,COG3090@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2YWE1@29|Myxococcales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
LZS3_k127_6926657_3	1356852.N008_01765	7.76e-63	242.0	COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,47P2Z@768503|Cytophagia	976|Bacteroidetes	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GTA_TIM
LZS3_k127_6926657_6	234267.Acid_2904	3.019e-47	193.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
LZS3_k127_6926657_8	57918.XP_004288499.1	0.0002269	54.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37MB0@33090|Viridiplantae,3GFCB@35493|Streptophyta,4JKX4@91835|fabids	35493|Streptophyta	O	metalloendoproteinase 1-like	-	-	3.4.24.34	ko:K01402,ko:K07999	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PG_binding_1,Peptidase_M10
LZS3_k127_6926657_7	215803.DB30_6679	3.26e-13	78.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria,439MQ@68525|delta/epsilon subdivisions,2X4YU@28221|Deltaproteobacteria,2YZV4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6926657_0	1267535.KB906767_gene2278	7.23e-156	505.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
LZS3_k127_6926657_4	1210884.HG799462_gene7872	1.843e-55	202.0	COG0095@1|root,COG0095@2|Bacteria,2J0D8@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
LZS3_k127_6926657_5	234267.Acid_7445	7.459e-53	198.0	COG0589@1|root,COG0589@2|Bacteria,3Y5Y7@57723|Acidobacteria	57723|Acidobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_6926657_1	56780.SYN_00323	1.085e-141	460.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,42R1V@68525|delta/epsilon subdivisions,2WN7S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
LZS3_k127_6926657_2	1382303.JPOM01000001_gene1755	9.987e-112	372.0	COG0863@1|root,COG0863@2|Bacteria,1PCSX@1224|Proteobacteria,2VDM9@28211|Alphaproteobacteria,2KJFE@204458|Caulobacterales	204458|Caulobacterales	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
LZS3_k127_6963427_28	1122939.ATUD01000006_gene1711	1.933e-06	52.0	COG0438@1|root,COG2227@1|root,COG0438@2|Bacteria,COG2227@2|Bacteria,2GUEW@201174|Actinobacteria,4CPRR@84995|Rubrobacteria	84995|Rubrobacteria	MQ	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Methyltransf_23
LZS3_k127_6963427_16	290399.Arth_1238	7.404e-48	188.0	COG2327@1|root,COG2327@2|Bacteria,2IR3S@201174|Actinobacteria,1WBFF@1268|Micrococcaceae	201174|Actinobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	ko:K16710	-	-	-	-	ko00000	-	-	-	PS_pyruv_trans
LZS3_k127_6963427_24	1174528.JH992898_gene1127	3.858e-28	119.0	2DQ7S@1|root,3355J@2|Bacteria,1GA7T@1117|Cyanobacteria	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
LZS3_k127_6963427_27	1170562.Cal6303_1906	1.476e-19	92.0	2DRDY@1|root,33BC0@2|Bacteria	2|Bacteria	S	PFAM Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
LZS3_k127_6963427_17	1121939.L861_02695	2.836e-42	169.0	COG1493@1|root,COG1493@2|Bacteria,1NN8Y@1224|Proteobacteria,1SGEG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6963427_21	1449065.JMLL01000010_gene76	3.961e-37	156.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,43HWU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
LZS3_k127_6963427_14	743722.Sph21_1081	1.855e-51	199.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
LZS3_k127_6963427_6	671143.DAMO_0699	1.539e-157	509.0	COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
LZS3_k127_6963427_9	234267.Acid_0811	1.166e-98	331.0	COG1082@1|root,COG1082@2|Bacteria,3Y88X@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_6963427_11	1210884.HG799478_gene15504	1.349e-91	311.0	COG0451@1|root,COG0451@2|Bacteria,2IYKN@203682|Planctomycetes	203682|Planctomycetes	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_6963427_22	710696.Intca_3029	8.618e-35	142.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,4FIFT@85021|Intrasporangiaceae	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
LZS3_k127_6963427_26	1449080.JQMV01000003_gene1667	2.445e-20	95.0	COG0662@1|root,COG0662@2|Bacteria,1WK83@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_6963427_10	234267.Acid_0228	5.348e-95	329.0	COG2890@1|root,COG2890@2|Bacteria,3Y8Q3@57723|Acidobacteria	2|Bacteria	J	Pfam:Methyltransf_26	rsmC	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	MTS
LZS3_k127_6963427_13	1267535.KB906767_gene2491	2.478e-74	253.0	COG3516@1|root,COG3516@2|Bacteria,3Y4M4@57723|Acidobacteria,2JMP8@204432|Acidobacteriia	204432|Acidobacteriia	S	Type VI secretion system, VipA, VC_A0107 or Hcp2	-	-	-	ko:K11901	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VipA
LZS3_k127_6963427_2	234267.Acid_0232	1.452e-258	803.0	COG3517@1|root,COG3517@2|Bacteria,3Y2RM@57723|Acidobacteria	57723|Acidobacteria	S	Type VI secretion protein, EvpB/VC_A0108, tail sheath	-	-	-	ko:K11900	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	VipB
LZS3_k127_6963427_15	765911.Thivi_2288	5.974e-51	185.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,1S39K@1236|Gammaproteobacteria,1WYR2@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM Type VI secretion system effector, Hcp1	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
LZS3_k127_6963427_12	234267.Acid_0234	1.089e-89	301.0	COG4455@1|root,COG4455@2|Bacteria,3Y73H@57723|Acidobacteria	57723|Acidobacteria	S	ImpE protein	-	-	-	ko:K11898	-	-	-	-	ko00000,ko02044	-	-	-	ImpE
LZS3_k127_6963427_4	234267.Acid_0235	1.551e-190	612.0	COG3515@1|root,COG3515@2|Bacteria,3Y2NF@57723|Acidobacteria	57723|Acidobacteria	S	ImpA, N-terminal, type VI secretion system	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N,T6SS_VasJ
LZS3_k127_6963427_20	234267.Acid_0236	1.288e-38	150.0	COG3518@1|root,COG3518@2|Bacteria,3Y5IK@57723|Acidobacteria	57723|Acidobacteria	S	Gene 25-like lysozyme	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
LZS3_k127_6963427_1	234267.Acid_0237	1.366e-264	827.0	COG3519@1|root,COG3519@2|Bacteria,3Y34T@57723|Acidobacteria	57723|Acidobacteria	S	Type VI secretion system, TssF	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
LZS3_k127_6963427_8	1267535.KB906767_gene2498	2.85e-104	351.0	COG3520@1|root,COG3520@2|Bacteria,3Y49W@57723|Acidobacteria,2JMM9@204432|Acidobacteriia	204432|Acidobacteriia	S	type VI secretion protein, VC_A0111 family	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
LZS3_k127_6963427_0	1379270.AUXF01000002_gene1090	0.0	1109.0	COG0542@1|root,COG0542@2|Bacteria,1ZUAF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K11907	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	AAA,AAA_2,ClpB_D2-small
LZS3_k127_6963427_5	330214.NIDE1987	7.33e-187	615.0	COG3501@1|root,COG4253@1|root,COG3501@2|Bacteria,COG4253@2|Bacteria,3J13S@40117|Nitrospirae	40117|Nitrospirae	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
LZS3_k127_6963427_30	446466.Cfla_1367	2.58e-05	54.0	2DST7@1|root,33HCA@2|Bacteria,2GZZ0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6963427_18	357808.RoseRS_1664	3.789e-39	147.0	COG4104@1|root,COG4104@2|Bacteria	2|Bacteria	T	PAAR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif
LZS3_k127_6963427_29	521045.Kole_1275	3.205e-06	51.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K03589,ko:K07491	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	Y1_Tnp
LZS3_k127_6963427_19	477228.YO5_18062	6.491e-39	155.0	2DBKS@1|root,2Z9UX@2|Bacteria,1NTVA@1224|Proteobacteria,1SJCQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6963427_23	1340493.JNIF01000003_gene3331	2.087e-32	132.0	COG1943@1|root,COG1943@2|Bacteria,3Y81S@57723|Acidobacteria	57723|Acidobacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS3_k127_6963427_25	886293.Sinac_2092	1.293e-27	118.0	28KEJ@1|root,2ZA0T@2|Bacteria,2J2GX@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6963427_3	1340493.JNIF01000003_gene3118	5.74e-215	709.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,Plug,TonB_dep_Rec
LZS3_k127_696696_3	471854.Dfer_1712	1.712e-122	414.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF4091,Laminin_G_3,Lipase_GDSL_2,Peptidase_C25
LZS3_k127_696696_1	1340493.JNIF01000003_gene4387	5.154e-172	551.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_696696_0	1267535.KB906767_gene929	8.46e-248	784.0	COG0488@1|root,COG0488@2|Bacteria,3Y340@57723|Acidobacteria,2JI2P@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
LZS3_k127_696696_2	1267535.KB906767_gene218	3.405e-137	450.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6998887_7	268739.Nmlp_1496	7.244e-13	73.0	COG0454@1|root,arCOG00834@2157|Archaea,2XX9M@28890|Euryarchaeota,23VX1@183963|Halobacteria	183963|Halobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6998887_2	1329516.JPST01000030_gene2938	1.537e-133	443.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli,27AWS@186824|Thermoactinomycetaceae	91061|Bacilli	C	Acetokinase family	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
LZS3_k127_6998887_4	880073.Calab_0626	1.429e-99	332.0	COG1250@1|root,COG1250@2|Bacteria,2NQAW@2323|unclassified Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd2	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
LZS3_k127_6998887_5	234267.Acid_6212	1.849e-39	162.0	COG0526@1|root,COG2834@1|root,COG0526@2|Bacteria,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF2092,LolA,Redoxin
LZS3_k127_6998887_3	234267.Acid_7127	3.519e-107	352.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria	57723|Acidobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
LZS3_k127_6998887_6	1340493.JNIF01000003_gene3503	2.594e-33	136.0	COG1430@1|root,COG1430@2|Bacteria,3Y958@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized ACR, COG1430	-	-	-	-	-	-	-	-	-	-	-	-	DUF192
LZS3_k127_6998887_0	1267535.KB906767_gene2867	5.651e-235	745.0	COG0022@1|root,COG0022@2|Bacteria,3Y34Y@57723|Acidobacteria,2JHQ9@204432|Acidobacteriia	2|Bacteria	C	Dehydrogenase E1 component	CP_0743	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
LZS3_k127_6998887_1	1340493.JNIF01000003_gene3118	1.564e-152	513.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,Plug,TonB_dep_Rec
LZS3_k127_7008019_11	927704.SELR_23200	7.487e-17	90.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4H2AC@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS3_k127_7008019_9	234267.Acid_5234	7.383e-49	179.0	COG0295@1|root,COG0295@2|Bacteria,3Y5GE@57723|Acidobacteria	57723|Acidobacteria	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
LZS3_k127_7008019_6	234267.Acid_5233	1.979e-86	294.0	COG0005@1|root,COG0005@2|Bacteria,3Y2MB@57723|Acidobacteria	57723|Acidobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS3_k127_7008019_1	234267.Acid_5232	4.08e-157	513.0	COG1972@1|root,COG1972@2|Bacteria,3Y2KI@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
LZS3_k127_7008019_2	234267.Acid_5231	1.076e-156	505.0	COG0213@1|root,COG0213@2|Bacteria,3Y44B@57723|Acidobacteria	57723|Acidobacteria	F	PFAM Glycosyl transferase, family	-	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
LZS3_k127_7008019_5	1267535.KB906767_gene825	8.298e-100	335.0	COG1940@1|root,COG1940@2|Bacteria,3Y4DD@57723|Acidobacteria,2JJ4T@204432|Acidobacteriia	204432|Acidobacteriia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS3_k127_7008019_0	1267535.KB906767_gene824	4.046e-207	656.0	COG1070@1|root,COG1070@2|Bacteria,3Y2V6@57723|Acidobacteria,2JJ35@204432|Acidobacteriia	204432|Acidobacteriia	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
LZS3_k127_7008019_10	1267535.KB906767_gene4159	1.999e-47	177.0	COG2952@1|root,COG2952@2|Bacteria,3Y55F@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF507)	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
LZS3_k127_7008019_8	1340493.JNIF01000003_gene1829	4.417e-52	194.0	28IJE@1|root,2Z8KB@2|Bacteria,3Y46I@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7008019_3	926550.CLDAP_16520	1.58e-132	432.0	COG4948@1|root,COG4948@2|Bacteria,2G83T@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_7008019_7	1267534.KB906756_gene619	3.756e-74	256.0	2DBQG@1|root,2ZADX@2|Bacteria	2|Bacteria	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_7008019_4	1340493.JNIF01000003_gene2268	8.172e-108	364.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_7008019_12	1169161.KB897719_gene3674	0.0005638	48.0	COG1921@1|root,COG1921@2|Bacteria,2GNZX@201174|Actinobacteria	201174|Actinobacteria	E	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
LZS3_k127_7050068_2	204669.Acid345_2288	5.871e-118	396.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria,2JI77@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS3_k127_7050068_1	234267.Acid_4601	1.33e-141	456.0	COG0524@1|root,COG0524@2|Bacteria,3Y3GE@57723|Acidobacteria	57723|Acidobacteria	G	PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS3_k127_7050068_6	1121875.KB907559_gene534	5.091e-53	201.0	COG0657@1|root,COG0657@2|Bacteria,4NZNT@976|Bacteroidetes	976|Bacteroidetes	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
LZS3_k127_7050068_4	1340493.JNIF01000003_gene4248	7.638e-78	270.0	COG0253@1|root,COG0253@2|Bacteria,3Y4EC@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
LZS3_k127_7050068_0	234267.Acid_4992	2.603e-158	522.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NZ@57723|Acidobacteria	57723|Acidobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_7050068_3	234267.Acid_4994	1.823e-82	283.0	COG0101@1|root,COG0101@2|Bacteria,3Y2MS@57723|Acidobacteria	57723|Acidobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
LZS3_k127_7050068_5	1157490.EL26_21655	1.282e-59	210.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,4HH7Z@91061|Bacilli,279U8@186823|Alicyclobacillaceae	91061|Bacilli	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS3_k127_7147572_7	926566.Terro_3979	1.074e-76	272.0	COG0520@1|root,COG0520@2|Bacteria,3Y3UN@57723|Acidobacteria,2JK05@204432|Acidobacteriia	204432|Acidobacteriia	E	Aminotransferase class-V	-	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
LZS3_k127_7147572_4	234267.Acid_6404	8.694e-102	344.0	COG0457@1|root,COG0457@2|Bacteria,3Y3BD@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TPR_11,TPR_16,TPR_2,TPR_8
LZS3_k127_7147572_6	667014.Thein_2200	1.067e-85	289.0	COG0603@1|root,COG0603@2|Bacteria,2GHPZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
LZS3_k127_7147572_0	1267535.KB906767_gene3825	1.065e-313	996.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_7147572_9	1267535.KB906767_gene3825	3.755e-10	69.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_7147572_1	1267535.KB906767_gene4419	2.442e-150	483.0	COG1186@1|root,COG1186@2|Bacteria,3Y2ZM@57723|Acidobacteria,2JIGW@204432|Acidobacteriia	204432|Acidobacteriia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS3_k127_7147572_2	234267.Acid_1502	5.555e-144	472.0	COG0815@1|root,COG0815@2|Bacteria,3Y4FZ@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS3_k127_7147572_8	1340493.JNIF01000003_gene4333	3.305e-10	68.0	COG3087@1|root,COG3087@2|Bacteria,3Y4WI@57723|Acidobacteria	57723|Acidobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
LZS3_k127_7147572_5	1047013.AQSP01000128_gene429	7.951e-98	327.0	COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria	2|Bacteria	O	prohibitin homologues	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS3_k127_7147572_3	234267.Acid_1498	4.649e-139	454.0	COG1030@1|root,COG1030@2|Bacteria,3Y31N@57723|Acidobacteria	57723|Acidobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
LZS3_k127_7152907_4	156889.Mmc1_2624	1.98e-07	61.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_7152907_1	886293.Sinac_3588	1.606e-187	595.0	COG2960@1|root,COG2960@2|Bacteria,2IX5N@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
LZS3_k127_7152907_0	234267.Acid_1243	0.0	1024.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
LZS3_k127_7152907_2	1267535.KB906767_gene1220	1.612e-68	241.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
LZS3_k127_7152907_3	156889.Mmc1_2864	2.083e-24	105.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_7216874_11	234267.Acid_3817	4.123e-15	78.0	COG0583@1|root,COG0583@2|Bacteria,3Y74M@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS3_k127_7216874_14	675814.VIC_003115	2.071e-07	58.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,1T1WT@1236|Gammaproteobacteria,1XSS8@135623|Vibrionales	135623|Vibrionales	P	NAD(FAD)-dependent dehydrogenases	cdr	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
LZS3_k127_7216874_15	314345.SPV1_03143	0.0002964	44.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS3_k127_7216874_1	886293.Sinac_7090	2.337e-152	518.0	COG4692@1|root,COG4692@2|Bacteria,2J4D7@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7216874_2	1123508.JH636439_gene1088	4.148e-143	465.0	COG0111@1|root,COG0111@2|Bacteria,2IY5C@203682|Planctomycetes	203682|Planctomycetes	EH	COG0111 Phosphoglycerate dehydrogenase and related	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_7216874_10	1232410.KI421428_gene1039	1.569e-23	106.0	COG1030@1|root,COG1030@2|Bacteria,1NKSJ@1224|Proteobacteria,432IQ@68525|delta/epsilon subdivisions,2WXUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
LZS3_k127_7216874_0	1385935.N836_20045	0.0	1063.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1H7PF@1150|Oscillatoriales	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
LZS3_k127_7216874_7	323261.Noc_1288	2.026e-66	239.0	COG0589@1|root,COG0589@2|Bacteria,1MVZS@1224|Proteobacteria,1S9R4@1236|Gammaproteobacteria,1X24A@135613|Chromatiales	135613|Chromatiales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_7216874_3	525904.Tter_2668	6.687e-122	401.0	COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria	2|Bacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS3_k127_7216874_5	1123368.AUIS01000038_gene38	4.273e-73	253.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,2NCU9@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
LZS3_k127_7216874_12	234267.Acid_5861	1.039e-12	75.0	COG1734@1|root,COG1734@2|Bacteria,3Y85W@57723|Acidobacteria	57723|Acidobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS3_k127_7216874_6	985053.VMUT_1238	8.523e-68	246.0	COG4948@1|root,arCOG01168@2157|Archaea,2XPSU@28889|Crenarchaeota	28889|Crenarchaeota	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0022607,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046372,GO:0046872,GO:0047675,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:1901575	4.2.1.5,5.1.1.20,5.5.1.27	ko:K01683,ko:K18983,ko:K19802	ko00053,map00053	-	R10847,R10938	RC03287,RC03309	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_7216874_4	234267.Acid_6621	9.654e-86	299.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991,ko:K16552	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18,1.B.18.1	-	-	NTP_transf_5,Poly_export,SLBB
LZS3_k127_7216874_9	1340493.JNIF01000003_gene2912	5.722e-45	180.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,3Y7KB@57723|Acidobacteria	57723|Acidobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
LZS3_k127_7220297_6	7425.NV17660-PA	3.851e-11	77.0	KOG1230@1|root,KOG1230@2759|Eukaryota,38CJ4@33154|Opisthokonta,3BBC2@33208|Metazoa,3CZT2@33213|Bilateria,41VPY@6656|Arthropoda,3SH8Y@50557|Insecta,46HFY@7399|Hymenoptera	33208|Metazoa	S	Kelch motif	KLHDC4	-	-	-	-	-	-	-	-	-	-	-	Kelch_2,Kelch_3,Kelch_4,Kelch_5
LZS3_k127_7220297_2	1267535.KB906767_gene770	3.432e-64	226.0	COG1793@1|root,COG1793@2|Bacteria,3Y75X@57723|Acidobacteria	57723|Acidobacteria	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_7220297_5	33898.JRHJ01000069_gene7091	2.717e-12	76.0	2DK92@1|root,308WT@2|Bacteria,2GJ43@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7220297_7	1120953.AUBH01000006_gene2724	3.633e-10	71.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,1RMQZ@1236|Gammaproteobacteria,4641W@72275|Alteromonadaceae	1236|Gammaproteobacteria	QU	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
LZS3_k127_7220297_3	234267.Acid_5899	6.591e-46	191.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria	57723|Acidobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
LZS3_k127_7220297_1	469383.Cwoe_4498	3.887e-69	265.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,PA14,PATR,SLH
LZS3_k127_7254642_1	886293.Sinac_6486	1.76e-147	488.0	COG1574@1|root,COG1574@2|Bacteria,2IXY4@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_7254642_2	234267.Acid_0727	1.231e-54	198.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	yihX	GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.1.3.10,3.1.3.104,3.8.1.2	ko:K01560,ko:K07025,ko:K20866,ko:K21063	ko00010,ko00361,ko00625,ko00740,ko01100,ko01110,ko01120,map00010,map00361,map00625,map00740,map01100,map01110,map01120	M00125	R00947,R05287,R07280	RC00017,RC00078,RC00697	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
LZS3_k127_7254642_4	1382359.JIAL01000001_gene1679	3.887e-37	143.0	COG0234@1|root,COG0234@2|Bacteria,3Y4VQ@57723|Acidobacteria,2JJEF@204432|Acidobacteriia	204432|Acidobacteriia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS3_k127_7254642_5	234267.Acid_7651	7.011e-22	107.0	COG1637@1|root,COG1637@2|Bacteria,3Y5TD@57723|Acidobacteria	57723|Acidobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	NucS
LZS3_k127_7254642_0	886293.Sinac_5556	4.571e-176	565.0	COG1232@1|root,COG1232@2|Bacteria,2IYF5@203682|Planctomycetes	203682|Planctomycetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
LZS3_k127_7254642_3	1384054.N790_05510	6.561e-53	199.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,1RXYW@1236|Gammaproteobacteria,1XD03@135614|Xanthomonadales	135614|Xanthomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS3_k127_7254642_6	861299.J421_5839	1.174e-13	74.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS3_k127_7275791_1	861299.J421_1029	5.98e-145	467.0	COG3191@1|root,COG3191@2|Bacteria,1ZT47@142182|Gemmatimonadetes	2|Bacteria	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
LZS3_k127_7275791_3	319003.Bra1253DRAFT_00886	1.322e-79	273.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,3JTG8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	MA20_30275	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
LZS3_k127_7275791_2	1042326.AZNV01000032_gene5055	1.128e-142	474.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TSME@28211|Alphaproteobacteria,4BCI0@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_7275791_0	1469245.JFBG01000027_gene1512	5.23e-196	619.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RNW9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
LZS3_k127_7275791_4	652103.Rpdx1_2744	7.387e-49	185.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2TVJW@28211|Alphaproteobacteria,3JXVQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.304,1.1.1.76	ko:K18009	ko00650,map00650	-	R03707,R09078,R10505	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
LZS3_k127_7275791_5	521674.Plim_4225	9.727e-33	132.0	COG0681@1|root,COG0681@2|Bacteria,2J0ZP@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7278200_0	1125863.JAFN01000001_gene912	2.571e-301	951.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS3_k127_7278200_15	323848.Nmul_A1841	3.014e-94	327.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,2WBUD@28216|Betaproteobacteria,373TS@32003|Nitrosomonadales	28216|Betaproteobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
LZS3_k127_7278200_18	697282.Mettu_2305	7.712e-82	291.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMP5@1236|Gammaproteobacteria,1XER7@135618|Methylococcales	135618|Methylococcales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_7278200_23	187272.Mlg_2129	5.705e-52	191.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,1S4DI@1236|Gammaproteobacteria,1X0Z2@135613|Chromatiales	135613|Chromatiales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_7278200_14	234267.Acid_1833	1.633e-94	319.0	COG1136@1|root,COG1136@2|Bacteria,3Y9A0@57723|Acidobacteria	57723|Acidobacteria	V	pfam abc	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_7278200_22	330214.NIDE0349	5.765e-55	201.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	tesA	GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	iECED1_1282.ECED1_0521,iLF82_1304.LF82_2242,iNRG857_1313.NRG857_02365	Lipase_GDSL_2
LZS3_k127_7278200_10	234267.Acid_2796	6.436e-152	498.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
LZS3_k127_7278200_2	234267.Acid_3485	1.878e-245	772.0	COG0457@1|root,COG0457@2|Bacteria,3Y2M9@57723|Acidobacteria	57723|Acidobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
LZS3_k127_7278200_7	405948.SACE_4449	3.381e-153	503.0	COG4993@1|root,COG4993@2|Bacteria,2I3R4@201174|Actinobacteria,4EF6T@85010|Pseudonocardiales	201174|Actinobacteria	G	PQQ-like domain	exaA	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2,PQQ_3
LZS3_k127_7278200_40	1109445.AGSX01000083_gene3097	2.111e-06	60.0	COG2010@1|root,COG2863@1|root,COG2010@2|Bacteria,COG2863@2|Bacteria,1MW1W@1224|Proteobacteria,1SYTA@1236|Gammaproteobacteria,1Z3W0@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_7278200_39	504472.Slin_5487	4.351e-09	68.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4NHPU@976|Bacteroidetes,47KZ1@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
LZS3_k127_7278200_25	344747.PM8797T_12623	3.089e-38	158.0	COG0657@1|root,COG0657@2|Bacteria,2IXCK@203682|Planctomycetes	203682|Planctomycetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
LZS3_k127_7278200_4	1340493.JNIF01000004_gene1047	3.595e-228	725.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
LZS3_k127_7278200_3	1340493.JNIF01000004_gene1048	7.932e-238	741.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_7278200_1	234267.Acid_7437	1.575e-259	824.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,3Y79C@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
LZS3_k127_7278200_5	234267.Acid_7435	4.466e-181	577.0	COG1134@1|root,COG1134@2|Bacteria,3Y72D@57723|Acidobacteria	57723|Acidobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
LZS3_k127_7278200_16	234267.Acid_3568	1.363e-92	312.0	COG1682@1|root,COG1682@2|Bacteria	2|Bacteria	GM	macromolecule localization	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
LZS3_k127_7278200_21	234267.Acid_7775	1.102e-61	218.0	COG1595@1|root,COG1595@2|Bacteria,3Y7WY@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_7278200_8	565045.NOR51B_2570	1.998e-152	498.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1J57U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	secretory pathway	xpsE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
LZS3_k127_7278200_11	234267.Acid_7779	1.638e-144	468.0	COG1459@1|root,COG1459@2|Bacteria,3Y48Z@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
LZS3_k127_7278200_27	234267.Acid_7780	1.309e-32	131.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	gspG	-	-	ko:K02246,ko:K02456,ko:K02458	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
LZS3_k127_7278200_41	1552758.NC00_17620	0.0002242	50.0	COG4967@1|root,COG4967@2|Bacteria,1R1MP@1224|Proteobacteria,1T55P@1236|Gammaproteobacteria,1XDH1@135614|Xanthomonadales	135614|Xanthomonadales	NU	Type II secretion system (T2SS), protein I	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,T2SSI
LZS3_k127_7278200_24	234267.Acid_7784	1.211e-40	165.0	COG3156@1|root,COG3156@2|Bacteria	2|Bacteria	U	protein secretion	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
LZS3_k127_7278200_20	234267.Acid_7785	6.996e-66	244.0	COG4972@1|root,COG4972@2|Bacteria	2|Bacteria	NU	Pilus assembly protein	-	-	-	ko:K02461,ko:K02662	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	PilM_2,PilN,T2SSL
LZS3_k127_7278200_9	234267.Acid_7789	4.173e-152	516.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	gspD	-	-	ko:K02453,ko:K03219	ko03070,ko05111,map03070,map05111	M00331,M00332,M00542	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.6.1,3.A.6.3	-	-	Secretin,Secretin_N
LZS3_k127_7278200_28	234267.Acid_2463	1.149e-30	142.0	COG2133@1|root,COG2133@2|Bacteria,3Y81J@57723|Acidobacteria	57723|Acidobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_7278200_12	234267.Acid_7395	6.051e-113	373.0	COG1660@1|root,COG1660@2|Bacteria,3Y2HM@57723|Acidobacteria	57723|Acidobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
LZS3_k127_7278200_31	234267.Acid_7396	5.814e-27	118.0	COG1544@1|root,COG1544@2|Bacteria	2|Bacteria	J	regulation of translation	hpf	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808,ko:K05809	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
LZS3_k127_7278200_6	234267.Acid_7397	7.251e-166	537.0	COG1508@1|root,COG1508@2|Bacteria,3Y2M0@57723|Acidobacteria	57723|Acidobacteria	K	RNA polymerase sigma-54 factor	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
LZS3_k127_7278200_13	234267.Acid_6743	1.295e-104	346.0	COG1137@1|root,COG1137@2|Bacteria,3Y2MC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
LZS3_k127_7278200_19	234267.Acid_6744	1.005e-79	294.0	COG1452@1|root,COG1934@1|root,COG1452@2|Bacteria,COG1934@2|Bacteria,3Y388@57723|Acidobacteria	57723|Acidobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA
LZS3_k127_7278200_17	1198114.AciX9_2892	6.863e-88	319.0	COG2199@1|root,COG2203@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,3Y9F7@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
LZS3_k127_7278200_30	859657.RPSI07_2213	3.046e-29	117.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1K11Z@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
LZS3_k127_7338523_1	944564.HMPREF9200_0473	5.548e-16	85.0	COG3584@1|root,COG3584@2|Bacteria,1TTIK@1239|Firmicutes,4H320@909932|Negativicutes	909932|Negativicutes	S	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	3D,DUF348,G5
LZS3_k127_7338523_0	344747.PM8797T_27502	2.148e-137	449.0	COG4409@1|root,COG4409@2|Bacteria,2J2E2@203682|Planctomycetes	203682|Planctomycetes	G	Neuraminidase (sialidase)	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
LZS3_k127_73992_6	1379270.AUXF01000007_gene1066	2.37e-150	490.0	COG0318@1|root,COG0318@2|Bacteria,1ZUMN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_73992_16	234267.Acid_2076	3.94e-96	328.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
LZS3_k127_73992_11	234267.Acid_7066	5.298e-125	413.0	COG0673@1|root,COG0673@2|Bacteria,3Y3V4@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_73992_14	234267.Acid_1567	7.738e-116	389.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,3Y466@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
LZS3_k127_73992_9	234267.Acid_1568	2.626e-129	422.0	COG3391@1|root,COG3391@2|Bacteria,3Y99Z@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	TIG
LZS3_k127_73992_29	234267.Acid_1569	6.171e-29	124.0	COG1267@1|root,COG1267@2|Bacteria,3Y4T1@57723|Acidobacteria	57723|Acidobacteria	I	PFAM Phosphatidylglycerophosphatase A	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
LZS3_k127_73992_34	1200567.JNKD01000002_gene2203	8.536e-10	63.0	COG3024@1|root,COG3024@2|Bacteria	2|Bacteria	S	zinc ion binding	yacG	GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372	2.7.1.24	ko:K00859,ko:K09862	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	YacG
LZS3_k127_73992_2	1340493.JNIF01000003_gene3811	5.736e-170	545.0	COG0621@1|root,COG0621@2|Bacteria,3Y362@57723|Acidobacteria	57723|Acidobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
LZS3_k127_73992_10	234267.Acid_0334	3.727e-125	427.0	COG1305@1|root,COG1305@2|Bacteria,3Y5BT@57723|Acidobacteria	57723|Acidobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
LZS3_k127_73992_31	671143.DAMO_0141	5.46e-22	102.0	2EQC7@1|root,33HYA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_73992_15	1267535.KB906767_gene4409	4.495e-100	334.0	COG2159@1|root,COG2159@2|Bacteria,3Y7XT@57723|Acidobacteria,2JNXE@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_73992_24	1267535.KB906767_gene1328	9.29e-55	197.0	COG2110@1|root,COG2110@2|Bacteria,3Y4Y6@57723|Acidobacteria,2JJTQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
LZS3_k127_73992_28	1267535.KB906767_gene1735	2.504e-40	154.0	2BXJ8@1|root,342E7@2|Bacteria,3Y87K@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_73992_4	234267.Acid_4739	2.979e-163	527.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria	57723|Acidobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS3_k127_73992_25	234267.Acid_1446	3.133e-48	177.0	COG3437@1|root,COG3437@2|Bacteria,3Y907@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
LZS3_k127_73992_20	640081.Dsui_2806	6.206e-71	262.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV5M@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
LZS3_k127_73992_30	234267.Acid_1444	3.078e-25	110.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	CP_0464	-	1.8.1.9	ko:K00384,ko:K01999,ko:K07001,ko:K10914	ko00450,ko02010,ko02020,ko02024,ko02025,ko02026,ko05111,map00450,map02010,map02020,map02024,map02025,map02026,map05111	M00237	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	3.A.1.4	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_73992_21	1121007.AUML01000033_gene2786	2.382e-60	237.0	COG3202@1|root,COG3202@2|Bacteria,4NIB2@976|Bacteroidetes,1HWNK@117743|Flavobacteriia	976|Bacteroidetes	C	TLC ATP/ADP transporter	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC,cNMP_binding
LZS3_k127_73992_32	1198114.AciX9_0745	5.445e-20	97.0	COG4818@1|root,COG4818@2|Bacteria,3Y5MZ@57723|Acidobacteria,2JK19@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870,zinc_ribbon_2
LZS3_k127_73992_27	234267.Acid_2904	1.696e-41	171.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
LZS3_k127_73992_33	292563.Cyast_2360	7.232e-19	100.0	2DVYR@1|root,33XR8@2|Bacteria,1GE1F@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_73992_3	1210884.HG799462_gene8998	1.601e-164	531.0	COG0380@1|root,COG0380@2|Bacteria,2IYNH@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyltransferase family 20	-	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
LZS3_k127_73992_17	1242864.D187_007797	8.219e-79	280.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2YXK2@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS3_k127_73992_26	1267535.KB906767_gene442	1.075e-44	169.0	COG2020@1|root,COG2020@2|Bacteria,3Y4P4@57723|Acidobacteria,2JJJZ@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
LZS3_k127_73992_1	1340493.JNIF01000003_gene3892	4.725e-222	712.0	COG1452@1|root,COG1452@2|Bacteria,3Y37B@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Organic solvent tolerance protein	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
LZS3_k127_73992_5	1267535.KB906767_gene217	4.756e-157	499.0	COG3618@1|root,COG3618@2|Bacteria	2|Bacteria	H	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_73992_22	234267.Acid_6420	4.353e-59	219.0	2A6XZ@1|root,30VSX@2|Bacteria,3Y4RH@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_73992_12	234267.Acid_5841	7.786e-125	412.0	COG2265@1|root,COG2265@2|Bacteria,3Y3SF@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
LZS3_k127_73992_18	667632.KB890218_gene215	6.441e-76	259.0	COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,2VNWW@28216|Betaproteobacteria,1KHHM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
LZS3_k127_73992_19	211165.AJLN01000116_gene3204	7.947e-73	257.0	COG5486@1|root,COG5486@2|Bacteria,1GF5E@1117|Cyanobacteria	1117|Cyanobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
LZS3_k127_73992_8	926550.CLDAP_33840	4.095e-130	429.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS3_k127_73992_7	671143.DAMO_2498	4.248e-141	457.0	COG1180@1|root,COG1180@2|Bacteria,2NP82@2323|unclassified Bacteria	2|Bacteria	O	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS3_k127_73992_23	313628.LNTAR_01145	1.181e-58	216.0	COG2131@1|root,COG2131@2|Bacteria	2|Bacteria	F	dCMP deaminase activity	dcdA	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
LZS3_k127_73992_0	1123242.JH636435_gene1841	5.559e-236	754.0	COG2133@1|root,COG2133@2|Bacteria,2IYSN@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_73992_13	344747.PM8797T_18384	7.087e-123	407.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_73992_35	566461.SSFG_00032	9.853e-07	51.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria	201174|Actinobacteria	E	ornithine cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
LZS3_k127_7482027_3	192952.MM_1235	1.416e-20	96.0	COG1715@1|root,arCOG02781@2157|Archaea,2Y229@28890|Euryarchaeota,2NAA8@224756|Methanomicrobia	224756|Methanomicrobia	V	Mrr N-terminal domain	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
LZS3_k127_7482027_4	756272.Plabr_1134	6.712e-15	86.0	2FAFP@1|root,342PW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7482027_1	1121939.L861_20330	7.992e-89	301.0	COG0500@1|root,COG2226@2|Bacteria,1PH2I@1224|Proteobacteria,1S03T@1236|Gammaproteobacteria,1XRAT@135619|Oceanospirillales	135619|Oceanospirillales	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_7482027_2	62928.azo2633	5.404e-75	260.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,2VJ1P@28216|Betaproteobacteria,2KYXH@206389|Rhodocyclales	206389|Rhodocyclales	J	FtsJ-like methyltransferase	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
LZS3_k127_7486987_1	1210884.HG799464_gene11097	4.137e-92	332.0	COG2010@1|root,COG2010@2|Bacteria,2IXIX@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,PA14
LZS3_k127_7486987_0	497964.CfE428DRAFT_3923	1.486e-137	453.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,GSDH,HEAT_2,ThuA
LZS3_k127_7486987_5	2002.JOEQ01000037_gene4323	6.11e-21	108.0	COG2133@1|root,COG2133@2|Bacteria,2IB3Z@201174|Actinobacteria	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7486987_3	525904.Tter_0273	1.923e-40	163.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
LZS3_k127_7486987_4	1287276.X752_27975	3.697e-29	120.0	COG4274@1|root,COG4274@2|Bacteria,1N29P@1224|Proteobacteria,2UA3M@28211|Alphaproteobacteria,43KUA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
LZS3_k127_7486987_6	867903.ThesuDRAFT_00792	0.0002798	45.0	2DRGQ@1|root,33BNQ@2|Bacteria,1VPPR@1239|Firmicutes,24VIP@186801|Clostridia	186801|Clostridia	S	Zinc-ribbon containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451
LZS3_k127_7486987_2	1267535.KB906767_gene309	9.963e-61	221.0	2F4BE@1|root,33X1Z@2|Bacteria,3Y7SI@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_752491_4	43989.cce_4083	1.156e-83	297.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,3KHHI@43988|Cyanothece	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
LZS3_k127_752491_2	1123023.JIAI01000007_gene1965	1.902e-156	505.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,4EEMB@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
LZS3_k127_752491_0	1123277.KB893178_gene2628	4.383e-192	608.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_752491_1	204669.Acid345_3285	4.467e-174	558.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JIFD@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS3_k127_752491_7	743722.Sph21_3540	2.394e-59	208.0	COG2947@1|root,COG2947@2|Bacteria,4NNQG@976|Bacteroidetes,1ISGG@117747|Sphingobacteriia	976|Bacteroidetes	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
LZS3_k127_752491_9	321327.CYA_0604	3.02e-37	145.0	COG2371@1|root,COG2371@2|Bacteria	2|Bacteria	O	enzyme active site formation	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
LZS3_k127_752491_8	321327.CYA_0605	2.875e-45	173.0	COG0830@1|root,COG0830@2|Bacteria	2|Bacteria	O	nickel cation binding	ureF	-	3.5.1.5	ko:K01428,ko:K03188	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	UreF
LZS3_k127_752491_6	555500.I215_00025	1.351e-69	248.0	COG3622@1|root,COG3622@2|Bacteria,4NG74@976|Bacteroidetes,1HXKC@117743|Flavobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
LZS3_k127_752491_10	1267535.KB906767_gene4319	1.537e-28	119.0	COG2076@1|root,COG2076@2|Bacteria,3Y8G8@57723|Acidobacteria	57723|Acidobacteria	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_752491_11	234267.Acid_4551	2.958e-27	116.0	COG2076@1|root,COG2076@2|Bacteria,3Y93B@57723|Acidobacteria	57723|Acidobacteria	P	Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_752491_12	1380391.JIAS01000018_gene751	3.912e-25	121.0	COG3568@1|root,COG3568@2|Bacteria,1P2WU@1224|Proteobacteria,2U2FR@28211|Alphaproteobacteria,2JX7R@204441|Rhodospirillales	204441|Rhodospirillales	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_752491_3	234267.Acid_2700	7.753e-100	331.0	COG1028@1|root,COG1028@2|Bacteria,3Y6NJ@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_752491_13	1226325.HMPREF1548_00221	3.134e-23	113.0	COG4409@1|root,COG4409@2|Bacteria,1V5Q1@1239|Firmicutes,24FGZ@186801|Clostridia,36W5Z@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
LZS3_k127_752491_14	1500259.JQLD01000001_gene3752	4.739e-15	80.0	COG0582@1|root,COG0582@2|Bacteria,1RBMJ@1224|Proteobacteria,2U0ET@28211|Alphaproteobacteria,4BCUG@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
LZS3_k127_752491_5	639030.JHVA01000001_gene2752	1.418e-71	246.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria,2JKDV@204432|Acidobacteriia	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7570301_1	521674.Plim_1896	6.633e-46	173.0	COG0394@1|root,COG0394@2|Bacteria,2J115@203682|Planctomycetes	203682|Planctomycetes	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS3_k127_7570301_2	1288494.EBAPG3_13100	2.22e-33	133.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,373IX@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Regulatory protein ArsR	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
LZS3_k127_7570301_3	123899.JPQP01000023_gene3131	2.471e-29	124.0	COG0454@1|root,COG0456@2|Bacteria,1QU9D@1224|Proteobacteria,2VTPJ@28216|Betaproteobacteria,3T50V@506|Alcaligenaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_7570301_4	671143.DAMO_1089	1.871e-09	59.0	2C5EY@1|root,32YQJ@2|Bacteria,2NREI@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
LZS3_k127_7570301_0	234267.Acid_6148	2.297e-194	620.0	COG1921@1|root,COG1921@2|Bacteria,3Y6KN@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7570301_5	234267.Acid_1744	1.831e-07	55.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941,ko:K06350	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D,SLH
LZS3_k127_7575045_1	234267.Acid_7816	1.471e-202	637.0	COG1482@1|root,COG1482@2|Bacteria,3Y6FR@57723|Acidobacteria	57723|Acidobacteria	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7575045_5	204669.Acid345_4232	8.771e-87	302.0	COG0793@1|root,COG0793@2|Bacteria,3Y3A7@57723|Acidobacteria,2JHJK@204432|Acidobacteriia	204432|Acidobacteriia	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
LZS3_k127_7575045_7	1340493.JNIF01000003_gene3414	2.829e-46	180.0	COG1596@1|root,COG1596@2|Bacteria,3Y57H@57723|Acidobacteria	57723|Acidobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
LZS3_k127_7575045_3	671143.DAMO_0194	3.024e-119	411.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	ywqD	-	2.7.10.1	ko:K08252,ko:K13661,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
LZS3_k127_7575045_2	357808.RoseRS_1484	1.233e-129	423.0	COG0604@1|root,COG0604@2|Bacteria,2G6KH@200795|Chloroflexi,3763V@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_7575045_9	234267.Acid_1164	2.25e-26	116.0	COG1734@1|root,COG1734@2|Bacteria,3Y5PJ@57723|Acidobacteria	57723|Acidobacteria	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS3_k127_7575045_8	497964.CfE428DRAFT_2238	3.397e-46	175.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS3_k127_7575045_6	886293.Sinac_4639	1.144e-68	243.0	COG1082@1|root,COG1082@2|Bacteria,2IZR0@203682|Planctomycetes	2|Bacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
LZS3_k127_7575045_4	517418.Ctha_0318	4.648e-98	329.0	COG1131@1|root,COG1131@2|Bacteria,1FDTT@1090|Chlorobi	2|Bacteria	V	PFAM ABC transporter related	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
LZS3_k127_7575045_0	886293.Sinac_4981	6.46e-245	782.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,2IXSG@203682|Planctomycetes	203682|Planctomycetes	N	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_5,ABC_transp_aux
LZS3_k127_7634836_3	391616.OA238_c42550	1.318e-13	72.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2183 Transcriptional accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_7634836_0	1245469.S58_09730	0.0	1067.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1R4BB@1224|Proteobacteria,2U19X@28211|Alphaproteobacteria,3K206@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,DUF262
LZS3_k127_7634836_1	234267.Acid_4308	1.169e-73	261.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,IU_nuc_hydro
LZS3_k127_7657999_20	313596.RB2501_15129	2.475e-29	121.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes,1I37G@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
LZS3_k127_7657999_16	344747.PM8797T_12993	1.227e-46	180.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS3_k127_7657999_18	234267.Acid_6206	4.895e-44	179.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria	57723|Acidobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
LZS3_k127_7657999_9	234267.Acid_6205	1.059e-100	340.0	COG0673@1|root,COG0673@2|Bacteria,3Y3ET@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_7657999_10	234267.Acid_6204	6.597e-96	321.0	COG3494@1|root,COG3494@2|Bacteria,3Y3KI@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
LZS3_k127_7657999_8	234267.Acid_6203	3.823e-101	335.0	COG1043@1|root,COG1043@2|Bacteria,3Y33C@57723|Acidobacteria	57723|Acidobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
LZS3_k127_7657999_15	1267535.KB906767_gene3039	6.758e-50	182.0	COG0764@1|root,COG0764@2|Bacteria,3Y4CG@57723|Acidobacteria,2JJ97@204432|Acidobacteriia	204432|Acidobacteriia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
LZS3_k127_7657999_5	234267.Acid_6201	3.468e-129	422.0	COG0624@1|root,COG0624@2|Bacteria,3Y3J0@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase dimerisation domain	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS3_k127_7657999_2	234267.Acid_2984	8.964e-186	591.0	COG4948@1|root,COG4948@2|Bacteria,3Y6CG@57723|Acidobacteria	2|Bacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein	dgoD	GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034192,GO:0034194,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0071704,GO:0072329,GO:1901575	4.1.2.21,4.2.1.6	ko:K01631,ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R01064,R03033	RC00307,RC00435,RC00543	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b4478,iB21_1397.B21_03519,iBWG_1329.BWG_3382,iEC042_1314.EC042_4048,iEC55989_1330.EC55989_4161,iECBD_1354.ECBD_0011,iECB_1328.ECB_03575,iECDH10B_1368.ECDH10B_3878,iECDH1ME8569_1439.ECDH1ME8569_3579,iECD_1391.ECD_03575,iECIAI1_1343.ECIAI1_3870,iECO103_1326.ECO103_4466,iECO111_1330.ECO111_4519,iECSE_1348.ECSE_3978,iECUMN_1333.ECUMN_4223,iECW_1372.ECW_m3991,iEKO11_1354.EKO11_0011,iETEC_1333.ETEC_3982,iEcDH1_1363.EcDH1_0011,iEcE24377_1341.EcE24377A_4201,iEcSMS35_1347.EcSMS35_4057,iEcolC_1368.EcolC_0011,iJO1366.b4478,iWFL_1372.ECW_m3991,iY75_1357.Y75_RS18645	MR_MLE_C,MR_MLE_N
LZS3_k127_7657999_11	234267.Acid_2985	3.482e-91	314.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_7657999_4	1267535.KB906767_gene1681	7.886e-161	519.0	COG0399@1|root,COG0399@2|Bacteria,3Y7K8@57723|Acidobacteria,2JK8Z@204432|Acidobacteriia	57723|Acidobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_7657999_0	204669.Acid345_1995	2.828e-265	833.0	COG1185@1|root,COG1185@2|Bacteria,3Y2UG@57723|Acidobacteria,2JI5F@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
LZS3_k127_7657999_21	33905.BTHE_0528	8.549e-28	114.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4D10E@85004|Bifidobacteriales	201174|Actinobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
LZS3_k127_7657999_14	1192759.AKIB01000088_gene2323	2.432e-51	196.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
LZS3_k127_7657999_3	926550.CLDAP_28320	1.188e-167	545.0	COG0699@1|root,COG0699@2|Bacteria,2G5JQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dynamin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
LZS3_k127_7657999_6	344747.PM8797T_02644	6.205e-114	377.0	COG0530@1|root,COG0530@2|Bacteria	2|Bacteria	P	calcium, potassium:sodium antiporter activity	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS3_k127_7657999_12	658086.HMPREF0994_06084	2.258e-54	214.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Alginate_lyase,CBM_35,Glyco_hydro_127,Glyco_hydro_25,Laminin_G_3,Methyltransf_11,Prenyltrans,RHS_repeat,RicinB_lectin_2
LZS3_k127_7657999_19	234267.Acid_5912	5.48e-39	152.0	COG0824@1|root,COG0824@2|Bacteria,3Y4WZ@57723|Acidobacteria	57723|Acidobacteria	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
LZS3_k127_7657999_17	1463858.JOHR01000023_gene3989	3.198e-44	180.0	COG1680@1|root,COG1680@2|Bacteria,2GNNF@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_7657999_22	1267535.KB906767_gene1128	2.496e-05	49.0	COG2197@1|root,COG2197@2|Bacteria,3Y2WY@57723|Acidobacteria,2JIR0@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_7657999_1	1267535.KB906767_gene5003	3.662e-264	824.0	COG1574@1|root,COG1574@2|Bacteria,3Y7EK@57723|Acidobacteria	57723|Acidobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_7657999_7	886293.Sinac_2800	3.001e-103	349.0	COG4409@1|root,COG4409@2|Bacteria,2IX8T@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
LZS3_k127_7657999_13	1108045.GORHZ_084_00430	1.814e-52	202.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4GEP0@85026|Gordoniaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
LZS3_k127_7687659_4	234267.Acid_2726	9.614e-29	124.0	COG2823@1|root,COG2823@2|Bacteria,3Y7TR@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7687659_5	204669.Acid345_3555	1.095e-21	101.0	COG2823@1|root,COG2823@2|Bacteria,3Y8WE@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
LZS3_k127_7687659_2	639030.JHVA01000001_gene3279	1.523e-66	233.0	COG3861@1|root,COG3861@2|Bacteria,3Y5WZ@57723|Acidobacteria	57723|Acidobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS3_k127_7687659_6	1267535.KB906767_gene3725	2.142e-16	79.0	COG3829@1|root,COG3829@2|Bacteria,3Y2V9@57723|Acidobacteria	57723|Acidobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,PAS_9,Sigma54_activat
LZS3_k127_7687659_1	1267535.KB906767_gene3727	5.811e-108	360.0	COG2930@1|root,COG2930@2|Bacteria,3Y6Q0@57723|Acidobacteria	57723|Acidobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
LZS3_k127_7687659_7	204669.Acid345_0760	2.621e-06	59.0	COG2010@1|root,COG2010@2|Bacteria,3Y5MU@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
LZS3_k127_7687659_0	1026882.MAMP_00639	1.629e-124	411.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,1RQCM@1236|Gammaproteobacteria,462GP@72273|Thiotrichales	72273|Thiotrichales	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS3_k127_7687659_3	365528.KB891248_gene5260	1.973e-36	144.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,4ERUS@85013|Frankiales	201174|Actinobacteria	L	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
LZS3_k127_7697539_9	234267.Acid_1287	1.392e-23	102.0	COG0810@1|root,COG0810@2|Bacteria,3Y5QN@57723|Acidobacteria	57723|Acidobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS3_k127_7697539_5	485918.Cpin_6463	4.663e-88	305.0	COG1921@1|root,COG1921@2|Bacteria,4NIIG@976|Bacteroidetes,1IQ4Q@117747|Sphingobacteriia	976|Bacteroidetes	E	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
LZS3_k127_7697539_3	1340493.JNIF01000004_gene779	4.523e-100	343.0	COG1921@1|root,COG1921@2|Bacteria,3Y2SF@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
LZS3_k127_7697539_2	234267.Acid_2976	7.14e-103	344.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_7697539_4	234267.Acid_2976	1.713e-94	321.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_7697539_6	234267.Acid_3449	2.345e-60	233.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS3_k127_7697539_10	234267.Acid_5073	1.479e-23	107.0	COG1918@1|root,COG1918@2|Bacteria,3Y92B@57723|Acidobacteria	57723|Acidobacteria	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
LZS3_k127_7697539_0	234267.Acid_5074	2.266e-270	844.0	COG0370@1|root,COG0370@2|Bacteria,3Y3CZ@57723|Acidobacteria	57723|Acidobacteria	P	Ferrous iron transport protein B	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
LZS3_k127_7697539_11	324602.Caur_2011	8.577e-18	87.0	COG2308@1|root,COG2308@2|Bacteria,2GACA@200795|Chloroflexi,37575@32061|Chloroflexia	32061|Chloroflexia	S	A circularly permuted ATPgrasp	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
LZS3_k127_7697539_8	204669.Acid345_0805	1.218e-31	130.0	COG1225@1|root,COG1225@2|Bacteria,3Y8N3@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_7697539_1	886293.Sinac_6962	1.638e-237	744.0	COG3391@1|root,COG3391@2|Bacteria,2IXYJ@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7697539_7	1089547.KB913013_gene1008	8.603e-33	142.0	COG4948@1|root,COG4948@2|Bacteria,4NP0T@976|Bacteroidetes,47XKQ@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_7703392_35	289376.THEYE_A1448	2.342e-15	75.0	COG0050@1|root,COG0050@2|Bacteria,3J0DG@40117|Nitrospirae	40117|Nitrospirae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS3_k127_7703392_21	1267535.KB906767_gene2705	2.433e-52	187.0	COG0051@1|root,COG0051@2|Bacteria,3Y4V5@57723|Acidobacteria,2JJAS@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
LZS3_k127_7703392_12	1267535.KB906767_gene2704	1.819e-83	282.0	COG0087@1|root,COG0087@2|Bacteria,3Y2H7@57723|Acidobacteria,2JI91@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
LZS3_k127_7703392_14	234267.Acid_5117	1.467e-74	256.0	COG0088@1|root,COG0088@2|Bacteria,3Y2PM@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
LZS3_k127_7703392_32	1382359.JIAL01000001_gene1698	1.104e-25	109.0	COG0089@1|root,COG0089@2|Bacteria,3Y58W@57723|Acidobacteria,2JJR2@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
LZS3_k127_7703392_5	234267.Acid_5115	2.61e-139	446.0	COG0090@1|root,COG0090@2|Bacteria,3Y3DH@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
LZS3_k127_7703392_26	1144275.COCOR_03047	3.692e-40	150.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria,2YVJ3@29|Myxococcales	28221|Deltaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
LZS3_k127_7703392_29	665952.HMPREF1015_02860	4.847e-31	125.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,1ZG6U@1386|Bacillus	91061|Bacilli	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
LZS3_k127_7703392_7	1267535.KB906767_gene2698	1.415e-106	354.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria,2JIRU@204432|Acidobacteriia	204432|Acidobacteriia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
LZS3_k127_7703392_16	1267535.KB906767_gene2697	3.186e-62	217.0	COG0197@1|root,COG0197@2|Bacteria,3Y4EG@57723|Acidobacteria	57723|Acidobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
LZS3_k127_7703392_37	234267.Acid_5110	1.839e-12	70.0	COG0255@1|root,COG0255@2|Bacteria,3Y5KD@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
LZS3_k127_7703392_30	1267535.KB906767_gene2695	1.211e-29	122.0	COG0186@1|root,COG0186@2|Bacteria,3Y5I3@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
LZS3_k127_7703392_18	234267.Acid_5108	1.758e-57	201.0	COG0093@1|root,COG0093@2|Bacteria,3Y4N0@57723|Acidobacteria	57723|Acidobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
LZS3_k127_7703392_28	234267.Acid_5107	1.635e-33	133.0	COG0198@1|root,COG0198@2|Bacteria,3Y56T@57723|Acidobacteria	57723|Acidobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
LZS3_k127_7703392_13	335543.Sfum_1567	1.733e-78	268.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2MR25@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
LZS3_k127_7703392_31	1340493.JNIF01000003_gene3220	7.948e-27	113.0	COG0199@1|root,COG0199@2|Bacteria,3Y5HM@57723|Acidobacteria	57723|Acidobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
LZS3_k127_7703392_24	1340493.JNIF01000003_gene3221	5.676e-51	183.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
LZS3_k127_7703392_17	234267.Acid_5103	9.803e-61	214.0	COG0097@1|root,COG0097@2|Bacteria,3Y496@57723|Acidobacteria	57723|Acidobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
LZS3_k127_7703392_27	639030.JHVA01000001_gene1538	2.366e-38	146.0	COG0256@1|root,COG0256@2|Bacteria,3Y5CH@57723|Acidobacteria,2JJPM@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
LZS3_k127_7703392_15	240015.ACP_1434	5.354e-66	229.0	COG0098@1|root,COG0098@2|Bacteria,3Y2FE@57723|Acidobacteria,2JHKR@204432|Acidobacteriia	204432|Acidobacteriia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
LZS3_k127_7703392_38	1235799.C818_01302	6.293e-11	64.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,27PMP@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
LZS3_k127_7703392_22	1267535.KB906767_gene2686	4.794e-52	188.0	COG0200@1|root,COG0200@2|Bacteria,3Y4JC@57723|Acidobacteria,2JJ94@204432|Acidobacteriia	204432|Acidobacteriia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
LZS3_k127_7703392_4	933262.AXAM01000052_gene2009	5.499e-147	478.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2MHM9@213118|Desulfobacterales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
LZS3_k127_7703392_20	572546.Arcpr_1334	4.434e-57	207.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
LZS3_k127_7703392_6	234267.Acid_5096	1.124e-111	365.0	COG0024@1|root,COG0024@2|Bacteria,3Y2HJ@57723|Acidobacteria	57723|Acidobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
LZS3_k127_7703392_34	1382359.JIAL01000001_gene1718	2.952e-16	81.0	COG0361@1|root,COG0361@2|Bacteria,3Y55Z@57723|Acidobacteria,2JJUQ@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
LZS3_k127_7703392_36	237368.SCABRO_03483	2.486e-13	69.0	COG0257@1|root,COG0257@2|Bacteria,2J1IK@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
LZS3_k127_7703392_23	234267.Acid_5093	4.977e-52	186.0	COG0099@1|root,COG0099@2|Bacteria,3Y4KC@57723|Acidobacteria	57723|Acidobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
LZS3_k127_7703392_19	1267535.KB906767_gene2680	2.811e-57	201.0	COG0100@1|root,COG0100@2|Bacteria,3Y4BS@57723|Acidobacteria,2JJ4Q@204432|Acidobacteriia	204432|Acidobacteriia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
LZS3_k127_7703392_10	234267.Acid_5091	2.088e-90	301.0	COG0522@1|root,COG0522@2|Bacteria,3Y2I1@57723|Acidobacteria	57723|Acidobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
LZS3_k127_7703392_3	234267.Acid_5090	1.819e-155	497.0	COG0202@1|root,COG0202@2|Bacteria,3Y3HK@57723|Acidobacteria	57723|Acidobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
LZS3_k127_7703392_25	234267.Acid_5089	1.768e-50	183.0	COG0203@1|root,COG0203@2|Bacteria,3Y4JF@57723|Acidobacteria	57723|Acidobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
LZS3_k127_7703392_11	1340493.JNIF01000003_gene4811	9.685e-88	301.0	COG0760@1|root,COG0760@2|Bacteria,3Y42Z@57723|Acidobacteria	57723|Acidobacteria	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
LZS3_k127_7703392_8	204669.Acid345_2235	4.919e-98	325.0	COG0047@1|root,COG0047@2|Bacteria,3Y2YN@57723|Acidobacteria,2JIBA@204432|Acidobacteriia	204432|Acidobacteriia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
LZS3_k127_7703392_0	234267.Acid_5944	0.0	1015.0	COG0046@1|root,COG0046@2|Bacteria,3Y30N@57723|Acidobacteria	57723|Acidobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS3_k127_7703392_2	240015.ACP_1390	1.671e-180	579.0	COG0034@1|root,COG0034@2|Bacteria,3Y3RG@57723|Acidobacteria,2JHXM@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
LZS3_k127_7703392_9	1340493.JNIF01000003_gene2576	6.625e-97	339.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF11,VCBS
LZS3_k127_7703392_1	234267.Acid_1492	6.042e-266	825.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria	57723|Acidobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS3_k127_7710522_14	234267.Acid_4128	9.969e-26	115.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
LZS3_k127_7710522_13	234267.Acid_4128	2.344e-26	115.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
LZS3_k127_7710522_7	234267.Acid_1474	8.34e-88	308.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7710522_8	234267.Acid_0911	1.72e-70	255.0	COG4775@1|root,COG4775@2|Bacteria,3Y7I1@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Surface antigen variable number	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	POTRA
LZS3_k127_7710522_15	1120998.AUFC01000003_gene1376	2.423e-06	54.0	COG1551@1|root,COG1551@2|Bacteria	2|Bacteria	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
LZS3_k127_7710522_2	886293.Sinac_0668	1.452e-172	552.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_7710522_10	234267.Acid_0898	1.335e-45	168.0	COG3682@1|root,COG3682@2|Bacteria,3Y5AK@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
LZS3_k127_7710522_3	234267.Acid_0899	9.997e-159	514.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	2|Bacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
LZS3_k127_7710522_12	224911.27349067	2.344e-35	143.0	2CDHC@1|root,30KXA@2|Bacteria,1PT2N@1224|Proteobacteria,2UANN@28211|Alphaproteobacteria,3K6B4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7710522_4	234267.Acid_4958	2.236e-113	385.0	COG0265@1|root,COG0265@2|Bacteria,3Y6KE@57723|Acidobacteria	57723|Acidobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_7710522_5	1123242.JH636435_gene2052	8.62e-108	365.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
LZS3_k127_7710522_6	243090.RB5295	3.262e-100	343.0	COG3119@1|root,COG3119@2|Bacteria,2IXH3@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_7710522_9	386456.JQKN01000001_gene1834	2.089e-54	209.0	COG0124@1|root,arCOG00404@2157|Archaea,2XSYX@28890|Euryarchaeota,23NQX@183925|Methanobacteria	183925|Methanobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
LZS3_k127_7710522_11	1229909.NSED_00710	1.321e-44	171.0	COG0040@1|root,arCOG02208@2157|Archaea,41SCJ@651137|Thaumarchaeota	651137|Thaumarchaeota	E	ATP phosphoribosyltransferase	-	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
LZS3_k127_7710522_0	1123248.KB893381_gene962	1.918e-278	891.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,4P2AE@976|Bacteroidetes	976|Bacteroidetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
LZS3_k127_7710522_1	234267.Acid_4290	2.723e-202	644.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.5.1.23	ko:K12349	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00099	R01494	RC00064,RC00328	ko00000,ko00001,ko00002,ko01000	-	-	-	Ceramidase_alk,Ceramidse_alk_C
LZS3_k127_771160_4	1267535.KB906767_gene1103	6.597e-88	293.0	COG0745@1|root,COG0745@2|Bacteria	1267535.KB906767_gene1103|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_771160_0	1254432.SCE1572_25675	0.0	1455.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2YUFE@29|Myxococcales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
LZS3_k127_771160_2	344747.PM8797T_09494	3.696e-211	669.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_09690	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_771160_13	1108045.GORHZ_121_00120	0.0003006	46.0	2BT89@1|root,32NDN@2|Bacteria,2HDWZ@201174|Actinobacteria	201174|Actinobacteria	S	Ribbon-helix-helix protein, copG family	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	RHH_1
LZS3_k127_771160_12	388467.A19Y_3971	1.501e-15	81.0	COG2402@1|root,COG2402@2|Bacteria,1G6FH@1117|Cyanobacteria,1HGMI@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
LZS3_k127_771160_3	530564.Psta_2900	3.342e-194	620.0	COG3119@1|root,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2,Sulfatase
LZS3_k127_771160_7	1267535.KB906767_gene4446	8.33e-55	195.0	COG2185@1|root,COG2185@2|Bacteria,3Y4YE@57723|Acidobacteria,2JMRD@204432|Acidobacteriia	204432|Acidobacteriia	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
LZS3_k127_771160_9	234267.Acid_7487	3.265e-35	142.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
LZS3_k127_771160_11	1267533.KB906737_gene1604	1.319e-19	95.0	COG0454@1|root,COG0456@2|Bacteria,3Y5GV@57723|Acidobacteria,2JJZU@204432|Acidobacteriia	204432|Acidobacteriia	K	FR47-like protein	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
LZS3_k127_771160_1	234267.Acid_3874	1.75e-214	675.0	COG3185@1|root,COG3185@2|Bacteria,3Y2XN@57723|Acidobacteria	57723|Acidobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
LZS3_k127_771160_8	234267.Acid_5364	5.495e-43	170.0	2EGFY@1|root,30MEN@2|Bacteria,3Y7VF@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_771160_5	234267.Acid_5351	9.128e-82	281.0	COG0682@1|root,COG0682@2|Bacteria,3Y4HT@57723|Acidobacteria	57723|Acidobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS3_k127_771160_10	177437.HRM2_24900	3.996e-31	132.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria,2MK4S@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
LZS3_k127_771160_6	933262.AXAM01000068_gene2766	8.261e-56	197.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria,2MN0X@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RmlD substrate binding domain	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS3_k127_7727154_6	653733.Selin_0568	8.478e-61	225.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	mauG	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS3_k127_7727154_3	1340493.JNIF01000003_gene1469	7.056e-91	315.0	COG0760@1|root,COG0760@2|Bacteria,3Y3V9@57723|Acidobacteria	57723|Acidobacteria	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
LZS3_k127_7727154_2	234267.Acid_7419	9.908e-111	372.0	COG3481@1|root,COG3481@2|Bacteria,3Y38F@57723|Acidobacteria	57723|Acidobacteria	S	nucleic acid binding	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
LZS3_k127_7727154_8	234267.Acid_7418	8.374e-19	91.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
LZS3_k127_7727154_4	234267.Acid_5253	6.324e-88	295.0	COG0546@1|root,COG0546@2|Bacteria,3Y4RC@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS3_k127_7727154_1	234267.Acid_0749	3.113e-130	425.0	COG0476@1|root,COG0476@2|Bacteria,3Y2HZ@57723|Acidobacteria	57723|Acidobacteria	H	MoeZ MoeB domain	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
LZS3_k127_7727154_0	234267.Acid_1433	4.14e-169	541.0	COG2021@1|root,COG2021@2|Bacteria,3Y4EW@57723|Acidobacteria	57723|Acidobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
LZS3_k127_7727154_5	1123057.P872_12460	1.915e-78	282.0	28P7W@1|root,2ZC23@2|Bacteria,4NNAG@976|Bacteroidetes,47TE7@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7727154_7	234267.Acid_3219	2.325e-24	118.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria	57723|Acidobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7759497_16	1288484.APCS01000072_gene304	0.0006291	42.0	COG1494@1|root,COG1494@2|Bacteria,1WI3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
LZS3_k127_7759497_2	1254432.SCE1572_49355	7.713e-240	748.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42P6W@68525|delta/epsilon subdivisions,2WIWM@28221|Deltaproteobacteria,2YVBF@29|Myxococcales	28221|Deltaproteobacteria	L	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
LZS3_k127_7759497_14	1121085.AUCI01000012_gene2791	7.56e-23	103.0	COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
LZS3_k127_7759497_13	197221.22295959	2.282e-24	105.0	COG1669@1|root,COG1669@2|Bacteria,1G8GD@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
LZS3_k127_7759497_11	886293.Sinac_0266	3.786e-26	112.0	2ETZI@1|root,33MGP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7759497_6	479434.Sthe_2088	1.109e-90	318.0	COG0732@1|root,COG0732@2|Bacteria,2G7D0@200795|Chloroflexi	200795|Chloroflexi	L	PFAM restriction modification system DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
LZS3_k127_7759497_0	1254432.SCE1572_49335	0.0	1167.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,42MXU@68525|delta/epsilon subdivisions,2WK28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Type III restriction protein res subunit	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,Helicase_C,ResIII
LZS3_k127_7759497_10	234267.Acid_5885	5.886e-46	178.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
LZS3_k127_7759497_12	439235.Dalk_1893	1.696e-25	107.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MKKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
LZS3_k127_7759497_1	234267.Acid_1040	2.37e-261	821.0	COG1199@1|root,COG1199@2|Bacteria,3Y3DN@57723|Acidobacteria	57723|Acidobacteria	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
LZS3_k127_7759497_9	1047013.AQSP01000106_gene1773	2.342e-50	203.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
LZS3_k127_7759497_7	1210884.HG799470_gene14341	5.015e-77	264.0	COG0496@1|root,COG0496@2|Bacteria,2IZCB@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Survival protein SurE	-	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
LZS3_k127_7759497_8	935840.JAEQ01000006_gene2419	9.513e-64	235.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria	1224|Proteobacteria	K	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_7759497_5	1121904.ARBP01000040_gene530	3.594e-99	342.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,47K2H@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_7759497_4	1267535.KB906767_gene1613	3.014e-134	441.0	COG0820@1|root,COG0820@2|Bacteria,3Y3HQ@57723|Acidobacteria,2JIT9@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
LZS3_k127_7759497_3	234267.Acid_7201	5.301e-157	507.0	COG0612@1|root,COG0612@2|Bacteria,3Y3M9@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_7759497_15	257310.BB3138	1.248e-05	47.0	29ISC@1|root,2Z7VE@2|Bacteria,1MWUK@1224|Proteobacteria,2VP02@28216|Betaproteobacteria,3T6V8@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7782453_3	344747.PM8797T_30581	9.846e-28	126.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4433,MR_MLE_C
LZS3_k127_7782453_0	1267535.KB906767_gene225	1.753e-106	369.0	COG0642@1|root,COG2205@2|Bacteria,3Y4AU@57723|Acidobacteria,2JMNJ@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_7782453_1	1267535.KB906767_gene224	1.254e-99	331.0	COG0745@1|root,COG0745@2|Bacteria,3Y4D1@57723|Acidobacteria,2JMC0@204432|Acidobacteriia	204432|Acidobacteriia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_7782453_2	886293.Sinac_4401	1.248e-63	222.0	COG3871@1|root,COG3871@2|Bacteria,2J33T@203682|Planctomycetes	203682|Planctomycetes	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
LZS3_k127_7782453_4	1517682.HW49_05670	2.266e-23	101.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,2G2R6@200643|Bacteroidia	976|Bacteroidetes	G	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Big_2,FGE-sulfatase
LZS3_k127_7801095_0	234267.Acid_4251	1.645e-192	609.0	COG0001@1|root,COG0001@2|Bacteria,3Y3GA@57723|Acidobacteria	57723|Acidobacteria	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_7801095_4	204669.Acid345_1193	6.58e-49	187.0	COG1381@1|root,COG1381@2|Bacteria,3Y4AX@57723|Acidobacteria,2JJ0T@204432|Acidobacteriia	204432|Acidobacteriia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
LZS3_k127_7801095_1	1340493.JNIF01000003_gene3551	3.327e-146	468.0	COG0752@1|root,COG0752@2|Bacteria,3Y3QC@57723|Acidobacteria	57723|Acidobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
LZS3_k127_7801095_2	574087.Acear_0683	1.223e-141	477.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,3WADB@53433|Halanaerobiales	186801|Clostridia	J	glycyl-tRNA synthetase, tetrameric type, beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
LZS3_k127_7801095_3	1267535.KB906767_gene1889	4.078e-83	279.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,3Y2P5@57723|Acidobacteria,2JMA3@204432|Acidobacteriia	204432|Acidobacteriia	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS3_k127_7804260_45	661478.OP10G_1466	9.561e-08	53.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091,ko:K05967,ko:K07025	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,NT5C
LZS3_k127_7804260_36	1040989.AWZU01000008_gene3776	4.9e-34	142.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2U0D0@28211|Alphaproteobacteria,3JURI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
LZS3_k127_7804260_26	1161401.ASJA01000006_gene1974	1.63e-52	191.0	COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,2U4DJ@28211|Alphaproteobacteria,43ZRD@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS3_k127_7804260_31	350688.Clos_1093	9.673e-44	167.0	COG1595@1|root,COG1595@2|Bacteria,1V3G9@1239|Firmicutes,24G1Y@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigZ	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_7804260_34	391625.PPSIR1_13440	1.464e-37	150.0	COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,43523@68525|delta/epsilon subdivisions,2WZD3@28221|Deltaproteobacteria,2Z1VJ@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_7804260_33	304371.MCP_2802	6.194e-40	170.0	COG1404@1|root,arCOG06738@1|root,arCOG00702@2157|Archaea,arCOG06738@2157|Archaea,2XTGN@28890|Euryarchaeota,2N9WH@224756|Methanomicrobia	224756|Methanomicrobia	O	Subtilase family	-	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Calx-beta,Inhibitor_I9,Peptidase_S8
LZS3_k127_7804260_23	1142394.PSMK_09190	7.247e-61	229.0	COG3391@1|root,COG3391@2|Bacteria,2J1IA@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7804260_10	1340493.JNIF01000004_gene779	3.094e-133	436.0	COG1921@1|root,COG1921@2|Bacteria,3Y2SF@57723|Acidobacteria	57723|Acidobacteria	E	L-seryl-tRNASec selenium transferase activity	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SelA
LZS3_k127_7804260_29	62928.azo2627	1.815e-50	189.0	2FFD8@1|root,347AV@2|Bacteria,1P29K@1224|Proteobacteria,2W4JH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7804260_38	457398.HMPREF0326_00601	1.442e-30	127.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2WMCA@28221|Deltaproteobacteria,2MBVF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
LZS3_k127_7804260_4	886293.Sinac_2682	7.551e-174	558.0	COG1129@1|root,COG1129@2|Bacteria,2IXQH@203682|Planctomycetes	203682|Planctomycetes	G	transport system, ATPase	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
LZS3_k127_7804260_15	886293.Sinac_3464	8.564e-95	325.0	COG0251@1|root,COG0251@2|Bacteria,2J2W8@203682|Planctomycetes	203682|Planctomycetes	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
LZS3_k127_7804260_1	234267.Acid_1079	4.112e-236	741.0	COG1866@1|root,COG1866@2|Bacteria,3Y3U4@57723|Acidobacteria	57723|Acidobacteria	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	-	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
LZS3_k127_7804260_14	1121920.AUAU01000009_gene1896	5.695e-119	417.0	COG2183@1|root,COG2183@2|Bacteria,3Y2QM@57723|Acidobacteria	57723|Acidobacteria	K	SMART Resolvase, RNase H domain protein fold	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
LZS3_k127_7804260_25	234267.Acid_3467	3.811e-53	195.0	2F4XC@1|root,33XJD@2|Bacteria,3Y7TM@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7804260_8	234267.Acid_0353	6.363e-157	503.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS3_k127_7804260_9	234267.Acid_0352	4.223e-135	437.0	COG1071@1|root,COG1071@2|Bacteria,3Y4M3@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
LZS3_k127_7804260_3	1218352.B597_001220	2.1e-174	559.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1Z24M@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_7804260_13	396588.Tgr7_0021	4.672e-120	405.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RY0I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
LZS3_k127_7804260_47	4538.ORGLA01G0377500.1	2.454e-05	50.0	COG5126@1|root,KOG0027@2759|Eukaryota,37U1A@33090|Viridiplantae,3GI6M@35493|Streptophyta,3M50V@4447|Liliopsida,3IGUG@38820|Poales	35493|Streptophyta	T	EF-hand domain	-	GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006950,GO:0007275,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009653,GO:0009888,GO:0009987,GO:0010015,GO:0010053,GO:0010054,GO:0016049,GO:0021700,GO:0022622,GO:0030154,GO:0032501,GO:0032502,GO:0040007,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0046872,GO:0048364,GO:0048468,GO:0048469,GO:0048588,GO:0048589,GO:0048731,GO:0048764,GO:0048765,GO:0048767,GO:0048856,GO:0048869,GO:0050896,GO:0060560,GO:0071695,GO:0080147,GO:0090558,GO:0090627,GO:0099402,GO:1905392	-	ko:K13448	ko04626,map04626	-	-	-	ko00000,ko00001	-	-	-	EF-hand_1,EF-hand_5,EF-hand_7
LZS3_k127_7804260_43	1333856.L686_01885	3.357e-10	66.0	2EG5Q@1|root,339XK@2|Bacteria,1NGQ6@1224|Proteobacteria,1SHCX@1236|Gammaproteobacteria,1Z2SI@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4168)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4168
LZS3_k127_7804260_44	28258.KP05_07925	3.912e-09	64.0	2EG5Q@1|root,339XK@2|Bacteria,1NGQ6@1224|Proteobacteria,1SHCX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4168)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4168
LZS3_k127_7804260_41	234267.Acid_7418	1.362e-17	88.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
LZS3_k127_7804260_12	234267.Acid_5783	1.137e-130	439.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS3_k127_7804260_20	383372.Rcas_3850	3.444e-78	282.0	COG2133@1|root,COG2133@2|Bacteria,2G90Z@200795|Chloroflexi	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
LZS3_k127_7804260_6	547163.BN979_05053	7.014e-163	520.0	COG1409@1|root,COG1409@2|Bacteria,2I95A@201174|Actinobacteria,2377P@1762|Mycobacteriaceae	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_7804260_21	243233.MCA0358	2.308e-77	263.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XE6B@135618|Methylococcales	135618|Methylococcales	L	PFAM Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
LZS3_k127_7804260_28	1340493.JNIF01000003_gene2266	1.085e-51	186.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,Cupin_7,HTH_18
LZS3_k127_7804260_30	234267.Acid_0525	1.087e-49	186.0	COG4798@1|root,COG4798@2|Bacteria	2|Bacteria	E	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FAD_binding_4,Methyltransf_11,Methyltransf_25,Methyltransf_31,SAM_MT
LZS3_k127_7804260_18	1267535.KB906767_gene307	1.915e-86	295.0	COG0684@1|root,COG0684@2|Bacteria,3Y3TT@57723|Acidobacteria	57723|Acidobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
LZS3_k127_7804260_17	472759.Nhal_2554	2.99e-88	305.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WWAK@135613|Chromatiales	135613|Chromatiales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
LZS3_k127_7804260_2	1005058.UMN179_01107	1.874e-188	597.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1Y7ED@135625|Pasteurellales	135625|Pasteurellales	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	-	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
LZS3_k127_7804260_16	1121918.ARWE01000001_gene1330	2.213e-92	307.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria	1224|Proteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
LZS3_k127_7804260_19	1121918.ARWE01000001_gene1329	3.603e-82	279.0	COG1347@1|root,COG1347@2|Bacteria,1R343@1224|Proteobacteria	1224|Proteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	-	-	-	-	-	-	-	-	-	-	-	-	Rnf-Nqr
LZS3_k127_7804260_22	1323663.AROI01000009_gene3601	4.311e-71	249.0	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
LZS3_k127_7804260_7	1353529.M899_2370	1.232e-157	507.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,42MTU@68525|delta/epsilon subdivisions,2WKN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	-	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
LZS3_k127_7804260_5	391625.PPSIR1_12063	5.689e-170	544.0	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,42PMT@68525|delta/epsilon subdivisions,2WK84@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_10,NQRA,NQRA_SLBB
LZS3_k127_7804260_42	398767.Glov_0035	1.309e-10	65.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2WSM2@28221|Deltaproteobacteria,43VNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS3_k127_7804260_27	234267.Acid_1430	2.424e-52	189.0	COG0789@1|root,COG0789@2|Bacteria,3Y5EZ@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
LZS3_k127_7804260_32	234267.Acid_0043	2.948e-41	163.0	COG2834@1|root,COG2834@2|Bacteria,3Y4XE@57723|Acidobacteria	57723|Acidobacteria	M	outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
LZS3_k127_7804260_11	234267.Acid_0044	8.791e-131	429.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria	57723|Acidobacteria	NU	type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
LZS3_k127_7804260_0	1340493.JNIF01000003_gene1704	3.185e-261	813.0	COG2804@1|root,COG2804@2|Bacteria,3Y3GB@57723|Acidobacteria	57723|Acidobacteria	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
LZS3_k127_7804260_24	234267.Acid_0046	1.561e-60	222.0	COG4972@1|root,COG4972@2|Bacteria,3Y4X3@57723|Acidobacteria	57723|Acidobacteria	NU	Pilus assembly protein	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	-
LZS3_k127_7804260_37	1340493.JNIF01000003_gene1706	7.998e-31	128.0	COG3166@1|root,COG3166@2|Bacteria,3Y4GJ@57723|Acidobacteria	57723|Acidobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
LZS3_k127_7804260_39	234267.Acid_0049	3.23e-29	127.0	2C8FF@1|root,333TN@2|Bacteria,3Y5GA@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7804260_35	234267.Acid_0050	1.571e-35	155.0	2DRPK@1|root,32URD@2|Bacteria,3Y4UQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7810876_0	886293.Sinac_5109	9.471e-274	863.0	COG2010@1|root,COG2010@2|Bacteria,2IXIG@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
LZS3_k127_7810876_4	671143.DAMO_0998	9.676e-21	99.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS3_k127_7810876_2	138119.DSY0993	6.08e-60	217.0	COG1145@1|root,COG1145@2|Bacteria,1UIDU@1239|Firmicutes,25EIV@186801|Clostridia,267A7@186807|Peptococcaceae	186801|Clostridia	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7810876_3	401526.TcarDRAFT_2289	1.211e-37	150.0	2AV93@1|root,31M00@2|Bacteria,1V94N@1239|Firmicutes,4H7KF@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7810876_1	1123242.JH636434_gene3903	2.052e-75	254.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7821310_4	234267.Acid_5675	2.23e-139	450.0	COG0535@1|root,COG0535@2|Bacteria,3Y3QA@57723|Acidobacteria	57723|Acidobacteria	S	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS3_k127_7821310_3	234267.Acid_7333	1.011e-161	520.0	COG0128@1|root,COG0128@2|Bacteria,3Y3RH@57723|Acidobacteria	57723|Acidobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
LZS3_k127_7821310_5	1267535.KB906767_gene424	2.167e-37	145.0	COG0494@1|root,COG0494@2|Bacteria,3Y55X@57723|Acidobacteria	57723|Acidobacteria	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
LZS3_k127_7821310_0	234267.Acid_5890	1.802e-271	850.0	COG0018@1|root,COG0018@2|Bacteria,3Y35R@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
LZS3_k127_7821310_2	1267535.KB906767_gene1145	2.825e-172	553.0	COG0008@1|root,COG0008@2|Bacteria,3Y465@57723|Acidobacteria,2JHZW@204432|Acidobacteriia	204432|Acidobacteriia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
LZS3_k127_7821310_1	234267.Acid_5013	2.024e-200	639.0	COG2192@1|root,COG2192@2|Bacteria,3Y6AX@57723|Acidobacteria	57723|Acidobacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
LZS3_k127_7821310_7	794903.OPIT5_30725	0.0002427	46.0	2DN84@1|root,32W19@2|Bacteria,46W13@74201|Verrucomicrobia,3K9NJ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7823251_0	1340493.JNIF01000004_gene907	1.162e-300	937.0	COG3808@1|root,COG3808@2|Bacteria,3Y34E@57723|Acidobacteria	57723|Acidobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
LZS3_k127_7823251_9	909663.KI867149_gene3387	8.153e-74	256.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MR44@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
LZS3_k127_7823251_2	247490.KSU1_C1626	5.833e-225	713.0	COG1966@1|root,COG1966@2|Bacteria,2IWZE@203682|Planctomycetes	203682|Planctomycetes	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
LZS3_k127_7823251_5	1379698.RBG1_1C00001G0467	1.207e-117	388.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
LZS3_k127_7823251_6	518766.Rmar_0956	6.668e-113	383.0	COG1301@1|root,COG1301@2|Bacteria,4NDUU@976|Bacteroidetes,1FIV5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	-	-	-	-	-	-	-	-	-	SDF
LZS3_k127_7823251_4	1336208.JADY01000002_gene508	1.442e-167	540.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2JUR5@204441|Rhodospirillales	204441|Rhodospirillales	E	C-terminus of AA_permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
LZS3_k127_7823251_8	1267535.KB906767_gene4739	7.854e-98	336.0	COG0341@1|root,COG0341@2|Bacteria,3Y2ZT@57723|Acidobacteria,2JHZF@204432|Acidobacteriia	204432|Acidobacteriia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS3_k127_7823251_1	502025.Hoch_2359	4.788e-258	830.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_7823251_12	156889.Mmc1_2624	1.054e-22	99.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
LZS3_k127_7823251_11	204669.Acid345_4558	1.094e-35	156.0	COG3710@1|root,COG3710@2|Bacteria,3Y7KB@57723|Acidobacteria,2JMW2@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
LZS3_k127_7823251_7	234267.Acid_5749	5.473e-109	380.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
LZS3_k127_7823251_10	401053.AciPR4_2718	1.69e-42	162.0	COG3710@1|root,COG3710@2|Bacteria,3Y7KB@57723|Acidobacteria,2JMW2@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
LZS3_k127_7823251_3	743299.Acife_2323	1.776e-193	613.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
LZS3_k127_7823251_14	794903.OPIT5_18145	6.527e-14	74.0	COG3385@1|root,COG3385@2|Bacteria,46Y03@74201|Verrucomicrobia,3K8Q3@414999|Opitutae	414999|Opitutae	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
LZS3_k127_7833014_4	1267535.KB906767_gene856	2.802e-110	372.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_7833014_1	234267.Acid_5840	2.183e-144	467.0	COG0180@1|root,COG0180@2|Bacteria,3Y2VN@57723|Acidobacteria	57723|Acidobacteria	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS3_k127_7833014_3	234267.Acid_7235	3.573e-120	396.0	COG0583@1|root,COG0583@2|Bacteria,3Y4EH@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS3_k127_7833014_6	1267535.KB906767_gene1312	1.548e-08	62.0	297GA@1|root,2ZUPK@2|Bacteria,3Y8WK@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7833014_2	234267.Acid_5138	1.475e-126	419.0	COG4198@1|root,COG4198@2|Bacteria,3Y2H9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised conserved protein UCP033563	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
LZS3_k127_7833014_5	1500893.JQNB01000001_gene1609	3.719e-44	165.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1SBBF@1236|Gammaproteobacteria,1XDAF@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_7833014_0	1267535.KB906767_gene67	1.266e-150	490.0	COG1007@1|root,COG1007@2|Bacteria,3Y3PV@57723|Acidobacteria,2JIT3@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
LZS3_k127_7833014_7	1267535.KB906767_gene66	0.0002999	44.0	COG1008@1|root,COG1008@2|Bacteria,3Y3VX@57723|Acidobacteria	2|Bacteria	C	Proton-conducting membrane transporter	nuoM	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iSDY_1059.SDY_2473	Proton_antipo_M
LZS3_k127_7846282_0	234267.Acid_1167	9.817e-203	637.0	COG0304@1|root,COG0304@2|Bacteria,3Y3IS@57723|Acidobacteria	57723|Acidobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_7846282_3	234267.Acid_1168	3.048e-25	106.0	COG0236@1|root,COG0236@2|Bacteria,3Y54V@57723|Acidobacteria	57723|Acidobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS3_k127_7846282_2	1340493.JNIF01000003_gene1795	2.814e-75	258.0	COG1974@1|root,COG1974@2|Bacteria,3Y47Z@57723|Acidobacteria	57723|Acidobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
LZS3_k127_7846282_1	1267534.KB906756_gene415	1.084e-82	282.0	COG1738@1|root,COG1738@2|Bacteria,3Y35H@57723|Acidobacteria,2JIRA@204432|Acidobacteriia	204432|Acidobacteriia	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
LZS3_k127_786351_5	234267.Acid_2565	1.234e-24	109.0	COG0164@1|root,COG0164@2|Bacteria,3Y49K@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS3_k127_786351_2	1267535.KB906767_gene3059	5.346e-40	152.0	COG0335@1|root,COG0335@2|Bacteria,3Y4P6@57723|Acidobacteria,2JJ9V@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
LZS3_k127_786351_1	234267.Acid_2569	3.218e-88	298.0	COG0336@1|root,COG0336@2|Bacteria,3Y3CS@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
LZS3_k127_786351_3	234267.Acid_2570	1.506e-35	145.0	COG0806@1|root,COG0806@2|Bacteria	2|Bacteria	J	ribosome binding	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
LZS3_k127_786351_4	234267.Acid_2571	7.3e-26	109.0	COG1837@1|root,COG1837@2|Bacteria,3Y5N5@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
LZS3_k127_786351_6	1267535.KB906767_gene3055	4.823e-24	107.0	COG0228@1|root,COG0228@2|Bacteria,3Y56G@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
LZS3_k127_786351_0	644966.Tmar_0957	9.534e-156	503.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WCDI@538999|Clostridiales incertae sedis	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
LZS3_k127_7866708_9	1267535.KB906767_gene3453	1.271e-76	273.0	COG0673@1|root,COG0673@2|Bacteria,3Y4RG@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_7866708_0	518766.Rmar_1775	4.619e-225	711.0	COG0457@1|root,COG0457@2|Bacteria,4NFIY@976|Bacteroidetes	976|Bacteroidetes	S	Peptidase, family M49	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M49
LZS3_k127_7866708_1	1173024.KI912154_gene1184	1.248e-214	674.0	arCOG06766@1|root,2Z87F@2|Bacteria,1G1NX@1117|Cyanobacteria,1JKSG@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7866708_3	314278.NB231_07462	1.104e-158	508.0	COG2230@1|root,COG2230@2|Bacteria,1QY55@1224|Proteobacteria,1RYEN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS3_k127_7866708_6	1267535.KB906767_gene230	1.085e-123	422.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Peptidase_S9
LZS3_k127_7866708_2	234267.Acid_2187	3.398e-159	512.0	COG0019@1|root,COG0019@2|Bacteria,3Y2W4@57723|Acidobacteria	57723|Acidobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
LZS3_k127_7866708_4	234267.Acid_2206	1.322e-154	507.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria	57723|Acidobacteria	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
LZS3_k127_7866708_10	391623.TERMP_01541	1.98e-68	242.0	COG0274@1|root,arCOG04320@2157|Archaea,2XT2D@28890|Euryarchaeota,242NJ@183968|Thermococci	183968|Thermococci	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
LZS3_k127_7866708_12	1267535.KB906767_gene3378	7.733e-38	147.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS3_k127_7866708_11	886293.Sinac_6370	2.322e-57	217.0	COG2960@1|root,COG2960@2|Bacteria,2IX87@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
LZS3_k127_7866708_7	906968.Trebr_2147	8.726e-105	350.0	COG0530@1|root,COG0530@2|Bacteria,2J885@203691|Spirochaetes	203691|Spirochaetes	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS3_k127_7866708_5	794903.OPIT5_15790	8.798e-139	453.0	COG2271@1|root,COG2271@2|Bacteria,46UQA@74201|Verrucomicrobia,3K8MQ@414999|Opitutae	414999|Opitutae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_7866708_8	1410619.SRDD_26560	8.748e-79	279.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,400MR@613|Serratia	1236|Gammaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_7899339_0	1380600.AUYN01000001_gene2799	1.921e-245	784.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,1HY2S@117743|Flavobacteriia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
LZS3_k127_7899339_7	234267.Acid_2600	3.133e-126	411.0	COG2404@1|root,COG2404@2|Bacteria,3Y98M@57723|Acidobacteria	57723|Acidobacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7899339_18	596152.DesU5LDRAFT_0117	6.211e-14	83.0	COG1639@1|root,COG1639@2|Bacteria,1Q5XJ@1224|Proteobacteria,4320Z@68525|delta/epsilon subdivisions,2WWF5@28221|Deltaproteobacteria,2MA1H@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
LZS3_k127_7899339_16	443144.GM21_1909	1.327e-30	126.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,42RSE@68525|delta/epsilon subdivisions,2WP0K@28221|Deltaproteobacteria,43SGX@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
LZS3_k127_7899339_3	1382359.JIAL01000001_gene1629	2.195e-204	644.0	COG0439@1|root,COG0439@2|Bacteria,3Y2QZ@57723|Acidobacteria,2JIFS@204432|Acidobacteriia	204432|Acidobacteriia	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS3_k127_7899339_14	204669.Acid345_3288	3.916e-37	147.0	COG0511@1|root,COG0511@2|Bacteria,3Y4W8@57723|Acidobacteria,2JJHQ@204432|Acidobacteriia	204432|Acidobacteriia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
LZS3_k127_7899339_10	1267535.KB906767_gene4315	8.807e-95	326.0	COG0006@1|root,COG0006@2|Bacteria,3Y3IN@57723|Acidobacteria,2JI8R@204432|Acidobacteriia	204432|Acidobacteriia	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
LZS3_k127_7899339_22	204669.Acid345_1473	0.0001534	52.0	COG4796@1|root,COG4796@2|Bacteria,3Y98D@57723|Acidobacteria	57723|Acidobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
LZS3_k127_7899339_15	204669.Acid345_1469	1.253e-32	140.0	COG4972@1|root,COG4972@2|Bacteria,3Y804@57723|Acidobacteria	57723|Acidobacteria	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
LZS3_k127_7899339_6	1340493.JNIF01000003_gene1919	3.098e-130	438.0	COG5000@1|root,COG5000@2|Bacteria,3Y32Z@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_7899339_4	1267535.KB906767_gene838	1.149e-195	619.0	COG2204@1|root,COG2204@2|Bacteria,3Y3HH@57723|Acidobacteria,2JI5D@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_7899339_17	234267.Acid_4795	6.56e-22	104.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria	57723|Acidobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
LZS3_k127_7899339_20	251221.35211983	1.872e-11	67.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_7899339_5	1183438.GKIL_2517	6.387e-133	436.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS3_k127_7899339_8	234267.Acid_6481	3.005e-110	361.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria	57723|Acidobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_7899339_1	330214.NIDE2536	7.075e-238	750.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
LZS3_k127_7899339_9	1157708.KB907450_gene5746	1.664e-105	362.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2VRGQ@28216|Betaproteobacteria,4ADHS@80864|Comamonadaceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_7899339_11	880070.Cycma_1900	3.81e-91	314.0	COG3616@1|root,COG3616@2|Bacteria	2|Bacteria	E	Alanine racemase, N-terminal domain	dhaa	-	4.1.2.42,4.1.3.41	ko:K18425,ko:K19967	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
LZS3_k127_7899339_19	234267.Acid_0137	6.159e-13	76.0	COG1595@1|root,COG1595@2|Bacteria,3Y5ME@57723|Acidobacteria	57723|Acidobacteria	K	region 4 type 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_7899339_13	1340493.JNIF01000004_gene597	1.541e-61	243.0	COG1629@1|root,COG1629@2|Bacteria,3Y6Z5@57723|Acidobacteria	57723|Acidobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_7899339_12	1121324.CLIT_5c00690	5.353e-69	251.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia	186801|Clostridia	P	Transporter, CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
LZS3_k127_7899339_2	1267535.KB906767_gene409	1.372e-237	749.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_79254_3	639030.JHVA01000001_gene2752	2.346e-139	459.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria,2JKDV@204432|Acidobacteriia	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_79254_0	234267.Acid_1034	2.802e-204	648.0	COG1190@1|root,COG1190@2|Bacteria,3Y3N0@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS3_k127_79254_5	204669.Acid345_3567	9.604e-120	400.0	COG4591@1|root,COG4591@2|Bacteria,3Y3BU@57723|Acidobacteria,2JIC6@204432|Acidobacteriia	204432|Acidobacteriia	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
LZS3_k127_79254_1	1267535.KB906767_gene844	2.744e-160	520.0	COG0260@1|root,COG0260@2|Bacteria,3Y33T@57723|Acidobacteria,2JHUM@204432|Acidobacteriia	204432|Acidobacteriia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
LZS3_k127_79254_14	671143.DAMO_0839	5.988e-12	67.0	COG1662@1|root,COG1662@2|Bacteria	2|Bacteria	L	PFAM IS1 transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1,DDE_Tnp_IS240
LZS3_k127_79254_16	1127131.WEISSC39_08045	0.0007129	51.0	2A4M6@1|root,30T7Z@2|Bacteria,1VZFV@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_79254_6	234267.Acid_2848	1.517e-113	377.0	COG1044@1|root,COG1044@2|Bacteria,3Y6ZT@57723|Acidobacteria	57723|Acidobacteria	M	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD	-	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
LZS3_k127_79254_11	278963.ATWD01000001_gene4021	9.355e-61	219.0	2E19M@1|root,2ZCDB@2|Bacteria,3Y4DH@57723|Acidobacteria,2JJ2T@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_79254_7	234267.Acid_6299	2.107e-100	334.0	COG0130@1|root,COG0130@2|Bacteria,3Y3PG@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
LZS3_k127_79254_12	234267.Acid_0131	1.431e-52	202.0	COG3103@1|root,COG3103@2|Bacteria,3Y3S0@57723|Acidobacteria	57723|Acidobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_8
LZS3_k127_79254_10	745411.B3C1_16009	1.541e-81	284.0	COG1808@1|root,COG1808@2|Bacteria,1NMS3@1224|Proteobacteria,1RRTC@1236|Gammaproteobacteria,1J6Z7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
LZS3_k127_79254_8	760192.Halhy_2614	3.161e-98	338.0	COG0591@1|root,COG0591@2|Bacteria,4NH7H@976|Bacteroidetes,1IZ8B@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14387	ko04725,ko05231,map04725,map05231	-	-	-	ko00000,ko00001,ko02000	2.A.21,2.A.21.8	-	-	HD_4,SSF
LZS3_k127_79254_2	234267.Acid_5202	9.269e-145	473.0	COG0407@1|root,COG0407@2|Bacteria,3Y44R@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
LZS3_k127_79254_13	420246.GTNG_0706	1.437e-40	160.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,1WFBZ@129337|Geobacillus	91061|Bacilli	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
LZS3_k127_79254_4	204669.Acid345_1153	4.027e-121	413.0	COG0860@1|root,COG0860@2|Bacteria,3Y3M0@57723|Acidobacteria,2JI9V@204432|Acidobacteriia	204432|Acidobacteriia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
LZS3_k127_79254_9	234267.Acid_3783	1.98e-97	337.0	COG5010@1|root,COG5010@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K13486	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Acetyltransf_6,DUF1570,Response_reg,TPR_16,TPR_19
LZS3_k127_79601_0	237368.SCABRO_03044	5.231e-114	385.0	COG2204@1|root,COG2204@2|Bacteria,2IXIQ@203682|Planctomycetes	203682|Planctomycetes	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_79601_1	1123508.JH636442_gene4015	3.709e-106	358.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_79601_2	756272.Plabr_2748	1.857e-47	175.0	COG0251@1|root,COG0251@2|Bacteria,2J34Z@203682|Planctomycetes	203682|Planctomycetes	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
LZS3_k127_79601_3	1341151.ASZU01000003_gene2458	7.58e-40	168.0	28M6Z@1|root,2ZAKH@2|Bacteria,1VFV5@1239|Firmicutes,4HWVX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7966178_0	1123393.KB891316_gene2018	1.018e-148	480.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7966178_1	1521187.JPIM01000188_gene1946	2.096e-105	376.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi,3767C@32061|Chloroflexia	32061|Chloroflexia	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7966178_3	234267.Acid_4062	1.268e-27	131.0	COG3391@1|root,COG4447@1|root,COG3391@2|Bacteria,COG4447@2|Bacteria,3Y31A@57723|Acidobacteria	57723|Acidobacteria	U	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7966178_4	575540.Isop_0175	7.998e-13	82.0	COG1807@1|root,COG1807@2|Bacteria,2J1QR@203682|Planctomycetes	203682|Planctomycetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7966178_2	1183438.GKIL_3999	4.822e-34	137.0	COG1216@1|root,COG1216@2|Bacteria,1G2W7@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_8004697_14	439235.Dalk_1318	1.29e-35	141.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,43BHF@68525|delta/epsilon subdivisions,2WQUJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
LZS3_k127_8004697_15	1232437.KL661991_gene494	1.17e-14	75.0	2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria,42XZU@68525|delta/epsilon subdivisions,2WX7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8004697_11	1340493.JNIF01000003_gene4181	6.763e-73	257.0	COG1879@1|root,COG1879@2|Bacteria,3Y872@57723|Acidobacteria	57723|Acidobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
LZS3_k127_8004697_7	1340493.JNIF01000003_gene4181	1.249e-103	347.0	COG1879@1|root,COG1879@2|Bacteria,3Y872@57723|Acidobacteria	57723|Acidobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
LZS3_k127_8004697_9	1499967.BAYZ01000194_gene3127	1.041e-74	258.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	ywhC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
LZS3_k127_8004697_12	1267535.KB906767_gene2483	1.854e-60	219.0	COG1028@1|root,COG1028@2|Bacteria,3Y822@57723|Acidobacteria	57723|Acidobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_8004697_1	1267535.KB906767_gene3394	8.881e-255	796.0	COG0129@1|root,COG0129@2|Bacteria,3Y372@57723|Acidobacteria,2JIK1@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
LZS3_k127_8004697_3	342113.DM82_3811	5.346e-210	664.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VHC1@28216|Betaproteobacteria,1K09M@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.16.1.1	ko:K00520,ko:K21739	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS3_k127_8004697_13	1005048.CFU_2569	1.674e-59	210.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,2VTKP@28216|Betaproteobacteria,474QB@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
LZS3_k127_8004697_0	497964.CfE428DRAFT_5426	4.104e-267	838.0	COG1680@1|root,COG1680@2|Bacteria,46WGY@74201|Verrucomicrobia	74201|Verrucomicrobia	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8004697_17	396588.Tgr7_1929	6.063e-09	62.0	COG3011@1|root,COG3011@2|Bacteria,1PV30@1224|Proteobacteria,1SCCX@1236|Gammaproteobacteria,1WZJ7@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
LZS3_k127_8004697_8	234267.Acid_2380	3.113e-101	347.0	COG2133@1|root,COG3292@1|root,COG2133@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHB_HEX_C_1,DUF1906,Glyco_hydro_18,Malectin,PA14,SLH,VCBS
LZS3_k127_8004697_4	234267.Acid_7026	5.265e-186	610.0	COG1629@1|root,COG3485@1|root,COG3485@2|Bacteria,COG4771@2|Bacteria,3Y7F9@57723|Acidobacteria	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8004697_5	1267535.KB906767_gene765	5.199e-180	573.0	COG2960@1|root,COG2960@2|Bacteria,3Y7EA@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
LZS3_k127_8004697_2	1267535.KB906767_gene766	1.632e-229	736.0	COG0551@1|root,COG0551@2|Bacteria,3Y7FR@57723|Acidobacteria	57723|Acidobacteria	L	Protein of unknown function (DUF1595)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
LZS3_k127_8004697_6	234267.Acid_1848	1.975e-167	538.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_8004697_10	1267535.KB906767_gene409	5.509e-74	254.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_8015692_6	1267535.KB906767_gene265	1.392e-29	119.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	hscA	-	-	-	-	-	-	-	-	-	-	-	HSP70,RNase_Zc3h12a
LZS3_k127_8015692_2	234267.Acid_6728	2.39e-167	535.0	COG1914@1|root,COG1914@2|Bacteria,3Y3EU@57723|Acidobacteria	57723|Acidobacteria	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
LZS3_k127_8015692_3	234267.Acid_6727	5.121e-140	456.0	COG2239@1|root,COG2239@2|Bacteria,3Y3WD@57723|Acidobacteria	57723|Acidobacteria	P	MgtE intracellular	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
LZS3_k127_8015692_4	1123242.JH636434_gene5244	1.648e-62	237.0	2E55N@1|root,32ZYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8015692_1	1340493.JNIF01000003_gene3118	1.626e-216	714.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,Plug,TonB_dep_Rec
LZS3_k127_8015692_5	1123242.JH636434_gene5244	3.206e-62	237.0	2E55N@1|root,32ZYI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8015692_8	3712.Bo3g183920.1	7.832e-07	62.0	COG0457@1|root,COG0526@1|root,KOG0907@2759|Eukaryota,KOG1124@2759|Eukaryota,37NEJ@33090|Viridiplantae,3GAW4@35493|Streptophyta,3HN9U@3699|Brassicales	35493|Streptophyta	O	TPR repeat-containing thioredoxin	-	GO:0001101,GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0009651,GO:0009719,GO:0009725,GO:0009737,GO:0009787,GO:0009789,GO:0009966,GO:0009967,GO:0010033,GO:0010646,GO:0010647,GO:0023051,GO:0023056,GO:0033993,GO:0042221,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0097305,GO:1901419,GO:1901421,GO:1901700,GO:1905957,GO:1905959	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Thioredoxin
LZS3_k127_8015692_0	1340493.JNIF01000003_gene3118	6.353e-228	747.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,Plug,TonB_dep_Rec
LZS3_k127_8015692_7	278963.ATWD01000002_gene260	6.438e-19	91.0	COG1629@1|root,COG4771@2|Bacteria,3Y3KD@57723|Acidobacteria,2JIB2@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
LZS3_k127_8023760_3	234267.Acid_6383	2.311e-86	297.0	COG0859@1|root,COG0859@2|Bacteria,3Y3EJ@57723|Acidobacteria	57723|Acidobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_8023760_7	1123073.KB899241_gene2627	7.109e-56	209.0	COG2755@1|root,COG2755@2|Bacteria,1RE9P@1224|Proteobacteria,1SF9P@1236|Gammaproteobacteria,1X5EE@135614|Xanthomonadales	135614|Xanthomonadales	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS3_k127_8023760_1	204669.Acid345_2676	9.807e-148	484.0	COG0793@1|root,COG0793@2|Bacteria,3Y3KP@57723|Acidobacteria,2JHNE@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
LZS3_k127_8023760_5	240015.ACP_0955	1.227e-73	258.0	COG0842@1|root,COG0842@2|Bacteria,3Y2S4@57723|Acidobacteria,2JISC@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
LZS3_k127_8023760_0	458817.Shal_2420	4.822e-167	542.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,2QAXB@267890|Shewanellaceae	1236|Gammaproteobacteria	M	TIGRFAM gamma-glutamyltransferase	ggt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	iAPECO1_1312.APECO1_3012,iECOK1_1307.ECOK1_3869,iECS88_1305.ECS88_3844,iECW_1372.ECW_m3706,iEKO11_1354.EKO11_0296,iETEC_1333.ETEC_3693,iUMN146_1321.UM146_17325,iUTI89_1310.UTI89_C3954,iWFL_1372.ECW_m3706	G_glu_transpept
LZS3_k127_8023760_8	1397693.KK211187_gene1034	6.197e-45	171.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli,3WEHW@539002|Bacillales incertae sedis	91061|Bacilli	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
LZS3_k127_8023760_2	460265.Mnod_2965	1.914e-136	441.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TUT7@28211|Alphaproteobacteria,1JSXA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM 2-nitropropane dioxygenase NPD	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
LZS3_k127_8023760_9	398579.Spea_3677	7.476e-07	62.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
LZS3_k127_8023760_4	316067.Geob_2204	4.262e-83	286.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,42NDF@68525|delta/epsilon subdivisions,2WJPS@28221|Deltaproteobacteria,43TE5@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
LZS3_k127_8023760_6	234267.Acid_4604	1.958e-60	237.0	COG1470@1|root,COG3291@1|root,COG1470@2|Bacteria,COG3291@2|Bacteria,3Y97Z@57723|Acidobacteria	57723|Acidobacteria	G	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
LZS3_k127_803643_20	1304275.C41B8_16659	0.0004217	42.0	COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria	1224|Proteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabF1	-	-	ko:K14660	-	-	-	-	ko00000,ko01000	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_803643_3	1122605.KB893637_gene3269	1.226e-178	593.0	COG4692@1|root,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,DUF3604,F5_F8_type_C,FIVAR
LZS3_k127_803643_7	935567.JAES01000001_gene2175	1.932e-89	306.0	COG3751@1|root,COG3751@2|Bacteria,1RJST@1224|Proteobacteria,1S5SD@1236|Gammaproteobacteria,1X617@135614|Xanthomonadales	135614|Xanthomonadales	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
LZS3_k127_803643_6	530564.Psta_2542	1.044e-104	355.0	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_803643_9	530564.Psta_2300	5.382e-87	310.0	COG0673@1|root,COG0673@2|Bacteria,2IX0C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_803643_19	1278073.MYSTI_03893	5.607e-07	57.0	COG5512@1|root,COG5512@2|Bacteria,1N6KK@1224|Proteobacteria,42TK4@68525|delta/epsilon subdivisions,2WSPG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
LZS3_k127_803643_15	234267.Acid_1074	4.257e-29	119.0	COG0721@1|root,COG0721@2|Bacteria,3Y5QA@57723|Acidobacteria	57723|Acidobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
LZS3_k127_803643_2	204669.Acid345_0501	1.834e-185	591.0	COG0154@1|root,COG0154@2|Bacteria,3Y2PE@57723|Acidobacteria,2JIE0@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS3_k127_803643_5	234267.Acid_1660	2.202e-157	508.0	COG0075@1|root,COG0075@2|Bacteria,3Y3I6@57723|Acidobacteria	57723|Acidobacteria	E	aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS3_k127_803643_1	234267.Acid_1661	8.817e-191	611.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_803643_12	234267.Acid_6210	5.315e-45	168.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
LZS3_k127_803643_0	234267.Acid_2573	4.155e-202	638.0	COG0541@1|root,COG0541@2|Bacteria,3Y3AU@57723|Acidobacteria	57723|Acidobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
LZS3_k127_803643_17	1267535.KB906767_gene3055	2.327e-21	101.0	COG0228@1|root,COG0228@2|Bacteria,3Y56G@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
LZS3_k127_803643_16	234267.Acid_2571	3.966e-26	111.0	COG1837@1|root,COG1837@2|Bacteria,3Y5N5@57723|Acidobacteria	57723|Acidobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
LZS3_k127_803643_14	234267.Acid_2570	5.845e-40	156.0	COG0806@1|root,COG0806@2|Bacteria	2|Bacteria	J	ribosome binding	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
LZS3_k127_803643_8	234267.Acid_2569	3.358e-87	295.0	COG0336@1|root,COG0336@2|Bacteria,3Y3CS@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
LZS3_k127_803643_13	1267535.KB906767_gene3059	1.44e-40	153.0	COG0335@1|root,COG0335@2|Bacteria,3Y4P6@57723|Acidobacteria,2JJ9V@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
LZS3_k127_803643_11	234267.Acid_2565	1.082e-67	238.0	COG0164@1|root,COG0164@2|Bacteria,3Y49K@57723|Acidobacteria	57723|Acidobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS3_k127_803643_18	234267.Acid_2564	9.95e-15	78.0	2DTVW@1|root,33MW2@2|Bacteria,3Y606@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_803643_10	1267535.KB906767_gene5001	2.935e-72	271.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
LZS3_k127_803643_4	1123258.AQXZ01000012_gene2110	6.79e-163	524.0	COG1249@1|root,COG1249@2|Bacteria,2GPG1@201174|Actinobacteria,4FXNE@85025|Nocardiaceae	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS3_k127_8108988_1	1340493.JNIF01000003_gene3118	2.692e-208	689.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Dioxygenase_C,Plug,TonB_dep_Rec
LZS3_k127_8108988_0	314285.KT71_14034	8.828e-215	686.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1J9RR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_8108988_3	1267535.KB906767_gene218	3.937e-142	486.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8108988_2	926566.Terro_2385	1.393e-143	476.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria,2JKDV@204432|Acidobacteriia	204432|Acidobacteriia	S	amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
LZS3_k127_8108988_4	251229.Chro_3389	2.9e-46	174.0	2CYFR@1|root,32T44@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
LZS3_k127_8138123_1	1267535.KB906767_gene2247	1.197e-248	778.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
LZS3_k127_8138123_5	1340493.JNIF01000003_gene2581	6.811e-26	115.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
LZS3_k127_8138123_6	1340493.JNIF01000003_gene4423	5.084e-12	76.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	ymxG	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_8138123_3	234267.Acid_2026	8.483e-207	650.0	COG1219@1|root,COG1219@2|Bacteria,3Y3MR@57723|Acidobacteria	57723|Acidobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
LZS3_k127_8138123_0	234267.Acid_2027	0.0	1218.0	COG0466@1|root,COG0466@2|Bacteria,3Y3DI@57723|Acidobacteria	57723|Acidobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS3_k127_8138123_4	717605.Theco_2578	1.553e-46	175.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,26RHP@186822|Paenibacillaceae	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
LZS3_k127_8138123_2	1267535.KB906767_gene3177	1.367e-233	730.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
LZS3_k127_8161624_11	234267.Acid_1744	3.244e-21	99.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941,ko:K06350	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D,SLH
LZS3_k127_8161624_2	926549.KI421517_gene1092	9.761e-124	421.0	COG3420@1|root,COG3420@2|Bacteria,4P1XP@976|Bacteroidetes,47UIA@768503|Cytophagia	976|Bacteroidetes	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8161624_3	886293.Sinac_2092	2.177e-104	352.0	28KEJ@1|root,2ZA0T@2|Bacteria,2J2GX@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8161624_12	1340493.JNIF01000004_gene154	2.905e-20	93.0	2EK70@1|root,33DXD@2|Bacteria,3Y5QD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8161624_7	234267.Acid_1337	2.5e-67	240.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Glyoxalase
LZS3_k127_8161624_13	886293.Sinac_5997	3.805e-15	79.0	2EK31@1|root,33DTF@2|Bacteria,2J1NA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF997
LZS3_k127_8161624_4	575540.Isop_1362	8.908e-95	329.0	COG4145@1|root,COG4145@2|Bacteria,2IYD0@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.1	-	-	SSF
LZS3_k127_8161624_1	234267.Acid_5204	1.754e-135	446.0	COG1232@1|root,COG1232@2|Bacteria,3Y2X5@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS3_k127_8161624_8	398512.JQKC01000014_gene1570	9.828e-50	192.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,24AE3@186801|Clostridia,3WN8Q@541000|Ruminococcaceae	186801|Clostridia	GK	Transcriptional regulator sugar kinase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
LZS3_k127_8161624_9	1340493.JNIF01000003_gene1910	3.555e-45	170.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,rRNA_methylase
LZS3_k127_8161624_6	1340493.JNIF01000003_gene1816	1.55e-75	265.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	He_PIG,NHL,SGL
LZS3_k127_8161624_0	521674.Plim_3789	7.481e-194	625.0	COG1166@1|root,COG1166@2|Bacteria,2IX6P@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
LZS3_k127_8161624_10	1206731.BAGB01000063_gene7395	4.91e-22	106.0	COG3618@1|root,COG3618@2|Bacteria,2IE24@201174|Actinobacteria,4G6M7@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_8161624_5	1487953.JMKF01000078_gene4122	1.66e-93	313.0	COG1940@1|root,COG1940@2|Bacteria,1G0YU@1117|Cyanobacteria,1H786@1150|Oscillatoriales	1117|Cyanobacteria	GK	Transcriptional regulator sugar kinase	ppgK	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
LZS3_k127_8179835_6	1380394.JADL01000001_gene3082	5.383e-111	368.0	COG1077@1|root,COG1077@2|Bacteria,1RE7M@1224|Proteobacteria	1224|Proteobacteria	D	Cell shape determining protein MreB Mrl	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8179835_11	234267.Acid_1995	4.163e-62	231.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K11066,ko:K12287	-	-	-	-	ko00000,ko01000,ko01011,ko02044	-	-	-	Amidase_2
LZS3_k127_8179835_5	234267.Acid_3576	2.473e-126	415.0	COG1600@1|root,COG1600@2|Bacteria,3Y3TQ@57723|Acidobacteria	57723|Acidobacteria	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
LZS3_k127_8179835_0	1382359.JIAL01000001_gene12	1.909e-299	934.0	COG1964@1|root,COG1964@2|Bacteria,3Y2WC@57723|Acidobacteria,2JHTH@204432|Acidobacteriia	204432|Acidobacteriia	S	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
LZS3_k127_8179835_15	1123508.JH636445_gene6495	7.075e-45	166.0	COG0607@1|root,COG0607@2|Bacteria,2IZWR@203682|Planctomycetes	203682|Planctomycetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS3_k127_8179835_2	1267535.KB906767_gene3899	8.417e-215	676.0	COG0064@1|root,COG0064@2|Bacteria,3Y2TJ@57723|Acidobacteria,2JI20@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
LZS3_k127_8179835_16	234267.Acid_6760	4.348e-41	158.0	COG1399@1|root,COG1399@2|Bacteria,3Y4KJ@57723|Acidobacteria	57723|Acidobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
LZS3_k127_8179835_18	234267.Acid_6759	8.557e-21	92.0	COG0333@1|root,COG0333@2|Bacteria,3Y5HY@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
LZS3_k127_8179835_3	1267535.KB906767_gene696	1.336e-142	460.0	COG0416@1|root,COG0416@2|Bacteria,3Y3MM@57723|Acidobacteria,2JHTJ@204432|Acidobacteriia	204432|Acidobacteriia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
LZS3_k127_8179835_8	1123242.JH636434_gene5198	4.466e-92	319.0	COG1520@1|root,COG1520@2|Bacteria,2IY92@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
LZS3_k127_8179835_19	1123400.KB904746_gene1291	2.715e-20	101.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,463MH@72273|Thiotrichales	72273|Thiotrichales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_8179835_13	1254432.SCE1572_40520	2.285e-52	191.0	COG0537@1|root,COG0537@2|Bacteria,1PDTP@1224|Proteobacteria,42UAD@68525|delta/epsilon subdivisions,2WQRN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
LZS3_k127_8179835_14	682795.AciX8_0031	2.413e-45	171.0	COG0424@1|root,COG0424@2|Bacteria,3Y4ZU@57723|Acidobacteria,2JJH8@204432|Acidobacteriia	204432|Acidobacteriia	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
LZS3_k127_8179835_7	204669.Acid345_0475	2.301e-98	338.0	COG2204@1|root,COG2204@2|Bacteria,3Y6FW@57723|Acidobacteria	57723|Acidobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_8179835_4	234267.Acid_1851	2.135e-138	464.0	COG0642@1|root,COG4252@1|root,COG2205@2|Bacteria,COG4252@2|Bacteria	2|Bacteria	T	Chase2 domain	phoR_2	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,HisKA,PAS_4
LZS3_k127_8179835_10	234267.Acid_6683	9.312e-70	255.0	COG1566@1|root,COG1566@2|Bacteria	2|Bacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005,ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS3_k127_8179835_9	649747.HMPREF0083_05253	6.419e-92	308.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,26QNA@186822|Paenibacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
LZS3_k127_8179835_20	1297742.A176_07211	5.427e-12	78.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_8179835_12	929713.NIASO_20250	4.27e-62	227.0	COG4126@1|root,COG4126@2|Bacteria,4NHAM@976|Bacteroidetes,1IQAE@117747|Sphingobacteriia	976|Bacteroidetes	E	Asp Glu hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
LZS3_k127_8179835_1	1267535.KB906767_gene2719	9.849e-231	735.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.102	ko:K06978,ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	AXE1,Big_5,LTD,Peptidase_S9,Tannase
LZS3_k127_8195555_18	1173024.KI912149_gene5522	7.866e-23	103.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
LZS3_k127_8195555_6	401526.TcarDRAFT_1841	2.598e-91	307.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4H217@909932|Negativicutes	909932|Negativicutes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
LZS3_k127_8195555_10	234267.Acid_6223	1.47e-61	219.0	COG0054@1|root,COG0054@2|Bacteria,3Y3RR@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
LZS3_k127_8195555_15	234267.Acid_6222	3.309e-36	141.0	COG0781@1|root,COG0781@2|Bacteria,3Y4Z7@57723|Acidobacteria	57723|Acidobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
LZS3_k127_8195555_12	153948.NAL212_2253	5.863e-44	164.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,2VWKN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
LZS3_k127_8195555_11	794903.OPIT5_30730	2.868e-49	180.0	COG5507@1|root,COG5507@2|Bacteria,46VQ8@74201|Verrucomicrobia,3K9QM@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
LZS3_k127_8195555_0	1267535.KB906767_gene3396	1.977e-230	715.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
LZS3_k127_8195555_19	765420.OSCT_1752	2.011e-14	75.0	COG1724@1|root,COG1724@2|Bacteria,2G9TH@200795|Chloroflexi	200795|Chloroflexi	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
LZS3_k127_8195555_13	2002.JOEQ01000031_gene1648	3.382e-43	162.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4EPKG@85012|Streptosporangiales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
LZS3_k127_8195555_8	1121378.KB899735_gene4195	1.847e-79	273.0	COG0410@1|root,COG0410@2|Bacteria,1WM31@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K11963	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
LZS3_k127_8195555_7	1121378.KB899735_gene4194	1.941e-89	304.0	COG4674@1|root,COG4674@2|Bacteria,1WMA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC transporter	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
LZS3_k127_8195555_4	745310.G432_07245	5.434e-118	390.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2TTN2@28211|Alphaproteobacteria,2K1B7@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
LZS3_k127_8195555_9	566466.NOR53_2085	1.301e-71	252.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,1RQXD@1236|Gammaproteobacteria,1J5EH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	urtB	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2,HEAT_2
LZS3_k127_8195555_2	1121382.JQKG01000001_gene2454	5.654e-167	535.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	urtA	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
LZS3_k127_8195555_17	1121405.dsmv_1230	2.03e-27	128.0	COG3746@1|root,COG3746@2|Bacteria,1QXPF@1224|Proteobacteria,42TW0@68525|delta/epsilon subdivisions,2WQ4G@28221|Deltaproteobacteria,2MNVB@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
LZS3_k127_8195555_14	1121382.JQKG01000001_gene2442	4.654e-39	158.0	COG0829@1|root,COG0829@2|Bacteria	2|Bacteria	O	nickel cation binding	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
LZS3_k127_8195555_1	204669.Acid345_2969	1.135e-180	597.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,3Y3GW@57723|Acidobacteria,2JHKK@204432|Acidobacteriia	204432|Acidobacteriia	I	Phosphate acyltransferases	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
LZS3_k127_8195555_16	565033.GACE_0632	1.204e-32	134.0	COG2020@1|root,arCOG03580@2157|Archaea,2XXNN@28890|Euryarchaeota	28890|Euryarchaeota	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
LZS3_k127_8195555_3	1210884.HG799468_gene13690	1.805e-156	511.0	COG3653@1|root,COG3653@2|Bacteria,2IXWQ@203682|Planctomycetes	203682|Planctomycetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
LZS3_k127_8195555_5	1267535.KB906767_gene4999	1.245e-116	383.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,CarboxypepD_reg,DUF1080,F5_F8_type_C,G5,G8,Glyco_hyd_101C,Glyco_hydro_101,Trypsin_2,YSIRK_signal,fn3
LZS3_k127_8231882_2	497964.CfE428DRAFT_0160	7.972e-193	620.0	COG1657@1|root,COG1657@2|Bacteria,46UEC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans,SQHop_cyclase_C
LZS3_k127_8231882_12	756272.Plabr_3971	5.521e-14	82.0	COG5029@1|root,COG5029@2|Bacteria,2IYVM@203682|Planctomycetes	203682|Planctomycetes	O	beta-subunit of geranylgeranyltransferase or farnesyltransferase	-	-	2.5.1.60	ko:K05956	-	-	-	-	ko00000,ko01000,ko01006,ko04131	-	-	-	Prenyltrans
LZS3_k127_8231882_1	497964.CfE428DRAFT_0155	7.362e-230	724.0	COG0142@1|root,COG1852@1|root,COG0142@2|Bacteria,COG1852@2|Bacteria,46TEA@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116,polyprenyl_synt
LZS3_k127_8231882_3	1123242.JH636435_gene1438	2.18e-169	542.0	COG0535@1|root,COG0535@2|Bacteria,2IX8N@203682|Planctomycetes	203682|Planctomycetes	S	enzyme of the MoaA nifB pqqE family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS3_k127_8231882_6	1403819.BATR01000187_gene6443	2.346e-94	318.0	COG1146@1|root,COG1146@2|Bacteria,46TI2@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8231882_8	497964.CfE428DRAFT_6361	2.063e-35	138.0	2FICZ@1|root,34A57@2|Bacteria,46W7Z@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8231882_5	240016.ABIZ01000001_gene994	6.38e-120	396.0	COG0523@1|root,COG0523@2|Bacteria,46URF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SRP54-type protein, GTPase domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
LZS3_k127_8231882_7	497964.CfE428DRAFT_6360	1.967e-39	157.0	COG0509@1|root,COG0509@2|Bacteria,46WCE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
LZS3_k127_8231882_4	765912.Thimo_2710	3.89e-139	455.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1WXTN@135613|Chromatiales	135613|Chromatiales	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS3_k127_8231882_0	1340493.JNIF01000003_gene4764	9.587e-271	847.0	arCOG10801@1|root,2Z9IC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8231882_9	1396141.BATP01000029_gene2265	2.519e-33	136.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	-	-	3.6.4.12	ko:K02316,ko:K17680	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03029,ko03032	-	-	-	DUF3991,DnaB_C,Toprim_2,Toprim_3,Toprim_N,zf-CHC2
LZS3_k127_8231882_11	234267.Acid_1609	3.214e-29	119.0	2E3RU@1|root,32YPG@2|Bacteria,3Y8WT@57723|Acidobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8241567_13	234267.Acid_5602	2.91e-07	52.0	COG0598@1|root,COG0598@2|Bacteria,3Y4BT@57723|Acidobacteria	57723|Acidobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS3_k127_8241567_5	436229.JOEH01000029_gene4937	1.623e-74	267.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,2NMDX@228398|Streptacidiphilus	201174|Actinobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
LZS3_k127_8241567_6	1444309.JAQG01000073_gene306	8.509e-64	234.0	COG2159@1|root,COG2159@2|Bacteria,1TSSX@1239|Firmicutes,4HE0Z@91061|Bacilli,275Y6@186822|Paenibacillaceae	91061|Bacilli	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_8241567_8	234267.Acid_5845	1.691e-52	196.0	28JIP@1|root,2Z82C@2|Bacteria,3Y82Y@57723|Acidobacteria	57723|Acidobacteria	S	PFAM S1 P1 nuclease	-	-	-	-	-	-	-	-	-	-	-	-	S1-P1_nuclease
LZS3_k127_8241567_7	204669.Acid345_1382	5.622e-57	202.0	2BM3X@1|root,33KY1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8241567_2	247490.KSU1_B0458	9.863e-248	773.0	COG0364@1|root,COG0364@2|Bacteria,2IXCV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
LZS3_k127_8241567_0	1174528.JH992893_gene5975	0.0	1324.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1G15G@1117|Cyanobacteria,1JHXK@1189|Stigonemataceae	1117|Cyanobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
LZS3_k127_8241567_9	1128421.JAGA01000003_gene2880	3.286e-18	90.0	2ASAK@1|root,31HPU@2|Bacteria,2NQ6K@2323|unclassified Bacteria	2|Bacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
LZS3_k127_8241567_4	1128421.JAGA01000003_gene2879	4.856e-77	263.0	COG1845@1|root,COG1845@2|Bacteria,2NPIG@2323|unclassified Bacteria	2|Bacteria	C	cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
LZS3_k127_8241567_1	1123242.JH636434_gene3641	2.765e-283	878.0	COG0843@1|root,COG0843@2|Bacteria,2IXCQ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
LZS3_k127_8241567_3	234267.Acid_0497	9.907e-119	389.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
LZS3_k127_8261580_1	641524.ADICYQ_1796	5.802e-109	366.0	COG3964@1|root,COG3964@2|Bacteria,4NI4W@976|Bacteroidetes,47M3B@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_8261580_0	234267.Acid_3945	1.476e-255	794.0	COG0043@1|root,COG0043@2|Bacteria,3Y3BY@57723|Acidobacteria	57723|Acidobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
LZS3_k127_8261580_3	234267.Acid_3244	1.297e-83	290.0	COG2133@1|root,COG2133@2|Bacteria,3Y7A7@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
LZS3_k127_8261580_2	1123242.JH636435_gene1818	1.938e-104	355.0	COG2358@1|root,COG2358@2|Bacteria,2IY5Z@203682|Planctomycetes	203682|Planctomycetes	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
LZS3_k127_8261580_4	1121373.KB903620_gene2135	1.408e-08	61.0	28MZ6@1|root,2Z9YX@2|Bacteria,4NHU4@976|Bacteroidetes,47UJV@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8313985_24	861299.J421_5609	1.46e-73	263.0	COG1879@1|root,COG1879@2|Bacteria,1ZV3Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
LZS3_k127_8313985_33	347834.RHE_CH00321	1.28e-21	100.0	COG3450@1|root,COG3450@2|Bacteria,1RGQY@1224|Proteobacteria,2U7ET@28211|Alphaproteobacteria,4BA4Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	enzyme of the cupin superfamily	MA20_19475	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
LZS3_k127_8313985_29	1382306.JNIM01000001_gene2380	4.186e-41	168.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
LZS3_k127_8313985_2	401053.AciPR4_1439	9.126e-261	840.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_8313985_0	344747.PM8797T_23599	1.253e-303	955.0	COG2010@1|root,COG2010@2|Bacteria,2J2MP@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
LZS3_k127_8313985_4	344747.PM8797T_23604	2.294e-206	655.0	COG4102@1|root,COG4102@2|Bacteria,2J1TY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_8313985_6	344747.PM8797T_23604	2.459e-193	615.0	COG4102@1|root,COG4102@2|Bacteria,2J1TY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
LZS3_k127_8313985_28	1273538.G159_02005	2.574e-43	174.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,4HDE3@91061|Bacilli,26FY2@186818|Planococcaceae	91061|Bacilli	GK	Sugar kinase	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
LZS3_k127_8313985_35	204669.Acid345_1062	3.364e-19	93.0	COG3695@1|root,COG3695@2|Bacteria,3Y5FU@57723|Acidobacteria,2JK0H@204432|Acidobacteriia	204432|Acidobacteriia	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
LZS3_k127_8313985_36	941449.dsx2_3242	2.353e-12	81.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MH92@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,DUF3365,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
LZS3_k127_8313985_3	1340493.JNIF01000004_gene454	4.346e-213	688.0	COG1249@1|root,COG1249@2|Bacteria	2|Bacteria	C	cell redox homeostasis	M1-534	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored,SLH
LZS3_k127_8313985_27	234267.Acid_0424	1.156e-47	190.0	COG1470@1|root,COG1520@1|root,COG1470@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889,ko:K13735,ko:K17713,ko:K20276	ko02024,ko05100,map02024,map05100	-	R03136	-	ko00000,ko00001,ko01000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2
LZS3_k127_8313985_39	909663.KI867150_gene2417	1.601e-08	61.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
LZS3_k127_8313985_38	2340.JV46_19830	2.873e-11	72.0	COG1366@1|root,COG1366@2|Bacteria,1N6U1@1224|Proteobacteria	1224|Proteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS3_k127_8313985_41	1122134.KB893650_gene1414	9.783e-06	60.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria,1XMJV@135619|Oceanospirillales	135619|Oceanospirillales	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
LZS3_k127_8313985_9	682795.AciX8_0334	1.316e-182	627.0	COG0457@1|root,COG0457@2|Bacteria	682795.AciX8_0334|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8313985_13	234267.Acid_0592	6.907e-136	440.0	COG0492@1|root,COG0492@2|Bacteria,3Y2W6@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS3_k127_8313985_20	1340493.JNIF01000003_gene1742	2.568e-83	287.0	COG1082@1|root,COG1082@2|Bacteria,3Y4ZI@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_8313985_30	204669.Acid345_2183	4.237e-39	154.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
LZS3_k127_8313985_10	1267535.KB906767_gene2548	1.311e-179	589.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
LZS3_k127_8313985_25	1033737.CAEV01000065_gene2769	1.086e-70	251.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,36E9R@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_8313985_19	518766.Rmar_0331	6.128e-84	296.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1FJUG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
LZS3_k127_8313985_40	1267535.KB906767_gene5072	5.475e-08	61.0	COG4758@1|root,COG4758@2|Bacteria,3Y554@57723|Acidobacteria,2JNA4@204432|Acidobacteriia	204432|Acidobacteriia	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
LZS3_k127_8313985_17	497964.CfE428DRAFT_1821	5.368e-96	325.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
LZS3_k127_8313985_14	234267.Acid_5925	9.271e-131	428.0	COG2008@1|root,COG2008@2|Bacteria,3Y472@57723|Acidobacteria	57723|Acidobacteria	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS3_k127_8313985_1	472759.Nhal_2509	8.967e-294	915.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,1RPGT@1236|Gammaproteobacteria,1WW8N@135613|Chromatiales	135613|Chromatiales	I	Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS3_k127_8313985_34	481448.Minf_2462	5.602e-20	94.0	COG2146@1|root,COG2146@2|Bacteria,46WQG@74201|Verrucomicrobia,37HBF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Rieske-like [2Fe-2S] domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
LZS3_k127_8313985_21	402777.KB235903_gene852	3.393e-80	284.0	COG1216@1|root,COG1216@2|Bacteria,1G0PG@1117|Cyanobacteria,1H8A8@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_8313985_11	234267.Acid_3675	1.726e-151	493.0	COG1921@1|root,COG1921@2|Bacteria,3Y39V@57723|Acidobacteria	57723|Acidobacteria	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
LZS3_k127_8313985_23	1267535.KB906767_gene780	1.922e-78	267.0	COG0231@1|root,COG0231@2|Bacteria,3Y373@57723|Acidobacteria,2JIEA@204432|Acidobacteriia	204432|Acidobacteriia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
LZS3_k127_8313985_8	1267535.KB906767_gene4059	1.363e-184	586.0	COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria,2JIIN@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS3_k127_8313985_22	1254432.SCE1572_04140	1.811e-79	279.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,43F2R@68525|delta/epsilon subdivisions,2X35T@28221|Deltaproteobacteria,2YUDS@29|Myxococcales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
LZS3_k127_8313985_5	1267535.KB906767_gene310	1.344e-195	618.0	COG3964@1|root,COG3964@2|Bacteria,3Y42F@57723|Acidobacteria	57723|Acidobacteria	S	amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_8313985_12	234267.Acid_6147	2.677e-151	486.0	COG2006@1|root,COG2006@2|Bacteria,3Y705@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
LZS3_k127_8313985_18	289376.THEYE_A2044	6.774e-95	332.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	trkA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0015075,GO:0015672,GO:0016020,GO:0022857,GO:0030001,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0098655	-	ko:K03499,ko:K05571	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4,2.A.63.1,2.A.63.2	-	iE2348C_1286.E2348C_3552	TrkA_C,TrkA_N
LZS3_k127_8313985_15	525897.Dbac_2454	3.27e-130	431.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,42MPV@68525|delta/epsilon subdivisions,2WJBH@28221|Deltaproteobacteria,2M8CP@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS3_k127_8313985_42	7230.FBpp0173869	0.0008381	44.0	COG3119@1|root,KOG3731@2759|Eukaryota,38FCG@33154|Opisthokonta,3BBI1@33208|Metazoa,3CU4U@33213|Bilateria,41V6X@6656|Arthropoda,3SINX@50557|Insecta,44XRY@7147|Diptera,45RGM@7214|Drosophilidae	33208|Metazoa	G	sulfuric ester hydrolase activity. It is involved in the biological process described with metabolic process	SULF1	GO:0000902,GO:0000904,GO:0001501,GO:0001502,GO:0001655,GO:0001817,GO:0001819,GO:0001822,GO:0001889,GO:0001936,GO:0001937,GO:0002062,GO:0002063,GO:0003002,GO:0003008,GO:0003012,GO:0003014,GO:0003094,GO:0003156,GO:0003674,GO:0003824,GO:0004065,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0005795,GO:0005886,GO:0006022,GO:0006029,GO:0006082,GO:0006355,GO:0006357,GO:0006790,GO:0006807,GO:0006928,GO:0006935,GO:0006936,GO:0006939,GO:0006950,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007444,GO:0007447,GO:0007450,GO:0008037,GO:0008038,GO:0008039,GO:0008045,GO:0008146,GO:0008150,GO:0008152,GO:0008284,GO:0008285,GO:0008449,GO:0008484,GO:0008589,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009605,GO:0009611,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009953,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010468,GO:0010556,GO:0010574,GO:0010575,GO:0010646,GO:0010647,GO:0010648,GO:0012505,GO:0014831,GO:0014846,GO:0015012,GO:0015015,GO:0016020,GO:0016043,GO:0016201,GO:0016525,GO:0016740,GO:0016782,GO:0016787,GO:0016788,GO:0017095,GO:0019219,GO:0019222,GO:0019538,GO:0021675,GO:0022008,GO:0022603,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030166,GO:0030177,GO:0030178,GO:0030182,GO:0030198,GO:0030201,GO:0030202,GO:0030203,GO:0030334,GO:0030336,GO:0030510,GO:0030513,GO:0031099,GO:0031100,GO:0031175,GO:0031323,GO:0031326,GO:0031984,GO:0032501,GO:0032502,GO:0032835,GO:0032836,GO:0032879,GO:0032989,GO:0032990,GO:0034483,GO:0034645,GO:0035107,GO:0035108,GO:0035220,GO:0035222,GO:0035295,GO:0035860,GO:0036022,GO:0040011,GO:0040012,GO:0040013,GO:0040036,GO:0040037,GO:0042058,GO:0042059,GO:0042127,GO:0042221,GO:0042330,GO:0043009,GO:0043062,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044281,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045121,GO:0045765,GO:0045879,GO:0045880,GO:0045992,GO:0045995,GO:0048010,GO:0048190,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048660,GO:0048661,GO:0048666,GO:0048667,GO:0048699,GO:0048705,GO:0048706,GO:0048731,GO:0048732,GO:0048736,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0050919,GO:0051093,GO:0051171,GO:0051216,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051270,GO:0051271,GO:0051716,GO:0060173,GO:0060255,GO:0060348,GO:0060384,GO:0060429,GO:0060685,GO:0060686,GO:0060688,GO:0060828,GO:0061008,GO:0061448,GO:0061564,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072006,GO:0080090,GO:0090090,GO:0090092,GO:0090100,GO:0090263,GO:0090287,GO:0090288,GO:0097205,GO:0097421,GO:0097485,GO:0098589,GO:0098743,GO:0098791,GO:0098805,GO:0098857,GO:0120036,GO:0120039,GO:1901135,GO:1901137,GO:1901184,GO:1901185,GO:1901342,GO:1901343,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1903510,GO:1905330,GO:1905331,GO:2000026,GO:2000027,GO:2000112,GO:2000145,GO:2000146,GO:2000181,GO:2000241,GO:2000242,GO:2000345,GO:2001141	-	ko:K14607	-	-	-	-	ko00000,ko01000	-	-	-	DUF3740,Sulfatase
LZS3_k127_8313985_7	234267.Acid_6511	5.399e-187	602.0	COG2234@1|root,COG2234@2|Bacteria,3Y3S9@57723|Acidobacteria	57723|Acidobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
LZS3_k127_8313985_16	639030.JHVA01000001_gene2540	3.996e-96	326.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_8313985_26	1173027.Mic7113_2201	2.295e-65	230.0	COG5421@1|root,COG5421@2|Bacteria,1G3YW@1117|Cyanobacteria,1HHRP@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
LZS3_k127_8342308_8	234267.Acid_4362	5.055e-30	126.0	COG0457@1|root,COG0457@2|Bacteria,3Y4XQ@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS3_k127_8342308_3	1267535.KB906767_gene5312	7.168e-118	391.0	COG0391@1|root,COG0391@2|Bacteria,3Y3ZE@57723|Acidobacteria,2JITK@204432|Acidobacteriia	204432|Acidobacteriia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
LZS3_k127_8342308_12	1267535.KB906767_gene4949	1.793e-17	89.0	2FIG5@1|root,34A8B@2|Bacteria,3Y8GN@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8342308_0	1121904.ARBP01000021_gene3579	1.078e-162	525.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
LZS3_k127_8342308_1	234267.Acid_4222	7.516e-148	478.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,3Y2WU@57723|Acidobacteria	57723|Acidobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
LZS3_k127_8342308_2	1267535.KB906767_gene4183	6.282e-130	422.0	COG0552@1|root,COG0552@2|Bacteria,3Y3JQ@57723|Acidobacteria,2JIXJ@204432|Acidobacteriia	204432|Acidobacteriia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
LZS3_k127_8342308_13	1306947.ARQD01000006_gene24	2.228e-17	95.0	COG3202@1|root,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC
LZS3_k127_8342308_5	234267.Acid_3591	7.485e-89	302.0	COG1878@1|root,COG1878@2|Bacteria,3Y72H@57723|Acidobacteria	57723|Acidobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
LZS3_k127_8342308_4	234267.Acid_3094	1.738e-116	402.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y59I@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8342308_6	1167006.UWK_02852	1.444e-71	254.0	COG1624@1|root,COG1624@2|Bacteria,1N12B@1224|Proteobacteria,42UVR@68525|delta/epsilon subdivisions,2WQ2R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
LZS3_k127_8342308_9	290397.Adeh_1449	6.335e-27	117.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_8342308_11	997296.PB1_10142	1.534e-21	102.0	COG2032@1|root,COG2032@2|Bacteria,1V652@1239|Firmicutes,4HH67@91061|Bacilli,1ZE46@1386|Bacillus	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0046872,GO:0046914,GO:0046983,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
LZS3_k127_8342308_14	1123517.JOMR01000001_gene210	4.47e-09	64.0	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,1TDZA@1236|Gammaproteobacteria,463HC@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8342308_15	240015.ACP_2764	3.906e-07	55.0	COG4980@1|root,COG4980@2|Bacteria,3Y5HP@57723|Acidobacteria,2JJWE@204432|Acidobacteriia	204432|Acidobacteriia	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS3_k127_8342308_10	265072.Mfla_1015	1.11e-23	103.0	2DQZQ@1|root,339JR@2|Bacteria,1NNI2@1224|Proteobacteria,2W5R6@28216|Betaproteobacteria,2KN9M@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8413765_8	1128421.JAGA01000003_gene3091	2.995e-38	164.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS3_k127_8413765_3	189426.PODO_10530	2.537e-96	344.0	COG5652@1|root,COG5652@2|Bacteria,1VR6Y@1239|Firmicutes,4HTUP@91061|Bacilli,26V0H@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
LZS3_k127_8413765_1	266117.Rxyl_0923	7.225e-186	589.0	COG0075@1|root,COG0075@2|Bacteria,2GM5F@201174|Actinobacteria,4CQFE@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase, class V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
LZS3_k127_8413765_4	234267.Acid_5592	1.515e-79	277.0	COG1845@1|root,COG1845@2|Bacteria,3Y5GJ@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
LZS3_k127_8413765_7	204669.Acid345_0439	1.434e-42	164.0	COG1845@1|root,COG1845@2|Bacteria,3Y2KJ@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
LZS3_k127_8413765_0	1227739.Hsw_3114	6.344e-196	629.0	COG0843@1|root,COG0843@2|Bacteria,4NEH8@976|Bacteroidetes,47JBQ@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	coxN	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
LZS3_k127_8413765_5	234267.Acid_5589	6.324e-76	263.0	COG1622@1|root,COG1622@2|Bacteria,3Y4UA@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
LZS3_k127_8413765_2	886293.Sinac_2603	1.086e-103	346.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_8413765_6	1144310.PMI07_005417	1.133e-64	231.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
LZS3_k127_8450449_2	1210884.HG799465_gene11870	5.365e-44	161.0	COG2128@1|root,COG2128@2|Bacteria,2IZDY@203682|Planctomycetes	203682|Planctomycetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS3_k127_8450449_1	1267535.KB906767_gene4310	1.049e-131	430.0	COG2377@1|root,COG2377@2|Bacteria,3Y3CU@57723|Acidobacteria,2JI1E@204432|Acidobacteriia	204432|Acidobacteriia	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
LZS3_k127_8450449_0	234267.Acid_4760	0.0	1092.0	COG0249@1|root,COG0249@2|Bacteria,3Y2J5@57723|Acidobacteria	57723|Acidobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
LZS3_k127_8563667_10	234267.Acid_5171	1.85e-27	119.0	COG0438@1|root,COG0438@2|Bacteria,3Y7XP@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_8563667_5	234267.Acid_5170	2.039e-95	318.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	lgtF	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
LZS3_k127_8563667_9	234267.Acid_5168	1.013e-40	152.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U4@57723|Acidobacteria	57723|Acidobacteria	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS3_k127_8563667_7	234267.Acid_1422	4.722e-64	225.0	COG0290@1|root,COG0290@2|Bacteria,3Y3VP@57723|Acidobacteria	57723|Acidobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
LZS3_k127_8563667_3	641524.ADICYQ_3013	7.605e-109	366.0	COG0673@1|root,COG3733@1|root,COG0673@2|Bacteria,COG3733@2|Bacteria,4NN43@976|Bacteroidetes,47UBC@768503|Cytophagia	976|Bacteroidetes	Q	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_8563667_8	864069.MicloDRAFT_00025880	1.654e-60	221.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS3_k127_8563667_4	1123242.JH636434_gene4334	3.671e-97	325.0	COG0223@1|root,COG0223@2|Bacteria,2J4NR@203682|Planctomycetes	203682|Planctomycetes	J	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
LZS3_k127_8563667_0	1340493.JNIF01000003_gene1929	4.371e-161	517.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	MA20_31690	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_8563667_6	204669.Acid345_0999	2.032e-83	295.0	COG1680@1|root,COG1680@2|Bacteria,3Y7Q7@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_8563667_2	886293.Sinac_1477	2.409e-120	399.0	COG1073@1|root,COG1073@2|Bacteria,2IYBP@203682|Planctomycetes	203682|Planctomycetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8563667_1	1267535.KB906767_gene1686	1.396e-134	443.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
LZS3_k127_8585535_4	234267.Acid_2556	3.606e-152	491.0	COG2252@1|root,COG2252@2|Bacteria,3Y2I3@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Xanthine uracil vitamin C permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
LZS3_k127_8585535_3	1210884.HG799469_gene14066	1.69e-169	548.0	COG2421@1|root,COG2421@2|Bacteria,2J06T@203682|Planctomycetes	203682|Planctomycetes	C	acetamidase formamidase	-	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
LZS3_k127_8585535_8	1267535.KB906767_gene3960	1.608e-117	401.0	COG1215@1|root,COG2804@1|root,COG1215@2|Bacteria,COG2804@2|Bacteria,3Y6KA@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyl transferase family group 2	-	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,T2SSE_N
LZS3_k127_8585535_17	237368.SCABRO_00762	1.105e-54	205.0	28I4Y@1|root,2Z88D@2|Bacteria,2J2FV@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8585535_9	234267.Acid_7297	3.127e-108	363.0	COG0322@1|root,COG0322@2|Bacteria,3Y3HU@57723|Acidobacteria	57723|Acidobacteria	L	excinuclease ABC activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8585535_2	1121920.AUAU01000007_gene416	2.2e-195	632.0	COG1164@1|root,COG1164@2|Bacteria,3Y2SB@57723|Acidobacteria	57723|Acidobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
LZS3_k127_8585535_6	234267.Acid_2707	1.1e-122	411.0	COG0542@1|root,COG0542@2|Bacteria,3Y463@57723|Acidobacteria	57723|Acidobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
LZS3_k127_8585535_16	1123278.KB893408_gene18	1.08e-70	259.0	COG3391@1|root,COG3391@2|Bacteria,4NHHU@976|Bacteroidetes,47P02@768503|Cytophagia	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8585535_13	234267.Acid_6308	1.368e-88	304.0	COG2304@1|root,COG2304@2|Bacteria,3Y2PC@57723|Acidobacteria	57723|Acidobacteria	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
LZS3_k127_8585535_24	1297742.A176_02529	2.404e-10	73.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
LZS3_k127_8585535_11	234267.Acid_7123	1.056e-93	321.0	COG0438@1|root,COG0438@2|Bacteria,3Y867@57723|Acidobacteria	57723|Acidobacteria	H	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_8585535_22	1236973.JCM9157_3537	7.697e-27	114.0	COG0346@1|root,COG0346@2|Bacteria,1VH3Z@1239|Firmicutes,4HNY3@91061|Bacilli,1ZGZ5@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_8585535_18	656024.FsymDg_3418	2.613e-49	185.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2H996@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
LZS3_k127_8585535_0	234267.Acid_7336	5.486e-228	716.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
LZS3_k127_8585535_7	331869.BAL199_24894	1.027e-121	404.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,4BSDH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Malate/L-lactate dehydrogenase	comC	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
LZS3_k127_8585535_12	530564.Psta_2353	6.692e-90	305.0	COG1090@1|root,COG1090@2|Bacteria,2IXEW@203682|Planctomycetes	203682|Planctomycetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
LZS3_k127_8585535_10	1267535.KB906767_gene606	3.125e-95	340.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria,2JJ7M@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
LZS3_k127_8585535_25	1050202.KB913024_gene1152	0.0003415	46.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,408BM@622450|Actinopolysporales	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iNJ661.Rv2130c	tRNA-synt_1e
LZS3_k127_8585535_1	1267535.KB906767_gene2442	3.881e-200	630.0	COG0821@1|root,COG0821@2|Bacteria,3Y2GU@57723|Acidobacteria,2JHND@204432|Acidobacteriia	204432|Acidobacteriia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
LZS3_k127_8585535_5	1185876.BN8_01526	5.626e-139	454.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,47MH7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_8585535_19	234267.Acid_7651	2.244e-36	152.0	COG1637@1|root,COG1637@2|Bacteria,3Y5TD@57723|Acidobacteria	57723|Acidobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	NucS
LZS3_k127_8585535_21	234267.Acid_7651	1.476e-31	132.0	COG1637@1|root,COG1637@2|Bacteria,3Y5TD@57723|Acidobacteria	57723|Acidobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	-	-	-	-	-	-	-	-	-	NucS
LZS3_k127_8585535_14	234267.Acid_7243	1.437e-83	292.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	-	-	1.1.3.15,1.1.3.46	ko:K00104,ko:K16422	ko00261,ko00630,ko01055,ko01100,ko01110,ko01120,ko01130,map00261,map00630,map01055,map01100,map01110,map01120,map01130	-	R00475,R06633	RC00042,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
LZS3_k127_8585535_15	234267.Acid_1586	4.889e-77	265.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096,ko:K07496	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
LZS3_k127_8612862_5	1340493.JNIF01000003_gene2004	9.793e-14	76.0	COG0001@1|root,COG0001@2|Bacteria,3Y3GA@57723|Acidobacteria	57723|Acidobacteria	H	PFAM Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_8612862_1	314230.DSM3645_09722	3.618e-177	569.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_8612862_0	1267535.KB906767_gene1677	7.353e-281	896.0	COG3474@1|root,COG3474@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K02305,ko:K08738	ko00910,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00910,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00529,M00595	R00294,R10151	RC02794,RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.10,3.D.4.6	-	-	Cytochrom_C,HEAT_2
LZS3_k127_8612862_2	234267.Acid_6309	1.077e-90	312.0	COG1091@1|root,COG1091@2|Bacteria,3Y3IG@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS3_k127_8612862_4	251221.35212460	5.7e-37	155.0	COG0667@1|root,COG0667@2|Bacteria,1G3RI@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_8612862_3	1340493.JNIF01000004_gene96	1.958e-85	299.0	COG1524@1|root,COG1524@2|Bacteria,3Y7AY@57723|Acidobacteria	57723|Acidobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_8612862_6	1206731.BAGB01000045_gene5050	3.799e-10	61.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4FVSE@85025|Nocardiaceae	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
LZS3_k127_863744_0	1121374.KB891576_gene602	4.386e-174	556.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,1RNYZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
LZS3_k127_863744_6	639030.JHVA01000001_gene2446	6.339e-41	168.0	COG0596@1|root,COG1073@1|root,COG0596@2|Bacteria,COG1073@2|Bacteria,3Y79B@57723|Acidobacteria,2JK85@204432|Acidobacteriia	204432|Acidobacteriia	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_863744_7	234267.Acid_7472	4.247e-32	128.0	COG1917@1|root,COG1917@2|Bacteria,3Y596@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_863744_4	309801.trd_A0087	2.486e-67	237.0	COG1028@1|root,COG1028@2|Bacteria,2G8II@200795|Chloroflexi,27XKN@189775|Thermomicrobia	189775|Thermomicrobia	IQ	Dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_863744_1	234267.Acid_5863	4.729e-173	585.0	COG4386@1|root,COG4386@2|Bacteria,3Y76B@57723|Acidobacteria	57723|Acidobacteria	S	tail sheath protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_863744_5	1122919.KB905562_gene2429	8.837e-57	209.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,26TNV@186822|Paenibacillaceae	91061|Bacilli	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
LZS3_k127_863744_2	234267.Acid_3734	1.289e-90	306.0	COG1735@1|root,COG1735@2|Bacteria,3Y646@57723|Acidobacteria	57723|Acidobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_863744_3	314230.DSM3645_10132	1.777e-78	275.0	COG1073@1|root,COG1073@2|Bacteria,2IYEI@203682|Planctomycetes	203682|Planctomycetes	Q	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
LZS3_k127_8656150_4	671143.DAMO_3093	1.979e-26	111.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
LZS3_k127_8656150_3	97139.C824_02719	1.532e-63	233.0	COG1479@1|root,COG1479@2|Bacteria,1VHC8@1239|Firmicutes,24PSV@186801|Clostridia,36W3S@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
LZS3_k127_8656150_6	234267.Acid_0056	3.819e-12	71.0	COG1598@1|root,COG1598@2|Bacteria,3Y8TW@57723|Acidobacteria	57723|Acidobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
LZS3_k127_8656150_0	1267535.KB906767_gene5432	1.795e-96	329.0	COG0414@1|root,COG0414@2|Bacteria,3Y40A@57723|Acidobacteria,2JHS1@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
LZS3_k127_8656150_1	1267535.KB906767_gene5433	8.212e-96	324.0	COG0413@1|root,COG0413@2|Bacteria,3Y3GX@57723|Acidobacteria,2JI6Y@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
LZS3_k127_8656150_2	1267535.KB906767_gene5434	1.611e-64	231.0	COG5495@1|root,COG5495@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
LZS3_k127_8656150_5	69395.JQLZ01000007_gene1746	1.604e-16	94.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,1QVGM@1224|Proteobacteria,2TWFQ@28211|Alphaproteobacteria,2KJS0@204458|Caulobacterales	204458|Caulobacterales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
LZS3_k127_8725874_17	880072.Desac_1859	5.576e-22	97.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,2MR0A@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
LZS3_k127_8725874_9	1267535.KB906767_gene747	2.373e-50	186.0	COG1825@1|root,COG1825@2|Bacteria,3Y41C@57723|Acidobacteria,2JHW5@204432|Acidobacteriia	204432|Acidobacteriia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
LZS3_k127_8725874_8	234267.Acid_7094	1.543e-64	226.0	COG0193@1|root,COG0193@2|Bacteria,3Y48V@57723|Acidobacteria	57723|Acidobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
LZS3_k127_8725874_14	1267535.KB906767_gene745	1.554e-34	137.0	COG0360@1|root,COG0360@2|Bacteria,3Y50N@57723|Acidobacteria	57723|Acidobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
LZS3_k127_8725874_16	1267533.KB906734_gene4260	1.592e-23	103.0	COG0238@1|root,COG0238@2|Bacteria,3Y53K@57723|Acidobacteria,2JN1Z@204432|Acidobacteriia	204432|Acidobacteriia	J	Ribosomal protein S18	-	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
LZS3_k127_8725874_12	204669.Acid345_4535	2.286e-41	158.0	COG0359@1|root,COG0359@2|Bacteria,3Y4MD@57723|Acidobacteria,2JJAN@204432|Acidobacteriia	204432|Acidobacteriia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
LZS3_k127_8725874_4	1267535.KB906767_gene4273	1.234e-91	310.0	COG1028@1|root,COG1028@2|Bacteria,3Y7U3@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_8725874_5	1210884.HG799462_gene8785	3.976e-70	242.0	COG0693@1|root,COG0693@2|Bacteria,2IYYE@203682|Planctomycetes	203682|Planctomycetes	S	intracellular protease	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
LZS3_k127_8725874_10	234267.Acid_6375	4.722e-48	179.0	COG0352@1|root,COG0352@2|Bacteria,3Y53Y@57723|Acidobacteria	57723|Acidobacteria	H	PFAM thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
LZS3_k127_8725874_0	644282.Deba_0170	5.691e-270	844.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS3_k127_8725874_3	1340493.JNIF01000003_gene2440	1.142e-129	426.0	COG0484@1|root,COG0484@2|Bacteria,3Y2XW@57723|Acidobacteria	57723|Acidobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS3_k127_8725874_13	240015.ACP_0804	2.678e-41	156.0	COG0789@1|root,COG0789@2|Bacteria,3Y4KX@57723|Acidobacteria,2JJA1@204432|Acidobacteriia	204432|Acidobacteriia	K	MerR HTH family regulatory protein	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
LZS3_k127_8725874_1	485913.Krac_4321	5.439e-224	703.0	COG1012@1|root,COG1012@2|Bacteria,2G8B9@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_8725874_15	1340493.JNIF01000003_gene2288	1.152e-26	111.0	COG0724@1|root,COG0724@2|Bacteria	2|Bacteria	K	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_8725874_2	575540.Isop_3665	2.76e-140	458.0	COG0673@1|root,COG0673@2|Bacteria,2IX5C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_8725874_7	1340493.JNIF01000004_gene245	6.783e-66	232.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,CarboxypepD_reg,DUF1080,F5_F8_type_C,G5,G8,Glyco_hyd_101C,Glyco_hydro_101,Trypsin_2,YSIRK_signal,fn3
LZS3_k127_8725874_6	1089551.KE386572_gene299	1.575e-67	241.0	28TQ4@1|root,2ZFXE@2|Bacteria	2|Bacteria	S	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
LZS3_k127_8725874_11	1267535.KB906767_gene33	3.514e-45	172.0	COG1385@1|root,COG1385@2|Bacteria,3Y3XJ@57723|Acidobacteria,2JI6A@204432|Acidobacteriia	204432|Acidobacteriia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
LZS3_k127_8760318_1	234267.Acid_3608	2.02e-151	484.0	COG0318@1|root,COG0318@2|Bacteria,3Y74C@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_8760318_0	880070.Cycma_0177	1.041e-163	533.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8760318_2	234267.Acid_6718	2.856e-145	467.0	COG1577@1|root,COG1577@2|Bacteria	2|Bacteria	I	mevalonate kinase activity	mvaK2	-	2.7.1.36,2.7.1.43,2.7.4.2	ko:K00869,ko:K00938,ko:K16190	ko00040,ko00053,ko00520,ko00900,ko01100,ko01110,ko01130,ko04146,map00040,map00053,map00520,map00900,map01100,map01110,map01130,map04146	M00014,M00095	R01476,R02245,R03245	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS3_k127_8760318_3	1442599.JAAN01000026_gene1201	1.384e-10	66.0	COG1983@1|root,COG1983@2|Bacteria,1NGIB@1224|Proteobacteria,1SGYQ@1236|Gammaproteobacteria,1XD0S@135614|Xanthomonadales	135614|Xanthomonadales	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
LZS3_k127_8760318_4	1122222.AXWR01000002_gene2193	1.411e-08	56.0	COG1490@1|root,COG1490@2|Bacteria,1WJUX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
LZS3_k127_8765617_0	234267.Acid_2395	0.0	1452.0	COG0458@1|root,COG0458@2|Bacteria,3Y3GG@57723|Acidobacteria	57723|Acidobacteria	F	TIGRFAM carbamoyl-phosphate synthase, large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
LZS3_k127_8765617_1	234267.Acid_2394	2.043e-172	552.0	COG0505@1|root,COG0505@2|Bacteria,3Y31Y@57723|Acidobacteria	57723|Acidobacteria	EF	TIGRFAM Carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
LZS3_k127_8765617_3	234267.Acid_0799	3.847e-64	229.0	COG0681@1|root,COG0681@2|Bacteria,3Y49Z@57723|Acidobacteria	57723|Acidobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
LZS3_k127_8765617_4	1128421.JAGA01000002_gene1580	9.889e-17	94.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
LZS3_k127_8765617_2	251221.35211765	2.008e-159	533.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_942105_2	401526.TcarDRAFT_0365	1.087e-86	297.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4H2DY@909932|Negativicutes	909932|Negativicutes	C	Phosphate acetyl/butaryl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PTA_PTB
LZS3_k127_942105_0	234267.Acid_0380	5.282e-128	421.0	COG1502@1|root,COG1502@2|Bacteria,3Y2GD@57723|Acidobacteria	57723|Acidobacteria	I	PLD-like domain	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
LZS3_k127_942105_3	204669.Acid345_0496	5.996e-76	263.0	COG3568@1|root,COG3568@2|Bacteria,3Y4HM@57723|Acidobacteria,2JKST@204432|Acidobacteriia	204432|Acidobacteriia	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
LZS3_k127_942105_4	1340493.JNIF01000003_gene2857	6.128e-41	165.0	COG4254@1|root,COG4254@2|Bacteria,3Y90P@57723|Acidobacteria	57723|Acidobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
LZS3_k127_942105_7	987059.RBXJA2T_18388	2.818e-38	151.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VIAK@28216|Betaproteobacteria,1KMB3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
LZS3_k127_942105_6	234267.Acid_6689	3.946e-39	159.0	COG2062@1|root,COG2062@2|Bacteria,3Y5YQ@57723|Acidobacteria	57723|Acidobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS3_k127_942105_5	234267.Acid_2835	1.162e-40	162.0	COG1322@1|root,COG1322@2|Bacteria,3Y3JC@57723|Acidobacteria	57723|Acidobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_942105_1	1247726.MIM_c08130	1.214e-113	373.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VH0T@28216|Betaproteobacteria,3T4W3@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Dienelactone hydrolase and related enzymes	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
## 4668 queries scanned
## Total time (seconds): 183.07243967056274
## Rate: 25.50 q/s