## Mon Nov 11 21:39:05 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/M/MMD1_bin.29.fa -m mmseqs --itype genome -o MMD1_bin.29 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/MMD1_bin.29 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
MMD1_k127_1014324_1	338966.Ppro_0405	1.252e-92	313.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42S7F@68525|delta/epsilon subdivisions,2WK0P@28221|Deltaproteobacteria,43T7X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
MMD1_k127_1014324_3	550540.Fbal_2989	6.757e-11	65.0	arCOG10218@1|root,320QR@2|Bacteria,1N5AN@1224|Proteobacteria	1224|Proteobacteria	C	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
MMD1_k127_1014324_2	550540.Fbal_2989	2.488e-62	220.0	arCOG10218@1|root,320QR@2|Bacteria,1N5AN@1224|Proteobacteria	1224|Proteobacteria	C	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
MMD1_k127_1014324_0	1232410.KI421426_gene1472	8.195e-203	638.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,43U0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
MMD1_k127_1017044_0	1380763.BG53_13020	2.677e-168	543.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26R1I@186822|Paenibacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	lcfA	-	6.2.1.3	ko:K01897,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMD1_k127_1017044_1	243231.GSU0522	9.9e-74	253.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43TW5@69541|Desulfuromonadales	28221|Deltaproteobacteria	JKL	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C,R3H
MMD1_k127_1041015_0	290317.Cpha266_0514	4.998e-136	436.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD1_k127_1041015_3	880072.Desac_1567	8.992e-13	76.0	290YH@1|root,2ZNK8@2|Bacteria,1P7TZ@1224|Proteobacteria,433I3@68525|delta/epsilon subdivisions,2WXS0@28221|Deltaproteobacteria,2MSEA@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1041015_1	1123368.AUIS01000001_gene1900	8.052e-57	225.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,1NRP8@1224|Proteobacteria,1T423@1236|Gammaproteobacteria,2NE6T@225057|Acidithiobacillales	225057|Acidithiobacillales	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_9
MMD1_k127_1041015_2	555779.Dthio_PD0291	3.583e-15	90.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
MMD1_k127_1084689_1	1196322.A370_05533	2.126e-65	239.0	COG0572@1|root,COG5650@1|root,COG0572@2|Bacteria,COG5650@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia	186801|Clostridia	F	Cytidine monophosphokinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
MMD1_k127_1084689_0	344747.PM8797T_32305	7.008e-85	287.0	COG1215@1|root,COG1215@2|Bacteria,2IXXE@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD1_k127_1089026_0	1479237.JMLY01000001_gene3242	1.878e-55	198.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1S65E@1236|Gammaproteobacteria,4681I@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
MMD1_k127_1089026_1	509191.AEDB02000002_gene1179	1.54e-32	130.0	COG2768@1|root,COG2768@2|Bacteria,1UK08@1239|Firmicutes,25FG6@186801|Clostridia,3WK7Y@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
MMD1_k127_1100595_4	56780.SYN_00304	3.574e-135	455.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2X708@28221|Deltaproteobacteria,2MSKI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
MMD1_k127_1100595_6	269799.Gmet_2410	1.474e-94	312.0	COG0605@1|root,COG0605@2|Bacteria,1R4Z3@1224|Proteobacteria,42QV7@68525|delta/epsilon subdivisions,2WMPC@28221|Deltaproteobacteria,43VQC@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Iron/manganese superoxide dismutases, C-terminal domain	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
MMD1_k127_1100595_12	1379698.RBG1_1C00001G1085	6.494e-51	188.0	COG2109@1|root,COG2109@2|Bacteria,2NPNR@2323|unclassified Bacteria	2|Bacteria	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
MMD1_k127_1100595_7	1379281.AVAG01000009_gene602	1.64e-71	251.0	COG3018@1|root,COG3018@2|Bacteria,1R9S8@1224|Proteobacteria,42RI7@68525|delta/epsilon subdivisions,2WP0N@28221|Deltaproteobacteria,2MC12@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
MMD1_k127_1100595_5	96561.Dole_0037	2.907e-100	341.0	COG0457@1|root,COG0457@2|Bacteria,1RKYJ@1224|Proteobacteria,42SSS@68525|delta/epsilon subdivisions,2WPW3@28221|Deltaproteobacteria,2MNI4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
MMD1_k127_1100595_15	56780.SYN_03044	4.053e-40	158.0	COG4254@1|root,COG4254@2|Bacteria,1QVB5@1224|Proteobacteria,42XP1@68525|delta/epsilon subdivisions,2X71D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
MMD1_k127_1100595_14	269799.Gmet_2445	5.676e-48	176.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,43UY7@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMD1_k127_1100595_0	404589.Anae109_2250	3.426e-216	689.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
MMD1_k127_1100595_11	404589.Anae109_2248	5.379e-57	206.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1N3ZM@1224|Proteobacteria,42TUU@68525|delta/epsilon subdivisions,2WQ8Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KP	PFAM iron dependent repressor	ideR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
MMD1_k127_1100595_2	1304885.AUEY01000103_gene2290	3.28e-154	496.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,42PR8@68525|delta/epsilon subdivisions,2WK8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD1_k127_1100595_13	1459636.NTE_02786	3.962e-49	179.0	COG4275@1|root,arCOG10427@2157|Archaea	2157|Archaea	S	Chromate resistance	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
MMD1_k127_1100595_8	589865.DaAHT2_1950	1.782e-71	245.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5Y@1224|Proteobacteria,42SYN@68525|delta/epsilon subdivisions,2WP8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART metal-dependent phosphohydrolase, HD region	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
MMD1_k127_1100595_19	589865.DaAHT2_1950	8.517e-16	81.0	COG1418@1|root,COG1418@2|Bacteria,1RJ5Y@1224|Proteobacteria,42SYN@68525|delta/epsilon subdivisions,2WP8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART metal-dependent phosphohydrolase, HD region	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
MMD1_k127_1100595_3	1403819.BATR01000096_gene3178	2.538e-136	446.0	COG2059@1|root,COG2059@2|Bacteria,46V8S@74201|Verrucomicrobia,2IUYF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Chromate transporter	-	-	-	-	-	-	-	-	-	-	-	-	Chromate_transp
MMD1_k127_1100595_9	706587.Desti_0194	1.378e-70	250.0	COG4275@1|root,COG4275@2|Bacteria,1PKNN@1224|Proteobacteria,42XSF@68525|delta/epsilon subdivisions,2WTCB@28221|Deltaproteobacteria,2MSBS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
MMD1_k127_1100595_18	338966.Ppro_0435	7.891e-25	109.0	COG2204@1|root,COG2204@2|Bacteria,1RKC4@1224|Proteobacteria,42SJ3@68525|delta/epsilon subdivisions,2WPI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_1100595_22	1125863.JAFN01000001_gene387	0.0002242	50.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
MMD1_k127_1100595_16	273068.TTE2627	2.758e-37	146.0	2CA4A@1|root,32RQK@2|Bacteria,1VE2U@1239|Firmicutes,24QHD@186801|Clostridia,42GU9@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
MMD1_k127_1100595_17	269799.Gmet_1931	7.313e-30	123.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions,2WPVC@28221|Deltaproteobacteria,43UWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMD1_k127_1100595_1	290315.Clim_1806	2.667e-210	662.0	COG3278@1|root,COG3278@2|Bacteria,1FER1@1090|Chlorobi	1090|Chlorobi	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
MMD1_k127_1100595_10	653733.Selin_2142	7.601e-61	227.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria	2|Bacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	ccoO	-	1.9.3.1	ko:K00405,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0145	COX1,FixO
MMD1_k127_1100595_21	324925.Ppha_2076	1.652e-08	56.0	2BXBK@1|root,2ZDRS@2|Bacteria,1FFMW@1090|Chlorobi	1090|Chlorobi	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
MMD1_k127_1100595_20	1122621.ATZA01000016_gene3803	3.405e-12	71.0	COG2010@1|root,COG2010@2|Bacteria,4NFMJ@976|Bacteroidetes,1IRZW@117747|Sphingobacteriia	976|Bacteroidetes	C	PFAM Cytochrome c, class I	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
MMD1_k127_1117185_0	1095769.CAHF01000021_gene910	6.441e-181	572.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4729F@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	tctA4	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
MMD1_k127_1117185_4	204773.HEAR0416	3.621e-38	147.0	29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2VT23@28216|Betaproteobacteria,474HM@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	tctB4	-	-	-	-	-	-	-	-	-	-	-	TctB
MMD1_k127_1117185_1	204773.HEAR0415	3.464e-144	465.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,472N8@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	tctC4	-	-	-	-	-	-	-	-	-	-	-	TctC
MMD1_k127_1117185_6	1041139.KB902578_gene5241	5.968e-31	123.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2UC5C@28211|Alphaproteobacteria,4BFST@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
MMD1_k127_1117185_7	1484460.JSWG01000011_gene1676	2.637e-30	132.0	2ENMR@1|root,33G92@2|Bacteria,4P0KF@976|Bacteroidetes,1I7HJ@117743|Flavobacteriia	976|Bacteroidetes	S	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
MMD1_k127_1117185_2	880073.Calab_2887	1.395e-132	436.0	COG2204@1|root,COG2204@2|Bacteria,2NQHI@2323|unclassified Bacteria	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_1117185_5	667014.Thein_0411	4.51e-37	144.0	COG4191@1|root,COG4191@2|Bacteria,2GHNA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS_4,PAS_9
MMD1_k127_114358_1	404589.Anae109_2121	5.144e-51	189.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,2Z010@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
MMD1_k127_114358_0	589865.DaAHT2_2396	5.57e-130	422.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2MKRR@213118|Desulfobacterales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
MMD1_k127_114358_2	589865.DaAHT2_2395	2.705e-05	47.0	COG0484@1|root,COG1426@1|root,COG0484@2|Bacteria,COG1426@2|Bacteria,1NCYU@1224|Proteobacteria,42WS1@68525|delta/epsilon subdivisions,2WSDX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,HTH_25
MMD1_k127_1152835_0	304371.MCP_1463	5.003e-171	545.0	COG0192@1|root,arCOG07444@2157|Archaea	2157|Archaea	H	S-adenosylmethionine synthetase, C-terminal domain	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
MMD1_k127_1193664_3	96561.Dole_1195	2.063e-108	360.0	COG1462@1|root,COG1462@2|Bacteria,1QRM1@1224|Proteobacteria,43A0T@68525|delta/epsilon subdivisions,2X2Q5@28221|Deltaproteobacteria,2MMD7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
MMD1_k127_1193664_4	96561.Dole_1196	3.18e-103	355.0	COG4380@1|root,COG4380@2|Bacteria	2|Bacteria	D	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2
MMD1_k127_1193664_7	123214.PERMA_0018	8.586e-42	163.0	COG1490@1|root,COG1490@2|Bacteria,2G477@200783|Aquificae	200783|Aquificae	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
MMD1_k127_1193664_1	237368.SCABRO_00994	2.687e-165	545.0	COG1199@1|root,COG1199@2|Bacteria,2IX82@203682|Planctomycetes	203682|Planctomycetes	KL	helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
MMD1_k127_1193664_5	404380.Gbem_3145	1.532e-75	259.0	COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,42Q1E@68525|delta/epsilon subdivisions,2WKG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	cog0421, spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
MMD1_k127_1193664_8	945713.IALB_1660	5.086e-33	134.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
MMD1_k127_1193664_6	1317124.DW2_03634	4.171e-42	164.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,2U4F1@28211|Alphaproteobacteria,2XMIG@285107|Thioclava	28211|Alphaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
MMD1_k127_1193664_0	237368.SCABRO_01577	1.654e-202	638.0	COG0498@1|root,COG0498@2|Bacteria,2IXKE@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD1_k127_1193664_2	595460.RRSWK_00838	3.044e-115	383.0	COG0626@1|root,COG0626@2|Bacteria,2IYGK@203682|Planctomycetes	203682|Planctomycetes	E	Cys Met metabolism	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMD1_k127_1193664_9	479437.Elen_1971	1.22e-26	115.0	COG2731@1|root,COG2731@2|Bacteria,2HV2Y@201174|Actinobacteria,4CW7H@84998|Coriobacteriia	84998|Coriobacteriia	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
MMD1_k127_1193664_11	1125863.JAFN01000001_gene3275	9.621e-12	72.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMD1_k127_1193664_14	1321773.HMPREF9069_00086	0.0001481	53.0	COG0745@1|root,COG0745@2|Bacteria,2GNQH@201174|Actinobacteria,4CVNU@84998|Coriobacteriia	84998|Coriobacteriia	K	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
MMD1_k127_1193664_13	867845.KI911784_gene3052	1.507e-09	69.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
MMD1_k127_1193664_10	861299.J421_1792	2.148e-18	90.0	COG2010@1|root,COG2010@2|Bacteria,1ZU6E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
MMD1_k127_1193664_15	112098.XP_008620492.1	0.0005837	53.0	2CMRT@1|root,2QRKV@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
MMD1_k127_1197251_9	243231.GSU3317	4.75e-24	116.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase,YadA_stalk
MMD1_k127_1197251_5	926562.Oweho_3009	6.49e-46	179.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMD1_k127_1197251_6	266117.Rxyl_2050	9.283e-46	169.0	COG0667@1|root,COG0667@2|Bacteria,2H2ID@201174|Actinobacteria,4CR5G@84995|Rubrobacteria	84995|Rubrobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD1_k127_1197251_14	1394178.AWOO02000031_gene4797	2.054e-09	65.0	COG0656@1|root,COG0656@2|Bacteria,2GJQ7@201174|Actinobacteria,4EI0E@85012|Streptosporangiales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	1.1.1.346	ko:K06221	-	-	R08878	RC00089	ko00000,ko01000	-	-	-	Aldo_ket_red
MMD1_k127_1197251_7	1170562.Cal6303_0241	3.277e-31	128.0	COG0667@1|root,COG0667@2|Bacteria,1G1J4@1117|Cyanobacteria,1HS0Q@1161|Nostocales	1117|Cyanobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD1_k127_1197251_0	671143.DAMO_1554	1.076e-129	427.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
MMD1_k127_1197251_2	941639.BCO26_0710	1.174e-85	293.0	COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,4HAAE@91061|Bacilli,1ZPWA@1386|Bacillus	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD1_k127_1197251_12	67267.JNXT01000016_gene3548	1.854e-14	81.0	COG0500@1|root,COG2226@2|Bacteria,2I34F@201174|Actinobacteria	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
MMD1_k127_1197251_4	1340493.JNIF01000003_gene4581	1.102e-52	194.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528,ko:K20444	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko01005,ko02000,ko03009	4.D.1.3	GT2,GT4	-	CTP_transf_like,Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_12,Methyltransf_23,RrnaAD
MMD1_k127_1197251_10	326427.Cagg_1914	1.296e-23	118.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi,376JU@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1197251_11	5911.EAR89871	1.967e-15	91.0	COG3914@1|root,KOG4308@1|root,KOG4308@2759|Eukaryota,KOG4626@2759|Eukaryota	2759|Eukaryota	O	protein N-acetylglucosaminyltransferase activity	-	-	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	TPR_8
MMD1_k127_1197251_8	667014.Thein_1723	3.505e-26	114.0	COG1399@1|root,COG1399@2|Bacteria,2GHV8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
MMD1_k127_1197251_13	439235.Dalk_3305	1.889e-13	77.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,2MMB1@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
MMD1_k127_1197251_1	1499967.BAYZ01000186_gene3963	4.72e-112	372.0	COG0416@1|root,COG0416@2|Bacteria,2NP1H@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15	ko:K03621,ko:K21576,ko:K21577	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
MMD1_k127_1197251_3	90814.KL370891_gene764	2.246e-70	247.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,45ZQP@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
MMD1_k127_1236527_26	1347392.CCEZ01000013_gene2646	1.979e-12	77.0	COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,24B7W@186801|Clostridia,36ESR@31979|Clostridiaceae	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMD1_k127_1236527_13	485913.Krac_9564	7.318e-51	188.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
MMD1_k127_1236527_23	398767.Glov_0916	1.615e-22	98.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria	1224|Proteobacteria	S	Zinc finger cdgsh-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
MMD1_k127_1236527_2	247490.KSU1_C0538	3.708e-129	421.0	COG1741@1|root,COG1741@2|Bacteria,2IXVU@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMD1_k127_1236527_12	1121918.ARWE01000001_gene793	2.669e-54	197.0	COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,437IE@68525|delta/epsilon subdivisions,2WVS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
MMD1_k127_1236527_21	903818.KI912268_gene2176	5.158e-26	108.0	COG3369@1|root,COG3369@2|Bacteria	2|Bacteria	I	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,zf-CDGSH
MMD1_k127_1236527_14	1173026.Glo7428_4661	4.968e-48	176.0	COG1846@1|root,COG1846@2|Bacteria,1G6XI@1117|Cyanobacteria	1117|Cyanobacteria	K	MarR family transcriptional	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
MMD1_k127_1236527_20	1382304.JNIL01000001_gene1439	1.886e-28	124.0	COG1434@1|root,COG1434@2|Bacteria,1V379@1239|Firmicutes,4HG83@91061|Bacilli	91061|Bacilli	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
MMD1_k127_1236527_0	909663.KI867150_gene149	3.069e-189	604.0	COG0477@1|root,COG0477@2|Bacteria,1RGPN@1224|Proteobacteria,43BMI@68525|delta/epsilon subdivisions,2X6ZQ@28221|Deltaproteobacteria,2MQAD@213462|Syntrophobacterales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
MMD1_k127_1236527_3	243231.GSU1481	9.867e-88	298.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42NIC@68525|delta/epsilon subdivisions,2WKV5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMD1_k127_1236527_5	909663.KI867150_gene151	4.65e-80	284.0	COG1538@1|root,COG1538@2|Bacteria,1Q1F4@1224|Proteobacteria,42NUU@68525|delta/epsilon subdivisions,2WK3P@28221|Deltaproteobacteria,2MRMW@213462|Syntrophobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD1_k127_1236527_1	443143.GM18_0198	6.521e-179	574.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WTPN@28221|Deltaproteobacteria,43TVD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE-1	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
MMD1_k127_1236527_24	290397.Adeh_3508	6.902e-18	90.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2WNUH@28221|Deltaproteobacteria,2Z1FH@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	trx-3	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
MMD1_k127_1236527_22	292415.Tbd_2401	1.513e-23	106.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,1KRQZ@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
MMD1_k127_1236527_19	880072.Desac_1081	1.433e-29	122.0	COG0599@1|root,COG0599@2|Bacteria,1N2ZQ@1224|Proteobacteria,42VDR@68525|delta/epsilon subdivisions,2WRKS@28221|Deltaproteobacteria,2MSC8@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMD1_k127_1236527_15	56780.SYN_02524	5.892e-47	173.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42TU6@68525|delta/epsilon subdivisions,2WPZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMD1_k127_1236527_16	667014.Thein_0096	7.075e-40	156.0	2E978@1|root,333FR@2|Bacteria,2GIHH@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1236527_28	521011.Mpal_0137	1.174e-07	59.0	COG0028@1|root,COG1773@1|root,arCOG01999@2157|Archaea,arCOG04391@2157|Archaea,2XWG6@28890|Euryarchaeota	28890|Euryarchaeota	E	Belongs to the TPP enzyme family	-	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	Rubredoxin,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMD1_k127_1236527_25	1336241.JAEB01000010_gene879	2.767e-15	77.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,1V7DF@1239|Firmicutes,24G44@186801|Clostridia,25VSF@186806|Eubacteriaceae	186801|Clostridia	C	Flavin reductase like domain	hrb	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubredoxin
MMD1_k127_1236527_8	909663.KI867150_gene1860	7.515e-72	245.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria,2MQDS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMD1_k127_1236527_6	909663.KI867150_gene1861	6.251e-78	264.0	COG0655@1|root,COG0655@2|Bacteria,1NANP@1224|Proteobacteria,42Q16@68525|delta/epsilon subdivisions,2WIJ7@28221|Deltaproteobacteria,2MQJ5@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,LMWPc
MMD1_k127_1236527_10	880072.Desac_1358	3.255e-61	218.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,42S19@68525|delta/epsilon subdivisions,2WNGU@28221|Deltaproteobacteria,2MRTR@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
MMD1_k127_1236527_17	795359.TOPB45_0801	3.318e-39	151.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	3.6.1.55	ko:K03574,ko:K08296	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1
MMD1_k127_1236527_9	1304885.AUEY01000004_gene925	1.68e-66	228.0	2BC31@1|root,325MS@2|Bacteria,1NBYV@1224|Proteobacteria,431MW@68525|delta/epsilon subdivisions,2WWTC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1236527_18	589865.DaAHT2_0538	1.854e-35	141.0	COG2755@1|root,COG2755@2|Bacteria,1NIYF@1224|Proteobacteria,42XYT@68525|delta/epsilon subdivisions,2WTHB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
MMD1_k127_1236527_4	40571.JOEA01000003_gene3591	5.156e-84	285.0	COG3647@1|root,COG3647@2|Bacteria,2IATE@201174|Actinobacteria,4E3YF@85010|Pseudonocardiales	201174|Actinobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
MMD1_k127_1236527_7	448385.sce7994	1.345e-76	267.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNUR@28221|Deltaproteobacteria,2YUCD@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
MMD1_k127_1236527_11	404589.Anae109_1212	7.067e-61	225.0	COG0204@1|root,COG1022@1|root,COG3320@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,COG3320@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria,2YU6Q@29|Myxococcales	28221|Deltaproteobacteria	IQ	Male sterility protein	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
MMD1_k127_1260022_1	671143.DAMO_1148	2.741e-21	96.0	COG0123@1|root,COG0123@2|Bacteria,2NP8V@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
MMD1_k127_1260022_0	909663.KI867150_gene1265	3.436e-242	762.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MQ7P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMD1_k127_126348_2	243231.GSU1163	4.777e-09	57.0	COG4591@1|root,COG4591@2|Bacteria,1QXNJ@1224|Proteobacteria,43C4I@68525|delta/epsilon subdivisions,2X7EY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD1_k127_126348_0	316067.Geob_2357	1.071e-177	563.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,42NT4@68525|delta/epsilon subdivisions,2WJFM@28221|Deltaproteobacteria,43T76@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD1_k127_126348_3	1121898.Q766_07775	3.508e-08	60.0	2EA3K@1|root,3348M@2|Bacteria,4NWMD@976|Bacteroidetes,1I60W@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_126348_1	1123368.AUIS01000004_gene197	1.054e-105	357.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,1RNZM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in outer membrane biogenesis	yhjG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
MMD1_k127_1273156_3	1347087.CBYO010000005_gene572	9.479e-25	108.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli	91061|Bacilli	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMD1_k127_1273156_4	747365.Thena_1452	3.613e-06	56.0	COG4747@1|root,COG4747@2|Bacteria,1V7U2@1239|Firmicutes,24JE5@186801|Clostridia,42GI5@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
MMD1_k127_1273156_0	1120973.AQXL01000131_gene2040	6.867e-207	661.0	COG3290@1|root,COG3829@1|root,COG3290@2|Bacteria,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,4HADT@91061|Bacilli,27813@186823|Alicyclobacillaceae	91061|Bacilli	KT	Sigma-54 interaction domain	bkdR	-	-	-	-	-	-	-	-	-	-	-	DapB_N,HTH_8,PAS,Sigma54_activat
MMD1_k127_1273156_1	429009.Adeg_0304	8.258e-105	349.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
MMD1_k127_1273156_2	647113.Metok_0415	3.526e-31	130.0	COG0583@1|root,arCOG00224@2157|Archaea,2XVAZ@28890|Euryarchaeota,23QC7@183939|Methanococci	183939|Methanococci	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD1_k127_1289188_0	338966.Ppro_2335	7.911e-65	232.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
MMD1_k127_1289188_2	880073.Calab_1357	5.014e-37	162.0	COG3857@1|root,COG3857@2|Bacteria,2NQ4T@2323|unclassified Bacteria	2|Bacteria	L	PD-(D/E)XK nuclease superfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD_C
MMD1_k127_1289188_4	192952.MM_1652	2.416e-11	67.0	COG1145@1|root,arCOG01610@2157|Archaea,2Y1GK@28890|Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
MMD1_k127_1289188_1	330214.NIDE1582	1.312e-44	164.0	COG3118@1|root,COG3118@2|Bacteria,3J0P6@40117|Nitrospirae	40117|Nitrospirae	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
MMD1_k127_1289188_3	404380.Gbem_3412	4.502e-33	135.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43UYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMD1_k127_129011_8	330214.NIDE3286	8.394e-91	306.0	COG0341@1|root,COG0341@2|Bacteria,3J0GM@40117|Nitrospirae	40117|Nitrospirae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMD1_k127_129011_3	289376.THEYE_A0280	1.704e-146	480.0	COG0342@1|root,COG0342@2|Bacteria,3J09Z@40117|Nitrospirae	40117|Nitrospirae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
MMD1_k127_129011_17	1121396.KB893083_gene441	1.2e-29	121.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2MKCK@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
MMD1_k127_129011_1	293826.Amet_2342	3.231e-156	500.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,36FEZ@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
MMD1_k127_129011_0	443143.GM18_1946	8.451e-185	593.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,43U5S@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
MMD1_k127_129011_12	760568.Desku_0644	6.582e-55	203.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,265M1@186807|Peptococcaceae	186801|Clostridia	J	RNA 2'-O ribose methyltransferase substrate binding	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
MMD1_k127_129011_11	1379281.AVAG01000009_gene607	1.974e-55	198.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MBFU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMD1_k127_129011_13	1297742.A176_01474	8.66e-43	163.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,2YVK3@29|Myxococcales	28221|Deltaproteobacteria	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
MMD1_k127_129011_5	289376.THEYE_A0592	4.189e-122	406.0	COG1030@1|root,COG1030@2|Bacteria,3J0WF@40117|Nitrospirae	40117|Nitrospirae	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
MMD1_k127_129011_7	289376.THEYE_A1475	1.397e-100	334.0	COG0330@1|root,COG0330@2|Bacteria,3J0NF@40117|Nitrospirae	40117|Nitrospirae	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMD1_k127_129011_20	555779.Dthio_PD1004	3.423e-17	85.0	COG4231@1|root,COG4231@2|Bacteria,1N6WI@1224|Proteobacteria,42V3I@68525|delta/epsilon subdivisions,2WRKA@28221|Deltaproteobacteria,2MD6W@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
MMD1_k127_129011_6	289376.THEYE_A1970	1.443e-108	362.0	COG3264@1|root,COG3264@2|Bacteria,3J0R7@40117|Nitrospirae	40117|Nitrospirae	M	Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel
MMD1_k127_129011_19	589865.DaAHT2_2405	3.872e-22	97.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,42VCF@68525|delta/epsilon subdivisions,2WRI6@28221|Deltaproteobacteria,2MNRQ@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
MMD1_k127_129011_10	718252.FP2_23210	4.072e-57	201.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3WITG@541000|Ruminococcaceae	186801|Clostridia	C	Fe-S iron-sulfur cluster assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
MMD1_k127_129011_2	237368.SCABRO_00470	2.253e-150	487.0	COG1104@1|root,COG1104@2|Bacteria,2IXJC@203682|Planctomycetes	203682|Planctomycetes	E	COG1104 Cysteine sulfinate desulfinase cysteine desulfurase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
MMD1_k127_129011_14	926561.KB900617_gene1705	7.908e-41	156.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3WAQ6@53433|Halanaerobiales	186801|Clostridia	K	TIGRFAM transcriptional regulator, Rrf2 family	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
MMD1_k127_129011_15	330214.NIDE2751	6.005e-40	153.0	COG1259@1|root,COG1259@2|Bacteria,3J0RC@40117|Nitrospirae	40117|Nitrospirae	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
MMD1_k127_129011_9	555079.Toce_1347	2.073e-59	212.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,42GQQ@68295|Thermoanaerobacterales	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
MMD1_k127_129011_4	243231.GSU2744	9.151e-130	427.0	COG0477@1|root,COG0477@2|Bacteria,1QWSX@1224|Proteobacteria,43C55@68525|delta/epsilon subdivisions,2X7FI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD1_k127_129011_18	477974.Daud_0675	4.308e-23	114.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,25F8J@186801|Clostridia,2673W@186807|Peptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
MMD1_k127_129011_16	1123376.AUIU01000011_gene1044	1.362e-33	132.0	COG0436@1|root,COG0436@2|Bacteria,3J0EV@40117|Nitrospirae	40117|Nitrospirae	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD1_k127_13167_6	246194.CHY_1226	6.293e-11	64.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,42FRG@68295|Thermoanaerobacterales	186801|Clostridia	C	CO dehydrogenase acetyl-CoA synthase	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
MMD1_k127_13167_1	289376.THEYE_A1473	2.287e-96	322.0	COG1410@1|root,COG1410@2|Bacteria,3J0UH@40117|Nitrospirae	40117|Nitrospirae	H	Pterin binding enzyme	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
MMD1_k127_13167_4	555779.Dthio_PD3219	3.974e-73	256.0	COG5495@1|root,COG5495@2|Bacteria,1RBEZ@1224|Proteobacteria,42PJR@68525|delta/epsilon subdivisions,2WPBQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
MMD1_k127_13167_3	1125863.JAFN01000001_gene2547	6.884e-82	280.0	COG3640@1|root,COG3640@2|Bacteria,1R819@1224|Proteobacteria,42PQR@68525|delta/epsilon subdivisions,2WKE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
MMD1_k127_13167_2	289376.THEYE_A0969	1.363e-92	310.0	COG1351@1|root,COG1351@2|Bacteria	2|Bacteria	F	thymidylate synthase (FAD) activity	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
MMD1_k127_13167_0	370438.PTH_0220	9.03e-100	333.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
MMD1_k127_13167_7	720554.Clocl_2873	1.245e-08	58.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia,3WQ6S@541000|Ruminococcaceae	186801|Clostridia	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
MMD1_k127_13167_5	161156.JQKW01000013_gene179	5.967e-31	126.0	COG0685@1|root,COG2069@1|root,COG0685@2|Bacteria,COG2069@2|Bacteria,2GHER@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CE	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
MMD1_k127_1423434_5	1232410.KI421428_gene1216	5.824e-20	89.0	COG0267@1|root,COG0267@2|Bacteria,1NJ67@1224|Proteobacteria,42V5X@68525|delta/epsilon subdivisions,2WSIR@28221|Deltaproteobacteria,43VP9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
MMD1_k127_1423434_6	671143.DAMO_0526	9.315e-10	62.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
MMD1_k127_1423434_1	644282.Deba_2950	1.908e-67	233.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
MMD1_k127_1423434_2	330214.NIDE1300	1.777e-63	220.0	COG0080@1|root,COG0080@2|Bacteria,3J0K2@40117|Nitrospirae	40117|Nitrospirae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
MMD1_k127_1423434_0	431943.CKL_0213	2.351e-96	321.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,36EF5@31979|Clostridiaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
MMD1_k127_1423434_4	1144275.COCOR_04968	9.494e-44	166.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,42R1J@68525|delta/epsilon subdivisions,2WQE8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
MMD1_k127_1423434_3	384765.SIAM614_16247	4.513e-49	177.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
MMD1_k127_1472066_19	671143.DAMO_0552	7.248e-22	94.0	COG0199@1|root,COG0199@2|Bacteria,2NPW7@2323|unclassified Bacteria	2|Bacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
MMD1_k127_1472066_12	269799.Gmet_0640	2.647e-50	183.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,43V2C@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
MMD1_k127_1472066_9	1341151.ASZU01000021_gene1308	1.071e-54	197.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,27ATZ@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosomal protein L6	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
MMD1_k127_1472066_17	748449.Halha_0205	1.507e-37	144.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3WBWI@53433|Halanaerobiales	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
MMD1_k127_1472066_7	644966.Tmar_2278	2.415e-60	213.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WCJ1@538999|Clostridiales incertae sedis	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
MMD1_k127_1472066_20	1121405.dsmv_3572	2.302e-14	76.0	COG1841@1|root,COG1841@2|Bacteria,1PU2T@1224|Proteobacteria,42WNP@68525|delta/epsilon subdivisions,2WRZZ@28221|Deltaproteobacteria,2MM1B@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
MMD1_k127_1472066_11	858215.Thexy_0353	8.695e-53	190.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,42G84@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
MMD1_k127_1472066_0	289376.THEYE_A1427	9.829e-186	589.0	COG0201@1|root,COG0201@2|Bacteria,3J0C0@40117|Nitrospirae	40117|Nitrospirae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
MMD1_k127_1472066_3	1267533.KB906735_gene5108	6.047e-96	319.0	COG0024@1|root,COG0024@2|Bacteria,3Y2HJ@57723|Acidobacteria,2JI6Z@204432|Acidobacteriia	204432|Acidobacteriia	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
MMD1_k127_1472066_18	1162668.LFE_0905	9.164e-37	142.0	COG0361@1|root,COG0361@2|Bacteria,3J0QB@40117|Nitrospirae	40117|Nitrospirae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
MMD1_k127_1472066_21	1121405.dsmv_3568	2.743e-10	66.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2MM7P@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
MMD1_k127_1472066_14	1161902.HMPREF0378_1141	6.52e-48	175.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3WCJ9@538999|Clostridiales incertae sedis	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
MMD1_k127_1472066_8	338966.Ppro_0704	2.229e-56	199.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2WPH1@28221|Deltaproteobacteria,43UKC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
MMD1_k127_1472066_4	316067.Geob_3600	4.996e-90	302.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
MMD1_k127_1472066_1	404589.Anae109_1938	3.265e-125	410.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2YXN1@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
MMD1_k127_1472066_16	1408823.AXUS01000017_gene1145	3.561e-38	148.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,25RDK@186804|Peptostreptococcaceae	186801|Clostridia	J	50S ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
MMD1_k127_1472066_13	1121405.dsmv_3121	1.38e-48	197.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria,2MMH4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
MMD1_k127_1472066_6	589865.DaAHT2_0405	1.15e-71	253.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,42UZB@68525|delta/epsilon subdivisions,2WQSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
MMD1_k127_1472066_10	1121405.dsmv_3121	1.579e-54	210.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria,2MMH4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
MMD1_k127_1472066_5	1125863.JAFN01000001_gene3034	9.653e-87	308.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HD,Response_reg
MMD1_k127_1472066_15	1121439.dsat_0771	2.616e-46	189.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42QEJ@68525|delta/epsilon subdivisions,2X6C2@28221|Deltaproteobacteria,2MH13@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
MMD1_k127_1472066_2	697281.Mahau_1501	8.371e-108	359.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_1486244_4	1121430.JMLG01000026_gene9	1.23e-89	301.0	COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes,258JQ@186801|Clostridia,2605C@186807|Peptococcaceae	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_1486244_0	243231.GSU2948	3.27e-239	757.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2WKBP@28221|Deltaproteobacteria,43V54@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,Sulfatase
MMD1_k127_1486244_8	1242864.D187_006103	9.236e-33	140.0	COG0515@1|root,COG0515@2|Bacteria,1Q3DQ@1224|Proteobacteria,4395C@68525|delta/epsilon subdivisions,2X4BQ@28221|Deltaproteobacteria,2YYPG@29|Myxococcales	28221|Deltaproteobacteria	KLT	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
MMD1_k127_1486244_10	1242864.D187_006104	6.741e-21	104.0	COG2843@1|root,COG2843@2|Bacteria,1Q3DC@1224|Proteobacteria,4394V@68525|delta/epsilon subdivisions,2X4B3@28221|Deltaproteobacteria,2YYNG@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	-	-	-	-	-	-	-	-	-	PGA_cap
MMD1_k127_1486244_5	984262.SGRA_3571	1.77e-75	265.0	COG0791@1|root,COG0791@2|Bacteria,4NMA0@976|Bacteroidetes	976|Bacteroidetes	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
MMD1_k127_1486244_6	289376.THEYE_A1879	3.659e-42	156.0	COG4802@1|root,COG4802@2|Bacteria	2|Bacteria	C	ferredoxin-thioredoxin reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B,Rhodanese
MMD1_k127_1486244_9	1304885.AUEY01000011_gene1737	4.825e-25	106.0	COG0695@1|root,COG0695@2|Bacteria,1NAZM@1224|Proteobacteria,42VIA@68525|delta/epsilon subdivisions,2WR8X@28221|Deltaproteobacteria,2MKPI@213118|Desulfobacterales	28221|Deltaproteobacteria	O	PFAM Glutaredoxin	-	-	-	ko:K06191	-	-	-	-	ko00000	-	-	-	Glutaredoxin
MMD1_k127_1486244_7	909663.KI867150_gene2081	6.109e-38	151.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,42TQE@68525|delta/epsilon subdivisions,2WQIC@28221|Deltaproteobacteria,2MSI1@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein Slp family	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
MMD1_k127_1486244_2	443144.GM21_0983	1.111e-116	390.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WJ68@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Multi-haem_cyto
MMD1_k127_1486244_12	450851.PHZ_c1595	0.0001707	53.0	COG0823@1|root,COG3710@1|root,COG0823@2|Bacteria,COG3710@2|Bacteria,1NAF2@1224|Proteobacteria,2UF4Q@28211|Alphaproteobacteria,2KJAD@204458|Caulobacterales	204458|Caulobacterales	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Trans_reg_C
MMD1_k127_1486244_1	1123376.AUIU01000011_gene1120	2.791e-183	590.0	COG0029@1|root,COG0029@2|Bacteria,3J0DI@40117|Nitrospirae	40117|Nitrospirae	H	FAD binding domain	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMD1_k127_1486244_3	398767.Glov_0704	3.412e-100	329.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
MMD1_k127_1487702_4	289376.THEYE_A1784	5.069e-22	97.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	MGDG_synth,PHP
MMD1_k127_1487702_1	289376.THEYE_A1783	6.35e-113	378.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	ugcG	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
MMD1_k127_1487702_0	289376.THEYE_A1789	6.743e-184	583.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	bglB	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
MMD1_k127_1487702_3	118005.AWNK01000006_gene1255	1.088e-24	117.0	COG3431@1|root,COG3431@2|Bacteria	2|Bacteria	-	-	pacB	-	-	-	-	-	-	-	-	-	-	-	BLUF,PsiE
MMD1_k127_1487702_2	1234595.C725_0166	2.539e-72	251.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,4BQ0Q@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657,ko:K07659	ko02020,ko02026,map02020,map02026	M00434,M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD1_k127_1487702_5	660470.Theba_1926	1.073e-08	57.0	COG0639@1|root,COG0639@2|Bacteria,2GC5Q@200918|Thermotogae	200918|Thermotogae	T	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
MMD1_k127_1499249_0	671143.DAMO_1396	9.275e-93	316.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,2NNYG@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livM	GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iPC815.YPO3806,iSDY_1059.SDY_3605	ABC_tran,BCA_ABC_TP_C,BPD_transp_2,DUF3382
MMD1_k127_1501501_7	1120985.AUMI01000011_gene35	4.743e-94	316.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4H37S@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
MMD1_k127_1501501_9	580332.Slit_2774	1.513e-42	158.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,44WGK@713636|Nitrosomonadales	28216|Betaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
MMD1_k127_1501501_5	373994.Riv7116_3749	1.736e-102	347.0	COG1397@1|root,COG1397@2|Bacteria,1G30S@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
MMD1_k127_1501501_3	443143.GM18_3859	2.021e-121	396.0	COG0061@1|root,COG0061@2|Bacteria,1NBI3@1224|Proteobacteria,42ZTT@68525|delta/epsilon subdivisions,2WV8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1501501_4	452637.Oter_1041	1.418e-120	396.0	COG0330@1|root,COG0330@2|Bacteria,46U2V@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMD1_k127_1501501_6	1242864.D187_002582	3.006e-98	326.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,42SX4@68525|delta/epsilon subdivisions,2WPWK@28221|Deltaproteobacteria,2YY1W@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
MMD1_k127_1501501_11	1265505.ATUG01000002_gene1127	2.268e-27	119.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1NCEB@1224|Proteobacteria,42ZMD@68525|delta/epsilon subdivisions,2WV10@28221|Deltaproteobacteria,2MNDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1501501_8	316067.Geob_2017	9.283e-58	209.0	COG3267@1|root,COG3267@2|Bacteria,1MYKB@1224|Proteobacteria	1224|Proteobacteria	U	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
MMD1_k127_1501501_1	243231.GSU0564	1.518e-161	519.0	COG2888@1|root,COG2888@2|Bacteria,1MZH3@1224|Proteobacteria,42VBG@68525|delta/epsilon subdivisions,2WTZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1501501_12	1089545.KB913037_gene1626	2.857e-23	106.0	28IPE@1|root,2Z8PE@2|Bacteria,2I9WS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1501501_0	1049564.TevJSym_ax00090	3.01e-238	754.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPCU@1236|Gammaproteobacteria,1J4ET@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	uup	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
MMD1_k127_1501501_10	1265505.ATUG01000002_gene1127	1.96e-34	148.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1NCEB@1224|Proteobacteria,42ZMD@68525|delta/epsilon subdivisions,2WV10@28221|Deltaproteobacteria,2MNDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1501501_13	526222.Desal_2837	3.367e-18	98.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria,2M881@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
MMD1_k127_1501501_2	439235.Dalk_3856	1.045e-142	461.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2MJ60@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
MMD1_k127_1505172_0	760568.Desku_2686	1.327e-93	314.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,260GG@186807|Peptococcaceae	186801|Clostridia	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMD1_k127_1505172_1	404380.Gbem_1946	6.355e-65	226.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42N1A@68525|delta/epsilon subdivisions,2WJ6H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
MMD1_k127_1512927_0	443144.GM21_0509	1.194e-107	357.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMD1_k127_1512927_2	96561.Dole_2785	1.135e-64	233.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2WN8T@28221|Deltaproteobacteria,2MJWP@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
MMD1_k127_1512927_1	289376.THEYE_A1319	3.995e-106	355.0	COG1181@1|root,COG1181@2|Bacteria,3J0JM@40117|Nitrospirae	40117|Nitrospirae	F	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
MMD1_k127_1512927_4	266779.Meso_2003	7.257e-12	76.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,43HJI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	D	Essential cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
MMD1_k127_1512927_3	1121918.ARWE01000001_gene878	1.317e-64	234.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
MMD1_k127_1516279_1	580332.Slit_1176	4.881e-177	576.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria	28216|Betaproteobacteria	S	alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,MG1,Thiol-ester_cl
MMD1_k127_1516279_0	297246.lpp1635	1.839e-249	793.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,1RMBV@1236|Gammaproteobacteria,1JDMR@118969|Legionellales	118969|Legionellales	M	Penicillin-Binding Protein C-terminus Family	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
MMD1_k127_1516279_2	292459.STH568	1.04e-35	145.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
MMD1_k127_1520752_16	690850.Desaf_2301	4.776e-14	72.0	COG0695@1|root,COG0695@2|Bacteria,1P8SJ@1224|Proteobacteria,42XTX@68525|delta/epsilon subdivisions,2WXS8@28221|Deltaproteobacteria,2ME3F@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Glutaredoxin	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
MMD1_k127_1520752_8	909663.KI867150_gene2166	3.054e-57	205.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2MRPA@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD1_k127_1520752_15	909663.KI867150_gene2165	3.172e-23	112.0	COG3170@1|root,COG3170@2|Bacteria,1NHGQ@1224|Proteobacteria,42X64@68525|delta/epsilon subdivisions,2WSMQ@28221|Deltaproteobacteria,2MQPS@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2275,zf-HC2
MMD1_k127_1520752_2	269799.Gmet_0138	9.53e-202	640.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
MMD1_k127_1520752_7	76114.ebA2569	2.562e-61	220.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,2VV97@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
MMD1_k127_1520752_4	269799.Gmet_1189	2.132e-129	429.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,43SCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
MMD1_k127_1520752_11	931626.Awo_c20180	8.296e-43	169.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,25YPZ@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488,ko:K21022	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,PAS_9
MMD1_k127_1520752_3	909663.KI867150_gene853	1.494e-136	439.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,2MR5B@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
MMD1_k127_1520752_1	1123376.AUIU01000014_gene585	1.113e-239	752.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1164	PFOR_II,POR,POR_N,Transketolase_C
MMD1_k127_1520752_5	1123376.AUIU01000016_gene198	3.341e-104	354.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
MMD1_k127_1520752_10	1304885.AUEY01000002_gene330	3.405e-47	184.0	COG1418@1|root,COG1418@2|Bacteria,1RGCM@1224|Proteobacteria,42RC5@68525|delta/epsilon subdivisions,2WNBA@28221|Deltaproteobacteria,2MJS4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMD1_k127_1520752_6	177439.DP2887	4.075e-83	286.0	COG0727@1|root,COG0727@2|Bacteria,1R3YG@1224|Proteobacteria,42NM0@68525|delta/epsilon subdivisions,2WM96@28221|Deltaproteobacteria,2MHSQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
MMD1_k127_1520752_12	579137.Metvu_0034	6.95e-39	152.0	COG1418@1|root,arCOG01858@2157|Archaea,2XY7Y@28890|Euryarchaeota,23R1B@183939|Methanococci	183939|Methanococci	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
MMD1_k127_1520752_9	1123376.AUIU01000013_gene1791	1.371e-50	187.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
MMD1_k127_1520752_0	335543.Sfum_2995	0.0	1004.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,2MQUH@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
MMD1_k127_1520752_14	929562.Emtol_2614	1.953e-24	108.0	COG2905@1|root,COG2905@2|Bacteria,4NP1Y@976|Bacteroidetes,47PPN@768503|Cytophagia	976|Bacteroidetes	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMD1_k127_1520752_13	289376.THEYE_A1829	1.151e-25	108.0	COG1150@1|root,COG2181@1|root,COG1150@2|Bacteria,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	dld	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9,Nitrate_red_gam
MMD1_k127_152335_4	289376.THEYE_A1470	2.585e-58	205.0	COG1614@1|root,COG1614@2|Bacteria	2|Bacteria	C	CO-methylating acetyl-CoA synthase activity	cdhC	-	2.3.1.169	ko:K00193,ko:K14138	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R08433,R09096,R10219,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
MMD1_k127_152335_5	555779.Dthio_PD3232	8.914e-54	194.0	COG1905@1|root,COG1905@2|Bacteria,1RHBU@1224|Proteobacteria,42U8S@68525|delta/epsilon subdivisions,2WQ8V@28221|Deltaproteobacteria,2MAD2@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE-1	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMD1_k127_152335_1	639282.DEFDS_1980	6.09e-243	765.0	COG1894@1|root,COG1894@2|Bacteria,2GF0Z@200930|Deferribacteres	200930|Deferribacteres	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
MMD1_k127_152335_3	555779.Dthio_PD3230	1.127e-149	481.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,43BP2@68525|delta/epsilon subdivisions,2WK8X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	molybdopterin oxidoreductase Fe4S4 region	sfrA	-	1.17.1.10	ko:K05299	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_10,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMD1_k127_152335_2	1449126.JQKL01000004_gene565	5.768e-193	616.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,26AM4@186813|unclassified Clostridiales	186801|Clostridia	C	Molybdopterin oxidoreductase Fe4S4 domain	fdhA2	-	1.17.1.11,1.17.1.9	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMD1_k127_152335_7	401526.TcarDRAFT_2318	4.235e-13	76.0	COG0664@1|root,COG0664@2|Bacteria,1V3XW@1239|Firmicutes,4H41A@909932|Negativicutes	909932|Negativicutes	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMD1_k127_152335_0	1121405.dsmv_1436	0.0	1045.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,42MKE@68525|delta/epsilon subdivisions,2WJF1@28221|Deltaproteobacteria,2MJ0Z@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
MMD1_k127_152335_8	526227.Mesil_3283	3.354e-09	63.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	ABC_tran,MazE_antitoxin
MMD1_k127_152335_6	1122221.JHVI01000042_gene1562	2.369e-31	130.0	COG1848@1|root,COG1848@2|Bacteria,1WNC8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMD1_k127_1524899_2	289376.THEYE_A1058	1.878e-74	271.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
MMD1_k127_1524899_1	404380.Gbem_0410	1.647e-154	494.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,43SYT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
MMD1_k127_1524899_3	644107.SL1157_2582	1.046e-05	53.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,4NC7D@97050|Ruegeria	28211|Alphaproteobacteria	S	Belongs to the HesB IscA family	erpA	-	-	ko:K13628,ko:K15724	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
MMD1_k127_1524899_0	335543.Sfum_3201	1.937e-188	601.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2MQX4@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
MMD1_k127_1524899_4	273526.SMDB11_4282	0.0001668	44.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,401RA@613|Serratia	1236|Gammaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_4275,iECH74115_1262.ECH74115_5243,iECIAI1_1343.ECIAI1_3991,iECO103_1326.ECO103_4362,iECO111_1330.ECO111_4628,iECO26_1355.ECO26_4784,iECSE_1348.ECSE_4086,iEKO11_1354.EKO11_4554,iPC815.YPO3849	Porphobil_deam,Porphobil_deamC
MMD1_k127_1526833_5	443143.GM18_3766	2.867e-09	67.0	COG3156@1|root,COG3156@2|Bacteria,1N9I4@1224|Proteobacteria,42V0N@68525|delta/epsilon subdivisions,2WRR8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM General secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
MMD1_k127_1526833_6	439235.Dalk_5153	2.544e-05	54.0	COG2165@1|root,COG2165@2|Bacteria,1R09J@1224|Proteobacteria,43CSN@68525|delta/epsilon subdivisions,2X80B@28221|Deltaproteobacteria,2MPMU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
MMD1_k127_1526833_4	1232410.KI421418_gene2153	7.541e-12	71.0	COG4967@1|root,COG4967@2|Bacteria,1PSVT@1224|Proteobacteria,43EXX@68525|delta/epsilon subdivisions,2X2IT@28221|Deltaproteobacteria,43VM1@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
MMD1_k127_1526833_3	1232410.KI421418_gene2154	3.199e-15	82.0	COG2165@1|root,COG2165@2|Bacteria,1NZKC@1224|Proteobacteria,430RG@68525|delta/epsilon subdivisions,2WVSQ@28221|Deltaproteobacteria,43V4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1526833_1	1125863.JAFN01000001_gene2967	2.395e-51	188.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
MMD1_k127_1526833_0	448385.sce9217	3.762e-109	366.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
MMD1_k127_1526833_2	868864.Dester_0385	3.498e-21	94.0	COG2804@1|root,COG2804@2|Bacteria,2G4H7@200783|Aquificae	200783|Aquificae	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
MMD1_k127_1532663_2	926569.ANT_14180	2.455e-62	232.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
MMD1_k127_1532663_5	113355.CM001775_gene2675	9.442e-22	107.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria	113355.CM001775_gene2675|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1532663_3	491952.Mar181_2286	1.873e-46	176.0	297A5@1|root,2ZUHQ@2|Bacteria,1MYVB@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4145
MMD1_k127_1532663_1	289376.THEYE_A0155	1.833e-110	368.0	COG0337@1|root,COG0337@2|Bacteria,3J0GA@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
MMD1_k127_1532663_4	1123376.AUIU01000011_gene1075	1.32e-40	157.0	COG0703@1|root,COG0703@2|Bacteria,3J0R8@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
MMD1_k127_1532663_0	243231.GSU2027	1.273e-147	477.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,43U6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
MMD1_k127_1532663_7	1121918.ARWE01000001_gene256	3.167e-05	49.0	COG0775@1|root,COG0775@2|Bacteria,1NDXU@1224|Proteobacteria,42TU4@68525|delta/epsilon subdivisions,2WQX3@28221|Deltaproteobacteria,43UAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
MMD1_k127_1532663_6	316067.Geob_0898	2.91e-09	61.0	COG0775@1|root,COG0775@2|Bacteria,1NDXU@1224|Proteobacteria,42TU4@68525|delta/epsilon subdivisions,2WQX3@28221|Deltaproteobacteria,43U5Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
MMD1_k127_1535941_0	443143.GM18_0414	8.132e-105	352.0	2EWA0@1|root,33PNR@2|Bacteria,1NSPR@1224|Proteobacteria,42YN1@68525|delta/epsilon subdivisions,2WTJI@28221|Deltaproteobacteria,43U3D@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1535941_2	443143.GM18_0688	2.689e-46	174.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43UYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
MMD1_k127_1535941_1	667014.Thein_0765	1.183e-48	189.0	COG0744@1|root,COG0744@2|Bacteria,2GHEW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
MMD1_k127_1539291_35	443143.GM18_2454	9.881e-07	50.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria,43VWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	ATP synthase subunit D	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
MMD1_k127_1539291_5	269799.Gmet_1779	4.941e-121	403.0	COG0526@1|root,COG0526@2|Bacteria,1MWDE@1224|Proteobacteria,42RCT@68525|delta/epsilon subdivisions,2WKJ9@28221|Deltaproteobacteria,43UJX@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
MMD1_k127_1539291_3	272844.PAB1186	8.231e-152	492.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,2433N@183968|Thermococci	183968|Thermococci	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
MMD1_k127_1539291_2	717231.Flexsi_0052	5.692e-175	565.0	COG1155@1|root,COG1155@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
MMD1_k127_1539291_26	443143.GM18_2451	1.302e-24	111.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
MMD1_k127_1539291_25	443143.GM18_2449	2.865e-28	121.0	COG1390@1|root,COG1390@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
MMD1_k127_1539291_29	717231.Flexsi_0048	1.039e-22	99.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
MMD1_k127_1539291_1	443143.GM18_2447	2.711e-180	584.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
MMD1_k127_1539291_9	641491.DND132_1964	2.513e-85	287.0	COG0346@1|root,COG0346@2|Bacteria,1PM7Y@1224|Proteobacteria,42RD3@68525|delta/epsilon subdivisions,2WNY7@28221|Deltaproteobacteria,2M92N@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
MMD1_k127_1539291_11	269797.Mbar_A1603	1.41e-77	273.0	COG0644@1|root,arCOG00570@2157|Archaea,2Y2Q7@28890|Euryarchaeota,2NAKJ@224756|Methanomicrobia	224756|Methanomicrobia	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A1603	FAD_binding_3
MMD1_k127_1539291_22	269799.Gmet_0240	1.251e-30	125.0	COG3357@1|root,COG3357@2|Bacteria,1N7JG@1224|Proteobacteria,42VEP@68525|delta/epsilon subdivisions,2WRD7@28221|Deltaproteobacteria,43VMA@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	transcriptional regulator containing an HTH domain fused to a Zn-ribbon	-	-	-	ko:K07743	-	-	-	-	ko00000	-	-	-	HTH_5
MMD1_k127_1539291_16	1382304.JNIL01000001_gene393	9.937e-46	177.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HAR9@91061|Bacilli,278A2@186823|Alicyclobacillaceae	91061|Bacilli	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
MMD1_k127_1539291_0	1232410.KI421421_gene3599	1.014e-187	603.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,43RZ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PEP-utilising enzyme, N-terminal	ptsI	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
MMD1_k127_1539291_30	207954.MED92_01564	7.719e-22	102.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1XKZ0@135619|Oceanospirillales	135619|Oceanospirillales	G	Phosphocarrier protein HPr	ptsO	-	-	ko:K08485,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1	-	-	PTS-HPr
MMD1_k127_1539291_19	378806.STAUR_7339	9.052e-35	143.0	COG3716@1|root,COG3716@2|Bacteria,1MWTZ@1224|Proteobacteria,42SXR@68525|delta/epsilon subdivisions,2WPQN@28221|Deltaproteobacteria,2YYU5@29|Myxococcales	28221|Deltaproteobacteria	M	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
MMD1_k127_1539291_32	338963.Pcar_1932	8.888e-18	93.0	COG3715@1|root,COG3715@2|Bacteria,1RHFJ@1224|Proteobacteria,42SZF@68525|delta/epsilon subdivisions,2WPSS@28221|Deltaproteobacteria,43SK0@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PTS system sorbose-specific iic component	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
MMD1_k127_1539291_24	1121918.ARWE01000001_gene1881	1.977e-28	120.0	COG3444@1|root,COG3444@2|Bacteria,1R4ES@1224|Proteobacteria,42VCG@68525|delta/epsilon subdivisions,2WRN8@28221|Deltaproteobacteria,43SK6@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
MMD1_k127_1539291_23	1121948.AUAC01000002_gene1759	3.963e-30	123.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,43XZ4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	COG2893 Phosphotransferase system, mannose fructose-specific component IIA	manX	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
MMD1_k127_1539291_10	330214.NIDE1346	4.3e-84	297.0	COG1660@1|root,COG1660@2|Bacteria,3J0IK@40117|Nitrospirae	40117|Nitrospirae	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
MMD1_k127_1539291_15	1144275.COCOR_07138	5.773e-55	203.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,2YUU0@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
MMD1_k127_1539291_21	1131269.AQVV01000003_gene736	1.797e-31	128.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
MMD1_k127_1539291_17	316067.Geob_2281	2.484e-40	163.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,43TY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
MMD1_k127_1539291_4	1232410.KI421421_gene3588	1.17e-131	439.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43RYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-54 factor, Activator interacting domain (AID)	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
MMD1_k127_1539291_7	671143.DAMO_1189	8.563e-95	316.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
MMD1_k127_1539291_28	289376.THEYE_A0231	6.497e-24	109.0	COG1934@1|root,COG1934@2|Bacteria,3J1EG@40117|Nitrospirae	40117|Nitrospirae	S	OstA-like protein	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
MMD1_k127_1539291_34	330214.NIDE1341	1.686e-09	66.0	COG5375@1|root,COG5375@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
MMD1_k127_1539291_13	289376.THEYE_A1020	1.061e-66	240.0	2CB8R@1|root,2Z90U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1539291_14	1232410.KI421424_gene1667	2.358e-57	216.0	28HEC@1|root,2Z7QS@2|Bacteria,1QGH3@1224|Proteobacteria,42WU7@68525|delta/epsilon subdivisions,2WT75@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1539291_36	1304885.AUEY01000003_gene485	1.54e-05	57.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MPM4@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1
MMD1_k127_1539291_31	1521187.JPIM01000068_gene746	2.355e-20	104.0	COG2203@1|root,COG3605@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3920@2|Bacteria,2G67M@200795|Chloroflexi,374WN@32061|Chloroflexia	32061|Chloroflexia	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,HisKA_2
MMD1_k127_1539291_8	1304880.JAGB01000003_gene1124	2.715e-90	310.0	COG1122@1|root,COG1122@2|Bacteria,1UYYS@1239|Firmicutes,25BN3@186801|Clostridia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
MMD1_k127_1539291_33	457570.Nther_1928	1.597e-15	88.0	COG0619@1|root,COG0619@2|Bacteria,1V9T8@1239|Firmicutes,24M7M@186801|Clostridia	186801|Clostridia	P	PFAM Cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
MMD1_k127_1539291_18	457570.Nther_1929	1.39e-35	145.0	COG0310@1|root,COG0310@2|Bacteria,1V6E4@1239|Firmicutes,24MBZ@186801|Clostridia	186801|Clostridia	P	Cobalt uptake substrate-specific transmembrane region	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
MMD1_k127_1539291_27	498761.HM1_1303	2.03e-24	108.0	COG1950@1|root,COG1950@2|Bacteria,1VF4I@1239|Firmicutes,24QRE@186801|Clostridia	186801|Clostridia	S	PFAM Membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
MMD1_k127_1539291_6	243231.GSU1400	3.948e-103	348.0	COG2199@1|root,COG3706@2|Bacteria,1RAKG@1224|Proteobacteria,42QYD@68525|delta/epsilon subdivisions,2WN6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
MMD1_k127_1539291_12	1499967.BAYZ01000147_gene728	5.675e-67	248.0	COG0741@1|root,COG4105@1|root,COG0741@2|Bacteria,COG4105@2|Bacteria,2NPKN@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase SLT domain	slt	-	-	ko:K06381,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
MMD1_k127_1562971_6	1123508.JH636440_gene2371	1.98e-35	142.0	2CCSR@1|root,32RWC@2|Bacteria,2J1M5@203682|Planctomycetes	203682|Planctomycetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMD1_k127_1562971_1	232721.Ajs_3697	1.308e-80	273.0	COG2249@1|root,COG2249@2|Bacteria,1RB3G@1224|Proteobacteria,2WE8J@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
MMD1_k127_1562971_4	1304885.AUEY01000016_gene3049	2.723e-37	146.0	COG0454@1|root,COG0456@2|Bacteria,1PXZG@1224|Proteobacteria,42X4N@68525|delta/epsilon subdivisions,2WTES@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMD1_k127_1562971_5	1122918.KB907291_gene4261	3.046e-36	143.0	COG0454@1|root,COG2318@1|root,COG0456@2|Bacteria,COG2318@2|Bacteria,1V4QC@1239|Firmicutes,4HN2T@91061|Bacilli,26Z4F@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
MMD1_k127_1562971_3	909663.KI867151_gene3123	4.2e-44	181.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
MMD1_k127_1562971_0	316067.Geob_0942	1.284e-131	439.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria	1224|Proteobacteria	G	glucose sorbosone	gdhB	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	CBM_2,GSDH
MMD1_k127_1562971_2	289376.THEYE_A0743	5.931e-65	228.0	COG2204@1|root,COG2204@2|Bacteria,3J10B@40117|Nitrospirae	40117|Nitrospirae	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_1567404_2	688269.Theth_1872	1.041e-25	120.0	COG0501@1|root,COG0501@2|Bacteria,2GCR5@200918|Thermotogae	200918|Thermotogae	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMD1_k127_1567404_1	484019.THA_1091	5.132e-58	208.0	COG1704@1|root,COG1704@2|Bacteria,2GCV5@200918|Thermotogae	200918|Thermotogae	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
MMD1_k127_1567404_0	243231.GSU0454	4.53e-109	361.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria,43TEZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
MMD1_k127_1567404_3	338963.Pcar_3117	9.533e-11	63.0	COG0775@1|root,COG0775@2|Bacteria,1NDXU@1224|Proteobacteria,42TU4@68525|delta/epsilon subdivisions,2WQX3@28221|Deltaproteobacteria,43UAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
MMD1_k127_1582478_2	335543.Sfum_2817	6.156e-97	321.0	COG1136@1|root,COG1136@2|Bacteria,1PFRW@1224|Proteobacteria,42P38@68525|delta/epsilon subdivisions,2WMS9@28221|Deltaproteobacteria,2MRIW@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_1582478_1	398767.Glov_1470	7.94e-117	385.0	28K4S@1|root,2Z9TM@2|Bacteria,1N4AQ@1224|Proteobacteria,42PSN@68525|delta/epsilon subdivisions,2WNF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1582478_0	1125863.JAFN01000001_gene577	4.953e-178	580.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
MMD1_k127_1587943_1	1232410.KI421415_gene3122	1.5e-24	106.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
MMD1_k127_1587943_2	289376.THEYE_A0537	3.245e-10	65.0	COG3937@1|root,COG3937@2|Bacteria	2|Bacteria	-	-	phaI	-	-	-	-	-	-	-	-	-	-	-	Phasin
MMD1_k127_1587943_0	338963.Pcar_2408	1.17e-158	515.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,43THC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
MMD1_k127_1592554_4	1094980.Mpsy_0588	4.766e-20	93.0	COG2002@1|root,arCOG00822@2157|Archaea,2Y1VV@28890|Euryarchaeota,2NB89@224756|Methanomicrobia	224756|Methanomicrobia	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
MMD1_k127_1592554_0	1125863.JAFN01000001_gene365	8.873e-145	468.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
MMD1_k127_1592554_3	269799.Gmet_0588	5.089e-39	163.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
MMD1_k127_1592554_5	933262.AXAM01000084_gene1049	1.309e-10	65.0	COG2331@1|root,COG2331@2|Bacteria,1NGC1@1224|Proteobacteria,42W5D@68525|delta/epsilon subdivisions,2WRAY@28221|Deltaproteobacteria,2MKW8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMD1_k127_1592554_1	1121405.dsmv_0931	1.767e-92	308.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,2MI50@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
MMD1_k127_1592554_2	756499.Desde_3877	5.229e-72	260.0	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,24AIF@186801|Clostridia,261A8@186807|Peptococcaceae	186801|Clostridia	C	PFAM Cysteine-rich domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
MMD1_k127_1592554_6	1123256.KB907925_gene1144	5.33e-08	54.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S66I@1236|Gammaproteobacteria,1X7NR@135614|Xanthomonadales	135614|Xanthomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMD1_k127_1627303_1	335543.Sfum_1479	6.456e-183	580.0	COG2414@1|root,COG2414@2|Bacteria,1NT3Z@1224|Proteobacteria,42MU9@68525|delta/epsilon subdivisions,2WKD2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
MMD1_k127_1627303_2	1304885.AUEY01000003_gene463	1.148e-172	550.0	28M5B@1|root,2ZAJ4@2|Bacteria,1R7Y9@1224|Proteobacteria,42ZPF@68525|delta/epsilon subdivisions,2WUYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1627303_7	596152.DesU5LDRAFT_1309	5.593e-07	55.0	COG2414@1|root,COG2414@2|Bacteria,1NT3Z@1224|Proteobacteria,42MU9@68525|delta/epsilon subdivisions,2WKD2@28221|Deltaproteobacteria,2M7YR@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
MMD1_k127_1627303_5	768671.ThimaDRAFT_0847	1.891e-55	216.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1SA31@1236|Gammaproteobacteria	1224|Proteobacteria	T	SMART ATP-binding region, ATPase-like	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3
MMD1_k127_1627303_4	706587.Desti_2130	1.491e-82	282.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,43AV8@68525|delta/epsilon subdivisions,2X69B@28221|Deltaproteobacteria,2MSKC@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMD1_k127_1627303_6	1158609.I586_01218	1.363e-08	66.0	COG2197@1|root,COG2197@2|Bacteria,1TSBV@1239|Firmicutes,4HC74@91061|Bacilli,4B1QG@81852|Enterococcaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	nreC	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
MMD1_k127_1627303_3	1123392.AQWL01000002_gene1831	1.277e-97	339.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2VHA3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phospholipase, patatin family	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMD1_k127_1627303_0	398767.Glov_3541	8.814e-263	823.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,42P4Z@68525|delta/epsilon subdivisions,2WK24@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_c3_2,FAD_binding_2
MMD1_k127_1636831_1	1123237.Salmuc_03926	2.072e-64	233.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria	2|Bacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.1.1.199	ko:K03438,ko:K13292	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	LGT
MMD1_k127_1636831_0	502025.Hoch_3956	1.784e-108	386.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X816@28221|Deltaproteobacteria,2Z3J5@29|Myxococcales	28221|Deltaproteobacteria	K	sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat,Yop-YscD_cpl
MMD1_k127_1636831_4	864702.OsccyDRAFT_0884	1.354e-09	68.0	COG1716@1|root,COG1716@2|Bacteria,1GDSC@1117|Cyanobacteria,1HFNA@1150|Oscillatoriales	1117|Cyanobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMD1_k127_1636831_3	404589.Anae109_0777	3.526e-57	207.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WP2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
MMD1_k127_1636831_2	880073.Calab_1678	7.558e-64	238.0	COG0515@1|root,COG0515@2|Bacteria,2NPFQ@2323|unclassified Bacteria	2|Bacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,PEGA,Pkinase
MMD1_k127_164561_3	1167006.UWK_01341	2.798e-147	472.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42N63@68525|delta/epsilon subdivisions,2WJPA@28221|Deltaproteobacteria,2MHPB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM nickel-dependent hydrogenase large subunit	mvhL	-	1.12.1.2,1.8.98.5	ko:K00436,ko:K14126	ko00680,map00680	-	R00019,R00700,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
MMD1_k127_164561_8	1167006.UWK_01340	2.995e-117	383.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42U69@68525|delta/epsilon subdivisions,2WQJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase 20 kDa subunit	hyhS	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
MMD1_k127_164561_7	1167006.UWK_01339	1.31e-122	400.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WKKC@28221|Deltaproteobacteria,2MJAK@213118|Desulfobacterales	28221|Deltaproteobacteria	CH	Oxidoreductase FAD-binding domain	hyhG	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
MMD1_k127_164561_4	1167006.UWK_01338	9.042e-142	458.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria,2MI1V@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
MMD1_k127_164561_5	1123373.ATXI01000005_gene900	2.254e-138	462.0	COG1208@1|root,COG3178@1|root,COG1208@2|Bacteria,COG3178@2|Bacteria,2GHXN@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	JM	Ecdysteroid kinase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,NTP_transferase
MMD1_k127_164561_1	289376.THEYE_A0955	5.88e-167	534.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
MMD1_k127_164561_0	264732.Moth_1785	1.975e-185	594.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,42EY1@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R01155,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMD1_k127_164561_11	243231.GSU0540	8.764e-12	70.0	2EE6A@1|root,3380W@2|Bacteria,1NCBW@1224|Proteobacteria,42V9R@68525|delta/epsilon subdivisions,2WSI3@28221|Deltaproteobacteria,43VQV@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_164561_2	269799.Gmet_0063	8.13e-151	486.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,43STU@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
MMD1_k127_164561_9	795359.TOPB45_1259	3.782e-66	232.0	COG0518@1|root,COG0518@2|Bacteria,2GHWA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
MMD1_k127_164561_10	1125863.JAFN01000001_gene2971	5.125e-32	137.0	COG3031@1|root,COG3031@2|Bacteria,1PUWN@1224|Proteobacteria,42T73@68525|delta/epsilon subdivisions,2WR4E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
MMD1_k127_164561_6	1125863.JAFN01000001_gene2970	1.564e-123	419.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
MMD1_k127_164561_12	596153.Alide_0648	1.455e-05	56.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,4AD4K@80864|Comamonadaceae	28216|Betaproteobacteria	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
MMD1_k127_1692659_0	700598.Niako_0486	1.86e-121	422.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
MMD1_k127_1692659_7	1122921.KB898192_gene2065	7.512e-08	66.0	COG2730@1|root,COG4733@1|root,COG2730@2|Bacteria,COG4733@2|Bacteria,1TQB3@1239|Firmicutes,4HU7T@91061|Bacilli,26RV2@186822|Paenibacillaceae	91061|Bacilli	G	Cellulose 1,4-beta-cellobiosidase	bglC3	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Glyco_hydro_48,fn3
MMD1_k127_1692659_6	497965.Cyan7822_0733	2.967e-13	76.0	29Z9K@1|root,30M7T@2|Bacteria,1GM3Q@1117|Cyanobacteria,3KJ43@43988|Cyanothece	1117|Cyanobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
MMD1_k127_1692659_5	1120960.ATXG01000009_gene57	1.796e-13	87.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4FM5W@85023|Microbacteriaceae	201174|Actinobacteria	C	Electron transfer flavoprotein FAD-binding domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
MMD1_k127_1692659_2	945713.IALB_0028	1.736e-33	153.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMD1_k127_1692659_1	747365.Thena_0106	1.823e-36	163.0	COG0644@1|root,COG0644@2|Bacteria,1TRRU@1239|Firmicutes,2481K@186801|Clostridia,42FX5@68295|Thermoanaerobacterales	186801|Clostridia	C	HI0933-like protein	fixC	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thi4
MMD1_k127_1692659_4	96561.Dole_2567	1.788e-23	106.0	2EBR1@1|root,335QY@2|Bacteria,1NA8U@1224|Proteobacteria,42W3V@68525|delta/epsilon subdivisions,2WRH5@28221|Deltaproteobacteria,2MP89@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1692659_3	546273.VEIDISOL_00076	7.977e-28	115.0	COG1489@1|root,COG1833@1|root,COG1489@2|Bacteria,COG1833@2|Bacteria,1V1GZ@1239|Firmicutes,4H3QA@909932|Negativicutes	909932|Negativicutes	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	DUF123,SfsA
MMD1_k127_1712254_4	404589.Anae109_2425	7.545e-09	59.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
MMD1_k127_1712254_5	43989.cce_0713	4.778e-08	64.0	COG0745@1|root,COG0745@2|Bacteria,1G6UJ@1117|Cyanobacteria,3KHX5@43988|Cyanothece	1117|Cyanobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
MMD1_k127_1712254_0	378806.STAUR_1844	1.104e-87	319.0	COG2374@1|root,COG5492@1|root,COG2374@2|Bacteria,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,42UE8@68525|delta/epsilon subdivisions,2WVIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
MMD1_k127_1712254_2	1121456.ATVA01000011_gene1725	7.847e-29	135.0	COG1262@1|root,COG1262@2|Bacteria,1R2HR@1224|Proteobacteria,43DE9@68525|delta/epsilon subdivisions,2X8K7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
MMD1_k127_1712254_3	1051646.VITU9109_05645	8.213e-16	82.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,1SA77@1236|Gammaproteobacteria,1Y122@135623|Vibrionales	135623|Vibrionales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
MMD1_k127_1712254_1	1379698.RBG1_1C00001G0753	2.236e-78	274.0	COG0430@1|root,COG0430@2|Bacteria,2NP9K@2323|unclassified Bacteria	2|Bacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
MMD1_k127_1729640_2	648996.Theam_0136	6.879e-75	254.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMD1_k127_1729640_0	330214.NIDE0260	2.349e-195	616.0	COG1219@1|root,COG1219@2|Bacteria,3J0AM@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
MMD1_k127_1729640_3	1120973.AQXL01000106_gene1867	4.216e-55	199.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli,278G8@186823|Alicyclobacillaceae	91061|Bacilli	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
MMD1_k127_1729640_1	330214.NIDE3049	8.506e-129	417.0	COG1078@1|root,COG1078@2|Bacteria,3J0YB@40117|Nitrospirae	40117|Nitrospirae	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
MMD1_k127_1741104_3	1157490.EL26_17245	4.863e-49	183.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,279RN@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08510	CoaE
MMD1_k127_1741104_0	56780.SYN_00415	2.456e-63	232.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,2MQIX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
MMD1_k127_1741104_2	316067.Geob_1523	3.481e-56	213.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,43T2W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
MMD1_k127_1741104_1	1232410.KI421412_gene445	7.049e-60	214.0	2EWA0@1|root,33PNR@2|Bacteria,1NSPR@1224|Proteobacteria,42YN1@68525|delta/epsilon subdivisions,2WTJI@28221|Deltaproteobacteria,43U3D@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1753253_2	1121403.AUCV01000020_gene3085	1.611e-27	113.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MITK@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMD1_k127_1753253_1	237368.SCABRO_02266	4.649e-54	203.0	COG0500@1|root,COG0500@2|Bacteria,2J4Y5@203682|Planctomycetes	203682|Planctomycetes	KQ	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
MMD1_k127_1753253_3	289376.THEYE_A0216	3.051e-16	88.0	2DU0J@1|root,32UW9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1753253_0	945713.IALB_1398	6.069e-57	206.0	COG0109@1|root,COG0109@2|Bacteria	2|Bacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
MMD1_k127_1766258_1	574087.Acear_0510	9.328e-63	231.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3WB7T@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMD1_k127_1766258_2	338963.Pcar_2144	6.452e-25	112.0	COG4969@1|root,COG4969@2|Bacteria,1Q5KV@1224|Proteobacteria,42UIT@68525|delta/epsilon subdivisions,2WQNS@28221|Deltaproteobacteria,43VIS@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
MMD1_k127_1766258_0	338963.Pcar_2142	1.072e-94	317.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,43RXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_1766258_3	338963.Pcar_2141	0.0004975	47.0	COG1277@1|root,COG1277@2|Bacteria,1RM0H@1224|Proteobacteria,42T8A@68525|delta/epsilon subdivisions,2WPQJ@28221|Deltaproteobacteria,43VJG@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
MMD1_k127_1775052_0	697281.Mahau_1720	6.661e-219	707.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,42EUR@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
MMD1_k127_1775052_1	338966.Ppro_0093	1.457e-152	489.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,43TNF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
MMD1_k127_1775843_4	443143.GM18_3823	6.092e-12	72.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
MMD1_k127_1775843_3	429009.Adeg_0091	1.665e-21	98.0	2DNT5@1|root,32Z0H@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
MMD1_k127_1775843_0	909663.KI867150_gene1749	3.987e-80	274.0	COG0463@1|root,COG0463@2|Bacteria,1QW3P@1224|Proteobacteria,42QT7@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	DUF2304,Glycos_transf_2
MMD1_k127_1775843_1	404380.Gbem_1873	9.744e-43	166.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,43TTA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
MMD1_k127_1775843_2	439235.Dalk_0925	8.173e-30	126.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,42PMQ@68525|delta/epsilon subdivisions,2WKB8@28221|Deltaproteobacteria,2MIF9@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD1_k127_1800258_1	1379698.RBG1_1C00001G1265	4.153e-151	493.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_1800258_4	1379698.RBG1_1C00001G1199	1.165e-58	224.0	COG3852@1|root,COG3852@2|Bacteria,2NS4D@2323|unclassified Bacteria	2|Bacteria	T	Signal transduction histidine kinase, nitrogen specific, NtrB	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9
MMD1_k127_1800258_2	338966.Ppro_0982	3.877e-76	266.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
MMD1_k127_1800258_0	269799.Gmet_1777	7.378e-233	746.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
MMD1_k127_1800258_7	56780.SYN_00885	1.073e-10	76.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria,2MSC9@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
MMD1_k127_1800258_9	639030.JHVA01000001_gene3147	1.521e-05	57.0	COG3391@1|root,COG3391@2|Bacteria,3Y62F@57723|Acidobacteria,2JKD0@204432|Acidobacteriia	204432|Acidobacteriia	S	Cytochrome D1 heme domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
MMD1_k127_1800258_3	1255043.TVNIR_2759	1.643e-71	258.0	COG0577@1|root,COG0577@2|Bacteria,1R5BD@1224|Proteobacteria,1S8BS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD1_k127_1800258_8	96561.Dole_2626	5.043e-10	68.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_2,TPR_7,TPR_8
MMD1_k127_1800258_5	348780.NP_0100A	1.46e-48	181.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,23T7A@183963|Halobacteria	183963|Halobacteria	E	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_1800258_6	56780.SYN_00196	4.033e-15	79.0	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,42XQK@68525|delta/epsilon subdivisions,2WSNS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
MMD1_k127_1814968_3	1347086.CCBA010000023_gene2064	5.33e-23	113.0	COG1404@1|root,COG3291@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,1ZDEQ@1386|Bacillus	91061|Bacilli	O	COG1404 Subtilisin-like serine proteases	bprF	GO:0005575,GO:0005576	-	ko:K13276	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PKD,Peptidase_M6,Peptidase_S8
MMD1_k127_1814968_1	247490.KSU1_D0415	6.154e-80	278.0	COG0620@1|root,COG0620@2|Bacteria,2J2EU@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1814968_2	247490.KSU1_D0415	1.81e-79	278.0	COG0620@1|root,COG0620@2|Bacteria,2J2EU@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1814968_4	1123376.AUIU01000019_gene1240	2.349e-20	102.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	tonB3	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
MMD1_k127_1814968_0	243231.GSU1012	4.293e-96	332.0	COG1906@1|root,COG1906@2|Bacteria,1RAQQ@1224|Proteobacteria,42QZ0@68525|delta/epsilon subdivisions,2WMXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
MMD1_k127_1814968_5	330214.NIDE0789	5.312e-17	83.0	COG0360@1|root,COG0360@2|Bacteria,3J0VS@40117|Nitrospirae	40117|Nitrospirae	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
MMD1_k127_1849566_1	398767.Glov_2787	1.616e-36	142.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
MMD1_k127_1849566_0	429009.Adeg_0173	6.787e-137	450.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,42J66@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02481,ko:K07714,ko:K10943	ko02020,ko05111,map02020,map05111	M00500,M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_1849566_2	1123376.AUIU01000015_gene491	7.753e-34	138.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
MMD1_k127_1849566_3	1162668.LFE_1700	4.02e-21	98.0	COG0838@1|root,COG0838@2|Bacteria,3J0MS@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
MMD1_k127_186367_0	1047013.AQSP01000124_gene2653	4.054e-142	461.0	COG0249@1|root,COG0249@2|Bacteria,2NNN6@2323|unclassified Bacteria	2|Bacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
MMD1_k127_186367_1	243231.GSU0668	2.228e-42	161.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,43V2Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
MMD1_k127_1878252_0	289376.THEYE_A0388	1.013e-156	509.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,3J0XX@40117|Nitrospirae	40117|Nitrospirae	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
MMD1_k127_1880148_1	386456.JQKN01000016_gene920	6.359e-20	96.0	COG1852@1|root,arCOG02078@2157|Archaea,2XXPW@28890|Euryarchaeota,23P2Q@183925|Methanobacteria	183925|Methanobacteria	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
MMD1_k127_1880148_0	1121440.AUMA01000003_gene2988	5.907e-23	106.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,42X7G@68525|delta/epsilon subdivisions,2WSX9@28221|Deltaproteobacteria,2MDSS@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NnrU,PEMT
MMD1_k127_1880148_2	1089547.KB913013_gene2889	0.0001409	46.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,47K15@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
MMD1_k127_1915776_2	1232410.KI421425_gene1548	1.945e-74	256.0	COG0457@1|root,COG0457@2|Bacteria,1N1J2@1224|Proteobacteria,42ZHG@68525|delta/epsilon subdivisions,2WV2W@28221|Deltaproteobacteria,43UR6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1915776_5	1232410.KI421425_gene1547	2.24e-25	110.0	2EQ5T@1|root,32ZV0@2|Bacteria,1NFTI@1224|Proteobacteria,433CK@68525|delta/epsilon subdivisions,2WXC2@28221|Deltaproteobacteria,43VWA@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1915776_1	443143.GM18_4030	2.064e-95	316.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2WQK7@28221|Deltaproteobacteria,43TGA@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
MMD1_k127_1915776_3	443143.GM18_4029	1.564e-63	222.0	COG0848@1|root,COG0848@2|Bacteria,1N8FU@1224|Proteobacteria,42WU3@68525|delta/epsilon subdivisions,2WSMD@28221|Deltaproteobacteria,43UYT@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
MMD1_k127_1915776_4	443144.GM21_0444	5.008e-50	183.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,43V5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
MMD1_k127_1915776_0	1232410.KI421425_gene1543	9.899e-139	456.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,43SUP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
MMD1_k127_1915776_6	768706.Desor_2586	6.485e-20	93.0	COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,2515F@186801|Clostridia,266PU@186807|Peptococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD1_k127_1915776_7	768706.Desor_2586	4.011e-09	59.0	COG0778@1|root,COG0778@2|Bacteria,1V6AG@1239|Firmicutes,2515F@186801|Clostridia,266PU@186807|Peptococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD1_k127_197599_0	269799.Gmet_1864	5.292e-193	611.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WTUB@28221|Deltaproteobacteria,43T1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-1	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
MMD1_k127_197599_2	269799.Gmet_1998	0.0001002	57.0	COG1305@1|root,COG1572@1|root,COG1305@2|Bacteria,COG1572@2|Bacteria,1NZT4@1224|Proteobacteria,4322D@68525|delta/epsilon subdivisions,2WWXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_197599_1	338966.Ppro_1415	4.542e-34	138.0	COG2165@1|root,COG2165@2|Bacteria,1MZ5I@1224|Proteobacteria,42W3H@68525|delta/epsilon subdivisions,2WRRC@28221|Deltaproteobacteria,43V6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretory pathway, pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_1992762_13	1282876.BAOK01000001_gene2205	1.296e-25	108.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria,4BQHF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
MMD1_k127_1992762_6	289376.THEYE_A0090	1.252e-88	299.0	COG1043@1|root,COG1043@2|Bacteria,3J0G6@40117|Nitrospirae	40117|Nitrospirae	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
MMD1_k127_1992762_4	330214.NIDE3039	5.472e-98	327.0	COG3494@1|root,COG3494@2|Bacteria,3J0KP@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
MMD1_k127_1992762_5	243231.GSU2263	7.526e-90	307.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
MMD1_k127_1992762_1	338963.Pcar_1257	8.686e-143	461.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43T8C@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	gnnB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2351	DegT_DnrJ_EryC1
MMD1_k127_1992762_2	269799.Gmet_2350	4.86e-116	385.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,43SZS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
MMD1_k127_1992762_0	880072.Desac_0952	2.968e-175	567.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria,2MQ69@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
MMD1_k127_1992762_12	96561.Dole_2971	6.842e-33	137.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42UW6@68525|delta/epsilon subdivisions,2WQ4A@28221|Deltaproteobacteria,2MJDS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
MMD1_k127_1992762_3	269799.Gmet_2348	8.308e-107	361.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria,43TBC@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
MMD1_k127_1992762_8	671143.DAMO_1643	4.796e-72	256.0	COG1663@1|root,COG1663@2|Bacteria,2NPF0@2323|unclassified Bacteria	2|Bacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396	LpxK
MMD1_k127_1992762_11	1167006.UWK_02835	9.774e-55	198.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MJSF@213118|Desulfobacterales	28221|Deltaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
MMD1_k127_1992762_7	316067.Geob_2111	8.481e-74	263.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMD1_k127_1992762_9	1125863.JAFN01000001_gene533	2.306e-64	229.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,43BK5@68525|delta/epsilon subdivisions,2X6Y1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD1_k127_1992762_10	443144.GM21_3410	3.809e-57	213.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
MMD1_k127_1992762_14	357808.RoseRS_2372	1.183e-13	81.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
MMD1_k127_199939_3	639282.DEFDS_0217	6.232e-61	214.0	COG0705@1|root,COG0705@2|Bacteria,2GFHH@200930|Deferribacteres	200930|Deferribacteres	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMD1_k127_199939_2	1499967.BAYZ01000154_gene1483	4.341e-61	221.0	2CKE1@1|root,32T5C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_199939_1	1125863.JAFN01000001_gene87	5.678e-149	486.0	COG2461@1|root,COG2461@2|Bacteria,1R5J5@1224|Proteobacteria,42QAZ@68525|delta/epsilon subdivisions,2WQTR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
MMD1_k127_199939_4	666684.AfiDRAFT_1073	9.389e-34	138.0	COG0500@1|root,COG2226@2|Bacteria,1MYPU@1224|Proteobacteria,2UD81@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_199939_0	596152.DesU5LDRAFT_0266	1.185e-214	681.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,43AD6@68525|delta/epsilon subdivisions,2WKZE@28221|Deltaproteobacteria,2MGCG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
MMD1_k127_2182793_0	671143.DAMO_0325	3.002e-87	296.0	COG0061@1|root,COG0061@2|Bacteria,2NP7T@2323|unclassified Bacteria	2|Bacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iEcSMS35_1347.EcSMS35_2767,iHN637.CLJU_RS05480,iLJ478.TM1733,iSB619.SA_RS04895	NAD_kinase
MMD1_k127_2182793_2	404380.Gbem_1263	1.749e-38	156.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,42VU4@68525|delta/epsilon subdivisions,2WQBA@28221|Deltaproteobacteria,43V70@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
MMD1_k127_2182793_1	1232410.KI421415_gene3032	3.212e-42	159.0	COG3448@1|root,COG3448@2|Bacteria,1QXNX@1224|Proteobacteria,43C4S@68525|delta/epsilon subdivisions,2X7F6@28221|Deltaproteobacteria,43UYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMD1_k127_2182793_3	1121428.DESHY_160172___1	1.126e-28	117.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,260CR@186807|Peptococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
MMD1_k127_219514_11	1278073.MYSTI_06363	0.0003525	44.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTY9@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_219514_0	289376.THEYE_A2000	5.019e-277	869.0	COG0272@1|root,COG0272@2|Bacteria,3J0W8@40117|Nitrospirae	40117|Nitrospirae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
MMD1_k127_219514_4	926561.KB900623_gene1092	3.595e-74	258.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,3WABN@53433|Halanaerobiales	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
MMD1_k127_219514_3	330214.NIDE1739	5.743e-121	402.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
MMD1_k127_219514_2	1499967.BAYZ01000068_gene1948	2.002e-127	423.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_219514_7	1191523.MROS_1493	1.077e-57	226.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
MMD1_k127_219514_6	237368.SCABRO_00184	8.282e-60	234.0	COG0642@1|root,COG2205@2|Bacteria	237368.SCABRO_00184|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_219514_9	436229.JOEH01000009_gene4447	2.908e-11	75.0	COG0500@1|root,COG2226@2|Bacteria,2IFYW@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	2.1.1.243	ko:K16215	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
MMD1_k127_219514_8	1454004.AW11_01099	1.083e-33	134.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_219514_1	269799.Gmet_2720	2.491e-165	533.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42QCV@68525|delta/epsilon subdivisions,2WJP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMD1_k127_219514_5	1125863.JAFN01000001_gene2998	1.295e-60	216.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WN91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMD1_k127_219514_10	706587.Desti_4616	3.769e-11	72.0	COG2881@1|root,COG2881@2|Bacteria,1N6EP@1224|Proteobacteria,42U9Y@68525|delta/epsilon subdivisions,2WQGR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1,zinc_ribbon_4
MMD1_k127_2195772_1	177437.HRM2_10830	4.383e-190	621.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
MMD1_k127_2195772_0	316067.Geob_0392	0.0	1181.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
MMD1_k127_2195772_15	443144.GM21_3756	1.279e-43	164.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
MMD1_k127_2195772_10	439235.Dalk_1768	2.848e-74	259.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MIZH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
MMD1_k127_2195772_8	330214.NIDE0379	6.99e-80	279.0	COG0564@1|root,COG0564@2|Bacteria,3J0HF@40117|Nitrospirae	40117|Nitrospirae	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMD1_k127_2195772_7	56780.SYN_01411	9.841e-81	280.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2MR0J@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
MMD1_k127_2195772_18	1089548.KI783301_gene2347	1.668e-32	135.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,3WFNQ@539002|Bacillales incertae sedis	91061|Bacilli	L	Staphylococcal nuclease homologues	nucH	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
MMD1_k127_2195772_21	1232410.KI421421_gene3624	1.946e-07	61.0	COG0607@1|root,COG1633@1|root,COG0607@2|Bacteria,COG1633@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
MMD1_k127_2195772_20	713587.THITH_02865	1.357e-18	88.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,1SCJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMD1_k127_2195772_11	1123376.AUIU01000012_gene1591	4.827e-73	254.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
MMD1_k127_2195772_6	330214.NIDE3440	1.432e-96	338.0	COG0457@1|root,COG0457@2|Bacteria,3J0MH@40117|Nitrospirae	40117|Nitrospirae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
MMD1_k127_2195772_9	269799.Gmet_2849	6.424e-76	264.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,43TCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
MMD1_k127_2195772_17	290397.Adeh_0122	6.004e-34	132.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2WQYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
MMD1_k127_2195772_5	671143.DAMO_0507	8.753e-125	407.0	COG0462@1|root,COG0462@2|Bacteria,2NNP6@2323|unclassified Bacteria	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
MMD1_k127_2195772_13	330214.NIDE0782	2.789e-53	196.0	COG1825@1|root,COG1825@2|Bacteria,3J0NK@40117|Nitrospirae	40117|Nitrospirae	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
MMD1_k127_2195772_12	1122216.AUHW01000015_gene2026	1.012e-54	197.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4H4AW@909932|Negativicutes	909932|Negativicutes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
MMD1_k127_2195772_2	243231.GSU0664	1.061e-147	479.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,43T1T@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
MMD1_k127_2195772_16	96561.Dole_1741	2.32e-42	170.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria,2MMKQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
MMD1_k127_2195772_22	338963.Pcar_0504	3.667e-05	52.0	2BP69@1|root,32HXD@2|Bacteria,1Q1KM@1224|Proteobacteria,437BM@68525|delta/epsilon subdivisions,2X2GS@28221|Deltaproteobacteria,43VCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2195772_3	1379270.AUXF01000001_gene2264	1.594e-143	470.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMD1_k127_2195772_14	644282.Deba_2661	1.287e-45	172.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,42VFB@68525|delta/epsilon subdivisions,2WRRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
MMD1_k127_2195772_19	1047013.AQSP01000122_gene2257	8.886e-25	111.0	COG1186@1|root,COG1186@2|Bacteria	2|Bacteria	J	translation release factor activity	prfA3	-	-	-	-	-	-	-	-	-	-	-	RF-1
MMD1_k127_2195772_4	269799.Gmet_0858	1.256e-125	409.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WPDW@28221|Deltaproteobacteria,43U17@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
MMD1_k127_2202920_2	56780.SYN_00283	3.28e-54	197.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P6Q@68525|delta/epsilon subdivisions,2WKPS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_2202920_4	1408813.AYMG01000007_gene4353	9.949e-53	196.0	COG4119@1|root,COG4119@2|Bacteria,4NRRR@976|Bacteroidetes,1ITJZ@117747|Sphingobacteriia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMD1_k127_2202920_0	1125863.JAFN01000001_gene1966	3.168e-172	546.0	COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria	1224|Proteobacteria	U	Beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
MMD1_k127_2202920_1	338966.Ppro_2611	6.881e-137	479.0	COG2202@1|root,COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PJW@68525|delta/epsilon subdivisions,2WJQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
MMD1_k127_2202920_3	247490.KSU1_D0853	1.097e-53	205.0	COG5001@1|root,COG5001@2|Bacteria,2IY4F@203682|Planctomycetes	203682|Planctomycetes	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
MMD1_k127_2212121_1	1304880.JAGB01000001_gene848	1.287e-96	322.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
MMD1_k127_2212121_2	1449126.JQKL01000066_gene2094	1.64e-84	292.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,268C7@186813|unclassified Clostridiales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
MMD1_k127_2212121_0	351160.RCIX1517	7.001e-161	522.0	COG2217@1|root,arCOG02763@1|root,arCOG01576@2157|Archaea,arCOG02763@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia	224756|Methanomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
MMD1_k127_2214818_17	644282.Deba_2273	5.319e-12	68.0	293FK@1|root,2ZQY0@2|Bacteria,1P4ZN@1224|Proteobacteria,432NW@68525|delta/epsilon subdivisions,2WXQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2214818_11	589865.DaAHT2_1598	2.147e-37	150.0	2C5Z2@1|root,32U5Z@2|Bacteria,1N4MT@1224|Proteobacteria,42TX0@68525|delta/epsilon subdivisions,2WQZM@28221|Deltaproteobacteria,2MKYF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
MMD1_k127_2214818_0	909663.KI867150_gene268	3.569e-272	850.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2MQ9X@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup2	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
MMD1_k127_2214818_5	123214.PERMA_1454	4.29e-81	283.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
MMD1_k127_2214818_4	316067.Geob_0764	3.872e-83	283.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2214818_1	316067.Geob_0763	4.472e-121	393.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2214818_10	338969.Rfer_0260	4.961e-44	173.0	COG3005@1|root,COG3005@2|Bacteria,1NBYF@1224|Proteobacteria	1224|Proteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_2214818_20	398767.Glov_2914	7.491e-08	64.0	COG0028@1|root,COG1361@1|root,COG3386@1|root,COG3468@1|root,COG0028@2|Bacteria,COG1361@2|Bacteria,COG3386@2|Bacteria,COG3468@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
MMD1_k127_2214818_14	316067.Geob_1431	1.849e-23	113.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5128,NHL,TPR_11
MMD1_k127_2214818_8	1121918.ARWE01000001_gene829	2.385e-46	182.0	COG3005@1|root,COG3005@2|Bacteria,1NBYF@1224|Proteobacteria,430F8@68525|delta/epsilon subdivisions,2WW0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_2214818_6	443143.GM18_0930	2.407e-80	283.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria,42YES@68525|delta/epsilon subdivisions,2WU80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_2214818_2	483219.LILAB_26365	1.71e-92	326.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
MMD1_k127_2214818_15	1322246.BN4_11311	8.323e-21	108.0	COG1361@1|root,COG1361@2|Bacteria,1R5HW@1224|Proteobacteria,42R1Y@68525|delta/epsilon subdivisions,2WMXD@28221|Deltaproteobacteria,2M8MB@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
MMD1_k127_2214818_16	1423806.JCM15457_1236	8.045e-19	100.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,4HAFZ@91061|Bacilli,3F60D@33958|Lactobacillaceae	91061|Bacilli	N	FliG middle domain	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
MMD1_k127_2214818_9	644282.Deba_2308	6.612e-46	175.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42PR1@68525|delta/epsilon subdivisions,2WIQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
MMD1_k127_2214818_13	867903.ThesuDRAFT_01853	5.999e-32	134.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,3WDNX@538999|Clostridiales incertae sedis	186801|Clostridia	N	OmpA family	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
MMD1_k127_2214818_12	1117379.BABA_22643	1.184e-33	145.0	COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,1ZB4F@1386|Bacillus	91061|Bacilli	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
MMD1_k127_2214818_21	247490.KSU1_A0013	4.98e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,2J3FA@203682|Planctomycetes	203682|Planctomycetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
MMD1_k127_2214818_7	404380.Gbem_1124	3.425e-78	280.0	COG3043@1|root,COG3043@2|Bacteria,1QXP6@1224|Proteobacteria,43C52@68525|delta/epsilon subdivisions,2X7FE@28221|Deltaproteobacteria,43W47@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_2214818_3	316067.Geob_0763	3.584e-83	284.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2247265_2	550540.Fbal_3355	1.996e-13	74.0	COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1SGG7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
MMD1_k127_2247265_3	744980.TRICHSKD4_0194	2.987e-09	63.0	2DN6U@1|root,32VVA@2|Bacteria,1N6AG@1224|Proteobacteria,2TZ4M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cysteine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_FGFR
MMD1_k127_2247265_0	945713.IALB_1305	1.93e-132	439.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
MMD1_k127_2247265_1	1202962.KB907155_gene2968	4.973e-115	379.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
MMD1_k127_224798_0	314278.NB231_01773	2.725e-165	524.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,1RPDE@1236|Gammaproteobacteria,1WWMT@135613|Chromatiales	135613|Chromatiales	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
MMD1_k127_224798_1	1454004.AW11_02387	9.44e-165	532.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2VHI3@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Outer membrane protein transport protein, Ompp1 FadL TodX	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
MMD1_k127_224798_3	497964.CfE428DRAFT_1145	3.471e-26	117.0	COG1226@1|root,32Y28@2|Bacteria,46T92@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
MMD1_k127_224798_2	926550.CLDAP_10820	6.774e-28	121.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	Lipoprotein_21,META,YscW
MMD1_k127_2250822_2	537970.HCAN_1093	2.768e-44	167.0	COG3043@1|root,COG3043@2|Bacteria,1NAZB@1224|Proteobacteria,42SN1@68525|delta/epsilon subdivisions,2YPF9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB	napB	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	NapB
MMD1_k127_2250822_4	1158345.JNLL01000001_gene1249	5.201e-21	95.0	COG3062@1|root,COG3062@2|Bacteria	2|Bacteria	P	negative regulation of establishment of protein localization	napD	GO:0003674,GO:0005048,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032879,GO:0032880,GO:0033218,GO:0042277,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0051049,GO:0051051,GO:0051223,GO:0051224,GO:0065007,GO:0070201,GO:0090087,GO:1904950	-	ko:K02570	-	-	-	-	ko00000	-	-	-	NapD
MMD1_k127_2250822_1	667014.Thein_0586	1.709e-75	259.0	COG2191@1|root,COG2191@2|Bacteria,2GICJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE
MMD1_k127_2250822_3	443143.GM18_4465	2.568e-32	129.0	COG2005@1|root,COG2005@2|Bacteria,1MZ31@1224|Proteobacteria,42NA0@68525|delta/epsilon subdivisions,2WRTB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
MMD1_k127_2250822_0	589865.DaAHT2_0550	3.104e-94	323.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MITK@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMD1_k127_225091_24	1123405.AUMM01000075_gene133	1.683e-10	65.0	2DTS4@1|root,33MFD@2|Bacteria,1VKHK@1239|Firmicutes,4I120@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_225091_3	316067.Geob_3588	2.832e-166	532.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,43TMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
MMD1_k127_225091_22	767817.Desgi_2021	4.605e-18	89.0	COG2138@1|root,COG2138@2|Bacteria,1TRDV@1239|Firmicutes,24QUN@186801|Clostridia,262UA@186807|Peptococcaceae	186801|Clostridia	S	PFAM cobalamin (vitamin B12) biosynthesis CbiX	cbiX	-	4.99.1.3,4.99.1.4	ko:K03794,ko:K03795	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R05807	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
MMD1_k127_225091_23	909663.KI867150_gene1680	5.517e-17	88.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MQME@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
MMD1_k127_225091_11	1232410.KI421416_gene2597	9.477e-82	301.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,43S5P@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	TIGRFAM riboflavin biosynthesis protein RibF	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
MMD1_k127_225091_6	1232410.KI421416_gene2600	2.103e-120	401.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42NTB@68525|delta/epsilon subdivisions,2WKNX@28221|Deltaproteobacteria,43U98@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
MMD1_k127_225091_4	246194.CHY_0280	3.602e-146	469.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
MMD1_k127_225091_2	330214.NIDE1106	1.124e-179	570.0	COG0126@1|root,COG0126@2|Bacteria,3J0DE@40117|Nitrospirae	40117|Nitrospirae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
MMD1_k127_225091_10	1123288.SOV_3c01670	2.564e-94	316.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4H27A@909932|Negativicutes	909932|Negativicutes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
MMD1_k127_225091_21	316067.Geob_2900	3.75e-20	93.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,43V72@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
MMD1_k127_225091_0	243231.GSU1433	1.202e-212	672.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43U0I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
MMD1_k127_225091_8	1382306.JNIM01000001_gene660	4.024e-117	385.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMD1_k127_225091_12	1121472.AQWN01000010_gene533	3.397e-70	246.0	COG0842@1|root,COG0842@2|Bacteria,1UYEB@1239|Firmicutes,24BUQ@186801|Clostridia,261NQ@186807|Peptococcaceae	186801|Clostridia	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMD1_k127_225091_18	497964.CfE428DRAFT_5036	1.979e-33	135.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
MMD1_k127_225091_5	330214.NIDE1215	4.604e-139	449.0	COG0407@1|root,COG0407@2|Bacteria,3J0C3@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
MMD1_k127_225091_14	309801.trd_1383	1.778e-54	203.0	COG0276@1|root,COG0276@2|Bacteria,2G6A2@200795|Chloroflexi,27XJN@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
MMD1_k127_225091_1	243232.MJ_1479	4.789e-187	593.0	COG0436@1|root,arCOG01135@2157|Archaea,2XVMM@28890|Euryarchaeota,23QBY@183939|Methanococci	183939|Methanococci	E	PFAM aminotransferase, class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
MMD1_k127_225091_7	246194.CHY_0481	8.521e-118	395.0	COG1232@1|root,COG1232@2|Bacteria,1TQ6W@1239|Firmicutes,24IHQ@186801|Clostridia	186801|Clostridia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
MMD1_k127_225091_16	330214.NIDE4308	3.626e-35	138.0	COG0824@1|root,COG0824@2|Bacteria,3J1EV@40117|Nitrospirae	40117|Nitrospirae	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
MMD1_k127_225091_15	1304874.JAFY01000007_gene1922	8.49e-47	179.0	COG4123@1|root,COG4123@2|Bacteria,3TAVY@508458|Synergistetes	508458|Synergistetes	S	methyltransferase small	-	-	-	-	-	-	-	-	-	-	-	-	MTS,Methyltransf_31
MMD1_k127_225091_9	697282.Mettu_0616	1.538e-108	364.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
MMD1_k127_225091_20	1415780.JPOG01000001_gene1595	2.959e-22	100.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1SAUS@1236|Gammaproteobacteria,1X738@135614|Xanthomonadales	135614|Xanthomonadales	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
MMD1_k127_225091_13	1499967.BAYZ01000145_gene6207	5.878e-64	228.0	COG1028@1|root,COG1028@2|Bacteria,2NQVU@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
MMD1_k127_225091_17	156889.Mmc1_0329	6.663e-35	136.0	COG1539@1|root,COG1539@2|Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
MMD1_k127_225091_19	397948.Cmaq_0517	4.461e-33	138.0	COG0801@1|root,arCOG07203@2157|Archaea	2157|Archaea	H	Dihydroneopterin aldolase	-	-	-	-	-	-	-	-	-	-	-	-	FolB,HPPK
MMD1_k127_225823_2	671143.DAMO_0677	1.228e-86	289.0	COG1186@1|root,COG1186@2|Bacteria,2NNU3@2323|unclassified Bacteria	2|Bacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMD1_k127_225823_5	105559.Nwat_0046	1.238e-33	138.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1X28T@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMD1_k127_225823_1	1123371.ATXH01000008_gene241	1.329e-95	335.0	COG0860@1|root,COG0860@2|Bacteria,2GH8K@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
MMD1_k127_225823_4	1291050.JAGE01000001_gene531	1.008e-40	154.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3WIYY@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
MMD1_k127_225823_7	580331.Thit_1520	3.351e-09	60.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,42H52@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
MMD1_k127_225823_3	635013.TherJR_1877	5.278e-63	220.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,260V8@186807|Peptococcaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
MMD1_k127_225823_0	1123371.ATXH01000013_gene1505	2.604e-254	799.0	COG0441@1|root,COG0441@2|Bacteria,2GH53@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
MMD1_k127_225823_6	243231.GSU0684	1.453e-21	95.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42SH0@68525|delta/epsilon subdivisions,2WPFU@28221|Deltaproteobacteria,43UNN@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
MMD1_k127_2260670_1	314278.NB231_10523	4.762e-65	224.0	COG1980@1|root,COG1980@2|Bacteria,1MXM7@1224|Proteobacteria,1SKUG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P)	-	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
MMD1_k127_2260670_0	404380.Gbem_0265	1.335e-144	470.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
MMD1_k127_2282393_1	56110.Oscil6304_2815	1.114e-73	265.0	COG1404@1|root,COG1520@1|root,COG2931@1|root,COG4733@1|root,COG4935@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1G342@1117|Cyanobacteria,1HH6R@1150|Oscillatoriales	1117|Cyanobacteria	O	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP
MMD1_k127_2282393_0	304371.MCP_1993	3.481e-95	326.0	COG4032@1|root,arCOG01614@2157|Archaea,2XVNH@28890|Euryarchaeota,2N9BM@224756|Methanomicrobia	224756|Methanomicrobia	G	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	comD/comE	-	4.1.1.79	ko:K13039	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
MMD1_k127_2282393_2	351160.LRC440	4.192e-67	237.0	COG0498@1|root,arCOG01434@2157|Archaea,2XUJC@28890|Euryarchaeota,2N9BY@224756|Methanomicrobia	224756|Methanomicrobia	H	Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate	-	-	2.5.1.76	ko:K15527	-	-	-	-	ko00000,ko01000	-	-	-	PALP
MMD1_k127_2283292_14	329726.AM1_2208	6.985e-74	253.0	COG4106@1|root,COG4106@2|Bacteria,1G8SS@1117|Cyanobacteria	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
MMD1_k127_2283292_13	1123401.JHYQ01000025_gene3314	3.653e-76	263.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,1RMZ7@1236|Gammaproteobacteria,46208@72273|Thiotrichales	72273|Thiotrichales	J	RNA pseudouridylate synthase	-	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
MMD1_k127_2283292_8	56780.SYN_00061	5.937e-107	368.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2MQCA@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
MMD1_k127_2283292_3	56780.SYN_00253	9.331e-183	578.0	COG1812@1|root,COG1812@2|Bacteria,1QPB9@1224|Proteobacteria,42YHC@68525|delta/epsilon subdivisions,2WTU3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM S-adenosylmethionine synthetase (MAT)	metK-2	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_Synthase
MMD1_k127_2283292_24	589865.DaAHT2_1730	1.092e-39	151.0	COG3794@1|root,COG3794@2|Bacteria,1N0BX@1224|Proteobacteria,431VB@68525|delta/epsilon subdivisions,2WX3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2283292_6	404380.Gbem_0272	1.28e-158	527.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg,dCache_1
MMD1_k127_2283292_12	1237149.C900_02556	2.025e-76	274.0	COG0554@1|root,COG0554@2|Bacteria,4NFUH@976|Bacteroidetes,47KFD@768503|Cytophagia	976|Bacteroidetes	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	DAO,DAO_C,FGGY_C,FGGY_N
MMD1_k127_2283292_27	1236689.MMALV_03370	3.09e-29	125.0	COG0535@1|root,arCOG00956@2157|Archaea,arCOG02736@2157|Archaea,2XU9R@28890|Euryarchaeota	28890|Euryarchaeota	S	Radical SAM domain protein	nifB	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Fer4_14,Nitro_FeMo-Co,Radical_SAM
MMD1_k127_2283292_7	498761.HM1_0866	3.398e-149	476.0	COG1348@1|root,COG1348@2|Bacteria,1TPXR@1239|Firmicutes,247KJ@186801|Clostridia	186801|Clostridia	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1,1.3.7.14,1.3.7.15,1.3.7.7	ko:K02588,ko:K04037,ko:K11333	ko00625,ko00860,ko00910,ko01100,ko01110,ko01120,map00625,map00860,map00910,map01100,map01110,map01120	M00175	R05185,R05496,R06282,R09053,R09060	RC00002,RC01008,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
MMD1_k127_2283292_1	289376.THEYE_A1716	4.079e-239	745.0	COG2710@1|root,COG2710@2|Bacteria,3J0ZE@40117|Nitrospirae	40117|Nitrospirae	C	Nitrogenase component 1 type Oxidoreductase	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
MMD1_k127_2283292_2	289376.THEYE_A1715	4.18e-225	708.0	COG2710@1|root,COG2710@2|Bacteria,3J0WI@40117|Nitrospirae	40117|Nitrospirae	F	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
MMD1_k127_2283292_0	289376.THEYE_A1714	1.567e-291	919.0	COG2710@1|root,COG2710@2|Bacteria,3J0WK@40117|Nitrospirae	40117|Nitrospirae	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
MMD1_k127_2283292_23	289376.THEYE_A1713	1.059e-43	162.0	COG1433@1|root,COG1433@2|Bacteria,3J1D3@40117|Nitrospirae	40117|Nitrospirae	S	Dinitrogenase iron-molybdenum cofactor	nifX	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
MMD1_k127_2283292_18	289376.THEYE_A1712	3.751e-53	189.0	COG0347@1|root,COG0347@2|Bacteria,3J172@40117|Nitrospirae	40117|Nitrospirae	K	Nitrogen regulatory protein P-II	-	-	-	ko:K02589	-	-	-	-	ko00000	-	-	-	P-II
MMD1_k127_2283292_19	289376.THEYE_A1711	1.301e-52	188.0	COG0347@1|root,COG0347@2|Bacteria,3J17E@40117|Nitrospirae	40117|Nitrospirae	K	Nitrogen regulatory protein P-II	-	-	-	ko:K02590	-	-	-	-	ko00000	-	-	-	P-II
MMD1_k127_2283292_26	211165.AJLN01000104_gene6558	3.32e-33	130.0	COG4231@1|root,COG4231@2|Bacteria,1GQ0I@1117|Cyanobacteria,1JIVS@1189|Stigonemataceae	1117|Cyanobacteria	C	4Fe-4S dicluster domain	fdxB	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
MMD1_k127_2283292_25	243233.MCA0119	2.261e-37	145.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,1SZ10@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMD1_k127_2283292_9	289376.THEYE_A1710	1.747e-95	321.0	COG0535@1|root,COG0535@2|Bacteria,3J108@40117|Nitrospirae	40117|Nitrospirae	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Radical_SAM
MMD1_k127_2283292_16	909663.KI867150_gene1462	1.131e-61	222.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,42MZE@68525|delta/epsilon subdivisions,2WKJB@28221|Deltaproteobacteria,2MQEW@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iAF987.Gmet_0512	SBP_bac_11
MMD1_k127_2283292_10	880072.Desac_1059	8.976e-93	309.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,42NZV@68525|delta/epsilon subdivisions,2WKDG@28221|Deltaproteobacteria,2MQD7@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
MMD1_k127_2283292_11	880072.Desac_1058	5.662e-77	265.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,42MSG@68525|delta/epsilon subdivisions,2X7QQ@28221|Deltaproteobacteria,2MQG8@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	ABC transporter	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
MMD1_k127_2283292_17	69014.TK0283	1.885e-54	207.0	COG0119@1|root,arCOG02092@2157|Archaea,2XSZJ@28890|Euryarchaeota,243R2@183968|Thermococci	183968|Thermococci	E	homocitrate synthase activity	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
MMD1_k127_2283292_15	204669.Acid345_4447	1.626e-64	237.0	COG2067@1|root,COG2067@2|Bacteria,3Y3JJ@57723|Acidobacteria,2JJB9@204432|Acidobacteriia	204432|Acidobacteriia	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
MMD1_k127_2283292_5	547144.HydHO_0931	1.498e-159	516.0	COG0004@1|root,COG0004@2|Bacteria,2G3NI@200783|Aquificae	200783|Aquificae	P	Ammonium Transporter	amtB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMD1_k127_2283292_21	243231.GSU1836	5.43e-49	177.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,43V1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
MMD1_k127_2283292_4	335543.Sfum_0727	2.091e-175	560.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2MRAX@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
MMD1_k127_2283292_22	913865.DOT_0559	7.774e-47	181.0	COG0697@1|root,COG0697@2|Bacteria,1V65P@1239|Firmicutes	1239|Firmicutes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD1_k127_2283292_20	671143.DAMO_0859	6.037e-52	194.0	COG3852@1|root,COG3852@2|Bacteria,2NS4D@2323|unclassified Bacteria	2|Bacteria	T	Signal transduction histidine kinase, nitrogen specific, NtrB	gnfL	-	2.7.13.3	ko:K07708,ko:K10942	ko02020,ko05111,map02020,map05111	M00497,M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
MMD1_k127_2284093_9	335543.Sfum_2815	1.405e-36	143.0	COG4314@1|root,COG4314@2|Bacteria,1RID8@1224|Proteobacteria,42SYX@68525|delta/epsilon subdivisions,2WPEE@28221|Deltaproteobacteria,2MSFE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
MMD1_k127_2284093_7	1121405.dsmv_2958	3.501e-46	171.0	COG4314@1|root,COG4314@2|Bacteria,1N43A@1224|Proteobacteria,42U7U@68525|delta/epsilon subdivisions,2WQYI@28221|Deltaproteobacteria,2MMFG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
MMD1_k127_2284093_8	1009370.ALO_06180	9.88e-38	150.0	COG0778@1|root,COG0778@2|Bacteria,1V2D6@1239|Firmicutes,4H46P@909932|Negativicutes	909932|Negativicutes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD1_k127_2284093_0	748727.CLJU_c14780	2.905e-147	473.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,36DMI@31979|Clostridiaceae	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
MMD1_k127_2284093_6	1177181.T9A_00742	3.283e-50	190.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,1RNKH@1236|Gammaproteobacteria,1XJSY@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
MMD1_k127_2284093_2	484770.UFO1_1280	4.313e-105	350.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4H1XK@909932|Negativicutes	909932|Negativicutes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
MMD1_k127_2284093_1	643562.Daes_1050	1.088e-138	460.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,2M8JP@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
MMD1_k127_2284093_4	316067.Geob_2265	7.843e-59	212.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42SH0@68525|delta/epsilon subdivisions,2WPFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
MMD1_k127_2284093_11	1121406.JAEX01000017_gene1915	1.03e-11	71.0	COG2204@1|root,COG2204@2|Bacteria,1P58Q@1224|Proteobacteria,430GN@68525|delta/epsilon subdivisions,2WVMH@28221|Deltaproteobacteria,2MCHQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_2284093_3	483219.LILAB_29405	7.835e-105	356.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_2284093_5	398767.Glov_3520	4.745e-57	205.0	COG3614@1|root,COG3852@1|root,COG4251@1|root,COG3614@2|Bacteria,COG3852@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,dCache_1
MMD1_k127_2317756_3	290397.Adeh_2129	6.422e-14	83.0	2DGGU@1|root,2ZVXA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2317756_4	243231.GSU3016	1.05e-08	67.0	COG0823@1|root,COG2885@1|root,COG3291@1|root,COG4412@1|root,COG5492@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,COG5492@2|Bacteria,1PMFY@1224|Proteobacteria,42Y8D@68525|delta/epsilon subdivisions,2WUNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
MMD1_k127_2317756_1	515635.Dtur_1285	4.595e-46	189.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
MMD1_k127_2317756_0	269799.Gmet_2594	7.302e-94	320.0	COG3240@1|root,COG3240@2|Bacteria,1MWDI@1224|Proteobacteria,42WSP@68525|delta/epsilon subdivisions,2WS6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
MMD1_k127_2317756_2	1121272.KB903283_gene5063	1.033e-15	88.0	COG4932@1|root,COG4932@2|Bacteria,2HVVN@201174|Actinobacteria,4DHY1@85008|Micromonosporales	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2320815_2	96561.Dole_2460	1.347e-49	190.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2320815_1	251221.35212674	4.388e-119	391.0	COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria	1117|Cyanobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
MMD1_k127_2320815_4	1034347.CAHJ01000044_gene4882	1.691e-07	59.0	COG2044@1|root,COG2044@2|Bacteria,1UA45@1239|Firmicutes,4IKDW@91061|Bacilli,1ZGNG@1386|Bacillus	91061|Bacilli	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
MMD1_k127_2320815_5	1220534.B655_1104	5.163e-05	52.0	COG0589@1|root,arCOG02053@2157|Archaea,2XX4T@28890|Euryarchaeota	28890|Euryarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_2320815_0	909663.KI867149_gene3191	3.338e-259	812.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2WK62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
MMD1_k127_2320815_3	1122604.JONR01000012_gene3401	7.2e-13	68.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,1S4M7@1236|Gammaproteobacteria,1X6D4@135614|Xanthomonadales	135614|Xanthomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMD1_k127_2330565_6	324602.Caur_2652	5.673e-69	250.0	COG0515@1|root,COG0515@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMD1_k127_2330565_10	797114.C475_06540	1.555e-28	134.0	COG2304@1|root,arCOG03991@1|root,arCOG09176@1|root,arCOG02902@2157|Archaea,arCOG03991@2157|Archaea,arCOG09176@2157|Archaea,2XVVH@28890|Euryarchaeota,23SGN@183963|Halobacteria	183963|Halobacteria	K	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
MMD1_k127_2330565_11	316274.Haur_4044	5.368e-26	113.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
MMD1_k127_2330565_3	765420.OSCT_0378	8.202e-93	319.0	COG2304@1|root,COG2304@2|Bacteria,2G82P@200795|Chloroflexi,374S6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
MMD1_k127_2330565_8	316274.Haur_4042	6.808e-48	184.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi,375G5@32061|Chloroflexia	32061|Chloroflexia	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
MMD1_k127_2330565_9	204669.Acid345_2866	3.136e-47	186.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,3Y52R@57723|Acidobacteria	57723|Acidobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2330565_13	1121422.AUMW01000020_gene1706	8.368e-10	65.0	COG1366@1|root,COG1366@2|Bacteria,1VXP2@1239|Firmicutes	1239|Firmicutes	T	STAS domain	-	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS,STAS_2
MMD1_k127_2330565_12	933262.AXAM01000057_gene1532	3.525e-12	79.0	2EVWS@1|root,33PAF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2330565_4	1125863.JAFN01000001_gene381	2.974e-84	304.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
MMD1_k127_2330565_7	289376.THEYE_A1837	2.99e-66	233.0	COG0127@1|root,COG0127@2|Bacteria,3J0ST@40117|Nitrospirae	40117|Nitrospirae	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
MMD1_k127_2330565_2	289376.THEYE_A1836	1.106e-96	320.0	COG0563@1|root,COG0563@2|Bacteria,3J0K3@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMD1_k127_2330565_1	880072.Desac_0738	1.866e-182	579.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,42NAI@68525|delta/epsilon subdivisions,2WJYY@28221|Deltaproteobacteria,2MR3M@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.1.25,2.7.7.4	ko:K00958,ko:K13811	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
MMD1_k127_2330565_5	194439.CT0864	2.352e-70	240.0	COG1146@1|root,COG1146@2|Bacteria,1FEDS@1090|Chlorobi	1090|Chlorobi	C	Adenosine-5'-phosphosulfate reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_9
MMD1_k127_2330565_0	289376.THEYE_A1832	6.023e-228	711.0	COG1053@1|root,COG1053@2|Bacteria,3J0YZ@40117|Nitrospirae	40117|Nitrospirae	C	FAD binding domain	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
MMD1_k127_2341770_6	1123371.ATXH01000001_gene1241	2.917e-131	425.0	COG0730@1|root,COG0730@2|Bacteria,2GI6P@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_2341770_18	1123371.ATXH01000001_gene1240	1.793e-47	186.0	2AFUA@1|root,315WQ@2|Bacteria,2GIA0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Putative transmembrane protein (Alph_Pro_TM)	-	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
MMD1_k127_2341770_24	797114.C475_17673	2.232e-27	124.0	COG0589@1|root,arCOG00449@2157|Archaea,2XVPB@28890|Euryarchaeota,23SHQ@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_2341770_27	644281.MFS40622_0301	2.821e-08	61.0	COG0589@1|root,arCOG02053@2157|Archaea,2XX8Y@28890|Euryarchaeota,23QW3@183939|Methanococci	183939|Methanococci	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_2341770_8	637390.AFOH01000110_gene2869	1.481e-122	416.0	2BH64@1|root,33QKM@2|Bacteria,1NR5U@1224|Proteobacteria,1T8UM@1236|Gammaproteobacteria,2NDG0@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE_N
MMD1_k127_2341770_13	637389.Acaty_c2637	1.806e-103	351.0	COG3071@1|root,COG3071@2|Bacteria,1NX21@1224|Proteobacteria,1TE02@1236|Gammaproteobacteria,2NDG3@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE_N
MMD1_k127_2341770_10	1121438.JNJA01000001_gene2585	3.951e-119	398.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,439Y6@68525|delta/epsilon subdivisions,2X1VE@28221|Deltaproteobacteria,2M9ND@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMD1_k127_2341770_20	596151.DesfrDRAFT_3641	2.977e-43	160.0	COG2204@1|root,COG2204@2|Bacteria,1PZDN@1224|Proteobacteria,435WZ@68525|delta/epsilon subdivisions,2X0DD@28221|Deltaproteobacteria,2MBWS@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_2341770_2	667014.Thein_2065	1.157e-179	593.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GHHP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
MMD1_k127_2341770_22	926562.Oweho_3009	1.152e-39	160.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMD1_k127_2341770_23	1232410.KI421414_gene2927	2.568e-30	130.0	COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,42V8E@68525|delta/epsilon subdivisions,2WS8I@28221|Deltaproteobacteria,43SQU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
MMD1_k127_2341770_1	644282.Deba_0117	7.959e-189	599.0	COG0126@1|root,COG0126@2|Bacteria,1R5QA@1224|Proteobacteria,42MED@68525|delta/epsilon subdivisions,2WMKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Phosphoglycerate kinase	-	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
MMD1_k127_2341770_11	56780.SYN_02721	1.372e-117	395.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2MSKQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,HD_5
MMD1_k127_2341770_25	264732.Moth_1278	1.703e-12	69.0	COG1826@1|root,COG1826@2|Bacteria,1VFP2@1239|Firmicutes,24V8A@186801|Clostridia,42HG9@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMD1_k127_2341770_16	1121430.JMLG01000006_gene1765	6.668e-65	226.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,261GH@186807|Peptococcaceae	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
MMD1_k127_2341770_7	338963.Pcar_1615	9.006e-126	409.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43S21@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMD1_k127_2341770_3	330214.NIDE2540	4.703e-171	546.0	COG0044@1|root,COG0044@2|Bacteria,3J0D7@40117|Nitrospirae	40117|Nitrospirae	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
MMD1_k127_2341770_21	909663.KI867150_gene2122	1.86e-42	167.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Metallophos
MMD1_k127_2341770_4	404380.Gbem_1898	5.376e-168	535.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43TE7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	TIGRFAM carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
MMD1_k127_2341770_12	243231.GSU1274	5.143e-107	355.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,43SFJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
MMD1_k127_2341770_0	316067.Geob_3271	0.0	1539.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,43TR2@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
MMD1_k127_2341770_19	289376.THEYE_A0541	2.963e-47	182.0	COG0782@1|root,COG0782@2|Bacteria,3J0NA@40117|Nitrospirae	40117|Nitrospirae	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
MMD1_k127_2341770_17	1167006.UWK_00235	1.055e-53	199.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,2MKD4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
MMD1_k127_2341770_9	760568.Desku_1289	2.006e-122	400.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,260Y3@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
MMD1_k127_2341770_14	443144.GM21_0267	3.414e-102	357.0	COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42TFH@68525|delta/epsilon subdivisions,2WPEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMD1_k127_2341770_5	338963.Pcar_2718	5.401e-138	452.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_2341770_15	316067.Geob_0764	1.479e-72	253.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2351291_1	443144.GM21_0216	9.265e-44	163.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,43TYR@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
MMD1_k127_2351291_2	56780.SYN_00726	2.226e-28	120.0	COG0589@1|root,COG0589@2|Bacteria,1NY54@1224|Proteobacteria,430VB@68525|delta/epsilon subdivisions,2WW2X@28221|Deltaproteobacteria,2MSCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_2351291_0	472759.Nhal_1302	0.0	1014.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,1RMA7@1236|Gammaproteobacteria,1WWVT@135613|Chromatiales	135613|Chromatiales	E	PFAM peptidase M1, membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
MMD1_k127_2352100_8	1167006.UWK_01157	2.816e-29	117.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria,2MI12@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hynA	-	1.12.2.1,1.12.5.1,1.12.99.6	ko:K00437,ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
MMD1_k127_2352100_0	1121403.AUCV01000054_gene2604	1.677e-232	728.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria,2MI12@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hynA	-	1.12.2.1,1.12.5.1,1.12.99.6	ko:K00437,ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
MMD1_k127_2352100_7	289376.THEYE_A1941	9.693e-43	163.0	COG0680@1|root,COG0680@2|Bacteria,3J16R@40117|Nitrospirae	40117|Nitrospirae	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
MMD1_k127_2352100_10	1121866.AUGK01000002_gene1653	0.0001997	51.0	COG0298@1|root,COG0298@2|Bacteria	2|Bacteria	O	carbon dioxide binding	hypC	-	-	ko:K04653,ko:K04654	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS11355	HupF_HypC
MMD1_k127_2352100_9	883156.HMPREF9282_00714	4.197e-21	100.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,4H581@909932|Negativicutes	909932|Negativicutes	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
MMD1_k127_2352100_4	1123376.AUIU01000001_gene791	1.281e-91	305.0	COG0378@1|root,COG0378@2|Bacteria,3J128@40117|Nitrospirae	40117|Nitrospirae	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
MMD1_k127_2352100_1	1123376.AUIU01000012_gene1341	1.245e-231	746.0	COG0068@1|root,COG0068@2|Bacteria,3J0WS@40117|Nitrospirae	40117|Nitrospirae	O	Telomere recombination	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
MMD1_k127_2352100_2	289376.THEYE_A1019	2.088e-129	422.0	COG0409@1|root,COG0409@2|Bacteria,3J0W7@40117|Nitrospirae	40117|Nitrospirae	O	Hydrogenase formation hypA family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
MMD1_k127_2352100_3	357808.RoseRS_0975	4.547e-112	371.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi,376G0@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
MMD1_k127_2352100_6	765913.ThidrDRAFT_0521	1.086e-72	261.0	COG3907@1|root,COG3907@2|Bacteria,1QV68@1224|Proteobacteria,1TIBV@1236|Gammaproteobacteria,1WW5N@135613|Chromatiales	135613|Chromatiales	S	PFAM Phosphatidic acid phosphatase type 2 haloperoxidase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
MMD1_k127_2352100_5	1265505.ATUG01000003_gene316	1.548e-83	283.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,42PC9@68525|delta/epsilon subdivisions,2WKA4@28221|Deltaproteobacteria,2MJ22@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
MMD1_k127_2353969_2	666686.B1NLA3E_11105	1.942e-18	95.0	COG0697@1|root,COG0697@2|Bacteria,1UAMA@1239|Firmicutes,4HBUB@91061|Bacilli,1ZQ38@1386|Bacillus	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD1_k127_2353969_0	1499967.BAYZ01000190_gene3862	8.211e-208	652.0	COG0499@1|root,COG0499@2|Bacteria,2NNQE@2323|unclassified Bacteria	2|Bacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMD1_k127_2353969_1	1000565.METUNv1_02979	1.315e-151	480.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,2KVI2@206389|Rhodocyclales	206389|Rhodocyclales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
MMD1_k127_2356579_12	397948.Cmaq_0517	9.944e-06	49.0	COG0801@1|root,arCOG07203@2157|Archaea	2157|Archaea	H	Dihydroneopterin aldolase	-	-	-	-	-	-	-	-	-	-	-	-	FolB,HPPK
MMD1_k127_2356579_4	1499967.BAYZ01000145_gene6204	1.423e-72	249.0	COG0302@1|root,COG0302@2|Bacteria,2NPAT@2323|unclassified Bacteria	2|Bacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
MMD1_k127_2356579_5	1267533.KB906733_gene3082	1.628e-65	229.0	COG5483@1|root,COG5483@2|Bacteria,3Y4X5@57723|Acidobacteria,2JJPI@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
MMD1_k127_2356579_9	1232410.KI421421_gene3837	4.804e-20	96.0	COG5512@1|root,COG5512@2|Bacteria,1N24G@1224|Proteobacteria,42TXW@68525|delta/epsilon subdivisions,2WQ15@28221|Deltaproteobacteria,43SMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
MMD1_k127_2356579_1	1123376.AUIU01000015_gene483	5.568e-145	466.0	COG1085@1|root,COG1085@2|Bacteria,3J0ER@40117|Nitrospirae	40117|Nitrospirae	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
MMD1_k127_2356579_0	1499967.BAYZ01000014_gene6353	9.509e-170	545.0	COG0297@1|root,COG0297@2|Bacteria,2NP1F@2323|unclassified Bacteria	2|Bacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
MMD1_k127_2356579_2	1499967.BAYZ01000014_gene6352	1.001e-139	473.0	COG0642@1|root,COG2205@2|Bacteria	1499967.BAYZ01000014_gene6352|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2356579_7	706587.Desti_1647	2.71e-31	130.0	COG0745@1|root,COG0745@2|Bacteria,1N3R6@1224|Proteobacteria,42TU3@68525|delta/epsilon subdivisions,2WQ9W@28221|Deltaproteobacteria,2MSJP@213462|Syntrophobacterales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_2356579_3	292459.STH2818	3.786e-73	263.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
MMD1_k127_2356579_11	485915.Dret_0191	1.001e-17	90.0	COG1633@1|root,COG1633@2|Bacteria,1NFZ6@1224|Proteobacteria,42WJS@68525|delta/epsilon subdivisions,2WRFE@28221|Deltaproteobacteria,2MGKI@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMD1_k127_2356579_6	215803.DB30_4809	9.038e-57	206.0	COG0726@1|root,COG0726@2|Bacteria,1R8KN@1224|Proteobacteria,43A76@68525|delta/epsilon subdivisions,2X9W7@28221|Deltaproteobacteria,2YYMU@29|Myxococcales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
MMD1_k127_2356579_8	484770.UFO1_0506	1.654e-24	105.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4H37S@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
MMD1_k127_2361737_3	883.DvMF_0023	1.946e-08	57.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,2M82V@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
MMD1_k127_2361737_1	1232410.KI421413_gene824	3.029e-56	211.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43RXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
MMD1_k127_2361737_2	1232410.KI421413_gene825	4.74e-56	213.0	COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria,43TAA@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
MMD1_k127_2361737_0	289376.THEYE_A0382	3.143e-182	577.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,3J0AI@40117|Nitrospirae	40117|Nitrospirae	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
MMD1_k127_2389372_7	574087.Acear_1666	2.512e-32	133.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,3WATS@53433|Halanaerobiales	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
MMD1_k127_2389372_8	930946.AEOP01000019_gene939	3.296e-32	127.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,4AXVF@81850|Leuconostocaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
MMD1_k127_2389372_0	999423.HMPREF9161_00091	3.548e-167	539.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H29G@909932|Negativicutes	909932|Negativicutes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
MMD1_k127_2389372_6	1121920.AUAU01000025_gene2340	1.919e-47	179.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMD1_k127_2389372_5	404380.Gbem_2356	5.205e-77	265.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,42NRF@68525|delta/epsilon subdivisions,2WJZ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMD1_k127_2389372_3	316067.Geob_0764	1.829e-80	278.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2389372_1	316067.Geob_0763	5.695e-113	370.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2389372_2	1304880.JAGB01000004_gene1476	6.82e-88	301.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
MMD1_k127_2389372_4	1123072.AUDH01000008_gene275	2.943e-78	277.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JP9V@204441|Rhodospirillales	204441|Rhodospirillales	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMD1_k127_2389372_9	1123252.ATZF01000003_gene3380	1.105e-17	84.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,27B97@186824|Thermoactinomycetaceae	91061|Bacilli	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMD1_k127_239641_0	768670.Calni_0315	2.364e-143	463.0	COG0649@1|root,COG0649@2|Bacteria,2GF9Z@200930|Deferribacteres	200930|Deferribacteres	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
MMD1_k127_239641_3	765914.ThisiDRAFT_2605	2.404e-20	97.0	COG0664@1|root,COG0664@2|Bacteria,1RD80@1224|Proteobacteria,1S4Q2@1236|Gammaproteobacteria,1WY7A@135613|Chromatiales	135613|Chromatiales	T	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
MMD1_k127_239641_2	713587.THITH_12970	6.515e-35	143.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMD1_k127_239641_1	648996.Theam_0736	4.796e-85	288.0	COG1894@1|root,COG1894@2|Bacteria,2G3V6@200783|Aquificae	200783|Aquificae	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMD1_k127_2396872_1	374847.Kcr_0115	1.952e-52	192.0	COG1042@1|root,arCOG01338@2157|Archaea	2157|Archaea	C	Acyl-CoA synthetase (NDP forming)	acdB	-	6.2.1.13	ko:K01905,ko:K18594,ko:K22224	ko00010,ko00620,ko00640,ko00720,ko01100,ko01120,map00010,map00620,map00640,map00720,map01100,map01120	-	R00229,R00920,R03157	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
MMD1_k127_2396872_0	880072.Desac_0441	1.868e-115	393.0	COG0515@1|root,COG2199@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,1PEAT@1224|Proteobacteria,4306N@68525|delta/epsilon subdivisions,2WVD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
MMD1_k127_2396872_2	357808.RoseRS_2583	0.0003987	44.0	COG0457@1|root,COG1672@1|root,COG4995@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG4995@2|Bacteria,2GAQF@200795|Chloroflexi,37720@32061|Chloroflexia	32061|Chloroflexia	K	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12
MMD1_k127_2401829_3	1242864.D187_009139	1.407e-69	239.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
MMD1_k127_2401829_1	316067.Geob_0753	1.528e-78	272.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMD1_k127_2401829_2	335543.Sfum_0066	6.052e-74	255.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,42MEH@68525|delta/epsilon subdivisions,2WMSC@28221|Deltaproteobacteria,2MQF0@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
MMD1_k127_2401829_0	289376.THEYE_A1397	1.026e-197	627.0	COG1220@1|root,COG1220@2|Bacteria,3J0XE@40117|Nitrospirae	40117|Nitrospirae	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
MMD1_k127_2401829_4	868864.Dester_0316	1.891e-30	121.0	COG0548@1|root,COG0548@2|Bacteria,2G3SD@200783|Aquificae	200783|Aquificae	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
MMD1_k127_2405760_3	589865.DaAHT2_0550	1.301e-93	316.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MITK@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMD1_k127_2405760_10	1121918.ARWE01000001_gene2718	1.462e-25	110.0	COG2005@1|root,COG2005@2|Bacteria	2|Bacteria	P	Transcriptional regulator	-	-	-	ko:K02019,ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.6.2,3.A.1.6.4	-	-	HTH_1,PBP_like_2
MMD1_k127_2405760_1	289376.THEYE_A2096	7.758e-103	344.0	COG2896@1|root,COG2896@2|Bacteria,3J0PB@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Mob_synth_C,Radical_SAM
MMD1_k127_2405760_6	667014.Thein_0586	6.985e-74	253.0	COG2191@1|root,COG2191@2|Bacteria,2GICJ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE
MMD1_k127_2405760_11	640081.Dsui_0146	6.863e-23	108.0	COG3381@1|root,COG3381@2|Bacteria,1RAXF@1224|Proteobacteria,2VY6I@28216|Betaproteobacteria,2KXH2@206389|Rhodocyclales	206389|Rhodocyclales	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
MMD1_k127_2405760_14	96561.Dole_0195	1.493e-12	78.0	COG2180@1|root,COG2180@2|Bacteria,1NDAU@1224|Proteobacteria	1224|Proteobacteria	C	nitrate reductase molybdenum cofactor assembly chaperone	-	-	-	ko:K17052	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	EB_dh
MMD1_k127_2405760_2	123214.PERMA_0658	7.178e-101	342.0	COG1140@1|root,COG1140@2|Bacteria,2G4XI@200783|Aquificae	200783|Aquificae	C	4Fe-4S dicluster domain	-	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Fer4_11
MMD1_k127_2405760_0	1324957.K933_02681	1.827e-229	742.0	COG5013@1|root,arCOG01497@2157|Archaea,2XTNG@28890|Euryarchaeota,23TXI@183963|Halobacteria	183963|Halobacteria	C	Nitrate reductase alpha subunit	narG	-	-	ko:K17050	-	-	-	-	ko00000,ko02000	5.A.3.8	-	-	Molybdopterin,Molydop_binding
MMD1_k127_2405760_8	335543.Sfum_2815	3.224e-49	182.0	COG4314@1|root,COG4314@2|Bacteria,1RID8@1224|Proteobacteria,42SYX@68525|delta/epsilon subdivisions,2WPEE@28221|Deltaproteobacteria,2MSFE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
MMD1_k127_2405760_5	56780.SYN_01953	6.391e-82	279.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMD1_k127_2405760_9	338963.Pcar_0595	1.741e-34	138.0	COG2165@1|root,COG2165@2|Bacteria,1MZ5I@1224|Proteobacteria,42SYC@68525|delta/epsilon subdivisions,2WP7P@28221|Deltaproteobacteria,43SJF@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretory pathway, pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2405760_4	1047013.AQSP01000122_gene2225	9.837e-89	317.0	COG0642@1|root,COG4585@1|root,COG2205@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	ABC_sub_bind,GAF_2,HAMP,HATPase_c,HisKA_3,PAS,PAS_9,Response_reg
MMD1_k127_2405760_12	1223521.BBJX01000014_gene313	4.512e-21	109.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9PA@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
MMD1_k127_2405760_13	1173024.KI912149_gene5682	1.814e-16	94.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1G2I4@1117|Cyanobacteria,1JH30@1189|Stigonemataceae	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
MMD1_k127_2405760_16	658086.HMPREF0994_03610	4.439e-05	54.0	COG2199@1|root,COG3706@2|Bacteria,1VADD@1239|Firmicutes,25E7Q@186801|Clostridia,27MZ3@186928|unclassified Lachnospiraceae	186801|Clostridia	T	diguanylate cyclase	-	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2,GAF_3,GGDEF
MMD1_k127_2405760_15	1123278.KB893441_gene1914	2.249e-09	68.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,47Q8M@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMD1_k127_2405760_7	589865.DaAHT2_0550	3.375e-71	246.0	COG0303@1|root,COG0303@2|Bacteria,1QUKM@1224|Proteobacteria,42NTF@68525|delta/epsilon subdivisions,2X75Q@28221|Deltaproteobacteria,2MITK@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMD1_k127_2408046_0	1121422.AUMW01000023_gene2748	5.522e-183	586.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,260CN@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMD1_k127_2408046_1	1123376.AUIU01000011_gene973	4.534e-133	441.0	COG0265@1|root,COG0265@2|Bacteria,3J0VW@40117|Nitrospirae	40117|Nitrospirae	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMD1_k127_2408046_2	1162668.LFE_1417	4.429e-100	337.0	COG4956@1|root,COG4956@2|Bacteria,3J0G5@40117|Nitrospirae	40117|Nitrospirae	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
MMD1_k127_2408046_3	278963.ATWD01000002_gene938	1.725e-38	147.0	COG0217@1|root,COG0217@2|Bacteria,3Y2UW@57723|Acidobacteria,2JIJW@204432|Acidobacteriia	204432|Acidobacteriia	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMD1_k127_2409342_4	1232410.KI421412_gene377	1.998e-07	56.0	COG3005@1|root,COG3005@2|Bacteria,1N8UB@1224|Proteobacteria,43EW2@68525|delta/epsilon subdivisions,2X24R@28221|Deltaproteobacteria,43STV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	cbcA	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_2409342_0	289376.THEYE_A1057	6.281e-77	265.0	COG4117@1|root,COG4117@2|Bacteria	2|Bacteria	C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)	ydhU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03620,ko:K08354	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10149	RC02823	ko00000,ko00001,ko02000	5.A.3.5	-	-	Cytochrome_C7,Ni_hydr_CYTB
MMD1_k127_2409342_3	420324.KI912045_gene4610	4.473e-08	61.0	2EFQ8@1|root,339G8@2|Bacteria,1RB9T@1224|Proteobacteria,2U5C9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2409342_1	1163617.SCD_n00425	2.361e-48	178.0	COG0662@1|root,COG0662@2|Bacteria,1RHRM@1224|Proteobacteria,2VTBD@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2409342_2	1167006.UWK_02807	7.308e-25	107.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,2MKN7@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
MMD1_k127_2418158_31	1123376.AUIU01000012_gene1507	1.712e-08	57.0	COG1532@1|root,COG1532@2|Bacteria	2|Bacteria	S	Predicted RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RNA_bind_2
MMD1_k127_2418158_10	1123376.AUIU01000011_gene1122	3.403e-96	328.0	COG0583@1|root,COG1910@1|root,COG0583@2|Bacteria,COG1910@2|Bacteria,3J16P@40117|Nitrospirae	40117|Nitrospirae	K	Transcriptional regulator	-	-	-	ko:K11921,ko:K19338	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
MMD1_k127_2418158_9	671143.DAMO_0319	3.316e-109	384.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria	2|Bacteria	U	Metallo-beta-lactamase superfamily	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
MMD1_k127_2418158_30	443143.GM18_2812	1.53e-10	69.0	2DXYI@1|root,34771@2|Bacteria,1P0DZ@1224|Proteobacteria,431TH@68525|delta/epsilon subdivisions,2WX2S@28221|Deltaproteobacteria,43VCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2418158_6	243231.GSU1805	1.416e-198	632.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,43U7Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMD1_k127_2418158_20	289376.THEYE_A0045	1.087e-38	153.0	COG4856@1|root,COG4856@2|Bacteria,3J1EE@40117|Nitrospirae	40117|Nitrospirae	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
MMD1_k127_2418158_13	1123376.AUIU01000011_gene928	2.945e-85	289.0	COG1624@1|root,COG1624@2|Bacteria,3J0XP@40117|Nitrospirae	40117|Nitrospirae	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
MMD1_k127_2418158_12	574087.Acear_1783	1.192e-90	313.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,3WBAE@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
MMD1_k127_2418158_1	671143.DAMO_1565	6.887e-260	813.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
MMD1_k127_2418158_16	330214.NIDE2738	1.794e-54	198.0	COG0634@1|root,COG0634@2|Bacteria,3J0NZ@40117|Nitrospirae	40117|Nitrospirae	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
MMD1_k127_2418158_11	264732.Moth_0104	1.498e-92	321.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,42F58@68295|Thermoanaerobacterales	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
MMD1_k127_2418158_28	1123376.AUIU01000016_gene307	2.72e-13	78.0	COG1734@1|root,COG1734@2|Bacteria,3J0R1@40117|Nitrospirae	40117|Nitrospirae	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
MMD1_k127_2418158_4	123214.PERMA_0605	8.322e-214	701.0	COG0308@1|root,COG0750@1|root,COG3016@1|root,COG0308@2|Bacteria,COG0750@2|Bacteria,COG3016@2|Bacteria,2G4YW@200783|Aquificae	200783|Aquificae	M	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
MMD1_k127_2418158_29	323259.Mhun_2191	8.668e-11	66.0	arCOG08014@1|root,arCOG08014@2157|Archaea,2Y5ZS@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2418158_7	349161.Dred_1160	8.866e-144	471.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2602V@186807|Peptococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
MMD1_k127_2418158_24	316067.Geob_0435	1.991e-23	111.0	COG0745@1|root,COG0745@2|Bacteria	316067.Geob_0435|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2418158_0	760568.Desku_0441	0.0	1087.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,260HP@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
MMD1_k127_2418158_25	1131269.AQVV01000012_gene2603	5.464e-19	100.0	COG2980@1|root,COG2980@2|Bacteria	2|Bacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
MMD1_k127_2418158_18	243231.GSU2207	7.754e-49	187.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42SNR@68525|delta/epsilon subdivisions,2WP96@28221|Deltaproteobacteria,43TIV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
MMD1_k127_2418158_27	439235.Dalk_1195	3.07e-14	76.0	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria,2MKX3@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
MMD1_k127_2418158_8	1499967.BAYZ01000167_gene6737	3.451e-128	427.0	COG0728@1|root,COG0728@2|Bacteria,2NNX8@2323|unclassified Bacteria	2|Bacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
MMD1_k127_2418158_23	243164.DET1460	1.14e-23	106.0	COG0350@1|root,COG0350@2|Bacteria,2G6TT@200795|Chloroflexi,34DBJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
MMD1_k127_2418158_33	585530.HMPREF0183_0160	0.0001846	44.0	COG0350@1|root,COG0350@2|Bacteria,2IHXW@201174|Actinobacteria,4FA77@85019|Brevibacteriaceae	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
MMD1_k127_2418158_15	177437.HRM2_31220	2e-66	239.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria,2MJKK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD1_k127_2418158_3	671143.DAMO_2848	2.09e-227	713.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2NNX4@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	CBS,IMPDH,NMO
MMD1_k127_2418158_14	330214.NIDE1423	4.579e-84	299.0	COG1187@1|root,COG1187@2|Bacteria,3J0RN@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.21,5.4.99.22	ko:K06178,ko:K06181,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
MMD1_k127_2418158_21	1125863.JAFN01000001_gene1677	2.241e-32	128.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,42V8V@68525|delta/epsilon subdivisions,2WRKG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
MMD1_k127_2418158_26	485918.Cpin_7283	4.171e-17	91.0	2CRK8@1|root,32SP8@2|Bacteria,4NWA3@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4253
MMD1_k127_2418158_19	1267535.KB906767_gene735	1.527e-43	170.0	COG1073@1|root,COG1073@2|Bacteria,3Y5TG@57723|Acidobacteria,2JNP5@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2418158_17	671143.DAMO_1553	1.9e-49	184.0	COG1214@1|root,COG1214@2|Bacteria,2NPK8@2323|unclassified Bacteria	2|Bacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
MMD1_k127_2418158_22	330214.NIDE1679	5.274e-26	114.0	COG0454@1|root,COG0456@2|Bacteria,3J1CI@40117|Nitrospirae	40117|Nitrospirae	K	Acetyltransferase (GNAT) domain	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
MMD1_k127_2418158_5	351160.RCIX1841	1.394e-202	645.0	COG0129@1|root,arCOG04045@2157|Archaea,2XSW2@28890|Euryarchaeota,2N992@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A2069	ILVD_EDD
MMD1_k127_2418158_2	289376.THEYE_A1275	6.208e-230	721.0	COG0028@1|root,COG0028@2|Bacteria,3J0D6@40117|Nitrospirae	40117|Nitrospirae	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
MMD1_k127_2420539_5	330214.NIDE0532	2.159e-40	151.0	COG1691@1|root,COG1691@2|Bacteria	2|Bacteria	C	(AIR) carboxylase	cpmA	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
MMD1_k127_2420539_6	706587.Desti_2960	6.967e-34	134.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,42WQ3@68525|delta/epsilon subdivisions,2WS2E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
MMD1_k127_2420539_1	706587.Desti_4488	5.963e-116	385.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
MMD1_k127_2420539_3	1499967.BAYZ01000037_gene2451	1.17e-46	171.0	COG0614@1|root,COG0614@2|Bacteria,2NRFM@2323|unclassified Bacteria	2|Bacteria	P	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	PDDEXK_3
MMD1_k127_2420539_0	255470.cbdbA1049	5.525e-204	650.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi,34CY9@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
MMD1_k127_2420539_2	1499967.BAYZ01000118_gene3287	7.867e-87	295.0	COG0313@1|root,COG0313@2|Bacteria,2NP98@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
MMD1_k127_2420539_4	203124.Tery_2349	1.882e-42	166.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria	1117|Cyanobacteria	M	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
MMD1_k127_2420539_7	1232410.KI421412_gene435	2.164e-19	89.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42PI3@68525|delta/epsilon subdivisions,2WJN3@28221|Deltaproteobacteria,43TSZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
MMD1_k127_2424480_2	289376.THEYE_A1832	5.469e-67	230.0	COG1053@1|root,COG1053@2|Bacteria,3J0YZ@40117|Nitrospirae	40117|Nitrospirae	C	FAD binding domain	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
MMD1_k127_2424480_1	880072.Desac_0735	1.091e-167	538.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,42NHH@68525|delta/epsilon subdivisions,2WJ6M@28221|Deltaproteobacteria,2MQY4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	qmoA	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,NAD_binding_8,Pyr_redox_2
MMD1_k127_2424480_0	289376.THEYE_A1830	1.216e-313	975.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	qmoB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885,ko:K16886	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
MMD1_k127_2424480_3	747365.Thena_1595	7.608e-46	166.0	COG1150@1|root,COG1150@2|Bacteria,1TRAM@1239|Firmicutes,24CFA@186801|Clostridia,42HT9@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17
MMD1_k127_243271_39	452637.Oter_1467	2.251e-09	59.0	COG2067@1|root,COG2067@2|Bacteria,46U6Z@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
MMD1_k127_243271_18	1121918.ARWE01000001_gene219	4.478e-76	261.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,43S4Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
MMD1_k127_243271_21	56780.SYN_00857	4.287e-62	231.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	CP_0755	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Response_reg
MMD1_k127_243271_4	56780.SYN_00856	4.509e-172	556.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,42MRD@68525|delta/epsilon subdivisions,2X5MW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
MMD1_k127_243271_1	243231.GSU1456	2.989e-296	934.0	COG0457@1|root,COG0457@2|Bacteria,1NU49@1224|Proteobacteria,42YQH@68525|delta/epsilon subdivisions,2WU55@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_243271_23	243231.GSU1457	5.83e-60	223.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria	1224|Proteobacteria	G	polysaccharide deacetylase	pgaB	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016787,GO:0016810,GO:0043170,GO:0043412,GO:0071704,GO:0098732	-	ko:K11931,ko:K21478	ko02026,map02026	-	R03096	RC00010	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
MMD1_k127_243271_8	243231.GSU1458	2.731e-104	357.0	COG0457@1|root,COG0457@2|Bacteria,1NSZ2@1224|Proteobacteria,42Z7H@68525|delta/epsilon subdivisions,2WTRC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_243271_27	1121468.AUBR01000008_gene2058	7.599e-41	162.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia,42GIK@68295|Thermoanaerobacterales	186801|Clostridia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
MMD1_k127_243271_5	370438.PTH_1386	1.553e-131	429.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,2607Y@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
MMD1_k127_243271_7	269799.Gmet_0034	8.751e-106	355.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2WKJY@28221|Deltaproteobacteria,43SDV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
MMD1_k127_243271_40	546414.Deide_09070	2.242e-06	58.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
MMD1_k127_243271_24	1288494.EBAPG3_20620	8.857e-57	203.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria,372T2@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
MMD1_k127_243271_38	338969.Rfer_0253	5.49e-10	65.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria	1224|Proteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_243271_34	1125863.JAFN01000001_gene3499	7.083e-16	89.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM cell wall hydrolase autolysin	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
MMD1_k127_243271_36	96561.Dole_1616	4.144e-13	78.0	COG5401@1|root,COG5401@2|Bacteria,1NA0G@1224|Proteobacteria,42V1V@68525|delta/epsilon subdivisions,2WRCV@28221|Deltaproteobacteria,2MKUK@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
MMD1_k127_243271_11	243231.GSU2923	4.339e-96	321.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,43TAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
MMD1_k127_243271_9	335543.Sfum_1671	6.694e-103	350.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,2MQBB@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Mur ligase, middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
MMD1_k127_243271_15	316067.Geob_1869	1.64e-87	314.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,43TYF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
MMD1_k127_243271_31	404589.Anae109_1180	8.977e-26	111.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
MMD1_k127_243271_22	1232410.KI421413_gene937	6.722e-61	222.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,43SFK@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMD1_k127_243271_30	1379698.RBG1_1C00001G1492	5.997e-27	111.0	COG1278@1|root,COG1278@2|Bacteria,2NPXP@2323|unclassified Bacteria	2|Bacteria	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMD1_k127_243271_35	452637.Oter_1462	1.327e-15	79.0	COG0607@1|root,COG2391@1|root,COG0607@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.1,2.8.1.2	ko:K00406,ko:K01011,ko:K07112	ko00190,ko00270,ko00920,ko01100,ko01120,ko02020,ko04122,map00190,map00270,map00920,map01100,map01120,map02020,map04122	M00156	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	PALP,Rhodanese,Sulf_transp
MMD1_k127_243271_28	452637.Oter_1462	6.553e-29	123.0	COG0607@1|root,COG2391@1|root,COG0607@2|Bacteria,COG2391@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.1,2.8.1.2	ko:K00406,ko:K01011,ko:K07112	ko00190,ko00270,ko00920,ko01100,ko01120,ko02020,ko04122,map00190,map00270,map00920,map01100,map01120,map02020,map04122	M00156	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	PALP,Rhodanese,Sulf_transp
MMD1_k127_243271_20	945713.IALB_1660	1.526e-62	220.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
MMD1_k127_243271_32	1033810.HLPCO_001056	9.404e-24	106.0	COG0640@1|root,COG0640@2|Bacteria,2NQ74@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
MMD1_k127_243271_0	706587.Desti_3053	0.0	1125.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2MQB9@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
MMD1_k127_243271_29	1382356.JQMP01000003_gene2283	5.024e-28	114.0	COG0361@1|root,COG0361@2|Bacteria,2G70W@200795|Chloroflexi,27YKS@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
MMD1_k127_243271_37	1229172.JQFA01000004_gene1338	7.034e-11	70.0	COG5413@1|root,COG5413@2|Bacteria,1G3RC@1117|Cyanobacteria,1H7H9@1150|Oscillatoriales	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2301
MMD1_k127_243271_17	909663.KI867150_gene2931	5.223e-77	267.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2X201@28221|Deltaproteobacteria,2MRTK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
MMD1_k127_243271_12	313624.NSP_44870	2.648e-93	326.0	COG0661@1|root,COG0661@2|Bacteria,1G0X9@1117|Cyanobacteria,1HIPC@1161|Nostocales	1117|Cyanobacteria	S	pfam abc1	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
MMD1_k127_243271_10	1121413.JMKT01000001_gene1765	1.504e-97	334.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,42NI3@68525|delta/epsilon subdivisions,2WJ6P@28221|Deltaproteobacteria,2M856@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
MMD1_k127_243271_2	1123371.ATXH01000007_gene541	5.323e-256	801.0	COG0119@1|root,COG0119@2|Bacteria,2GHCY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,dCache_1
MMD1_k127_243271_14	398767.Glov_3613	1.303e-87	294.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
MMD1_k127_243271_33	1123389.ATXJ01000004_gene1189	2.538e-20	100.0	COG2815@1|root,COG2815@2|Bacteria,1WJKE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PASTA domain	-	-	-	-	-	-	-	-	-	-	-	-	PASTA
MMD1_k127_243271_6	760568.Desku_1315	8.555e-114	382.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,2614J@186807|Peptococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
MMD1_k127_243271_16	880072.Desac_1163	5.868e-79	271.0	COG1852@1|root,COG1852@2|Bacteria,1RAI2@1224|Proteobacteria,42QUD@68525|delta/epsilon subdivisions,2WMQ5@28221|Deltaproteobacteria,2MRCC@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF116	-	-	-	ko:K09729	-	-	-	-	ko00000	-	-	-	DUF116
MMD1_k127_243271_13	1123371.ATXH01000007_gene511	1.677e-92	316.0	COG0223@1|root,COG0223@2|Bacteria,2GGW2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
MMD1_k127_243271_26	1232410.KI421426_gene1408	5.13e-52	189.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria,43SIF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Polypeptide deformylase	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
MMD1_k127_243271_19	290397.Adeh_0651	2.3e-71	273.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
MMD1_k127_243271_25	243231.GSU1836	3.281e-55	195.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,43V1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
MMD1_k127_243271_3	706587.Desti_3607	3.114e-239	746.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2MR6S@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
MMD1_k127_2434840_19	404380.Gbem_3155	6.416e-58	204.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42SH0@68525|delta/epsilon subdivisions,2WPFU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
MMD1_k127_2434840_5	269799.Gmet_2424	4.031e-165	539.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,43STW@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	mcp34H-6	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,CZB,HAMP,MCPsignal,dCache_1
MMD1_k127_2434840_28	443143.GM18_3543	2.768e-31	131.0	2ED7H@1|root,33743@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2434840_9	330214.NIDE1246	1.975e-88	301.0	COG0568@1|root,COG0568@2|Bacteria,3J0E4@40117|Nitrospirae	40117|Nitrospirae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
MMD1_k127_2434840_22	316067.Geob_2164	1.394e-53	203.0	COG0745@1|root,COG0745@2|Bacteria,1NV0N@1224|Proteobacteria,42ZH3@68525|delta/epsilon subdivisions,2WUW0@28221|Deltaproteobacteria,43UQG@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,zinc_ribbon_4
MMD1_k127_2434840_16	1177928.TH2_05813	1.21e-68	240.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,2JRGA@204441|Rhodospirillales	204441|Rhodospirillales	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
MMD1_k127_2434840_14	768710.DesyoDRAFT_1399	3.407e-75	264.0	COG0330@1|root,COG0330@2|Bacteria,1UZJK@1239|Firmicutes,24IK1@186801|Clostridia,261BT@186807|Peptococcaceae	186801|Clostridia	O	PFAM SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
MMD1_k127_2434840_12	1379698.RBG1_1C00001G0230	1.791e-76	276.0	COG2206@1|root,COG2206@2|Bacteria,2NPP4@2323|unclassified Bacteria	2|Bacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMD1_k127_2434840_32	338963.Pcar_1178	7.971e-09	69.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,43TQ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
MMD1_k127_2434840_20	1121423.JONT01000008_gene774	1.127e-57	206.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia,261KE@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
MMD1_k127_2434840_7	1304880.JAGB01000002_gene1752	2.605e-110	362.0	COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia	186801|Clostridia	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
MMD1_k127_2434840_1	404380.Gbem_2329	8.067e-217	683.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
MMD1_k127_2434840_3	316067.Geob_2894	2.215e-178	568.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,43TS7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
MMD1_k127_2434840_27	913865.DOT_5446	2.12e-32	131.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,26201@186807|Peptococcaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
MMD1_k127_2434840_17	398767.Glov_1216	2.621e-68	235.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria,43UNX@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
MMD1_k127_2434840_2	338963.Pcar_1447	4.438e-184	584.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,43S9Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	3,4-dihydroxy-2-butanone 4-phosphate synthase	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
MMD1_k127_2434840_13	1121472.AQWN01000002_gene2312	1.8e-75	258.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,260I1@186807|Peptococcaceae	186801|Clostridia	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
MMD1_k127_2434840_23	429009.Adeg_1196	4.636e-53	193.0	COG2191@1|root,COG2191@2|Bacteria,1UZ0V@1239|Firmicutes,24FX7@186801|Clostridia,42GDF@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM formylmethanofuran dehydrogenase, subunit E region	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
MMD1_k127_2434840_33	1209989.TepiRe1_0616	1.94e-08	59.0	arCOG02716@1|root,3300V@2|Bacteria,1VF7E@1239|Firmicutes,24T1W@186801|Clostridia,42J0A@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2434840_21	269799.Gmet_0494	2.07e-55	197.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,42SID@68525|delta/epsilon subdivisions,2WQ86@28221|Deltaproteobacteria,43SGS@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	nickel-responsive regulator	nikR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
MMD1_k127_2434840_8	1232410.KI421428_gene1008	1.003e-92	325.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,43ADF@68525|delta/epsilon subdivisions,2WMEV@28221|Deltaproteobacteria,43T54@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K02006,ko:K16787	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
MMD1_k127_2434840_18	1232410.KI421428_gene1009	1.865e-66	236.0	COG0619@1|root,COG0619@2|Bacteria,1R2DN@1224|Proteobacteria,43B6A@68525|delta/epsilon subdivisions,2X6JT@28221|Deltaproteobacteria,43S05@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Cobalt transport protein	nikQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
MMD1_k127_2434840_6	1449126.JQKL01000006_gene825	1.184e-110	368.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia	186801|Clostridia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM	cbiM2	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
MMD1_k127_2434840_29	290315.Clim_1059	9.021e-29	125.0	COG1452@1|root,COG1452@2|Bacteria,1FEGW@1090|Chlorobi	1090|Chlorobi	M	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
MMD1_k127_2434840_30	243231.GSU2133	1.385e-20	99.0	2CK97@1|root,349K4@2|Bacteria,1P1DK@1224|Proteobacteria,431PN@68525|delta/epsilon subdivisions,2WWNR@28221|Deltaproteobacteria,43VFR@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2434840_0	269799.Gmet_3509	0.0	1732.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
MMD1_k127_2434840_10	316067.Geob_0857	1.501e-86	302.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42SYF@68525|delta/epsilon subdivisions,2WPNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
MMD1_k127_2434840_26	243231.GSU3398	5.078e-43	174.0	COG1538@1|root,COG1538@2|Bacteria,1R6VY@1224|Proteobacteria,430DM@68525|delta/epsilon subdivisions,2WWMP@28221|Deltaproteobacteria,43VIN@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
MMD1_k127_2434840_24	1095769.CAHF01000006_gene1897	3.862e-52	193.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,2VR7K@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2434840_15	589865.DaAHT2_0820	8.688e-73	255.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,43B10@68525|delta/epsilon subdivisions,2WPB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
MMD1_k127_2434840_11	243231.GSU2724	4.315e-84	297.0	2DVSV@1|root,33X1K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2434840_4	330214.NIDE0399	5.719e-171	554.0	COG0072@1|root,COG0072@2|Bacteria,3J0U7@40117|Nitrospirae	40117|Nitrospirae	J	B3/4 domain	-	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B5
MMD1_k127_2434840_25	330214.NIDE0398	3.495e-46	167.0	COG0016@1|root,COG0016@2|Bacteria,3J0SW@40117|Nitrospirae	40117|Nitrospirae	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
MMD1_k127_2445534_1	1232410.KI421424_gene1681	6.704e-76	268.0	COG1387@1|root,COG1387@2|Bacteria,1R9W5@1224|Proteobacteria,42QNF@68525|delta/epsilon subdivisions,2WMV0@28221|Deltaproteobacteria,43SGE@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	DNA polymerase alpha chain like domain	-	-	-	-	-	-	-	-	-	-	-	-	PHP
MMD1_k127_2445534_0	1123376.AUIU01000013_gene1827	3.33e-126	410.0	COG1242@1|root,COG1242@2|Bacteria	2|Bacteria	K	4 iron, 4 sulfur cluster binding	yhcC	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
MMD1_k127_2481137_1	247490.KSU1_D0473	1.973e-67	232.0	COG0476@1|root,COG0476@2|Bacteria,2IY5K@203682|Planctomycetes	203682|Planctomycetes	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
MMD1_k127_2481137_4	935948.KE386494_gene472	6.818e-24	106.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,42IV1@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Mov34 MPN PAD-1 family protein	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
MMD1_k127_2481137_2	547144.HydHO_0121	1.439e-29	121.0	COG1977@1|root,COG1977@2|Bacteria,2G563@200783|Aquificae	200783|Aquificae	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMD1_k127_2481137_5	289376.THEYE_A1680	3.512e-22	100.0	COG1135@1|root,COG1135@2|Bacteria,3J0VT@40117|Nitrospirae	40117|Nitrospirae	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
MMD1_k127_2481137_0	289376.THEYE_A1682	3.222e-160	514.0	COG3635@1|root,COG3635@2|Bacteria,3J0YA@40117|Nitrospirae	40117|Nitrospirae	G	Metalloenzyme superfamily	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
MMD1_k127_2481137_3	546274.EIKCOROL_01210	8.672e-28	114.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,2KQBF@206351|Neisseriales	206351|Neisseriales	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
MMD1_k127_2511076_1	1121440.AUMA01000009_gene561	6.687e-135	453.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WIXV@28221|Deltaproteobacteria,2MAEK@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
MMD1_k127_2511076_8	309807.SRU_0734	8.576e-05	51.0	2DMHT@1|root,32RN3@2|Bacteria,4NPZK@976|Bacteroidetes	976|Bacteroidetes	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
MMD1_k127_2511076_0	269799.Gmet_2920	4.432e-175	572.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2WJXV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
MMD1_k127_2511076_5	443143.GM18_3817	2.515e-52	193.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,42TQF@68525|delta/epsilon subdivisions,2WQHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
MMD1_k127_2511076_6	443143.GM18_3817	2.782e-42	161.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,42TQF@68525|delta/epsilon subdivisions,2WQHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
MMD1_k127_2511076_4	269799.Gmet_2922	7.749e-82	283.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,43AJV@68525|delta/epsilon subdivisions,2X601@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
MMD1_k127_2511076_7	443144.GM21_3713	1.27e-38	150.0	COG0759@1|root,COG0759@2|Bacteria,1QA6X@1224|Proteobacteria,42VEQ@68525|delta/epsilon subdivisions,2WR96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Haemolytic	-	-	-	-	-	-	-	-	-	-	-	-	Haemolytic
MMD1_k127_2511076_3	443144.GM21_3712	3.76e-99	332.0	COG1729@1|root,COG1729@2|Bacteria,1RGD4@1224|Proteobacteria,42S9U@68525|delta/epsilon subdivisions,2WP0U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,YfiO
MMD1_k127_2511076_2	96561.Dole_1195	3.759e-109	361.0	COG1462@1|root,COG1462@2|Bacteria,1QRM1@1224|Proteobacteria,43A0T@68525|delta/epsilon subdivisions,2X2Q5@28221|Deltaproteobacteria,2MMD7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
MMD1_k127_2534069_3	1131269.AQVV01000016_gene1868	1.352e-27	117.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	2.7.7.80,2.8.1.11,3.13.1.6	ko:K21140,ko:K21147	ko04122,map04122	-	R07459,R07461,R11524	RC00043,RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,Rhodanese,ThiF
MMD1_k127_2534069_0	525904.Tter_1314	1.154e-102	342.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD1_k127_2534069_4	521011.Mpal_1138	7.053e-18	95.0	COG0425@1|root,arCOG02062@2157|Archaea	2157|Archaea	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
MMD1_k127_2534069_1	521011.Mpal_1139	4.801e-78	272.0	COG2221@1|root,arCOG02059@2157|Archaea,2Y7JC@28890|Euryarchaeota,2NAWH@224756|Methanomicrobia	2157|Archaea	C	Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein	-	-	1.5.99.15,1.6.5.3,1.8.4.10,1.8.4.8	ko:K00335,ko:K00390,ko:K18853	ko00190,ko00790,ko00920,ko01100,ko01120,map00190,map00790,map00920,map01100,map01120	M00144,M00176	R02021,R10802,R11945	RC00007,RC00061,RC01584,RC02862	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,NIR_SIR,NIR_SIR_ferr,PAPS_reduct,SLBB
MMD1_k127_2583596_0	335543.Sfum_2814	6.498e-144	464.0	COG0577@1|root,COG0577@2|Bacteria,1P00G@1224|Proteobacteria,42P0D@68525|delta/epsilon subdivisions,2X7MP@28221|Deltaproteobacteria,2MR14@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
MMD1_k127_2583596_1	335543.Sfum_2817	1.316e-95	317.0	COG1136@1|root,COG1136@2|Bacteria,1PFRW@1224|Proteobacteria,42P38@68525|delta/epsilon subdivisions,2WMS9@28221|Deltaproteobacteria,2MRIW@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_2583596_2	398767.Glov_1470	2.514e-63	224.0	28K4S@1|root,2Z9TM@2|Bacteria,1N4AQ@1224|Proteobacteria,42PSN@68525|delta/epsilon subdivisions,2WNF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_258918_3	234267.Acid_4507	1.056e-215	676.0	COG0366@1|root,COG0366@2|Bacteria,3Y2P1@57723|Acidobacteria	57723|Acidobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
MMD1_k127_258918_4	1380355.JNIJ01000023_gene2439	1.251e-165	530.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,2TVAP@28211|Alphaproteobacteria,3JRAG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
MMD1_k127_258918_12	247490.KSU1_C0711	3.387e-37	143.0	COG2827@1|root,COG2827@2|Bacteria,2J3VU@203682|Planctomycetes	203682|Planctomycetes	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
MMD1_k127_258918_9	1419583.V466_02345	7.616e-64	226.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
MMD1_k127_258918_10	1217718.ALOU01000042_gene227	2.626e-41	164.0	2E3FB@1|root,32YE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_258918_1	1123242.JH636434_gene3586	0.0	1020.0	COG1523@1|root,COG1523@2|Bacteria,2IXJM@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
MMD1_k127_258918_2	381666.H16_B2544	3.933e-261	828.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,1KBZ2@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Surface antigen	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
MMD1_k127_258918_8	1304885.AUEY01000092_gene3645	4.096e-76	260.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,42MSW@68525|delta/epsilon subdivisions,2WNY3@28221|Deltaproteobacteria,2MJ39@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
MMD1_k127_258918_7	56780.SYN_02948	5.103e-122	406.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MR8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMD1_k127_258918_0	1121405.dsmv_1541	0.0	1572.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MI2Z@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Hydrophobe Amphiphile Efflux-1 (HAE1) Family	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
MMD1_k127_258918_5	196367.JNFG01000037_gene7588	7.631e-157	512.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,1K1DV@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
MMD1_k127_258918_15	572477.Alvin_0298	1.271e-06	57.0	2ATWF@1|root,31JFP@2|Bacteria,1RK55@1224|Proteobacteria,1S6Q1@1236|Gammaproteobacteria,1WYHR@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_258918_6	644281.MFS40622_0177	1.877e-131	441.0	COG5427@1|root,arCOG00563@2157|Archaea,2Y2Q0@28890|Euryarchaeota,23RIP@183939|Methanococci	183939|Methanococci	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_258918_14	439235.Dalk_2449	2.759e-22	112.0	COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,42XJQ@68525|delta/epsilon subdivisions,2WSMN@28221|Deltaproteobacteria,2MP2F@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_258918_11	574087.Acear_2187	1.141e-37	150.0	COG2121@1|root,COG2121@2|Bacteria,1V6M7@1239|Firmicutes,24KY0@186801|Clostridia,3WAQ4@53433|Halanaerobiales	186801|Clostridia	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
MMD1_k127_258918_13	243231.GSU0568	4.72e-23	104.0	2AFDJ@1|root,315DD@2|Bacteria,1PVF9@1224|Proteobacteria,436DH@68525|delta/epsilon subdivisions,2XA0V@28221|Deltaproteobacteria,43VKE@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2614387_0	1232410.KI421412_gene339	1.007e-67	235.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42QBD@68525|delta/epsilon subdivisions,2WM4P@28221|Deltaproteobacteria,43T7G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
MMD1_k127_2614387_2	1121403.AUCV01000048_gene1063	1.304e-52	189.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria	1224|Proteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
MMD1_k127_2614387_1	1210884.HG799465_gene11339	1.656e-56	204.0	COG0262@1|root,COG0262@2|Bacteria,2J1IB@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMD1_k127_2614387_4	479435.Kfla_1149	1.793e-07	59.0	COG3832@1|root,COG3832@2|Bacteria,2HAK8@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMD1_k127_2614387_3	880072.Desac_0400	1.643e-18	85.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2WKFT@28221|Deltaproteobacteria,2MQ5J@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
MMD1_k127_2622637_1	289376.THEYE_A0933	1.558e-119	389.0	COG0329@1|root,COG0329@2|Bacteria,3J0CF@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
MMD1_k127_2622637_2	56780.SYN_02162	1.777e-101	338.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2MREE@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
MMD1_k127_2622637_4	1232410.KI421415_gene3019	6.53e-49	184.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,42QRZ@68525|delta/epsilon subdivisions,2WMZS@28221|Deltaproteobacteria,43SGM@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
MMD1_k127_2622637_3	880072.Desac_2491	1.053e-93	314.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,42NS5@68525|delta/epsilon subdivisions,2WNQ5@28221|Deltaproteobacteria,2MQFJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
MMD1_k127_2622637_0	1033743.CAES01000013_gene2479	1.408e-184	585.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli,26QSS@186822|Paenibacillaceae	91061|Bacilli	E	Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD1_k127_2633599_11	644282.Deba_1366	7.618e-108	354.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMD1_k127_2633599_16	97138.C820_00531	1.511e-70	254.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
MMD1_k127_2633599_1	404380.Gbem_0904	8.595e-218	692.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
MMD1_k127_2633599_0	671143.DAMO_2469	2.279e-225	711.0	COG0442@1|root,COG0442@2|Bacteria,2NNNH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
MMD1_k127_2633599_4	269799.Gmet_1353	6.745e-157	502.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria,43T8H@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
MMD1_k127_2633599_12	1499967.BAYZ01000078_gene992	2.736e-104	353.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
MMD1_k127_2633599_5	330214.NIDE1511	9.968e-141	457.0	COG0743@1|root,COG0743@2|Bacteria,3J0B0@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
MMD1_k127_2633599_18	671143.DAMO_0675	1.485e-52	195.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
MMD1_k127_2633599_15	1089553.Tph_c11200	2.454e-79	276.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,42F7X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
MMD1_k127_2633599_21	644282.Deba_0421	3.721e-20	106.0	COG5386@1|root,COG5386@2|Bacteria,1QWPV@1224|Proteobacteria,43BUN@68525|delta/epsilon subdivisions,2X75R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
MMD1_k127_2633599_2	880073.Calab_2422	6.38e-199	643.0	COG1449@1|root,COG1449@2|Bacteria,2NQNB@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
MMD1_k127_2633599_20	1296416.JACB01000004_gene1133	1.86e-51	188.0	COG1988@1|root,COG1988@2|Bacteria,4NPMW@976|Bacteroidetes,1I2P2@117743|Flavobacteriia,2YIQT@290174|Aquimarina	976|Bacteroidetes	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
MMD1_k127_2633599_7	1123393.KB891327_gene502	1.189e-135	432.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2VHF9@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMD1_k127_2633599_19	1278073.MYSTI_02032	3.549e-52	190.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1099	AAA_28,Thymidylate_kin
MMD1_k127_2633599_23	671143.DAMO_2368	2.348e-08	63.0	COG3678@1|root,COG3678@2|Bacteria,2NRWA@2323|unclassified Bacteria	2|Bacteria	NPTU	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
MMD1_k127_2633599_17	760568.Desku_2229	7.831e-67	235.0	COG0842@1|root,COG0842@2|Bacteria,1TSWD@1239|Firmicutes,24DHH@186801|Clostridia,261EX@186807|Peptococcaceae	186801|Clostridia	V	PFAM ABC-2 type transporter	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
MMD1_k127_2633599_13	2325.TKV_c16560	1.064e-91	310.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,42FQ5@68295|Thermoanaerobacterales	186801|Clostridia	V	pfam abc	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
MMD1_k127_2633599_3	330214.NIDE1223	4.291e-166	535.0	COG2204@1|root,COG2204@2|Bacteria,3J0C2@40117|Nitrospirae	40117|Nitrospirae	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_2633599_10	880073.Calab_1785	6.966e-123	404.0	COG0709@1|root,COG1104@1|root,COG0709@2|Bacteria,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	selD	-	2.7.9.3,2.8.1.7	ko:K01008,ko:K04487	ko00450,ko00730,ko01100,ko04122,map00450,map00730,map01100,map04122	-	R03595,R07460,R11528,R11529	RC00002,RC01789,RC02313,RC02878	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	AIRS,AIRS_C,Aminotran_5
MMD1_k127_2633599_9	264732.Moth_1706	5.442e-123	406.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,42F5Y@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD1_k127_2633599_8	1123376.AUIU01000011_gene829	4.927e-130	424.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorA	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1307	PFOR_II,POR_N
MMD1_k127_2633599_22	635013.TherJR_1679	1.36e-16	81.0	COG1146@1|root,COG1146@2|Bacteria,1VETY@1239|Firmicutes,25E51@186801|Clostridia,2630V@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
MMD1_k127_2633599_6	269799.Gmet_0942	6.861e-136	458.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,43TM9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
MMD1_k127_2633599_24	1227266.HMPREF1551_02667	0.0001376	51.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia,1EQ2Q@1016|Capnocytophaga	976|Bacteroidetes	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
MMD1_k127_2633599_14	247490.KSU1_C0729	4.302e-88	300.0	COG0616@1|root,COG0616@2|Bacteria,2IYKF@203682|Planctomycetes	203682|Planctomycetes	OU	TIGRFAM signal peptide peptidase SppA, 36K type	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
MMD1_k127_2654061_15	926561.KB900620_gene2911	1.413e-91	316.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
MMD1_k127_2654061_29	1487921.DP68_16100	4.668e-47	178.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia,36DTE@31979|Clostridiaceae	186801|Clostridia	S	Peptidase C26	yvdE	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
MMD1_k127_2654061_11	401526.TcarDRAFT_1041	1.07e-122	401.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H278@909932|Negativicutes	909932|Negativicutes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
MMD1_k127_2654061_4	56780.SYN_02155	1.253e-153	497.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2MQ76@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
MMD1_k127_2654061_18	264732.Moth_1516	1.266e-84	289.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,42FHP@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMD1_k127_2654061_26	1122223.KB890696_gene415	2.03e-56	202.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
MMD1_k127_2654061_43	1005048.CFU_2785	1.112e-16	85.0	2BGVF@1|root,33DVW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2654061_20	443143.GM18_0216	1.431e-73	256.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
MMD1_k127_2654061_37	1463926.JOCA01000029_gene2963	1.072e-27	123.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria	201174|Actinobacteria	E	hydrolases or acyltransferases alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
MMD1_k127_2654061_42	768670.Calni_0644	2.409e-17	86.0	2DRRJ@1|root,33CRQ@2|Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2654061_46	868864.Dester_0706	4.796e-11	67.0	2DRRJ@1|root,33CRQ@2|Bacteria,2G525@200783|Aquificae	200783|Aquificae	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2654061_41	768670.Calni_0644	2.966e-20	94.0	2DRRJ@1|root,33CRQ@2|Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2654061_40	1382304.JNIL01000001_gene2352	3.481e-21	104.0	COG3634@1|root,COG3634@2|Bacteria,1V40Z@1239|Firmicutes,4HIDC@91061|Bacilli,279JI@186823|Alicyclobacillaceae	91061|Bacilli	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
MMD1_k127_2654061_5	56780.SYN_01240	6.109e-140	451.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,2MQ4H@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
MMD1_k127_2654061_36	667014.Thein_0167	2.21e-32	131.0	COG1371@1|root,COG1371@2|Bacteria,2GHUY@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
MMD1_k127_2654061_1	667014.Thein_0246	6.356e-212	667.0	COG1690@1|root,COG1690@2|Bacteria,2GH7Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
MMD1_k127_2654061_16	909663.KI867150_gene2915	8.595e-89	302.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria,2MSKN@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMD1_k127_2654061_9	269799.Gmet_3463	7.459e-130	421.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
MMD1_k127_2654061_7	269799.Gmet_3462	1.687e-135	437.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
MMD1_k127_2654061_6	269799.Gmet_3461	6.389e-138	448.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
MMD1_k127_2654061_3	269799.Gmet_3460	7.87e-158	506.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
MMD1_k127_2654061_23	404589.Anae109_2759	2.929e-65	231.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,42WEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	cytochrome c	norC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
MMD1_k127_2654061_2	443144.GM21_3034	4.643e-197	622.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Cytochrome c oxidase, subunit I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
MMD1_k127_2654061_32	269799.Gmet_0156	5.008e-39	150.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,42U37@68525|delta/epsilon subdivisions,2WQ9M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
MMD1_k127_2654061_39	1121403.AUCV01000078_gene4202	1.092e-22	98.0	COG1141@1|root,COG1141@2|Bacteria,1NFMM@1224|Proteobacteria,42WKK@68525|delta/epsilon subdivisions,2WRFD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Divergent 4Fe-4S mono-cluster	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
MMD1_k127_2654061_33	1123248.KB893326_gene1431	1.405e-36	143.0	2B5RU@1|root,31YMF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
MMD1_k127_2654061_14	289376.THEYE_A1244	8.08e-93	314.0	COG3431@1|root,COG3431@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Protoglobin,PsiE
MMD1_k127_2654061_38	439235.Dalk_3566	1.472e-27	121.0	COG3448@1|root,COG3448@2|Bacteria,1Q1A8@1224|Proteobacteria,42SIQ@68525|delta/epsilon subdivisions,2WPF0@28221|Deltaproteobacteria,2MKBJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMD1_k127_2654061_21	1121403.AUCV01000060_gene3725	1.222e-68	237.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,42RSQ@68525|delta/epsilon subdivisions,2WNED@28221|Deltaproteobacteria,2MJRX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM HPP family	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	HPP
MMD1_k127_2654061_27	123214.PERMA_0133	2.941e-53	190.0	COG0450@1|root,COG0450@2|Bacteria,2G3ZJ@200783|Aquificae	200783|Aquificae	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
MMD1_k127_2654061_45	1121459.AQXE01000005_gene1572	9.27e-15	76.0	COG0450@1|root,COG0450@2|Bacteria,1MYZG@1224|Proteobacteria,42SNG@68525|delta/epsilon subdivisions,2WP3M@28221|Deltaproteobacteria,2M9GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
MMD1_k127_2654061_0	269799.Gmet_0294	1.773e-246	767.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,43TBA@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
MMD1_k127_2654061_24	269799.Gmet_0295	5.543e-63	222.0	COG3005@1|root,COG3005@2|Bacteria,1RI0B@1224|Proteobacteria,42T5J@68525|delta/epsilon subdivisions,2WNR2@28221|Deltaproteobacteria,43UWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
MMD1_k127_2654061_44	748449.Halha_1228	1.413e-15	80.0	COG1917@1|root,COG1917@2|Bacteria,1VCNE@1239|Firmicutes,24PWZ@186801|Clostridia,3WAU9@53433|Halanaerobiales	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD1_k127_2654061_35	768671.ThimaDRAFT_0814	1.01e-32	139.0	COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria,1RZ0Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
MMD1_k127_2654061_13	316067.Geob_0830	4.916e-102	341.0	2C2QQ@1|root,32RAW@2|Bacteria,1NSUD@1224|Proteobacteria,42YHI@68525|delta/epsilon subdivisions,2WUH7@28221|Deltaproteobacteria,43TPF@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	omcX	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2654061_17	443143.GM18_0298	2.089e-87	299.0	COG1276@1|root,COG4892@1|root,COG1276@2|Bacteria,COG4892@2|Bacteria,1N3DP@1224|Proteobacteria,42U1X@68525|delta/epsilon subdivisions,2WQFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Cytochrome b5	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cyt-b5
MMD1_k127_2654061_25	1278309.KB907099_gene2766	1.713e-61	220.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria,1SRHG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2654061_30	402881.Plav_1072	1.742e-43	162.0	COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	RNA signal recognition particle 4.5S RNA	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
MMD1_k127_2654061_28	316067.Geob_1837	1.696e-47	172.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WQFH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
MMD1_k127_2654061_31	316067.Geob_1836	3.382e-39	147.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42VG7@68525|delta/epsilon subdivisions,2WP7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
MMD1_k127_2654061_47	765913.ThidrDRAFT_1486	1.937e-08	59.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
MMD1_k127_2654061_22	237368.SCABRO_02048	7.062e-66	235.0	COG4974@1|root,COG4974@2|Bacteria,2IZG8@203682|Planctomycetes	203682|Planctomycetes	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
MMD1_k127_2654061_10	1538295.JY96_19505	3.681e-124	412.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,2VHXU@28216|Betaproteobacteria,1KJTB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	norB	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
MMD1_k127_2654061_34	264462.Bd2601	2.653e-35	143.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,42WEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	cytochrome c	norC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
MMD1_k127_2654061_19	443143.GM18_3974	5.404e-75	260.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43TXA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
MMD1_k127_2654061_8	1232410.KI421412_gene411	6.689e-135	443.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
MMD1_k127_2654061_12	1125863.JAFN01000001_gene1122	3.73e-115	379.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
MMD1_k127_2661357_14	443143.GM18_0173	2.946e-26	109.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMD1_k127_2661357_8	289376.THEYE_A1917	9.166e-46	179.0	COG0664@1|root,COG0664@2|Bacteria,3J182@40117|Nitrospirae	40117|Nitrospirae	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
MMD1_k127_2661357_1	1123376.AUIU01000013_gene1737	4.896e-210	662.0	COG1350@1|root,COG1350@2|Bacteria,3J1FC@40117|Nitrospirae	40117|Nitrospirae	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD1_k127_2661357_12	1123368.AUIS01000030_gene1253	5.553e-34	134.0	COG1522@1|root,COG1522@2|Bacteria,1NC1H@1224|Proteobacteria,1SE9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
MMD1_k127_2661357_7	1123376.AUIU01000011_gene844	6.066e-52	198.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
MMD1_k127_2661357_5	243231.GSU1613	3.908e-84	289.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,43TKZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	endonuclease III	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
MMD1_k127_2661357_11	1172185.KB911513_gene4635	5.515e-36	159.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4G0TI@85025|Nocardiaceae	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
MMD1_k127_2661357_15	443143.GM18_2606	9.316e-20	106.0	COG1629@1|root,COG2165@1|root,COG2165@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	pilV	GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840	-	ko:K02014,ko:K02456,ko:K02457,ko:K02458,ko:K10926,ko:K10930,ko:K10931	ko03070,ko05110,ko05111,map03070,map05110,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.14,3.A.15	-	-	FecR,N_methyl,Shufflon_N,TPR_16,TPR_8,TcpA
MMD1_k127_2661357_6	443143.GM18_3305	1.494e-52	189.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,42T10@68525|delta/epsilon subdivisions,2WPNN@28221|Deltaproteobacteria,43SPG@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,NUDIX_4
MMD1_k127_2661357_10	443143.GM18_3402	1.005e-38	148.0	COG1917@1|root,COG1917@2|Bacteria,1RHSW@1224|Proteobacteria,42TSH@68525|delta/epsilon subdivisions,2WQ63@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD1_k127_2661357_0	296591.Bpro_4149	0.0	1029.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,4AAXQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
MMD1_k127_2661357_3	349124.Hhal_1902	4.929e-146	487.0	COG2176@1|root,COG5000@1|root,COG2176@2|Bacteria,COG5000@2|Bacteria,1QUVW@1224|Proteobacteria,1RV0N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	PAS_4,PAS_9,RNase_T
MMD1_k127_2661357_9	765914.ThisiDRAFT_2103	4.491e-43	161.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1S571@1236|Gammaproteobacteria,1WYBC@135613|Chromatiales	135613|Chromatiales	KT	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_2661357_2	289376.THEYE_A0033	1.375e-159	527.0	COG2905@1|root,COG2905@2|Bacteria,3J0UW@40117|Nitrospirae	40117|Nitrospirae	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
MMD1_k127_2661357_13	497964.CfE428DRAFT_2347	4.243e-29	128.0	COG4587@1|root,COG4587@2|Bacteria,46VAG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
MMD1_k127_2661357_16	326427.Cagg_3098	4.661e-17	94.0	COG3694@1|root,COG3694@2|Bacteria,2G90J@200795|Chloroflexi,377JE@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
MMD1_k127_2661357_4	658086.HMPREF0994_01265	1.146e-107	359.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_2661357_18	1123376.AUIU01000013_gene1705	1.389e-12	76.0	COG3814@1|root,COG3814@2|Bacteria	2|Bacteria	S	Stringent starvation protein B	MA20_02250	-	-	ko:K09985	-	-	-	-	ko00000	-	-	-	SspB
MMD1_k127_2661357_20	345341.KUTG_04140	6.047e-07	52.0	2DTR4@1|root,33MCB@2|Bacteria,2HAJT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2671061_7	317025.Tcr_0235	6.343e-13	79.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1S5X2@1236|Gammaproteobacteria,462MH@72273|Thiotrichales	72273|Thiotrichales	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2671061_6	398767.Glov_3032	1.31e-44	166.0	COG4315@1|root,COG4315@2|Bacteria,1MZC6@1224|Proteobacteria,4324Y@68525|delta/epsilon subdivisions,2WY5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
MMD1_k127_2671061_0	290397.Adeh_2245	1.616e-230	723.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,2YTUB@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMD1_k127_2671061_1	1125863.JAFN01000001_gene1061	2.085e-82	283.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42MSC@68525|delta/epsilon subdivisions,2WJAH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
MMD1_k127_2671061_4	1125863.JAFN01000001_gene1331	1.095e-72	253.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42YQS@68525|delta/epsilon subdivisions,2WUCI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMD1_k127_2671061_5	696281.Desru_0489	5.627e-71	254.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,24EJ5@186801|Clostridia,260XN@186807|Peptococcaceae	186801|Clostridia	U	PFAM Branched-chain amino acid transport system permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMD1_k127_2671061_3	243231.GSU2006	2.473e-77	268.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMD1_k127_2671061_2	335543.Sfum_0314	4.982e-82	288.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2MRX0@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMD1_k127_2707623_2	234267.Acid_4205	3.329e-58	212.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
MMD1_k127_2707623_3	289376.THEYE_A1305	7.818e-48	175.0	COG1651@1|root,COG1651@2|Bacteria,3J19Z@40117|Nitrospirae	40117|Nitrospirae	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2707623_0	289376.THEYE_A1303	4.913e-138	447.0	COG1858@1|root,COG1858@2|Bacteria,3J0GH@40117|Nitrospirae	40117|Nitrospirae	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
MMD1_k127_2707623_8	443144.GM21_3003	1.488e-15	88.0	COG4972@1|root,COG4972@2|Bacteria,1NUYA@1224|Proteobacteria,42ZJI@68525|delta/epsilon subdivisions,2WV3A@28221|Deltaproteobacteria,43UN3@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pilus assembly protein	pulM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
MMD1_k127_2707623_10	404380.Gbem_1281	1.078e-06	59.0	COG3166@1|root,COG3166@2|Bacteria,1Q5NW@1224|Proteobacteria,431IV@68525|delta/epsilon subdivisions,2WWZG@28221|Deltaproteobacteria,43VK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	PFAM Fimbrial assembly family protein	pulN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
MMD1_k127_2707623_9	1232410.KI421421_gene3653	1.533e-11	72.0	2DXN2@1|root,345N1@2|Bacteria,1Q1PJ@1224|Proteobacteria,4319I@68525|delta/epsilon subdivisions,2WWAH@28221|Deltaproteobacteria,43VEM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pilus assembly protein, PilO	pulO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
MMD1_k127_2707623_1	243231.GSU1778	5.637e-136	464.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,42NBT@68525|delta/epsilon subdivisions,2WKAW@28221|Deltaproteobacteria,43SD0@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	type II and III secretion system protein	pulQ	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,Secretin,Secretin_N
MMD1_k127_2707623_5	338966.Ppro_2414	7.059e-39	150.0	COG2165@1|root,COG2165@2|Bacteria,1RGZZ@1224|Proteobacteria,4303Z@68525|delta/epsilon subdivisions,2WVCX@28221|Deltaproteobacteria,43V07@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Prokaryotic N-terminal methylation motif	pulG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
MMD1_k127_2707623_6	443143.GM18_1145	4.162e-36	141.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria	1224|Proteobacteria	U	type II secretion system protein G	oxpG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
MMD1_k127_2707623_4	1387312.BAUS01000010_gene46	2.477e-43	165.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,2KKZ9@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
MMD1_k127_2707623_7	667014.Thein_1336	5.169e-31	130.0	COG1207@1|root,COG1207@2|Bacteria,2GI7A@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	-
MMD1_k127_271341_0	1173027.Mic7113_2719	3.363e-30	128.0	COG1443@1|root,COG1443@2|Bacteria	2|Bacteria	I	isopentenyl-diphosphate delta-isomerase activity	M1-740	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMD1_k127_271341_1	404589.Anae109_1807	2.92e-24	114.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48,Peptidase_M56
MMD1_k127_2725818_1	269799.Gmet_1429	5.071e-29	123.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,42TQE@68525|delta/epsilon subdivisions,2WQIC@28221|Deltaproteobacteria,43V95@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein Slp family	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
MMD1_k127_2725818_2	1121396.KB892990_gene4505	6.362e-26	118.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,42TQE@68525|delta/epsilon subdivisions,2WQIC@28221|Deltaproteobacteria,2MM2W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein Slp family	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
MMD1_k127_2725818_0	880072.Desac_0525	9.848e-30	126.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,42TQE@68525|delta/epsilon subdivisions,2WQIC@28221|Deltaproteobacteria,2MSI1@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein Slp family	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
MMD1_k127_276363_3	879212.DespoDRAFT_00442	1.325e-19	90.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,2MJCE@213118|Desulfobacterales	28221|Deltaproteobacteria	D	PFAM ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
MMD1_k127_276363_0	555079.Toce_1701	4.824e-124	406.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,42ET8@68295|Thermoanaerobacterales	186801|Clostridia	G	Transketolase, central region	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMD1_k127_276363_1	289376.THEYE_A1486	3.118e-108	359.0	COG3959@1|root,COG3959@2|Bacteria,3J1FM@40117|Nitrospirae	40117|Nitrospirae	G	Dehydrogenase E1 component	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
MMD1_k127_276363_2	1232410.KI421428_gene1050	1.156e-22	106.0	2E2XW@1|root,32XYS@2|Bacteria,1N3ID@1224|Proteobacteria,42UFM@68525|delta/epsilon subdivisions,2WQKF@28221|Deltaproteobacteria,43SQ0@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2769997_0	1232410.KI421415_gene3124	3.83e-156	515.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS domain	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
MMD1_k127_2769997_5	1345697.M493_10570	1.398e-19	94.0	COG0607@1|root,COG0607@2|Bacteria,1VB3C@1239|Firmicutes,4HKWP@91061|Bacilli,1WGEJ@129337|Geobacillus	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMD1_k127_2769997_2	439481.Aboo_0474	1.593e-35	143.0	COG1059@1|root,arCOG04357@2157|Archaea,2XWSZ@28890|Euryarchaeota,3F2WU@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)	ogg	-	4.2.99.18	ko:K03653	-	-	-	-	ko00000,ko01000	-	-	-	-
MMD1_k127_2769997_3	331678.Cphamn1_1908	1.936e-32	130.0	2DNS7@1|root,32YWC@2|Bacteria	2|Bacteria	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMD1_k127_2769997_6	401053.AciPR4_3594	2.014e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,3Y77J@57723|Acidobacteria,2JM29@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMD1_k127_2769997_1	318996.AXAZ01000014_gene2855	7.356e-36	145.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TRW5@28211|Alphaproteobacteria,3JR0X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Sel1,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
MMD1_k127_2769997_4	243231.GSU2913	1.6e-30	132.0	COG3303@1|root,COG3303@2|Bacteria,1NEPE@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	omcP	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_2771191_2	373903.Hore_01680	2.432e-105	355.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3WADU@53433|Halanaerobiales	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
MMD1_k127_2771191_5	909663.KI867150_gene2116	2.091e-79	273.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,2MQXR@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
MMD1_k127_2771191_3	1379698.RBG1_1C00001G0979	8.864e-95	317.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
MMD1_k127_2771191_4	56780.SYN_00409	3.735e-88	308.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2WKQH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
MMD1_k127_2771191_1	309799.DICTH_1516	9.637e-118	387.0	COG1210@1|root,COG1210@2|Bacteria	2|Bacteria	M	Utp--glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
MMD1_k127_2771191_0	338966.Ppro_2604	5.697e-280	877.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,43T3K@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMD1_k127_2804053_3	945713.IALB_2488	5.2e-28	118.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
MMD1_k127_2804053_0	945713.IALB_0296	2.948e-166	547.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
MMD1_k127_2804053_2	1232410.KI421421_gene3834	9.398e-82	290.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria,43SZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
MMD1_k127_2804053_1	1232410.KI421421_gene3835	3.619e-82	288.0	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WIKV@28221|Deltaproteobacteria,43W41@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
MMD1_k127_2804053_5	671065.MetMK1DRAFT_00010490	7.626e-08	59.0	COG5466@1|root,arCOG05278@2157|Archaea	2157|Archaea	S	small metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
MMD1_k127_2804053_4	861299.J421_2541	2.379e-21	98.0	COG4166@1|root,COG4166@2|Bacteria,1ZSMX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMD1_k127_2810098_0	1379698.RBG1_1C00001G0186	1.739e-270	848.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.3.13,2.7.9.1	ko:K01006,ko:K22424	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMD1_k127_2810098_2	1232410.KI421418_gene2188	2.527e-192	622.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,43S34@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
MMD1_k127_2810098_3	639282.DEFDS_0639	1.688e-151	483.0	COG0752@1|root,COG0752@2|Bacteria,2GEZ4@200930|Deferribacteres	200930|Deferribacteres	J	Glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
MMD1_k127_2810098_5	644282.Deba_0514	6.364e-31	128.0	COG0607@1|root,COG0607@2|Bacteria,1Q8VH@1224|Proteobacteria,42UJ3@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMD1_k127_2810098_1	289376.THEYE_A1002	5.95e-215	689.0	COG1449@1|root,COG1449@2|Bacteria,3J0AQ@40117|Nitrospirae	40117|Nitrospirae	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
MMD1_k127_2810098_6	290397.Adeh_1575	6.541e-08	59.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K12065,ko:K13052	-	-	-	-	ko00000,ko02044,ko03036	3.A.7.11.1	-	-	DivIC
MMD1_k127_2810098_4	671143.DAMO_1183	2.252e-47	176.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	DUF86,NTP_transf_2
MMD1_k127_2814214_0	671143.DAMO_2529	2.252e-63	233.0	COG4942@1|root,COG4942@2|Bacteria,2NPDY@2323|unclassified Bacteria	2|Bacteria	D	Peptidase family M23	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
MMD1_k127_2814214_2	269799.Gmet_1855	8.343e-52	196.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria,43T0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
MMD1_k127_2814214_1	1144275.COCOR_06241	4.1e-63	222.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,2YV0E@29|Myxococcales	28221|Deltaproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
MMD1_k127_2864644_0	589865.DaAHT2_0436	2.615e-101	345.0	COG0577@1|root,COG0577@2|Bacteria,1R5BD@1224|Proteobacteria	1224|Proteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD1_k127_2864644_2	589865.DaAHT2_0437	1.043e-63	238.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,4308T@68525|delta/epsilon subdivisions,2WKJ3@28221|Deltaproteobacteria,2MIDE@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter related	lolD-2	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_2864644_3	378806.STAUR_1589	1.544e-10	71.0	COG0664@1|root,COG0664@2|Bacteria,1QZHV@1224|Proteobacteria,43D55@68525|delta/epsilon subdivisions,2X62I@28221|Deltaproteobacteria,2Z38A@29|Myxococcales	28221|Deltaproteobacteria	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2869552_3	596151.DesfrDRAFT_0910	3.809e-31	128.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria,2MCFG@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
MMD1_k127_2869552_1	589865.DaAHT2_1167	3.284e-56	209.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria,2MJIK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
MMD1_k127_2869552_2	555079.Toce_1070	2.057e-42	160.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,42GJ8@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
MMD1_k127_2869552_0	656519.Halsa_1365	6.3e-87	294.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3WB3E@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
MMD1_k127_2878899_0	330214.NIDE3889	6.246e-145	473.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
MMD1_k127_2878899_1	330214.NIDE3890	9.779e-40	152.0	COG0723@1|root,COG0723@2|Bacteria,3J0TT@40117|Nitrospirae	40117|Nitrospirae	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
MMD1_k127_2936225_5	338966.Ppro_1580	2.864e-50	183.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,43TAT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
MMD1_k127_2936225_9	404589.Anae109_1476	7.453e-31	137.0	COG0784@1|root,COG0784@2|Bacteria,1QYG7@1224|Proteobacteria,43E8C@68525|delta/epsilon subdivisions,2X7NA@28221|Deltaproteobacteria,2Z11B@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_2936225_13	1121335.Clst_2108	1.373e-06	57.0	COG0835@1|root,COG0835@2|Bacteria,1V5WY@1239|Firmicutes,24SZ7@186801|Clostridia	186801|Clostridia	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
MMD1_k127_2936225_12	1121289.JHVL01000029_gene461	1.142e-07	59.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia,36ITK@31979|Clostridiaceae	186801|Clostridia	NT	Chemotaxis protein cheW	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
MMD1_k127_2936225_1	717231.Flexsi_0109	4.941e-139	476.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,2GEP8@200930|Deferribacteres	200930|Deferribacteres	T	two-component system, chemotaxis family, sensor kinase CheA with response regulator domain	-	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
MMD1_k127_2936225_2	1499967.BAYZ01000004_gene4926	1.131e-108	375.0	COG0840@1|root,COG0840@2|Bacteria,2NQVC@2323|unclassified Bacteria	2|Bacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	HAMP,MCPsignal
MMD1_k127_2936225_11	1499967.BAYZ01000004_gene4925	1.591e-17	89.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheR,CheW
MMD1_k127_2936225_8	768670.Calni_0653	1.662e-42	159.0	COG0745@1|root,COG0745@2|Bacteria,2GFWK@200930|Deferribacteres	200930|Deferribacteres	T	Twitching motility two-component system response regulator PilH	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
MMD1_k127_2936225_4	1121918.ARWE01000001_gene1429	4.601e-56	213.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
MMD1_k127_2936225_7	156889.Mmc1_1007	4.799e-50	183.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2U864@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
MMD1_k127_2936225_3	398767.Glov_1309	4.634e-69	244.0	COG0642@1|root,COG2205@2|Bacteria,1RK1D@1224|Proteobacteria,42R91@68525|delta/epsilon subdivisions,2WUS5@28221|Deltaproteobacteria,43UMQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMD1_k127_2936225_10	289376.THEYE_A1270	4.322e-26	119.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
MMD1_k127_2936225_0	903818.KI912269_gene335	2.643e-180	572.0	COG0538@1|root,COG0538@2|Bacteria	2|Bacteria	C	isocitrate dehydrogenase activity	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMD1_k127_2936225_6	443143.GM18_0447	4.452e-50	186.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,43UXD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
MMD1_k127_2951693_2	401526.TcarDRAFT_1542	4.562e-157	501.0	COG2221@1|root,COG2221@2|Bacteria,1TZD2@1239|Firmicutes	1239|Firmicutes	C	TIGRFAM sulfite reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
MMD1_k127_2951693_3	880072.Desac_1620	1.085e-153	501.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MQYU@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
MMD1_k127_2951693_16	1121430.JMLG01000002_gene1279	7.426e-14	77.0	COG1413@1|root,COG1413@2|Bacteria,1V19F@1239|Firmicutes,24EN9@186801|Clostridia	186801|Clostridia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_EZ
MMD1_k127_2951693_8	156889.Mmc1_0048	4.466e-49	177.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2U9K5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
MMD1_k127_2951693_14	589865.DaAHT2_1668	2.31e-18	85.0	COG1036@1|root,COG1036@2|Bacteria,1QW15@1224|Proteobacteria,43BR4@68525|delta/epsilon subdivisions,2X721@28221|Deltaproteobacteria,2MPIY@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
MMD1_k127_2951693_19	2423.NA23_0201010	0.0001267	49.0	COG2168@1|root,COG2168@2|Bacteria,2GDEY@200918|Thermotogae	200918|Thermotogae	P	sulfur relay protein TusB DsrH	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
MMD1_k127_2951693_17	309799.DICTH_0385	1.578e-11	70.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	tusD	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234	-	ko:K06039,ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
MMD1_k127_2951693_11	1487923.DP73_20900	1.576e-34	143.0	2CDHP@1|root,32RXU@2|Bacteria,1VQ7W@1239|Firmicutes,251NF@186801|Clostridia,265N8@186807|Peptococcaceae	186801|Clostridia	S	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
MMD1_k127_2951693_4	1487923.DP73_20905	4.392e-130	423.0	COG2181@1|root,COG2181@2|Bacteria,1UYRK@1239|Firmicutes,24FM8@186801|Clostridia,266ZT@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitrate reductase gamma subunit	hmeC	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
MMD1_k127_2951693_0	138119.DSY0313	2.08e-300	927.0	COG0247@1|root,COG0247@2|Bacteria,1TSC1@1239|Firmicutes,24B10@186801|Clostridia,260AF@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	hmeD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
MMD1_k127_2951693_10	1123376.AUIU01000015_gene472	1.731e-39	152.0	arCOG10385@1|root,32SEM@2|Bacteria	2|Bacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2951693_5	1123376.AUIU01000015_gene473	3.503e-91	307.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
MMD1_k127_2951693_1	138119.DSY0316	4.525e-173	550.0	COG5557@1|root,COG5557@2|Bacteria,1UYGM@1239|Firmicutes,24EQA@186801|Clostridia,263KI@186807|Peptococcaceae	186801|Clostridia	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
MMD1_k127_2951693_9	693661.Arcve_1601	7.344e-46	174.0	COG3547@1|root,arCOG03585@2157|Archaea,2XWFH@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
MMD1_k127_2951693_12	216596.RL1973	4.946e-25	116.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,2VF65@28211|Alphaproteobacteria,4BBA2@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Transposase for insertion sequence element	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
MMD1_k127_2951693_18	696281.Desru_1415	1.412e-09	61.0	COG1943@1|root,COG1943@2|Bacteria,1V6R5@1239|Firmicutes,24NQE@186801|Clostridia,266XA@186807|Peptococcaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
MMD1_k127_2951693_6	289376.THEYE_A1058	1.573e-75	275.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB,Paired_CXXCH_1
MMD1_k127_2951693_7	289376.THEYE_A1057	7.382e-69	243.0	COG4117@1|root,COG4117@2|Bacteria	2|Bacteria	C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)	ydhU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03620,ko:K08354	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10149	RC02823	ko00000,ko00001,ko02000	5.A.3.5	-	-	Cytochrome_C7,Ni_hydr_CYTB
MMD1_k127_2960776_9	706587.Desti_4753	1.51e-26	111.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK-2	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMD1_k127_2960776_8	1173022.Cri9333_0059	3.851e-36	143.0	COG0614@1|root,COG0614@2|Bacteria,1G73G@1117|Cyanobacteria,1HFHX@1150|Oscillatoriales	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
MMD1_k127_2960776_5	323261.Noc_1119	3.641e-61	215.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,1S65T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2280,iAF1260.b2280,iAPECO1_1312.APECO1_4285,iB21_1397.B21_02165,iBWG_1329.BWG_2054,iE2348C_1286.E2348C_2420,iEC042_1314.EC042_2521,iEC55989_1330.EC55989_2524,iECABU_c1320.ECABU_c26120,iECBD_1354.ECBD_1381,iECB_1328.ECB_02205,iECDH10B_1368.ECDH10B_2442,iECDH1ME8569_1439.ECDH1ME8569_2217,iECD_1391.ECD_02205,iECED1_1282.ECED1_2744,iECH74115_1262.ECH74115_3419,iECIAI1_1343.ECIAI1_2354,iECIAI39_1322.ECIAI39_2427,iECNA114_1301.ECNA114_2370,iECO103_1326.ECO103_2744,iECO111_1330.ECO111_3028,iECO26_1355.ECO26_3268,iECOK1_1307.ECOK1_2513,iECP_1309.ECP_2319,iECS88_1305.ECS88_2427,iECSE_1348.ECSE_2537,iECSF_1327.ECSF_2157,iECSP_1301.ECSP_3154,iECUMN_1333.ECUMN_2619,iECW_1372.ECW_m2468,iECs_1301.ECs3164,iEKO11_1354.EKO11_1487,iETEC_1333.ETEC_2415,iEcDH1_1363.EcDH1_1377,iEcE24377_1341.EcE24377A_2573,iEcHS_1320.EcHS_A2429,iEcSMS35_1347.EcSMS35_2434,iEcolC_1368.EcolC_1372,iJO1366.b2280,iJR904.b2280,iLF82_1304.LF82_1547,iNRG857_1313.NRG857_11545,iSBO_1134.SBO_2313,iSDY_1059.SDY_2476,iSFV_1184.SFV_2347,iSF_1195.SF2356,iSFxv_1172.SFxv_2600,iSSON_1240.SSON_2337,iS_1188.S2491,iSbBS512_1146.SbBS512_E2656,iUMN146_1321.UM146_05415,iUMNK88_1353.UMNK88_2830,iUTI89_1310.UTI89_C2560,iWFL_1372.ECW_m2468,iY75_1357.Y75_RS11955,iZ_1308.Z3539,ic_1306.c2821	Oxidored_q3
MMD1_k127_2960776_4	105559.Nwat_1908	5.481e-86	288.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,1RN32@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	e_coli_core.b2281,iAF1260.b2281,iAPECO1_1312.APECO1_4284,iB21_1397.B21_02166,iBWG_1329.BWG_2055,iE2348C_1286.E2348C_2421,iEC042_1314.EC042_2522,iEC55989_1330.EC55989_2525,iECABU_c1320.ECABU_c26130,iECBD_1354.ECBD_1380,iECB_1328.ECB_02206,iECDH10B_1368.ECDH10B_2443,iECDH1ME8569_1439.ECDH1ME8569_2218,iECD_1391.ECD_02206,iECED1_1282.ECED1_2745,iECH74115_1262.ECH74115_3420,iECIAI1_1343.ECIAI1_2355,iECIAI39_1322.ECIAI39_2428,iECNA114_1301.ECNA114_2371,iECO103_1326.ECO103_2745,iECO111_1330.ECO111_3029,iECO26_1355.ECO26_3269,iECOK1_1307.ECOK1_2514,iECP_1309.ECP_2320,iECS88_1305.ECS88_2428,iECSE_1348.ECSE_2538,iECSF_1327.ECSF_2158,iECSP_1301.ECSP_3155,iECUMN_1333.ECUMN_2620,iECW_1372.ECW_m2469,iECs_1301.ECs3165,iEKO11_1354.EKO11_1486,iETEC_1333.ETEC_2416,iEcDH1_1363.EcDH1_1376,iEcE24377_1341.EcE24377A_2574,iEcHS_1320.EcHS_A2430,iEcSMS35_1347.EcSMS35_2435,iEcolC_1368.EcolC_1371,iG2583_1286.G2583_2818,iJO1366.b2281,iJR904.b2281,iLF82_1304.LF82_1546,iNRG857_1313.NRG857_11550,iPC815.YPO2548,iSBO_1134.SBO_2314,iSFV_1184.SFV_2348,iSF_1195.SF2357,iSFxv_1172.SFxv_2601,iS_1188.S2492,iSbBS512_1146.SbBS512_E2657,iUMN146_1321.UM146_05410,iUMNK88_1353.UMNK88_2831,iUTI89_1310.UTI89_C2561,iWFL_1372.ECW_m2469,iY75_1357.Y75_RS11960,iZ_1308.Z3540,ic_1306.c2822	Fer4
MMD1_k127_2960776_2	1267535.KB906767_gene61	9.629e-148	475.0	COG1005@1|root,COG1005@2|Bacteria,3Y3VS@57723|Acidobacteria,2JHQZ@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
MMD1_k127_2960776_0	1266925.JHVX01000004_gene1249	0.0	1098.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,373XN@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
MMD1_k127_2960776_7	933262.AXAM01000026_gene3091	6.997e-38	145.0	COG0614@1|root,COG0614@2|Bacteria,1MZ6W@1224|Proteobacteria,42W2Q@68525|delta/epsilon subdivisions,2WRCB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
MMD1_k127_2960776_1	323848.Nmul_A1017	4.942e-193	610.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,3745P@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
MMD1_k127_2960776_6	1123368.AUIS01000006_gene658	7.836e-51	184.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,2NCTW@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMD1_k127_2960776_3	1266925.JHVX01000004_gene1252	4.85e-139	445.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,3743I@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
MMD1_k127_2962358_5	443143.GM18_1138	1e-26	126.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WTUB@28221|Deltaproteobacteria,43T1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-1	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
MMD1_k127_2962358_1	330214.NIDE2826	2.464e-84	294.0	COG1459@1|root,COG1459@2|Bacteria,3J0HZ@40117|Nitrospirae	40117|Nitrospirae	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
MMD1_k127_2962358_3	521011.Mpal_1408	1.242e-59	212.0	COG0262@1|root,arCOG01490@2157|Archaea,2XYCD@28890|Euryarchaeota	28890|Euryarchaeota	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMD1_k127_2962358_6	483219.LILAB_34370	4.086e-25	107.0	COG4430@1|root,COG4430@2|Bacteria,1NASK@1224|Proteobacteria,43202@68525|delta/epsilon subdivisions,2WX2P@28221|Deltaproteobacteria,2Z2U2@29|Myxococcales	28221|Deltaproteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
MMD1_k127_2962358_0	933262.AXAM01000033_gene1627	4.306e-110	368.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MJGP@213118|Desulfobacterales	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
MMD1_k127_2962358_4	1089553.Tph_c25500	1.671e-54	196.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,1TQH8@1239|Firmicutes,2491Q@186801|Clostridia,42EU7@68295|Thermoanaerobacterales	186801|Clostridia	S	Extradiol ring-cleavage dioxygenase, class III	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
MMD1_k127_2962358_2	335543.Sfum_1586	6.779e-71	248.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2MQBX@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMD1_k127_2965193_2	1200557.JHWV01000002_gene133	7.85e-48	179.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4H4H3@909932|Negativicutes	909932|Negativicutes	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
MMD1_k127_2965193_1	1125863.JAFN01000001_gene2047	5.653e-53	192.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,42SXB@68525|delta/epsilon subdivisions,2WPP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Isochorismatase	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
MMD1_k127_2965193_0	1220534.B655_1300	5.118e-133	428.0	COG1488@1|root,arCOG01481@2157|Archaea,2XU8Y@28890|Euryarchaeota	28890|Euryarchaeota	H	Nicotinic acid phosphoribosyltransferase	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	QRPTase_C,QRPTase_N
MMD1_k127_2967332_5	395493.BegalDRAFT_2496	6.131e-59	209.0	COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,1S6KW@1236|Gammaproteobacteria,462QH@72273|Thiotrichales	72273|Thiotrichales	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
MMD1_k127_2967332_3	1230476.C207_03722	9.396e-92	314.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TYVX@28211|Alphaproteobacteria,3JX48@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
MMD1_k127_2967332_8	420662.Mpe_A0534	2.917e-10	69.0	2EV5S@1|root,33NKJ@2|Bacteria,1NI0N@1224|Proteobacteria,2VYM4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3568)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3568
MMD1_k127_2967332_0	443143.GM18_3980	0.0	1237.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,43T5A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
MMD1_k127_2967332_9	477974.Daud_2196	0.0004188	49.0	COG1413@1|root,COG1413@2|Bacteria,1V19F@1239|Firmicutes,24EN9@186801|Clostridia,263V6@186807|Peptococcaceae	186801|Clostridia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_EZ
MMD1_k127_2967332_1	1232410.KI421424_gene1630	0.0	1047.0	COG1199@1|root,COG1199@2|Bacteria,1MVRJ@1224|Proteobacteria,42NV8@68525|delta/epsilon subdivisions,2WJIW@28221|Deltaproteobacteria,43TMV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DEAD_2	-	-	3.6.4.12	ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2
MMD1_k127_2967332_6	1123376.AUIU01000014_gene586	1.179e-22	105.0	COG2920@1|root,COG2920@2|Bacteria	2|Bacteria	P	part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
MMD1_k127_2967332_4	269799.Gmet_2409	9.898e-72	246.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42SWA@68525|delta/epsilon subdivisions,2WPE1@28221|Deltaproteobacteria,43W0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
MMD1_k127_2967332_2	391625.PPSIR1_00300	1.103e-100	338.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42P72@68525|delta/epsilon subdivisions,2WKRS@28221|Deltaproteobacteria,2YXDE@29|Myxococcales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	gyaR	-	1.1.1.26	ko:K00015,ko:K15893	ko00260,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map01100,map01110,map01120,map01130,map01200	M00532	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMD1_k127_2986255_5	404589.Anae109_3433	1.42e-154	500.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMD1_k127_2986255_4	1121918.ARWE01000001_gene2442	6.883e-165	526.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,43S46@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Rad51	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
MMD1_k127_2986255_19	552811.Dehly_1587	1.807e-37	147.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,34D41@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
MMD1_k127_2986255_7	1379698.RBG1_1C00001G1886	3.816e-113	379.0	COG1058@1|root,COG1058@2|Bacteria,2NP0G@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
MMD1_k127_2986255_20	1123401.JHYQ01000006_gene101	5.557e-35	139.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,46126@72273|Thiotrichales	72273|Thiotrichales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
MMD1_k127_2986255_13	247490.KSU1_C0975	7.268e-81	274.0	2EFCU@1|root,3395Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2986255_9	247490.KSU1_C0965	2.264e-104	352.0	COG0643@1|root,COG0643@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K03320,ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	1.A.11	-	-	Ammonium_transp,CheW,EAL,GGDEF,HATPase_c,Hpt,PilJ
MMD1_k127_2986255_24	177439.DP0753	1.311e-16	87.0	2ARUS@1|root,31H6C@2|Bacteria,1RFAK@1224|Proteobacteria,42SPB@68525|delta/epsilon subdivisions,2WPJK@28221|Deltaproteobacteria,2MKD1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	-	-	-	-	-	-	-	-	-	HSDR_N_2
MMD1_k127_2986255_26	589865.DaAHT2_2176	2.823e-16	86.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MKH2@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
MMD1_k127_2986255_18	706587.Desti_3149	3.299e-38	153.0	COG0613@1|root,COG0613@2|Bacteria,1RF04@1224|Proteobacteria,42RR4@68525|delta/epsilon subdivisions,2WNC8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM PHP domain	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
MMD1_k127_2986255_21	247490.KSU1_D0452	1.046e-30	134.0	COG0859@1|root,COG0859@2|Bacteria,2J4DC@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
MMD1_k127_2986255_23	429009.Adeg_1298	2.986e-20	95.0	COG1504@1|root,COG1504@2|Bacteria,1VQ3G@1239|Firmicutes,24W0D@186801|Clostridia,42IZQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
MMD1_k127_2986255_3	247490.KSU1_D0644	1.245e-166	537.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,2IY5R@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
MMD1_k127_2986255_14	1509405.GV67_06905	3.009e-77	267.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,4B8UC@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter, ATP-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
MMD1_k127_2986255_8	289376.THEYE_A1130	2.335e-105	355.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	-	-	-	-	-	-	-	-	-	TauE
MMD1_k127_2986255_17	1123376.AUIU01000012_gene1389	3.453e-42	160.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_2986255_6	177437.HRM2_12120	5.858e-118	386.0	COG2043@1|root,COG2043@2|Bacteria,1RDAZ@1224|Proteobacteria,42S9A@68525|delta/epsilon subdivisions,2WNG5@28221|Deltaproteobacteria,2MKK4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
MMD1_k127_2986255_0	1340493.JNIF01000003_gene1859	2.689e-195	629.0	COG4122@1|root,COG4122@2|Bacteria,3Y33U@57723|Acidobacteria	57723|Acidobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2986255_28	56780.SYN_03122	8.82e-12	72.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2986255_15	443144.GM21_0249	6.305e-75	258.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,42RS2@68525|delta/epsilon subdivisions,2X9GK@28221|Deltaproteobacteria,43W2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
MMD1_k127_2986255_2	1125863.JAFN01000001_gene1744	1.068e-176	568.0	COG0535@1|root,COG0535@2|Bacteria,1R58E@1224|Proteobacteria,42NSA@68525|delta/epsilon subdivisions,2WJVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
MMD1_k127_2986255_12	316067.Geob_0763	1.687e-90	305.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_2986255_11	429009.Adeg_1141	1.065e-99	343.0	COG3894@1|root,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42F3G@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
MMD1_k127_2986255_27	289376.THEYE_A1391	2.592e-14	76.0	COG4980@1|root,COG4980@2|Bacteria,3J1B3@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
MMD1_k127_2986255_10	153948.NAL212_2064	4.152e-101	344.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2WEJA@28216|Betaproteobacteria,374P7@32003|Nitrosomonadales	28216|Betaproteobacteria	EO	pdz dhr glgf	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M1,Peptidase_M28
MMD1_k127_2986255_22	589865.DaAHT2_0705	2.086e-22	106.0	arCOG05277@1|root,336C4@2|Bacteria,1NZZE@1224|Proteobacteria,43162@68525|delta/epsilon subdivisions,2WWEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2986255_1	1167006.UWK_02855	1.623e-180	601.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N46@68525|delta/epsilon subdivisions,2WJT4@28221|Deltaproteobacteria,2MPMZ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg
MMD1_k127_2986255_16	439235.Dalk_4458	2.647e-44	186.0	COG0784@1|root,COG2198@1|root,COG2202@1|root,COG2204@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BU6@68525|delta/epsilon subdivisions,2X756@28221|Deltaproteobacteria,2MPM5@213118|Desulfobacterales	68525|delta/epsilon subdivisions	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_8,PAS_9,Response_reg
MMD1_k127_2989937_5	357808.RoseRS_4380	8.38e-20	96.0	2EMP9@1|root,33FBQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2989937_1	1232437.KL661963_gene3380	9.373e-107	358.0	COG1148@1|root,COG1148@2|Bacteria,1N26U@1224|Proteobacteria,43BRX@68525|delta/epsilon subdivisions,2WKFG@28221|Deltaproteobacteria,2MJAN@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
MMD1_k127_2989937_2	880073.Calab_0150	5.1e-61	222.0	COG1597@1|root,COG1597@2|Bacteria,2NQYH@2323|unclassified Bacteria	2|Bacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
MMD1_k127_2989937_0	330214.NIDE2574	1.024e-221	699.0	COG0138@1|root,COG0138@2|Bacteria,3J0CV@40117|Nitrospirae	40117|Nitrospirae	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
MMD1_k127_2989937_4	1125863.JAFN01000001_gene359	4.653e-24	110.0	COG0457@1|root,COG0457@2|Bacteria,1N0Q1@1224|Proteobacteria,42TBT@68525|delta/epsilon subdivisions,2WQ96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
MMD1_k127_2989937_6	330214.NIDE0491	4.748e-07	56.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	tmoA	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494	1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1	ko:K00688,ko:K15760,ko:K16157,ko:K16242,ko:K18223,ko:K22353,ko:K22357	ko00361,ko00362,ko00500,ko00623,ko00625,ko00640,ko00680,ko01100,ko01110,ko01120,ko01200,ko01220,ko02026,ko04217,ko04910,ko04922,ko04931,map00361,map00362,map00500,map00623,map00625,map00640,map00680,map01100,map01110,map01120,map01200,map01220,map02026,map04217,map04910,map04922,map04931	M00174,M00538,M00548	R01142,R02111,R02550,R03560,R03562,R03608,R05444,R05666,R10042,R10043,R10702,R11901	RC00046,RC00173,RC00269,RC00490,RC01383,RC03249	ko00000,ko00001,ko00002,ko01000	-	GT35	-	Phenol_Hydrox,YHS
MMD1_k127_2989937_3	706587.Desti_4638	7.899e-30	127.0	COG3034@1|root,COG3034@2|Bacteria,1QTMV@1224|Proteobacteria,42W1K@68525|delta/epsilon subdivisions,2X5QE@28221|Deltaproteobacteria,2MS74@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMD1_k127_2993035_5	1121440.AUMA01000009_gene561	2.401e-146	477.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WIXV@28221|Deltaproteobacteria,2MAEK@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
MMD1_k127_2993035_21	247490.KSU1_C0843	2.624e-47	179.0	COG0631@1|root,COG0631@2|Bacteria,2IZ62@203682|Planctomycetes	203682|Planctomycetes	T	PFAM Protein phosphatase	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
MMD1_k127_2993035_25	1232410.KI421421_gene3537	3.685e-35	145.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,43SZ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Tetratricopeptide repeat	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
MMD1_k127_2993035_17	635013.TherJR_1133	1.557e-53	198.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,2625C@186807|Peptococcaceae	186801|Clostridia	H	TIGRFAM siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
MMD1_k127_2993035_34	401053.AciPR4_0590	3.361e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,3Y6J0@57723|Acidobacteria,2JKHK@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
MMD1_k127_2993035_32	588596.U9UT08	1.452e-08	68.0	COG0484@1|root,KOG0715@2759|Eukaryota,38H0N@33154|Opisthokonta,3NUEY@4751|Fungi	4751|Fungi	O	chaperone	MDJ1	GO:0000002,GO:0001671,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005829,GO:0006457,GO:0006458,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006996,GO:0007005,GO:0008047,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016043,GO:0019538,GO:0019866,GO:0019898,GO:0030163,GO:0030234,GO:0030544,GO:0031072,GO:0031090,GO:0031312,GO:0031314,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032781,GO:0042026,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043462,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051336,GO:0051345,GO:0051603,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0071840,GO:0098772,GO:1901564,GO:1901565,GO:1901575	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMD1_k127_2993035_28	1232410.KI421428_gene1212	1.46e-18	101.0	COG0457@1|root,COG0457@2|Bacteria,1R7XY@1224|Proteobacteria,42NFC@68525|delta/epsilon subdivisions,2WMA4@28221|Deltaproteobacteria,43S9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
MMD1_k127_2993035_3	316067.Geob_1233	5.257e-159	514.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,43TZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
MMD1_k127_2993035_18	720554.Clocl_2765	1.659e-53	198.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
MMD1_k127_2993035_19	1444309.JAQG01000025_gene3808	6.358e-52	189.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,4HGXD@91061|Bacilli,26WZE@186822|Paenibacillaceae	91061|Bacilli	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
MMD1_k127_2993035_1	443144.GM21_1160	6.878e-181	574.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43U6J@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
MMD1_k127_2993035_11	316067.Geob_2673	1.947e-76	258.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,43U1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
MMD1_k127_2993035_15	316067.Geob_2674	1.437e-54	195.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,43UTR@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
MMD1_k127_2993035_2	1232410.KI421421_gene3895	2.64e-176	577.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,43RXS@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
MMD1_k127_2993035_24	649638.Trad_2541	3.076e-42	159.0	COG1764@1|root,COG1764@2|Bacteria,1WJVD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	redox protein regulator of disulfide bond formation	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
MMD1_k127_2993035_16	997296.PB1_09642	5.082e-54	193.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1ZFJ0@1386|Bacillus	91061|Bacilli	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
MMD1_k127_2993035_6	56780.SYN_02346	1.607e-134	433.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	DLH
MMD1_k127_2993035_12	1210908.HSB1_36690	8.343e-69	244.0	COG0300@1|root,arCOG01263@2157|Archaea,2Y7K7@28890|Euryarchaeota,23VXJ@183963|Halobacteria	183963|Halobacteria	I	Belongs to the short-chain dehydrogenases reductases (SDR) family	yqjQ	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
MMD1_k127_2993035_29	713586.KB900536_gene2647	1.436e-16	82.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,1S61Y@1236|Gammaproteobacteria,1WZ34@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0250 family	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
MMD1_k127_2993035_10	290315.Clim_1499	3.767e-78	268.0	COG4912@1|root,COG4912@2|Bacteria,1FDUX@1090|Chlorobi	1090|Chlorobi	L	PFAM DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
MMD1_k127_2993035_20	316067.Geob_1750	1.173e-47	176.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,42UMS@68525|delta/epsilon subdivisions,2WQAV@28221|Deltaproteobacteria,43SQB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
MMD1_k127_2993035_27	1313265.JNIE01000003_gene1132	2.46e-19	94.0	COG0607@1|root,COG0607@2|Bacteria,2G56H@200783|Aquificae	200783|Aquificae	P	Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMD1_k127_2993035_9	671143.DAMO_1931	5.737e-82	289.0	COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD1_k127_2993035_13	330214.NIDE3917	3.666e-56	211.0	COG0845@1|root,COG0845@2|Bacteria,3J13X@40117|Nitrospirae	40117|Nitrospirae	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMD1_k127_2993035_0	329726.AM1_0471	1.269e-315	997.0	COG0841@1|root,COG0841@2|Bacteria,1G21T@1117|Cyanobacteria	1117|Cyanobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMD1_k127_2993035_23	1118054.CAGW01000024_gene348	1.508e-43	169.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4HB73@91061|Bacilli,271SW@186822|Paenibacillaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	M00087	R03026,R04170,R04738,R04740,R04744,R04746	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
MMD1_k127_2993035_31	868864.Dester_1043	5.915e-15	77.0	2DJZI@1|root,307YH@2|Bacteria,2G55Y@200783|Aquificae	200783|Aquificae	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
MMD1_k127_2993035_33	1158318.ATXC01000001_gene73	1.053e-05	49.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
MMD1_k127_2993035_30	110663.KI911558_gene2299	2.667e-15	82.0	COG2127@1|root,COG2127@2|Bacteria,1G6M6@1117|Cyanobacteria,1H0X1@1129|Synechococcus	1117|Cyanobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
MMD1_k127_2993035_4	56780.SYN_00221	2.918e-153	494.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42NJ1@68525|delta/epsilon subdivisions,2WJ5S@28221|Deltaproteobacteria,2MQHY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Putative RNA methylase family UPF0020	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
MMD1_k127_2993035_22	1173264.KI913950_gene4603	4.121e-45	166.0	2DNS7@1|root,32YWC@2|Bacteria,1GPZR@1117|Cyanobacteria,1HG4Q@1150|Oscillatoriales	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMD1_k127_2993035_7	1123376.AUIU01000004_gene1174	2.097e-120	402.0	COG0031@1|root,COG0031@2|Bacteria,3J0HD@40117|Nitrospirae	40117|Nitrospirae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD1_k127_2993035_26	157783.LK03_14035	1.13e-31	128.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,1SCG7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fe-S-cluster oxidoreductase	yeiW	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
MMD1_k127_2993035_14	401526.TcarDRAFT_2679	1.702e-55	202.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H3KV@909932|Negativicutes	909932|Negativicutes	H	PFAM biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
MMD1_k127_2993035_35	338966.Ppro_2157	3.375e-05	50.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_2993035_8	909663.KI867151_gene3063	1.5e-98	330.0	COG0415@1|root,COG0415@2|Bacteria,1RG4D@1224|Proteobacteria,42NWP@68525|delta/epsilon subdivisions,2WJUA@28221|Deltaproteobacteria,2MQYG@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
MMD1_k127_3006840_1	340177.Cag_0946	4.431e-82	276.0	COG4108@1|root,COG4108@2|Bacteria,1FEXE@1090|Chlorobi	1090|Chlorobi	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
MMD1_k127_3006840_4	653733.Selin_2244	5.034e-12	73.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
MMD1_k127_3006840_3	1232410.KI421422_gene2045	2.094e-21	102.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,43SQ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	ATP synthase B/B' CF(0)	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
MMD1_k127_3006840_2	246197.MXAN_7026	1.973e-24	109.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,2YVS8@29|Myxococcales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
MMD1_k127_3006840_0	639282.DEFDS_1888	1.5e-243	760.0	COG0056@1|root,COG0056@2|Bacteria,2GER4@200930|Deferribacteres	200930|Deferribacteres	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
MMD1_k127_3014894_6	547163.BN979_00353	1.609e-14	79.0	COG0664@1|root,COG0664@2|Bacteria,2IF4P@201174|Actinobacteria,237B5@1762|Mycobacteriaceae	201174|Actinobacteria	T	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20
MMD1_k127_3014894_3	247490.KSU1_C1590	3.375e-76	264.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMD1_k127_3014894_1	237368.SCABRO_02228	2.225e-103	353.0	COG0304@1|root,COG0304@2|Bacteria,2J2GF@203682|Planctomycetes	203682|Planctomycetes	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMD1_k127_3014894_5	237368.SCABRO_02230	8.497e-34	134.0	COG0764@1|root,COG0764@2|Bacteria,2J0AE@203682|Planctomycetes	203682|Planctomycetes	I	COG0764 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier	-	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
MMD1_k127_3014894_0	247490.KSU1_C1687	2.843e-138	451.0	COG0304@1|root,COG0304@2|Bacteria,2J1Z9@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMD1_k127_3014894_7	1158318.ATXC01000002_gene1634	1.793e-11	67.0	COG0236@1|root,COG0236@2|Bacteria,2G491@200783|Aquificae	200783|Aquificae	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
MMD1_k127_3014894_4	237368.SCABRO_02227	6.999e-72	260.0	COG1233@1|root,COG1233@2|Bacteria,2IYK4@203682|Planctomycetes	203682|Planctomycetes	C	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMD1_k127_3014894_2	706587.Desti_3270	1.181e-90	325.0	COG2202@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
MMD1_k127_3014894_8	1265505.ATUG01000001_gene3827	6.137e-07	57.0	2DP65@1|root,330PS@2|Bacteria,1NCIJ@1224|Proteobacteria,42W40@68525|delta/epsilon subdivisions,2WS36@28221|Deltaproteobacteria,2MM5V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
MMD1_k127_3019134_2	269799.Gmet_3035	1.87e-155	507.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43TW5@69541|Desulfuromonadales	28221|Deltaproteobacteria	JKL	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C,R3H
MMD1_k127_3019134_0	867903.ThesuDRAFT_01312	4.216e-192	616.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WCXQ@538999|Clostridiales incertae sedis	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMD1_k127_3019134_6	357804.Ping_2605	4.893e-135	442.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RNGU@1236|Gammaproteobacteria,2QHYZ@267894|Psychromonadaceae	1236|Gammaproteobacteria	I	Thiolase, C-terminal domain	pcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
MMD1_k127_3019134_1	506534.Rhein_0964	4.516e-176	575.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,1RMZ8@1236|Gammaproteobacteria,1WX97@135613|Chromatiales	135613|Chromatiales	I	Enoyl-CoA hydratase isomerase	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
MMD1_k127_3019134_9	1121468.AUBR01000002_gene716	3.517e-66	238.0	COG1397@1|root,COG1397@2|Bacteria,1TQXG@1239|Firmicutes,24C2X@186801|Clostridia,42GV9@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
MMD1_k127_3019134_14	289376.THEYE_A0789	4.585e-13	70.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K05337,ko:K17247	-	-	-	-	ko00000	-	-	-	Fer4_13,Ferric_reduct
MMD1_k127_3019134_12	926560.KE387023_gene2277	1.916e-27	113.0	COG4309@1|root,COG4309@2|Bacteria,1WKCP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
MMD1_k127_3019134_7	118163.Ple7327_4592	4.391e-87	301.0	COG4360@1|root,COG4360@2|Bacteria,1G2S9@1117|Cyanobacteria,3VIQF@52604|Pleurocapsales	1117|Cyanobacteria	F	PFAM ATP adenylyltransferase	apa2	-	2.7.7.53	ko:K00988	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	ATP_transf
MMD1_k127_3019134_11	1158338.JNLJ01000001_gene1180	6.189e-29	124.0	COG1573@1|root,COG1573@2|Bacteria,2G41P@200783|Aquificae	200783|Aquificae	L	TIGRFAM Phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
MMD1_k127_3019134_5	439235.Dalk_1929	1.008e-141	467.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2MJ3U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
MMD1_k127_3019134_13	404589.Anae109_0557	2.034e-15	85.0	2BZY2@1|root,2ZMII@2|Bacteria,1P6VB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3019134_10	1121918.ARWE01000001_gene3299	1.481e-53	198.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
MMD1_k127_3019134_8	871963.Desdi_0737	2.771e-72	258.0	COG0500@1|root,COG2226@2|Bacteria,1TT7G@1239|Firmicutes,24E44@186801|Clostridia,263FJ@186807|Peptococcaceae	186801|Clostridia	Q	NOG31153 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3019134_3	443143.GM18_0879	4.494e-143	464.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42UCQ@68525|delta/epsilon subdivisions,2WQ17@28221|Deltaproteobacteria,43V66@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N,FAE1_CUT1_RppA
MMD1_k127_3019134_4	247490.KSU1_B0190	5.207e-143	462.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD1_k127_3019646_4	305700.B447_19829	8.587e-31	123.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria,2KVIC@206389|Rhodocyclales	206389|Rhodocyclales	M	Lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMD1_k127_3019646_1	289376.THEYE_A0738	8.073e-134	434.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_3019646_3	1123376.AUIU01000019_gene1260	6.388e-40	152.0	2DDIC@1|root,32U1K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
MMD1_k127_3019646_0	1232410.KI421416_gene2699	1.963e-225	715.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,42MQD@68525|delta/epsilon subdivisions,2WJJP@28221|Deltaproteobacteria,43UUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sulfate permease family	ychM	-	4.2.1.1	ko:K01673,ko:K03321	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.A.53.3	-	-	Pro_CA,STAS,STAS_2,Sulfate_transp
MMD1_k127_3019646_2	1249627.D779_3681	5.685e-112	375.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,1RM9Q@1236|Gammaproteobacteria,1WW1W@135613|Chromatiales	135613|Chromatiales	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
MMD1_k127_3021073_1	1121920.AUAU01000030_gene2713	6.317e-38	146.0	2E6X5@1|root,331GM@2|Bacteria,3Y5N8@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3021073_2	1282362.AEAC466_13725	1.126e-24	109.0	COG0454@1|root,COG0456@2|Bacteria,1N01I@1224|Proteobacteria,2UJH9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
MMD1_k127_3021073_0	375286.mma_0472	1.661e-98	324.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4729F@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	tctA4	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
MMD1_k127_3033583_12	1894.JOER01000015_gene7908	1.321e-10	67.0	COG3631@1|root,COG3631@2|Bacteria,2II6Y@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
MMD1_k127_3033583_10	1306174.JODP01000005_gene1309	1.083e-24	109.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
MMD1_k127_3033583_6	309799.DICTH_0708	2.282e-67	233.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
MMD1_k127_3033583_9	1123376.AUIU01000014_gene586	1.25e-32	130.0	COG2920@1|root,COG2920@2|Bacteria	2|Bacteria	P	part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
MMD1_k127_3033583_2	690850.Desaf_2977	8.295e-100	333.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria,2M9ST@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
MMD1_k127_3033583_4	1094715.CM001373_gene401	1.008e-75	259.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,1S3MG@1236|Gammaproteobacteria,1JDG0@118969|Legionellales	118969|Legionellales	S	Flavodoxin-like fold	yieF	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
MMD1_k127_3033583_0	243231.GSU0230	2.5e-161	514.0	COG2805@1|root,COG2805@2|Bacteria,1R6FY@1224|Proteobacteria,42MPJ@68525|delta/epsilon subdivisions,2WK57@28221|Deltaproteobacteria,43SCV@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-2	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMD1_k127_3033583_1	269799.Gmet_0261	3.273e-127	428.0	COG1846@1|root,COG1846@2|Bacteria,1NRG9@1224|Proteobacteria,42YC6@68525|delta/epsilon subdivisions,2WTKJ@28221|Deltaproteobacteria,43TP5@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
MMD1_k127_3033583_5	871968.DESME_03860	1.442e-72	267.0	COG5184@1|root,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,2486M@186801|Clostridia,266SK@186807|Peptococcaceae	186801|Clostridia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2
MMD1_k127_3033583_11	351160.RCIX659	2.58e-16	93.0	arCOG03439@1|root,arCOG06738@1|root,arCOG03439@2157|Archaea,arCOG06738@2157|Archaea	2157|Archaea	O	extracellular matrix structural constituent	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	Beta_helix,CARDB,Calx-beta,CarboxypepD_reg,F5_F8_type_C,NosD,Peptidase_S8
MMD1_k127_3033583_8	1157708.KB907466_gene644	7.731e-54	194.0	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,2VSBK@28216|Betaproteobacteria,4AIX6@80864|Comamonadaceae	28216|Betaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
MMD1_k127_3033583_7	1121406.JAEX01000001_gene530	2.495e-58	210.0	COG1011@1|root,COG1011@2|Bacteria,1RJI6@1224|Proteobacteria,42STD@68525|delta/epsilon subdivisions,2WP75@28221|Deltaproteobacteria,2MC02@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
MMD1_k127_3033583_3	690850.Desaf_2566	1.619e-78	266.0	29IJ4@1|root,313M6@2|Bacteria,1R385@1224|Proteobacteria,43DJI@68525|delta/epsilon subdivisions,2X8QT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
MMD1_k127_3037282_2	269799.Gmet_2406	1.654e-165	527.0	COG4591@1|root,COG4591@2|Bacteria,1QXNJ@1224|Proteobacteria,43C4I@68525|delta/epsilon subdivisions,2X7EY@28221|Deltaproteobacteria,43TJA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD1_k127_3037282_6	316067.Geob_2355	6.117e-109	356.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QF5@68525|delta/epsilon subdivisions,2WK2K@28221|Deltaproteobacteria,43TRN@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_3037282_5	269799.Gmet_2408	2.002e-135	442.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,42PK1@68525|delta/epsilon subdivisions,2WJ65@28221|Deltaproteobacteria,43T47@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
MMD1_k127_3037282_11	330214.NIDE1225	4.164e-79	271.0	COG0299@1|root,COG0299@2|Bacteria,3J0MC@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
MMD1_k127_3037282_4	404380.Gbem_2402	1.203e-141	460.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,43RZ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
MMD1_k127_3037282_15	335543.Sfum_2277	3.329e-25	111.0	2E6ZZ@1|root,331J0@2|Bacteria,1ND14@1224|Proteobacteria,42XQ9@68525|delta/epsilon subdivisions,2WT8C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3037282_9	443144.GM21_1061	1.008e-92	316.0	COG1243@1|root,COG1243@2|Bacteria,1MUYS@1224|Proteobacteria,42N2I@68525|delta/epsilon subdivisions,2WKZX@28221|Deltaproteobacteria,43TDM@69541|Desulfuromonadales	28221|Deltaproteobacteria	BK	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_C
MMD1_k127_3037282_13	1144275.COCOR_04243	5.429e-61	221.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria,2YVFW@29|Myxococcales	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
MMD1_k127_3037282_1	289376.THEYE_A0103	5.691e-184	583.0	COG0304@1|root,COG0304@2|Bacteria,3J0DH@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMD1_k127_3037282_14	639282.DEFDS_0153	2.569e-29	118.0	COG0236@1|root,COG0236@2|Bacteria,2GG1C@200930|Deferribacteres	200930|Deferribacteres	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
MMD1_k127_3037282_10	398767.Glov_1936	1.509e-92	311.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,43T1X@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	KR domain	fabG-2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMD1_k127_3037282_7	330214.NIDE0796	2.424e-101	340.0	COG0331@1|root,COG0331@2|Bacteria,3J0IX@40117|Nitrospirae	40117|Nitrospirae	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
MMD1_k127_3037282_3	697281.Mahau_1319	5.216e-146	474.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,42FKR@68295|Thermoanaerobacterales	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
MMD1_k127_3037282_8	1123376.AUIU01000004_gene1163	7.105e-100	333.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
MMD1_k127_3037282_0	289376.THEYE_A0567	2.836e-185	585.0	COG1960@1|root,COG1960@2|Bacteria,3J13U@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
MMD1_k127_3037282_12	330214.NIDE0795	5.208e-70	240.0	COG0332@1|root,COG0332@2|Bacteria,3J0FW@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
MMD1_k127_3046575_0	243231.GSU2626	1.439e-91	314.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,43S79@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,Methyltransf_25
MMD1_k127_3046575_4	1123354.AUDR01000014_gene927	1.507e-36	159.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,1KRNP@119069|Hydrogenophilales	119069|Hydrogenophilales	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N
MMD1_k127_3046575_1	269799.Gmet_3529	5.924e-80	287.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2WPIT@28221|Deltaproteobacteria,43U0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
MMD1_k127_3046575_3	1232410.KI421420_gene3183	5.803e-45	175.0	COG0760@1|root,COG0760@2|Bacteria,1RKBZ@1224|Proteobacteria,42SAP@68525|delta/epsilon subdivisions,2WPWG@28221|Deltaproteobacteria,43SKZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
MMD1_k127_3046575_5	1278073.MYSTI_04477	1.21e-06	59.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2YVS3@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
MMD1_k127_3046575_2	443144.GM21_0197	9.818e-66	232.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,43TS2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
MMD1_k127_3054209_0	330214.NIDE1573	8.978e-50	184.0	COG0314@1|root,COG0314@2|Bacteria,3J1AN@40117|Nitrospirae	40117|Nitrospirae	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
MMD1_k127_3054209_1	1047013.AQSP01000140_gene2495	4.208e-17	89.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMD1_k127_3056015_1	632518.Calow_0401	4.08e-174	556.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,42ERE@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Aminotransferase class I and II	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD1_k127_3056015_11	697281.Mahau_1163	4.155e-37	145.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,42GWU@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
MMD1_k127_3056015_8	671143.DAMO_2311	1.424e-73	257.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
MMD1_k127_3056015_13	1499967.BAYZ01000095_gene4149	2.08e-28	123.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
MMD1_k127_3056015_6	1232410.KI421424_gene1720	2.279e-88	303.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43S42@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	HrcA protein C terminal domain	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
MMD1_k127_3056015_12	555079.Toce_0908	5.646e-30	127.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
MMD1_k127_3056015_0	330214.NIDE1728	2.021e-298	927.0	COG0443@1|root,COG0443@2|Bacteria,3J0D2@40117|Nitrospirae	40117|Nitrospirae	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
MMD1_k127_3056015_3	1232410.KI421424_gene1723	3.725e-135	442.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ central domain	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMD1_k127_3056015_2	1499967.BAYZ01000014_gene6356	1.544e-150	488.0	COG0205@1|root,COG0205@2|Bacteria,2NNXU@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135	2.7.1.11,2.7.1.90	ko:K00850,ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
MMD1_k127_3056015_4	96561.Dole_2859	1.715e-102	343.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2WK0F@28221|Deltaproteobacteria,2MI38@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
MMD1_k127_3056015_10	768670.Calni_0138	1.113e-51	190.0	COG0315@1|root,COG0315@2|Bacteria,2GFIE@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
MMD1_k127_3056015_9	1122947.FR7_2825	1.854e-72	252.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4H41C@909932|Negativicutes	909932|Negativicutes	S	channel protein, hemolysin III family	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
MMD1_k127_3056015_15	204669.Acid345_4724	1.459e-12	74.0	2EA3B@1|root,3348D@2|Bacteria,3Y5J1@57723|Acidobacteria,2JJZE@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3056015_16	1104324.P186_2603	2.129e-08	66.0	arCOG10888@1|root,arCOG10888@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3056015_5	1121468.AUBR01000008_gene2061	1.286e-91	310.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,42F66@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
MMD1_k127_3056015_7	243231.GSU1870	5.616e-78	271.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1NECV@1224|Proteobacteria,42PZK@68525|delta/epsilon subdivisions,2WMIG@28221|Deltaproteobacteria,43W33@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
MMD1_k127_3056217_5	1125863.JAFN01000001_gene1064	3.016e-13	71.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMD1_k127_3056217_0	1121440.AUMA01000009_gene685	3.841e-161	517.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2M994@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMD1_k127_3056217_2	1304885.AUEY01000045_gene250	9.791e-116	398.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,2MN6H@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
MMD1_k127_3056217_3	338966.Ppro_3493	1.804e-86	296.0	COG0226@1|root,COG0226@2|Bacteria,1MW2Z@1224|Proteobacteria,42SWB@68525|delta/epsilon subdivisions,2WPMC@28221|Deltaproteobacteria,43U5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMD1_k127_3056217_1	338963.Pcar_0444	4.82e-125	404.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WK9D@28221|Deltaproteobacteria,43S0Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2395	Fer2_3,Fer4_7,Fer4_8
MMD1_k127_3056217_4	443143.GM18_3410	9.624e-56	195.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria,43TAF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMD1_k127_3061508_7	330214.NIDE3446	4.741e-09	66.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
MMD1_k127_3061508_1	316067.Geob_0755	1.014e-102	349.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,43U1B@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lytic transglycosylase, SLT, LysM and LysM domain-containing	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
MMD1_k127_3061508_4	398767.Glov_1846	2.525e-47	180.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,43SFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
MMD1_k127_3061508_3	292459.STH1332	1.888e-56	216.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
MMD1_k127_3061508_6	1502852.FG94_02403	9.399e-18	90.0	COG0664@1|root,COG0664@2|Bacteria,1N4C9@1224|Proteobacteria,2VVJC@28216|Betaproteobacteria,4761J@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
MMD1_k127_3061508_2	330214.NIDE1410	3.294e-61	224.0	COG0248@1|root,COG0248@2|Bacteria,3J0K5@40117|Nitrospirae	40117|Nitrospirae	FP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
MMD1_k127_3061508_0	56780.SYN_01093	3.03e-151	492.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MRFN@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3061508_9	203275.BFO_2765	8.218e-06	53.0	2EI8K@1|root,33BZY@2|Bacteria,4NXGN@976|Bacteroidetes,2FVB5@200643|Bacteroidia	976|Bacteroidetes	S	TRL-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	TRL
MMD1_k127_3061508_5	330214.NIDE2017	5.748e-19	101.0	COG4380@1|root,COG4380@2|Bacteria	2|Bacteria	D	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2
MMD1_k127_3062131_3	383372.Rcas_0800	2.405e-85	293.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi,3768U@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
MMD1_k127_3062131_2	237368.SCABRO_03060	1.071e-89	306.0	COG0451@1|root,COG0451@2|Bacteria,2IYGP@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
MMD1_k127_3062131_5	1287116.X734_29865	9.738e-50	192.0	COG0500@1|root,COG2226@2|Bacteria,1R42G@1224|Proteobacteria,2U1CY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
MMD1_k127_3062131_8	706587.Desti_3069	8.499e-10	72.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2WS8D@28221|Deltaproteobacteria,2MS9Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
MMD1_k127_3062131_0	96561.Dole_2628	2.392e-138	459.0	COG1032@1|root,COG1032@2|Bacteria,1NRWP@1224|Proteobacteria,42S72@68525|delta/epsilon subdivisions,2WNA6@28221|Deltaproteobacteria,2MKAP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD1_k127_3062131_9	1121438.JNJA01000011_gene1841	4.897e-07	63.0	COG4485@1|root,COG4485@2|Bacteria,1QAT5@1224|Proteobacteria,435A8@68525|delta/epsilon subdivisions,2X97C@28221|Deltaproteobacteria,2MFT4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3062131_10	37727.XP_002148813.1	0.00011	53.0	COG1028@1|root,KOG1611@2759|Eukaryota,3A1BK@33154|Opisthokonta,3P015@4751|Fungi,3QRGN@4890|Ascomycota,20HGM@147545|Eurotiomycetes,3SEK5@5042|Eurotiales	4751|Fungi	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD1_k127_3062131_1	573370.DMR_p1_00150	2.037e-133	451.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,43AF4@68525|delta/epsilon subdivisions,2X5UV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD1_k127_3062131_4	1121440.AUMA01000005_gene2581	7.602e-62	231.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MANW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD1_k127_3062131_6	448385.sce6686	5.667e-31	137.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
MMD1_k127_3070259_3	338963.Pcar_2145	1.561e-76	266.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3070259_4	596152.DesU5LDRAFT_2791	2.947e-62	234.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MR8@68525|delta/epsilon subdivisions,2WIUA@28221|Deltaproteobacteria,2MA08@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMD1_k127_3070259_5	880072.Desac_1220	2.214e-58	214.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WR88@28221|Deltaproteobacteria,2MSCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_3070259_1	1123368.AUIS01000031_gene1418	1.716e-159	509.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,1T8C8@1236|Gammaproteobacteria,2NCKI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_3070259_7	795359.TOPB45_1244	2.222e-19	90.0	2EGXE@1|root,33APK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3070259_0	1123376.AUIU01000019_gene1269	2.363e-256	806.0	COG0466@1|root,COG0466@2|Bacteria,3J0DQ@40117|Nitrospirae	40117|Nitrospirae	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,Lon_C,Response_reg
MMD1_k127_3070259_2	1123392.AQWL01000006_gene638	1.148e-139	461.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VHTK@28216|Betaproteobacteria,1KRZ9@119069|Hydrogenophilales	119069|Hydrogenophilales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMD1_k127_3070259_6	1123392.AQWL01000006_gene639	4.076e-56	197.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KSIU@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3071983_1	316067.Geob_1852	2.372e-71	254.0	COG1418@1|root,COG1418@2|Bacteria,1RK7K@1224|Proteobacteria,42SRK@68525|delta/epsilon subdivisions,2WP5I@28221|Deltaproteobacteria,43UQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Metal-dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMD1_k127_3071983_0	706587.Desti_5047	5.985e-124	420.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
MMD1_k127_3071983_3	1229172.JQFA01000002_gene4200	7.847e-45	170.0	COG0662@1|root,COG0662@2|Bacteria,1G5PK@1117|Cyanobacteria,1HC1C@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD1_k127_3071983_2	316067.Geob_1896	5.919e-68	245.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_9,SpoIIE
MMD1_k127_3073261_3	536227.CcarbDRAFT_3417	4.882e-48	179.0	COG0655@1|root,COG0655@2|Bacteria,1UHW0@1239|Firmicutes,24FZ0@186801|Clostridia,36JW5@31979|Clostridiaceae	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,Flavodoxin_2
MMD1_k127_3073261_0	311403.Arad_0717	9.908e-140	460.0	COG0477@1|root,COG0477@2|Bacteria,1QTTP@1224|Proteobacteria,2TVY9@28211|Alphaproteobacteria,4BC40@82115|Rhizobiaceae	28211|Alphaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD1_k127_3073261_1	251229.Chro_3389	4.971e-56	202.0	2CYFR@1|root,32T44@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
MMD1_k127_3073261_4	443143.GM18_1006	7.295e-40	171.0	COG1520@1|root,COG4932@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3073261_6	443254.Marpi_1007	3.388e-05	57.0	COG1520@1|root,COG1520@2|Bacteria,2GD9T@200918|Thermotogae	200918|Thermotogae	S	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3073261_5	1333856.L686_10650	4.746e-11	66.0	COG5645@1|root,COG5645@2|Bacteria,1QHYN@1224|Proteobacteria,1TFQB@1236|Gammaproteobacteria,1Z36A@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	periplasmic lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1375
MMD1_k127_3073261_2	159087.Daro_3438	8.989e-50	181.0	COG3324@1|root,COG3324@2|Bacteria,1N1P5@1224|Proteobacteria,2W3PV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMD1_k127_3077398_1	123214.PERMA_0513	5.185e-83	287.0	COG2204@1|root,COG2204@2|Bacteria,2G4HS@200783|Aquificae	200783|Aquificae	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
MMD1_k127_3077398_0	330214.NIDE1796	5.798e-180	572.0	COG0448@1|root,COG0448@2|Bacteria,3J0BI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMD1_k127_3084580_1	706587.Desti_0512	5.946e-56	201.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMD1_k127_3084580_0	443143.GM18_4312	3.555e-137	473.0	COG4191@1|root,COG4251@1|root,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
MMD1_k127_3084580_2	460265.Mnod_6354	1.725e-22	102.0	COG0784@1|root,COG2202@1|root,COG3437@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JTVS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
MMD1_k127_3084580_3	404380.Gbem_2945	9.013e-20	91.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria,43STW@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	mcp34H-7	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CZB,HAMP,MCPsignal,PAS_4,dCache_1
MMD1_k127_3092866_29	1123368.AUIS01000003_gene1568	1.803e-16	81.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria	1224|Proteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
MMD1_k127_3092866_31	1232410.KI421412_gene390	5.83e-06	57.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,42VSU@68525|delta/epsilon subdivisions,2WR9P@28221|Deltaproteobacteria,43STH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
MMD1_k127_3092866_21	1123288.SOV_4c05100	6.365e-51	203.0	COG1629@1|root,COG4771@2|Bacteria,1UK28@1239|Firmicutes,4H9AZ@909932|Negativicutes	909932|Negativicutes	P	TonB-dependent receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
MMD1_k127_3092866_22	398767.Glov_3559	8.466e-51	189.0	COG1120@1|root,COG1120@2|Bacteria,1QV5A@1224|Proteobacteria,43CPR@68525|delta/epsilon subdivisions,2X7WZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
MMD1_k127_3092866_15	398767.Glov_3558	3.782e-86	303.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42N28@68525|delta/epsilon subdivisions,2WN16@28221|Deltaproteobacteria,43V85@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
MMD1_k127_3092866_20	398767.Glov_3557	3.988e-54	201.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WKNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
MMD1_k127_3092866_24	555079.Toce_1426	1.048e-46	182.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,42FIR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
MMD1_k127_3092866_8	1163617.SCD_n01491	3.621e-140	451.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30,5.4.2.9	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	-	R00409,R00661	RC00286,RC00287,RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
MMD1_k127_3092866_5	29581.BW37_02264	1.875e-184	583.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VHJZ@28216|Betaproteobacteria,472IE@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Belongs to the citrate synthase family	prpC	-	2.3.3.5	ko:K01659	ko00640,map00640	-	R00931	RC00004,RC00406,RC02827	ko00000,ko00001,ko01000	-	-	-	Citrate_synt
MMD1_k127_3092866_3	1169143.KB911059_gene5251	5.779e-262	812.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria,1K4ZW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
MMD1_k127_3092866_0	1217718.ALOU01000027_gene3690	0.0	1266.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1K16W@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMD1_k127_3092866_1	1125863.JAFN01000001_gene1819	0.0	1019.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WJY2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMD1_k127_3092866_13	1167006.UWK_01572	3.261e-97	327.0	COG0491@1|root,COG0491@2|Bacteria,1R4FA@1224|Proteobacteria,42TD1@68525|delta/epsilon subdivisions,2WPPD@28221|Deltaproteobacteria,2MQ1T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
MMD1_k127_3092866_27	555079.Toce_0471	1.191e-23	106.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,42GYY@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
MMD1_k127_3092866_26	880072.Desac_2161	2.315e-32	136.0	COG1456@1|root,COG1456@2|Bacteria,1R8JC@1224|Proteobacteria,42Q7Q@68525|delta/epsilon subdivisions,2WJXT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Fe-S cluster domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786,FeS
MMD1_k127_3092866_18	443144.GM21_0222	1.77e-71	259.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMD1_k127_3092866_6	443143.GM18_0111	3.708e-167	541.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria	1224|Proteobacteria	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
MMD1_k127_3092866_17	404589.Anae109_1007	1.552e-84	289.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria,2Z0AD@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
MMD1_k127_3092866_19	401526.TcarDRAFT_0620	9.305e-57	207.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4H2SP@909932|Negativicutes	909932|Negativicutes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
MMD1_k127_3092866_23	404589.Anae109_1008	5.739e-48	183.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YV5B@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
MMD1_k127_3092866_16	338963.Pcar_1058	1.482e-84	288.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,43S7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
MMD1_k127_3092866_25	290397.Adeh_2674	2.915e-33	136.0	2EKQ7@1|root,33EDZ@2|Bacteria,1NHK0@1224|Proteobacteria,42VJ3@68525|delta/epsilon subdivisions,2WRIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2845
MMD1_k127_3092866_2	243231.GSU0686	1.538e-262	823.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
MMD1_k127_3092866_12	243231.GSU1765	2.191e-98	334.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,43UK9@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
MMD1_k127_3092866_28	338966.Ppro_2405	3.999e-19	90.0	COG1722@1|root,COG1722@2|Bacteria,1Q1MM@1224|Proteobacteria,42X37@68525|delta/epsilon subdivisions,2WSNI@28221|Deltaproteobacteria,43VHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
MMD1_k127_3092866_9	1499967.BAYZ01000158_gene455	8.324e-118	394.0	COG1570@1|root,COG1570@2|Bacteria,2NNQT@2323|unclassified Bacteria	2|Bacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
MMD1_k127_3092866_11	443144.GM21_3292	5.749e-107	352.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
MMD1_k127_3092866_4	289376.THEYE_A1342	8.749e-187	597.0	COG1418@1|root,COG1418@2|Bacteria,3J0C8@40117|Nitrospirae	40117|Nitrospirae	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
MMD1_k127_3092866_7	1118054.CAGW01000018_gene4278	2.194e-153	497.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,26QG9@186822|Paenibacillaceae	91061|Bacilli	L	ATPase, AAA	yrvN	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
MMD1_k127_3092866_30	880073.Calab_3701	1.143e-10	66.0	COG3027@1|root,COG3027@2|Bacteria,2NQ5R@2323|unclassified Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
MMD1_k127_3092866_10	1121468.AUBR01000030_gene1228	1.379e-107	357.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,42ENW@68295|Thermoanaerobacterales	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
MMD1_k127_3092866_14	1232410.KI421424_gene1653	2.213e-96	327.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,43T29@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
MMD1_k127_3102091_3	429009.Adeg_0545	2.17e-30	129.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,42I3C@68295|Thermoanaerobacterales	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
MMD1_k127_3102091_1	316067.Geob_0698	2.876e-119	405.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,43TUI@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
MMD1_k127_3102091_0	330214.NIDE0990	1.171e-176	574.0	COG0568@1|root,COG0568@2|Bacteria,3J0E4@40117|Nitrospirae	40117|Nitrospirae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMD1_k127_3102091_4	1123376.AUIU01000014_gene560	1.125e-28	124.0	COG1579@1|root,COG1579@2|Bacteria,3J0UV@40117|Nitrospirae	40117|Nitrospirae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
MMD1_k127_3102091_2	644966.Tmar_2073	2.598e-38	148.0	COG0328@1|root,COG0328@2|Bacteria,1VAJW@1239|Firmicutes,24NJ8@186801|Clostridia	186801|Clostridia	L	PFAM ribonuclease H	rnhA	-	3.1.26.4	ko:K03469,ko:K06864	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
MMD1_k127_3105011_1	635013.TherJR_0983	7.23e-88	293.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,2626Y@186807|Peptococcaceae	186801|Clostridia	S	Methionine synthase, cobalamin (vitamin B12)-binding module, cap	mtbC	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
MMD1_k127_3105011_2	760568.Desku_0061	1.553e-46	175.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,24B04@186801|Clostridia,2670T@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM iron-sulfur cluster binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_16,Fer4_7
MMD1_k127_3105011_0	1265505.ATUG01000002_gene1096	2.209e-132	434.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MPY1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
MMD1_k127_3116774_1	635013.TherJR_1783	1.246e-64	229.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,260PG@186807|Peptococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
MMD1_k127_3116774_4	1492738.FEM21_07100	0.0001291	46.0	COG2336@1|root,COG2336@2|Bacteria,4NSWY@976|Bacteroidetes,1I3XG@117743|Flavobacteriia,2NX5Q@237|Flavobacterium	976|Bacteroidetes	T	Transcriptional regulator antitoxin, MazE	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
MMD1_k127_3116774_2	269799.Gmet_1009	1.915e-62	226.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42T3J@68525|delta/epsilon subdivisions,2X5P0@28221|Deltaproteobacteria,43W2U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
MMD1_k127_3116774_3	1007103.AFHW01000008_gene6212	3.651e-12	72.0	29J6J@1|root,3063Z@2|Bacteria,1TZ59@1239|Firmicutes,4I8CC@91061|Bacilli,26ZJQ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3116774_0	1379698.RBG1_1C00001G0186	1.953e-182	581.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2NNNY@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.3.13,2.7.9.1	ko:K01006,ko:K22424	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
MMD1_k127_3116789_2	1123278.KB893387_gene4430	2.37e-07	53.0	COG1577@1|root,COG1874@1|root,COG3391@1|root,COG1577@2|Bacteria,COG1874@2|Bacteria,COG3391@2|Bacteria,4PPRK@976|Bacteroidetes,47TYG@768503|Cytophagia	976|Bacteroidetes	G	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3116789_1	243231.GSU1055	2.604e-21	98.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,42NQX@68525|delta/epsilon subdivisions,2WKDB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
MMD1_k127_3116789_0	443143.GM18_4487	2.982e-74	261.0	COG2897@1|root,COG2897@2|Bacteria,1QQTJ@1224|Proteobacteria,43A4S@68525|delta/epsilon subdivisions,2WUSF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMD1_k127_3116973_1	717605.Theco_2409	1.765e-79	270.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,26RUU@186822|Paenibacillaceae	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
MMD1_k127_3116973_2	1267535.KB906767_gene825	1.199e-75	265.0	COG1940@1|root,COG1940@2|Bacteria,3Y4DD@57723|Acidobacteria,2JJ4T@204432|Acidobacteriia	204432|Acidobacteriia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMD1_k127_3116973_5	1223545.GS4_03_00090	1.61e-05	54.0	2EGD2@1|root,33A4V@2|Bacteria,2GWY9@201174|Actinobacteria,4GECV@85026|Gordoniaceae	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
MMD1_k127_3116973_4	706587.Desti_4616	8.081e-38	155.0	COG2881@1|root,COG2881@2|Bacteria,1N6EP@1224|Proteobacteria,42U9Y@68525|delta/epsilon subdivisions,2WQGR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1,zinc_ribbon_4
MMD1_k127_3116973_3	1125863.JAFN01000001_gene2998	4.228e-64	224.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WN91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
MMD1_k127_3116973_0	1125863.JAFN01000001_gene1676	4.305e-86	287.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42QCV@68525|delta/epsilon subdivisions,2WJP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMD1_k127_3160542_4	204669.Acid345_1220	0.0003596	49.0	COG0457@1|root,COG0457@2|Bacteria,3Y6TV@57723|Acidobacteria,2JMCU@204432|Acidobacteriia	204432|Acidobacteriia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_16
MMD1_k127_3160542_0	398767.Glov_2173	1.463e-147	474.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
MMD1_k127_3160542_2	1232410.KI421415_gene3115	1.437e-50	191.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,43SHR@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	RuvA, C-terminal domain	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
MMD1_k127_3160542_3	443144.GM21_0932	5.509e-48	179.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,43US0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
MMD1_k127_3160542_1	1499967.BAYZ01000068_gene1977	1.517e-75	258.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
MMD1_k127_3161113_0	1121440.AUMA01000009_gene683	1.022e-129	420.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria,2MA30@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
MMD1_k127_3161113_1	1121440.AUMA01000009_gene682	2.605e-112	370.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria,2M9HK@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	pfam abc	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
MMD1_k127_3161113_2	1125863.JAFN01000001_gene1061	1.381e-93	313.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42MSC@68525|delta/epsilon subdivisions,2WJAH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
MMD1_k127_3161113_3	1121440.AUMA01000009_gene680	7.656e-77	263.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,42R80@68525|delta/epsilon subdivisions,2WMW6@28221|Deltaproteobacteria,2ME90@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
MMD1_k127_3161113_4	316067.Geob_1150	2.437e-62	218.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,43U78@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
MMD1_k127_3168122_0	1121468.AUBR01000003_gene619	1.348e-93	317.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,42F6N@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
MMD1_k127_3168122_2	243231.GSU3625	4.897e-32	139.0	COG1333@1|root,COG1333@2|Bacteria,1RIJF@1224|Proteobacteria,42T2N@68525|delta/epsilon subdivisions,2WPA1@28221|Deltaproteobacteria,43VTI@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	ResB
MMD1_k127_3168122_1	404380.Gbem_3967	1.957e-58	209.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
MMD1_k127_3173840_1	760568.Desku_1548	5.88e-119	389.0	COG1060@1|root,COG1060@2|Bacteria,1TRHG@1239|Firmicutes,247Z2@186801|Clostridia,2609W@186807|Peptococcaceae	186801|Clostridia	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1,2.5.1.77	ko:K11779,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
MMD1_k127_3173840_0	246194.CHY_1806	3.666e-140	456.0	COG1060@1|root,COG1060@2|Bacteria,1TQNG@1239|Firmicutes,24AHE@186801|Clostridia,42FB5@68295|Thermoanaerobacterales	186801|Clostridia	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
MMD1_k127_3183343_0	247490.KSU1_C1305	0.0	1009.0	COG0296@1|root,COG0296@2|Bacteria,2IXS1@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
MMD1_k127_3183343_2	1185876.BN8_01300	7.62e-35	140.0	COG3631@1|root,COG3631@2|Bacteria,4NVWJ@976|Bacteroidetes,47WCU@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
MMD1_k127_3183343_1	883.DvMF_1524	1.569e-65	228.0	COG1853@1|root,COG1853@2|Bacteria,1RBSR@1224|Proteobacteria,42R0G@68525|delta/epsilon subdivisions,2WMYE@28221|Deltaproteobacteria,2MAM7@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM flavin reductase domain protein FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
MMD1_k127_3183343_3	589865.DaAHT2_2395	1.038e-16	81.0	COG0484@1|root,COG1426@1|root,COG0484@2|Bacteria,COG1426@2|Bacteria,1NCYU@1224|Proteobacteria,42WS1@68525|delta/epsilon subdivisions,2WSDX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,HTH_25
MMD1_k127_31926_1	215803.DB30_2166	5.704e-104	349.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
MMD1_k127_31926_2	330214.NIDE1347	3.57e-17	82.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	racA	-	-	ko:K11686,ko:K13640,ko:K18997	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	DUF1836,MerR_1,MerR_2
MMD1_k127_31926_0	555779.Dthio_PD3238	7.01e-255	799.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2M9QY@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
MMD1_k127_3195649_1	56780.SYN_01995	6.477e-177	561.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD1_k127_3195649_18	443143.GM18_3636	5.932e-17	85.0	2DRRJ@1|root,33CRQ@2|Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_3195649_6	1266925.JHVX01000007_gene2369	4.242e-141	459.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VH8N@28216|Betaproteobacteria,3725C@32003|Nitrosomonadales	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
MMD1_k127_3195649_14	589865.DaAHT2_0405	5.573e-79	274.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,42UZB@68525|delta/epsilon subdivisions,2WQSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
MMD1_k127_3195649_12	1121918.ARWE01000001_gene1125	1.084e-85	303.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42NE2@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
MMD1_k127_3195649_4	589865.DaAHT2_0407	5.55e-149	485.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3195649_19	1123372.AUIT01000026_gene1292	1.96e-15	85.0	COG2204@1|root,COG2204@2|Bacteria,2GHIR@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3195649_0	243231.GSU2502	2e-269	862.0	COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
MMD1_k127_3195649_2	404589.Anae109_1828	2.384e-173	572.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
MMD1_k127_3195649_3	1131269.AQVV01000048_gene2100	1.28e-155	511.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000048_gene2100|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3195649_11	909663.KI867150_gene213	2.681e-86	309.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
MMD1_k127_3195649_20	398767.Glov_2384	2.018e-15	84.0	2ATWF@1|root,31JFP@2|Bacteria,1RK55@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3195649_10	909663.KI867150_gene213	6.893e-97	341.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
MMD1_k127_3195649_7	909663.KI867150_gene213	1.065e-138	466.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
MMD1_k127_3195649_15	316067.Geob_3167	5.86e-68	242.0	COG3391@1|root,COG3391@2|Bacteria,1NW4P@1224|Proteobacteria,42Z3T@68525|delta/epsilon subdivisions,2WV9X@28221|Deltaproteobacteria,43VSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD1_k127_3195649_13	243231.GSU2503	4.614e-83	292.0	28WYN@1|root,2ZIXP@2|Bacteria,1NRMH@1224|Proteobacteria,42YM3@68525|delta/epsilon subdivisions	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_3195649_5	243231.GSU2501	1.756e-143	467.0	28WYN@1|root,30ZZ9@2|Bacteria,1NPVB@1224|Proteobacteria,42XW6@68525|delta/epsilon subdivisions,2WTBQ@28221|Deltaproteobacteria,43VPR@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_3195649_8	316067.Geob_3165	5.521e-119	401.0	COG3391@1|root,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WSJC@28221|Deltaproteobacteria,43VUI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
MMD1_k127_3195649_9	243231.GSU2499	2.509e-115	399.0	2AIHE@1|root,318Z9@2|Bacteria,1NWQ1@1224|Proteobacteria,42ZTQ@68525|delta/epsilon subdivisions,2WV9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3195649_16	316067.Geob_3163	1.415e-59	213.0	COG4380@1|root,COG4380@2|Bacteria,1NJYS@1224|Proteobacteria,42X1E@68525|delta/epsilon subdivisions,2WTEE@28221|Deltaproteobacteria,43VPV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative bacterial lipoprotein (DUF799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF799
MMD1_k127_3195649_17	243231.GSU2497	1.634e-35	147.0	2EUMZ@1|root,33N3U@2|Bacteria,1NUNW@1224|Proteobacteria,42ZFD@68525|delta/epsilon subdivisions,2WV00@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3195649_21	1123508.JH636442_gene4368	2.047e-07	62.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,FG-GAP_2,Flg_new,HYR,Laminin_G_3,PQQ_2,SBBP
MMD1_k127_3239825_3	316067.Geob_1467	2.74e-45	176.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
MMD1_k127_3239825_2	290397.Adeh_3050	1.295e-67	240.0	COG1215@1|root,COG1215@2|Bacteria,1QVTJ@1224|Proteobacteria	1224|Proteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	wbyL	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
MMD1_k127_3239825_0	96561.Dole_1969	1.063e-136	445.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WP9Y@28221|Deltaproteobacteria,2MKB4@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMD1_k127_3239825_1	118161.KB235922_gene4546	3.974e-136	439.0	COG1089@1|root,COG1089@2|Bacteria,1G0M4@1117|Cyanobacteria,3VIYC@52604|Pleurocapsales	2|Bacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
MMD1_k127_3239825_4	497965.Cyan7822_5352	1.458e-24	104.0	COG1089@1|root,COG1089@2|Bacteria,1G0M4@1117|Cyanobacteria,3KGR9@43988|Cyanothece	2|Bacteria	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
MMD1_k127_3258866_1	1192868.CAIU01000003_gene318	0.0004736	51.0	COG2197@1|root,COG2197@2|Bacteria,1R9ZF@1224|Proteobacteria,2U9TQ@28211|Alphaproteobacteria,43QW6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMD1_k127_3258866_0	237368.SCABRO_00865	3.476e-11	69.0	COG1895@1|root,COG1895@2|Bacteria,2J4E4@203682|Planctomycetes	203682|Planctomycetes	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
MMD1_k127_3285546_1	1121422.AUMW01000009_gene3273	4.091e-127	411.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,260R6@186807|Peptococcaceae	186801|Clostridia	C	NADH dehydrogenase	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
MMD1_k127_3285546_0	555779.Dthio_PD3230	3.538e-145	467.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,43BP2@68525|delta/epsilon subdivisions,2WK8X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	molybdopterin oxidoreductase Fe4S4 region	sfrA	-	1.17.1.10	ko:K05299	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_10,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMD1_k127_3292198_0	269797.Mbar_A1599	1.765e-91	316.0	COG0247@1|root,arCOG00333@2157|Archaea,2Y85G@28890|Euryarchaeota,2N92Q@224756|Methanomicrobia	224756|Methanomicrobia	C	Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit	hdrD	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576	1.8.98.1	ko:K08264	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R04540	RC00011	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
MMD1_k127_3292198_2	349124.Hhal_1957	4.745e-24	111.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,1RYZ2@1236|Gammaproteobacteria,1WW9H@135613|Chromatiales	135613|Chromatiales	C	PFAM Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
MMD1_k127_3292198_3	635013.TherJR_0868	1.624e-17	87.0	arCOG03368@1|root,331XD@2|Bacteria,1VHY0@1239|Firmicutes,24SSZ@186801|Clostridia,262UP@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3292198_1	1121430.JMLG01000016_gene367	2.668e-75	258.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,260RG@186807|Peptococcaceae	186801|Clostridia	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
MMD1_k127_3311139_0	1131269.AQVV01000011_gene2518	6.789e-227	726.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	parC	GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363	5.99.1.3	ko:K02469,ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMD1_k127_3311139_2	114615.BRADO6457	1.747e-78	265.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,2U5FG@28211|Alphaproteobacteria,3JY4S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
MMD1_k127_3311139_3	706587.Desti_3016	2.932e-63	221.0	COG2210@1|root,COG2210@2|Bacteria,1QZTN@1224|Proteobacteria,431JI@68525|delta/epsilon subdivisions,2WWC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,TusA
MMD1_k127_3311139_4	566466.NOR53_3166	1.413e-45	180.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RW40@1236|Gammaproteobacteria,1J8F4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
MMD1_k127_3311139_1	1499967.BAYZ01000076_gene837	7.582e-106	352.0	COG0123@1|root,COG0123@2|Bacteria,2NP8V@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
MMD1_k127_3339803_0	1151122.AQYD01000005_gene3206	1.678e-91	305.0	COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4FQXM@85023|Microbacteriaceae	201174|Actinobacteria	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
MMD1_k127_3339803_1	56107.Cylst_1637	1.049e-38	162.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1GITF@1117|Cyanobacteria,1HR1J@1161|Nostocales	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
MMD1_k127_336266_10	167539.Pro_0150	4.917e-16	91.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,1MKDA@1212|Prochloraceae	1117|Cyanobacteria	T	Alternative locus ID	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD1_k127_336266_11	1384056.N787_14015	4.883e-10	70.0	COG0643@1|root,COG0784@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1X3AY@135614|Xanthomonadales	135614|Xanthomonadales	T	Chemotaxis protein histidine kinase and related kinases	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
MMD1_k127_336266_5	903818.KI912269_gene201	1.642e-81	286.0	COG0664@1|root,COG1295@1|root,COG0664@2|Bacteria,COG1295@2|Bacteria,3Y3RZ@57723|Acidobacteria	57723|Acidobacteria	K	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
MMD1_k127_336266_1	944480.ATUV01000001_gene503	5.22e-208	661.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42P0M@68525|delta/epsilon subdivisions,2WJMC@28221|Deltaproteobacteria,2M6V7@213113|Desulfurellales	28221|Deltaproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
MMD1_k127_336266_6	269799.Gmet_0515	7.088e-79	277.0	COG0053@1|root,COG0053@2|Bacteria,1ND3V@1224|Proteobacteria,431R3@68525|delta/epsilon subdivisions,2WWYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
MMD1_k127_336266_8	1041930.Mtc_1090	7.303e-24	105.0	arCOG11656@1|root,arCOG11656@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_336266_2	330214.NIDE0856	2.631e-110	365.0	COG0306@1|root,COG0306@2|Bacteria,3J1D1@40117|Nitrospirae	40117|Nitrospirae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
MMD1_k127_336266_3	1437425.CSEC_0969	5.651e-104	347.0	COG0306@1|root,COG0306@2|Bacteria,2JH20@204428|Chlamydiae	204428|Chlamydiae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
MMD1_k127_336266_7	671143.DAMO_1095	3.615e-47	179.0	COG1392@1|root,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	MA20_27875	-	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
MMD1_k127_336266_0	868595.Desca_2245	1.566e-246	774.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
MMD1_k127_336266_9	747365.Thena_1606	2.057e-21	99.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,42GYY@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
MMD1_k127_336266_4	700598.Niako_0486	6.278e-90	310.0	COG4447@1|root,COG4447@2|Bacteria,4NRP7@976|Bacteroidetes,1IU78@117747|Sphingobacteriia	976|Bacteroidetes	UW	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
MMD1_k127_336695_0	580332.Slit_1176	0.0	1370.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria	28216|Betaproteobacteria	S	alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,MG1,Thiol-ester_cl
MMD1_k127_336695_1	1203606.HMPREF1526_02900	0.0006343	43.0	COG1649@1|root,COG2247@1|root,COG1649@2|Bacteria,COG2247@2|Bacteria,1V7X5@1239|Firmicutes,25G2M@186801|Clostridia	186801|Clostridia	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
MMD1_k127_3394245_8	479434.Sthe_2438	2.416e-28	123.0	COG0363@1|root,COG0363@2|Bacteria,2G6S0@200795|Chloroflexi,27YBD@189775|Thermomicrobia	189775|Thermomicrobia	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
MMD1_k127_3394245_1	1121439.dsat_0894	3.283e-161	523.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria,2M9K4@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
MMD1_k127_3394245_3	596152.DesU5LDRAFT_0652	5.168e-114	379.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,2M90T@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
MMD1_k127_3394245_6	1286171.EAL2_c19160	1.064e-85	295.0	COG1023@1|root,COG1023@2|Bacteria,1UMK1@1239|Firmicutes,25GJP@186801|Clostridia	186801|Clostridia	C	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
MMD1_k127_3394245_5	269799.Gmet_0297	9.315e-86	299.0	COG0348@1|root,COG0348@2|Bacteria,1MY5M@1224|Proteobacteria,42QNC@68525|delta/epsilon subdivisions,2WMUV@28221|Deltaproteobacteria,43UH6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	yccM-2	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_5
MMD1_k127_3394245_2	589865.DaAHT2_2661	5.394e-147	475.0	COG0446@1|root,COG0446@2|Bacteria,1QSGB@1224|Proteobacteria,43A36@68525|delta/epsilon subdivisions,2WZXC@28221|Deltaproteobacteria,2MP72@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMD1_k127_3394245_13	2423.NA23_0201010	9.637e-05	49.0	COG2168@1|root,COG2168@2|Bacteria,2GDEY@200918|Thermotogae	200918|Thermotogae	P	sulfur relay protein TusB DsrH	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
MMD1_k127_3394245_12	573063.Metin_1213	2.452e-06	55.0	COG1553@1|root,arCOG02068@2157|Archaea,2XYJ8@28890|Euryarchaeota,23R0A@183939|Methanococci	183939|Methanococci	P	PFAM DsrE family protein	-	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
MMD1_k127_3394245_7	330214.NIDE3221	8.397e-80	280.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3394245_9	1125863.JAFN01000001_gene3430	4.018e-23	102.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	3.6.4.12	ko:K03655,ko:K03892,ko:K21903	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	HTH_20,HTH_5
MMD1_k127_3394245_0	1487953.JMKF01000028_gene1253	3.22e-198	646.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H9JN@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GAF,GGDEF,PAS_3,PAS_9,Response_reg
MMD1_k127_3394245_11	272134.KB731324_gene6219	1.284e-09	68.0	COG0455@1|root,COG2199@1|root,COG0455@2|Bacteria,COG3706@2|Bacteria,1G5AU@1117|Cyanobacteria	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,Response_reg
MMD1_k127_3394245_10	745310.G432_17900	5.454e-11	75.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,2K5JY@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
MMD1_k127_3394245_4	234267.Acid_4340	1.479e-87	308.0	COG1055@1|root,COG1055@2|Bacteria,3Y5VM@57723|Acidobacteria	57723|Acidobacteria	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	ArsB,CitMHS
MMD1_k127_3399043_2	316067.Geob_0160	1.069e-109	363.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,43TEK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA-1	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
MMD1_k127_3399043_1	639282.DEFDS_0964	1.248e-176	566.0	COG1541@1|root,COG1541@2|Bacteria,2GEXG@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
MMD1_k127_3399043_4	247490.KSU1_C0656	1.537e-48	177.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	catA	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C
MMD1_k127_3399043_3	1232410.KI421424_gene1670	1.971e-79	272.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2WMCA@28221|Deltaproteobacteria,43SHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lytic transglycolase	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
MMD1_k127_3399043_6	247490.KSU1_C0465	1.979e-27	114.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
MMD1_k127_3399043_5	1469607.KK073768_gene4603	1.158e-45	169.0	COG1047@1|root,COG1047@2|Bacteria,1G5R4@1117|Cyanobacteria,1HSF7@1161|Nostocales	1117|Cyanobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
MMD1_k127_3399043_8	1173024.KI912152_gene807	5.49e-13	77.0	2DQJ8@1|root,3377K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3399043_0	1167006.UWK_01240	8.893e-231	727.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,42T70@68525|delta/epsilon subdivisions,2WUHA@28221|Deltaproteobacteria,2MPSU@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
MMD1_k127_3426515_26	1235755.ANAM01000006_gene2315	3.435e-05	52.0	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,4HKN1@91061|Bacilli,4H1AZ@90964|Staphylococcaceae	91061|Bacilli	S	Hfq protein	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
MMD1_k127_3426515_24	289376.THEYE_A1748	2.507e-13	76.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
MMD1_k127_3426515_13	1232410.KI421412_gene383	2.461e-74	255.0	COG0778@1|root,COG0778@2|Bacteria,1RECN@1224|Proteobacteria,43DS9@68525|delta/epsilon subdivisions,2WNXD@28221|Deltaproteobacteria,43TGM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD1_k127_3426515_18	316067.Geob_3101	4.184e-60	213.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42SDH@68525|delta/epsilon subdivisions,2WPPH@28221|Deltaproteobacteria,43V7T@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
MMD1_k127_3426515_1	909663.KI867150_gene1244	7.491e-153	493.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2WKX7@28221|Deltaproteobacteria,2MQUQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
MMD1_k127_3426515_21	264462.Bd1397	9.298e-27	113.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2MU6W@213481|Bdellovibrionales,2WQKU@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	PFAM RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMD1_k127_3426515_25	338963.Pcar_2255	1.075e-12	70.0	COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,42XSC@68525|delta/epsilon subdivisions,2WT18@28221|Deltaproteobacteria,43SSB@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein S21	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
MMD1_k127_3426515_19	1294265.JCM21738_1194	1.344e-34	142.0	2CRK8@1|root,32SP8@2|Bacteria,1VP9M@1239|Firmicutes,4HR71@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4253)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4253
MMD1_k127_3426515_7	1232410.KI421424_gene1590	2.748e-94	321.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,43C4K@68525|delta/epsilon subdivisions,2X7F1@28221|Deltaproteobacteria,43TX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
MMD1_k127_3426515_4	868595.Desca_0555	7.015e-139	458.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,263E4@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K02481,ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3426515_23	858215.Thexy_0590	6.029e-14	77.0	COG2608@1|root,COG2608@2|Bacteria,1VERB@1239|Firmicutes,24U5J@186801|Clostridia,42H68@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Heavy metal transport detoxification protein	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
MMD1_k127_3426515_22	1304888.ATWF01000001_gene623	3.172e-26	119.0	2DMMW@1|root,32SIJ@2|Bacteria,2GFD5@200930|Deferribacteres	200930|Deferribacteres	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3426515_14	1122947.FR7_3138	9.374e-67	239.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4H336@909932|Negativicutes	909932|Negativicutes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
MMD1_k127_3426515_5	330214.NIDE0419	1.114e-136	443.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,3J0A9@40117|Nitrospirae	40117|Nitrospirae	E	Chorismate mutase type II	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
MMD1_k127_3426515_6	671143.DAMO_1203	2.9e-120	396.0	COG0079@1|root,COG0079@2|Bacteria,2NNZK@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD1_k127_3426515_3	330214.NIDE0421	5.436e-143	462.0	COG2876@1|root,COG2876@2|Bacteria,3J0A5@40117|Nitrospirae	40117|Nitrospirae	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
MMD1_k127_3426515_11	1121918.ARWE01000001_gene1094	3.773e-81	279.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2WJZ7@28221|Deltaproteobacteria,43S3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
MMD1_k127_3426515_2	443143.GM18_3293	1.612e-149	484.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria,43TXZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
MMD1_k127_3426515_27	404380.Gbem_3997	0.0006244	52.0	COG1413@1|root,COG1413@2|Bacteria,1P4H5@1224|Proteobacteria,42WD8@68525|delta/epsilon subdivisions,2WRJT@28221|Deltaproteobacteria,43UWV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
MMD1_k127_3426515_16	398767.Glov_2147	3.784e-65	235.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria,43VZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Cytidylate kinase	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
MMD1_k127_3426515_10	635013.TherJR_1590	2.681e-87	297.0	COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,26081@186807|Peptococcaceae	186801|Clostridia	IJM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
MMD1_k127_3426515_0	330214.NIDE0426	1.231e-205	654.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,3J0CA@40117|Nitrospirae	40117|Nitrospirae	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
MMD1_k127_3426515_12	330214.NIDE0427	2.597e-80	281.0	COG0616@1|root,COG0616@2|Bacteria,3J0J0@40117|Nitrospirae	40117|Nitrospirae	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
MMD1_k127_3426515_20	330214.NIDE0428	1.132e-29	120.0	COG0776@1|root,COG0776@2|Bacteria,3J19J@40117|Nitrospirae	40117|Nitrospirae	L	bacterial (prokaryotic) histone like domain	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMD1_k127_3426515_15	404589.Anae109_1810	2.385e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,42PU2@68525|delta/epsilon subdivisions,2X60T@28221|Deltaproteobacteria,2Z327@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMD1_k127_3426515_8	290397.Adeh_1998	3.736e-88	313.0	COG4585@1|root,COG4585@2|Bacteria,1N0JE@1224|Proteobacteria,42UG3@68525|delta/epsilon subdivisions,2WQFT@28221|Deltaproteobacteria,2Z1DF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
MMD1_k127_3426515_17	290397.Adeh_2001	2.21e-62	227.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
MMD1_k127_3426515_9	290397.Adeh_2002	8.069e-88	308.0	COG3005@1|root,COG3005@2|Bacteria,1QYG3@1224|Proteobacteria,43CC8@68525|delta/epsilon subdivisions,2X7N4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_3526642_4	880072.Desac_0971	1.227e-10	71.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PpiC-type peptidyl-prolyl cis-trans isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
MMD1_k127_3526642_3	243164.DET0127	8.217e-18	98.0	COG2203@1|root,COG4191@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,2G8WY@200795|Chloroflexi,34D2J@301297|Dehalococcoidia	301297|Dehalococcoidia	T	GAF domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
MMD1_k127_3526642_2	713587.THITH_16870	5.278e-23	115.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1QEEZ@1224|Proteobacteria,1RP06@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	hmsT	-	-	-	-	-	-	-	-	-	-	iPC815.YPO0425	GGDEF
MMD1_k127_3526642_0	289376.THEYE_A1041	1.058e-102	370.0	COG4775@1|root,COG4775@2|Bacteria,3J0AC@40117|Nitrospirae	40117|Nitrospirae	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
MMD1_k127_3526642_1	1232410.KI421412_gene339	3.057e-70	244.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42QBD@68525|delta/epsilon subdivisions,2WM4P@28221|Deltaproteobacteria,43T7G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
MMD1_k127_3645064_2	335543.Sfum_0360	9.498e-29	120.0	COG0789@1|root,COG0789@2|Bacteria,1NP97@1224|Proteobacteria,43DNH@68525|delta/epsilon subdivisions,2X38J@28221|Deltaproteobacteria,2MSE8@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMD1_k127_3645064_0	398767.Glov_2275	4.996e-61	219.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,43T44@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
MMD1_k127_3645064_1	2325.TKV_c19910	1.977e-42	163.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,42G31@68295|Thermoanaerobacterales	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
MMD1_k127_3645064_3	2325.TKV_c19900	3.303e-10	64.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,42FHP@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
MMD1_k127_3654062_1	330214.NIDE3548	5.599e-169	541.0	COG0104@1|root,COG0104@2|Bacteria,3J0FV@40117|Nitrospirae	40117|Nitrospirae	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
MMD1_k127_3654062_0	1125863.JAFN01000001_gene1833	1.881e-179	576.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
MMD1_k127_3654062_2	330214.NIDE3444	2.465e-39	147.0	COG0075@1|root,COG0075@2|Bacteria,3J0FC@40117|Nitrospirae	40117|Nitrospirae	E	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMD1_k127_3654483_3	240016.ABIZ01000001_gene2316	6.027e-23	108.0	2EKXK@1|root,33EM4@2|Bacteria,46WCN@74201|Verrucomicrobia,2IUG6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3654483_1	56780.SYN_00415	7.96e-69	250.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,2MQIX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Permease YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
MMD1_k127_3654483_2	316067.Geob_1523	4.996e-65	237.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,43T2W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
MMD1_k127_3654483_0	443143.GM18_0414	1.94e-138	456.0	2EWA0@1|root,33PNR@2|Bacteria,1NSPR@1224|Proteobacteria,42YN1@68525|delta/epsilon subdivisions,2WTJI@28221|Deltaproteobacteria,43U3D@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_366454_4	471854.Dfer_0264	6.235e-05	51.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
MMD1_k127_366454_0	941449.dsx2_1906	2.306e-93	316.0	COG0515@1|root,COG0515@2|Bacteria,1MVPF@1224|Proteobacteria,42PCV@68525|delta/epsilon subdivisions,2WJHA@28221|Deltaproteobacteria,2M8MX@213115|Desulfovibrionales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_366454_3	1121440.AUMA01000008_gene902	2.632e-20	98.0	COG0589@1|root,COG0589@2|Bacteria,1N5TF@1224|Proteobacteria,42TXC@68525|delta/epsilon subdivisions,2WR1C@28221|Deltaproteobacteria,2MGN8@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_366454_2	555079.Toce_0471	1.153e-32	131.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,42GYY@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
MMD1_k127_366454_1	1232410.KI421418_gene2366	5.729e-86	289.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,43SXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
MMD1_k127_3667716_4	555779.Dthio_PD3229	9.451e-162	520.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,2M8TZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMD1_k127_3667716_28	644282.Deba_0987	2.542e-12	77.0	COG0500@1|root,COG2226@2|Bacteria,1NHMR@1224|Proteobacteria,42XMB@68525|delta/epsilon subdivisions,2WT6Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Ogr/Delta-like zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	Ogr_Delta
MMD1_k127_3667716_11	1379281.AVAG01000023_gene1915	5.368e-84	284.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2M9B4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMD1_k127_3667716_19	1396418.BATQ01000136_gene3705	9.229e-65	237.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
MMD1_k127_3667716_26	1449126.JQKL01000028_gene2588	1.583e-23	107.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,24NPX@186801|Clostridia	186801|Clostridia	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
MMD1_k127_3667716_24	338969.Rfer_0260	4.915e-41	165.0	COG3005@1|root,COG3005@2|Bacteria,1NBYF@1224|Proteobacteria	1224|Proteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_3667716_13	1123376.AUIU01000007_gene1193	2.698e-76	261.0	COG0177@1|root,COG0177@2|Bacteria,3J0K6@40117|Nitrospirae	40117|Nitrospirae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
MMD1_k127_3667716_22	272123.Anacy_4556	6.525e-44	168.0	COG4446@1|root,COG4446@2|Bacteria,1G6W2@1117|Cyanobacteria,1HNRG@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
MMD1_k127_3667716_17	1121405.dsmv_0592	5.403e-71	246.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,42RU9@68525|delta/epsilon subdivisions,2WNP7@28221|Deltaproteobacteria,2MJU6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
MMD1_k127_3667716_1	690850.Desaf_0090	9.249e-248	779.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2M9FP@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
MMD1_k127_3667716_15	269799.Gmet_2456	9.775e-74	256.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,42R7A@68525|delta/epsilon subdivisions,2WN7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMD1_k127_3667716_25	864702.OsccyDRAFT_0902	3.116e-25	108.0	COG0599@1|root,COG0599@2|Bacteria,1G8UR@1117|Cyanobacteria,1HFV7@1150|Oscillatoriales	1117|Cyanobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
MMD1_k127_3667716_9	575540.Isop_3507	1.211e-98	337.0	COG0535@1|root,COG0535@2|Bacteria,2IXC0@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Radical_SAM
MMD1_k127_3667716_18	96561.Dole_1611	6.081e-69	243.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,42RFG@68525|delta/epsilon subdivisions,2WPKN@28221|Deltaproteobacteria,2MK0P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
MMD1_k127_3667716_14	269799.Gmet_0349	4.362e-76	265.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WMNG@28221|Deltaproteobacteria,43UNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
MMD1_k127_3667716_3	382464.ABSI01000012_gene2146	5.341e-167	546.0	COG1593@1|root,COG1593@2|Bacteria	2|Bacteria	G	mannitol 2-dehydrogenase activity	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM,DctQ
MMD1_k127_3667716_16	382464.ABSI01000013_gene1504	6.554e-72	255.0	COG1638@1|root,COG1638@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
MMD1_k127_3667716_12	335543.Sfum_2673	1.538e-79	278.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
MMD1_k127_3667716_0	690850.Desaf_1218	0.0	1532.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2M8T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
MMD1_k127_3667716_29	1254432.SCE1572_34565	7.398e-05	52.0	COG4786@1|root,COG4786@2|Bacteria	2|Bacteria	N	Flagellar basal body rod	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF2950,Flg_bb_rod,Flg_bbr_C
MMD1_k127_3667716_5	335543.Sfum_2866	6.149e-157	509.0	COG2204@1|root,COG2204@2|Bacteria,1QYWF@1224|Proteobacteria,43CD6@68525|delta/epsilon subdivisions,2X7P0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
MMD1_k127_3667716_8	1125863.JAFN01000001_gene2253	1.614e-130	432.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3667716_20	290397.Adeh_1907	1.171e-47	188.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria,2YU4V@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
MMD1_k127_3667716_23	767817.Desgi_3255	4.854e-41	157.0	COG2761@1|root,COG2761@2|Bacteria,1TRSS@1239|Firmicutes,25D1S@186801|Clostridia	186801|Clostridia	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
MMD1_k127_3667716_27	756499.Desde_1482	1.952e-20	98.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,2631I@186807|Peptococcaceae	186801|Clostridia	I	PFAM PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
MMD1_k127_3667716_7	243231.GSU2528	1.112e-133	444.0	COG3712@1|root,COG3712@2|Bacteria,1N941@1224|Proteobacteria	1224|Proteobacteria	PT	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	FecR
MMD1_k127_3667716_21	56780.SYN_00378	1.985e-47	182.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,42U9T@68525|delta/epsilon subdivisions,2WQPQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
MMD1_k127_3667716_6	1304888.ATWF01000001_gene1364	2.552e-152	496.0	COG1249@1|root,COG1249@2|Bacteria,2GF91@200930|Deferribacteres	200930|Deferribacteres	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMD1_k127_3667716_10	1121430.JMLG01000026_gene27	1.389e-91	313.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,260T7@186807|Peptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
MMD1_k127_3667716_2	290397.Adeh_2699	1.779e-192	613.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
MMD1_k127_3670568_3	1232410.KI421428_gene968	1.042e-132	432.0	COG0535@1|root,COG0535@2|Bacteria,1R58E@1224|Proteobacteria,42NSA@68525|delta/epsilon subdivisions,2WPAQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
MMD1_k127_3670568_12	945713.IALB_1689	1.027e-25	119.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	JD73_00815	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMD1_k127_3670568_9	635013.TherJR_1090	2.979e-66	230.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,262HG@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD1_k127_3670568_7	485916.Dtox_3052	4.242e-88	301.0	COG1456@1|root,COG1456@2|Bacteria,1VTSK@1239|Firmicutes,24XXV@186801|Clostridia,263UF@186807|Peptococcaceae	186801|Clostridia	C	CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786,FeS
MMD1_k127_3670568_11	909663.KI867150_gene2870	1.849e-58	213.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria,2MRR6@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3670568_0	56780.SYN_02485	0.0	1101.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,PTS_EIIA_2
MMD1_k127_3670568_8	56780.SYN_02484	1.666e-78	271.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp1	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_3670568_1	880073.Calab_2840	4.575e-221	696.0	COG2303@1|root,COG2303@2|Bacteria,2NRUE@2323|unclassified Bacteria	2|Bacteria	E	GMC oxidoreductase	choD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
MMD1_k127_3670568_6	1304888.ATWF01000001_gene1929	2.379e-97	326.0	COG4866@1|root,COG4866@2|Bacteria,2GF8M@200930|Deferribacteres	200930|Deferribacteres	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
MMD1_k127_3670568_13	56780.SYN_00199	3.358e-17	89.0	COG3064@1|root,COG3064@2|Bacteria,1R7D3@1224|Proteobacteria,42Y44@68525|delta/epsilon subdivisions,2X6IP@28221|Deltaproteobacteria,2MRQW@213462|Syntrophobacterales	68525|delta/epsilon subdivisions	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3670568_2	706587.Desti_5611	6.545e-158	507.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2MQ8M@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism	-	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
MMD1_k127_3670568_10	1267534.KB906758_gene2498	4.975e-62	218.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
MMD1_k127_3670568_5	289376.THEYE_A1734	9.678e-101	334.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
MMD1_k127_3670568_4	398512.JQKC01000048_gene358	2.601e-111	391.0	COG2133@1|root,COG3291@1|root,COG3979@1|root,COG4733@1|root,COG5184@1|root,COG5297@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3979@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5297@2|Bacteria,1TQ2T@1239|Firmicutes,24EP0@186801|Clostridia,3WI1H@541000|Ruminococcaceae	186801|Clostridia	MU	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Paired_CXXCH_1,fn3
MMD1_k127_3671217_0	1123376.AUIU01000015_gene360	1.06e-115	380.0	COG2998@1|root,COG2998@2|Bacteria	2|Bacteria	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
MMD1_k127_3671217_1	96561.Dole_0207	4.276e-34	137.0	COG2005@1|root,COG2005@2|Bacteria,1P9SX@1224|Proteobacteria,42VIX@68525|delta/epsilon subdivisions,2WS6N@28221|Deltaproteobacteria,2MNVD@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
MMD1_k127_3671217_2	428125.CLOLEP_00053	5.165e-14	74.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3WGZU@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
MMD1_k127_3685175_3	717606.PaecuDRAFT_0852	1.373e-53	195.0	COG3832@1|root,COG3832@2|Bacteria,1U0QY@1239|Firmicutes,4IA68@91061|Bacilli,272ER@186822|Paenibacillaceae	91061|Bacilli	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3685175_0	1459636.NTE_02613	7.691e-103	339.0	COG0262@1|root,arCOG01490@2157|Archaea	2157|Archaea	H	Belongs to the dihydrofolate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMD1_k127_3685175_1	883078.HMPREF9695_02650	2.95e-100	340.0	COG0179@1|root,COG0179@2|Bacteria,1PPYQ@1224|Proteobacteria,2U1Q3@28211|Alphaproteobacteria,3K385@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
MMD1_k127_3685175_2	1459636.NTE_02613	3.068e-94	314.0	COG0262@1|root,arCOG01490@2157|Archaea	2157|Archaea	H	Belongs to the dihydrofolate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMD1_k127_3698212_13	483216.BACEGG_00755	6.835e-18	83.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,2FNJA@200643|Bacteroidia,4ANPE@815|Bacteroidaceae	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
MMD1_k127_3698212_10	439481.Aboo_0341	9.142e-35	138.0	COG1656@1|root,arCOG04290@2157|Archaea,2XXTT@28890|Euryarchaeota,3F3CD@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C
MMD1_k127_3698212_12	443143.GM18_1491	7.471e-19	98.0	COG1426@1|root,COG1426@2|Bacteria,1NN27@1224|Proteobacteria,42V2R@68525|delta/epsilon subdivisions,2WQP6@28221|Deltaproteobacteria,43V92@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
MMD1_k127_3698212_14	1123368.AUIS01000004_gene262	9.594e-15	83.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1S7EC@1236|Gammaproteobacteria,2NBW2@225057|Acidithiobacillales	225057|Acidithiobacillales	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_2,TPR_8
MMD1_k127_3698212_15	290397.Adeh_1300	3.838e-08	65.0	2CIFB@1|root,33D8S@2|Bacteria,1P50Z@1224|Proteobacteria,432X4@68525|delta/epsilon subdivisions,2WXP1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3698212_1	269799.Gmet_2683	2.704e-135	438.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
MMD1_k127_3698212_5	247490.KSU1_C0880	6.2e-114	376.0	COG0005@1|root,COG0005@2|Bacteria,2IZAA@203682|Planctomycetes	203682|Planctomycetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
MMD1_k127_3698212_11	639282.DEFDS_1085	1.341e-21	97.0	COG1923@1|root,COG1923@2|Bacteria,2GFV8@200930|Deferribacteres	200930|Deferribacteres	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
MMD1_k127_3698212_8	335543.Sfum_1920	1.309e-79	276.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2MQEE@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
MMD1_k127_3698212_6	290317.Cpha266_2160	1.769e-97	326.0	COG0861@1|root,COG0861@2|Bacteria,1FDFJ@1090|Chlorobi	1090|Chlorobi	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
MMD1_k127_3698212_2	1499967.BAYZ01000147_gene736	1.094e-131	441.0	COG0323@1|root,COG0323@2|Bacteria,2NNP7@2323|unclassified Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
MMD1_k127_3698212_3	671143.DAMO_0004	2.564e-125	417.0	COG0612@1|root,COG0612@2|Bacteria,2NPE5@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMD1_k127_3698212_0	671143.DAMO_0005	1.677e-154	500.0	COG0612@1|root,COG0612@2|Bacteria,2NP50@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
MMD1_k127_3698212_9	485916.Dtox_3176	1.558e-49	183.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,262BZ@186807|Peptococcaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
MMD1_k127_3698212_4	767817.Desgi_1857	4.113e-123	411.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,260B8@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
MMD1_k127_3698212_7	1123376.AUIU01000016_gene292	3.928e-97	321.0	COG0480@1|root,COG0480@2|Bacteria,3J0WU@40117|Nitrospirae	40117|Nitrospirae	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMD1_k127_3699832_8	330214.NIDE2975	1.937e-64	226.0	COG1045@1|root,COG1045@2|Bacteria,3J11G@40117|Nitrospirae	40117|Nitrospirae	E	Serine acetyltransferase, N-terminal	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
MMD1_k127_3699832_15	443144.GM21_1582	4.855e-06	57.0	2DDAV@1|root,2ZHC8@2|Bacteria,1P8PH@1224|Proteobacteria,433GC@68525|delta/epsilon subdivisions,2WXB5@28221|Deltaproteobacteria,43VWN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
MMD1_k127_3699832_9	350688.Clos_0464	4.327e-62	218.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,36HZE@31979|Clostridiaceae	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
MMD1_k127_3699832_7	203119.Cthe_2941	4.624e-68	238.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,3WINW@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.40,2.7.7.60	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R02921,R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
MMD1_k127_3699832_6	1144275.COCOR_01949	1.803e-72	258.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
MMD1_k127_3699832_11	289376.THEYE_A0972	7.586e-56	209.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	suhB	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
MMD1_k127_3699832_1	330214.NIDE0595	1.997e-172	560.0	COG0322@1|root,COG0322@2|Bacteria,3J0F1@40117|Nitrospirae	40117|Nitrospirae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
MMD1_k127_3699832_0	269799.Gmet_3219	6.989e-294	915.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,43U9W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
MMD1_k127_3699832_5	1167006.UWK_01552	1.265e-75	258.0	COG2197@1|root,COG2197@2|Bacteria,1N00U@1224|Proteobacteria,42U4C@68525|delta/epsilon subdivisions,2WQCS@28221|Deltaproteobacteria,2MNQ1@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMD1_k127_3699832_10	945713.IALB_2494	7.489e-62	243.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	exsG	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,GGDEF,HATPase_c,HATPase_c_2,HWE_HK,HisKA_2,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE,dCache_1
MMD1_k127_3699832_13	1304275.C41B8_15570	1.444e-21	102.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMD1_k127_3699832_14	740709.A10D4_09839	7.479e-16	87.0	COG0515@1|root,COG0515@2|Bacteria,1N75K@1224|Proteobacteria,1RZ61@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,RIO1
MMD1_k127_3699832_4	671143.DAMO_0804	6.303e-85	291.0	COG0583@1|root,COG0583@2|Bacteria,2NPS6@2323|unclassified Bacteria	2|Bacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
MMD1_k127_3699832_2	330214.NIDE0245	5.051e-141	463.0	COG0260@1|root,COG0260@2|Bacteria,3J0X7@40117|Nitrospirae	40117|Nitrospirae	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
MMD1_k127_3699832_12	177437.HRM2_49390	2.16e-44	171.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2WMCA@28221|Deltaproteobacteria,2MHV7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
MMD1_k127_3699832_3	1123376.AUIU01000018_gene44	9.154e-135	442.0	COG2204@1|root,COG2204@2|Bacteria,3J10B@40117|Nitrospirae	40117|Nitrospirae	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3704877_1	443143.GM18_2752	3.284e-96	316.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF1	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD1_k127_3704877_0	443143.GM18_2751	1.211e-183	582.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3704877_4	518766.Rmar_1186	7.099e-13	77.0	COG0170@1|root,COG0170@2|Bacteria,4PET4@976|Bacteroidetes,1FJJU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	dolichyl monophosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3704877_2	443143.GM18_2750	1.156e-75	263.0	COG0671@1|root,COG0671@2|Bacteria,1NDCB@1224|Proteobacteria,42W6H@68525|delta/epsilon subdivisions,2WREU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
MMD1_k127_3704877_3	56780.SYN_02462	2.578e-67	244.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,42S0Z@68525|delta/epsilon subdivisions,2X5KP@28221|Deltaproteobacteria,2MRDS@213462|Syntrophobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD1_k127_3707915_3	264198.Reut_A1335	4.237e-88	295.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2VJV2@28216|Betaproteobacteria,1K0P8@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	pmrIb	-	-	-	-	-	-	-	-	-	-	-	Epimerase
MMD1_k127_3707915_2	452637.Oter_1412	5.094e-111	366.0	COG0223@1|root,COG0223@2|Bacteria,46SKS@74201|Verrucomicrobia,3K7UM@414999|Opitutae	74201|Verrucomicrobia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
MMD1_k127_3707915_1	59196.RICGR_1237	8.551e-121	394.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1JGKD@118969|Legionellales	118969|Legionellales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD1_k127_3707915_0	1089439.KB902251_gene1490	1.829e-161	518.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,461RD@72273|Thiotrichales	72273|Thiotrichales	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMD1_k127_3707915_4	1121396.KB893024_gene3904	3.799e-10	61.0	COG2076@1|root,COG2076@2|Bacteria,1NAUF@1224|Proteobacteria,42XPT@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
MMD1_k127_370901_9	1303518.CCALI_00874	4.434e-07	63.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
MMD1_k127_370901_3	1131266.ARWQ01000013_gene69	1.022e-89	317.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
MMD1_k127_370901_5	589865.DaAHT2_2410	7.045e-39	159.0	COG0535@1|root,COG0535@2|Bacteria,1RADC@1224|Proteobacteria,42RDA@68525|delta/epsilon subdivisions,2WN4I@28221|Deltaproteobacteria,2MM5N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
MMD1_k127_370901_6	102232.GLO73106DRAFT_00011930	7.025e-25	116.0	COG1216@1|root,COG1216@2|Bacteria,1G0PG@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD1_k127_370901_2	316067.Geob_0670	2.179e-93	317.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
MMD1_k127_370901_0	1280664.AUIX01000015_gene2196	1.681e-151	487.0	COG0535@1|root,COG0535@2|Bacteria,1UET7@1239|Firmicutes,24F49@186801|Clostridia,4C0TW@830|Butyrivibrio	186801|Clostridia	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
MMD1_k127_370901_8	1313421.JHBV01000030_gene2228	6.397e-18	93.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
MMD1_k127_370901_1	588581.Cpap_1406	3.737e-125	409.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,249UD@186801|Clostridia	186801|Clostridia	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	-	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
MMD1_k127_370901_4	1121405.dsmv_0802	3.161e-51	184.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2WRUT@28221|Deltaproteobacteria,2MNXP@213118|Desulfobacterales	28221|Deltaproteobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMD1_k127_370901_7	755731.Clo1100_4065	4.174e-20	92.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia,36E7U@31979|Clostridiaceae	186801|Clostridia	C	Dehydrogenase E1 component	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
MMD1_k127_3711778_3	1121447.JONL01000002_gene1980	1.629e-142	460.0	COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria,42Q23@68525|delta/epsilon subdivisions,2WWQD@28221|Deltaproteobacteria,2MA31@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
MMD1_k127_3711778_11	926562.Oweho_3009	4.736e-48	185.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMD1_k127_3711778_7	537970.HCAN_0645	3.131e-92	312.0	COG0859@1|root,COG0859@2|Bacteria,1NCZT@1224|Proteobacteria,42QXE@68525|delta/epsilon subdivisions,2YRP9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMD1_k127_3711778_8	404589.Anae109_1840	3.512e-85	307.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
MMD1_k127_3711778_2	243231.GSU2888	4.308e-200	634.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42ZYI@68525|delta/epsilon subdivisions,2WVGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
MMD1_k127_3711778_0	316067.Geob_3341	2.086e-263	817.0	COG0318@1|root,COG0318@2|Bacteria,1QXPD@1224|Proteobacteria,43C59@68525|delta/epsilon subdivisions,2WRV5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
MMD1_k127_3711778_10	443143.GM18_0786	1.179e-75	276.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
MMD1_k127_3711778_1	404380.Gbem_1163	3.132e-235	733.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42MCH@68525|delta/epsilon subdivisions,2WJPZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD1_k127_3711778_4	404380.Gbem_1161	4.419e-137	440.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
MMD1_k127_3711778_6	404380.Gbem_1160	3.412e-111	374.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
MMD1_k127_3711778_9	316067.Geob_3346	4.012e-78	280.0	COG0823@1|root,COG0823@2|Bacteria,1N5WZ@1224|Proteobacteria,42U16@68525|delta/epsilon subdivisions,2WR4G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
MMD1_k127_3711778_5	316067.Geob_3739	6.37e-130	464.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
MMD1_k127_3713469_7	269799.Gmet_2185	6.067e-31	139.0	COG2010@1|root,COG4733@1|root,COG2010@2|Bacteria,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
MMD1_k127_3713469_9	483219.LILAB_34955	1.134e-17	98.0	COG1520@1|root,COG1520@2|Bacteria,1P31B@1224|Proteobacteria	1224|Proteobacteria	O	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,VWD
MMD1_k127_3713469_4	316067.Geob_3166	7.335e-85	296.0	28WYN@1|root,33TG0@2|Bacteria,1NTYC@1224|Proteobacteria,42YTU@68525|delta/epsilon subdivisions,2WU4Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	6 heme-binding sites	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3713469_0	1232410.KI421421_gene3529	0.0	1786.0	COG2067@1|root,COG2885@1|root,COG2067@2|Bacteria,COG2885@2|Bacteria,1MY5K@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
MMD1_k127_3713469_6	291985.CCSI01000003_gene292	4.254e-32	139.0	COG4719@1|root,COG4719@2|Bacteria,1R87U@1224|Proteobacteria,2U4JA@28211|Alphaproteobacteria,2K3HI@204457|Sphingomonadales	204457|Sphingomonadales	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
MMD1_k127_3713469_5	96561.Dole_3252	1.093e-38	150.0	COG4719@1|root,COG4719@2|Bacteria,1N09K@1224|Proteobacteria,42UTG@68525|delta/epsilon subdivisions,2WQR7@28221|Deltaproteobacteria,2MP1P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
MMD1_k127_3713469_1	1232410.KI421421_gene3533	0.0	1119.0	COG1361@1|root,COG4719@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4719@2|Bacteria,COG4932@2|Bacteria,1PFZK@1224|Proteobacteria,437DI@68525|delta/epsilon subdivisions,2X2JM@28221|Deltaproteobacteria,43VQS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
MMD1_k127_3713469_8	935567.JAES01000014_gene1595	8.891e-20	93.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1SYRB@1236|Gammaproteobacteria,1XA40@135614|Xanthomonadales	135614|Xanthomonadales	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
MMD1_k127_3713469_3	589865.DaAHT2_0647	7.288e-107	362.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3713469_2	1210884.HG799462_gene8038	1.128e-109	373.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2IX1S@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
MMD1_k127_3736273_4	1167006.UWK_01341	8.79e-61	212.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42N63@68525|delta/epsilon subdivisions,2WJPA@28221|Deltaproteobacteria,2MHPB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM nickel-dependent hydrogenase large subunit	mvhL	-	1.12.1.2,1.8.98.5	ko:K00436,ko:K14126	ko00680,map00680	-	R00019,R00700,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
MMD1_k127_3736273_0	926560.KE387023_gene3326	3.113e-131	426.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF5011
MMD1_k127_3736273_2	290315.Clim_0353	3.338e-89	296.0	COG0503@1|root,COG0503@2|Bacteria,1FE1Q@1090|Chlorobi	1090|Chlorobi	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
MMD1_k127_3736273_3	1125863.JAFN01000001_gene1785	1.317e-74	255.0	COG1838@1|root,COG1838@2|Bacteria,1RCSV@1224|Proteobacteria,42NRW@68525|delta/epsilon subdivisions,2X5RX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
MMD1_k127_3736273_1	1304880.JAGB01000002_gene2272	2.304e-111	370.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
MMD1_k127_3736273_5	204669.Acid345_1951	3.983e-32	127.0	COG0039@1|root,COG0039@2|Bacteria,3Y2PG@57723|Acidobacteria,2JII1@204432|Acidobacteriia	204432|Acidobacteriia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
MMD1_k127_3741533_5	351160.LRC381	2.222e-116	381.0	COG4608@1|root,arCOG00184@2157|Archaea,2Y5BH@28890|Euryarchaeota,2N9H8@224756|Methanomicrobia	224756|Methanomicrobia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iAF692.Mbar_A0472	ABC_tran,oligo_HPY
MMD1_k127_3741533_6	1121405.dsmv_2863	3.336e-115	384.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2WJ32@28221|Deltaproteobacteria,2MIH7@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
MMD1_k127_3741533_9	215803.DB30_2430	7.275e-59	213.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria,2YUQA@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
MMD1_k127_3741533_10	706434.HMPREF9429_00581	5.344e-54	197.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4H3WK@909932|Negativicutes	909932|Negativicutes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
MMD1_k127_3741533_8	330214.NIDE3737	8.241e-94	316.0	COG0115@1|root,COG0115@2|Bacteria,3J0BM@40117|Nitrospirae	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	pabC	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMD1_k127_3741533_3	234267.Acid_4959	1.269e-139	491.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y63K@57723|Acidobacteria	57723|Acidobacteria	T	ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
MMD1_k127_3741533_2	402777.KB235904_gene2846	1.302e-164	535.0	COG1012@1|root,COG1012@2|Bacteria,1G2U1@1117|Cyanobacteria,1H7XG@1150|Oscillatoriales	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.5	ko:K00128,ko:K00129	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMD1_k127_3741533_4	926692.AZYG01000096_gene1900	3.281e-118	404.0	COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,249K1@186801|Clostridia	186801|Clostridia	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
MMD1_k127_3741533_7	1123376.AUIU01000019_gene1244	1.734e-103	347.0	COG0857@1|root,COG0857@2|Bacteria	2|Bacteria	C	belongs to the CobB CobQ family	pta	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
MMD1_k127_3741533_0	795359.TOPB45_0633	3.498e-236	750.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GH97@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
MMD1_k127_3741533_13	1232410.KI421421_gene3477	8.425e-28	119.0	2CHSG@1|root,316CZ@2|Bacteria,1PXCU@1224|Proteobacteria,4308W@68525|delta/epsilon subdivisions,2WVAX@28221|Deltaproteobacteria,43V1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
MMD1_k127_3741533_11	1121918.ARWE01000001_gene827	2.447e-37	152.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria,42YES@68525|delta/epsilon subdivisions,2WU80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_3741533_14	522772.Dacet_2619	6.087e-26	113.0	2EBFT@1|root,335GE@2|Bacteria,2GGHP@200930|Deferribacteres	200930|Deferribacteres	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3741533_16	316067.Geob_1050	1.853e-09	70.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
MMD1_k127_3741533_12	56780.SYN_00794	1.132e-32	137.0	COG1502@1|root,COG1502@2|Bacteria,1RK7U@1224|Proteobacteria,42WC8@68525|delta/epsilon subdivisions,2X6NZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
MMD1_k127_3741533_1	635013.TherJR_0525	7.464e-218	683.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,260IW@186807|Peptococcaceae	186801|Clostridia	C	PFAM Acetyl-CoA hydrolase transferase	cat	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
MMD1_k127_3774989_5	1128427.KB904821_gene2857	4.538e-20	91.0	COG0662@1|root,COG0662@2|Bacteria,1G5PK@1117|Cyanobacteria,1HC1C@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD1_k127_3774989_2	316067.Geob_1896	4.192e-62	237.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_9,SpoIIE
MMD1_k127_3774989_4	243231.GSU3519	5.109e-26	110.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMD1_k127_3774989_1	639282.DEFDS_0642	8.28e-121	406.0	COG0318@1|root,COG0318@2|Bacteria,2GETC@200930|Deferribacteres	200930|Deferribacteres	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
MMD1_k127_3774989_3	926562.Oweho_3009	9.38e-48	184.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMD1_k127_3774989_0	404380.Gbem_2669	3.364e-121	419.0	COG0834@1|root,COG4191@1|root,COG4936@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,PAS_4,PocR,Response_reg,SBP_bac_3
MMD1_k127_38064_6	1304885.AUEY01000052_gene1548	9.436e-49	181.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PZ3@68525|delta/epsilon subdivisions,2WJU4@28221|Deltaproteobacteria,2MIHB@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD1_k127_38064_14	710393.HSUHS1_0927	2.648e-11	70.0	2CCD9@1|root,32NJ2@2|Bacteria,1Q3UE@1224|Proteobacteria,42XU5@68525|delta/epsilon subdivisions,2YQSW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
MMD1_k127_38064_3	316067.Geob_2520	1.362e-109	367.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2WKC5@28221|Deltaproteobacteria,43TVM@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Domain of unknown function (DUF4118)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HD,HD_5,dCache_2
MMD1_k127_38064_8	671143.DAMO_2589	2.258e-44	169.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
MMD1_k127_38064_13	1379698.RBG1_1C00001G0502	4.448e-24	113.0	COG1729@1|root,COG1729@2|Bacteria,2NQ0B@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
MMD1_k127_38064_12	909663.KI867150_gene1328	1.742e-32	134.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
MMD1_k127_38064_1	909663.KI867150_gene54	2.18e-230	730.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2MQ5N@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
MMD1_k127_38064_4	671143.DAMO_0497	9.375e-107	360.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
MMD1_k127_38064_15	1198232.CYCME_2167	5.068e-05	55.0	COG0810@1|root,COG0810@2|Bacteria,1RKRA@1224|Proteobacteria	1224|Proteobacteria	M	Cell envelope biogenesis protein TolA	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
MMD1_k127_38064_11	330214.NIDE3362	1.726e-32	135.0	COG0848@1|root,COG0848@2|Bacteria,3J0T6@40117|Nitrospirae	40117|Nitrospirae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
MMD1_k127_38064_7	671143.DAMO_0494	2.448e-45	174.0	COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
MMD1_k127_38064_2	1121468.AUBR01000023_gene2763	1.988e-223	716.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,42FES@68295|Thermoanaerobacterales	186801|Clostridia	HP	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
MMD1_k127_38064_5	309801.trd_A0056	5.059e-52	191.0	COG0243@1|root,COG0243@2|Bacteria,2G62W@200795|Chloroflexi,27Z11@189775|Thermomicrobia	189775|Thermomicrobia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4
MMD1_k127_38064_0	1128421.JAGA01000002_gene1536	0.0	1118.0	COG0243@1|root,COG0243@2|Bacteria,2NQFR@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	fdhA2	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMD1_k127_38064_10	986075.CathTA2_1826	1.371e-33	132.0	COG0437@1|root,COG0437@2|Bacteria,1TT2G@1239|Firmicutes,4HII4@91061|Bacilli	91061|Bacilli	C	4Fe-4S ferredoxin	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_7
MMD1_k127_3814854_0	382464.ABSI01000021_gene413	1.68e-161	513.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
MMD1_k127_3814854_3	1157708.KB907450_gene5819	0.0004464	51.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,4ADCG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Ankyrin	arp3	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
MMD1_k127_3814854_1	269799.Gmet_2477	3.252e-80	275.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
MMD1_k127_3814854_2	316067.Geob_1031	2.991e-32	138.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
MMD1_k127_3842281_3	555779.Dthio_PD3233	5.702e-135	458.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,43D31@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG2	-	1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3	ko:K00123,ko:K00336,ko:K05299,ko:K06441	ko00190,ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00630,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00019,R00134,R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_10,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMD1_k127_3842281_26	555779.Dthio_PD3234	3.425e-38	153.0	COG1894@1|root,COG1894@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer4,SLBB
MMD1_k127_3842281_2	555779.Dthio_PD3236	1.62e-252	793.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2M833@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00124,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
MMD1_k127_3842281_24	555779.Dthio_PD3237	2.394e-45	171.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SED@68525|delta/epsilon subdivisions,2WPP9@28221|Deltaproteobacteria,2M7XW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE-2	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
MMD1_k127_3842281_22	1313304.CALK_1132	3.168e-47	179.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
MMD1_k127_3842281_37	1313304.CALK_1130	1.763e-14	79.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	bta	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin,TraF
MMD1_k127_3842281_34	316067.Geob_2775	5.639e-16	85.0	COG0457@1|root,COG0457@2|Bacteria	316067.Geob_2775|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3842281_39	264462.Bd0672	2.366e-06	53.0	COG2010@1|root,COG2010@2|Bacteria,1QVQX@1224|Proteobacteria,43C8Z@68525|delta/epsilon subdivisions,2X7JC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Protein of unknown function (DUF1592)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD4
MMD1_k127_3842281_17	1379698.RBG1_1C00001G0657	6.339e-53	190.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	Z012_09115	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
MMD1_k127_3842281_19	861299.J421_0746	9.488e-52	188.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
MMD1_k127_3842281_31	1123258.AQXZ01000014_gene4853	7.672e-27	120.0	2A15F@1|root,30PBA@2|Bacteria,2GQAE@201174|Actinobacteria,4G823@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3842281_8	1086011.HJ01_01878	2.285e-76	268.0	COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes,1I2NR@117743|Flavobacteriia,2NVJM@237|Flavobacterium	976|Bacteroidetes	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt,AHSA1
MMD1_k127_3842281_18	1086011.HJ01_01878	2.056e-52	191.0	COG3832@1|root,COG3832@2|Bacteria,4NFVK@976|Bacteroidetes,1I2NR@117743|Flavobacteriia,2NVJM@237|Flavobacterium	976|Bacteroidetes	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt,AHSA1
MMD1_k127_3842281_15	153721.MYP_3119	4.375e-59	210.0	COG0262@1|root,COG0262@2|Bacteria,4NPX6@976|Bacteroidetes,47RPC@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
MMD1_k127_3842281_25	264462.Bd1403	2.346e-38	147.0	COG3324@1|root,COG3324@2|Bacteria,1N7Q5@1224|Proteobacteria,42Y00@68525|delta/epsilon subdivisions,2WT7X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
MMD1_k127_3842281_30	439235.Dalk_0228	5.579e-27	116.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2WNUH@28221|Deltaproteobacteria,2MJVE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	TIGRFAM thioredoxin	trx-3	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
MMD1_k127_3842281_21	555779.Dthio_PD3063	1.325e-48	179.0	COG1618@1|root,COG1618@2|Bacteria,1N4XQ@1224|Proteobacteria,430FS@68525|delta/epsilon subdivisions,2WW2Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NTPase	-	-	-	-	-	-	-	-	-	-	-	-	NTPase_1
MMD1_k127_3842281_32	224325.AF_0792	5.918e-26	111.0	COG1801@1|root,arCOG04291@2157|Archaea,2XWUT@28890|Euryarchaeota,246KF@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
MMD1_k127_3842281_12	1499967.BAYZ01000022_gene231	3.116e-66	233.0	COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD1_k127_3842281_9	56780.SYN_02040	1.407e-72	251.0	COG0177@1|root,COG0177@2|Bacteria,1N2HB@1224|Proteobacteria,430KB@68525|delta/epsilon subdivisions,2WW2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3842281_14	1227352.C173_27410	6.103e-61	219.0	COG3340@1|root,COG3340@2|Bacteria,1TRBA@1239|Firmicutes,4HB19@91061|Bacilli,26W9N@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
MMD1_k127_3842281_36	177439.DP0507	8.557e-15	84.0	2ESCQ@1|root,33JXH@2|Bacteria,1P9JE@1224|Proteobacteria,4325U@68525|delta/epsilon subdivisions,2WXM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3842281_5	404380.Gbem_2091	1.823e-112	376.0	COG5492@1|root,COG5492@2|Bacteria,1QYX0@1224|Proteobacteria	1224|Proteobacteria	N	Protein of unknown function (DUF3443)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3443
MMD1_k127_3842281_23	269799.Gmet_1675	1.887e-45	170.0	2E5QB@1|root,330EW@2|Bacteria,1N890@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2844
MMD1_k127_3842281_1	404589.Anae109_1032	1.472e-287	915.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
MMD1_k127_3842281_0	909663.KI867150_gene1866	3.628e-298	927.0	COG0773@1|root,COG1376@1|root,COG0773@2|Bacteria,COG1376@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MR03@213462|Syntrophobacterales	68525|delta/epsilon subdivisions	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP0623	Mur_ligase,Mur_ligase_C,Mur_ligase_M
MMD1_k127_3842281_20	637390.AFOH01000136_gene1793	5.995e-51	188.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,1S2JM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	NADPH-dependent F420 reductase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
MMD1_k127_3842281_13	264462.Bd3174	7.158e-63	226.0	COG0702@1|root,COG0702@2|Bacteria,1N8V3@1224|Proteobacteria,4307M@68525|delta/epsilon subdivisions,2WVDH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3842281_7	398767.Glov_3423	8.352e-77	269.0	2CJRU@1|root,2ZUZ5@2|Bacteria,1RERA@1224|Proteobacteria,42ZIF@68525|delta/epsilon subdivisions,2WV3G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3842281_40	56780.SYN_02921	0.0004352	49.0	28XYV@1|root,2ZJUR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3842281_11	290397.Adeh_0897	1.994e-67	245.0	2C0SQ@1|root,33DUT@2|Bacteria,1R7NR@1224|Proteobacteria,4319Q@68525|delta/epsilon subdivisions,2WW9H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3842281_28	1122194.AUHU01000004_gene1468	2.538e-32	132.0	COG2755@1|root,COG2755@2|Bacteria,1N7J4@1224|Proteobacteria,1S9Y7@1236|Gammaproteobacteria,46CAF@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
MMD1_k127_3842281_38	767817.Desgi_2872	4.472e-10	65.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	DUF3795,OsmC
MMD1_k127_3842281_35	243231.GSU1057	7.939e-15	81.0	COG0457@1|root,COG0457@2|Bacteria,1P22J@1224|Proteobacteria,4310H@68525|delta/epsilon subdivisions,2WWBW@28221|Deltaproteobacteria,43VHQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3842281_10	1266925.JHVX01000001_gene2515	4.719e-70	242.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,373JM@32003|Nitrosomonadales	28216|Betaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
MMD1_k127_3842281_4	316067.Geob_0942	5.023e-134	447.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria	1224|Proteobacteria	G	glucose sorbosone	gdhB	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	CBM_2,GSDH
MMD1_k127_3842281_6	526222.Desal_2833	5.52e-80	271.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MB6B@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
MMD1_k127_3842281_29	330214.NIDE3217	4.286e-30	127.0	COG1678@1|root,COG1678@2|Bacteria	2|Bacteria	K	ribonucleoside-diphosphate reductase activity	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
MMD1_k127_3842281_27	1121918.ARWE01000001_gene2221	6.203e-38	150.0	COG0589@1|root,COG0589@2|Bacteria,1Q0M5@1224|Proteobacteria,430YY@68525|delta/epsilon subdivisions,2WVQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_3842281_16	243231.GSU1442	1.047e-55	202.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,42MSW@68525|delta/epsilon subdivisions,2WNY3@28221|Deltaproteobacteria,43TY3@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
MMD1_k127_3857519_1	1045858.Bint_2124	2.344e-89	297.0	COG1274@1|root,COG1274@2|Bacteria,2J5BB@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
MMD1_k127_3857519_0	56780.SYN_02232	2.619e-104	346.0	COG1980@1|root,COG1980@2|Bacteria,1MXM7@1224|Proteobacteria,42YTY@68525|delta/epsilon subdivisions,2WTMS@28221|Deltaproteobacteria,2MRGZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Fructose-1,6-bisphosphatase	-	-	3.1.3.11,4.1.2.13	ko:K01622	ko00010,ko00030,ko00051,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00003	R00762,R01068,R01070,R02568,R04780	RC00017,RC00438,RC00439	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_3
MMD1_k127_3863684_2	883.DvMF_1984	2.707e-190	599.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42MRE@68525|delta/epsilon subdivisions,2WIP0@28221|Deltaproteobacteria,2M81I@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_3863684_18	335543.Sfum_0645	1.649e-75	269.0	2C5J8@1|root,30F9Z@2|Bacteria,1RE16@1224|Proteobacteria,42RYB@68525|delta/epsilon subdivisions,2WNIF@28221|Deltaproteobacteria,2MRTU@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3863684_37	335543.Sfum_0646	7.139e-24	106.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_3863684_25	338969.Rfer_2742	7.522e-62	233.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,2VP9Y@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
MMD1_k127_3863684_7	1379698.RBG1_1C00001G1210	5.622e-125	415.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_3863684_54	481448.Minf_2154	0.0007477	48.0	COG0589@1|root,COG0589@2|Bacteria,46WHB@74201|Verrucomicrobia,37GYA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_3863684_53	768679.TTX_0003	0.0003238	51.0	COG0589@1|root,arCOG02053@2157|Archaea,2XQTK@28889|Crenarchaeota	28889|Crenarchaeota	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_3863684_29	269799.Gmet_2428	1.255e-44	166.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,42SAC@68525|delta/epsilon subdivisions,2WP7J@28221|Deltaproteobacteria,43SMK@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver domain	cheY34H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
MMD1_k127_3863684_47	443144.GM21_2621	9.57e-11	67.0	COG1366@1|root,COG1366@2|Bacteria,1NK6S@1224|Proteobacteria,42X2N@68525|delta/epsilon subdivisions,2WSS9@28221|Deltaproteobacteria,43ST5@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
MMD1_k127_3863684_1	1304885.AUEY01000005_gene859	6.562e-235	746.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2MJ5N@213118|Desulfobacterales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric	cheA34H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
MMD1_k127_3863684_5	316067.Geob_2266	3.924e-133	442.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	mcp34H-6	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
MMD1_k127_3863684_11	269799.Gmet_2420	1.947e-98	334.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria,43SBQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR34H	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
MMD1_k127_3863684_4	443144.GM21_2616	2.35e-160	519.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria,43S6W@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB34H	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
MMD1_k127_3863684_9	330214.NIDE4314	5.341e-117	386.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3863684_23	289376.THEYE_A0660	8.748e-67	232.0	COG0279@1|root,COG0279@2|Bacteria,3J0HG@40117|Nitrospirae	40117|Nitrospirae	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
MMD1_k127_3863684_21	264732.Moth_0052	1.463e-69	244.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,42G79@68295|Thermoanaerobacterales	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
MMD1_k127_3863684_19	292459.STH2313	7.712e-72	265.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
MMD1_k127_3863684_13	1379270.AUXF01000004_gene3278	2.962e-94	320.0	COG0601@1|root,COG0601@2|Bacteria,1ZSXJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMD1_k127_3863684_44	929556.Solca_1445	4.009e-12	75.0	2ATWF@1|root,31JFP@2|Bacteria,4NQPB@976|Bacteroidetes,1ITBA@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3863684_39	1123296.JQKE01000010_gene80	2.275e-20	99.0	2E1IN@1|root,32WWF@2|Bacteria,1N37Q@1224|Proteobacteria,2VYQE@28216|Betaproteobacteria,2KT58@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3863684_17	290397.Adeh_3160	3.597e-81	277.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,42ZSX@68525|delta/epsilon subdivisions,2WV17@28221|Deltaproteobacteria,2YZ2N@29|Myxococcales	28221|Deltaproteobacteria	IQ	reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
MMD1_k127_3863684_12	398767.Glov_3024	3.726e-97	325.0	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,43CPP@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
MMD1_k127_3863684_0	671143.DAMO_1167	6.198e-236	764.0	COG2982@1|root,COG2982@2|Bacteria	2|Bacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
MMD1_k127_3863684_36	671143.DAMO_1803	5.947e-25	109.0	2EAWU@1|root,334Y1@2|Bacteria	2|Bacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
MMD1_k127_3863684_28	706587.Desti_0262	2.649e-47	177.0	COG0500@1|root,COG2226@2|Bacteria,1PEBD@1224|Proteobacteria,42T7H@68525|delta/epsilon subdivisions,2WPN7@28221|Deltaproteobacteria,2MQP2@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
MMD1_k127_3863684_50	489825.LYNGBM3L_64500	1.301e-06	51.0	COG0500@1|root,COG5126@1|root,COG2226@2|Bacteria,COG5126@2|Bacteria,1G3E7@1117|Cyanobacteria	1117|Cyanobacteria	DOTZ	signal transduction protein with EFhand domain	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_1,EF-hand_5,EF-hand_7,Evr1_Alr
MMD1_k127_3863684_52	1538295.JY96_11155	0.000238	52.0	COG0551@1|root,COG1787@1|root,COG0551@2|Bacteria,COG1787@2|Bacteria,1RAHG@1224|Proteobacteria,2VNZE@28216|Betaproteobacteria,1KKQK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Topoisomerase DNA binding C4 zinc finger	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat,zf-C4_Topoisom
MMD1_k127_3863684_31	909663.KI867150_gene65	5.218e-40	155.0	COG5663@1|root,COG5663@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K05967	-	-	-	-	ko00000	-	-	-	NT5C
MMD1_k127_3863684_6	1005048.CFU_1853	8.24e-132	435.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,473TS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
MMD1_k127_3863684_22	1040989.AWZU01000049_gene933	8.182e-69	246.0	COG3115@1|root,COG3115@2|Bacteria,1QR19@1224|Proteobacteria,2U3VA@28211|Alphaproteobacteria,3JV0B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	D	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
MMD1_k127_3863684_45	525897.Dbac_0718	9.702e-12	70.0	2E20Q@1|root,32X8P@2|Bacteria,1N3P4@1224|Proteobacteria,42TSV@68525|delta/epsilon subdivisions,2WQ7Q@28221|Deltaproteobacteria,2MCZ9@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3863684_40	1173024.KI912148_gene4772	2.976e-20	99.0	COG1357@1|root,COG1357@2|Bacteria,1G70X@1117|Cyanobacteria,1JKV5@1189|Stigonemataceae	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
MMD1_k127_3863684_42	338963.Pcar_2636	4.971e-18	87.0	COG2501@1|root,COG2501@2|Bacteria,1N7NW@1224|Proteobacteria,42W9B@68525|delta/epsilon subdivisions,2WS2I@28221|Deltaproteobacteria,43SRM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	S4 domain	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
MMD1_k127_3863684_43	243231.GSU0906	1.542e-12	72.0	COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,42XSC@68525|delta/epsilon subdivisions,2WT18@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
MMD1_k127_3863684_35	420662.Mpe_A3805	9.167e-29	118.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMD1_k127_3863684_33	1499967.BAYZ01000118_gene3297	4.428e-29	128.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
MMD1_k127_3863684_3	1125863.JAFN01000001_gene2733	8.281e-185	601.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
MMD1_k127_3863684_49	595460.RRSWK_06217	6.562e-07	60.0	2DM90@1|root,327AV@2|Bacteria,2IZ12@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
MMD1_k127_3863684_20	234267.Acid_1248	1.653e-70	248.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria	57723|Acidobacteria	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
MMD1_k127_3863684_48	1267535.KB906767_gene561	2.48e-10	61.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia	204432|Acidobacteriia	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
MMD1_k127_3863684_15	404380.Gbem_1199	1.575e-85	291.0	COG2085@1|root,COG2085@2|Bacteria,1RCXR@1224|Proteobacteria,43070@68525|delta/epsilon subdivisions,2WVFX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
MMD1_k127_3863684_30	398527.Bphyt_4937	3.401e-42	157.0	COG1359@1|root,COG1359@2|Bacteria,1N1AN@1224|Proteobacteria,2W2Q1@28216|Betaproteobacteria,1K98I@119060|Burkholderiaceae	28216|Betaproteobacteria	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3863684_41	405948.SACE_2456	1.218e-18	92.0	2DNU1@1|root,32Z4S@2|Bacteria,2I3QM@201174|Actinobacteria,4EATF@85010|Pseudonocardiales	201174|Actinobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
MMD1_k127_3863684_34	572546.Arcpr_1419	4.852e-29	119.0	COG1504@1|root,arCOG04337@2157|Archaea,2Y6F4@28890|Euryarchaeota,247CC@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
MMD1_k127_3863684_32	266117.Rxyl_2819	4.21e-32	141.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
MMD1_k127_3863684_26	1476973.JMMB01000007_gene312	8.171e-62	220.0	COG1388@1|root,COG1388@2|Bacteria,1V4FC@1239|Firmicutes,24CPD@186801|Clostridia	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
MMD1_k127_3863684_46	1968.JOEV01000048_gene3437	5.807e-11	70.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
MMD1_k127_3863684_10	880073.Calab_0995	4.92e-112	372.0	COG0501@1|root,COG0501@2|Bacteria,2NS4G@2323|unclassified Bacteria	2|Bacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
MMD1_k127_3863684_51	485915.Dret_1803	4.144e-05	52.0	COG3086@1|root,COG3086@2|Bacteria	2|Bacteria	T	response to oxidative stress	rseC	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
MMD1_k127_3863684_38	443143.GM18_0983	1.981e-23	104.0	28PU4@1|root,33ET9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3863684_27	439235.Dalk_1685	9.715e-59	208.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions,2WNNI@28221|Deltaproteobacteria,2MK5V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
MMD1_k127_3863684_24	1123376.AUIU01000015_gene362	2.916e-66	244.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	gtsA	-	3.6.3.30,3.6.3.55	ko:K02010,ko:K02049,ko:K02068,ko:K02071,ko:K06857,ko:K10112	ko02010,map02010	M00186,M00188,M00190,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00211,M00238,M00491,M00602,M00605,M00606	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.10,3.A.1.16,3.A.1.17,3.A.1.24,3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran,TOBE_2
MMD1_k127_3863684_14	289376.THEYE_A0048	1.468e-87	298.0	COG4662@1|root,COG4662@2|Bacteria,3J12J@40117|Nitrospirae	40117|Nitrospirae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
MMD1_k127_3863684_8	1123376.AUIU01000015_gene360	1.429e-119	389.0	COG2998@1|root,COG2998@2|Bacteria	2|Bacteria	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
MMD1_k127_3863684_16	370438.PTH_0603	1.385e-82	278.0	COG2998@1|root,COG2998@2|Bacteria,1VTHN@1239|Firmicutes,24YK1@186801|Clostridia,264PR@186807|Peptococcaceae	186801|Clostridia	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
MMD1_k127_3892420_12	118005.AWNK01000001_gene2130	1.272e-10	72.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
MMD1_k127_3892420_4	330214.NIDE4089	5.285e-118	388.0	COG1702@1|root,COG1702@2|Bacteria,3J0AD@40117|Nitrospirae	40117|Nitrospirae	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
MMD1_k127_3892420_6	330214.NIDE1089	5.897e-60	217.0	COG1040@1|root,COG1040@2|Bacteria,3J19P@40117|Nitrospirae	40117|Nitrospirae	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
MMD1_k127_3892420_0	443143.GM18_4206	2.602e-201	640.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,43T5X@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
MMD1_k127_3892420_5	330214.NIDE1096	2.254e-100	344.0	COG2956@1|root,COG2956@2|Bacteria,3J0KC@40117|Nitrospirae	40117|Nitrospirae	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMD1_k127_3892420_9	443143.GM18_4207	3.63e-31	129.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria,43UX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
MMD1_k127_3892420_10	997346.HMPREF9374_1431	5.272e-30	123.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli,27C1C@186824|Thermoactinomycetaceae	91061|Bacilli	J	Ribosomal silencing factor during starvation	rsfS	GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
MMD1_k127_3892420_7	1121428.DESHY_160031___1	5.436e-52	191.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,261W4@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
MMD1_k127_3892420_1	289376.THEYE_A0790	5.299e-161	519.0	COG0014@1|root,COG0014@2|Bacteria,3J0ET@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
MMD1_k127_3892420_11	1123392.AQWL01000002_gene2032	7.998e-16	85.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2VWK8@28216|Betaproteobacteria,1KT4G@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
MMD1_k127_3892420_3	316067.Geob_0607	1.428e-119	396.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
MMD1_k127_3892420_2	1123376.AUIU01000016_gene303	2.385e-130	424.0	COG0536@1|root,COG0536@2|Bacteria,3J0E3@40117|Nitrospirae	40117|Nitrospirae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
MMD1_k127_3892420_8	635013.TherJR_2529	1.694e-34	134.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,262E4@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
MMD1_k127_3902246_1	443143.GM18_3420	9.569e-182	611.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
MMD1_k127_3902246_4	1458275.AZ34_05040	1.417e-58	212.0	COG1073@1|root,COG1073@2|Bacteria,1QKK6@1224|Proteobacteria,2VNYN@28216|Betaproteobacteria,4AEY6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
MMD1_k127_3902246_3	456442.Mboo_1138	7.186e-96	321.0	COG3384@1|root,arCOG01730@2157|Archaea,2Y0BA@28890|Euryarchaeota,2NAWC@224756|Methanomicrobia	224756|Methanomicrobia	E	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
MMD1_k127_3902246_0	269799.Gmet_2768	8.415e-206	647.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
MMD1_k127_3902246_2	1232410.KI421422_gene2029	2.128e-113	374.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
MMD1_k127_3902246_5	1121441.AUCX01000014_gene497	2.072e-13	74.0	COG0457@1|root,COG0457@2|Bacteria	1121441.AUCX01000014_gene497|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3903645_2	497965.Cyan7822_3550	2.144e-79	274.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
MMD1_k127_3903645_0	762376.AXYL_00267	2.027e-252	794.0	COG2267@1|root,COG4870@1|root,COG2267@2|Bacteria,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2VN18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
MMD1_k127_3903645_4	1121015.N789_01165	3.916e-37	147.0	2ASI4@1|root,31HYJ@2|Bacteria,1QFMX@1224|Proteobacteria,1TCXF@1236|Gammaproteobacteria,1X9UV@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3903645_1	649638.Trad_2159	5.79e-83	287.0	COG1407@1|root,COG1407@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
MMD1_k127_3903645_5	1313265.JNIE01000006_gene145	5.428e-22	105.0	COG3063@1|root,COG3063@2|Bacteria,2G55J@200783|Aquificae	200783|Aquificae	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
MMD1_k127_3903645_6	204536.SULAZ_0561	5.553e-11	64.0	COG3271@1|root,COG3271@2|Bacteria,2G4YK@200783|Aquificae	200783|Aquificae	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39,Peptidase_C39_2
MMD1_k127_3906943_0	335543.Sfum_2510	2.429e-146	469.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2MR87@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2_2
MMD1_k127_3906943_1	335543.Sfum_2511	1.206e-126	413.0	COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,42RX4@68525|delta/epsilon subdivisions,2WNBJ@28221|Deltaproteobacteria,2MQZF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
MMD1_k127_3908282_14	379066.GAU_3340	2.294e-16	84.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
MMD1_k127_3908282_3	909663.KI867150_gene1470	2.316e-94	320.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42QRA@68525|delta/epsilon subdivisions,2WN1V@28221|Deltaproteobacteria,2MQMM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
MMD1_k127_3908282_5	909663.KI867150_gene1281	1.623e-87	292.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,42U2Q@68525|delta/epsilon subdivisions,2WQK9@28221|Deltaproteobacteria,2MRE5@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
MMD1_k127_3908282_4	292459.STH343	6.242e-93	310.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia	186801|Clostridia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
MMD1_k127_3908282_6	293826.Amet_1249	8.415e-69	241.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,36E0S@31979|Clostridiaceae	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941,ko:K14153	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
MMD1_k127_3908282_11	1125863.JAFN01000001_gene3501	5.346e-46	177.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,42U06@68525|delta/epsilon subdivisions,2WP2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
MMD1_k127_3908282_0	349161.Dred_2890	1.87e-176	564.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,260F0@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
MMD1_k127_3908282_7	243231.GSU0587	8.236e-57	205.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,43UPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
MMD1_k127_3908282_2	330214.NIDE3060	1.142e-125	407.0	COG2022@1|root,COG2022@2|Bacteria,3J0EI@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
MMD1_k127_3908282_16	416348.Hlac_3402	1.221e-08	61.0	arCOG10364@1|root,arCOG10364@2157|Archaea,2XZDE@28890|Euryarchaeota,23X94@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3908282_15	1382304.JNIL01000001_gene3119	2.961e-14	74.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes	1239|Firmicutes	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
MMD1_k127_3908282_13	195253.Syn6312_1865	7.752e-21	101.0	COG5661@1|root,COG5661@2|Bacteria,1G9TJ@1117|Cyanobacteria	1117|Cyanobacteria	O	Bacterial protein of unknown function (DUF922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF922
MMD1_k127_3908282_8	398767.Glov_3084	2.94e-56	202.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,42SUD@68525|delta/epsilon subdivisions,2WP5H@28221|Deltaproteobacteria,43UKX@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
MMD1_k127_3908282_12	1232410.KI421428_gene977	9.463e-41	160.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,42TXY@68525|delta/epsilon subdivisions,2WQ4J@28221|Deltaproteobacteria,43TM5@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Cobalamin-5-phosphate synthase	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
MMD1_k127_3908282_1	243231.GSU3009	9.242e-133	433.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,42M3Z@68525|delta/epsilon subdivisions,2WJIR@28221|Deltaproteobacteria,43TYS@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
MMD1_k127_3908282_9	880072.Desac_0476	1.033e-47	178.0	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,42TMF@68525|delta/epsilon subdivisions,2WQNM@28221|Deltaproteobacteria,2MQK1@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
MMD1_k127_3908282_10	234267.Acid_5452	1.732e-47	180.0	292MF@1|root,2ZQ5C@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
MMD1_k127_3939139_11	289376.THEYE_A0979	1.085e-51	186.0	COG0780@1|root,COG0780@2|Bacteria,3J0R4@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
MMD1_k127_3939139_6	443143.GM18_0273	3.459e-105	354.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43UDA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase S1 and S6, chymotrypsin Hap	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
MMD1_k127_3939139_15	404380.Gbem_3518	8.646e-18	87.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMD1_k127_3939139_7	671143.DAMO_1098	4.259e-74	260.0	COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria	2|Bacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
MMD1_k127_3939139_12	756499.Desde_3477	1.116e-34	140.0	COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia,262F6@186807|Peptococcaceae	186801|Clostridia	H	Molybdopterin-guanine dinucleotide biosynthesis	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
MMD1_k127_3939139_1	1125863.JAFN01000001_gene2915	1.112e-185	589.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
MMD1_k127_3939139_17	338963.Pcar_0013	2.105e-14	75.0	COG5336@1|root,COG5336@2|Bacteria,1Q3U8@1224|Proteobacteria,437BR@68525|delta/epsilon subdivisions,2X2H2@28221|Deltaproteobacteria,43VQW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
MMD1_k127_3939139_8	269799.Gmet_3518	3.654e-60	220.0	2EE9W@1|root,3384B@2|Bacteria,1NCE1@1224|Proteobacteria,42VUH@68525|delta/epsilon subdivisions,2WSA1@28221|Deltaproteobacteria,43V30@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Paired_CXXCH_1
MMD1_k127_3939139_3	269799.Gmet_3519	1.409e-135	435.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,43T2N@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
MMD1_k127_3939139_0	316067.Geob_1017	3.558e-191	604.0	COG4881@1|root,COG4881@2|Bacteria,1QXMX@1224|Proteobacteria,43C41@68525|delta/epsilon subdivisions,2WKYD@28221|Deltaproteobacteria,43TBN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Polysulphide reductase, NrfD	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
MMD1_k127_3939139_10	1232410.KI421424_gene1760	3.206e-55	198.0	COG2010@1|root,COG2010@2|Bacteria,1QYFZ@1224|Proteobacteria,43CC3@68525|delta/epsilon subdivisions,2WQTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3939139_4	1232410.KI421424_gene1759	9.097e-133	430.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
MMD1_k127_3939139_2	1232410.KI421424_gene1758	2.558e-164	527.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
MMD1_k127_3939139_9	1232410.KI421425_gene1568	3.676e-56	211.0	COG0484@1|root,COG0484@2|Bacteria,1NR5B@1224|Proteobacteria,42YEQ@68525|delta/epsilon subdivisions,2WTT6@28221|Deltaproteobacteria,43TYC@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3939139_5	243231.GSU1649	8.451e-106	356.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
MMD1_k127_3939139_14	443143.GM18_0922	1.605e-31	130.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
MMD1_k127_3939139_13	589924.Ferp_2107	6.899e-32	138.0	arCOG06549@1|root,arCOG06549@2157|Archaea,2Y31C@28890|Euryarchaeota,246R3@183980|Archaeoglobi	183980|Archaeoglobi	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
MMD1_k127_3939139_16	1121918.ARWE01000001_gene2806	8.81e-15	77.0	2AR6F@1|root,31GG2@2|Bacteria,1P4BK@1224|Proteobacteria,4325J@68525|delta/epsilon subdivisions,2WX7I@28221|Deltaproteobacteria,43VSD@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_3947762_2	289376.THEYE_A0365	1.165e-81	285.0	COG1559@1|root,COG1559@2|Bacteria,3J0IR@40117|Nitrospirae	40117|Nitrospirae	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
MMD1_k127_3947762_4	1304885.AUEY01000016_gene3024	3.476e-22	111.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
MMD1_k127_3947762_3	316067.Geob_3808	2.696e-46	184.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
MMD1_k127_3947762_1	1121403.AUCV01000003_gene1737	8.598e-106	352.0	COG3221@1|root,COG3221@2|Bacteria,1QJET@1224|Proteobacteria,42TZD@68525|delta/epsilon subdivisions,2WQIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphonate ABC transporter, periplasmic	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
MMD1_k127_3947762_0	1125863.JAFN01000001_gene2513	1.647e-108	366.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	pfam abc1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,RIO1
MMD1_k127_395507_0	316067.Geob_1031	3.032e-135	445.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
MMD1_k127_395507_1	404380.Gbem_1579	1.117e-62	224.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,42SHU@68525|delta/epsilon subdivisions,2WPGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
MMD1_k127_395507_2	349161.Dred_2315	2.982e-57	205.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,26062@186807|Peptococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
MMD1_k127_39559_4	497964.CfE428DRAFT_2107	1.829e-07	55.0	COG0617@1|root,COG0617@2|Bacteria,46S8B@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Poly A polymerase head domain	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
MMD1_k127_39559_3	768670.Calni_0644	2.545e-20	95.0	2DRRJ@1|root,33CRQ@2|Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_39559_0	273121.WS1178	0.0	1444.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2YMEW@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
MMD1_k127_39559_1	326298.Suden_1515	5.327e-97	324.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,42MXM@68525|delta/epsilon subdivisions,2YMAD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	TIGRFAM MauM NapG family ferredoxin-type protein	napG	-	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
MMD1_k127_39559_2	436114.SYO3AOP1_0440	1.556e-96	323.0	COG0348@1|root,COG0348@2|Bacteria,2G5CW@200783|Aquificae	200783|Aquificae	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5,Fer4_6
MMD1_k127_3992174_2	443143.GM18_2447	3.882e-31	123.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
MMD1_k127_3992174_0	1163617.SCD_n02290	1.587e-137	466.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
MMD1_k127_3992174_1	330214.NIDE0829	3.161e-61	225.0	COG5459@1|root,COG5459@2|Bacteria,3J16W@40117|Nitrospirae	40117|Nitrospirae	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
MMD1_k127_3992747_4	1121396.KB892916_gene74	1.191e-42	171.0	2CM5J@1|root,33NXS@2|Bacteria,1NHWC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_3992747_5	404380.Gbem_0338	2.625e-35	140.0	COG2133@1|root,COG2133@2|Bacteria,1PUU2@1224|Proteobacteria,433G4@68525|delta/epsilon subdivisions,2WXG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
MMD1_k127_3992747_3	1123376.AUIU01000013_gene1706	1.578e-100	334.0	COG0682@1|root,COG0682@2|Bacteria,3J0G4@40117|Nitrospirae	40117|Nitrospirae	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
MMD1_k127_3992747_2	765952.PUV_15640	2.395e-124	406.0	COG0604@1|root,COG0604@2|Bacteria	2|Bacteria	C	NADPH:quinone reductase activity	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
MMD1_k127_3992747_1	1144275.COCOR_00032	7.516e-126	412.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,42MVI@68525|delta/epsilon subdivisions,2WPP7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD1_k127_3992747_0	1123371.ATXH01000001_gene1241	1.784e-131	425.0	COG0730@1|root,COG0730@2|Bacteria,2GI6P@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_3992747_6	667014.Thein_2066	8.8e-06	57.0	2AFUA@1|root,315WQ@2|Bacteria,2GIA0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Putative transmembrane protein (Alph_Pro_TM)	-	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
MMD1_k127_4000487_0	338963.Pcar_0445	2.915e-251	781.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria,43TAF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
MMD1_k127_4000487_1	404380.Gbem_3334	6.866e-62	220.0	2CAZH@1|root,2Z7RU@2|Bacteria,1RBDC@1224|Proteobacteria,42SC7@68525|delta/epsilon subdivisions,2WP8S@28221|Deltaproteobacteria,43SJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	frdC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
MMD1_k127_4000487_2	404380.Gbem_1112	1.201e-55	213.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMD1_k127_4009828_0	568706.BN118_3388	7.806e-98	330.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,3T1RJ@506|Alcaligenaceae	28216|Betaproteobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
MMD1_k127_4009828_1	1454004.AW11_00194	3.917e-89	310.0	COG3264@1|root,COG3264@2|Bacteria,1QUDC@1224|Proteobacteria,2VJMG@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
MMD1_k127_4036888_4	441769.ABFU01000005_gene2894	3.452e-72	252.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli,1ZAXC@1386|Bacillus	91061|Bacilli	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	trmH	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
MMD1_k127_4036888_0	269799.Gmet_0057	1.82e-178	572.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,43TS3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
MMD1_k127_4036888_3	338966.Ppro_1171	2.331e-114	391.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
MMD1_k127_4036888_7	671143.DAMO_2474	2.02e-60	213.0	COG1793@1|root,COG1793@2|Bacteria,2NR3Z@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase Ligase (LigD)	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
MMD1_k127_4036888_5	1121878.AUGL01000028_gene2075	6.139e-71	247.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,1RVRF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	yiaD	-	-	ko:K12216	-	-	-	-	ko00000,ko02044	3.A.7.9.1	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
MMD1_k127_4036888_1	697282.Mettu_4039	2.631e-143	462.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,1RPQC@1236|Gammaproteobacteria,1XE7P@135618|Methylococcales	135618|Methylococcales	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
MMD1_k127_4036888_6	485913.Krac_0452	1.492e-64	231.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
MMD1_k127_4036888_2	1034943.BN1094_02225	1.035e-126	421.0	COG1372@1|root,COG1465@1|root,COG4395@1|root,COG1372@2|Bacteria,COG1465@2|Bacteria,COG4395@2|Bacteria	2|Bacteria	S	Tim44	MA20_24770	-	1.1.98.6,1.4.1.24,3.6.3.14,3.6.3.15,4.1.1.35,4.1.99.20	ko:K02117,ko:K08678,ko:K11646,ko:K15539,ko:K17835,ko:K21636	ko00190,ko00230,ko00240,ko00400,ko00520,ko01100,ko01110,ko01130,map00190,map00230,map00240,map00400,map00520,map01100,map01110,map01130	M00053,M00159,M00361	R01384,R08569,R11633,R11634,R11635,R11636	RC00508,RC00613,RC02302	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	DHQS,Tim44
MMD1_k127_4040478_4	326427.Cagg_1039	4.474e-09	59.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi,375TW@32061|Chloroflexia	32061|Chloroflexia	F	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMD1_k127_4040478_3	330214.NIDE0606	1.029e-32	136.0	COG0839@1|root,COG0839@2|Bacteria,3J0RP@40117|Nitrospirae	40117|Nitrospirae	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
MMD1_k127_4040478_2	667014.Thein_1630	1.531e-37	147.0	COG1143@1|root,COG1143@2|Bacteria,2GHHC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
MMD1_k127_4040478_1	330214.NIDE0608	1.408e-98	333.0	COG1005@1|root,COG1005@2|Bacteria,3J0E2@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
MMD1_k127_4040478_0	880072.Desac_1071	1.19e-101	351.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
MMD1_k127_4042803_0	485916.Dtox_2613	4.299e-91	304.0	COG1201@1|root,COG1201@2|Bacteria,1UHYQ@1239|Firmicutes,25E79@186801|Clostridia	186801|Clostridia	L	DEAD DEAH box helicase	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
MMD1_k127_4042803_1	316067.Geob_2058	2.712e-85	293.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
MMD1_k127_4042803_2	247490.KSU1_C0834	2.573e-52	197.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	KNTase_C,NTP_transf_2
MMD1_k127_4042803_3	1262914.BN533_01102	2.141e-06	53.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4H1Z7@909932|Negativicutes	909932|Negativicutes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
MMD1_k127_4086276_1	338963.Pcar_1691	6.887e-64	224.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,43U3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
MMD1_k127_4086276_2	171693.BN988_01224	2.518e-07	64.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,4HBCA@91061|Bacilli,23JMM@182709|Oceanobacillus	91061|Bacilli	S	AAA domain	yhaN	-	-	-	-	-	-	-	-	-	-	-	AAA_27
MMD1_k127_4086276_3	1348663.KCH_53610	0.0003713	50.0	COG0654@1|root,COG0654@2|Bacteria,2GKIN@201174|Actinobacteria,2M1B9@2063|Kitasatospora	201174|Actinobacteria	CH	FAD binding domain	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
MMD1_k127_4086276_0	635013.TherJR_2970	2.655e-106	350.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,26020@186807|Peptococcaceae	186801|Clostridia	EH	Anthranilate synthase component I	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
MMD1_k127_413957_1	880072.Desac_1359	9.208e-117	385.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2MQBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMD1_k127_413957_0	880072.Desac_2878	2.059e-126	410.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMD1_k127_413957_2	439235.Dalk_4490	3.906e-29	124.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
MMD1_k127_4178955_2	880072.Desac_0514	1.265e-74	266.0	COG0861@1|root,COG0861@2|Bacteria,1QZU6@1224|Proteobacteria,42S1Q@68525|delta/epsilon subdivisions,2WNNS@28221|Deltaproteobacteria,2MQEU@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
MMD1_k127_4178955_0	706587.Desti_1123	7.152e-212	669.0	COG2855@1|root,COG2855@2|Bacteria,1MVPE@1224|Proteobacteria,42NT6@68525|delta/epsilon subdivisions,2WJ9R@28221|Deltaproteobacteria,2MR46@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
MMD1_k127_4178955_3	243233.MCA0433	3.882e-06	58.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	wapA	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	AhpC-TSA,NHL,RHS_repeat,Thioredoxin_8
MMD1_k127_4178955_1	316067.Geob_1241	5.66e-145	470.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
MMD1_k127_4264578_3	357808.RoseRS_2986	4.209e-08	66.0	COG3391@1|root,COG3391@2|Bacteria,2GBRT@200795|Chloroflexi,376BG@32061|Chloroflexia	32061|Chloroflexia	S	PA14	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PA14
MMD1_k127_4264578_1	211165.AJLN01000097_gene5066	6.007e-161	519.0	COG0477@1|root,COG2814@2|Bacteria,1G1K4@1117|Cyanobacteria,1JJV3@1189|Stigonemataceae	1117|Cyanobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
MMD1_k127_4264578_2	1458275.AZ34_08280	6.66e-10	66.0	COG1729@1|root,COG1729@2|Bacteria,1P69R@1224|Proteobacteria,2W622@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4264578_0	580332.Slit_0253	2.471e-192	647.0	COG0457@1|root,COG1305@1|root,COG3391@1|root,COG4733@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,1R42S@1224|Proteobacteria	1224|Proteobacteria	E	fibronectin type III domain protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	-
MMD1_k127_426462_0	330214.NIDE3263	1.216e-229	726.0	COG0317@1|root,COG0317@2|Bacteria,3J0CX@40117|Nitrospirae	40117|Nitrospirae	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
MMD1_k127_426462_2	264732.Moth_1495	2.511e-45	167.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,42GJ3@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
MMD1_k127_426462_1	909663.KI867150_gene2631	7.373e-84	285.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QXM@68525|delta/epsilon subdivisions,2WMZI@28221|Deltaproteobacteria,2MRM3@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
MMD1_k127_4288882_1	608506.COB47_0274	8.314e-64	229.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,42EPT@68295|Thermoanaerobacterales	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
MMD1_k127_4288882_0	1232410.KI421413_gene827	3.078e-147	477.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43S50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
MMD1_k127_430270_1	1196322.A370_05530	6.472e-101	339.0	COG0463@1|root,COG0463@2|Bacteria,1VGSV@1239|Firmicutes	1239|Firmicutes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD1_k127_430270_4	1348908.KI518582_gene2393	5.805e-22	107.0	COG2246@1|root,COG2246@2|Bacteria,1VJZ2@1239|Firmicutes	1239|Firmicutes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
MMD1_k127_430270_0	1121875.KB907551_gene1098	1.316e-232	732.0	COG1208@1|root,COG1208@2|Bacteria,4PM3W@976|Bacteroidetes,1HYFV@117743|Flavobacteriia	976|Bacteroidetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
MMD1_k127_430270_2	866895.HBHAL_1981	7.448e-75	264.0	COG3347@1|root,COG3347@2|Bacteria,1UZ1Q@1239|Firmicutes	1239|Firmicutes	IQ	Class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
MMD1_k127_430270_3	866895.HBHAL_1980	7.661e-28	115.0	COG0546@1|root,COG0546@2|Bacteria,1UI4N@1239|Firmicutes,4ISD8@91061|Bacilli,3NERG@45667|Halobacillus	91061|Bacilli	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
MMD1_k127_4323933_8	1232410.KI421428_gene1230	2.561e-09	58.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,43S44@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein L3	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
MMD1_k127_4323933_3	879308.HMPREF9130_0670	3.006e-60	214.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,22GGG@1570339|Peptoniphilaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
MMD1_k127_4323933_6	644282.Deba_2936	2.48e-28	119.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
MMD1_k127_4323933_0	1382304.JNIL01000001_gene1962	2.952e-120	391.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli,27830@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
MMD1_k127_4323933_4	234267.Acid_5114	9.115e-38	147.0	COG0185@1|root,COG0185@2|Bacteria,3Y560@57723|Acidobacteria	57723|Acidobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
MMD1_k127_4323933_5	35841.BT1A1_0124	1.688e-29	121.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,1ZG6U@1386|Bacillus	91061|Bacilli	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
MMD1_k127_4323933_1	443143.GM18_0838	4.559e-99	327.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,43T5Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
MMD1_k127_4323933_2	330214.NIDE1318	6.904e-65	224.0	COG0197@1|root,COG0197@2|Bacteria,3J0H7@40117|Nitrospirae	40117|Nitrospirae	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
MMD1_k127_4323933_7	1160721.RBI_I01936	5.958e-14	74.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
MMD1_k127_4329662_3	545264.KB898744_gene1964	3.337e-28	117.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cytochrome_CBB3
MMD1_k127_4329662_1	589865.DaAHT2_0147	6.953e-72	253.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,42YY5@68525|delta/epsilon subdivisions,2WPYC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMD1_k127_4329662_0	398767.Glov_3521	1.516e-127	422.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K02481,ko:K11384	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_4329662_2	443144.GM21_0949	2.922e-69	247.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42YX4@68525|delta/epsilon subdivisions,2WU7X@28221|Deltaproteobacteria	1224|Proteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,HBM,MCPsignal
MMD1_k127_4369602_7	1123368.AUIS01000004_gene209	1.816e-59	211.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,1RY44@1236|Gammaproteobacteria,2NC99@225057|Acidithiobacillales	225057|Acidithiobacillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD1_k127_4369602_0	909663.KI867151_gene3153	1.302e-186	593.0	COG1379@1|root,COG1379@2|Bacteria,1QYWZ@1224|Proteobacteria,43CDU@68525|delta/epsilon subdivisions,2X7PS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4369602_2	1255043.TVNIR_3349	1.162e-104	352.0	COG1085@1|root,COG1085@2|Bacteria,1N3RW@1224|Proteobacteria	1224|Proteobacteria	C	galactose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4369602_8	913865.DOT_6248	2.379e-56	200.0	COG5561@1|root,COG5561@2|Bacteria,1VJ0D@1239|Firmicutes,24RTC@186801|Clostridia,265JS@186807|Peptococcaceae	186801|Clostridia	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
MMD1_k127_4369602_6	580332.Slit_1776	3.048e-72	259.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	Bac_surface_Ag
MMD1_k127_4369602_5	395494.Galf_0920	6.919e-86	300.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,44VG5@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMD1_k127_4369602_9	443143.GM18_1976	1.217e-05	55.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
MMD1_k127_4369602_3	247490.KSU1_C0449	2.128e-98	345.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF4347,Peptidase_S8
MMD1_k127_4369602_1	1218074.BAXZ01000025_gene4502	3.602e-109	369.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,2VK6H@28216|Betaproteobacteria,1K0YK@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
MMD1_k127_4369602_10	926549.KI421517_gene426	1.668e-05	54.0	2E4RV@1|root,32ZKD@2|Bacteria,4NWUE@976|Bacteroidetes,47W7C@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4369602_4	666685.R2APBS1_0246	1.015e-90	300.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,1S2TQ@1236|Gammaproteobacteria,1X4M1@135614|Xanthomonadales	135614|Xanthomonadales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
MMD1_k127_4380408_0	555079.Toce_1201	1.648e-114	384.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
MMD1_k127_4405131_2	1120963.KB894492_gene1741	1.427e-27	121.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RQWX@1236|Gammaproteobacteria,2Q1P9@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
MMD1_k127_4405131_1	525904.Tter_0471	1.141e-110	377.0	COG0578@1|root,COG0578@2|Bacteria,2NP90@2323|unclassified Bacteria	2|Bacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	iJN678.glpD	DAO,DAO_C
MMD1_k127_4405131_0	330214.NIDE4115	6.556e-175	556.0	COG0436@1|root,COG0436@2|Bacteria,3J0ED@40117|Nitrospirae	40117|Nitrospirae	E	Aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD1_k127_4407615_0	706587.Desti_4490	2.667e-82	276.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WMED@28221|Deltaproteobacteria,2MQU6@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
MMD1_k127_4407615_2	526222.Desal_1052	9.255e-05	51.0	COG0607@1|root,COG0607@2|Bacteria,1Q04H@1224|Proteobacteria,436CR@68525|delta/epsilon subdivisions,2X0XU@28221|Deltaproteobacteria,2MDQU@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4407615_3	1267535.KB906767_gene561	0.000158	44.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,3Y3N9@57723|Acidobacteria,2JHWT@204432|Acidobacteriia	204432|Acidobacteriia	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
MMD1_k127_4407859_3	1232410.KI421425_gene1525	6.308e-12	70.0	COG2018@1|root,COG2018@2|Bacteria,1N5TV@1224|Proteobacteria,42UGD@68525|delta/epsilon subdivisions,2WQXP@28221|Deltaproteobacteria,43SPK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
MMD1_k127_4407859_1	269799.Gmet_2369	4.79e-51	194.0	COG0671@1|root,COG0818@1|root,COG0671@2|Bacteria,COG0818@2|Bacteria,1Q5TS@1224|Proteobacteria,42SZA@68525|delta/epsilon subdivisions,2WPDT@28221|Deltaproteobacteria,43T24@69541|Desulfuromonadales	28221|Deltaproteobacteria	IM	Prokaryotic diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2369	DAGK_prokar,PAP2
MMD1_k127_4407859_2	1121396.KB893101_gene488	2.659e-24	108.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,42W3M@68525|delta/epsilon subdivisions,2WP9C@28221|Deltaproteobacteria,2MK7D@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
MMD1_k127_4407859_0	1232410.KI421413_gene704	3.539e-117	388.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,43SCT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	7TM-HD extracellular	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
MMD1_k127_4412939_0	330214.NIDE2055	3.56e-122	409.0	COG0815@1|root,COG0815@2|Bacteria,3J0HA@40117|Nitrospirae	40117|Nitrospirae	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
MMD1_k127_4412939_1	857087.Metme_2845	1.531e-06	56.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1XFJK@135618|Methylococcales	135618|Methylococcales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
MMD1_k127_4419333_4	1265505.ATUG01000002_gene1588	1.516e-47	175.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria,2MN2H@213118|Desulfobacterales	28221|Deltaproteobacteria	E	AIR synthase related protein, N-terminal domain	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
MMD1_k127_4419333_5	289376.THEYE_A0283	2.087e-43	162.0	COG2149@1|root,COG2149@2|Bacteria	2|Bacteria	S	membrane	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
MMD1_k127_4419333_3	1123376.AUIU01000011_gene1039	2.056e-52	191.0	COG2095@1|root,COG2095@2|Bacteria,3J0UZ@40117|Nitrospirae	40117|Nitrospirae	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
MMD1_k127_4419333_6	243231.GSU2724	1.681e-17	93.0	2DVSV@1|root,33X1K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4419333_0	404380.Gbem_3372	2.763e-91	321.0	2EUXR@1|root,33ND1@2|Bacteria,1P0HH@1224|Proteobacteria,431FA@68525|delta/epsilon subdivisions,2WWMS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4419333_1	1232410.KI421415_gene2936	8.314e-69	239.0	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,42SJF@68525|delta/epsilon subdivisions,2WP4X@28221|Deltaproteobacteria,43U8B@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD1_k127_4435465_64	1232410.KI421413_gene590	7.204e-34	130.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,43TCN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	GTP-binding protein LepA C-terminus	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
MMD1_k127_4435465_51	177437.HRM2_27790	2.326e-59	214.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2MIAI@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
MMD1_k127_4435465_46	867903.ThesuDRAFT_00342	2.528e-66	237.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WCKI@538999|Clostridiales incertae sedis	186801|Clostridia	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
MMD1_k127_4435465_50	269799.Gmet_2327	2.874e-61	218.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,43SG2@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
MMD1_k127_4435465_89	289376.THEYE_A0403	8.623e-07	56.0	COG1758@1|root,COG1758@2|Bacteria,3J0UJ@40117|Nitrospirae	40117|Nitrospirae	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
MMD1_k127_4435465_20	935948.KE386495_gene1769	4.623e-118	392.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,42FF1@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
MMD1_k127_4435465_81	330214.NIDE2465	6.955e-17	94.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	2.7.11.1	ko:K14949,ko:K20543	ko05152,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	1.B.55.3	-	-	DUF560,EcsC,Glyco_transf_41,HyaE,NfrA_C,Sulfotransfer_3,TPR_16
MMD1_k127_4435465_74	243231.GSU2023	1.15e-25	112.0	COG2018@1|root,COG2018@2|Bacteria,1NG1T@1224|Proteobacteria,42VP4@68525|delta/epsilon subdivisions,2WS9A@28221|Deltaproteobacteria,43V7Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4435465_54	1121428.DESHY_60070___1	2.606e-55	200.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,2621A@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
MMD1_k127_4435465_34	644966.Tmar_1187	3.691e-89	314.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WD7A@538999|Clostridiales incertae sedis	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMD1_k127_4435465_39	1162668.LFE_0957	4.853e-81	273.0	COG0231@1|root,COG0231@2|Bacteria,3J0JC@40117|Nitrospirae	40117|Nitrospirae	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
MMD1_k127_4435465_56	913865.DOT_5441	7.763e-45	169.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,260JY@186807|Peptococcaceae	186801|Clostridia	CI	Acetyl-CoA carboxylase, biotin carboxyl carrier protein	pycB	-	4.1.1.3,6.4.1.1	ko:K01571,ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00217,R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000,ko02000	3.B.1.1.1	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
MMD1_k127_4435465_7	330214.NIDE2469	1.018e-190	604.0	COG0439@1|root,COG0439@2|Bacteria,3J0AJ@40117|Nitrospirae	40117|Nitrospirae	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
MMD1_k127_4435465_55	1121430.JMLG01000025_gene95	5.419e-48	181.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,261I7@186807|Peptococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
MMD1_k127_4435465_23	671143.DAMO_1398	8.327e-114	378.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livK	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iECNA114_1301.ECNA114_3569,iECSF_1327.ECSF_3279,iECs_1301.ECs4309,iEcSMS35_1347.EcSMS35_3743,iG2583_1286.G2583_4163,iSFxv_1172.SFxv_3794,iSSON_1240.SSON_3698,iS_1188.S4285,iUTI89_1310.UTI89_C3965,iYL1228.KPN_03820,iZ_1308.Z4834	Peripla_BP_6
MMD1_k127_4435465_27	671143.DAMO_1397	4.275e-109	360.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iJN746.PP_4866,iSFV_1184.SFV_3460,iSF_1195.SF3475,iSFxv_1172.SFxv_3791,iS_1188.S4288	BPD_transp_2
MMD1_k127_4435465_8	589865.DaAHT2_1420	1.405e-190	603.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2MI2I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
MMD1_k127_4435465_83	237368.SCABRO_01825	5.954e-12	74.0	COG1283@1|root,COG1283@2|Bacteria	2|Bacteria	P	sodium-dependent phosphate transmembrane transporter activity	nptA	-	-	ko:K14683	-	-	-	-	ko00000,ko02000,ko04147	2.A.58.1	-	-	Na_Pi_cotrans
MMD1_k127_4435465_18	316067.Geob_3043	1.933e-124	411.0	COG2239@1|root,COG2239@2|Bacteria,1RFCV@1224|Proteobacteria,42S1B@68525|delta/epsilon subdivisions,2WP0D@28221|Deltaproteobacteria,43VZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
MMD1_k127_4435465_16	351627.Csac_1223	9.399e-141	458.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,24ACU@186801|Clostridia,42F5H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
MMD1_k127_4435465_32	667014.Thein_2200	3.225e-95	319.0	COG0603@1|root,COG0603@2|Bacteria,2GHPZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
MMD1_k127_4435465_90	1121422.AUMW01000022_gene1563	4.404e-06	50.0	COG1149@1|root,COG1149@2|Bacteria,1VUEG@1239|Firmicutes,2503A@186801|Clostridia,267CF@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_21,Fer4_6
MMD1_k127_4435465_78	247490.KSU1_C1594	4.181e-18	87.0	2A5W3@1|root,30UMY@2|Bacteria,2J4MS@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF1858)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
MMD1_k127_4435465_80	237368.SCABRO_03569	1.032e-17	88.0	29WUZ@1|root,30IGG@2|Bacteria,2J4C2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4435465_53	1123376.AUIU01000013_gene1711	4.873e-56	204.0	COG0664@1|root,COG0664@2|Bacteria,3J18E@40117|Nitrospirae	40117|Nitrospirae	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
MMD1_k127_4435465_59	289376.THEYE_A0569	7.344e-42	156.0	COG0720@1|root,COG0720@2|Bacteria,3J0TW@40117|Nitrospirae	40117|Nitrospirae	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
MMD1_k127_4435465_25	1121468.AUBR01000002_gene684	1.737e-112	379.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,42EMU@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
MMD1_k127_4435465_9	56780.SYN_01762	1.582e-177	572.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2MQ6V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
MMD1_k127_4435465_79	1047013.AQSP01000111_gene1661	8.824e-18	90.0	COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria	2|Bacteria	O	peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
MMD1_k127_4435465_82	123214.PERMA_1951	3.966e-16	86.0	COG0457@1|root,COG0457@2|Bacteria	123214.PERMA_1951|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4435465_33	880072.Desac_0948	2.086e-89	306.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,43AFG@68525|delta/epsilon subdivisions,2WKA9@28221|Deltaproteobacteria,2MQMK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM glycosyl transferase, family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMD1_k127_4435465_69	404589.Anae109_1886	1.051e-28	118.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42TK0@68525|delta/epsilon subdivisions,2WQ5D@28221|Deltaproteobacteria,2YVCZ@29|Myxococcales	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
MMD1_k127_4435465_71	289376.THEYE_A1235	8.755e-27	113.0	COG0789@1|root,COG0789@2|Bacteria,3J0VF@40117|Nitrospirae	40117|Nitrospirae	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
MMD1_k127_4435465_91	204669.Acid345_3963	0.00025	45.0	COG1961@1|root,COG1961@2|Bacteria,3Y3F6@57723|Acidobacteria,2JKJ1@204432|Acidobacteriia	204432|Acidobacteriia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
MMD1_k127_4435465_36	338966.Ppro_2737	6.937e-85	290.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,43T33@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
MMD1_k127_4435465_40	1123371.ATXH01000005_gene2046	3.025e-78	266.0	COG2518@1|root,COG2518@2|Bacteria,2GH2E@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
MMD1_k127_4435465_70	290397.Adeh_3940	1.142e-27	121.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
MMD1_k127_4435465_77	1120950.KB892768_gene5294	1.686e-21	99.0	COG1993@1|root,COG1993@2|Bacteria,2IM7J@201174|Actinobacteria,4DV1W@85009|Propionibacteriales	201174|Actinobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
MMD1_k127_4435465_65	1487923.DP73_14005	1.262e-32	135.0	COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,24QSV@186801|Clostridia,262VX@186807|Peptococcaceae	186801|Clostridia	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
MMD1_k127_4435465_75	1121918.ARWE01000001_gene2039	3.9e-23	109.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2WR93@28221|Deltaproteobacteria,43SS6@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
MMD1_k127_4435465_13	697281.Mahau_1153	4.661e-161	518.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,42FFC@68295|Thermoanaerobacterales	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,RnfC_N,SLBB
MMD1_k127_4435465_28	431943.CKL_1265	7.044e-104	348.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,36FI0@31979|Clostridiaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
MMD1_k127_4435465_68	927704.SELR_03820	9.651e-31	129.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,4H4F7@909932|Negativicutes	909932|Negativicutes	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
MMD1_k127_4435465_49	706587.Desti_2905	2.953e-63	223.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,42NVB@68525|delta/epsilon subdivisions,2WK6R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
MMD1_k127_4435465_44	706587.Desti_2906	1.961e-68	238.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,42MCM@68525|delta/epsilon subdivisions,2WKRE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
MMD1_k127_4435465_31	1121289.JHVL01000002_gene2427	1.208e-99	337.0	COG1142@1|root,COG2878@1|root,COG1142@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,36FC4@31979|Clostridiaceae	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
MMD1_k127_4435465_58	1123376.AUIU01000014_gene631	8.407e-43	160.0	COG0509@1|root,COG0509@2|Bacteria,3J0SD@40117|Nitrospirae	40117|Nitrospirae	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
MMD1_k127_4435465_15	330214.NIDE2727	1.422e-148	484.0	COG1249@1|root,COG1249@2|Bacteria,3J0IM@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMD1_k127_4435465_37	1121335.Clst_0243	9.518e-85	288.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,3WHY1@541000|Ruminococcaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
MMD1_k127_4435465_84	644282.Deba_2665	4.78e-10	66.0	2ENBB@1|root,32JZD@2|Bacteria,1NN3C@1224|Proteobacteria,42XM1@68525|delta/epsilon subdivisions,2WTC3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4435465_11	443144.GM21_2333	1.132e-170	569.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
MMD1_k127_4435465_47	1499967.BAYZ01000187_gene3866	2.54e-65	256.0	COG2911@1|root,COG2911@2|Bacteria,2NQ89@2323|unclassified Bacteria	2|Bacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA_2,DUF748,TamB
MMD1_k127_4435465_1	1232410.KI421418_gene2160	6.66e-308	968.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43RY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase A domain	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
MMD1_k127_4435465_86	1123288.SOV_1c09420	1.294e-08	60.0	2DNY2@1|root,32ZR4@2|Bacteria,1VEGZ@1239|Firmicutes,4H5J7@909932|Negativicutes	909932|Negativicutes	S	Late competence development protein ComFB	-	-	-	ko:K02241	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComFB
MMD1_k127_4435465_43	338969.Rfer_0258	6.359e-70	249.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,2WEWP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD1_k127_4435465_48	1158338.JNLJ01000001_gene939	3.546e-64	244.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_4435465_66	1158338.JNLJ01000005_gene1576	1.59e-32	133.0	COG0558@1|root,COG0558@2|Bacteria,2G47K@200783|Aquificae	200783|Aquificae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMD1_k127_4435465_22	1121430.JMLG01000010_gene201	7.978e-114	381.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,260YG@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512,PDZ
MMD1_k127_4435465_38	696281.Desru_3117	8.209e-83	285.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
MMD1_k127_4435465_4	706587.Desti_3124	3.658e-202	646.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2MQ93@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
MMD1_k127_4435465_10	1278073.MYSTI_06380	4.131e-172	546.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YWXD@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
MMD1_k127_4435465_21	502025.Hoch_4826	2.591e-115	383.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2YU38@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
MMD1_k127_4435465_26	1499967.BAYZ01000027_gene1787	7.058e-111	378.0	COG5000@1|root,COG5000@2|Bacteria,2NP6K@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
MMD1_k127_4435465_12	330214.NIDE0779	3.07e-168	541.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_4435465_5	574087.Acear_0505	6.085e-202	639.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,3WB84@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
MMD1_k127_4435465_29	269799.Gmet_1153	3.503e-103	351.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,43S28@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
MMD1_k127_4435465_19	316067.Geob_3487	8.271e-119	391.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,43UB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
MMD1_k127_4435465_6	429009.Adeg_1647	2.432e-194	617.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
MMD1_k127_4435465_24	330214.NIDE2052	1.96e-113	379.0	COG4591@1|root,COG4591@2|Bacteria,3J0EF@40117|Nitrospirae	40117|Nitrospirae	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
MMD1_k127_4435465_41	330214.NIDE2051	1.914e-76	266.0	COG1136@1|root,COG1136@2|Bacteria,3J0IT@40117|Nitrospirae	40117|Nitrospirae	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
MMD1_k127_4435465_57	751945.Theos_1098	7.085e-43	168.0	COG2264@1|root,COG2264@2|Bacteria,1WJ0S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
MMD1_k127_4435465_61	1158338.JNLJ01000001_gene951	5.845e-40	156.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_4435465_72	522772.Dacet_2619	1.101e-26	116.0	2EBFT@1|root,335GE@2|Bacteria,2GGHP@200930|Deferribacteres	200930|Deferribacteres	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4435465_88	443144.GM21_3540	1.139e-07	64.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
MMD1_k127_4435465_62	429009.Adeg_1666	4.145e-35	141.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,42GU2@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
MMD1_k127_4435465_17	330214.NIDE4134	1.211e-126	426.0	COG0195@1|root,COG0195@2|Bacteria,3J0DF@40117|Nitrospirae	40117|Nitrospirae	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
MMD1_k127_4435465_76	243231.GSU1587	3.361e-22	104.0	COG1358@1|root,COG2740@1|root,COG1358@2|Bacteria,COG2740@2|Bacteria,1RHPR@1224|Proteobacteria,42XP3@68525|delta/epsilon subdivisions,2WT0X@28221|Deltaproteobacteria,43UWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	JK	ribosomal protein L7Ae L30e S12e Gadd45	ylxRQ	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448,Ribosomal_L7Ae
MMD1_k127_4435465_3	269799.Gmet_1586	6.364e-248	791.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,43UH5@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
MMD1_k127_4435465_73	1379698.RBG1_1C00001G1154	3.018e-26	112.0	COG1550@1|root,COG1550@2|Bacteria,2NPYX@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF503)	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
MMD1_k127_4435465_63	373903.Hore_07850	5.032e-35	138.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3WAT9@53433|Halanaerobiales	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
MMD1_k127_4435465_42	1232410.KI421413_gene520	1.983e-75	266.0	COG0618@1|root,COG0618@2|Bacteria,1RAUQ@1224|Proteobacteria,42RKG@68525|delta/epsilon subdivisions,2WN0X@28221|Deltaproteobacteria,43TAU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
MMD1_k127_4435465_45	1499967.BAYZ01000080_gene916	1.966e-68	243.0	COG0130@1|root,COG0130@2|Bacteria,2NP9J@2323|unclassified Bacteria	2|Bacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
MMD1_k127_4435465_67	857293.CAAU_1455	1.575e-31	124.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,36KHC@31979|Clostridiaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
MMD1_k127_4435465_2	1131269.AQVV01000001_gene1389	3.439e-248	784.0	COG1185@1|root,COG1185@2|Bacteria	2|Bacteria	J	polyribonucleotide nucleotidyltransferase activity	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
MMD1_k127_4435465_87	316274.Haur_1711	5.297e-08	65.0	COG1233@1|root,COG1233@2|Bacteria,2G5U1@200795|Chloroflexi,376KH@32061|Chloroflexia	32061|Chloroflexia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMD1_k127_4435465_0	330214.NIDE2457	0.0	1136.0	COG0542@1|root,COG0542@2|Bacteria,3J0B4@40117|Nitrospirae	40117|Nitrospirae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMD1_k127_4435465_52	648996.Theam_1006	5.879e-57	202.0	COG1246@1|root,COG1246@2|Bacteria,2G3YS@200783|Aquificae	200783|Aquificae	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
MMD1_k127_4435465_35	760568.Desku_2664	1.059e-88	306.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,260TE@186807|Peptococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
MMD1_k127_4435465_14	289376.THEYE_A0094	2.552e-160	534.0	COG4775@1|root,COG4775@2|Bacteria,3J0AC@40117|Nitrospirae	40117|Nitrospirae	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
MMD1_k127_4435465_85	1232410.KI421414_gene2838	7.829e-09	64.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,43SMD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
MMD1_k127_4435465_30	330214.NIDE2646	5.207e-100	337.0	COG1044@1|root,COG1044@2|Bacteria,3J0GQ@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
MMD1_k127_4435465_60	861299.J421_3221	2.247e-41	153.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
MMD1_k127_4456347_4	1453503.AU05_25050	2.021e-82	284.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,1S0HM@1236|Gammaproteobacteria,1YCY1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
MMD1_k127_4456347_5	1441629.PCH70_14130	3.651e-09	59.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aldo keto	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,TAT_signal
MMD1_k127_4456347_1	269799.Gmet_0911	4.773e-121	400.0	2B8GB@1|root,321RF@2|Bacteria,1RIVE@1224|Proteobacteria,42SWQ@68525|delta/epsilon subdivisions,2WPWX@28221|Deltaproteobacteria,43V4P@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4456347_2	269799.Gmet_0909	1.808e-105	350.0	COG3303@1|root,COG3303@2|Bacteria,1MYBV@1224|Proteobacteria,42SER@68525|delta/epsilon subdivisions,2WPC2@28221|Deltaproteobacteria,43UYR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
MMD1_k127_4456347_0	269799.Gmet_0910	7.243e-215	689.0	COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,42VEM@68525|delta/epsilon subdivisions,2WRGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4456347_3	1125863.JAFN01000001_gene2582	3.38e-102	338.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
MMD1_k127_4461532_2	237368.SCABRO_01058	8.377e-25	106.0	COG0346@1|root,COG0346@2|Bacteria,2IZ0U@203682|Planctomycetes	203682|Planctomycetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
MMD1_k127_4461532_0	472759.Nhal_0229	3.847e-146	481.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1WW4S@135613|Chromatiales	135613|Chromatiales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
MMD1_k127_4461532_3	1123242.JH636435_gene1247	1.907e-06	53.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2IXNK@203682|Planctomycetes	203682|Planctomycetes	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
MMD1_k127_4461532_1	1123242.JH636435_gene1731	8.382e-29	118.0	COG2094@1|root,COG2094@2|Bacteria,2J0Q4@203682|Planctomycetes	203682|Planctomycetes	L	Methylpurine-DNA glycosylase (MPG)	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
MMD1_k127_4463367_8	1444309.JAQG01000008_gene1702	5.539e-151	488.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,26QJA@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
MMD1_k127_4463367_16	1121468.AUBR01000017_gene2382	2.603e-34	144.0	COG3330@1|root,COG3330@2|Bacteria,1V2ZT@1239|Firmicutes,24H5R@186801|Clostridia,42GZA@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912
MMD1_k127_4463367_3	247490.KSU1_D0142	2.535e-246	773.0	COG1543@1|root,COG1543@2|Bacteria,2J2W9@203682|Planctomycetes	203682|Planctomycetes	G	Domain of unknown function (DUF1957)	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
MMD1_k127_4463367_6	335543.Sfum_0534	1.125e-161	522.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2MQ5I@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD linked oxidase domain protein	larD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3245	FAD-oxidase_C,FAD_binding_4
MMD1_k127_4463367_14	518766.Rmar_0611	6.658e-42	163.0	COG1376@1|root,COG1376@2|Bacteria,4P35B@976|Bacteroidetes	976|Bacteroidetes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
MMD1_k127_4463367_10	443144.GM21_3955	8.584e-102	334.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,42S5H@68525|delta/epsilon subdivisions,2WNC1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3517	Pro_CA
MMD1_k127_4463367_2	289376.THEYE_A0033	9.558e-251	789.0	COG2905@1|root,COG2905@2|Bacteria,3J0UW@40117|Nitrospirae	40117|Nitrospirae	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
MMD1_k127_4463367_15	1123376.AUIU01000013_gene1776	5.684e-38	151.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
MMD1_k127_4463367_18	1123376.AUIU01000013_gene1775	6.682e-28	116.0	COG3162@1|root,COG3162@2|Bacteria	2|Bacteria	S	Protein of unknown function, DUF485	yjcH	-	-	-	-	-	-	-	-	-	-	-	DUF485
MMD1_k127_4463367_4	289376.THEYE_A0030	2.224e-218	693.0	COG4147@1|root,COG4147@2|Bacteria	2|Bacteria	S	glycolate transport	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
MMD1_k127_4463367_1	1322246.BN4_12384	1.951e-277	868.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2M7T8@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
MMD1_k127_4463367_13	693661.Arcve_0994	2.732e-51	192.0	COG3769@1|root,arCOG01215@2157|Archaea,2XZBT@28890|Euryarchaeota	28890|Euryarchaeota	S	Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG)	mngB	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
MMD1_k127_4463367_9	580332.Slit_1785	4.579e-144	470.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria	28216|Betaproteobacteria	G	hydroxypyruvate reductase	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
MMD1_k127_4463367_5	909663.KI867151_gene3008	5.141e-164	527.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria,2MR35@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
MMD1_k127_4463367_17	909663.KI867151_gene3009	2.145e-29	126.0	COG0668@1|root,COG0668@2|Bacteria,1RK3V@1224|Proteobacteria,437YT@68525|delta/epsilon subdivisions,2X9SI@28221|Deltaproteobacteria,2MSF0@213462|Syntrophobacterales	2|Bacteria	M	transmembrane transport	ygxB	-	-	-	-	-	-	-	-	-	-	-	TM_helix
MMD1_k127_4463367_7	671143.DAMO_1541	3.558e-159	514.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
MMD1_k127_4463367_12	795359.TOPB45_1449	1.654e-75	261.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2GGUA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMD1_k127_4463367_0	1123376.AUIU01000014_gene673	0.0	1217.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,3J0UR@40117|Nitrospirae	40117|Nitrospirae	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
MMD1_k127_4463367_11	1121403.AUCV01000051_gene2125	4.761e-78	269.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NS2@68525|delta/epsilon subdivisions,2WMA0@28221|Deltaproteobacteria,2MN9Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	fdnH	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,NrfD
MMD1_k127_4463367_19	439235.Dalk_1856	4.09e-25	108.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42P2Q@68525|delta/epsilon subdivisions,2WKC2@28221|Deltaproteobacteria,2MJCP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	fdnI	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1061	NrfD
MMD1_k127_4463401_2	290397.Adeh_0109	9.64e-46	171.0	COG2864@1|root,COG3005@1|root,COG2864@2|Bacteria,COG3005@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
MMD1_k127_4463401_0	237368.SCABRO_01237	1.092e-64	230.0	2C8XG@1|root,2Z7PK@2|Bacteria,2J377@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
MMD1_k127_4463401_1	247490.KSU1_C0836	6.539e-64	224.0	COG1704@1|root,COG1704@2|Bacteria,2IZBC@203682|Planctomycetes	203682|Planctomycetes	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
MMD1_k127_4463401_3	247490.KSU1_C0835	2.381e-36	145.0	COG1512@1|root,COG1512@2|Bacteria,2J44M@203682|Planctomycetes	203682|Planctomycetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
MMD1_k127_4498173_0	330214.NIDE1304	0.0	1776.0	COG0086@1|root,COG0086@2|Bacteria,3J0BT@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
MMD1_k127_4498173_2	330214.NIDE1306	2.222e-67	230.0	COG0048@1|root,COG0048@2|Bacteria,3J0IU@40117|Nitrospirae	40117|Nitrospirae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
MMD1_k127_4498173_3	378806.STAUR_3734	2.135e-63	220.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2YUYC@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
MMD1_k127_4498173_1	243231.GSU2860	0.0	1076.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
MMD1_k127_4498173_4	754476.Q7A_2337	3.348e-17	81.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,45ZSW@72273|Thiotrichales	72273|Thiotrichales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
MMD1_k127_4498958_9	1089553.Tph_c21080	4.454e-100	342.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,42F4H@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART Elongator protein 3 MiaB NifB	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
MMD1_k127_4498958_5	760568.Desku_1329	4.507e-135	443.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,2609C@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
MMD1_k127_4498958_14	330214.NIDE2547	1.526e-70	248.0	COG1912@1|root,COG1912@2|Bacteria,3J0RG@40117|Nitrospirae	40117|Nitrospirae	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
MMD1_k127_4498958_18	765914.ThisiDRAFT_1415	1.837e-45	172.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1WWMS@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
MMD1_k127_4498958_17	330214.NIDE2558	1.615e-48	187.0	COG0558@1|root,COG0558@2|Bacteria,3J0NH@40117|Nitrospirae	40117|Nitrospirae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
MMD1_k127_4498958_15	1297742.A176_03422	7.597e-51	193.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMD1_k127_4498958_16	1232410.KI421421_gene3584	1.794e-49	181.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WP0X@28221|Deltaproteobacteria,43SHS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
MMD1_k127_4498958_6	1232410.KI421421_gene3583	1.184e-121	398.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,43S6C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SIS domain	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
MMD1_k127_4498958_7	443144.GM21_2612	4.653e-119	391.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,43TJ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM DAHP synthetase I KDSA	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
MMD1_k127_4498958_0	1121405.dsmv_1569	3.069e-251	785.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2MHTP@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
MMD1_k127_4498958_11	316067.Geob_2272	9.576e-93	313.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43T2I@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
MMD1_k127_4498958_2	269799.Gmet_1431	2.81e-158	504.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,43SIZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	uxs	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMD1_k127_4498958_1	269799.Gmet_1430	3.466e-187	594.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,43TK5@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
MMD1_k127_4498958_3	573413.Spirs_0682	6.313e-152	494.0	COG1088@1|root,COG1088@2|Bacteria,2J5ND@203691|Spirochaetes	203691|Spirochaetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
MMD1_k127_4498958_12	1158318.ATXC01000001_gene223	1.049e-89	305.0	COG1091@1|root,COG1091@2|Bacteria,2G5FQ@200783|Aquificae	200783|Aquificae	M	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	RmlD_sub_bind
MMD1_k127_4498958_13	247490.KSU1_D0777	8.41e-74	257.0	COG1898@1|root,COG1898@2|Bacteria,2IZMV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
MMD1_k127_4498958_4	247490.KSU1_D0779	1.495e-135	442.0	COG1209@1|root,COG1209@2|Bacteria,2IXSQ@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
MMD1_k127_4498958_10	330214.NIDE2553	7.533e-95	322.0	COG2870@1|root,COG2870@2|Bacteria,3J0GT@40117|Nitrospirae	40117|Nitrospirae	M	Phosphomethylpyrimidine kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
MMD1_k127_4498958_19	1499967.BAYZ01000118_gene3297	4.339e-40	159.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
MMD1_k127_4498958_8	404380.Gbem_0860	8.725e-110	364.0	COG0859@1|root,COG0859@2|Bacteria,1R5M8@1224|Proteobacteria,42N36@68525|delta/epsilon subdivisions,2WM92@28221|Deltaproteobacteria,43VZW@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
MMD1_k127_4498958_20	289376.THEYE_A0789	2.595e-21	95.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K05337,ko:K17247	-	-	-	-	ko00000	-	-	-	Fer4_13,Ferric_reduct
MMD1_k127_4498958_21	1298593.TOL_1719	2.726e-09	63.0	COG2010@1|root,COG2010@2|Bacteria,1RFJV@1224|Proteobacteria,1S4GY@1236|Gammaproteobacteria,1XPKF@135619|Oceanospirillales	135619|Oceanospirillales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
MMD1_k127_4502802_0	330214.NIDE4114	4.85e-165	530.0	COG0440@1|root,COG0460@1|root,COG0440@2|Bacteria,COG0460@2|Bacteria,3J0G1@40117|Nitrospirae	40117|Nitrospirae	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
MMD1_k127_4502802_1	8469.XP_007057779.1	0.0008077	46.0	COG0515@1|root,KOG0193@2759|Eukaryota,38F1B@33154|Opisthokonta,3BG6V@33208|Metazoa,3CWTW@33213|Bilateria,47ZID@7711|Chordata,4908J@7742|Vertebrata,4CDUY@8459|Testudines	33208|Metazoa	T	Kinase suppressor of Ras 1	KSR1	GO:0000003,GO:0000165,GO:0000578,GO:0001708,GO:0001932,GO:0001934,GO:0002009,GO:0002119,GO:0002164,GO:0002165,GO:0002252,GO:0002376,GO:0003002,GO:0003006,GO:0003674,GO:0003824,GO:0004672,GO:0005078,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005829,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006950,GO:0006952,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007264,GO:0007265,GO:0007275,GO:0007350,GO:0007351,GO:0007389,GO:0007424,GO:0007426,GO:0007444,GO:0007472,GO:0007476,GO:0007548,GO:0007552,GO:0007560,GO:0008022,GO:0008150,GO:0008152,GO:0008293,GO:0008595,GO:0009605,GO:0009607,GO:0009615,GO:0009617,GO:0009653,GO:0009790,GO:0009791,GO:0009798,GO:0009880,GO:0009886,GO:0009887,GO:0009888,GO:0009889,GO:0009893,GO:0009948,GO:0009952,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0012505,GO:0014812,GO:0016020,GO:0016301,GO:0016310,GO:0016477,GO:0016740,GO:0016772,GO:0016773,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0019933,GO:0019935,GO:0022414,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0031072,GO:0031323,GO:0031325,GO:0031326,GO:0031399,GO:0031401,GO:0031434,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032947,GO:0032991,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035282,GO:0035295,GO:0035556,GO:0035591,GO:0036211,GO:0040011,GO:0040025,GO:0040026,GO:0040028,GO:0042127,GO:0042325,GO:0042327,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043405,GO:0043408,GO:0043410,GO:0043412,GO:0043549,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045138,GO:0045165,GO:0045859,GO:0045937,GO:0046578,GO:0046579,GO:0046661,GO:0048513,GO:0048518,GO:0048522,GO:0048563,GO:0048569,GO:0048580,GO:0048582,GO:0048583,GO:0048584,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050830,GO:0050896,GO:0051056,GO:0051057,GO:0051087,GO:0051094,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051321,GO:0051338,GO:0051451,GO:0051607,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0051879,GO:0060090,GO:0060255,GO:0060429,GO:0060541,GO:0060562,GO:0061062,GO:0061063,GO:0065007,GO:0065009,GO:0071704,GO:0071889,GO:0071900,GO:0080090,GO:0090598,GO:0098542,GO:0140096,GO:1901564,GO:1902531,GO:1902533,GO:1903506,GO:2000026,GO:2000112,GO:2001141	2.7.11.1	ko:K14958,ko:K18529	ko04013,ko04014,ko05152,map04013,map04014,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	C1_1,KSR1-SAM,Pkinase_Tyr
MMD1_k127_4505898_7	378806.STAUR_7488	1.693e-68	239.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,2YUDT@29|Myxococcales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMD1_k127_4505898_13	1131269.AQVV01000046_gene2108	1.187e-11	74.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000046_gene2108|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4505898_0	1121405.dsmv_0343	7.897e-176	561.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2MI2A@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
MMD1_k127_4505898_12	269799.Gmet_3526	1.831e-31	133.0	COG4765@1|root,COG4765@2|Bacteria,1N5MU@1224|Proteobacteria,42TQ6@68525|delta/epsilon subdivisions,2WR2C@28221|Deltaproteobacteria,43VB1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2155)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2155
MMD1_k127_4505898_9	289376.THEYE_A1388	2.285e-52	191.0	COG0590@1|root,COG0590@2|Bacteria,3J0PE@40117|Nitrospirae	40117|Nitrospirae	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
MMD1_k127_4505898_16	1101189.AQUO01000002_gene728	0.0001697	46.0	COG1961@1|root,COG1961@2|Bacteria,1PFVE@1224|Proteobacteria,2V7HD@28211|Alphaproteobacteria,2PYM2@265|Paracoccus	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Zn_ribbon_recom
MMD1_k127_4505898_3	243231.GSU0094	1.197e-127	427.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
MMD1_k127_4505898_11	439235.Dalk_1999	3.434e-32	130.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria,2MK5K@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
MMD1_k127_4505898_6	428125.CLOLEP_02244	1.055e-71	249.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3WHNZ@541000|Ruminococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
MMD1_k127_4505898_5	1123376.AUIU01000014_gene654	1.728e-89	298.0	COG1014@1|root,COG1014@2|Bacteria,3J0TG@40117|Nitrospirae	40117|Nitrospirae	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
MMD1_k127_4505898_10	289376.THEYE_A0908	7.408e-41	156.0	COG1144@1|root,COG1144@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porD	-	1.2.7.1	ko:K00171,ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_21
MMD1_k127_4505898_1	289376.THEYE_A0909	3.622e-166	532.0	COG0674@1|root,COG0674@2|Bacteria,3J0HY@40117|Nitrospirae	40117|Nitrospirae	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
MMD1_k127_4505898_2	903818.KI912268_gene798	7.88e-137	441.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0018	TPP_enzyme_C
MMD1_k127_4505898_8	404380.Gbem_3963	1.778e-62	219.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
MMD1_k127_4505898_4	290397.Adeh_3633	4.551e-108	352.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
MMD1_k127_4505898_14	443144.GM21_0018	6.634e-09	59.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42VGM@68525|delta/epsilon subdivisions,2WSQ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Excinuclease ABC, C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
MMD1_k127_4506692_1	443143.GM18_2447	6.848e-136	453.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
MMD1_k127_4506692_7	1173027.Mic7113_3304	4.451e-50	180.0	COG0662@1|root,COG0662@2|Bacteria,1G6DB@1117|Cyanobacteria,1HBDP@1150|Oscillatoriales	1117|Cyanobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD1_k127_4506692_6	909663.KI867150_gene2903	2.377e-75	256.0	COG1853@1|root,COG1853@2|Bacteria,1PD49@1224|Proteobacteria,42VJC@68525|delta/epsilon subdivisions,2WRZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
MMD1_k127_4506692_8	443143.GM18_0939	1.368e-19	98.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
MMD1_k127_4506692_3	338963.Pcar_2558	1.302e-118	411.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg
MMD1_k127_4506692_4	716928.AJQT01000047_gene2152	2.124e-108	357.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria,4B7QA@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter (Permease	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
MMD1_k127_4506692_5	716928.AJQT01000047_gene2151	9.095e-97	325.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TUAN@28211|Alphaproteobacteria,4B76N@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter permease	MA20_03545	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
MMD1_k127_4506692_2	1038859.AXAU01000018_gene6727	1.551e-120	395.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,3JQYC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
MMD1_k127_4506692_0	716928.AJQT01000047_gene2149	3.781e-180	578.0	COG1653@1|root,COG1653@2|Bacteria,1MU64@1224|Proteobacteria,2VFE8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
MMD1_k127_4535839_1	1123368.AUIS01000006_gene666	1.262e-181	583.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,2NCKR@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Proton-conducting membrane transporter	nuoM	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iSDY_1059.SDY_2473	Proton_antipo_M
MMD1_k127_4535839_0	1123368.AUIS01000006_gene665	9.157e-231	732.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,2NCNU@225057|Acidithiobacillales	225057|Acidithiobacillales	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
MMD1_k127_4535839_2	706587.Desti_4753	2.594e-32	126.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK-2	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMD1_k127_4538947_13	479434.Sthe_1223	1.257e-07	63.0	COG0823@1|root,COG0823@2|Bacteria,2G8Z9@200795|Chloroflexi,27XTF@189775|Thermomicrobia	189775|Thermomicrobia	U	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
MMD1_k127_4538947_0	292459.STH1455	2.892e-183	617.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
MMD1_k127_4538947_5	439235.Dalk_2888	6.554e-123	414.0	28M0D@1|root,2ZAFE@2|Bacteria,1R6YH@1224|Proteobacteria,42NPF@68525|delta/epsilon subdivisions,2WM7K@28221|Deltaproteobacteria,2MIG7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
MMD1_k127_4538947_14	59196.RICGR_0190	1.353e-07	59.0	2BYFY@1|root,33EM6@2|Bacteria,1NIAK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4538947_7	1499967.BAYZ01000152_gene1432	1.136e-91	314.0	COG1131@1|root,COG1131@2|Bacteria,2NPDQ@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	natA2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_4538947_10	96561.Dole_0148	4.345e-65	241.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
MMD1_k127_4538947_16	460265.Mnod_7207	0.0002072	55.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,2U1FH@28211|Alphaproteobacteria,1JRUY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
MMD1_k127_4538947_1	443144.GM21_0944	4.567e-170	554.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD1_k127_4538947_9	316067.Geob_0431	5.101e-68	252.0	COG0500@1|root,COG2226@2|Bacteria,1RFBE@1224|Proteobacteria,42VEH@68525|delta/epsilon subdivisions,2WVST@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
MMD1_k127_4538947_2	404380.Gbem_3307	1.187e-154	497.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
MMD1_k127_4538947_8	316067.Geob_0429	6.101e-73	260.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,43AJA@68525|delta/epsilon subdivisions,2X5ZM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
MMD1_k127_4538947_3	316067.Geob_0428	1.922e-152	496.0	2CCXX@1|root,2Z8MY@2|Bacteria,1RE6D@1224|Proteobacteria,42YFY@68525|delta/epsilon subdivisions,2WUKJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NDP-hexose 23-dehydratase	-	-	4.2.1.159	ko:K16435	ko00523,ko01055,ko01130,map00523,map01055,map01130	M00798,M00799,M00800,M00801,M00802,M00803	R05518,R06428	RC00782,RC01448	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexose_dehydrat
MMD1_k127_4538947_6	316067.Geob_0427	2.404e-114	379.0	COG0463@1|root,COG0463@2|Bacteria,1RCVF@1224|Proteobacteria,43CNQ@68525|delta/epsilon subdivisions,2WUDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
MMD1_k127_4538947_11	84531.JMTZ01000036_gene460	1.35e-14	79.0	2EUIT@1|root,33N0U@2|Bacteria,1NMNE@1224|Proteobacteria,1SHKN@1236|Gammaproteobacteria,1X7S4@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
MMD1_k127_4538947_4	378806.STAUR_1844	3.532e-140	467.0	COG2374@1|root,COG5492@1|root,COG2374@2|Bacteria,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,42UE8@68525|delta/epsilon subdivisions,2WVIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
MMD1_k127_4538947_12	404589.Anae109_0557	3.851e-11	73.0	2BZY2@1|root,2ZMII@2|Bacteria,1P6VB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4558532_3	243231.GSU2038	8.542e-70	245.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WKJV@28221|Deltaproteobacteria,43T8W@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_5,Neisseria_PilC
MMD1_k127_4558532_10	1158338.JNLJ01000001_gene688	1.137e-11	71.0	COG4967@1|root,COG4967@2|Bacteria,2G4DN@200783|Aquificae	200783|Aquificae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
MMD1_k127_4558532_4	909663.KI867149_gene3438	8.041e-66	238.0	COG4968@1|root,COG4968@2|Bacteria,1REDT@1224|Proteobacteria,42RY5@68525|delta/epsilon subdivisions,2WNPG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	pilW-2	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
MMD1_k127_4558532_11	338966.Ppro_0991	2.361e-10	70.0	2E6Z6@1|root,331IC@2|Bacteria,1NY0D@1224|Proteobacteria,430VK@68525|delta/epsilon subdivisions,2WVKD@28221|Deltaproteobacteria,43VJN@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	pilX-2	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4558532_7	1232410.KI421416_gene2603	6.548e-27	122.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,Laminin_G_3,RHS_repeat,SprB
MMD1_k127_4558532_6	330214.NIDE4090	1.647e-31	137.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,Laminin_G_3,RHS_repeat,SprB
MMD1_k127_4558532_5	555079.Toce_0738	5.538e-55	198.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,42GIM@68295|Thermoanaerobacterales	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
MMD1_k127_4558532_9	401053.AciPR4_0836	6.905e-17	89.0	COG2197@1|root,COG2197@2|Bacteria,3Y2WY@57723|Acidobacteria,2JIR0@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
MMD1_k127_4558532_2	243231.GSU1819	3.629e-98	332.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,43TES@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	integrase domain protein SAM domain protein	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
MMD1_k127_4558532_0	243231.GSU1581	2.207e-263	837.0	COG0617@1|root,COG0618@1|root,COG3620@1|root,COG0617@2|Bacteria,COG0618@2|Bacteria,COG3620@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,43U0J@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	CBS domain containing protein	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
MMD1_k127_4558532_1	767817.Desgi_2133	9.057e-103	349.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,26105@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM Na Pi-cotransporter II-related protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
MMD1_k127_4588698_0	289376.THEYE_A0629	0.0	1030.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,3J0TJ@40117|Nitrospirae	40117|Nitrospirae	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
MMD1_k127_4588698_18	1162668.LFE_2384	1.179e-26	115.0	COG1664@1|root,COG1664@2|Bacteria,3J1F5@40117|Nitrospirae	40117|Nitrospirae	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
MMD1_k127_4588698_11	289376.THEYE_A1991	1.931e-73	256.0	COG1475@1|root,COG1475@2|Bacteria,3J0K9@40117|Nitrospirae	40117|Nitrospirae	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
MMD1_k127_4588698_8	1089550.ATTH01000001_gene2122	3.389e-98	327.0	COG1192@1|root,COG1192@2|Bacteria,4NFEX@976|Bacteroidetes,1FJ0J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Cellulose biosynthesis protein BcsQ	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
MMD1_k127_4588698_14	247490.KSU1_C0698	9.714e-42	168.0	COG1341@1|root,COG1341@2|Bacteria	2|Bacteria	S	polynucleotide 5'-hydroxyl-kinase activity	-	-	-	ko:K06947	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CLP1_P
MMD1_k127_4588698_16	203119.Cthe_2363	4.461e-33	138.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3WIRQ@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
MMD1_k127_4588698_2	243231.GSU3464	2.779e-249	784.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,43TF6@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
MMD1_k127_4588698_6	1121468.AUBR01000004_gene114	2.794e-133	438.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,42FFQ@68295|Thermoanaerobacterales	186801|Clostridia	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
MMD1_k127_4588698_3	316067.Geob_1498	1.306e-206	660.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
MMD1_k127_4588698_9	1131269.AQVV01000024_gene2355	5.249e-96	327.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
MMD1_k127_4588698_19	1235835.C814_02817	1.614e-20	93.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3WKVK@541000|Ruminococcaceae	186801|Clostridia	L	GIY-YIG catalytic domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
MMD1_k127_4588698_17	1443122.Z958_01730	6.634e-29	124.0	COG1051@1|root,COG1051@2|Bacteria,1V5NQ@1239|Firmicutes,24PPQ@186801|Clostridia,36K3B@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
MMD1_k127_4588698_12	552811.Dehly_0288	3.044e-45	173.0	COG0563@1|root,COG0563@2|Bacteria	2|Bacteria	F	adenylate kinase activity	adk	-	2.7.4.3,6.3.4.4	ko:K00939,ko:K01939	ko00230,ko00250,ko00730,ko01100,ko01110,ko01130,map00230,map00250,map00730,map01100,map01110,map01130	M00049	R00127,R01135,R01547,R11319	RC00002,RC00458,RC00459	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMD1_k127_4588698_10	1232410.KI421424_gene1844	3.723e-82	276.0	COG1896@1|root,COG1896@2|Bacteria,1R71H@1224|Proteobacteria,42NGN@68525|delta/epsilon subdivisions,2WKMF@28221|Deltaproteobacteria,43S2K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
MMD1_k127_4588698_20	1123507.ATVQ01000003_gene617	1.77e-07	58.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K06039,ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
MMD1_k127_4588698_15	215803.DB30_8168	1.009e-41	157.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WQWW@28221|Deltaproteobacteria,2YW79@29|Myxococcales	28221|Deltaproteobacteria	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
MMD1_k127_4588698_13	1121324.CLIT_11c01360	8.459e-42	160.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,25TNE@186804|Peptostreptococcaceae	186801|Clostridia	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
MMD1_k127_4588698_5	330214.NIDE0001	3.677e-135	443.0	COG0593@1|root,COG0593@2|Bacteria,3J0FQ@40117|Nitrospirae	40117|Nitrospirae	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
MMD1_k127_4588698_7	330214.NIDE0002	3.97e-120	396.0	COG0592@1|root,COG0592@2|Bacteria,3J0RU@40117|Nitrospirae	40117|Nitrospirae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
MMD1_k127_4588698_1	1232410.KI421422_gene2032	3.281e-296	932.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43SYW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
MMD1_k127_4588698_4	118005.AWNK01000016_gene987	9.639e-198	626.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
MMD1_k127_4604523_12	883.DvMF_1984	1.846e-25	112.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,42MRE@68525|delta/epsilon subdivisions,2WIP0@28221|Deltaproteobacteria,2M81I@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_4604523_8	289376.THEYE_A0727	1.004e-33	139.0	COG2188@1|root,COG2188@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
MMD1_k127_4604523_1	1123376.AUIU01000011_gene982	1.884e-145	474.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02584,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat
MMD1_k127_4604523_5	713586.KB900536_gene2038	4.091e-56	208.0	COG0589@1|root,COG0589@2|Bacteria,1NBKV@1224|Proteobacteria,1SHMY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Universal stress protein family	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE,Usp
MMD1_k127_4604523_11	909663.KI867150_gene187	1.738e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2MS84@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	SMART Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
MMD1_k127_4604523_14	338963.Pcar_2255	5.384e-10	63.0	COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,42XSC@68525|delta/epsilon subdivisions,2WT18@28221|Deltaproteobacteria,43SSB@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein S21	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
MMD1_k127_4604523_10	1265502.KB905947_gene1071	5.107e-28	116.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,4AE4Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
MMD1_k127_4604523_13	56780.SYN_03122	1.769e-12	74.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4604523_3	335543.Sfum_1996	5.542e-100	342.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
MMD1_k127_4604523_2	1408473.JHXO01000005_gene1751	3.6e-119	391.0	COG1180@1|root,COG1180@2|Bacteria,4NJ18@976|Bacteroidetes,2FQZB@200643|Bacteroidia	976|Bacteroidetes	O	radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
MMD1_k127_4604523_7	1131462.DCF50_p2376	4.968e-40	164.0	COG0348@1|root,COG4659@1|root,COG0348@2|Bacteria,COG4659@2|Bacteria,1UYBF@1239|Firmicutes,24A2I@186801|Clostridia,2617U@186807|Peptococcaceae	186801|Clostridia	C	PFAM FMN-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
MMD1_k127_4604523_4	1499967.BAYZ01000096_gene4315	1.56e-71	268.0	COG0421@1|root,COG0421@2|Bacteria,2NNTV@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
MMD1_k127_4604523_15	1121918.ARWE01000001_gene368	4.945e-05	55.0	COG0457@1|root,COG0666@1|root,COG0457@2|Bacteria,COG0666@2|Bacteria,1PGQM@1224|Proteobacteria,433NE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4604523_0	768670.Calni_0484	7.637e-246	772.0	COG3303@1|root,COG3303@2|Bacteria,2GGAT@200930|Deferribacteres	200930|Deferribacteres	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552
MMD1_k127_4604523_6	443144.GM21_2036	5.771e-47	177.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
MMD1_k127_4604523_9	1167006.UWK_00092	1.143e-29	120.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,42MXX@68525|delta/epsilon subdivisions,2WKJM@28221|Deltaproteobacteria,2MHQS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMD1_k127_4642543_8	316067.Geob_2912	2.235e-48	180.0	COG3005@1|root,COG3005@2|Bacteria,1RHMA@1224|Proteobacteria,42Z4M@68525|delta/epsilon subdivisions,2WU8J@28221|Deltaproteobacteria,43U75@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	cytochrome C	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_4642543_3	243231.GSU2737	8.457e-71	269.0	COG3005@1|root,COG3005@2|Bacteria,1QXPB@1224|Proteobacteria,43C54@68525|delta/epsilon subdivisions,2X7FH@28221|Deltaproteobacteria,43V7W@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	anaerobic electron transport chain	-	GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4642543_10	309807.SRU_2606	1.868e-26	117.0	COG0835@1|root,COG0835@2|Bacteria,4NTK7@976|Bacteroidetes,1FK3X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	NT	Two component signalling adaptor domain	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
MMD1_k127_4642543_2	404380.Gbem_0741	4.19e-82	282.0	COG3267@1|root,COG3267@2|Bacteria,1REY9@1224|Proteobacteria,42RJB@68525|delta/epsilon subdivisions,2WN99@28221|Deltaproteobacteria,43TEB@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
MMD1_k127_4642543_1	290397.Adeh_2736	1.379e-163	538.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2YU8D@29|Myxococcales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric domain	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
MMD1_k127_4642543_9	1144275.COCOR_02637	1.801e-38	147.0	COG0745@1|root,COG0745@2|Bacteria,1N1TA@1224|Proteobacteria,42V03@68525|delta/epsilon subdivisions,2WPZR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	cheY40H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
MMD1_k127_4642543_5	269799.Gmet_2313	4.971e-66	241.0	COG0745@1|root,COG0745@2|Bacteria,1N9YT@1224|Proteobacteria,42W15@68525|delta/epsilon subdivisions,2WS2V@28221|Deltaproteobacteria,43T56@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	regulator, PATAN and FRGAF domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
MMD1_k127_4642543_4	717605.Theco_2030	8.048e-67	231.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,4HHVD@91061|Bacilli,26WQF@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0234 family	yitK	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
MMD1_k127_4642543_11	228410.NE1052	1.548e-12	77.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,37343@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
MMD1_k127_4642543_0	56780.SYN_01274	2.063e-186	606.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2MQB8@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
MMD1_k127_4642543_6	767817.Desgi_1872	1e-65	233.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,260XY@186807|Peptococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
MMD1_k127_4642543_12	1278309.KB907102_gene181	3.194e-12	73.0	2AH4X@1|root,317EK@2|Bacteria,1RHUE@1224|Proteobacteria,1SDQZ@1236|Gammaproteobacteria,1XPPM@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4642543_7	1042163.BRLA_c003440	2.419e-65	231.0	COG2258@1|root,COG2258@2|Bacteria,1UB2C@1239|Firmicutes,4HB26@91061|Bacilli,26T6I@186822|Paenibacillaceae	91061|Bacilli	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
MMD1_k127_4664715_0	1499967.BAYZ01000186_gene3978	1.201e-145	493.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NRA2@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Bac_surface_Ag,PD40
MMD1_k127_468858_2	289376.THEYE_A1784	2.622e-42	155.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	MGDG_synth,PHP
MMD1_k127_468858_3	1232410.KI421421_gene3411	1.59e-26	115.0	COG0745@1|root,COG0745@2|Bacteria,1P0HX@1224|Proteobacteria,431WT@68525|delta/epsilon subdivisions,2WWE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_468858_0	289376.THEYE_A1778	3.916e-142	458.0	COG0226@1|root,COG0226@2|Bacteria,3J143@40117|Nitrospirae	40117|Nitrospirae	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
MMD1_k127_468858_1	123214.PERMA_1573	2.34e-124	408.0	COG0573@1|root,COG0573@2|Bacteria,2G3QM@200783|Aquificae	200783|Aquificae	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMD1_k127_4693545_3	289376.THEYE_A1325	8.589e-61	224.0	COG1686@1|root,COG1686@2|Bacteria,3J179@40117|Nitrospirae	40117|Nitrospirae	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
MMD1_k127_4693545_2	335543.Sfum_3054	2.99e-66	233.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,42RSE@68525|delta/epsilon subdivisions,2WP0K@28221|Deltaproteobacteria,2MRU0@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
MMD1_k127_4693545_1	439235.Dalk_1595	3.437e-95	326.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,42P7C@68525|delta/epsilon subdivisions,2WKKF@28221|Deltaproteobacteria,2MIJE@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM MltA	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
MMD1_k127_4693545_0	706587.Desti_0167	1.757e-301	932.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42MZJ@68525|delta/epsilon subdivisions,2WJK1@28221|Deltaproteobacteria,2MQ7S@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
MMD1_k127_4694685_0	323261.Noc_1125	7.003e-170	539.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoCD	-	1.6.5.3	ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
MMD1_k127_4694685_2	323261.Noc_1126	5.969e-99	327.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
MMD1_k127_4694685_5	706587.Desti_4762	6.078e-45	169.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42U92@68525|delta/epsilon subdivisions,2WQCK@28221|Deltaproteobacteria,2MS5J@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
MMD1_k127_4694685_4	909663.KI867150_gene711	5.822e-73	255.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,43A29@68525|delta/epsilon subdivisions,2X21K@28221|Deltaproteobacteria,2MS4J@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
MMD1_k127_4694685_3	589865.DaAHT2_1314	2.046e-87	292.0	COG0655@1|root,COG0655@2|Bacteria,1RAK6@1224|Proteobacteria,42QS5@68525|delta/epsilon subdivisions,2WN2M@28221|Deltaproteobacteria,2MJW8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
MMD1_k127_4694685_1	1485544.JQKP01000003_gene201	1.817e-115	376.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,2VJB9@28216|Betaproteobacteria	28216|Betaproteobacteria	P	membrane protein, terc	alx	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
MMD1_k127_4702978_0	123214.PERMA_1574	7.781e-123	399.0	COG0581@1|root,COG0581@2|Bacteria,2G3SA@200783|Aquificae	200783|Aquificae	P	PFAM binding-protein-dependent transport systems inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
MMD1_k127_4702978_1	289376.THEYE_A1792	9.069e-120	390.0	COG1117@1|root,COG1117@2|Bacteria,3J0EU@40117|Nitrospirae	40117|Nitrospirae	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
MMD1_k127_4702978_2	330214.NIDE2416	3.772e-76	261.0	COG0704@1|root,COG0704@2|Bacteria,3J0M6@40117|Nitrospirae	40117|Nitrospirae	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
MMD1_k127_4702978_3	1396141.BATP01000034_gene4190	7.041e-57	204.0	COG1807@1|root,COG1807@2|Bacteria,46SXK@74201|Verrucomicrobia,2IVX4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
MMD1_k127_4710993_2	316274.Haur_1657	1.541e-80	277.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,Ser_hydrolase
MMD1_k127_4710993_0	909663.KI867150_gene72	3.411e-190	608.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2MRD6@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
MMD1_k127_4710993_3	1250232.JQNJ01000001_gene1941	2.137e-05	56.0	2A7J6@1|root,30WGZ@2|Bacteria,4NNP5@976|Bacteroidetes,1I2HA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4710993_1	909663.KI867149_gene3402	2.829e-81	277.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2MQFC@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
MMD1_k127_4724277_0	368407.Memar_1498	3.437e-83	308.0	COG0210@1|root,arCOG00802@2157|Archaea	2157|Archaea	L	UvrD REP helicase	-	-	3.6.4.12	ko:K03657,ko:K16898	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
MMD1_k127_4769908_6	247490.KSU1_D0106	1.786e-42	160.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMD1_k127_4769908_3	398767.Glov_1270	1.941e-55	206.0	2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,4330X@68525|delta/epsilon subdivisions,2WXN7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4769908_0	1131462.DCF50_p1172	5.139e-211	667.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,2612Q@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
MMD1_k127_4769908_5	1469607.KK073768_gene1099	1.266e-50	195.0	COG2199@1|root,COG3706@2|Bacteria,1G3NI@1117|Cyanobacteria,1HMYF@1161|Nostocales	1117|Cyanobacteria	T	COGs COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
MMD1_k127_4769908_10	246969.TAM4_913	1.932e-05	58.0	COG4945@1|root,arCOG02559@1|root,arCOG03264@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG03771@2157|Archaea,2XSTV@28890|Euryarchaeota,243KF@183968|Thermococci	183968|Thermococci	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C,PEGA
MMD1_k127_4769908_7	1125863.JAFN01000001_gene2816	7.287e-27	124.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
MMD1_k127_4769908_12	1284775.HMPREF1640_00890	0.0002636	53.0	COG0457@1|root,COG0457@2|Bacteria,4NDV9@976|Bacteroidetes,2FNGB@200643|Bacteroidia	976|Bacteroidetes	D	Tetratricopeptide repeat protein	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
MMD1_k127_4769908_2	1125863.JAFN01000001_gene2822	1.206e-120	407.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
MMD1_k127_4769908_4	1178540.BA70_05190	1.179e-53	202.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,1ZCAV@1386|Bacillus	91061|Bacilli	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	appB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
MMD1_k127_4769908_1	177439.DP2415	3.795e-155	501.0	COG0006@1|root,COG0006@2|Bacteria,1N763@1224|Proteobacteria,42PVQ@68525|delta/epsilon subdivisions,2WK4N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM peptidase M24	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
MMD1_k127_4769908_9	694429.Pyrfu_0334	5.797e-14	78.0	arCOG06398@1|root,arCOG06398@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4769908_11	388467.A19Y_1683	2.064e-05	51.0	2EFKE@1|root,339CQ@2|Bacteria,1G9TA@1117|Cyanobacteria,1HGHK@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4769908_8	1485545.JQLW01000009_gene146	7.676e-23	104.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria	1224|Proteobacteria	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
MMD1_k127_4770697_0	536227.CcarbDRAFT_5039	6.849e-76	262.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,36DPP@31979|Clostridiaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
MMD1_k127_4770697_1	667014.Thein_1492	1.942e-31	136.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos,PQQ_2,PQQ_3
MMD1_k127_4770697_4	243231.GSU0564	0.0001479	46.0	COG2888@1|root,COG2888@2|Bacteria,1MZH3@1224|Proteobacteria,42VBG@68525|delta/epsilon subdivisions,2WTZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4770697_3	247490.KSU1_D0176	5.611e-11	63.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
MMD1_k127_4770697_2	373903.Hore_15730	6.48e-16	78.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WAD7@53433|Halanaerobiales	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
MMD1_k127_4791330_2	1123376.AUIU01000011_gene814	1.544e-28	115.0	COG0070@1|root,COG0493@1|root,COG1143@1|root,COG0070@2|Bacteria,COG0493@2|Bacteria,COG1143@2|Bacteria,3J152@40117|Nitrospirae	40117|Nitrospirae	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_20,GXGXG,Pyr_redox_2,Pyr_redox_3
MMD1_k127_4791330_4	1282362.AEAC466_08760	2.134e-06	56.0	2EREC@1|root,33IZX@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1523
MMD1_k127_4791330_0	96561.Dole_3193	1.982e-89	311.0	COG2199@1|root,COG3850@1|root,COG2199@2|Bacteria,COG3850@2|Bacteria,1NT1K@1224|Proteobacteria,42R1P@68525|delta/epsilon subdivisions,2WN0S@28221|Deltaproteobacteria,2MMVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
MMD1_k127_4791330_1	443144.GM21_0034	8.548e-49	185.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,43TPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
MMD1_k127_4813115_1	177437.HRM2_11540	5.331e-84	284.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,42PC9@68525|delta/epsilon subdivisions,2WKA4@28221|Deltaproteobacteria,2MJ22@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
MMD1_k127_4813115_3	1042375.AFPL01000004_gene605	7.16e-50	183.0	29FS0@1|root,302PP@2|Bacteria,1RE1Q@1224|Proteobacteria,1S4I9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4813115_0	247490.KSU1_D0148	1.112e-94	326.0	COG1723@1|root,COG1723@2|Bacteria,2J0AJ@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4813115_4	1122221.JHVI01000017_gene2093	5.152e-44	167.0	COG2905@1|root,COG2905@2|Bacteria,1WJV4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
MMD1_k127_4813115_2	56780.SYN_00196	3.133e-56	203.0	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,42XQK@68525|delta/epsilon subdivisions,2WSNS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
MMD1_k127_4844873_0	690850.Desaf_1218	0.0	1028.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2M8T9@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	ATPase BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
MMD1_k127_4844873_4	448385.sce5467	4.025e-47	188.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42MCH@68525|delta/epsilon subdivisions,2WJPZ@28221|Deltaproteobacteria,2Z39Q@29|Myxococcales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
MMD1_k127_4844873_6	1232410.KI421415_gene3020	1.132e-05	51.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,42NJD@68525|delta/epsilon subdivisions,2WJFK@28221|Deltaproteobacteria,43THJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the peptidase S16 family	-	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C,Mg_chelatase
MMD1_k127_4844873_5	1121935.AQXX01000042_gene4588	1.371e-30	134.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1S5X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4844873_2	1499967.BAYZ01000181_gene4506	4.437e-68	239.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
MMD1_k127_4844873_3	1499967.BAYZ01000181_gene4505	2.932e-56	213.0	COG4585@1|root,COG5002@1|root,COG4585@2|Bacteria,COG5002@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HAMP,HATPase_c,HisKA_3,PAS,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
MMD1_k127_4844873_1	429009.Adeg_0177	2.1e-230	744.0	COG1067@1|root,COG1674@1|root,COG1067@2|Bacteria,COG1674@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,42FSR@68295|Thermoanaerobacterales	186801|Clostridia	O	Endopeptidase La	-	-	3.4.21.53	ko:K04076	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AAA_32,Lon_C
MMD1_k127_4859315_1	96561.Dole_0045	1.833e-14	75.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,2MKX6@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
MMD1_k127_4859315_0	1157490.EL26_16435	1.708e-133	446.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,277ZT@186823|Alicyclobacillaceae	91061|Bacilli	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
MMD1_k127_4860961_0	243231.GSU0281	2.312e-79	278.0	COG3920@1|root,COG4191@1|root,COG3920@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,HisKA_3,HisKA_7TM,PAS_8
MMD1_k127_4860961_3	1380394.JADL01000003_gene4748	4.64e-54	194.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,2JSN1@204441|Rhodospirillales	204441|Rhodospirillales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
MMD1_k127_4860961_2	909663.KI867150_gene448	4.405e-63	220.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria,2MQI0@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
MMD1_k127_4860961_1	1123393.KB891317_gene2209	5.182e-68	231.0	COG0662@1|root,COG0662@2|Bacteria,1QW6S@1224|Proteobacteria	1224|Proteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
MMD1_k127_4860961_4	1232683.ADIMK_0861	1.786e-46	172.0	COG0563@1|root,COG0563@2|Bacteria,1RCIS@1224|Proteobacteria,1S692@1236|Gammaproteobacteria,467RY@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	COG0563 Adenylate kinase and related kinases	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4896176_6	697282.Mettu_3958	1.992e-49	178.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,1S6K5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
MMD1_k127_4896176_0	696281.Desru_0554	2.296e-130	431.0	COG2221@1|root,COG2221@2|Bacteria,1UMIE@1239|Firmicutes,25GJC@186801|Clostridia,267FE@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
MMD1_k127_4896176_5	1283283.ATXA01000010_gene4498	1.286e-53	195.0	COG3832@1|root,COG3832@2|Bacteria,2IRUM@201174|Actinobacteria,4EVXE@85013|Frankiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
MMD1_k127_4896176_7	290318.Cvib_0036	2.368e-22	98.0	COG0425@1|root,COG0425@2|Bacteria,1FE4M@1090|Chlorobi	1090|Chlorobi	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
MMD1_k127_4896176_4	156889.Mmc1_3745	2.239e-55	198.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2U6FZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
MMD1_k127_4896176_2	243231.GSU2530	5.375e-98	332.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42MQV@68525|delta/epsilon subdivisions,2WIZC@28221|Deltaproteobacteria,43S0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
MMD1_k127_4896176_3	398527.Bphyt_2248	6.313e-83	287.0	COG1028@1|root,COG1028@2|Bacteria,1PVWT@1224|Proteobacteria,2W0R4@28216|Betaproteobacteria,1K64Y@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
MMD1_k127_4896176_1	391625.PPSIR1_00300	1.145e-101	341.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42P72@68525|delta/epsilon subdivisions,2WKRS@28221|Deltaproteobacteria,2YXDE@29|Myxococcales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	gyaR	-	1.1.1.26	ko:K00015,ko:K15893	ko00260,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map01100,map01110,map01120,map01130,map01200	M00532	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
MMD1_k127_4950235_2	243233.MCA1142	1.14e-36	145.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,1RM9Q@1236|Gammaproteobacteria,1XDSI@135618|Methylococcales	135618|Methylococcales	C	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
MMD1_k127_4950235_0	1116472.MGMO_167c00190	1.808e-99	333.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,1RPCY@1236|Gammaproteobacteria,1XE7T@135618|Methylococcales	135618|Methylococcales	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
MMD1_k127_4950235_1	1122604.JONR01000030_gene1325	2.798e-68	239.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,1RRYF@1236|Gammaproteobacteria,1X9HR@135614|Xanthomonadales	135614|Xanthomonadales	C	hydrogenase 4 membrane	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
MMD1_k127_4950235_3	1123393.KB891316_gene1982	1.633e-12	70.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria,1KSWH@119069|Hydrogenophilales	119069|Hydrogenophilales	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
MMD1_k127_4956785_4	525904.Tter_0610	7.858e-52	195.0	COG3301@1|root,COG3301@2|Bacteria,2NQZC@2323|unclassified Bacteria	2|Bacteria	P	Polysulfide reductase	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
MMD1_k127_4956785_7	309801.trd_A0061	1.782e-26	121.0	COG3058@1|root,COG3058@2|Bacteria,2G9S5@200795|Chloroflexi,27YFM@189775|Thermomicrobia	189775|Thermomicrobia	O	Protein involved in formate dehydrogenase formation	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
MMD1_k127_4956785_6	706587.Desti_1110	5.562e-47	176.0	COG2227@1|root,COG2227@2|Bacteria,1RIMR@1224|Proteobacteria,43CQM@68525|delta/epsilon subdivisions,2X7Y3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4956785_0	338966.Ppro_1454	2.361e-113	381.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2WJ06@28221|Deltaproteobacteria,43W0W@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
MMD1_k127_4956785_3	935948.KE386494_gene710	3.743e-59	217.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,42EKM@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
MMD1_k127_4956785_2	247490.KSU1_C0374	2.151e-67	238.0	28PU4@1|root,2ZCF6@2|Bacteria,2J30W@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_4956785_1	243231.GSU1185	3.623e-78	264.0	COG1839@1|root,COG1839@2|Bacteria,1RBCB@1224|Proteobacteria,42S44@68525|delta/epsilon subdivisions,2WMAS@28221|Deltaproteobacteria,43UGI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
MMD1_k127_4956785_5	289376.THEYE_A1452	4.484e-51	191.0	28Q1P@1|root,2ZCJY@2|Bacteria	2|Bacteria	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
MMD1_k127_4956785_8	269799.Gmet_0858	2.258e-22	96.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WPDW@28221|Deltaproteobacteria,43U17@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
MMD1_k127_5060592_3	557599.MKAN_28795	4.529e-48	181.0	28MQW@1|root,32WFA@2|Bacteria,2I50D@201174|Actinobacteria,23F8X@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5060592_2	1232410.KI421418_gene2358	7.236e-56	200.0	COG2303@1|root,COG2365@1|root,COG2303@2|Bacteria,COG2365@2|Bacteria,1RGE7@1224|Proteobacteria,42U1M@68525|delta/epsilon subdivisions,2WQE0@28221|Deltaproteobacteria,43W3C@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
MMD1_k127_5060592_0	316067.Geob_3539	1.55e-151	488.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria,43TNQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
MMD1_k127_5060592_1	635013.TherJR_1433	1.652e-138	453.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,26141@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
MMD1_k127_50761_1	589924.Ferp_1758	1.387e-63	228.0	COG0407@1|root,arCOG03323@2157|Archaea,2XV21@28890|Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
MMD1_k127_50761_3	1379270.AUXF01000002_gene1178	2.93e-06	53.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
MMD1_k127_50761_0	1123325.JHUV01000008_gene607	5.358e-83	286.0	COG0685@1|root,COG0685@2|Bacteria,2G4CV@200783|Aquificae	200783|Aquificae	E	Methylenetetrahydrofolate reductase	metF	GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
MMD1_k127_50761_2	635013.TherJR_0989	1.5e-21	98.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,2605Z@186807|Peptococcaceae	186801|Clostridia	S	Cobalamin synthesis protein cobW C-terminal domain	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
MMD1_k127_5106464_4	1232410.KI421425_gene1548	5.988e-13	76.0	COG0457@1|root,COG0457@2|Bacteria,1N1J2@1224|Proteobacteria,42ZHG@68525|delta/epsilon subdivisions,2WV2W@28221|Deltaproteobacteria,43UR6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5106464_0	1232410.KI421425_gene1549	0.0	1336.0	COG4105@1|root,COG4105@2|Bacteria,1QVQ9@1224|Proteobacteria,43CT2@68525|delta/epsilon subdivisions,2X80K@28221|Deltaproteobacteria,43TUA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
MMD1_k127_5106464_2	1232410.KI421425_gene1550	1.978e-281	876.0	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,42Z0Q@68525|delta/epsilon subdivisions,2WU0G@28221|Deltaproteobacteria,43T6R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5106464_3	1232410.KI421425_gene1551	4.215e-65	229.0	2B4XH@1|root,32REP@2|Bacteria,1PXEZ@1224|Proteobacteria,4305C@68525|delta/epsilon subdivisions,2WVH5@28221|Deltaproteobacteria,43UUP@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5106464_1	1232410.KI421425_gene1552	0.0	1191.0	COG2885@1|root,COG2885@2|Bacteria,1QW22@1224|Proteobacteria,42TDV@68525|delta/epsilon subdivisions,2WP7K@28221|Deltaproteobacteria,43UHJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
MMD1_k127_5126372_0	1232410.KI421425_gene1554	0.0	1318.0	COG1361@1|root,COG1361@2|Bacteria,1R5G4@1224|Proteobacteria,42T0V@68525|delta/epsilon subdivisions,2WPRT@28221|Deltaproteobacteria,43TPS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
MMD1_k127_5126372_16	269799.Gmet_2157	1.81e-19	98.0	COG2204@1|root,COG2207@1|root,COG2204@2|Bacteria,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,42XG8@68525|delta/epsilon subdivisions,2WT82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
MMD1_k127_5126372_13	575593.HMPREF0491_01109	2.505e-27	122.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,25BFB@186801|Clostridia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AraC,Response_reg
MMD1_k127_5126372_6	1121405.dsmv_1539	8.28e-64	226.0	28PW7@1|root,32EDN@2|Bacteria,1N0AP@1224|Proteobacteria,42UF5@68525|delta/epsilon subdivisions,2WQ2P@28221|Deltaproteobacteria,2MKES@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
MMD1_k127_5126372_15	868595.Desca_2288	7.041e-24	104.0	COG1872@1|root,COG1872@2|Bacteria,1VFSH@1239|Firmicutes,24T87@186801|Clostridia,262RJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
MMD1_k127_5126372_14	289376.THEYE_A1797	1.006e-26	115.0	COG3599@1|root,COG3599@2|Bacteria,3J19M@40117|Nitrospirae	40117|Nitrospirae	D	DivIVA protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
MMD1_k127_5126372_12	289376.THEYE_A1798	2.571e-29	119.0	COG0762@1|root,COG0762@2|Bacteria,3J0U5@40117|Nitrospirae	40117|Nitrospirae	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
MMD1_k127_5126372_4	448385.sce5868	1.017e-84	288.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
MMD1_k127_5126372_5	439235.Dalk_0394	1.048e-78	271.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2MJ9P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
MMD1_k127_5126372_7	316067.Geob_1028	1.224e-51	194.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,43TE9@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
MMD1_k127_5126372_1	401526.TcarDRAFT_0567	9.257e-164	533.0	COG1032@1|root,COG1032@2|Bacteria,1TQJT@1239|Firmicutes,4H23J@909932|Negativicutes	909932|Negativicutes	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMD1_k127_5126372_9	1123368.AUIS01000004_gene248	6.85e-47	179.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,2NBQP@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
MMD1_k127_5126372_8	243231.GSU2326	1.684e-50	185.0	COG3040@1|root,COG3040@2|Bacteria,1RIHP@1224|Proteobacteria,42SSW@68525|delta/epsilon subdivisions,2X6M9@28221|Deltaproteobacteria,43VBP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
MMD1_k127_5126372_3	1125863.JAFN01000001_gene3353	2.152e-116	388.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
MMD1_k127_5126372_2	269799.Gmet_0416	5.039e-129	419.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
MMD1_k127_5133333_5	1479237.JMLY01000001_gene3242	1.041e-05	48.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1S65E@1236|Gammaproteobacteria,4681I@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
MMD1_k127_5133333_1	269799.Gmet_0245	3.331e-209	662.0	COG1032@1|root,COG1032@2|Bacteria,1PDZR@1224|Proteobacteria,42M73@68525|delta/epsilon subdivisions,2WK6Y@28221|Deltaproteobacteria,43SAZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD1_k127_5133333_3	580332.Slit_1670	1.215e-84	289.0	COG3439@1|root,COG3439@2|Bacteria,1MXYT@1224|Proteobacteria,2W0RY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5133333_4	1232410.KI421412_gene293	7.378e-19	94.0	COG3043@1|root,COG3043@2|Bacteria,1RG8Q@1224|Proteobacteria,42S2W@68525|delta/epsilon subdivisions,2WNP8@28221|Deltaproteobacteria,43V2D@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	pccJ	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_5133333_0	338966.Ppro_2348	5.87e-273	864.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,43S5U@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
MMD1_k127_5133333_2	608538.HTH_1104	1.451e-121	400.0	COG1858@1|root,COG1858@2|Bacteria,2G4TF@200783|Aquificae	200783|Aquificae	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
MMD1_k127_5140461_11	215803.DB30_1212	1.58e-89	306.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2YXPT@29|Myxococcales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
MMD1_k127_5140461_12	338963.Pcar_1972	2.744e-88	299.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,43SF4@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Quinolinate phosphoribosyl transferase, C-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
MMD1_k127_5140461_13	760568.Desku_3202	3.121e-87	299.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,260CI@186807|Peptococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
MMD1_k127_5140461_10	401526.TcarDRAFT_0920	2.312e-96	321.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H2ZZ@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
MMD1_k127_5140461_19	338966.Ppro_0435	1.968e-32	129.0	COG2204@1|root,COG2204@2|Bacteria,1RKC4@1224|Proteobacteria,42SJ3@68525|delta/epsilon subdivisions,2WPI1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_5140461_8	1162668.LFE_2206	1.66e-122	405.0	COG1085@1|root,COG1085@2|Bacteria,3J0ER@40117|Nitrospirae	40117|Nitrospirae	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
MMD1_k127_5140461_20	1122604.JONR01000003_gene1574	1.05e-28	121.0	COG2940@1|root,COG2940@2|Bacteria,1RIQT@1224|Proteobacteria	1224|Proteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
MMD1_k127_5140461_0	484770.UFO1_0827	7.848e-278	867.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4H2CQ@909932|Negativicutes	909932|Negativicutes	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
MMD1_k127_5140461_17	399550.Smar_0766	1.334e-37	146.0	COG2193@1|root,arCOG01094@2157|Archaea	2157|Archaea	P	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
MMD1_k127_5140461_18	1304888.ATWF01000001_gene2190	2.466e-36	143.0	COG0589@1|root,COG0589@2|Bacteria,2GFI3@200930|Deferribacteres	200930|Deferribacteres	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_5140461_5	330214.NIDE1103	4.637e-138	445.0	COG0115@1|root,COG0115@2|Bacteria,3J0BM@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
MMD1_k127_5140461_22	1499967.BAYZ01000069_gene1847	2.073e-16	93.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3,SPOR
MMD1_k127_5140461_3	443143.GM18_4134	1.247e-211	670.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,43SC2@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
MMD1_k127_5140461_15	156889.Mmc1_3535	2.704e-72	253.0	COG3221@1|root,COG3221@2|Bacteria,1RGMZ@1224|Proteobacteria,2U4RU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
MMD1_k127_5140461_4	443143.GM18_2098	1.247e-142	484.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,dCache_1
MMD1_k127_5140461_21	269799.Gmet_1680	3.153e-20	93.0	2CFNS@1|root,331AJ@2|Bacteria,1NBYG@1224|Proteobacteria,42VZ5@68525|delta/epsilon subdivisions,2WR8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5140461_1	1121920.AUAU01000020_gene2550	3.816e-217	685.0	COG0433@1|root,COG0433@2|Bacteria,3Y69X@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF853
MMD1_k127_5140461_2	316067.Geob_3801	2.679e-216	687.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,43U97@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
MMD1_k127_5140461_7	1158345.JNLL01000001_gene1147	6.464e-129	441.0	COG0604@1|root,COG0604@2|Bacteria,2G4NX@200783|Aquificae	200783|Aquificae	C	Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
MMD1_k127_5140461_14	251229.Chro_1602	7.154e-75	268.0	COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,1GBM2@1117|Cyanobacteria	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
MMD1_k127_5140461_9	639282.DEFDS_0531	1.089e-97	327.0	COG1806@1|root,COG1806@2|Bacteria,2GF8T@200930|Deferribacteres	200930|Deferribacteres	H	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
MMD1_k127_5140461_24	4792.ETI49569	3.346e-10	74.0	COG0666@1|root,KOG0504@2759|Eukaryota,3Q8S7@4776|Peronosporales	4776|Peronosporales	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_5
MMD1_k127_5140461_16	1232437.KL661963_gene3412	4.279e-61	237.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,42TI1@68525|delta/epsilon subdivisions,2WQ9N@28221|Deltaproteobacteria,2MKQG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
MMD1_k127_5140461_6	335543.Sfum_0488	3.463e-131	427.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42N26@68525|delta/epsilon subdivisions,2WK9Q@28221|Deltaproteobacteria,2MR40@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
MMD1_k127_5143358_7	697284.ERIC2_c35770	2.329e-48	184.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26R22@186822|Paenibacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
MMD1_k127_5143358_9	264462.Bd0240	4.395e-38	148.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,42SH8@68525|delta/epsilon subdivisions,2MTEP@213481|Bdellovibrionales,2WQ3S@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
MMD1_k127_5143358_10	398767.Glov_1016	5.648e-16	79.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
MMD1_k127_5143358_1	269799.Gmet_0952	2.079e-110	370.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,43TJH@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
MMD1_k127_5143358_0	269799.Gmet_0608	2.819e-126	415.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,43TEU@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMD1_k127_5143358_8	338963.Pcar_1899	7.47e-48	175.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,43SIQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
MMD1_k127_5143358_6	1118054.CAGW01000091_gene3541	6.684e-55	196.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli,26WTQ@186822|Paenibacillaceae	91061|Bacilli	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
MMD1_k127_5143358_3	316067.Geob_1522	1.255e-104	348.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,43SZ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
MMD1_k127_5143358_4	640510.BC1001_2163	1.323e-86	295.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,1K0QT@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
MMD1_k127_5143358_2	338963.Pcar_1919	7.8e-105	344.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
MMD1_k127_5143358_5	243231.GSU1918	8.27e-58	209.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,43UDS@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
MMD1_k127_5143358_13	1232410.KI421415_gene3097	1.575e-11	70.0	2E20Q@1|root,32X8P@2|Bacteria,1N3P4@1224|Proteobacteria,42TSV@68525|delta/epsilon subdivisions,2WQ7Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5143358_12	525897.Dbac_0718	1.161e-12	73.0	2E20Q@1|root,32X8P@2|Bacteria,1N3P4@1224|Proteobacteria,42TSV@68525|delta/epsilon subdivisions,2WQ7Q@28221|Deltaproteobacteria,2MCZ9@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5143358_11	314345.SPV1_05078	2.799e-15	84.0	COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria	1224|Proteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16,TPR_19,TPR_2,TPR_8
MMD1_k127_5149371_1	1163617.SCD_n02272	1.637e-132	435.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKVT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
MMD1_k127_5149371_5	267377.MMP0303	7.832e-18	84.0	COG1773@1|root,arCOG04391@2157|Archaea,2Y080@28890|Euryarchaeota,23RCD@183939|Methanococci	183939|Methanococci	C	PFAM Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
MMD1_k127_5149371_0	909663.KI867150_gene1859	1.241e-190	605.0	COG0426@1|root,COG0426@2|Bacteria,1NDXY@1224|Proteobacteria,42N11@68525|delta/epsilon subdivisions,2WJ8Z@28221|Deltaproteobacteria,2MQWF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Metallo-beta-lactamase superfamily	roo	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B
MMD1_k127_5149371_2	56780.SYN_02524	1.201e-39	151.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42TU6@68525|delta/epsilon subdivisions,2WPZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
MMD1_k127_5149371_4	338963.Pcar_3130	1.019e-30	126.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,43SJV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
MMD1_k127_5149371_3	289376.THEYE_A0241	1.003e-32	127.0	COG0055@1|root,COG0055@2|Bacteria,3J0BN@40117|Nitrospirae	40117|Nitrospirae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
MMD1_k127_5161159_1	443143.GM18_0042	2.369e-81	278.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,42M7N@68525|delta/epsilon subdivisions,2WM4F@28221|Deltaproteobacteria,43T32@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.10.3.10,1.9.3.1	ko:K02275,ko:K02297	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX2,COX2_TM,COX_ARM,Cytochrom_C,Cytochrome_CBB3
MMD1_k127_5161159_3	1232410.KI421415_gene2987	2.575e-20	94.0	2EAMQ@1|root,334Q9@2|Bacteria,1NA2T@1224|Proteobacteria,42VC9@68525|delta/epsilon subdivisions,2WRD9@28221|Deltaproteobacteria,43SRT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Prokaryotic Cytochrome C oxidase subunit IV	coxD	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
MMD1_k127_5161159_2	945713.IALB_1395	2.682e-68	239.0	COG1845@1|root,COG1845@2|Bacteria	2|Bacteria	C	cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
MMD1_k127_5161159_0	269799.Gmet_0249	1.68e-161	513.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions,2WJUK@28221|Deltaproteobacteria,43S0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1
MMD1_k127_5179765_1	1382315.JPOI01000001_gene1632	5.265e-51	190.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli,1WEKT@129337|Geobacillus	91061|Bacilli	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
MMD1_k127_5179765_0	338963.Pcar_1689	1.885e-95	316.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2WK74@28221|Deltaproteobacteria,43S5T@69541|Desulfuromonadales	28221|Deltaproteobacteria	OU	Clp protease	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
MMD1_k127_5179765_2	883081.HMPREF9698_00283	1.929e-08	56.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,27FU5@186828|Carnobacteriaceae	91061|Bacilli	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
MMD1_k127_5183205_1	635013.TherJR_2693	4.975e-211	677.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,2634J@186807|Peptococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
MMD1_k127_5183205_3	1125863.JAFN01000001_gene2511	4.656e-28	118.0	COG2050@1|root,COG2050@2|Bacteria,1N8F8@1224|Proteobacteria,42V78@68525|delta/epsilon subdivisions,2WRBA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
MMD1_k127_5183205_0	671143.DAMO_1057	4.3e-226	736.0	COG1391@1|root,COG1391@2|Bacteria	2|Bacteria	H	[glutamate-ammonia-ligase] adenylyltransferase activity	glnE	GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
MMD1_k127_5183205_2	765912.Thimo_0411	4.177e-71	249.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1WVUX@135613|Chromatiales	135613|Chromatiales	M	Lipid A biosynthesis	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
MMD1_k127_5188353_3	292563.Cyast_2521	2.188e-22	102.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
MMD1_k127_5188353_2	330214.NIDE2578	3.826e-68	247.0	2F9RH@1|root,3421I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5188353_0	1123376.AUIU01000016_gene233	1.116e-188	599.0	COG2204@1|root,COG2204@2|Bacteria,3J0ZU@40117|Nitrospirae	40117|Nitrospirae	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_5188353_4	1123376.AUIU01000016_gene232	1.235e-18	91.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,FKBP_N
MMD1_k127_5188353_1	1123376.AUIU01000016_gene231	3.434e-134	442.0	COG5002@1|root,COG5002@2|Bacteria,3J10G@40117|Nitrospirae	40117|Nitrospirae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
MMD1_k127_5188353_5	1120985.AUMI01000017_gene2639	6.698e-14	75.0	COG1251@1|root,COG1251@2|Bacteria,1VKDD@1239|Firmicutes,4H5WA@909932|Negativicutes	909932|Negativicutes	C	2Fe-2S -binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
MMD1_k127_5236519_11	289376.THEYE_A1553	6.021e-26	111.0	COG0640@1|root,COG1693@1|root,COG0640@2|Bacteria,COG1693@2|Bacteria	2|Bacteria	K	Ribonuclease R winged-helix domain protein	-	-	-	ko:K09720	-	-	-	-	ko00000,ko03000	-	-	-	DUF128,HTH_12
MMD1_k127_5236519_1	289376.THEYE_A1850	2.054e-280	868.0	COG1304@1|root,COG1304@2|Bacteria	2|Bacteria	C	FMN binding	yahG	-	-	-	-	-	-	-	-	-	-	-	DUF1116,FMN_dh,Glu_synthase
MMD1_k127_5236519_0	931626.Awo_c07580	1.226e-292	903.0	COG2070@1|root,COG2070@2|Bacteria,1UJNK@1239|Firmicutes,25F6P@186801|Clostridia	186801|Clostridia	S	PFAM ferredoxin-dependent glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
MMD1_k127_5236519_6	289376.THEYE_A1849	4.546e-116	387.0	COG0467@1|root,COG1396@1|root,COG1917@1|root,COG0467@2|Bacteria,COG1396@2|Bacteria,COG1917@2|Bacteria,3J0VE@40117|Nitrospirae	40117|Nitrospirae	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
MMD1_k127_5236519_9	557598.LHK_03104	7.291e-27	110.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,2KS1I@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
MMD1_k127_5236519_8	1521187.JPIM01000023_gene795	6.714e-45	170.0	COG0664@1|root,COG0664@2|Bacteria,2G8WB@200795|Chloroflexi	200795|Chloroflexi	K	Bacterial regulatory proteins, crp family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2
MMD1_k127_5236519_2	1125863.JAFN01000001_gene1963	3.011e-232	732.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
MMD1_k127_5236519_13	1125863.JAFN01000001_gene3406	6.769e-07	56.0	COG2905@1|root,COG2905@2|Bacteria,1R0B9@1224|Proteobacteria,43CTI@68525|delta/epsilon subdivisions,2X8MP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	cNMP_binding
MMD1_k127_5236519_7	1123368.AUIS01000024_gene944	1.467e-54	208.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,1S884@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
MMD1_k127_5236519_5	671143.DAMO_2704	1.648e-133	441.0	COG1007@1|root,COG1007@2|Bacteria,2NNMY@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMD1_k127_5236519_4	330214.NIDE0603	1.223e-180	578.0	COG1008@1|root,COG1008@2|Bacteria,3J0EQ@40117|Nitrospirae	40117|Nitrospirae	C	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
MMD1_k127_5236519_12	517418.Ctha_0005	1.885e-23	109.0	28RU1@1|root,2ZE6D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5236519_3	706587.Desti_2759	9.145e-206	658.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2MS08@213462|Syntrophobacterales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
MMD1_k127_5236519_10	1211777.BN77_p10185	2.594e-26	110.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2USHW@28211|Alphaproteobacteria,4BFGN@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK2	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
MMD1_k127_5243227_0	330214.NIDE1303	9.665e-207	654.0	COG0085@1|root,COG0085@2|Bacteria,3J0CW@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
MMD1_k127_5253868_3	1397527.Q670_14575	4.957e-10	72.0	COG4447@1|root,COG4447@2|Bacteria,1QXK5@1224|Proteobacteria,1T3DJ@1236|Gammaproteobacteria,1XRU6@135619|Oceanospirillales	135619|Oceanospirillales	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5253868_1	1177179.A11A3_00015	1.858e-30	128.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1XKMI@135619|Oceanospirillales	135619|Oceanospirillales	CO	Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
MMD1_k127_5253868_2	1123376.AUIU01000011_gene1017	2.56e-27	115.0	2C5I4@1|root,33FNH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5253868_0	243231.GSU2937	1.344e-90	306.0	293RH@1|root,2ZR74@2|Bacteria,1RGTJ@1224|Proteobacteria,42RWW@68525|delta/epsilon subdivisions,2WNTI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
MMD1_k127_5269558_2	56780.SYN_02953	2.654e-49	177.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NMZ@68525|delta/epsilon subdivisions,2WIZ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
MMD1_k127_5269558_1	1229172.JQFA01000002_gene4544	2.71e-82	280.0	COG1940@1|root,COG1940@2|Bacteria,1G0YU@1117|Cyanobacteria,1H786@1150|Oscillatoriales	1117|Cyanobacteria	GK	Transcriptional regulator sugar kinase	ppgK	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
MMD1_k127_5269558_0	1210884.HG799475_gene15269	3.052e-213	669.0	COG0033@1|root,COG0033@2|Bacteria,2IYG0@203682|Planctomycetes	203682|Planctomycetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMD1_k127_5277123_5	292459.STH876	2.473e-26	115.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,24J85@186801|Clostridia	186801|Clostridia	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
MMD1_k127_5277123_7	443143.GM18_0715	6.699e-21	97.0	2DP14@1|root,3303I@2|Bacteria,1N7JW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5277123_3	443143.GM18_0716	4.117e-54	195.0	2CESE@1|root,32S0D@2|Bacteria,1RHTD@1224|Proteobacteria	1224|Proteobacteria	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
MMD1_k127_5277123_1	888727.HMPREF9092_1224	1.854e-94	321.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3WCD8@538999|Clostridiales incertae sedis	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
MMD1_k127_5277123_2	1173025.GEI7407_3551	1.467e-54	208.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	ydaO2	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMD1_k127_5277123_4	909663.KI867150_gene2665	5.227e-42	171.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1Q3D5@1224|Proteobacteria,42X4J@68525|delta/epsilon subdivisions,2WSZ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
MMD1_k127_5277123_0	316067.Geob_1337	6.156e-165	527.0	COG3746@1|root,COG3746@2|Bacteria,1QXPF@1224|Proteobacteria,42TW0@68525|delta/epsilon subdivisions,2WQ4G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
MMD1_k127_5315130_1	586416.GZ22_09480	2.427e-79	273.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli	91061|Bacilli	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
MMD1_k127_5315130_3	1499967.BAYZ01000156_gene561	8.141e-34	134.0	COG0789@1|root,COG0789@2|Bacteria,2NPTR@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, MerR family	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
MMD1_k127_5315130_0	671143.DAMO_1073	0.0	1153.0	COG0542@1|root,COG0542@2|Bacteria,2NNNE@2323|unclassified Bacteria	2|Bacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
MMD1_k127_5315130_2	96561.Dole_1741	3.967e-45	179.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria,2MMKQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
MMD1_k127_5315130_4	760568.Desku_2909	6.438e-10	64.0	2DSKT@1|root,33GJ4@2|Bacteria,1VKB9@1239|Firmicutes,24VAK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5315130_5	1276756.AUEX01000002_gene434	7.407e-09	57.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,4AB7Z@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
MMD1_k127_5315560_22	96561.Dole_0008	1.683e-10	68.0	COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria,2MIFQ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
MMD1_k127_5315560_20	1123376.AUIU01000011_gene1029	6.155e-12	70.0	COG2952@1|root,COG2952@2|Bacteria,3J1ED@40117|Nitrospirae	40117|Nitrospirae	S	Protein of unknown function (DUF507)	-	-	-	-	-	-	-	-	-	-	-	-	DUF507
MMD1_k127_5315560_21	1232410.KI421426_gene1386	2.061e-11	69.0	COG2952@1|root,COG2952@2|Bacteria,1NKWU@1224|Proteobacteria,42XJT@68525|delta/epsilon subdivisions,2WSNN@28221|Deltaproteobacteria,43SST@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF507)	-	-	-	-	-	-	-	-	-	-	-	-	DUF507
MMD1_k127_5315560_9	1313304.CALK_1933	9.512e-54	214.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,HDOD,PAS_3,PAS_4,PilJ
MMD1_k127_5315560_14	1499967.BAYZ01000147_gene716	1.351e-34	141.0	COG1595@1|root,COG1595@2|Bacteria,2NPR9@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
MMD1_k127_5315560_24	222534.KB893750_gene4397	0.0003313	51.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4ETKR@85013|Frankiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
MMD1_k127_5315560_23	671143.DAMO_2843	2.613e-06	56.0	2DGXT@1|root,2ZXPG@2|Bacteria,2NRPI@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5315560_18	1232410.KI421421_gene3779	5.319e-16	87.0	COG0727@1|root,COG0727@2|Bacteria,1REPM@1224|Proteobacteria,42RPZ@68525|delta/epsilon subdivisions,2WNSE@28221|Deltaproteobacteria,43UMY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
MMD1_k127_5315560_13	1123376.AUIU01000011_gene1021	1.737e-40	156.0	COG0494@1|root,COG0494@2|Bacteria,3J0TN@40117|Nitrospirae	40117|Nitrospirae	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
MMD1_k127_5315560_0	247490.KSU1_C1682	5.998e-252	788.0	COG0058@1|root,COG0058@2|Bacteria,2IY0J@203682|Planctomycetes	203682|Planctomycetes	G	COG0058 Glucan phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphorylase
MMD1_k127_5315560_6	443143.GM18_2270	1.024e-112	381.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
MMD1_k127_5315560_5	404380.Gbem_0080	8.305e-133	432.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
MMD1_k127_5315560_10	335543.Sfum_1685	1.366e-53	192.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria,2MQJ3@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
MMD1_k127_5315560_17	402777.KB235903_gene1816	7.832e-18	84.0	2AFHA@1|root,315HT@2|Bacteria,1G5WD@1117|Cyanobacteria,1HBUI@1150|Oscillatoriales	1117|Cyanobacteria	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMD1_k127_5315560_19	865938.Weevi_0619	3.026e-12	70.0	2AFHA@1|root,315HT@2|Bacteria,4NQ5F@976|Bacteroidetes,1I2SM@117743|Flavobacteriia	976|Bacteroidetes	S	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
MMD1_k127_5315560_15	479434.Sthe_1164	9.103e-28	117.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi,27YGT@189775|Thermomicrobia	189775|Thermomicrobia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
MMD1_k127_5315560_12	443143.GM18_4222	4.003e-41	156.0	COG3305@1|root,COG3305@2|Bacteria,1RKBI@1224|Proteobacteria	1224|Proteobacteria	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
MMD1_k127_5315560_16	1144275.COCOR_03122	3.09e-22	100.0	COG3832@1|root,COG5646@1|root,COG3832@2|Bacteria,COG5646@2|Bacteria,1NKMZ@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,DUF1801
MMD1_k127_5315560_1	349161.Dred_2987	1.784e-196	621.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,2600A@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
MMD1_k127_5315560_2	316067.Geob_3051	2.815e-171	549.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria,43STX@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
MMD1_k127_5315560_11	555088.DealDRAFT_0314	2.482e-45	168.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,42K6X@68298|Syntrophomonadaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
MMD1_k127_5315560_4	269799.Gmet_1913	2.615e-142	463.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,43TYY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
MMD1_k127_5315560_3	269799.Gmet_0109	5.693e-158	508.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2WKJ2@28221|Deltaproteobacteria,43S3B@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
MMD1_k127_5315560_7	1167006.UWK_00372	1.021e-81	285.0	COG2206@1|root,COG2206@2|Bacteria,1RE2G@1224|Proteobacteria,42S6Z@68525|delta/epsilon subdivisions,2WNCP@28221|Deltaproteobacteria,2MNN1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
MMD1_k127_5315560_8	269799.Gmet_2816	3.183e-69	262.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,43TQ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
MMD1_k127_5318617_3	247490.KSU1_C1013	1.676e-46	175.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	yvkB	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	Phage_integrase,TetR_C_11,TetR_N
MMD1_k127_5318617_1	56780.SYN_02462	7.63e-107	367.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,42S0Z@68525|delta/epsilon subdivisions,2X5KP@28221|Deltaproteobacteria,2MRDS@213462|Syntrophobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD1_k127_5318617_2	247490.KSU1_C1014	1.331e-101	344.0	COG0845@1|root,COG0845@2|Bacteria,2IZDC@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
MMD1_k127_5318617_0	247490.KSU1_C0704	0.0	1294.0	COG0841@1|root,COG0841@2|Bacteria,2IY6W@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07788	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
MMD1_k127_5331643_5	649747.HMPREF0083_03412	3.259e-48	193.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,4HDJQ@91061|Bacilli,26WY4@186822|Paenibacillaceae	91061|Bacilli	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	cckA	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS_9,Response_reg,dCache_1
MMD1_k127_5331643_1	456442.Mboo_2111	1.412e-92	314.0	COG0715@1|root,arCOG01803@2157|Archaea,2XWEK@28890|Euryarchaeota,2NAA1@224756|Methanomicrobia	224756|Methanomicrobia	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
MMD1_k127_5331643_2	243090.RB8978	8.237e-74	258.0	COG1235@1|root,COG1235@2|Bacteria,2IZQK@203682|Planctomycetes	203682|Planctomycetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
MMD1_k127_5331643_3	243231.GSU2756	2.293e-57	208.0	COG0484@1|root,COG0484@2|Bacteria,1N40E@1224|Proteobacteria,42UFJ@68525|delta/epsilon subdivisions,2X2DV@28221|Deltaproteobacteria,43UV5@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5331643_4	1125863.JAFN01000001_gene3104	1.63e-52	191.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,42SK4@68525|delta/epsilon subdivisions,2WPI8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	iorB-1	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
MMD1_k127_5331643_0	1121918.ARWE01000001_gene3607	1.92e-108	359.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
MMD1_k127_5338110_0	706587.Desti_4478	4.915e-89	304.0	COG0577@1|root,COG0577@2|Bacteria,1R6DP@1224|Proteobacteria,42PWX@68525|delta/epsilon subdivisions,2WJSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
MMD1_k127_5338110_1	243231.GSU1341	8.2e-75	262.0	COG1136@1|root,COG1136@2|Bacteria,1Q3QX@1224|Proteobacteria,42NVX@68525|delta/epsilon subdivisions,2X5TP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
MMD1_k127_5338110_2	237368.SCABRO_00286	1.281e-30	121.0	COG0614@1|root,COG0614@2|Bacteria,2J0J0@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
MMD1_k127_5338110_3	237368.SCABRO_00286	4.272e-10	63.0	COG0614@1|root,COG0614@2|Bacteria,2J0J0@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
MMD1_k127_5338110_4	378806.STAUR_3289	1.694e-05	53.0	2A42Z@1|root,30SMX@2|Bacteria,1PBWJ@1224|Proteobacteria,4385D@68525|delta/epsilon subdivisions,2X3FD@28221|Deltaproteobacteria,2YVUP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5377407_0	335543.Sfum_0673	0.0	1080.0	COG3408@1|root,COG3408@2|Bacteria,1QUN2@1224|Proteobacteria,42PYS@68525|delta/epsilon subdivisions,2WMEG@28221|Deltaproteobacteria,2MRGX@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
MMD1_k127_5377407_3	1232410.KI421426_gene1483	1.953e-45	171.0	29WX2@1|root,30IJ3@2|Bacteria,1Q0W8@1224|Proteobacteria,433PA@68525|delta/epsilon subdivisions,2WXEY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cysteine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_FGFR
MMD1_k127_5377407_2	631362.Thi970DRAFT_01797	2.683e-50	190.0	COG2067@1|root,COG2067@2|Bacteria,1RJIQ@1224|Proteobacteria,1SAC1@1236|Gammaproteobacteria,1WZ89@135613|Chromatiales	135613|Chromatiales	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5377407_1	234267.Acid_4507	6.041e-72	247.0	COG0366@1|root,COG0366@2|Bacteria,3Y2P1@57723|Acidobacteria	57723|Acidobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
MMD1_k127_5435237_2	909663.KI867150_gene658	3.247e-89	297.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2MQRF@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
MMD1_k127_5435237_4	1227739.Hsw_0390	5.7e-08	64.0	COG0642@1|root,COG0642@2|Bacteria,4NJVF@976|Bacteroidetes,47Y2W@768503|Cytophagia	976|Bacteroidetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Reg_prop,Response_reg
MMD1_k127_5435237_3	909663.KI867150_gene1017	4.918e-43	160.0	COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,430JJ@68525|delta/epsilon subdivisions,2WVQQ@28221|Deltaproteobacteria,2MRZH@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
MMD1_k127_5435237_1	644966.Tmar_0092	8.552e-109	364.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WCTC@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
MMD1_k127_5435237_0	909663.KI867150_gene2148	5.512e-252	802.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MQ8R@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
MMD1_k127_5494915_9	575540.Isop_1236	8.17e-49	184.0	COG3527@1|root,COG3527@2|Bacteria,2J4RG@203682|Planctomycetes	203682|Planctomycetes	Q	Alpha-acetolactate decarboxylase	-	-	4.1.1.5	ko:K01575	ko00650,ko00660,map00650,map00660	-	R02948	RC00812	ko00000,ko00001,ko01000	-	-	-	-
MMD1_k127_5494915_4	767817.Desgi_2793	2.318e-121	398.0	COG0730@1|root,COG0730@2|Bacteria,1TST0@1239|Firmicutes,24B4S@186801|Clostridia,260G8@186807|Peptococcaceae	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_5494915_2	671143.DAMO_0410	1.852e-258	810.0	COG2060@1|root,COG2060@2|Bacteria,2NP13@2323|unclassified Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAPECO1_1312.APECO1_1369,iECUMN_1333.ECUMN_0780,iYL1228.KPN_00717	KdpA
MMD1_k127_5494915_1	1192034.CAP_6024	3.479e-319	990.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,42NGX@68525|delta/epsilon subdivisions,2WJC0@28221|Deltaproteobacteria,2YWXY@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAF987.Gmet_2434	E1-E2_ATPase,Hydrolase
MMD1_k127_5494915_7	1234364.AMSF01000016_gene1734	2.713e-68	237.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,1S2B0@1236|Gammaproteobacteria,1X6DA@135614|Xanthomonadales	135614|Xanthomonadales	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
MMD1_k127_5494915_12	443143.GM18_2411	2.869e-12	72.0	2CCGA@1|root,343UD@2|Bacteria,1P3JZ@1224|Proteobacteria,43123@68525|delta/epsilon subdivisions,2WWQS@28221|Deltaproteobacteria,43VIT@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5494915_0	671143.DAMO_0414	0.0	1031.0	COG0642@1|root,COG2205@2|Bacteria,2NNNV@2323|unclassified Bacteria	2|Bacteria	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
MMD1_k127_5494915_6	1254432.SCE1572_09230	3.611e-97	325.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria,2YXCH@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
MMD1_k127_5494915_3	1304872.JAGC01000003_gene2537	7.463e-251	790.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
MMD1_k127_5494915_8	1121434.AULY01000007_gene1623	8.782e-53	208.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2M8UQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,sCache_3_2
MMD1_k127_5494915_5	56780.SYN_02538	1.999e-97	322.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria,2MQS9@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Adenylate kinase, active site lid	adk	GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
MMD1_k127_5494915_10	338963.Pcar_1411	4.579e-23	105.0	COG2199@1|root,COG3706@2|Bacteria,1MZZV@1224|Proteobacteria,42UXH@68525|delta/epsilon subdivisions,2WVP3@28221|Deltaproteobacteria,43SMM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver domain	cheY40H-4	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
MMD1_k127_5494915_11	290315.Clim_1721	6.057e-17	80.0	COG0107@1|root,COG0107@2|Bacteria,1FDR8@1090|Chlorobi	1090|Chlorobi	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMD1_k127_5496121_2	522306.CAP2UW1_3400	5.755e-13	71.0	COG2995@1|root,COG2995@2|Bacteria,1RAQ9@1224|Proteobacteria,2VQ5G@28216|Betaproteobacteria,1KR1C@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
MMD1_k127_5496121_3	438753.AZC_0167	1.827e-07	59.0	2DIBA@1|root,302MG@2|Bacteria,1NGIQ@1224|Proteobacteria,2V04D@28211|Alphaproteobacteria,3F05H@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Cysteine rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_FGFR
MMD1_k127_5496121_1	404589.Anae109_2842	2.057e-37	149.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
MMD1_k127_5496121_0	909663.KI867149_gene3179	7.457e-130	418.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,42PD2@68525|delta/epsilon subdivisions,2WJIK@28221|Deltaproteobacteria,2MR97@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
MMD1_k127_5510590_0	289376.THEYE_A1471	1.827e-146	477.0	COG1456@1|root,COG1456@2|Bacteria	2|Bacteria	C	acetyl-CoA catabolic process	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
MMD1_k127_5510590_1	289376.THEYE_A1472	1.704e-52	188.0	COG2069@1|root,COG2069@2|Bacteria	2|Bacteria	C	one-carbon metabolic process	acsD	-	1.2.7.4,2.1.1.245	ko:K00194,ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R07157,R08034,R09096,R10219,R10243	RC00004,RC00113,RC00250,RC02800,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
MMD1_k127_5529230_2	546414.Deide_03150	5.169e-23	101.0	COG0697@1|root,COG0697@2|Bacteria,1WJTG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
MMD1_k127_5529230_1	338966.Ppro_3001	3.027e-43	167.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2WPAC@28221|Deltaproteobacteria,43UU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
MMD1_k127_5529230_3	1007103.AFHW01000021_gene251	1.822e-11	70.0	COG4314@1|root,COG4314@2|Bacteria,1V86E@1239|Firmicutes,4HJXZ@91061|Bacilli,26XS8@186822|Paenibacillaceae	91061|Bacilli	C	NosL	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
MMD1_k127_5529230_0	443143.GM18_2454	1.175e-67	236.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria,43VWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	ATP synthase subunit D	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
MMD1_k127_5541783_0	1121405.dsmv_2131	8.528e-104	347.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2MJ4T@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
MMD1_k127_5541783_2	316067.Geob_3388	9.835e-36	140.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
MMD1_k127_5541783_1	316067.Geob_3387	5.188e-44	165.0	COG0745@1|root,COG0745@2|Bacteria,1R9AR@1224|Proteobacteria,42YHD@68525|delta/epsilon subdivisions,2WU58@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
MMD1_k127_5584707_0	289376.THEYE_A0342	1.016e-128	417.0	COG0436@1|root,COG0436@2|Bacteria,3J0EV@40117|Nitrospirae	40117|Nitrospirae	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD1_k127_5607230_1	1519464.HY22_08900	7.459e-63	228.0	COG0679@1|root,COG0679@2|Bacteria	2|Bacteria	S	auxin-activated signaling pathway	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
MMD1_k127_5607230_0	909663.KI867150_gene2218	2.291e-78	274.0	COG1820@1|root,COG1820@2|Bacteria,1MW8Y@1224|Proteobacteria,430VJ@68525|delta/epsilon subdivisions,2WVQI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
MMD1_k127_5607230_2	1131269.AQVV01000020_gene2207	4.852e-21	97.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase_like
MMD1_k127_5630828_0	1249480.B649_01585	8.366e-14	75.0	COG4679@1|root,COG4679@2|Bacteria	1249480.B649_01585|-	K	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5630828_1	880073.Calab_1937	2.318e-12	72.0	2DRJZ@1|root,33C4Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_5663504_7	338963.Pcar_1049	1.698e-63	220.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,43SBN@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMD1_k127_5663504_8	589865.DaAHT2_1934	7.305e-40	158.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
MMD1_k127_5663504_10	999423.HMPREF9161_00178	2.9e-06	56.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,4H4Q7@909932|Negativicutes	909932|Negativicutes	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
MMD1_k127_5663504_2	330214.NIDE1016	5.594e-151	499.0	COG0768@1|root,COG0768@2|Bacteria,3J0FY@40117|Nitrospirae	40117|Nitrospirae	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMD1_k127_5663504_4	589865.DaAHT2_1937	2.553e-91	314.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2MJ4R@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
MMD1_k127_5663504_1	1232410.KI421426_gene1341	6.737e-223	717.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,43RXX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
MMD1_k127_5663504_3	580327.Tthe_0257	4.611e-122	404.0	COG0477@1|root,COG0477@2|Bacteria,1UI7B@1239|Firmicutes,25ECI@186801|Clostridia,42J7J@68295|Thermoanaerobacterales	186801|Clostridia	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
MMD1_k127_5663504_5	1134912.AJTV01000034_gene2311	2.003e-69	244.0	COG4689@1|root,COG4689@2|Bacteria,1R7YD@1224|Proteobacteria	1224|Proteobacteria	Q	Acetoacetate decarboxylase (ADC)	-	-	-	-	-	-	-	-	-	-	-	-	ADC
MMD1_k127_5663504_9	234267.Acid_5474	1.366e-33	138.0	COG4276@1|root,COG4276@2|Bacteria,3Y57N@57723|Acidobacteria	57723|Acidobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
MMD1_k127_5663504_6	266117.Rxyl_0489	8.933e-66	231.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CQI8@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
MMD1_k127_5663504_0	1121440.AUMA01000011_gene2309	0.0	1114.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2M7WE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
MMD1_k127_5685509_6	243231.GSU3383	1.591e-29	122.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,43V4D@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
MMD1_k127_5685509_5	330214.NIDE2919	3.571e-45	166.0	COG0853@1|root,COG0853@2|Bacteria,3J0Q2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
MMD1_k127_5685509_0	671143.DAMO_0810	1.748e-207	655.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
MMD1_k127_5685509_1	880072.Desac_0997	3.525e-196	621.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2MQ8D@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
MMD1_k127_5685509_7	398579.Spea_2677	8.068e-17	89.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,2Q9NI@267890|Shewanellaceae	1236|Gammaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	ppiD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
MMD1_k127_5685509_2	1144275.COCOR_06542	6.523e-167	537.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria,2YUYT@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
MMD1_k127_5685509_3	404380.Gbem_3366	1.018e-94	325.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
MMD1_k127_5685509_4	56780.SYN_00561	5.362e-62	220.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2MQEQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
MMD1_k127_5821919_4	439235.Dalk_5198	2.012e-16	87.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,42UMQ@68525|delta/epsilon subdivisions,2WQY1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
MMD1_k127_5821919_2	289376.THEYE_A1821	2.046e-41	154.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
MMD1_k127_5821919_0	880073.Calab_2028	3.893e-99	331.0	COG2084@1|root,COG2084@2|Bacteria,2NP96@2323|unclassified Bacteria	2|Bacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
MMD1_k127_5821919_3	1173027.Mic7113_1696	3.225e-37	144.0	COG2852@1|root,COG2852@2|Bacteria,1G6T3@1117|Cyanobacteria,1HBZY@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
MMD1_k127_5821919_1	204669.Acid345_2295	2.994e-83	283.0	COG2252@1|root,COG2252@2|Bacteria,3Y2I3@57723|Acidobacteria,2JIGY@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease family	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
MMD1_k127_593014_2	1452718.JBOY01000002_gene469	3.399e-05	52.0	2F5BY@1|root,33XY2@2|Bacteria,1NWB1@1224|Proteobacteria,1SPDS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
MMD1_k127_593014_0	96561.Dole_3193	1.043e-99	346.0	COG2199@1|root,COG3850@1|root,COG2199@2|Bacteria,COG3850@2|Bacteria,1NT1K@1224|Proteobacteria,42R1P@68525|delta/epsilon subdivisions,2WN0S@28221|Deltaproteobacteria,2MMVQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
MMD1_k127_593014_1	1232410.KI421422_gene2016	1.813e-50	184.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,43S7U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transglycosylase	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
MMD1_k127_597934_12	1131269.AQVV01000004_gene587	7.568e-64	223.0	COG0107@1|root,COG0107@2|Bacteria	2|Bacteria	E	imidazoleglycerol-phosphate synthase activity	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
MMD1_k127_597934_16	1049564.TevJSym_ao00390	2.35e-21	106.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,1SGEP@1236|Gammaproteobacteria,1JBHN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM VanZ	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
MMD1_k127_597934_7	338966.Ppro_3056	3.427e-99	329.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2WK1K@28221|Deltaproteobacteria,43SU7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0388	His_biosynth
MMD1_k127_597934_9	243231.GSU3097	6.635e-88	295.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WMNR@28221|Deltaproteobacteria,43TGC@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
MMD1_k127_597934_10	338963.Pcar_2687	1.553e-79	270.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2WNA4@28221|Deltaproteobacteria,43S0D@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
MMD1_k127_597934_8	349521.HCH_05304	4.062e-89	306.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1XH6X@135619|Oceanospirillales	135619|Oceanospirillales	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD1_k127_597934_5	289376.THEYE_A0436	7.302e-126	410.0	COG0040@1|root,COG0040@2|Bacteria,3J0T5@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
MMD1_k127_597934_3	443144.GM21_3799	8.914e-156	502.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
MMD1_k127_597934_1	1232410.KI421412_gene109	4.971e-170	546.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,43TD6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
MMD1_k127_597934_13	240015.ACP_2650	2.569e-59	218.0	COG2890@1|root,COG2890@2|Bacteria,3Y4KU@57723|Acidobacteria,2JJCF@204432|Acidobacteriia	204432|Acidobacteriia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
MMD1_k127_597934_4	1123376.AUIU01000018_gene18	3.402e-145	469.0	COG0216@1|root,COG0216@2|Bacteria,3J0F6@40117|Nitrospirae	40117|Nitrospirae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
MMD1_k127_597934_6	243231.GSU3105	4.728e-103	346.0	COG3872@1|root,COG3872@2|Bacteria,1RCB0@1224|Proteobacteria,42R3I@68525|delta/epsilon subdivisions,2WMZR@28221|Deltaproteobacteria,43U2U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
MMD1_k127_597934_14	1120971.AUCA01000008_gene1945	7.017e-25	106.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli	91061|Bacilli	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
MMD1_k127_597934_0	330214.NIDE0975	1.404e-212	667.0	COG1158@1|root,COG1158@2|Bacteria,3J0BK@40117|Nitrospirae	40117|Nitrospirae	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
MMD1_k127_597934_15	690850.Desaf_2410	3.971e-24	111.0	COG0457@1|root,COG0457@2|Bacteria,1N0Q1@1224|Proteobacteria,42TBT@68525|delta/epsilon subdivisions,2WQ96@28221|Deltaproteobacteria,2MCPE@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
MMD1_k127_597934_11	1123242.JH636435_gene2942	1.491e-70	253.0	2E79V@1|root,331TF@2|Bacteria,2J35R@203682|Planctomycetes	203682|Planctomycetes	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
MMD1_k127_597934_2	1288494.EBAPG3_29340	1.078e-157	506.0	COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1MV8J@1224|Proteobacteria,2W9NC@28216|Betaproteobacteria,3726J@32003|Nitrosomonadales	28216|Betaproteobacteria	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
MMD1_k127_598982_0	552811.Dehly_0886	3.078e-110	369.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi,34DQQ@301297|Dehalococcoidia	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMD1_k127_598982_2	351160.RCIX79	1.592e-10	63.0	COG1249@1|root,arCOG01068@2157|Archaea,2XTJE@28890|Euryarchaeota,2N9NV@224756|Methanomicrobia	224756|Methanomicrobia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
MMD1_k127_598982_1	1417296.U879_07455	1.227e-11	70.0	2BZQB@1|root,32Y98@2|Bacteria,1R3P4@1224|Proteobacteria,2UFWD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_599537_2	926562.Oweho_3009	3.039e-38	157.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMD1_k127_599537_4	1191523.MROS_2413	5.847e-10	61.0	2CG1Y@1|root,2Z9QX@2|Bacteria	2|Bacteria	S	COG NOG19146 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
MMD1_k127_599537_5	243231.GSU2713	6.424e-05	50.0	2CG1Y@1|root,32WID@2|Bacteria,1N01A@1224|Proteobacteria,42UK0@68525|delta/epsilon subdivisions,2WQED@28221|Deltaproteobacteria,43SMQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573,PapD-like
MMD1_k127_599537_3	671143.DAMO_3013	5.071e-25	114.0	COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
MMD1_k127_599537_0	1125863.JAFN01000001_gene920	5.667e-84	286.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
MMD1_k127_599537_1	515635.Dtur_1383	1.663e-50	184.0	COG0209@1|root,COG0209@2|Bacteria	2|Bacteria	F	ribonucleoside-diphosphate reductase activity	nrdZ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
MMD1_k127_61277_27	330214.NIDE0999	5.866e-31	122.0	COG0059@1|root,COG0059@2|Bacteria,3J0DW@40117|Nitrospirae	40117|Nitrospirae	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
MMD1_k127_61277_20	1131269.AQVV01000018_gene1893	8.589e-65	228.0	COG0688@1|root,COG0688@2|Bacteria	2|Bacteria	I	phosphatidylethanolamine metabolic process	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
MMD1_k127_61277_21	289376.THEYE_A0651	3.137e-64	228.0	COG1183@1|root,COG1183@2|Bacteria,3J0KW@40117|Nitrospirae	40117|Nitrospirae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
MMD1_k127_61277_1	330214.NIDE1002	2.902e-230	722.0	COG0119@1|root,COG0119@2|Bacteria,3J0F7@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
MMD1_k127_61277_2	1123376.AUIU01000011_gene1001	3.239e-201	634.0	COG0065@1|root,COG0065@2|Bacteria,3J0IH@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
MMD1_k127_61277_16	1125863.JAFN01000001_gene2477	3.333e-79	269.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42R6H@68525|delta/epsilon subdivisions,2X5ND@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
MMD1_k127_61277_6	665571.STHERM_c03940	3.783e-177	561.0	COG0473@1|root,COG0473@2|Bacteria	2|Bacteria	CE	3-isopropylmalate dehydrogenase activity	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
MMD1_k127_61277_3	1452718.JBOY01000042_gene1870	2.261e-180	571.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMD1_k127_61277_8	289376.THEYE_A0113	1.387e-150	482.0	COG0136@1|root,COG0136@2|Bacteria,3J0BR@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
MMD1_k127_61277_26	565033.GACE_0099	2.779e-38	154.0	arCOG06549@1|root,arCOG06549@2157|Archaea,2Y31C@28890|Euryarchaeota,246R3@183980|Archaeoglobi	183980|Archaeoglobi	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
MMD1_k127_61277_33	1410650.JHWL01000006_gene1425	4.733e-05	48.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,4BX0G@830|Butyrivibrio	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_26,HTH_3
MMD1_k127_61277_11	269799.Gmet_0697	6.301e-88	297.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
MMD1_k127_61277_9	316067.Geob_0754	1.802e-103	349.0	COG1145@1|root,COG2006@1|root,COG1145@2|Bacteria,COG2006@2|Bacteria,1RABP@1224|Proteobacteria,42QQA@68525|delta/epsilon subdivisions,2WMRX@28221|Deltaproteobacteria,43U50@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
MMD1_k127_61277_28	316067.Geob_0969	9.809e-30	130.0	2DE9Y@1|root,2ZM4N@2|Bacteria,1Q17X@1224|Proteobacteria,43756@68525|delta/epsilon subdivisions,2X21C@28221|Deltaproteobacteria,43SFZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_61277_17	330214.NIDE2766	1.709e-71	261.0	COG1403@1|root,COG1403@2|Bacteria,3J0VM@40117|Nitrospirae	40117|Nitrospirae	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
MMD1_k127_61277_29	1379698.RBG1_1C00001G1750	5.763e-17	87.0	COG0457@1|root,COG0457@2|Bacteria,2NRMR@2323|unclassified Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
MMD1_k127_61277_31	1265505.ATUG01000001_gene3995	4.068e-11	72.0	29DP0@1|root,300KT@2|Bacteria,1RDQM@1224|Proteobacteria,42S25@68525|delta/epsilon subdivisions,2WNNJ@28221|Deltaproteobacteria,2MJZ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
MMD1_k127_61277_18	643648.Slip_0842	2.816e-71	250.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,42JUF@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
MMD1_k127_61277_19	370438.PTH_1804	7.452e-65	227.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,25CGM@186801|Clostridia,261GR@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
MMD1_k127_61277_14	289376.THEYE_A0953	9.274e-85	297.0	COG0568@1|root,COG0568@2|Bacteria,3J0E4@40117|Nitrospirae	40117|Nitrospirae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
MMD1_k127_61277_13	706587.Desti_4617	2.768e-87	299.0	COG0482@1|root,COG0482@2|Bacteria,1QV6H@1224|Proteobacteria,43BNM@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain	-	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	ThiI,tRNA_Me_trans
MMD1_k127_61277_30	1262914.BN533_01797	4.557e-12	69.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMD1_k127_61277_15	1232410.KI421428_gene1082	6.778e-80	274.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,42M2F@68525|delta/epsilon subdivisions,2WKUG@28221|Deltaproteobacteria,43THQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	regulatory protein IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
MMD1_k127_61277_12	246194.CHY_1281	1.298e-87	297.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,42FCT@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM PP-loop domain protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	NAD_synthase
MMD1_k127_61277_4	635013.TherJR_0831	9.098e-180	573.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,2609N@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
MMD1_k127_61277_22	693661.Arcve_0865	4.559e-55	201.0	COG0327@1|root,arCOG04454@2157|Archaea,2XT5G@28890|Euryarchaeota,246Y5@183980|Archaeoglobi	183980|Archaeoglobi	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
MMD1_k127_61277_23	706587.Desti_1130	1.949e-54	198.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2WPG2@28221|Deltaproteobacteria,2MRQB@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
MMD1_k127_61277_24	768706.Desor_3666	1.618e-49	196.0	COG1578@1|root,COG1578@2|Bacteria,1UURD@1239|Firmicutes,2492C@186801|Clostridia,261E1@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
MMD1_k127_61277_25	56780.SYN_02443	2.823e-48	180.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WNB6@28221|Deltaproteobacteria,2MS22@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
MMD1_k127_61277_7	404380.Gbem_2290	3.135e-172	553.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
MMD1_k127_61277_10	484770.UFO1_0279	1.544e-96	327.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,4H2FP@909932|Negativicutes	909932|Negativicutes	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
MMD1_k127_61277_5	697281.Mahau_2246	2.045e-178	576.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
MMD1_k127_61277_32	1121381.JNIV01000007_gene2246	2.003e-05	53.0	COG2165@1|root,COG2165@2|Bacteria,1WNE3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
MMD1_k127_61277_0	443143.GM18_1371	1.759e-282	927.0	COG2304@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions	1224|Proteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,PA14
MMD1_k127_6764_5	316067.Geob_3387	1.296e-25	108.0	COG0745@1|root,COG0745@2|Bacteria,1R9AR@1224|Proteobacteria,42YHD@68525|delta/epsilon subdivisions,2WU58@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
MMD1_k127_6764_1	2325.TKV_c20090	3.201e-86	293.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,42F6P@68295|Thermoanaerobacterales	186801|Clostridia	D	CO dehydrogenase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
MMD1_k127_6764_4	1121422.AUMW01000010_gene1079	8.578e-40	154.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,26269@186807|Peptococcaceae	186801|Clostridia	H	PFAM 5-formyltetrahydrofolate cyclo-ligase	yqgN	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
MMD1_k127_6764_2	935837.JAEK01000011_gene214	1.001e-73	252.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli,1ZAZD@1386|Bacillus	91061|Bacilli	H	GTP cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
MMD1_k127_6764_3	1121405.dsmv_2895	9.357e-67	233.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,42SBS@68525|delta/epsilon subdivisions,2WPKY@28221|Deltaproteobacteria,2MKW7@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_9
MMD1_k127_6764_0	1121405.dsmv_2896	7.992e-117	382.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria,2MKTG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
MMD1_k127_6764_6	1121405.dsmv_2897	2.091e-18	85.0	COG1148@1|root,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria,2MIJ3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
MMD1_k127_725481_9	768704.Desmer_2708	2.75e-25	118.0	COG3070@1|root,COG3070@2|Bacteria,1W1DT@1239|Firmicutes,254ET@186801|Clostridia,26614@186807|Peptococcaceae	186801|Clostridia	K	PFAM TfoX N-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
MMD1_k127_725481_7	316067.Geob_2909	1.547e-37	155.0	COG0745@1|root,COG0745@2|Bacteria,1N0WF@1224|Proteobacteria,42TTF@68525|delta/epsilon subdivisions,2WR69@28221|Deltaproteobacteria,43SMH@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
MMD1_k127_725481_5	1158345.JNLL01000001_gene100	1.127e-74	261.0	COG2607@1|root,COG2607@2|Bacteria	2|Bacteria	E	Atpase (Aaa	MA20_41470	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
MMD1_k127_725481_8	1111728.ATYS01000030_gene4496	2.842e-33	137.0	29XNE@1|root,30JDU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_725481_6	1278073.MYSTI_06384	5.113e-70	248.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WN9P@28221|Deltaproteobacteria,2Z0H8@29|Myxococcales	28221|Deltaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
MMD1_k127_725481_0	269799.Gmet_1215	0.0	1251.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,43SUG@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
MMD1_k127_725481_2	1123376.AUIU01000014_gene728	6.269e-115	377.0	COG0501@1|root,COG0501@2|Bacteria,3J0QG@40117|Nitrospirae	40117|Nitrospirae	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
MMD1_k127_725481_10	1382306.JNIM01000001_gene3449	1.987e-18	92.0	COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
MMD1_k127_725481_1	1382356.JQMP01000003_gene2232	5.351e-298	935.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,27XY6@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
MMD1_k127_725481_3	330214.NIDE3950	5.876e-97	329.0	COG0320@1|root,COG0320@2|Bacteria,3J0IY@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
MMD1_k127_725481_4	316067.Geob_2114	5.099e-91	305.0	COG1215@1|root,COG1215@2|Bacteria,1R6YR@1224|Proteobacteria,43CDN@68525|delta/epsilon subdivisions,2WK5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	N-terminal domain of galactosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
MMD1_k127_735146_2	243231.GSU0285	1.777e-118	385.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria,43S0X@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
MMD1_k127_735146_10	370438.PTH_0500	3.951e-13	71.0	COG2002@1|root,COG2002@2|Bacteria,1W48M@1239|Firmicutes,255K1@186801|Clostridia	186801|Clostridia	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
MMD1_k127_735146_6	370438.PTH_0499	3.63e-31	129.0	COG1848@1|root,COG1848@2|Bacteria,1VKNI@1239|Firmicutes,24VDB@186801|Clostridia,266AG@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
MMD1_k127_735146_5	289376.THEYE_A1165	1.46e-47	177.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
MMD1_k127_735146_1	289376.THEYE_A1165	1.128e-129	426.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
MMD1_k127_735146_4	666681.M301_1307	8.064e-60	214.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2WFPF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
MMD1_k127_735146_7	335543.Sfum_2301	5.22e-30	121.0	COG1942@1|root,COG1942@2|Bacteria,1N6WW@1224|Proteobacteria,42V9V@68525|delta/epsilon subdivisions,2WRUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM 4-oxalocrotonate tautomerase family enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
MMD1_k127_735146_0	243231.GSU3333	1.441e-131	427.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,43TP3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	NeuB family	aroG-1	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
MMD1_k127_735146_3	1034943.BN1094_02225	3.88e-99	338.0	COG1372@1|root,COG1465@1|root,COG4395@1|root,COG1372@2|Bacteria,COG1465@2|Bacteria,COG4395@2|Bacteria	2|Bacteria	S	Tim44	MA20_24770	-	1.1.98.6,1.4.1.24,3.6.3.14,3.6.3.15,4.1.1.35,4.1.99.20	ko:K02117,ko:K08678,ko:K11646,ko:K15539,ko:K17835,ko:K21636	ko00190,ko00230,ko00240,ko00400,ko00520,ko01100,ko01110,ko01130,map00190,map00230,map00240,map00400,map00520,map01100,map01110,map01130	M00053,M00159,M00361	R01384,R08569,R11633,R11634,R11635,R11636	RC00508,RC00613,RC02302	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	DHQS,Tim44
MMD1_k127_742971_1	96561.Dole_1197	3.028e-72	256.0	28MK7@1|root,2ZAWI@2|Bacteria,1R83K@1224|Proteobacteria,42MZ5@68525|delta/epsilon subdivisions,2WKYR@28221|Deltaproteobacteria,2MISC@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_742971_0	321332.CYB_0455	1.732e-88	303.0	COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria,1GZKF@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
MMD1_k127_756173_49	1123508.JH636439_gene332	4.851e-15	86.0	COG2373@1|root,COG2931@1|root,COG3209@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,2J3BU@203682|Planctomycetes	203682|Planctomycetes	Q	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_756173_29	1333856.L686_04750	2.084e-56	210.0	COG1835@1|root,COG1835@2|Bacteria,1RKTJ@1224|Proteobacteria,1S96U@1236|Gammaproteobacteria,1Z23W@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	I	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMD1_k127_756173_22	290397.Adeh_3069	2.312e-86	307.0	COG0760@1|root,COG0760@2|Bacteria,1NQ2Y@1224|Proteobacteria,42XX8@68525|delta/epsilon subdivisions,2WSSQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
MMD1_k127_756173_2	316067.Geob_3160	3.746e-276	863.0	COG3005@1|root,COG3005@2|Bacteria,1QYGG@1224|Proteobacteria,42NFU@68525|delta/epsilon subdivisions,2WKHN@28221|Deltaproteobacteria,43UCU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_756173_7	316067.Geob_3159	4.026e-173	555.0	COG3043@1|root,COG3043@2|Bacteria,1RG8Q@1224|Proteobacteria,42S2W@68525|delta/epsilon subdivisions,2WNP8@28221|Deltaproteobacteria,43V2D@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	pccJ	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_756173_23	243231.GSU2493	6.48e-82	282.0	COG3391@1|root,COG3391@2|Bacteria,1NUYI@1224|Proteobacteria,42ZRG@68525|delta/epsilon subdivisions,2WV3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
MMD1_k127_756173_33	1242864.D187_006518	2.717e-52	210.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2X8PP@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
MMD1_k127_756173_41	1167006.UWK_02411	7.518e-37	153.0	COG3594@1|root,COG3594@2|Bacteria,1R5HM@1224|Proteobacteria	1224|Proteobacteria	G	Thought to be an acetyltransferase that modifies the fucose of the nod factor	nolL	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
MMD1_k127_756173_13	195522.BD01_1492	6.268e-123	404.0	COG0438@1|root,arCOG01410@2157|Archaea,2Y2DM@28890|Euryarchaeota	28890|Euryarchaeota	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_756173_42	269799.Gmet_1390	2.65e-36	148.0	COG2227@1|root,COG2227@2|Bacteria,1NB77@1224|Proteobacteria	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
MMD1_k127_756173_38	324602.Caur_1283	3.106e-42	170.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
MMD1_k127_756173_35	56780.SYN_00826	4.141e-51	202.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25,NodS
MMD1_k127_756173_54	1068980.ARVW01000001_gene2961	1.18e-09	69.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4E1XV@85010|Pseudonocardiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
MMD1_k127_756173_36	926562.Oweho_3009	1.935e-43	172.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
MMD1_k127_756173_6	1173028.ANKO01000250_gene2401	8.098e-187	590.0	COG0399@1|root,COG0399@2|Bacteria,1G0XH@1117|Cyanobacteria,1H93R@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
MMD1_k127_756173_31	1173028.ANKO01000250_gene2400	7.088e-53	196.0	2BWTW@1|root,315N7@2|Bacteria,1G5TV@1117|Cyanobacteria,1HB33@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_756173_8	887062.HGR_06851	5.15e-141	454.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2WH4T@28216|Betaproteobacteria,4AJV7@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD1_k127_756173_10	404380.Gbem_2933	1.979e-128	430.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
MMD1_k127_756173_5	234267.Acid_2163	1.072e-194	615.0	COG1215@1|root,COG1215@2|Bacteria,3Y74D@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD1_k127_756173_1	404589.Anae109_1032	1.25e-277	885.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
MMD1_k127_756173_53	1202768.JROF01000005_gene2336	5.894e-10	70.0	arCOG02329@1|root,arCOG06796@1|root,arCOG07605@1|root,arCOG02329@2157|Archaea,arCOG06796@2157|Archaea,arCOG07605@2157|Archaea,2Y5ZU@28890|Euryarchaeota	28890|Euryarchaeota	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9
MMD1_k127_756173_59	935837.JAEK01000004_gene4843	8.006e-05	54.0	COG4565@1|root,COG4565@2|Bacteria,1V1D7@1239|Firmicutes,4HFWB@91061|Bacilli,1ZFEC@1386|Bacillus	91061|Bacilli	T	response regulator	citT	-	-	ko:K11638	ko02020,map02020	M00487	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	CitT,HTH_11,Response_reg
MMD1_k127_756173_27	335543.Sfum_1729	1.089e-63	222.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,42SQU@68525|delta/epsilon subdivisions,2WPRP@28221|Deltaproteobacteria,2MRV2@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
MMD1_k127_756173_3	335543.Sfum_1730	1.07e-236	755.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42NU9@68525|delta/epsilon subdivisions,2WKXG@28221|Deltaproteobacteria,2MRDM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
MMD1_k127_756173_25	243231.GSU0202	1.764e-66	237.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,42QUY@68525|delta/epsilon subdivisions,2WMVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3,XdhC_C,XdhC_CoxI
MMD1_k127_756173_37	1232410.KI421421_gene3617	7.44e-43	164.0	COG2068@1|root,COG2068@2|Bacteria,1RAAE@1224|Proteobacteria,42QNZ@68525|delta/epsilon subdivisions,2WMYX@28221|Deltaproteobacteria,43V5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	HD,NTP_transf_3
MMD1_k127_756173_15	1123376.AUIU01000011_gene1105	2.456e-111	368.0	COG0123@1|root,COG0123@2|Bacteria,3J0P2@40117|Nitrospirae	40117|Nitrospirae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
MMD1_k127_756173_43	717231.Flexsi_2276	1.239e-35	141.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	yhbS	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
MMD1_k127_756173_0	443143.GM18_0728	1.238e-302	936.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ABC transporter related	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
MMD1_k127_756173_48	289376.THEYE_A0748	1.77e-18	89.0	2E7Z7@1|root,332DJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_756173_34	1304885.AUEY01000005_gene887	3.028e-51	183.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,42TQH@68525|delta/epsilon subdivisions,2WQ2M@28221|Deltaproteobacteria,2MNRY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1255)	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
MMD1_k127_756173_26	289377.HL41_00595	2.651e-65	231.0	COG2077@1|root,COG2077@2|Bacteria,2GI9W@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	Redoxin	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
MMD1_k127_756173_44	289376.THEYE_A1158	2.976e-27	116.0	COG0723@1|root,COG0723@2|Bacteria,3J0TT@40117|Nitrospirae	40117|Nitrospirae	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
MMD1_k127_756173_24	1123376.AUIU01000013_gene1696	2.521e-78	267.0	COG1290@1|root,COG1290@2|Bacteria,3J0Q6@40117|Nitrospirae	40117|Nitrospirae	C	Cytochrome b/b6/petB	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
MMD1_k127_756173_51	589865.DaAHT2_2405	5.845e-11	66.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,42VCF@68525|delta/epsilon subdivisions,2WRI6@28221|Deltaproteobacteria,2MNRQ@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
MMD1_k127_756173_32	589865.DaAHT2_0148	2.014e-52	191.0	COG0607@1|root,COG0607@2|Bacteria,1NN37@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
MMD1_k127_756173_18	1123371.ATXH01000001_gene1283	3.389e-98	327.0	arCOG10218@1|root,320QR@2|Bacteria,2GIG0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
MMD1_k127_756173_40	404380.Gbem_1533	2.599e-37	160.0	COG4191@1|root,COG4191@2|Bacteria,1R9AK@1224|Proteobacteria,42Q2G@68525|delta/epsilon subdivisions,2WM8Y@28221|Deltaproteobacteria,43RXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMD1_k127_756173_14	404589.Anae109_4152	3.282e-120	404.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YX5F@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	nla19	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
MMD1_k127_756173_57	1122221.JHVI01000012_gene927	2.65e-06	58.0	COG0589@1|root,COG0589@2|Bacteria,1WMQ9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_756173_45	1461580.CCAS010000015_gene1869	6.701e-27	119.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus	91061|Bacilli	K	transcriptional	yvoA	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
MMD1_k127_756173_17	477974.Daud_1975	1.62e-107	361.0	COG0730@1|root,COG0730@2|Bacteria,1UI7C@1239|Firmicutes,24DK7@186801|Clostridia,2645M@186807|Peptococcaceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_756173_9	1123257.AUFV01000002_gene2395	1.437e-130	432.0	COG2391@1|root,COG2391@2|Bacteria,1PF9B@1224|Proteobacteria,1SH3M@1236|Gammaproteobacteria,1XBJT@135614|Xanthomonadales	135614|Xanthomonadales	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
MMD1_k127_756173_46	396588.Tgr7_0064	1.038e-25	108.0	COG0425@1|root,COG0425@2|Bacteria,1QSN1@1224|Proteobacteria,1SS7P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
MMD1_k127_756173_55	192952.MM_1453	1.71e-09	64.0	COG0589@1|root,arCOG02053@2157|Archaea,2XY1H@28890|Euryarchaeota	28890|Euryarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	usp26	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_756173_19	1128427.KB904821_gene4001	2.119e-97	336.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1H8M6@1150|Oscillatoriales	1117|Cyanobacteria	H	Protoporphyrinogen oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
MMD1_k127_756173_4	589865.DaAHT2_2411	8.881e-207	653.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MI4U@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
MMD1_k127_756173_39	1121441.AUCX01000021_gene718	5.087e-40	168.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43AVT@68525|delta/epsilon subdivisions,2X69W@28221|Deltaproteobacteria,2MH0D@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
MMD1_k127_756173_12	1167006.UWK_02795	4.14e-124	412.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MJ2S@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
MMD1_k127_756173_30	1307761.L21SP2_0943	4.441e-54	205.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	yeeE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
MMD1_k127_756173_58	1120965.AUBV01000010_gene2847	5.226e-06	55.0	COG0589@1|root,COG0589@2|Bacteria,4NHBB@976|Bacteroidetes,47XGM@768503|Cytophagia	976|Bacteroidetes	T	Universal stress protein family	uspA	-	-	-	-	-	-	-	-	-	-	-	DUF2007,Usp
MMD1_k127_756173_50	243232.MJ_0577	4.021e-11	70.0	COG0589@1|root,arCOG00449@2157|Archaea,2XV1Y@28890|Euryarchaeota	28890|Euryarchaeota	T	COG0589 Universal stress protein UspA and related nucleotide-binding	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_756173_52	224719.Abm4_0393	1.325e-10	70.0	COG0589@1|root,arCOG00449@2157|Archaea,2Y8D8@28890|Euryarchaeota	28890|Euryarchaeota	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
MMD1_k127_756173_11	596151.DesfrDRAFT_1899	6.673e-128	423.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M88@68525|delta/epsilon subdivisions,2WIZI@28221|Deltaproteobacteria,2MG1S@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
MMD1_k127_756173_16	589865.DaAHT2_2410	6.877e-109	370.0	COG0535@1|root,COG0535@2|Bacteria,1RADC@1224|Proteobacteria,42RDA@68525|delta/epsilon subdivisions,2WN4I@28221|Deltaproteobacteria,2MM5N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
MMD1_k127_756173_21	589865.DaAHT2_2409	4.1e-88	302.0	COG1216@1|root,COG1216@2|Bacteria,1R13V@1224|Proteobacteria,43D64@68525|delta/epsilon subdivisions,2X8CV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
MMD1_k127_756173_56	589865.DaAHT2_2406	1.84e-08	60.0	COG2044@1|root,COG2044@2|Bacteria,1ND3U@1224|Proteobacteria,43D63@68525|delta/epsilon subdivisions,2WRC1@28221|Deltaproteobacteria,2MP7X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_756173_61	555779.Dthio_PD1184	0.0001385	46.0	2AI22@1|root,318FT@2|Bacteria,1NNYG@1224|Proteobacteria,42X01@68525|delta/epsilon subdivisions,2WSTE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_756173_60	1085623.GNIT_1056	0.0001049	53.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,4643B@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	peptidylprolyl isomerase	ppiD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
MMD1_k127_759324_5	316067.Geob_1341	4.863e-27	113.0	2C5I4@1|root,33FNH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_759324_3	243231.GSU1013	2.212e-59	217.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria,43TEW@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
MMD1_k127_759324_1	330214.NIDE3808	1.935e-106	355.0	COG0719@1|root,COG0719@2|Bacteria,3J1E6@40117|Nitrospirae	40117|Nitrospirae	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
MMD1_k127_759324_2	573063.Metin_1116	2.449e-63	225.0	COG0396@1|root,arCOG04236@2157|Archaea,2XT6T@28890|Euryarchaeota,23QIQ@183939|Methanococci	183939|Methanococci	E	PFAM ABC transporter related	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
MMD1_k127_759324_7	1038860.AXAP01000128_gene3962	1.812e-07	54.0	COG0316@1|root,COG0316@2|Bacteria,1MZTE@1224|Proteobacteria,2UC0W@28211|Alphaproteobacteria,3JZJ2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
MMD1_k127_759324_4	760568.Desku_0316	9.035e-43	162.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,26390@186807|Peptococcaceae	186801|Clostridia	T	Catalyzes the reduction of arsenate As(V) to arsenite As(III)	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
MMD1_k127_759324_6	909663.KI867150_gene272	3.853e-24	111.0	COG1361@1|root,COG1470@1|root,COG3291@1|root,COG1361@2|Bacteria,COG1470@2|Bacteria,COG3291@2|Bacteria,1R5HW@1224|Proteobacteria,42R1Y@68525|delta/epsilon subdivisions,2WMXD@28221|Deltaproteobacteria,2MS7R@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
MMD1_k127_759324_0	335543.Sfum_2600	3.247e-150	482.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,2MSJJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
MMD1_k127_759324_8	765420.OSCT_1108	8.741e-06	49.0	COG1413@1|root,COG2909@1|root,COG3629@1|root,COG1413@2|Bacteria,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi,375JR@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HEAT_2,Trans_reg_C
MMD1_k127_779383_0	335543.Sfum_3260	6.233e-86	297.0	COG2334@1|root,COG2334@2|Bacteria,1Q18Y@1224|Proteobacteria,42PIW@68525|delta/epsilon subdivisions,2WK5A@28221|Deltaproteobacteria,2MR3W@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
MMD1_k127_779383_3	1502770.JQMG01000001_gene571	3.223e-36	139.0	COG2827@1|root,COG2827@2|Bacteria,1MZ4K@1224|Proteobacteria,2WFDD@28216|Betaproteobacteria	28216|Betaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
MMD1_k127_779383_1	404380.Gbem_0757	1.012e-58	211.0	COG4976@1|root,COG4976@2|Bacteria,1QZ2B@1224|Proteobacteria,43CEI@68525|delta/epsilon subdivisions,2X7X4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
MMD1_k127_779383_4	620914.JH621281_gene133	5.364e-08	63.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2,YCII
MMD1_k127_779383_2	443143.GM18_1006	7.763e-54	205.0	COG1520@1|root,COG4932@1|root,COG1520@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_791910_10	757424.Hsero_0376	8.784e-109	357.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VMYS@28216|Betaproteobacteria,473FP@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
MMD1_k127_791910_9	404589.Anae109_3869	2.451e-120	392.0	COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,43AF8@68525|delta/epsilon subdivisions,2X607@28221|Deltaproteobacteria,2Z387@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
MMD1_k127_791910_8	264462.Bd2750	3.468e-129	422.0	COG0715@1|root,COG0715@2|Bacteria,1MZ8F@1224|Proteobacteria,42Q55@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	PFAM NMT1 THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
MMD1_k127_791910_11	477974.Daud_1944	5.172e-84	283.0	COG0778@1|root,COG0778@2|Bacteria,1V4ZI@1239|Firmicutes,24BD0@186801|Clostridia,261YM@186807|Peptococcaceae	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
MMD1_k127_791910_25	298654.FraEuI1c_4959	3.053e-17	91.0	COG0730@1|root,COG0730@2|Bacteria,2GJCC@201174|Actinobacteria,4ESMQ@85013|Frankiales	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_791910_15	335543.Sfum_1521	4.969e-52	188.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WSRV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
MMD1_k127_791910_1	1125863.JAFN01000001_gene1801	6.338e-237	742.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
MMD1_k127_791910_24	1123376.AUIU01000014_gene586	1.814e-25	108.0	COG2920@1|root,COG2920@2|Bacteria	2|Bacteria	P	part of a sulfur-relay system	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
MMD1_k127_791910_14	289376.THEYE_A1650	5.516e-56	200.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
MMD1_k127_791910_21	1232437.KL662010_gene1569	9.963e-41	156.0	COG1433@1|root,COG1433@2|Bacteria,1N56C@1224|Proteobacteria,42TK7@68525|delta/epsilon subdivisions,2WQ0G@28221|Deltaproteobacteria,2MKGU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
MMD1_k127_791910_12	1487923.DP73_13575	4.046e-63	222.0	COG1280@1|root,COG1280@2|Bacteria,1V4SU@1239|Firmicutes,24KYP@186801|Clostridia,262BI@186807|Peptococcaceae	186801|Clostridia	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
MMD1_k127_791910_19	706587.Desti_2521	6.438e-42	161.0	COG1145@1|root,COG1145@2|Bacteria,1PW12@1224|Proteobacteria,42MZ9@68525|delta/epsilon subdivisions,2WN0W@28221|Deltaproteobacteria,2MR02@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
MMD1_k127_791910_2	671143.DAMO_0054	7.189e-184	587.0	COG1982@1|root,COG1982@2|Bacteria,2NNUZ@2323|unclassified Bacteria	2|Bacteria	E	Orn/Lys/Arg decarboxylase, C-terminal domain	speA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564	4.1.1.18,4.1.1.19	ko:K01582,ko:K01585	ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110	M00133	R00462,R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
MMD1_k127_791910_7	671143.DAMO_0053	2.082e-129	420.0	COG0421@1|root,COG0421@2|Bacteria,2NPMY@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
MMD1_k127_791910_16	1123376.AUIU01000013_gene1779	1.081e-51	187.0	COG1586@1|root,COG1586@2|Bacteria,3J15H@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
MMD1_k127_791910_23	1366050.N234_13205	1.649e-28	121.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VRUY@28216|Betaproteobacteria,1KFMP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
MMD1_k127_791910_3	555088.DealDRAFT_1104	2.494e-181	587.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42KCS@68298|Syntrophomonadaceae	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
MMD1_k127_791910_6	1336243.JAEA01000017_gene609	5.395e-131	426.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TSKV@28211|Alphaproteobacteria,1JT9A@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
MMD1_k127_791910_0	314345.SPV1_09408	0.0	1319.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria	1224|Proteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
MMD1_k127_791910_5	314345.SPV1_09403	4.064e-134	437.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrE	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
MMD1_k127_791910_4	443143.GM18_3568	2.349e-157	513.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKE@68525|delta/epsilon subdivisions,2WJTK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
MMD1_k127_791910_22	935948.KE386494_gene350	1.467e-29	124.0	COG1247@1|root,COG1247@2|Bacteria,1UHYR@1239|Firmicutes,24H0A@186801|Clostridia,42G6C@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
MMD1_k127_791910_13	56780.SYN_00929	6.749e-61	232.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N46@68525|delta/epsilon subdivisions,2WJT4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
MMD1_k127_791910_17	614083.AWQR01000051_gene3435	1.16e-48	195.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	BLUF,CHASE8,GGDEF,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,dCache_1,dCache_3
MMD1_k127_791910_20	156889.Mmc1_0977	1.169e-41	159.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase	MA20_24380	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
MMD1_k127_819729_1	1304885.AUEY01000017_gene3724	5.002e-56	203.0	2D5F0@1|root,32TIY@2|Bacteria,1N1FC@1224|Proteobacteria,42VZP@68525|delta/epsilon subdivisions,2WW0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_819729_2	1123284.KB899048_gene1596	1.197e-16	87.0	COG2306@1|root,COG2306@2|Bacteria,1VTFM@1239|Firmicutes,4HURM@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF402
MMD1_k127_819729_0	123214.PERMA_0258	5.629e-109	362.0	COG1893@1|root,COG1893@2|Bacteria,2G45N@200783|Aquificae	200783|Aquificae	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008677,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
MMD1_k127_832274_0	1232410.KI421419_gene2478	0.0	1015.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,43RYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
MMD1_k127_832274_3	289376.THEYE_A0132	7.775e-46	169.0	COG0234@1|root,COG0234@2|Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
MMD1_k127_832274_4	1121920.AUAU01000011_gene157	4.781e-42	173.0	2CBXN@1|root,2ZJNV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_832274_1	909663.KI867150_gene1101	1.915e-108	362.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,42T6P@68525|delta/epsilon subdivisions,2X5AV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
MMD1_k127_832274_2	1158338.JNLJ01000001_gene262	7.367e-81	275.0	COG2360@1|root,COG2360@2|Bacteria	2|Bacteria	O	leucyltransferase activity	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
MMD1_k127_83801_2	697281.Mahau_0417	6.072e-63	223.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,42FH5@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
MMD1_k127_83801_1	1123371.ATXH01000021_gene1141	7.81e-79	275.0	COG1355@1|root,COG1355@2|Bacteria,2GHI9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
MMD1_k127_83801_0	1125863.JAFN01000001_gene241	1.725e-138	451.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
MMD1_k127_843048_7	1121875.KB907551_gene1101	1.026e-06	50.0	COG0584@1|root,COG0584@2|Bacteria,4NP8K@976|Bacteroidetes,1I2H7@117743|Flavobacteriia	976|Bacteroidetes	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_843048_1	96561.Dole_2419	1.761e-21	101.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,2MJFK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
MMD1_k127_843048_3	1122918.KB907247_gene4691	7.658e-10	61.0	2EIAV@1|root,33C29@2|Bacteria,1VMAE@1239|Firmicutes,4HRG9@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_843048_2	398767.Glov_2384	2.144e-18	94.0	2ATWF@1|root,31JFP@2|Bacteria,1RK55@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_843048_6	794903.OPIT5_01705	8.795e-07	59.0	2DMI2@1|root,32RP8@2|Bacteria,46Y4T@74201|Verrucomicrobia,3K8XN@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_843048_5	179408.Osc7112_2687	6.803e-07	55.0	2AQY2@1|root,31G6Q@2|Bacteria,1GASS@1117|Cyanobacteria,1HDXN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_843048_0	1380394.JADL01000013_gene771	3.085e-86	295.0	COG4313@1|root,COG4313@2|Bacteria,1PXJ3@1224|Proteobacteria,2UAPJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
MMD1_k127_843048_8	926550.CLDAP_10820	1.848e-06	59.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	Lipoprotein_21,META,YscW
MMD1_k127_851226_2	338966.Ppro_0290	7.313e-27	112.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,43TYR@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
MMD1_k127_851226_0	1121920.AUAU01000006_gene400	2.325e-113	373.0	COG1752@1|root,COG1752@2|Bacteria,3Y5EY@57723|Acidobacteria	57723|Acidobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
MMD1_k127_851226_1	224324.aq_999	2.05e-75	267.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,2G3NC@200783|Aquificae	200783|Aquificae	I	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
MMD1_k127_861303_3	483219.LILAB_25485	1.352e-08	66.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,42X25@68525|delta/epsilon subdivisions,2WSPI@28221|Deltaproteobacteria,2Z3GD@29|Myxococcales	28221|Deltaproteobacteria	D	Sporulation related domain	agmI	-	-	-	-	-	-	-	-	-	-	-	SPOR
MMD1_k127_861303_0	648996.Theam_1729	3.036e-110	367.0	COG0809@1|root,COG0809@2|Bacteria,2G3KG@200783|Aquificae	200783|Aquificae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
MMD1_k127_861303_1	1232410.KI421418_gene2109	3.809e-57	213.0	COG0457@1|root,COG0457@2|Bacteria,1QXNU@1224|Proteobacteria,43C4R@68525|delta/epsilon subdivisions,2X7F5@28221|Deltaproteobacteria,43SFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_2,TPR_8
MMD1_k127_861303_2	370438.PTH_0986	6.601e-38	143.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,2623P@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
MMD1_k127_872830_2	1122165.AUHS01000006_gene532	2.346e-06	54.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1JCJ7@118969|Legionellales	118969|Legionellales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
MMD1_k127_872830_1	526227.Mesil_2782	2.072e-16	83.0	COG2010@1|root,COG2010@2|Bacteria,1WKCT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_872830_0	748247.AZKH_2518	5.41e-129	426.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2VK72@28216|Betaproteobacteria,2M004@206389|Rhodocyclales	206389|Rhodocyclales	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
MMD1_k127_879555_1	675635.Psed_1304	4.587e-163	532.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DXGB@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpV	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K12954,ko:K12956,ko:K17686,ko:K21887	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3,3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
MMD1_k127_879555_9	331678.Cphamn1_1575	7.233e-11	63.0	COG3197@1|root,COG3197@2|Bacteria	2|Bacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
MMD1_k127_879555_6	765914.ThisiDRAFT_2323	1.256e-37	150.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5V1@1236|Gammaproteobacteria,1WXWD@135613|Chromatiales	135613|Chromatiales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
MMD1_k127_879555_7	1280954.HPO_17325	1.598e-19	97.0	COG1309@1|root,COG1309@2|Bacteria,1MY6Y@1224|Proteobacteria,2UKSE@28211|Alphaproteobacteria,4408W@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
MMD1_k127_879555_8	291985.CCSI01000002_gene1452	2.65e-17	95.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,2JZY5@204457|Sphingomonadales	204457|Sphingomonadales	MU	membrane	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
MMD1_k127_879555_0	756272.Plabr_0942	1.365e-258	830.0	COG0841@1|root,COG0841@2|Bacteria,2IY0K@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
MMD1_k127_879555_5	243231.GSU2017	5.301e-58	211.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42SPW@68525|delta/epsilon subdivisions,2WP7F@28221|Deltaproteobacteria,43U6I@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
MMD1_k127_879555_4	552811.Dehly_0088	4.727e-69	249.0	COG1230@1|root,COG1230@2|Bacteria,2G6FI@200795|Chloroflexi,34D5R@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
MMD1_k127_879555_3	443143.GM18_2753	1.393e-117	387.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQAW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
MMD1_k127_879555_2	443143.GM18_2752	7.734e-142	452.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF1	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
MMD1_k127_900603_0	243231.GSU1077	2.274e-115	376.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,43TWH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
MMD1_k127_900603_9	404380.Gbem_1112	1.426e-36	157.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
MMD1_k127_900603_3	261292.Nit79A3_2578	1.596e-80	288.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,2W9WV@28216|Betaproteobacteria,373PI@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_900603_14	439235.Dalk_2217	1.638e-09	65.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,2MJFK@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
MMD1_k127_900603_6	880072.Desac_1869	1.207e-61	225.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2WMR5@28221|Deltaproteobacteria,2MQG3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
MMD1_k127_900603_5	338966.Ppro_1802	4.264e-66	240.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,43TQU@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM Stage II sporulation	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
MMD1_k127_900603_15	402777.KB235903_gene839	2.392e-06	58.0	COG0457@1|root,COG4122@1|root,COG4421@1|root,COG0457@2|Bacteria,COG4122@2|Bacteria,COG4421@2|Bacteria,1G29N@1117|Cyanobacteria,1H92V@1150|Oscillatoriales	1117|Cyanobacteria	G	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF563,Methyltransf_24,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_6,TPR_7,TPR_8
MMD1_k127_900603_16	1316936.K678_08259	4.406e-06	57.0	COG0457@1|root,COG2227@1|root,COG0457@2|Bacteria,COG2227@2|Bacteria,1QW6H@1224|Proteobacteria,2TRBZ@28211|Alphaproteobacteria,2JZ6I@204441|Rhodospirillales	204441|Rhodospirillales	H	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
MMD1_k127_900603_11	243231.GSU0618	8.031e-35	142.0	COG3303@1|root,COG3303@2|Bacteria,1RG2D@1224|Proteobacteria	1224|Proteobacteria	P	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
MMD1_k127_900603_2	123214.PERMA_1454	2.645e-83	290.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL,TPR_11
MMD1_k127_900603_8	1158338.JNLJ01000001_gene942	9.323e-45	174.0	COG0760@1|root,COG0760@2|Bacteria,2G5GE@200783|Aquificae	200783|Aquificae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
MMD1_k127_900603_13	1185876.BN8_03996	6.16e-20	104.0	2F7VW@1|root,3409W@2|Bacteria,4P3YN@976|Bacteroidetes,47VG8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_900603_10	443143.GM18_2426	1.631e-35	155.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,42RRN@68525|delta/epsilon subdivisions,2WNAY@28221|Deltaproteobacteria,43SI2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_900603_12	234267.Acid_5472	1.519e-26	127.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
MMD1_k127_900603_4	1131269.AQVV01000008_gene943	1.05e-72	259.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_31
MMD1_k127_900603_1	909663.KI867150_gene389	6.586e-112	370.0	COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,2MQ8C@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
MMD1_k127_900603_7	96561.Dole_1741	2.547e-50	196.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria,2MMKQ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
MMD1_k127_909702_0	330214.NIDE1016	2.479e-130	432.0	COG0768@1|root,COG0768@2|Bacteria,3J0FY@40117|Nitrospirae	40117|Nitrospirae	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
MMD1_k127_909702_3	671143.DAMO_3133	1.423e-08	65.0	COG2891@1|root,COG2891@2|Bacteria,2NRRJ@2323|unclassified Bacteria	2|Bacteria	M	rod shape-determining protein MreD	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
MMD1_k127_909702_2	1121405.dsmv_0472	6.522e-39	164.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
MMD1_k127_909702_1	289376.THEYE_A1842	2.024e-129	418.0	COG1077@1|root,COG1077@2|Bacteria,3J0BS@40117|Nitrospirae	40117|Nitrospirae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
MMD1_k127_913406_1	589865.DaAHT2_0739	9.652e-60	214.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,2MKSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
MMD1_k127_913406_0	1131269.AQVV01000006_gene503	4.018e-76	279.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
MMD1_k127_913406_2	279238.Saro_0829	6.873e-18	93.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2UBEB@28211|Alphaproteobacteria,2K5KS@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
MMD1_k127_919847_2	1047013.AQSP01000140_gene2513	1.029e-99	337.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
MMD1_k127_919847_0	373903.Hore_00620	2.594e-109	363.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WA9Y@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
MMD1_k127_919847_1	1121090.KB894686_gene3090	1.821e-107	357.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli,1ZCSH@1386|Bacillus	91061|Bacilli	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
MMD1_k127_919847_3	338966.Ppro_0282	3.42e-08	56.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RMJ@68525|delta/epsilon subdivisions,2WNP9@28221|Deltaproteobacteria,43T30@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
MMD1_k127_955944_0	768670.Calni_0830	1.155e-74	255.0	COG0059@1|root,COG0059@2|Bacteria,2GEM8@200930|Deferribacteres	200930|Deferribacteres	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
MMD1_k127_955944_1	330214.NIDE0998	1.064e-29	119.0	COG0440@1|root,COG0440@2|Bacteria,3J0K8@40117|Nitrospirae	40117|Nitrospirae	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
MMD1_k127_98551_2	269799.Gmet_1624	8.107e-59	212.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,43T8J@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
MMD1_k127_98551_1	331678.Cphamn1_1570	5.782e-78	267.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	yrfG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
MMD1_k127_98551_0	1265505.ATUG01000002_gene1588	2.618e-83	280.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria,2MN2H@213118|Desulfobacterales	28221|Deltaproteobacteria	E	AIR synthase related protein, N-terminal domain	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
MMD1_k127_9938_8	243231.GSU2551	4.606e-26	122.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42TT7@68525|delta/epsilon subdivisions,2WQR1@28221|Deltaproteobacteria,43TI3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
MMD1_k127_9938_4	1173028.ANKO01000199_gene3514	3.568e-72	256.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria,1HBYM@1150|Oscillatoriales	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
MMD1_k127_9938_5	404380.Gbem_3261	1.753e-70	246.0	arCOG03165@1|root,30AIC@2|Bacteria,1QYWT@1224|Proteobacteria,43CDP@68525|delta/epsilon subdivisions,2X7PJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
MMD1_k127_9938_6	316067.Geob_0760	1.235e-62	220.0	28HPC@1|root,2Z7XD@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
MMD1_k127_9938_2	243231.GSU2292	2.689e-149	481.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,43T2M@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
MMD1_k127_9938_9	335543.Sfum_1840	1.697e-24	111.0	COG3047@1|root,COG3047@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OMP_b-brl,OmpA_like
MMD1_k127_9938_0	56780.SYN_02058	1.367e-223	703.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MSKF@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
MMD1_k127_9938_3	56780.SYN_02059	1.259e-116	404.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MQHV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
MMD1_k127_9938_1	604354.TSIB_0718	1.24e-173	556.0	COG0477@1|root,arCOG00143@2157|Archaea,2Y8EH@28890|Euryarchaeota,245MX@183968|Thermococci	183968|Thermococci	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
MMD1_k127_9938_7	398767.Glov_1237	2.729e-61	213.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WP9B@28221|Deltaproteobacteria,43U3E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
## 2934 queries scanned
## Total time (seconds): 284.97568821907043
## Rate: 10.30 q/s