## Tue Feb 17 19:26:37 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/LZS3_bin.84.fa -m mmseqs --output LZS3_bin.84 --output_dir /data/result/bins/wyx/eggqs50+/LZS3_bin.84 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
LZS3_k127_1104536_9	1120965.AUBV01000012_gene1393	8.594e-73	250.0	COG0702@1|root,COG0702@2|Bacteria,4NMI5@976|Bacteroidetes,47R0K@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
LZS3_k127_1104536_0	1191523.MROS_2744	4.895e-236	741.0	COG4799@1|root,COG4799@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01966,ko:K01969	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00036,M00373,M00741	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS3_k127_1104536_8	1304883.KI912532_gene720	1.003e-73	256.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,2KU7S@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_1104536_3	1168034.FH5T_18240	6.383e-164	530.0	COG0439@1|root,COG0439@2|Bacteria,4NFEQ@976|Bacteroidetes,2FMBN@200643|Bacteroidia	976|Bacteroidetes	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS3_k127_1104536_14	760568.Desku_1367	5.36e-18	91.0	COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,25F1E@186801|Clostridia,262F3@186807|Peptococcaceae	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
LZS3_k127_1104536_11	42256.RradSPS_1222	2.545e-58	212.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria,4CQ84@84995|Rubrobacteria	84995|Rubrobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
LZS3_k127_1104536_13	111781.Lepto7376_4316	5.887e-31	127.0	2CHH4@1|root,32SC0@2|Bacteria,1G6WJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
LZS3_k127_1104536_12	1185652.USDA257_c02620	8.24e-32	126.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,4BFST@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
LZS3_k127_1104536_5	1246459.KB898356_gene2162	6.381e-140	462.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,4B80H@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
LZS3_k127_1104536_6	1278073.MYSTI_02808	3.535e-109	363.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
LZS3_k127_1104536_2	1125863.JAFN01000001_gene766	6.389e-174	558.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,42PAX@68525|delta/epsilon subdivisions,2WKEP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
LZS3_k127_1104536_1	1163617.SCD_n00015	2.399e-200	642.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
LZS3_k127_1104536_17	1499967.BAYZ01000118_gene3276	3.147e-08	66.0	COG1409@1|root,COG4916@1|root,COG1409@2|Bacteria,COG4916@2|Bacteria	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	GUN4,TIR_2,WD40
LZS3_k127_1104536_10	1499967.BAYZ01000076_gene815	6.933e-60	216.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_1104536_7	1121957.ATVL01000014_gene1459	3.613e-85	311.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1104536_4	903818.KI912268_gene2830	1.265e-160	531.0	COG0457@1|root,COG0457@2|Bacteria,3Y7KQ@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M49	-	-	3.4.14.4	ko:K01277	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M49
LZS3_k127_1104536_16	1266908.AQPB01000043_gene1453	1.379e-11	72.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,1RPAV@1236|Gammaproteobacteria,1WX4B@135613|Chromatiales	135613|Chromatiales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS3_k127_1142024_25	1121403.AUCV01000030_gene2790	1.065e-77	263.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MJGI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
LZS3_k127_1142024_68	391587.KAOT1_07673	7.649e-08	60.0	2CKAK@1|root,32SBZ@2|Bacteria,4NSJ2@976|Bacteroidetes,1I3ZA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1142024_52	882083.SacmaDRAFT_4319	2.671e-28	124.0	COG4978@1|root,COG4978@2|Bacteria,2IS9W@201174|Actinobacteria	201174|Actinobacteria	KT	Transcriptional regulator	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
LZS3_k127_1142024_9	414684.RC1_4071	1.759e-150	485.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2TVIF@28211|Alphaproteobacteria,2JVFI@204441|Rhodospirillales	204441|Rhodospirillales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
LZS3_k127_1142024_66	882083.SacmaDRAFT_4037	5.326e-09	65.0	COG2220@1|root,COG2220@2|Bacteria,2GMTR@201174|Actinobacteria,4E29G@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
LZS3_k127_1142024_30	1122134.KB893650_gene272	9.149e-72	261.0	COG3428@1|root,COG3428@2|Bacteria,1R51P@1224|Proteobacteria,1RNVC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
LZS3_k127_1142024_58	243090.RB5060	3.327e-15	83.0	COG3402@1|root,COG3402@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
LZS3_k127_1142024_15	1379698.RBG1_1C00001G0518	2.557e-110	388.0	COG0515@1|root,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
LZS3_k127_1142024_37	497964.CfE428DRAFT_0868	4.192e-54	197.0	COG2808@1|root,COG2808@2|Bacteria	2|Bacteria	K	Putative FMN-binding domain	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
LZS3_k127_1142024_69	1242864.D187_002928	7.958e-07	57.0	COG4968@1|root,COG4968@2|Bacteria,1QXNR@1224|Proteobacteria,43C4N@68525|delta/epsilon subdivisions,2WRDZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	pilA-N	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin_PilA
LZS3_k127_1142024_45	1237149.C900_00073	8.873e-40	156.0	COG0457@1|root,COG0457@2|Bacteria	1237149.C900_00073|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1142024_19	1237149.C900_00072	5.051e-95	321.0	COG1273@1|root,COG1273@2|Bacteria,4NHHQ@976|Bacteroidetes,47PE5@768503|Cytophagia	976|Bacteroidetes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
LZS3_k127_1142024_31	1231185.BAMP01000038_gene1093	1.039e-71	256.0	COG0739@1|root,COG0739@2|Bacteria,1MXH6@1224|Proteobacteria,2U25J@28211|Alphaproteobacteria,43IWF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS3_k127_1142024_59	404589.Anae109_3022	1.852e-14	83.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS3_k127_1142024_1	1237149.C900_00071	9.011e-292	915.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,4NESR@976|Bacteroidetes,47NMI@768503|Cytophagia	976|Bacteroidetes	L	DNA polymerase Ligase (LigD)	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
LZS3_k127_1142024_24	1210884.HG799465_gene11340	1.192e-80	295.0	COG1801@1|root,COG1801@2|Bacteria,2IYWM@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS3_k127_1142024_21	880073.Calab_1252	7.58e-93	335.0	COG2931@1|root,COG4677@1|root,COG2931@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	fitD	-	3.2.1.51,4.2.2.23	ko:K10297,ko:K15923,ko:K18197,ko:K19615	ko00511,ko02020,map00511,map02020	-	-	-	ko00000,ko00001,ko01000,ko02042,ko04121	-	GH95,PL11	-	Beta_helix,DUF1080,TcdA_TcdB_pore
LZS3_k127_1142024_18	880073.Calab_1252	1.235e-96	344.0	COG2931@1|root,COG4677@1|root,COG2931@2|Bacteria,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	fitD	-	3.2.1.51,4.2.2.23	ko:K10297,ko:K15923,ko:K18197,ko:K19615	ko00511,ko02020,map00511,map02020	-	-	-	ko00000,ko00001,ko01000,ko02042,ko04121	-	GH95,PL11	-	Beta_helix,DUF1080,TcdA_TcdB_pore
LZS3_k127_1142024_65	388399.SSE37_12736	6.842e-10	72.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,2U2JS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1142024_0	1279009.ADICEAN_03273	0.0	1251.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K8C@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_4	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
LZS3_k127_1142024_23	1121930.AQXG01000001_gene1272	2.186e-82	290.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,1IQN0@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
LZS3_k127_1142024_8	889378.Spiaf_2832	5.284e-154	493.0	COG0379@1|root,COG0379@2|Bacteria,2JAE2@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
LZS3_k127_1142024_56	880073.Calab_2402	1.906e-19	104.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1142024_14	1280706.AUJE01000021_gene914	9.654e-122	403.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,4H2VM@909932|Negativicutes	909932|Negativicutes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
LZS3_k127_1142024_72	318586.Pden_1123	0.0001063	54.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2TSQS@28211|Alphaproteobacteria,2PXPB@265|Paracoccus	28211|Alphaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_1142024_48	767817.Desgi_1600	2.272e-36	153.0	COG2202@1|root,COG3829@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,249RN@186801|Clostridia,264BR@186807|Peptococcaceae	186801|Clostridia	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,HATPase_c,HisKA,MASE3,PAS_4,PAS_9
LZS3_k127_1142024_7	1125863.JAFN01000001_gene1129	1.372e-161	528.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
LZS3_k127_1142024_63	1519464.HY22_05910	7.035e-12	78.0	COG0642@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,1FEYZ@1090|Chlorobi	1090|Chlorobi	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Y_Y_Y
LZS3_k127_1142024_22	671143.DAMO_1573	3.699e-90	319.0	COG0006@1|root,COG0006@2|Bacteria,2NP8P@2323|unclassified Bacteria	2|Bacteria	E	Metallopeptidase family M24	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Peptidase_M24
LZS3_k127_1142024_35	1519464.HY22_02355	3.02e-59	215.0	COG0613@1|root,COG0613@2|Bacteria,1FDKZ@1090|Chlorobi	1090|Chlorobi	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
LZS3_k127_1142024_62	314230.DSM3645_11547	4.646e-12	68.0	COG1225@1|root,COG1225@2|Bacteria,2IZIQ@203682|Planctomycetes	203682|Planctomycetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS3_k127_1142024_51	234267.Acid_7719	9.045e-34	132.0	COG1225@1|root,COG1225@2|Bacteria,3Y4Z6@57723|Acidobacteria	57723|Acidobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
LZS3_k127_1142024_50	756883.Halar_1451	3.375e-34	141.0	COG1985@1|root,arCOG01484@2157|Archaea	2157|Archaea	H	PFAM bifunctional deaminase-reductase domain protein	ribG	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
LZS3_k127_1142024_61	247490.KSU1_D0612	1.859e-12	76.0	COG2210@1|root,COG2210@2|Bacteria,2J3DW@203682|Planctomycetes	203682|Planctomycetes	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
LZS3_k127_1142024_40	300852.55771428	2.737e-53	205.0	COG0436@1|root,COG0436@2|Bacteria,1WIMB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_1142024_5	886377.Murru_1901	4.911e-170	563.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NF70@976|Bacteroidetes,1HWWX@117743|Flavobacteriia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
LZS3_k127_1142024_13	1122182.KB903815_gene1406	2.136e-125	409.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4D9Y1@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
LZS3_k127_1142024_38	1173028.ANKO01000112_gene4835	2.187e-53	195.0	COG0302@1|root,COG0302@2|Bacteria,1G1K8@1117|Cyanobacteria,1HF5A@1150|Oscillatoriales	1117|Cyanobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.folE,iJN678.folE	GTP_cyclohydroI
LZS3_k127_1142024_17	644966.Tmar_1229	1.317e-98	334.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3WCZD@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS3_k127_1142024_20	926569.ANT_11190	1.531e-94	312.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
LZS3_k127_1142024_42	1183438.GKIL_0508	4.01e-48	199.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria	1117|Cyanobacteria	F	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS3_k127_1142024_4	1158318.ATXC01000001_gene647	1.285e-196	625.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G3I9@200783|Aquificae	200783|Aquificae	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
LZS3_k127_1142024_64	1304284.L21TH_0708	1.03e-10	72.0	COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,24HZH@186801|Clostridia,36G4R@31979|Clostridiaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
LZS3_k127_1142024_26	459349.CLOAM0969	7.471e-77	267.0	COG0388@1|root,COG0388@2|Bacteria,2NPKU@2323|unclassified Bacteria	2|Bacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
LZS3_k127_1142024_67	321332.CYB_2752	9.22e-09	68.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1G0VR@1117|Cyanobacteria,1GZQK@1129|Synechococcus	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	ko:K06596,ko:K11526	ko02020,ko02025,map02020,map02025	M00507,M00508	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
LZS3_k127_1142024_70	999550.KI421507_gene1854	1.897e-06	57.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,2UM3F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
LZS3_k127_1142024_47	1379698.RBG1_1C00001G1089	1.858e-37	160.0	COG3437@1|root,COG3437@2|Bacteria,2NP8B@2323|unclassified Bacteria	2|Bacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HD,HD_5,PAS,PAS_3,PAS_9,Response_reg
LZS3_k127_1142024_27	644282.Deba_2013	4.54e-75	272.0	COG0745@1|root,COG2203@1|root,COG2206@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,Response_reg
LZS3_k127_1142024_57	880073.Calab_2401	3.319e-17	96.0	COG2374@1|root,COG2374@2|Bacteria,2NRB5@2323|unclassified Bacteria	2|Bacteria	G	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,FlgD_ig,LTD
LZS3_k127_1142024_12	1123371.ATXH01000004_gene1748	4.577e-138	471.0	COG0612@1|root,COG0612@2|Bacteria,2GH66@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_1142024_33	1209989.TepiRe1_0359	2.344e-68	240.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,42FDQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
LZS3_k127_1142024_32	1123060.JONP01000001_gene1435	1.362e-70	249.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,2JP97@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
LZS3_k127_1142024_2	1379698.RBG1_1C00001G1627	1.045e-223	713.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
LZS3_k127_1142024_41	1379698.RBG1_1C00001G1628	7.682e-49	183.0	COG0634@1|root,COG0634@2|Bacteria,2NPER@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.2.8,2.7.4.3,6.3.4.19	ko:K00760,ko:K00939,ko:K15780	ko00230,ko00730,ko00983,ko01100,ko01110,ko01130,map00230,map00730,map00983,map01100,map01110,map01130	M00049	R00127,R00190,R01132,R01229,R01547,R02142,R08237,R08238,R08245,R11319	RC00002,RC00063,RC00122	ko00000,ko00001,ko00002,ko01000,ko03016,ko04147	-	-	iHN637.CLJU_RS16720	ADK,Pribosyltran
LZS3_k127_1142024_39	1232410.KI421415_gene3041	2.463e-53	206.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,43S3D@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	TilS substrate binding domain	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
LZS3_k127_1142024_55	555779.Dthio_PD3775	5.913e-22	97.0	COG4226@1|root,COG4226@2|Bacteria,1PTX8@1224|Proteobacteria,4328E@68525|delta/epsilon subdivisions	1224|Proteobacteria	L	CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1142024_44	1385935.N836_11195	6.131e-42	162.0	COG1569@1|root,COG1569@2|Bacteria,1G7HY@1117|Cyanobacteria,1HD1I@1150|Oscillatoriales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
LZS3_k127_1142024_16	357808.RoseRS_1966	5.497e-99	334.0	COG0059@1|root,COG0059@2|Bacteria,2G5NP@200795|Chloroflexi,3758Y@32061|Chloroflexia	32061|Chloroflexia	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
LZS3_k127_1142024_10	4577.GRMZM2G450498_P01	1.873e-149	498.0	COG0626@1|root,KOG0053@2759|Eukaryota,37RGY@33090|Viridiplantae,3GB43@35493|Streptophyta,3KV4Q@4447|Liliopsida,3IGFF@38820|Poales	35493|Streptophyta	E	Cys/Met metabolism PLP-dependent enzyme	MGL	GO:0000096,GO:0000097,GO:0000098,GO:0001101,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0006950,GO:0007154,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009067,GO:0009068,GO:0009069,GO:0009070,GO:0009086,GO:0009087,GO:0009092,GO:0009267,GO:0009414,GO:0009415,GO:0009605,GO:0009628,GO:0009970,GO:0009987,GO:0009991,GO:0010035,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0018826,GO:0019343,GO:0019344,GO:0019346,GO:0019458,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0042221,GO:0042594,GO:0042631,GO:0043167,GO:0043168,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0048037,GO:0050662,GO:0050667,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0065003,GO:0070279,GO:0070887,GO:0071214,GO:0071229,GO:0071265,GO:0071266,GO:0071462,GO:0071496,GO:0071704,GO:0071840,GO:0097159,GO:0104004,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901700,GO:1901701	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
LZS3_k127_1142024_60	290397.Adeh_0802	3.394e-13	82.0	COG1999@1|root,COG1999@2|Bacteria,1R9EM@1224|Proteobacteria,42N5F@68525|delta/epsilon subdivisions,2WKG7@28221|Deltaproteobacteria,2YV22@29|Myxococcales	28221|Deltaproteobacteria	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	sco	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	-
LZS3_k127_1142024_3	925409.KI911562_gene954	3.229e-210	668.0	COG0843@1|root,COG0843@2|Bacteria,4P06K@976|Bacteroidetes	976|Bacteroidetes	C	Cytochrome C oxidase subunit I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
LZS3_k127_1142024_36	932678.THERU_02085	2.584e-54	194.0	COG1622@1|root,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	cbaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2-transmemb
LZS3_k127_1142024_46	1379698.RBG1_1C00001G0849	1.581e-37	146.0	COG1959@1|root,COG1959@2|Bacteria,2NQ8B@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, BadM Rrf2 family	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS3_k127_1142024_28	1122194.AUHU01000014_gene1147	2.568e-73	258.0	COG0500@1|root,COG2226@2|Bacteria,1QY1T@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1142024_6	1121930.AQXG01000002_gene2379	3.097e-164	531.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,4NE2Y@976|Bacteroidetes,1IUW3@117747|Sphingobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
LZS3_k127_1142024_53	266940.Krad_4304	5.015e-28	132.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
LZS3_k127_1142024_71	207559.Dde_0828	8.762e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42P80@68525|delta/epsilon subdivisions,2WMCB@28221|Deltaproteobacteria,2MG6A@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM PEP-CTERM system TPR-repeat lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS3_k127_1142024_11	502025.Hoch_2255	3.914e-142	464.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YX7D@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS3_k127_1142024_29	1379698.RBG1_1C00001G0710	1.614e-72	250.0	COG1945@1|root,COG1945@2|Bacteria,2NP74@2323|unclassified Bacteria	2|Bacteria	S	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC)	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
LZS3_k127_1142024_43	1123035.ARLA01000028_gene2417	6.677e-48	188.0	COG0010@1|root,COG0010@2|Bacteria,4NE01@976|Bacteroidetes,1HYIB@117743|Flavobacteriia,4C3DE@83612|Psychroflexus	976|Bacteroidetes	E	Arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
LZS3_k127_1142024_49	573413.Spirs_3120	8.205e-36	153.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	tnp3503b	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Transposase_mut
LZS3_k127_1142024_34	1167006.UWK_02488	2.158e-65	239.0	COG2271@1|root,COG2271@2|Bacteria,1NJTU@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	MA20_01130	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_1142024_54	1047013.AQSP01000134_gene1357	1.156e-22	115.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,TolB_like
LZS3_k127_1145941_4	867903.ThesuDRAFT_00022	1.822e-157	516.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WCF6@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS3_k127_1145941_33	1121946.AUAX01000034_gene6797	1.628e-18	93.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria,4DD5X@85008|Micromonosporales	201174|Actinobacteria	S	Modulates RecA activity	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
LZS3_k127_1145941_5	338963.Pcar_2405	2.713e-148	480.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,43S46@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Rad51	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
LZS3_k127_1145941_32	1121440.AUMA01000023_gene2053	3.978e-20	98.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2MCME@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
LZS3_k127_1145941_17	867903.ThesuDRAFT_00190	9.052e-77	280.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3WCJP@538999|Clostridiales incertae sedis	186801|Clostridia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
LZS3_k127_1145941_30	880073.Calab_1192	1.039e-28	122.0	COG1267@1|root,COG1267@2|Bacteria,2NPTB@2323|unclassified Bacteria	2|Bacteria	I	Phosphatidylglycerophosphatase A	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195,iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
LZS3_k127_1145941_1	383372.Rcas_0866	6.311e-215	675.0	COG3033@1|root,COG3033@2|Bacteria,2G7YV@200795|Chloroflexi,376SB@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS3_k127_1145941_2	886293.Sinac_1688	6.453e-211	665.0	COG3033@1|root,COG3033@2|Bacteria,2J41D@203682|Planctomycetes	203682|Planctomycetes	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS3_k127_1145941_15	859657.RPSI07_mp0608	1.111e-85	298.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria,1K5U4@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_1145941_3	886293.Sinac_0199	7.375e-187	595.0	COG0076@1|root,COG0076@2|Bacteria	2|Bacteria	E	glutamate decarboxylase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
LZS3_k127_1145941_14	472759.Nhal_2907	1.514e-88	321.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,1RNPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748,OmpA
LZS3_k127_1145941_16	639282.DEFDS_0024	1.163e-83	281.0	COG1100@1|root,COG1100@2|Bacteria,2GEYH@200930|Deferribacteres	200930|Deferribacteres	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
LZS3_k127_1145941_29	1379270.AUXF01000005_gene389	8.664e-37	145.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
LZS3_k127_1145941_18	47716.JOFH01000051_gene5063	5.553e-67	233.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
LZS3_k127_1145941_31	717231.Flexsi_0293	2.009e-23	104.0	COG0718@1|root,COG0718@2|Bacteria,2GFU9@200930|Deferribacteres	200930|Deferribacteres	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
LZS3_k127_1145941_11	443143.GM18_0169	1.087e-103	358.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
LZS3_k127_1145941_38	1530186.JQEY01000001_gene893	3.651e-09	59.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS3_k127_1145941_22	1265490.JHVY01000005_gene1421	5.666e-46	169.0	COG1607@1|root,COG1607@2|Bacteria,1RHNU@1224|Proteobacteria,1S4SW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyl-CoA hydrolase	VL23_09840	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS3_k127_1145941_37	1101191.KI912577_gene4342	8.23e-12	67.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2UJKX@28211|Alphaproteobacteria,1JW5Y@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
LZS3_k127_1145941_21	357808.RoseRS_3098	9.959e-50	190.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
LZS3_k127_1145941_40	1197906.CAJQ02000027_gene1525	0.0007898	52.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
LZS3_k127_1145941_27	1122939.ATUD01000003_gene3462	1.03e-38	151.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4CQ59@84995|Rubrobacteria	84995|Rubrobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
LZS3_k127_1145941_20	871968.DESME_14475	1.562e-58	220.0	COG0438@1|root,COG0438@2|Bacteria,1TSNT@1239|Firmicutes,248MH@186801|Clostridia	186801|Clostridia	M	Group 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
LZS3_k127_1145941_23	391625.PPSIR1_21764	1.577e-45	166.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,43C2Q@68525|delta/epsilon subdivisions,2WSJ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
LZS3_k127_1145941_8	517418.Ctha_0316	1.005e-123	441.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340,Gln_amidase
LZS3_k127_1145941_0	517418.Ctha_0317	3.391e-313	982.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
LZS3_k127_1145941_10	517418.Ctha_0318	2.595e-105	348.0	COG1131@1|root,COG1131@2|Bacteria,1FDTT@1090|Chlorobi	2|Bacteria	V	PFAM ABC transporter related	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
LZS3_k127_1145941_13	330214.NIDE1142	1.283e-88	310.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_1145941_35	491952.Mar181_2114	3.133e-14	85.0	COG0685@1|root,COG0685@2|Bacteria,1QGEE@1224|Proteobacteria,1RSEG@1236|Gammaproteobacteria,1XII7@135619|Oceanospirillales	135619|Oceanospirillales	E	Methylenetetrahydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
LZS3_k127_1145941_9	1242864.D187_009349	1.2e-115	417.0	COG2133@1|root,COG3291@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,1R86D@1224|Proteobacteria	1224|Proteobacteria	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,GSDH
LZS3_k127_1145941_34	880073.Calab_0921	3.133e-18	101.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_1145941_26	1170562.Cal6303_0175	6.035e-41	173.0	COG2133@1|root,COG2931@1|root,COG3299@1|root,COG2133@2|Bacteria,COG2931@2|Bacteria,COG3299@2|Bacteria,1G2CB@1117|Cyanobacteria,1HRM4@1161|Nostocales	1117|Cyanobacteria	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,GSDH,PA14
LZS3_k127_1145941_36	880073.Calab_1769	2.9e-13	83.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	CP_1072	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
LZS3_k127_1145941_19	552811.Dehly_0442	8.514e-60	220.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
LZS3_k127_1145941_25	1382359.JIAL01000001_gene327	1.268e-42	169.0	COG3005@1|root,COG3005@2|Bacteria,3Y4BJ@57723|Acidobacteria,2JJ2B@204432|Acidobacteriia	204432|Acidobacteriia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS3_k127_1145941_12	1379698.RBG1_1C00001G0779	1.841e-91	323.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
LZS3_k127_1145941_7	1379698.RBG1_1C00001G0780	3.156e-127	419.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
LZS3_k127_1145941_24	1379698.RBG1_1C00001G0781	1.831e-45	168.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
LZS3_k127_1145941_6	671143.DAMO_0825	5.095e-135	456.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NNNM@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b subunit of formate dehydrogenase-like protein	mccA	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0006790,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016002,GO:0016043,GO:0016491,GO:0016667,GO:0017144,GO:0019748,GO:0020037,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044272,GO:0044550,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051259,GO:0051260,GO:0055114,GO:0065003,GO:0070206,GO:0070207,GO:0070813,GO:0070814,GO:0071840,GO:0097159,GO:1901363,GO:1903136	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
LZS3_k127_1145941_28	1162668.LFE_1478	2.777e-37	147.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,SLH
LZS3_k127_1151455_0	243231.GSU0580	0.0	1065.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43TQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS3_k127_1151455_4	349521.HCH_01908	3.371e-06	57.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,1XMH8@135619|Oceanospirillales	135619|Oceanospirillales	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS3_k127_1151455_1	768670.Calni_1269	2.021e-17	90.0	COG0457@1|root,COG2214@1|root,COG0457@2|Bacteria,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DUF4388,DnaJ
LZS3_k127_1151455_3	517418.Ctha_0506	8.751e-10	70.0	COG1555@1|root,COG1555@2|Bacteria,1FE73@1090|Chlorobi	1090|Chlorobi	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
LZS3_k127_1151455_2	243274.THEMA_04985	7.544e-11	75.0	COG0296@1|root,COG0296@2|Bacteria,2GD7U@200918|Thermotogae	200918|Thermotogae	G	PFAM glycoside hydrolase, family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
LZS3_k127_1166748_19	525904.Tter_1710	7.233e-11	63.0	COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS3_k127_1166748_1	1110502.TMO_0578	7.735e-153	494.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2JPVB@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS3_k127_1166748_7	1499967.BAYZ01000196_gene3077	1.588e-67	233.0	COG1898@1|root,COG1898@2|Bacteria,2NP7U@2323|unclassified Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
LZS3_k127_1166748_4	880073.Calab_3419	2.369e-114	378.0	COG1088@1|root,COG1088@2|Bacteria,2NNRC@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46,4.2.1.76	ko:K01710,ko:K12450	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R00293,R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
LZS3_k127_1166748_3	880073.Calab_0614	2.179e-130	426.0	COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
LZS3_k127_1166748_14	547559.Nmag_3437	4.6e-24	117.0	COG2244@1|root,arCOG02209@2157|Archaea,2XVSG@28890|Euryarchaeota,23TS7@183963|Halobacteria	183963|Halobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
LZS3_k127_1166748_9	910314.HMPREF9220_1320	1.287e-45	181.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H2U9@909932|Negativicutes	909932|Negativicutes	M	Glycosyltransferase, group 4 family	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
LZS3_k127_1166748_11	546271.Selsp_0363	7.418e-39	156.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes	909932|Negativicutes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
LZS3_k127_1166748_2	138119.DSY0008	1.102e-132	435.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,260VV@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
LZS3_k127_1166748_6	518766.Rmar_1450	5.712e-75	269.0	COG0642@1|root,COG2205@2|Bacteria,4PKGE@976|Bacteroidetes,1FIRF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	vicK	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_1166748_15	517418.Ctha_2053	1.738e-22	115.0	COG1404@1|root,COG1404@2|Bacteria,1FFAM@1090|Chlorobi	1090|Chlorobi	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Peptidase_S8
LZS3_k127_1166748_18	880073.Calab_3215	4.269e-16	90.0	COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 70	-	-	3.1.11.2,3.2.1.1	ko:K01142,ko:K01176	ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000,ko03400	-	GH13	-	Alpha-amylase,CBM_25,DUF1939,He_PIG
LZS3_k127_1166748_20	290397.Adeh_2115	9.285e-11	64.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS3_k127_1166748_0	1379698.RBG1_1C00001G1545	1.108e-168	546.0	COG0745@1|root,COG0745@2|Bacteria,2NNXK@2323|unclassified Bacteria	2|Bacteria	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
LZS3_k127_1166748_13	1321781.HMPREF1985_00641	1.964e-26	114.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4H4ZR@909932|Negativicutes	909932|Negativicutes	S	Hydrolase, P-loop family	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
LZS3_k127_1166748_16	338963.Pcar_1913	1.251e-21	105.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,43UNS@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
LZS3_k127_1166748_12	373903.Hore_01970	2.462e-32	136.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WBVD@53433|Halanaerobiales	186801|Clostridia	J	Acetyltransferase (GNAT) domain	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS3_k127_1166748_17	1160137.KB907310_gene4992	1.025e-19	102.0	COG0005@1|root,COG0005@2|Bacteria,2GKEI@201174|Actinobacteria,4FX06@85025|Nocardiaceae	201174|Actinobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS3_k127_1166748_5	1379698.RBG1_1C00001G1549	2.566e-101	338.0	COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria	2|Bacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Carboxyl_trans
LZS3_k127_1166748_8	649638.Trad_1462	1.914e-61	229.0	COG0285@1|root,COG0285@2|Bacteria,1WI0C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	PFAM Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
LZS3_k127_1166748_10	945713.IALB_1053	4.407e-39	159.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	glcK	GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07790	ROK
LZS3_k127_119262_11	1049564.TevJSym_be00310	2.275e-53	199.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,1J5AH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
LZS3_k127_119262_15	404589.Anae109_1534	2.663e-21	106.0	COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2WRZ7@28221|Deltaproteobacteria,2YYH9@29|Myxococcales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_119262_8	1379698.RBG1_1C00001G0108	2.798e-66	244.0	COG0803@1|root,COG0803@2|Bacteria,2NPH3@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the bacterial solute-binding protein 9 family	znuA	-	-	ko:K02077,ko:K09815,ko:K09818	ko02010,map02010	M00242,M00243,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
LZS3_k127_119262_9	1379698.RBG1_1C00001G0109	8.635e-60	217.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
LZS3_k127_119262_6	404589.Anae109_2092	6.484e-82	293.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
LZS3_k127_119262_3	886293.Sinac_5561	3.152e-133	438.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_119262_2	886293.Sinac_5560	1.525e-134	454.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	ymxG	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_119262_18	1379270.AUXF01000003_gene3797	7.05e-07	62.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
LZS3_k127_119262_4	204669.Acid345_3011	2.189e-106	355.0	COG0150@1|root,COG0150@2|Bacteria,3Y2GN@57723|Acidobacteria,2JITJ@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS3_k127_119262_7	1304284.L21TH_2302	2.958e-74	266.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,25EWN@186801|Clostridia,36USS@31979|Clostridiaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF_2,HAMP,HD,HD_5,Reg_prop,Response_reg,Y_Y_Y,dCache_1
LZS3_k127_119262_16	138119.DSY0509	1.626e-18	94.0	2DMAW@1|root,32EM1@2|Bacteria,1UPNC@1239|Firmicutes,25HJQ@186801|Clostridia,2627W@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_119262_5	1379270.AUXF01000005_gene720	9.877e-88	299.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
LZS3_k127_119262_1	1304875.JAFZ01000001_gene1388	1.456e-136	452.0	COG0018@1|root,COG0018@2|Bacteria,3TA5K@508458|Synergistetes	508458|Synergistetes	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
LZS3_k127_119262_13	517418.Ctha_0064	1.216e-29	124.0	COG0799@1|root,COG0799@2|Bacteria,1FE3F@1090|Chlorobi	1090|Chlorobi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
LZS3_k127_119262_12	868864.Dester_0938	6.819e-44	169.0	COG0805@1|root,COG0805@2|Bacteria,2G41B@200783|Aquificae	200783|Aquificae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
LZS3_k127_119262_10	203119.Cthe_0450	5.84e-55	196.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3WJ07@541000|Ruminococcaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
LZS3_k127_119262_0	768704.Desmer_4568	4.741e-171	547.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,2609R@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
LZS3_k127_119262_14	697281.Mahau_0044	1.771e-25	121.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS3_k127_119262_17	1283287.KB822579_gene2005	1.127e-11	74.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,4DNBX@85009|Propionibacteriales	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
LZS3_k127_1283635_20	105559.Nwat_0643	4.379e-18	88.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X1A7@135613|Chromatiales	135613|Chromatiales	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS3_k127_1283635_1	1267535.KB906767_gene4695	6.319e-246	769.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
LZS3_k127_1283635_5	754476.Q7A_1535	4.11e-110	361.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,45ZRE@72273|Thiotrichales	72273|Thiotrichales	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
LZS3_k127_1283635_7	378806.STAUR_1771	2.551e-97	344.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2WN3M@28221|Deltaproteobacteria,2YY27@29|Myxococcales	28221|Deltaproteobacteria	O	Uncharacterized protein family (UPF0051)	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
LZS3_k127_1283635_2	290397.Adeh_0846	5.792e-165	549.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
LZS3_k127_1283635_9	296591.Bpro_4273	2.156e-54	194.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ3A@28216|Betaproteobacteria,4ADT9@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
LZS3_k127_1283635_13	1008457.BAEX01000020_gene1899	6.758e-31	131.0	COG2151@1|root,COG2151@2|Bacteria,4NSA9@976|Bacteroidetes,1I2WQ@117743|Flavobacteriia,47IAB@76831|Myroides	976|Bacteroidetes	S	Pfam:DUF59	yitW	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
LZS3_k127_1283635_10	1379270.AUXF01000001_gene2349	1.033e-50	183.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
LZS3_k127_1283635_19	1227266.HMPREF1551_00783	3.064e-18	92.0	28NRS@1|root,2ZBQZ@2|Bacteria,4NMM5@976|Bacteroidetes,1HYDM@117743|Flavobacteriia,1ER9M@1016|Capnocytophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1283635_17	395495.Lcho_3739	8.901e-22	108.0	COG0689@1|root,COG5276@1|root,COG0689@2|Bacteria,COG5276@2|Bacteria,1QVI5@1224|Proteobacteria	1224|Proteobacteria	N	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,He_PIG,LVIVD
LZS3_k127_1283635_6	330214.NIDE3960	3.413e-104	348.0	COG1611@1|root,COG1611@2|Bacteria,3J169@40117|Nitrospirae	40117|Nitrospirae	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
LZS3_k127_1283635_18	1265505.ATUG01000001_gene4158	7.539e-19	97.0	COG0560@1|root,COG3830@1|root,COG0560@2|Bacteria,COG3830@2|Bacteria,1MWA3@1224|Proteobacteria,42NIR@68525|delta/epsilon subdivisions,2WIVQ@28221|Deltaproteobacteria,2MJ7K@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ACT domain	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	ACT_6,HAD
LZS3_k127_1283635_11	1485545.JQLW01000010_gene1663	3.814e-46	173.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_1283635_26	582744.Msip34_1793	3.484e-06	53.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2W81G@28216|Betaproteobacteria,2KNB0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
LZS3_k127_1283635_14	96561.Dole_2883	2.285e-26	114.0	COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQHB@28221|Deltaproteobacteria,2MQ0A@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS3_k127_1283635_21	404380.Gbem_0575	2.346e-17	93.0	COG2259@1|root,COG2259@2|Bacteria,1NC5I@1224|Proteobacteria,42V27@68525|delta/epsilon subdivisions,2WS2G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Methylamine	-	-	-	-	-	-	-	-	-	-	-	-	MauE
LZS3_k127_1283635_4	368407.Memar_0694	7.5e-117	396.0	COG0367@1|root,arCOG00121@2157|Archaea	2157|Archaea	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS3_k127_1283635_8	525897.Dbac_2204	1.827e-54	211.0	COG0726@1|root,COG0726@2|Bacteria,1MZFC@1224|Proteobacteria,42M7D@68525|delta/epsilon subdivisions,2WKVW@28221|Deltaproteobacteria,2M97N@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS3_k127_1283635_23	425104.Ssed_2969	9.618e-11	74.0	COG2244@1|root,COG2244@2|Bacteria,1P0EB@1224|Proteobacteria	1224|Proteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
LZS3_k127_1283635_22	448385.sce2509	3.216e-17	93.0	COG1396@1|root,COG1762@1|root,COG1396@2|Bacteria,COG1762@2|Bacteria,1NBG9@1224|Proteobacteria,439HI@68525|delta/epsilon subdivisions,2X4TU@28221|Deltaproteobacteria,2YZKB@29|Myxococcales	28221|Deltaproteobacteria	GKT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_31,PTS_EIIA_2
LZS3_k127_1283635_3	1539298.JO41_11495	1.38e-125	414.0	COG0624@1|root,COG0624@2|Bacteria,2J5ZZ@203691|Spirochaetes	203691|Spirochaetes	E	COGs COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylase	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
LZS3_k127_1283635_24	1550091.JROE01000002_gene814	5.69e-09	67.0	COG4244@1|root,COG4244@2|Bacteria,4NG6K@976|Bacteroidetes,1IQ8G@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
LZS3_k127_1283635_15	867903.ThesuDRAFT_01495	3.166e-26	117.0	COG2120@1|root,COG2120@2|Bacteria,1TPSJ@1239|Firmicutes,24NQN@186801|Clostridia	186801|Clostridia	S	PFAM GlcNAc-PI de-N-acetylase	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
LZS3_k127_1283635_0	1089550.ATTH01000001_gene1136	3.181e-258	814.0	COG0348@1|root,COG0492@1|root,COG1249@1|root,COG0348@2|Bacteria,COG0492@2|Bacteria,COG1249@2|Bacteria,4PIT2@976|Bacteroidetes,1FJYA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
LZS3_k127_1283635_12	1304885.AUEY01000003_gene491	1.94e-43	163.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,2MK9C@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Iron-storage protein	ftn	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
LZS3_k127_1283635_25	1123508.JH636442_gene4097	1.992e-07	60.0	28NUF@1|root,33DCF@2|Bacteria,2J1TB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1469724_19	459349.CLOAM0602	6.779e-16	94.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.17.22	ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Cellulase,DUF4859,F5_F8_type_C,FlgD_ig
LZS3_k127_1469724_15	1408473.JHXO01000010_gene3766	9.364e-19	104.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria,4NGJJ@976|Bacteroidetes,2FRXF@200643|Bacteroidia	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1469724_13	459349.CLOAM0631	1.785e-24	123.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
LZS3_k127_1469724_1	760568.Desku_2105	3.093e-111	410.0	COG1404@1|root,COG3934@1|root,COG4733@1|root,COG1404@2|Bacteria,COG3934@2|Bacteria,COG4733@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,260VW@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651,ko:K13274,ko:K13276,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
LZS3_k127_1469724_4	378806.STAUR_1023	1.642e-71	275.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,438C4@68525|delta/epsilon subdivisions,2WYM4@28221|Deltaproteobacteria,2YWIJ@29|Myxococcales	28221|Deltaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_1469724_3	1134474.O59_003904	2.901e-80	291.0	COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,1RPAU@1236|Gammaproteobacteria,1FI1W@10|Cellvibrio	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3413)	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	DUF3413,Sulfatase
LZS3_k127_1469724_7	1242864.D187_002182	1.068e-55	203.0	COG4430@1|root,COG4430@2|Bacteria,1NEN6@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
LZS3_k127_1469724_17	880073.Calab_2081	8.484e-18	100.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_1469724_5	443254.Marpi_0645	7.299e-65	254.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CHU_C,HATPase_c,HTH_18,Kelch_1,PQQ_2,PQQ_3,Peptidase_C25,Propeptide_C25,Reg_prop,Response_reg,VCBS,Y_Y_Y
LZS3_k127_1469724_20	880073.Calab_2081	1.312e-15	92.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_1469724_11	443254.Marpi_1007	2.286e-38	166.0	COG1520@1|root,COG1520@2|Bacteria,2GD9T@200918|Thermotogae	200918|Thermotogae	S	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1469724_24	714943.Mucpa_2767	0.0001058	56.0	COG4733@1|root,COG4733@2|Bacteria,4NQRS@976|Bacteroidetes	976|Bacteroidetes	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1469724_18	880073.Calab_2214	2.513e-16	94.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	-
LZS3_k127_1469724_8	443254.Marpi_0645	2.917e-52	213.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CHU_C,HATPase_c,HTH_18,Kelch_1,PQQ_2,PQQ_3,Peptidase_C25,Propeptide_C25,Reg_prop,Response_reg,VCBS,Y_Y_Y
LZS3_k127_1469724_12	573413.Spirs_3120	7.504e-38	160.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	tnp3503b	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Transposase_mut
LZS3_k127_1469724_16	1519464.HY22_02735	2.594e-18	102.0	COG1404@1|root,COG1404@2|Bacteria,1FER7@1090|Chlorobi	1090|Chlorobi	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS3_k127_1469724_25	253839.SSNG_02823	0.0005692	43.0	2BKZQ@1|root,32FGG@2|Bacteria,2GZN6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1469724_21	1121912.AUHD01000007_gene399	5.931e-10	74.0	COG5276@1|root,COG5276@2|Bacteria,4NPJY@976|Bacteroidetes,1I2K9@117743|Flavobacteriia	976|Bacteroidetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SusE,fn3
LZS3_k127_1469724_9	443254.Marpi_1007	5.17e-47	196.0	COG1520@1|root,COG1520@2|Bacteria,2GD9T@200918|Thermotogae	200918|Thermotogae	S	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1469724_0	511051.CSE_10010	5.055e-168	538.0	COG0017@1|root,COG0017@2|Bacteria	2|Bacteria	J	Asparaginyl-tRNA synthetase	asnS	GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS3_k127_1469724_22	292459.STH3324	3.068e-05	57.0	COG0457@1|root,COG0457@2|Bacteria	292459.STH3324|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1469724_23	1499967.BAYZ01000115_gene2918	4.554e-05	55.0	COG0745@1|root,COG0745@2|Bacteria	1499967.BAYZ01000115_gene2918|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1469724_14	1379698.RBG1_1C00001G1024	2.817e-23	112.0	COG0382@1|root,COG0382@2|Bacteria,2NRJ9@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.39,2.5.1.62	ko:K03179,ko:K04040	ko00130,ko00860,ko01100,ko01110,map00130,map00860,map01100,map01110	M00117	R05000,R05615,R06284,R09067,R11514,R11517	RC00020,RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS3_k127_1469724_10	1379698.RBG1_1C00001G1162	1.145e-40	161.0	COG0726@1|root,COG0726@2|Bacteria,2NPY1@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Polysacc_deac_1
LZS3_k127_1469724_2	321332.CYB_1262	8.158e-100	338.0	COG0436@1|root,COG0436@2|Bacteria,1G0X8@1117|Cyanobacteria,1GYF8@1129|Synechococcus	1117|Cyanobacteria	E	I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iJN678.aspC	Aminotran_1_2
LZS3_k127_1469724_6	246194.CHY_1148	1.411e-56	208.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,42ERN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM peptidase M16 domain protein	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_1531330_3	1463825.JNXC01000001_gene6215	1.727e-05	56.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4E1T5@85010|Pseudonocardiales	201174|Actinobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
LZS3_k127_1531330_2	861299.J421_1503	1.929e-44	168.0	COG2318@1|root,COG2318@2|Bacteria,1ZU0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS3_k127_1531330_1	1463934.JOCF01000026_gene7236	1.032e-86	316.0	COG2898@1|root,COG2898@2|Bacteria,2GM2C@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterised conserved protein (DUF2156)	lysX	-	-	-	-	-	-	-	-	-	-	-	DUF2156,Rhomboid
LZS3_k127_1531330_0	247490.KSU1_D0315	5.757e-110	370.0	COG1007@1|root,COG1007@2|Bacteria,2IXC6@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
LZS3_k127_1647458_0	1379698.RBG1_1C00001G1080	1.192e-185	602.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
LZS3_k127_1647458_3	945713.IALB_2314	3.845e-47	192.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
LZS3_k127_1647458_2	1267533.KB906733_gene3472	3.383e-121	437.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,3Y67Y@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12,TPR_8
LZS3_k127_1647458_4	234267.Acid_1209	1.56e-41	159.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
LZS3_k127_1647458_1	1379698.RBG1_1C00001G0805	1.147e-160	517.0	COG1012@1|root,COG1012@2|Bacteria,2NNWB@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128,ko:K00138	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_1670833_19	269799.Gmet_0975	9.005e-60	231.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43UJ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
LZS3_k127_1670833_34	1265505.ATUG01000002_gene2047	4.647e-16	87.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2MJVB@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	PFAM Pilus assembly protein PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
LZS3_k127_1670833_35	1163617.SCD_n02942	3.105e-14	79.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,2VN9T@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	PFAM Fimbrial assembly family protein	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
LZS3_k127_1670833_13	379066.GAU_2518	5.341e-75	264.0	COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
LZS3_k127_1670833_18	338966.Ppro_0982	2.57e-61	221.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
LZS3_k127_1670833_29	1047013.AQSP01000066_gene720	6.329e-21	101.0	COG0457@1|root,COG0457@2|Bacteria	1047013.AQSP01000066_gene720|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1670833_28	1265505.ATUG01000003_gene184	4.106e-25	122.0	COG1277@1|root,COG1277@2|Bacteria,1NCXV@1224|Proteobacteria,42VK2@68525|delta/epsilon subdivisions,2WRNT@28221|Deltaproteobacteria,2MPXF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
LZS3_k127_1670833_17	290397.Adeh_0636	9.567e-68	244.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YXY8@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_1670833_38	515635.Dtur_0878	1.801e-11	70.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Lectin_C,N_methyl,SBP_bac_10,T2SSG
LZS3_k127_1670833_3	1379698.RBG1_1C00001G1210	4.672e-159	514.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_1670833_14	1499967.BAYZ01000027_gene1787	3.162e-73	268.0	COG5000@1|root,COG5000@2|Bacteria,2NP6K@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
LZS3_k127_1670833_6	379066.GAU_2568	8.679e-133	434.0	COG1459@1|root,COG1459@2|Bacteria,1ZT63@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
LZS3_k127_1670833_4	243231.GSU1492	1.039e-139	454.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,43TEX@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS3_k127_1670833_2	639282.DEFDS_1109	3.259e-196	632.0	COG2804@1|root,COG2804@2|Bacteria,2GEP7@200930|Deferribacteres	200930|Deferribacteres	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
LZS3_k127_1670833_41	1043493.BBLU01000002_gene1782	1.603e-07	58.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria	201174|Actinobacteria	L	Competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
LZS3_k127_1670833_31	379066.GAU_1933	1.689e-18	100.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
LZS3_k127_1670833_8	1121422.AUMW01000005_gene654	6.701e-111	372.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,260J1@186807|Peptococcaceae	186801|Clostridia	Q	PFAM Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
LZS3_k127_1670833_1	316274.Haur_0629	1.333e-249	784.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi,376GE@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
LZS3_k127_1670833_5	1122221.JHVI01000004_gene119	3.39e-138	458.0	COG2986@1|root,COG2986@2|Bacteria,1WISU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Phenylalanine and histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
LZS3_k127_1670833_27	1191523.MROS_0530	1.96e-25	123.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS3_k127_1670833_12	945713.IALB_1764	1.654e-78	297.0	COG5448@1|root,COG5448@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
LZS3_k127_1670833_36	927677.ALVU02000001_gene3372	5.308e-14	83.0	COG3391@1|root,COG3391@2|Bacteria,1G499@1117|Cyanobacteria	1117|Cyanobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,VPEP
LZS3_k127_1670833_33	1379698.RBG1_1C00001G1785	9.998e-17	93.0	2EAWV@1|root,334Y2@2|Bacteria,2NRSF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1670833_32	1379698.RBG1_1C00001G1786	2.321e-18	95.0	2CUTJ@1|root,32SW3@2|Bacteria,2NRD1@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1670833_24	459349.CLOAM1225	1.827e-41	165.0	COG2067@1|root,COG2067@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_1670833_9	1379698.RBG1_1C00001G1789	5.615e-100	368.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
LZS3_k127_1670833_37	760142.Hipma_0205	6.155e-14	73.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria,2M7FV@213113|Desulfurellales	28221|Deltaproteobacteria	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
LZS3_k127_1670833_7	1297742.A176_00494	1.101e-114	381.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,2YU4X@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
LZS3_k127_1670833_25	1379698.RBG1_1C00001G1526	1.164e-26	128.0	2CBA8@1|root,30BZT@2|Bacteria,2NR2H@2323|unclassified Bacteria	2|Bacteria	S	Exopolysaccharide biosynthesis protein YbjH	-	-	-	-	-	-	-	-	-	-	-	-	YjbH
LZS3_k127_1670833_0	1379698.RBG1_1C00001G0460	0.0	1100.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
LZS3_k127_1670833_23	313596.RB2501_11777	3.323e-42	176.0	COG0739@1|root,COG0739@2|Bacteria,4NED7@976|Bacteroidetes,1HXKD@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS3_k127_1670833_22	459349.CLOAM1011	4.229e-45	184.0	COG0760@1|root,COG0760@2|Bacteria,2NP7B@2323|unclassified Bacteria	2|Bacteria	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
LZS3_k127_1670833_40	449447.MAE_50440	1.224e-07	58.0	COG1826@1|root,COG1826@2|Bacteria,1G93D@1117|Cyanobacteria	1117|Cyanobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
LZS3_k127_1670833_42	1121104.AQXH01000009_gene2244	4.811e-06	54.0	COG1316@1|root,COG1316@2|Bacteria,4P5Q5@976|Bacteroidetes	976|Bacteroidetes	K	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C
LZS3_k127_1670833_21	1163730.FFONT_0979	8.416e-49	182.0	COG0537@1|root,arCOG00419@2157|Archaea,2XQK8@28889|Crenarchaeota	28889|Crenarchaeota	F	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
LZS3_k127_1670833_16	760568.Desku_0158	6.708e-68	244.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,2609P@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
LZS3_k127_1670833_15	1120971.AUCA01000001_gene1692	3.17e-72	253.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,2784W@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
LZS3_k127_1670833_10	269799.Gmet_1642	1.467e-97	327.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,43S2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
LZS3_k127_1670833_20	880073.Calab_2860	6.275e-59	211.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
LZS3_k127_1670833_26	1123388.AQWU01000033_gene1751	5.784e-26	113.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
LZS3_k127_1670833_30	927704.SELR_27260	9.155e-20	94.0	COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4H54R@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
LZS3_k127_1670833_11	240016.ABIZ01000001_gene1841	2.031e-94	315.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS3_k127_1840455_0	34007.IT40_00800	9.016e-295	923.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2PUKE@265|Paracoccus	28211|Alphaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
LZS3_k127_1840455_1	251221.35211061	1.286e-126	430.0	COG2374@1|root,COG2374@2|Bacteria,1GHB9@1117|Cyanobacteria	1117|Cyanobacteria	G	Endonuclease Exonuclease phosphatase	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	DUF5017,Endonuclease_1,Exo_endo_phos,TIG
LZS3_k127_1840455_5	378806.STAUR_1873	1.014e-09	66.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,42WCG@68525|delta/epsilon subdivisions,2WS1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
LZS3_k127_1840455_3	290397.Adeh_3932	1.014e-43	162.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,42VVC@68525|delta/epsilon subdivisions,2WRH9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
LZS3_k127_1840455_4	880073.Calab_3104	2.768e-13	75.0	COG2356@1|root,COG4447@1|root,COG2356@2|Bacteria,COG4447@2|Bacteria,2NRJS@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease I	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Endonuclease_1,FlgD_ig,LTD,PSII_BNR
LZS3_k127_187081_20	926549.KI421517_gene4076	2.223e-53	199.0	28JU1@1|root,2Z9J4@2|Bacteria,4NV4K@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
LZS3_k127_187081_36	471854.Dfer_0723	7.298e-12	79.0	COG3210@1|root,COG4886@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,4NTNN@976|Bacteroidetes,47K8B@768503|Cytophagia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
LZS3_k127_187081_28	1379698.RBG1_1C00001G1831	1.385e-29	137.0	COG2706@1|root,COG4733@1|root,COG2706@2|Bacteria,COG4733@2|Bacteria,2NR81@2323|unclassified Bacteria	2|Bacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	PKD,VCBS
LZS3_k127_187081_35	880073.Calab_2214	1.345e-18	101.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	-
LZS3_k127_187081_3	246194.CHY_1607	1.194e-201	649.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,24C0I@186801|Clostridia,42HWH@68295|Thermoanaerobacterales	186801|Clostridia	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_187081_40	44689.DDB0206401	1.227e-06	59.0	2EVG7@1|root,2SXFY@2759|Eukaryota,3XDMH@554915|Amoebozoa	554915|Amoebozoa	S	A Receptor for Ubiquitination Targets	-	-	-	-	-	-	-	-	-	-	-	-	F-box-like
LZS3_k127_187081_6	986075.CathTA2_3094	5.787e-154	495.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli	91061|Bacilli	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_187081_19	1227499.C493_03345	1.72e-58	231.0	COG3119@1|root,arCOG02787@2157|Archaea,2XUWX@28890|Euryarchaeota,23S64@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_187081_2	1125863.JAFN01000001_gene833	1.919e-259	822.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
LZS3_k127_187081_27	1230338.MOMA_06461	9.53e-30	129.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,1RP3P@1236|Gammaproteobacteria,3NRGK@468|Moraxellaceae	1236|Gammaproteobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
LZS3_k127_187081_9	204669.Acid345_4390	1.105e-117	413.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y69R@57723|Acidobacteria,2JKIQ@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
LZS3_k127_187081_8	398767.Glov_0364	1.881e-122	412.0	COG0668@1|root,COG0668@2|Bacteria,1N66N@1224|Proteobacteria,42MXP@68525|delta/epsilon subdivisions,2WMI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS3_k127_187081_11	247490.KSU1_C0449	5.589e-99	349.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_187081_41	518766.Rmar_1484	1.414e-05	58.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Kelch_4
LZS3_k127_187081_16	521674.Plim_3882	2.002e-60	226.0	COG1541@1|root,COG1541@2|Bacteria,2IZEM@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
LZS3_k127_187081_23	861299.J421_0735	1.081e-36	150.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_0735|-	S	peptidyl-tyrosine sulfation	-	-	-	ko:K13992	-	-	-	-	ko00000,ko00194	-	-	-	-
LZS3_k127_187081_30	983544.Lacal_1507	8.176e-27	116.0	COG1510@1|root,COG1510@2|Bacteria,4NQPD@976|Bacteroidetes,1I39Q@117743|Flavobacteriia	976|Bacteroidetes	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,MarR_2,TrmB
LZS3_k127_187081_25	1336249.JADW01000003_gene3903	2.82e-36	153.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,4B8J7@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS3_k127_187081_31	161528.ED21_31754	2.58e-26	123.0	COG1538@1|root,COG1538@2|Bacteria,1QIFM@1224|Proteobacteria,2VG3X@28211|Alphaproteobacteria,2KE19@204457|Sphingomonadales	204457|Sphingomonadales	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
LZS3_k127_187081_14	880073.Calab_1258	6.169e-71	251.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_D23
LZS3_k127_187081_0	883078.HMPREF9695_02417	0.0	1276.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,3JRVP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
LZS3_k127_187081_1	511051.CSE_05010	9.002e-294	922.0	COG0021@1|root,COG0021@2|Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N,XFP,XFP_N
LZS3_k127_187081_13	713587.THITH_12650	1.413e-75	264.0	COG0189@1|root,COG0189@2|Bacteria,1P1RY@1224|Proteobacteria	1224|Proteobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_187081_18	1121106.JQKB01000011_gene361	6.955e-59	214.0	COG1028@1|root,COG1028@2|Bacteria,1R413@1224|Proteobacteria,2TW0W@28211|Alphaproteobacteria,2JSIE@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_187081_24	1121124.JNIX01000008_gene2546	2.192e-36	160.0	COG0460@1|root,COG0527@1|root,COG0460@2|Bacteria,COG0527@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,2KFVZ@204458|Caulobacterales	204458|Caulobacterales	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Homoserine_dh,NAD_binding_3
LZS3_k127_187081_12	1192034.CAP_3187	7.689e-93	327.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2YVCC@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
LZS3_k127_187081_39	861299.J421_6027	3.494e-07	61.0	2EB5B@1|root,33561@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_187081_34	1353276.JADR01000008_gene859	1.435e-22	111.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,1I19I@117743|Flavobacteriia	976|Bacteroidetes	T	GAF domain-containing protein	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
LZS3_k127_187081_17	316067.Geob_3809	4.676e-60	216.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,42RI1@68525|delta/epsilon subdivisions,2WNBG@28221|Deltaproteobacteria,43UTQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
LZS3_k127_187081_15	290397.Adeh_0636	1.59e-64	239.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YXY8@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_187081_33	1521187.JPIM01000057_gene2573	6.138e-23	105.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_187081_4	1210884.HG799462_gene8307	2.174e-156	500.0	COG0798@1|root,COG0798@2|Bacteria,2IY8H@203682|Planctomycetes	203682|Planctomycetes	P	COG0798 Arsenite efflux pump ACR3 and related	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
LZS3_k127_187081_10	247490.KSU1_C0449	3.084e-102	354.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_187081_38	880073.Calab_0041	1.938e-09	70.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
LZS3_k127_187081_32	644282.Deba_2269	3.391e-23	103.0	COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
LZS3_k127_187081_5	572547.Amico_0060	1.581e-155	499.0	COG0701@1|root,COG0701@2|Bacteria,3TAPB@508458|Synergistetes	508458|Synergistetes	S	Permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
LZS3_k127_187081_29	1499967.BAYZ01000050_gene2875	1.604e-28	125.0	2DPAK@1|root,33193@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_187081_21	575540.Isop_2575	3.214e-53	202.0	COG0785@1|root,COG0785@2|Bacteria,2J2ZI@203682|Planctomycetes	203682|Planctomycetes	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
LZS3_k127_187081_26	1463825.JNXC01000009_gene1539	3.053e-36	144.0	COG1247@1|root,COG1247@2|Bacteria,2I359@201174|Actinobacteria,4EEB3@85010|Pseudonocardiales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
LZS3_k127_187081_7	1379270.AUXF01000002_gene1241	3.504e-136	463.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1ZTK4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
LZS3_k127_187081_22	595460.RRSWK_04777	2.668e-44	170.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
LZS3_k127_187081_37	1229172.JQFA01000002_gene2423	4.707e-10	72.0	COG5555@1|root,COG5555@2|Bacteria,1GG4X@1117|Cyanobacteria	1117|Cyanobacteria	N	Thiol-activated cytolysin beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiol_cytolys_C
LZS3_k127_1875034_7	929556.Solca_4357	0.0003254	48.0	2C802@1|root,332EH@2|Bacteria,4NR3G@976|Bacteroidetes,1ISY9@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
LZS3_k127_1875034_3	1132855.KB913035_gene1464	8.408e-66	247.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,2VR92@28216|Betaproteobacteria,2KP3X@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
LZS3_k127_1875034_2	1173264.KI913949_gene362	4.325e-144	468.0	COG1252@1|root,COG1252@2|Bacteria,1G20T@1117|Cyanobacteria,1H80B@1150|Oscillatoriales	1117|Cyanobacteria	C	NADH dehydrogenase, FAD-containing subunit	ndbA	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS3_k127_1875034_6	937777.Deipe_3025	4.934e-05	54.0	COG1295@1|root,COG1295@2|Bacteria,1WMJT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM YihY family protein (not ribonuclease BN)	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
LZS3_k127_1875034_1	1306947.ARQD01000005_gene53	9.031e-163	517.0	COG0208@1|root,COG0208@2|Bacteria,2NQ0T@2323|unclassified Bacteria	2|Bacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iJN746.PP_1177	Ribonuc_red_sm
LZS3_k127_1875034_0	1123242.JH636435_gene2200	2.164e-314	988.0	COG0209@1|root,COG0209@2|Bacteria,2IWU1@203682|Planctomycetes	203682|Planctomycetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
LZS3_k127_1875034_4	880073.Calab_2774	1.814e-53	196.0	COG0325@1|root,COG0325@2|Bacteria,2NPEW@2323|unclassified Bacteria	2|Bacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
LZS3_k127_1875034_5	290397.Adeh_1311	9.453e-23	109.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WS27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
LZS3_k127_1934882_1	471852.Tcur_3455	7.18e-72	255.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4EI19@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
LZS3_k127_1934882_0	243365.CV_3432	2.139e-131	429.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,2VQV7@28216|Betaproteobacteria,2KTR5@206351|Neisseriales	206351|Neisseriales	E	Spore germination protein	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS3_k127_200578_3	1379698.RBG1_1C00001G0592	8.041e-14	72.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
LZS3_k127_200578_2	1227739.Hsw_1667	1.096e-28	131.0	COG1293@1|root,COG1293@2|Bacteria,4NGP5@976|Bacteroidetes,47M54@768503|Cytophagia	976|Bacteroidetes	K	Fibronectin-binding protein A N-terminus (FbpA)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
LZS3_k127_200578_0	264732.Moth_0890	2.165e-57	211.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,42EU9@68295|Thermoanaerobacterales	186801|Clostridia	S	domain protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
LZS3_k127_200578_1	1123392.AQWL01000004_gene2844	4.512e-42	173.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,1KSR1@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Guanylate kinase homologues.	-	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
LZS3_k127_2092674_1	379066.GAU_3833	4.645e-57	207.0	COG0631@1|root,COG0631@2|Bacteria,1ZSYG@142182|Gemmatimonadetes	2|Bacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
LZS3_k127_2092674_0	1379698.RBG1_1C00001G1613	1.31e-76	271.0	COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria	2|Bacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,PEGA,Pkinase
LZS3_k127_2271999_1	204669.Acid345_3980	3.314e-56	225.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_8
LZS3_k127_2313930_18	861299.J421_0584	3.647e-92	316.0	COG0308@1|root,COG0308@2|Bacteria,1ZT68@142182|Gemmatimonadetes	2|Bacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
LZS3_k127_2313930_1	502025.Hoch_5309	1.882e-247	776.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
LZS3_k127_2313930_36	880073.Calab_0921	1.447e-19	104.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_2313930_38	1453500.AT05_09355	5.637e-15	89.0	28KE7@1|root,2ZA0G@2|Bacteria,4P0D4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2313930_20	1049564.TevJSym_ar00200	3.149e-79	273.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1J613@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane protein, hemolysin III homolog	yqfA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
LZS3_k127_2313930_23	1307759.JOMJ01000003_gene2091	1.397e-65	236.0	COG1192@1|root,COG1192@2|Bacteria,1Q9Y4@1224|Proteobacteria,42ZVG@68525|delta/epsilon subdivisions,2WV5I@28221|Deltaproteobacteria,2MFX2@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
LZS3_k127_2313930_39	740709.A10D4_11339	0.0003502	49.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,2QG84@267893|Idiomarinaceae	1236|Gammaproteobacteria	P	subunit of a heme lyase	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
LZS3_k127_2313930_12	448385.sce6263	1.119e-112	379.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,438CB@68525|delta/epsilon subdivisions,2X3MN@28221|Deltaproteobacteria,2YWIY@29|Myxococcales	28221|Deltaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	-
LZS3_k127_2313930_2	404589.Anae109_3731	1.64e-239	770.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
LZS3_k127_2313930_16	1254432.SCE1572_02795	1.192e-100	349.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS3_k127_2313930_8	1254432.SCE1572_02795	1.015e-125	421.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
LZS3_k127_2313930_24	1385935.N836_19200	5.543e-65	246.0	COG0438@1|root,COG0438@2|Bacteria,1G1ED@1117|Cyanobacteria,1HH55@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_2313930_5	1049564.TevJSym_at00210	1.395e-144	481.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1J58Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS3_k127_2313930_27	1122243.KB903770_gene615	7.807e-52	192.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1S222@1236|Gammaproteobacteria,3NKAW@468|Moraxellaceae	1236|Gammaproteobacteria	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
LZS3_k127_2313930_11	518766.Rmar_2384	4.391e-116	392.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS3_k127_2313930_13	312309.VF_A1107	2.924e-106	365.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1XVNX@135623|Vibrionales	135623|Vibrionales	M	Small-conductance mechanosensitive channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
LZS3_k127_2313930_30	945713.IALB_1400	7.49e-30	139.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	rtxA	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	ASH,CBM_2,Calx-beta,DUF4214,FlgD_ig,HemolysinCabind,SdrD_B
LZS3_k127_2313930_26	1120953.AUBH01000004_gene2977	9.047e-58	229.0	2EXJW@1|root,33QVY@2|Bacteria,1QSMJ@1224|Proteobacteria,1SK5H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2313930_29	1116375.VEJY3_02945	9.105e-33	138.0	2BN4A@1|root,32GR8@2|Bacteria,1RHQ4@1224|Proteobacteria,1S86P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2313930_9	290397.Adeh_3188	4.031e-123	419.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955	-	-	-	-	ko00000	-	-	-	Big_4,FTP,Laminin_G_3,PA,Peptidase_M36
LZS3_k127_2313930_37	880073.Calab_2081	4.91e-18	99.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_2313930_14	448385.sce0941	3.093e-102	341.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,4307J@68525|delta/epsilon subdivisions,2WV6F@28221|Deltaproteobacteria,2YVCQ@29|Myxococcales	28221|Deltaproteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_2313930_3	1408473.JHXO01000011_gene3210	5.253e-206	665.0	COG0421@1|root,COG0421@2|Bacteria,4NTHI@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2313930_33	1379698.RBG1_1C00001G0632	9.504e-23	108.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS3_k127_2313930_15	1121920.AUAU01000005_gene973	1.362e-101	342.0	COG1734@1|root,COG2208@1|root,COG1734@2|Bacteria,COG2208@2|Bacteria,3Y4RV@57723|Acidobacteria	57723|Acidobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
LZS3_k127_2313930_31	1121920.AUAU01000005_gene974	8.539e-30	124.0	COG2318@1|root,COG2318@2|Bacteria,3Y5VC@57723|Acidobacteria	57723|Acidobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS3_k127_2313930_28	926560.KE387027_gene964	4.86e-45	171.0	COG5516@1|root,COG5516@2|Bacteria,1WMR5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
LZS3_k127_2313930_19	215803.DB30_0760	6.941e-86	291.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,42PPN@68525|delta/epsilon subdivisions,2WK8S@28221|Deltaproteobacteria,2Z1ED@29|Myxococcales	28221|Deltaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
LZS3_k127_2313930_32	861299.J421_4375	1.338e-24	112.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_2313930_4	489825.LYNGBM3L_52760	1.704e-193	624.0	COG2304@1|root,COG2304@2|Bacteria,1G3PE@1117|Cyanobacteria,1H7T7@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
LZS3_k127_2313930_21	1192034.CAP_7219	1.204e-71	252.0	COG2172@1|root,COG2197@1|root,COG2172@2|Bacteria,COG2197@2|Bacteria,1PGJ3@1224|Proteobacteria,4315J@68525|delta/epsilon subdivisions,2WWDE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,Response_reg
LZS3_k127_2313930_34	58123.JOFJ01000018_gene4321	5.317e-20	104.0	COG1073@1|root,COG1073@2|Bacteria,2H036@201174|Actinobacteria,4EH1R@85012|Streptosporangiales	201174|Actinobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4,Peptidase_S9
LZS3_k127_2313930_6	290397.Adeh_3188	5.814e-128	433.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955	-	-	-	-	ko00000	-	-	-	Big_4,FTP,Laminin_G_3,PA,Peptidase_M36
LZS3_k127_2313930_35	880073.Calab_0041	1.023e-19	104.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
LZS3_k127_2313930_7	1121920.AUAU01000004_gene751	1.49e-126	417.0	COG1748@1|root,COG1748@2|Bacteria,3Y84N@57723|Acidobacteria	57723|Acidobacteria	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
LZS3_k127_2313930_10	1123228.AUIH01000007_gene2581	2.684e-116	387.0	COG0667@1|root,COG0667@2|Bacteria,1PDY4@1224|Proteobacteria,1RQYV@1236|Gammaproteobacteria,1XIDK@135619|Oceanospirillales	135619|Oceanospirillales	C	Aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_2313930_22	215803.DB30_6542	2.371e-66	234.0	COG0500@1|root,COG2226@2|Bacteria,1RC36@1224|Proteobacteria,42UDA@68525|delta/epsilon subdivisions,2WQHW@28221|Deltaproteobacteria,2YV8X@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
LZS3_k127_2313930_0	690850.Desaf_3477	0.0	1113.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,42MZ4@68525|delta/epsilon subdivisions,2WJPB@28221|Deltaproteobacteria,2MABY@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
LZS3_k127_2313930_25	469383.Cwoe_2725	6.178e-60	210.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,4CTCG@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric uptake regulator family	-	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
LZS3_k127_2313930_17	219305.MCAG_03369	6.134e-98	325.0	2CA5R@1|root,2Z81H@2|Bacteria,2GM6V@201174|Actinobacteria,4DAFJ@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2361915_1	443143.GM18_3886	1.003e-146	478.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS3_k127_2361915_6	370438.PTH_1859	2.135e-68	243.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,261EW@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
LZS3_k127_2361915_14	391625.PPSIR1_01342	2.312e-11	73.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,2YVR5@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
LZS3_k127_2361915_3	1379281.AVAG01000035_gene1761	4.324e-105	355.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2M85X@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
LZS3_k127_2361915_4	518766.Rmar_2697	2.734e-97	334.0	COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,1FIJS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
LZS3_k127_2361915_7	593750.Metfor_1649	3.614e-33	146.0	COG0457@1|root,arCOG03042@1|root,arCOG03032@2157|Archaea,arCOG03038@2157|Archaea,arCOG03042@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAN4@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS3_k127_2361915_11	521098.Aaci_1329	2.182e-18	89.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4I3V5@91061|Bacilli,278KK@186823|Alicyclobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
LZS3_k127_2361915_0	1121468.AUBR01000026_gene2924	2.249e-171	561.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,42ES5@68295|Thermoanaerobacterales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
LZS3_k127_2361915_2	1173026.Glo7428_1703	6.062e-116	392.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G0MX@1117|Cyanobacteria	1117|Cyanobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
LZS3_k127_2361915_10	1107311.Q767_03615	2.079e-20	98.0	28N4A@1|root,2ZB9T@2|Bacteria,4PJ7Q@976|Bacteroidetes,1ID5S@117743|Flavobacteriia,2NXF4@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
LZS3_k127_2361915_8	1121904.ARBP01000028_gene1685	2.244e-26	117.0	COG3047@1|root,COG3047@2|Bacteria,4NWCT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2361915_12	1379270.AUXF01000006_gene311	1.896e-17	92.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
LZS3_k127_2361915_9	1499967.BAYZ01000074_gene2082	1.656e-21	106.0	COG2172@1|root,COG2204@1|root,COG2172@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	2.7.11.1,2.7.7.65	ko:K02488,ko:K04757	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	HATPase_c,HATPase_c_2,HisKA,Response_reg
LZS3_k127_2361915_15	555793.WSK_3886	1.556e-08	67.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TWH9@28211|Alphaproteobacteria,2KEEK@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
LZS3_k127_2361915_5	391625.PPSIR1_33044	2.292e-69	249.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
LZS3_k127_2432903_3	886293.Sinac_4765	2.412e-55	218.0	COG3210@1|root,COG4733@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,2J50K@203682|Planctomycetes	203682|Planctomycetes	U	Pkd domain containing protein	-	-	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	-
LZS3_k127_2432903_5	880073.Calab_1769	5.384e-20	106.0	COG5563@1|root,COG5563@2|Bacteria	2|Bacteria	-	-	CP_1072	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
LZS3_k127_2432903_1	1192034.CAP_2122	6.471e-87	323.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_2432903_4	1379698.RBG1_1C00001G1831	1.552e-26	128.0	COG2706@1|root,COG4733@1|root,COG2706@2|Bacteria,COG4733@2|Bacteria,2NR81@2323|unclassified Bacteria	2|Bacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	PKD,VCBS
LZS3_k127_2432903_6	459349.CLOAM1520	3.414e-14	87.0	COG4412@1|root,COG4412@2|Bacteria,2NQZW@2323|unclassified Bacteria	2|Bacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,W_rich_C,fn3
LZS3_k127_2432903_0	296591.Bpro_3213	1.955e-157	510.0	COG0668@1|root,COG0668@2|Bacteria,1MXH4@1224|Proteobacteria,2VM0E@28216|Betaproteobacteria,4AJT7@80864|Comamonadaceae	28216|Betaproteobacteria	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
LZS3_k127_2526289_8	926692.AZYG01000034_gene2382	9.82e-73	261.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WACP@53433|Halanaerobiales	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
LZS3_k127_2526289_15	521045.Kole_0745	6.381e-41	157.0	COG0242@1|root,COG0242@2|Bacteria,2GD55@200918|Thermotogae	200918|Thermotogae	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
LZS3_k127_2526289_26	545695.TREAZ_3376	7.688e-20	93.0	COG1862@1|root,COG1862@2|Bacteria,2J8D6@203691|Spirochaetes	203691|Spirochaetes	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
LZS3_k127_2526289_4	880073.Calab_3729	1.049e-117	414.0	COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
LZS3_k127_2526289_5	880073.Calab_2195	1.949e-111	379.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
LZS3_k127_2526289_20	880073.Calab_2196	6.883e-31	136.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I
LZS3_k127_2526289_31	795666.MW7_2145	4.213e-10	74.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,1KD2G@119060|Burkholderiaceae	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
LZS3_k127_2526289_6	270374.MELB17_11273	1.212e-96	327.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,464VM@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
LZS3_k127_2526289_17	290397.Adeh_3934	8.971e-39	159.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS3_k127_2526289_3	880073.Calab_2591	2.681e-123	404.0	COG2255@1|root,COG2255@2|Bacteria,2NNUG@2323|unclassified Bacteria	2|Bacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
LZS3_k127_2526289_18	748658.KB907313_gene2166	1.388e-38	153.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
LZS3_k127_2526289_19	1121923.GPUN_1564	3.2e-37	155.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,466I2@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
LZS3_k127_2526289_7	1158318.ATXC01000001_gene573	6.274e-90	302.0	COG0217@1|root,COG0217@2|Bacteria,2G3N5@200783|Aquificae	200783|Aquificae	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
LZS3_k127_2526289_1	56780.SYN_02930	1.49e-186	605.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2MR6X@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Elongation factor Tu domain 2	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS3_k127_2526289_32	1304872.JAGC01000003_gene3036	1.153e-09	70.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria,2MDU0@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS3_k127_2526289_34	1444310.JANV01000142_gene3763	5.418e-06	57.0	2EJ6V@1|root,33CY2@2|Bacteria,1VPDN@1239|Firmicutes,4HS8D@91061|Bacilli,1ZIQW@1386|Bacillus	91061|Bacilli	S	Yip1 domain	yknW	-	-	-	-	-	-	-	-	-	-	-	Yip1
LZS3_k127_2526289_13	290318.Cvib_0237	2.228e-42	170.0	COG0438@1|root,COG0438@2|Bacteria,1FE7C@1090|Chlorobi	1090|Chlorobi	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
LZS3_k127_2526289_24	1089553.Tph_c02290	4.876e-22	109.0	COG0438@1|root,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,25EAY@186801|Clostridia,42G5D@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_2526289_22	237368.SCABRO_00129	2.359e-26	121.0	COG0265@1|root,COG0265@2|Bacteria,2IY5I@203682|Planctomycetes	203682|Planctomycetes	O	PDZ domain (Also known as DHR	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_2526289_28	1348114.OM33_15960	4e-16	93.0	COG3307@1|root,COG3307@2|Bacteria,1RBK5@1224|Proteobacteria,1S2Y8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS3_k127_2526289_16	1379698.RBG1_1C00001G1536	4.266e-39	161.0	COG3206@1|root,COG3206@2|Bacteria,2NQ0K@2323|unclassified Bacteria	2|Bacteria	M	Chain length determinant protein	-	-	3.1.21.3	ko:K01153,ko:K05789,ko:K07011,ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01005,ko02000,ko02048	8.A.3.1	-	-	GNVR,Wzz
LZS3_k127_2526289_10	218284.CCDN010000008_gene4081	2.627e-64	235.0	COG1215@1|root,COG1215@2|Bacteria,1TPY9@1239|Firmicutes,4HF9W@91061|Bacilli,1ZGWH@1386|Bacillus	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_2526289_35	366649.XFF4834R_chr11870	6.768e-06	59.0	COG2199@1|root,COG3292@1|root,COG2199@2|Bacteria,COG3292@2|Bacteria,1RGCV@1224|Proteobacteria,1T227@1236|Gammaproteobacteria,1XD7F@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
LZS3_k127_2526289_11	880073.Calab_0150	2.54e-55	207.0	COG1597@1|root,COG1597@2|Bacteria,2NQYH@2323|unclassified Bacteria	2|Bacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
LZS3_k127_2526289_23	378806.STAUR_5747	2.69e-23	115.0	COG1287@1|root,COG1287@2|Bacteria,1PCK3@1224|Proteobacteria,432KV@68525|delta/epsilon subdivisions,2WXVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_2526289_14	1191523.MROS_0145	8.634e-42	165.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
LZS3_k127_2526289_9	1382306.JNIM01000001_gene1938	1.541e-67	252.0	COG0846@1|root,COG0846@2|Bacteria	2|Bacteria	K	NAD+ binding	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
LZS3_k127_2526289_33	1297742.A176_00262	6.951e-07	63.0	COG1470@1|root,COG2885@1|root,COG4719@1|root,COG1470@2|Bacteria,COG2885@2|Bacteria,COG4719@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
LZS3_k127_2526289_30	656024.FsymDg_2329	4.515e-12	79.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS3_k127_2526289_25	1307759.JOMJ01000004_gene2870	4.218e-21	107.0	COG1807@1|root,COG1807@2|Bacteria,1RJ20@1224|Proteobacteria,43BAJ@68525|delta/epsilon subdivisions,2X6PS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2526289_0	1120973.AQXL01000117_gene355	1.028e-222	702.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HBS1@91061|Bacilli,27963@186823|Alicyclobacillaceae	91061|Bacilli	C	Aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
LZS3_k127_2526289_21	1121381.JNIV01000121_gene906	3.31e-30	125.0	COG0824@1|root,COG0824@2|Bacteria,1WKEF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
LZS3_k127_2526289_27	266117.Rxyl_0794	4.503e-19	95.0	COG1254@1|root,COG1254@2|Bacteria,2IT6J@201174|Actinobacteria,4CTJ9@84995|Rubrobacteria	84995|Rubrobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
LZS3_k127_2526289_29	671143.DAMO_3152	1.007e-12	73.0	COG1371@1|root,COG1371@2|Bacteria,2NPX9@2323|unclassified Bacteria	2|Bacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
LZS3_k127_2526289_2	679926.Mpet_1361	3.912e-184	597.0	COG0171@1|root,COG0388@1|root,arCOG00062@2157|Archaea,arCOG00069@2157|Archaea,2XUJI@28890|Euryarchaeota,2NBHN@224756|Methanomicrobia	224756|Methanomicrobia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	-	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
LZS3_k127_2526289_12	323261.Noc_2060	1.724e-50	188.0	COG2345@1|root,COG2345@2|Bacteria,1RDXT@1224|Proteobacteria,1S4DW@1236|Gammaproteobacteria,1X1P9@135613|Chromatiales	135613|Chromatiales	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
LZS3_k127_277667_3	748658.KB907313_gene2172	1.325e-20	108.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1WVZJ@135613|Chromatiales	135613|Chromatiales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS3_k127_277667_0	243231.GSU2357	4.835e-87	299.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,43C4Y@68525|delta/epsilon subdivisions,2X7FA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS3_k127_277667_1	935863.AWZR01000007_gene259	4.725e-74	257.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1X3XJ@135614|Xanthomonadales	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS3_k127_277667_2	1434929.X946_4169	3.298e-39	160.0	COG0454@1|root,COG0454@2|Bacteria,1QTZ4@1224|Proteobacteria,2VSAH@28216|Betaproteobacteria,1K7CM@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_277667_6	522373.Smlt1846	6.763e-05	47.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1X5HK@135614|Xanthomonadales	135614|Xanthomonadales	L	Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
LZS3_k127_277667_4	1123247.AUIJ01000007_gene2840	1.582e-11	67.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2TTBD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
LZS3_k127_2955370_6	1210884.HG799464_gene11148	1.508e-68	252.0	COG2206@1|root,COG2206@2|Bacteria,2IWTK@203682|Planctomycetes	203682|Planctomycetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,HD
LZS3_k127_2955370_0	269799.Gmet_1297	2.708e-269	865.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,43SXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
LZS3_k127_2955370_8	925409.KI911562_gene389	4.886e-33	136.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
LZS3_k127_2955370_10	307480.IW16_18270	9.912e-24	107.0	COG2318@1|root,COG2318@2|Bacteria,4P4W2@976|Bacteroidetes,1I9ND@117743|Flavobacteriia,3ZRRW@59732|Chryseobacterium	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2955370_1	401526.TcarDRAFT_1649	9.76e-179	577.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,4H33G@909932|Negativicutes	909932|Negativicutes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
LZS3_k127_2955370_7	1231336.L248_0038	4.549e-52	206.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,3F43E@33958|Lactobacillaceae	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
LZS3_k127_2955370_5	335543.Sfum_1414	1.527e-82	299.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS3_k127_2955370_4	1123376.AUIU01000014_gene532	2.333e-94	320.0	COG0601@1|root,COG0601@2|Bacteria,3J12R@40117|Nitrospirae	40117|Nitrospirae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS3_k127_2955370_3	335543.Sfum_1411	6.52e-110	377.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2MQ6I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
LZS3_k127_2955370_2	1379698.RBG1_1C00001G0513	3.094e-130	429.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
LZS3_k127_2955370_11	459349.CLOAM0164	3.37e-13	83.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
LZS3_k127_2955370_9	1047013.AQSP01000110_gene65	8.015e-27	128.0	COG1404@1|root,COG1404@2|Bacteria,2NP8X@2323|unclassified Bacteria	2|Bacteria	O	Subtilase family	apr	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
LZS3_k127_2955370_12	483219.LILAB_36270	1.782e-12	78.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS3_k127_2992816_13	378806.STAUR_0109	5.084e-35	135.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,42U1Z@68525|delta/epsilon subdivisions,2WQ05@28221|Deltaproteobacteria,2Z1RY@29|Myxococcales	28221|Deltaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_2992816_10	1191523.MROS_2221	7.02e-41	160.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950,ko:K09163	-	-	-	-	ko00000	-	-	-	HD
LZS3_k127_2992816_12	1242864.D187_001666	3.613e-35	152.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
LZS3_k127_2992816_16	330214.NIDE4023	2.174e-27	117.0	COG1959@1|root,COG1959@2|Bacteria,3J18M@40117|Nitrospirae	40117|Nitrospirae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS3_k127_2992816_11	1123248.KB893316_gene4667	8.618e-37	146.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1ITAW@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
LZS3_k127_2992816_5	161934.XP_010667950.1	3.415e-103	350.0	COG4638@1|root,2QQJW@2759|Eukaryota,37M74@33090|Viridiplantae,3GARM@35493|Streptophyta	35493|Streptophyta	P	choline monooxygenase	-	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
LZS3_k127_2992816_0	1229909.NSED_07410	2.72e-229	732.0	COG0189@1|root,COG0624@1|root,arCOG01107@2157|Archaea,arCOG01589@2157|Archaea	2157|Archaea	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	rimK	-	3.4.17.11,3.5.1.18,6.3.2.2,6.3.2.4	ko:K01295,ko:K01439,ko:K01919,ko:K01921,ko:K05844	ko00270,ko00300,ko00473,ko00480,ko00550,ko01100,ko01120,ko01230,ko01502,map00270,map00300,map00473,map00480,map00550,map01100,map01120,map01230,map01502	M00016,M00118	R00894,R01150,R02734,R10993	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03009	-	-	-	M20_dimer,Peptidase_M20,RimK
LZS3_k127_2992816_2	123214.PERMA_1251	2.347e-177	572.0	COG0405@1|root,COG0405@2|Bacteria,2G3M5@200783|Aquificae	2|Bacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
LZS3_k127_2992816_6	123214.PERMA_1250	1.101e-57	214.0	COG3741@1|root,COG3741@2|Bacteria	2|Bacteria	E	N-formylglutamate amidohydrolase	-	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
LZS3_k127_2992816_8	1128421.JAGA01000002_gene1502	1.415e-48	186.0	COG0611@1|root,COG0611@2|Bacteria,2NP8J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU05900	AIRS,AIRS_C
LZS3_k127_2992816_20	1303518.CCALI_00008	4.132e-09	66.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS3_k127_2992816_1	1124780.ANNU01000016_gene1823	1.775e-194	636.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes,47M3W@768503|Cytophagia	976|Bacteroidetes	E	Leukotriene A4 hydrolase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
LZS3_k127_2992816_7	1157708.KB907453_gene4049	9.919e-54	196.0	COG0622@1|root,COG0622@2|Bacteria,1RGUN@1224|Proteobacteria,2VT3X@28216|Betaproteobacteria,4AETS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
LZS3_k127_2992816_17	1501230.ET33_05505	1.641e-25	111.0	COG2318@1|root,COG2318@2|Bacteria,1VB99@1239|Firmicutes,4HNES@91061|Bacilli,26ZFK@186822|Paenibacillaceae	91061|Bacilli	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DinB
LZS3_k127_2992816_15	1237149.C900_03285	4.139e-30	127.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_2992816_18	1144275.COCOR_00143	8.659e-12	75.0	COG3795@1|root,COG3795@2|Bacteria,1NJ4J@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
LZS3_k127_2992816_4	1142394.PSMK_18320	8.814e-144	471.0	COG3211@1|root,COG3211@2|Bacteria,2IXU8@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
LZS3_k127_2992816_9	595460.RRSWK_01550	8.006e-48	190.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
LZS3_k127_2992816_3	96561.Dole_2292	1.122e-156	515.0	COG0025@1|root,COG0569@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,1QTUE@1224|Proteobacteria,43BRM@68525|delta/epsilon subdivisions,2WM4A@28221|Deltaproteobacteria,2MHXR@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger,TrkA_N
LZS3_k127_2992816_14	1121104.AQXH01000001_gene1649	8.685e-34	137.0	COG1595@1|root,COG1595@2|Bacteria,4NMIY@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
LZS3_k127_2992816_19	330214.NIDE1746	1.328e-11	76.0	COG4372@1|root,COG5343@1|root,COG4372@2|Bacteria,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	LZ_Tnp_IS66,RskA,zf-HC2
LZS3_k127_2996674_37	880073.Calab_0921	5.23e-23	107.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_2996674_38	861299.J421_3007	6.646e-23	102.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2996674_26	1120999.JONM01000024_gene3089	9.911e-42	163.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,2VSG8@28216|Betaproteobacteria,2KRBH@206351|Neisseriales	206351|Neisseriales	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
LZS3_k127_2996674_2	880073.Calab_1878	3.387e-163	524.0	2CD20@1|root,2Z7SQ@2|Bacteria,2NNUF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2996674_47	1499967.BAYZ01000154_gene1499	0.0003507	53.0	COG0457@1|root,COG0457@2|Bacteria,2NPK1@2323|unclassified Bacteria	2|Bacteria	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_1,TPR_11,TPR_2,TPR_8
LZS3_k127_2996674_11	880073.Calab_0677	6.022e-86	321.0	COG1196@1|root,COG1196@2|Bacteria,2NNSS@2323|unclassified Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2996674_20	1379698.RBG1_1C00001G0347	3.79e-65	230.0	COG1657@1|root,COG1657@2|Bacteria,2NP7R@2323|unclassified Bacteria	2|Bacteria	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159,Prenyltrans
LZS3_k127_2996674_41	880073.Calab_0187	5.006e-13	80.0	COG1747@1|root,COG4797@1|root,COG1747@2|Bacteria,COG4797@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N,SprA_N
LZS3_k127_2996674_30	290397.Adeh_1548	2.695e-33	144.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria,42UFZ@68525|delta/epsilon subdivisions,2WR5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2996674_29	290397.Adeh_4042	1.485e-34	147.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS3_k127_2996674_19	880072.Desac_0717	3.151e-65	257.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2MQRW@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
LZS3_k127_2996674_46	219305.MCAG_01337	0.0003415	49.0	COG1835@1|root,COG1835@2|Bacteria,2GMY0@201174|Actinobacteria,4DB02@85008|Micromonosporales	201174|Actinobacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2996674_43	1191523.MROS_0961	1.453e-09	69.0	COG3867@1|root,COG3867@2|Bacteria	2|Bacteria	G	arabinogalactan endo-1,4-beta-galactosidase activity	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
LZS3_k127_2996674_12	1232410.KI421418_gene2299	1.185e-80	278.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	SecD/SecF GG Motif	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS3_k127_2996674_5	1379698.RBG1_1C00001G0345	2.3e-126	423.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
LZS3_k127_2996674_14	321327.CYA_2272	8.904e-73	257.0	COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria,1GZKF@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
LZS3_k127_2996674_28	1123288.SOV_6c02050	1.801e-35	150.0	COG2861@1|root,COG2861@2|Bacteria,1V413@1239|Firmicutes,4H49M@909932|Negativicutes	909932|Negativicutes	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
LZS3_k127_2996674_24	338966.Ppro_2492	5.92e-50	188.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,43UBJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
LZS3_k127_2996674_8	903818.KI912268_gene2106	7.181e-101	340.0	COG0348@1|root,COG0348@2|Bacteria,3Y3H4@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
LZS3_k127_2996674_36	709991.Odosp_2217	1.395e-25	119.0	COG0526@1|root,COG1331@1|root,COG0526@2|Bacteria,COG1331@2|Bacteria,4PNW5@976|Bacteroidetes,2G0ZC@200643|Bacteroidia	976|Bacteroidetes	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
LZS3_k127_2996674_45	177437.HRM2_20280	4.644e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2MJAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
LZS3_k127_2996674_16	1120973.AQXL01000129_gene2458	9.597e-72	254.0	COG0702@1|root,COG0702@2|Bacteria,1TT3N@1239|Firmicutes,4HB09@91061|Bacilli	91061|Bacilli	GM	NAD(P)H-binding	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
LZS3_k127_2996674_13	338966.Ppro_1702	3.599e-76	276.0	COG0084@1|root,COG2896@1|root,COG0084@2|Bacteria,COG2896@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43TZ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Radical SAM domain protein	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
LZS3_k127_2996674_3	522772.Dacet_2363	2.442e-145	477.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,2GF31@200930|Deferribacteres	200930|Deferribacteres	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
LZS3_k127_2996674_9	398767.Glov_0655	2.294e-93	312.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
LZS3_k127_2996674_6	316067.Geob_2512	4.268e-114	379.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,43SCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS3_k127_2996674_32	1123355.JHYO01000005_gene912	3.11e-32	134.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,36YDT@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF502)	MA20_12960	-	-	-	-	-	-	-	-	-	-	-	DUF502
LZS3_k127_2996674_10	1379698.RBG1_1C00001G0467	2.951e-90	306.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
LZS3_k127_2996674_44	307480.IW16_25215	2.646e-09	64.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,1HZ70@117743|Flavobacteriia,3ZRDB@59732|Chryseobacterium	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_2996674_34	269799.Gmet_2319	6.057e-30	133.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43UA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
LZS3_k127_2996674_31	290397.Adeh_4042	3.174e-33	143.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS3_k127_2996674_22	1379698.RBG1_1C00001G0315	2.077e-55	209.0	COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria	2|Bacteria	D	Peptidase family M23	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
LZS3_k127_2996674_27	330214.NIDE3066	7.281e-38	153.0	COG2177@1|root,COG2177@2|Bacteria,3J18Q@40117|Nitrospirae	40117|Nitrospirae	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
LZS3_k127_2996674_17	880073.Calab_1944	3.557e-68	242.0	COG2884@1|root,COG2884@2|Bacteria,2NP95@2323|unclassified Bacteria	2|Bacteria	D	ATPases associated with a variety of cellular activities	ftsE	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
LZS3_k127_2996674_21	1288298.rosmuc_02890	3.04e-64	233.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,46PN3@74030|Roseovarius	28211|Alphaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
LZS3_k127_2996674_25	880073.Calab_0689	1.244e-42	175.0	COG0760@1|root,COG0760@2|Bacteria,2NPFB@2323|unclassified Bacteria	2|Bacteria	O	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
LZS3_k127_2996674_33	443143.GM18_0166	2.697e-31	136.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,43T4C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS3_k127_2996674_35	1379698.RBG1_1C00001G0706	2.561e-29	135.0	COG0760@1|root,COG0760@2|Bacteria,2NR9Y@2323|unclassified Bacteria	2|Bacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3,TPR_7
LZS3_k127_2996674_0	1121468.AUBR01000069_gene1116	2.258e-244	806.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
LZS3_k127_2996674_23	1089550.ATTH01000001_gene132	4.887e-50	201.0	COG1572@1|root,COG1572@2|Bacteria,4PM6M@976|Bacteroidetes,1FISJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB
LZS3_k127_2996674_7	1379698.RBG1_1C00001G0202	5.901e-102	340.0	COG1721@1|root,COG1721@2|Bacteria,2NP6B@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
LZS3_k127_2996674_39	1353529.M899_3029	1.369e-20	108.0	2FK3F@1|root,34BRJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_2996674_40	1304872.JAGC01000005_gene1702	1.199e-15	89.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42UIR@68525|delta/epsilon subdivisions,2WTWT@28221|Deltaproteobacteria,2MH0C@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_2996674_18	156889.Mmc1_2423	1.016e-67	234.0	COG0110@1|root,COG0110@2|Bacteria,1RDCP@1224|Proteobacteria,2TWW2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
LZS3_k127_2996674_1	313612.L8106_17742	9.115e-165	544.0	COG5360@1|root,COG5360@2|Bacteria,1G4V0@1117|Cyanobacteria	1117|Cyanobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
LZS3_k127_2996674_4	1379698.RBG1_1C00001G0201	4.512e-135	436.0	COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria	2|Bacteria	O	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS3_k127_3020698_46	501479.ACNW01000055_gene4167	7.865e-21	108.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,2U2JS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3020698_21	1157490.EL26_11510	2.163e-99	344.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,279NS@186823|Alicyclobacillaceae	91061|Bacilli	L	IMS family HHH motif	dinB	GO:0008150,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0050896	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
LZS3_k127_3020698_27	926560.KE387025_gene4131	3.776e-74	260.0	COG1028@1|root,COG1028@2|Bacteria,1WM2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_3020698_28	448385.sce3387	1.948e-70	261.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3020698_18	448385.sce3387	1.259e-119	406.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3020698_2	1122221.JHVI01000016_gene1611	1.501e-320	1000.0	COG0474@1|root,COG0474@2|Bacteria,1WICW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	pacL	-	3.6.3.6,3.6.3.8	ko:K01535,ko:K01537	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.2,3.A.3.3	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
LZS3_k127_3020698_19	383372.Rcas_4299	3.718e-103	345.0	COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS3_k127_3020698_63	1265505.ATUG01000001_gene4154	5.354e-06	55.0	293WK@1|root,2ZRBR@2|Bacteria,1PBHQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3020698_12	309807.SRU_0349	5.011e-154	520.0	COG5549@1|root,COG5549@2|Bacteria,4NEA0@976|Bacteroidetes	976|Bacteroidetes	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
LZS3_k127_3020698_6	1121904.ARBP01000005_gene4494	1.683e-177	601.0	COG3087@1|root,COG3087@2|Bacteria,4PNV5@976|Bacteroidetes	976|Bacteroidetes	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3020698_13	880073.Calab_2889	3.7e-150	503.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NQIQ@2323|unclassified Bacteria	2|Bacteria	E	X-Pro dipeptidyl-peptidase (S15 family)	dpp	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
LZS3_k127_3020698_52	861299.J421_0764	2.2e-16	92.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_3020698_61	574087.Acear_2131	1.403e-07	58.0	COG3205@1|root,COG3205@2|Bacteria	2|Bacteria	P	membrane	-	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2061
LZS3_k127_3020698_10	945713.IALB_2989	5.154e-162	541.0	COG0616@1|root,COG0616@2|Bacteria	2|Bacteria	OU	serine-type peptidase activity	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS3_k127_3020698_53	1499967.BAYZ01000069_gene1839	3.427e-16	91.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
LZS3_k127_3020698_8	1132855.KB913035_gene1498	4.394e-170	554.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,2KKTT@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
LZS3_k127_3020698_4	1121405.dsmv_2629	8.656e-218	690.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2MHYG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM malic	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
LZS3_k127_3020698_11	477184.KYC_21561	7.086e-158	511.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VI8J@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
LZS3_k127_3020698_14	926550.CLDAP_36880	5.238e-143	460.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS3_k127_3020698_0	926550.CLDAP_36890	0.0	1614.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS3_k127_3020698_26	247490.KSU1_C0449	3.003e-78	291.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_3020698_56	459349.CLOAM1781	7.644e-12	79.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K07282,ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11	-	-	HemolysinCabind,VCBS
LZS3_k127_3020698_41	247490.KSU1_C0449	1.859e-32	145.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_3020698_62	459349.CLOAM0583	2.017e-07	64.0	COG1404@1|root,COG1470@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,CarboxypepD_reg,DUF11,FlgD_ig,HYR,PKD,PPC,SLH,VCBS,fn3
LZS3_k127_3020698_36	1519464.HY22_13065	4.501e-36	148.0	COG0642@1|root,COG2205@2|Bacteria	1519464.HY22_13065|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3020698_3	1121918.ARWE01000001_gene3079	3.869e-228	728.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,43TQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
LZS3_k127_3020698_16	1121918.ARWE01000001_gene3080	1.046e-136	452.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,43TT3@69541|Desulfuromonadales	68525|delta/epsilon subdivisions	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
LZS3_k127_3020698_17	1121918.ARWE01000001_gene3081	3.33e-126	410.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,43V7G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
LZS3_k127_3020698_31	756067.MicvaDRAFT_5451	1.031e-50	208.0	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
LZS3_k127_3020698_47	880073.Calab_0921	1.632e-19	105.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_3020698_37	575788.VS_II0827	3.764e-35	140.0	COG3547@1|root,COG3547@2|Bacteria,1QJED@1224|Proteobacteria,1THDR@1236|Gammaproteobacteria,1XUEV@135623|Vibrionales	135623|Vibrionales	L	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
LZS3_k127_3020698_44	880073.Calab_0921	7.347e-24	108.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_3020698_9	1304874.JAFY01000002_gene661	3.182e-168	537.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_3020698_25	247490.KSU1_C0449	4.582e-83	304.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_3020698_60	1089548.KI783301_gene205	7.27e-09	69.0	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bprF	-	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8
LZS3_k127_3020698_57	1089550.ATTH01000001_gene1531	2.186e-11	78.0	COG2911@1|root,COG3210@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,4NTNN@976|Bacteroidetes	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
LZS3_k127_3020698_38	1137281.D778_01922	1.022e-34	154.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NF8H@976|Bacteroidetes,1IJ61@117743|Flavobacteriia	976|Bacteroidetes	E	Thermolysin metallopeptidase, catalytic domain	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF5011,FTP,Inhibitor_I69,MAM,Peptidase_C10,Peptidase_M14,Peptidase_M4,Peptidase_M43,Peptidase_M4_C,Reprolysin_4,fn3
LZS3_k127_3020698_54	269797.Mbar_A1995	1.781e-15	91.0	arCOG02516@1|root,arCOG02538@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,2Y7RK@28890|Euryarchaeota,2NBKX@224756|Methanomicrobia	2157|Archaea	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,He_PIG,PKD,PQQ_3,Peptidase_S8,S-layer
LZS3_k127_3020698_15	459349.CLOAM1312	3.181e-139	477.0	COG1404@1|root,COG1404@2|Bacteria,2NPDC@2323|unclassified Bacteria	2|Bacteria	O	Peptidase S8	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS3_k127_3020698_55	880073.Calab_3215	7.547e-14	81.0	COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 70	-	-	3.1.11.2,3.2.1.1	ko:K01142,ko:K01176	ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000,ko03400	-	GH13	-	Alpha-amylase,CBM_25,DUF1939,He_PIG
LZS3_k127_3020698_49	880073.Calab_0921	1.08e-18	102.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_3020698_20	247490.KSU1_C0449	9.615e-103	364.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_3020698_48	459349.CLOAM0984	6.431e-19	104.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
LZS3_k127_3020698_32	926562.Oweho_1851	1.117e-50	209.0	COG3420@1|root,COG3420@2|Bacteria,4PPAE@976|Bacteroidetes,1IKH4@117743|Flavobacteriia,2PBVP@246874|Cryomorphaceae	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
LZS3_k127_3020698_29	929556.Solca_0637	4.562e-65	238.0	COG4775@1|root,COG4775@2|Bacteria,4NHNW@976|Bacteroidetes,1IQZB@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
LZS3_k127_3020698_7	1121920.AUAU01000006_gene304	4.066e-176	570.0	COG0405@1|root,COG0405@2|Bacteria,3Y2N0@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
LZS3_k127_3020698_42	862517.HMPREF9225_0643	3.333e-29	126.0	COG2968@1|root,COG2968@2|Bacteria,1UFP4@1239|Firmicutes,24I3T@186801|Clostridia,22III@1570339|Peptoniphilaceae	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
LZS3_k127_3020698_5	1122134.KB893650_gene584	6.978e-198	636.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1XP2X@135619|Oceanospirillales	135619|Oceanospirillales	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
LZS3_k127_3020698_34	880072.Desac_1069	2.452e-37	143.0	COG2337@1|root,COG2337@2|Bacteria,1N0JV@1224|Proteobacteria,42STH@68525|delta/epsilon subdivisions,2WP6X@28221|Deltaproteobacteria,2MSFP@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
LZS3_k127_3020698_45	880072.Desac_1068	3.454e-22	98.0	COG2336@1|root,COG2336@2|Bacteria,1N7YN@1224|Proteobacteria,42VFV@68525|delta/epsilon subdivisions,2WRSX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	SpoVT / AbrB like domain	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
LZS3_k127_3020698_30	517417.Cpar_1374	9.318e-60	218.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,ATP-grasp_4,ATPgrasp_TupA
LZS3_k127_3020698_23	448385.sce1024	6.472e-85	302.0	COG2863@1|root,COG2863@2|Bacteria,1NDS5@1224|Proteobacteria,43CTZ@68525|delta/epsilon subdivisions,2X81J@28221|Deltaproteobacteria,2YVKA@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3020698_58	459349.CLOAM0984	5.031e-11	76.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
LZS3_k127_3020698_40	59374.Fisuc_2892	1.847e-32	141.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
LZS3_k127_3020698_59	1089550.ATTH01000001_gene2515	3.067e-09	70.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,4PM65@976|Bacteroidetes,1FKEM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
LZS3_k127_3020698_65	1216932.CM240_1167	0.000276	53.0	COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,24EU8@186801|Clostridia,36EYC@31979|Clostridiaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS3_k127_3020698_35	1353529.M899_1778	1.455e-36	146.0	COG3148@1|root,COG3148@2|Bacteria,1QJR0@1224|Proteobacteria,42UN7@68525|delta/epsilon subdivisions,2MUDY@213481|Bdellovibrionales,2WQDN@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	DTW	-	-	-	-	-	-	-	-	-	-	-	-	DTW
LZS3_k127_3020698_24	1232410.KI421421_gene3263	3.213e-84	295.0	COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,42NXK@68525|delta/epsilon subdivisions,2WMGN@28221|Deltaproteobacteria,43TBF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,ScdA_N
LZS3_k127_3020698_43	1121920.AUAU01000017_gene1199	2.769e-27	119.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
LZS3_k127_3020698_51	1121930.AQXG01000001_gene1216	1.195e-16	95.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Beta_helix,F5_F8_type_C
LZS3_k127_3020698_22	247490.KSU1_C0449	1.009e-89	325.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_3020698_50	1173021.ALWA01000019_gene386	3.785e-18	96.0	COG3420@1|root,COG3420@2|Bacteria,1G2FG@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1565,SLH
LZS3_k127_3020698_1	1379270.AUXF01000001_gene2703	0.0	1029.0	COG3696@1|root,COG3696@2|Bacteria,1ZUQD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS3_k127_3020698_33	1379270.AUXF01000001_gene2702	5.438e-48	191.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
LZS3_k127_3075494_17	680198.SCAB_77391	2.772e-05	56.0	COG1310@1|root,COG1413@1|root,COG1310@2|Bacteria,COG1413@2|Bacteria,2H3D5@201174|Actinobacteria	201174|Actinobacteria	C	metal-dependent protease of the Pad1 Jab1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3075494_18	794903.OPIT5_03645	0.0005807	50.0	COG5434@1|root,COG5434@2|Bacteria,46U2F@74201|Verrucomicrobia,3K9E5@414999|Opitutae	414999|Opitutae	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3075494_16	880073.Calab_2214	7.376e-18	98.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	-
LZS3_k127_3075494_14	935836.JAEL01000084_gene766	2.128e-40	169.0	COG2273@1|root,COG2273@2|Bacteria,1UA30@1239|Firmicutes,4IKCF@91061|Bacilli,1ZGF5@1386|Bacillus	91061|Bacilli	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
LZS3_k127_3075494_9	483219.LILAB_13740	1.939e-98	333.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2YU0S@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS3_k127_3075494_3	926550.CLDAP_00330	1.982e-194	615.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
LZS3_k127_3075494_0	1379270.AUXF01000003_gene3409	0.0	1232.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,F5_F8_type_C,Glyco_hydro_2_C,Glyco_hydro_53
LZS3_k127_3075494_7	215803.DB30_3122	3.531e-112	372.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2X35I@28221|Deltaproteobacteria,2YUD1@29|Myxococcales	28221|Deltaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
LZS3_k127_3075494_8	448385.sce4300	1.129e-111	376.0	COG1173@1|root,COG1173@2|Bacteria,1R4JX@1224|Proteobacteria,42THM@68525|delta/epsilon subdivisions,2X5XI@28221|Deltaproteobacteria,2YU8B@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter permease	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS3_k127_3075494_4	1144275.COCOR_03970	1.502e-143	465.0	COG0601@1|root,COG0601@2|Bacteria,1NH5E@1224|Proteobacteria,42SMT@68525|delta/epsilon subdivisions,2WPBM@28221|Deltaproteobacteria,2YTSY@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter permease	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS3_k127_3075494_2	1242864.D187_010459	3.666e-217	690.0	COG0747@1|root,COG0747@2|Bacteria,1N4PK@1224|Proteobacteria,42P0B@68525|delta/epsilon subdivisions,2X5XH@28221|Deltaproteobacteria,2YUKB@29|Myxococcales	28221|Deltaproteobacteria	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS3_k127_3075494_11	246197.MXAN_6550	1.325e-91	314.0	COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,43AJK@68525|delta/epsilon subdivisions,2X5ZT@28221|Deltaproteobacteria,2YUVB@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
LZS3_k127_3075494_6	1379270.AUXF01000003_gene3415	6.342e-115	386.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	CBM_6,DUF4971,F5_F8_type_C,Glyco_hydro_16,HemolysinCabind,PA14,Trypsin
LZS3_k127_3075494_1	665571.STHERM_c13850	5.065e-299	953.0	28HKI@1|root,2Z7VC@2|Bacteria,2J736@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3075494_5	1379698.RBG1_1C00001G1092	1.623e-126	433.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.4.17.18,3.4.17.22	ko:K05996,ko:K07752	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	F5_F8_type_C,Peptidase_M14,Peptidase_M6,Ricin_B_lectin,fn3
LZS3_k127_3075494_13	1121918.ARWE01000001_gene1421	1.057e-74	270.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,43S65@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS3_k127_3075494_15	1502852.FG94_00654	1.339e-25	123.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
LZS3_k127_3075494_10	1007103.AFHW01000004_gene4428	8.148e-95	320.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,4HB6P@91061|Bacilli,26UJA@186822|Paenibacillaceae	91061|Bacilli	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
LZS3_k127_3075494_12	1121104.AQXH01000006_gene2318	3.092e-80	276.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1IWBX@117747|Sphingobacteriia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
LZS3_k127_310709_6	1191523.MROS_0963	3.924e-12	79.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_310709_5	1232410.KI421418_gene2415	5.016e-13	81.0	COG1269@1|root,COG1269@2|Bacteria,1RF6T@1224|Proteobacteria,42RJJ@68525|delta/epsilon subdivisions,2WNWF@28221|Deltaproteobacteria,43UKN@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
LZS3_k127_310709_2	883.DvMF_0672	4.43e-51	193.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria,2MAPG@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM eight transmembrane protein EpsH	epsH	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
LZS3_k127_310709_8	1121272.KB903293_gene7319	1.29e-06	61.0	COG3325@1|root,COG3469@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3469@2|Bacteria,COG3979@2|Bacteria,2GJGW@201174|Actinobacteria,4DBUK@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	chiC	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_2,Glyco_hydro_18
LZS3_k127_310709_0	1234364.AMSF01000010_gene552	8.562e-99	335.0	2DBFX@1|root,2Z917@2|Bacteria,1P4PR@1224|Proteobacteria,1RWCW@1236|Gammaproteobacteria,1X36T@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_310709_4	1234364.AMSF01000010_gene545	3.016e-39	164.0	COG3307@1|root,COG3307@2|Bacteria,1N4HJ@1224|Proteobacteria,1SWM6@1236|Gammaproteobacteria,1X57W@135614|Xanthomonadales	135614|Xanthomonadales	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
LZS3_k127_310709_3	1120968.AUBX01000018_gene2090	5.417e-48	190.0	COG0438@1|root,COG0438@2|Bacteria,4NE6S@976|Bacteroidetes,47P7K@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
LZS3_k127_310709_1	525897.Dbac_2204	2.464e-73	264.0	COG0726@1|root,COG0726@2|Bacteria,1MZFC@1224|Proteobacteria,42M7D@68525|delta/epsilon subdivisions,2WKVW@28221|Deltaproteobacteria,2M97N@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS3_k127_310709_9	314278.NB231_08192	7.61e-06	57.0	COG2334@1|root,COG2334@2|Bacteria,1QT51@1224|Proteobacteria,1STMM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
LZS3_k127_310709_7	575590.HMPREF0156_00890	1.452e-08	68.0	COG5652@1|root,COG5652@2|Bacteria,4NIE7@976|Bacteroidetes	976|Bacteroidetes	S	Heparinase II/III-like protein	-	GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510	4.2.2.7,4.2.2.8	ko:K19051	-	-	-	-	ko00000,ko01000	-	PL21	-	DUF4962,Hepar_II_III
LZS3_k127_3151819_4	459349.CLOAM1781	1.631e-06	61.0	COG2931@1|root,COG3291@1|root,COG2931@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K07282,ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11	-	-	HemolysinCabind,VCBS
LZS3_k127_3151819_2	1192034.CAP_2122	6.832e-75	278.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_3151819_3	945713.IALB_2396	3.541e-14	87.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
LZS3_k127_3151819_1	1192034.CAP_3762	6.499e-85	309.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2YZYM@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_3151819_0	331678.Cphamn1_1670	1.439e-106	353.0	COG1397@1|root,COG1397@2|Bacteria	2|Bacteria	O	ADP-ribosylglycohydrolase	draG	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,Inositol_P
LZS3_k127_3226496_8	1210884.HG799464_gene10587	3.926e-05	48.0	COG0714@1|root,COG0714@2|Bacteria,2IWZM@203682|Planctomycetes	203682|Planctomycetes	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS3_k127_3226496_6	908612.HMPREF9720_1225	4.868e-20	104.0	COG2304@1|root,COG2304@2|Bacteria,4NFNQ@976|Bacteroidetes,2FMMK@200643|Bacteroidia,22UP3@171550|Rikenellaceae	976|Bacteroidetes	S	Peptidase M64 N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
LZS3_k127_3226496_1	1379698.RBG1_1C00001G1616	1.242e-80	299.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
LZS3_k127_3226496_4	351607.Acel_1033	1.493e-28	120.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	hom	-	1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19	ko:K00003,ko:K00058,ko:K01754,ko:K04767	ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00017,M00018,M00020,M00570	R00220,R00996,R01513,R01773,R01775	RC00031,RC00087,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3
LZS3_k127_3226496_3	502025.Hoch_2129	6.397e-74	263.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2X1W0@28221|Deltaproteobacteria,2YUZR@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_3226496_0	1123377.AUIV01000037_gene2138	9.852e-92	311.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1S032@1236|Gammaproteobacteria,1X3H4@135614|Xanthomonadales	135614|Xanthomonadales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
LZS3_k127_3226496_5	1449049.JONW01000006_gene3277	1.689e-27	115.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2UDEK@28211|Alphaproteobacteria,2KGZA@204458|Caulobacterales	204458|Caulobacterales	S	PFAM Membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
LZS3_k127_3226496_2	380358.XALC_1219	1.504e-74	259.0	COG0500@1|root,COG0500@2|Bacteria,1QWHM@1224|Proteobacteria,1T47V@1236|Gammaproteobacteria,1XCTD@135614|Xanthomonadales	135614|Xanthomonadales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_3254193_2	204669.Acid345_4391	9.53e-24	101.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
LZS3_k127_3254193_0	204669.Acid345_4118	2.205e-247	803.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
LZS3_k127_3254193_1	234267.Acid_4431	2.628e-167	559.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
LZS3_k127_3302030_1	204669.Acid345_4118	8.701e-143	473.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
LZS3_k127_3302030_0	234267.Acid_5940	6.706e-188	617.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_3357360_19	398767.Glov_3567	3.427e-46	171.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,43TPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
LZS3_k127_3357360_4	243231.GSU3102	1.147e-129	443.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,43TD6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
LZS3_k127_3357360_13	292459.STH74	1.953e-59	218.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
LZS3_k127_3357360_5	1499967.BAYZ01000115_gene2927	8.02e-129	422.0	COG0216@1|root,COG0216@2|Bacteria,2NNKY@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS3_k127_3357360_10	1123288.SOV_3c04300	6.869e-77	270.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,4H271@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
LZS3_k127_3357360_24	349741.Amuc_1430	1.901e-24	106.0	COG0254@1|root,COG0254@2|Bacteria,46T4W@74201|Verrucomicrobia,2IUJ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L31	-	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
LZS3_k127_3357360_22	1380347.JNII01000008_gene4181	6.183e-28	122.0	COG1266@1|root,COG1266@2|Bacteria,2IS6T@201174|Actinobacteria	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
LZS3_k127_3357360_2	671143.DAMO_2285	2.298e-192	607.0	COG3303@1|root,COG3303@2|Bacteria,2NQQ2@2323|unclassified Bacteria	2|Bacteria	P	Seven times multi-haem cytochrome CxxCH	hao	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114	1.7.2.6	ko:K10535	ko00910,ko01120,map00910,map01120	M00528,M00804	R10164	RC00383	ko00000,ko00001,ko00002,ko01000	-	-	-	Multi-haem_cyto
LZS3_k127_3357360_27	1234664.AMRO01000027_gene1215	7.174e-17	89.0	2AFVE@1|root,315XY@2|Bacteria,1V9WC@1239|Firmicutes,4HJ2Y@91061|Bacilli,1WHEF@129337|Geobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3357360_0	1379698.RBG1_1C00001G0312	2.661e-203	639.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
LZS3_k127_3357360_29	246197.MXAN_1324	9.705e-08	64.0	COG0457@1|root,COG4235@1|root,COG0457@2|Bacteria,COG4235@2|Bacteria,1PEH7@1224|Proteobacteria,42TVC@68525|delta/epsilon subdivisions,2WSCX@28221|Deltaproteobacteria,2YXM3@29|Myxococcales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TPR_14,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8
LZS3_k127_3357360_3	1340434.AXVA01000003_gene1774	2.632e-153	514.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
LZS3_k127_3357360_28	56110.Oscil6304_4090	1.03e-09	68.0	COG4194@1|root,COG4194@2|Bacteria	2|Bacteria	K	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
LZS3_k127_3357360_1	247490.KSU1_C1713	1.47e-197	642.0	COG2303@1|root,COG2303@2|Bacteria,2J0GF@203682|Planctomycetes	203682|Planctomycetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
LZS3_k127_3357360_21	926561.KB900617_gene1496	1.377e-37	144.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,3WAJ5@53433|Halanaerobiales	186801|Clostridia	K	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_3357360_20	289376.THEYE_A2006	8.218e-41	175.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,3J18S@40117|Nitrospirae	40117|Nitrospirae	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3357360_18	1089553.Tph_c04850	3.1e-46	193.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42F3M@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS3_k127_3357360_17	309799.DICTH_1958	3.054e-48	199.0	COG0834@1|root,COG2203@1|root,COG3437@1|root,COG0834@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K02030,ko:K13040	ko02020,map02020	M00236,M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.3	-	-	EAL,GAF_2,GGDEF,HATPase_c,HD,HD_5,HisKA,PAS_3,PAS_9,Response_reg,SBP_bac_3
LZS3_k127_3357360_15	635013.TherJR_2128	1.723e-52	213.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
LZS3_k127_3357360_26	459495.SPLC1_S082360	1.614e-22	110.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG2905@1|root,COG2964@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2905@2|Bacteria,COG2964@2|Bacteria,1G09B@1117|Cyanobacteria,1H71H@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
LZS3_k127_3357360_11	720554.Clocl_0522	7.812e-76	265.0	COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,3WGN1@541000|Ruminococcaceae	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
LZS3_k127_3357360_8	187272.Mlg_2520	1.529e-88	302.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1WWRX@135613|Chromatiales	135613|Chromatiales	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
LZS3_k127_3357360_16	1051985.l11_08130	2.737e-48	175.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KR9Y@206351|Neisseriales	206351|Neisseriales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
LZS3_k127_3357360_25	215803.DB30_4432	1.437e-22	103.0	COG0764@1|root,COG0764@2|Bacteria	2|Bacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	fabZ	-	3.5.1.108,4.2.1.59	ko:K02372,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212	M00060,M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
LZS3_k127_3357360_7	595460.RRSWK_06093	3.741e-96	330.0	COG0304@1|root,COG0304@2|Bacteria,2IX8X@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_3357360_30	1142394.PSMK_24110	6.696e-06	52.0	COG0236@1|root,COG0236@2|Bacteria,2J04I@203682|Planctomycetes	203682|Planctomycetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS3_k127_3357360_14	562970.Btus_2604	1.229e-54	202.0	COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,27AT7@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	fabL	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_3357360_23	391603.FBALC1_03307	4.478e-27	128.0	29X8I@1|root,30IXV@2|Bacteria,4P0MB@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3357360_12	391625.PPSIR1_04548	2.099e-65	232.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YUT4@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_3357360_9	1160718.SU9_22460	5.265e-85	316.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
LZS3_k127_3357360_6	316067.Geob_2763	3.645e-123	427.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
LZS3_k127_3377128_15	396588.Tgr7_0951	1.427e-11	72.0	COG1716@1|root,COG1716@2|Bacteria,1PFS9@1224|Proteobacteria,1RU6A@1236|Gammaproteobacteria,1X1M2@135613|Chromatiales	135613|Chromatiales	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
LZS3_k127_3377128_11	1501391.LG35_05925	1.207e-26	122.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22V8H@171550|Rikenellaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
LZS3_k127_3377128_4	1379698.RBG1_1C00001G1773	2.629e-88	314.0	COG0457@1|root,COG0457@2|Bacteria,2NP5J@2323|unclassified Bacteria	2|Bacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
LZS3_k127_3377128_5	1379698.RBG1_1C00001G1774	7.186e-83	298.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
LZS3_k127_3377128_3	1519464.HY22_00735	4.423e-92	313.0	COG2304@1|root,COG2304@2|Bacteria,1FDYE@1090|Chlorobi	1090|Chlorobi	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
LZS3_k127_3377128_14	1499967.BAYZ01000069_gene1844	6.883e-15	88.0	2DQMB@1|root,337KD@2|Bacteria,2NQ86@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3377128_2	1379698.RBG1_1C00001G1778	4.657e-98	331.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
LZS3_k127_3377128_0	1242864.D187_006463	9.416e-137	446.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
LZS3_k127_3377128_7	1123371.ATXH01000045_gene1871	1.293e-57	211.0	28I4Y@1|root,2Z88D@2|Bacteria,2GI90@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3377128_9	1131269.AQVV01000016_gene1838	1.099e-44	171.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	pgp	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS3_k127_3377128_1	262724.TT_P0211	9.878e-119	394.0	COG1373@1|root,COG1373@2|Bacteria,1WJIW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
LZS3_k127_3377128_13	1469607.KK073769_gene6107	5.1e-15	78.0	COG0864@1|root,COG0864@2|Bacteria,1G9E4@1117|Cyanobacteria,1HPW8@1161|Nostocales	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3377128_10	317936.Nos7107_1390	7.831e-36	143.0	COG2337@1|root,COG2337@2|Bacteria,1G5S4@1117|Cyanobacteria,1HU8C@1161|Nostocales	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
LZS3_k127_3377128_12	383372.Rcas_4129	4.391e-25	111.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
LZS3_k127_3377128_6	290397.Adeh_3883	2.312e-73	269.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2Z1PP@29|Myxococcales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM,TPR_14,TPR_16
LZS3_k127_3377128_8	644966.Tmar_0285	1.683e-53	216.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WCQQ@538999|Clostridiales incertae sedis	186801|Clostridia	L	UvrD/REP helicase N-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS3_k127_3377128_16	907239.HPSA_01810	1.093e-07	64.0	COG2887@1|root,COG2887@2|Bacteria,1QUIU@1224|Proteobacteria,42M7I@68525|delta/epsilon subdivisions,2YMX0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	COG3893 inactivated superfamily I helicase	addB	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
LZS3_k127_3555385_13	314345.SPV1_09643	2.186e-67	233.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
LZS3_k127_3555385_7	316067.Geob_0097	9.515e-122	400.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria,43TA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	bamQ	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_3555385_3	1187851.A33M_3194	1.591e-152	489.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_3555385_12	404380.Gbem_1432	3.258e-72	252.0	COG1024@1|root,COG1024@2|Bacteria,1R7WW@1224|Proteobacteria,42NZQ@68525|delta/epsilon subdivisions,2WMCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
LZS3_k127_3555385_6	85643.Tmz1t_2951	2.526e-131	439.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
LZS3_k127_3555385_0	1244869.H261_12286	2.414e-184	606.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
LZS3_k127_3555385_4	652103.Rpdx1_4127	3.476e-145	487.0	COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
LZS3_k127_3555385_10	258594.RPA0660	3.031e-93	316.0	COG1924@1|root,COG1924@2|Bacteria,1MY0N@1224|Proteobacteria,2U4V9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
LZS3_k127_3555385_16	648757.Rvan_0041	2.206e-50	199.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2U2FQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_3555385_20	1232410.KI421421_gene3250	6.679e-35	141.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_3555385_24	1118153.MOY_13935	4.39e-12	76.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1XJI3@135619|Oceanospirillales	135619|Oceanospirillales	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
LZS3_k127_3555385_14	518766.Rmar_2387	1.772e-63	231.0	COG3203@1|root,COG3203@2|Bacteria,4NPPT@976|Bacteroidetes	976|Bacteroidetes	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3555385_15	880073.Calab_0852	1.943e-63	230.0	COG3203@1|root,COG3203@2|Bacteria,2NQU9@2323|unclassified Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
LZS3_k127_3555385_1	518766.Rmar_0497	1.943e-183	593.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1FKD5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
LZS3_k127_3555385_11	880073.Calab_1288	4.255e-74	264.0	COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
LZS3_k127_3555385_21	926560.KE387023_gene2608	1.039e-25	110.0	COG3478@1|root,COG3478@2|Bacteria	2|Bacteria	S	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)	ypzJ	-	-	ko:K07069	-	-	-	-	ko00000	-	-	-	zinc_ribbon_13
LZS3_k127_3555385_8	1191523.MROS_2643	7.465e-121	407.0	COG1520@1|root,COG5492@1|root,COG1520@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,TIG
LZS3_k127_3555385_2	1191523.MROS_2644	2.739e-157	531.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug,TonB_dep_Rec
LZS3_k127_3555385_17	933262.AXAM01000091_gene2605	2.119e-41	163.0	COG2433@1|root,COG2433@2|Bacteria,1QWQ9@1224|Proteobacteria,42WRY@68525|delta/epsilon subdivisions,2WQU6@28221|Deltaproteobacteria,2MPKU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
LZS3_k127_3555385_9	1121396.KB893105_gene1800	4.754e-117	400.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,42NWR@68525|delta/epsilon subdivisions,2WK2E@28221|Deltaproteobacteria,2MN43@213118|Desulfobacterales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	DUF3450,MotA_ExbB
LZS3_k127_3555385_19	1265505.ATUG01000002_gene2253	1.626e-39	154.0	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,42S37@68525|delta/epsilon subdivisions,2WNDZ@28221|Deltaproteobacteria,2MJWJ@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS3_k127_3555385_18	644282.Deba_2294	2.131e-40	160.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,42SKN@68525|delta/epsilon subdivisions,2WP1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS3_k127_3555385_23	522772.Dacet_1608	4.973e-18	93.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
LZS3_k127_3555385_22	1232437.KL662011_gene1452	8.531e-24	116.0	COG0457@1|root,COG0457@2|Bacteria,1QSIA@1224|Proteobacteria,42PM6@68525|delta/epsilon subdivisions,2WKPH@28221|Deltaproteobacteria,2MIQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
LZS3_k127_3555385_5	118005.AWNK01000011_gene148	2.917e-143	461.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS3_k127_3638962_4	96561.Dole_0405	9.714e-52	192.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42QJY@68525|delta/epsilon subdivisions,2WK0U@28221|Deltaproteobacteria,2MK7F@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
LZS3_k127_3638962_3	1043205.AFYF01000072_gene2224	3.907e-68	246.0	COG1131@1|root,COG1131@2|Bacteria,2IBJD@201174|Actinobacteria,4FIR1@85021|Intrasporangiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS3_k127_3638962_0	266779.Meso_2241	6.827e-153	495.0	COG2235@1|root,COG2235@2|Bacteria,1NCGV@1224|Proteobacteria,2TU0Z@28211|Alphaproteobacteria,43GUQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Arginine	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
LZS3_k127_3638962_1	1216966.BAUC01000022_gene1664	1.274e-149	490.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argI	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0033554,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0273,iECDH10B_1368.ECDH10B_0261,iECS88_1305.ECS88_4841,iJO1366.b0273,iJR904.b0273,iY75_1357.Y75_RS01410	OTCace,OTCace_N
LZS3_k127_3638962_2	1122207.MUS1_07760	5.607e-118	386.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria,1XIJN@135619|Oceanospirillales	135619|Oceanospirillales	E	Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS3_k127_3638962_5	502025.Hoch_3377	3.277e-09	68.0	COG0842@1|root,COG0842@2|Bacteria,1NRMT@1224|Proteobacteria,43B3S@68525|delta/epsilon subdivisions,2X6HQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS3_k127_3684957_2	880073.Calab_2916	6.891e-73	273.0	COG2838@1|root,COG2838@2|Bacteria	2|Bacteria	C	Isocitrate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
LZS3_k127_3684957_0	713587.THITH_13970	0.0	1257.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1WWC8@135613|Chromatiales	135613|Chromatiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
LZS3_k127_3684957_1	555079.Toce_0820	3.355e-188	617.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,248CT@186801|Clostridia,42ERR@68295|Thermoanaerobacterales	186801|Clostridia	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
LZS3_k127_3706127_30	546271.Selsp_1820	2.424e-59	229.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4H294@909932|Negativicutes	909932|Negativicutes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
LZS3_k127_3706127_28	1121918.ARWE01000001_gene872	2.015e-66	243.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,43TAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
LZS3_k127_3706127_15	671143.DAMO_2299	2.99e-98	336.0	COG0771@1|root,COG0771@2|Bacteria,2NP27@2323|unclassified Bacteria	2|Bacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAPECO1_1312.APECO1_1898,iECNA114_1301.ECNA114_0081,iECOK1_1307.ECOK1_0089,iECP_1309.ECP_0090,iECS88_1305.ECS88_0091,iECSF_1327.ECSF_0098,iLF82_1304.LF82_1418,iNRG857_1313.NRG857_00450,iUMN146_1321.UM146_23225,iUTI89_1310.UTI89_C0097	Mur_ligase_C,Mur_ligase_M
LZS3_k127_3706127_2	1379698.RBG1_1C00001G0393	2.521e-146	472.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
LZS3_k127_3706127_26	1123322.KB904669_gene3598	4.651e-71	260.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS3_k127_3706127_12	498761.HM1_2054	1.411e-99	343.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
LZS3_k127_3706127_13	316067.Geob_0774	5.731e-99	349.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
LZS3_k127_3706127_23	338963.Pcar_2210	1.84e-76	267.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,43SBK@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	MraW methylase family	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
LZS3_k127_3706127_52	1123372.AUIT01000003_gene899	1.218e-14	79.0	COG2001@1|root,COG2001@2|Bacteria,2GGT9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
LZS3_k127_3706127_55	1108045.GORHZ_080_00130	1.109e-11	75.0	COG0500@1|root,COG2226@2|Bacteria,2HF3W@201174|Actinobacteria,4GFH1@85026|Gordoniaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_3706127_50	682795.AciX8_3927	1.398e-16	93.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_3706127_29	644966.Tmar_0646	2.04e-59	232.0	COG0438@1|root,COG0438@2|Bacteria,1V0G0@1239|Firmicutes,25BFP@186801|Clostridia	186801|Clostridia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_3706127_51	68199.JNZO01000031_gene2971	8.9e-15	85.0	COG5653@1|root,COG5653@2|Bacteria,2IKIG@201174|Actinobacteria	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
LZS3_k127_3706127_6	768706.Desor_5325	6.863e-111	376.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,261AB@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	spsC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_3706127_4	768710.DesyoDRAFT_5080	2.226e-126	427.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,26076@186807|Peptococcaceae	186801|Clostridia	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_syn_2C,Polysacc_synt_2
LZS3_k127_3706127_56	1408813.AYMG01000008_gene4070	6.705e-07	63.0	COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,1IRID@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y
LZS3_k127_3706127_5	1499967.BAYZ01000063_gene6022	5.185e-121	414.0	COG1216@1|root,COG2148@1|root,COG1216@2|Bacteria,COG2148@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K03606,ko:K07011	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3,Glyco_tranf_2_3,Glycos_transf_2
LZS3_k127_3706127_20	379066.GAU_1612	2.329e-83	312.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS3_k127_3706127_11	290317.Cpha266_2437	8.397e-100	357.0	COG5617@1|root,COG5617@2|Bacteria,1FDV6@1090|Chlorobi	1090|Chlorobi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
LZS3_k127_3706127_19	419665.Maeo_0395	3.019e-85	301.0	COG0438@1|root,arCOG01415@2157|Archaea,2XUVW@28890|Euryarchaeota,23R82@183939|Methanococci	183939|Methanococci	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_3706127_16	880073.Calab_1845	1.701e-94	324.0	COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
LZS3_k127_3706127_8	1499967.BAYZ01000176_gene5652	3.654e-104	347.0	COG0451@1|root,COG0451@2|Bacteria,2NNT0@2323|unclassified Bacteria	2|Bacteria	M	Polysaccharide biosynthesis protein	ytcB	-	5.1.3.2,5.1.3.6	ko:K01784,ko:K08679	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01385,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS3_k127_3706127_7	1379698.RBG1_1C00001G0356	3.069e-109	384.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
LZS3_k127_3706127_43	59374.Fisuc_0693	1.139e-30	136.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS3_k127_3706127_14	1379698.RBG1_1C00001G1319	2.657e-98	340.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_3706127_31	59374.Fisuc_0695	5.797e-56	205.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
LZS3_k127_3706127_32	880073.Calab_0215	1.265e-55	209.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
LZS3_k127_3706127_45	518766.Rmar_0030	2.322e-23	106.0	COG0781@1|root,COG0781@2|Bacteria,4NDVR@976|Bacteroidetes,1FJJ7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
LZS3_k127_3706127_39	235909.GK2294	2.653e-37	148.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,1WEXX@129337|Geobacillus	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
LZS3_k127_3706127_0	1089553.Tph_c14030	4.129e-161	517.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,42FC2@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
LZS3_k127_3706127_35	457425.XNR_5406	6.401e-45	169.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria	201174|Actinobacteria	H	riboflavin synthase, alpha	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
LZS3_k127_3706127_25	1123072.AUDH01000028_gene1872	1.187e-71	258.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,2JPG9@204441|Rhodospirillales	204441|Rhodospirillales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
LZS3_k127_3706127_59	246200.SPO0268	0.0002039	47.0	COG0054@1|root,COG0054@2|Bacteria,1RHCZ@1224|Proteobacteria,2U5EC@28211|Alphaproteobacteria,4NBYE@97050|Ruegeria	28211|Alphaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH2	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
LZS3_k127_3706127_21	555079.Toce_1063	1.427e-81	281.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,42ENW@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
LZS3_k127_3706127_1	518766.Rmar_0643	2.15e-148	513.0	COG1196@1|root,COG1196@2|Bacteria,4NHWQ@976|Bacteroidetes,1FIP5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
LZS3_k127_3706127_18	1121468.AUBR01000016_gene2303	1.156e-85	301.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,42F61@68295|Thermoanaerobacterales	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1,4.3.1.29	ko:K01042,ko:K17468	ko00030,ko00450,ko00970,ko01120,map00030,map00450,map00970,map01120	-	R08219,R10408	RC00544,RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
LZS3_k127_3706127_46	879310.HMPREF9162_1376	8.574e-21	108.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,4H8VU@909932|Negativicutes	909932|Negativicutes	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
LZS3_k127_3706127_57	1445613.JALM01000024_gene4449	4.866e-05	57.0	COG0860@1|root,COG3409@1|root,COG0860@2|Bacteria,COG3409@2|Bacteria,2GPA9@201174|Actinobacteria,4E10H@85010|Pseudonocardiales	201174|Actinobacteria	M	N-acetylmuramoyl-L-alanine amidase	cwlM	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1
LZS3_k127_3706127_54	448385.sce7062	2.42e-12	76.0	COG0810@1|root,COG4206@1|root,COG0810@2|Bacteria,COG4206@2|Bacteria,1N71E@1224|Proteobacteria	1224|Proteobacteria	H	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
LZS3_k127_3706127_49	215803.DB30_6990	1.254e-19	104.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2YYTD@29|Myxococcales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
LZS3_k127_3706127_41	1379698.RBG1_1C00001G0129	1.745e-34	140.0	COG1259@1|root,COG1259@2|Bacteria,2NP7X@2323|unclassified Bacteria	2|Bacteria	S	Bifunctional nuclease	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03617,ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase,UVR
LZS3_k127_3706127_58	1122179.KB890420_gene2490	9.741e-05	54.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
LZS3_k127_3706127_53	1218084.BBJK01000076_gene5293	2.404e-12	79.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1K2ZM@119060|Burkholderiaceae	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS3_k127_3706127_17	1121468.AUBR01000001_gene508	3.238e-88	303.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,42FA6@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Nucleotidyl transferase	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
LZS3_k127_3706127_42	1382359.JIAL01000001_gene1373	1.87e-32	131.0	COG0359@1|root,COG0359@2|Bacteria,3Y4MD@57723|Acidobacteria,2JJAN@204432|Acidobacteriia	204432|Acidobacteriia	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
LZS3_k127_3706127_47	1499967.BAYZ01000179_gene4639	9.981e-21	95.0	COG0238@1|root,COG0238@2|Bacteria,2NPTU@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
LZS3_k127_3706127_48	1262449.CP6013_3150	1.163e-19	94.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,36JK5@31979|Clostridiaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
LZS3_k127_3706127_36	575540.Isop_2892	3.764e-44	168.0	COG0193@1|root,COG0193@2|Bacteria,2IZXT@203682|Planctomycetes	203682|Planctomycetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
LZS3_k127_3706127_38	1379698.RBG1_1C00001G0172	7.375e-38	150.0	COG1825@1|root,COG1825@2|Bacteria,2NPVU@2323|unclassified Bacteria	2|Bacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
LZS3_k127_3706127_10	1379698.RBG1_1C00001G0643	2e-101	339.0	COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
LZS3_k127_3706127_44	404589.Anae109_0126	8.047e-26	109.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2WQYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
LZS3_k127_3706127_33	1173263.Syn7502_02413	2.639e-51	193.0	COG1947@1|root,COG1947@2|Bacteria,1G0YY@1117|Cyanobacteria,1GZVI@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
LZS3_k127_3706127_24	1499967.BAYZ01000193_gene3921	1.857e-75	264.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
LZS3_k127_3706127_27	400682.PAC_15706214	2.496e-67	259.0	2CZW5@1|root,2SBX5@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
LZS3_k127_3706127_34	323261.Noc_2167	4.876e-49	187.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,1WX5U@135613|Chromatiales	135613|Chromatiales	M	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_3706127_9	1150626.PHAMO_210039	9.587e-103	348.0	COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2TU8I@28211|Alphaproteobacteria,2JQNW@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
LZS3_k127_3706127_37	269796.Rru_A2605	1.309e-43	177.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,2U8QT@28211|Alphaproteobacteria,2JSGE@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
LZS3_k127_3706127_3	671143.DAMO_2778	3.296e-132	435.0	COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria	2|Bacteria	M	Nucleotidyl transferase	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS3_k127_3706127_40	515635.Dtur_0599	6.17e-37	158.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
LZS3_k127_3706127_22	309801.trd_0726	7.122e-78	271.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi,27XHJ@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS3_k127_3784881_54	880073.Calab_0921	4.816e-16	93.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_3784881_21	448385.sce1024	1.004e-54	218.0	COG2863@1|root,COG2863@2|Bacteria,1NDS5@1224|Proteobacteria,43CTZ@68525|delta/epsilon subdivisions,2X81J@28221|Deltaproteobacteria,2YVKA@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3784881_2	459349.CLOAM0177	9.009e-187	599.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
LZS3_k127_3784881_66	794903.OPIT5_19705	0.0005214	50.0	COG2834@1|root,COG2834@2|Bacteria,46YSI@74201|Verrucomicrobia,3K9A7@414999|Opitutae	414999|Opitutae	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3784881_23	1174528.JH992898_gene2276	1.917e-53	201.0	COG1409@1|root,COG1409@2|Bacteria,1G4KM@1117|Cyanobacteria	1117|Cyanobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
LZS3_k127_3784881_61	1907.SGLAU_09540	1.076e-08	66.0	COG2227@1|root,COG2227@2|Bacteria,2GMAR@201174|Actinobacteria	201174|Actinobacteria	H	methyltransferase	smtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
LZS3_k127_3784881_4	479434.Sthe_1858	1.19e-129	426.0	COG0579@1|root,COG0579@2|Bacteria,2G67E@200795|Chloroflexi,27XHD@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD dependent oxidoreductase	-	-	1.1.99.2	ko:K00109	ko00650,map00650	-	R03534	RC00031	ko00000,ko00001,ko01000	-	-	-	DAO
LZS3_k127_3784881_27	517418.Ctha_2727	1.983e-42	159.0	COG0011@1|root,COG0011@2|Bacteria,1FE3X@1090|Chlorobi	1090|Chlorobi	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
LZS3_k127_3784881_1	246194.CHY_2385	1.707e-204	656.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,42FHK@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM formate-tetrahydrofolate ligase FTHFS	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
LZS3_k127_3784881_37	941449.dsx2_0195	2.996e-32	127.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WRRT@28221|Deltaproteobacteria,2MCID@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_3784881_35	941449.dsx2_0195	2.659e-33	130.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WRRT@28221|Deltaproteobacteria,2MCID@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_3784881_40	1249480.B649_10470	1.787e-29	123.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,42W05@68525|delta/epsilon subdivisions,2YSWM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
LZS3_k127_3784881_25	91464.S7335_701	1.47e-44	169.0	COG0758@1|root,COG0758@2|Bacteria,1GACU@1117|Cyanobacteria	1117|Cyanobacteria	LU	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
LZS3_k127_3784881_29	643648.Slip_1894	1.812e-41	158.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
LZS3_k127_3784881_5	945713.IALB_2433	2.791e-121	406.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	DUF3318,Peptidase_M48
LZS3_k127_3784881_12	945713.IALB_2434	7.237e-72	246.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
LZS3_k127_3784881_46	945713.IALB_2435	2.68e-23	105.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	Rhomboid,zf-TFIIB
LZS3_k127_3784881_0	123214.PERMA_1704	1.035e-245	777.0	COG0021@1|root,COG0021@2|Bacteria,2G42N@200783|Aquificae	200783|Aquificae	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
LZS3_k127_3784881_15	402777.KB235904_gene3532	7.323e-69	242.0	COG1011@1|root,COG1011@2|Bacteria,1G4JI@1117|Cyanobacteria,1H8VT@1150|Oscillatoriales	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
LZS3_k127_3784881_59	880072.Desac_1567	1.124e-09	66.0	290YH@1|root,2ZNK8@2|Bacteria,1P7TZ@1224|Proteobacteria,433I3@68525|delta/epsilon subdivisions,2WXS0@28221|Deltaproteobacteria,2MSEA@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3784881_55	743722.Sph21_2706	1.577e-15	83.0	2APBA@1|root,31EDH@2|Bacteria,4NPIT@976|Bacteroidetes,1ITA2@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
LZS3_k127_3784881_47	1379698.RBG1_1C00001G1215	1.272e-22	110.0	COG0526@1|root,COG0526@2|Bacteria,2NS00@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin	-	-	-	ko:K12057	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	Thioredoxin,Thioredoxin_9
LZS3_k127_3784881_9	502025.Hoch_6778	9.91e-90	316.0	COG0491@1|root,COG0491@2|Bacteria,1Q2NG@1224|Proteobacteria,4389J@68525|delta/epsilon subdivisions,2X3IZ@28221|Deltaproteobacteria,2YWA6@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_3784881_18	370438.PTH_1832	1.016e-61	226.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,261KY@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
LZS3_k127_3784881_22	416348.Hlac_3592	6.478e-54	212.0	COG3119@1|root,arCOG02785@2157|Archaea,2XUB1@28890|Euryarchaeota,23TRP@183963|Halobacteria	183963|Halobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
LZS3_k127_3784881_63	880073.Calab_2081	2.118e-07	64.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_3784881_67	591167.Sfla_1725	0.0006357	53.0	COG4733@1|root,COG4733@2|Bacteria,2HCWC@201174|Actinobacteria	201174|Actinobacteria	Q	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PA14
LZS3_k127_3784881_16	247490.KSU1_C0449	9.149e-67	256.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_3784881_51	234267.Acid_6886	2.475e-18	92.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_3784881_33	497965.Cyan7822_3560	6.122e-35	155.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,3KGI4@43988|Cyanothece	1117|Cyanobacteria	N	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_8
LZS3_k127_3784881_6	84531.JMTZ01000043_gene1180	2.821e-117	391.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RPIE@1236|Gammaproteobacteria,1X3AS@135614|Xanthomonadales	135614|Xanthomonadales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_3784881_31	1194165.CAJF01000005_gene2377	4.009e-36	154.0	COG0619@1|root,COG1122@1|root,COG0619@2|Bacteria,COG1122@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	-	ko:K16784,ko:K16785,ko:K16786,ko:K16787,ko:K16927	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF_trnsprt
LZS3_k127_3784881_14	1396418.BATQ01000117_gene4574	1.081e-69	249.0	COG0042@1|root,COG0042@2|Bacteria,46SIG@74201|Verrucomicrobia,2ITHJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
LZS3_k127_3784881_38	945713.IALB_1464	3.064e-31	142.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	luxD	-	3.2.1.4,4.2.99.18	ko:K01179,ko:K06889,ko:K10773,ko:K15853	ko00500,ko01100,ko02020,ko02024,ko03410,map00500,map01100,map02020,map02024,map03410	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko03400	-	GH5,GH9	-	Abhydrolase_1,Acyl_transf_2,DLH,Hydrolase_4,Peptidase_S9
LZS3_k127_3784881_3	234267.Acid_5749	1.777e-158	533.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
LZS3_k127_3784881_50	459349.CLOAM0631	3.092e-19	104.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
LZS3_k127_3784881_43	523791.Kkor_1008	7.851e-29	136.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1S07F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
LZS3_k127_3784881_10	253839.SSNG_06193	2.835e-86	320.0	COG3210@1|root,COG4409@1|root,COG3210@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Calx-beta,DUF1573,F5_F8_type_C,Haemagg_act
LZS3_k127_3784881_26	555079.Toce_0247	1.867e-42	164.0	COG4359@1|root,COG4359@2|Bacteria,1TSZ9@1239|Firmicutes,24IHI@186801|Clostridia,42GA1@68295|Thermoanaerobacterales	186801|Clostridia	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	mtnX	-	-	-	-	-	-	-	-	-	-	-	HAD,Put_Phosphatase
LZS3_k127_3784881_7	459349.CLOAM0355	1.245e-112	386.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
LZS3_k127_3784881_36	290397.Adeh_1721	6.52e-33	136.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WN3N@28221|Deltaproteobacteria,2YVHP@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS3_k127_3784881_32	1382306.JNIM01000001_gene4120	1.301e-35	143.0	COG0558@1|root,COG0558@2|Bacteria,2G6RT@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS3_k127_3784881_13	313596.RB2501_07415	1.195e-71	250.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1HX5Y@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
LZS3_k127_3784881_8	246197.MXAN_1432	1.138e-106	356.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria,2YUBW@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
LZS3_k127_3784881_41	1379698.RBG1_1C00001G1143	1.946e-29	123.0	COG0776@1|root,COG0776@2|Bacteria,2NPU6@2323|unclassified Bacteria	2|Bacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup_1	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS3_k127_3784881_65	635013.TherJR_1130	6.622e-06	55.0	COG4733@1|root,COG4733@2|Bacteria,1TQ2T@1239|Firmicutes,24EP0@186801|Clostridia,265Y1@186807|Peptococcaceae	186801|Clostridia	C	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,PKD,Paired_CXXCH_1,SLH,fn3
LZS3_k127_3784881_28	1047013.AQSP01000083_gene1194	3.491e-42	173.0	COG1994@1|root,COG1994@2|Bacteria,2NPQP@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	ywhC	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M50
LZS3_k127_3784881_30	195253.Syn6312_0583	2.87e-38	154.0	COG0602@1|root,COG0602@2|Bacteria,1G13F@1117|Cyanobacteria,1GZJC@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
LZS3_k127_3784881_42	1121472.AQWN01000003_gene1484	2.104e-29	127.0	COG2029@1|root,COG2029@2|Bacteria,1V5P0@1239|Firmicutes,24IRW@186801|Clostridia,261U3@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF366)	-	-	-	ko:K09139	-	-	-	-	ko00000	-	-	-	DUF366
LZS3_k127_3784881_24	1121468.AUBR01000032_gene1173	4.352e-52	192.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,42GV6@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
LZS3_k127_3784881_48	1269813.ATUL01000023_gene653	7.711e-22	104.0	COG0720@1|root,COG0720@2|Bacteria,1PNDM@1224|Proteobacteria,1S7ZW@1236|Gammaproteobacteria,1WZ30@135613|Chromatiales	135613|Chromatiales	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
LZS3_k127_3784881_57	5811.TGME49_073500	2.44e-11	76.0	COG3914@1|root,KOG4626@2759|Eukaryota,3YB6K@5794|Apicomplexa,3YN6Y@5796|Coccidia,3YQYD@5809|Sarcocystidae	5794|Apicomplexa	GOT	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_17,TPR_8
LZS3_k127_3784881_49	1123489.AUAN01000002_gene951	3.962e-21	96.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes	1239|Firmicutes	K	Cold shock	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
LZS3_k127_3784881_45	1379698.RBG1_1C00001G0481	1.608e-23	116.0	COG1716@1|root,COG1716@2|Bacteria,2NQ4X@2323|unclassified Bacteria	2|Bacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,DUF4388,FHA,Yop-YscD_cpl
LZS3_k127_3784881_20	880073.Calab_0215	3.204e-55	202.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
LZS3_k127_3784881_17	1379698.RBG1_1C00001G1613	5.06e-65	245.0	COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria	2|Bacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,PEGA,Pkinase
LZS3_k127_3784881_53	459349.CLOAM0583	3.468e-18	101.0	COG1404@1|root,COG1470@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,CarboxypepD_reg,DUF11,FlgD_ig,HYR,PKD,PPC,SLH,VCBS,fn3
LZS3_k127_3784881_58	1459636.NTE_00699	6.836e-11	77.0	COG3391@1|root,arCOG02562@2157|Archaea	2157|Archaea	Q	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,FG-GAP_2
LZS3_k127_3784881_52	584708.Apau_0290	3.014e-18	99.0	COG0348@1|root,COG0348@2|Bacteria,3TABH@508458|Synergistetes	508458|Synergistetes	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
LZS3_k127_3784881_44	1161401.ASJA01000002_gene2552	9.531e-26	124.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,HCBP_related,HemolysinCabind,P_proprotein,Peptidase_S8
LZS3_k127_3784881_11	448385.sce3387	9.625e-82	295.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_3784881_34	1191523.MROS_0141	8.031e-34	145.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	waaC	-	-	ko:K02841,ko:K02843,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_3784881_19	1410665.JNKR01000015_gene1222	2.515e-60	220.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4H1XQ@909932|Negativicutes	909932|Negativicutes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
LZS3_k127_3784881_39	1232410.KI421421_gene3591	5.54e-30	125.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,43SM8@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
LZS3_k127_3784881_62	697281.Mahau_0304	2.488e-08	61.0	COG1579@1|root,COG1579@2|Bacteria,1UDC6@1239|Firmicutes,25I1B@186801|Clostridia,42IU6@68295|Thermoanaerobacterales	186801|Clostridia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
LZS3_k127_3784881_60	10228.TriadP60819	1.568e-09	72.0	COG0457@1|root,COG3914@1|root,KOG1840@2759|Eukaryota,KOG4626@2759|Eukaryota,3A3MA@33154|Opisthokonta,3BSDD@33208|Metazoa	33208|Metazoa	Z	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF294,Death,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
LZS3_k127_3932543_2	1379698.RBG1_1C00001G0798	1.944e-146	496.0	COG0308@1|root,COG1413@1|root,COG0308@2|Bacteria,COG1413@2|Bacteria,2NPGQ@2323|unclassified Bacteria	2|Bacteria	E	aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
LZS3_k127_3932543_8	1444711.CCJF01000004_gene2291	5.22e-09	61.0	2EQQP@1|root,33IAK@2|Bacteria,2JGJU@204428|Chlamydiae	204428|Chlamydiae	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
LZS3_k127_3932543_3	1379698.RBG1_1C00001G0146	4.041e-78	270.0	COG0356@1|root,COG0356@2|Bacteria,2NPRQ@2323|unclassified Bacteria	2|Bacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
LZS3_k127_3932543_6	1379698.RBG1_1C00001G0147	3.065e-23	100.0	COG0636@1|root,COG0636@2|Bacteria,2NQ21@2323|unclassified Bacteria	2|Bacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
LZS3_k127_3932543_7	1444711.CCJF01000004_gene2295	4.1e-23	105.0	COG0711@1|root,COG0711@2|Bacteria,2JGAI@204428|Chlamydiae	204428|Chlamydiae	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
LZS3_k127_3932543_5	1121289.JHVL01000055_gene533	1.778e-26	115.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,36HY0@31979|Clostridiaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
LZS3_k127_3932543_0	1379698.RBG1_1C00001G0150	4.039e-227	715.0	COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
LZS3_k127_3932543_4	1121938.AUDY01000009_gene2128	1.993e-59	216.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli,3NDXS@45667|Halobacillus	91061|Bacilli	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iSB619.SA_RS10970,iYO844.BSU36820	ATP-synt
LZS3_k127_3932543_1	1379698.RBG1_1C00001G0153	4.74e-187	589.0	COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS3_k127_4093297_1	1123242.JH636434_gene4918	1.223e-94	319.0	COG0005@1|root,COG0005@2|Bacteria,2IX9R@203682|Planctomycetes	203682|Planctomycetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
LZS3_k127_4093297_0	555079.Toce_1642	0.0	1068.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,42F4D@68295|Thermoanaerobacterales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
LZS3_k127_4093297_5	1379698.RBG1_1C00001G0104	1.417e-16	84.0	COG1734@1|root,COG1734@2|Bacteria,2NPX2@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulator, TraR DksA family	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
LZS3_k127_4093297_3	439292.Bsel_1668	8.609e-28	121.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,26NX5@186821|Sporolactobacillaceae	91061|Bacilli	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
LZS3_k127_4093297_2	643648.Slip_0836	6.643e-68	243.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42JJW@68298|Syntrophomonadaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS3_k127_4093297_4	1379698.RBG1_1C00001G0632	7.509e-25	108.0	COG1366@1|root,COG1366@2|Bacteria,2NRCS@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS3_k127_4093297_6	378806.STAUR_7590	1.799e-15	82.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,SpoIIE
LZS3_k127_4093297_7	485913.Krac_6991	0.0003281	53.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
LZS3_k127_4120988_12	314345.SPV1_12135	1.37e-17	82.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria	1224|Proteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS3_k127_4120988_2	1304888.ATWF01000001_gene1542	3.606e-287	899.0	COG0480@1|root,COG0480@2|Bacteria,2GFAG@200930|Deferribacteres	200930|Deferribacteres	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
LZS3_k127_4120988_6	945713.IALB_0908	5.935e-59	208.0	COG0049@1|root,COG0049@2|Bacteria	2|Bacteria	J	rRNA binding	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
LZS3_k127_4120988_5	909943.HIMB100_00002840	5.422e-61	213.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2U70K@28211|Alphaproteobacteria,4BQ5B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
LZS3_k127_4120988_0	1379698.RBG1_1C00001G1604	0.0	1868.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
LZS3_k127_4120988_11	880073.Calab_3296	1.237e-19	106.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
LZS3_k127_4120988_1	1254432.SCE1572_03070	0.0	1348.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2YUEA@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
LZS3_k127_4120988_8	1009370.ALO_08997	1.123e-40	155.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes	909932|Negativicutes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
LZS3_k127_4120988_9	373903.Hore_01070	4.185e-33	134.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WANA@53433|Halanaerobiales	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
LZS3_k127_4120988_3	649639.Bcell_0104	1.157e-89	308.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli,1ZB14@1386|Bacillus	91061|Bacilli	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
LZS3_k127_4120988_4	290512.Paes_0284	8.602e-62	217.0	COG0080@1|root,COG0080@2|Bacteria,1FDVE@1090|Chlorobi	1090|Chlorobi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
LZS3_k127_4120988_7	1379698.RBG1_1C00001G1610	6.07e-58	207.0	COG0250@1|root,COG0250@2|Bacteria,2NPAP@2323|unclassified Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
LZS3_k127_4120988_14	1150626.PHAMO_320002	1.06e-11	68.0	COG0690@1|root,COG0690@2|Bacteria,1N75P@1224|Proteobacteria,2UF51@28211|Alphaproteobacteria,2JTWP@204441|Rhodospirillales	204441|Rhodospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
LZS3_k127_4120988_13	1384484.AEQU_1447	2.684e-14	73.0	COG0267@1|root,COG0267@2|Bacteria,2GQFG@201174|Actinobacteria,4CWGB@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
LZS3_k127_4120988_10	204669.Acid345_1224	8.191e-25	104.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria,2JKFY@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS3_k127_4265412_4	552811.Dehly_0494	5.476e-140	460.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,34CJD@301297|Dehalococcoidia	301297|Dehalococcoidia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
LZS3_k127_4265412_12	697284.ERIC2_c39480	3.622e-70	242.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
LZS3_k127_4265412_9	1122132.AQYH01000010_gene4242	3.145e-90	310.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,4B71E@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
LZS3_k127_4265412_17	110319.CF8_2498	1.171e-52	198.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4DNTB@85009|Propionibacteriales	201174|Actinobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
LZS3_k127_4265412_21	1265313.HRUBRA_01170	2.086e-29	134.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria,1J637@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
LZS3_k127_4265412_3	867903.ThesuDRAFT_01418	2.989e-157	518.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3WCWI@538999|Clostridiales incertae sedis	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_4265412_16	269482.Bcep1808_4464	9.505e-54	212.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,1K2CE@119060|Burkholderiaceae	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
LZS3_k127_4265412_5	926569.ANT_01870	5.284e-127	420.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
LZS3_k127_4265412_7	1123075.AUDP01000006_gene2566	3.321e-107	362.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
LZS3_k127_4265412_18	1121346.KB899839_gene1172	1.095e-47	185.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli,26S1M@186822|Paenibacillaceae	91061|Bacilli	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
LZS3_k127_4265412_8	1397278.AYMV01000007_gene267	1.501e-92	319.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4FMBD@85023|Microbacteriaceae	201174|Actinobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2540c	Chorismate_synt
LZS3_k127_4265412_10	441620.Mpop_1589	6.676e-90	323.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,1JRB4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
LZS3_k127_4265412_19	868595.Desca_2131	1.183e-45	170.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,2621A@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
LZS3_k127_4265412_22	945713.IALB_0856	1.715e-24	109.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
LZS3_k127_4265412_20	1124780.ANNU01000013_gene3870	2.166e-33	142.0	COG2010@1|root,COG2010@2|Bacteria,4NMD5@976|Bacteroidetes,47R42@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
LZS3_k127_4265412_0	1191523.MROS_1104	0.0	1024.0	COG4263@1|root,COG4263@2|Bacteria	2|Bacteria	C	nitrous-oxide reductase activity	nosZ	GO:0000041,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0030001,GO:0042597,GO:0044464,GO:0051179,GO:0051234	1.7.2.4,1.9.3.1	ko:K00376,ko:K02275	ko00190,ko00910,ko01100,ko01120,map00190,map00910,map01100,map01120	M00155,M00529	R00081,R02804	RC00016,RC02861	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,Cupredoxin_1
LZS3_k127_4265412_11	1191523.MROS_1105	3.143e-75	272.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
LZS3_k127_4265412_6	1279009.ADICEAN_01491	5.617e-120	402.0	COG3420@1|root,COG3420@2|Bacteria,4NEGT@976|Bacteroidetes,47KEF@768503|Cytophagia	976|Bacteroidetes	P	Periplasmic copper-binding protein (NosD)	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
LZS3_k127_4265412_13	1279009.ADICEAN_01492	3.542e-66	243.0	COG1131@1|root,COG1131@2|Bacteria,4NG9T@976|Bacteroidetes,47PAA@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
LZS3_k127_4265412_15	1122176.KB903565_gene3235	5.83e-62	226.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1IPGQ@117747|Sphingobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
LZS3_k127_4265412_1	452637.Oter_0373	7.178e-215	677.0	COG1509@1|root,COG1509@2|Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA3	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
LZS3_k127_4265412_2	1163617.SCD_n00025	9.561e-189	598.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria	1224|Proteobacteria	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_4265412_14	395963.Bind_1161	3.528e-62	245.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3N9KJ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Sigma-54 interaction domain	hoxA	-	-	ko:K19641	ko02020,map02020	M00772	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_4323130_1	744872.Spica_2364	1.094e-08	67.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
LZS3_k127_4323130_2	1379698.RBG1_1C00001G1335	1.412e-08	69.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4323130_0	1123355.JHYO01000031_gene1566	2.249e-18	98.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,2UK9W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4385217_2	1278073.MYSTI_06425	2.192e-34	154.0	COG1075@1|root,COG1361@1|root,COG5492@1|root,COG1075@2|Bacteria,COG1361@2|Bacteria,COG5492@2|Bacteria,1P60C@1224|Proteobacteria,4395U@68525|delta/epsilon subdivisions,2X4CF@28221|Deltaproteobacteria,2YYRC@29|Myxococcales	28221|Deltaproteobacteria	N	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
LZS3_k127_4385217_4	643562.Daes_3109	1.927e-14	77.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2M86R@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
LZS3_k127_4385217_5	2880.D1J7B4	1.734e-06	56.0	COG0055@1|root,KOG1350@2759|Eukaryota	2759|Eukaryota	C	proton-transporting ATP synthase activity, rotational mechanism	atpB	GO:0000275,GO:0002376,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0005754,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008152,GO:0008270,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009409,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009544,GO:0009570,GO:0009579,GO:0009605,GO:0009607,GO:0009620,GO:0009628,GO:0009814,GO:0009817,GO:0009987,GO:0010035,GO:0010038,GO:0010287,GO:0010319,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0031976,GO:0031977,GO:0031984,GO:0032991,GO:0033178,GO:0034220,GO:0034357,GO:0034641,GO:0034654,GO:0042221,GO:0042623,GO:0042625,GO:0042626,GO:0042651,GO:0043167,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0045087,GO:0045259,GO:0045261,GO:0045267,GO:0046034,GO:0046390,GO:0046483,GO:0046689,GO:0046872,GO:0046914,GO:0046933,GO:0050832,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055035,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098542,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098807,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02112,ko:K02114,ko:K02133	ko00190,ko00195,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map00195,map01100,map04714,map05010,map05012,map05016	M00157,M00158	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N,ATP-synt_ab,ATP-synt_ab_N
LZS3_k127_4385217_1	65393.PCC7424_4990	2.243e-51	204.0	COG0784@1|root,COG3829@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria,3KJNP@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS3_k127_4385217_0	1379698.RBG1_1C00001G1816	9.355e-79	289.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
LZS3_k127_4385217_3	584708.Apau_2023	5.344e-26	116.0	COG0248@1|root,COG0248@2|Bacteria,3TB1X@508458|Synergistetes	508458|Synergistetes	FP	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
LZS3_k127_4438174_15	1120949.KB903333_gene1499	7.975e-05	52.0	COG4677@1|root,COG4677@2|Bacteria,2I2SF@201174|Actinobacteria,4DI5R@85008|Micromonosporales	201174|Actinobacteria	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
LZS3_k127_4438174_3	1380394.JADL01000004_gene6024	1.088e-52	190.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2U9AG@28211|Alphaproteobacteria,2JSU4@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
LZS3_k127_4438174_2	1210884.HG799465_gene12267	2.898e-60	227.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,CarboxypepD_reg,IAT_beta,Invasin_D3,PPC
LZS3_k127_4438174_10	1173028.ANKO01000127_gene4178	8.549e-16	86.0	COG0664@1|root,COG0664@2|Bacteria,1G07U@1117|Cyanobacteria,1H7SB@1150|Oscillatoriales	1117|Cyanobacteria	K	- catabolite gene activator and regulatory subunit of cAMP-dependent protein	ntcA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0032991,GO:0032993,GO:0043565,GO:0097159,GO:1901363	-	ko:K21561	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_4438174_9	96561.Dole_2317	6.896e-16	78.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4438174_5	562970.Btus_0849	1.294e-44	174.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli,278XQ@186823|Alicyclobacillaceae	91061|Bacilli	E	Alcohol dehydrogenase GroES-like domain	adh	-	1.1.1.1	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_4438174_4	1379270.AUXF01000001_gene2611	4.138e-46	174.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GerE,PocR,Response_reg
LZS3_k127_4438174_0	378806.STAUR_3895	3.109e-98	332.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,1R85W@1224|Proteobacteria	1224|Proteobacteria	M	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
LZS3_k127_4438174_7	926550.CLDAP_29650	7.465e-29	126.0	COG1503@1|root,COG1503@2|Bacteria,2G6UJ@200795|Chloroflexi	200795|Chloroflexi	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4438174_11	240015.ACP_3398	4.243e-12	68.0	2E34G@1|root,32Y4J@2|Bacteria,3Y5JB@57723|Acidobacteria,2JJW7@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4438174_1	1499967.BAYZ01000038_gene2269	8.731e-80	279.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,PAS_3,PAS_9
LZS3_k127_4438174_14	1499968.TCA2_0425	2.357e-05	53.0	COG4980@1|root,COG4980@2|Bacteria,1VK4M@1239|Firmicutes	1239|Firmicutes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
LZS3_k127_4438174_8	379066.GAU_3331	2.802e-24	112.0	COG0613@1|root,COG0613@2|Bacteria,1ZV9V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4438174_13	1191523.MROS_1743	3.666e-11	63.0	COG0272@1|root,COG0272@2|Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972,ko:K10754	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	M00289,M00295	R00382	RC00005	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
LZS3_k127_4462804_30	391625.PPSIR1_09331	9.129e-30	134.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_1532,iJN746.PP_3282	3HCDH,3HCDH_N
LZS3_k127_4462804_18	768066.HELO_3947	3.265e-71	259.0	COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria,1S0V9@1236|Gammaproteobacteria,1XN9H@135619|Oceanospirillales	135619|Oceanospirillales	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_4462804_21	1121405.dsmv_1217	4.476e-60	213.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
LZS3_k127_4462804_25	1255043.TVNIR_1704	4.907e-53	188.0	COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,1S809@1236|Gammaproteobacteria,1WZQ6@135613|Chromatiales	135613|Chromatiales	P	DsrE/DsrF-like family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
LZS3_k127_4462804_8	1299327.I546_1123	6.006e-144	466.0	COG0446@1|root,COG0446@2|Bacteria,2IB5R@201174|Actinobacteria	201174|Actinobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
LZS3_k127_4462804_17	404589.Anae109_3258	2.754e-75	259.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,42SBN@68525|delta/epsilon subdivisions,2WP4A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Rhodanese domain protein	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,Rhodanese
LZS3_k127_4462804_45	1121930.AQXG01000002_gene2126	1.94e-07	64.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IPVJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
LZS3_k127_4462804_10	247490.KSU1_C0449	1.244e-108	375.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_4462804_38	880073.Calab_2081	1.107e-20	106.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_4462804_20	278957.ABEA03000004_gene4502	2.501e-60	228.0	COG1262@1|root,COG1262@2|Bacteria,46VAM@74201|Verrucomicrobia,3K9HB@414999|Opitutae	414999|Opitutae	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,VPEP
LZS3_k127_4462804_31	1232410.KI421426_gene1504	4.652e-29	119.0	2DXYD@1|root,3476T@2|Bacteria,1NCGD@1224|Proteobacteria	1224|Proteobacteria	S	Sugar efflux transporter for intercellular exchange	-	-	-	-	-	-	-	-	-	-	-	-	MtN3_slv
LZS3_k127_4462804_27	1232410.KI421421_gene3301	2.046e-41	154.0	COG0640@1|root,COG0640@2|Bacteria,1NCXP@1224|Proteobacteria,42TJG@68525|delta/epsilon subdivisions,2WSYR@28221|Deltaproteobacteria,43VCK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4462804_22	269799.Gmet_1792	4.458e-57	207.0	2B0BZ@1|root,31SP3@2|Bacteria,1RM1T@1224|Proteobacteria,42RVA@68525|delta/epsilon subdivisions,2WR20@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4462804_26	472759.Nhal_2122	4.882e-48	179.0	COG0702@1|root,COG0702@2|Bacteria,1QV7M@1224|Proteobacteria,1T2N4@1236|Gammaproteobacteria,1WYK0@135613|Chromatiales	135613|Chromatiales	GM	intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
LZS3_k127_4462804_15	1192034.CAP_2122	1.338e-78	292.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_4462804_43	1121930.AQXG01000004_gene2870	1.992e-12	81.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
LZS3_k127_4462804_13	1192034.CAP_3762	1.533e-81	299.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2YZYM@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_4462804_40	880073.Calab_0921	1.131e-17	98.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_4462804_16	1192034.CAP_2122	7.191e-77	289.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_4462804_41	1121930.AQXG01000001_gene1216	1.735e-15	91.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Beta_helix,F5_F8_type_C
LZS3_k127_4462804_23	526225.Gobs_1160	1.641e-56	222.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales	201174|Actinobacteria	P	WD-40 repeat-containing protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,TIR_2,WD40
LZS3_k127_4462804_5	1201288.M900_1475	2.339e-163	527.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2MUQC@213481|Bdellovibrionales,2WJQQ@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
LZS3_k127_4462804_33	1151122.AQYD01000006_gene2366	3.398e-27	120.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria,4FNZB@85023|Microbacteriaceae	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
LZS3_k127_4462804_42	880073.Calab_0829	6.647e-13	81.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane
LZS3_k127_4462804_14	765952.PUV_08470	2.96e-79	274.0	COG3271@1|root,COG3271@2|Bacteria,2JGZU@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4462804_3	1232410.KI421415_gene2975	1.932e-175	562.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria,43UK8@69541|Desulfuromonadales	28221|Deltaproteobacteria	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
LZS3_k127_4462804_7	1232410.KI421415_gene2974	3.774e-145	473.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria,43UJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
LZS3_k127_4462804_19	314230.DSM3645_07465	7.593e-66	237.0	COG3931@1|root,COG3931@2|Bacteria,2J373@203682|Planctomycetes	203682|Planctomycetes	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
LZS3_k127_4462804_34	290397.Adeh_4042	2.068e-22	104.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS3_k127_4462804_12	929703.KE386491_gene1445	2.786e-87	305.0	COG0038@1|root,COG0038@2|Bacteria,4NFCF@976|Bacteroidetes,47JTU@768503|Cytophagia	976|Bacteroidetes	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	TrkA_C,Voltage_CLC
LZS3_k127_4462804_35	945713.IALB_2396	9.408e-22	113.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
LZS3_k127_4462804_39	518766.Rmar_0744	3.646e-18	101.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1FKAM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS3_k127_4462804_32	1121930.AQXG01000004_gene2869	4.487e-28	131.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	prtA	-	3.2.1.23,3.4.24.40	ko:K01190,ko:K01406,ko:K07004,ko:K13277	ko00052,ko00511,ko00600,ko01100,ko01503,ko02024,map00052,map00511,map00600,map01100,map01503,map02024	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Gram_pos_anchor,HemolysinCabind,PA,Peptidase_S8,SLH,fn3_5
LZS3_k127_4462804_46	436229.JOEH01000013_gene5874	0.0003244	53.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria,2NEPB@228398|Streptacidiphilus	201174|Actinobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
LZS3_k127_4462804_28	671065.MetMK1DRAFT_00016460	2.97e-34	147.0	COG0183@1|root,arCOG01278@2157|Archaea,2XPZV@28889|Crenarchaeota	28889|Crenarchaeota	I	PFAM Thiolase	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_4462804_6	99598.Cal7507_5042	1.059e-149	486.0	COG1960@1|root,COG1960@2|Bacteria,1G4K8@1117|Cyanobacteria,1HU4P@1161|Nostocales	1117|Cyanobacteria	I	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_4462804_29	1144275.COCOR_02593	1.085e-31	132.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,42NH4@68525|delta/epsilon subdivisions,2WN7A@28221|Deltaproteobacteria,2YTZA@29|Myxococcales	28221|Deltaproteobacteria	Q	non-ribosomal peptide synthetase	-	-	-	ko:K16416	ko01052,map01052	-	-	-	ko00000,ko00001,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
LZS3_k127_4462804_9	76114.ebA4326	1.047e-121	403.0	COG1020@1|root,COG1020@2|Bacteria,1QK4F@1224|Proteobacteria,2VHRU@28216|Betaproteobacteria,2KW0H@206389|Rhodocyclales	206389|Rhodocyclales	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Hexapep,PP-binding
LZS3_k127_4462804_36	886293.Sinac_1596	1.171e-21	97.0	COG0236@1|root,COG0236@2|Bacteria,2J1MP@203682|Planctomycetes	203682|Planctomycetes	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
LZS3_k127_4462804_4	76114.ebA4323	5.581e-174	576.0	COG1696@1|root,COG1696@2|Bacteria	2|Bacteria	M	negative regulation of protein lipidation	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
LZS3_k127_4462804_11	1499967.BAYZ01000119_gene3214	2.101e-97	327.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
LZS3_k127_4462804_0	1191523.MROS_2798	0.0	1121.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
LZS3_k127_4462804_2	1499967.BAYZ01000119_gene3216	4.776e-200	638.0	COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
LZS3_k127_4462804_1	1499967.BAYZ01000081_gene1057	3.208e-214	672.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
LZS3_k127_4462804_24	797299.HALLA_15630	1.526e-53	210.0	COG0367@1|root,arCOG00121@2157|Archaea,2XVTD@28890|Euryarchaeota,23TT1@183963|Halobacteria	183963|Halobacteria	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS3_k127_4462804_37	1205910.B005_2791	2.136e-21	110.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4EIFG@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_4462804_44	644282.Deba_3075	1.398e-07	63.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS3_k127_4561363_61	113395.AXAI01000007_gene1458	2.088e-65	229.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
LZS3_k127_4561363_87	1448139.AI20_10355	2.893e-41	165.0	COG0607@1|root,COG0607@2|Bacteria,1MZ87@1224|Proteobacteria,1S98V@1236|Gammaproteobacteria,1Y5TJ@135624|Aeromonadales	135624|Aeromonadales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS3_k127_4561363_75	1242864.D187_004989	4.512e-57	210.0	COG1739@1|root,COG1739@2|Bacteria,1NFJC@1224|Proteobacteria,42T7W@68525|delta/epsilon subdivisions,2WNWV@28221|Deltaproteobacteria,2Z23H@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1949)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
LZS3_k127_4561363_56	13035.Dacsa_3298	6.897e-78	269.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
LZS3_k127_4561363_84	1128421.JAGA01000003_gene2807	4.504e-44	164.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	-
LZS3_k127_4561363_28	1283300.ATXB01000002_gene2986	5.514e-140	461.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria,1XED8@135618|Methylococcales	135618|Methylococcales	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DAO_C
LZS3_k127_4561363_30	880073.Calab_0806	7.529e-129	419.0	COG1351@1|root,COG1351@2|Bacteria,2NPQ2@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
LZS3_k127_4561363_70	59374.Fisuc_1317	2.09e-60	216.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	lpoB	GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K07337,ko:K21008	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	LpoB
LZS3_k127_4561363_95	330214.NIDE1648	3.406e-36	154.0	COG3014@1|root,COG3014@2|Bacteria,3J14B@40117|Nitrospirae	40117|Nitrospirae	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
LZS3_k127_4561363_5	690850.Desaf_3768	3.738e-235	754.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2M8CA@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
LZS3_k127_4561363_65	1191523.MROS_0039	9.557e-63	225.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	sco	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS3_k127_4561363_3	945713.IALB_1394	7.099e-240	751.0	COG0843@1|root,COG0843@2|Bacteria	2|Bacteria	C	heme-copper terminal oxidase activity	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
LZS3_k127_4561363_68	945713.IALB_1395	3.964e-61	220.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
LZS3_k127_4561363_116	1232410.KI421415_gene2987	2.198e-15	79.0	2EAMQ@1|root,334Q9@2|Bacteria,1NA2T@1224|Proteobacteria,42VC9@68525|delta/epsilon subdivisions,2WRD9@28221|Deltaproteobacteria,43SRT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	coxD	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
LZS3_k127_4561363_50	1168034.FH5T_09805	1.392e-85	293.0	COG1622@1|root,COG1622@2|Bacteria,4NFNF@976|Bacteroidetes,2FX9N@200643|Bacteroidia	976|Bacteroidetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
LZS3_k127_4561363_76	1121920.AUAU01000026_gene1433	6.726e-56	206.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
LZS3_k127_4561363_96	1191523.MROS_0033	1.578e-35	152.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Copper-bind,Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,Lipase_GDSL_2,PSCyt1
LZS3_k127_4561363_78	1232410.KI421425_gene1566	4.247e-50	185.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2X7M4@28221|Deltaproteobacteria,43VY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4561363_2	1232410.KI421425_gene1565	4.586e-264	842.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,43TY6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
LZS3_k127_4561363_16	338963.Pcar_2552	1.777e-166	537.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
LZS3_k127_4561363_115	338963.Pcar_2553	5.256e-18	96.0	COG2010@1|root,COG2010@2|Bacteria,1PWTD@1224|Proteobacteria,437B9@68525|delta/epsilon subdivisions,2X9ZG@28221|Deltaproteobacteria,43V90@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
LZS3_k127_4561363_83	1232410.KI421425_gene1562	7.605e-45	181.0	COG5557@1|root,COG5557@2|Bacteria,1QURB@1224|Proteobacteria,43BT1@68525|delta/epsilon subdivisions,2X73S@28221|Deltaproteobacteria,43SR9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pfam Polysulphide reductase, NrfD	actF	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4561363_82	1322246.BN4_12726	1.403e-45	170.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2MBR8@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
LZS3_k127_4561363_94	511680.BUTYVIB_01234	2.82e-37	150.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,4BZ3J@830|Butyrivibrio	186801|Clostridia	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
LZS3_k127_4561363_52	158190.SpiGrapes_0643	3.616e-83	293.0	COG0052@1|root,COG0052@2|Bacteria,2J5GZ@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
LZS3_k127_4561363_58	880073.Calab_2291	5.286e-73	259.0	COG0264@1|root,COG0264@2|Bacteria,2NP3B@2323|unclassified Bacteria	2|Bacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
LZS3_k127_4561363_46	913865.DOT_4422	1.692e-92	310.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,260FG@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
LZS3_k127_4561363_67	1307759.JOMJ01000003_gene241	1.834e-61	216.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2M8XC@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
LZS3_k127_4561363_55	246194.CHY_1781	2.184e-79	272.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,42F7X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
LZS3_k127_4561363_88	671143.DAMO_0675	4.223e-41	164.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
LZS3_k127_4561363_39	717605.Theco_2065	9.186e-100	338.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,26S2E@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
LZS3_k127_4561363_71	1232410.KI421418_gene2269	6.426e-60	229.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,43S7D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
LZS3_k127_4561363_74	690850.Desaf_2757	1.074e-57	225.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2M8BJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS3_k127_4561363_113	927658.AJUM01000040_gene898	1.007e-18	103.0	COG2911@1|root,COG2911@2|Bacteria,4NSGX@976|Bacteroidetes,2FWBM@200643|Bacteroidia,3XJUG@558415|Marinilabiliaceae	976|Bacteroidetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA,TamB
LZS3_k127_4561363_20	1379698.RBG1_1C00001G0340	1.534e-159	543.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
LZS3_k127_4561363_11	411468.CLOSCI_02849	3.704e-183	599.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,21Y37@1506553|Lachnoclostridium	186801|Clostridia	L	UvrD-like helicase C-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
LZS3_k127_4561363_120	710685.MycrhN_5936	8.077e-12	78.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,239Z5@1762|Mycobacteriaceae	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
LZS3_k127_4561363_18	240015.ACP_1864	1.447e-165	537.0	COG0154@1|root,COG0154@2|Bacteria,3Y2PE@57723|Acidobacteria,2JIE0@204432|Acidobacteriia	204432|Acidobacteriia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
LZS3_k127_4561363_26	1335757.SPICUR_07925	1.222e-143	472.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
LZS3_k127_4561363_107	290397.Adeh_2115	2.673e-27	124.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS3_k127_4561363_105	96561.Dole_1704	2.005e-28	133.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4561363_126	483219.LILAB_13705	0.0001157	50.0	COG0515@1|root,COG0515@2|Bacteria	483219.LILAB_13705|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
LZS3_k127_4561363_124	309807.SRU_1916	2.017e-06	61.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,4PM65@976|Bacteroidetes,1FKEM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
LZS3_k127_4561363_119	1122225.AULQ01000003_gene885	7.195e-12	74.0	COG1506@1|root,COG4935@1|root,COG1506@2|Bacteria,COG4935@2|Bacteria,4NQQD@976|Bacteroidetes,1I3SI@117743|Flavobacteriia	976|Bacteroidetes	E	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,LTD
LZS3_k127_4561363_59	379066.GAU_1710	5.51e-71	253.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
LZS3_k127_4561363_79	1379270.AUXF01000006_gene183	2.745e-49	180.0	COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
LZS3_k127_4561363_31	1449126.JQKL01000002_gene1595	9.102e-128	419.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_4561363_27	1379698.RBG1_1C00001G1459	9.555e-141	457.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_4561363_37	518766.Rmar_0752	1.023e-109	365.0	COG1250@1|root,COG1250@2|Bacteria,4NGU8@976|Bacteroidetes,1FJ15@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
LZS3_k127_4561363_93	1283299.AUKG01000001_gene1898	1.907e-37	146.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,4CQ97@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
LZS3_k127_4561363_8	1123405.AUMM01000010_gene1224	6.099e-213	679.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,26P9A@186821|Sporolactobacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
LZS3_k127_4561363_111	861299.J421_3415	2.948e-21	101.0	COG4770@1|root,COG4770@2|Bacteria,1ZTVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
LZS3_k127_4561363_21	1313301.AUGC01000001_gene1642	1.032e-156	509.0	COG4770@1|root,COG4770@2|Bacteria,4NM1W@976|Bacteroidetes	976|Bacteroidetes	I	PFAM Carbamoyl-phosphate synthase L chain, ATP binding	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS3_k127_4561363_6	234267.Acid_1492	1.034e-230	723.0	COG4799@1|root,COG4799@2|Bacteria,3Y3SM@57723|Acidobacteria	57723|Acidobacteria	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
LZS3_k127_4561363_104	1122176.KB903587_gene4485	6.836e-29	136.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,4PPP2@976|Bacteroidetes,1IZ5Q@117747|Sphingobacteriia	976|Bacteroidetes	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4561363_109	880073.Calab_1973	1.745e-23	118.0	COG2911@1|root,COG4447@1|root,COG2911@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.4	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	CBM_X2,fn3
LZS3_k127_4561363_118	335543.Sfum_3888	1.477e-13	85.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MSG5@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase, family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
LZS3_k127_4561363_35	1033740.CAEW01000024_gene1477	4.773e-121	400.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,26D7U@186818|Planococcaceae	91061|Bacilli	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_4561363_43	1379698.RBG1_1C00001G0510	3.463e-94	318.0	COG1250@1|root,COG1250@2|Bacteria,2NP11@2323|unclassified Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
LZS3_k127_4561363_51	1121920.AUAU01000004_gene629	6.956e-84	285.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria	57723|Acidobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
LZS3_k127_4561363_23	1191523.MROS_2438	4.388e-150	484.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	gcdH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_4561363_32	1379698.RBG1_1C00001G0508	1.859e-126	417.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	bktB	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_4561363_25	1379698.RBG1_1C00001G0516	2.161e-146	473.0	COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria	2|Bacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS3_k127_4561363_64	1125863.JAFN01000001_gene3467	6.993e-64	238.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
LZS3_k127_4561363_49	243274.THEMA_01190	5.834e-89	298.0	COG0740@1|root,COG0740@2|Bacteria,2GC7E@200918|Thermotogae	200918|Thermotogae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
LZS3_k127_4561363_14	1294142.CINTURNW_2900	9.583e-170	542.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,36EA3@31979|Clostridiaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
LZS3_k127_4561363_1	1121468.AUBR01000001_gene487	2.616e-265	839.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS3_k127_4561363_4	118163.Ple7327_3116	1.299e-238	755.0	COG0365@1|root,COG0365@2|Bacteria,1G112@1117|Cyanobacteria,3VHSF@52604|Pleurocapsales	1117|Cyanobacteria	I	AMP-binding enzyme	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS3_k127_4561363_81	1122146.AUHP01000009_gene861	2.737e-47	177.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,3F44G@33958|Lactobacillaceae	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
LZS3_k127_4561363_47	671143.DAMO_3099	4.379e-92	316.0	COG0075@1|root,COG0075@2|Bacteria,2NP52@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-V	-	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS3_k127_4561363_41	1121468.AUBR01000059_gene896	1.299e-95	329.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,42EYX@68295|Thermoanaerobacterales	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
LZS3_k127_4561363_34	653733.Selin_0177	9.712e-124	410.0	COG0104@1|root,COG0104@2|Bacteria	2|Bacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_4393,iECSF_1327.ECSF_4063,iJN746.PP_4889	Adenylsucc_synt
LZS3_k127_4561363_89	313603.FB2170_11511	1.234e-40	164.0	COG2897@1|root,COG2897@2|Bacteria,4NJGQ@976|Bacteroidetes,1HYM5@117743|Flavobacteriia	976|Bacteroidetes	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS3_k127_4561363_62	880073.Calab_1603	3.422e-65	237.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
LZS3_k127_4561363_114	478741.JAFS01000001_gene1168	3.49e-18	100.0	COG1309@1|root,COG1309@2|Bacteria,46T6V@74201|Verrucomicrobia,37GQP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Bacterial regulatory proteins, tetR family	acrR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
LZS3_k127_4561363_86	264732.Moth_1872	4.441e-42	179.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS3_k127_4561363_98	1121468.AUBR01000016_gene2342	2.086e-33	138.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,42G7Y@68295|Thermoanaerobacterales	186801|Clostridia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
LZS3_k127_4561363_13	404589.Anae109_3444	3.376e-173	554.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria,2Z3J1@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
LZS3_k127_4561363_38	1191523.MROS_0148	2.029e-103	349.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
LZS3_k127_4561363_36	493475.GARC_2786	2.953e-116	388.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,466RG@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS3_k127_4561363_44	493475.GARC_2785	7.683e-94	314.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,4673X@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ATPases associated with a variety of cellular activities	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_4561363_22	493475.GARC_2784	4.241e-154	496.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,468D5@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_4561363_19	493475.GARC_2783	1.08e-159	515.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,468D5@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_4561363_24	1227739.Hsw_3004	8.972e-149	482.0	COG0332@1|root,COG0332@2|Bacteria,4NEZE@976|Bacteroidetes,47MUI@768503|Cytophagia	976|Bacteroidetes	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS3_k127_4561363_73	1047013.AQSP01000134_gene1339	9.224e-58	209.0	COG5012@1|root,COG5012@2|Bacteria,2NQTJ@2323|unclassified Bacteria	2|Bacteria	S	B12 binding domain	-	-	-	ko:K14084	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124	RC00035,RC00732,RC02984	ko00000,ko00001,ko00002	-	-	-	B12-binding,B12-binding_2
LZS3_k127_4561363_72	1047013.AQSP01000134_gene1366	1.192e-59	217.0	COG0646@1|root,COG0646@2|Bacteria,2NP9A@2323|unclassified Bacteria	2|Bacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
LZS3_k127_4561363_110	555088.DealDRAFT_2256	4.612e-23	110.0	COG1410@1|root,COG1410@2|Bacteria,1V7JJ@1239|Firmicutes,24AE1@186801|Clostridia	186801|Clostridia	E	vitamin B12 dependent methionine synthase, activation	metH2	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
LZS3_k127_4561363_29	1047013.AQSP01000134_gene1338	1.871e-131	436.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
LZS3_k127_4561363_69	1499967.BAYZ01000164_gene6670	9.916e-61	220.0	COG3907@1|root,COG3907@2|Bacteria	2|Bacteria	S	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
LZS3_k127_4561363_97	1116472.MGMO_152c00140	2.435e-34	140.0	2CKY4@1|root,33K9I@2|Bacteria,1R395@1224|Proteobacteria,1T652@1236|Gammaproteobacteria,1XF7F@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4561363_100	472759.Nhal_0415	3.845e-31	130.0	COG4659@1|root,COG4659@2|Bacteria,1RFGW@1224|Proteobacteria,1S603@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
LZS3_k127_4561363_45	1125863.JAFN01000001_gene2230	1.26e-92	321.0	COG2433@1|root,COG2433@2|Bacteria,1QW3W@1224|Proteobacteria,42RB0@68525|delta/epsilon subdivisions,2WN8G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4561363_112	694429.Pyrfu_1309	3.06e-20	96.0	COG1321@1|root,arCOG02100@2157|Archaea	2157|Archaea	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress
LZS3_k127_4561363_57	96561.Dole_0404	7.617e-77	266.0	COG0357@1|root,COG0566@1|root,COG0357@2|Bacteria,COG0566@2|Bacteria,1QW0W@1224|Proteobacteria,43BQS@68525|delta/epsilon subdivisions,2WMFV@28221|Deltaproteobacteria,2MN58@213118|Desulfobacterales	28221|Deltaproteobacteria	JM	rRNA small subunit methyltransferase G	-	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB,SpoU_methylase
LZS3_k127_4561363_53	1121406.JAEX01000016_gene1885	1.966e-82	299.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
LZS3_k127_4561363_117	1243664.CAVL020000056_gene2364	1.332e-13	82.0	COG0438@1|root,COG0438@2|Bacteria,1V4TS@1239|Firmicutes,4HC19@91061|Bacilli,1ZIBP@1386|Bacillus	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
LZS3_k127_4561363_92	926561.KB900617_gene2098	6.632e-38	155.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gt2F	-	2.4.1.175,2.4.1.226	ko:K13500	ko00532,ko01100,map00532,map01100	-	R04603,R05931,R05932,R05933,R05934,R07336	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_transf_7C,Glycos_transf_2
LZS3_k127_4561363_66	1047013.AQSP01000138_gene1052	1.107e-62	226.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	waaE	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glyco_transf_7C,Glycos_transf_2
LZS3_k127_4561363_7	330214.NIDE0577	6.321e-221	739.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
LZS3_k127_4561363_63	1158338.JNLJ01000001_gene905	4.031e-64	231.0	COG2885@1|root,COG2885@2|Bacteria,2G4S4@200783|Aquificae	200783|Aquificae	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_YMGG,OmpA,TSP_3
LZS3_k127_4561363_48	1382356.JQMP01000004_gene499	1.699e-91	324.0	COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi,27Y3N@189775|Thermomicrobia	189775|Thermomicrobia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_4561363_90	379066.GAU_2622	2.099e-40	162.0	COG1597@1|root,COG1597@2|Bacteria,1ZU66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
LZS3_k127_4561363_42	351627.Csac_1225	7.058e-95	329.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,42FUG@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Aminotransferase class I and II	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47,6.2.1.14	ko:K00639,ko:K00652,ko:K01906	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03209,R03210,R10124	RC00004,RC00014,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_4561363_121	221027.JO40_09175	1.745e-10	73.0	COG0204@1|root,COG0204@2|Bacteria,2J6B7@203691|Spirochaetes	203691|Spirochaetes	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_4561363_108	1207076.ALAT01000207_gene1725	3.782e-24	115.0	COG1597@1|root,COG1597@2|Bacteria,1RB97@1224|Proteobacteria,1S4B3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Mmp37
LZS3_k127_4561363_99	1297742.A176_00909	2.151e-32	136.0	COG0558@1|root,COG2246@1|root,COG0558@2|Bacteria,COG2246@2|Bacteria,1N9TT@1224|Proteobacteria,42V2Q@68525|delta/epsilon subdivisions,2WRYY@28221|Deltaproteobacteria,2YWYE@29|Myxococcales	28221|Deltaproteobacteria	I	GtrA-like protein	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,GtrA
LZS3_k127_4561363_10	156578.ATW7_03352	4.896e-189	621.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RYP9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	aminopeptidase	-	-	3.4.11.14,3.4.11.2	ko:K01256,ko:K01263	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
LZS3_k127_4561363_101	671143.DAMO_1476	5.01e-31	124.0	COG5470@1|root,COG5470@2|Bacteria,2NQ81@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
LZS3_k127_4561363_15	502025.Hoch_6598	1.247e-166	535.0	COG0493@1|root,COG0493@2|Bacteria,1P58U@1224|Proteobacteria,4392A@68525|delta/epsilon subdivisions,2X47Z@28221|Deltaproteobacteria,2YYG2@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
LZS3_k127_4561363_9	1124780.ANNU01000078_gene769	1.421e-201	641.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
LZS3_k127_4561363_91	401053.AciPR4_3251	1.48e-39	158.0	COG2318@1|root,COG2318@2|Bacteria,3Y81K@57723|Acidobacteria,2JN5E@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS3_k127_4561363_17	1089550.ATTH01000001_gene2135	1.354e-165	534.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1FIWH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
LZS3_k127_4561363_123	1121104.AQXH01000005_gene164	3.311e-08	68.0	COG1404@1|root,COG5276@1|root,COG1404@2|Bacteria,COG5276@2|Bacteria,4PPJ4@976|Bacteroidetes,1IZ3E@117747|Sphingobacteriia	2|Bacteria	O	Protein conserved in bacteria	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FG-GAP,LVIVD,Peptidase_S8,Phytase-like,SLH,TSP_3
LZS3_k127_4561363_60	330084.JNYZ01000008_gene6694	4.373e-70	272.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,Calx-beta,HemolysinCabind
LZS3_k127_4561363_103	1121479.AUBS01000001_gene3188	1.453e-29	128.0	2CA4Z@1|root,32W4Q@2|Bacteria,1N3RF@1224|Proteobacteria,2UDC8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4561363_0	768671.ThimaDRAFT_0214	0.0	1324.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,1RQA8@1236|Gammaproteobacteria,1WW62@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
LZS3_k127_4561363_54	309800.C498_17770	1.55e-81	278.0	COG1028@1|root,arCOG01259@2157|Archaea,2XUNT@28890|Euryarchaeota,23U46@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_4561363_85	237609.PSAKL28_24720	2.261e-43	164.0	COG1846@1|root,COG1846@2|Bacteria,1RF3U@1224|Proteobacteria,1S4H8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
LZS3_k127_4561363_40	330214.NIDE3709	1.033e-96	332.0	COG0500@1|root,COG2226@2|Bacteria,3J12W@40117|Nitrospirae	40117|Nitrospirae	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
LZS3_k127_4561363_102	1121920.AUAU01000017_gene1208	3.112e-30	133.0	COG2234@1|root,COG2234@2|Bacteria,3Y4CJ@57723|Acidobacteria	57723|Acidobacteria	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS3_k127_4561363_33	768671.ThimaDRAFT_0215	3.475e-124	414.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,1S28B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	nucleotidyltransferase DNA polymerase involved in DNA repair	imuB	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
LZS3_k127_4561363_80	861299.J421_1688	7.009e-48	195.0	COG1075@1|root,COG2124@1|root,COG1075@2|Bacteria,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	Abhydrolase_8,PGAP1,p450
LZS3_k127_4561363_125	459349.CLOAM1520	2.847e-06	61.0	COG4412@1|root,COG4412@2|Bacteria,2NQZW@2323|unclassified Bacteria	2|Bacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,W_rich_C,fn3
LZS3_k127_4561363_106	314230.DSM3645_12431	4.41e-28	127.0	COG3070@1|root,COG3070@2|Bacteria,2J0Y3@203682|Planctomycetes	203682|Planctomycetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
LZS3_k127_4561363_77	765912.Thimo_1621	6.192e-51	188.0	COG0468@1|root,COG0468@2|Bacteria,1RIBX@1224|Proteobacteria,1SN7I@1236|Gammaproteobacteria,1X0NV@135613|Chromatiales	135613|Chromatiales	L	recA bacterial DNA recombination protein	-	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
LZS3_k127_4561363_12	1499967.BAYZ01000036_gene2418	4.891e-181	571.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_4571368_1	1089550.ATTH01000001_gene1531	1.643e-13	72.0	COG2911@1|root,COG3210@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,4NTNN@976|Bacteroidetes	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
LZS3_k127_4571368_0	997884.HMPREF1068_00362	3.081e-89	335.0	COG1361@1|root,COG1520@1|root,COG4870@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia,4ATRZ@815|Bacteroidaceae	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
LZS3_k127_4572722_4	1501230.ET33_32490	3.195e-173	554.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4HB80@91061|Bacilli,26RUP@186822|Paenibacillaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS3_k127_4572722_51	933115.GPDM_10360	1.728e-71	253.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,26EWK@186818|Planococcaceae	91061|Bacilli	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS3_k127_4572722_57	1322246.BN4_11289	4.862e-62	236.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2M8HR@213115|Desulfovibrionales	28221|Deltaproteobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS3_k127_4572722_20	1293054.HSACCH_00336	6.261e-121	399.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WAG7@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain	-	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS3_k127_4572722_18	378806.STAUR_5445	4.167e-131	426.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,2YU5K@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
LZS3_k127_4572722_38	1379698.RBG1_1C00001G1820	2.274e-82	308.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_4572722_64	518766.Rmar_0357	3.588e-51	194.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	UPF0164
LZS3_k127_4572722_107	1519464.HY22_11300	8.531e-12	78.0	COG4219@1|root,COG4219@2|Bacteria,1FF12@1090|Chlorobi	1090|Chlorobi	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4572722_62	880073.Calab_2424	1.279e-52	198.0	COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS3_k127_4572722_100	1121904.ARBP01000002_gene7281	5.399e-13	74.0	COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes	976|Bacteroidetes	U	Pfam Biopolymer transport protein ExbD TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
LZS3_k127_4572722_94	1191523.MROS_2569	3.849e-19	93.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS3_k127_4572722_101	1121930.AQXG01000003_gene2554	1.388e-12	78.0	COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes	976|Bacteroidetes	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS3_k127_4572722_104	1122236.KB905146_gene1882	3.803e-12	73.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria,2KMXT@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS3_k127_4572722_77	1191523.MROS_2280	8.49e-35	149.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
LZS3_k127_4572722_32	402612.FP0584	1.212e-93	313.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1HXPP@117743|Flavobacteriia,2NTAX@237|Flavobacterium	976|Bacteroidetes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_4572722_42	1379698.RBG1_1C00001G1364	1.387e-77	276.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
LZS3_k127_4572722_53	1379698.RBG1_1C00001G1366	1.805e-70	254.0	COG0577@1|root,COG0577@2|Bacteria,2NQMU@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_4572722_44	1379698.RBG1_1C00001G1367	8.421e-77	272.0	COG0577@1|root,COG0577@2|Bacteria,2NNN0@2323|unclassified Bacteria	2|Bacteria	V	COGs COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_4572722_82	1379698.RBG1_1C00001G1368	2.735e-31	138.0	COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria	2|Bacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
LZS3_k127_4572722_26	1379270.AUXF01000004_gene3277	4.246e-102	351.0	COG4166@1|root,COG4166@2|Bacteria,1ZSMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS3_k127_4572722_27	1379270.AUXF01000004_gene3278	1.027e-99	334.0	COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS3_k127_4572722_40	379066.GAU_0641	6.146e-79	278.0	COG1173@1|root,COG1173@2|Bacteria,1ZT0U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
LZS3_k127_4572722_76	243090.RB11119	7.553e-37	159.0	COG0791@1|root,COG0791@2|Bacteria,2J4V8@203682|Planctomycetes	203682|Planctomycetes	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
LZS3_k127_4572722_105	497964.CfE428DRAFT_0616	3.806e-12	79.0	COG0705@1|root,COG0705@2|Bacteria,46SYD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS3_k127_4572722_55	1382358.JHVN01000011_gene1933	8.729e-67	236.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,21UYR@150247|Anoxybacillus	91061|Bacilli	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
LZS3_k127_4572722_12	1379698.RBG1_1C00001G1860	1.254e-144	465.0	COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria	2|Bacteria	D	MreB/Mbl protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
LZS3_k127_4572722_84	59374.Fisuc_1901	1.757e-28	125.0	COG1792@1|root,COG1792@2|Bacteria	2|Bacteria	M	regulation of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
LZS3_k127_4572722_109	1121428.DESHY_120043___1	4.959e-09	64.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24RP5@186801|Clostridia,262R9@186807|Peptococcaceae	186801|Clostridia	M	shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
LZS3_k127_4572722_25	880073.Calab_1721	1.261e-109	377.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
LZS3_k127_4572722_33	1379698.RBG1_1C00001G1004	2.346e-90	317.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
LZS3_k127_4572722_65	1379698.RBG1_1C00001G1006	6.08e-50	188.0	COG0682@1|root,COG0682@2|Bacteria,2NPK2@2323|unclassified Bacteria	2|Bacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
LZS3_k127_4572722_96	796942.HMPREF9623_01032	7.535e-17	94.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
LZS3_k127_4572722_14	479437.Elen_1779	1.558e-139	451.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CUJP@84998|Coriobacteriia	84998|Coriobacteriia	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
LZS3_k127_4572722_13	945713.IALB_1271	1.418e-144	468.0	COG0126@1|root,COG0126@2|Bacteria	2|Bacteria	F	phosphoglycerate kinase activity	pgk	GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
LZS3_k127_4572722_46	215803.DB30_3034	1.245e-75	263.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,2YU88@29|Myxococcales	28221|Deltaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
LZS3_k127_4572722_98	96561.Dole_0498	4.255e-14	78.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2MKYR@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
LZS3_k127_4572722_15	269799.Gmet_0138	3.673e-136	449.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
LZS3_k127_4572722_99	1469948.JPNB01000002_gene3377	1.313e-13	78.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,36IVR@31979|Clostridiaceae	186801|Clostridia	D	Protein of unknown function (DUF4446)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
LZS3_k127_4572722_59	1379698.RBG1_1C00001G1850	3.984e-55	206.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
LZS3_k127_4572722_72	944481.JAFP01000001_gene1050	3.572e-41	155.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2M7A3@213113|Desulfurellales	28221|Deltaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
LZS3_k127_4572722_31	484770.UFO1_1578	7.056e-97	340.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS3_k127_4572722_37	1499967.BAYZ01000054_gene4817	4.88e-85	292.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
LZS3_k127_4572722_52	582744.Msip34_1455	1.293e-70	250.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2WESV@28216|Betaproteobacteria,2KMEI@206350|Nitrosomonadales	206350|Nitrosomonadales	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
LZS3_k127_4572722_35	290397.Adeh_4045	2.709e-86	297.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
LZS3_k127_4572722_61	1379698.RBG1_1C00001G1352	3.081e-54	206.0	COG0428@1|root,COG0428@2|Bacteria,2NQ6J@2323|unclassified Bacteria	2|Bacteria	P	ZIP Zinc transporter	zupT	-	-	ko:K07238,ko:K11021,ko:K16267	-	-	-	-	ko00000,ko02000,ko02042	2.A.5.4.11,2.A.5.5	-	-	Zip
LZS3_k127_4572722_87	1111069.TCCBUS3UF1_6550	5.039e-25	108.0	COG1324@1|root,COG1324@2|Bacteria,1WKG6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
LZS3_k127_4572722_66	1480694.DC28_07915	4.758e-46	178.0	COG1752@1|root,COG1752@2|Bacteria,2J6JW@203691|Spirochaetes	203691|Spirochaetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
LZS3_k127_4572722_73	869210.Marky_0091	1.963e-40	160.0	COG1912@1|root,COG1912@2|Bacteria,1WIIQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
LZS3_k127_4572722_9	945713.IALB_1250	1.151e-154	503.0	COG1690@1|root,COG1690@2|Bacteria	2|Bacteria	S	RNA ligase activity	rtcB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
LZS3_k127_4572722_10	926550.CLDAP_16500	1.92e-153	492.0	COG0158@1|root,COG0158@2|Bacteria	2|Bacteria	G	fructose 1,6-bisphosphate 1-phosphatase activity	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C4836,ic_1306.c5329	FBPase
LZS3_k127_4572722_7	880073.Calab_2784	1.983e-163	530.0	COG1164@1|root,COG1164@2|Bacteria,2NQ8K@2323|unclassified Bacteria	2|Bacteria	E	Oligoendopeptidase f	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2,Peptidase_M3
LZS3_k127_4572722_74	880073.Calab_0082	2.263e-40	157.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_4572722_79	502025.Hoch_1519	2.47e-33	132.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,42UIZ@68525|delta/epsilon subdivisions,2WQ43@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
LZS3_k127_4572722_50	933262.AXAM01000020_gene27	9.292e-72	255.0	COG0491@1|root,COG0491@2|Bacteria,1R4FA@1224|Proteobacteria,42TD1@68525|delta/epsilon subdivisions,2WPPD@28221|Deltaproteobacteria,2MQ1T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_4572722_111	1379698.RBG1_1C00001G1235	1.97e-07	64.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
LZS3_k127_4572722_86	331678.Cphamn1_1714	1.518e-25	115.0	COG0811@1|root,COG0811@2|Bacteria,1FEKE@1090|Chlorobi	1090|Chlorobi	D	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
LZS3_k127_4572722_83	1123376.AUIU01000004_gene1156	4.541e-29	121.0	COG0848@1|root,COG0848@2|Bacteria,3J0T6@40117|Nitrospirae	40117|Nitrospirae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
LZS3_k127_4572722_113	1267533.KB906734_gene4206	9.471e-06	55.0	COG0810@1|root,COG0810@2|Bacteria,3Y3T5@57723|Acidobacteria,2JHKT@204432|Acidobacteriia	204432|Acidobacteriia	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2,TonB_C
LZS3_k127_4572722_54	443143.GM18_0574	2.625e-67	247.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
LZS3_k127_4572722_70	290512.Paes_0751	1.099e-41	158.0	COG2885@1|root,COG2885@2|Bacteria,1FEC5@1090|Chlorobi	1090|Chlorobi	M	PFAM OmpA MotB domain protein	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
LZS3_k127_4572722_91	1232410.KI421412_gene199	9.871e-21	101.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42T19@68525|delta/epsilon subdivisions,2WQ0M@28221|Deltaproteobacteria,43V8E@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
LZS3_k127_4572722_47	574087.Acear_0620	1.783e-73	263.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
LZS3_k127_4572722_71	1410668.JNKC01000007_gene826	1.365e-41	169.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
LZS3_k127_4572722_43	1379270.AUXF01000004_gene3060	8.092e-77	270.0	COG3367@1|root,COG3367@2|Bacteria,1ZUM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
LZS3_k127_4572722_34	1382306.JNIM01000001_gene2893	2.896e-87	299.0	COG4948@1|root,COG4948@2|Bacteria,2G8E6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing protein	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
LZS3_k127_4572722_85	1121456.ATVA01000016_gene1995	2.296e-26	113.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,2MCER@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
LZS3_k127_4572722_58	1379698.RBG1_1C00001G1815	5.371e-57	216.0	COG0477@1|root,COG2814@2|Bacteria,2NPJ1@2323|unclassified Bacteria	2|Bacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_4572722_103	1261545.MBE-HAL_2357	2.435e-12	74.0	COG0071@1|root,arCOG01832@2157|Archaea,2XYW4@28890|Euryarchaeota,23X30@183963|Halobacteria	183963|Halobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
LZS3_k127_4572722_89	1500890.JQNL01000001_gene2980	2.539e-23	115.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,1RZBM@1236|Gammaproteobacteria,1X4YD@135614|Xanthomonadales	135614|Xanthomonadales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
LZS3_k127_4572722_19	1123371.ATXH01000009_gene1104	2.005e-127	422.0	COG1109@1|root,COG1109@2|Bacteria,2GHQ7@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS3_k127_4572722_6	1242864.D187_007079	5.764e-167	549.0	COG0457@1|root,COG0457@2|Bacteria,1NTKG@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4572722_48	1322246.BN4_11957	1.818e-73	259.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,42QVG@68525|delta/epsilon subdivisions,2WNKA@28221|Deltaproteobacteria,2M9AG@213115|Desulfovibrionales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_4572722_110	929713.NIASO_16660	6.601e-08	63.0	2C537@1|root,34276@2|Bacteria,4P4UT@976|Bacteroidetes,1IYHI@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4572722_16	760568.Desku_1651	8.352e-136	449.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
LZS3_k127_4572722_2	452637.Oter_4531	8.271e-189	605.0	COG4805@1|root,COG4805@2|Bacteria,46T5D@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
LZS3_k127_4572722_41	1392490.JHZX01000001_gene628	3.665e-78	290.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,1I1YW@117743|Flavobacteriia	976|Bacteroidetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
LZS3_k127_4572722_93	880073.Calab_2081	1.949e-19	104.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_4572722_17	1121406.JAEX01000007_gene2379	9.144e-136	444.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,42NHC@68525|delta/epsilon subdivisions,2WJQJ@28221|Deltaproteobacteria,2MGAK@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
LZS3_k127_4572722_80	1121406.JAEX01000007_gene2380	3.708e-33	131.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,42WKN@68525|delta/epsilon subdivisions,2WRXH@28221|Deltaproteobacteria,2MCPQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
LZS3_k127_4572722_11	502025.Hoch_1908	3.78e-149	484.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,42NHS@68525|delta/epsilon subdivisions,2WJHI@28221|Deltaproteobacteria,2YU3U@29|Myxococcales	28221|Deltaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
LZS3_k127_4572722_90	1128421.JAGA01000002_gene1803	4.192e-23	102.0	COG2146@1|root,COG2146@2|Bacteria,2NQ87@2323|unclassified Bacteria	2|Bacteria	P	Rieske-like [2Fe-2S] domain	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
LZS3_k127_4572722_21	177437.HRM2_09150	5.698e-115	380.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2MI8E@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Protein of unknown function (DUF933)	-	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
LZS3_k127_4572722_22	1150600.ADIARSV_2104	1.52e-114	381.0	COG1092@1|root,COG1092@2|Bacteria,4NG9S@976|Bacteroidetes,1INTU@117747|Sphingobacteriia	976|Bacteroidetes	J	PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
LZS3_k127_4572722_49	68570.DC74_2304	3.925e-73	254.0	COG0778@1|root,COG0778@2|Bacteria,2GPB4@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
LZS3_k127_4572722_67	1122221.JHVI01000017_gene2093	9.957e-46	170.0	COG2905@1|root,COG2905@2|Bacteria,1WJV4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
LZS3_k127_4572722_92	1144319.PMI16_00529	1.069e-20	99.0	COG5528@1|root,COG5528@2|Bacteria,1RIIR@1224|Proteobacteria	1224|Proteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
LZS3_k127_4572722_78	448385.sce3387	1.561e-34	145.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4572722_106	1121481.AUAS01000013_gene4284	6.68e-12	76.0	2DBUB@1|root,2ZB53@2|Bacteria,4NMWS@976|Bacteroidetes,47P3Z@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4572722_29	1197477.IA57_06430	1.48e-97	332.0	COG1858@1|root,COG1858@2|Bacteria,4NE4P@976|Bacteroidetes,1HXUF@117743|Flavobacteriia	976|Bacteroidetes	C	cytochrome C peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
LZS3_k127_4572722_63	1435051.BMOU_1960	3.574e-52	193.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4D0DC@85004|Bifidobacteriales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
LZS3_k127_4572722_108	929562.Emtol_2696	2.502e-09	64.0	COG4319@1|root,COG4319@2|Bacteria,4NSA0@976|Bacteroidetes,47RMW@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
LZS3_k127_4572722_45	28072.Nos7524_0478	6.133e-76	261.0	COG1225@1|root,COG1225@2|Bacteria,1G0JC@1117|Cyanobacteria,1HJVW@1161|Nostocales	1117|Cyanobacteria	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_4572722_5	518766.Rmar_0711	9.826e-168	536.0	COG0761@1|root,COG0761@2|Bacteria,4PEGY@976|Bacteroidetes,1FJ40@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
LZS3_k127_4572722_68	1123278.KB893387_gene4337	6.315e-44	181.0	COG2755@1|root,COG3391@1|root,COG2755@2|Bacteria,COG3391@2|Bacteria,4PI0M@976|Bacteroidetes,47R8B@768503|Cytophagia	976|Bacteroidetes	E	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
LZS3_k127_4572722_102	880073.Calab_3526	1.488e-12	81.0	COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria	2|Bacteria	S	Por secretion system C-terminal sorting domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
LZS3_k127_4572722_1	314345.SPV1_12555	2.928e-233	739.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria	1224|Proteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short_C2
LZS3_k127_4572722_69	485913.Krac_8040	6.964e-42	167.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	DA1-like,GAF,Guanylate_cyc,HAMP,PAS_4,PAS_9,Response_reg,dCache_1
LZS3_k127_4572722_24	696369.KI912183_gene253	3.112e-113	374.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,260YV@186807|Peptococcaceae	186801|Clostridia	C	PFAM isocitrate isopropylmalate dehydrogenase	icd	-	1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73	ko:K00030,ko:K07246	ko00020,ko00630,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00650,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00215,R00709,R01751,R02545,R06180	RC00084,RC00105,RC00114,RC00594	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
LZS3_k127_4572722_8	511062.GU3_06675	4.693e-156	501.0	COG3007@1|root,COG3007@2|Bacteria,1MWCQ@1224|Proteobacteria,1RPPP@1236|Gammaproteobacteria,1Y3SK@135624|Aeromonadales	135624|Aeromonadales	I	Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP)	fabV	-	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
LZS3_k127_4572722_115	880073.Calab_1708	5.579e-05	57.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Fn3-like,Glyco_hydro_3_C,SLH
LZS3_k127_4572722_114	794903.OPIT5_14840	2.438e-05	58.0	COG1636@1|root,COG1636@2|Bacteria,46YPJ@74201|Verrucomicrobia,3K9XZ@414999|Opitutae	414999|Opitutae	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4572722_30	485913.Krac_1006	6.868e-97	331.0	COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.2.21	-	-	MFS_1,MFS_1_like,Sugar_tr
LZS3_k127_4572722_56	930169.B5T_04164	2.425e-62	219.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1XJR3@135619|Oceanospirillales	135619|Oceanospirillales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS3_k127_4572722_88	1201290.M902_1863	3.784e-24	109.0	COG1321@1|root,COG1321@2|Bacteria,1NPSR@1224|Proteobacteria,43B3N@68525|delta/epsilon subdivisions,2WQ9R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
LZS3_k127_4572722_97	742743.HMPREF9453_02039	9.6e-16	80.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,4H6E6@909932|Negativicutes	909932|Negativicutes	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
LZS3_k127_4572722_3	452637.Oter_0871	9.025e-179	586.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
LZS3_k127_4572722_23	246197.MXAN_0981	9.773e-114	386.0	COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria	1224|Proteobacteria	P	rieske 2Fe-2S domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
LZS3_k127_4572722_36	1121472.AQWN01000003_gene1405	6.185e-86	300.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,261AS@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
LZS3_k127_4572722_0	1408445.JHXP01000018_gene3434	0.0	1107.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1JCVR@118969|Legionellales	118969|Legionellales	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
LZS3_k127_4572722_75	243365.CV_0228	1.569e-37	154.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,2WGZN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
LZS3_k127_4572722_39	398767.Glov_2097	4.055e-82	300.0	COG0747@1|root,COG0747@2|Bacteria,1R7KU@1224|Proteobacteria	1224|Proteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
LZS3_k127_4572722_60	348780.NP_3650A	1.21e-54	207.0	COG0183@1|root,arCOG01278@2157|Archaea,2XT38@28890|Euryarchaeota,23STJ@183963|Halobacteria	183963|Halobacteria	I	COG0183 Acetyl-CoA acetyltransferase	acaB1	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
LZS3_k127_4572722_81	646529.Desaci_3334	2.004e-32	132.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,26250@186807|Peptococcaceae	186801|Clostridia	S	PFAM Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
LZS3_k127_4572722_112	1242864.D187_003545	8.487e-06	59.0	COG4412@1|root,COG4932@1|root,COG4412@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,438GF@68525|delta/epsilon subdivisions,2X3RA@28221|Deltaproteobacteria,2YWWZ@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial Ig-like domain (group 1)	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,LTD
LZS3_k127_4572722_28	880073.Calab_1105	8.461e-98	363.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713,ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.33.1	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Peptidase_S8,Pkinase,VCBS
LZS3_k127_4591098_8	517418.Ctha_2164	0.0003083	51.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,1FERA@1090|Chlorobi	1090|Chlorobi	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4591098_6	459349.CLOAM0430	9.279e-12	79.0	COG2067@1|root,COG2067@2|Bacteria,2NQZT@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4591098_0	880073.Calab_0681	2.743e-159	553.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,2NP51@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	pkn5	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	AAA_16,GAF,HAMP,HATPase_c_2,Pkinase,SpoIIE,dCache_1
LZS3_k127_4591098_5	880073.Calab_2295	1.089e-15	93.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	spoIIAA	-	-	ko:K02066,ko:K04749	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000,ko03021	3.A.1.27	-	-	APH,STAS,STAS_2
LZS3_k127_4591098_4	880073.Calab_0680	4.927e-19	104.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS3_k127_4591098_1	502025.Hoch_4669	6.843e-51	190.0	COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS3_k127_4591098_7	1207063.P24_18854	4.581e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,1QZ3F@1224|Proteobacteria,2TY48@28211|Alphaproteobacteria,2JQQM@204441|Rhodospirillales	204441|Rhodospirillales	Q	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
LZS3_k127_4591098_3	880073.Calab_0680	2.804e-32	129.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS3_k127_4591098_2	880073.Calab_0680	7.578e-33	132.0	COG1366@1|root,COG1366@2|Bacteria,2NR50@2323|unclassified Bacteria	2|Bacteria	T	Anti-sigma factor antagonist	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
LZS3_k127_4645066_11	1307759.JOMJ01000004_gene2498	1.825e-40	164.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2MG45@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_4645066_6	479434.Sthe_1132	3.826e-67	245.0	COG0297@1|root,COG0438@1|root,COG0726@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,COG0726@2|Bacteria,2G8HZ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS3_k127_4645066_13	387631.Asulf_00033	1.158e-24	117.0	COG0438@1|root,arCOG01407@2157|Archaea	2157|Archaea	M	COG0438 Glycosyltransferase	gth2	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_4645066_5	525904.Tter_2796	1.837e-87	313.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	-	2.1.1.45,2.7.4.9	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02094,R02098,R02101	RC00002,RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
LZS3_k127_4645066_8	1230476.C207_02131	1.291e-52	198.0	COG0438@1|root,COG0438@2|Bacteria,1N2J8@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_4645066_4	1211815.CBYP010000034_gene2129	8.808e-88	308.0	COG0438@1|root,COG0438@2|Bacteria,2GSQI@201174|Actinobacteria,4ES49@85013|Frankiales	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_4645066_1	237368.SCABRO_03724	1.505e-171	568.0	COG1389@1|root,COG1389@2|Bacteria,2J2A8@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,Topo-VIb_trans
LZS3_k127_4645066_0	237368.SCABRO_03725	2.298e-187	589.0	COG1697@1|root,COG1697@2|Bacteria,2J34C@203682|Planctomycetes	203682|Planctomycetes	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
LZS3_k127_4645066_16	880073.Calab_0924	2.868e-09	68.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_4645066_9	1207055.C100_14560	2.529e-45	170.0	2F2W2@1|root,33VRW@2|Bacteria,1NWGQ@1224|Proteobacteria,2USG4@28211|Alphaproteobacteria,2K96B@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
LZS3_k127_4645066_12	861299.J421_4150	6.16e-33	134.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
LZS3_k127_4645066_2	1237500.ANBA01000007_gene3030	1.941e-109	355.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
LZS3_k127_4645066_3	1210884.HG799474_gene15174	1.785e-97	325.0	COG0730@1|root,COG0730@2|Bacteria,2J37C@203682|Planctomycetes	203682|Planctomycetes	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
LZS3_k127_4645066_17	1128421.JAGA01000003_gene3022	2.506e-06	60.0	COG1306@1|root,COG1306@2|Bacteria,2NQXI@2323|unclassified Bacteria	2|Bacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
LZS3_k127_4645066_7	1144275.COCOR_07198	1.611e-62	248.0	COG2706@1|root,COG2706@2|Bacteria,1QYRS@1224|Proteobacteria	1224|Proteobacteria	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4645066_14	880073.Calab_2326	1.709e-21	112.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin-like,SLH,TSP_3
LZS3_k127_4645066_15	1068980.ARVW01000001_gene1711	3.583e-21	108.0	COG2207@1|root,COG2207@2|Bacteria,2H1NG@201174|Actinobacteria,4E2FM@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
LZS3_k127_4645066_10	1442599.JAAN01000043_gene415	1.407e-44	170.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,1X4D8@135614|Xanthomonadales	135614|Xanthomonadales	S	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
LZS3_k127_4724960_1	1192034.CAP_2899	1.029e-131	437.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42PCA@68525|delta/epsilon subdivisions,2WM39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_4724960_0	880073.Calab_3776	1.246e-146	477.0	COG0621@1|root,COG0621@2|Bacteria,2NNUN@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
LZS3_k127_4724960_2	945713.IALB_3108	4.622e-58	208.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	cccE	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
LZS3_k127_4724960_3	1274524.BSONL12_18979	1.033e-32	133.0	COG0346@1|root,COG0346@2|Bacteria,1VCGT@1239|Firmicutes,4HKDV@91061|Bacilli,1ZGXG@1386|Bacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_4724960_4	485918.Cpin_1365	5.375e-30	132.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS3_k127_4724960_5	404589.Anae109_4158	2.027e-13	79.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS3_k127_4729871_5	1122603.ATVI01000006_gene55	2.378e-163	536.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1X478@135614|Xanthomonadales	135614|Xanthomonadales	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS3_k127_4729871_33	459349.CLOAM0061	1.029e-14	87.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	wprA	-	3.1.3.6,3.1.4.16,3.2.1.99	ko:K01119,ko:K06113,ko:K12685,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Mucin_bdg,Peptidase_M60,Peptidase_S8,SLH
LZS3_k127_4729871_11	641491.DND132_0695	1.357e-103	353.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria,2MEFN@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Cytochrome b b6 domain	cbcP	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_N_2,Cytochrome_B
LZS3_k127_4729871_20	596151.DesfrDRAFT_0648	1.737e-50	187.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
LZS3_k127_4729871_2	641491.DND132_0693	4.658e-240	767.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,42QJC@68525|delta/epsilon subdivisions,2WPI2@28221|Deltaproteobacteria,2M9VY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_10,TPR_16,TPR_19,TPR_4,TPR_8
LZS3_k127_4729871_6	219305.MCAG_05245	9.403e-137	441.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4DAXK@85008|Micromonosporales	201174|Actinobacteria	EK	Cystathionine beta-synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_4729871_3	243233.MCA0317	1.155e-199	632.0	COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,1S012@1236|Gammaproteobacteria,1XDJS@135618|Methylococcales	135618|Methylococcales	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
LZS3_k127_4729871_17	1396141.BATP01000042_gene1906	3.209e-57	207.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
LZS3_k127_4729871_8	1415756.JQMY01000001_gene871	1.698e-131	430.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
LZS3_k127_4729871_26	1279009.ADICEAN_02097	4.328e-28	128.0	COG0823@1|root,COG1649@1|root,COG2931@1|root,COG3055@1|root,COG3210@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1649@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,4NPRK@976|Bacteroidetes	976|Bacteroidetes	U	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4729871_0	1380386.JIAW01000010_gene4303	0.0	1049.0	COG2224@1|root,COG2224@2|Bacteria,2I926@201174|Actinobacteria,232A9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Isocitrate lyase	aceAb	GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
LZS3_k127_4729871_28	1313421.JHBV01000013_gene3802	3.569e-26	120.0	COG2885@1|root,COG2885@2|Bacteria,4NW6U@976|Bacteroidetes	976|Bacteroidetes	M	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,OmpA
LZS3_k127_4729871_39	1313421.JHBV01000030_gene2179	7.579e-10	70.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
LZS3_k127_4729871_13	338966.Ppro_1962	1.22e-89	305.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2WKGK@28221|Deltaproteobacteria,43U0E@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
LZS3_k127_4729871_49	313628.LNTAR_09219	0.0002255	55.0	COG1636@1|root,COG1636@2|Bacteria	2|Bacteria	C	queuosine biosynthetic process	queH	-	1.17.99.6,3.1.26.4	ko:K03470,ko:K09765	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03032	-	-	-	DUF208
LZS3_k127_4729871_38	880073.Calab_2549	9.997e-11	76.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_4729871_24	1117943.SFHH103_01812	2.574e-37	147.0	COG3547@1|root,COG3547@2|Bacteria,1Q4TE@1224|Proteobacteria,2TT7C@28211|Alphaproteobacteria,4BB4U@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
LZS3_k127_4729871_18	290397.Adeh_2253	1.656e-52	190.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales	28221|Deltaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
LZS3_k127_4729871_14	1047013.AQSP01000103_gene1152	1.264e-66	245.0	COG1680@1|root,COG1680@2|Bacteria,2NRG7@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_4729871_34	1278073.MYSTI_02208	1.625e-14	85.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,2YYW2@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
LZS3_k127_4729871_36	215803.DB30_1319	3.096e-13	76.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,2YW1G@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
LZS3_k127_4729871_46	1168065.DOK_14604	5.823e-05	51.0	COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,1S6FK@1236|Gammaproteobacteria,1JAY5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
LZS3_k127_4729871_23	1201288.M900_0340	5.248e-39	153.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2MU21@213481|Bdellovibrionales,2WQK7@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS3_k127_4729871_21	1144275.COCOR_01946	2.121e-50	208.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
LZS3_k127_4729871_40	198467.NP92_11720	3.856e-08	64.0	COG0860@1|root,COG3103@1|root,COG3807@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG3807@2|Bacteria,1UYPW@1239|Firmicutes,4HBVT@91061|Bacilli,21W93@150247|Anoxybacillus	91061|Bacilli	MT	Ami_3	lytH	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
LZS3_k127_4729871_32	518766.Rmar_0721	8.598e-15	88.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4729871_37	521011.Mpal_2074	3.258e-13	83.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea	2157|Archaea	P	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Lipase_GDSL_2,NHL,NosD,PKD,Peptidase_C1,Peptidase_S8,Tail_P2_I
LZS3_k127_4729871_35	28229.ND2E_3090	1.315e-13	83.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria,1RQKS@1236|Gammaproteobacteria,2Q61I@267889|Colwelliaceae	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
LZS3_k127_4729871_44	493475.GARC_2208	1.365e-05	53.0	2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,468BH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
LZS3_k127_4729871_29	638303.Thal_0395	2.14e-22	104.0	COG0526@1|root,COG0526@2|Bacteria,2G483@200783|Aquificae	200783|Aquificae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_4729871_22	396588.Tgr7_0551	2.263e-48	196.0	COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,1RNKG@1236|Gammaproteobacteria,1X1NS@135613|Chromatiales	135613|Chromatiales	U	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS3_k127_4729871_48	243231.GSU0810	8.388e-05	55.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2WVVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA
LZS3_k127_4729871_41	886293.Sinac_6318	1.058e-06	59.0	COG4637@1|root,COG5492@1|root,COG4637@2|Bacteria,COG5492@2|Bacteria,2IXP9@203682|Planctomycetes	2|Bacteria	N	Protein of unknown function (DUF1549)	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	AAA_15,AAA_21,Big_2,PSCyt2,PSD1
LZS3_k127_4729871_19	234267.Acid_6150	5.472e-52	197.0	COG1477@1|root,COG1477@2|Bacteria,3Y4B0@57723|Acidobacteria	57723|Acidobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
LZS3_k127_4729871_27	929556.Solca_1445	1.776e-27	120.0	2ATWF@1|root,31JFP@2|Bacteria,4NQPB@976|Bacteroidetes,1ITBA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4729871_30	459349.CLOAM0631	1.939e-18	102.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
LZS3_k127_4729871_45	192952.MM_1144	3.636e-05	58.0	COG5563@1|root,arCOG03499@1|root,arCOG03499@2157|Archaea,arCOG03501@2157|Archaea	2157|Archaea	S	Disaggregatase related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Disaggr_assoc,Disaggr_repeat,PKD
LZS3_k127_4729871_43	1120998.AUFC01000002_gene2638	5.297e-06	61.0	COG3210@1|root,COG4677@1|root,COG3210@2|Bacteria,COG4677@2|Bacteria,1TR9M@1239|Firmicutes,24BEI@186801|Clostridia	186801|Clostridia	U	S-layer domain-containing protein	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Flg_new,SLH
LZS3_k127_4729871_47	717606.PaecuDRAFT_1199	8.301e-05	57.0	COG3468@1|root,COG3468@2|Bacteria,1UJR4@1239|Firmicutes,4ITDS@91061|Bacilli,26UFP@186822|Paenibacillaceae	91061|Bacilli	MU	cell surface receptor IPT TIG domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
LZS3_k127_4729871_31	710111.FraQA3DRAFT_2836	2.5e-15	91.0	COG1073@1|root,COG1520@1|root,COG1073@2|Bacteria,COG1520@2|Bacteria,2IJK1@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050
LZS3_k127_4729871_10	335543.Sfum_1766	4.87e-122	405.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS3_k127_4729871_42	1121373.KB903664_gene2660	2.719e-06	61.0	2C7HJ@1|root,31BFZ@2|Bacteria,4NRGQ@976|Bacteroidetes,47WSM@768503|Cytophagia	976|Bacteroidetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
LZS3_k127_4729871_16	926560.KE387023_gene2884	2.455e-62	220.0	COG2318@1|root,COG2318@2|Bacteria,1WMM8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS3_k127_4729871_4	234267.Acid_5749	2.991e-172	572.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
LZS3_k127_4729871_9	314230.DSM3645_22174	3.038e-126	415.0	COG2081@1|root,COG2081@2|Bacteria,2IWW4@203682|Planctomycetes	203682|Planctomycetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
LZS3_k127_4729871_15	1144275.COCOR_01192	5.921e-63	226.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,42SKB@68525|delta/epsilon subdivisions,2WQ2K@28221|Deltaproteobacteria,2YV8W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
LZS3_k127_4729871_7	335543.Sfum_3450	9.568e-134	439.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2MQ4E@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
LZS3_k127_4729871_1	583355.Caka_1066	4.456e-293	912.0	COG0365@1|root,COG0365@2|Bacteria,46SBX@74201|Verrucomicrobia,3K77V@414999|Opitutae	414999|Opitutae	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
LZS3_k127_4729871_12	909663.KI867150_gene2214	1.971e-94	320.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MRB2@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
LZS3_k127_4729871_25	1121015.N789_09315	2.015e-29	124.0	COG4319@1|root,COG4319@2|Bacteria,1PZUH@1224|Proteobacteria,1SUHF@1236|Gammaproteobacteria,1XBQN@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
LZS3_k127_4734151_6	1499967.BAYZ01000036_gene2418	1.779e-237	741.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_4734151_15	1499967.BAYZ01000036_gene2419	5.061e-164	522.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
LZS3_k127_4734151_121	1047013.AQSP01000120_gene963	2.125e-06	55.0	2AB38@1|root,310H2@2|Bacteria,2NRWF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4734151_43	1125863.JAFN01000001_gene413	4.755e-71	246.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42URP@68525|delta/epsilon subdivisions,2WQFZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
LZS3_k127_4734151_90	316067.Geob_3254	4.73e-26	117.0	2E80N@1|root,332EV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4734151_118	379066.GAU_0151	3.043e-07	59.0	28YEJ@1|root,2ZK8Z@2|Bacteria,1ZU80@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4734151_128	1121930.AQXG01000003_gene2539	0.0001802	53.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,Laminin_G_3,SLH,TonB_dep_Rec
LZS3_k127_4734151_99	323850.Shew_0856	6.921e-19	101.0	COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,1SCJF@1236|Gammaproteobacteria,2QCNK@267890|Shewanellaceae	1236|Gammaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
LZS3_k127_4734151_25	857087.Metme_0552	1.267e-121	394.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,1RPKU@1236|Gammaproteobacteria,1XEU8@135618|Methylococcales	135618|Methylococcales	G	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
LZS3_k127_4734151_5	1565129.JSFF01000003_gene2069	2.179e-275	865.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMXI@1236|Gammaproteobacteria,2Q9ZC@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase M3A and M3B, thimet oligopeptidase F	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
LZS3_k127_4734151_67	1121015.N789_00635	2.385e-44	167.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,1SGRZ@1236|Gammaproteobacteria,1X6RX@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
LZS3_k127_4734151_84	661478.OP10G_2545	5.055e-32	139.0	2EBC4@1|root,335CV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_53
LZS3_k127_4734151_44	930171.Asphe3_09570	5.026e-68	239.0	2ANI9@1|root,31DH5@2|Bacteria,2GJE8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4734151_78	1121468.AUBR01000001_gene470	2.806e-34	135.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,42H4U@68295|Thermoanaerobacterales	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
LZS3_k127_4734151_28	945713.IALB_0461	6.752e-114	393.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS3_k127_4734151_1	761193.Runsl_1910	0.0	1413.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,4PM8I@976|Bacteroidetes,47N7Y@768503|Cytophagia	976|Bacteroidetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
LZS3_k127_4734151_92	1297742.A176_00934	4.825e-25	106.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42V9P@68525|delta/epsilon subdivisions,2X5QW@28221|Deltaproteobacteria,2Z1ZE@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
LZS3_k127_4734151_66	1191523.MROS_0247	8.832e-45	166.0	COG3304@1|root,COG3304@2|Bacteria	2|Bacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
LZS3_k127_4734151_13	379066.GAU_3744	6.81e-185	588.0	COG0513@1|root,COG0513@2|Bacteria,1ZT7G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DEAD-like helicases superfamily	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
LZS3_k127_4734151_114	1121015.N789_10945	1.642e-08	64.0	COG0222@1|root,COG0222@2|Bacteria,1Q4UM@1224|Proteobacteria,1SVTC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L12
LZS3_k127_4734151_62	1184267.A11Q_1310	3.177e-52	194.0	COG0500@1|root,COG2226@2|Bacteria,1R9JW@1224|Proteobacteria,42M76@68525|delta/epsilon subdivisions,2MTER@213481|Bdellovibrionales,2WK4P@28221|Deltaproteobacteria	213481|Bdellovibrionales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
LZS3_k127_4734151_94	1122222.AXWR01000002_gene2204	1.583e-23	107.0	COG0454@1|root,COG0456@2|Bacteria,1WK4D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	FR47-like protein	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
LZS3_k127_4734151_64	945713.IALB_0422	1.034e-49	188.0	2DM5T@1|root,31U0Y@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
LZS3_k127_4734151_105	506534.Rhein_0329	1.298e-14	83.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
LZS3_k127_4734151_41	485913.Krac_5030	1.006e-73	258.0	COG2514@1|root,COG2514@2|Bacteria,2G6MQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
LZS3_k127_4734151_7	204669.Acid345_2328	1.018e-232	739.0	COG1770@1|root,COG1770@2|Bacteria,3Y3PK@57723|Acidobacteria,2JIWT@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS3_k127_4734151_49	644548.SCNU_10409	1.741e-61	221.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4GC77@85026|Gordoniaceae	201174|Actinobacteria	G	Inositol monophosphatase family	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
LZS3_k127_4734151_96	1265313.HRUBRA_00686	5.977e-22	103.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,1JBFQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
LZS3_k127_4734151_75	631362.Thi970DRAFT_00127	1.435e-38	148.0	COG2076@1|root,COG2076@2|Bacteria,1MZ6P@1224|Proteobacteria,1S8TD@1236|Gammaproteobacteria,1WYQ8@135613|Chromatiales	135613|Chromatiales	U	PFAM small multidrug resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
LZS3_k127_4734151_3	1499967.BAYZ01000033_gene1128	9.486e-297	927.0	COG1217@1|root,COG1217@2|Bacteria,2NNY7@2323|unclassified Bacteria	2|Bacteria	T	Elongation factor G C-terminus	typA	GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
LZS3_k127_4734151_58	925409.KI911562_gene1445	4.216e-54	202.0	COG2520@1|root,COG2520@2|Bacteria,4NNG5@976|Bacteroidetes	976|Bacteroidetes	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
LZS3_k127_4734151_42	555779.Dthio_PD3659	1.301e-73	256.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42MBJ@68525|delta/epsilon subdivisions,2WNWX@28221|Deltaproteobacteria,2MBDA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
LZS3_k127_4734151_87	886293.Sinac_1589	3.202e-29	124.0	2E3Q3@1|root,32YN2@2|Bacteria,2J0W4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4734151_35	404589.Anae109_1432	1.692e-92	320.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
LZS3_k127_4734151_85	270374.MELB17_13022	8.042e-31	139.0	COG0694@1|root,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria	1224|Proteobacteria	C	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins	nfuA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0010467,GO:0015976,GO:0016043,GO:0016226,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564	-	ko:K07400	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn,NifU
LZS3_k127_4734151_23	1382306.JNIM01000001_gene1917	5.941e-122	413.0	COG1032@1|root,COG1032@2|Bacteria,2G7MA@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
LZS3_k127_4734151_46	644966.Tmar_1774	3.879e-65	253.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WCUH@538999|Clostridiales incertae sedis	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
LZS3_k127_4734151_60	748280.NH8B_1339	6.091e-53	193.0	COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2VTFR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
LZS3_k127_4734151_20	518766.Rmar_0086	1.785e-143	462.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,1FJJ9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
LZS3_k127_4734151_4	204669.Acid345_3507	2.16e-291	918.0	COG0567@1|root,COG0567@2|Bacteria,3Y3EF@57723|Acidobacteria,2JICX@204432|Acidobacteriia	204432|Acidobacteriia	C	2-oxoglutarate dehydrogenase, E1	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoGdeHyase_C,Transket_pyr
LZS3_k127_4734151_71	335283.Neut_1444	2.091e-41	172.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria,374K3@32003|Nitrosomonadales	28216|Betaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
LZS3_k127_4734151_124	509191.AEDB02000108_gene1649	2.755e-05	55.0	COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,249UE@186801|Clostridia,3WJGR@541000|Ruminococcaceae	186801|Clostridia	M	SH3 type 3 domain protein	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	NLPC_P60,SH3_3
LZS3_k127_4734151_77	1487923.DP73_18370	1.159e-34	140.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,2630J@186807|Peptococcaceae	186801|Clostridia	S	PFAM BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
LZS3_k127_4734151_80	1192034.CAP_8159	1.415e-32	141.0	COG1196@1|root,COG1196@2|Bacteria,1R3XQ@1224|Proteobacteria,42YF5@68525|delta/epsilon subdivisions,2WUDV@28221|Deltaproteobacteria,2YUE5@29|Myxococcales	28221|Deltaproteobacteria	D	HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid
LZS3_k127_4734151_115	1122915.AUGY01000013_gene2822	4.023e-08	61.0	COG4911@1|root,COG4911@2|Bacteria,1VEVZ@1239|Firmicutes,4HNX1@91061|Bacilli,26Z6Z@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
LZS3_k127_4734151_11	945713.IALB_1465	3.101e-204	656.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
LZS3_k127_4734151_74	502025.Hoch_4515	3.018e-39	152.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2WRSP@28221|Deltaproteobacteria,2Z31G@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
LZS3_k127_4734151_16	1379698.RBG1_1C00001G0684	7.405e-162	528.0	COG0277@1|root,COG0277@2|Bacteria,2NP1E@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104,ko:K18930	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
LZS3_k127_4734151_51	1121957.ATVL01000014_gene1459	3.48e-59	227.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4734151_101	880073.Calab_3296	1.436e-16	94.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
LZS3_k127_4734151_79	1408254.T458_06295	2.692e-33	151.0	COG1404@1|root,COG1404@2|Bacteria,1UGHG@1239|Firmicutes,4HC8T@91061|Bacilli,26TIJ@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,SLH
LZS3_k127_4734151_98	459349.CLOAM0582	3.393e-21	111.0	COG1572@1|root,COG3391@1|root,COG4412@1|root,COG4733@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	3.4.21.96	ko:K01361,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	F5_F8_type_C,Glucosaminidase,SLH
LZS3_k127_4734151_82	644966.Tmar_1540	1.917e-32	138.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia	186801|Clostridia	L	COG3547, transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
LZS3_k127_4734151_119	1121017.AUFG01000036_gene646	5.898e-07	53.0	COG3547@1|root,COG3547@2|Bacteria,2IDDB@201174|Actinobacteria,4FEYP@85021|Intrasporangiaceae	201174|Actinobacteria	L	COG3547 Transposase and inactivated derivatives	tnp3512a	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
LZS3_k127_4734151_56	234267.Acid_3295	2.582e-54	210.0	COG2373@1|root,COG3386@1|root,COG2373@2|Bacteria,COG3386@2|Bacteria,3Y3S3@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_3_5,NHL
LZS3_k127_4734151_47	335541.Swol_1378	3.699e-64	235.0	COG3386@1|root,COG3386@2|Bacteria,1UHWM@1239|Firmicutes	1239|Firmicutes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4734151_112	1127134.NOCYR_0930	2.738e-10	72.0	COG3794@1|root,COG3794@2|Bacteria,2GSBM@201174|Actinobacteria,4G2JT@85025|Nocardiaceae	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
LZS3_k127_4734151_22	1380394.JADL01000008_gene3732	3.752e-129	422.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,2JPAI@204441|Rhodospirillales	204441|Rhodospirillales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
LZS3_k127_4734151_123	591019.Shell_0451	1.136e-05	56.0	COG1520@1|root,arCOG02492@2157|Archaea	2157|Archaea	M	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Big_5,CHB_HEX_C_1,PKD,PQQ_2,PQQ_3
LZS3_k127_4734151_129	207559.Dde_2156	0.0005335	50.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria,2MDBG@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS3_k127_4734151_108	561180.BIFGAL_02973	6.731e-12	76.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,4CZ36@85004|Bifidobacteriales	201174|Actinobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
LZS3_k127_4734151_111	1191523.MROS_1634	2.198e-10	74.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_1634|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4734151_107	696747.NIES39_B00440	7.389e-13	80.0	COG0457@1|root,COG0457@2|Bacteria,1GQEI@1117|Cyanobacteria,1HI2Q@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_8
LZS3_k127_4734151_32	1379698.RBG1_1C00001G1759	8.154e-106	349.0	COG0330@1|root,COG0330@2|Bacteria,2NNUC@2323|unclassified Bacteria	2|Bacteria	O	prohibitin homologues	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS3_k127_4734151_26	269799.Gmet_0813	5.635e-117	393.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,43SBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
LZS3_k127_4734151_63	502025.Hoch_5432	8.902e-52	190.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,42U6P@68525|delta/epsilon subdivisions,2WQ00@28221|Deltaproteobacteria,2YVG1@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
LZS3_k127_4734151_38	945713.IALB_0376	3.566e-82	293.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
LZS3_k127_4734151_89	1340493.JNIF01000003_gene4501	3.713e-28	116.0	COG0776@1|root,COG0776@2|Bacteria,3Y4U2@57723|Acidobacteria	57723|Acidobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS3_k127_4734151_68	596152.DesU5LDRAFT_0330	2.971e-44	181.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YZ2@68525|delta/epsilon subdivisions,2WTQ1@28221|Deltaproteobacteria,2MHCF@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,sCache_3_2
LZS3_k127_4734151_21	1232410.KI421428_gene1054	4.518e-133	438.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_4734151_116	1249634.D781_3232	5.367e-08	63.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNG1@1236|Gammaproteobacteria,400IZ@613|Serratia	1236|Gammaproteobacteria	T	Histidine kinase	cpxA_1	-	2.7.13.3	ko:K02484,ko:K07640	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HK_sensor,HisKA
LZS3_k127_4734151_120	589865.DaAHT2_1192	1.715e-06	58.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKG2@28221|Deltaproteobacteria,2MJ32@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	flbD	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_4734151_33	880073.Calab_3385	1.713e-103	353.0	COG2204@1|root,COG2204@2|Bacteria,2NQDH@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	fhlA	-	-	ko:K03413,ko:K13589	ko02020,ko02030,ko04112,map02020,map02030,map04112	M00506,M00512	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_4734151_59	945713.IALB_2930	1.124e-53	202.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4734151_36	880073.Calab_3649	8.76e-87	312.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2NP1D@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	CP_0155	-	-	ko:K08307,ko:K12204	-	-	-	-	ko00000,ko01000,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1	-	-	LysM,SLT,T4SS_TraI
LZS3_k127_4734151_76	204669.Acid345_4523	7.185e-37	156.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,3Y6D3@57723|Acidobacteria,2JKGW@204432|Acidobacteriia	2|Bacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,PAS_4,SpoIIE
LZS3_k127_4734151_113	589865.DaAHT2_1067	1.459e-08	67.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2MI3T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
LZS3_k127_4734151_54	349161.Dred_2363	3.608e-56	203.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,261MS@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
LZS3_k127_4734151_31	479434.Sthe_1292	7.633e-108	361.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia	189775|Thermomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
LZS3_k127_4734151_19	1122137.AQXF01000001_gene3384	1.694e-146	484.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
LZS3_k127_4734151_12	1487953.JMKF01000082_gene4268	1.168e-189	604.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1G06N@1117|Cyanobacteria,1H7R0@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
LZS3_k127_4734151_88	243231.GSU1484	1.136e-28	134.0	COG0457@1|root,COG0741@1|root,COG1729@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,COG1729@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,43U8J@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM Lytic transglycosylase catalytic	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
LZS3_k127_4734151_86	1379698.RBG1_1C00001G0464	7.207e-30	126.0	COG0170@1|root,COG0170@2|Bacteria,2NQ5M@2323|unclassified Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	sec59	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
LZS3_k127_4734151_104	1230476.C207_05156	5.938e-15	85.0	COG0457@1|root,COG0859@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS3_k127_4734151_109	65393.PCC7424_1987	1.013e-11	74.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,1GITV@1117|Cyanobacteria,3KK84@43988|Cyanothece	1117|Cyanobacteria	O	heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
LZS3_k127_4734151_81	452637.Oter_2189	1.793e-32	145.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia,3K9Y4@414999|Opitutae	2|Bacteria	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
LZS3_k127_4734151_2	1379698.RBG1_1C00001G1656	0.0	1092.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
LZS3_k127_4734151_110	880073.Calab_0883	1.376e-10	68.0	COG2922@1|root,COG2922@2|Bacteria	2|Bacteria	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
LZS3_k127_4734151_8	1313304.CALK_0119	9.645e-232	739.0	COG0550@1|root,COG0550@2|Bacteria	2|Bacteria	L	DNA topoisomerase type I activity	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
LZS3_k127_4734151_24	717605.Theco_2112	6.307e-122	407.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli,26QW5@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
LZS3_k127_4734151_52	562970.Btus_1487	2.411e-58	214.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HARA@91061|Bacilli,2789H@186823|Alicyclobacillaceae	91061|Bacilli	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS3_k127_4734151_97	1379698.RBG1_1C00001G1337	2.074e-21	107.0	COG2372@1|root,COG2372@2|Bacteria,2NQ3Q@2323|unclassified Bacteria	2|Bacteria	S	Bacterial Ig-like domain	-	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	Big_5,DUF4082,SLH
LZS3_k127_4734151_53	1396141.BATP01000007_gene5534	2.395e-57	212.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,2ITVJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
LZS3_k127_4734151_17	1379698.RBG1_1C00001G1445	7.545e-156	526.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NQSG@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40,Peptidase_MA_2
LZS3_k127_4734151_14	316067.Geob_2401	1.446e-178	577.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
LZS3_k127_4734151_117	1379698.RBG1_1C00001G1753	2.369e-07	57.0	COG0268@1|root,COG0268@2|Bacteria,2NQ42@2323|unclassified Bacteria	2|Bacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
LZS3_k127_4734151_39	404589.Anae109_2117	3.66e-81	280.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2YWUR@29|Myxococcales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
LZS3_k127_4734151_29	926561.KB900623_gene986	1.598e-111	370.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WADX@53433|Halanaerobiales	186801|Clostridia	J	PFAM tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
LZS3_k127_4734151_73	316067.Geob_3015	2.002e-40	166.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
LZS3_k127_4734151_72	945713.IALB_1558	1.737e-40	162.0	COG1386@1|root,COG1386@2|Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
LZS3_k127_4734151_61	1120954.ATXE01000002_gene687	2.938e-52	195.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4DNT7@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
LZS3_k127_4734151_40	448385.sce8915	8.679e-79	276.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2YUC9@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_4734151_70	936589.HMPREF1521_0211	1.35e-42	179.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4H4MX@909932|Negativicutes	909932|Negativicutes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
LZS3_k127_4734151_91	1121430.JMLG01000010_gene195	1.488e-25	124.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,261WZ@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
LZS3_k127_4734151_9	1379698.RBG1_1C00001G1225	3.718e-213	678.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010	1.17.7.4,2.7.11.1	ko:K02945,ko:K03527,ko:K12132	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko01001,ko03011	-	-	-	S1
LZS3_k127_4734151_93	644282.Deba_1300	4.414e-24	116.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,42UW4@68525|delta/epsilon subdivisions,2WR5T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	-	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2,TPR_7,TPR_8
LZS3_k127_4734151_122	1280952.HJA_12304	1.069e-05	57.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,2TUER@28211|Alphaproteobacteria,43Y9F@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
LZS3_k127_4734151_10	269799.Gmet_1424	1.352e-208	681.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
LZS3_k127_4734151_125	1242864.D187_002499	5.014e-05	57.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QV0D@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,MEDS,PAS_4,RsbRD_N
LZS3_k127_4734151_27	1379698.RBG1_1C00001G1139	5.493e-114	389.0	COG0323@1|root,COG0323@2|Bacteria,2NNP7@2323|unclassified Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
LZS3_k127_4734151_57	96561.Dole_1764	3.396e-54	207.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2MIV4@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
LZS3_k127_4734151_37	429009.Adeg_1225	4.386e-84	295.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,42EX0@68295|Thermoanaerobacterales	186801|Clostridia	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
LZS3_k127_4734151_30	264732.Moth_1322	1.335e-109	372.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,42F2X@68295|Thermoanaerobacterales	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
LZS3_k127_4734151_83	880073.Calab_3206	3.459e-32	136.0	COG0344@1|root,COG0344@2|Bacteria,2NPME@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
LZS3_k127_4734151_34	477974.Daud_1168	1.328e-99	345.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,260KV@186807|Peptococcaceae	186801|Clostridia	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
LZS3_k127_4734151_95	1379698.RBG1_1C00001G1177	2.562e-23	113.0	COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	ko:K19591,ko:K22491	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR_1
LZS3_k127_4734151_0	1384056.N787_00740	0.0	1601.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,1X36Z@135614|Xanthomonadales	135614|Xanthomonadales	E	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
LZS3_k127_4734151_100	497964.CfE428DRAFT_0946	4.902e-17	96.0	COG1560@1|root,COG1560@2|Bacteria,46WBV@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
LZS3_k127_4734151_65	1379698.RBG1_1C00001G1176	2.718e-49	186.0	COG1216@1|root,COG1216@2|Bacteria,2NS4X@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase family 2	XK27_08075	-	-	-	-	-	-	-	-	-	-	-	DUF2062,Glycos_transf_2,GtrA,Lip_A_acyltrans
LZS3_k127_4734151_45	671143.DAMO_1380	1.77e-65	241.0	COG0496@1|root,COG0496@2|Bacteria,2NPCG@2323|unclassified Bacteria	2|Bacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	iSFxv_1172.SFxv_3035	SurE
LZS3_k127_4734151_55	667014.Thein_1148	5.909e-56	205.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
LZS3_k127_4734151_69	269797.Mbar_A1583	1.27e-43	166.0	COG2426@1|root,arCOG01330@2157|Archaea,2XZ2Y@28890|Euryarchaeota,2NAQX@224756|Methanomicrobia	224756|Methanomicrobia	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
LZS3_k127_4734151_48	264732.Moth_0624	9.648e-62	224.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,42FCG@68295|Thermoanaerobacterales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_4734151_50	643648.Slip_0898	7.242e-60	214.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
LZS3_k127_4734151_18	314230.DSM3645_10052	1.082e-150	494.0	COG0457@1|root,COG0457@2|Bacteria,2IXTF@203682|Planctomycetes	203682|Planctomycetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_4803695_2	316067.Geob_1294	1.815e-154	504.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
LZS3_k127_4803695_0	926569.ANT_16170	3.01e-188	595.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
LZS3_k127_4803695_3	944480.ATUV01000001_gene1066	1.071e-145	471.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2M6KN@213113|Desulfurellales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
LZS3_k127_4803695_6	517418.Ctha_2572	3.846e-96	332.0	COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
LZS3_k127_4803695_9	1121430.JMLG01000009_gene429	1.028e-66	256.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,25ZZA@186807|Peptococcaceae	186801|Clostridia	G	Sugar isomerase (SIS)	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
LZS3_k127_4803695_1	273068.TTE2334	1.85e-162	531.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
LZS3_k127_4803695_17	522772.Dacet_1318	3.132e-10	71.0	COG1925@1|root,COG1925@2|Bacteria,2GG2N@200930|Deferribacteres	200930|Deferribacteres	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
LZS3_k127_4803695_14	290397.Adeh_0151	1.396e-19	102.0	COG3716@1|root,COG3716@2|Bacteria,1P02J@1224|Proteobacteria,42RPH@68525|delta/epsilon subdivisions,2WNQI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system mannose fructose sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
LZS3_k127_4803695_19	519441.Smon_0152	4.458e-06	57.0	COG3715@1|root,COG3715@2|Bacteria,379TZ@32066|Fusobacteria	32066|Fusobacteria	G	PFAM phosphotransferase system PTS sorbose- specific IIC subunit	-	-	-	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	M00277,M00287	R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1.4,4.A.6.1.5	-	-	EII-Sor
LZS3_k127_4803695_12	1379698.RBG1_1C00001G0555	6.371e-34	140.0	COG3444@1|root,COG3444@2|Bacteria,2NQ0P@2323|unclassified Bacteria	2|Bacteria	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794,ko:K19507	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276,M00764	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.19	-	-	PTSIIB_sorb
LZS3_k127_4803695_18	1196322.A370_00442	7.258e-10	65.0	COG2893@1|root,COG2893@2|Bacteria,1VHWY@1239|Firmicutes,25C6D@186801|Clostridia,36WQB@31979|Clostridiaceae	186801|Clostridia	G	PTS system, mannose fructose sorbose family, IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
LZS3_k127_4803695_7	1379698.RBG1_1C00001G0553	8.619e-92	312.0	COG1493@1|root,COG1493@2|Bacteria,2NP5B@2323|unclassified Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
LZS3_k127_4803695_15	283942.IL0395	2.024e-19	92.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,2QG9C@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing	yhbH	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
LZS3_k127_4803695_4	485916.Dtox_3938	1.22e-106	362.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,2480F@186801|Clostridia,260B1@186807|Peptococcaceae	186801|Clostridia	K	TIGRFAM RNA polymerase sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
LZS3_k127_4803695_5	1379698.RBG1_1C00001G0549	2.592e-99	330.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
LZS3_k127_4803695_16	1379698.RBG1_1C00001G0548	1.703e-15	84.0	COG3117@1|root,COG3117@2|Bacteria,2NQ8Q@2323|unclassified Bacteria	2|Bacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K09774,ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
LZS3_k127_4803695_11	1382359.JIAL01000001_gene375	5.538e-43	170.0	COG1560@1|root,COG1560@2|Bacteria,3Y2RW@57723|Acidobacteria,2JIMS@204432|Acidobacteriia	204432|Acidobacteriia	M	lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
LZS3_k127_4803695_10	936455.KI421499_gene2518	9.19e-60	226.0	COG3637@1|root,COG3637@2|Bacteria,1R3Z1@1224|Proteobacteria,2U1SQ@28211|Alphaproteobacteria,3JXB7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
LZS3_k127_4803695_8	1218074.BAXZ01000015_gene3189	1.76e-86	297.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,1K0GY@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
LZS3_k127_4803695_13	1121904.ARBP01000086_gene1909	5.604e-29	122.0	29XXX@1|root,30JQG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972990_17	706587.Desti_2240	7.621e-73	261.0	COG2755@1|root,COG2755@2|Bacteria,1NF6E@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS3_k127_4972990_24	1121920.AUAU01000030_gene2713	8.693e-40	152.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972990_40	1519464.HY22_13125	1.98e-12	81.0	COG0737@1|root,COG1520@1|root,COG0737@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
LZS3_k127_4972990_33	926550.CLDAP_02020	3.196e-17	97.0	COG1520@1|root,COG1520@2|Bacteria,2G93W@200795|Chloroflexi	200795|Chloroflexi	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
LZS3_k127_4972990_39	1121930.AQXG01000031_gene1647	3.541e-13	83.0	COG1319@1|root,COG1520@1|root,COG2911@1|root,COG3291@1|root,COG1319@2|Bacteria,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.1.3.1	ko:K01113,ko:K20274	ko00790,ko01100,ko02020,ko02024,map00790,map01100,map02020,map02024	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	FAD_binding_5
LZS3_k127_4972990_30	1120936.KB907215_gene3950	2.745e-23	117.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
LZS3_k127_4972990_15	1242864.D187_002017	2.132e-75	262.0	COG1028@1|root,COG1028@2|Bacteria,1MW4W@1224|Proteobacteria,43DGY@68525|delta/epsilon subdivisions,2X8NT@28221|Deltaproteobacteria,2YUWT@29|Myxococcales	28221|Deltaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
LZS3_k127_4972990_43	204669.Acid345_0673	4.126e-06	54.0	2C5W2@1|root,33IGR@2|Bacteria,3Y8EW@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972990_16	582515.KR51_00002240	9.923e-75	260.0	COG0500@1|root,COG2226@2|Bacteria,1G1WF@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
LZS3_k127_4972990_25	450851.PHZ_c2202	2.63e-38	157.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_4972990_20	861299.J421_6231	2.702e-52	200.0	COG0491@1|root,COG0491@2|Bacteria,1ZU73@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_4972990_46	765698.Mesci_0089	0.00026	50.0	COG5612@1|root,COG5612@2|Bacteria,1N8FF@1224|Proteobacteria,2UHVP@28211|Alphaproteobacteria,43QJ9@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
LZS3_k127_4972990_29	1122130.AUHN01000006_gene1827	7.43e-25	113.0	COG1595@1|root,COG1595@2|Bacteria,2GK4C@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigE	GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_4972990_27	42256.RradSPS_3078	1.002e-27	115.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
LZS3_k127_4972990_35	1174684.EBMC1_09599	1.016e-13	75.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2UFC1@28211|Alphaproteobacteria,2K66Y@204457|Sphingomonadales	204457|Sphingomonadales	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
LZS3_k127_4972990_1	926561.KB900618_gene312	3.604e-199	646.0	COG1033@1|root,COG1033@2|Bacteria	2|Bacteria	S	growth of symbiont in host cell	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	LolA_like,MMPL
LZS3_k127_4972990_19	1125863.JAFN01000001_gene70	9.127e-64	238.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42MX6@68525|delta/epsilon subdivisions,2WMMJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
LZS3_k127_4972990_12	589865.DaAHT2_2231	7.626e-83	293.0	COG4773@1|root,COG4773@2|Bacteria,1QCTH@1224|Proteobacteria,42PPC@68525|delta/epsilon subdivisions,2WIS8@28221|Deltaproteobacteria,2MMRJ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972990_6	1333998.M2A_2344	2.16e-139	455.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator Superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
LZS3_k127_4972990_21	1121920.AUAU01000006_gene301	7.128e-51	186.0	2BYAB@1|root,32R2Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972990_36	1379698.RBG1_1C00001G1784	1.162e-13	82.0	COG3391@1|root,COG3391@2|Bacteria,2NQ4G@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,DUF5128,NHL
LZS3_k127_4972990_38	667014.Thein_1798	2.262e-13	81.0	28WYN@1|root,2ZIXP@2|Bacteria,2GIB8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS3_k127_4972990_34	635013.TherJR_2221	3.243e-14	85.0	COG4409@1|root,COG4733@1|root,COG4409@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,CBM_35,DUF1080,F5_F8_type_C,PKD
LZS3_k127_4972990_37	243231.GSU2498	2.144e-13	78.0	COG4380@1|root,COG4380@2|Bacteria,1NJYS@1224|Proteobacteria,42X1E@68525|delta/epsilon subdivisions,2WTEE@28221|Deltaproteobacteria,43VPV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative bacterial lipoprotein (DUF799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF799
LZS3_k127_4972990_42	443152.MDG893_16467	1.143e-06	58.0	COG5616@1|root,COG5616@2|Bacteria,1N092@1224|Proteobacteria,1SC9K@1236|Gammaproteobacteria,46C2Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	cAMP biosynthetic process	-	-	-	ko:K21008	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	-
LZS3_k127_4972990_3	1121920.AUAU01000024_gene2388	2.757e-165	558.0	COG3005@1|root,COG3043@1|root,COG3005@2|Bacteria,COG3043@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
LZS3_k127_4972990_31	880073.Calab_2081	2.249e-19	105.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_4972990_18	595460.RRSWK_05503	1.641e-66	259.0	COG1572@1|root,COG2931@1|root,COG3291@1|root,COG3386@1|root,COG3420@1|root,COG4257@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3420@2|Bacteria,COG4257@2|Bacteria,2J2YS@203682|Planctomycetes	203682|Planctomycetes	P	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972990_44	1306990.BARG01000095_gene9272	7.272e-06	54.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
LZS3_k127_4972990_14	1250005.PHEL85_1699	5.596e-76	269.0	COG4657@1|root,COG4657@2|Bacteria,4PPXA@976|Bacteroidetes,1I9U6@117743|Flavobacteriia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
LZS3_k127_4972990_11	765914.ThisiDRAFT_1931	3.417e-83	281.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1WW5Q@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
LZS3_k127_4972990_23	1250005.PHEL85_1697	3.118e-49	184.0	COG4659@1|root,COG4659@2|Bacteria,4NQKH@976|Bacteroidetes,1IAXX@117743|Flavobacteriia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
LZS3_k127_4972990_8	1049564.TevJSym_aq00700	6.141e-97	347.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
LZS3_k127_4972990_5	1049564.TevJSym_aq00710	3.048e-140	480.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1J4YP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB
LZS3_k127_4972990_2	765911.Thivi_3180	4.938e-179	615.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1141@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1141@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,1MVM0@1224|Proteobacteria,1RNNX@1236|Gammaproteobacteria,1WX9H@135613|Chromatiales	135613|Chromatiales	C	pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
LZS3_k127_4972990_9	349124.Hhal_0067	9.401e-90	304.0	COG1143@1|root,COG2878@1|root,COG1143@2|Bacteria,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria,1WWC5@135613|Chromatiales	135613|Chromatiales	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
LZS3_k127_4972990_10	1049564.TevJSym_bb00030	3.126e-85	314.0	COG1013@1|root,COG1013@2|Bacteria,1R28U@1224|Proteobacteria	1224|Proteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
LZS3_k127_4972990_7	1049564.TevJSym_bb00040	8.783e-103	344.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
LZS3_k127_4972990_0	1049564.TevJSym_bb00050	7.208e-229	725.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
LZS3_k127_4972990_45	936548.HMPREF1136_1234	2.336e-05	54.0	COG1846@1|root,COG1846@2|Bacteria,2GSRN@201174|Actinobacteria,4D5XD@85005|Actinomycetales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
LZS3_k127_4972990_22	306281.AJLK01000072_gene645	3.042e-49	179.0	COG1764@1|root,COG1764@2|Bacteria,1G767@1117|Cyanobacteria,1JKB8@1189|Stigonemataceae	1117|Cyanobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
LZS3_k127_4972990_4	1379270.AUXF01000001_gene2673	6.567e-144	468.0	COG0520@1|root,COG0520@2|Bacteria,1ZSV8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS3_k127_4972990_32	1121403.AUCV01000040_gene4283	3.574e-19	95.0	2FKDJ@1|root,34C0Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_4972990_13	1232410.KI421413_gene485	3.144e-77	268.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria,43UFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
LZS3_k127_4972990_26	1157708.KB907459_gene2048	1.234e-35	152.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2VTR4@28216|Betaproteobacteria,4AEDJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
LZS3_k127_5045249_4	1006006.Mcup_1289	4.945e-05	55.0	COG0457@1|root,arCOG03428@2157|Archaea	2157|Archaea	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
LZS3_k127_5045249_2	880073.Calab_0041	1.47e-20	108.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
LZS3_k127_5045249_1	1173029.JH980292_gene2124	7.909e-27	127.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT,PMT_2
LZS3_k127_5045249_0	1379698.RBG1_1C00001G0608	4.145e-61	229.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
LZS3_k127_5045249_3	83406.HDN1F_02670	6.191e-17	88.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,GerE,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,PocR,Response_reg
LZS3_k127_5049073_8	36874.HQ34_04295	1.151e-17	83.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,2FT2E@200643|Bacteroidia,22Y4Y@171551|Porphyromonadaceae	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
LZS3_k127_5049073_6	314285.KT71_14554	6.945e-37	152.0	28MAS@1|root,318XW@2|Bacteria,1NU47@1224|Proteobacteria,1SM4U@1236|Gammaproteobacteria,1J7Z3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
LZS3_k127_5049073_7	522306.CAP2UW1_1313	8.691e-32	128.0	COG4566@1|root,COG4566@2|Bacteria,1MZ8E@1224|Proteobacteria,2VYAI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_5049073_5	522306.CAP2UW1_1311	5.435e-68	240.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VM61@28216|Betaproteobacteria,1KQQ2@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein LuxR	-	-	-	ko:K13041	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
LZS3_k127_5049073_1	1298867.AUES01000022_gene2882	6.379e-138	461.0	COG2984@1|root,COG4191@1|root,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3JT51@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA
LZS3_k127_5049073_0	1506583.JQJY01000001_gene553	2.768e-167	536.0	COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,1I5BI@117743|Flavobacteriia,2NVIG@237|Flavobacterium	976|Bacteroidetes	S	COG NOG10142 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5049073_2	1121921.KB898706_gene2816	4.364e-126	413.0	COG2066@1|root,COG2066@2|Bacteria,1MWB5@1224|Proteobacteria,1RMY9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
LZS3_k127_5049073_4	700598.Niako_2137	4.902e-83	285.0	2C0ZU@1|root,32R7S@2|Bacteria,4P4KK@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5049073_3	700598.Niako_2130	1.499e-91	317.0	COG3170@1|root,COG3170@2|Bacteria,4P04E@976|Bacteroidetes	976|Bacteroidetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5061216_3	945713.IALB_2573	7.465e-152	506.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS3_k127_5061216_8	1121920.AUAU01000002_gene1985	5.935e-59	208.0	COG2080@1|root,COG2080@2|Bacteria,3Y4U1@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S -binding domain protein	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
LZS3_k127_5061216_9	1484460.JSWG01000006_gene2967	8.055e-55	206.0	COG1266@1|root,COG1266@2|Bacteria,4NGBZ@976|Bacteroidetes,1HZ6J@117743|Flavobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
LZS3_k127_5061216_23	1173024.KI912150_gene1438	2.43e-08	59.0	2EH9Q@1|root,33B1J@2|Bacteria,1GAX5@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5061216_16	1173264.KI913949_gene3816	1.015e-22	102.0	2DYJH@1|root,34A3F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5061216_13	926560.KE387023_gene2407	2.711e-39	153.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
LZS3_k127_5061216_10	215803.DB30_7958	3.657e-51	205.0	COG3391@1|root,COG3391@2|Bacteria,1P80Y@1224|Proteobacteria,43959@68525|delta/epsilon subdivisions,2X4BM@28221|Deltaproteobacteria,2YYPB@29|Myxococcales	1224|Proteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5061216_20	880073.Calab_0921	4.588e-12	79.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_5061216_18	1385518.N798_08205	1.024e-14	78.0	COG0425@1|root,COG0425@2|Bacteria,2GSF4@201174|Actinobacteria,4FHSC@85021|Intrasporangiaceae	201174|Actinobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
LZS3_k127_5061216_11	880073.Calab_0541	4.174e-47	171.0	COG1993@1|root,COG1993@2|Bacteria,2NPXF@2323|unclassified Bacteria	2|Bacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K06199,ko:K09137	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CBS,DUF190
LZS3_k127_5061216_12	671143.DAMO_2926	1.161e-43	162.0	COG0239@1|root,COG0239@2|Bacteria,2NQ56@2323|unclassified Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
LZS3_k127_5061216_0	713586.KB900536_gene1524	3.632e-194	613.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RMP7@1236|Gammaproteobacteria,1X1AI@135613|Chromatiales	135613|Chromatiales	S	HipA N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HipA_C
LZS3_k127_5061216_21	1408428.JNJP01000008_gene2251	1.628e-10	66.0	COG1396@1|root,COG1396@2|Bacteria,1NGG5@1224|Proteobacteria,42XQ8@68525|delta/epsilon subdivisions,2WT94@28221|Deltaproteobacteria,2MFMH@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
LZS3_k127_5061216_1	1191523.MROS_1555	2.518e-187	602.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
LZS3_k127_5061216_2	204669.Acid345_1514	2.967e-153	504.0	COG1132@1|root,COG1132@2|Bacteria,3Y32T@57723|Acidobacteria,2JIBZ@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter, transmembrane	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
LZS3_k127_5061216_7	644966.Tmar_1412	2.093e-64	228.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,3WDH1@538999|Clostridiales incertae sedis	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
LZS3_k127_5061216_26	1280953.HOC_18474	0.0004121	53.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16,TPR_19,TPR_2,TPR_8
LZS3_k127_5061216_17	1112212.JH584235_gene2867	9.755e-15	83.0	COG4566@1|root,COG4566@2|Bacteria,1MZ8E@1224|Proteobacteria,2UBRR@28211|Alphaproteobacteria,2K754@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_5061216_22	945713.IALB_2290	1.311e-08	61.0	2AQ71@1|root,31FCR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5061216_4	945713.IALB_2140	6.497e-146	475.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	metC	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004121,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
LZS3_k127_5061216_5	1128421.JAGA01000004_gene2611	1.038e-119	395.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
LZS3_k127_5061216_25	880073.Calab_2082	3.495e-07	64.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
LZS3_k127_5061216_19	595460.RRSWK_05435	4.983e-14	86.0	2EYTK@1|root,33S0U@2|Bacteria,2IYA9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1
LZS3_k127_5061216_14	497964.CfE428DRAFT_4532	1.351e-36	154.0	COG0737@1|root,COG0737@2|Bacteria,46TFI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
LZS3_k127_5061216_15	1401067.HMPREF0872_01015	2.584e-28	116.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4H539@909932|Negativicutes	909932|Negativicutes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
LZS3_k127_5061216_6	1379698.RBG1_1C00001G0864	8.548e-90	335.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744,ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA,OstA_C
LZS3_k127_5061216_24	1206101.AZXC01000014_gene733	3.455e-08	59.0	COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
LZS3_k127_5252779_0	1125863.JAFN01000001_gene241	4.68e-145	472.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
LZS3_k127_5252779_4	1379698.RBG1_1C00001G0978	2.836e-70	246.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
LZS3_k127_5252779_6	1196323.ALKF01000191_gene5530	8.23e-47	188.0	COG1680@1|root,COG1680@2|Bacteria,1UT07@1239|Firmicutes,4HMEY@91061|Bacilli,26QSV@186822|Paenibacillaceae	91061|Bacilli	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
LZS3_k127_5252779_3	1379698.RBG1_1C00001G0979	7.957e-97	322.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
LZS3_k127_5252779_11	1122621.ATZA01000033_gene507	4.412e-23	112.0	COG1463@1|root,COG1463@2|Bacteria,4NHT9@976|Bacteroidetes,1IQZY@117747|Sphingobacteriia	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
LZS3_k127_5252779_9	1188256.BASI01000003_gene2548	6.802e-36	145.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,3FCMY@34008|Rhodovulum	28211|Alphaproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
LZS3_k127_5252779_8	1545915.JROG01000003_gene970	1.931e-40	156.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2K0Y0@204457|Sphingomonadales	204457|Sphingomonadales	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
LZS3_k127_5252779_1	648996.Theam_0502	2.188e-137	454.0	COG0008@1|root,COG0008@2|Bacteria,2G3SV@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
LZS3_k127_5252779_7	522306.CAP2UW1_3971	1.758e-43	171.0	COG5266@1|root,COG5266@2|Bacteria,1NFTH@1224|Proteobacteria,2VVQE@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
LZS3_k127_5252779_10	1278073.MYSTI_04041	7.101e-29	123.0	2DTU1@1|root,33MMF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5252779_5	479432.Sros_1504	1.171e-49	184.0	COG1280@1|root,COG1280@2|Bacteria,2GMDP@201174|Actinobacteria,4EIVP@85012|Streptosporangiales	201174|Actinobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
LZS3_k127_5252779_2	313606.M23134_05227	5.273e-120	428.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
LZS3_k127_5319893_14	62928.azo1064	1.626e-62	218.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,2KWC2@206389|Rhodocyclales	206389|Rhodocyclales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS3_k127_5319893_0	748247.AZKH_3094	1.798e-318	985.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KVAY@206389|Rhodocyclales	206389|Rhodocyclales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS3_k127_5319893_2	667014.Thein_1592	2.18e-208	667.0	COG0441@1|root,COG0441@2|Bacteria,2GH53@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
LZS3_k127_5319893_17	1379698.RBG1_1C00001G1116	1.282e-56	205.0	COG0290@1|root,COG0290@2|Bacteria,2NPDH@2323|unclassified Bacteria	2|Bacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
LZS3_k127_5319893_23	97139.C824_03113	1.709e-17	85.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,36MNG@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
LZS3_k127_5319893_20	696369.KI912183_gene906	9.012e-39	149.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,2627I@186807|Peptococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
LZS3_k127_5319893_5	273068.TTE1689	1.427e-117	388.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,42EPG@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
LZS3_k127_5319893_4	1121430.JMLG01000012_gene1991	5.726e-159	529.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,2602M@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
LZS3_k127_5319893_25	1120973.AQXL01000099_gene3269	2.011e-11	68.0	COG3027@1|root,COG3027@2|Bacteria,1VFZR@1239|Firmicutes,4HNRI@91061|Bacilli,278K2@186823|Alicyclobacillaceae	91061|Bacilli	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
LZS3_k127_5319893_12	1209989.TepiRe1_1409	3.467e-71	250.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,42EQD@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
LZS3_k127_5319893_7	376686.Fjoh_0243	3.031e-93	316.0	COG0190@1|root,COG0190@2|Bacteria,4NEJP@976|Bacteroidetes,1HY41@117743|Flavobacteriia,2NTKI@237|Flavobacterium	976|Bacteroidetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
LZS3_k127_5319893_8	713586.KB900536_gene3088	5.17e-93	319.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
LZS3_k127_5319893_27	622637.KE124774_gene4020	4.568e-09	66.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,36YRF@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Exonuclease VII small subunit	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
LZS3_k127_5319893_16	882.DVU_1349	2.153e-60	220.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,2M8I7@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
LZS3_k127_5319893_24	329726.AM1_4853	1.708e-16	87.0	COG1963@1|root,COG1963@2|Bacteria,1G5PI@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
LZS3_k127_5319893_1	401526.TcarDRAFT_1596	4.37e-221	705.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H236@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
LZS3_k127_5319893_18	316067.Geob_3461	2.678e-50	196.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
LZS3_k127_5319893_11	398580.Dshi_2413	3.007e-78	284.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2TREW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
LZS3_k127_5319893_19	635013.TherJR_2805	2.671e-49	190.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,267E8@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
LZS3_k127_5319893_3	234267.Acid_4597	1.891e-172	553.0	COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
LZS3_k127_5319893_6	880073.Calab_2000	1.46e-114	381.0	COG0451@1|root,COG0451@2|Bacteria,2NNNX@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	wbpP	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
LZS3_k127_5319893_22	1056512.D515_02301	1.069e-18	98.0	COG1596@1|root,COG1596@2|Bacteria,1PK0J@1224|Proteobacteria,1RM8V@1236|Gammaproteobacteria,1XUG8@135623|Vibrionales	135623|Vibrionales	M	Periplasmic protein involved in polysaccharide export	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
LZS3_k127_5319893_26	1273103.NM10_12128	2.859e-09	70.0	COG3206@1|root,COG3206@2|Bacteria,1V0DA@1239|Firmicutes,4H3KF@909932|Negativicutes	909932|Negativicutes	M	chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
LZS3_k127_5319893_21	880073.Calab_3531	9.417e-35	143.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
LZS3_k127_5319893_13	448385.sce8918	6.025e-67	244.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T1S@68525|delta/epsilon subdivisions,2WPVE@28221|Deltaproteobacteria,2YXW5@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_5319893_9	448385.sce1301	2.846e-80	281.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,42SAM@68525|delta/epsilon subdivisions,2WPCJ@28221|Deltaproteobacteria,2YZP2@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_5319893_10	1242864.D187_007138	2.856e-79	279.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,42PY5@68525|delta/epsilon subdivisions,2WIU8@28221|Deltaproteobacteria,2YVJ5@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	tuaH	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
LZS3_k127_5319893_15	1210884.HG799465_gene12267	8.675e-61	227.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,CarboxypepD_reg,IAT_beta,Invasin_D3,PPC
LZS3_k127_5360232_30	459349.CLOAM1790	1.193e-20	106.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
LZS3_k127_5360232_5	713586.KB900536_gene109	8.758e-118	385.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,1RSP8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
LZS3_k127_5360232_13	945713.IALB_2273	8.238e-66	233.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
LZS3_k127_5360232_25	1125863.JAFN01000001_gene284	2.069e-33	138.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
LZS3_k127_5360232_28	1408473.JHXO01000011_gene3035	3.601e-30	133.0	COG3762@1|root,COG3762@2|Bacteria,4NQIT@976|Bacteroidetes,2FTHS@200643|Bacteroidia	976|Bacteroidetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
LZS3_k127_5360232_7	1123072.AUDH01000024_gene327	3.783e-108	368.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,2JQ32@204441|Rhodospirillales	204441|Rhodospirillales	L	Belongs to the DNA photolyase family	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
LZS3_k127_5360232_27	502025.Hoch_3438	1.057e-30	125.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WT56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_5360232_9	639030.JHVA01000001_gene2197	5.151e-90	314.0	COG0034@1|root,COG0034@2|Bacteria,3Y3RG@57723|Acidobacteria,2JHXM@204432|Acidobacteriia	204432|Acidobacteriia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
LZS3_k127_5360232_22	324602.Caur_3169	7.61e-37	147.0	COG0789@1|root,COG0789@2|Bacteria,2GBIN@200795|Chloroflexi,375XH@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
LZS3_k127_5360232_11	319225.Plut_0256	8.478e-76	282.0	COG1629@1|root,COG4771@2|Bacteria,1FDET@1090|Chlorobi	1090|Chlorobi	P	TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
LZS3_k127_5360232_23	661478.OP10G_0418	4.523e-36	146.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
LZS3_k127_5360232_31	105425.BBPL01000001_gene6351	1.53e-20	102.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,NUDIX
LZS3_k127_5360232_14	1379698.RBG1_1C00001G0796	1.614e-60	213.0	COG1956@1|root,COG1956@2|Bacteria	2|Bacteria	T	GAF domain-containing protein	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
LZS3_k127_5360232_4	234267.Acid_5336	8.629e-146	489.0	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,3Y3IC@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
LZS3_k127_5360232_3	502025.Hoch_2334	1.677e-154	500.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2YUIF@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
LZS3_k127_5360232_8	1123054.KB907703_gene1342	8.544e-94	322.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria,1WVVW@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
LZS3_k127_5360232_10	1254432.SCE1572_39205	1.963e-78	271.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2WUIA@28221|Deltaproteobacteria,2YV7F@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
LZS3_k127_5360232_2	756272.Plabr_3346	2.142e-170	552.0	COG0733@1|root,COG0733@2|Bacteria,2J29X@203682|Planctomycetes	203682|Planctomycetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
LZS3_k127_5360232_1	234267.Acid_5749	3.884e-194	636.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
LZS3_k127_5360232_17	1340493.JNIF01000003_gene1293	9.338e-57	218.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y4DC@57723|Acidobacteria	57723|Acidobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_3,SpoIIE
LZS3_k127_5360232_29	1121930.AQXG01000010_gene3115	7.888e-29	123.0	2E1HF@1|root,32WVJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3996
LZS3_k127_5360232_15	1235802.C823_00919	1.144e-58	211.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,25VGF@186806|Eubacteriaceae	186801|Clostridia	S	neutral zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
LZS3_k127_5360232_21	1123023.JIAI01000007_gene1679	1.723e-41	162.0	COG2263@1|root,COG2263@2|Bacteria	2|Bacteria	J	DNA repair	-	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
LZS3_k127_5360232_33	335543.Sfum_0970	1.562e-12	81.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,43BSH@68525|delta/epsilon subdivisions,2X73A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
LZS3_k127_5360232_12	926560.KE387027_gene665	4.706e-70	246.0	28JJ5@1|root,2Z9C9@2|Bacteria,1WJSQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	infection protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5360232_16	404589.Anae109_2479	3.593e-58	212.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_5360232_6	756272.Plabr_3195	1.481e-113	381.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
LZS3_k127_5360232_20	264462.Bd2816	2.184e-43	169.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2MTSY@213481|Bdellovibrionales,2WM0M@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	mechanosensitive ion channel	mscS-2	-	-	-	-	-	-	-	-	-	-	-	MS_channel
LZS3_k127_5360232_0	1237149.C900_04408	0.0	1748.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFHX@976|Bacteroidetes,47KS7@768503|Cytophagia	976|Bacteroidetes	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
LZS3_k127_5360232_19	1121957.ATVL01000014_gene1459	1.288e-46	183.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5360232_26	1454004.AW11_01231	5.571e-31	135.0	COG1361@1|root,COG2931@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2VH0Q@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
LZS3_k127_5360232_34	1047013.AQSP01000058_gene2028	3.602e-11	75.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,TolB_like
LZS3_k127_5360232_32	1416759.AYMR01000007_gene697	2.082e-16	93.0	COG3391@1|root,COG3468@1|root,COG4870@1|root,COG4932@1|root,COG3391@2|Bacteria,COG3468@2|Bacteria,COG4870@2|Bacteria,COG4932@2|Bacteria,2HCJX@201174|Actinobacteria,4FTDJ@85023|Microbacteriaceae	201174|Actinobacteria	MU	ig-like, plexins, transcription factors	-	-	-	-	-	-	-	-	-	-	-	-	TIG
LZS3_k127_5360232_18	1185876.BN8_00045	1.382e-50	184.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,47RAN@768503|Cytophagia	976|Bacteroidetes	J	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
LZS3_k127_5362333_3	1267535.KB906767_gene1301	1.576e-42	168.0	COG0122@1|root,COG0122@2|Bacteria,3Y7N6@57723|Acidobacteria	57723|Acidobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
LZS3_k127_5362333_1	945713.IALB_2228	2.955e-63	229.0	COG0471@1|root,COG0471@2|Bacteria	2|Bacteria	P	metal ion transport	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS3_k127_5362333_4	1238184.CM001792_gene2669	6.365e-41	169.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,4H9UV@91061|Bacilli,23JC4@182709|Oceanobacillus	91061|Bacilli	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
LZS3_k127_5362333_5	1121405.dsmv_2929	9.323e-27	116.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,42WCG@68525|delta/epsilon subdivisions,2WS1H@28221|Deltaproteobacteria,2MMDB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
LZS3_k127_5362333_2	649638.Trad_2364	6.991e-57	208.0	COG1752@1|root,COG1752@2|Bacteria,1WMRT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG1752 esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
LZS3_k127_5362333_0	518766.Rmar_2521	5.477e-164	532.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1FKC5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
LZS3_k127_5362333_6	1125971.ASJB01000099_gene2286	1.61e-21	107.0	COG0842@1|root,COG0842@2|Bacteria,2I0HP@201174|Actinobacteria,4E1P2@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS3_k127_5362333_7	2002.JOEQ01000004_gene2895	0.0006339	46.0	COG1511@1|root,COG1511@2|Bacteria,2GKEM@201174|Actinobacteria,4EH8X@85012|Streptosporangiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,DUF3533
LZS3_k127_5396474_12	573413.Spirs_3120	1.039e-37	154.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	tnp3503b	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Transposase_mut
LZS3_k127_5396474_16	483219.LILAB_16975	3.631e-28	132.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
LZS3_k127_5396474_25	926554.KI912670_gene2061	1.267e-07	64.0	COG2374@1|root,COG4085@1|root,COG2374@2|Bacteria,COG4085@2|Bacteria	2|Bacteria	S	PFAM nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,Big_3_5,Big_5,Endonuclease_1,Gly_rich,LTD,Mfa_like_1
LZS3_k127_5396474_27	1123057.P872_06825	0.0001312	55.0	COG4288@1|root,COG4288@2|Bacteria,4NHM6@976|Bacteroidetes,47KV2@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CHU_C,LTD
LZS3_k127_5396474_3	309801.trd_A0452	1.002e-155	500.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27YSW@189775|Thermomicrobia	189775|Thermomicrobia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS3_k127_5396474_5	1125863.JAFN01000001_gene568	4.658e-129	424.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
LZS3_k127_5396474_11	1292034.OR37_00938	1.88e-40	156.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,2KGGP@204458|Caulobacterales	204458|Caulobacterales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
LZS3_k127_5396474_19	246197.MXAN_1545	6.876e-21	105.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42T6S@68525|delta/epsilon subdivisions,2WP34@28221|Deltaproteobacteria,2YV20@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	yrdC1	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
LZS3_k127_5396474_18	456320.Mvol_0239	1.576e-24	114.0	COG0535@1|root,arCOG00938@2157|Archaea,2Y12G@28890|Euryarchaeota,23R8Z@183939|Methanococci	183939|Methanococci	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
LZS3_k127_5396474_8	1379270.AUXF01000004_gene3153	4.239e-68	254.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
LZS3_k127_5396474_14	1125863.JAFN01000001_gene536	5.426e-31	136.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_5396474_24	926566.Terro_2436	2.695e-12	74.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
LZS3_k127_5396474_20	1121406.JAEX01000001_gene239	2.845e-19	97.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,1RCYA@1224|Proteobacteria,43AXU@68525|delta/epsilon subdivisions,2X6C0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
LZS3_k127_5396474_22	1379698.RBG1_1C00001G0404	8.28e-18	90.0	2EAFJ@1|root,334IY@2|Bacteria,2NRZR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
LZS3_k127_5396474_9	502025.Hoch_1731	8.199e-68	254.0	COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2WMAP@28221|Deltaproteobacteria,2Z2YY@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,Phenol_MetA_deg,TSP_3,VWA
LZS3_k127_5396474_28	172045.KS04_12565	0.0001656	53.0	COG0697@1|root,COG0697@2|Bacteria,4PKRH@976|Bacteroidetes,1HX4A@117743|Flavobacteriia,34Q52@308865|Elizabethkingia	976|Bacteroidetes	EG	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
LZS3_k127_5396474_23	118173.KB235910_gene4373	3.986e-17	93.0	COG1595@1|root,COG1595@2|Bacteria,1G5PA@1117|Cyanobacteria,1HB18@1150|Oscillatoriales	1117|Cyanobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
LZS3_k127_5396474_13	290397.Adeh_2115	4.596e-33	142.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS3_k127_5396474_10	1217720.ALOX01000010_gene1990	1.213e-56	207.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2JPGN@204441|Rhodospirillales	204441|Rhodospirillales	S	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
LZS3_k127_5396474_1	235909.GK3085	3.73e-269	872.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,1WF5U@129337|Geobacillus	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS3_k127_5396474_6	479434.Sthe_1770	1.711e-100	344.0	COG1087@1|root,COG1087@2|Bacteria,2G80W@200795|Chloroflexi,27Y6Y@189775|Thermomicrobia	189775|Thermomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
LZS3_k127_5396474_2	1168034.FH5T_10945	3.33e-216	691.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,2FM68@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
LZS3_k127_5396474_17	1499967.BAYZ01000016_gene6551	1.627e-26	119.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
LZS3_k127_5396474_7	1094980.Mpsy_0919	3.894e-80	287.0	COG0248@1|root,arCOG05138@2157|Archaea,2XZYT@28890|Euryarchaeota,2NAE7@224756|Methanomicrobia	224756|Methanomicrobia	F	Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
LZS3_k127_5396474_26	1235803.C825_02629	0.0001134	55.0	COG5000@1|root,COG5000@2|Bacteria,4NE49@976|Bacteroidetes,2G2UI@200643|Bacteroidia,231JX@171551|Porphyromonadaceae	976|Bacteroidetes	T	GHKL domain	zraS_1	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_5396474_15	1347369.CCAD010000050_gene330	2.775e-28	132.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HBZ0@91061|Bacilli,1ZAQC@1386|Bacillus	91061|Bacilli	T	Histidine kinase	resE	-	2.7.13.3	ko:K07651	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
LZS3_k127_5396474_21	66897.DJ64_30185	2.531e-18	90.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_5396474_4	1191523.MROS_1186	2.846e-155	505.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
LZS3_k127_5396474_0	880073.Calab_1598	0.0	1157.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
LZS3_k127_5396474_29	573413.Spirs_3993	0.0003683	45.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	tnp3503b	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Transposase_mut
LZS3_k127_5492107_4	391625.PPSIR1_09331	7.795e-19	98.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria	2|Bacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_1532,iJN746.PP_3282	3HCDH,3HCDH_N
LZS3_k127_5492107_2	1232410.KI421426_gene1504	5.766e-31	124.0	2DXYD@1|root,3476T@2|Bacteria,1NCGD@1224|Proteobacteria	1224|Proteobacteria	S	Sugar efflux transporter for intercellular exchange	-	-	-	-	-	-	-	-	-	-	-	-	MtN3_slv
LZS3_k127_5492107_1	1906.SFRA_31215	8.959e-85	289.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	-	-	-	ko:K11021,ko:K16267	-	-	-	-	ko00000,ko02000,ko02042	2.A.5.4.11	-	-	Zip
LZS3_k127_5492107_0	335543.Sfum_2670	2.287e-165	530.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2MQ8M@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism	-	-	4.4.1.11,4.4.1.8	ko:K01760,ko:K01761	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00654,R00782,R01286,R02408,R04770,R04941	RC00056,RC00069,RC00196,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
LZS3_k127_5492107_3	644282.Deba_2614	3.297e-21	96.0	COG1342@1|root,COG1342@2|Bacteria,1N80T@1224|Proteobacteria,42WDZ@68525|delta/epsilon subdivisions,2WSGS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function  DUF134	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
LZS3_k127_5492107_5	324925.Ppha_1324	2.048e-13	71.0	COG1433@1|root,COG1433@2|Bacteria,1FF7W@1090|Chlorobi	1090|Chlorobi	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
LZS3_k127_5524862_12	927658.AJUM01000037_gene2274	4.495e-150	483.0	COG2403@1|root,COG2403@2|Bacteria,4NHIW@976|Bacteroidetes,2FNNX@200643|Bacteroidia	976|Bacteroidetes	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5524862_17	1168034.FH5T_10930	2.232e-129	423.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,2FNFG@200643|Bacteroidia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
LZS3_k127_5524862_21	1521187.JPIM01000102_gene3720	2.112e-117	386.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,375DE@32061|Chloroflexia	32061|Chloroflexia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
LZS3_k127_5524862_75	760568.Desku_0214	3.16e-34	136.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,24JM5@186801|Clostridia,261SD@186807|Peptococcaceae	186801|Clostridia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
LZS3_k127_5524862_85	1379270.AUXF01000006_gene248	2.478e-23	106.0	COG1399@1|root,COG1399@2|Bacteria,1ZTSW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
LZS3_k127_5524862_87	1379698.RBG1_1C00001G1829	2.347e-20	92.0	COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal L32p protein family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
LZS3_k127_5524862_28	1000569.HMPREF1040_0413	1.121e-98	334.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4H1ZZ@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
LZS3_k127_5524862_23	243231.GSU1601	3.243e-114	377.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,43S1E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH-2	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
LZS3_k127_5524862_35	398720.MED217_01850	1.854e-76	271.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,1HWU7@117743|Flavobacteriia,2XIPW@283735|Leeuwenhoekiella	976|Bacteroidetes	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
LZS3_k127_5524862_42	742726.HMPREF9448_01905	2.016e-72	252.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia,22WN3@171551|Porphyromonadaceae	976|Bacteroidetes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_5524862_81	1123255.JHYS01000004_gene926	6.204e-25	105.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,4AF2T@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
LZS3_k127_5524862_10	1379698.RBG1_1C00001G1824	9.256e-152	490.0	COG0304@1|root,COG0304@2|Bacteria,2NNSX@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
LZS3_k127_5524862_57	1307761.L21SP2_1753	2.951e-51	194.0	COG0571@1|root,COG0571@2|Bacteria,2J6UI@203691|Spirochaetes	203691|Spirochaetes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
LZS3_k127_5524862_93	880073.Calab_1070	2.082e-11	76.0	COG2067@1|root,COG2067@2|Bacteria,2NRR0@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
LZS3_k127_5524862_70	1297742.A176_02761	5.783e-37	158.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
LZS3_k127_5524862_71	518766.Rmar_2628	9.613e-37	152.0	COG1595@1|root,COG1595@2|Bacteria,4NQE0@976|Bacteroidetes,1FISP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_5524862_92	518766.Rmar_1051	1.004e-11	76.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,1FJ29@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
LZS3_k127_5524862_94	760142.Hipma_0228	1.815e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,1Q6R4@1224|Proteobacteria,439NS@68525|delta/epsilon subdivisions,2X504@28221|Deltaproteobacteria,2M74N@213113|Desulfurellales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_19,TPR_8
LZS3_k127_5524862_51	1069534.LRC_08280	1.681e-62	220.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli,3F422@33958|Lactobacillaceae	91061|Bacilli	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
LZS3_k127_5524862_67	1283300.ATXB01000001_gene805	1.411e-37	147.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1XF4V@135618|Methylococcales	135618|Methylococcales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
LZS3_k127_5524862_19	1125863.JAFN01000001_gene3029	2.441e-121	400.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS3_k127_5524862_8	1457393.AZ09_09655	2.183e-171	549.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2JPBR@204441|Rhodospirillales	204441|Rhodospirillales	I	Biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
LZS3_k127_5524862_14	1120973.AQXL01000128_gene2790	6.561e-134	454.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,277W0@186823|Alicyclobacillaceae	91061|Bacilli	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
LZS3_k127_5524862_32	1192034.CAP_5305	1.838e-82	290.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2YUDC@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
LZS3_k127_5524862_97	1545915.JROG01000009_gene2738	5.288e-07	60.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,2JZVK@204457|Sphingomonadales	204457|Sphingomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
LZS3_k127_5524862_77	679201.HMPREF9334_00426	5.501e-31	133.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4H2AC@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS3_k127_5524862_5	861299.J421_1151	1.113e-213	700.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1ZTCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
LZS3_k127_5524862_82	1463909.KL585961_gene5986	7.711e-25	113.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
LZS3_k127_5524862_22	1304880.JAGB01000002_gene2070	5.354e-115	380.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
LZS3_k127_5524862_9	324925.Ppha_1733	5.227e-170	550.0	COG1190@1|root,COG1190@2|Bacteria,1FDK1@1090|Chlorobi	1090|Chlorobi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
LZS3_k127_5524862_37	671143.DAMO_1656	4.051e-75	274.0	COG4591@1|root,COG4591@2|Bacteria,2NP18@2323|unclassified Bacteria	2|Bacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
LZS3_k127_5524862_45	1236541.BALL01000025_gene2988	5.73e-71	246.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,2Q8IK@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
LZS3_k127_5524862_76	351627.Csac_2369	4.334e-31	130.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,24JE8@186801|Clostridia,42G0X@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
LZS3_k127_5524862_30	1123242.JH636434_gene3291	1.635e-86	299.0	COG3869@1|root,COG3869@2|Bacteria,2IXJG@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
LZS3_k127_5524862_1	997296.PB1_06802	2.475e-321	1006.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1ZB4C@1386|Bacillus	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
LZS3_k127_5524862_18	1379698.RBG1_1C00001G1846	8.888e-126	430.0	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS3_k127_5524862_80	1379698.RBG1_1C00001G1847	1.078e-26	115.0	COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
LZS3_k127_5524862_27	1379698.RBG1_1C00001G1848	2.629e-101	340.0	COG1044@1|root,COG1044@2|Bacteria,2NNSF@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	ic_1306.c0216	Hexapep,Hexapep_2,LpxD
LZS3_k127_5524862_15	1379698.RBG1_1C00001G1649	3.542e-132	435.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
LZS3_k127_5524862_33	1123288.SOV_3c03730	7.948e-82	280.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes	909932|Negativicutes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep,Hexapep_2
LZS3_k127_5524862_41	379066.GAU_1590	1.228e-72	256.0	COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
LZS3_k127_5524862_40	525897.Dbac_2423	6.998e-73	260.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,2M8K0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
LZS3_k127_5524862_65	1379698.RBG1_1C00001G1645	4.213e-39	164.0	COG2121@1|root,COG2121@2|Bacteria,2NPP6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF374)	MA20_05800	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527,ko:K09778	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	DUF374
LZS3_k127_5524862_68	671143.DAMO_1643	1.774e-37	160.0	COG1663@1|root,COG1663@2|Bacteria,2NPF0@2323|unclassified Bacteria	2|Bacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396	LpxK
LZS3_k127_5524862_7	290512.Paes_0702	1.346e-176	568.0	COG0029@1|root,COG0029@2|Bacteria,1FD79@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
LZS3_k127_5524862_62	1121346.KB899811_gene1559	5.748e-43	166.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,274IB@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS3_k127_5524862_79	861299.J421_3229	6.969e-27	126.0	COG4365@1|root,COG4365@2|Bacteria,1ZTG0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacillithiol biosynthesis BshC	-	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
LZS3_k127_5524862_59	1295642.H839_11454	2.265e-45	173.0	COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,1WF5D@129337|Geobacillus	91061|Bacilli	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
LZS3_k127_5524862_20	1191523.MROS_0374	2.073e-117	388.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_5524862_89	247490.KSU1_B0637	1.124e-17	89.0	2E5IJ@1|root,3309Y@2|Bacteria,2J0P5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5524862_66	867903.ThesuDRAFT_00686	1.856e-38	151.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3WCKF@538999|Clostridiales incertae sedis	186801|Clostridia	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
LZS3_k127_5524862_0	290397.Adeh_1230	0.0	1041.0	COG2766@1|root,COG2766@2|Bacteria,1MVW7@1224|Proteobacteria,42NBQ@68525|delta/epsilon subdivisions,2WKR5@28221|Deltaproteobacteria,2YUIB@29|Myxococcales	28221|Deltaproteobacteria	T	PrkA AAA domain	prkA	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
LZS3_k127_5524862_11	1128421.JAGA01000002_gene89	9.504e-151	484.0	COG2718@1|root,COG2718@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF444)	yhbH	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444,Haem_oxygenas_2
LZS3_k127_5524862_6	575540.Isop_2730	5.486e-190	605.0	COG2719@1|root,COG2719@2|Bacteria,2IXSH@203682|Planctomycetes	203682|Planctomycetes	S	PFAM SpoVR like protein	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
LZS3_k127_5524862_64	1121448.DGI_1645	2.285e-40	156.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2WP66@28221|Deltaproteobacteria,2MB3T@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
LZS3_k127_5524862_56	945713.IALB_2615	1.756e-51	192.0	COG1355@1|root,COG1355@2|Bacteria	2|Bacteria	C	regulation of microtubule-based process	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
LZS3_k127_5524862_95	452637.Oter_0090	2.779e-08	66.0	2DN50@1|root,32VJ4@2|Bacteria,46TKZ@74201|Verrucomicrobia,3K748@414999|Opitutae	414999|Opitutae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
LZS3_k127_5524862_31	1125863.JAFN01000001_gene2144	2.025e-84	299.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	transport system involved in gliding motility, auxiliary	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
LZS3_k127_5524862_50	671143.DAMO_0837	9.897e-68	245.0	COG1277@1|root,COG1277@2|Bacteria,2NPGK@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
LZS3_k127_5524862_29	671143.DAMO_0838	2.924e-92	313.0	COG1131@1|root,COG1131@2|Bacteria,2NNKB@2323|unclassified Bacteria	2|Bacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ccmA	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
LZS3_k127_5524862_48	1379698.RBG1_1C00001G1613	2.019e-69	257.0	COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria	2|Bacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,PEGA,Pkinase
LZS3_k127_5524862_34	1267535.KB906767_gene1253	1.336e-77	272.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
LZS3_k127_5524862_83	479434.Sthe_2271	4.185e-24	118.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_5524862_91	867845.KI911784_gene2389	4.037e-13	76.0	COG0071@1|root,COG0071@2|Bacteria,2GBQD@200795|Chloroflexi,37615@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
LZS3_k127_5524862_3	1379698.RBG1_1C00001G0646	1.245e-253	812.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
LZS3_k127_5524862_98	398767.Glov_1955	1.48e-05	57.0	COG0859@1|root,COG0859@2|Bacteria,1PQIG@1224|Proteobacteria,42MUM@68525|delta/epsilon subdivisions,2WPZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
LZS3_k127_5524862_13	401526.TcarDRAFT_0104	2.801e-136	455.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
LZS3_k127_5524862_60	626418.bglu_1g29820	3.19e-45	181.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,1K2BX@119060|Burkholderiaceae	28216|Betaproteobacteria	M	heptosyltransferase II	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_5524862_55	290397.Adeh_2611	8.921e-52	196.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
LZS3_k127_5524862_72	290397.Adeh_2610	1.657e-36	147.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
LZS3_k127_5524862_63	941449.dsx2_2713	1.066e-40	166.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,2M7UD@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_5524862_86	234267.Acid_6381	3.736e-21	106.0	COG0859@1|root,COG0859@2|Bacteria,3Y6NF@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
LZS3_k127_5524862_54	880073.Calab_2957	4.145e-60	222.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_5524862_47	1379698.RBG1_1C00001G1249	9.113e-70	248.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
LZS3_k127_5524862_99	1279009.ADICEAN_01888	1.989e-05	57.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
LZS3_k127_5524862_43	404589.Anae109_1412	7.704e-72	249.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
LZS3_k127_5524862_84	909663.KI867150_gene2273	1.193e-23	113.0	COG1596@1|root,COG1596@2|Bacteria,1R6M3@1224|Proteobacteria,42SBA@68525|delta/epsilon subdivisions,2WPHA@28221|Deltaproteobacteria,2MS2V@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Polysaccharide biosynthesis export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
LZS3_k127_5524862_90	1293054.HSACCH_02384	8.879e-14	84.0	COG3206@1|root,COG3206@2|Bacteria,1V0DA@1239|Firmicutes,25CQX@186801|Clostridia,3WAJ9@53433|Halanaerobiales	186801|Clostridia	M	lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
LZS3_k127_5524862_46	1307759.JOMJ01000004_gene2488	9.184e-71	248.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42NNX@68525|delta/epsilon subdivisions,2WJ9P@28221|Deltaproteobacteria,2M9N2@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	secretion ATPase, PEP-CTERM locus subfamily	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
LZS3_k127_5524862_88	1121448.DGI_1959	7.141e-18	94.0	COG0489@1|root,COG0489@2|Bacteria,1MZ64@1224|Proteobacteria,432Z4@68525|delta/epsilon subdivisions,2WXW1@28221|Deltaproteobacteria,2MDQQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	AAA domain	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31
LZS3_k127_5524862_52	240016.ABIZ01000001_gene5365	2.562e-61	225.0	COG1524@1|root,COG1524@2|Bacteria,46XAN@74201|Verrucomicrobia,2IV7D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_5524862_78	313628.LNTAR_11821	3.418e-29	134.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
LZS3_k127_5524862_39	1340493.JNIF01000003_gene2680	4.535e-74	261.0	COG1215@1|root,COG1215@2|Bacteria,3Y5K6@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_5524862_74	300852.55772025	2.844e-35	149.0	COG0438@1|root,COG0438@2|Bacteria,1WJN6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_5524862_73	383372.Rcas_1627	2.474e-36	153.0	COG0438@1|root,COG0438@2|Bacteria,2G7W9@200795|Chloroflexi,3772B@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
LZS3_k127_5524862_24	479434.Sthe_1140	6.956e-107	357.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_5524862_49	1519464.HY22_10230	6.545e-69	243.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1FEH6@1090|Chlorobi	1090|Chlorobi	GM	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
LZS3_k127_5524862_26	765420.OSCT_0007	1.068e-101	342.0	COG0673@1|root,COG0673@2|Bacteria,2G6PI@200795|Chloroflexi,377TM@32061|Chloroflexia	32061|Chloroflexia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_5524862_58	1380356.JNIK01000004_gene179	5.855e-50	194.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4EW89@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_5524862_53	997884.HMPREF1068_02552	9.258e-61	222.0	COG0535@1|root,COG0535@2|Bacteria,4NEKZ@976|Bacteroidetes,2FNV0@200643|Bacteroidia,4AP4J@815|Bacteroidaceae	976|Bacteroidetes	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
LZS3_k127_5524862_44	1195236.CTER_1970	9.912e-72	259.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_5524862_96	1034347.CAHJ01000092_gene1611	7.631e-08	61.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5524862_61	335543.Sfum_0219	1.567e-43	178.0	COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2MRX9@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_5524862_2	640510.BC1001_4662	1.761e-292	916.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,1K008@119060|Burkholderiaceae	28216|Betaproteobacteria	CH	Catalyzes the conversion of salicylyl-CoA to gentisyl-CoA	abmA	-	1.14.13.40,1.3.1.34	ko:K00219,ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
LZS3_k127_5524862_36	402626.Rpic_3832	6.424e-76	264.0	COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,2VM6S@28216|Betaproteobacteria,1K3I3@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	abmB	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.30	ko:K00019,ko:K07535	ko00072,ko00362,ko00650,ko01100,ko01120,ko01220,map00072,map00362,map00650,map01100,map01120,map01220	M00088,M00540	R01361,R05582	RC00117,RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
LZS3_k127_5524862_25	504728.K649_11965	7.026e-105	346.0	COG1024@1|root,COG1024@2|Bacteria,1WIYN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
LZS3_k127_5524862_16	266117.Rxyl_2278	7.661e-132	430.0	COG1960@1|root,COG1960@2|Bacteria,2GK1M@201174|Actinobacteria,4CSG2@84995|Rubrobacteria	84995|Rubrobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_5524862_69	604331.AUHY01000006_gene830	4.246e-37	145.0	COG0251@1|root,COG0251@2|Bacteria,1WND4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
LZS3_k127_5524862_4	1254432.SCE1572_12170	9.531e-235	739.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MCF@68525|delta/epsilon subdivisions,2WJRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	bamY	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2143	AMP-binding,AMP-binding_C
LZS3_k127_5524862_38	1192034.CAP_0949	1.386e-74	259.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS3_k127_5691368_0	1089550.ATTH01000001_gene1831	2.164e-191	639.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
LZS3_k127_5691368_15	1089550.ATTH01000001_gene1830	1.284e-66	248.0	COG1595@1|root,COG1595@2|Bacteria,4NSN4@976|Bacteroidetes	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
LZS3_k127_5691368_7	1487953.JMKF01000045_gene2705	1.221e-102	344.0	COG0530@1|root,COG0530@2|Bacteria,1G1Y9@1117|Cyanobacteria,1H7D3@1150|Oscillatoriales	1117|Cyanobacteria	P	K -dependent Na Ca exchanger	ecm27	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
LZS3_k127_5691368_6	330214.NIDE0856	1.946e-105	351.0	COG0306@1|root,COG0306@2|Bacteria,3J1D1@40117|Nitrospirae	40117|Nitrospirae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
LZS3_k127_5691368_21	204669.Acid345_3130	1.266e-50	187.0	COG1392@1|root,COG1392@2|Bacteria,3Y58U@57723|Acidobacteria,2JK4H@204432|Acidobacteriia	204432|Acidobacteriia	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
LZS3_k127_5691368_40	880073.Calab_2081	7.373e-16	93.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_5691368_3	926550.CLDAP_04870	1.301e-118	415.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
LZS3_k127_5691368_2	880073.Calab_3349	7.199e-152	500.0	COG0457@1|root,COG0457@2|Bacteria	880073.Calab_3349|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5691368_45	1123242.JH636434_gene5235	2.359e-05	57.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
LZS3_k127_5691368_13	521011.Mpal_0423	1.621e-73	264.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
LZS3_k127_5691368_5	1121957.ATVL01000014_gene1459	4.212e-108	383.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5691368_41	518766.Rmar_0354	3.574e-14	87.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.62	ko:K01342,ko:K12287,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02044,ko03110	-	-	-	FG-GAP,PPC,Peptidase_C2,Peptidase_S8,VCBS
LZS3_k127_5691368_30	1191523.MROS_0972	1.115e-35	158.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_S8
LZS3_k127_5691368_27	521045.Kole_1995	6.034e-38	161.0	COG1649@1|root,COG1649@2|Bacteria,2GCSB@200918|Thermotogae	200918|Thermotogae	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
LZS3_k127_5691368_35	665571.STHERM_c05220	1.207e-26	119.0	COG0203@1|root,COG0203@2|Bacteria,2J841@203691|Spirochaetes	203691|Spirochaetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
LZS3_k127_5691368_8	1379698.RBG1_1C00001G1568	1.383e-101	342.0	COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
LZS3_k127_5691368_12	335543.Sfum_1581	9.647e-76	259.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2MRHQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
LZS3_k127_5691368_23	390989.JOEG01000009_gene1231	7.865e-50	181.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4DCRK@85008|Micromonosporales	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
LZS3_k127_5691368_26	1158318.ATXC01000001_gene1250	4.076e-41	155.0	COG0099@1|root,COG0099@2|Bacteria,2G428@200783|Aquificae	200783|Aquificae	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
LZS3_k127_5691368_44	1121451.DESAM_22974	8.89e-10	63.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2MDXC@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
LZS3_k127_5691368_31	1382315.JPOI01000001_gene729	6.474e-31	122.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,1WGUD@129337|Geobacillus	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
LZS3_k127_5691368_9	748449.Halha_0210	1.013e-84	296.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WA6N@53433|Halanaerobiales	186801|Clostridia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
LZS3_k127_5691368_14	429009.Adeg_1237	1.126e-67	236.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,42ES7@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
LZS3_k127_5691368_1	1499967.BAYZ01000114_gene2902	3.676e-183	582.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
LZS3_k127_5691368_24	338966.Ppro_0699	4.277e-44	164.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2WQQ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
LZS3_k127_5691368_42	1121926.AXWO01000002_gene1575	3.684e-11	66.0	COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4EZ1S@85014|Glycomycetales	201174|Actinobacteria	J	Ribosomal protein L30p/L7e	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
LZS3_k127_5691368_20	379066.GAU_0890	5.576e-58	208.0	COG0098@1|root,COG0098@2|Bacteria,1ZTHD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
LZS3_k127_5691368_32	1519439.JPJG01000018_gene260	4.871e-30	124.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,2N7DA@216572|Oscillospiraceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
LZS3_k127_5691368_19	663610.JQKO01000001_gene937	2.254e-58	211.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2TV09@28211|Alphaproteobacteria,3NAIJ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
LZS3_k127_5691368_25	1304284.L21TH_0906	2.986e-43	162.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,36I6W@31979|Clostridiaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
LZS3_k127_5691368_37	671143.DAMO_0552	2.466e-24	104.0	COG0199@1|root,COG0199@2|Bacteria,2NPW7@2323|unclassified Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
LZS3_k127_5691368_11	635013.TherJR_0308	9.768e-78	263.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,2603I@186807|Peptococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
LZS3_k127_5691368_33	1121472.AQWN01000002_gene2051	7.992e-29	119.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,26260@186807|Peptococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
LZS3_k127_5691368_22	1121104.AQXH01000010_gene2437	2.855e-50	181.0	COG0093@1|root,COG0093@2|Bacteria,4NNM6@976|Bacteroidetes,1ISEA@117747|Sphingobacteriia	976|Bacteroidetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
LZS3_k127_5691368_34	525373.HMPREF0766_10452	1.425e-28	117.0	COG0186@1|root,COG0186@2|Bacteria,4NSB2@976|Bacteroidetes,1IT9T@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
LZS3_k127_5691368_43	1123239.KB898634_gene2900	1.717e-10	63.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli	91061|Bacilli	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
LZS3_k127_5691368_16	1379698.RBG1_1C00001G1589	4.487e-65	224.0	COG0197@1|root,COG0197@2|Bacteria,2NPC6@2323|unclassified Bacteria	2|Bacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
LZS3_k127_5691368_10	1279038.KB907344_gene3687	1.663e-84	285.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,2JQ8H@204441|Rhodospirillales	204441|Rhodospirillales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
LZS3_k127_5691368_38	298655.KI912266_gene318	8.579e-23	102.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4ET3T@85013|Frankiales	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
LZS3_k127_5691368_29	1131269.AQVV01000036_gene1504	5.388e-36	138.0	COG0185@1|root,COG0185@2|Bacteria	2|Bacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
LZS3_k127_5691368_4	1307759.JOMJ01000003_gene414	1.495e-112	376.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2M8B7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
LZS3_k127_5691368_39	644282.Deba_2936	3.935e-21	104.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
LZS3_k127_5691368_18	411463.EUBVEN_00887	9.583e-59	210.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,25VEH@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
LZS3_k127_5691368_17	1111121.HMPREF1247_0658	2.658e-63	225.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4CUQE@84998|Coriobacteriia	84998|Coriobacteriia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
LZS3_k127_5691368_28	880073.Calab_2125	2.366e-37	143.0	COG0051@1|root,COG0051@2|Bacteria,2NPJY@2323|unclassified Bacteria	2|Bacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
LZS3_k127_5691368_36	204669.Acid345_1224	8.191e-25	104.0	COG0050@1|root,COG0050@2|Bacteria,3Y2JG@57723|Acidobacteria,2JKFY@204432|Acidobacteriia	204432|Acidobacteriia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
LZS3_k127_5742440_36	419610.Mext_0173	0.0008668	42.0	2DM50@1|root,31R6R@2|Bacteria,1N0T3@1224|Proteobacteria,2UD9J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5742440_20	1121377.KB906433_gene675	2.843e-53	194.0	COG0491@1|root,COG0491@2|Bacteria,1WIMP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG0491 Zn-dependent hydrolase including glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
LZS3_k127_5742440_23	404589.Anae109_0107	1.836e-49	189.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C
LZS3_k127_5742440_5	1173024.KI912149_gene5480	4.93e-133	434.0	COG0372@1|root,COG0372@2|Bacteria,1G1DI@1117|Cyanobacteria,1JHS4@1189|Stigonemataceae	1117|Cyanobacteria	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iJN678.gltA	Citrate_synt
LZS3_k127_5742440_0	234267.Acid_3107	1.436e-237	744.0	COG2225@1|root,COG2225@2|Bacteria,3Y4MK@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the malate synthase family	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
LZS3_k127_5742440_4	1329516.JPST01000005_gene1458	1.389e-177	567.0	COG2224@1|root,COG2224@2|Bacteria,1TP1U@1239|Firmicutes,4HBBD@91061|Bacilli,27BEB@186824|Thermoactinomycetaceae	91061|Bacilli	C	Isocitrate lyase family	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
LZS3_k127_5742440_8	1047013.AQSP01000139_gene2392	4.675e-104	355.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
LZS3_k127_5742440_28	1479235.KK366039_gene2850	7.338e-27	111.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,1SCF7@1236|Gammaproteobacteria,1XM1J@135619|Oceanospirillales	135619|Oceanospirillales	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
LZS3_k127_5742440_25	290397.Adeh_4042	1.273e-37	160.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS3_k127_5742440_32	1122975.AQVC01000003_gene1319	1.045e-06	61.0	COG4774@1|root,COG4774@2|Bacteria,4PKNF@976|Bacteroidetes,2G0UR@200643|Bacteroidia,23258@171551|Porphyromonadaceae	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
LZS3_k127_5742440_13	247490.KSU1_D0187	6.104e-73	253.0	COG2220@1|root,COG2220@2|Bacteria,2IZ66@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
LZS3_k127_5742440_1	1121939.L861_17285	2.056e-190	605.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1RRDD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
LZS3_k127_5742440_3	1128421.JAGA01000001_gene2399	5.908e-182	578.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4620	FAA_hydrolase,FAA_hydrolase_N
LZS3_k127_5742440_16	204669.Acid345_2006	6.373e-68	241.0	COG0124@1|root,COG0124@2|Bacteria,3Y4H5@57723|Acidobacteria,2JMV1@204432|Acidobacteriia	204432|Acidobacteriia	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5742440_6	502025.Hoch_0089	2.391e-130	431.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42T5F@68525|delta/epsilon subdivisions,2WQVP@28221|Deltaproteobacteria,2YU42@29|Myxococcales	28221|Deltaproteobacteria	C	FMN-dependent dehydrogenase	-	-	1.1.3.46	ko:K16422	ko00261,ko01055,ko01130,map00261,map01055,map01130	-	R06633	RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
LZS3_k127_5742440_2	485915.Dret_0280	3.249e-190	599.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2M8SG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_5742440_10	1385510.N781_08765	9.702e-97	334.0	COG2244@1|root,COG2244@2|Bacteria,1TPSH@1239|Firmicutes,4HAGX@91061|Bacilli	91061|Bacilli	S	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid	tuaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03328,ko:K16694,ko:K16695	-	-	-	-	ko00000,ko02000	2.A.66.2,2.A.66.2.6,2.A.66.2.7	-	iYO844.BSU35600	Polysacc_synt_3,Polysacc_synt_C
LZS3_k127_5742440_35	1085623.GNIT_2545	0.00069	52.0	2ES7J@1|root,33JSA@2|Bacteria,1R3KJ@1224|Proteobacteria,1SPCI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
LZS3_k127_5742440_29	56110.Oscil6304_1711	6.077e-26	117.0	COG2227@1|root,COG2227@2|Bacteria,1GQ6N@1117|Cyanobacteria	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_5742440_7	56110.Oscil6304_1708	7.993e-126	414.0	COG0438@1|root,COG0438@2|Bacteria,1G2DD@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_5742440_31	1313421.JHBV01000030_gene2179	1.202e-07	64.0	COG2010@1|root,COG2010@2|Bacteria,4NEEJ@976|Bacteroidetes,1IP2H@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cu2_monoox_C,FlgD_ig
LZS3_k127_5742440_15	1123234.AUKI01000013_gene1581	1.062e-70	257.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
LZS3_k127_5742440_34	211114.JOEF01000019_gene490	0.0002068	53.0	COG0189@1|root,COG2373@1|root,COG4932@1|root,COG0189@2|Bacteria,COG2373@2|Bacteria,COG4932@2|Bacteria,2GIW4@201174|Actinobacteria,4E0EF@85010|Pseudonocardiales	201174|Actinobacteria	M	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,SdrD_B
LZS3_k127_5742440_21	1007103.AFHW01000095_gene3223	7.9e-52	207.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
LZS3_k127_5742440_19	1379698.RBG1_1C00001G0322	3.823e-56	214.0	COG2385@1|root,COG2385@2|Bacteria,2NPRR@2323|unclassified Bacteria	2|Bacteria	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
LZS3_k127_5742440_12	309807.SRU_2425	7.345e-82	286.0	COG2377@1|root,COG2377@2|Bacteria,4NFZU@976|Bacteroidetes,1FIM0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
LZS3_k127_5742440_17	1379698.RBG1_1C00001G0882	9.029e-67	246.0	COG0395@1|root,COG0395@2|Bacteria,2NPFW@2323|unclassified Bacteria	2|Bacteria	U	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
LZS3_k127_5742440_18	521045.Kole_0874	6.348e-61	223.0	COG1175@1|root,COG1175@2|Bacteria,2GC8J@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K17242	ko02010,map02010	M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.39	-	-	BPD_transp_1
LZS3_k127_5742440_9	1379698.RBG1_1C00001G0884	5.145e-97	333.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K02027,ko:K17329	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
LZS3_k127_5742440_11	518766.Rmar_2753	1.277e-88	302.0	COG2103@1|root,COG2103@2|Bacteria,4NEPY@976|Bacteroidetes,1FIKZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
LZS3_k127_5742440_24	573413.Spirs_3120	4.761e-41	166.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	tnp3503b	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	Transposase_mut
LZS3_k127_5742440_30	518766.Rmar_0953	1.577e-25	125.0	COG1572@1|root,COG1572@2|Bacteria,4PIS3@976|Bacteroidetes,1FKDJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
LZS3_k127_5742440_14	861299.J421_2620	1.48e-72	257.0	COG1559@1|root,COG1559@2|Bacteria,1ZTA7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
LZS3_k127_5742440_26	1268072.PSAB_07860	2.416e-33	135.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli,26XDH@186822|Paenibacillaceae	91061|Bacilli	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
LZS3_k127_5742440_22	880073.Calab_1889	5.125e-50	190.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,GAF_3,HATPase_c_2,SSF,SpoIIE
LZS3_k127_5766046_20	1123073.KB899242_gene1157	4.291e-15	76.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1X572@135614|Xanthomonadales	135614|Xanthomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5766046_18	208444.JNYY01000020_gene4533	4.668e-26	118.0	COG2220@1|root,COG2220@2|Bacteria,2GN98@201174|Actinobacteria,4E2GG@85010|Pseudonocardiales	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS3_k127_5766046_10	880073.Calab_1841	7.009e-80	277.0	COG0506@1|root,COG0506@2|Bacteria,2NPED@2323|unclassified Bacteria	2|Bacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
LZS3_k127_5766046_16	420324.KI911943_gene5343	3.048e-57	219.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
LZS3_k127_5766046_8	1320556.AVBP01000012_gene3572	1.526e-99	338.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
LZS3_k127_5766046_14	240015.ACP_1964	2.694e-59	233.0	COG2208@1|root,COG2208@2|Bacteria,3Y4A2@57723|Acidobacteria,2JJ6J@204432|Acidobacteriia	204432|Acidobacteriia	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_3,SpoIIE
LZS3_k127_5766046_22	644281.MFS40622_0758	0.0003204	50.0	COG4818@1|root,arCOG04344@2157|Archaea,2Y0G5@28890|Euryarchaeota,23RV2@183939|Methanococci	183939|Methanococci	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
LZS3_k127_5766046_0	264732.Moth_0568	6.907e-304	953.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,42ER6@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
LZS3_k127_5766046_19	760192.Halhy_0296	1.96e-19	100.0	COG1466@1|root,COG1466@2|Bacteria,4NEIB@976|Bacteroidetes,1IQ3N@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
LZS3_k127_5766046_4	269799.Gmet_0555	7.541e-146	476.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_5766046_17	247490.KSU1_B0686	5.692e-46	189.0	COG3852@1|root,COG3852@2|Bacteria,2J4XY@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_5766046_7	234267.Acid_4641	3.515e-100	341.0	COG1134@1|root,COG1134@2|Bacteria,3Y756@57723|Acidobacteria	57723|Acidobacteria	GM	Wzt C-terminal domain	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
LZS3_k127_5766046_12	192952.MM_0657	5.567e-72	251.0	COG1682@1|root,arCOG04339@2157|Archaea,2Y2VQ@28890|Euryarchaeota,2NA8H@224756|Methanomicrobia	224756|Methanomicrobia	P	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
LZS3_k127_5766046_11	526227.Mesil_1043	6.586e-73	258.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_5766046_5	272134.KB731324_gene1964	2.872e-112	368.0	COG1208@1|root,COG1208@2|Bacteria,1G4AN@1117|Cyanobacteria,1H8TU@1150|Oscillatoriales	1117|Cyanobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
LZS3_k127_5766046_1	118173.KB235914_gene3823	1.05e-181	578.0	COG4310@1|root,COG4310@2|Bacteria,1G39N@1117|Cyanobacteria,1H9B5@1150|Oscillatoriales	1117|Cyanobacteria	S	winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47
LZS3_k127_5766046_13	41431.PCC8801_3332	2.411e-70	246.0	COG1898@1|root,COG1898@2|Bacteria,1G3DC@1117|Cyanobacteria,3KK26@43988|Cyanothece	1117|Cyanobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
LZS3_k127_5766046_2	251229.Chro_2348	2.59e-181	590.0	COG2227@1|root,COG2227@2|Bacteria,1G06X@1117|Cyanobacteria,3VJGG@52604|Pleurocapsales	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
LZS3_k127_5766046_3	357808.RoseRS_2385	2.906e-152	487.0	COG0451@1|root,COG0451@2|Bacteria,2GAMV@200795|Chloroflexi,376SP@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_5766046_6	1095769.CAHF01000010_gene1299	2.076e-111	379.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,2VJ9J@28216|Betaproteobacteria,476WG@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
LZS3_k127_5766046_9	383372.Rcas_3095	1.949e-82	286.0	COG1216@1|root,COG1216@2|Bacteria,2GB2A@200795|Chloroflexi,377SM@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_5766046_15	756272.Plabr_1344	7.348e-58	210.0	COG2148@1|root,COG2148@2|Bacteria,2IX7E@203682|Planctomycetes	203682|Planctomycetes	M	involved in lipopolysaccharide	-	-	-	ko:K03606	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
LZS3_k127_5851326_13	1123242.JH636435_gene833	4.148e-47	192.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
LZS3_k127_5851326_5	648996.Theam_0155	8.806e-110	366.0	COG1060@1|root,COG1060@2|Bacteria,2G3U8@200783|Aquificae	200783|Aquificae	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
LZS3_k127_5851326_2	880073.Calab_1414	1.567e-125	406.0	COG0388@1|root,COG0388@2|Bacteria,2NPKU@2323|unclassified Bacteria	2|Bacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
LZS3_k127_5851326_19	762903.Pedsa_3123	9.982e-30	124.0	COG2259@1|root,COG2259@2|Bacteria,4NTM8@976|Bacteroidetes,1ITB2@117747|Sphingobacteriia	976|Bacteroidetes	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
LZS3_k127_5851326_4	105559.Nwat_2733	2.538e-122	412.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1WWT6@135613|Chromatiales	135613|Chromatiales	M	Surface antigen variable number	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
LZS3_k127_5851326_6	519989.ECTPHS_06762	2.545e-102	374.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1WWU1@135613|Chromatiales	135613|Chromatiales	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
LZS3_k127_5851326_0	1521187.JPIM01000056_gene2609	4.671e-170	539.0	COG1899@1|root,COG1899@2|Bacteria,2G7R7@200795|Chloroflexi,374VZ@32061|Chloroflexia	32061|Chloroflexia	O	PFAM deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
LZS3_k127_5851326_29	686578.AFFX01000009_gene2890	0.0005006	48.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,1RRV4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
LZS3_k127_5851326_26	1191523.MROS_0656	7.477e-09	68.0	28P4Q@1|root,2ZBZV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5851326_9	1237149.C900_05249	1.54e-71	249.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,47PK1@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
LZS3_k127_5851326_15	251221.35214845	5.809e-39	153.0	COG0800@1|root,COG0800@2|Bacteria,1G3B0@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM KDPG and KHG aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
LZS3_k127_5851326_20	459349.CLOAM0984	4.288e-20	107.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
LZS3_k127_5851326_25	1166018.FAES_0417	3.251e-12	68.0	COG4877@1|root,COG4877@2|Bacteria,4NXSU@976|Bacteroidetes,47T6F@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
LZS3_k127_5851326_7	382464.ABSI01000010_gene3212	1.531e-96	323.0	COG0330@1|root,COG0330@2|Bacteria,46USS@74201|Verrucomicrobia,2IVC2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS3_k127_5851326_8	760142.Hipma_0619	1.053e-76	266.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria,2M6W1@213113|Desulfurellales	28221|Deltaproteobacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
LZS3_k127_5851326_14	234267.Acid_3182	4.028e-40	157.0	COG0572@1|root,COG0572@2|Bacteria,3Y4EI@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
LZS3_k127_5851326_3	1125863.JAFN01000001_gene2667	4.681e-123	406.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,42M5V@68525|delta/epsilon subdivisions,2WIR6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	nifS-1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
LZS3_k127_5851326_12	886293.Sinac_1592	1.526e-53	194.0	COG2109@1|root,COG2109@2|Bacteria,2IZYA@203682|Planctomycetes	203682|Planctomycetes	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
LZS3_k127_5851326_24	945713.IALB_2722	1.16e-14	76.0	2EGPU@1|root,33AFZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5851326_11	861299.J421_6340	1.308e-66	237.0	COG1028@1|root,COG1028@2|Bacteria,1ZTIT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
LZS3_k127_5851326_27	944479.JQLX01000013_gene1442	6.352e-07	61.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,HD_5
LZS3_k127_5851326_16	273068.TTE2603	1.827e-38	156.0	COG0726@1|root,COG0726@2|Bacteria,1V2Z7@1239|Firmicutes,25B0R@186801|Clostridia,42G6Y@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Polysaccharide deacetylase	-	-	-	ko:K11931,ko:K21478	ko02026,map02026	-	R03096	RC00010	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1,SLH
LZS3_k127_5851326_28	383381.EH30_01025	1.202e-05	59.0	COG0457@1|root,COG0457@2|Bacteria	383381.EH30_01025|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5851326_1	983917.RGE_05590	2.9e-135	445.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2VK83@28216|Betaproteobacteria,1KMBQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase like family 2	hmsR	-	-	ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
LZS3_k127_5851326_23	459349.CLOAM1790	2.851e-17	95.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
LZS3_k127_5851326_18	72019.SARC_11303T0	6.949e-33	143.0	KOG0379@1|root,KOG4293@1|root,KOG0379@2759|Eukaryota,KOG4293@2759|Eukaryota	2759|Eukaryota	U	DOMON domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B561,Kelch_3,Kelch_4
LZS3_k127_5851326_22	1408473.JHXO01000009_gene3379	2.689e-18	94.0	2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5851326_10	1297742.A176_01859	1.313e-68	250.0	COG3358@1|root,COG3358@2|Bacteria,1RBIA@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
LZS3_k127_5851326_21	1379698.RBG1_1C00001G1559	1.348e-19	104.0	COG0671@1|root,COG0671@2|Bacteria,2NPZH@2323|unclassified Bacteria	2|Bacteria	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF3703,PAP2
LZS3_k127_5851326_17	1283300.ATXB01000002_gene2888	2.794e-38	155.0	2DP87@1|root,330Z8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5933316_16	886379.AEWI01000043_gene3295	1.928e-113	378.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,3XIJ3@558415|Marinilabiliaceae	976|Bacteroidetes	G	PEP-utilising enzyme, mobile domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
LZS3_k127_5933316_3	1337936.IJ00_25065	3.798e-200	637.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,1HMNK@1161|Nostocales	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135,ko:K22187	ko00010,ko00040,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00040,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146,R11768	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
LZS3_k127_5933316_52	880073.Calab_1777	1.007e-14	87.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.2.1.99	ko:K06113,ko:K12685	-	-	-	-	ko00000,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Cu_amine_oxidN1,Peptidase_S8,SLH
LZS3_k127_5933316_47	880073.Calab_0921	2.103e-24	121.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_5933316_11	760568.Desku_2618	5.504e-134	455.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,2608I@186807|Peptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
LZS3_k127_5933316_12	767817.Desgi_1364	3.58e-127	414.0	COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,24AU0@186801|Clostridia,2604H@186807|Peptococcaceae	186801|Clostridia	J	PFAM glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
LZS3_k127_5933316_60	585531.HMPREF0063_11228	2.642e-06	58.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,4DP6A@85009|Propionibacteriales	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
LZS3_k127_5933316_22	880073.Calab_2041	1.631e-96	332.0	COG2239@1|root,COG2239@2|Bacteria,2NP6V@2323|unclassified Bacteria	2|Bacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N,PRC
LZS3_k127_5933316_33	665571.STHERM_c09770	3.879e-56	212.0	COG1253@1|root,COG1253@2|Bacteria,2J61P@203691|Spirochaetes	203691|Spirochaetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
LZS3_k127_5933316_49	1121033.AUCF01000003_gene3436	9.298e-23	104.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,2JSNN@204441|Rhodospirillales	204441|Rhodospirillales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
LZS3_k127_5933316_23	880073.Calab_2813	4.901e-95	341.0	COG1480@1|root,COG1480@2|Bacteria,2NP1K@2323|unclassified Bacteria	2|Bacteria	S	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
LZS3_k127_5933316_25	644966.Tmar_2172	3.494e-93	318.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3WCEH@538999|Clostridiales incertae sedis	186801|Clostridia	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
LZS3_k127_5933316_55	648996.Theam_0751	2.162e-10	71.0	COG1652@1|root,COG2433@1|root,COG1652@2|Bacteria,COG2433@2|Bacteria,2G4TM@200783|Aquificae	200783|Aquificae	S	PFAM Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
LZS3_k127_5933316_6	580331.Thit_1032	6.063e-175	569.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,42EM9@68295|Thermoanaerobacterales	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
LZS3_k127_5933316_17	251229.Chro_1406	1.783e-104	353.0	COG0124@1|root,COG0124@2|Bacteria,1G066@1117|Cyanobacteria,3VI73@52604|Pleurocapsales	1117|Cyanobacteria	J	tRNA synthetase class II core domain (G, H, P, S and T)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
LZS3_k127_5933316_53	290397.Adeh_2354	1.247e-13	76.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
LZS3_k127_5933316_48	1234664.AMRO01000003_gene714	6.497e-23	104.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1WEX0@129337|Geobacillus	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	fruA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
LZS3_k127_5933316_57	1196323.ALKF01000114_gene4988	1.094e-07	63.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli,26RPS@186822|Paenibacillaceae	91061|Bacilli	S	Protein conserved in bacteria	ybbR	GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009	-	-	-	-	-	-	-	-	-	-	YbbR
LZS3_k127_5933316_32	765910.MARPU_07215	8.871e-57	215.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1WX8Q@135613|Chromatiales	135613|Chromatiales	M	Cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
LZS3_k127_5933316_35	644282.Deba_2866	5.913e-50	190.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS3_k127_5933316_20	1379698.RBG1_1C00001G0598	2.861e-100	335.0	COG0568@1|root,COG0568@2|Bacteria,2NNY9@2323|unclassified Bacteria	2|Bacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_5933316_21	1499967.BAYZ01000195_gene3087	1.557e-96	336.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	htrA	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
LZS3_k127_5933316_44	1379698.RBG1_1C00001G0342	2.447e-35	148.0	COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
LZS3_k127_5933316_42	1379698.RBG1_1C00001G0490	5.304e-38	159.0	COG2067@1|root,COG2067@2|Bacteria,2NR8A@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5933316_58	1254432.SCE1572_34500	7.277e-07	63.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
LZS3_k127_5933316_40	459349.CLOAM0575	1.41e-39	171.0	COG4412@1|root,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CarboxypepD_reg,FlgD_ig,Peptidase_M6
LZS3_k127_5933316_64	1379698.RBG1_1C00001G1235	0.000408	52.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
LZS3_k127_5933316_37	1379698.RBG1_1C00001G1236	1.62e-45	175.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	fn3
LZS3_k127_5933316_27	459349.CLOAM1546	8.163e-76	287.0	COG0457@1|root,COG3604@1|root,COG0457@2|Bacteria,COG3604@2|Bacteria	2|Bacteria	KT	transcription factor binding	nifA	-	-	ko:K02584,ko:K11914	ko02020,map02020	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
LZS3_k127_5933316_10	269799.Gmet_0776	4.105e-149	484.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,43TKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_5933316_29	1379698.RBG1_1C00001G1097	2.336e-74	278.0	COG0820@1|root,COG0820@2|Bacteria,2NP4V@2323|unclassified Bacteria	2|Bacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
LZS3_k127_5933316_56	880073.Calab_0035	3.369e-10	72.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FlgD_ig,SLH
LZS3_k127_5933316_54	656519.Halsa_0414	3.861e-12	79.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,24F0X@186801|Clostridia,3WAA6@53433|Halanaerobiales	186801|Clostridia	M	PFAM Surface antigen variable number repeat	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS3_k127_5933316_63	485913.Krac_12034	0.0003892	52.0	COG1664@1|root,COG1664@2|Bacteria,2G7EZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS3_k127_5933316_65	649831.L083_7134	0.0006047	49.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4DDUI@85008|Micromonosporales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
LZS3_k127_5933316_51	765420.OSCT_0654	1.358e-17	95.0	COG3595@1|root,COG3595@2|Bacteria,2G9KA@200795|Chloroflexi,377P5@32061|Chloroflexia	32061|Chloroflexia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
LZS3_k127_5933316_34	880073.Calab_1183	7.074e-54	197.0	COG1595@1|root,COG1595@2|Bacteria,2NPRC@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_5933316_5	696369.KI912183_gene1958	1.639e-184	586.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,2600A@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
LZS3_k127_5933316_61	330214.NIDE2912	5.747e-06	59.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	ftsB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
LZS3_k127_5933316_59	1229780.BN381_130143	1.445e-06	51.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5933316_24	373903.Hore_13580	1.443e-94	327.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
LZS3_k127_5933316_7	316274.Haur_1713	3.369e-163	527.0	COG2070@1|root,COG2070@2|Bacteria,2G78C@200795|Chloroflexi,376A6@32061|Chloroflexia	32061|Chloroflexia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
LZS3_k127_5933316_45	1173263.Syn7502_03178	2.991e-29	123.0	28KW4@1|root,2ZACH@2|Bacteria,1G2SE@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5933316_38	349521.HCH_05597	5.55e-45	168.0	COG3795@1|root,COG3795@2|Bacteria,1N32U@1224|Proteobacteria,1S82G@1236|Gammaproteobacteria,1XKS3@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YCII
LZS3_k127_5933316_4	479434.Sthe_2955	4.5e-187	594.0	COG4941@1|root,COG4941@2|Bacteria,2G84R@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_5933316_2	945713.IALB_0301	6.968e-234	730.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdhA	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
LZS3_k127_5933316_0	880073.Calab_2714	0.0	1027.0	COG0574@1|root,COG0784@1|root,COG0574@2|Bacteria,COG0784@2|Bacteria,2NQKM@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N,Response_reg,SpoIIE
LZS3_k127_5933316_46	234267.Acid_4208	3.321e-28	121.0	COG1913@1|root,COG1913@2|Bacteria,3Y880@57723|Acidobacteria	57723|Acidobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
LZS3_k127_5933316_9	945713.IALB_2429	6.899e-154	503.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_5933316_15	234267.Acid_4206	4.229e-116	395.0	COG4191@1|root,COG4191@2|Bacteria,3Y42C@57723|Acidobacteria	57723|Acidobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS3_k127_5933316_14	234267.Acid_4205	1.883e-126	416.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
LZS3_k127_5933316_26	1121920.AUAU01000012_gene2649	2.513e-82	281.0	COG0437@1|root,COG0437@2|Bacteria,3Y5RE@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
LZS3_k127_5933316_36	204669.Acid345_0767	3.167e-46	176.0	COG0509@1|root,COG0509@2|Bacteria,3Y7RS@57723|Acidobacteria	57723|Acidobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
LZS3_k127_5933316_43	1279009.ADICEAN_03991	1.755e-35	148.0	COG5624@1|root,COG5624@2|Bacteria,4NZQQ@976|Bacteroidetes	976|Bacteroidetes	K	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5933316_50	945713.IALB_0843	1.096e-19	102.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9,Laminin_G_3
LZS3_k127_5933316_41	426117.M446_6628	1.769e-39	159.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,1JSKK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
LZS3_k127_5933316_31	945713.IALB_0515	7.179e-64	228.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_5933316_18	880073.Calab_1105	5.085e-104	383.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713,ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.33.1	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Peptidase_S8,Pkinase,VCBS
LZS3_k127_5933316_13	945713.IALB_2155	7.783e-127	422.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepD	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	iPC815.YPO3230,iSBO_1134.SBO_0243	M20_dimer,Peptidase_M20
LZS3_k127_5933316_8	1499967.BAYZ01000152_gene1435	7.893e-158	509.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
LZS3_k127_5933316_19	1254432.SCE1572_20525	1.092e-100	359.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_5933316_1	385682.AFSL01000102_gene55	8.926e-293	915.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae	976|Bacteroidetes	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
LZS3_k127_5933316_28	945713.IALB_0509	1.559e-74	265.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
LZS3_k127_5933316_30	383372.Rcas_3322	1.573e-71	248.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
LZS3_k127_5969187_3	251221.35211383	1.992e-55	212.0	COG3975@1|root,COG3975@2|Bacteria	2|Bacteria	-	-	spoIVB	-	3.4.21.116,3.4.24.3	ko:K01387,ko:K06399	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	Peptidase_M61,Peptidase_M9,Peptidase_M9_N
LZS3_k127_5969187_8	1173021.ALWA01000019_gene386	3.643e-16	91.0	COG3420@1|root,COG3420@2|Bacteria,1G2FG@1117|Cyanobacteria	1117|Cyanobacteria	P	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1565,SLH
LZS3_k127_5969187_6	945713.IALB_2396	8.319e-18	100.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
LZS3_k127_5969187_1	331678.Cphamn1_1670	9.785e-93	318.0	COG1397@1|root,COG1397@2|Bacteria	2|Bacteria	O	ADP-ribosylglycohydrolase	draG	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,Inositol_P
LZS3_k127_5969187_4	644966.Tmar_1540	1.215e-42	171.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia	186801|Clostridia	L	COG3547, transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
LZS3_k127_5969187_7	880073.Calab_0921	2.808e-16	94.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_5969187_5	1379698.RBG1_1C00001G1831	4.749e-29	136.0	COG2706@1|root,COG4733@1|root,COG2706@2|Bacteria,COG4733@2|Bacteria,2NR81@2323|unclassified Bacteria	2|Bacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	PKD,VCBS
LZS3_k127_5969187_2	1192034.CAP_2122	6.481e-82	302.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_5969187_0	1089550.ATTH01000001_gene1829	4.322e-119	403.0	28HH2@1|root,2Z7ST@2|Bacteria,4NMWR@976|Bacteroidetes	976|Bacteroidetes	M	Thiol-activated cytolysin	-	-	-	ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	Thiol_cytolysin
LZS3_k127_5969187_9	234267.Acid_6256	9.097e-07	61.0	COG4447@1|root,COG4447@2|Bacteria,3Y9AF@57723|Acidobacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,SBBP,Sortilin-Vps10
LZS3_k127_5969187_10	1313421.JHBV01000075_gene13	3.766e-05	56.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Gram_pos_anchor
LZS3_k127_6013461_16	1168289.AJKI01000044_gene16	1.591e-22	102.0	COG2978@1|root,COG2978@2|Bacteria,4NH64@976|Bacteroidetes,2FMI9@200643|Bacteroidia,3XKCR@558415|Marinilabiliaceae	976|Bacteroidetes	H	AbgT putative transporter family	ydaH	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
LZS3_k127_6013461_5	247490.KSU1_C0449	9.324e-77	287.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_6013461_18	1379698.RBG1_1C00001G0581	5.697e-14	86.0	COG2911@1|root,COG2911@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Cohesin,FlgD_ig,Peptidase_S74
LZS3_k127_6013461_13	443598.AUFA01000017_gene7352	1.171e-30	125.0	2A6EI@1|root,30V7D@2|Bacteria,1R7V1@1224|Proteobacteria,2U338@28211|Alphaproteobacteria,3JW4K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6013461_12	1183438.GKIL_0980	1.66e-42	159.0	COG4319@1|root,COG4319@2|Bacteria,1GFSM@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
LZS3_k127_6013461_11	1237149.C900_05615	4.886e-43	161.0	COG1846@1|root,COG1846@2|Bacteria,4NQ5T@976|Bacteroidetes,47QE6@768503|Cytophagia	976|Bacteroidetes	K	transcriptional regulator	slyA	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
LZS3_k127_6013461_14	1408422.JHYF01000004_gene1573	2.664e-30	124.0	COG1765@1|root,COG1765@2|Bacteria,1VXQ3@1239|Firmicutes,252K3@186801|Clostridia	186801|Clostridia	O	OsmC-like protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
LZS3_k127_6013461_0	345341.KUTG_04234	2.02e-163	521.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
LZS3_k127_6013461_7	1192034.CAP_2122	8.07e-75	283.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_6013461_17	880073.Calab_0921	4.948e-14	87.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_6013461_2	227377.CBU_2024	1.544e-126	411.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1JCEE@118969|Legionellales	118969|Legionellales	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_6013461_3	1341181.FLJC2902T_22260	3.479e-93	317.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,1I1KX@117743|Flavobacteriia,2NWM3@237|Flavobacterium	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
LZS3_k127_6013461_15	1545915.JROG01000009_gene2862	5.979e-29	123.0	COG1695@1|root,COG1695@2|Bacteria,1PCI9@1224|Proteobacteria,2V1YM@28211|Alphaproteobacteria,2KC7X@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
LZS3_k127_6013461_20	1156937.MFUM_990004	3.82e-08	66.0	COG3577@1|root,COG3577@2|Bacteria,46ZCQ@74201|Verrucomicrobia,37H8W@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
LZS3_k127_6013461_6	204669.Acid345_3013	7.303e-75	262.0	COG0395@1|root,COG0395@2|Bacteria,3Y7HR@57723|Acidobacteria	57723|Acidobacteria	G	Inward rectifier potassium channel	-	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
LZS3_k127_6013461_4	118168.MC7420_5234	9.256e-85	317.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6013461_19	1089550.ATTH01000001_gene812	1.442e-13	85.0	COG1361@1|root,COG4412@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K07004,ko:K09955,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Laminin_G_3
LZS3_k127_6013461_1	1089550.ATTH01000001_gene1831	1.364e-127	443.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
LZS3_k127_6013461_9	1183438.GKIL_3942	1.191e-52	192.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
LZS3_k127_6013461_10	1237500.ANBA01000009_gene1390	3.291e-45	167.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria,4EQ8P@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	ywzG	-	-	-	-	-	-	-	-	-	-	-	PadR
LZS3_k127_6013461_8	1267535.KB906767_gene1934	3.26e-67	240.0	2CA5R@1|root,2Z81H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
LZS3_k127_6050632_1	234267.Acid_0921	1.064e-228	721.0	COG3581@1|root,COG3581@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6050632_2	1120797.KB908260_gene4073	2.899e-153	522.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	pknK_2	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12
LZS3_k127_6050632_3	880073.Calab_0921	9.012e-22	112.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_6050632_0	234267.Acid_0922	2.493e-301	936.0	COG1924@1|root,COG3580@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,3Y7VB@57723|Acidobacteria	57723|Acidobacteria	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
LZS3_k127_6059311_2	927658.AJUM01000037_gene1831	2.24e-159	513.0	COG2978@1|root,COG2978@2|Bacteria,4NH64@976|Bacteroidetes,2FMI9@200643|Bacteroidia,3XKCR@558415|Marinilabiliaceae	976|Bacteroidetes	H	AbgT putative transporter family	ydaH	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
LZS3_k127_6059311_0	926549.KI421517_gene2980	8.804e-237	758.0	COG2120@1|root,COG2120@2|Bacteria,4NE9K@976|Bacteroidetes,47KXK@768503|Cytophagia	976|Bacteroidetes	G	PFAM GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
LZS3_k127_6059311_1	1047013.AQSP01000125_gene2632	1.578e-192	623.0	COG0591@1|root,COG0591@2|Bacteria,2NR0M@2323|unclassified Bacteria	2|Bacteria	E	Sodium:solute symporter family	yidK	-	-	-	-	-	-	-	-	-	-	-	SSF
LZS3_k127_6059311_3	215803.DB30_4215	7.755e-08	59.0	COG0457@1|root,COG0457@2|Bacteria,1Q3NI@1224|Proteobacteria,43422@68525|delta/epsilon subdivisions,2X4RF@28221|Deltaproteobacteria,2YZFW@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
LZS3_k127_6073107_1	215803.DB30_3249	1.014e-46	172.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
LZS3_k127_6073107_2	1140.Synpcc7942_1819	1.229e-43	165.0	COG0262@1|root,COG0262@2|Bacteria,1G6PW@1117|Cyanobacteria,1H3FB@1129|Synechococcus	1117|Cyanobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
LZS3_k127_6073107_0	1380393.JHVP01000008_gene4712	4.344e-52	194.0	COG0500@1|root,COG2226@2|Bacteria,2I7XP@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS3_k127_6073107_4	325777.GW15_0208390	1.861e-28	126.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1X5YF@135614|Xanthomonadales	135614|Xanthomonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
LZS3_k127_6073107_7	1173027.Mic7113_0608	1.045e-05	59.0	COG0810@1|root,COG0810@2|Bacteria,1G475@1117|Cyanobacteria,1HANZ@1150|Oscillatoriales	1117|Cyanobacteria	M	von Willebrand factor type D domain	-	-	-	-	-	-	-	-	-	-	-	-	RGM_C,VWD
LZS3_k127_6073107_3	1121875.KB907549_gene1775	1.598e-38	145.0	COG0790@1|root,COG0790@2|Bacteria,4NMCC@976|Bacteroidetes,1I498@117743|Flavobacteriia	976|Bacteroidetes	KLT	Sel1 repeat protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Pkinase,Sel1
LZS3_k127_6146739_9	290397.Adeh_4042	2.216e-21	105.0	COG1403@1|root,COG1403@2|Bacteria,1P9DV@1224|Proteobacteria,432XA@68525|delta/epsilon subdivisions,2WXXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS3_k127_6146739_0	945713.IALB_2718	2.179e-230	720.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
LZS3_k127_6146739_3	760568.Desku_2838	1.664e-97	343.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
LZS3_k127_6146739_8	880073.Calab_3296	5.719e-22	110.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
LZS3_k127_6146739_13	1123278.KB893445_gene1153	1.747e-09	72.0	COG1577@1|root,COG1874@1|root,COG2374@1|root,COG3210@1|root,COG4625@1|root,COG4886@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG2374@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	mvaK2	-	2.7.1.36,2.7.4.2,3.1.3.5,3.2.1.97,3.4.21.72,4.2.2.23	ko:K00869,ko:K00938,ko:K01081,ko:K01347,ko:K07004,ko:K17624,ko:K18195,ko:K21449	ko00230,ko00240,ko00760,ko00900,ko01100,ko01110,ko01130,ko04146,map00230,map00240,map00760,map00900,map01100,map01110,map01130,map04146	M00095	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02245,R02323,R02719,R03245,R03346	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko02044	1.B.12.3,1.B.40.2	GH101,PL4	-	CBM-like,GHMP_kinases_C,GHMP_kinases_N,HtaA,NPCBM,RhgB_N,fn3_3
LZS3_k127_6146739_14	512565.AMIS_42840	1.726e-06	62.0	28HJF@1|root,2Z7UK@2|Bacteria,2ICK7@201174|Actinobacteria,4DAVB@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6146739_11	84531.JMTZ01000001_gene2271	1.459e-11	77.0	COG3291@1|root,COG3420@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.11.10,3.4.21.50,3.4.24.25,3.4.24.3	ko:K01337,ko:K01387,ko:K05994,ko:K08604,ko:K14645,ko:K20276	ko02024,ko05110,ko05111,map02024,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Inhibitor_I9,LVIVD,PKD,P_proprotein,Peptidase_M14,Peptidase_S8
LZS3_k127_6146739_4	1278073.MYSTI_05368	1.771e-93	312.0	COG0702@1|root,COG0702@2|Bacteria,1R8B9@1224|Proteobacteria	1224|Proteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
LZS3_k127_6146739_2	1123073.KB899243_gene775	3.979e-100	329.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,1S2TQ@1236|Gammaproteobacteria,1X4M1@135614|Xanthomonadales	135614|Xanthomonadales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
LZS3_k127_6146739_1	1144275.COCOR_06356	1.416e-143	465.0	COG1680@1|root,COG1680@2|Bacteria,1R4P6@1224|Proteobacteria	1224|Proteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
LZS3_k127_6146739_12	1502850.FG91_00796	7.764e-11	73.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1R5P1@1224|Proteobacteria,2U0ZV@28211|Alphaproteobacteria,2KEB5@204457|Sphingomonadales	204457|Sphingomonadales	QU	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
LZS3_k127_6146739_7	1343739.PAP_03130	1.189e-31	141.0	COG1011@1|root,arCOG02291@2157|Archaea,2XTX3@28890|Euryarchaeota,243KR@183968|Thermococci	183968|Thermococci	S	Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
LZS3_k127_6146739_10	331678.Cphamn1_0393	4.101e-17	91.0	COG1266@1|root,COG1266@2|Bacteria,1FE3B@1090|Chlorobi	1090|Chlorobi	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
LZS3_k127_6146739_5	518766.Rmar_0744	3.774e-37	160.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1FKAM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
LZS3_k127_6251845_24	330214.NIDE3014	1.164e-61	222.0	COG1091@1|root,COG1091@2|Bacteria,3J0SU@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
LZS3_k127_6251845_23	1041930.Mtc_0198	1.584e-63	230.0	COG1216@1|root,arCOG01383@2157|Archaea,2XUCM@28890|Euryarchaeota,2NAQ3@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
LZS3_k127_6251845_21	335543.Sfum_0219	1.02e-67	257.0	COG0457@1|root,COG3118@1|root,COG3379@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2MRX9@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_6251845_5	479434.Sthe_1664	8.467e-165	546.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi,27Y1N@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
LZS3_k127_6251845_34	278963.ATWD01000001_gene2778	6.907e-05	55.0	COG1807@1|root,COG1807@2|Bacteria,3Y46U@57723|Acidobacteria,2JIQH@204432|Acidobacteriia	204432|Acidobacteriia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_6251845_10	1298858.AUEL01000014_gene616	3.142e-122	402.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,43N46@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
LZS3_k127_6251845_11	1379698.RBG1_1C00001G0505	3.366e-121	425.0	COG0308@1|root,COG0308@2|Bacteria,2NPPZ@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M1 domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
LZS3_k127_6251845_6	1125863.JAFN01000001_gene1446	1.495e-141	467.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6251845_22	269799.Gmet_2454	2.075e-64	234.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43C4K@68525|delta/epsilon subdivisions,2X7F1@28221|Deltaproteobacteria,43TX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
LZS3_k127_6251845_31	1397527.Q670_01420	7.152e-19	94.0	COG4719@1|root,COG4719@2|Bacteria,1N3PM@1224|Proteobacteria,1SF72@1236|Gammaproteobacteria,1XQB1@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS3_k127_6251845_12	1330700.JQNC01000003_gene722	6.485e-114	400.0	COG1470@1|root,COG4719@1|root,COG1470@2|Bacteria,COG4719@2|Bacteria,1WJNZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS3_k127_6251845_32	1121937.AUHJ01000004_gene1114	2.69e-15	92.0	COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,1S4WV@1236|Gammaproteobacteria,46AXB@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
LZS3_k127_6251845_26	443144.GM21_1522	1.37e-56	229.0	COG1361@1|root,COG2885@1|root,COG4719@1|root,COG1361@2|Bacteria,COG2885@2|Bacteria,COG4719@2|Bacteria,1QW22@1224|Proteobacteria	1224|Proteobacteria	M	Ompa motb domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,OmpA,SdrD_B
LZS3_k127_6251845_33	985665.HPL003_04460	3.173e-05	58.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,26QKX@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
LZS3_k127_6251845_2	880073.Calab_1551	1.553e-229	721.0	COG1866@1|root,COG1866@2|Bacteria,2NQI3@2323|unclassified Bacteria	2|Bacteria	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
LZS3_k127_6251845_28	1142394.PSMK_17130	1.757e-52	199.0	COG1018@1|root,COG1018@2|Bacteria,2IXKZ@203682|Planctomycetes	203682|Planctomycetes	C	Oxidoreductase NAD-binding domain	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	NAD_binding_1
LZS3_k127_6251845_0	945713.IALB_2978	0.0	1257.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
LZS3_k127_6251845_29	880073.Calab_1748	2.196e-44	167.0	COG2010@1|root,COG2010@2|Bacteria,2NR69@2323|unclassified Bacteria	2|Bacteria	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
LZS3_k127_6251845_8	879212.DespoDRAFT_03479	5.048e-131	429.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,2MJ9S@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
LZS3_k127_6251845_25	247490.KSU1_B0456	3.011e-59	208.0	COG0698@1|root,COG0698@2|Bacteria,2IZSB@203682|Planctomycetes	203682|Planctomycetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
LZS3_k127_6251845_7	472759.Nhal_2901	1.425e-137	451.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	135613|Chromatiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS3_k127_6251845_3	105559.Nwat_1144	3.827e-188	599.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
LZS3_k127_6251845_9	1408473.JHXO01000008_gene2655	6.121e-123	400.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
LZS3_k127_6251845_14	330214.NIDE2700	5.161e-103	349.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wbpT	-	-	ko:K13003	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_6251845_15	649638.Trad_0736	4.244e-102	346.0	COG0438@1|root,COG0438@2|Bacteria,1WJTX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_6251845_19	935845.JADQ01000016_gene3638	1.598e-82	286.0	COG0438@1|root,COG0438@2|Bacteria,1U0P3@1239|Firmicutes,4IA3X@91061|Bacilli,272BY@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4
LZS3_k127_6251845_1	1125863.JAFN01000001_gene912	0.0	1047.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS3_k127_6251845_17	1161401.ASJA01000006_gene1887	1.311e-89	312.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,2VF2W@28211|Alphaproteobacteria,43WSP@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
LZS3_k127_6251845_18	697282.Mettu_2305	3.022e-85	308.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMP5@1236|Gammaproteobacteria,1XER7@135618|Methylococcales	135618|Methylococcales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_6251845_30	234267.Acid_5986	8.951e-37	146.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	psrA	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_6251845_35	1305737.JAFX01000001_gene1392	0.0002856	53.0	COG3391@1|root,COG3391@2|Bacteria,4NNMZ@976|Bacteroidetes	976|Bacteroidetes	S	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128
LZS3_k127_6251845_27	945713.IALB_0694	1.338e-53	207.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
LZS3_k127_6251845_4	1047013.AQSP01000079_gene2041	7.469e-182	606.0	COG0841@1|root,COG0841@2|Bacteria,2NQI6@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	mdtC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_6251845_13	880073.Calab_1701	8.792e-111	401.0	COG0841@1|root,COG0841@2|Bacteria,2NQF8@2323|unclassified Bacteria	2|Bacteria	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
LZS3_k127_6251845_16	448385.sce3387	8.522e-102	357.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6251845_20	1123242.JH636435_gene2836	1.659e-77	274.0	COG4398@1|root,COG4398@2|Bacteria,2IXYT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
LZS3_k127_6328615_4	1379698.RBG1_1C00001G1831	1.175e-17	97.0	COG2706@1|root,COG4733@1|root,COG2706@2|Bacteria,COG4733@2|Bacteria,2NR81@2323|unclassified Bacteria	2|Bacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	PKD,VCBS
LZS3_k127_6328615_0	1192034.CAP_3762	1.536e-91	323.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2YZYM@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_6328615_3	880073.Calab_0921	4.233e-18	100.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_6328615_2	1192034.CAP_2122	5.595e-81	302.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_6328615_1	1279017.AQYJ01000028_gene2047	2.298e-91	318.0	COG0265@1|root,COG0265@2|Bacteria,1PI1V@1224|Proteobacteria,1S3H8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,SidE,Trypsin_2
LZS3_k127_6348738_18	1286632.P278_15970	2.58e-11	72.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
LZS3_k127_6348738_15	880073.Calab_0041	1.385e-19	102.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
LZS3_k127_6348738_7	1123234.AUKI01000013_gene1581	1.257e-57	218.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
LZS3_k127_6348738_1	1519464.HY22_05590	5.217e-233	752.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
LZS3_k127_6348738_17	452637.Oter_0581	5.874e-13	79.0	COG3595@1|root,COG3595@2|Bacteria,46W9C@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6348738_10	1047013.AQSP01000111_gene1689	7.923e-38	153.0	COG1595@1|root,COG1595@2|Bacteria,2NPR9@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_6348738_21	525904.Tter_0952	8.644e-05	55.0	COG1413@1|root,COG1413@2|Bacteria,2NR83@2323|unclassified Bacteria	2|Bacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
LZS3_k127_6348738_0	1123257.AUFV01000009_gene2282	8.267e-290	906.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1X4N0@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
LZS3_k127_6348738_20	314285.KT71_02912	1.261e-05	54.0	2EFI3@1|root,339AJ@2|Bacteria,1N96F@1224|Proteobacteria,1SE0P@1236|Gammaproteobacteria,1J9XG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
LZS3_k127_6348738_19	234267.Acid_3708	3.143e-07	61.0	2DKN8@1|root,3191E@2|Bacteria,3Y4VE@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6348738_12	1089550.ATTH01000001_gene2333	6.576e-29	122.0	COG1595@1|root,COG1595@2|Bacteria,4PF4G@976|Bacteroidetes,1FK4D@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_6348738_16	394221.Mmar10_0567	1.761e-14	83.0	COG2220@1|root,COG2220@2|Bacteria,1RKSI@1224|Proteobacteria,2UNK6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS3_k127_6348738_6	1166018.FAES_4360	8.55e-66	232.0	28IIU@1|root,2Z8JV@2|Bacteria,4NEFH@976|Bacteroidetes,47JU3@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6348738_9	641524.ADICYQ_0706	6.404e-40	161.0	COG3391@1|root,COG4409@1|root,COG3391@2|Bacteria,COG4409@2|Bacteria,4NX00@976|Bacteroidetes	976|Bacteroidetes	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
LZS3_k127_6348738_22	1120983.KB894570_gene1658	0.0002712	52.0	2BCV0@1|root,326FP@2|Bacteria,1MYXP@1224|Proteobacteria,2U5PU@28211|Alphaproteobacteria,1JPI0@119043|Rhodobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	ko:K20326	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Phenol_MetA_deg
LZS3_k127_6348738_11	886377.Murru_1459	6.275e-32	128.0	COG0316@1|root,COG0316@2|Bacteria,4NQC8@976|Bacteroidetes,1I2SJ@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the HesB IscA family	sufA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
LZS3_k127_6348738_5	344747.PM8797T_30781	1.186e-100	331.0	COG0605@1|root,COG0605@2|Bacteria,2IX16@203682|Planctomycetes	203682|Planctomycetes	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
LZS3_k127_6348738_8	266117.Rxyl_2043	6.075e-41	153.0	COG2154@1|root,COG2154@2|Bacteria,2HPFQ@201174|Actinobacteria,4CQU3@84995|Rubrobacteria	84995|Rubrobacteria	H	Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
LZS3_k127_6348738_13	391625.PPSIR1_41114	1.209e-25	113.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42U5E@68525|delta/epsilon subdivisions,2WSV3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	thioesterase	-	-	3.1.2.28	ko:K07107,ko:K12073	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
LZS3_k127_6348738_4	1455608.JDTH01000001_gene3467	3.473e-109	363.0	COG0604@1|root,arCOG01458@2157|Archaea,2XU0Q@28890|Euryarchaeota,23SPC@183963|Halobacteria	183963|Halobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor1	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_6348738_2	1254432.SCE1572_07650	1.201e-198	632.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,4388N@68525|delta/epsilon subdivisions,2XA2D@28221|Deltaproteobacteria,2YW7N@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
LZS3_k127_6348738_3	502025.Hoch_5225	5.328e-133	432.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,437U1@68525|delta/epsilon subdivisions,2X33K@28221|Deltaproteobacteria,2YU2K@29|Myxococcales	28221|Deltaproteobacteria	S	benzoyl-CoA oxygenase	-	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
LZS3_k127_6386975_0	1499967.BAYZ01000026_gene1569	8.257e-273	851.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS3_k127_6386975_8	1379698.RBG1_1C00001G0474	4.524e-102	348.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
LZS3_k127_6386975_24	349102.Rsph17025_0745	2.514e-08	65.0	COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,2TTDM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS3_k127_6386975_20	373903.Hore_22330	1.707e-15	79.0	2DG7P@1|root,2ZUUE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6386975_5	370438.PTH_0241	6.054e-137	449.0	COG2046@1|root,COG2046@2|Bacteria,1TR4C@1239|Firmicutes,249ZJ@186801|Clostridia,26026@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
LZS3_k127_6386975_4	886293.Sinac_5883	1.2e-150	500.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_6386975_14	525904.Tter_0038	1.338e-70	244.0	COG0529@1|root,COG0529@2|Bacteria,2NPBJ@2323|unclassified Bacteria	2|Bacteria	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4	ko:K00390,ko:K00860,ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R02021,R04928,R04929	RC00002,RC00007,RC00078,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
LZS3_k127_6386975_7	1047013.AQSP01000067_gene2199	7.275e-109	369.0	COG3379@1|root,COG3379@2|Bacteria,2NQEW@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_6386975_1	234267.Acid_6181	7.1e-188	609.0	COG3379@1|root,COG3379@2|Bacteria,3Y7EC@57723|Acidobacteria	57723|Acidobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_6386975_2	1047013.AQSP01000067_gene2201	1.114e-168	553.0	COG3379@1|root,COG3379@2|Bacteria,2NQIG@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_6386975_26	1499967.BAYZ01000008_gene5412	0.0003121	52.0	2EQW9@1|root,33IG2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6386975_19	234267.Acid_6179	2.159e-16	89.0	2DZX2@1|root,32VM6@2|Bacteria,3Y88Y@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6386975_10	1267533.KB906734_gene3701	1.101e-97	334.0	COG4690@1|root,COG4690@2|Bacteria,3Y8TZ@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
LZS3_k127_6386975_9	671143.DAMO_1543	5.621e-99	338.0	COG2379@1|root,COG2379@2|Bacteria,2NNQP@2323|unclassified Bacteria	2|Bacteria	G	MOFRL family	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
LZS3_k127_6386975_23	1089550.ATTH01000001_gene1148	1.965e-08	68.0	COG1523@1|root,COG4733@1|root,COG1523@2|Bacteria,COG4733@2|Bacteria,4NHA4@976|Bacteroidetes,1FIRB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48,FlgD_ig
LZS3_k127_6386975_15	234267.Acid_6287	1.539e-58	228.0	COG1404@1|root,COG1470@1|root,COG3506@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,COG3506@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF1349)	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF11,DUF1349,Peptidase_S8,fn3
LZS3_k127_6386975_22	234831.PSM_A1644	4.449e-11	76.0	COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S1N2@1236|Gammaproteobacteria,2Q1I9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
LZS3_k127_6386975_21	497965.Cyan7822_5116	2.916e-14	85.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1GC1J@1117|Cyanobacteria,3KJVM@43988|Cyanothece	1117|Cyanobacteria	QU	Polymorphic membrane protein Chlamydia	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin
LZS3_k127_6386975_3	880073.Calab_1714	6.724e-165	537.0	COG2866@1|root,COG2866@2|Bacteria,2NQT6@2323|unclassified Bacteria	2|Bacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
LZS3_k127_6386975_18	448385.sce3068	6.003e-51	189.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,42PEY@68525|delta/epsilon subdivisions,2WJJ3@28221|Deltaproteobacteria,2YUIV@29|Myxococcales	28221|Deltaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_6386975_13	861299.J421_2451	5.798e-88	304.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_6386975_6	404589.Anae109_4174	1.081e-125	438.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,43AQI@68525|delta/epsilon subdivisions,2X64F@28221|Deltaproteobacteria	1224|Proteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
LZS3_k127_6386975_12	1379698.RBG1_1C00001G0520	3.307e-89	312.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	CHASE2,GAF,GAF_2,HATPase_c_2,SpoIIE
LZS3_k127_6386975_25	1033802.SSPSH_003178	1.003e-05	54.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Secondary thiamine-phosphate synthase enzyme	yjbQ	-	-	-	-	-	-	-	-	-	-	-	UPF0047
LZS3_k127_6386975_11	1244869.H261_09217	2.287e-92	313.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,2TRNC@28211|Alphaproteobacteria,2JVTD@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6386975_16	1379698.RBG1_1C00001G1318	4.409e-54	204.0	COG0392@1|root,COG0392@2|Bacteria,2NPGZ@2323|unclassified Bacteria	2|Bacteria	S	Lysylphosphatidylglycerol synthase TM region	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
LZS3_k127_6386975_17	1192034.CAP_0949	5.012e-53	191.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2Z10D@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
LZS3_k127_655064_0	443143.GM18_0801	3.691e-174	565.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
LZS3_k127_655064_10	1713.JOFV01000004_gene3455	1.315e-14	78.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4F2QP@85016|Cellulomonadaceae	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
LZS3_k127_655064_4	796942.HMPREF9623_00100	4.91e-47	178.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
LZS3_k127_655064_5	1050202.KB913024_gene2189	1.577e-41	155.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4094C@622450|Actinopolysporales	201174|Actinobacteria	J	Ribosomal protein L19	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
LZS3_k127_655064_3	1118054.CAGW01000028_gene561	6.975e-65	229.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,26RCU@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
LZS3_k127_655064_11	272134.KB731324_gene1179	2.57e-10	70.0	COG0806@1|root,COG0806@2|Bacteria,1G5WP@1117|Cyanobacteria,1HB1J@1150|Oscillatoriales	1117|Cyanobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
LZS3_k127_655064_9	555079.Toce_1067	1.001e-16	82.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,42H76@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
LZS3_k127_655064_6	1423758.BN55_03610	4.052e-27	115.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3F6VV@33958|Lactobacillaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
LZS3_k127_655064_1	867903.ThesuDRAFT_00298	1.642e-145	477.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3WCDI@538999|Clostridiales incertae sedis	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
LZS3_k127_655064_2	586413.CCDL010000002_gene2517	2.478e-65	233.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,23J53@182709|Oceanobacillus	91061|Bacilli	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
LZS3_k127_655064_8	643648.Slip_0866	3.418e-19	100.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42JMD@68298|Syntrophomonadaceae	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS3_k127_655064_7	1191523.MROS_0520	1.72e-24	111.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Porin_2
LZS3_k127_6636673_25	1121933.AUHH01000027_gene1282	5.386e-05	55.0	COG1403@1|root,COG1403@2|Bacteria,2GQ5J@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
LZS3_k127_6636673_0	1303518.CCALI_00532	4.405e-176	572.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
LZS3_k127_6636673_15	55207.KP22_14560	7.794e-35	146.0	COG1310@1|root,COG1310@2|Bacteria,1QRZQ@1224|Proteobacteria,1S558@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	JAB1/Mov34/MPN/PAD-1 ubiquitin protease	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
LZS3_k127_6636673_5	1303518.CCALI_00534	9.005e-118	392.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_6636673_20	644282.Deba_0361	1.983e-20	104.0	2CG1Y@1|root,32WID@2|Bacteria,1N01A@1224|Proteobacteria,42UK0@68525|delta/epsilon subdivisions,2WQED@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573,PapD-like
LZS3_k127_6636673_22	335543.Sfum_3060	3.096e-09	67.0	2CC24@1|root,32VJT@2|Bacteria,1N5Y6@1224|Proteobacteria,42UPP@68525|delta/epsilon subdivisions,2WQ6U@28221|Deltaproteobacteria,2MSB1@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
LZS3_k127_6636673_11	1403819.BATR01000117_gene4029	5.327e-47	182.0	COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
LZS3_k127_6636673_21	1380394.JADL01000007_gene4617	5.435e-19	102.0	COG0438@1|root,COG0438@2|Bacteria,1MWYH@1224|Proteobacteria,2UBKP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
LZS3_k127_6636673_9	1134413.ANNK01000144_gene3873	3.483e-62	241.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus	91061|Bacilli	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	3.7.1.5	ko:K16164	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
LZS3_k127_6636673_3	1047013.AQSP01000130_gene1847	2.874e-134	458.0	COG4232@1|root,COG4232@2|Bacteria,2NPKJ@2323|unclassified Bacteria	2|Bacteria	CO	Protein of unknown function, DUF255	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin,Thioredoxin_2,Thioredoxin_7
LZS3_k127_6636673_12	1124780.ANNU01000067_gene431	2.258e-42	175.0	COG1575@1|root,COG2249@1|root,COG1575@2|Bacteria,COG2249@2|Bacteria,4NM3V@976|Bacteroidetes,47PKG@768503|Cytophagia	976|Bacteroidetes	H	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2,UbiA
LZS3_k127_6636673_7	391625.PPSIR1_22976	1.785e-70	246.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,43BAG@68525|delta/epsilon subdivisions,2X6PP@28221|Deltaproteobacteria,2YUZG@29|Myxococcales	28221|Deltaproteobacteria	H	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
LZS3_k127_6636673_13	1121430.JMLG01000001_gene2090	1.984e-35	147.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia,261XP@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	pspA	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
LZS3_k127_6636673_14	395961.Cyan7425_3984	4.934e-35	142.0	COG3222@1|root,COG3222@2|Bacteria,1G536@1117|Cyanobacteria,3KHXX@43988|Cyanothece	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
LZS3_k127_6636673_16	316067.Geob_0462	1.504e-34	135.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42W9X@68525|delta/epsilon subdivisions,2WSEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA-1	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
LZS3_k127_6636673_8	1244531.CIG1485E_0172	1.139e-68	239.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2YMUT@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
LZS3_k127_6636673_17	653733.Selin_0889	2.11e-32	141.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	ndhJ	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0050136,GO:0055114,GO:0071944	1.6.5.3	ko:K00332,ko:K05581,ko:K13378	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iJN678.ndhJ	Complex1_30kDa,Complex1_49kDa
LZS3_k127_6636673_2	653733.Selin_0888	2.666e-145	472.0	COG0649@1|root,COG0649@2|Bacteria	2|Bacteria	C	NAD binding	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
LZS3_k127_6636673_10	1565314.OA34_02020	1.218e-48	179.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SRI@68525|delta/epsilon subdivisions,2YQ7X@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	NADH-quinone oxidoreductase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
LZS3_k127_6636673_1	118005.AWNK01000006_gene1204	7.595e-165	529.0	COG1894@1|root,COG1894@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
LZS3_k127_6636673_6	290397.Adeh_2566	7.724e-106	367.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WKMJ@28221|Deltaproteobacteria,2YU8F@29|Myxococcales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
LZS3_k127_6636673_4	1121403.AUCV01000026_gene2346	1.503e-122	410.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
LZS3_k127_6636673_18	1041826.FCOL_00125	6.745e-25	109.0	COG0839@1|root,COG0839@2|Bacteria,4NP2V@976|Bacteroidetes,1I32F@117743|Flavobacteriia,2NU90@237|Flavobacterium	976|Bacteroidetes	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
LZS3_k127_6636673_19	1504319.GM45_4170	2.203e-21	106.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,3UWX9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
LZS3_k127_6636673_24	1121921.KB898706_gene2782	1.467e-08	61.0	COG3637@1|root,COG3637@2|Bacteria,1RI4B@1224|Proteobacteria,1S8IK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
LZS3_k127_6645136_4	452662.SJA_C1-32250	3.375e-107	364.0	2DM50@1|root,31R6R@2|Bacteria,1N0T3@1224|Proteobacteria,2UD9J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6645136_5	1121920.AUAU01000012_gene2645	2.682e-101	339.0	COG0320@1|root,COG0320@2|Bacteria,3Y3D4@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
LZS3_k127_6645136_9	671143.DAMO_1594	1.437e-56	205.0	COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181,2.8.1.8	ko:K03644,ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07767,R07768,R07769	RC00039,RC00992,RC01978,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
LZS3_k127_6645136_2	1121920.AUAU01000004_gene789	9.744e-122	403.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
LZS3_k127_6645136_0	234267.Acid_0353	8.904e-146	481.0	COG0022@1|root,COG0022@2|Bacteria,3Y48G@57723|Acidobacteria	57723|Acidobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
LZS3_k127_6645136_3	234267.Acid_0352	1.305e-117	389.0	COG1071@1|root,COG1071@2|Bacteria,3Y4M3@57723|Acidobacteria	57723|Acidobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
LZS3_k127_6645136_6	861299.J421_3598	1.218e-87	302.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
LZS3_k127_6645136_1	743722.Sph21_3439	1.574e-133	440.0	COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,1IQG6@117747|Sphingobacteriia	976|Bacteroidetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
LZS3_k127_6645136_11	1123508.JH636442_gene3994	3.24e-28	122.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
LZS3_k127_6645136_12	1232410.KI421418_gene2352	2.71e-14	82.0	COG3584@1|root,COG3584@2|Bacteria,1NMA8@1224|Proteobacteria,42XYE@68525|delta/epsilon subdivisions,2WTAA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	3D domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6645136_10	1463903.JOIZ01000019_gene6602	3.959e-33	138.0	COG0726@1|root,COG0726@2|Bacteria,2H6C7@201174|Actinobacteria	201174|Actinobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS3_k127_6645136_8	1267534.KB906757_gene899	2.269e-79	278.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
LZS3_k127_6645136_7	1459636.NTE_00604	3.095e-82	283.0	COG0260@1|root,arCOG04322@2157|Archaea,41SYD@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
LZS3_k127_6652465_22	643867.Ftrac_1537	6.49e-11	67.0	COG0845@1|root,COG0845@2|Bacteria,4NT55@976|Bacteroidetes,47Q0W@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347
LZS3_k127_6652465_0	1125863.JAFN01000001_gene1438	0.0	1243.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
LZS3_k127_6652465_21	481448.Minf_0272	1.293e-11	71.0	2CK2Q@1|root,30XDX@2|Bacteria,46X4H@74201|Verrucomicrobia,37HA6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6652465_23	439235.Dalk_1475	1.057e-06	59.0	COG1470@1|root,COG4733@1|root,COG1470@2|Bacteria,COG4733@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2MN90@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_2,DUF4215
LZS3_k127_6652465_2	391625.PPSIR1_40929	4.726e-119	402.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,4360M@68525|delta/epsilon subdivisions,2X2HZ@28221|Deltaproteobacteria,2Z0WC@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
LZS3_k127_6652465_11	1396418.BATQ01000019_gene4981	1.743e-19	98.0	COG0457@1|root,COG0457@2|Bacteria,46VTD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6652465_15	1001530.BACE01000028_gene3919	7.311e-14	80.0	2ATWF@1|root,31JFP@2|Bacteria,1RK55@1224|Proteobacteria,1SIQT@1236|Gammaproteobacteria,1XVPA@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6652465_14	1379698.RBG1_1C00001G1428	3.739e-15	90.0	COG2911@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NS5I@2323|unclassified Bacteria	2|Bacteria	U	FlgD Ig-like domain	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,FlgD_ig,PKD,SLH
LZS3_k127_6652465_4	1254432.SCE1572_50715	8.699e-63	242.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_6652465_13	1191523.MROS_2324	2.52e-18	95.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,PSII_BNR
LZS3_k127_6652465_19	459349.CLOAM0061	1.922e-12	81.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	wprA	-	3.1.3.6,3.1.4.16,3.2.1.99	ko:K01119,ko:K06113,ko:K12685,ko:K20276	ko00230,ko00240,ko02024,map00230,map00240,map02024	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3	GH43	-	Mucin_bdg,Peptidase_M60,Peptidase_S8,SLH
LZS3_k127_6652465_3	1192034.CAP_2122	3.894e-85	312.0	COG1520@1|root,COG2863@1|root,COG1520@2|Bacteria,COG2863@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_6652465_12	344747.PM8797T_13912	8.848e-19	101.0	COG3063@1|root,COG3063@2|Bacteria,2J0A8@203682|Planctomycetes	203682|Planctomycetes	NU	O-linked GlcNAc transferase-putative TPR-containing transmembrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_6652465_17	880073.Calab_2081	2.032e-13	84.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_6652465_16	754436.JCM19237_6396	9.228e-14	78.0	2BN55@1|root,32GS7@2|Bacteria,1R7WY@1224|Proteobacteria,1RQ71@1236|Gammaproteobacteria,1XU9A@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6652465_18	1089550.ATTH01000001_gene2205	5.026e-13	83.0	COG4775@1|root,COG4775@2|Bacteria,4P624@976|Bacteroidetes,1FIN0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
LZS3_k127_6652465_20	1469607.KK073769_gene5501	1.235e-11	79.0	COG0457@1|root,COG0457@2|Bacteria,1G20P@1117|Cyanobacteria,1HIQE@1161|Nostocales	1117|Cyanobacteria	K	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
LZS3_k127_6652465_9	861299.J421_1461	1.676e-33	151.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
LZS3_k127_6652465_7	886293.Sinac_6279	1.512e-40	153.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
LZS3_k127_6652465_8	1454007.JAUG01000052_gene2595	2.55e-35	151.0	COG4249@1|root,COG4249@2|Bacteria,4NKV1@976|Bacteroidetes,1IXN5@117747|Sphingobacteriia	976|Bacteroidetes	V	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
LZS3_k127_6652465_1	671143.DAMO_1249	4.391e-242	777.0	COG1615@1|root,COG1615@2|Bacteria,2NQSF@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0182)	-	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
LZS3_k127_6652465_6	313612.L8106_27254	1.867e-44	187.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H8D7@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
LZS3_k127_6652465_10	1380347.JNII01000006_gene1446	1.482e-21	110.0	COG1749@1|root,COG2372@1|root,COG5184@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG5184@2|Bacteria,2I2X3@201174|Actinobacteria,4EUDH@85013|Frankiales	201174|Actinobacteria	N	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,Mo-co_dimer,fn3
LZS3_k127_6679943_24	478749.BRYFOR_05712	9.89e-07	55.0	2ADFQ@1|root,3135S@2|Bacteria,1VQ83@1239|Firmicutes,24WNI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6679943_18	596152.DesU5LDRAFT_2985	2.5e-35	136.0	COG1343@1|root,COG1343@2|Bacteria,1MZ9Q@1224|Proteobacteria,42UMG@68525|delta/epsilon subdivisions,2WQ4N@28221|Deltaproteobacteria,2MCEY@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
LZS3_k127_6679943_8	56780.SYN_02473	1.505e-131	427.0	COG1518@1|root,COG1518@2|Bacteria,1MUKK@1224|Proteobacteria,42NHJ@68525|delta/epsilon subdivisions,2WJ13@28221|Deltaproteobacteria,2MRDX@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
LZS3_k127_6679943_15	706587.Desti_0798	4.46e-61	220.0	COG1468@1|root,COG1468@2|Bacteria,1MX2S@1224|Proteobacteria,42R51@68525|delta/epsilon subdivisions,2WMQZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	TIGRFAM CRISPR-associated protein Cas4	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
LZS3_k127_6679943_11	264732.Moth_0495	7.198e-86	293.0	COG3649@1|root,COG3649@2|Bacteria,1TQZ8@1239|Firmicutes,248MT@186801|Clostridia,42EP6@68295|Thermoanaerobacterales	186801|Clostridia	L	CRISPR-associated protein, Csh2 family	csh2	-	-	ko:K19115,ko:K19118	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
LZS3_k127_6679943_12	1192034.CAP_3264	8.588e-73	270.0	28HN3@1|root,2Z7WH@2|Bacteria,1MWH8@1224|Proteobacteria,42NC5@68525|delta/epsilon subdivisions,2WJPW@28221|Deltaproteobacteria,2YW8V@29|Myxococcales	28221|Deltaproteobacteria	S	CRISPR-associated protein (Cas_Csd1)	csd1	-	-	ko:K19117	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csd1
LZS3_k127_6679943_14	243365.CV_1225	3.853e-66	232.0	2DBAF@1|root,2Z82V@2|Bacteria,1MWRM@1224|Proteobacteria,2VM7J@28216|Betaproteobacteria,2KQ6P@206351|Neisseriales	206351|Neisseriales	S	CRISPR-associated protein Cas5, Dvulg subtype	cas5d	-	-	ko:K19119	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
LZS3_k127_6679943_5	1192034.CAP_3266	4.189e-153	511.0	COG1203@1|root,COG1203@2|Bacteria,1MX7A@1224|Proteobacteria,42Q2Q@68525|delta/epsilon subdivisions,2WJEP@28221|Deltaproteobacteria,2YYWX@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD-like helicases superfamily	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
LZS3_k127_6679943_9	478741.JAFS01000001_gene1316	1.205e-110	371.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78
LZS3_k127_6679943_20	478741.JAFS01000001_gene1317	1.05e-28	121.0	COG2405@1|root,COG2405@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	-
LZS3_k127_6679943_13	1068980.ARVW01000001_gene6991	1.182e-72	256.0	COG3191@1|root,COG3191@2|Bacteria,2GJKQ@201174|Actinobacteria	201174|Actinobacteria	EQ	peptidase S58, DmpA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
LZS3_k127_6679943_1	1124780.ANNU01000008_gene2769	1.307e-266	833.0	COG1164@1|root,COG1164@2|Bacteria,4NJFW@976|Bacteroidetes,47TFT@768503|Cytophagia	976|Bacteroidetes	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
LZS3_k127_6679943_17	1089544.KB912942_gene7836	2.297e-51	201.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4E85D@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K16029	ko01051,ko01052,map01051,map01052	-	-	-	ko00000,ko00001	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH
LZS3_k127_6679943_21	1449976.KALB_5687	4.62e-21	106.0	COG3153@1|root,COG3153@2|Bacteria,2H2RA@201174|Actinobacteria	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
LZS3_k127_6679943_16	75379.Tint_3118	2.855e-54	207.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,2VQZE@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS3_k127_6679943_2	929556.Solca_3240	4.748e-199	642.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,1IQQY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase S9, prolyl oligopeptidase, catalytic domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS3_k127_6679943_6	1128421.JAGA01000003_gene2811	3.354e-142	463.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_6679943_0	497964.CfE428DRAFT_1447	0.0	1085.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
LZS3_k127_6679943_10	1519464.HY22_10905	6.409e-106	352.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
LZS3_k127_6679943_26	1379698.RBG1_1C00001G1194	9.482e-06	57.0	COG2911@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,2NNYR@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	3.2.1.91	ko:K14194,ko:K19668	ko00500,ko01100,ko02020,ko05150,map00500,map01100,map02020,map05150	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CHU_C,DUF11,FlgD_ig,PKD,SdrD_B
LZS3_k127_6679943_4	977880.RALTA_B0323	6.49e-167	538.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VZWJ@28216|Betaproteobacteria,1KH73@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3,SLT
LZS3_k127_6679943_22	880073.Calab_3451	1.392e-16	94.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_5,Cadherin_3,Cleaved_Adhesin,FlgD_ig,HemolysinCabind,Kelch_1,Kelch_4,OmpA_membrane
LZS3_k127_6679943_23	56110.Oscil6304_2815	5.258e-11	76.0	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
LZS3_k127_6679943_27	1047013.AQSP01000142_gene167	6.618e-05	55.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	ywhL	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
LZS3_k127_6679943_3	743722.Sph21_1459	1.004e-174	559.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
LZS3_k127_6679943_7	234267.Acid_5749	4.035e-135	456.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
LZS3_k127_6721365_3	562970.Btus_1419	4.153e-10	63.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,277Z1@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
LZS3_k127_6721365_2	880073.Calab_0007	2.139e-65	231.0	COG1573@1|root,COG1573@2|Bacteria,2NP99@2323|unclassified Bacteria	2|Bacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
LZS3_k127_6721365_0	177437.HRM2_38570	1.389e-96	336.0	COG0674@1|root,COG0674@2|Bacteria,1R4K0@1224|Proteobacteria,42NQJ@68525|delta/epsilon subdivisions,2WJ0K@28221|Deltaproteobacteria,2MIND@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
LZS3_k127_6721365_1	1121405.dsmv_2999	2.769e-80	286.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,1R7US@1224|Proteobacteria,42PFT@68525|delta/epsilon subdivisions,2WMBJ@28221|Deltaproteobacteria,2MJ1Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,TPP_enzyme_C
LZS3_k127_6810017_4	1408473.JHXO01000001_gene1949	1.974e-62	231.0	COG3104@1|root,COG3104@2|Bacteria,4NIIT@976|Bacteroidetes,2FR16@200643|Bacteroidia	976|Bacteroidetes	E	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
LZS3_k127_6810017_0	388413.ALPR1_16858	4.922e-90	304.0	COG0500@1|root,COG2226@2|Bacteria,4NIN6@976|Bacteroidetes,47JAJ@768503|Cytophagia	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
LZS3_k127_6810017_6	452637.Oter_1508	4.324e-15	80.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_C
LZS3_k127_6810017_2	1158318.ATXC01000001_gene377	4.045e-68	245.0	COG0177@1|root,COG0177@2|Bacteria,2G3TX@200783|Aquificae	200783|Aquificae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
LZS3_k127_6810017_7	1297742.A176_03811	9.244e-05	50.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
LZS3_k127_6810017_5	1125863.JAFN01000001_gene1525	5.291e-43	175.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
LZS3_k127_6810017_3	1343739.PAP_09585	2.307e-66	234.0	COG0327@1|root,arCOG04454@2157|Archaea,2XT5G@28890|Euryarchaeota,242U7@183968|Thermococci	183968|Thermococci	S	metal ion binding	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
LZS3_k127_6810017_1	429009.Adeg_0532	1.331e-77	278.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_6827508_13	555779.Dthio_PD2029	5.308e-24	105.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria,2MARP@213115|Desulfovibrionales	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
LZS3_k127_6827508_15	204669.Acid345_3322	5.075e-15	90.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria,2JIG4@204432|Acidobacteriia	204432|Acidobacteriia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6827508_6	880073.Calab_2504	5.794e-62	229.0	COG0795@1|root,COG0795@2|Bacteria,2NPHN@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
LZS3_k127_6827508_4	1379698.RBG1_1C00001G1858	5.636e-80	290.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
LZS3_k127_6827508_2	1379698.RBG1_1C00001G0435	3.18e-153	546.0	COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N,SprA_N
LZS3_k127_6827508_7	880074.BARVI_06355	1.003e-53	202.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,2FN1C@200643|Bacteroidia,22X6Y@171551|Porphyromonadaceae	976|Bacteroidetes	S	Glutamine cyclotransferase	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
LZS3_k127_6827508_11	502558.EGYY_12650	3.815e-28	130.0	COG0779@1|root,COG0779@2|Bacteria,2HUVT@201174|Actinobacteria,4CVTM@84998|Coriobacteriia	84998|Coriobacteriia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
LZS3_k127_6827508_3	1379698.RBG1_1C00001G1152	5.797e-120	403.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
LZS3_k127_6827508_1	1121428.DESHY_80091___1	1.462e-186	611.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
LZS3_k127_6827508_14	880073.Calab_3553	4.56e-20	93.0	COG1550@1|root,COG1550@2|Bacteria,2NPYX@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF503)	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
LZS3_k127_6827508_12	349161.Dred_1956	7.282e-25	109.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,262H0@186807|Peptococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
LZS3_k127_6827508_8	357808.RoseRS_3755	8.496e-50	194.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi,375GZ@32061|Chloroflexia	32061|Chloroflexia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
LZS3_k127_6827508_5	153721.MYP_2312	9.441e-66	235.0	COG0196@1|root,COG0196@2|Bacteria,4NEI9@976|Bacteroidetes,47JNP@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
LZS3_k127_6827508_10	56780.SYN_01782	1.919e-29	121.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
LZS3_k127_6827508_0	945713.IALB_0644	2.228e-231	737.0	COG1185@1|root,COG1185@2|Bacteria	2|Bacteria	J	polyribonucleotide nucleotidyltransferase activity	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
LZS3_k127_6827508_9	477974.Daud_0936	3.004e-38	148.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,260B8@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_6855244_14	502025.Hoch_5635	4.26e-55	196.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42NU9@68525|delta/epsilon subdivisions,2WKXG@28221|Deltaproteobacteria,2YU6A@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
LZS3_k127_6855244_12	945713.IALB_0987	2.504e-59	212.0	COG3040@1|root,COG3040@2|Bacteria	2|Bacteria	M	lipid binding	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
LZS3_k127_6855244_15	1121405.dsmv_3198	1.134e-54	194.0	COG3189@1|root,COG3189@2|Bacteria,1RHYB@1224|Proteobacteria,42SR4@68525|delta/epsilon subdivisions,2WPV2@28221|Deltaproteobacteria,2MNNT@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
LZS3_k127_6855244_13	945713.IALB_0041	1.43e-57	209.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	mhpC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
LZS3_k127_6855244_34	1110502.TMO_0439	3.067e-12	74.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria,2JZRZ@204441|Rhodospirillales	204441|Rhodospirillales	M	OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
LZS3_k127_6855244_21	1121875.KB907549_gene1917	8.114e-40	156.0	COG2928@1|root,COG2928@2|Bacteria,4NT13@976|Bacteroidetes,1I204@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
LZS3_k127_6855244_5	1045009.AFXQ01000036_gene1123	1.288e-81	283.0	COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,1WC1D@1268|Micrococcaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
LZS3_k127_6855244_17	485913.Krac_2610	1.118e-53	199.0	COG2513@1|root,COG2513@2|Bacteria	2|Bacteria	G	methylisocitrate lyase activity	MA20_35565	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
LZS3_k127_6855244_2	313590.MED134_07491	5e-139	478.0	COG1305@1|root,COG1305@2|Bacteria,4NF37@976|Bacteroidetes,1IIST@117743|Flavobacteriia	976|Bacteroidetes	E	Protein of unknown function (DUF2569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2569,DUF3857,Transglut_core
LZS3_k127_6855244_9	1163409.UUA_17210	3.488e-65	230.0	arCOG07533@1|root,2ZF5I@2|Bacteria,1RB8D@1224|Proteobacteria,1SBRH@1236|Gammaproteobacteria,1X79G@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
LZS3_k127_6855244_32	502025.Hoch_3323	9.17e-21	106.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,42YBA@68525|delta/epsilon subdivisions,2WUP5@28221|Deltaproteobacteria,2YX31@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
LZS3_k127_6855244_19	550540.Fbal_1923	9.327e-47	172.0	2C7KN@1|root,30RKS@2|Bacteria,1N486@1224|Proteobacteria,1T684@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6855244_7	1123257.AUFV01000012_gene2983	2.04e-71	245.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,1S4M7@1236|Gammaproteobacteria,1X6D4@135614|Xanthomonadales	135614|Xanthomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
LZS3_k127_6855244_0	706587.Desti_2502	0.0	1349.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,42PRE@68525|delta/epsilon subdivisions,2WJRD@28221|Deltaproteobacteria,2MRGT@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
LZS3_k127_6855244_25	1197906.CAJQ02000053_gene4311	1.381e-31	132.0	2DX6K@1|root,343MI@2|Bacteria,1NNUG@1224|Proteobacteria,2UJFB@28211|Alphaproteobacteria,3K5PG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6855244_28	880073.Calab_3503	4.819e-26	115.0	COG2929@1|root,COG2929@2|Bacteria,2NRJV@2323|unclassified Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
LZS3_k127_6855244_24	671143.DAMO_0643	2.902e-32	127.0	COG5304@1|root,COG5304@2|Bacteria,2NRFS@2323|unclassified Bacteria	2|Bacteria	S	CopG antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	CopG_antitoxin
LZS3_k127_6855244_22	1123248.KB893314_gene3458	2.461e-39	152.0	COG2318@1|root,COG2318@2|Bacteria,4NNRD@976|Bacteroidetes,1ITIY@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
LZS3_k127_6855244_3	330214.NIDE0014	1.803e-134	439.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
LZS3_k127_6855244_29	1265503.KB905195_gene2358	7.083e-23	101.0	2EG8Z@1|root,33A0S@2|Bacteria,1NKBI@1224|Proteobacteria,1SRMF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6855244_31	653045.Strvi_0656	1.685e-21	98.0	COG0724@1|root,COG0724@2|Bacteria,2H1J0@201174|Actinobacteria	201174|Actinobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_6855244_26	1267534.KB906760_gene1554	1.668e-28	119.0	2DD3Z@1|root,2ZGDH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6855244_4	1267535.KB906767_gene2749	2.63e-112	368.0	COG3620@1|root,COG3620@2|Bacteria,3Y6X6@57723|Acidobacteria	57723|Acidobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
LZS3_k127_6855244_23	323261.Noc_1455	4.026e-39	160.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,1RMX9@1236|Gammaproteobacteria,1WZ9C@135613|Chromatiales	135613|Chromatiales	I	PFAM Diacylglycerol kinase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
LZS3_k127_6855244_33	1121374.KB891575_gene1597	5.347e-14	77.0	COG3324@1|root,COG3324@2|Bacteria,1N7Q5@1224|Proteobacteria,1SB3Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
LZS3_k127_6855244_6	1517681.HW45_06100	4.606e-81	284.0	COG4775@1|root,COG4775@2|Bacteria,1QVN6@1224|Proteobacteria,1T2FG@1236|Gammaproteobacteria,1Y3BX@135623|Vibrionales	135623|Vibrionales	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
LZS3_k127_6855244_8	595460.RRSWK_05929	2.838e-70	255.0	COG3527@1|root,COG3527@2|Bacteria,2J4RG@203682|Planctomycetes	203682|Planctomycetes	Q	Alpha-acetolactate decarboxylase	-	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	-
LZS3_k127_6855244_11	338963.Pcar_2867	1.881e-64	224.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WQMW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
LZS3_k127_6855244_1	338963.Pcar_2866	2.617e-243	761.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,43UNQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
LZS3_k127_6855244_27	330214.NIDE2626	1.984e-26	111.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
LZS3_k127_6855244_18	330214.NIDE2627	3.903e-47	171.0	COG4679@1|root,COG4679@2|Bacteria	2|Bacteria	K	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
LZS3_k127_6855244_10	1499967.BAYZ01000156_gene556	7.273e-65	229.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K20444	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
LZS3_k127_6855244_20	1121015.N789_10825	2.113e-43	165.0	2CN2H@1|root,32SG5@2|Bacteria,1N4PY@1224|Proteobacteria,1SESE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6855244_16	1286106.MPL1_02313	5.184e-54	198.0	2B14M@1|root,31TIF@2|Bacteria,1RH0J@1224|Proteobacteria,1S6U0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2938
LZS3_k127_6855244_30	1232437.KL661961_gene2948	8.886e-22	102.0	2EG6A@1|root,339Y4@2|Bacteria,1NIH0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
LZS3_k127_6894901_45	1410634.JHVD01000006_gene1326	3.789e-18	98.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2GJD0@201174|Actinobacteria,4DPY8@85009|Propionibacteriales	201174|Actinobacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
LZS3_k127_6894901_5	671143.DAMO_2552	5.079e-150	487.0	COG2256@1|root,COG2256@2|Bacteria,2NNTG@2323|unclassified Bacteria	2|Bacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
LZS3_k127_6894901_21	404589.Anae109_2171	1.443e-82	291.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2WKJ6@28221|Deltaproteobacteria,2YX5K@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
LZS3_k127_6894901_48	518766.Rmar_0157	7.58e-14	84.0	COG0457@1|root,COG4235@1|root,COG0457@2|Bacteria,COG4235@2|Bacteria,4NG1I@976|Bacteroidetes,1FJ3E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
LZS3_k127_6894901_49	243231.GSU1057	3.598e-12	76.0	COG0457@1|root,COG0457@2|Bacteria,1P22J@1224|Proteobacteria,4310H@68525|delta/epsilon subdivisions,2WWBW@28221|Deltaproteobacteria,43VHQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6894901_28	460265.Mnod_1497	8.221e-57	212.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,2TTFW@28211|Alphaproteobacteria,1JQV8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBS,Peptidase_M50
LZS3_k127_6894901_44	869210.Marky_0902	3.306e-22	113.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N
LZS3_k127_6894901_53	1396141.BATP01000004_gene5900	0.0005577	53.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	sacC	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Big_2,CW_binding_1,Cadherin-like,DUF1080,DUF4980,G5,Glyco_hydro_32C,Glyco_hydro_32N,Gram_pos_anchor
LZS3_k127_6894901_46	880073.Calab_2081	4.813e-17	96.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_6894901_31	243090.RB13330	2.213e-52	209.0	COG0457@1|root,COG5305@1|root,COG0457@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_6894901_34	756272.Plabr_4381	3.981e-46	174.0	COG0461@1|root,COG0461@2|Bacteria,2IZA7@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
LZS3_k127_6894901_19	926562.Oweho_1655	3.517e-87	316.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1HWQI@117743|Flavobacteriia,2PA72@246874|Cryomorphaceae	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_6894901_18	1124780.ANNU01000072_gene1056	9.718e-92	338.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,47M1B@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
LZS3_k127_6894901_2	867903.ThesuDRAFT_00352	2.683e-181	597.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
LZS3_k127_6894901_33	1142394.PSMK_05040	4.492e-49	183.0	COG0388@1|root,COG0388@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_6894901_13	1142394.PSMK_05030	1.084e-108	359.0	COG0388@1|root,COG0388@2|Bacteria,2IXDC@203682|Planctomycetes	203682|Planctomycetes	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
LZS3_k127_6894901_42	688269.Theth_0209	1.376e-28	120.0	COG0394@1|root,COG0394@2|Bacteria,2GDH0@200918|Thermotogae	200918|Thermotogae	T	PFAM low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
LZS3_k127_6894901_35	1501391.LG35_00500	3.941e-45	186.0	COG0500@1|root,COG2226@2|Bacteria,4NEDR@976|Bacteroidetes,2FMI3@200643|Bacteroidia,22UXJ@171550|Rikenellaceae	976|Bacteroidetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
LZS3_k127_6894901_12	1121904.ARBP01000010_gene2290	6.289e-112	378.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,47K2Q@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
LZS3_k127_6894901_17	388413.ALPR1_14479	1.43e-94	326.0	COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,47K2Q@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
LZS3_k127_6894901_15	945713.IALB_1280	1.111e-99	346.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH,SGL
LZS3_k127_6894901_24	105559.Nwat_0851	5.301e-64	227.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,1RXUZ@1236|Gammaproteobacteria,1WY3R@135613|Chromatiales	135613|Chromatiales	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
LZS3_k127_6894901_26	195250.CM001776_gene862	1.001e-59	224.0	COG0398@1|root,COG0398@2|Bacteria,1G3R9@1117|Cyanobacteria,1H2WN@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
LZS3_k127_6894901_23	1356852.N008_19465	1.622e-68	242.0	COG0463@1|root,COG0463@2|Bacteria,4PKIQ@976|Bacteroidetes,47YFC@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
LZS3_k127_6894901_29	237368.SCABRO_01833	1.16e-55	215.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.7.8.20	ko:K01002,ko:K20534	ko01100,map01100	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	GT87,Glycos_transf_2
LZS3_k127_6894901_8	378806.STAUR_6405	3.827e-141	463.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
LZS3_k127_6894901_0	485913.Krac_9382	5.219e-268	848.0	COG1505@1|root,COG1505@2|Bacteria,2GBNH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
LZS3_k127_6894901_14	518766.Rmar_2099	8.898e-104	349.0	COG0665@1|root,COG0665@2|Bacteria,4PEB4@976|Bacteroidetes,1FIQR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
LZS3_k127_6894901_51	1214242.B446_11070	1.149e-09	68.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
LZS3_k127_6894901_10	517418.Ctha_2046	1.25e-120	393.0	COG2022@1|root,COG2022@2|Bacteria,1FEZV@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
LZS3_k127_6894901_40	1232410.KI421428_gene1185	7.682e-33	143.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,43UPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
LZS3_k127_6894901_30	517418.Ctha_2042	4.847e-54	201.0	COG0352@1|root,COG0352@2|Bacteria,1FDY5@1090|Chlorobi	1090|Chlorobi	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
LZS3_k127_6894901_50	554065.XP_005850298.1	1.67e-10	74.0	2CYB0@1|root,2S3AJ@2759|Eukaryota,37VHI@33090|Viridiplantae,34I74@3041|Chlorophyta	3041|Chlorophyta	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
LZS3_k127_6894901_39	485918.Cpin_7086	7.095e-33	132.0	COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,1IYT5@117747|Sphingobacteriia	976|Bacteroidetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
LZS3_k127_6894901_43	743721.Psesu_2295	1.111e-26	122.0	COG0662@1|root,COG0662@2|Bacteria,1QUHG@1224|Proteobacteria,1T1Z6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
LZS3_k127_6894901_32	886293.Sinac_6834	3.319e-49	179.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	ymaD	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
LZS3_k127_6894901_9	671143.DAMO_0966	2.284e-128	420.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	spoIVFB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
LZS3_k127_6894901_22	518766.Rmar_2095	3.131e-78	272.0	COG0351@1|root,COG0351@2|Bacteria,4NE0F@976|Bacteroidetes,1FIQS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
LZS3_k127_6894901_20	521045.Kole_0509	3.035e-84	286.0	COG1794@1|root,COG1794@2|Bacteria	2|Bacteria	M	racemase activity, acting on amino acids and derivatives	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS14520	Asp_Glu_race
LZS3_k127_6894901_4	1379270.AUXF01000004_gene3094	4.431e-159	523.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
LZS3_k127_6894901_47	313603.FB2170_14823	6.064e-17	94.0	2919D@1|root,2ZNWG@2|Bacteria,4NMU5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6894901_3	204669.Acid345_0471	2.646e-164	535.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6894901_11	880073.Calab_3334	8.71e-119	403.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
LZS3_k127_6894901_16	880073.Calab_3330	3.644e-99	340.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,2NS2I@2323|unclassified Bacteria	2|Bacteria	O	Pyridine nucleotide-disulphide oxidoreductase	trxB_2	-	1.18.1.2,1.19.1.1,1.8.1.9	ko:K00384,ko:K21567	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,Pyr_redox_3
LZS3_k127_6894901_41	1408473.JHXO01000005_gene1870	1.589e-30	133.0	COG0492@1|root,COG0492@2|Bacteria,4NNAA@976|Bacteroidetes,2FXF6@200643|Bacteroidia	976|Bacteroidetes	O	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6894901_1	693661.Arcve_0993	1.103e-207	675.0	COG0383@1|root,arCOG03661@2157|Archaea,2XVNX@28890|Euryarchaeota	28890|Euryarchaeota	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
LZS3_k127_6894901_36	1123368.AUIS01000030_gene1245	5.372e-45	169.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
LZS3_k127_6894901_6	693661.Arcve_1325	1.364e-147	488.0	COG0367@1|root,COG0449@1|root,arCOG00057@2157|Archaea,arCOG00071@2157|Archaea,2XSYP@28890|Euryarchaeota	28890|Euryarchaeota	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_6,GATase_7
LZS3_k127_6894901_7	518766.Rmar_0502	9.923e-145	469.0	COG1215@1|root,COG1215@2|Bacteria,4P244@976|Bacteroidetes	976|Bacteroidetes	M	Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth)	-	-	2.4.1.217	ko:K05947	ko00051,map00051	-	R05768	RC00005,RC00397,RC02748	ko00000,ko00001,ko01000,ko01003	-	-	-	Osmo_MPGsynth
LZS3_k127_6894901_25	869210.Marky_0081	5.613e-64	233.0	COG3769@1|root,COG3769@2|Bacteria,1WMJU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
LZS3_k127_6894901_38	1121920.AUAU01000004_gene618	2.244e-38	151.0	COG2318@1|root,COG2318@2|Bacteria,3Y53M@57723|Acidobacteria	57723|Acidobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS3_k127_6894901_27	748449.Halha_2397	5.206e-59	218.0	COG0438@1|root,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,25EAY@186801|Clostridia,3WBCZ@53433|Halanaerobiales	186801|Clostridia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_6894901_37	298386.PBPRA1243	9.132e-39	154.0	COG3187@1|root,COG3895@1|root,COG4461@1|root,COG3187@2|Bacteria,COG3895@2|Bacteria,COG4461@2|Bacteria,1PF0Q@1224|Proteobacteria,1TBDV@1236|Gammaproteobacteria,1XWBZ@135623|Vibrionales	135623|Vibrionales	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
LZS3_k127_691989_0	1121405.dsmv_0170	1.191e-203	650.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2MHT0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
LZS3_k127_691989_15	82996.sch_06015	1.937e-14	87.0	COG5305@1|root,COG5305@2|Bacteria,1R9UF@1224|Proteobacteria,1S0JK@1236|Gammaproteobacteria,401GG@613|Serratia	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_691989_14	273526.SMDB11_0418	4.828e-19	101.0	COG5305@1|root,COG5305@2|Bacteria,1R9UF@1224|Proteobacteria,1S0JK@1236|Gammaproteobacteria,401GG@613|Serratia	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
LZS3_k127_691989_6	1120973.AQXL01000107_gene1971	1.087e-72	256.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,4HA3H@91061|Bacilli	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
LZS3_k127_691989_2	1047013.AQSP01000089_gene1175	3.944e-165	527.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metC	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
LZS3_k127_691989_7	1118235.CAJH01000044_gene2815	1.569e-69	259.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RZA4@1236|Gammaproteobacteria,1X7KS@135614|Xanthomonadales	135614|Xanthomonadales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
LZS3_k127_691989_16	653045.Strvi_6395	1.791e-10	74.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
LZS3_k127_691989_4	945713.IALB_2990	1.916e-82	282.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4397
LZS3_k127_691989_19	391625.PPSIR1_16080	0.0006664	49.0	2EIJE@1|root,33CAQ@2|Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_691989_13	1125863.JAFN01000001_gene1366	5.174e-26	115.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42URE@68525|delta/epsilon subdivisions,2WR5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_691989_18	1197706.AKKK01000009_gene630	0.0004406	49.0	COG1595@1|root,COG1595@2|Bacteria,2GJFK@201174|Actinobacteria,1W9QB@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
LZS3_k127_691989_5	28072.Nos7524_2690	2.298e-79	270.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1HK26@1161|Nostocales	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
LZS3_k127_691989_8	351607.Acel_1993	8.645e-65	230.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4ERX8@85013|Frankiales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
LZS3_k127_691989_1	403833.Pmob_0486	8.516e-188	603.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GE9T@200918|Thermotogae	200918|Thermotogae	L	DNA polymerase alpha chain like domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	PHP
LZS3_k127_691989_11	272844.PAB1737	4.229e-36	148.0	COG0543@1|root,arCOG02199@2157|Archaea,2XTVJ@28890|Euryarchaeota,243NE@183968|Thermococci	183968|Thermococci	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	1.8.1.19	ko:K20203	-	-	-	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind
LZS3_k127_691989_3	880073.Calab_1897	2.369e-127	416.0	COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
LZS3_k127_691989_10	313628.LNTAR_14402	3.336e-40	163.0	COG0564@1|root,COG0564@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,Rhodanese
LZS3_k127_691989_9	522306.CAP2UW1_2595	2.337e-49	185.0	COG3015@1|root,COG3126@1|root,COG3187@1|root,COG3015@2|Bacteria,COG3126@2|Bacteria,COG3187@2|Bacteria,1N8AF@1224|Proteobacteria,2VXB0@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Type III secretion system lipoprotein chaperone (YscW)	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	MliC,YscW
LZS3_k127_691989_12	1278307.KB906976_gene1599	1.433e-27	124.0	COG3126@1|root,COG3187@1|root,COG3126@2|Bacteria,COG3187@2|Bacteria,1N9XV@1224|Proteobacteria,1S4T0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	protein conserved in bacteria	-	-	-	ko:K09914	-	-	-	-	ko00000	-	-	-	META,NlpE,NlpE_C,YscW
LZS3_k127_6946465_17	1123279.ATUS01000005_gene3151	7.183e-34	149.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,1T462@1236|Gammaproteobacteria,1JAZP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
LZS3_k127_6946465_22	575540.Isop_2854	2.43e-13	78.0	COG1595@1|root,COG1595@2|Bacteria,2J08Y@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_6946465_23	469596.HMPREF9488_00839	7.76e-12	74.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,3VTEP@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
LZS3_k127_6946465_5	237368.SCABRO_01193	6.275e-148	487.0	COG0674@1|root,COG0674@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
LZS3_k127_6946465_6	1521187.JPIM01000004_gene3035	2.161e-92	312.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia	32061|Chloroflexia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
LZS3_k127_6946465_24	398580.Dshi_1334	2.729e-08	66.0	COG0457@1|root,COG0457@2|Bacteria	398580.Dshi_1334|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6946465_13	1382306.JNIM01000001_gene1504	1.149e-48	188.0	COG5653@1|root,COG5653@2|Bacteria,2G8SZ@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
LZS3_k127_6946465_1	204669.Acid345_2392	1.189e-209	659.0	COG1260@1|root,COG1260@2|Bacteria,3Y325@57723|Acidobacteria,2JIPN@204432|Acidobacteriia	204432|Acidobacteriia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
LZS3_k127_6946465_15	1125863.JAFN01000001_gene1349	1.048e-46	179.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42U74@68525|delta/epsilon subdivisions,2WQ6J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS3_k127_6946465_9	1046714.AMRX01000007_gene1911	9.382e-66	240.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,464K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	suhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2538,iPC815.YPO2899	Inositol_P
LZS3_k127_6946465_12	1379698.RBG1_1C00001G1816	1.4e-56	224.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NR9R@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2,TPR_8
LZS3_k127_6946465_7	517418.Ctha_1804	2.823e-86	291.0	COG2859@1|root,COG2859@2|Bacteria,1FEXS@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
LZS3_k127_6946465_21	1223410.KN050846_gene441	1.605e-13	83.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia	976|Bacteroidetes	M	Opacity protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
LZS3_k127_6946465_16	983545.Glaag_2326	3.133e-42	171.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,465RR@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
LZS3_k127_6946465_0	1442599.JAAN01000020_gene2554	3.248e-254	818.0	COG0841@1|root,COG0845@1|root,COG0841@2|Bacteria,COG0845@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3PQ@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_6946465_2	1121930.AQXG01000001_gene1202	2.823e-190	638.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_6946465_3	84531.JMTZ01000070_gene1797	1.083e-180	576.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,1RNQ7@1236|Gammaproteobacteria,1XCI2@135614|Xanthomonadales	135614|Xanthomonadales	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
LZS3_k127_6946465_8	580332.Slit_1984	1.262e-85	289.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
LZS3_k127_6946465_20	1254432.SCE1572_06780	4.384e-23	115.0	COG0457@1|root,COG0457@2|Bacteria,1R157@1224|Proteobacteria,43D6R@68525|delta/epsilon subdivisions,2X8DJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6946465_14	237368.SCABRO_01812	1.769e-48	184.0	COG1262@1|root,COG1262@2|Bacteria,2J0WC@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
LZS3_k127_6946465_18	1182590.BN5_00346	3.282e-32	137.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,1RPT8@1236|Gammaproteobacteria,1YHBU@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
LZS3_k127_6946465_19	1047013.AQSP01000032_gene1975	2.212e-30	133.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,TolB_like
LZS3_k127_6946465_25	1122989.KB898602_gene84	6.094e-08	62.0	COG1372@1|root,COG3209@1|root,COG1372@2|Bacteria,COG3209@2|Bacteria,4NXRQ@976|Bacteroidetes	976|Bacteroidetes	M	Pretoxin HINT domain	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT
LZS3_k127_6946465_11	795359.TOPB45_0864	2.838e-58	217.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
LZS3_k127_6946465_10	795359.TOPB45_0865	2.975e-62	241.0	COG0419@1|root,COG0419@2|Bacteria,2GI5T@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	AAA domain	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	-
LZS3_k127_6946465_4	1191523.MROS_1891	8.51e-176	589.0	COG0729@1|root,COG0823@1|root,COG0729@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	treP	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,PD40
LZS3_k127_6957891_4	522772.Dacet_0072	1.123e-51	189.0	COG3808@1|root,COG3808@2|Bacteria,2GFAJ@200930|Deferribacteres	200930|Deferribacteres	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
LZS3_k127_6957891_6	35754.JNYJ01000013_gene1129	6.275e-47	176.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4D9KN@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
LZS3_k127_6957891_0	1265505.ATUG01000002_gene1825	1.866e-118	393.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,2MI2R@213118|Desulfobacterales	28221|Deltaproteobacteria	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
LZS3_k127_6957891_1	1089550.ATTH01000002_gene87	4.423e-103	349.0	COG1668@1|root,COG1668@2|Bacteria,4NMG0@976|Bacteroidetes	976|Bacteroidetes	CP	ABC-2 family transporter protein	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3
LZS3_k127_6957891_2	1089550.ATTH01000002_gene88	3.687e-102	349.0	COG4555@1|root,COG4555@2|Bacteria,4PNSV@976|Bacteroidetes	976|Bacteroidetes	CP	ATPases associated with a variety of cellular activities	-	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
LZS3_k127_6957891_7	498211.CJA_2651	1.49e-23	104.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria,1FHIZ@10|Cellvibrio	1236|Gammaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
LZS3_k127_6957891_9	880073.Calab_2214	1.425e-19	102.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	-
LZS3_k127_6957891_3	1123234.AUKI01000013_gene1581	2.255e-58	219.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
LZS3_k127_6957891_10	880073.Calab_3296	6e-14	85.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
LZS3_k127_6957891_5	1123234.AUKI01000013_gene1581	7.798e-51	201.0	COG5276@1|root,COG5276@2|Bacteria,4NDUD@976|Bacteroidetes,1HZ43@117743|Flavobacteriia	976|Bacteroidetes	O	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LVIVD,MAM,TSP_3,fn3
LZS3_k127_6957891_8	880073.Calab_2081	3.318e-21	100.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_6972917_23	880073.Calab_0921	9.416e-22	112.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_6972917_5	880073.Calab_1003	2.105e-113	381.0	COG1301@1|root,COG1301@2|Bacteria,2NP6X@2323|unclassified Bacteria	2|Bacteria	U	Sodium:dicarboxylate symporter family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
LZS3_k127_6972917_6	1173024.KI912149_gene6100	9.751e-88	305.0	COG0438@1|root,COG0438@2|Bacteria,1G13Y@1117|Cyanobacteria,1JJN1@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
LZS3_k127_6972917_4	118168.MC7420_1754	3.033e-115	388.0	COG3379@1|root,COG3379@2|Bacteria,1G44K@1117|Cyanobacteria,1HD9A@1150|Oscillatoriales	1117|Cyanobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
LZS3_k127_6972917_24	373903.Hore_17680	3.384e-19	101.0	COG4775@1|root,COG4775@2|Bacteria,1UMDS@1239|Firmicutes,24F0X@186801|Clostridia,3WAA6@53433|Halanaerobiales	186801|Clostridia	M	PFAM Surface antigen variable number repeat	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
LZS3_k127_6972917_18	1286632.P278_29800	2.817e-35	151.0	COG2067@1|root,COG2067@2|Bacteria,4NRUP@976|Bacteroidetes,1I6RT@117743|Flavobacteriia	976|Bacteroidetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6972917_22	478741.JAFS01000001_gene2025	1.996e-23	106.0	2AG8J@1|root,316DU@2|Bacteria,46WFQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6972917_13	264732.Moth_0883	1.192e-55	205.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,42G12@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
LZS3_k127_6972917_0	1121015.N789_13410	3.074e-248	774.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,1RM8P@1236|Gammaproteobacteria,1X3CQ@135614|Xanthomonadales	135614|Xanthomonadales	E	Transporter	yhiP	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
LZS3_k127_6972917_20	1267533.KB906737_gene1998	4.447e-31	130.0	2E3FB@1|root,32YE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6972917_14	1042326.AZNV01000004_gene4029	5.895e-52	191.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,4BCYP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
LZS3_k127_6972917_8	1307759.JOMJ01000003_gene372	7.372e-73	261.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2M8K5@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
LZS3_k127_6972917_17	555088.DealDRAFT_1074	6.382e-40	164.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,42K0H@68298|Syntrophomonadaceae	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
LZS3_k127_6972917_29	1121930.AQXG01000012_gene3205	6.708e-08	65.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1IPPH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
LZS3_k127_6972917_3	243231.GSU1272	2.261e-119	408.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,43TM6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
LZS3_k127_6972917_2	1379698.RBG1_1C00001G1495	1.217e-121	399.0	COG0540@1|root,COG0540@2|Bacteria,2NNPZ@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490	OTCace,OTCace_N
LZS3_k127_6972917_10	477974.Daud_1306	7.647e-66	234.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,261GH@186807|Peptococcaceae	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
LZS3_k127_6972917_28	301.JNHE01000008_gene3732	6.32e-08	63.0	COG1670@1|root,COG1670@2|Bacteria,1RKKE@1224|Proteobacteria,1S47R@1236|Gammaproteobacteria,1YGH7@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
LZS3_k127_6972917_21	290397.Adeh_4128	3.152e-24	116.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS3_k127_6972917_15	1519464.HY22_02720	8.005e-50	185.0	COG0546@1|root,COG0546@2|Bacteria,1FDVN@1090|Chlorobi	1090|Chlorobi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
LZS3_k127_6972917_1	452637.Oter_3899	1.475e-179	588.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,46UA9@74201|Verrucomicrobia,3K7MZ@414999|Opitutae	414999|Opitutae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
LZS3_k127_6972917_19	861299.J421_4358	5.14e-35	144.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_6972917_16	861299.J421_4357	9.065e-50	194.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_6972917_9	1379270.AUXF01000001_gene2652	9.064e-70	242.0	COG1136@1|root,COG1136@2|Bacteria,1ZUKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_6972917_12	1379270.AUXF01000001_gene2653	2.598e-56	216.0	2AETJ@1|root,314QN@2|Bacteria,1ZU8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6972917_7	1380390.JIAT01000013_gene213	2.064e-87	317.0	COG3325@1|root,COG3325@2|Bacteria,2IGIW@201174|Actinobacteria,4CPKA@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6972917_25	395494.Galf_2212	8.603e-15	80.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,44WIE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
LZS3_k127_6972917_26	1123393.KB891333_gene2536	1.002e-13	76.0	COG5393@1|root,COG5393@2|Bacteria,1NDFU@1224|Proteobacteria,2VX3I@28216|Betaproteobacteria,1KRW7@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
LZS3_k127_6972917_30	589924.Ferp_1117	3.453e-07	60.0	arCOG11830@1|root,arCOG11830@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_6972917_27	880073.Calab_0035	6.988e-12	79.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FlgD_ig,SLH
LZS3_k127_6972917_11	1254432.SCE1572_50715	2.946e-65	247.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_6972917_31	459349.CLOAM1572	3.416e-06	57.0	COG2273@1|root,COG2356@1|root,COG2374@1|root,COG4412@1|root,COG2273@2|Bacteria,COG2356@2|Bacteria,COG2374@2|Bacteria,COG4412@2|Bacteria,2NR8S@2323|unclassified Bacteria	2|Bacteria	GL	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K07004,ko:K09955	-	-	-	-	ko00000	-	-	-	DUF1524,FTP,LTD,PA,Peptidase_M36
LZS3_k127_7034339_2	1120934.KB894435_gene4455	2.782e-74	258.0	COG0520@1|root,COG0520@2|Bacteria,2GN15@201174|Actinobacteria,4E19E@85010|Pseudonocardiales	201174|Actinobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
LZS3_k127_7034339_1	1128421.JAGA01000002_gene1518	9.502e-102	336.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
LZS3_k127_7034339_0	330214.NIDE2454	6.407e-177	565.0	COG0114@1|root,COG0114@2|Bacteria,3J0FU@40117|Nitrospirae	40117|Nitrospirae	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
LZS3_k127_7034339_3	309807.SRU_2180	8.793e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,4PEIW@976|Bacteroidetes,1FJ6Z@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7170035_0	269797.Mbar_A0416	2.042e-98	329.0	arCOG03561@1|root,arCOG03561@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
LZS3_k127_7170035_4	945713.IALB_1719	1.747e-16	94.0	COG1404@1|root,COG4409@1|root,COG1404@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,CelD_N,FlgD_ig,Glyco_hydro_9,VCBS
LZS3_k127_7170035_1	247490.KSU1_C0449	3.214e-96	339.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_7170035_3	1047013.AQSP01000033_gene1392	2.346e-29	128.0	2B0BZ@1|root,31SP3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7170035_2	1254432.SCE1572_29505	1.478e-48	189.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,42WBG@68525|delta/epsilon subdivisions,2WS3Q@28221|Deltaproteobacteria,2YY0X@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
LZS3_k127_7218558_2	997346.HMPREF9374_1798	7.749e-145	469.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,27AW4@186824|Thermoactinomycetaceae	91061|Bacilli	J	tRNA synthetases class I (W and Y)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
LZS3_k127_7218558_0	1379698.RBG1_1C00001G1562	4.702e-173	568.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
LZS3_k127_7218558_11	1463853.JOHW01000001_gene6084	8.448e-42	166.0	COG1309@1|root,COG1309@2|Bacteria,2GPBQ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_7218558_1	105559.Nwat_0066	1.748e-150	486.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria,1X18G@135613|Chromatiales	135613|Chromatiales	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
LZS3_k127_7218558_3	370438.PTH_1211	6.487e-127	417.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,260HR@186807|Peptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
LZS3_k127_7218558_8	555088.DealDRAFT_0283	8.066e-82	286.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,42JHX@68298|Syntrophomonadaceae	186801|Clostridia	H	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
LZS3_k127_7218558_10	237368.SCABRO_01223	8.771e-53	204.0	COG0737@1|root,COG0737@2|Bacteria,2IXWK@203682|Planctomycetes	203682|Planctomycetes	C	5'-nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
LZS3_k127_7218558_14	880073.Calab_2402	3.817e-39	168.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7218558_12	880073.Calab_2402	1.935e-41	176.0	28KE7@1|root,2ZA0G@2|Bacteria,2NPZB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7218558_13	404589.Anae109_2378	3.142e-40	166.0	COG0642@1|root,COG2205@2|Bacteria	404589.Anae109_2378|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7218558_5	398767.Glov_3076	3.448e-113	383.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43TS4@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_7218558_7	760568.Desku_0806	6.065e-82	287.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
LZS3_k127_7218558_9	56780.SYN_02636	8.077e-71	248.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2MQGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
LZS3_k127_7218558_4	671143.DAMO_0645	4.546e-123	407.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
LZS3_k127_7218558_15	945713.IALB_0147	5.157e-20	108.0	COG2234@1|root,COG4412@1|root,COG2234@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.11.10,3.4.21.50	ko:K01337,ko:K05994,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,Glyco_hydro_31,PA,Peptidase_M28,Peptidase_M6,Peptidase_S8,W_rich_C
LZS3_k127_7218558_6	997884.HMPREF1068_00362	3.642e-97	362.0	COG1361@1|root,COG1520@1|root,COG4870@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia,4ATRZ@815|Bacteroidaceae	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
LZS3_k127_7218558_17	1089550.ATTH01000001_gene1531	3.62e-15	76.0	COG2911@1|root,COG3210@1|root,COG3391@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,4NTNN@976|Bacteroidetes	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
LZS3_k127_725871_2	472759.Nhal_1456	2.471e-206	649.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1WWTW@135613|Chromatiales	135613|Chromatiales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
LZS3_k127_725871_41	862908.BMS_1350	4.587e-05	56.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,42SUC@68525|delta/epsilon subdivisions,2MTWH@213481|Bdellovibrionales,2WPR4@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	PFAM lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
LZS3_k127_725871_20	246197.MXAN_4007	4.233e-65	248.0	COG3637@1|root,COG3637@2|Bacteria,1QXUM@1224|Proteobacteria	1224|Proteobacteria	M	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
LZS3_k127_725871_0	314230.DSM3645_11037	0.0	1174.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2IXY9@203682|Planctomycetes	203682|Planctomycetes	C	Acyl-CoA synthetase (NDP forming)	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
LZS3_k127_725871_10	926550.CLDAP_22570	2.114e-135	440.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
LZS3_k127_725871_1	234267.Acid_3259	2.735e-285	893.0	COG1297@1|root,COG1297@2|Bacteria,3Y3SD@57723|Acidobacteria	57723|Acidobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
LZS3_k127_725871_4	497964.CfE428DRAFT_5240	5.972e-146	467.0	COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
LZS3_k127_725871_23	1121403.AUCV01000003_gene1784	4.413e-52	204.0	COG5607@1|root,COG5607@2|Bacteria,1NGVB@1224|Proteobacteria,42X7Z@68525|delta/epsilon subdivisions,2WSMB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CHAD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
LZS3_k127_725871_29	1267534.KB906760_gene1554	2.148e-24	106.0	2DD3Z@1|root,2ZGDH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_725871_26	1122176.KB903561_gene3594	1.618e-41	163.0	COG0671@1|root,COG0671@2|Bacteria,4NP4B@976|Bacteroidetes,1ISII@117747|Sphingobacteriia	976|Bacteroidetes	I	Phosphatidic acid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
LZS3_k127_725871_14	1232410.KI421415_gene3102	2.824e-103	347.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,43S1P@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
LZS3_k127_725871_7	638303.Thal_1002	2.234e-138	462.0	COG0635@1|root,COG0635@2|Bacteria,2G4M1@200783|Aquificae	200783|Aquificae	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
LZS3_k127_725871_16	1210884.HG799470_gene14277	7.499e-83	293.0	COG1232@1|root,COG1232@2|Bacteria,2IWT1@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
LZS3_k127_725871_30	1519464.HY22_11790	1.141e-23	113.0	COG0276@1|root,COG0276@2|Bacteria	2|Bacteria	H	ferrochelatase activity	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
LZS3_k127_725871_19	1125863.JAFN01000001_gene1123	2.066e-76	272.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
LZS3_k127_725871_18	1444309.JAQG01000075_gene140	3.082e-77	280.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,26RBP@186822|Paenibacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
LZS3_k127_725871_6	1122223.KB890688_gene1418	1.019e-139	458.0	COG0113@1|root,COG0113@2|Bacteria,1WINH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
LZS3_k127_725871_3	383372.Rcas_2033	1.525e-169	542.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,374V4@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
LZS3_k127_725871_35	518766.Rmar_1453	1.238e-15	87.0	COG1366@1|root,COG1366@2|Bacteria,4NTNE@976|Bacteroidetes	976|Bacteroidetes	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
LZS3_k127_725871_32	1096769.Pelub83DRAFT_0415	3.44e-20	93.0	2FDFA@1|root,345GY@2|Bacteria,1P1RR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_725871_24	42256.RradSPS_0950	1.301e-44	168.0	COG1755@1|root,COG1755@2|Bacteria,2IG52@201174|Actinobacteria	201174|Actinobacteria	S	Isoprenylcysteine carboxyl methyltransferase	srsB	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
LZS3_k127_725871_13	649747.HMPREF0083_02105	2.501e-103	347.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,26VEY@186822|Paenibacillaceae	91061|Bacilli	Q	synthase	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
LZS3_k127_725871_11	945713.IALB_2321	2.153e-114	407.0	COG0308@1|root,COG0308@2|Bacteria	2|Bacteria	E	peptide catabolic process	pepN1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
LZS3_k127_725871_5	293826.Amet_4112	1.258e-140	458.0	COG0031@1|root,COG0031@2|Bacteria,1UZEQ@1239|Firmicutes,24BCR@186801|Clostridia,36G6F@31979|Clostridiaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
LZS3_k127_725871_21	530564.Psta_4128	1.41e-61	219.0	COG0225@1|root,COG0225@2|Bacteria,2IZ67@203682|Planctomycetes	203682|Planctomycetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
LZS3_k127_725871_27	290397.Adeh_3342	9.905e-40	169.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
LZS3_k127_725871_12	404589.Anae109_3404	6.67e-104	359.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YUPC@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	crdA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_725871_33	452637.Oter_1350	1.98e-19	100.0	COG0457@1|root,COG0457@2|Bacteria,46Y0G@74201|Verrucomicrobia,3K8R1@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_725871_28	1340493.JNIF01000002_gene1239	2.009e-32	146.0	COG0726@1|root,COG0726@2|Bacteria,3Y5MF@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
LZS3_k127_725871_39	1385514.N782_00030	1.909e-10	73.0	COG3153@1|root,COG3153@2|Bacteria,1V0I4@1239|Firmicutes,4HCMH@91061|Bacilli,2YB6D@289201|Pontibacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
LZS3_k127_725871_8	522306.CAP2UW1_0198	5.232e-138	447.0	COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,2VN83@28216|Betaproteobacteria	28216|Betaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
LZS3_k127_725871_22	562970.Btus_1426	3.8e-54	212.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,277VY@186823|Alicyclobacillaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS3_k127_725871_34	204669.Acid345_4329	9.726e-18	96.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,GGDEF,Trans_reg_C,Yop-YscD_cpl
LZS3_k127_725871_15	485913.Krac_4124	8.262e-100	347.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
LZS3_k127_725871_17	211114.JOEF01000034_gene1389	4.419e-78	271.0	COG0702@1|root,COG0702@2|Bacteria,2GK71@201174|Actinobacteria,4E5U1@85010|Pseudonocardiales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
LZS3_k127_725871_25	1519464.HY22_02020	3.395e-43	160.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	yurZ	-	2.3.1.12,4.1.1.44	ko:K00627,ko:K01607	ko00010,ko00020,ko00362,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00020,map00362,map00620,map01100,map01110,map01120,map01130,map01200,map01220	M00307	R00209,R02569,R03470	RC00004,RC00938,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CMD
LZS3_k127_725871_9	1279009.ADICEAN_04046	1.969e-137	445.0	COG0535@1|root,COG0535@2|Bacteria,4NFRX@976|Bacteroidetes,47KUF@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
LZS3_k127_725871_42	545695.TREAZ_3555	0.0001891	53.0	COG2885@1|root,COG2885@2|Bacteria,2J5KD@203691|Spirochaetes	203691|Spirochaetes	M	ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,CHU_C,FlgD_ig,OmpA
LZS3_k127_725871_40	314282.PCNPT3_12075	1.587e-05	57.0	COG0810@1|root,COG0810@2|Bacteria,1NH16@1224|Proteobacteria	1224|Proteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
LZS3_k127_725871_37	1122613.ATUP01000001_gene943	1.644e-12	73.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,43YA5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	U	ExbD TolR family transport energizing protein	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS3_k127_725871_38	316057.RPD_3332	6.352e-11	68.0	COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,2U77T@28211|Alphaproteobacteria,3JZ71@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	Outer membrane transport energization protein ExbD	exbD	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
LZS3_k127_725871_31	1123368.AUIS01000016_gene2523	5.975e-21	107.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,2NCJP@225057|Acidithiobacillales	225057|Acidithiobacillales	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
LZS3_k127_725871_36	1305737.JAFX01000001_gene851	3.224e-14	87.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,47JS4@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
LZS3_k127_7422424_21	880073.Calab_2214	6.795e-09	67.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	-
LZS3_k127_7422424_25	7227.FBpp0293691	0.0008219	51.0	KOG3509@1|root,KOG3509@2759|Eukaryota,38X54@33154|Opisthokonta,3B9Y9@33208|Metazoa,3CYVU@33213|Bilateria,41VR7@6656|Arthropoda,3SFYU@50557|Insecta,44Y5Y@7147|Diptera,45R9A@7214|Drosophilidae	33208|Metazoa	T	Laminin B domain	HSPG2	GO:0000323,GO:0000902,GO:0000904,GO:0001523,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005604,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005775,GO:0005794,GO:0005796,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006026,GO:0006027,GO:0006629,GO:0006720,GO:0006721,GO:0006807,GO:0006810,GO:0006897,GO:0006898,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006954,GO:0007163,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007414,GO:0007415,GO:0007417,GO:0007420,GO:0008022,GO:0008037,GO:0008038,GO:0008045,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009605,GO:0009653,GO:0009892,GO:0009966,GO:0009967,GO:0009987,GO:0010605,GO:0010646,GO:0010647,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0016101,GO:0016192,GO:0016525,GO:0019222,GO:0019538,GO:0022008,GO:0022603,GO:0023051,GO:0023056,GO:0030011,GO:0030030,GO:0030154,GO:0030182,GO:0030198,GO:0030203,GO:0031012,GO:0031175,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0032991,GO:0035088,GO:0035090,GO:0040011,GO:0042221,GO:0042330,GO:0042493,GO:0043062,GO:0043170,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044255,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045197,GO:0045199,GO:0045765,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050750,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050896,GO:0051093,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051246,GO:0051248,GO:0060255,GO:0060322,GO:0060548,GO:0061245,GO:0061564,GO:0062023,GO:0065007,GO:0070013,GO:0070325,GO:0071704,GO:0071840,GO:0071944,GO:0072347,GO:0072358,GO:0072359,GO:0080090,GO:0097485,GO:0098657,GO:0098796,GO:0098797,GO:0120036,GO:0120039,GO:1901135,GO:1901136,GO:1901137,GO:1901342,GO:1901343,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1902903,GO:1902904,GO:1905906,GO:1905907,GO:2000026,GO:2000181,GO:2001260,GO:2001262	-	ko:K06255	ko04512,ko05161,ko05205,map04512,map05161,map05205	-	-	-	ko00000,ko00001,ko00535,ko04147,ko04516	-	-	-	EGF,I-set,Ig_3,Laminin_B,Laminin_EGF,Laminin_G_1,Laminin_G_2,Ldl_recept_a,ig
LZS3_k127_7422424_4	452637.Oter_2424	5.945e-108	383.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_7422424_3	273068.TTE1263	3.131e-111	371.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,42F4T@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS3_k127_7422424_13	331678.Cphamn1_0650	9.727e-31	130.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
LZS3_k127_7422424_11	485916.Dtox_3084	7.023e-44	181.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,260UH@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K10681	ko02020,map02020	M00468	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
LZS3_k127_7422424_16	945713.IALB_2396	6.079e-19	104.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Sortilin-Vps10
LZS3_k127_7422424_1	1121104.AQXH01000001_gene1413	4.071e-202	667.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPZZ@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_7422424_0	1385517.N800_09225	1.362e-263	848.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1X3PQ@135614|Xanthomonadales	135614|Xanthomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
LZS3_k127_7422424_9	1121104.AQXH01000001_gene1411	2.208e-49	192.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
LZS3_k127_7422424_24	1047013.AQSP01000142_gene167	0.0003676	52.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	ywhL	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
LZS3_k127_7422424_8	96561.Dole_1802	6.541e-60	221.0	COG0438@1|root,COG0438@2|Bacteria,1RCC7@1224|Proteobacteria,42YR8@68525|delta/epsilon subdivisions,2WTJB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7422424_23	880073.Calab_2700	4.305e-05	55.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
LZS3_k127_7422424_6	864563.HMPREF9166_0037	5.908e-73	271.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4H2P5@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
LZS3_k127_7422424_19	1123325.JHUV01000009_gene412	6.261e-13	81.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2G407@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
LZS3_k127_7422424_18	1124982.MSI_22010	7.607e-14	81.0	COG0457@1|root,COG0457@2|Bacteria,2J58Z@203691|Spirochaetes	203691|Spirochaetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8
LZS3_k127_7422424_20	1121895.Q765_03380	1.032e-11	78.0	COG2067@1|root,COG2067@2|Bacteria,4NEP1@976|Bacteroidetes,1HXXP@117743|Flavobacteriia,2NS6K@237|Flavobacterium	976|Bacteroidetes	I	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7422424_17	639282.DEFDS_1264	1.073e-18	90.0	COG0848@1|root,COG0848@2|Bacteria,2GFX6@200930|Deferribacteres	200930|Deferribacteres	U	Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
LZS3_k127_7422424_10	880073.Calab_1219	2.09e-44	168.0	COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB2	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
LZS3_k127_7422424_15	880073.Calab_1220	2.05e-20	102.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	tonB3	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
LZS3_k127_7422424_12	1203606.HMPREF1526_00005	4.455e-35	147.0	COG0500@1|root,COG2226@2|Bacteria,1TR7I@1239|Firmicutes,24FG4@186801|Clostridia	186801|Clostridia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
LZS3_k127_7422424_5	381764.Fnod_0163	6.667e-101	341.0	COG3842@1|root,COG3842@2|Bacteria,2GC81@200918|Thermotogae	200918|Thermotogae	P	ABC transporter	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE
LZS3_k127_7422424_2	1191523.MROS_2755	3.702e-161	520.0	COG0160@1|root,COG0160@2|Bacteria	2|Bacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lat	-	2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36	ko:K00821,ko:K03918,ko:K07250,ko:K13524	ko00220,ko00250,ko00280,ko00300,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,ko04727,map00220,map00250,map00280,map00300,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01210,map01230,map04727	M00016,M00027,M00028,M00845	R00457,R00908,R01648,R02283,R04188,R04475	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv3290c	Aminotran_3
LZS3_k127_7422424_7	348780.NP_2420A	5.718e-68	250.0	COG1574@1|root,arCOG00691@2157|Archaea,2XUUZ@28890|Euryarchaeota,23SFX@183963|Halobacteria	183963|Halobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
LZS3_k127_7422424_14	880073.Calab_3359	2.507e-25	116.0	COG4632@1|root,COG4632@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Metallophos,NAGPA,Polysacc_deac_1,SLH
LZS3_k127_7444742_1	1336241.JAEB01000014_gene2020	3.467e-64	231.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,24818@186801|Clostridia,25ZNP@186806|Eubacteriaceae	186801|Clostridia	M	RmlD substrate binding domain	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS3_k127_7444742_0	717606.PaecuDRAFT_4483	4.608e-133	431.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4HF5Y@91061|Bacilli,275YJ@186822|Paenibacillaceae	91061|Bacilli	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
LZS3_k127_765038_26	404589.Anae109_4144	0.0001007	50.0	COG0457@1|root,COG0457@2|Bacteria,1RJUD@1224|Proteobacteria,42P27@68525|delta/epsilon subdivisions,2WK9Y@28221|Deltaproteobacteria,2Z2Z5@29|Myxococcales	28221|Deltaproteobacteria	PT	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_8,TonB_dep_Rec,zinc_ribbon_4
LZS3_k127_765038_10	1144275.COCOR_07790	5.912e-78	285.0	COG3291@1|root,COG3291@2|Bacteria,1NE5Q@1224|Proteobacteria,433YB@68525|delta/epsilon subdivisions,2X423@28221|Deltaproteobacteria,2YY0M@29|Myxococcales	28221|Deltaproteobacteria	S	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M43
LZS3_k127_765038_16	1122176.KB903570_gene4799	2.745e-37	161.0	COG3227@1|root,COG4935@1|root,COG3227@2|Bacteria,COG4935@2|Bacteria,4PPGZ@976|Bacteroidetes	976|Bacteroidetes	O	Metallo-peptidase family M12	-	-	-	-	-	-	-	-	-	-	-	-	CUB,Reprolysin_5
LZS3_k127_765038_20	1519464.HY22_13055	5.258e-19	102.0	COG0265@1|root,COG0366@1|root,COG0265@2|Bacteria,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Alpha-amylase
LZS3_k127_765038_22	755732.Fluta_0658	4.908e-15	84.0	COG3137@1|root,COG3137@2|Bacteria,4NJH6@976|Bacteroidetes,1IEQS@117743|Flavobacteriia,2PB3G@246874|Cryomorphaceae	976|Bacteroidetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
LZS3_k127_765038_4	502025.Hoch_5285	4.156e-112	386.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42MQV@68525|delta/epsilon subdivisions,2X1WZ@28221|Deltaproteobacteria,2YZ4N@29|Myxococcales	28221|Deltaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
LZS3_k127_765038_13	1027273.GZ77_15620	1.744e-60	215.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1XJ7K@135619|Oceanospirillales	135619|Oceanospirillales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
LZS3_k127_765038_15	1123367.C666_12290	1.17e-54	211.0	COG2202@1|root,COG3452@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3452@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,2KUQP@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9
LZS3_k127_765038_24	342113.DM82_6250	2.203e-07	61.0	COG2823@1|root,COG2823@2|Bacteria,1N8H9@1224|Proteobacteria,2VXHG@28216|Betaproteobacteria,1K7BQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	-	-	-	-	-	-	-	-	-	BON
LZS3_k127_765038_21	644282.Deba_1750	1.776e-17	92.0	COG0745@1|root,COG0745@2|Bacteria,1RINR@1224|Proteobacteria,42T1R@68525|delta/epsilon subdivisions,2WPHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_765038_12	644282.Deba_1749	4.908e-67	245.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
LZS3_k127_765038_19	1499967.BAYZ01000059_gene4769	4.162e-23	105.0	COG0745@1|root,COG0745@2|Bacteria,2NRCE@2323|unclassified Bacteria	2|Bacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
LZS3_k127_765038_9	156889.Mmc1_0881	5.728e-87	303.0	COG0479@1|root,COG0479@2|Bacteria,1QVWG@1224|Proteobacteria,2TWVH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
LZS3_k127_765038_7	648996.Theam_0486	2.079e-92	312.0	COG0543@1|root,COG0543@2|Bacteria,2G45B@200783|Aquificae	200783|Aquificae	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
LZS3_k127_765038_14	404380.Gbem_1969	6.475e-59	213.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42U69@68525|delta/epsilon subdivisions,2WQJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase 20 kDa subunit	hyhS	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
LZS3_k127_765038_6	374847.Kcr_0321	2.828e-93	325.0	COG0374@1|root,arCOG01549@2157|Archaea	2157|Archaea	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hydA	GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494	1.12.1.3,1.12.1.5,1.8.98.5	ko:K14126,ko:K17993	ko00680,ko00920,map00680,map00920	-	R00019,R10390,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
LZS3_k127_765038_5	243231.GSU0775	7.661e-99	347.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
LZS3_k127_765038_23	767817.Desgi_1167	2.045e-09	67.0	COG0680@1|root,COG0680@2|Bacteria,1V7KQ@1239|Firmicutes,24IHW@186801|Clostridia	186801|Clostridia	C	hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
LZS3_k127_765038_18	1121378.KB899773_gene622	1.06e-25	123.0	28HH2@1|root,33750@2|Bacteria	2|Bacteria	M	Thiol-activated cytolysin	-	-	-	ko:K11031	ko02024,map02024	-	-	-	ko00000,ko00001,ko02042	-	-	-	Thiol_cytolysin
LZS3_k127_765038_1	338966.Ppro_1915	2.635e-193	615.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKE@68525|delta/epsilon subdivisions,2WJTK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_765038_3	338966.Ppro_1917	1.155e-134	432.0	COG1136@1|root,COG1136@2|Bacteria,1MXVW@1224|Proteobacteria,42MKV@68525|delta/epsilon subdivisions,2WJJT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_765038_0	76114.ebA6251	6.124e-220	688.0	COG0577@1|root,COG0577@2|Bacteria,1MVSU@1224|Proteobacteria,2VKTK@28216|Betaproteobacteria,2KY30@206389|Rhodocyclales	206389|Rhodocyclales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
LZS3_k127_765038_2	1123054.KB907744_gene3527	1.113e-173	552.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria,1WX86@135613|Chromatiales	135613|Chromatiales	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3,OEP
LZS3_k127_765038_8	76114.ebA6247	5.125e-90	300.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VMVD@28216|Betaproteobacteria,2KY5C@206389|Rhodocyclales	206389|Rhodocyclales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
LZS3_k127_765038_11	338969.Rfer_4150	2.632e-69	243.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,2W3U8@28216|Betaproteobacteria,4AI76@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_765038_17	1459636.NTE_03410	9.522e-28	114.0	COG3945@1|root,arCOG01471@2157|Archaea	2157|Archaea	S	Hemerythrin HHE cation binding	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,PRC,ScdA_N
LZS3_k127_7694484_2	880073.Calab_0537	5.087e-235	737.0	COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria	2|Bacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
LZS3_k127_7694484_10	867903.ThesuDRAFT_02291	3.039e-29	121.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3WCMW@538999|Clostridiales incertae sedis	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
LZS3_k127_7694484_11	309801.trd_1062	2.183e-14	82.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi,27Y5M@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	-	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
LZS3_k127_7694484_6	1121430.JMLG01000037_gene140	2.608e-43	169.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,260CI@186807|Peptococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
LZS3_k127_7694484_4	1379270.AUXF01000002_gene1769	4.424e-55	210.0	COG0157@1|root,COG0157@2|Bacteria,1ZSR4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Quinolinate phosphoribosyl transferase, C-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
LZS3_k127_7694484_1	880073.Calab_3212	4.999e-261	828.0	COG0556@1|root,COG0556@2|Bacteria,2NNPM@2323|unclassified Bacteria	2|Bacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
LZS3_k127_7694484_12	754027.HMPREF9554_01266	1.376e-10	68.0	COG1426@1|root,COG1426@2|Bacteria,2J61E@203691|Spirochaetes	203691|Spirochaetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
LZS3_k127_7694484_0	1123371.ATXH01000005_gene2143	1.804e-286	906.0	COG0525@1|root,COG0525@2|Bacteria,2GGVS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
LZS3_k127_7694484_7	309807.SRU_0100	4.509e-41	166.0	COG0823@1|root,COG0823@2|Bacteria,4NITC@976|Bacteroidetes	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
LZS3_k127_7694484_3	945713.IALB_1280	1.83e-95	331.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	GSDH,SGL
LZS3_k127_7694484_8	406552.NJ7G_3597	3.128e-34	142.0	COG0382@1|root,arCOG00476@2157|Archaea,2XUHS@28890|Euryarchaeota,23SVZ@183963|Halobacteria	183963|Halobacteria	I	Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids	ubiA2	-	2.5.1.42	ko:K17105	ko00564,map00564	-	R04520	RC01171	ko00000,ko00001,ko01000	-	-	-	UbiA
LZS3_k127_7694484_9	1173029.JH980292_gene2288	6.26e-32	139.0	COG0457@1|root,COG0457@2|Bacteria,1GD9N@1117|Cyanobacteria,1HH3D@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
LZS3_k127_7694484_5	1150626.PHAMO_380103	3.086e-52	196.0	COG5433@1|root,COG5433@2|Bacteria,1MY25@1224|Proteobacteria,2U0Y8@28211|Alphaproteobacteria,2JVFX@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
LZS3_k127_7758090_4	518766.Rmar_2521	1.211e-81	279.0	COG2234@1|root,COG2234@2|Bacteria,4NFDJ@976|Bacteroidetes,1FKC5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
LZS3_k127_7758090_12	1521187.JPIM01000010_gene2121	2.013e-05	57.0	COG1716@1|root,COG3391@1|root,COG4733@1|root,COG1716@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	2.7.11.1,3.2.1.78	ko:K01218,ko:K12132	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01001	-	GH26	-	FHA,NHL,fn3
LZS3_k127_7758090_2	215803.DB30_8173	2.945e-212	672.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria,2YUS1@29|Myxococcales	28221|Deltaproteobacteria	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
LZS3_k127_7758090_3	1379698.RBG1_1C00001G1677	5.391e-127	416.0	COG3239@1|root,COG3239@2|Bacteria,2NNTZ@2323|unclassified Bacteria	2|Bacteria	I	Fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
LZS3_k127_7758090_7	404589.Anae109_3198	1.009e-35	149.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS3_k127_7758090_11	1121285.AUFK01000010_gene1724	5.824e-06	57.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1HYN2@117743|Flavobacteriia,3ZQNW@59732|Chryseobacterium	976|Bacteroidetes	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
LZS3_k127_7758090_10	1379698.RBG1_1C00001G0678	9.114e-08	62.0	294GU@1|root,2ZRWK@2|Bacteria,2NRXQ@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7758090_0	1379698.RBG1_1C00001G0679	1.462e-231	731.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
LZS3_k127_7758090_1	690850.Desaf_0617	1.248e-213	691.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,2M7U6@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
LZS3_k127_7758090_5	65393.PCC7424_4033	7.208e-72	253.0	COG1600@1|root,COG1600@2|Bacteria,1G007@1117|Cyanobacteria,3KH9H@43988|Cyanothece	1117|Cyanobacteria	H	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
LZS3_k127_7758090_9	1191523.MROS_1616	9.231e-09	68.0	COG0457@1|root,COG0457@2|Bacteria	1191523.MROS_1616|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7758090_8	379066.GAU_1722	9.531e-24	117.0	COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
LZS3_k127_7758090_6	1379698.RBG1_1C00001G0230	5.873e-64	239.0	COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria	2|Bacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
LZS3_k127_7758156_3	1121441.AUCX01000023_gene1798	8.626e-61	222.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2M9X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
LZS3_k127_7758156_4	237368.SCABRO_01554	4.431e-55	211.0	COG1538@1|root,COG1538@2|Bacteria,2IZPU@203682|Planctomycetes	203682|Planctomycetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
LZS3_k127_7758156_7	234267.Acid_4231	2.555e-31	130.0	COG2332@1|root,COG2332@2|Bacteria,3Y57C@57723|Acidobacteria	57723|Acidobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
LZS3_k127_7758156_0	1382359.JIAL01000001_gene438	3.505e-190	615.0	COG1138@1|root,COG1138@2|Bacteria,3Y40N@57723|Acidobacteria,2JHQR@204432|Acidobacteriia	204432|Acidobacteriia	O	PFAM Cytochrome c assembly protein	-	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
LZS3_k127_7758156_11	635013.TherJR_2281	2.259e-11	77.0	COG3088@1|root,COG3088@2|Bacteria,1VETA@1239|Firmicutes,24TPT@186801|Clostridia,265EA@186807|Peptococcaceae	186801|Clostridia	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
LZS3_k127_7758156_13	682795.AciX8_3190	0.0003237	50.0	2EFR0@1|root,339H2@2|Bacteria,3Y5M9@57723|Acidobacteria,2JJPZ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7758156_10	926550.CLDAP_38270	8.83e-13	81.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
LZS3_k127_7758156_5	1382306.JNIM01000001_gene130	2.603e-47	184.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
LZS3_k127_7758156_6	552811.Dehly_0439	8.183e-44	174.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
LZS3_k127_7758156_2	1499967.BAYZ01000030_gene1163	9.195e-67	239.0	COG0755@1|root,COG0755@2|Bacteria,2NPG8@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmC	GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	iECDH1ME8569_1439.ECDH1ME8569_2134,iSFV_1184.SFV_2275,iSFxv_1172.SFxv_2517,iUTI89_1310.UTI89_C2477,ic_1306.c2736	Cytochrom_C_asm
LZS3_k127_7758156_8	555779.Dthio_PD1771	2.472e-25	109.0	COG3514@1|root,COG3514@2|Bacteria,1NAV1@1224|Proteobacteria,42XPB@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin,CopG_antitoxin
LZS3_k127_7758156_12	886293.Sinac_1390	4.945e-05	55.0	COG1595@1|root,COG1595@2|Bacteria,2IZNR@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_7758156_1	929556.Solca_3257	1.704e-110	370.0	COG1446@1|root,COG1446@2|Bacteria,4NF1U@976|Bacteroidetes,1IQI3@117747|Sphingobacteriia	976|Bacteroidetes	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
LZS3_k127_7758156_9	324602.Caur_1013	3.637e-13	79.0	COG0664@1|root,COG2172@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2172@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,376A8@32061|Chloroflexia	32061|Chloroflexia	KT	SMART protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE,cNMP_binding
LZS3_k127_78185_25	1120936.KB907224_gene2658	1.755e-33	150.0	COG0515@1|root,COG0515@2|Bacteria,2GM6E@201174|Actinobacteria,4EIU2@85012|Streptosporangiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	pkaA	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
LZS3_k127_78185_0	1125863.JAFN01000001_gene3129	0.0	1112.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
LZS3_k127_78185_20	926550.CLDAP_17040	9.558e-46	190.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
LZS3_k127_78185_16	794903.OPIT5_16825	1.437e-56	205.0	COG1853@1|root,COG1853@2|Bacteria,46TTE@74201|Verrucomicrobia,3K947@414999|Opitutae	414999|Opitutae	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
LZS3_k127_78185_9	1218108.KB908291_gene941	1.593e-133	436.0	COG3508@1|root,COG3508@2|Bacteria,4NEYZ@976|Bacteroidetes,1HYHK@117743|Flavobacteriia	976|Bacteroidetes	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
LZS3_k127_78185_29	945713.IALB_2311	5.08e-17	95.0	COG1409@1|root,COG2382@1|root,COG2885@1|root,COG1409@2|Bacteria,COG2382@2|Bacteria,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	3.1.4.53,5.2.1.8	ko:K03651,ko:K03771,ko:K07017	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000,ko03110	-	-	-	DUF3575,Esterase,Metallophos,OmpA,PD40,Rotamase,Rotamase_3
LZS3_k127_78185_19	377629.TERTU_3103	5.159e-46	187.0	COG3379@1|root,COG3379@2|Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfotransfer_1,TPR_16,TPR_19
LZS3_k127_78185_8	926559.JoomaDRAFT_1002	6.847e-137	444.0	COG3185@1|root,COG3185@2|Bacteria,4NFI7@976|Bacteroidetes,1HWZ3@117743|Flavobacteriia	976|Bacteroidetes	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
LZS3_k127_78185_3	768671.ThimaDRAFT_4172	3.777e-175	561.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales	135613|Chromatiales	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
LZS3_k127_78185_18	1267535.KB906767_gene347	3.85e-53	198.0	COG2159@1|root,COG2159@2|Bacteria,3Y6P0@57723|Acidobacteria	57723|Acidobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
LZS3_k127_78185_32	163908.KB235896_gene1029	2.15e-13	79.0	2BV24@1|root,32QEZ@2|Bacteria,1G6XJ@1117|Cyanobacteria,1HSKI@1161|Nostocales	1117|Cyanobacteria	S	TIGRFAM PEP-CTERM protein sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_78185_12	861299.J421_5977	2.206e-97	330.0	COG0665@1|root,COG0665@2|Bacteria,1ZUQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
LZS3_k127_78185_15	248742.XP_005647399.1	1.045e-76	280.0	COG0616@1|root,2QQH5@2759|Eukaryota,37JSU@33090|Viridiplantae,34JKR@3041|Chlorophyta	3041|Chlorophyta	OU	protease IV	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
LZS3_k127_78185_14	879212.DespoDRAFT_00589	3.873e-88	306.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria,2MI58@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
LZS3_k127_78185_30	926560.KE387023_gene3004	8.46e-14	85.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Big_2,Cadherin-like,Dockerin_1,Laminin_G_3,Lipase_GDSL_2,RCC1,SLH
LZS3_k127_78185_7	330214.NIDE2980	2.286e-141	456.0	COG1830@1|root,COG1830@2|Bacteria,3J1DE@40117|Nitrospirae	40117|Nitrospirae	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
LZS3_k127_78185_17	926569.ANT_22220	2.99e-56	202.0	COG2940@1|root,COG2940@2|Bacteria,2G9DE@200795|Chloroflexi	200795|Chloroflexi	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
LZS3_k127_78185_13	234267.Acid_7336	1.859e-96	334.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
LZS3_k127_78185_2	204669.Acid345_1270	1.278e-215	683.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
LZS3_k127_78185_11	204669.Acid345_1269	7.266e-122	403.0	COG0404@1|root,COG0404@2|Bacteria,3Y3IU@57723|Acidobacteria,2JI8G@204432|Acidobacteriia	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
LZS3_k127_78185_27	1379698.RBG1_1C00001G0764	8.672e-32	129.0	COG1959@1|root,COG1959@2|Bacteria,2NQ8B@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, BadM Rrf2 family	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
LZS3_k127_78185_26	243090.RB4742	3.018e-32	137.0	COG0589@1|root,COG0589@2|Bacteria,2J12B@203682|Planctomycetes	203682|Planctomycetes	T	COG0589 Universal stress protein UspA and related	-	-	-	ko:K14055	-	-	-	-	ko00000	-	-	-	Usp
LZS3_k127_78185_28	1191523.MROS_2770	1.174e-26	115.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp-3	-	-	-	-	-	-	-	-	-	-	-	Usp
LZS3_k127_78185_10	1384054.N790_14300	1.764e-130	443.0	COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,1RQA5@1236|Gammaproteobacteria,1X5QP@135614|Xanthomonadales	135614|Xanthomonadales	P	receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	Plug,TonB_dep_Rec
LZS3_k127_78185_6	880073.Calab_2261	5.032e-144	475.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2NNZ0@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
LZS3_k127_78185_1	344747.PM8797T_16213	1.637e-233	739.0	COG2217@1|root,COG2217@2|Bacteria,2IXE1@203682|Planctomycetes	203682|Planctomycetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
LZS3_k127_78185_21	1519464.HY22_09850	2.618e-41	158.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1,2.8.4.2,3.1.3.48	ko:K01104,ko:K03325,ko:K03741,ko:K03892,ko:K18701	-	-	-	-	ko00000,ko01000,ko02000,ko03000	2.A.59	-	-	LMWPc
LZS3_k127_78185_34	1519464.HY22_12835	2.31e-08	64.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
LZS3_k127_78185_5	391937.NA2_08766	9.664e-145	465.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,43NHA@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
LZS3_k127_78185_4	204669.Acid345_2395	7.75e-161	531.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
LZS3_k127_78185_31	1300345.LF41_2955	1.843e-13	78.0	2DEWU@1|root,2ZPJP@2|Bacteria,1P3DY@1224|Proteobacteria,1T86W@1236|Gammaproteobacteria,1XA81@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_78185_22	886293.Sinac_4818	3.274e-40	158.0	COG3832@1|root,COG3832@2|Bacteria,2IZKB@203682|Planctomycetes	203682|Planctomycetes	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
LZS3_k127_78185_23	234267.Acid_3366	1.377e-39	150.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20,HTH_5,Methyltransf_11
LZS3_k127_78185_24	670487.Ocepr_0471	8.749e-36	139.0	COG2318@1|root,COG2318@2|Bacteria,1WKI3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
LZS3_k127_7818639_5	768671.ThimaDRAFT_4485	7.808e-08	66.0	COG0265@1|root,COG1075@1|root,COG2304@1|root,COG0265@2|Bacteria,COG1075@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	MA20_07505	-	1.1.3.6,1.6.5.3,3.4.21.107	ko:K00337,ko:K03333,ko:K04771,ko:K07114	ko00190,ko00984,ko01100,ko01120,ko01503,ko02020,map00190,map00984,map01100,map01120,map01503,map02020	M00144,M00728	R01459,R11945	RC00061,RC00146	ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03110	1.A.13.2.2,1.A.13.2.3,3.D.1	-	-	DUF1194
LZS3_k127_7818639_0	760192.Halhy_2241	2.78e-31	142.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
LZS3_k127_7818639_1	517418.Ctha_1582	3.755e-26	128.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,F5_F8_type_C,SLH
LZS3_k127_7818639_2	945713.IALB_1293	7.554e-25	124.0	COG1523@1|root,COG4935@1|root,COG1523@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PUD,Reprolysin_4
LZS3_k127_7818639_3	1160718.SU9_24477	3.92e-24	122.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Lactonase,TIG
LZS3_k127_7818639_4	215803.DB30_6679	3.437e-19	97.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria,439MQ@68525|delta/epsilon subdivisions,2X4YU@28221|Deltaproteobacteria,2YZV4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7819163_1	1144275.COCOR_07663	6.529e-98	354.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria	1224|Proteobacteria	V	(ABC) transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_7819163_0	497964.CfE428DRAFT_2129	0.0	1343.0	COG0841@1|root,COG0841@2|Bacteria,46SDW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
LZS3_k127_7819163_2	452637.Oter_3803	3.915e-95	327.0	COG0845@1|root,COG0845@2|Bacteria,46U1B@74201|Verrucomicrobia,3K78A@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
LZS3_k127_7881535_35	1499967.BAYZ01000105_gene3517	1.736e-14	85.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	ChitinaseA_N,Lipase_GDSL_2
LZS3_k127_7881535_26	552811.Dehly_0404	5.549e-37	145.0	COG0454@1|root,COG0456@2|Bacteria,2GATN@200795|Chloroflexi,34DBC@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
LZS3_k127_7881535_12	290397.Adeh_1992	2.092e-84	297.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_7881535_32	861299.J421_2657	9.601e-28	130.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	2|Bacteria	N	domain, Protein	-	-	3.2.1.4,3.4.17.14	ko:K01179,ko:K07260,ko:K13735	ko00500,ko00550,ko01100,ko01502,ko02020,ko05100,map00500,map00550,map01100,map01502,map02020,map05100	M00651	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	GH5,GH9	-	Big_1,Big_2,Glug,IAT_beta,Invasin_D3,LysM,Mfa_like_1,SLH
LZS3_k127_7881535_14	1121434.AULY01000007_gene1622	1.632e-81	282.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
LZS3_k127_7881535_16	880073.Calab_0059	1.703e-71	254.0	COG0673@1|root,COG0673@2|Bacteria,2NQ2X@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	ycjS	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
LZS3_k127_7881535_17	269799.Gmet_2367	7.755e-69	265.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
LZS3_k127_7881535_30	497964.CfE428DRAFT_1579	4.305e-31	128.0	COG0853@1|root,COG0853@2|Bacteria,46W3T@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
LZS3_k127_7881535_21	1499967.BAYZ01000103_gene3745	3.159e-58	219.0	COG0013@1|root,COG0013@2|Bacteria,2NPQB@2323|unclassified Bacteria	2|Bacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
LZS3_k127_7881535_38	1408473.JHXO01000010_gene3694	4.98e-06	59.0	2ET0X@1|root,33KJ5@2|Bacteria,4NZM8@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7881535_25	1379698.RBG1_1C00001G0634	7.518e-45	169.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
LZS3_k127_7881535_23	1297742.A176_02723	4.526e-52	210.0	COG0652@1|root,COG1413@1|root,COG0652@2|Bacteria,COG1413@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
LZS3_k127_7881535_36	1501230.ET33_28955	1.771e-06	59.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli,26UWQ@186822|Paenibacillaceae	91061|Bacilli	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
LZS3_k127_7881535_22	1120973.AQXL01000112_gene1102	2.106e-56	212.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,279KN@186823|Alicyclobacillaceae	91061|Bacilli	J	tRNA pseudouridine synthase	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
LZS3_k127_7881535_11	647113.Metok_0228	1.116e-84	287.0	COG0176@1|root,arCOG05061@2157|Archaea,2XTET@28890|Euryarchaeota,23Q23@183939|Methanococci	183939|Methanococci	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
LZS3_k127_7881535_15	379066.GAU_1730	3.894e-74	267.0	COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_7881535_7	264732.Moth_2052	3.254e-169	541.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,42FJ7@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
LZS3_k127_7881535_3	382464.ABSI01000002_gene4377	4.976e-191	612.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
LZS3_k127_7881535_28	991905.SL003B_1803	2.447e-35	139.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2U9MH@28211|Alphaproteobacteria,4BS8Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS3_k127_7881535_33	383372.Rcas_2505	1.77e-27	130.0	COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7881535_37	1089544.KB912942_gene4812	4.843e-06	59.0	COG1807@1|root,COG1807@2|Bacteria,2IEB9@201174|Actinobacteria,4E27D@85010|Pseudonocardiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7881535_9	1121957.ATVL01000014_gene1459	1.129e-119	415.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7881535_6	1408445.JHXP01000009_gene2839	9.666e-170	563.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1JDPB@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
LZS3_k127_7881535_24	1094715.CM001373_gene3315	7.956e-52	194.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,1SVID@1236|Gammaproteobacteria,1JD85@118969|Legionellales	118969|Legionellales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
LZS3_k127_7881535_1	243090.RB3877	1.266e-296	914.0	COG3119@1|root,COG3119@2|Bacteria,2IXNZ@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
LZS3_k127_7881535_5	1379698.RBG1_1C00001G1211	9.101e-176	566.0	COG0034@1|root,COG0034@2|Bacteria,2NNSY@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iSB619.SA_RS05225	GATase_6,GATase_7,Pribosyltran
LZS3_k127_7881535_34	1379698.RBG1_1C00001G0940	6.087e-21	102.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,2NNKI@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
LZS3_k127_7881535_8	379066.GAU_1700	1.074e-136	452.0	COG1530@1|root,COG1530@2|Bacteria,1ZSZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
LZS3_k127_7881535_4	216596.RL3058	7.183e-188	597.0	COG5361@1|root,COG5361@2|Bacteria,1MWTW@1224|Proteobacteria,2TUR1@28211|Alphaproteobacteria,4B93D@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
LZS3_k127_7881535_19	395493.BegalDRAFT_2496	5.826e-64	227.0	COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,1S6KW@1236|Gammaproteobacteria,462QH@72273|Thiotrichales	72273|Thiotrichales	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
LZS3_k127_7881535_13	1124780.ANNU01000078_gene768	3.891e-84	284.0	COG4221@1|root,COG4221@2|Bacteria,4NFSY@976|Bacteroidetes,47PUC@768503|Cytophagia	976|Bacteroidetes	S	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
LZS3_k127_7881535_39	547559.Nmag_4162	5.706e-05	49.0	arCOG11653@1|root,arCOG11653@2157|Archaea,2XZD2@28890|Euryarchaeota,23X2N@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7881535_27	290397.Adeh_4128	1.164e-35	152.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS3_k127_7881535_0	945713.IALB_3112	0.0	1435.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
LZS3_k127_7881535_20	349521.HCH_04255	8.235e-61	218.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,1S4X5@1236|Gammaproteobacteria,1XPB8@135619|Oceanospirillales	135619|Oceanospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
LZS3_k127_7881535_31	1124780.ANNU01000005_gene2456	4.443e-29	119.0	COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,47R7R@768503|Cytophagia	976|Bacteroidetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Rho_N,Ribosomal_L21p
LZS3_k127_7881535_29	82654.Pse7367_0506	3.704e-34	134.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HCCX@1150|Oscillatoriales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
LZS3_k127_7881535_18	338963.Pcar_1946	3.555e-65	234.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43TY0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
LZS3_k127_7881535_2	941824.TCEL_00148	2.398e-223	704.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,36DBK@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
LZS3_k127_7881535_10	1125863.JAFN01000001_gene909	5.231e-86	291.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
LZS3_k127_7911130_0	1232410.KI421416_gene2699	1.755e-205	653.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2WJJP@28221|Deltaproteobacteria,43UUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sulfate permease family	ychM	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Pro_CA,STAS,STAS_2,Sulfate_transp
LZS3_k127_7911130_14	313596.RB2501_05040	4.511e-43	162.0	COG0346@1|root,COG0346@2|Bacteria,4NNNG@976|Bacteroidetes,1I1XF@117743|Flavobacteriia	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
LZS3_k127_7911130_18	1121440.AUMA01000007_gene1334	8.845e-33	137.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42SPW@68525|delta/epsilon subdivisions,2WP7F@28221|Deltaproteobacteria,2M954@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
LZS3_k127_7911130_2	123214.PERMA_0871	4.971e-114	381.0	COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae	200783|Aquificae	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
LZS3_k127_7911130_26	1038860.AXAP01000062_gene2409	9.719e-15	87.0	2FA6B@1|root,342F2@2|Bacteria,1NY19@1224|Proteobacteria,2UTGJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7911130_27	163908.KB235895_gene5035	1.004e-09	71.0	2C4F2@1|root,331RG@2|Bacteria,1G9S1@1117|Cyanobacteria,1HNEK@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7911130_19	102129.Lepto7375DRAFT_7165	6.59e-31	125.0	2C7RX@1|root,32RJP@2|Bacteria,1G859@1117|Cyanobacteria,1HC7Z@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7911130_3	477974.Daud_0439	8.567e-108	359.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,24GY3@186801|Clostridia,262MF@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
LZS3_k127_7911130_25	1380393.JHVP01000007_gene4261	1.629e-18	99.0	COG0438@1|root,COG0438@2|Bacteria,2IPZ7@201174|Actinobacteria,4EW0S@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
LZS3_k127_7911130_16	1129374.AJE_12598	2.299e-40	154.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,1RQUD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MgtC SapB transporter	mgtC	GO:0008150,GO:0009405,GO:0044419,GO:0051704	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
LZS3_k127_7911130_7	1121943.KB899989_gene3184	2.616e-67	239.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,1T62V@1236|Gammaproteobacteria,1XJK3@135619|Oceanospirillales	135619|Oceanospirillales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
LZS3_k127_7911130_22	452637.Oter_0944	8.795e-27	112.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,3K87F@414999|Opitutae	414999|Opitutae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
LZS3_k127_7911130_1	477974.Daud_0168	1.772e-135	452.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,261BW@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
LZS3_k127_7911130_10	1397528.Q671_11925	1.448e-55	201.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,1RPN1@1236|Gammaproteobacteria,1XHWE@135619|Oceanospirillales	135619|Oceanospirillales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
LZS3_k127_7911130_5	1121423.JONT01000011_gene253	2.118e-76	265.0	COG0382@1|root,COG0382@2|Bacteria,1TQU5@1239|Firmicutes,2486B@186801|Clostridia,25ZZE@186807|Peptococcaceae	186801|Clostridia	H	PFAM UbiA prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
LZS3_k127_7911130_24	706587.Desti_1875	1.933e-21	104.0	COG0640@1|root,COG0640@2|Bacteria,1R0XC@1224|Proteobacteria	1224|Proteobacteria	K	STAS-like domain of unknown function (DUF4325)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4325
LZS3_k127_7911130_21	661478.OP10G_0647	2.43e-27	121.0	COG1378@1|root,COG1378@2|Bacteria	2|Bacteria	K	Sugar-specific transcriptional regulator TrmB	yrhO	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	Regulator_TrmB,TrmB
LZS3_k127_7911130_11	316067.Geob_0673	2.274e-54	208.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42UDS@68525|delta/epsilon subdivisions,2WPGE@28221|Deltaproteobacteria,43SVS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
LZS3_k127_7911130_6	1433126.BN938_1139	5.867e-70	245.0	COG3340@1|root,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,2FQTC@200643|Bacteroidia,22U8N@171550|Rikenellaceae	976|Bacteroidetes	E	Belongs to the peptidase S51 family	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
LZS3_k127_7911130_17	335543.Sfum_4020	1.262e-34	141.0	COG5523@1|root,COG5523@2|Bacteria,1QZ4S@1224|Proteobacteria	1224|Proteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_7911130_15	1382358.JHVN01000006_gene165	8.84e-41	158.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1TQX3@1239|Firmicutes,4HCI6@91061|Bacilli,21V7U@150247|Anoxybacillus	91061|Bacilli	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
LZS3_k127_7911130_9	237368.SCABRO_01139	8.548e-61	222.0	COG0618@1|root,COG0618@2|Bacteria,2IYQ0@203682|Planctomycetes	203682|Planctomycetes	S	phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
LZS3_k127_7911130_13	1500890.JQNL01000001_gene648	4.308e-49	177.0	COG0599@1|root,COG0599@2|Bacteria,1N38Z@1224|Proteobacteria,1S5G6@1236|Gammaproteobacteria,1X6C8@135614|Xanthomonadales	135614|Xanthomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
LZS3_k127_7911130_8	338963.Pcar_0602	7.452e-62	220.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,42S19@68525|delta/epsilon subdivisions,2WNGU@28221|Deltaproteobacteria,43U16@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Endonuclease V	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
LZS3_k127_7911130_23	886293.Sinac_6080	7.425e-24	112.0	COG1427@1|root,COG1427@2|Bacteria,2IYUW@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
LZS3_k127_7911130_30	404380.Gbem_1112	0.0001718	54.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
LZS3_k127_7911130_4	861299.J421_3506	9.959e-101	343.0	COG2262@1|root,COG2262@2|Bacteria,1ZSYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
LZS3_k127_7911130_29	1379698.RBG1_1C00001G0991	5.931e-08	65.0	COG2911@1|root,COG2931@1|root,COG4447@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4447@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_3,DUF1735,Laminin_G_3
LZS3_k127_7911130_28	1379270.AUXF01000006_gene79	2.566e-09	59.0	COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
LZS3_k127_8067747_10	1408164.MOLA814_00866	2.482e-113	379.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
LZS3_k127_8067747_37	459349.CLOAM0631	2.104e-20	107.0	COG1361@1|root,COG4412@1|root,COG1361@2|Bacteria,COG4412@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,Peptidase_C25,Peptidase_C25_C,Propeptide_C25,W_rich_C,fn3
LZS3_k127_8067747_38	631362.Thi970DRAFT_00652	4.747e-18	91.0	COG3152@1|root,COG3152@2|Bacteria	2|Bacteria	L	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352,DUF805
LZS3_k127_8067747_18	880073.Calab_3350	7.013e-81	284.0	COG0644@1|root,COG0644@2|Bacteria,2NQ4F@2323|unclassified Bacteria	2|Bacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
LZS3_k127_8067747_46	1121930.AQXG01000001_gene1165	9.459e-08	65.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Laminin_G_3
LZS3_k127_8067747_7	313606.M23134_05227	8.023e-140	469.0	COG1404@1|root,COG4733@1|root,COG1404@2|Bacteria,COG4733@2|Bacteria,4PM4C@976|Bacteroidetes,47KZM@768503|Cytophagia	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,fn3
LZS3_k127_8067747_19	861299.J421_2922	1.233e-76	268.0	COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_8067747_27	751994.AGIG01000028_gene2025	2.637e-55	205.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria	1224|Proteobacteria	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
LZS3_k127_8067747_30	1337936.IJ00_02870	1.075e-41	159.0	COG2335@1|root,COG2335@2|Bacteria,1G5TY@1117|Cyanobacteria,1HNEC@1161|Nostocales	1117|Cyanobacteria	M	COGs COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
LZS3_k127_8067747_28	234267.Acid_5474	1.252e-47	177.0	COG4276@1|root,COG4276@2|Bacteria,3Y57N@57723|Acidobacteria	57723|Acidobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
LZS3_k127_8067747_35	56780.SYN_00173	1.016e-23	106.0	COG0784@1|root,COG0784@2|Bacteria,1QUK7@1224|Proteobacteria,431U0@68525|delta/epsilon subdivisions,2WW6W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
LZS3_k127_8067747_16	926550.CLDAP_40500	9.68e-84	287.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	2|Bacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
LZS3_k127_8067747_6	469383.Cwoe_2964	8.463e-144	480.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4CRNQ@84995|Rubrobacteria	84995|Rubrobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
LZS3_k127_8067747_11	439235.Dalk_2046	4.598e-109	372.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MIEE@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
LZS3_k127_8067747_5	926550.CLDAP_34670	3.561e-154	499.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
LZS3_k127_8067747_3	926550.CLDAP_34630	1.177e-164	532.0	COG0168@1|root,COG0168@2|Bacteria,2G84B@200795|Chloroflexi	200795|Chloroflexi	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS3_k127_8067747_4	926550.CLDAP_34630	8.716e-163	526.0	COG0168@1|root,COG0168@2|Bacteria,2G84B@200795|Chloroflexi	200795|Chloroflexi	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
LZS3_k127_8067747_24	1120965.AUBV01000009_gene3096	4.728e-64	235.0	COG2755@1|root,COG2755@2|Bacteria,4P0MH@976|Bacteroidetes	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
LZS3_k127_8067747_36	1168289.AJKI01000002_gene2502	7.641e-22	102.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,2FUPU@200643|Bacteroidia,3XK7D@558415|Marinilabiliaceae	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
LZS3_k127_8067747_31	338963.Pcar_2324	8.619e-37	149.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,43SFK@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
LZS3_k127_8067747_22	1160707.AJIK01000021_gene1837	2.226e-68	242.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli,26DCH@186818|Planococcaceae	91061|Bacilli	K	Belongs to the ParB family	spo0J	GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,KorB,ParBc
LZS3_k127_8067747_14	1121918.ARWE01000001_gene3520	1.368e-96	321.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,43T9A@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
LZS3_k127_8067747_48	215803.DB30_4240	0.0001423	54.0	COG3055@1|root,COG3055@2|Bacteria,1QX72@1224|Proteobacteria,43BZV@68525|delta/epsilon subdivisions,2X7AM@28221|Deltaproteobacteria,2YX4N@29|Myxococcales	28221|Deltaproteobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8067747_41	1217720.ALOX01000117_gene2851	2.221e-12	76.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,2JS6N@204441|Rhodospirillales	204441|Rhodospirillales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
LZS3_k127_8067747_2	330214.NIDE0362	1.332e-216	689.0	COG0445@1|root,COG0445@2|Bacteria,3J0E9@40117|Nitrospirae	40117|Nitrospirae	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
LZS3_k127_8067747_13	404380.Gbem_4058	1.038e-99	341.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,42M6T@68525|delta/epsilon subdivisions,2WIWY@28221|Deltaproteobacteria,43TPQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
LZS3_k127_8067747_9	1121104.AQXH01000002_gene548	1.871e-127	435.0	COG1629@1|root,COG4771@2|Bacteria,4NF4B@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
LZS3_k127_8067747_32	1121423.JONT01000003_gene1131	1.39e-34	141.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,260UK@186807|Peptococcaceae	186801|Clostridia	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
LZS3_k127_8067747_20	96561.Dole_0102	1.1e-69	260.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2MJ96@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
LZS3_k127_8067747_34	211114.JOEF01000003_gene2837	8.172e-25	109.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,4E5Q0@85010|Pseudonocardiales	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
LZS3_k127_8067747_43	760142.Hipma_0092	1.473e-09	67.0	COG0594@1|root,COG0594@2|Bacteria,1NIPY@1224|Proteobacteria,4344S@68525|delta/epsilon subdivisions,2X581@28221|Deltaproteobacteria,2M7GC@213113|Desulfurellales	28221|Deltaproteobacteria	J	Ribonuclease P	-	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
LZS3_k127_8067747_39	1122164.JHWF01000003_gene2152	7.071e-15	76.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1JF92@118969|Legionellales	118969|Legionellales	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
LZS3_k127_8067747_8	1160707.AJIK01000044_gene1703	1.415e-139	457.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,26E4R@186818|Planococcaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
LZS3_k127_8067747_15	521011.Mpal_0423	3.334e-84	289.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
LZS3_k127_8067747_17	1379270.AUXF01000002_gene1191	1.294e-83	291.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
LZS3_k127_8067747_26	1123226.KB899284_gene3651	6.42e-56	210.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,26QB9@186822|Paenibacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
LZS3_k127_8067747_12	1123242.JH636434_gene5497	6.923e-106	374.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
LZS3_k127_8067747_42	867903.ThesuDRAFT_00465	4.664e-12	72.0	COG5512@1|root,COG5512@2|Bacteria,1V9FF@1239|Firmicutes,24XCD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
LZS3_k127_8067747_1	986075.CathTA2_0905	4.608e-274	857.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
LZS3_k127_8067747_29	595460.RRSWK_07231	2.357e-44	166.0	COG4914@1|root,COG4914@2|Bacteria,2J4D4@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8067747_21	204669.Acid345_1475	1.173e-69	254.0	COG0436@1|root,COG0436@2|Bacteria,3Y5AV@57723|Acidobacteria,2JJXH@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
LZS3_k127_8067747_25	448385.sce3387	5.081e-61	235.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8067747_33	383372.Rcas_2311	2.173e-27	118.0	COG1246@1|root,COG1246@2|Bacteria,2G9DB@200795|Chloroflexi,377S6@32061|Chloroflexia	32061|Chloroflexia	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
LZS3_k127_8067747_23	448385.sce3387	3.188e-64	241.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8067747_40	446466.Cfla_2839	3.315e-13	72.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
LZS3_k127_8067747_0	1379698.RBG1_1C00001G0278	6.808e-313	976.0	COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
LZS3_k127_8175067_1	713587.THITH_08540	1.051e-144	467.0	COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,1S93R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
LZS3_k127_8175067_14	313606.M23134_02768	1.845e-31	133.0	COG0457@1|root,COG0457@2|Bacteria,4PBAK@976|Bacteroidetes,47VJ2@768503|Cytophagia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8175067_5	331869.BAL199_02619	7.293e-89	308.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,4BPEK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
LZS3_k127_8175067_3	1379698.RBG1_1C00001G1345	9.145e-106	365.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c_2,SSF,SpoIIE
LZS3_k127_8175067_13	159087.Daro_0155	7.544e-42	169.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,2KWP5@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
LZS3_k127_8175067_2	1167006.UWK_01424	2.536e-141	461.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2MI9P@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
LZS3_k127_8175067_16	1121396.KB893095_gene4378	3.019e-20	98.0	COG3090@1|root,COG3090@2|Bacteria,1MZNX@1224|Proteobacteria,42TZJ@68525|delta/epsilon subdivisions,2WQB8@28221|Deltaproteobacteria,2MKJH@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Tripartite ATP-independent periplasmic transporter, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
LZS3_k127_8175067_7	880073.Calab_1130	1.042e-82	287.0	COG1638@1|root,COG1638@2|Bacteria,2NS33@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
LZS3_k127_8175067_15	1163617.SCD_n01357	7.381e-30	132.0	COG5660@1|root,32WII@2|Bacteria,1R3ME@1224|Proteobacteria	1224|Proteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
LZS3_k127_8175067_12	1449126.JQKL01000003_gene1717	1.078e-49	181.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,26973@186813|unclassified Clostridiales	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
LZS3_k127_8175067_10	1379698.RBG1_1C00001G0723	6.894e-61	230.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
LZS3_k127_8175067_17	1232410.KI421428_gene1047	1.817e-17	90.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria,43V6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
LZS3_k127_8175067_6	861299.J421_3197	1.913e-84	293.0	COG0796@1|root,COG0796@2|Bacteria,1ZUQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
LZS3_k127_8175067_8	322710.Avin_02850	1.058e-81	283.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
LZS3_k127_8175067_11	330214.NIDE1872	3.458e-54	198.0	COG0127@1|root,COG0127@2|Bacteria,3J0ST@40117|Nitrospirae	40117|Nitrospirae	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
LZS3_k127_8175067_4	1047013.AQSP01000052_gene2600	1.218e-99	335.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
LZS3_k127_8175067_9	1047013.AQSP01000052_gene2599	2.466e-73	268.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
LZS3_k127_8175067_0	377629.TERTU_3942	3.923e-145	485.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,2PPKQ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	OPT oligopeptide transporter protein	oliA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	OPT
LZS3_k127_8175067_21	1184267.A11Q_1219	0.0001117	54.0	2AIQT@1|root,3197J@2|Bacteria,1Q1ZE@1224|Proteobacteria,437MA@68525|delta/epsilon subdivisions,2MU3U@213481|Bdellovibrionales,2WYMC@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8176493_26	1003195.SCAT_4917	0.0001198	51.0	COG1309@1|root,COG1309@2|Bacteria,2GMVQ@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
LZS3_k127_8176493_17	632518.Calow_0891	3.162e-25	115.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,42G25@68295|Thermoanaerobacterales	186801|Clostridia	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
LZS3_k127_8176493_15	1123392.AQWL01000004_gene2645	7.583e-33	143.0	COG5002@1|root,COG5002@2|Bacteria,1QTV1@1224|Proteobacteria,2WGQF@28216|Betaproteobacteria,1KRCK@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA
LZS3_k127_8176493_12	1485545.JQLW01000006_gene531	6.919e-68	241.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria	1224|Proteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_8176493_23	1123405.AUMM01000023_gene1955	5.798e-14	82.0	COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,4I42H@91061|Bacilli,26PW5@186821|Sporolactobacillaceae	91061|Bacilli	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_8176493_24	472759.Nhal_1592	1.688e-12	75.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria,1WZ9P@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
LZS3_k127_8176493_18	767817.Desgi_1439	1.78e-23	109.0	COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,24HXX@186801|Clostridia,262JG@186807|Peptococcaceae	186801|Clostridia	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
LZS3_k127_8176493_13	700598.Niako_7284	2.231e-35	145.0	COG4977@1|root,COG4977@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
LZS3_k127_8176493_6	1267533.KB906735_gene5050	3.629e-112	374.0	COG3503@1|root,COG3503@2|Bacteria,3Y3XK@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
LZS3_k127_8176493_10	1317122.ATO12_18600	3.055e-77	267.0	COG0500@1|root,COG2226@2|Bacteria,4PHDE@976|Bacteroidetes,1IMF4@117743|Flavobacteriia,2YKMN@290174|Aquimarina	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
LZS3_k127_8176493_8	1185876.BN8_00183	3.288e-111	388.0	COG0308@1|root,COG0308@2|Bacteria,4NG5Q@976|Bacteroidetes,47JW1@768503|Cytophagia	976|Bacteroidetes	E	Peptidase M1, membrane alanine aminopeptidase	pepN1	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
LZS3_k127_8176493_2	502025.Hoch_4014	1.655e-175	573.0	COG0451@1|root,COG0673@1|root,COG0451@2|Bacteria,COG0673@2|Bacteria,1PEGY@1224|Proteobacteria,4345A@68525|delta/epsilon subdivisions,2X3ZH@28221|Deltaproteobacteria,2YXPP@29|Myxococcales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_8176493_4	357808.RoseRS_0130	1.175e-155	503.0	COG0451@1|root,COG0451@2|Bacteria,2G5PB@200795|Chloroflexi,37576@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
LZS3_k127_8176493_7	926566.Terro_1379	9.462e-112	370.0	COG0451@1|root,COG0451@2|Bacteria,3Y3DJ@57723|Acidobacteria,2JIZM@204432|Acidobacteriia	204432|Acidobacteriia	M	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
LZS3_k127_8176493_22	1121918.ARWE01000001_gene3225	1.258e-16	84.0	2EIAN@1|root,33C22@2|Bacteria,1NH5M@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8176493_11	1121405.dsmv_1616	1.083e-76	265.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,437EH@68525|delta/epsilon subdivisions,2XA2G@28221|Deltaproteobacteria,2MNAI@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8176493_19	1232410.KI421415_gene2960	3.049e-22	105.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions,2WP03@28221|Deltaproteobacteria,43SHH@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
LZS3_k127_8176493_0	497965.Cyan7822_0632	1.571e-267	843.0	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,3KGAF@43988|Cyanothece	1117|Cyanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
LZS3_k127_8176493_5	765420.OSCT_2611	3.963e-119	409.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi,376G0@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
LZS3_k127_8176493_3	518766.Rmar_2595	3.122e-159	512.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes	976|Bacteroidetes	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
LZS3_k127_8176493_20	298653.Franean1_3402	1.28e-21	96.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria	201174|Actinobacteria	O	Hydrogenase expression formation protein	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
LZS3_k127_8176493_9	857087.Metme_1764	7.586e-82	279.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,1XEEW@135618|Methylococcales	135618|Methylococcales	KO	Hydrogenase accessory protein HypB	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
LZS3_k127_8176493_21	1114959.SZMC14600_07097	4.476e-17	92.0	COG0375@1|root,COG0375@2|Bacteria,2IMJK@201174|Actinobacteria,4E651@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn finger protein HypA HybF (Possibly regulating hydrogenase expression)	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
LZS3_k127_8176493_14	330214.NIDE1575	3.375e-34	141.0	COG2215@1|root,COG2215@2|Bacteria	2|Bacteria	O	Belongs to the NiCoT transporter (TC 2.A.52) family	ureH	-	-	-	-	-	-	-	-	-	-	-	DsbD_2,NicO
LZS3_k127_8176493_1	1499967.BAYZ01000159_gene546	3.44e-214	702.0	2EYYT@1|root,33S5J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8176493_25	1223410.KN050846_gene441	3.135e-06	57.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,1I34P@117743|Flavobacteriia	976|Bacteroidetes	M	Opacity protein	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
LZS3_k127_8249564_9	1125863.JAFN01000001_gene2858	2.693e-97	344.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,42RAY@68525|delta/epsilon subdivisions,2WMP5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
LZS3_k127_8249564_13	1125863.JAFN01000001_gene2857	8.964e-51	198.0	COG3391@1|root,COG3391@2|Bacteria,1RJQF@1224|Proteobacteria,42VW9@68525|delta/epsilon subdivisions,2WRUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8249564_21	880073.Calab_3215	1.112e-21	109.0	COG0366@1|root,COG0708@1|root,COG0366@2|Bacteria,COG0708@2|Bacteria,2NREA@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 70	-	-	3.1.11.2,3.2.1.1	ko:K01142,ko:K01176	ko00500,ko01100,ko03410,ko04973,map00500,map01100,map03410,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000,ko03400	-	GH13	-	Alpha-amylase,CBM_25,DUF1939,He_PIG
LZS3_k127_8249564_22	880073.Calab_0921	4.256e-20	108.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,FctA,Peptidase_M43
LZS3_k127_8249564_26	404589.Anae109_3198	2.229e-15	86.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
LZS3_k127_8249564_18	1123267.JONN01000001_gene1239	1.508e-29	137.0	2C1YS@1|root,2ZD2Y@2|Bacteria	2|Bacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
LZS3_k127_8249564_0	1123267.JONN01000001_gene1238	1.057e-226	741.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,MRJP
LZS3_k127_8249564_19	1200792.AKYF01000009_gene3182	2.413e-29	124.0	COG1595@1|root,COG1595@2|Bacteria,1U40C@1239|Firmicutes,4HCU0@91061|Bacilli,26S2C@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW11	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
LZS3_k127_8249564_28	877415.JNJQ01000042_gene2677	7.689e-10	67.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes	1239|Firmicutes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
LZS3_k127_8249564_24	335543.Sfum_4032	3.167e-18	90.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,42V4M@68525|delta/epsilon subdivisions,2WRKJ@28221|Deltaproteobacteria,2MS4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	anti-sigma regulatory factor	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
LZS3_k127_8249564_14	1163617.SCD_n02328	3.488e-50	181.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2VSE7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	chain release factor	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
LZS3_k127_8249564_23	880073.Calab_2081	1.228e-19	105.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_8249564_27	324602.Caur_2635	5.229e-11	77.0	COG1404@1|root,COG1404@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Peptidase_S8
LZS3_k127_8249564_5	1499967.BAYZ01000155_gene629	3.083e-139	452.0	COG0116@1|root,COG0116@2|Bacteria	2|Bacteria	L	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	rlmL	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
LZS3_k127_8249564_16	926550.CLDAP_26800	4.618e-39	151.0	2E65M@1|root,330UB@2|Bacteria,2G8DC@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
LZS3_k127_8249564_25	880073.Calab_2084	1.311e-17	100.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,FlgD_ig,Peptidase_S74
LZS3_k127_8249564_17	1123503.KB908057_gene2468	1.047e-31	132.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
LZS3_k127_8249564_30	207559.Dde_3362	1.252e-08	59.0	COG2963@1|root,COG2963@2|Bacteria,1N8W3@1224|Proteobacteria,42VV3@68525|delta/epsilon subdivisions,2WSHS@28221|Deltaproteobacteria,2MBW4@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
LZS3_k127_8249564_20	1449357.JQLK01000005_gene2452	2.707e-22	110.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
LZS3_k127_8249564_3	886293.Sinac_4665	9.683e-174	553.0	COG0006@1|root,COG0006@2|Bacteria,2IXJI@203682|Planctomycetes	203682|Planctomycetes	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
LZS3_k127_8249564_15	35754.JNYJ01000089_gene6368	3.595e-46	176.0	COG0730@1|root,COG0730@2|Bacteria,2I5VT@201174|Actinobacteria,4DCRV@85008|Micromonosporales	201174|Actinobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS3_k127_8249564_29	204669.Acid345_4648	4.452e-09	70.0	COG0745@1|root,COG0745@2|Bacteria,3Y8XM@57723|Acidobacteria	57723|Acidobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
LZS3_k127_8249564_7	316067.Geob_0439	4.156e-122	403.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,43TTT@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-3	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
LZS3_k127_8249564_10	309801.trd_A0315	1.835e-89	314.0	COG0265@1|root,COG0265@2|Bacteria,2GBRP@200795|Chloroflexi,27Z1U@189775|Thermomicrobia	189775|Thermomicrobia	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
LZS3_k127_8249564_12	530564.Psta_2595	4.091e-57	207.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
LZS3_k127_8249564_8	357804.Ping_0836	3.435e-109	375.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,2QHI3@267894|Psychromonadaceae	1236|Gammaproteobacteria	T	histidine kinase A domain protein domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS_4,PAS_8
LZS3_k127_8249564_11	706587.Desti_5065	3.667e-75	260.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
LZS3_k127_8249564_6	314230.DSM3645_15600	1.368e-127	428.0	COG1117@1|root,COG1117@2|Bacteria,2IWRV@203682|Planctomycetes	203682|Planctomycetes	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
LZS3_k127_8249564_2	118005.AWNK01000011_gene145	9.04e-201	650.0	COG0581@1|root,COG0581@2|Bacteria	2|Bacteria	P	inorganic phosphate transmembrane transporter activity	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS3_k127_8249564_1	118005.AWNK01000011_gene146	1.536e-201	656.0	COG4590@1|root,COG4590@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
LZS3_k127_8249564_4	118005.AWNK01000011_gene148	1.396e-142	460.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
LZS3_k127_8249564_32	634497.HAH_1278	1.543e-05	57.0	COG4677@1|root,arCOG02495@2157|Archaea	2157|Archaea	G	COG4677 Pectin methylesterase	pecE	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta_helix,NosD,PKD,Pectinesterase
LZS3_k127_8249564_31	1379698.RBG1_1C00001G1831	1.449e-08	67.0	COG2706@1|root,COG4733@1|root,COG2706@2|Bacteria,COG4733@2|Bacteria,2NR81@2323|unclassified Bacteria	2|Bacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	PKD,VCBS
LZS3_k127_8305402_14	1408422.JHYF01000029_gene3541	5.469e-09	64.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,36FTT@31979|Clostridiaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
LZS3_k127_8305402_4	1177179.A11A3_15217	4.774e-120	400.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,1RPGZ@1236|Gammaproteobacteria,1XQZJ@135619|Oceanospirillales	135619|Oceanospirillales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
LZS3_k127_8305402_9	266762.HQ36_05260	9.215e-38	148.0	COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia,22Y67@171551|Porphyromonadaceae	976|Bacteroidetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
LZS3_k127_8305402_5	485913.Krac_8783	3.116e-110	368.0	COG0404@1|root,COG0404@2|Bacteria,2G5VA@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
LZS3_k127_8305402_0	429009.Adeg_1824	0.0	1141.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
LZS3_k127_8305402_12	1453500.AT05_08815	2.274e-14	81.0	2DQEZ@1|root,336F0@2|Bacteria,4NUK8@976|Bacteroidetes,1I4H2@117743|Flavobacteriia	976|Bacteroidetes	S	Reeler domain	-	-	-	-	-	-	-	-	-	-	-	-	Reeler
LZS3_k127_8305402_8	1122604.JONR01000020_gene457	3.678e-47	179.0	COG1247@1|root,COG1247@2|Bacteria,1RGU8@1224|Proteobacteria,1S791@1236|Gammaproteobacteria,1X65R@135614|Xanthomonadales	135614|Xanthomonadales	M	COG1247 Sortase and related acyltransferases	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
LZS3_k127_8305402_2	204669.Acid345_2395	1.634e-162	536.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
LZS3_k127_8305402_11	643867.Ftrac_2337	1.579e-16	81.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,47S4A@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
LZS3_k127_8305402_3	1122939.ATUD01000010_gene2912	1.596e-153	500.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CPZQ@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
LZS3_k127_8305402_6	748247.AZKH_2773	6.305e-103	343.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2VK8F@28216|Betaproteobacteria,2KWZJ@206389|Rhodocyclales	206389|Rhodocyclales	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
LZS3_k127_8305402_13	518766.Rmar_1071	3.002e-11	77.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
LZS3_k127_8305402_7	247490.KSU1_C0449	1.267e-62	243.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_8305402_1	1144275.COCOR_07662	0.0	1090.0	COG0308@1|root,COG1668@1|root,COG0308@2|Bacteria,COG1668@2|Bacteria,1PTWJ@1224|Proteobacteria	1224|Proteobacteria	E	Peptidase family M1 domain	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4,Peptidase_M1
LZS3_k127_8305402_10	1144275.COCOR_07663	9.772e-22	97.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria	1224|Proteobacteria	V	(ABC) transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
LZS3_k127_8579319_5	1192034.CAP_3957	3.198e-44	180.0	COG1520@1|root,COG4935@1|root,COG1520@2|Bacteria,COG4935@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2X2U1@28221|Deltaproteobacteria,2YWRC@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8579319_12	448385.sce8929	9.755e-19	93.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_8579319_2	240015.ACP_0184	1.546e-89	327.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y3HX@57723|Acidobacteria,2JHJ9@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_8
LZS3_k127_8579319_17	1353529.M899_2597	1.726e-07	63.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	3.4.21.7	ko:K01315	ko04080,ko04610,ko05150,ko05164,map04080,map04610,map05150,map05164	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147,ko04516	-	-	-	PPC,Trypsin_2
LZS3_k127_8579319_7	314230.DSM3645_18456	1.364e-37	149.0	COG1595@1|root,COG1595@2|Bacteria,2J2RR@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
LZS3_k127_8579319_4	580331.Thit_1306	2.54e-52	199.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
LZS3_k127_8579319_20	1443665.JACA01000036_gene2231	0.0008612	50.0	2E9MR@1|root,333UC@2|Bacteria,4NVJT@976|Bacteroidetes,1I63J@117743|Flavobacteriia,2YIFN@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8579319_14	459349.CLOAM0582	9.45e-14	85.0	COG1572@1|root,COG3391@1|root,COG4412@1|root,COG4733@1|root,COG1572@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,COG4733@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	3.4.21.96	ko:K01361,ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	F5_F8_type_C,Glucosaminidase,SLH
LZS3_k127_8579319_13	880073.Calab_2081	1.369e-17	98.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_8579319_1	330214.NIDE1904	3.314e-92	310.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
LZS3_k127_8579319_9	555779.Dthio_PD0409	4.053e-25	110.0	COG3514@1|root,COG3514@2|Bacteria,1NA6F@1224|Proteobacteria,42WIF@68525|delta/epsilon subdivisions,2WR86@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
LZS3_k127_8579319_18	1008457.BAEX01000021_gene1873	7.38e-07	61.0	COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,1HY1W@117743|Flavobacteriia,47IRJ@76831|Myroides	976|Bacteroidetes	CO	Domain of unknown function (DUF4369)	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DUF4369,Thioredoxin_8
LZS3_k127_8579319_19	1430331.EP10_15525	2.969e-05	55.0	COG0793@1|root,COG0793@2|Bacteria,1V0GW@1239|Firmicutes,4HA53@91061|Bacilli,1WG7W@129337|Geobacillus	91061|Bacilli	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Big_5,PDZ,PDZ_2,Peptidase_S41
LZS3_k127_8579319_10	314278.NB231_17498	1.86e-24	106.0	COG3514@1|root,COG3514@2|Bacteria,1NA6F@1224|Proteobacteria,1SFKS@1236|Gammaproteobacteria,1X2MG@135613|Chromatiales	135613|Chromatiales	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
LZS3_k127_8579319_8	397945.Aave_0007	7.223e-36	143.0	COG1708@1|root,COG1708@2|Bacteria,1RCAH@1224|Proteobacteria,2VQYD@28216|Betaproteobacteria,4AE74@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM DNA polymerase, beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
LZS3_k127_8579319_6	28072.Nos7524_1819	2.639e-43	183.0	COG1404@1|root,COG1572@1|root,COG2374@1|root,COG2931@1|root,COG3209@1|root,COG3291@1|root,COG4932@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG2374@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,1GIN1@1117|Cyanobacteria,1HNE9@1161|Nostocales	1117|Cyanobacteria	MOQ	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,PPC,Peptidase_S8,SdrD_B
LZS3_k127_8579319_11	880073.Calab_2081	2.067e-21	111.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
LZS3_k127_8579319_15	706587.Desti_5216	1.454e-12	79.0	2E90H@1|root,3339X@2|Bacteria,1NMSR@1224|Proteobacteria,42XCQ@68525|delta/epsilon subdivisions,2WSNY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8579319_0	1121405.dsmv_1797	6.077e-110	367.0	28IPJ@1|root,2Z8PI@2|Bacteria,1N3K3@1224|Proteobacteria,42YFP@68525|delta/epsilon subdivisions,2WTSC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8579319_3	227377.CBU_1788	5.471e-57	205.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
LZS3_k127_8642276_12	246195.DNO_0890	1.138e-05	54.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,1SCBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG4968 Tfp pilus assembly protein PilE	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
LZS3_k127_8642276_13	1196835.A458_16900	0.0003415	49.0	COG4967@1|root,COG4967@2|Bacteria,1NDDQ@1224|Proteobacteria,1SQXH@1236|Gammaproteobacteria,1Z31U@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	NU	Pilus assembly protein PilV	pilV	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
LZS3_k127_8642276_10	1304885.AUEY01000045_gene258	4.076e-13	77.0	COG4966@1|root,COG4966@2|Bacteria,1N2NR@1224|Proteobacteria,42TRJ@68525|delta/epsilon subdivisions,2WQQ2@28221|Deltaproteobacteria,2MKHU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	pilus assembly protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
LZS3_k127_8642276_0	269799.Gmet_0737	1.622e-123	428.0	COG2304@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WKJV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,PA14
LZS3_k127_8642276_11	195250.CM001776_gene1221	9.998e-06	57.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8642276_9	1464048.JNZS01000017_gene3649	5.166e-24	109.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4D8ZN@85008|Micromonosporales	201174|Actinobacteria	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
LZS3_k127_8642276_4	1304888.ATWF01000001_gene2206	2e-50	184.0	COG0669@1|root,COG0669@2|Bacteria,2GFI7@200930|Deferribacteres	200930|Deferribacteres	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
LZS3_k127_8642276_1	760568.Desku_0428	4.414e-98	330.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25ZZB@186807|Peptococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
LZS3_k127_8642276_3	1123368.AUIS01000015_gene2642	6.881e-56	209.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,2NCQK@225057|Acidithiobacillales	225057|Acidithiobacillales	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
LZS3_k127_8642276_5	1379698.RBG1_1C00001G1514	1.738e-47	181.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
LZS3_k127_8642276_8	1519464.HY22_09940	9.566e-30	121.0	COG4191@1|root,COG4191@2|Bacteria,1FFJ1@1090|Chlorobi	1090|Chlorobi	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
LZS3_k127_8642276_2	330214.NIDE2553	1.058e-76	268.0	COG2870@1|root,COG2870@2|Bacteria,3J0GT@40117|Nitrospirae	40117|Nitrospirae	M	Phosphomethylpyrimidine kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
LZS3_k127_8642276_6	78245.Xaut_3773	8.163e-43	165.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TU12@28211|Alphaproteobacteria,3F111@335928|Xanthobacteraceae	28211|Alphaproteobacteria	F	Cytidylyltransferase-like	hldE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
LZS3_k127_8642276_7	880073.Calab_0633	1.99e-37	149.0	COG2403@1|root,COG2403@2|Bacteria,2NNTB@2323|unclassified Bacteria	2|Bacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	cobW
LZS3_k127_8651380_45	1123073.KB899242_gene944	9.703e-06	55.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,1S3Y4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH
LZS3_k127_8651380_43	94624.Bpet2508	9.774e-08	59.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2VRED@28216|Betaproteobacteria,3T446@506|Alcaligenaceae	28216|Betaproteobacteria	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
LZS3_k127_8651380_13	1382303.JPOM01000001_gene1296	5.662e-84	287.0	COG1028@1|root,COG1028@2|Bacteria,1R8HN@1224|Proteobacteria,2U0TG@28211|Alphaproteobacteria,2KIT0@204458|Caulobacterales	204458|Caulobacterales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
LZS3_k127_8651380_39	1382356.JQMP01000004_gene207	9.273e-14	84.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
LZS3_k127_8651380_10	867903.ThesuDRAFT_00760	9.769e-92	314.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,3WCG0@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
LZS3_k127_8651380_23	644966.Tmar_2219	2.924e-42	162.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
LZS3_k127_8651380_22	469381.Dpep_1907	6.234e-43	167.0	COG1490@1|root,COG1490@2|Bacteria,3TB52@508458|Synergistetes	508458|Synergistetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
LZS3_k127_8651380_11	518766.Rmar_2564	1.36e-91	323.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1FJ1M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
LZS3_k127_8651380_42	1037409.BJ6T_28130	1.255e-08	62.0	28Y26@1|root,2ZJXS@2|Bacteria,1PAKD@1224|Proteobacteria,2UYIU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8651380_30	293826.Amet_2989	8.615e-27	119.0	COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia	186801|Clostridia	L	PFAM ribonuclease H	rnhA	-	3.1.26.4	ko:K03469,ko:K06864	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
LZS3_k127_8651380_37	671143.DAMO_2754	5.396e-17	90.0	COG1579@1|root,COG1579@2|Bacteria,2NPW0@2323|unclassified Bacteria	2|Bacteria	S	C4-type zinc ribbon domain	CP_0228	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
LZS3_k127_8651380_6	1242864.D187_008792	3.393e-128	432.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
LZS3_k127_8651380_12	1232410.KI421412_gene98	3.866e-89	316.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,43RZN@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	zinc finger	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
LZS3_k127_8651380_7	518766.Rmar_0730	9.398e-116	408.0	COG1193@1|root,COG1193@2|Bacteria,4NFE6@976|Bacteroidetes,1FIM7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
LZS3_k127_8651380_44	470145.BACCOP_00458	6.492e-07	61.0	COG1286@1|root,COG1286@2|Bacteria,4NVNM@976|Bacteroidetes,2FQDH@200643|Bacteroidia,4APBD@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location CytoplasmicMembrane, score	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
LZS3_k127_8651380_31	868864.Dester_0796	2.486e-26	113.0	COG1610@1|root,COG1610@2|Bacteria,2G4V2@200783|Aquificae	200783|Aquificae	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
LZS3_k127_8651380_35	641143.HMPREF9331_00683	2.591e-19	97.0	COG1385@1|root,COG1385@2|Bacteria,4NE2S@976|Bacteroidetes,1HY0K@117743|Flavobacteriia,1EQHM@1016|Capnocytophaga	976|Bacteroidetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
LZS3_k127_8651380_8	517418.Ctha_1824	6.233e-110	368.0	COG0484@1|root,COG0484@2|Bacteria,1FD9R@1090|Chlorobi	1090|Chlorobi	J	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
LZS3_k127_8651380_4	1279009.ADICEAN_02620	9.285e-230	728.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,47JCZ@768503|Cytophagia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
LZS3_k127_8651380_32	936375.HMPREF1152_0042	1.042e-24	115.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3WCM6@538999|Clostridiales incertae sedis	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
LZS3_k127_8651380_25	1191523.MROS_1457	3.206e-38	156.0	COG1420@1|root,COG1420@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	hrcA	GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA,HrcA_DNA-bdg
LZS3_k127_8651380_19	1519439.JPJG01000058_gene2064	9.841e-63	231.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,2N6V9@216572|Oscillospiraceae	186801|Clostridia	H	HemN C-terminal domain	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
LZS3_k127_8651380_18	1379698.RBG1_1C00001G0425	2.655e-64	225.0	COG0681@1|root,COG0681@2|Bacteria,2NPIA@2323|unclassified Bacteria	2|Bacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
LZS3_k127_8651380_2	555079.Toce_0903	8.95e-256	801.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,42F8U@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
LZS3_k127_8651380_46	331678.Cphamn1_2085	3.479e-05	55.0	28PR3@1|root,303J8@2|Bacteria,1FFJ0@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8651380_36	880073.Calab_3296	3.863e-19	101.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
LZS3_k127_8651380_26	1121865.OMW_00484	4.661e-38	146.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli,4B2M3@81852|Enterococcaceae	91061|Bacilli	J	Endoribonuclease L-PSP	aldR	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
LZS3_k127_8651380_3	1519464.HY22_02080	4.755e-245	770.0	COG0449@1|root,COG0449@2|Bacteria,1FDCR@1090|Chlorobi	1090|Chlorobi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
LZS3_k127_8651380_9	1379698.RBG1_1C00001G0687	3.123e-105	359.0	COG1109@1|root,COG1109@2|Bacteria,2NNM3@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.10,5.4.2.2,5.4.2.8	ko:K01840,ko:K03431,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R02060,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
LZS3_k127_8651380_47	445975.COLSTE_02013	0.0001277	55.0	COG1476@1|root,COG1476@2|Bacteria,2I673@201174|Actinobacteria,4CWV5@84998|Coriobacteriia	84998|Coriobacteriia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
LZS3_k127_8651380_0	880073.Calab_3264	1.214e-262	830.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso,PIG-L
LZS3_k127_8651380_16	1121930.AQXG01000004_gene2868	5.342e-71	276.0	COG1572@1|root,COG2911@1|root,COG4733@1|root,COG1572@2|Bacteria,COG2911@2|Bacteria,COG4733@2|Bacteria,4NYS6@976|Bacteroidetes,1IZ9T@117747|Sphingobacteriia	976|Bacteroidetes	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8651380_29	1121930.AQXG01000004_gene2867	1.752e-28	133.0	COG1404@1|root,COG4254@1|root,COG1404@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FecR
LZS3_k127_8651380_38	459349.CLOAM1520	7.581e-16	92.0	COG4412@1|root,COG4412@2|Bacteria,2NQZW@2323|unclassified Bacteria	2|Bacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cleaved_Adhesin,DUF4968,DUF5110,F5_F8_type_C,FlgD_ig,Glyco_hydro_31,W_rich_C,fn3
LZS3_k127_8651380_33	861299.J421_3303	5.896e-22	105.0	COG0314@1|root,COG0314@2|Bacteria,1ZU08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
LZS3_k127_8651380_40	913325.N799_00555	1.995e-11	68.0	2ANYG@1|root,31DZF@2|Bacteria,1QB9H@1224|Proteobacteria,1T6TX@1236|Gammaproteobacteria,1X857@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_8651380_17	1500893.JQNB01000001_gene127	2.177e-66	250.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1X5HG@135614|Xanthomonadales	135614|Xanthomonadales	H	molybdopterin biosynthesis	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
LZS3_k127_8651380_24	1247963.JPHU01000013_gene632	5.593e-42	175.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
LZS3_k127_8651380_15	1379698.RBG1_1C00001G0911	3.667e-77	268.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,2NPNE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	2.8.1.12,4.6.1.17	ko:K03635,ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395,R11372	RC02507,RC03425	ko00000,ko00001,ko01000	-	-	-	MOSC,MoCF_biosynth,MoaC
LZS3_k127_8651380_14	742818.HMPREF9451_01438	2.489e-82	285.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,4CUGB@84998|Coriobacteriia	84998|Coriobacteriia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
LZS3_k127_8651380_5	1379698.RBG1_1C00001G0513	1.501e-129	426.0	COG0119@1|root,COG0119@2|Bacteria,2NNNZ@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA3	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
LZS3_k127_8651380_27	1380393.JHVP01000005_gene3728	2.143e-32	144.0	COG2080@1|root,COG2080@2|Bacteria,2IN0X@201174|Actinobacteria	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
LZS3_k127_8651380_1	1382306.JNIM01000001_gene1023	3.305e-260	830.0	COG1529@1|root,COG1529@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrA	-	1.3.7.9	ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
LZS3_k127_8651380_20	485913.Krac_2435	5.623e-55	205.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	hcrB	-	1.3.7.9	ko:K04109	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
LZS3_k127_8651380_34	272943.RSP_1934	2.995e-21	106.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria,1FCMX@1060|Rhodobacter	28211|Alphaproteobacteria	O	XdhC and CoxI family	MA20_09415	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
LZS3_k127_8651380_28	666684.AfiDRAFT_0012	1.185e-28	126.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,3JQZ5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Probable molybdopterin binding domain	MA20_09420	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,NTP_transf_3
LZS3_k127_8651380_21	314266.SKA58_01185	5.181e-43	169.0	COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,2V983@28211|Alphaproteobacteria,2K2B5@204457|Sphingomonadales	204457|Sphingomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,GMC_oxred_C,GMC_oxred_N
LZS3_k127_9507_19	521011.Mpal_0423	5.988e-24	102.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
LZS3_k127_9507_13	1254432.SCE1572_29505	3.168e-51	197.0	COG1680@1|root,COG1680@2|Bacteria,1R8N7@1224|Proteobacteria,42WBG@68525|delta/epsilon subdivisions,2WS3Q@28221|Deltaproteobacteria,2YY0X@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
LZS3_k127_9507_8	247490.KSU1_C0449	2.151e-86	315.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_9507_24	880073.Calab_0041	1.189e-13	85.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.14.18.1	ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	BNR,FlgD_ig,Peptidase_S74,Tyrosinase
LZS3_k127_9507_9	1121875.KB907549_gene1918	1.593e-73	255.0	2C3WA@1|root,2Z8P1@2|Bacteria,4NW8R@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_9507_12	1036674.A28LD_0671	2.852e-58	209.0	2DPEU@1|root,331SS@2|Bacteria,1NDKB@1224|Proteobacteria,1RTE7@1236|Gammaproteobacteria,2QG29@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Golgi phosphoprotein 3 (GPP34)	-	-	-	-	-	-	-	-	-	-	-	-	GPP34
LZS3_k127_9507_23	661478.OP10G_3433	1.16e-14	85.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_4,Ank_5
LZS3_k127_9507_21	85643.Tmz1t_3871	2.284e-20	102.0	COG2067@1|root,COG2067@2|Bacteria,1REWT@1224|Proteobacteria,2VVIS@28216|Betaproteobacteria	28216|Betaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
LZS3_k127_9507_0	1283300.ATXB01000001_gene388	0.0	1225.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
LZS3_k127_9507_26	1337936.IJ00_14320	6.997e-10	73.0	COG3420@1|root,COG3420@2|Bacteria,1G2FG@1117|Cyanobacteria,1HJSK@1161|Nostocales	1117|Cyanobacteria	P	TIGRFAM parallel beta-helix repeat (two copies)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1565,SLH
LZS3_k127_9507_7	204773.HEAR1081	6.358e-89	296.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria,474I0@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
LZS3_k127_9507_14	1123508.JH636441_gene3364	2.292e-39	156.0	COG5285@1|root,COG5285@2|Bacteria,2J0Z3@203682|Planctomycetes	203682|Planctomycetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
LZS3_k127_9507_18	103733.JNYO01000039_gene4492	1.916e-25	121.0	2FGPE@1|root,348J0@2|Bacteria,2GPR7@201174|Actinobacteria,4E9W2@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
LZS3_k127_9507_3	1128421.JAGA01000001_gene2438	4.545e-134	435.0	COG1064@1|root,COG1064@2|Bacteria,2NP06@2323|unclassified Bacteria	2|Bacteria	S	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
LZS3_k127_9507_17	1304865.JAGF01000001_gene297	8.967e-26	119.0	COG0288@1|root,COG0288@2|Bacteria,2GT5H@201174|Actinobacteria,4F0KJ@85016|Cellulomonadaceae	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
LZS3_k127_9507_5	522306.CAP2UW1_1272	2.706e-98	341.0	COG4313@1|root,COG4313@2|Bacteria,1PRCN@1224|Proteobacteria,2VQHT@28216|Betaproteobacteria,1KQK1@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
LZS3_k127_9507_25	1205680.CAKO01000042_gene5365	2.254e-13	79.0	2E74W@1|root,331P9@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
LZS3_k127_9507_2	1267533.KB906736_gene1246	1.184e-183	606.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	204432|Acidobacteriia	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
LZS3_k127_9507_1	204669.Acid345_4118	3.27e-209	681.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria,2JM7T@204432|Acidobacteriia	57723|Acidobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
LZS3_k127_9507_6	1192034.CAP_3762	1.008e-95	344.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria,2YZYM@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,fn3
LZS3_k127_9507_22	1121930.AQXG01000001_gene1216	1.563e-19	104.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Beta_helix,F5_F8_type_C
LZS3_k127_9507_10	247490.KSU1_C0449	4.074e-66	248.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
LZS3_k127_9507_27	518766.Rmar_1069	1.186e-05	58.0	COG3693@1|root,COG3693@2|Bacteria,4NHWH@976|Bacteroidetes	976|Bacteroidetes	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM9_1,CBM_4_9,Glyco_hydro_10,SASA
LZS3_k127_9507_4	234267.Acid_3938	7.736e-122	410.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
## 2991 queries scanned
## Total time (seconds): 60.127299785614014
## Rate: 49.74 q/s